# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- TPR_10 PF13374.1 OAP53696.1 - 3.2e-18 65.0 3.5 3.4e-09 36.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAP53696.1 - 6.8e-17 61.1 1.2 7e-10 38.7 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF676 PF05057.9 OAP53696.1 - 0.00081 18.7 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 OAP53696.1 - 0.00083 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 OAP53696.1 - 0.0057 16.5 0.4 0.012 15.4 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 OAP53696.1 - 0.0073 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF726 PF05277.7 OAP53696.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) GYR PF02756.9 OAP53696.1 - 8.7 6.2 8.7 1.1 9.0 3.1 1.7 2 0 0 2 2 2 0 GYR motif DUF1315 PF07023.7 OAP53697.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1315) Nucleoplasmin PF03066.10 OAP53698.1 - 0.08 12.4 9.0 0.035 13.6 3.5 2.0 2 0 0 2 2 2 0 Nucleoplasmin Adeno_terminal PF02459.10 OAP53698.1 - 0.092 10.8 0.9 0.12 10.5 0.6 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Methyltransf_23 PF13489.1 OAP53704.1 - 3.2e-12 46.4 0.0 3.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP53704.1 - 0.00031 21.2 0.0 0.00042 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP53704.1 - 0.00034 20.2 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP53704.1 - 0.01 16.3 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAP53704.1 - 0.064 13.7 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 OAP53704.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.4 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Peptidase_A4 PF01828.12 OAP53707.1 - 4e-39 133.8 5.1 1.1e-21 76.9 0.3 2.1 1 1 1 2 2 2 2 Peptidase A4 family DUF3435 PF11917.3 OAP53708.1 - 6.2e-10 38.3 0.1 1.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Cyclin_N PF00134.18 OAP53709.1 - 1.5e-18 66.5 0.0 2e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.11 OAP53710.1 - 5 5.7 9.8 5.7 5.5 0.7 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily Peptidase_S8 PF00082.17 OAP53711.1 - 0.00025 20.3 0.0 0.00026 20.2 0.0 1.1 1 0 0 1 1 1 1 Subtilase family DUF3187 PF11383.3 OAP53711.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) CAF1C_H4-bd PF12265.3 OAP53712.1 - 0.0036 17.1 0.5 42 4.1 0.0 3.8 1 1 3 4 4 4 4 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF3328 PF11807.3 OAP53713.1 - 8.3e-37 126.9 0.0 9.8e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.1 OAP53714.1 - 2e-50 171.5 40.4 2.2e-50 171.4 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP53714.1 - 1e-22 80.1 36.6 1.4e-22 79.7 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.8 OAP53715.1 - 5e-58 196.1 0.2 6.7e-58 195.7 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP53715.1 - 1.6e-09 37.6 0.2 2.2e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 OAP53715.1 - 6.3e-08 31.7 0.3 1.8e-07 30.2 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 OAP53715.1 - 1.5e-07 31.5 2.4 2.8e-07 30.6 1.6 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP53715.1 - 9.4e-07 28.2 0.0 2.5e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 OAP53715.1 - 2.2e-05 23.8 0.5 0.00064 19.0 0.1 2.2 1 1 1 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 OAP53715.1 - 0.001 17.6 0.0 0.0015 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 OAP53715.1 - 0.0025 16.5 0.0 0.0034 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Esterase_phd PF10503.4 OAP53715.1 - 0.029 13.6 0.0 0.073 12.3 0.0 1.6 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydro_lipase PF04083.11 OAP53715.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Chlorophyllase2 PF12740.2 OAP53715.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Aldedh PF00171.17 OAP53716.1 - 1.6e-151 504.7 0.0 1.8e-151 504.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP53716.1 - 0.0018 17.0 0.2 0.0065 15.2 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) FAD_binding_2 PF00890.19 OAP53717.1 - 2.9e-35 121.9 1.3 5.4e-34 117.7 0.9 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAP53717.1 - 2e-05 23.8 0.0 6.5e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 OAP53717.1 - 0.0004 19.4 2.4 0.0014 17.6 1.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP53717.1 - 0.023 14.5 0.5 0.34 10.7 0.4 2.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 OAP53717.1 - 0.026 14.0 0.1 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 OAP53717.1 - 0.043 12.2 6.8 0.19 10.1 0.3 3.1 3 0 0 3 3 3 0 HI0933-like protein PALP PF00291.20 OAP53717.1 - 0.044 13.0 0.1 0.082 12.1 0.1 1.5 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Fork_head PF00250.13 OAP53717.1 - 0.069 13.1 0.1 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Fork head domain DUF743 PF05332.6 OAP53717.1 - 0.096 12.6 0.1 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF743) PEPcase_2 PF14010.1 OAP53717.1 - 0.16 10.2 0.0 0.24 9.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase GIDA PF01134.17 OAP53717.1 - 2.5 6.8 6.7 0.52 9.1 0.5 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Mito_carr PF00153.22 OAP53718.1 - 2.4e-57 190.6 9.1 1.2e-19 69.7 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein 4HBT_3 PF13622.1 OAP53721.1 - 1.3e-42 146.3 3.4 1.5e-42 146.1 2.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAP53721.1 - 3e-19 68.9 0.1 8.3e-11 41.6 0.0 4.0 2 2 0 2 2 2 2 Acyl-CoA thioesterase AfsA PF03756.8 OAP53721.1 - 0.0092 15.7 1.0 0.28 10.9 0.4 2.4 2 0 0 2 2 2 1 A-factor biosynthesis hotdog domain UNC-93 PF05978.11 OAP53722.1 - 4.6e-07 29.4 5.1 4.6e-07 29.4 3.6 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 OAP53722.1 - 0.052 12.2 49.1 0.0042 15.8 25.8 2.8 1 1 1 2 2 2 0 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.16 OAP53723.1 - 2e-19 69.5 0.0 2.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Amidase PF01425.16 OAP53724.1 - 7.7e-82 275.4 0.0 9e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 Amidase Transaldolase PF00923.14 OAP53725.1 - 5.5e-32 111.0 0.0 6.8e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Glyoxalase_2 PF12681.2 OAP53726.1 - 1.4e-12 48.2 0.0 2.7e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP53726.1 - 1.7e-07 31.2 0.0 2.8e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 OAP53726.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 OAP53726.1 - 0.00035 20.5 0.0 0.0065 16.3 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase-like domain Amino_oxidase PF01593.19 OAP53727.1 - 1.7e-46 159.2 0.1 1.2e-45 156.4 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP53727.1 - 3.6e-13 49.3 0.1 9.8e-13 47.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP53727.1 - 1.2e-07 31.0 0.1 2.1e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAP53727.1 - 3.9e-07 29.2 0.5 6e-07 28.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP53727.1 - 9.9e-07 27.9 0.1 0.00026 20.0 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP53727.1 - 3e-05 24.1 0.4 6.3e-05 23.1 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP53727.1 - 0.00032 19.8 0.5 0.00047 19.3 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAP53727.1 - 0.0011 18.1 0.6 0.0016 17.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP53727.1 - 0.0011 17.9 0.3 0.0017 17.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 OAP53727.1 - 0.0015 17.0 0.1 0.0022 16.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 OAP53727.1 - 0.0029 16.5 0.1 0.0048 15.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 OAP53727.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP53727.1 - 0.056 13.8 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 OAP53728.1 - 1.8e-22 80.0 0.0 2.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP53728.1 - 1.2e-12 48.1 0.0 1.6e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP53728.1 - 0.00017 21.2 0.0 0.00035 20.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.13 OAP53729.1 - 9.8e-27 93.4 0.1 1.7e-26 92.6 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP53729.1 - 6.4e-09 35.5 12.9 1.3e-08 34.5 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transglut_core PF01841.14 OAP53729.1 - 0.1 12.8 0.2 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily Peptidase_C14 PF00656.17 OAP53732.1 - 1.4e-18 67.5 0.0 2.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.2 OAP53733.1 - 4e-35 121.3 0.2 6.7e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 OAP53733.1 - 4.9e-13 48.8 34.2 0.0036 17.2 0.2 10.2 4 2 8 12 12 12 8 Tetratricopeptide repeat TPR_11 PF13414.1 OAP53733.1 - 2e-12 46.5 23.9 0.0028 17.2 0.0 9.0 5 3 5 11 11 11 6 TPR repeat TPR_10 PF13374.1 OAP53733.1 - 3.9e-06 26.6 23.6 0.067 13.1 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAP53733.1 - 0.00016 21.3 16.1 2.8 8.0 0.1 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat DUF2783 PF10932.3 OAP53733.1 - 0.055 12.9 3.6 11 5.5 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2783) TPR_1 PF00515.23 OAP53733.1 - 0.061 12.9 5.8 27 4.5 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Gp-FAR-1 PF05823.7 OAP53733.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DALR_1 PF05746.10 OAP53733.1 - 0.17 11.8 3.1 8.2 6.4 0.0 4.1 4 0 0 4 4 4 0 DALR anticodon binding domain FIVAR PF07554.8 OAP53733.1 - 1 9.6 3.7 4.6 7.5 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain HET PF06985.6 OAP53734.1 - 6.4e-31 107.3 0.5 3.1e-30 105.1 0.2 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CHAT PF12770.2 OAP53734.1 - 4.3e-27 94.9 0.0 1.1e-26 93.6 0.0 1.7 1 0 0 1 1 1 1 CHAT domain Peptidase_C14 PF00656.17 OAP53734.1 - 1e-16 61.4 0.0 2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Caspase domain DUF3310 PF11753.3 OAP53734.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) Fungal_trans PF04082.13 OAP53737.1 - 6.1e-10 38.4 0.1 2e-09 36.7 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Beta-lactamase PF00144.19 OAP53738.1 - 9.9e-61 205.5 0.0 1.2e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase adh_short PF00106.20 OAP53739.1 - 2e-37 128.6 2.3 2.5e-37 128.3 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP53739.1 - 5.6e-31 108.1 0.1 6.7e-31 107.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP53739.1 - 8.5e-18 64.6 0.8 1.2e-17 64.1 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP53739.1 - 4.7e-05 22.9 0.4 9.6e-05 21.9 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP53739.1 - 0.0013 18.8 0.7 0.0031 17.5 0.5 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP53739.1 - 0.0016 17.1 0.1 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 OAP53739.1 - 0.011 15.3 0.2 0.018 14.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 OAP53740.1 - 2.8e-25 89.5 0.0 4.3e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP53740.1 - 8e-17 60.6 0.2 2e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP53740.1 - 4.7e-14 52.0 0.1 4.1e-12 45.6 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP53740.1 - 7e-10 39.1 0.0 8.3e-05 22.5 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP53740.1 - 9.7e-10 38.3 0.2 9.6e-08 31.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 OAP53740.1 - 5.7e-07 29.7 0.0 0.00053 20.2 0.0 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 OAP53740.1 - 1.5e-06 28.0 0.6 0.0013 18.5 0.1 3.5 3 2 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 OAP53740.1 - 2.2e-06 27.9 0.5 0.1 13.0 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP53740.1 - 3.5e-05 22.8 7.8 0.008 15.1 0.6 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 OAP53740.1 - 4.6e-05 23.5 0.2 0.0049 16.9 0.0 3.2 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase CPSase_L_chain PF00289.17 OAP53740.1 - 0.0027 17.7 0.0 0.19 11.8 0.0 2.7 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Thi4 PF01946.12 OAP53740.1 - 0.0043 16.1 0.1 0.36 9.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 OAP53740.1 - 0.0045 16.4 0.4 0.036 13.4 0.0 2.6 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 OAP53740.1 - 0.005 15.3 0.6 0.52 8.7 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein 2-Hacid_dh_C PF02826.14 OAP53740.1 - 0.0091 15.1 0.0 0.029 13.5 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAP53740.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding FAD_binding_2 PF00890.19 OAP53740.1 - 0.017 13.9 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 OAP53740.1 - 0.024 13.5 0.0 0.75 8.6 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 OAP53740.1 - 0.036 13.7 0.4 0.92 9.1 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 OAP53740.1 - 0.059 12.9 0.2 5 6.6 0.1 2.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 OAP53740.1 - 0.086 12.6 0.0 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_5 PF12695.2 OAP53741.1 - 1.2e-07 31.5 0.1 1.7e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAP53741.1 - 2.1e-07 30.7 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP53741.1 - 1.2e-06 28.5 0.4 2.2e-06 27.7 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 OAP53741.1 - 0.0012 17.7 0.1 0.0023 16.7 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF1749 PF08538.5 OAP53741.1 - 0.0018 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF2424 PF10340.4 OAP53741.1 - 0.0048 15.5 0.0 0.0068 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Cupin_2 PF07883.6 OAP53742.1 - 4e-13 48.6 0.2 6.3e-09 35.2 0.0 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 OAP53742.1 - 9.7e-05 21.6 0.1 0.18 11.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 OAP53742.1 - 0.0008 19.1 0.1 0.0042 16.7 0.1 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 OAP53742.1 - 0.0038 16.8 0.0 0.9 9.1 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase CENP-C_C PF11699.3 OAP53742.1 - 0.018 14.9 0.2 3 7.8 0.0 2.3 2 0 0 2 2 2 0 Mif2/CENP-C like FdtA PF05523.6 OAP53742.1 - 0.092 12.2 0.0 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 WxcM-like, C-terminal Amidohydro_2 PF04909.9 OAP53743.1 - 1.4e-38 133.0 0.1 1.9e-38 132.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 OAP53744.1 - 1.3e-33 116.2 31.8 1.3e-33 116.2 22.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP53744.1 - 2.9e-05 22.8 8.8 2.9e-05 22.8 6.1 2.8 3 1 1 4 4 4 1 Sugar (and other) transporter ADH_N PF08240.7 OAP53745.1 - 0.0072 16.0 0.4 0.0095 15.6 0.3 1.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Acetyltransf_1 PF00583.19 OAP53747.1 - 5.3e-09 35.9 0.0 1.1e-08 35.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP53747.1 - 1e-06 28.7 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP53747.1 - 3.3e-06 27.1 0.0 5.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP53747.1 - 0.00023 21.0 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP53747.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein FAM110_C PF14160.1 OAP53747.1 - 0.11 13.4 0.0 0.16 12.8 0.0 1.2 1 0 0 1 1 1 0 Centrosome-associated C terminus Acetyltransf_CG PF14542.1 OAP53747.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Orn_DAP_Arg_deC PF00278.17 OAP53749.1 - 4.9e-09 35.9 0.0 5.6e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF2325 PF10087.4 OAP53750.1 - 0.06 13.1 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF3669 PF12417.3 OAP53756.1 - 0.06 13.0 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Zinc finger protein zf-C3HC4_2 PF13923.1 OAP53757.1 - 6.9e-08 32.3 6.6 1.2e-07 31.6 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP53757.1 - 9.4e-08 31.6 4.2 1.5e-07 30.9 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP53757.1 - 1.7e-07 30.7 5.9 3e-07 29.9 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP53757.1 - 2.1e-07 30.6 5.5 3.8e-07 29.8 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAP53757.1 - 6.5e-06 25.7 6.0 1.2e-05 24.9 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAP53757.1 - 0.00017 21.2 1.6 0.00017 21.2 1.1 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 OAP53757.1 - 0.0042 17.1 4.8 0.015 15.4 3.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 OAP53757.1 - 0.0068 16.2 4.8 0.016 15.0 3.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 OAP53757.1 - 0.024 14.4 1.3 0.048 13.5 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 OAP53757.1 - 0.039 13.7 0.8 0.039 13.7 0.5 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF1244 PF06844.6 OAP53757.1 - 0.076 12.8 0.2 0.23 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-UDP PF14569.1 OAP53757.1 - 0.11 12.3 1.6 0.18 11.5 1.1 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.16 OAP53757.1 - 0.13 12.1 5.5 0.32 10.9 3.4 1.9 1 1 0 1 1 1 0 FYVE zinc finger Phasin_2 PF09361.5 OAP53757.1 - 0.14 12.2 3.5 0.22 11.5 2.4 1.3 1 1 0 1 1 1 0 Phasin protein BssS PF13991.1 OAP53757.1 - 0.19 11.4 0.2 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 BssS protein family GlcNAc PF11397.3 OAP53757.1 - 0.21 10.6 1.7 0.29 10.1 1.2 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Exonuc_VII_L PF02601.10 OAP53757.1 - 0.24 10.5 5.0 0.32 10.1 3.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_4 PF14570.1 OAP53757.1 - 0.27 10.8 7.3 1.3 8.6 5.0 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain eIF3_N PF09440.5 OAP53757.1 - 0.31 11.1 6.1 0.45 10.6 4.2 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain V_ATPase_I PF01496.14 OAP53757.1 - 0.4 8.4 3.1 0.48 8.2 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KaiC PF06745.8 OAP53757.1 - 0.58 9.2 4.0 0.59 9.2 0.5 1.9 1 1 1 2 2 2 0 KaiC Macoilin PF09726.4 OAP53757.1 - 0.73 8.0 12.0 0.94 7.6 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Seryl_tRNA_N PF02403.17 OAP53757.1 - 0.78 9.7 12.6 1.7 8.6 8.7 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain KxDL PF10241.4 OAP53757.1 - 0.94 9.4 11.0 0.67 9.8 6.2 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein Spc42p PF11544.3 OAP53757.1 - 1.5 8.8 10.4 2 8.3 6.4 1.8 1 1 0 1 1 1 0 Spindle pole body component Spc42p TMPIT PF07851.8 OAP53757.1 - 1.7 7.6 6.9 2.2 7.2 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 OAP53757.1 - 1.9 8.0 12.0 2.5 7.6 8.3 1.2 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 OAP53757.1 - 3.1 6.6 13.2 5.7 5.7 9.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 OAP53757.1 - 4.3 7.4 11.9 4.1 7.5 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 OAP53757.1 - 4.7 7.2 13.3 15 5.6 9.3 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 OAP53757.1 - 7.6 6.4 12.8 1.2 8.9 4.1 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Clat_adaptor_s PF01217.15 OAP53759.1 - 0.00024 20.8 0.0 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3435 PF11917.3 OAP53763.1 - 1.4e-06 27.2 8.4 3.9e-06 25.8 5.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3435) AAA_13 PF13166.1 OAP53763.1 - 0.022 13.2 1.5 0.025 13.0 1.0 1.0 1 0 0 1 1 1 0 AAA domain zf-PHD-like PF15446.1 OAP53763.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain YqzE PF14038.1 OAP53763.1 - 0.28 10.9 2.2 9.9 5.9 0.0 3.0 3 0 0 3 3 3 0 YqzE-like protein UbiD PF01977.11 OAP53765.1 - 0.17 10.3 0.0 0.25 9.7 0.0 1.3 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ABC_membrane PF00664.18 OAP53768.1 - 2.3e-06 27.2 0.1 2.7e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region JmjC PF02373.17 OAP53769.1 - 4.7e-18 65.4 0.0 7.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Peptidase_C48 PF02902.14 OAP53771.1 - 0.0084 15.7 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain bZIP_1 PF00170.16 OAP53772.1 - 0.0001 22.1 9.0 0.00019 21.3 6.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP53772.1 - 0.0024 17.6 8.3 0.0046 16.7 5.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PLD_C PF12357.3 OAP53773.1 - 0.0079 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase D C terminal URO-D PF01208.12 OAP53775.1 - 3.4e-12 45.9 0.1 3.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SH3_9 PF14604.1 OAP53776.1 - 8.6e-11 41.2 0.0 1.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAP53776.1 - 6.7e-08 31.7 0.0 9e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAP53776.1 - 2.9e-06 26.6 0.0 4.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Replicase PF03090.12 OAP53777.1 - 0.045 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Replicase family adh_short PF00106.20 OAP53779.1 - 8.9e-17 61.5 0.1 1.6e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAP53779.1 - 1.5e-06 28.0 0.0 6e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAP53779.1 - 0.0072 16.1 0.0 0.09 12.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3124 PF11322.3 OAP53779.1 - 0.14 12.1 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) dCMP_cyt_deam_1 PF00383.17 OAP53780.1 - 1.1e-20 73.1 0.1 1.5e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 OAP53780.1 - 0.00019 21.3 1.3 0.11 12.2 0.8 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase XOO_2897-deam PF14440.1 OAP53780.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 OAP53780.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.5 1 1 0 1 1 1 0 APOBEC-like N-terminal domain URO-D PF01208.12 OAP53781.1 - 9.2e-24 83.9 0.0 9.9e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Abhydrolase_3 PF07859.8 OAP53782.1 - 9.9e-14 51.4 0.0 1.8e-08 34.1 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold T2SG PF08334.6 OAP53782.1 - 0.035 13.8 0.0 0.16 11.7 0.0 1.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein G COG6 PF06419.6 OAP53783.1 - 1e-30 106.5 2.5 6.2e-18 64.2 0.6 2.0 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 DUF4054 PF13262.1 OAP53783.1 - 0.025 14.8 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Redoxin PF08534.5 OAP53784.1 - 3.7e-19 68.7 0.0 4.5e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin SBDS_C PF09377.5 OAP53786.1 - 1.5e-06 27.9 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 SBDS protein C-terminal domain tRNA-synt_1 PF00133.17 OAP53786.1 - 0.12 10.2 0.0 0.16 9.9 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) ABC_trans_N PF14510.1 OAP53787.1 - 0.054 13.5 0.1 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 ABC-transporter extracellular N-terminal DUF4448 PF14610.1 OAP53789.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Pkinase PF00069.20 OAP53791.1 - 1.4e-30 106.3 0.0 2.8e-30 105.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP53791.1 - 1.8e-13 50.1 0.0 5.2e-13 48.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-binding PF00249.26 OAP53795.1 - 0.00052 20.0 3.0 0.0012 18.8 2.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAP53795.1 - 0.00074 19.5 2.9 0.0017 18.4 2.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DsrH PF04077.7 OAP53795.1 - 0.043 13.4 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 DsrH like protein F-box-like PF12937.2 OAP53796.1 - 0.0049 16.5 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like SCP-1 PF05483.7 OAP53797.1 - 0.023 12.4 0.2 0.032 12.0 0.1 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) DUF641 PF04859.7 OAP53797.1 - 0.045 13.5 0.8 0.077 12.7 0.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Cortex-I_coil PF09304.5 OAP53797.1 - 0.15 12.0 4.6 0.41 10.7 2.4 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DDE_3 PF13358.1 OAP53798.1 - 1.4e-13 50.8 0.5 2.7e-13 49.8 0.1 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 OAP53798.1 - 0.049 13.7 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DUF2204 PF09970.4 OAP53798.1 - 0.12 11.8 0.3 0.17 11.3 0.2 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Baculo_PEP_C PF04513.7 OAP53798.1 - 0.14 11.9 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Trypsin_2 PF13365.1 OAP53799.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain Papilloma_E5 PF03025.9 OAP53802.1 - 0.46 10.4 7.4 0.22 11.5 2.1 2.1 2 0 0 2 2 2 0 Papillomavirus E5 TrbE PF11100.3 OAP53802.1 - 3 7.7 6.1 0.54 10.1 0.4 2.2 2 1 0 2 2 2 0 Conjugal transfer protein TrbE NAD_binding_6 PF08030.7 OAP53803.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Zn_clus PF00172.13 OAP53805.1 - 0.00077 19.3 8.6 0.00077 19.3 6.0 3.9 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S64 PF08192.6 OAP53806.1 - 0.017 13.4 0.3 0.53 8.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S64 Trypsin_2 PF13365.1 OAP53806.1 - 0.084 12.8 0.1 0.59 10.1 0.0 2.3 1 1 0 1 1 1 0 Trypsin-like peptidase domain TRH PF05438.7 OAP53818.1 - 0.0027 17.1 0.8 0.0043 16.4 0.6 1.2 1 0 0 1 1 1 1 Thyrotropin-releasing hormone (TRH) Asp PF00026.18 OAP53822.1 - 5.3e-05 22.6 0.1 6.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF3052 PF11253.3 OAP53824.1 - 0.051 13.1 0.2 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Phage_lysozyme PF00959.14 OAP53825.1 - 0.11 12.8 0.8 0.24 11.6 0.5 1.6 1 0 0 1 1 1 0 Phage lysozyme Caudo_TAP PF02413.12 OAP53825.1 - 2.4 8.3 11.7 25 5.0 8.1 2.6 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF2877 PF11392.3 OAP53825.1 - 3.9 7.7 6.4 3 8.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2877) IL15 PF02372.10 OAP53825.1 - 7.9 6.2 7.2 12 5.6 0.3 3.2 2 1 0 3 3 3 0 Interleukin 15 F-box PF00646.28 OAP53827.1 - 0.0099 15.5 0.1 0.42 10.3 0.0 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 OAP53827.1 - 0.063 13.0 1.6 0.24 11.1 0.0 2.5 3 0 0 3 3 3 0 F-box-like APH PF01636.18 OAP53829.1 - 7.3e-14 52.0 0.2 2.5e-13 50.2 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family HipA_N PF07805.7 OAP53829.1 - 0.023 14.9 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 HipA-like N-terminal domain DUF1732 PF08340.6 OAP53830.1 - 3.1e-10 39.7 0.7 2.5e-09 36.8 0.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1732) YicC_N PF03755.8 OAP53830.1 - 1.1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 YicC-like family, N-terminal region Vps39_1 PF10366.4 OAP53839.1 - 0.42 10.6 2.2 0.4 10.7 0.2 1.9 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 Abhydrolase_3 PF07859.8 OAP53845.1 - 7e-11 42.1 0.0 1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M17_N PF02789.12 OAP53848.1 - 0.1 12.3 0.1 0.35 10.6 0.0 1.7 1 1 1 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain EBV-NA3 PF05009.7 OAP53849.1 - 0.021 14.0 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RVT_1 PF00078.22 OAP53851.1 - 1e-06 28.2 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GTSE1_N PF15259.1 OAP53855.1 - 0.11 12.4 0.5 6.1 6.7 0.1 2.3 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Eapp_C PF10238.4 OAP53858.1 - 0.057 13.3 2.4 0.11 12.4 1.6 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein zf-C3HC4_3 PF13920.1 OAP53859.1 - 1.2 8.8 6.4 0.4 10.3 1.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FancD2 PF14631.1 OAP53862.1 - 0.042 10.9 0.0 0.05 10.7 0.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease TGT PF01702.13 OAP53862.1 - 0.083 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase ETF_alpha PF00766.14 OAP53868.1 - 0.039 13.5 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain Bunya_G2 PF03563.8 OAP53870.1 - 0.0083 15.0 1.5 0.0092 14.9 1.0 1.2 1 0 0 1 1 1 1 Bunyavirus glycoprotein G2 RNA_pol_Rpb2_6 PF00562.23 OAP53871.1 - 0.00047 19.0 0.0 0.00063 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Lipoxygenase PF00305.14 OAP53872.1 - 6.7e-24 83.8 0.0 9e-24 83.4 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase Pyr_redox_3 PF13738.1 OAP53873.1 - 1.3e-23 84.1 0.0 2.3e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP53873.1 - 3.1e-14 52.0 0.1 1.5e-12 46.5 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP53873.1 - 2.4e-10 39.8 0.1 2.9e-08 33.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP53873.1 - 3.1e-10 39.9 0.0 2.9e-09 36.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP53873.1 - 6.6e-07 29.4 0.0 4.3e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP53873.1 - 1.8e-05 23.8 1.0 0.00085 18.3 0.2 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP53873.1 - 0.00051 18.9 0.0 0.00086 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 OAP53873.1 - 0.001 18.1 0.2 0.0027 16.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 OAP53873.1 - 0.0038 16.4 0.0 0.0075 15.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 OAP53873.1 - 0.0074 16.0 1.3 0.7 9.6 0.2 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAP53873.1 - 0.0097 15.0 0.0 0.11 11.6 0.0 2.4 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.15 OAP53873.1 - 0.1 12.6 0.0 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 OAP53873.1 - 0.13 11.0 0.0 11 4.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 OAP53874.1 - 1.4e-40 139.1 34.2 2.2e-38 131.9 15.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 OAP53874.1 - 1.1e-07 30.4 5.3 1.1e-07 30.4 3.7 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector Cellsynth_D PF03500.8 OAP53874.1 - 0.098 12.3 0.3 0.3 10.7 0.1 1.9 2 0 0 2 2 2 0 Cellulose synthase subunit D JmjC PF02373.17 OAP53875.1 - 4.2e-14 52.7 0.0 8.8e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase TOBE PF03459.12 OAP53875.1 - 0.052 13.6 0.1 2.7 8.1 0.0 3.3 4 0 0 4 4 4 0 TOBE domain bZIP_1 PF00170.16 OAP53876.1 - 8.3e-09 35.2 7.2 1.2e-08 34.8 5.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP53876.1 - 0.0033 17.2 9.4 0.005 16.6 6.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper TMEM192 PF14802.1 OAP53876.1 - 0.16 10.7 1.7 0.22 10.3 1.2 1.2 1 0 0 1 1 1 0 TMEM192 family DivIC PF04977.10 OAP53876.1 - 5.9 6.4 6.4 2.5 7.6 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF948 PF06103.6 OAP53877.1 - 0.0018 18.1 0.3 0.003 17.4 0.2 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 OAP53877.1 - 0.019 14.7 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II Syntaxin_2 PF14523.1 OAP53877.1 - 0.038 14.0 0.9 0.061 13.3 0.6 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Vps53_N PF04100.7 OAP53877.1 - 0.05 12.3 1.1 0.055 12.2 0.8 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal V_ATPase_I PF01496.14 OAP53877.1 - 0.16 9.7 1.8 0.17 9.7 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.7 OAP53877.1 - 0.27 11.6 4.1 0.28 11.5 1.1 2.3 2 1 0 2 2 2 0 SlyX APG6 PF04111.7 OAP53877.1 - 0.39 9.7 4.8 0.49 9.3 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 OAP53877.1 - 0.91 9.7 6.9 0.74 10.0 2.6 2.1 1 1 1 2 2 2 0 Syntaxin GLE1 PF07817.8 OAP53877.1 - 0.98 8.3 3.5 1.3 7.8 0.8 2.0 1 1 1 2 2 2 0 GLE1-like protein Mnd1 PF03962.10 OAP53877.1 - 3.1 7.4 8.2 2.7 7.6 4.3 1.8 1 1 1 2 2 2 0 Mnd1 family IncA PF04156.9 OAP53877.1 - 4 6.9 6.4 5.6 6.5 4.4 1.3 1 0 0 1 1 1 0 IncA protein Peptidase_S24 PF00717.18 OAP53880.1 - 0.019 14.5 0.5 0.68 9.6 0.0 2.7 3 0 0 3 3 3 0 Peptidase S24-like DUF3435 PF11917.3 OAP53881.1 - 3.9e-08 32.4 0.0 5e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) PPR PF01535.15 OAP53881.1 - 0.035 14.0 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 PPR repeat DUF3787 PF12655.2 OAP53882.1 - 0.021 14.5 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) RVT_3 PF13456.1 OAP53883.1 - 0.0015 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Amidase PF01425.16 OAP53885.1 - 5.1e-26 91.5 5.6 6e-26 91.2 3.9 1.1 1 0 0 1 1 1 1 Amidase Voltage_CLC PF00654.15 OAP53886.1 - 0.2 10.6 2.2 0.13 11.2 0.3 1.6 2 0 0 2 2 2 0 Voltage gated chloride channel PDR_assoc PF08370.6 OAP53886.1 - 0.26 10.8 1.6 0.8 9.2 0.1 2.4 2 1 1 3 3 3 0 Plant PDR ABC transporter associated DUF914 PF06027.7 OAP53890.1 - 8.5e-26 90.5 4.0 1e-25 90.3 2.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) Zn_clus PF00172.13 OAP53894.1 - 0.021 14.7 1.3 0.032 14.1 0.9 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 OAP53894.1 - 0.052 13.4 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pox_F17 PF04767.7 OAP53894.1 - 0.065 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein FoP_duplication PF13865.1 OAP53897.1 - 8e-06 26.2 0.9 1.5e-05 25.3 0.6 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 AAA_11 PF13086.1 OAP53900.1 - 2.9e-07 30.3 0.0 5.7e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 OAP53900.1 - 0.00029 20.4 0.2 0.00043 19.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain DUF226 PF02890.9 OAP53900.1 - 0.0077 16.0 0.3 0.63 9.8 0.0 2.7 3 0 0 3 3 3 1 Borrelia family of unknown function DUF226 KaiC PF06745.8 OAP53900.1 - 0.038 13.1 0.0 0.1 11.7 0.0 1.6 1 1 0 1 1 1 0 KaiC AAA_19 PF13245.1 OAP53900.1 - 0.039 13.7 0.1 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 OAP53900.1 - 0.059 12.8 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cas_NE0113 PF09623.5 OAP53900.1 - 0.068 12.6 0.1 0.19 11.1 0.1 1.7 2 0 0 2 2 2 0 CRISPR-associated protein NE0113 (Cas_NE0113) AAA_22 PF13401.1 OAP53900.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain 3HCDH PF00725.17 OAP53904.1 - 0.073 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldh_1_C PF02866.13 OAP53906.1 - 0.0048 16.6 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Peptidase_M19 PF01244.16 OAP53908.1 - 4.6e-05 22.4 0.0 4.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) zf-C3HC4 PF00097.20 OAP53909.1 - 0.00014 21.4 11.2 0.00032 20.3 7.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP53909.1 - 0.0002 21.3 10.0 0.00058 19.8 6.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.6 OAP53909.1 - 0.00092 17.9 0.7 0.0012 17.5 0.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Cast PF10174.4 OAP53909.1 - 0.0014 16.7 0.4 0.0014 16.7 0.3 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone zf-C3HC4_3 PF13920.1 OAP53909.1 - 0.0019 17.8 10.2 0.0038 16.8 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.6 OAP53909.1 - 0.0099 15.7 4.5 0.016 15.0 3.1 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HlyD PF00529.15 OAP53909.1 - 0.011 15.0 0.9 0.014 14.6 0.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein AAA_13 PF13166.1 OAP53909.1 - 0.014 13.9 0.3 0.018 13.5 0.2 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 OAP53909.1 - 0.014 15.4 0.4 0.028 14.5 0.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC155 PF14662.1 OAP53909.1 - 0.017 14.7 0.4 0.022 14.3 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 zf-RING_5 PF14634.1 OAP53909.1 - 0.017 14.8 12.9 0.28 10.9 9.6 2.2 1 1 1 2 2 2 0 zinc-RING finger domain PspA_IM30 PF04012.7 OAP53909.1 - 0.023 14.0 2.8 0.03 13.6 2.0 1.3 1 0 0 1 1 1 0 PspA/IM30 family TACC PF05010.9 OAP53909.1 - 0.031 14.0 2.4 0.04 13.6 1.7 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) CENP-F_leu_zip PF10473.4 OAP53909.1 - 0.032 14.0 0.9 0.032 14.0 0.7 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 OAP53909.1 - 0.046 14.0 1.1 0.18 12.1 0.1 2.0 1 1 1 2 2 2 0 Snapin/Pallidin zf-RING_2 PF13639.1 OAP53909.1 - 0.048 13.4 12.8 0.084 12.7 8.9 1.4 1 0 0 1 1 1 0 Ring finger domain CorA PF01544.13 OAP53909.1 - 0.05 12.6 1.7 0.071 12.1 1.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C3HC4_4 PF15227.1 OAP53909.1 - 0.089 12.6 9.9 0.74 9.7 7.1 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING APG6 PF04111.7 OAP53909.1 - 0.098 11.6 1.5 0.18 10.8 1.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.9 OAP53909.1 - 0.12 12.0 1.1 0.18 11.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RRF_GI PF12614.3 OAP53909.1 - 0.13 12.0 3.2 0.22 11.3 2.2 1.3 1 0 0 1 1 1 0 Ribosome recycling factor zf-RING_UBOX PF13445.1 OAP53909.1 - 2 8.2 9.7 0.09 12.5 2.7 1.8 2 0 0 2 2 2 0 RING-type zinc-finger UDPGP PF01704.13 OAP53910.1 - 2.2e-82 276.8 0.3 9.6e-46 156.1 0.0 2.0 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase RsbRD_N PF14361.1 OAP53913.1 - 0.06 13.8 0.0 0.095 13.1 0.0 1.3 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Zn_clus PF00172.13 OAP53914.1 - 4.2e-07 29.7 13.5 7.7e-07 28.9 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2389 PF09493.5 OAP53915.1 - 0.1 12.8 0.2 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan-rich protein (DUF2389) DDE_3 PF13358.1 OAP53920.1 - 9e-08 31.9 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Thioredoxin PF00085.15 OAP53923.1 - 4e-06 26.4 0.0 5.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Oxygenase-NA PF09859.4 OAP53923.1 - 0.094 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA ASF1_hist_chap PF04729.8 OAP53926.1 - 1.4e-20 73.4 0.0 2.1e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone RNA_pol_I_A49 PF06870.7 OAP53926.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor zf-RING_4 PF14570.1 OAP53930.1 - 0.2 11.2 5.0 0.55 9.8 3.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4579 PF15158.1 OAP53931.1 - 0.087 12.3 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) DUF3910 PF13049.1 OAP53933.1 - 0.15 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) DUF1600 PF07667.6 OAP53937.1 - 5.6 7.0 7.2 33 4.6 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1600) RNA_pol_Rpb2_6 PF00562.23 OAP53943.1 - 4.5e-07 28.9 0.2 0.31 9.7 0.0 3.1 3 0 0 3 3 3 3 RNA polymerase Rpb2, domain 6 RVT_3 PF13456.1 OAP53947.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase-like WD40_alt PF14077.1 OAP53948.1 - 0.031 13.9 0.4 0.071 12.7 0.1 1.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif WEMBL PF05701.6 OAP53948.1 - 0.046 12.1 0.7 0.06 11.8 0.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 OAP53948.1 - 0.062 10.6 0.9 0.077 10.3 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec20 PF03908.8 OAP53948.1 - 0.14 11.9 0.2 0.27 10.9 0.2 1.4 1 0 0 1 1 1 0 Sec20 GAGA_bind PF06217.7 OAP53949.1 - 0.00025 21.1 0.4 0.0003 20.8 0.3 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family DUF4201 PF13870.1 OAP53949.1 - 0.024 14.0 0.3 0.024 14.0 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF972 PF06156.8 OAP53949.1 - 0.052 13.9 0.6 0.052 13.9 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) WEMBL PF05701.6 OAP53949.1 - 0.069 11.6 5.1 0.11 10.9 3.6 1.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Peptidase_S58 PF03576.9 OAP53949.1 - 0.1 11.7 0.4 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase family S58 IncA PF04156.9 OAP53949.1 - 0.31 10.6 3.0 0.32 10.5 1.7 1.5 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 OAP53949.1 - 3.9 6.3 7.8 1.7 7.5 1.0 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MIP-T3 PF10243.4 OAP53951.1 - 7.6 4.8 8.6 55 2.0 6.0 1.9 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 ImpE PF07024.8 OAP53952.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 ImpE protein Chromo PF00385.19 OAP53953.1 - 6.6e-08 32.1 0.7 2.1e-07 30.5 0.5 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDRGK PF09756.4 OAP53953.1 - 0.028 13.8 7.6 0.044 13.1 5.3 1.3 1 0 0 1 1 1 0 DDRGK domain Sec62 PF03839.11 OAP53953.1 - 0.38 10.1 4.2 0.61 9.4 2.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 NARP1 PF12569.3 OAP53953.1 - 0.9 8.2 10.7 0.89 8.2 6.4 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF4594 PF15266.1 OAP53957.1 - 0.25 11.4 4.0 11 6.0 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4594) RAB3GAP2_N PF14655.1 OAP53958.1 - 0.07 12.1 0.4 0.084 11.8 0.3 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus HMG_box PF00505.14 OAP53959.1 - 7.9e-21 74.1 0.2 1.4e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAP53959.1 - 3e-06 27.5 0.1 6.5e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 OAP53959.1 - 0.075 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 CHDNT (NUC034) domain Orbi_VP3 PF01700.11 OAP53966.1 - 0.0086 13.5 0.0 0.013 12.9 0.0 1.2 1 0 0 1 1 1 1 Orbivirus VP3 (T2) protein DUF2201_N PF13203.1 OAP53967.1 - 0.14 11.2 0.8 0.2 10.8 0.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Abhydrolase_3 PF07859.8 OAP53968.1 - 1.2e-05 24.9 0.0 2.6e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold GST_N PF02798.15 OAP53968.1 - 0.06 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Transp_cyt_pur PF02133.10 OAP53969.1 - 4.6e-11 41.9 0.2 4.6e-11 41.9 0.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MIP PF00230.15 OAP53969.1 - 0.077 12.4 0.1 0.091 12.2 0.1 1.1 1 0 0 1 1 1 0 Major intrinsic protein ABC_tran PF00005.22 OAP53972.1 - 4.2e-07 30.3 0.0 5.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.1 OAP53972.1 - 0.0012 18.6 0.0 0.0042 16.9 0.0 1.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Baculo_PEP_C PF04513.7 OAP53973.1 - 4.5e-06 26.5 2.0 1.1e-05 25.2 1.4 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 OAP53973.1 - 8.7e-06 24.5 0.6 1.1e-05 24.1 0.4 1.0 1 0 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 OAP53973.1 - 0.00039 19.7 0.1 0.00054 19.2 0.1 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Spc7 PF08317.6 OAP53973.1 - 0.0016 17.1 0.4 0.0022 16.7 0.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Transposase_22 PF02994.9 OAP53973.1 - 0.0032 16.0 1.2 0.0045 15.5 0.8 1.1 1 0 0 1 1 1 1 L1 transposable element Tht1 PF04163.7 OAP53973.1 - 0.011 14.2 0.6 0.014 13.8 0.4 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF2450 PF10475.4 OAP53973.1 - 0.013 14.3 0.3 0.02 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) TBPIP PF07106.8 OAP53973.1 - 0.021 14.3 0.3 0.032 13.7 0.2 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 OAP53973.1 - 0.033 14.0 6.2 0.8 9.6 0.5 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tektin PF03148.9 OAP53973.1 - 0.048 12.1 1.9 0.071 11.6 1.3 1.1 1 0 0 1 1 1 0 Tektin family WEMBL PF05701.6 OAP53973.1 - 0.051 12.0 0.1 0.067 11.6 0.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light AIP3 PF03915.8 OAP53973.1 - 0.056 12.3 0.5 0.076 11.9 0.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Allexi_40kDa PF05549.6 OAP53973.1 - 0.057 12.7 0.1 0.082 12.1 0.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Phage_Mu_Gam PF07352.7 OAP53973.1 - 0.058 12.9 2.0 0.27 10.7 0.0 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Filament PF00038.16 OAP53973.1 - 0.062 12.7 0.1 0.094 12.1 0.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein Apolipoprotein PF01442.13 OAP53973.1 - 0.064 12.7 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DivIC PF04977.10 OAP53973.1 - 0.089 12.2 1.1 2.3 7.7 0.0 2.5 1 1 0 2 2 2 0 Septum formation initiator Bacillus_HBL PF05791.6 OAP53973.1 - 0.13 11.6 3.2 0.13 11.6 1.2 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3375 PF11855.3 OAP53973.1 - 0.16 10.7 3.2 0.55 8.9 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3375) DUF1640 PF07798.6 OAP53973.1 - 0.2 11.6 2.7 2.7 7.9 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF1515 PF07439.6 OAP53973.1 - 0.25 11.1 2.9 0.52 10.1 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) SF-assemblin PF06705.6 OAP53973.1 - 0.29 10.2 5.6 0.57 9.2 3.9 1.4 1 1 0 1 1 1 0 SF-assemblin/beta giardin DUF1664 PF07889.7 OAP53973.1 - 0.3 10.8 10.7 0.22 11.3 4.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HsbA PF12296.3 OAP53973.1 - 0.35 10.7 7.9 0.66 9.8 3.7 2.3 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Syntaxin PF00804.20 OAP53973.1 - 0.37 10.9 7.6 1.5 9.0 5.2 2.1 1 1 0 1 1 1 0 Syntaxin Laminin_II PF06009.7 OAP53973.1 - 0.61 9.8 7.0 0.075 12.7 1.8 1.7 2 0 0 2 2 1 0 Laminin Domain II XhlA PF10779.4 OAP53973.1 - 0.81 9.6 9.0 0.78 9.6 4.4 2.3 1 1 1 2 2 2 0 Haemolysin XhlA NPV_P10 PF05531.7 OAP53973.1 - 1 9.6 9.6 14 6.0 6.2 2.6 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.6 OAP53973.1 - 1 6.7 4.4 0.13 9.7 0.4 1.4 2 0 0 2 2 2 0 Prominin Syntaxin_2 PF14523.1 OAP53973.1 - 1.7 8.7 6.5 36 4.4 0.3 2.9 1 1 1 2 2 2 0 Syntaxin-like protein Hemagglutinin PF00509.13 OAP53973.1 - 3.3 5.7 5.5 5 5.1 3.8 1.2 1 0 0 1 1 1 0 Haemagglutinin Halo_GVPC PF05465.8 OAP53973.1 - 3.6 7.6 6.2 33 4.5 0.3 3.5 3 1 1 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat CLP_protease PF00574.18 OAP53978.1 - 1.9e-42 144.9 0.0 2.3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Clp protease PBP_like PF12727.2 OAP53979.1 - 0.024 13.5 0.1 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain Peptidase_C48 PF02902.14 OAP53980.1 - 2e-05 24.3 0.1 5.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CHAT PF12770.2 OAP53981.1 - 3.1e-26 92.1 0.5 8.4e-26 90.7 0.4 1.7 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 OAP53981.1 - 3e-07 30.2 0.1 0.024 14.5 0.0 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat Peptidase_C25 PF01364.13 OAP53981.1 - 0.0046 15.9 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C25 TPR_14 PF13428.1 OAP53981.1 - 0.021 15.4 5.6 8.9 7.2 0.0 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.24 OAP53982.1 - 3e-11 43.1 0.0 3.4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase p450 PF00067.17 OAP53984.1 - 7.3e-12 44.5 0.0 8.6e-12 44.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3820 PF12843.2 OAP53984.1 - 0.011 15.3 0.1 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3820) ATP_bind_2 PF03668.10 OAP53984.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family Ipi1_N PF12333.3 OAP53986.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Aminotran_1_2 PF00155.16 OAP53989.1 - 3.8e-07 29.3 0.0 1.1e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3716 PF12511.3 OAP53992.1 - 3.1e-18 65.1 1.8 4.9e-18 64.4 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Methyltransf_23 PF13489.1 OAP53997.1 - 5.5e-18 65.1 0.0 7.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP53997.1 - 2.1e-08 34.7 0.0 2.3e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP53997.1 - 5e-08 32.6 0.0 1.7e-06 27.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP53997.1 - 0.00014 22.2 0.0 0.00029 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAP53997.1 - 0.0014 17.8 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 OAP53997.1 - 0.0031 17.9 0.0 0.034 14.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP53997.1 - 0.023 14.7 0.0 0.15 12.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 OAP53997.1 - 0.037 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 OAP53997.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 OAP53999.1 - 0.00066 19.3 0.5 0.00066 19.3 0.4 2.2 2 0 0 2 2 2 1 F-box-like DUF3669 PF12417.3 OAP54000.1 - 2.3e-19 68.8 0.3 7.4e-19 67.2 0.0 2.0 2 0 0 2 2 2 1 Zinc finger protein F-box PF00646.28 OAP54002.1 - 0.00094 18.7 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP54002.1 - 0.0031 17.2 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like TctB PF07331.6 OAP54005.1 - 0.0084 15.7 0.0 0.0088 15.7 0.0 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF4534 PF15049.1 OAP54005.1 - 0.017 14.7 1.4 0.019 14.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) Kelch_4 PF13418.1 OAP54006.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain DUF919 PF06034.6 OAP54006.1 - 0.15 11.7 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) OsmC PF02566.14 OAP54008.1 - 0.11 12.6 0.5 0.37 10.9 0.4 1.8 1 0 0 1 1 1 0 OsmC-like protein Zn_clus PF00172.13 OAP54008.1 - 0.4 10.6 2.0 0.43 10.5 0.2 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EMP24_GP25L PF01105.19 OAP54008.1 - 0.52 9.9 4.9 1.5 8.4 3.3 1.9 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD OmpH PF03938.9 OAP54008.1 - 0.57 10.1 16.6 0.43 10.4 4.8 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Vps51 PF08700.6 OAP54008.1 - 0.82 9.5 4.3 15 5.5 0.1 2.7 2 0 0 2 2 2 0 Vps51/Vps67 UPF0449 PF15136.1 OAP54008.1 - 5.1 7.3 7.9 2.8 8.2 0.4 2.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 F-box-like PF12937.2 OAP54009.1 - 0.0018 17.9 0.0 0.0056 16.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 OAP54011.1 - 7.2e-23 81.0 0.0 8.7e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54011.1 - 7.6e-09 35.0 0.1 8.9e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP54011.1 - 0.0058 16.3 0.3 0.028 14.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP54011.1 - 0.033 13.7 0.0 0.087 12.3 0.0 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Cytochrome_C7 PF14522.1 OAP54013.1 - 0.0024 17.4 0.3 0.0024 17.4 0.2 2.7 2 1 0 3 3 3 1 Cytochrome c7 Cytochrome_C554 PF13435.1 OAP54013.1 - 0.0028 17.6 3.8 0.036 14.1 0.4 2.5 1 1 1 2 2 2 2 Cytochrome c554 and c-prime F-box-like PF12937.2 OAP54013.1 - 0.0056 16.3 0.0 0.041 13.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like Cytochrom_c3_2 PF14537.1 OAP54013.1 - 0.009 16.3 0.1 0.009 16.3 0.0 2.4 4 0 0 4 4 4 1 Cytochrome c3 zf-C3HC4 PF00097.20 OAP54014.1 - 0.00014 21.4 12.7 0.00025 20.6 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP54014.1 - 0.00031 20.7 13.7 0.00051 20.0 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP54014.1 - 0.0005 19.8 13.3 0.00085 19.0 9.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAP54014.1 - 0.011 15.4 12.7 0.045 13.4 9.0 1.9 1 1 1 2 2 2 0 zinc-RING finger domain DUF677 PF05055.7 OAP54014.1 - 0.032 12.9 1.3 0.042 12.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) zf-C3HC4_4 PF15227.1 OAP54014.1 - 0.048 13.5 12.5 0.44 10.4 8.9 2.4 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING CENP-F_leu_zip PF10473.4 OAP54014.1 - 0.062 13.1 5.2 0.097 12.5 3.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-rbx1 PF12678.2 OAP54014.1 - 0.22 11.6 8.6 0.48 10.5 5.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger SlyX PF04102.7 OAP54014.1 - 0.48 10.8 3.3 1.2 9.6 0.2 2.3 1 1 1 2 2 2 0 SlyX TMF_DNA_bd PF12329.3 OAP54014.1 - 0.51 10.1 5.8 0.11 12.3 0.4 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TBCA PF02970.11 OAP54014.1 - 0.75 9.9 5.0 1.2 9.2 3.5 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A VASP_tetra PF08776.6 OAP54019.1 - 2.7 7.3 4.9 1.5 8.1 1.2 2.1 2 0 0 2 2 2 0 VASP tetramerisation domain Pkinase PF00069.20 OAP54020.1 - 4.1e-46 157.2 0.0 5.9e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54020.1 - 1.2e-23 83.5 0.0 1.9e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 OAP54020.1 - 0.0013 18.7 0.1 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 OAP54020.1 - 0.027 13.5 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NDT80_PhoG PF05224.7 OAP54022.1 - 4.2e-11 43.1 0.0 7.1e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ABC_tran PF00005.22 OAP54023.1 - 2.3e-08 34.4 0.0 3.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.1 OAP54023.1 - 0.032 14.1 1.1 0.62 10.0 0.8 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF1479 PF07350.7 OAP54024.1 - 1.3e-05 23.8 0.0 1.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Peptidase_S64 PF08192.6 OAP54025.1 - 3.7e-07 28.9 0.0 5.3e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S3 PF00944.14 OAP54025.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Alphavirus core protein Trypsin_2 PF13365.1 OAP54025.1 - 0.0086 16.0 0.0 0.022 14.7 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 OAP54025.1 - 0.027 13.4 0.4 0.042 12.8 0.3 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 OAP54025.1 - 0.05 12.0 0.1 0.083 11.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase S46 Trypsin PF00089.21 OAP54025.1 - 0.054 13.0 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Trypsin DUF3819 PF12842.2 OAP54026.1 - 0.19 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Elf1 PF05129.8 OAP54027.1 - 1.7e-20 72.4 3.3 1.9e-20 72.3 0.1 2.5 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Phage_gp53 PF11246.3 OAP54027.1 - 0.045 13.1 0.2 0.082 12.3 0.2 1.4 1 0 0 1 1 1 0 Base plate wedge protein 53 SpoOE-like PF09388.5 OAP54027.1 - 0.65 9.5 2.8 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein DUF2863 PF11062.3 OAP54028.1 - 0.13 10.3 0.1 0.19 9.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Zn_clus PF00172.13 OAP54030.1 - 3.8e-06 26.7 11.0 7.1e-06 25.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNH_2 PF13391.1 OAP54031.1 - 1.9e-06 27.5 0.0 4.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF3584 PF12128.3 OAP54031.1 - 2.5 5.3 37.3 0.4 7.9 16.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) OTT_1508_deam PF14441.1 OAP54033.1 - 0.00038 20.2 0.2 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 OTT_1508-like deaminase HNH_2 PF13391.1 OAP54034.1 - 0.0001 21.9 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease IncA PF04156.9 OAP54034.1 - 0.23 11.0 26.2 0.014 15.0 7.2 2.5 2 0 0 2 2 2 0 IncA protein DUF4158 PF13700.1 OAP54035.1 - 0.028 13.9 0.0 0.032 13.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) zf-RanBP PF00641.13 OAP54039.1 - 0.0052 15.8 3.3 0.009 15.0 2.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PP-binding PF00550.20 OAP54042.1 - 6.4e-10 39.1 0.1 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site HEAT PF02985.17 OAP54042.1 - 7.7e-07 28.6 0.9 0.016 15.2 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 OAP54042.1 - 3.1e-06 27.3 0.2 0.0028 17.8 0.0 2.4 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 OAP54042.1 - 5.5e-05 23.5 0.4 0.063 13.7 0.1 2.8 2 1 1 3 3 3 2 HEAT-like repeat Arm PF00514.18 OAP54042.1 - 0.00081 19.1 0.4 2.6 8.0 0.1 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 OAP54042.1 - 0.0015 17.9 0.1 0.0027 17.1 0.1 1.5 1 1 0 1 1 1 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 OAP54042.1 - 0.034 14.5 0.0 1.6 9.1 0.0 2.3 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 OAP54042.1 - 0.038 12.7 0.9 0.17 10.5 0.2 1.8 1 1 0 2 2 2 0 RNAPII transcription regulator C-terminal RIX1 PF08167.7 OAP54042.1 - 0.062 12.9 0.1 0.2 11.3 0.0 2.0 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis SPC25 PF06703.6 OAP54043.1 - 2.1e-20 72.9 0.1 2.5e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Adaptin_N PF01602.15 OAP54044.1 - 5.3e-07 28.3 0.0 5.8e-07 28.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF975 PF06161.6 OAP54044.1 - 0.084 12.5 0.2 0.096 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF975) Selenoprotein_S PF06936.6 OAP54046.1 - 0.0051 16.3 0.2 0.0077 15.7 0.1 1.2 1 0 0 1 1 1 1 Selenoprotein S (SelS) DUF4381 PF14316.1 OAP54046.1 - 0.0069 16.5 0.2 0.011 15.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) ABC_membrane PF00664.18 OAP54046.1 - 0.046 13.1 2.0 0.062 12.7 1.4 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF1816 PF08846.5 OAP54046.1 - 0.092 12.4 0.2 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) SET PF00856.23 OAP54048.1 - 2e-14 54.1 2.4 7.6e-13 49.0 0.3 2.7 2 1 0 2 2 2 1 SET domain Peptidase_S64 PF08192.6 OAP54049.1 - 0.0025 16.2 0.3 0.2 9.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 Trypsin_2 PF13365.1 OAP54049.1 - 0.046 13.6 0.1 0.57 10.1 0.0 2.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain Histone PF00125.19 OAP54050.1 - 1.1e-27 95.9 0.1 2e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAP54050.1 - 1e-06 28.8 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAP54050.1 - 0.0044 17.0 0.0 0.0096 15.9 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 OAP54050.1 - 0.015 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 OAP54050.1 - 0.11 11.7 0.2 0.21 10.8 0.1 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Abhydrolase_3 PF07859.8 OAP54053.1 - 5.1e-07 29.4 0.0 8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold NADH_4Fe-4S PF10589.4 OAP54054.1 - 0.067 12.3 0.4 0.15 11.2 0.3 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region BBE PF08031.7 OAP54055.1 - 0.0014 18.4 0.5 0.0026 17.6 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like CDC45 PF02724.9 OAP54057.1 - 0.15 10.0 6.2 0.15 10.0 4.3 1.0 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 OAP54057.1 - 0.29 9.4 4.3 0.33 9.3 3.0 1.1 1 0 0 1 1 1 0 Hsp90 protein Daxx PF03344.10 OAP54057.1 - 0.95 7.8 12.5 1 7.7 8.7 1.0 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 OAP54057.1 - 1.6 7.6 6.3 1.9 7.4 4.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.6 OAP54057.1 - 3.2 5.7 6.1 3.6 5.5 4.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 OAP54057.1 - 4.9 6.3 12.8 5.6 6.1 8.9 1.0 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 OAP54057.1 - 7.3 5.5 11.6 8.1 5.3 8.1 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 OAP54057.1 - 8 4.2 15.7 9.4 4.0 10.9 1.0 1 0 0 1 1 1 0 Nop14-like family PPV_E1_N PF00524.13 OAP54059.1 - 0.035 14.3 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 E1 Protein, N terminal domain p450 PF00067.17 OAP54060.1 - 0.032 12.7 0.0 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 Activator_LAG-3 PF11498.3 OAP54062.1 - 0.36 9.5 72.5 0.69 8.5 50.3 1.6 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Transcrip_reg PF01709.15 OAP54063.1 - 4e-07 29.3 1.5 5.8e-07 28.8 1.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator DUF3842 PF12953.2 OAP54063.1 - 0.088 12.9 0.2 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) UBA PF00627.26 OAP54068.1 - 0.1 12.5 0.3 0.3 10.9 0.0 1.9 1 1 1 2 2 2 0 UBA/TS-N domain Imm2 PF14426.1 OAP54075.1 - 0.11 12.4 0.0 35 4.5 0.0 3.2 3 0 0 3 3 3 0 Immunity protein Imm2 FCD PF07729.7 OAP54075.1 - 8.3 6.7 8.9 1.3 9.3 0.9 2.5 1 1 1 2 2 2 0 FCD domain AAA_12 PF13087.1 OAP54077.1 - 4.8e-16 58.7 0.0 5.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Herpes_BLLF1 PF05109.8 OAP54077.1 - 0.27 9.1 1.0 0.36 8.7 0.7 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Homeobox PF00046.24 OAP54078.1 - 4.3e-10 39.0 0.2 7.6e-10 38.2 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain EFG_II PF14492.1 OAP54078.1 - 0.11 12.3 0.1 0.29 10.9 0.1 1.7 2 0 0 2 2 2 0 Elongation Factor G, domain II Dispanin PF04505.7 OAP54079.1 - 0.06 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Halo_GVPC PF05465.8 OAP54080.1 - 0.0047 16.8 0.4 3.5 7.6 0.0 2.5 2 0 0 2 2 2 2 Halobacterial gas vesicle protein C (GVPC) repeat IL12 PF03039.9 OAP54080.1 - 0.061 12.4 0.0 5 6.1 0.0 2.0 2 0 0 2 2 2 0 Interleukin-12 alpha subunit Med26 PF08711.6 OAP54082.1 - 0.00038 19.8 0.2 0.00077 18.9 0.2 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Oxysterol_BP PF01237.13 OAP54084.1 - 6.5e-06 24.8 0.0 1.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein NESP55 PF06390.7 OAP54084.1 - 0.06 12.7 1.0 0.097 12.0 0.7 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Dynamin_N PF00350.18 OAP54089.1 - 0.00084 19.1 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin family DUF726 PF05277.7 OAP54091.1 - 0.0017 17.2 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Mito_fiss_reg PF05308.6 OAP54092.1 - 0.0022 17.4 1.5 0.0035 16.7 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator adh_short PF00106.20 OAP54092.1 - 0.011 15.6 0.1 0.037 13.9 0.0 1.8 1 1 1 2 2 2 0 short chain dehydrogenase Glyco_transf_5 PF08323.6 OAP54092.1 - 0.099 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain CAP_N PF01213.14 OAP54092.1 - 2.2 7.4 6.3 3.4 6.8 4.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal JmjC PF02373.17 OAP54093.1 - 2e-16 60.2 0.0 4.7e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.23 OAP54093.1 - 0.026 14.8 0.9 0.078 13.2 0.0 2.3 3 0 0 3 3 3 0 SET domain Trypan_PARP PF05887.6 OAP54093.1 - 0.049 13.4 0.2 0.049 13.4 0.1 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) APG17 PF04108.7 OAP54096.1 - 0.00058 18.7 0.1 0.001 17.9 0.1 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 Inositol_P PF00459.20 OAP54097.1 - 2.4e-18 66.4 0.0 3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family HET PF06985.6 OAP54100.1 - 0.012 15.8 0.7 0.29 11.2 0.5 2.5 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) eIF-3c_N PF05470.7 OAP54104.1 - 0.36 8.8 7.3 0.16 9.9 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RCC_reductase PF06405.6 OAP54106.1 - 0.022 13.7 0.0 3.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Red chlorophyll catabolite reductase (RCC reductase) Arginase PF00491.16 OAP54110.1 - 1.2e-09 37.8 0.1 1.5e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Arginase family Rad60-SLD PF11976.3 OAP54111.1 - 9.4e-21 73.2 0.2 1.2e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAP54111.1 - 9.5e-06 24.9 0.1 1.2e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family zf-CCHC_2 PF13696.1 OAP54112.1 - 7.5e-07 28.5 0.7 1.6e-06 27.4 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAP54112.1 - 0.0014 18.4 4.8 0.0023 17.7 3.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Enolase_N PF03952.11 OAP54115.1 - 1.7e-10 40.9 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain HNH_2 PF13391.1 OAP54115.1 - 2.6e-08 33.5 0.1 4.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease PAH PF02671.16 OAP54117.1 - 4.2e-11 42.2 0.0 6.3e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat YppG PF14179.1 OAP54117.1 - 0.16 12.6 9.0 0.22 12.1 6.3 1.4 1 0 0 1 1 1 0 YppG-like protein DUF4106 PF13388.1 OAP54117.1 - 0.39 9.6 5.2 0.48 9.3 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Trypsin_2 PF13365.1 OAP54118.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain HNH_2 PF13391.1 OAP54119.1 - 6.5e-06 25.8 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease EST1_DNA_bind PF10373.4 OAP54120.1 - 2.1e-07 30.4 0.0 3.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Histone PF00125.19 OAP54121.1 - 0.051 13.6 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF2526 PF10735.4 OAP54121.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Opi1 PF08618.5 OAP54123.1 - 7.6e-06 25.1 0.2 3.4e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Transcription factor Opi1 F-box PF00646.28 OAP54124.1 - 0.0013 18.3 1.6 0.0016 18.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 OAP54124.1 - 5.3 6.8 10.4 0.42 10.3 1.4 3.2 4 1 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 OAP54124.1 - 6.7 6.4 10.8 43 3.8 0.0 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Dodecin PF07311.7 OAP54127.1 - 0.074 13.0 0.2 0.074 13.0 0.1 2.2 3 0 0 3 3 3 0 Dodecin Baculo_PEP_C PF04513.7 OAP54127.1 - 0.23 11.3 6.9 0.17 11.6 2.8 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHC_N2 PF08393.8 OAP54127.1 - 0.63 8.4 3.9 0.29 9.6 0.7 1.7 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 Reo_sigmaC PF04582.7 OAP54127.1 - 0.78 8.8 5.7 0.32 10.1 1.6 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein F-box PF00646.28 OAP54128.1 - 0.00043 19.8 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP54128.1 - 0.0029 17.2 0.0 0.006 16.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like Baculo_DNA_bind PF04786.7 OAP54129.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein His_kinase PF06580.8 OAP54129.1 - 0.13 12.1 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Histidine kinase Inhibitor_I71 PF12628.2 OAP54129.1 - 0.16 11.6 0.4 0.19 11.3 0.3 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Herpes_UL25 PF01499.11 OAP54129.1 - 0.25 9.6 2.7 0.27 9.4 1.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3435 PF11917.3 OAP54129.1 - 0.27 9.9 3.5 0.31 9.6 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Med19 PF10278.4 OAP54129.1 - 0.98 9.0 7.1 1.1 8.8 4.9 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Hep_59 PF07052.6 OAP54130.1 - 0.017 15.4 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 DUF4603 PF15376.1 OAP54130.1 - 0.19 8.8 1.0 0.23 8.6 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Pacs-1 PF10254.4 OAP54130.1 - 0.29 9.7 3.4 0.37 9.3 2.4 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein FAD_binding_4 PF01565.18 OAP54131.1 - 1.2e-25 89.5 0.0 1.7e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain zf-C2H2_4 PF13894.1 OAP54135.1 - 8.2e-06 25.7 8.9 0.14 12.5 0.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP54135.1 - 0.0034 17.6 11.8 0.43 11.0 1.0 3.7 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP54135.1 - 0.24 11.7 12.5 1.3 9.4 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double domain UQ_con PF00179.21 OAP54136.1 - 6.6e-49 164.9 0.0 7.5e-49 164.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP54136.1 - 3.9e-05 23.4 0.0 4.4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAP54136.1 - 0.007 16.2 0.1 0.012 15.4 0.1 1.6 1 1 0 1 1 1 1 RWD domain RVT_1 PF00078.22 OAP54137.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4172 PF13776.1 OAP54139.1 - 0.04 13.9 0.2 0.54 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) OapA_N PF08525.6 OAP54139.1 - 0.076 12.7 0.5 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif CCDC-167 PF15188.1 OAP54141.1 - 0.045 13.7 0.4 0.059 13.3 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spore_II_R PF09551.5 OAP54141.1 - 0.24 11.4 1.6 0.3 11.1 1.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) NUT_C PF12882.2 OAP54144.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 NUT protein C terminal HNH_2 PF13391.1 OAP54146.1 - 0.00015 21.4 0.0 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 1 HNH endonuclease Abhydrolase_3 PF07859.8 OAP54147.1 - 7.2e-05 22.4 0.0 8.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cation_ATPase_C PF00689.16 OAP54149.1 - 0.00083 18.9 0.1 0.001 18.6 0.1 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus FliM PF02154.10 OAP54151.1 - 2.1e-07 30.8 0.6 0.4 10.3 0.0 3.1 1 1 2 3 3 3 3 Flagellar motor switch protein FliM DUF349 PF03993.7 OAP54151.1 - 3.7e-07 30.2 0.2 0.82 9.8 0.0 3.3 3 0 0 3 3 3 3 Domain of Unknown Function (DUF349) RPW8 PF05659.6 OAP54151.1 - 5.9e-05 22.6 0.1 2.5 7.6 0.0 3.1 1 1 2 3 3 3 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 BBS2_C PF14782.1 OAP54151.1 - 0.00023 19.8 0.1 0.26 9.8 0.0 2.2 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal Telomere_reg-2 PF10193.4 OAP54151.1 - 0.00026 21.2 0.1 2.3 8.5 0.1 3.4 2 1 0 2 2 2 1 Telomere length regulation protein DUF1858 PF08984.6 OAP54151.1 - 0.00055 19.5 0.1 7.6 6.2 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1858) Globin PF00042.17 OAP54151.1 - 0.0055 17.0 0.0 9.6 6.5 0.0 3.2 1 1 2 3 3 3 0 Globin DNA_circ_N PF07157.7 OAP54151.1 - 0.0061 16.6 0.2 18 5.5 0.0 3.2 2 1 1 3 3 3 0 DNA circularisation protein N-terminus UBN2 PF14223.1 OAP54151.1 - 0.0086 15.8 0.0 17 5.2 0.0 3.1 1 1 2 3 3 3 0 gag-polypeptide of LTR copia-type ArsR PF09824.4 OAP54151.1 - 0.011 15.0 0.7 8 5.7 0.0 3.4 1 1 3 4 4 4 0 ArsR transcriptional regulator DUF2218 PF09981.4 OAP54151.1 - 0.017 15.3 0.3 29 4.9 0.1 3.1 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) GLTP PF08718.6 OAP54151.1 - 0.024 14.6 0.0 24 4.9 0.0 3.1 3 0 0 3 3 3 0 Glycolipid transfer protein (GLTP) PsbK PF02533.10 OAP54151.1 - 0.024 14.5 0.0 55 3.8 0.0 3.2 3 0 0 3 3 3 0 Photosystem II 4 kDa reaction centre component Toxin_51 PF15531.1 OAP54151.1 - 0.028 14.2 0.1 32 4.3 0.0 3.5 2 1 2 4 4 4 0 Putative toxin 51 2_5_RNA_ligase2 PF13563.1 OAP54151.1 - 0.14 11.8 0.0 8.3 6.1 0.0 2.2 1 1 2 3 3 3 0 2'-5' RNA ligase superfamily F-112 PF09645.5 OAP54151.1 - 0.15 11.9 0.6 33 4.4 0.0 3.1 1 1 2 3 3 3 0 F-112 protein Chromo PF00385.19 OAP54155.1 - 0.00011 21.8 0.3 0.0002 20.9 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SelB-wing_2 PF09106.6 OAP54155.1 - 0.005 16.7 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor SelB, winged helix CheD PF03975.8 OAP54156.1 - 0.086 12.6 0.4 0.51 10.1 0.0 2.3 3 0 0 3 3 3 0 CheD chemotactic sensory transduction IMD PF08397.6 OAP54157.1 - 0.14 11.4 0.4 4.8 6.4 0.1 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain FAST_1 PF06743.10 OAP54158.1 - 0.084 12.5 0.5 5.1 6.8 0.0 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 NDT80_PhoG PF05224.7 OAP54160.1 - 3e-26 92.5 0.0 3.5e-25 89.0 0.0 2.1 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family UIM PF02809.15 OAP54161.1 - 0.0055 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif Zn_clus PF00172.13 OAP54165.1 - 3.7e-08 33.1 9.2 5.7e-08 32.5 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 OAP54165.1 - 3.5 7.8 14.0 5.1 7.3 1.9 2.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Ras PF00071.17 OAP54166.1 - 3.7e-07 29.6 0.0 3.8e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP54166.1 - 0.037 14.5 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein HNH_2 PF13391.1 OAP54172.1 - 8.2e-07 28.7 0.0 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Ank_2 PF12796.2 OAP54173.1 - 3.4e-07 30.5 0.0 3.5e-06 27.2 0.0 1.8 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP54173.1 - 4.1e-06 27.1 0.2 0.0007 20.0 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 OAP54173.1 - 1.3e-05 24.7 0.0 0.14 12.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAP54173.1 - 0.00046 20.1 0.1 0.077 13.2 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 OAP54173.1 - 0.0081 16.3 0.1 0.78 10.0 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) FAD_binding_2 PF00890.19 OAP54175.1 - 0.027 13.3 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain PWWP PF00855.12 OAP54176.1 - 2.3e-11 43.7 0.0 2.3e-11 43.7 0.0 2.4 3 1 0 3 3 3 1 PWWP domain DUF2935 PF11155.3 OAP54176.1 - 0.012 15.6 0.2 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) TFIIA PF03153.8 OAP54176.1 - 2.6 7.8 21.5 0.071 13.0 3.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UvrC_HhH_N PF08459.6 OAP54178.1 - 0.012 15.1 0.2 0.62 9.5 0.0 2.0 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal zf-C2H2_jaz PF12171.3 OAP54182.1 - 0.00018 21.5 0.1 0.00044 20.2 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 OAP54182.1 - 0.0043 17.2 0.2 0.01 16.1 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C3HC PF07967.8 OAP54182.1 - 0.0062 16.2 0.3 0.018 14.8 0.2 1.7 1 0 0 1 1 1 1 C3HC zinc finger-like zf-C2H2_4 PF13894.1 OAP54182.1 - 0.012 15.9 0.3 0.029 14.6 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 OAP54182.1 - 0.017 15.2 0.3 0.039 14.1 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Anoctamin PF04547.7 OAP54186.1 - 0.00044 19.0 0.0 0.00053 18.7 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel HNH_2 PF13391.1 OAP54188.1 - 2.3e-09 36.9 0.0 5.5e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease VWA PF00092.23 OAP54189.1 - 0.038 13.7 0.0 0.051 13.2 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain Amidase PF01425.16 OAP54190.1 - 0.0087 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Amidase p450 PF00067.17 OAP54193.1 - 5.1e-06 25.2 0.0 6.5e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3723 PF12520.3 OAP54194.1 - 0.012 14.0 0.1 0.014 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) IMPDH PF00478.20 OAP54195.1 - 7.8e-10 38.1 2.7 6.8e-08 31.7 1.9 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain MCM PF00493.18 OAP54195.1 - 0.1 11.3 0.2 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 MCM2/3/5 family Inositol_P PF00459.20 OAP54197.1 - 9.5e-20 71.0 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M20 PF01546.23 OAP54197.1 - 0.035 13.6 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ATP-synt PF00231.14 OAP54198.1 - 2.7e-11 43.3 0.6 3e-11 43.1 0.4 1.0 1 0 0 1 1 1 1 ATP synthase ERp29 PF07749.7 OAP54201.1 - 0.069 13.7 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain FAD_binding_3 PF01494.14 OAP54202.1 - 0.0017 17.4 0.3 0.0024 16.9 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain zf-Mss51 PF13824.1 OAP54203.1 - 2.2e-06 27.4 0.5 3.9e-06 26.6 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Poty_PP PF08440.5 OAP54204.1 - 0.056 12.4 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein HET PF06985.6 OAP54205.1 - 0.014 15.5 0.4 0.024 14.8 0.2 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) NOA36 PF06524.7 OAP54207.1 - 2.6 7.2 4.9 3.3 6.8 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 OAP54207.1 - 5.3 5.6 11.5 8 5.0 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rpr2 PF04032.11 OAP54210.1 - 0.086 12.7 3.5 0.23 11.3 2.4 1.7 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain LexA_DNA_bind PF01726.11 OAP54210.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 LexA DNA binding domain zinc_ribbon_2 PF13240.1 OAP54210.1 - 0.19 11.2 2.5 0.36 10.3 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain MAD PF05557.8 OAP54212.1 - 6.4e-06 24.5 0.0 6.6e-06 24.5 0.0 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Herpes_BLLF1 PF05109.8 OAP54213.1 - 0.21 9.5 5.9 0.22 9.4 4.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DNA_pol_B PF00136.16 OAP54214.1 - 2.5e-22 79.3 0.7 4.2e-22 78.5 0.5 1.3 1 1 0 1 1 1 1 DNA polymerase family B PBP-Tp47_c PF14888.1 OAP54214.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain C DUF349 PF03993.7 OAP54215.1 - 6.6e-08 32.6 0.5 0.16 12.1 0.0 3.1 1 1 2 3 3 3 3 Domain of Unknown Function (DUF349) GLTP PF08718.6 OAP54215.1 - 4.4e-05 23.5 0.1 1.6 8.7 0.0 3.0 1 1 2 3 3 3 2 Glycolipid transfer protein (GLTP) Toxin_51 PF15531.1 OAP54215.1 - 0.0043 16.8 0.0 16 5.3 0.0 3.0 1 1 2 3 3 3 0 Putative toxin 51 THF_DHG_CYH_C PF02882.14 OAP54215.1 - 0.0048 15.9 0.4 0.84 8.6 0.0 2.6 2 1 1 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Terminase_4 PF05119.7 OAP54215.1 - 0.007 16.5 0.2 2.3 8.4 0.0 2.6 1 1 2 3 3 3 2 Phage terminase, small subunit FliM PF02154.10 OAP54215.1 - 0.0078 15.8 0.4 4.4 6.9 0.0 3.0 1 1 2 3 3 3 1 Flagellar motor switch protein FliM DUF4363 PF14276.1 OAP54215.1 - 0.0093 15.6 1.3 5.8 6.6 0.0 2.9 1 1 2 3 3 3 2 Domain of unknown function (DUF4363) LdpA_C PF12617.3 OAP54215.1 - 0.0098 15.1 0.2 4.1 6.6 0.0 2.5 1 1 1 2 2 2 2 Iron-Sulfur binding protein C terminal DHC_N2 PF08393.8 OAP54215.1 - 0.011 14.3 1.1 0.43 9.0 0.1 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 2 HhH-GPD PF00730.20 OAP54215.1 - 0.011 15.9 0.7 4 7.7 0.1 2.9 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein DUF1572 PF07609.6 OAP54215.1 - 0.024 14.1 0.2 3.5 7.1 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1572) UBN2 PF14223.1 OAP54215.1 - 0.024 14.3 0.1 6.2 6.6 0.0 2.6 1 1 2 3 3 3 0 gag-polypeptide of LTR copia-type Phage_int_SAM_3 PF14659.1 OAP54215.1 - 0.035 14.3 1.3 4.1 7.7 0.0 3.0 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain YrpD PF15493.1 OAP54215.1 - 0.039 13.5 0.3 0.063 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function, YrpD MKT1_C PF12246.3 OAP54215.1 - 0.065 12.2 1.6 1.3 8.0 0.3 2.3 1 1 1 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication FliD_N PF02465.13 OAP54215.1 - 0.083 13.2 0.0 1.2 9.5 0.0 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus F-112 PF09645.5 OAP54215.1 - 0.088 12.6 1.2 3.4 7.6 0.1 2.3 1 1 0 2 2 2 0 F-112 protein AIP3 PF03915.8 OAP54216.1 - 3.4e-144 480.8 16.2 3.4e-144 480.8 11.2 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.9 OAP54216.1 - 0.021 14.1 0.3 0.096 12.0 0.2 2.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain LPP PF04728.8 OAP54216.1 - 0.091 12.5 4.9 0.29 10.9 0.5 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.6 OAP54216.1 - 0.094 12.5 13.0 0.34 10.7 1.4 4.5 4 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) K_channel_TID PF07941.6 OAP54216.1 - 1.9 8.7 16.7 0.49 10.6 5.4 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF1664 PF07889.7 OAP54216.1 - 6.2 6.6 12.0 6.9 6.4 0.3 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.1 OAP54216.1 - 9.6 6.3 11.5 3.6 7.6 0.0 4.1 3 1 1 4 4 4 0 Syntaxin-like protein Nop52 PF05997.7 OAP54217.1 - 1e-29 103.5 0.0 8.1e-29 100.5 0.0 1.9 1 1 0 1 1 1 1 Nucleolar protein,Nop52 DUF1295 PF06966.7 OAP54218.1 - 6.2e-37 127.1 8.0 8.9e-37 126.6 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PAS_9 PF13426.1 OAP54218.1 - 2.4e-21 76.0 0.0 1.1e-18 67.4 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 OAP54218.1 - 0.0003 20.5 0.0 0.00092 18.9 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 OAP54218.1 - 0.0056 16.7 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold DUF2517 PF10725.4 OAP54218.1 - 0.1 12.2 0.5 0.69 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) ICMT PF04140.9 OAP54218.1 - 0.11 12.7 0.6 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.15 OAP54219.1 - 1.2e-94 317.4 0.0 1.5e-94 317.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 OAP54219.1 - 9.7e-18 63.9 0.0 3.2e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Toprim domain SE PF08491.5 OAP54219.1 - 0.072 11.8 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DUF2985 PF11204.3 OAP54221.1 - 7.4e-35 118.5 1.3 7.4e-35 118.5 0.9 1.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2985) Lig_chan PF00060.21 OAP54221.1 - 0.4 10.3 0.0 0.4 10.3 0.0 2.5 2 1 0 2 2 2 0 Ligand-gated ion channel Sen15 PF09631.5 OAP54222.1 - 6.7e-14 51.9 0.0 0.00032 20.8 0.0 3.3 3 0 0 3 3 3 3 Sen15 protein Vac_ImportDeg PF09783.4 OAP54223.1 - 2.4e-63 212.8 1.5 7e-63 211.3 1.2 1.6 2 0 0 2 2 2 1 Vacuolar import and degradation protein ubiquitin PF00240.18 OAP54223.1 - 0.00018 20.8 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 OAP54223.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Mago_nashi PF02792.9 OAP54224.1 - 6e-67 223.7 3.1 7.2e-65 217.0 2.1 2.1 1 1 0 1 1 1 1 Mago nashi protein NMT1 PF09084.6 OAP54225.1 - 1.2e-05 25.0 0.0 0.00012 21.7 0.0 2.2 2 1 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.15 OAP54225.1 - 0.00027 20.2 0.0 0.00069 18.9 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 OAP54225.1 - 0.0021 17.4 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.11 OAP54226.1 - 1.7e-37 128.9 24.3 1.7e-37 128.9 16.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP54226.1 - 3.4e-06 25.5 3.2 5.9e-06 24.7 2.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 OAP54226.1 - 0.11 10.4 16.5 0.073 11.1 0.8 3.3 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family zf-DHHC PF01529.15 OAP54226.1 - 0.75 9.1 3.5 3.4 7.0 2.4 2.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase FAD_binding_3 PF01494.14 OAP54227.1 - 5.9e-21 74.9 0.0 8.9e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP54227.1 - 2.8e-05 23.1 1.7 0.011 14.6 0.2 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 OAP54227.1 - 0.00037 19.4 0.0 0.0012 17.7 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 OAP54227.1 - 0.0012 18.7 0.5 0.0024 17.7 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP54227.1 - 0.0015 17.0 1.1 0.0027 16.2 0.7 1.3 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 OAP54227.1 - 0.0017 18.3 1.5 0.02 14.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP54227.1 - 0.0042 16.8 0.9 0.049 13.3 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding MutL PF13941.1 OAP54227.1 - 0.035 12.4 0.0 0.059 11.6 0.0 1.2 1 0 0 1 1 1 0 MutL protein ADH_zinc_N PF00107.21 OAP54228.1 - 7.4e-24 83.7 0.1 1.3e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP54228.1 - 1.5e-21 76.1 0.8 2.4e-21 75.5 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ThiF PF00899.16 OAP54228.1 - 0.29 10.9 1.7 0.33 10.7 0.3 1.7 2 0 0 2 2 2 0 ThiF family p450 PF00067.17 OAP54230.1 - 1.3e-19 70.1 0.0 2.2e-18 66.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 OAP54231.1 - 3.2e-06 26.9 11.9 6.5e-06 25.9 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 OAP54232.1 - 3.6e-75 252.7 0.0 8e-75 251.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 OAP54232.1 - 1.4e-51 175.4 0.0 3.1e-51 174.2 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 OAP54232.1 - 6.2e-51 173.6 0.0 1.2e-50 172.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 OAP54232.1 - 7.5e-48 162.5 0.0 1.8e-47 161.3 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 OAP54232.1 - 4.7e-36 124.2 0.0 1.4e-35 122.7 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Condensation PF00668.15 OAP54232.1 - 9.2e-35 119.9 0.0 2e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 OAP54232.1 - 8.4e-31 106.2 0.0 2.3e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 OAP54232.1 - 2.4e-18 66.4 0.0 7e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP54232.1 - 1.1e-15 57.6 0.0 2.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP54232.1 - 2.9e-12 46.9 0.0 1.1e-11 45.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP54232.1 - 1.6e-11 43.9 0.0 4.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP54232.1 - 2e-09 37.9 0.0 2.1e-08 34.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP54232.1 - 9.5e-07 28.1 0.0 1.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 OAP54232.1 - 5.6e-06 26.5 0.2 3.3e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 OAP54232.1 - 8.7e-06 24.9 0.0 1.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 OAP54232.1 - 0.0004 19.8 0.0 0.00095 18.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 OAP54232.1 - 0.00072 18.6 0.0 0.003 16.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase HxxPF_rpt PF13745.1 OAP54232.1 - 0.0011 19.2 0.0 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain FSH1 PF03959.8 OAP54233.1 - 2.7e-32 111.9 0.0 3.1e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 OAP54233.1 - 2.4e-05 23.8 0.4 0.013 14.9 0.1 2.6 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 OAP54233.1 - 0.025 14.4 2.5 0.11 12.3 1.7 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family ADH_N PF08240.7 OAP54234.1 - 5.7e-06 26.0 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP54234.1 - 9.7e-05 21.9 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.17 OAP54235.1 - 3.7e-44 151.0 0.0 4.7e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 OAP54236.1 - 9.8e-27 93.9 0.1 1.4e-26 93.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 OAP54236.1 - 1.5e-07 30.6 2.6 2.9e-07 29.7 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP54236.1 - 2.6e-07 29.9 6.9 1.1e-05 24.5 1.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP54236.1 - 8.8e-07 28.9 0.5 1.7e-05 24.7 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP54236.1 - 6.7e-06 26.0 0.8 1.8e-05 24.6 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 OAP54236.1 - 1e-05 24.4 0.6 0.0078 14.8 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 OAP54236.1 - 6.1e-05 23.3 0.6 0.0006 20.1 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP54236.1 - 9.6e-05 22.5 0.4 0.00052 20.1 0.3 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP54236.1 - 0.00085 18.2 0.2 0.0015 17.4 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 OAP54236.1 - 0.0016 17.0 0.9 0.0027 16.2 0.7 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 OAP54236.1 - 0.002 17.2 2.1 0.004 16.2 1.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 OAP54236.1 - 0.0033 16.2 0.0 0.0072 15.1 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 OAP54236.1 - 0.011 14.6 0.8 2.2 7.0 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 OAP54236.1 - 0.027 13.5 0.1 0.076 12.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Rossmann-like PF10727.4 OAP54236.1 - 0.041 13.6 0.3 0.14 11.8 0.2 1.9 1 0 0 1 1 1 0 Rossmann-like domain IlvN PF07991.7 OAP54236.1 - 0.048 13.0 0.2 0.098 12.0 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_9 PF13454.1 OAP54236.1 - 0.07 12.9 0.6 3.6 7.3 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 OAP54236.1 - 0.071 12.4 0.7 0.12 11.7 0.5 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.19 OAP54236.1 - 0.09 11.8 2.0 0.098 11.7 0.2 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 OAP54236.1 - 0.1 12.1 2.7 0.098 12.2 0.5 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 OAP54236.1 - 0.11 12.4 0.2 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 OAP54236.1 - 0.13 11.9 0.3 0.23 11.1 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 OAP54237.1 - 1.2e-36 126.2 47.8 1.2e-36 126.2 33.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Aldolase_II PF00596.16 OAP54238.1 - 2.2e-27 95.8 0.2 2.8e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.13 OAP54239.1 - 1.9e-30 105.6 0.0 3.6e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_85 PF03644.8 OAP54239.1 - 0.044 12.9 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 DUF1495 PF07381.6 OAP54239.1 - 0.077 12.6 0.1 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) DUF2076 PF09849.4 OAP54239.1 - 6 6.8 13.9 1.9 8.4 4.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Aldolase_II PF00596.16 OAP54240.1 - 1.4e-26 93.1 0.6 1.8e-26 92.8 0.4 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Adaptin_N PF01602.15 OAP54241.1 - 1.5e-93 313.9 9.5 2.3e-93 313.2 6.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 OAP54241.1 - 3.3e-62 208.3 0.4 8.5e-62 206.9 0.3 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 OAP54241.1 - 8.5e-62 206.6 0.1 2.5e-61 205.1 0.1 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 OAP54241.1 - 2.9e-13 49.8 9.3 7.9e-08 32.4 0.0 5.2 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 OAP54241.1 - 2.2e-06 27.6 7.9 0.0071 16.2 0.0 4.0 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 OAP54241.1 - 0.00014 22.2 1.5 0.048 14.1 0.1 4.6 2 1 2 4 4 4 2 HEAT-like repeat HEAT PF02985.17 OAP54241.1 - 0.00033 20.4 1.9 0.2 11.8 0.1 4.7 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 OAP54241.1 - 0.02 14.6 0.8 0.76 9.6 0.0 4.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 OAP54241.1 - 0.14 12.7 0.5 86 4.0 0.0 4.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat AAA_33 PF13671.1 OAP54243.1 - 1.4e-14 54.1 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 OAP54243.1 - 1.2e-13 51.2 0.1 1.6e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 OAP54243.1 - 7.5e-12 46.1 0.1 1.5e-11 45.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP54243.1 - 9.6e-11 42.1 0.1 6.1e-10 39.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 OAP54243.1 - 3.1e-05 23.8 0.0 0.00034 20.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP54243.1 - 5.6e-05 23.3 0.0 7.7e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 OAP54243.1 - 5.6e-05 23.1 0.2 0.00017 21.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 OAP54243.1 - 5.8e-05 21.9 0.0 8.8e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 OAP54243.1 - 8.7e-05 22.2 0.0 0.00035 20.2 0.0 1.9 1 1 1 2 2 2 1 NACHT domain AAA_19 PF13245.1 OAP54243.1 - 0.00012 21.8 0.0 0.00028 20.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 OAP54243.1 - 0.00016 21.9 0.1 0.00022 21.4 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 OAP54243.1 - 0.00052 19.7 0.0 0.00069 19.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Viral_helicase1 PF01443.13 OAP54243.1 - 0.00059 19.4 0.3 0.039 13.4 0.0 2.2 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 OAP54243.1 - 0.00062 19.9 0.0 0.0014 18.7 0.0 1.6 2 0 0 2 2 1 1 RNA helicase Cytidylate_kin2 PF13189.1 OAP54243.1 - 0.00071 19.5 0.1 0.0026 17.7 0.0 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_25 PF13481.1 OAP54243.1 - 0.001 18.5 0.1 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP54243.1 - 0.0017 18.4 0.1 0.0023 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAP54243.1 - 0.0022 17.7 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) KTI12 PF08433.5 OAP54243.1 - 0.0027 16.9 0.4 0.0051 16.0 0.3 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 IPPT PF01715.12 OAP54243.1 - 0.0047 15.9 0.1 0.0074 15.3 0.1 1.4 1 1 0 1 1 1 1 IPP transferase DUF2075 PF09848.4 OAP54243.1 - 0.0053 15.7 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 OAP54243.1 - 0.0058 15.8 2.1 0.048 12.8 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 OAP54243.1 - 0.0061 15.6 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 OAP54243.1 - 0.0063 16.8 0.0 0.012 15.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 OAP54243.1 - 0.008 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.1 OAP54243.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 OAP54243.1 - 0.015 14.5 0.1 0.034 13.3 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein NTPase_1 PF03266.10 OAP54243.1 - 0.015 15.0 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 NTPase CoaE PF01121.15 OAP54243.1 - 0.015 14.6 0.0 0.043 13.2 0.0 1.8 1 0 0 1 1 1 0 Dephospho-CoA kinase Arch_ATPase PF01637.13 OAP54243.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase ADK PF00406.17 OAP54243.1 - 0.027 14.3 0.8 0.44 10.4 0.6 2.2 1 1 0 1 1 1 0 Adenylate kinase tRNA_lig_kinase PF08303.6 OAP54243.1 - 0.055 13.3 0.1 0.17 11.7 0.0 2.0 2 1 0 2 2 1 0 tRNA ligase kinase domain DNA_pol3_delta2 PF13177.1 OAP54243.1 - 0.062 12.9 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 DNA polymerase III, delta subunit PRK PF00485.13 OAP54243.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family VirE PF05272.6 OAP54243.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E NB-ARC PF00931.17 OAP54243.1 - 0.081 11.7 0.6 0.25 10.1 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain IPT PF01745.11 OAP54243.1 - 0.1 11.7 0.1 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Isopentenyl transferase KaiC PF06745.8 OAP54243.1 - 0.12 11.5 0.5 0.52 9.3 0.0 2.1 2 1 0 2 2 2 0 KaiC AAA_11 PF13086.1 OAP54243.1 - 0.12 11.8 0.4 0.5 9.8 0.3 1.9 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 OAP54243.1 - 0.13 11.7 0.2 0.68 9.3 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 OAP54243.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF836 PF05768.9 OAP54243.1 - 0.19 12.0 0.9 7.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) AAA_23 PF13476.1 OAP54243.1 - 0.54 10.5 1.9 0.91 9.8 1.3 1.7 1 1 0 1 1 1 0 AAA domain Vps26 PF03643.10 OAP54244.1 - 1.5e-129 430.6 0.5 1.7e-129 430.4 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 OAP54244.1 - 0.00014 21.7 0.2 2 8.2 0.0 3.4 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 OAP54244.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Sec7_N PF12783.2 OAP54245.1 - 1.2e-17 63.8 0.4 5.1e-17 61.8 0.3 2.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Dak2 PF02734.12 OAP54245.1 - 0.00039 20.1 2.4 0.00043 20.0 0.2 2.1 2 0 0 2 2 2 1 DAK2 domain DUF1981 PF09324.5 OAP54245.1 - 0.11 12.0 0.0 9.2 5.8 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1981) HEAT PF02985.17 OAP54245.1 - 0.4 10.9 4.3 2.4 8.4 0.1 4.2 3 0 0 3 3 3 0 HEAT repeat DUF872 PF05915.7 OAP54246.1 - 1.2 9.0 4.2 5 7.0 0.1 3.2 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF872) CFEM PF05730.6 OAP54247.1 - 0.0027 17.4 3.0 0.0027 17.4 2.1 2.7 2 1 0 2 2 2 1 CFEM domain UQ_con PF00179.21 OAP54248.1 - 8.9e-17 60.8 0.0 9.5e-17 60.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAP54248.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain Complex1_LYR_1 PF13232.1 OAP54249.1 - 8e-07 29.1 1.9 8.6e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAP54249.1 - 0.0051 16.5 3.7 0.0059 16.3 0.0 2.8 2 1 1 3 3 3 1 Complex 1 protein (LYR family) Cid2 PF09774.4 OAP54250.1 - 1.7e-39 135.3 0.0 2.2e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Fe_hyd_lg_C PF02906.9 OAP54251.1 - 6.3e-66 222.5 0.0 1.1e-65 221.7 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Sugar_tr PF00083.19 OAP54252.1 - 2.4e-110 369.2 17.8 3.1e-110 368.8 12.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP54252.1 - 3.3e-28 98.4 20.6 3.3e-28 98.4 14.2 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 OAP54252.1 - 0.0001 20.9 5.7 0.00027 19.6 0.8 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_1_like PF12832.2 OAP54252.1 - 0.00053 19.7 0.4 0.0039 16.9 0.0 2.6 3 0 0 3 3 3 1 MFS_1 like family PspC PF04024.7 OAP54252.1 - 0.0085 15.5 3.8 0.011 15.2 0.1 3.0 2 0 0 2 2 2 1 PspC domain Fapy_DNA_glyco PF01149.19 OAP54253.1 - 6.1e-24 84.6 0.1 1.3e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 OAP54253.1 - 3.8e-22 77.8 0.0 7.1e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Mitofilin PF09731.4 OAP54253.1 - 3.6 6.1 26.2 5.3 5.5 18.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC45 PF02724.9 OAP54253.1 - 5.5 4.9 15.5 7.4 4.4 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 OAP54254.1 - 4.3e-09 35.5 39.6 4.3e-09 35.5 27.4 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily FSH1 PF03959.8 OAP54255.1 - 1.2e-67 227.4 0.0 1.5e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 OAP54255.1 - 3.2e-07 30.4 0.9 3.5e-05 23.7 0.6 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP54255.1 - 2.4e-06 27.3 0.0 3.7e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP54255.1 - 0.042 13.2 0.9 9.8 5.5 0.1 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DLH PF01738.13 OAP54255.1 - 0.12 11.6 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family HSP70 PF00012.15 OAP54257.1 - 5.9e-81 272.1 3.4 7.5e-81 271.8 0.8 1.8 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 OAP54257.1 - 1.4e-07 30.4 0.1 2.2e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 OAP54257.1 - 0.00012 21.1 0.3 0.0016 17.4 0.2 2.1 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; Nucleoplasmin PF03066.10 OAP54257.1 - 0.026 14.0 5.4 0.066 12.7 3.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin BRAP2 PF07576.7 OAP54257.1 - 0.027 14.0 0.0 0.076 12.5 0.0 1.7 1 0 0 1 1 1 0 BRCA1-associated protein 2 Sigma70_ner PF04546.8 OAP54257.1 - 0.17 11.4 6.5 0.26 10.8 2.4 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 OAP54257.1 - 7.4 6.9 13.0 0.3 11.4 4.9 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 OAP54258.1 - 3.6e-33 114.7 31.0 2.6e-22 79.0 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP54258.1 - 2.1e-11 42.9 4.5 1.2e-06 27.1 0.0 2.8 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 OAP54258.1 - 1e-05 24.3 3.9 1e-05 24.3 2.7 3.1 1 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 OAP54258.1 - 0.0045 16.7 5.2 0.11 12.2 0.1 3.0 3 0 0 3 3 3 2 MFS_1 like family DUF998 PF06197.8 OAP54258.1 - 0.84 8.9 20.8 0.27 10.5 10.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF998) UNC-93 PF05978.11 OAP54258.1 - 2 7.8 8.1 0.077 12.4 0.3 2.4 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 ADH_zinc_N PF00107.21 OAP54260.1 - 1.3e-19 70.0 0.2 2e-19 69.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP54260.1 - 1.3e-13 51.8 0.0 3.6e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP54260.1 - 3.7e-07 29.8 0.0 7.4e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 OAP54260.1 - 0.0081 15.7 0.3 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PSI PF01437.20 OAP54262.1 - 6.5e-05 22.9 9.2 0.0001 22.3 6.4 1.6 1 1 0 1 1 1 1 Plexin repeat Yip1 PF04893.12 OAP54262.1 - 0.036 13.5 0.5 0.046 13.2 0.3 1.1 1 0 0 1 1 1 0 Yip1 domain FBA_2 PF07735.12 OAP54262.1 - 0.087 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 F-box associated PepSY_TM_2 PF13703.1 OAP54262.1 - 4.3 7.5 6.5 0.74 10.0 2.0 1.5 2 0 0 2 2 2 0 PepSY-associated TM helix Metallophos PF00149.23 OAP54263.1 - 1.2e-07 31.3 3.2 2.9e-07 30.0 2.2 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 OAP54264.1 - 2.5e-22 78.9 1.3 3.8e-22 78.4 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54264.1 - 2.1e-08 33.9 9.1 4.1e-08 32.9 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_A6 PF01829.11 OAP54264.1 - 0.1 11.6 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase A6 family DUF4407 PF14362.1 OAP54264.1 - 0.13 11.1 0.3 0.21 10.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_trans PF04082.13 OAP54265.1 - 3.2e-16 58.9 0.0 5.8e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54265.1 - 6.7e-09 35.5 12.0 1.2e-08 34.7 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 OAP54266.1 - 0.27 11.6 2.1 0.97 9.9 1.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP54266.1 - 0.29 11.5 2.6 1 9.8 1.8 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2 PF00096.21 OAP54267.1 - 3.2 8.2 6.8 1.4 9.4 2.8 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Thiolase_C PF02803.13 OAP54268.1 - 9.9e-12 44.3 0.5 1.4e-10 40.6 0.0 2.8 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 OAP54268.1 - 2e-05 24.1 0.0 0.0021 17.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 OAP54268.1 - 0.0012 17.9 0.1 0.025 13.5 0.0 2.8 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 OAP54268.1 - 0.015 14.8 0.1 0.32 10.4 0.0 2.3 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DUF3208 PF11482.3 OAP54268.1 - 0.02 15.0 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) SpoVAD PF07451.6 OAP54268.1 - 0.032 12.6 0.1 0.1 11.0 0.0 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 OAP54268.1 - 0.054 13.3 0.7 0.82 9.5 0.0 2.8 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain Fungal_trans PF04082.13 OAP54272.1 - 1.6e-13 50.1 0.1 2.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IDO PF01231.13 OAP54273.1 - 4.1e-152 506.5 0.0 4.7e-152 506.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase AA_permease_2 PF13520.1 OAP54274.1 - 4.6e-43 147.3 61.5 5.9e-43 146.9 42.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP54274.1 - 5.8e-19 67.7 51.5 8.3e-19 67.2 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3445 PF11927.3 OAP54275.1 - 2.7e-54 184.2 0.0 4.4e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.3 OAP54275.1 - 5.8e-43 146.9 5.0 7.3e-43 146.6 3.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GalP_UDP_tr_C PF02744.12 OAP54275.1 - 0.091 12.3 0.0 10 5.6 0.0 2.6 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain ADH_N PF08240.7 OAP54276.1 - 5.7e-22 77.5 1.5 5.7e-22 77.5 1.0 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP54276.1 - 8.4e-13 47.9 0.0 1.4e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP54276.1 - 9e-05 22.1 0.1 0.00015 21.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 OAP54276.1 - 0.00025 20.2 0.3 0.00041 19.5 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAP54276.1 - 0.0045 17.0 0.1 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_11 PF08241.7 OAP54276.1 - 0.023 15.1 0.0 0.06 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_nitro PF00148.14 OAP54276.1 - 0.042 12.4 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.16 OAP54276.1 - 0.091 12.3 0.3 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.11 OAP54276.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 OAP54276.1 - 0.11 12.1 0.1 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhyH PF05721.8 OAP54277.1 - 6.2e-18 65.6 0.0 8e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2360 PF10152.4 OAP54277.1 - 0.12 12.7 3.2 0.22 11.7 2.2 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CorA PF01544.13 OAP54278.1 - 1.4e-09 37.3 6.2 3.6e-09 36.0 4.3 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_5 PF12695.2 OAP54279.1 - 1.4e-15 57.2 0.0 2.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP54279.1 - 1.9e-15 57.3 0.1 4.5e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family CorA PF01544.13 OAP54279.1 - 2.1e-06 27.0 1.7 2.1e-06 27.0 1.2 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein AXE1 PF05448.7 OAP54279.1 - 3.9e-05 22.2 0.1 0.049 12.1 0.1 2.5 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 OAP54279.1 - 0.00085 18.5 0.1 0.03 13.5 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAP54279.1 - 0.0022 17.6 0.0 0.005 16.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 OAP54279.1 - 0.0045 16.7 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 OAP54279.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Pox_G7 PF05503.7 OAP54279.1 - 0.11 11.0 0.1 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G7-like BatD PF13584.1 OAP54279.1 - 0.22 10.0 0.1 0.36 9.3 0.1 1.3 1 0 0 1 1 1 0 Oxygen tolerance LRR_5 PF13306.1 OAP54280.1 - 1.5e-05 24.6 2.8 0.003 17.2 0.0 2.5 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) Ecm33 PF12454.3 OAP54280.1 - 0.00015 21.5 0.2 0.00071 19.4 0.2 2.3 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 OAP54280.1 - 0.00028 20.8 6.4 0.93 9.4 0.0 3.9 1 1 3 4 4 4 3 Receptor L domain HhH-GPD PF00730.20 OAP54281.1 - 2.5e-15 56.6 0.0 4.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UCR_14kD PF02271.11 OAP54282.1 - 3.5e-46 155.2 0.1 4e-46 155.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 OAP54283.1 - 4.1e-67 221.9 4.8 3e-23 81.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PmbA_TldD PF01523.11 OAP54283.1 - 0.00044 19.6 0.0 0.00062 19.1 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Tcf25 PF04910.9 OAP54284.1 - 2.5e-84 283.3 1.2 3.2e-83 279.6 0.1 2.1 2 0 0 2 2 2 2 Transcriptional repressor TCF25 DUF605 PF04652.11 OAP54284.1 - 9 5.5 29.7 0.34 10.2 6.3 2.3 2 0 0 2 2 2 0 Vta1 like PP2C PF00481.16 OAP54285.1 - 3.6e-41 141.2 0.0 6.3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 OAP54285.1 - 6.8e-05 22.3 0.0 0.00018 20.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 OAP54285.1 - 0.006 16.2 0.0 1.3 8.6 0.0 2.6 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) 60KD_IMP PF02096.15 OAP54286.1 - 5.4e-11 42.5 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 OAP54287.1 - 1.8e-19 69.8 0.0 2.9e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAP54287.1 - 0.00029 21.0 0.0 0.00054 20.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAP54287.1 - 0.011 15.8 0.1 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain AAA_5 PF07728.9 OAP54287.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UQ_con PF00179.21 OAP54288.1 - 1.1e-47 160.9 0.0 1.2e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP54288.1 - 3.9e-05 23.4 0.0 0.0003 20.5 0.0 2.0 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 OAP54288.1 - 0.084 12.7 0.4 0.17 11.7 0.1 1.6 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.16 OAP54289.1 - 7.9e-68 228.6 0.0 1.1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 OAP54289.1 - 2.2e-36 124.3 0.0 3.6e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 OAP54289.1 - 4.7e-29 101.0 0.0 8.5e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 OAP54289.1 - 3e-08 33.1 0.0 5.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 OAP54289.1 - 2.5e-05 23.1 0.1 0.083 11.5 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II NAD_synthase PF02540.12 OAP54289.1 - 0.0068 15.3 0.1 0.018 13.9 0.1 1.8 1 1 0 1 1 1 1 NAD synthase Porin_3 PF01459.17 OAP54290.1 - 1.6e-63 214.5 5.9 2.2e-63 214.1 4.1 1.2 1 0 0 1 1 1 1 Eukaryotic porin MHC_I_C PF06623.6 OAP54290.1 - 0.056 12.9 0.5 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 MHC_I C-terminus DnaJ PF00226.26 OAP54291.1 - 1.5e-19 69.4 0.4 1.5e-19 69.4 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain Adeno_E3 PF06040.6 OAP54291.1 - 0.12 12.3 0.0 9.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein Branch PF02485.16 OAP54291.1 - 0.15 11.1 0.0 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 Core-2/I-Branching enzyme Peptidase_M24 PF00557.19 OAP54292.1 - 3.8e-44 150.7 0.1 5e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Chorismate_synt PF01264.16 OAP54293.1 - 1.9e-132 440.9 0.0 2.3e-132 440.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Kelch_4 PF13418.1 OAP54294.1 - 0.00015 21.4 9.8 0.23 11.2 0.1 4.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Ribonuc_red_lgC PF02867.10 OAP54295.1 - 3.4e-219 728.9 0.0 5.9e-219 728.1 0.0 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 OAP54295.1 - 2.5e-24 84.8 0.0 6.1e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 OAP54295.1 - 2.5e-18 66.2 0.1 6.9e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain SAP PF02037.22 OAP54297.1 - 1.4e-09 37.2 0.0 3e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain Asp PF00026.18 OAP54298.1 - 5.2e-71 239.4 10.0 7.3e-71 238.9 6.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAP54298.1 - 7.7e-08 32.4 0.4 7.7e-08 32.4 0.3 2.2 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAP54298.1 - 7.1e-06 26.4 0.2 0.033 14.6 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 OAP54298.1 - 0.059 13.1 0.0 11 5.8 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease adh_short PF00106.20 OAP54299.1 - 1.8e-26 93.0 1.2 3.6e-26 92.0 0.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54299.1 - 1.8e-17 63.9 0.3 2.3e-17 63.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54299.1 - 1.1e-07 31.6 0.8 9.3e-07 28.6 0.6 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 OAP54299.1 - 2e-05 23.4 0.5 3e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP54299.1 - 0.00019 20.9 0.2 0.00048 19.6 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP54299.1 - 0.00026 21.0 0.1 0.00057 19.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding DFP PF04127.10 OAP54299.1 - 0.011 15.3 0.3 0.017 14.7 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein FMN_red PF03358.10 OAP54299.1 - 0.067 12.7 0.4 0.13 11.7 0.1 1.5 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Fiji_64_capsid PF05880.6 OAP54299.1 - 0.079 11.2 0.1 0.11 10.8 0.1 1.1 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein Aa_trans PF01490.13 OAP54300.1 - 8.9e-77 258.2 28.2 1.1e-76 258.0 19.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Zip PF02535.17 OAP54302.1 - 0.69 8.8 5.8 0.88 8.5 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 OAP54302.1 - 1.4 8.2 9.1 2.4 7.4 6.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CTP_transf_2 PF01467.21 OAP54304.1 - 0.064 13.3 0.0 0.97 9.4 0.0 2.4 2 2 0 2 2 2 0 Cytidylyltransferase AA_permease_2 PF13520.1 OAP54305.1 - 5.2e-38 130.6 15.1 5.2e-38 130.6 10.5 1.6 2 0 0 2 2 2 1 Amino acid permease DUF2809 PF10990.3 OAP54305.1 - 6.9 7.1 10.0 0.75 10.2 0.4 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2809) Ank_2 PF12796.2 OAP54306.1 - 1.6e-128 419.3 41.1 3e-14 53.1 1.3 11.3 2 2 15 17 17 17 17 Ankyrin repeats (3 copies) Ank PF00023.25 OAP54306.1 - 7e-51 167.5 55.4 2.4e-05 23.8 0.0 21.7 21 1 0 21 21 21 16 Ankyrin repeat Ank_3 PF13606.1 OAP54306.1 - 2.9e-43 141.5 43.9 0.0056 16.7 0.1 22.8 23 1 1 24 24 24 10 Ankyrin repeat Ank_4 PF13637.1 OAP54306.1 - 3.8e-40 135.5 31.9 0.00023 21.5 0.1 15.4 12 3 4 16 16 16 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP54306.1 - 8.1e-28 95.8 38.6 0.016 15.4 0.0 18.7 11 5 10 21 21 21 9 Ankyrin repeats (many copies) Clr5 PF14420.1 OAP54306.1 - 5e-13 48.7 0.7 1e-12 47.7 0.5 1.5 1 0 0 1 1 1 1 Clr5 domain Shigella_OspC PF06128.6 OAP54306.1 - 0.024 14.1 0.1 88 2.4 0.0 4.9 5 1 1 6 6 6 0 Shigella flexneri OspC protein ACT_4 PF13291.1 OAP54308.1 - 0.36 11.1 2.5 21 5.5 0.4 2.4 2 0 0 2 2 2 0 ACT domain CorA PF01544.13 OAP54308.1 - 0.98 8.3 5.5 4.2 6.3 3.8 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 OAP54309.1 - 2.8e-18 65.9 0.0 7.6e-18 64.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54309.1 - 0.00012 21.2 0.0 0.001 18.1 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Ribosomal_60s PF00428.14 OAP54310.1 - 3.4e-26 91.4 13.2 4.2e-26 91.1 9.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Fe-ADH PF00465.14 OAP54311.1 - 3e-69 233.4 0.0 3.7e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAP54311.1 - 2e-11 43.6 0.0 1.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Acyl_transf_3 PF01757.17 OAP54312.1 - 1.4e-26 93.1 33.1 2e-26 92.6 23.0 1.2 1 0 0 1 1 1 1 Acyltransferase family RTA1 PF04479.8 OAP54313.1 - 4.4e-42 144.1 2.8 6.1e-42 143.6 1.9 1.1 1 0 0 1 1 1 1 RTA1 like protein zf-H2C2_2 PF13465.1 OAP54315.1 - 6e-13 48.3 11.4 4.9e-08 32.8 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 OAP54315.1 - 8.8e-12 44.6 13.9 5e-06 26.5 1.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP54315.1 - 1.1e-10 41.0 14.4 2.3e-05 24.3 1.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAP54315.1 - 4.9e-07 29.7 2.1 0.07 13.3 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP54315.1 - 0.00031 20.8 5.5 0.015 15.4 0.2 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-BED PF02892.10 OAP54315.1 - 0.5 10.1 4.6 1.2 8.9 0.7 2.4 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.17 OAP54315.1 - 0.87 9.7 3.0 4.7 7.3 2.2 2.1 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 OAP54315.1 - 4.6 7.2 11.1 15 5.6 0.3 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Pkinase PF00069.20 OAP54316.1 - 4.1e-36 124.4 0.0 5.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54316.1 - 2.5e-14 52.9 0.0 3.2e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP54316.1 - 0.0077 15.9 0.0 0.48 10.1 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family CYSTM PF12734.2 OAP54316.1 - 2 8.5 4.8 1.3 9.1 0.8 2.4 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance adh_short_C2 PF13561.1 OAP54318.1 - 6.8e-26 91.5 0.1 8.5e-26 91.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP54318.1 - 3.5e-23 82.3 0.0 6.1e-23 81.5 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP54318.1 - 2.8e-10 40.1 0.0 9.7e-10 38.3 0.0 1.7 2 0 0 2 2 2 1 KR domain ST7 PF04184.7 OAP54318.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 ST7 protein Formyl_trans_N PF00551.14 OAP54319.1 - 8.6e-22 77.5 0.0 1.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Zn_clus PF00172.13 OAP54320.1 - 7.8e-07 28.8 10.5 7.8e-07 28.8 7.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP54320.1 - 0.011 14.3 2.2 0.019 13.5 1.6 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain Beta-lactamase PF00144.19 OAP54321.1 - 7e-29 100.8 0.7 3.7e-28 98.5 0.5 1.9 1 1 0 1 1 1 1 Beta-lactamase Pex19 PF04614.7 OAP54322.1 - 4.7e-55 186.9 17.5 5.3e-54 183.4 10.1 2.8 2 1 0 2 2 2 1 Pex19 protein family Histone_HNS PF00816.16 OAP54322.1 - 0.04 14.4 0.9 0.2 12.1 0.0 2.7 3 1 0 3 3 3 0 H-NS histone family Neuromodulin_N PF10580.4 OAP54322.1 - 0.087 12.4 0.1 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Gap junction protein N-terminal region DUF2514 PF10721.4 OAP54322.1 - 0.53 9.9 12.8 0.91 9.2 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Peptidase_S64 PF08192.6 OAP54322.1 - 2.7 6.1 9.2 3.7 5.7 6.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 NST1 PF13945.1 OAP54322.1 - 4.2 7.3 10.5 8.9 6.3 7.3 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator DNA_pol_viral_N PF00242.12 OAP54322.1 - 6 5.7 9.1 8.8 5.2 6.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Hid1 PF12722.2 OAP54322.1 - 9.1 3.8 10.0 13 3.3 6.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF533 PF04391.7 OAP54324.1 - 0.0085 15.4 0.2 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF533) DUF3318 PF11780.3 OAP54324.1 - 0.074 12.6 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) MHC2-interact PF09307.5 OAP54324.1 - 0.088 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 CLIP, MHC2 interacting DUF1980 PF09323.5 OAP54324.1 - 1.4 8.6 4.3 0.55 9.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) PQ-loop PF04193.9 OAP54325.1 - 4.5e-37 125.4 10.6 1.3e-18 66.3 1.7 2.8 3 0 0 3 3 3 2 PQ loop repeat Transformer PF06495.6 OAP54325.1 - 0.028 14.3 5.8 0.042 13.7 4.0 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein BCD PF15461.1 OAP54325.1 - 1.2 8.4 7.5 6.1 6.1 3.9 2.6 2 1 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase Fungal_trans PF04082.13 OAP54326.1 - 8.8e-15 54.2 0.9 1.4e-14 53.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 OAP54327.1 - 3.6e-25 88.3 0.2 5.5e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54327.1 - 6.5e-09 35.5 10.1 1.2e-08 34.6 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BPL_LplA_LipB PF03099.14 OAP54328.1 - 6.2e-16 58.5 0.0 1.9e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family MR_MLE_C PF13378.1 OAP54329.1 - 2.3e-29 101.5 0.0 4.3e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 OAP54329.1 - 8.5e-20 70.8 0.0 2.4e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 OAP54329.1 - 2.2e-07 31.2 0.0 1.5e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain adh_short PF00106.20 OAP54330.1 - 6.5e-29 100.9 2.5 7e-29 100.8 1.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54330.1 - 1.9e-23 83.5 0.1 2.2e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54330.1 - 8e-10 38.6 1.3 1.4e-09 37.8 0.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP54330.1 - 0.016 14.6 0.2 0.038 13.4 0.1 1.7 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 OAP54331.1 - 3.1e-73 246.8 24.0 3.9e-73 246.5 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP54331.1 - 4.1e-19 68.5 25.2 4.1e-19 68.5 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.1 OAP54332.1 - 7.6e-31 107.7 0.0 1e-30 107.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP54332.1 - 6.5e-28 97.7 0.8 8.4e-28 97.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP54332.1 - 3.2e-11 43.2 0.1 4.6e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP54332.1 - 0.0043 16.5 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP54332.1 - 0.019 14.7 0.8 0.052 13.3 0.6 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 OAP54333.1 - 2.4e-28 98.7 0.0 4.4e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 OAP54334.1 - 5.4e-22 78.8 0.0 3.4e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP54334.1 - 6.3e-20 70.8 0.5 6.6e-17 60.8 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP54334.1 - 1.3e-07 30.9 0.0 3.4e-05 22.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP54334.1 - 3.7e-07 30.2 0.0 0.00025 20.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP54334.1 - 1.1e-05 25.3 2.1 1.3e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP54334.1 - 0.00021 21.1 0.1 0.025 14.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Malic_M PF03949.10 OAP54334.1 - 0.15 11.6 0.0 18 4.8 0.0 2.4 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain HI0933_like PF03486.9 OAP54334.1 - 0.19 10.1 0.1 3.7 5.9 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 OAP54334.1 - 0.2 10.5 0.4 2.7 6.8 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 OAP54334.1 - 0.26 10.3 0.3 6.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 OAP54334.1 - 0.31 11.4 0.8 30 5.1 0.0 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 OAP54335.1 - 9.8e-26 90.6 0.9 3.8e-25 88.7 0.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54335.1 - 3.4e-19 69.5 0.0 6.8e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54335.1 - 2.3e-07 30.6 2.2 1.3e-05 24.9 1.5 2.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP54335.1 - 6e-07 29.1 0.0 1e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP54335.1 - 1.3e-05 24.1 0.1 1.7e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAP54336.1 - 1.2e-16 61.0 0.2 1.8e-16 60.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP54336.1 - 2.8e-06 27.1 0.1 4.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP54336.1 - 3.7e-05 23.5 0.0 5.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 OAP54336.1 - 0.00059 19.9 0.1 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 OAP54336.1 - 0.0021 17.1 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 OAP54336.1 - 0.0022 17.2 0.6 0.0047 16.1 0.2 1.6 2 0 0 2 2 2 1 NmrA-like family Sugar_tr PF00083.19 OAP54337.1 - 6.6e-76 255.6 22.1 7.9e-76 255.4 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP54337.1 - 1.1e-21 77.0 40.4 5.3e-21 74.7 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Prim_Zn_Ribbon PF08273.7 OAP54337.1 - 0.14 12.2 0.8 0.27 11.3 0.6 1.4 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Fungal_trans_2 PF11951.3 OAP54338.1 - 0.0054 15.3 0.1 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 OAP54339.1 - 1.1e-48 165.7 0.0 2.2e-33 115.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54339.1 - 8.1e-21 74.2 0.0 7.7e-20 71.0 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP54339.1 - 6.7e-09 35.1 0.0 8.3e-08 31.5 0.0 2.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 OAP54339.1 - 0.00034 20.4 0.2 0.0017 18.1 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Alg14 PF08660.6 OAP54341.1 - 8.1e-47 159.3 0.0 1.6e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ima1_N PF09779.4 OAP54342.1 - 9.7e-35 119.9 4.7 1.7e-34 119.1 3.2 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.6 OAP54342.1 - 2.3 7.9 6.6 0.13 11.8 0.6 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FYVE PF01363.16 OAP54342.1 - 3.1 7.7 6.8 26 4.8 4.7 2.2 1 1 0 1 1 1 0 FYVE zinc finger EMP24_GP25L PF01105.19 OAP54343.1 - 3.7e-49 166.9 0.0 4.2e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cep57_CLD_2 PF14197.1 OAP54345.1 - 0.071 13.0 3.9 0.24 11.3 1.2 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 LCD1 PF09798.4 OAP54345.1 - 0.23 9.3 6.2 0.39 8.6 4.3 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Tup_N PF08581.5 OAP54345.1 - 0.24 11.6 7.2 21 5.4 0.0 2.7 2 0 0 2 2 2 0 Tup N-terminal LPP20 PF02169.11 OAP54346.1 - 0.0074 16.3 2.6 0.011 15.7 1.8 1.2 1 0 0 1 1 1 1 LPP20 lipoprotein AAA_13 PF13166.1 OAP54346.1 - 0.018 13.5 1.4 0.02 13.3 1.0 1.0 1 0 0 1 1 1 0 AAA domain DUF2756 PF10956.3 OAP54346.1 - 0.025 14.8 2.1 0.036 14.3 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Tektin PF03148.9 OAP54346.1 - 0.034 12.7 3.0 0.043 12.3 2.1 1.1 1 0 0 1 1 1 0 Tektin family WD40 PF00400.27 OAP54347.1 - 5.2e-47 156.1 17.0 2.2e-11 43.1 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 OAP54347.1 - 7e-08 31.0 3.5 0.022 12.9 0.1 4.7 3 1 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAP54347.1 - 5.2e-06 25.4 0.0 0.09 11.5 0.0 3.2 1 1 1 2 2 2 2 Nup133 N terminal like DUF3312 PF11768.3 OAP54347.1 - 0.041 12.1 0.0 0.062 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF202 PF02656.10 OAP54348.1 - 4.6e-12 45.9 4.3 4.6e-12 45.9 3.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 OAP54348.1 - 0.042 12.4 0.7 0.053 12.1 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CoA_binding_3 PF13727.1 OAP54348.1 - 0.22 11.3 2.3 0.26 11.0 1.6 1.2 1 0 0 1 1 1 0 CoA-binding domain Tctex-1 PF03645.8 OAP54349.1 - 2.2e-30 104.5 0.0 3.7e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Tctex-1 family DUF3425 PF11905.3 OAP54350.1 - 2.1e-18 66.5 0.3 4.2e-18 65.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP54350.1 - 0.00066 19.5 18.3 0.0032 17.4 12.7 1.9 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 OAP54350.1 - 0.0077 15.9 0.7 0.016 14.9 0.5 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper BMFP PF04380.8 OAP54350.1 - 0.13 12.4 6.9 0.21 11.7 4.8 1.4 1 0 0 1 1 1 0 Membrane fusogenic activity bZIP_Maf PF03131.12 OAP54350.1 - 0.15 12.3 9.7 0.29 11.4 6.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Seadorna_VP6 PF07407.6 OAP54350.1 - 0.28 9.8 0.4 0.4 9.3 0.3 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein HAUS-augmin3 PF14932.1 OAP54350.1 - 0.83 8.7 7.1 1.2 8.2 4.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 RapA_C PF12137.3 OAP54350.1 - 2 7.1 9.0 2.6 6.7 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal bZIP_2 PF07716.10 OAP54350.1 - 3.8 7.4 20.3 2.1e+02 1.8 14.1 2.2 1 1 0 1 1 1 0 Basic region leucine zipper G-alpha PF00503.15 OAP54351.1 - 1.5e-100 336.6 0.0 1.8e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAP54351.1 - 1.1e-12 47.5 0.8 1.1e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 OAP54351.1 - 0.00059 20.3 0.5 1.1 9.7 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 OAP54351.1 - 0.013 15.4 0.1 0.2 11.6 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAP54351.1 - 0.029 13.7 0.0 1.6 8.1 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Zn_clus PF00172.13 OAP54352.1 - 2.6e-08 33.6 7.7 2.6e-08 33.6 5.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 OAP54353.1 - 4e-45 154.2 0.4 5.9e-45 153.7 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 OAP54353.1 - 6.8e-13 48.0 0.6 2.2e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 OAP54353.1 - 1.3e-06 28.3 0.3 3e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAP54353.1 - 1.4e-06 27.6 0.5 2.3e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAP54353.1 - 9.6e-06 24.9 0.6 0.00026 20.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP54353.1 - 1.4e-05 25.0 0.3 2.9e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP54353.1 - 5.9e-05 22.2 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAP54353.1 - 0.0011 17.8 0.4 0.0019 17.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP54353.1 - 0.0015 18.6 0.0 0.074 13.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP54353.1 - 0.0026 16.8 1.5 0.019 14.0 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 OAP54353.1 - 0.0095 14.8 0.1 0.018 13.9 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAP54353.1 - 0.013 14.4 0.1 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 OAP54353.1 - 0.013 15.8 0.2 0.034 14.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 OAP54353.1 - 0.037 13.6 0.1 0.081 12.5 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 OAP54353.1 - 0.038 12.4 0.2 0.057 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 OAP54353.1 - 0.049 13.4 1.2 0.16 11.7 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding NUDIX PF00293.23 OAP54354.1 - 3.1e-17 62.4 0.1 5.3e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 OAP54354.1 - 6.8e-10 39.1 0.0 2.2e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 OAP54354.1 - 2e-06 27.2 1.4 3.5e-06 26.4 1.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Fungal_trans PF04082.13 OAP54355.1 - 2.8e-25 88.6 0.0 4.9e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54355.1 - 0.00038 20.2 8.2 0.00038 20.2 5.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mnd1 PF03962.10 OAP54355.1 - 0.25 10.9 0.1 0.43 10.2 0.0 1.3 1 0 0 1 1 1 0 Mnd1 family 2-Hacid_dh_C PF02826.14 OAP54356.1 - 2.1e-50 170.3 0.0 2.8e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP54356.1 - 8e-17 60.9 0.0 1.2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP54356.1 - 4e-06 26.7 0.0 1.6e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 OAP54356.1 - 0.07 12.6 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AAA_22 PF13401.1 OAP54357.1 - 1.5e-06 28.4 0.1 8.7e-05 22.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 OAP54357.1 - 1.8e-06 27.7 0.1 1.4e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP54357.1 - 0.00086 19.3 0.3 0.0088 16.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 OAP54357.1 - 0.0052 17.5 0.0 0.025 15.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAP54357.1 - 0.014 14.8 0.3 0.09 12.1 0.0 2.5 3 1 0 3 3 3 0 AAA-like domain AAA_18 PF13238.1 OAP54357.1 - 0.02 15.1 0.0 0.059 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain FA_FANCE PF11510.3 OAP54357.1 - 0.032 13.3 0.1 0.24 10.5 0.0 2.1 1 1 1 2 2 2 0 Fanconi Anaemia group E protein FANCE Ank_2 PF12796.2 OAP54357.1 - 0.04 14.2 0.0 0.48 10.7 0.0 2.8 2 1 0 2 2 1 0 Ankyrin repeats (3 copies) AAA_30 PF13604.1 OAP54357.1 - 0.051 13.1 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAP54357.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 OAP54357.1 - 0.061 12.7 0.0 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 OAP54357.1 - 0.077 11.9 0.0 7.9 5.3 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.1 OAP54357.1 - 0.081 12.4 0.5 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 OAP54357.1 - 0.09 13.0 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Ank_4 PF13637.1 OAP54357.1 - 0.09 13.3 0.1 17 6.0 0.0 3.7 4 0 0 4 4 3 0 Ankyrin repeats (many copies) MMR_HSR1 PF01926.18 OAP54357.1 - 0.099 12.6 0.0 6.3 6.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ank PF00023.25 OAP54357.1 - 0.11 12.3 0.1 5.1 7.0 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat KxDL PF10241.4 OAP54357.1 - 0.25 11.2 1.2 0.68 9.8 0.8 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein zf-C2H2 PF00096.21 OAP54358.1 - 6.5e-09 35.6 12.2 0.0014 18.8 0.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP54358.1 - 3.6e-07 30.0 13.0 0.017 15.3 0.2 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP54358.1 - 0.001 19.2 0.1 0.001 19.2 0.1 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.2 OAP54358.1 - 0.014 15.5 0.6 0.062 13.5 0.4 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Methyltransf_33 PF10017.4 OAP54359.1 - 4.8e-29 100.8 0.0 1.2e-28 99.5 0.0 1.6 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 OAP54359.1 - 0.0034 17.7 0.0 0.011 16.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.19 OAP54360.1 - 7.3e-87 291.8 25.9 8.8e-87 291.5 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP54360.1 - 1.3e-16 60.2 28.2 1.3e-16 60.2 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 OAP54361.1 - 8.2e-31 107.0 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54361.1 - 3e-11 42.8 0.1 5.3e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP54361.1 - 0.23 11.1 1.6 1.4 8.6 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family HET PF06985.6 OAP54362.1 - 3.9e-21 75.6 5.0 3.1e-18 66.2 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_2 PF07724.9 OAP54364.1 - 2.8e-47 160.7 0.1 1.6e-45 155.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 OAP54364.1 - 2.8e-26 91.2 0.2 1e-25 89.4 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 OAP54364.1 - 4.7e-21 75.3 0.1 1.9e-10 41.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAP54364.1 - 4.7e-13 49.0 4.6 1.5e-08 34.4 0.0 3.8 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAP54364.1 - 2.9e-11 43.6 0.6 0.0003 20.9 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 OAP54364.1 - 5.1e-10 39.6 10.4 0.00048 20.1 0.1 5.0 3 2 2 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.21 OAP54364.1 - 1.5e-07 31.0 3.4 4.5e-05 22.9 0.1 2.6 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 OAP54364.1 - 3e-07 30.4 0.5 0.029 14.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 OAP54364.1 - 2.1e-06 27.6 6.1 0.22 11.1 0.1 4.7 3 2 0 3 3 3 2 Archaeal ATPase AAA_18 PF13238.1 OAP54364.1 - 1.6e-05 25.1 2.4 0.096 12.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 OAP54364.1 - 1.7e-05 24.5 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 OAP54364.1 - 4.6e-05 23.1 0.0 0.021 14.4 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 OAP54364.1 - 6.6e-05 22.5 0.0 0.016 14.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 OAP54364.1 - 7.1e-05 22.8 1.4 0.066 13.1 0.0 3.8 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 OAP54364.1 - 7.1e-05 22.2 0.1 0.15 11.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 OAP54364.1 - 0.00012 22.9 7.8 0.043 14.6 0.0 3.9 4 2 0 4 4 2 2 AAA domain AAA_25 PF13481.1 OAP54364.1 - 0.00061 19.2 1.5 1.3 8.3 0.0 3.3 3 1 0 3 3 3 2 AAA domain ABC_tran PF00005.22 OAP54364.1 - 0.00064 20.0 0.8 0.39 11.0 0.0 3.3 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 OAP54364.1 - 0.0013 18.9 0.0 0.59 10.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 OAP54364.1 - 0.0013 17.9 0.3 2.9 6.9 0.0 3.7 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.4 OAP54364.1 - 0.0022 16.6 0.0 0.14 10.7 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 OAP54364.1 - 0.0054 16.6 0.6 3.3 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.17 OAP54364.1 - 0.0058 16.0 0.0 0.66 9.3 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ResIII PF04851.10 OAP54364.1 - 0.0075 16.1 5.0 3.5 7.4 0.0 3.7 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 OAP54364.1 - 0.011 15.2 0.0 0.86 9.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ERM PF00769.14 OAP54364.1 - 0.012 15.1 14.1 0.02 14.4 9.8 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF815 PF05673.8 OAP54364.1 - 0.013 14.3 0.2 0.6 8.9 0.1 3.1 3 2 0 3 3 2 0 Protein of unknown function (DUF815) DUF258 PF03193.11 OAP54364.1 - 0.018 14.1 0.0 4.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 OAP54364.1 - 0.023 15.2 1.5 0.92 10.0 0.0 3.1 3 0 0 3 3 2 0 Miro-like protein UPF0079 PF02367.12 OAP54364.1 - 0.028 14.0 0.0 7.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 OAP54364.1 - 0.046 13.2 0.0 0.84 9.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 OAP54364.1 - 0.05 13.1 0.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Torsin PF06309.6 OAP54364.1 - 0.069 13.0 0.0 0.85 9.5 0.0 2.5 3 0 0 3 3 2 0 Torsin AAA_24 PF13479.1 OAP54364.1 - 0.069 12.7 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 OAP54364.1 - 0.086 12.3 0.1 16 4.9 0.0 2.7 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 OAP54364.1 - 0.12 11.9 7.9 0.3 10.6 0.0 4.0 4 1 1 5 5 4 0 AAA domain UvrD-helicase PF00580.16 OAP54364.1 - 0.12 11.6 3.9 0.48 9.6 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain GAS PF13851.1 OAP54364.1 - 0.19 10.8 11.4 0.41 9.8 7.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 OAP54364.1 - 0.36 10.3 11.6 0.88 9.1 8.0 1.6 1 0 0 1 1 1 0 IncA protein AAA_10 PF12846.2 OAP54364.1 - 0.38 10.1 4.0 0.39 10.1 0.0 3.0 3 2 0 3 3 2 0 AAA-like domain AAA_15 PF13175.1 OAP54364.1 - 0.42 9.6 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain GrpE PF01025.14 OAP54364.1 - 0.51 9.8 11.6 1.6 8.2 8.0 1.9 1 1 0 1 1 1 0 GrpE DivIC PF04977.10 OAP54364.1 - 0.74 9.3 15.8 0.93 9.0 5.8 2.8 1 1 1 2 2 2 0 Septum formation initiator Bacillus_HBL PF05791.6 OAP54364.1 - 1.2 8.5 5.7 2.8 7.2 4.0 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Rootletin PF15035.1 OAP54364.1 - 2 8.3 15.1 0.93 9.4 8.4 1.9 2 0 0 2 2 1 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.14 OAP54364.1 - 2.3 5.9 6.1 3.1 5.5 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 OAP54364.1 - 2.9 6.7 10.2 5.1 5.9 7.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 OAP54364.1 - 4.7 6.1 9.9 8.4 5.3 6.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 BTB PF00651.26 OAP54365.1 - 5.7e-08 32.7 0.0 8.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Daxx PF03344.10 OAP54366.1 - 3.2 6.1 19.6 3.7 5.9 13.6 1.0 1 0 0 1 1 1 0 Daxx Family Macoilin PF09726.4 OAP54366.1 - 4.6 5.3 10.2 5.3 5.1 7.1 1.0 1 0 0 1 1 1 0 Transmembrane protein EF1_GNE PF00736.14 OAP54367.1 - 1.7e-30 104.5 6.0 3.4e-30 103.5 4.2 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 OAP54367.1 - 6.5e-13 48.5 5.1 6.5e-13 48.5 3.6 3.0 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 OAP54367.1 - 0.058 13.3 0.2 0.23 11.4 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP54367.1 - 0.09 13.2 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DHO_dh PF01180.16 OAP54368.1 - 9.4e-17 60.8 0.0 1.3e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase RNB PF00773.14 OAP54369.1 - 6.7e-81 272.0 0.0 1.7e-80 270.7 0.0 1.7 2 0 0 2 2 2 1 RNB domain GLE1 PF07817.8 OAP54370.1 - 3.7e-10 39.1 0.4 0.00068 18.6 0.0 3.7 3 1 0 3 3 3 2 GLE1-like protein MIP-T3 PF10243.4 OAP54370.1 - 0.61 8.4 49.6 0.84 8.0 34.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Abhydrolase_6 PF12697.2 OAP54371.1 - 8.3e-30 104.3 0.5 1.2e-29 103.8 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP54371.1 - 4.6e-15 55.8 0.0 7.6e-14 51.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP54371.1 - 4.8e-14 52.3 0.0 2.2e-13 50.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP54371.1 - 0.0078 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF3530 PF12048.3 OAP54371.1 - 0.04 12.8 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF543 PF04418.7 OAP54371.1 - 0.12 12.2 0.1 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) COesterase PF00135.23 OAP54372.1 - 4.7e-77 259.9 0.0 6.9e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP54372.1 - 9.3e-11 41.7 0.1 2.8e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP54372.1 - 0.0025 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 OAP54372.1 - 0.072 11.7 0.0 4.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 OAP54372.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Rsm22 PF09243.5 OAP54374.1 - 1e-28 100.1 0.0 1.4e-13 50.4 0.0 3.8 3 1 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 DUF1010 PF06231.6 OAP54374.1 - 0.05 13.5 0.2 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) NodS PF05401.6 OAP54374.1 - 0.23 10.8 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) NIPSNAP PF07978.8 OAP54375.1 - 4.7e-33 113.2 0.2 2e-26 91.9 0.0 2.4 2 0 0 2 2 2 2 NIPSNAP Pyridox_oxidase PF01243.15 OAP54376.1 - 4.5e-10 39.3 0.0 9.4e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 OAP54376.1 - 1.9e-06 27.7 0.5 2.8e-06 27.2 0.3 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 OAP54376.1 - 0.0023 18.1 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ras PF00071.17 OAP54377.1 - 3.8e-54 182.4 0.0 4.4e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP54377.1 - 1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP54377.1 - 8.8e-08 31.5 0.0 1.4e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAP54377.1 - 0.0054 15.8 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 OAP54377.1 - 0.056 12.1 0.0 0.078 11.6 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.5 OAP54377.1 - 0.058 12.6 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 OAP54377.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 OAP54377.1 - 0.14 11.6 0.0 1.4 8.4 0.0 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SpvB PF03534.8 OAP54379.1 - 0.061 12.3 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein HEM4 PF02602.10 OAP54379.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD FAD_binding_3 PF01494.14 OAP54380.1 - 2.8e-23 82.5 0.7 3.2e-22 79.0 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP54380.1 - 1.3e-08 34.2 0.0 2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 OAP54380.1 - 3e-06 26.3 9.3 5.3e-05 22.2 3.1 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP54380.1 - 1.3e-05 25.1 1.0 2.8e-05 24.0 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 OAP54380.1 - 0.00033 19.4 0.7 0.05 12.2 0.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 OAP54380.1 - 0.00034 20.9 0.4 0.00098 19.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP54380.1 - 0.0015 18.4 2.5 0.0069 16.2 1.7 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP54380.1 - 0.002 17.0 0.6 0.003 16.4 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP54380.1 - 0.0035 17.4 0.0 0.0069 16.4 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP54380.1 - 0.007 15.4 3.3 0.011 14.8 0.6 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 OAP54380.1 - 0.038 12.8 0.1 0.051 12.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 OAP54380.1 - 0.039 13.4 0.4 0.068 12.6 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 OAP54380.1 - 0.039 13.3 0.1 0.057 12.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 OAP54380.1 - 0.047 13.2 0.2 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 OAP54380.1 - 0.051 13.2 0.7 0.098 12.3 0.5 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.4 OAP54380.1 - 0.065 12.9 0.3 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.13 OAP54380.1 - 0.068 12.8 0.5 0.13 11.8 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 OAP54380.1 - 0.088 12.8 0.1 0.27 11.2 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain Amino_oxidase PF01593.19 OAP54380.1 - 0.16 10.9 3.1 3.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase HI0933_like PF03486.9 OAP54380.1 - 0.31 9.4 4.7 0.22 9.9 1.8 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 OAP54380.1 - 0.57 9.9 2.2 3.5 7.3 1.5 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding Aldedh PF00171.17 OAP54381.1 - 1.2e-120 402.9 1.7 1.5e-120 402.7 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 OAP54381.1 - 0.004 16.4 0.0 0.0081 15.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) ADH_N PF08240.7 OAP54382.1 - 1.5e-24 85.8 2.0 2.9e-24 84.9 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP54382.1 - 3.1e-21 75.2 0.0 5.3e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP54382.1 - 5.7e-06 27.2 0.0 1.1e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4262 PF14081.1 OAP54382.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) Fungal_trans PF04082.13 OAP54383.1 - 3.5e-37 127.6 1.1 5e-37 127.1 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54383.1 - 3.1e-09 36.5 4.6 5.6e-09 35.7 3.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SecG PF03840.9 OAP54383.1 - 0.26 11.0 1.8 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Aldedh PF00171.17 OAP54384.1 - 7.3e-143 476.2 0.0 8.2e-143 476.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.17 OAP54385.1 - 4.9e-72 242.9 0.0 6.3e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 OAP54386.1 - 3.3e-22 78.6 41.7 3.3e-22 78.6 28.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Toxin_51 PF15531.1 OAP54386.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 51 Lactamase_B PF00753.22 OAP54387.1 - 3.7e-08 33.2 1.9 4.6e-08 32.9 1.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP54387.1 - 1.2e-06 28.2 0.1 2e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP54387.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Aldo_ket_red PF00248.16 OAP54388.1 - 6.2e-57 192.5 0.0 7e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAA_hydrolase PF01557.13 OAP54389.1 - 2.9e-60 203.4 0.0 3.8e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GFA PF04828.9 OAP54390.1 - 9.9e-16 57.4 0.5 1.2e-15 57.1 0.3 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3279 PF11682.3 OAP54390.1 - 0.015 14.8 0.3 0.088 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3279) Zn_ribbon_recom PF13408.1 OAP54390.1 - 0.23 11.7 3.1 0.34 11.1 0.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2757 PF10955.3 OAP54390.1 - 2.2 8.5 5.1 10 6.4 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) Cupin_2 PF07883.6 OAP54391.1 - 9.1e-16 57.1 0.4 5.5e-12 45.0 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 OAP54391.1 - 0.008 15.6 0.0 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 Cupin Auxin_BP PF02041.11 OAP54391.1 - 0.019 14.3 0.0 6.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Auxin binding protein Aldolase_II PF00596.16 OAP54392.1 - 5e-28 97.9 0.3 7e-28 97.4 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain adh_short PF00106.20 OAP54393.1 - 1.6e-15 57.4 0.0 1.8e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54393.1 - 5.7e-08 32.8 0.0 8.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54393.1 - 1.4e-06 28.1 0.1 3.7e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 OAP54393.1 - 0.00026 21.0 0.3 0.0021 18.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.8 OAP54393.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Ribosomal_L6 PF00347.18 OAP54394.1 - 5.4e-24 84.4 7.3 1.4e-12 47.8 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 ATP_bind_1 PF03029.12 OAP54395.1 - 1.7e-78 263.4 0.0 3.3e-78 262.5 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 OAP54395.1 - 1.4e-06 27.2 0.1 0.0013 17.5 0.0 2.4 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 OAP54395.1 - 3.3e-06 26.6 0.1 0.00022 20.7 0.1 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAP54395.1 - 4.3e-05 23.6 0.0 0.00016 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 OAP54395.1 - 0.0001 21.9 0.3 0.13 11.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 OAP54395.1 - 0.00019 20.9 0.1 0.0047 16.4 0.0 2.7 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 OAP54395.1 - 0.00077 19.1 0.5 0.0061 16.2 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 OAP54395.1 - 0.00082 19.3 0.0 0.003 17.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.17 OAP54395.1 - 0.0011 18.4 0.1 0.0053 16.2 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 OAP54395.1 - 0.0021 17.9 0.3 0.0079 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 OAP54395.1 - 0.0023 17.5 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 OAP54395.1 - 0.0038 18.0 0.0 0.0038 18.0 0.0 2.7 2 1 0 2 2 1 1 AAA domain NB-ARC PF00931.17 OAP54395.1 - 0.0047 15.8 0.0 0.013 14.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain FeoB_N PF02421.13 OAP54395.1 - 0.0049 16.1 0.0 0.14 11.3 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B G-alpha PF00503.15 OAP54395.1 - 0.0067 15.1 0.6 1.4 7.5 0.0 3.1 3 0 0 3 3 3 1 G-protein alpha subunit AAA_30 PF13604.1 OAP54395.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 OAP54395.1 - 0.0074 16.7 0.0 4.4 7.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 OAP54395.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 OAP54395.1 - 0.02 14.3 0.0 0.46 9.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 OAP54395.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 OAP54395.1 - 0.05 12.8 0.0 7.8 5.7 0.0 2.9 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_10 PF12846.2 OAP54395.1 - 0.055 12.8 4.2 0.38 10.1 2.9 2.2 1 1 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 OAP54395.1 - 0.058 13.0 3.1 0.44 10.2 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase CbiA PF01656.18 OAP54395.1 - 0.07 12.5 0.1 0.37 10.1 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 OAP54395.1 - 0.77 10.0 7.2 1.2 9.4 0.0 3.2 3 1 0 3 3 3 0 AAA domain Aa_trans PF01490.13 OAP54396.1 - 3.3e-22 78.5 34.0 4.9e-22 77.9 23.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CwfJ_C_1 PF04677.10 OAP54397.1 - 2.1e-28 98.3 0.0 3.9e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 OAP54397.1 - 2.3e-25 88.9 0.0 2.3e-25 88.9 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.4 OAP54397.1 - 0.13 12.3 0.3 6.2 6.9 0.1 2.6 2 0 0 2 2 2 0 Fumarase C C-terminus 2-oxoacid_dh PF00198.18 OAP54398.1 - 1.4e-74 250.2 0.9 2.2e-74 249.6 0.6 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAP54398.1 - 6.6e-19 67.3 0.5 1.4e-18 66.2 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 OAP54398.1 - 4.7e-14 51.7 0.2 9.6e-14 50.7 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain SspB PF04386.8 OAP54398.1 - 0.023 14.2 0.6 0.044 13.3 0.4 1.4 1 0 0 1 1 1 0 Stringent starvation protein B DUF1280 PF06918.9 OAP54398.1 - 0.039 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) Mito_fiss_reg PF05308.6 OAP54398.1 - 0.22 10.8 7.0 0.4 10.0 4.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF605 PF04652.11 OAP54398.1 - 0.28 10.5 9.2 0.42 9.9 6.3 1.2 1 0 0 1 1 1 0 Vta1 like DUF2360 PF10152.4 OAP54398.1 - 0.93 9.7 4.9 1.9 8.7 2.9 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MCPVI PF02993.9 OAP54398.1 - 7.7 6.5 8.5 5 7.2 2.7 2.4 2 0 0 2 2 2 0 Minor capsid protein VI PI-PLC-X PF00388.14 OAP54399.1 - 4.6e-11 42.3 0.0 6.9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SLAC1 PF03595.12 OAP54400.1 - 5.5e-72 242.2 46.2 6.1e-72 242.0 32.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel NAD_binding_10 PF13460.1 OAP54401.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Rrn6 PF10214.4 OAP54402.1 - 2.2e-60 204.7 9.1 6.3e-51 173.3 0.2 2.3 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor DIOX_N PF14226.1 OAP54404.1 - 3.6e-22 79.0 0.1 8.7e-22 77.8 0.1 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP54404.1 - 1.4e-18 66.9 0.0 2.5e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 OAP54405.1 - 1.9e-28 98.9 0.0 4.1e-28 97.9 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_15 PF00723.16 OAP54406.1 - 1.3e-72 244.8 0.0 1.5e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 OAP54406.1 - 3.9e-13 48.8 0.1 7.2e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Aldo_ket_red PF00248.16 OAP54407.1 - 5.6e-68 228.8 0.0 6.8e-67 225.2 0.0 1.9 2 0 0 2 2 2 2 Aldo/keto reductase family zinc_ribbon_6 PF14599.1 OAP54408.1 - 1.1e-26 92.3 1.5 1.1e-26 92.3 1.0 3.7 3 2 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 OAP54408.1 - 2e-15 56.6 21.6 2e-15 56.6 15.0 3.8 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 OAP54408.1 - 1.8e-09 37.2 9.5 1.8e-09 37.2 6.6 5.1 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAP54408.1 - 3.4e-07 29.8 9.1 3.4e-07 29.8 6.3 5.8 3 2 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP54408.1 - 5.1e-07 29.6 7.9 5.1e-07 29.6 5.5 5.6 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 OAP54408.1 - 0.16 12.3 0.1 0.16 12.3 0.1 6.3 7 0 0 7 7 7 0 C2H2-type zinc finger Acyl_transf_1 PF00698.16 OAP54409.1 - 6.2e-22 78.3 0.0 2.8e-15 56.4 0.0 2.1 1 1 0 2 2 2 2 Acyl transferase domain Git3 PF11710.3 OAP54410.1 - 2.1e-23 82.9 15.0 7.4e-23 81.1 10.4 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 OAP54410.1 - 4.2e-11 42.4 9.0 6.5e-11 41.8 6.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 OAP54410.1 - 6.6e-06 25.8 0.6 6.6e-06 25.8 0.4 2.1 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 OAP54410.1 - 0.00093 18.1 10.0 0.00093 18.1 6.9 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor DUF3311 PF11755.3 OAP54410.1 - 0.69 9.4 0.0 0.69 9.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3311) FAD_binding_3 PF01494.14 OAP54411.1 - 7.1e-82 275.2 0.0 9.3e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP54411.1 - 3.5e-06 26.1 0.2 0.0016 17.4 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP54411.1 - 3.6e-05 23.7 0.2 0.00011 22.1 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP54411.1 - 4.3e-05 23.8 0.0 0.022 15.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP54411.1 - 0.00021 21.2 0.1 0.00073 19.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP54411.1 - 0.0004 19.4 0.3 0.0017 17.3 0.1 2.1 2 1 1 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 OAP54411.1 - 0.00072 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAP54411.1 - 0.0013 17.7 0.1 0.02 13.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP54411.1 - 0.052 13.6 0.1 0.44 10.5 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 OAP54411.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.17 OAP54411.1 - 0.19 10.5 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AFG1_ATPase PF03969.11 OAP54414.1 - 1.6e-55 188.4 0.5 1e-24 87.0 0.0 4.9 4 1 1 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.1 OAP54414.1 - 0.003 17.5 0.1 0.027 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP54414.1 - 0.016 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAP54414.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 OAP54414.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 OAP54414.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Bac_DnaA PF00308.13 OAP54414.1 - 0.24 11.0 0.0 59 3.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial dnaA protein APS_kinase PF01583.15 OAP54415.1 - 6.1e-68 227.4 0.0 7.6e-68 227.1 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 OAP54415.1 - 6.1e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP54415.1 - 3.1e-05 24.7 0.0 4.1e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP54415.1 - 6.5e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAP54415.1 - 0.0037 16.7 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 OAP54415.1 - 0.0047 16.1 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_23 PF13476.1 OAP54415.1 - 0.034 14.4 0.1 0.059 13.6 0.0 1.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 OAP54415.1 - 0.039 13.0 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.7 OAP54415.1 - 0.061 12.9 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein UPF0029 PF01205.14 OAP54417.1 - 2.4e-16 59.3 0.0 1.2e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 DUF1180 PF06679.7 OAP54417.1 - 0.0071 16.2 6.8 0.79 9.5 2.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1180) Mucin PF01456.12 OAP54417.1 - 1.4 8.6 24.1 4.6 7.0 11.5 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein DUF3408 PF11888.3 OAP54417.1 - 5 7.0 6.9 9.1 6.2 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Ring_hydroxyl_A PF00848.14 OAP54418.1 - 2.2e-27 96.0 0.1 2.4e-26 92.6 0.1 2.0 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 OAP54419.1 - 2.7e-18 65.3 0.2 5e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 OAP54419.1 - 0.0017 18.0 0.3 0.049 13.2 0.0 2.3 1 1 1 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) PUA PF01472.15 OAP54420.1 - 8.9e-14 50.9 0.3 1.4e-13 50.3 0.2 1.3 1 0 0 1 1 1 1 PUA domain La PF05383.12 OAP54421.1 - 5.3e-20 70.9 0.1 9.9e-20 70.1 0.1 1.4 1 0 0 1 1 1 1 La domain NPR3 PF03666.8 OAP54422.1 - 1.2e-125 419.6 0.0 1.2e-125 419.6 0.0 2.0 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 peroxidase PF00141.18 OAP54423.1 - 4.9e-46 157.0 0.0 7e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MFS_1 PF07690.11 OAP54425.1 - 2e-33 115.5 50.1 4.8e-33 114.3 34.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MARVEL PF01284.18 OAP54426.1 - 0.0023 17.7 18.2 0.0048 16.7 12.1 1.8 1 1 1 2 2 2 1 Membrane-associating domain DUF3816 PF12822.2 OAP54426.1 - 2 8.2 9.7 2.8 7.8 6.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) CD20 PF04103.10 OAP54426.1 - 2.5 8.0 7.6 6.1 6.7 5.4 1.6 1 1 0 1 1 1 0 CD20-like family Ribosomal_60s PF00428.14 OAP54426.1 - 5.9 7.3 7.9 11 6.4 5.5 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein Aldo_ket_red PF00248.16 OAP54427.1 - 2.1e-59 200.6 0.0 2.4e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAP2 PF01569.16 OAP54428.1 - 1.8e-22 79.4 1.4 3.6e-22 78.4 0.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily Aminotran_4 PF01063.14 OAP54432.1 - 4.3e-37 127.7 0.0 5.3e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF1469 PF07332.6 OAP54433.1 - 0.14 11.8 4.2 5 6.8 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Sulfatase PF00884.18 OAP54436.1 - 2.4e-55 187.9 2.5 3.3e-55 187.4 1.7 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 OAP54436.1 - 0.00033 20.0 0.4 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase WD40 PF00400.27 OAP54437.1 - 8.3e-27 92.0 14.2 1.5e-08 34.1 0.5 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 OAP54437.1 - 1.1e-06 28.4 0.0 0.0011 18.7 0.0 2.9 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAP54437.1 - 2.4e-05 22.8 0.0 0.00039 18.8 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 OAP54437.1 - 0.01 14.6 0.0 0.65 8.7 0.0 2.3 1 1 0 2 2 2 0 Coatomer WD associated region PD40 PF07676.7 OAP54437.1 - 0.016 14.8 2.6 1.6 8.4 0.6 3.9 4 1 0 4 4 4 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 OAP54437.1 - 0.036 13.7 5.1 0.14 11.8 0.4 2.9 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 OAP54437.1 - 0.19 9.4 0.9 1.2 6.8 0.1 2.3 2 1 0 2 2 2 0 IKI3 family Fungal_trans PF04082.13 OAP54438.1 - 2.2e-22 79.1 0.2 4e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54438.1 - 2.9e-09 36.6 12.5 5.7e-09 35.7 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 OAP54439.1 - 4.7e-54 183.1 0.0 5.6e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UDPGT PF00201.13 OAP54439.1 - 0.015 13.8 0.0 0.02 13.4 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Nefa_Nip30_N PF10187.4 OAP54440.1 - 5e-29 100.4 4.2 5e-29 100.4 2.9 2.2 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 OAP54440.1 - 0.0024 16.8 1.6 0.003 16.5 1.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SMN PF06003.7 OAP54442.1 - 0.00025 20.2 13.3 0.0014 17.7 1.3 2.9 1 1 2 3 3 3 3 Survival motor neuron protein (SMN) V-ATPase_C PF03223.10 OAP54443.1 - 3.2e-116 388.3 0.1 3.5e-116 388.1 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C peroxidase PF00141.18 OAP54444.1 - 8.1e-89 297.0 0.0 2e-46 158.3 0.0 2.4 2 0 0 2 2 2 2 Peroxidase 4HBT PF03061.17 OAP54445.1 - 1.1e-10 41.5 0.0 2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily E1-E2_ATPase PF00122.15 OAP54446.1 - 2e-63 213.4 1.0 4e-63 212.5 0.7 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAP54446.1 - 8.8e-46 155.7 8.6 8.8e-46 155.7 6.0 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAP54446.1 - 2e-29 103.5 0.2 9.6e-29 101.3 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP54446.1 - 7e-20 70.7 0.0 1.4e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAP54446.1 - 4.6e-13 49.7 0.0 1e-12 48.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAP54446.1 - 1.8e-08 33.7 0.2 8.1e-08 31.6 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAP54446.1 - 1.3e-05 24.8 0.8 3.6e-05 23.4 0.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1772 PF08592.6 OAP54446.1 - 0.061 13.0 0.0 0.061 13.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF3325 PF11804.3 OAP54446.1 - 0.096 12.6 2.0 0.19 11.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) HD PF01966.17 OAP54447.1 - 0.0032 17.4 0.0 0.0054 16.7 0.0 1.5 1 1 0 1 1 1 1 HD domain Nup84_Nup100 PF04121.8 OAP54448.1 - 2.7e-45 154.2 12.2 3.2e-38 130.9 5.0 3.4 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 PvlArgDC PF01862.11 OAP54449.1 - 0.23 11.0 0.9 0.42 10.2 0.6 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) DUF605 PF04652.11 OAP54449.1 - 4 6.7 9.8 4.9 6.4 6.8 1.1 1 0 0 1 1 1 0 Vta1 like Ligase_CoA PF00549.14 OAP54450.1 - 2.2e-33 114.9 2.1 1.1e-15 57.5 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 OAP54450.1 - 6.5e-12 45.7 1.4 1.6e-11 44.5 0.1 2.4 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 OAP54450.1 - 1.2e-08 34.7 0.4 5.9e-06 25.9 0.0 2.7 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain DUF2236 PF09995.4 OAP54451.1 - 0.086 12.1 0.0 0.27 10.4 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Aldedh PF00171.17 OAP54452.1 - 2.7e-110 368.8 0.0 3.3e-110 368.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.20 OAP54453.1 - 1.6e-69 234.0 0.0 2.6e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAP54453.1 - 1.8e-49 166.9 0.2 3.1e-49 166.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAP54453.1 - 2.1e-05 24.5 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAP54453.1 - 0.0037 16.7 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Rad60-SLD PF11976.3 OAP54454.1 - 3e-20 71.6 0.2 3.8e-20 71.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAP54454.1 - 6.7e-09 35.0 0.1 8.2e-09 34.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family 14-3-3 PF00244.15 OAP54455.1 - 2.8e-09 36.4 0.0 1.6e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 14-3-3 protein LsmAD PF06741.8 OAP54456.1 - 8.8e-27 93.0 4.6 1.9e-26 91.9 3.2 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 OAP54456.1 - 2.3e-09 37.0 0.0 4.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.20 OAP54457.1 - 4.2e-77 258.8 0.0 6.2e-77 258.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54457.1 - 2.2e-39 135.0 0.0 3.4e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 OAP54457.1 - 3.4e-13 48.7 0.1 5.5e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 OAP54457.1 - 2.8e-06 26.5 0.0 5.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAP54457.1 - 9.3e-06 24.7 0.0 6.9e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAP54457.1 - 0.0009 19.0 0.6 0.027 14.1 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 OAP54457.1 - 0.0099 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 OAP54457.1 - 0.072 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 OAP54457.1 - 0.089 11.9 0.1 0.49 9.5 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1604 PF07713.8 OAP54458.1 - 3.3e-39 132.5 2.1 7.9e-39 131.3 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 OAP54458.1 - 4.5e-07 29.5 0.2 3e-06 26.9 0.1 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 OAP54458.1 - 0.0022 17.8 0.2 0.011 15.5 0.2 2.3 1 1 0 1 1 1 1 DExH-box splicing factor binding site DUF479 PF04336.7 OAP54458.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF479 UAA PF08449.6 OAP54459.1 - 1.7e-74 250.4 8.7 2.6e-74 249.8 6.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 OAP54459.1 - 4.5e-07 29.9 6.2 4.5e-07 29.9 4.3 3.3 3 0 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 OAP54459.1 - 1.9e-06 27.6 2.6 1.9e-06 27.6 1.8 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 OAP54459.1 - 3.5e-05 23.0 0.4 0.071 12.2 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 OAP54459.1 - 0.0035 17.5 6.7 0.0035 17.5 4.7 3.6 2 2 2 4 4 4 2 Multidrug resistance efflux transporter TPR_12 PF13424.1 OAP54460.1 - 5.2e-06 26.3 0.5 0.0012 18.7 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAP54460.1 - 1.5e-05 24.7 0.1 0.0012 18.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAP54460.1 - 3.1e-05 23.9 0.4 0.0074 16.6 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP54460.1 - 3.3e-05 24.1 0.3 0.056 14.0 0.0 4.5 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP54460.1 - 0.00056 20.1 0.1 0.049 13.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP54460.1 - 0.0069 16.2 0.1 0.094 12.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP54460.1 - 0.0094 15.6 0.4 0.22 11.4 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP54460.1 - 0.019 15.6 1.4 0.31 11.7 0.0 3.5 3 2 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 OAP54460.1 - 0.043 13.9 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 OAP54460.1 - 0.081 12.7 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pam16 PF03656.8 OAP54460.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Pam16 TPR_6 PF13174.1 OAP54460.1 - 0.14 12.6 0.8 0.52 10.8 0.2 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat Gryzun PF07919.7 OAP54461.1 - 7.2e-76 255.6 0.0 1e-75 255.1 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 OAP54461.1 - 7.7e-67 225.3 0.4 3.1e-62 210.2 0.5 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 PEMT PF04191.8 OAP54462.1 - 1.7e-30 105.2 2.2 1.7e-30 105.2 1.5 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase RXT2_N PF08595.6 OAP54463.1 - 2e-34 118.5 0.0 2e-34 118.5 0.0 2.8 2 1 1 3 3 3 1 RXT2-like, N-terminal CK_II_beta PF01214.13 OAP54464.1 - 3.3e-73 245.1 0.1 4.9e-73 244.5 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Apc5 PF12862.2 OAP54464.1 - 0.044 13.6 0.2 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 MFS_1 PF07690.11 OAP54466.1 - 6.2e-30 104.1 27.8 6.2e-30 104.1 19.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribonuc_P_40 PF08584.6 OAP54467.1 - 1.6e-66 224.1 0.0 2.2e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Pet191_N PF10203.4 OAP54468.1 - 0.015 15.2 1.8 1.1 9.3 0.7 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 OAP54468.1 - 0.029 14.3 1.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 OAP54468.1 - 0.097 12.6 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 CHCH domain BPL_LplA_LipB PF03099.14 OAP54471.1 - 6.3e-08 32.6 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Peptidase_C65 PF10275.4 OAP54472.1 - 4e-62 209.7 0.0 5.1e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.22 OAP54473.1 - 1.5e-22 79.8 0.6 4.9e-22 78.2 0.5 1.9 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 OAP54473.1 - 6e-08 32.5 0.2 1.5e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 OAP54473.1 - 0.0035 17.2 3.1 0.81 9.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP54473.1 - 0.0041 16.7 0.7 0.34 10.8 0.1 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAP54473.1 - 0.0058 16.5 0.1 0.36 10.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP54473.1 - 0.006 16.2 5.7 0.31 10.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP54473.1 - 0.0087 15.9 4.0 0.11 12.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat HTH_9 PF08221.6 OAP54473.1 - 0.062 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain SNAP PF14938.1 OAP54473.1 - 0.19 10.8 5.4 0.53 9.3 1.9 2.7 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_1 PF00515.23 OAP54473.1 - 2.1 8.1 8.3 0.26 10.9 0.2 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat CWC25 PF12542.3 OAP54474.1 - 2.1e-27 95.3 2.0 2.1e-27 95.3 1.4 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.4 OAP54474.1 - 2.6e-13 49.7 10.6 2.6e-13 49.7 7.4 2.2 1 1 1 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 OAP54474.1 - 0.35 10.2 0.1 0.35 10.2 0.1 1.9 2 0 0 2 2 2 0 RNA dependent RNA polymerase Ank_2 PF12796.2 OAP54476.1 - 9.1e-42 141.3 0.1 1e-23 83.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAP54476.1 - 6.8e-30 101.3 0.0 6e-09 35.2 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 OAP54476.1 - 3.5e-22 76.2 1.2 1.2e-05 25.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 OAP54476.1 - 4.7e-21 74.7 0.1 1.1e-11 44.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP54476.1 - 9.8e-16 57.4 0.8 0.00019 21.5 0.0 4.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.7 OAP54476.1 - 1.9e-08 34.1 0.0 4.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain SpoU_sub_bind PF08032.7 OAP54476.1 - 0.016 15.3 0.2 32 4.7 0.1 3.9 3 1 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Uds1 PF15456.1 OAP54477.1 - 0.058 13.3 0.3 0.23 11.4 0.2 1.8 2 0 0 2 2 2 0 Up-regulated During Septation DUF1864 PF08933.6 OAP54477.1 - 0.06 11.8 0.1 0.076 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Amidase PF01425.16 OAP54478.1 - 1.4e-43 149.4 0.0 1e-36 126.7 0.0 2.1 2 0 0 2 2 2 2 Amidase WD40 PF00400.27 OAP54479.1 - 5.3e-22 76.8 0.0 1.3e-14 53.4 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.7 OAP54479.1 - 9.7e-08 31.8 0.0 2.7e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP54479.1 - 1.8e-06 28.1 0.4 2.5e-05 24.3 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP54479.1 - 0.0021 18.2 0.1 0.011 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAP54479.1 - 0.0027 18.5 0.2 0.03 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 OAP54479.1 - 0.011 14.6 0.0 0.035 12.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 OAP54479.1 - 0.011 15.4 0.0 0.04 13.6 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Rpn3_C PF08375.6 OAP54479.1 - 0.012 16.0 13.2 0.13 12.6 9.9 2.1 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal APS_kinase PF01583.15 OAP54479.1 - 0.03 14.0 0.1 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_23 PF13476.1 OAP54479.1 - 0.044 14.1 6.3 0.8 10.0 2.9 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 OAP54479.1 - 0.051 13.7 0.2 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CDC45 PF02724.9 OAP54479.1 - 0.063 11.3 15.5 0.094 10.7 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein PIF1 PF05970.9 OAP54479.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 OAP54479.1 - 0.21 11.7 0.0 0.68 10.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Zip PF02535.17 OAP54479.1 - 0.42 9.5 4.6 0.1 11.5 1.1 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter Nop14 PF04147.7 OAP54479.1 - 0.46 8.3 21.2 0.72 7.7 14.7 1.3 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.12 OAP54479.1 - 0.53 10.0 6.1 0.87 9.3 4.2 1.2 1 0 0 1 1 1 0 DDHD domain NOA36 PF06524.7 OAP54479.1 - 0.94 8.6 11.6 1.4 8.0 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein eIF-3c_N PF05470.7 OAP54479.1 - 0.95 7.4 7.6 1.4 6.9 5.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AAA_18 PF13238.1 OAP54479.1 - 1.7 8.9 9.0 0.39 11.0 0.1 3.0 2 0 0 2 2 2 0 AAA domain TLP-20 PF06088.6 OAP54479.1 - 3.2 7.3 7.1 5.6 6.6 4.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.8 OAP54479.1 - 3.4 7.2 20.7 6.8 6.2 14.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Prog_receptor PF02161.10 OAP54479.1 - 4.8 5.8 8.6 6.8 5.3 6.0 1.1 1 0 0 1 1 1 0 Progesterone receptor Trypan_PARP PF05887.6 OAP54479.1 - 6.6 6.5 21.6 11 5.8 15.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.7 OAP54479.1 - 7.9 5.6 20.9 11 5.1 14.5 1.1 1 0 0 1 1 1 0 SDA1 DUF2001 PF09393.5 OAP54480.1 - 0.017 14.7 0.2 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2001) NMD3 PF04981.8 OAP54480.1 - 0.044 12.8 2.9 0.096 11.7 2.0 1.6 1 0 0 1 1 1 0 NMD3 family PTR2 PF00854.16 OAP54481.1 - 2.8e-39 134.9 18.8 5e-38 130.8 13.0 2.6 1 1 0 1 1 1 1 POT family DUF4149 PF13664.1 OAP54481.1 - 0.45 10.5 6.5 7.8 6.6 0.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Ldh_1_C PF02866.13 OAP54482.1 - 1.9e-27 96.0 0.0 2.5e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 OAP54482.1 - 1.6e-09 37.7 0.0 2.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain FAA_hydrolase PF01557.13 OAP54482.1 - 0.043 13.2 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans_2 PF11951.3 OAP54483.1 - 7.4e-14 51.1 0.1 3.7e-13 48.8 0.1 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Amino_oxidase PF01593.19 OAP54484.1 - 1.4e-47 162.8 0.6 5e-47 161.0 0.4 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 OAP54484.1 - 1.9e-13 50.0 0.0 1.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP54484.1 - 7.3e-11 41.9 0.1 1.6e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 OAP54484.1 - 2.2e-07 30.3 0.0 8e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP54484.1 - 5.8e-07 28.8 0.0 9.6e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAP54484.1 - 2e-05 23.6 0.0 3.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP54484.1 - 0.00033 20.5 0.0 0.0034 17.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP54484.1 - 0.00066 18.2 0.0 0.0037 15.7 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 OAP54484.1 - 0.00083 19.4 0.0 0.089 12.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP54484.1 - 0.0013 19.0 0.0 0.027 14.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP54484.1 - 0.0024 16.8 0.0 0.0072 15.2 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAP54484.1 - 0.011 14.7 0.0 0.042 12.7 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 OAP54484.1 - 0.031 13.3 0.5 0.058 12.4 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 OAP54484.1 - 0.051 13.3 0.1 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding AA_permease_2 PF13520.1 OAP54485.1 - 9.5e-44 149.5 49.6 1.2e-43 149.2 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP54485.1 - 4.5e-18 64.8 45.8 5.9e-18 64.4 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.23 OAP54486.1 - 8.8e-46 156.1 0.0 1.4e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 OAP54486.1 - 2.9e-13 49.2 0.1 5e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding_C PF13193.1 OAP54486.1 - 0.00013 22.8 0.0 0.00041 21.2 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 OAP54486.1 - 0.12 12.2 2.4 0.25 11.2 1.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 OAP54487.1 - 2.5e-18 66.6 0.2 1.1e-17 64.5 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP54487.1 - 0.00071 19.0 0.0 1.3 8.6 0.0 2.8 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, middle domain 4HBT_3 PF13622.1 OAP54488.1 - 8e-20 71.6 1.3 8.7e-20 71.5 0.9 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAP54488.1 - 0.0017 18.0 0.1 0.0022 17.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA thioesterase ACOX PF01756.14 OAP54489.1 - 4.3e-39 133.8 0.2 1e-38 132.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 OAP54489.1 - 9.7e-28 96.9 0.2 2.1e-27 95.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAP54489.1 - 1.2e-11 43.9 1.7 1.9e-11 43.2 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 OAP54489.1 - 0.00013 22.1 0.0 0.0042 17.2 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DAGK_cat PF00781.19 OAP54490.1 - 2e-21 75.7 0.1 4e-21 74.7 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.20 OAP54491.1 - 9e-67 224.9 0.0 1.4e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54491.1 - 2.1e-35 122.0 0.0 8e-35 120.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP54491.1 - 1.7e-06 27.1 0.0 4.6e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 OAP54491.1 - 0.00094 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAP54491.1 - 0.0073 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Ammonium_transp PF00909.16 OAP54492.1 - 3e-119 398.0 32.4 3.4e-119 397.8 22.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Kelch_5 PF13854.1 OAP54494.1 - 7.9e-12 44.8 0.6 7.9e-12 44.8 0.4 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 OAP54494.1 - 4.1e-09 36.3 4.5 0.0062 16.6 0.2 4.2 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF4448 PF14610.1 OAP54494.1 - 0.00043 19.8 0.1 0.0009 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ATP1G1_PLM_MAT8 PF02038.11 OAP54494.1 - 0.06 12.3 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Alpha_GJ PF03229.8 OAP54494.1 - 0.1 12.9 2.4 0.12 12.7 0.2 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J Prominin PF05478.6 OAP54494.1 - 0.25 8.8 0.0 0.33 8.4 0.0 1.1 1 0 0 1 1 1 0 Prominin Kelch_1 PF01344.20 OAP54494.1 - 4 7.0 9.2 7 6.2 0.3 3.6 3 1 0 3 3 3 0 Kelch motif RRM_1 PF00076.17 OAP54495.1 - 4.1e-15 55.1 0.2 2.5e-06 26.9 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP54495.1 - 7.6e-14 51.4 0.1 9.7e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP54495.1 - 2e-12 46.7 0.1 6.7e-09 35.4 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.13 OAP54497.1 - 7.2e-06 25.4 9.2 2.4e-05 23.7 6.3 1.9 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Mpv17_PMP22 PF04117.7 OAP54498.1 - 1.5e-23 82.1 0.1 3.2e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family RTX PF02382.10 OAP54498.1 - 0.073 11.3 0.2 0.087 11.0 0.1 1.0 1 0 0 1 1 1 0 RTX N-terminal domain PGK PF00162.14 OAP54499.1 - 3.4e-151 503.1 0.3 3.8e-151 503.0 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.6 OAP54499.1 - 0.06 12.7 0.6 1.5 8.1 0.1 2.8 3 0 0 3 3 3 0 Propionate catabolism activator Acetyltransf_CG PF14542.1 OAP54499.1 - 0.092 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DSS1_SEM1 PF05160.8 OAP54500.1 - 5.5e-25 86.9 11.4 7.8e-25 86.4 7.9 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Remorin_N PF03766.8 OAP54500.1 - 0.081 12.7 0.6 0.18 11.6 0.4 1.6 1 0 0 1 1 1 0 Remorin, N-terminal region M-inducer_phosp PF06617.8 OAP54500.1 - 0.16 11.0 2.2 0.16 11.0 1.5 1.2 1 0 0 1 1 1 0 M-phase inducer phosphatase DUF3808 PF10300.4 OAP54501.1 - 2.4e-131 438.5 0.0 3.4e-131 438.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Acetyltransf_1 PF00583.19 OAP54502.1 - 2.2e-12 46.8 0.0 3.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP54502.1 - 3.5e-07 30.2 0.0 5.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP54502.1 - 1.6e-05 25.0 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP54502.1 - 2.7e-05 24.1 0.0 3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP54502.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 OAP54502.1 - 0.003 17.4 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP54502.1 - 0.0044 16.8 0.0 0.0063 16.3 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase ELFV_dehydrog PF00208.16 OAP54503.1 - 2.1e-83 279.6 4.1 2.6e-83 279.3 2.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 OAP54503.1 - 1.3e-48 163.8 0.0 3.2e-48 162.6 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Nup160 PF11715.3 OAP54504.1 - 2.1e-95 319.9 2.1 2.8e-95 319.5 1.4 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_16 PF13432.1 OAP54504.1 - 0.57 10.9 5.8 1.2 9.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP54504.1 - 1.7 8.6 6.3 2 8.4 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat FF PF01846.14 OAP54505.1 - 1.3e-45 153.1 27.2 2e-14 53.2 0.6 6.9 7 0 0 7 7 7 5 FF domain WW PF00397.21 OAP54505.1 - 9.5e-17 60.5 16.3 9.1e-09 35.0 4.0 2.6 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 OAP54506.1 - 3.2e-49 167.9 0.0 4.6e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SIP1 PF04938.7 OAP54508.1 - 0.00017 21.0 0.1 0.00071 19.0 0.0 2.2 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) tRNA-synt_2 PF00152.15 OAP54511.1 - 5.4e-74 248.9 0.2 9.2e-74 248.1 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAP54511.1 - 4.9e-07 29.5 0.1 8.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAP54511.1 - 0.027 13.6 0.3 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) NARP1 PF12569.3 OAP54511.1 - 0.14 10.9 10.7 0.17 10.5 7.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Abhydrolase_5 PF12695.2 OAP54512.1 - 2.3e-06 27.4 0.0 3.4e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP54512.1 - 3.3e-06 27.1 0.6 8.3e-06 25.8 0.4 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 OAP54512.1 - 9.3e-05 21.8 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 OAP54512.1 - 0.00015 21.4 0.0 0.00036 20.2 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 OAP54512.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 OAP54512.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) MRI PF15325.1 OAP54512.1 - 7.1 7.6 8.3 2.5 9.0 0.1 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection PX PF00787.19 OAP54513.1 - 6.2e-15 54.9 0.0 5.9e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 OAP54513.1 - 3.4e-07 29.8 6.9 3.4e-07 29.8 4.8 2.1 2 0 0 2 2 2 1 SNARE domain BCIP PF13862.1 OAP54513.1 - 0.071 12.6 1.5 0.19 11.2 0.2 2.0 2 0 0 2 2 2 0 p21-C-terminal region-binding protein Ku_N PF03731.10 OAP54514.1 - 9.3e-27 93.9 0.1 3.1e-26 92.1 0.0 1.9 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 OAP54514.1 - 1.6e-23 83.1 0.0 3.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 OAP54514.1 - 7.7e-15 54.8 0.0 1.9e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like DUF4149 PF13664.1 OAP54515.1 - 1.6e-24 85.8 1.1 1.6e-24 85.8 0.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1223 PF06764.6 OAP54517.1 - 1.4e-41 142.5 0.0 1.6e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) Thioredoxin_3 PF13192.1 OAP54517.1 - 0.11 12.3 0.0 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain bZIP_1 PF00170.16 OAP54518.1 - 4.6e-06 26.4 11.5 4.6e-06 26.4 8.0 2.8 2 1 1 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.12 OAP54518.1 - 0.00019 21.6 13.3 0.00053 20.2 9.1 1.9 1 1 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 OAP54518.1 - 0.00096 18.9 10.0 0.00096 18.9 6.9 3.0 2 1 1 3 3 3 1 Basic region leucine zipper DUF4316 PF14195.1 OAP54518.1 - 0.94 9.5 6.3 2.8 8.0 4.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Sel1 PF08238.7 OAP54519.1 - 1.6e-19 69.8 3.9 8.4e-07 29.4 0.0 4.2 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.1 OAP54519.1 - 0.036 14.7 2.7 11 6.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.2 OAP54520.1 - 2.5e-07 30.3 0.2 9.5e-07 28.4 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP54520.1 - 9.2e-05 21.9 0.0 0.00027 20.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 OAP54520.1 - 0.15 11.8 0.5 15 5.3 0.0 2.5 1 1 1 2 2 2 0 F-box-like domain p450 PF00067.17 OAP54522.1 - 6.9e-60 202.8 0.0 8.4e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.5 OAP54524.1 - 0.0031 16.7 0.2 0.0055 15.9 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SKG6 PF08693.5 OAP54525.1 - 6.1e-10 38.2 1.8 1.8e-09 36.7 1.2 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 OAP54525.1 - 3.1e-05 23.5 0.0 4.9e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) VSP PF03302.8 OAP54525.1 - 9.6e-05 21.1 4.2 9.6e-05 21.1 2.9 1.5 1 1 1 2 2 2 1 Giardia variant-specific surface protein CD34_antigen PF06365.7 OAP54525.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4231 PF14015.1 OAP54525.1 - 0.44 10.5 2.4 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) TMEM154 PF15102.1 OAP54525.1 - 2.9 7.5 17.5 4e+02 0.6 12.1 3.0 1 1 0 1 1 1 0 TMEM154 protein family PTS_2-RNA PF01885.11 OAP54526.1 - 1.2e-57 194.2 0.0 2e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 OAP54526.1 - 0.18 11.6 0.0 0.71 9.7 0.0 1.9 2 0 0 2 2 2 0 La domain RNA_pol_Rpo13 PF12136.3 OAP54526.1 - 1.1 8.9 9.6 2.5 7.8 6.7 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain Prp31_C PF09785.4 OAP54527.1 - 1.4e-47 161.1 1.0 3.8e-47 159.7 0.7 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 OAP54527.1 - 1.4e-38 131.5 0.1 2.6e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAP54527.1 - 1.6e-21 75.8 0.2 3.7e-21 74.6 0.1 1.7 2 0 0 2 2 2 1 NOSIC (NUC001) domain Nop14 PF04147.7 OAP54527.1 - 6.4 4.5 9.4 9.4 4.0 6.5 1.2 1 0 0 1 1 1 0 Nop14-like family TPR_14 PF13428.1 OAP54528.1 - 1.7e-24 84.0 22.3 0.015 15.9 0.1 12.3 6 2 8 14 14 13 8 Tetratricopeptide repeat TPR_19 PF14559.1 OAP54528.1 - 3.7e-23 81.6 0.1 0.00029 21.1 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat HAT PF02184.11 OAP54528.1 - 1.3e-22 79.2 88.5 3.5e-15 55.4 2.8 14.2 15 1 0 15 15 15 4 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 OAP54528.1 - 3e-21 75.5 13.6 0.018 15.7 0.0 9.1 9 1 0 10 10 9 5 Tetratricopeptide repeat Suf PF05843.9 OAP54528.1 - 8.8e-14 51.8 26.6 0.0029 17.3 0.2 6.5 3 2 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_2 PF07719.12 OAP54528.1 - 2.8e-09 36.1 21.4 0.98 9.5 0.0 10.1 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAP54528.1 - 2.6e-07 30.4 20.3 0.27 11.1 0.0 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAP54528.1 - 4.8e-07 29.3 9.3 0.96 9.1 0.0 7.5 8 1 0 8 8 8 2 TPR repeat TPR_17 PF13431.1 OAP54528.1 - 6.9e-07 28.9 7.1 0.052 13.7 0.0 6.3 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 OAP54528.1 - 3.2e-06 26.4 19.5 0.00089 18.3 3.0 5.4 1 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAP54528.1 - 3.1e-05 23.4 13.8 14 5.7 0.0 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP54528.1 - 3.7e-05 23.8 21.6 2.8 8.5 0.0 8.9 9 0 0 9 9 9 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 OAP54528.1 - 0.00041 20.0 32.5 0.016 14.9 1.7 7.6 6 3 1 8 8 7 2 U3 small nucleolar RNA-associated protein 6 PPTA PF01239.17 OAP54528.1 - 0.013 14.8 1.5 4.1 6.9 0.3 2.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Fis1_TPR_C PF14853.1 OAP54528.1 - 0.025 14.4 13.4 7.4 6.5 0.7 6.1 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 OAP54528.1 - 0.037 13.7 16.3 43 4.2 0.0 8.0 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP54528.1 - 3.3 7.4 13.0 32 4.3 0.0 5.9 8 0 0 8 8 7 0 Tetratricopeptide repeat Kelch_6 PF13964.1 OAP54529.1 - 6.3e-06 26.1 6.4 0.0094 16.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 OAP54529.1 - 0.00072 19.6 0.1 0.00072 19.6 0.1 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 OAP54529.1 - 0.0049 16.8 6.2 0.05 13.5 0.3 3.7 3 0 0 3 3 3 1 Kelch motif Herpes_gE PF02480.11 OAP54529.1 - 0.0086 14.3 0.0 0.015 13.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E 7tm_1 PF00001.16 OAP54529.1 - 0.28 10.2 0.0 0.43 9.6 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Kelch_1 PF01344.20 OAP54529.1 - 0.47 10.0 2.4 19 4.8 0.0 3.2 2 0 0 2 2 2 0 Kelch motif NCKAP5 PF15246.1 OAP54529.1 - 0.5 9.7 4.1 0.22 10.8 0.6 1.9 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein Kelch_2 PF07646.10 OAP54529.1 - 4.9 7.0 9.9 37 4.2 0.0 4.9 5 0 0 5 5 5 0 Kelch motif Stb3 PF10330.4 OAP54530.1 - 7.6e-38 128.1 0.0 1.2e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein ABC_tran PF00005.22 OAP54531.1 - 2.2e-34 118.6 0.0 2.9e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 OAP54531.1 - 1.8e-14 53.0 5.6 1.8e-14 53.0 3.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 OAP54531.1 - 1.1e-13 51.8 7.3 0.006 16.5 0.0 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 OAP54531.1 - 1.8e-11 43.7 2.1 0.0047 16.1 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 OAP54531.1 - 2.7e-07 30.0 0.1 1.9 7.4 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 OAP54531.1 - 2.2e-05 25.2 0.5 0.43 11.4 0.0 3.0 2 2 0 2 2 2 2 AAA domain Fer4 PF00037.22 OAP54531.1 - 4.3e-05 22.9 2.6 4.3e-05 22.9 1.8 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA PF00004.24 OAP54531.1 - 4.5e-05 23.6 0.1 0.063 13.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 OAP54531.1 - 6.6e-05 22.1 1.8 0.27 10.4 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAP54531.1 - 7.2e-05 22.2 0.7 0.061 12.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 OAP54531.1 - 7.7e-05 22.8 0.0 0.028 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAP54531.1 - 0.00026 21.2 0.0 0.45 10.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.10 OAP54531.1 - 0.00029 19.6 0.0 0.058 12.0 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Miro PF08477.8 OAP54531.1 - 0.00087 19.7 0.0 0.06 13.8 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein VirE PF05272.6 OAP54531.1 - 0.0011 18.4 0.2 1.5 8.2 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E AAA_33 PF13671.1 OAP54531.1 - 0.0017 18.2 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 OAP54531.1 - 0.0019 18.0 11.5 0.0036 17.1 7.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain MobB PF03205.9 OAP54531.1 - 0.0021 17.7 1.5 0.22 11.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 OAP54531.1 - 0.0023 18.0 0.7 1 9.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase UPF0079 PF02367.12 OAP54531.1 - 0.0042 16.7 0.4 0.049 13.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 OAP54531.1 - 0.0043 15.5 0.0 0.0043 15.5 0.0 1.8 3 0 0 3 3 1 1 AAA domain SRP54 PF00448.17 OAP54531.1 - 0.0049 16.3 3.6 0.073 12.5 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 OAP54531.1 - 0.0054 16.1 0.2 4 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 OAP54531.1 - 0.0058 16.9 1.1 0.31 11.3 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP54531.1 - 0.016 15.2 0.1 5.8 6.8 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 OAP54531.1 - 0.023 14.3 4.0 0.64 9.6 0.1 2.7 3 0 0 3 3 2 0 NACHT domain AAA_28 PF13521.1 OAP54531.1 - 0.023 14.6 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_6 PF12837.2 OAP54531.1 - 0.028 14.2 11.0 0.069 13.0 1.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.2 OAP54531.1 - 0.03 14.7 1.8 0.03 14.7 1.2 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 OAP54531.1 - 0.04 14.6 0.1 0.04 14.6 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain SbcCD_C PF13558.1 OAP54531.1 - 0.043 13.7 0.1 9.9 6.1 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Thymidylate_kin PF02223.12 OAP54531.1 - 0.053 12.8 0.4 13 5.1 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase PduV-EutP PF10662.4 OAP54531.1 - 0.055 12.9 2.7 0.056 12.9 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 OAP54531.1 - 0.062 13.2 0.1 8.7 6.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 OAP54531.1 - 0.085 11.6 0.2 7.8 5.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 OAP54531.1 - 0.089 11.9 0.2 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 KaiC HflK_N PF12221.3 OAP54531.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Fer4_17 PF13534.1 OAP54531.1 - 0.14 12.5 0.2 0.14 12.5 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 OAP54531.1 - 0.16 11.5 2.2 0.91 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 OAP54531.1 - 0.17 11.4 0.3 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 OAP54531.1 - 0.37 10.8 9.4 0.29 11.1 1.0 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAP54531.1 - 0.58 10.4 13.3 0.048 13.9 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 OAP54531.1 - 0.68 9.6 2.4 24 4.5 0.1 2.6 2 0 0 2 2 2 0 NTPase Fer4_10 PF13237.1 OAP54531.1 - 0.85 9.4 15.5 0.072 12.9 1.2 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 OAP54531.1 - 3.2 7.8 12.4 1.6 8.8 1.6 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.18 OAP54532.1 - 2e-64 217.2 0.0 3.7e-64 216.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 OAP54532.1 - 4.9e-22 77.3 3.5 1.6e-12 46.9 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 OAP54532.1 - 2.1e-13 50.3 0.8 6.5e-13 48.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 OAP54532.1 - 1.5e-12 47.1 0.0 4.4e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LIM PF00412.17 OAP54533.1 - 1.2e-24 86.0 22.3 1.5e-09 37.7 3.8 3.6 3 0 0 3 3 3 3 LIM domain Paired_CXXCH_1 PF09699.5 OAP54533.1 - 0.031 13.7 0.6 0.031 13.7 0.4 2.9 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) MFS_1 PF07690.11 OAP54534.1 - 2.7e-25 88.8 38.9 4.4e-25 88.1 26.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAP54534.1 - 4.2e-05 22.1 6.0 4.2e-05 22.1 4.1 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 OAP54534.1 - 0.036 13.8 3.9 0.14 12.0 0.1 2.6 2 0 0 2 2 2 0 MFS_1 like family HET PF06985.6 OAP54535.1 - 3.8e-08 33.6 0.0 3e-05 24.1 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_transf_90 PF05686.7 OAP54536.1 - 7.7e-36 123.6 0.7 1.4e-35 122.7 0.5 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 OAP54536.1 - 0.0022 18.2 0.1 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PQ-loop PF04193.9 OAP54537.1 - 1e-09 37.7 15.3 1.1e-05 24.9 0.2 3.0 3 0 0 3 3 3 2 PQ loop repeat TMEM51 PF15345.1 OAP54537.1 - 6.6e-05 22.7 0.0 9.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Protocadherin PF08374.6 OAP54537.1 - 0.16 11.5 0.1 0.66 9.5 0.0 2.0 3 0 0 3 3 3 0 Protocadherin DUF485 PF04341.7 OAP54537.1 - 5 6.9 7.6 1.8 8.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF485 SurE PF01975.12 OAP54539.1 - 2e-34 118.6 0.0 2.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Transp_cyt_pur PF02133.10 OAP54540.1 - 1.4e-95 320.4 35.9 1.6e-95 320.2 24.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Polysacc_deac_1 PF01522.16 OAP54541.1 - 4.8e-12 45.5 0.0 8.7e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase NARP1 PF12569.3 OAP54542.1 - 1.3e-195 651.1 19.7 2.3e-194 646.9 6.7 2.2 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 Fungal_trans PF04082.13 OAP54542.1 - 9.3e-26 90.2 0.4 2e-25 89.1 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_19 PF14559.1 OAP54542.1 - 1.9e-21 76.1 21.5 2.1e-05 24.7 2.3 6.4 5 1 1 6 6 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAP54542.1 - 3.8e-19 67.4 11.2 0.02 15.4 1.1 10.0 5 3 5 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAP54542.1 - 1.9e-18 66.5 22.9 0.00011 22.7 1.3 7.9 8 1 1 9 9 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAP54542.1 - 1.2e-15 56.9 29.2 1.1e-05 24.9 0.4 7.5 5 1 3 8 8 8 3 TPR repeat TPR_2 PF07719.12 OAP54542.1 - 2.1e-14 52.2 31.5 0.00061 19.5 0.0 10.7 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAP54542.1 - 6.8e-11 41.4 11.3 0.011 15.9 0.0 9.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAP54542.1 - 1.3e-09 37.8 21.4 0.0013 18.6 0.2 7.5 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAP54542.1 - 6.7e-08 31.8 27.4 2e-05 23.9 0.1 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAP54542.1 - 1.9e-07 30.8 11.7 0.0022 17.7 0.2 6.7 5 2 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 OAP54542.1 - 1.1e-06 28.6 20.6 0.0089 16.1 0.8 5.6 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 OAP54542.1 - 0.00026 21.2 22.5 2.4 8.7 0.2 9.2 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_3 PF07720.7 OAP54542.1 - 0.0032 17.2 1.8 1.1 9.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP54542.1 - 0.0087 15.7 26.6 0.019 14.7 0.0 7.4 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAP54542.1 - 0.018 14.8 16.9 2 8.4 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF2730 PF10805.3 OAP54542.1 - 0.022 14.4 0.1 46 3.8 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) Patatin PF01734.17 OAP54542.1 - 0.065 13.1 0.2 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 Patatin-like phospholipase Fis1_TPR_C PF14853.1 OAP54542.1 - 0.11 12.4 9.1 9.9 6.1 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 OAP54542.1 - 0.39 11.2 12.1 1 9.9 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Fungal_trans PF04082.13 OAP54543.1 - 2.3e-20 72.5 0.1 3.7e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54543.1 - 8.8e-09 35.1 9.2 1.4e-08 34.4 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 OAP54544.1 - 1.7e-75 254.3 26.2 1.9e-75 254.1 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP54544.1 - 2.5e-17 62.6 33.8 2.5e-17 62.6 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP54544.1 - 0.0018 16.7 32.8 0.0057 15.1 4.0 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein UPF0139 PF03669.8 OAP54544.1 - 0.46 10.0 2.9 0.28 10.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) FAD_binding_3 PF01494.14 OAP54545.1 - 4.8e-19 68.6 1.0 5.5e-18 65.1 0.7 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP54545.1 - 7e-07 29.5 0.8 2.2e-06 27.8 0.2 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP54545.1 - 2.6e-05 23.5 0.3 5.1e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP54545.1 - 3.1e-05 23.9 1.3 7.2e-05 22.7 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP54545.1 - 4e-05 22.7 2.0 0.00024 20.1 1.4 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 OAP54545.1 - 8.5e-05 21.6 9.0 0.014 14.2 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP54545.1 - 0.00012 22.4 2.4 0.029 14.7 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP54545.1 - 0.00029 19.6 3.0 0.13 10.9 0.0 2.8 2 1 1 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.19 OAP54545.1 - 0.00049 19.0 5.7 0.00091 18.1 3.9 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 OAP54545.1 - 0.0016 16.9 2.7 0.084 11.3 1.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAP54545.1 - 0.019 14.8 3.4 0.1 12.4 2.4 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP54545.1 - 0.028 13.3 4.1 0.051 12.4 2.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 OAP54545.1 - 0.11 11.5 0.4 0.21 10.6 0.3 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 OAP54545.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_3 PF01494.14 OAP54546.1 - 1.6e-23 83.3 1.4 1.8e-22 79.8 1.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP54546.1 - 3.6e-13 49.1 3.8 2.7e-06 26.5 2.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP54546.1 - 5.7e-08 33.0 0.7 7.1e-05 23.1 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP54546.1 - 1.1e-07 31.0 4.7 1.9e-07 30.3 3.3 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP54546.1 - 3e-06 26.3 2.3 7.7e-06 25.0 1.6 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAP54546.1 - 5.2e-06 26.4 4.2 4.1e-05 23.5 2.9 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP54546.1 - 5.4e-06 25.7 0.4 8.8e-06 25.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP54546.1 - 1.3e-05 25.1 2.4 1.3e-05 25.1 1.7 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP54546.1 - 2.2e-05 23.1 3.7 0.00062 18.3 1.9 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 OAP54546.1 - 0.00089 18.4 1.1 0.00089 18.4 0.7 1.9 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 OAP54546.1 - 0.00098 18.0 5.3 0.0029 16.5 3.7 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 OAP54546.1 - 0.0029 16.2 6.3 0.14 10.7 2.9 2.2 1 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 OAP54546.1 - 0.0051 16.9 1.0 0.017 15.1 0.7 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP54546.1 - 0.014 14.4 2.3 0.015 14.4 0.6 1.7 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 OAP54546.1 - 0.046 13.2 1.4 0.088 12.3 0.9 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 OAP54546.1 - 0.11 12.1 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HgmA PF04209.8 OAP54547.1 - 8.8e-122 406.5 0.0 1e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF4456 PF14644.1 OAP54548.1 - 0.0029 16.8 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) DUF1241 PF06840.6 OAP54548.1 - 0.068 12.4 0.8 2.9 7.1 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1241) DUF948 PF06103.6 OAP54548.1 - 0.13 12.1 0.3 3.6 7.5 0.0 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Beta-lactamase PF00144.19 OAP54551.1 - 5.1e-56 190.0 0.0 6.7e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 OAP54551.1 - 5.3e-09 35.8 0.1 9.6e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) TPR_12 PF13424.1 OAP54552.1 - 8.3e-15 54.4 6.4 8.6e-08 32.0 0.1 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 OAP54552.1 - 1.3e-14 53.7 0.0 9.7e-13 47.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TPR_11 PF13414.1 OAP54552.1 - 1.7e-06 27.5 3.3 0.00044 19.8 0.0 3.8 3 1 2 5 5 5 1 TPR repeat TPR_1 PF00515.23 OAP54552.1 - 1.9e-06 27.1 0.5 0.00053 19.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP54552.1 - 1.9e-05 24.2 6.7 0.017 14.9 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAP54552.1 - 0.00012 21.9 0.1 3.5 7.6 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.1 OAP54552.1 - 0.00014 21.8 1.0 0.0026 17.7 0.1 3.2 2 2 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.1 OAP54552.1 - 0.0012 18.4 0.0 2.5 8.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP54552.1 - 0.0023 17.5 0.9 0.051 13.3 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 OAP54552.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Apc3 PF12895.2 OAP54552.1 - 0.0087 16.1 0.8 0.09 12.9 0.2 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 OAP54552.1 - 0.011 16.0 0.7 4.6 7.6 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP54552.1 - 0.043 14.2 0.1 0.38 11.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP54552.1 - 0.091 13.4 9.5 5.1 8.0 0.0 6.2 6 2 2 8 8 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP54552.1 - 3.9 8.2 0.0 3.9 8.2 0.0 3.8 7 0 0 7 7 3 0 Tetratricopeptide repeat Aspzincin_M35 PF14521.1 OAP54555.1 - 0.011 16.2 0.0 0.028 14.9 0.0 1.6 1 1 0 1 1 1 0 Lysine-specific metallo-endopeptidase HNH_2 PF13391.1 OAP54559.1 - 0.0025 17.5 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.18 OAP54559.1 - 0.042 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease TPR_10 PF13374.1 OAP54561.1 - 7.2e-28 95.6 1.7 2.6e-10 39.8 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAP54561.1 - 4.7e-27 93.7 0.3 6.8e-12 45.1 0.2 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAP54561.1 - 2.2e-09 36.3 0.9 0.04 13.7 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAP54561.1 - 2.2e-08 33.5 0.1 0.00051 19.6 0.0 2.3 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 OAP54561.1 - 1.2e-06 28.9 0.2 0.0037 17.9 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 OAP54561.1 - 1.1e-05 25.4 0.2 0.036 14.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP54561.1 - 1.8e-05 24.2 0.1 0.97 9.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAP54561.1 - 6.1e-05 22.4 0.0 3.6 7.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.15 OAP54561.1 - 0.00026 20.7 0.0 2.6 8.2 0.0 3.2 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.1 OAP54561.1 - 0.0005 20.4 2.5 0.33 11.7 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAP54561.1 - 0.00065 19.7 0.0 0.61 10.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP54561.1 - 0.024 14.9 0.0 0.71 10.2 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat PPR_3 PF13812.1 OAP54561.1 - 0.026 14.7 0.2 15 6.1 0.1 3.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Apc3 PF12895.2 OAP54561.1 - 0.032 14.3 0.0 0.93 9.6 0.0 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 OAP54561.1 - 0.19 11.9 1.6 5.7 7.2 0.2 2.4 1 1 0 2 2 2 0 Bacterial transcriptional activator domain Matrilin_ccoil PF10393.4 OAP54562.1 - 0.00071 18.8 1.6 0.0036 16.6 0.1 2.1 1 1 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin DUF1110 PF06533.7 OAP54562.1 - 0.0073 16.1 1.2 0.0088 15.8 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1110) TMV_coat PF00721.16 OAP54562.1 - 0.0079 16.1 0.7 0.0086 16.0 0.5 1.1 1 0 0 1 1 1 1 Virus coat protein (TMV like) tRNA_NucTran2_2 PF13735.1 OAP54562.1 - 0.067 13.0 0.2 0.081 12.7 0.1 1.1 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative LUC7 PF03194.10 OAP54562.1 - 0.068 12.6 0.4 0.077 12.5 0.3 1.0 1 0 0 1 1 1 0 LUC7 N_terminus Ribonuc_red_lgC PF02867.10 OAP54565.1 - 2.2e-15 56.2 0.0 2.4e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain DUF2007 PF09413.5 OAP54567.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) DUF4470 PF14737.1 OAP54571.1 - 2.9e-25 87.9 0.0 6e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 OAP54571.1 - 5e-11 42.2 12.3 1e-10 41.3 8.5 1.6 1 0 0 1 1 1 1 MYND finger RRN7 PF11781.3 OAP54571.1 - 0.036 13.5 1.6 0.11 12.0 1.1 1.8 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 PAN_4 PF14295.1 OAP54572.1 - 0.3 10.8 9.5 0.11 12.2 3.7 2.2 2 0 0 2 2 2 0 PAN domain F-box PF00646.28 OAP54574.1 - 0.012 15.2 0.2 0.081 12.6 0.0 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 OAP54574.1 - 1.8 8.3 5.4 1.9 8.3 1.7 2.7 2 1 0 2 2 2 0 F-box-like DUF2732 PF10809.3 OAP54576.1 - 0.034 13.6 0.1 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) SpoIIIAH PF12685.2 OAP54577.1 - 6.2 6.2 11.1 31 3.9 7.7 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein SAF PF08666.7 OAP54578.1 - 6.3e-08 32.8 0.3 1.4e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 SAF domain GFO_IDH_MocA PF01408.17 OAP54578.1 - 1.4e-05 25.5 0.1 4.2e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 OAP54578.1 - 0.00013 22.2 0.0 0.00028 21.2 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Dabb PF07876.7 OAP54579.1 - 1.7e-16 60.4 0.0 2e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MFS_1 PF07690.11 OAP54580.1 - 1.5e-34 119.2 24.2 1.5e-34 119.2 16.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Aldedh PF00171.17 OAP54581.1 - 5e-174 578.9 0.1 5.6e-174 578.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ABM PF03992.11 OAP54582.1 - 1.5e-10 40.9 0.0 1.8e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cupin_2 PF07883.6 OAP54583.1 - 0.00015 21.2 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 OAP54583.1 - 0.092 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.7 OAP54583.1 - 0.11 11.8 0.0 0.71 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF861) FMN_dh PF01070.13 OAP54584.1 - 5.3e-124 413.6 0.0 7.3e-124 413.2 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAP54584.1 - 9.3e-25 86.2 0.0 2.4e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAP54584.1 - 2.4e-08 33.2 0.0 4.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 OAP54584.1 - 0.0002 20.6 0.1 0.00034 19.8 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAP54584.1 - 0.00022 20.2 0.3 0.00044 19.2 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 OAP54584.1 - 0.016 14.5 2.1 0.34 10.1 0.1 2.5 2 1 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.9 OAP54584.1 - 0.051 12.6 0.1 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Fungal_trans_2 PF11951.3 OAP54585.1 - 2.7e-14 52.5 0.0 1.9e-12 46.4 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Exo_endo_phos PF03372.18 OAP54587.1 - 1.4e-15 57.9 0.2 2.1e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAP54587.1 - 1.2e-14 53.9 0.0 4.7e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 OAP54587.1 - 0.00038 20.3 3.2 0.0011 18.8 2.2 1.8 1 0 0 1 1 1 1 GRF zinc finger DUF1162 PF06650.7 OAP54588.1 - 2.7e-89 299.0 0.0 1.7e-86 289.8 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 OAP54588.1 - 9.2e-44 147.7 0.2 3.6e-43 145.8 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 OAP54588.1 - 9.3e-05 22.5 2.9 0.00015 21.8 0.0 2.7 3 0 0 3 3 3 1 ATG C terminal domain GAS PF13851.1 OAP54589.1 - 0.0016 17.6 9.8 0.0032 16.6 6.8 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding RE_SacI PF09566.5 OAP54589.1 - 0.034 13.0 0.1 0.06 12.2 0.1 1.4 1 0 0 1 1 1 0 SacI restriction endonuclease ERM PF00769.14 OAP54589.1 - 0.072 12.6 17.6 0.009 15.5 9.2 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF972 PF06156.8 OAP54589.1 - 0.23 11.8 8.3 0.19 12.1 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Fzo_mitofusin PF04799.8 OAP54589.1 - 0.34 10.2 2.7 0.6 9.4 1.9 1.4 1 0 0 1 1 1 0 fzo-like conserved region AAA_23 PF13476.1 OAP54589.1 - 0.54 10.5 5.5 0.92 9.7 3.8 1.3 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 OAP54589.1 - 0.65 8.9 12.5 0.99 8.3 8.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CDC37_N PF03234.9 OAP54589.1 - 1 9.6 11.3 0.23 11.7 5.5 1.7 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding FUSC PF04632.7 OAP54589.1 - 1.3 7.3 11.3 2.4 6.4 7.8 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family GET2 PF08690.5 OAP54589.1 - 9.9 5.2 9.6 15 4.6 5.9 1.8 1 1 1 2 2 2 0 GET complex subunit GET2 AA_permease PF00324.16 OAP54590.1 - 1.9e-100 336.4 44.4 2.3e-100 336.2 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP54590.1 - 1.1e-26 93.3 49.1 1.3e-26 93.1 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease Baculo_PEP_C PF04513.7 OAP54591.1 - 0.00041 20.1 6.4 0.0011 18.7 4.5 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.4 OAP54591.1 - 0.00079 18.7 4.5 1.7 8.0 0.5 4.4 2 1 2 4 4 4 2 Trimeric coiled-coil oligomerisation domain of matrilin BLOC1_2 PF10046.4 OAP54591.1 - 0.0014 18.7 1.4 0.0034 17.4 0.9 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec34 PF04136.10 OAP54591.1 - 0.0022 17.7 3.2 0.0052 16.5 2.2 1.7 1 1 0 1 1 1 1 Sec34-like family TelA PF05816.6 OAP54591.1 - 0.0067 15.1 0.1 0.0089 14.7 0.1 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Allexi_40kDa PF05549.6 OAP54591.1 - 0.011 15.0 0.8 0.015 14.6 0.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein HSBP1 PF06825.7 OAP54591.1 - 0.015 14.8 4.6 0.23 11.0 2.1 2.8 1 1 1 2 2 2 0 Heat shock factor binding protein 1 DUF4463 PF14703.1 OAP54591.1 - 0.015 15.8 0.6 0.12 12.9 0.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) COG2 PF06148.6 OAP54591.1 - 0.015 15.1 0.3 0.027 14.3 0.2 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 OAP54591.1 - 0.017 13.8 1.6 0.023 13.3 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.4 OAP54591.1 - 0.023 14.5 0.6 0.048 13.5 0.2 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein NPV_P10 PF05531.7 OAP54591.1 - 0.025 14.8 6.1 0.15 12.2 2.5 2.7 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Streptin-Immun PF11083.3 OAP54591.1 - 0.026 14.5 0.4 0.07 13.1 0.2 1.8 1 1 0 1 1 1 0 Lantibiotic streptin immunity protein TBPIP PF07106.8 OAP54591.1 - 0.027 14.0 2.0 0.052 13.0 1.4 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fzo_mitofusin PF04799.8 OAP54591.1 - 0.028 13.8 1.3 0.043 13.2 0.9 1.4 1 1 0 1 1 1 0 fzo-like conserved region Snapin_Pallidin PF14712.1 OAP54591.1 - 0.029 14.6 2.1 0.071 13.4 1.4 1.7 1 1 0 1 1 1 0 Snapin/Pallidin Prominin PF05478.6 OAP54591.1 - 0.031 11.8 0.6 0.036 11.6 0.4 1.1 1 0 0 1 1 1 0 Prominin Tropomyosin PF00261.15 OAP54591.1 - 0.032 13.3 0.1 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Tropomyosin DUF16 PF01519.11 OAP54591.1 - 0.057 13.6 0.7 0.24 11.6 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 APG17 PF04108.7 OAP54591.1 - 0.062 12.1 1.5 0.085 11.6 1.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 MitMem_reg PF13012.1 OAP54591.1 - 0.068 13.2 2.0 0.13 12.3 1.4 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function KBP_C PF12309.3 OAP54591.1 - 0.084 11.8 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Flagellin_N PF00669.15 OAP54591.1 - 0.084 12.6 5.6 0.16 11.7 3.9 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region YPEB PF14620.1 OAP54591.1 - 0.093 11.7 1.0 0.12 11.3 0.7 1.1 1 0 0 1 1 1 0 YpeB sporulation Laminin_II PF06009.7 OAP54591.1 - 0.1 12.3 2.1 0.18 11.5 1.5 1.4 1 0 0 1 1 1 0 Laminin Domain II Adeno_PIX PF03955.9 OAP54591.1 - 0.12 12.9 0.4 0.27 11.7 0.2 1.7 1 1 0 1 1 1 0 Adenovirus hexon-associated protein (IX) RTX PF02382.10 OAP54591.1 - 0.13 10.5 0.6 0.15 10.3 0.4 1.1 1 0 0 1 1 1 0 RTX N-terminal domain Reo_sigmaC PF04582.7 OAP54591.1 - 0.14 11.3 4.1 0.2 10.7 2.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 OAP54591.1 - 0.21 11.4 3.3 1.4 8.7 2.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 OAP54591.1 - 0.25 11.5 1.9 1 9.5 1.3 1.9 1 1 1 2 2 2 0 Syntaxin TraF_2 PF13729.1 OAP54591.1 - 0.51 9.1 4.5 1.4 7.6 3.1 1.8 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF4319 PF14203.1 OAP54591.1 - 0.64 9.6 3.8 2.8 7.5 0.4 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4319) UPF0184 PF03670.8 OAP54591.1 - 7.7 6.7 9.7 14 5.9 0.2 2.8 2 1 1 3 3 2 0 Uncharacterised protein family (UPF0184) DUF1907 PF08925.6 OAP54592.1 - 1e-91 306.9 0.0 1.7e-91 306.2 0.0 1.3 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1907) PNP_UDP_1 PF01048.15 OAP54595.1 - 8.3e-10 38.0 1.0 2.2e-09 36.6 0.7 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily zf-rbx1 PF12678.2 OAP54595.1 - 1.5 9.0 4.0 26 5.0 0.1 2.9 3 0 0 3 3 3 0 RING-H2 zinc finger Ank_2 PF12796.2 OAP54596.1 - 4.3e-74 244.9 9.9 1.6e-17 63.6 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 OAP54596.1 - 3.1e-49 162.4 8.1 1.1e-08 34.4 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 OAP54596.1 - 7.8e-39 131.3 1.6 1.3e-05 25.6 0.0 8.4 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP54596.1 - 3.6e-27 91.7 0.1 0.00046 20.1 0.0 7.9 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 OAP54596.1 - 4.3e-24 83.9 7.5 3.8e-05 23.7 0.1 6.5 1 1 6 7 7 7 7 Ankyrin repeats (many copies) UBA PF00627.26 OAP54596.1 - 6.6e-06 25.7 0.0 82 3.2 0.0 7.1 7 0 0 7 7 7 0 UBA/TS-N domain HEM4 PF02602.10 OAP54596.1 - 0.025 13.8 1.0 28 3.8 0.0 4.1 1 1 2 4 4 4 0 Uroporphyrinogen-III synthase HemD Anoctamin PF04547.7 OAP54598.1 - 0.13 10.8 0.6 0.17 10.5 0.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Abhydrolase_3 PF07859.8 OAP54599.1 - 5.8e-23 81.5 0.0 9.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP54599.1 - 1.2e-05 25.2 0.1 2.7e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAP54599.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 OAP54599.1 - 0.099 11.5 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Ras PF00071.17 OAP54600.1 - 3.9e-12 45.8 0.0 8e-12 44.8 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 OAP54600.1 - 1.4e-10 41.6 0.0 2.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 OAP54600.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 OAP54600.1 - 0.021 14.4 0.3 0.044 13.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 OAP54600.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 OAP54600.1 - 0.029 14.5 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 OAP54600.1 - 0.044 12.9 0.1 0.057 12.5 0.1 1.3 1 1 0 1 1 1 0 KaiC MMR_HSR1 PF01926.18 OAP54600.1 - 0.048 13.6 0.0 0.2 11.6 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 OAP54600.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 OAP54600.1 - 0.067 11.9 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein ABC_tran PF00005.22 OAP54600.1 - 0.088 13.1 0.0 0.16 12.2 0.0 1.3 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 OAP54600.1 - 0.12 11.2 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 OAP54600.1 - 0.16 11.6 0.5 3.2 7.3 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase p450 PF00067.17 OAP54601.1 - 3.1e-45 154.5 0.0 4e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MEDS PF14417.1 OAP54601.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain ComX PF05952.7 OAP54601.1 - 0.063 12.7 0.2 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX RCR PF12273.3 OAP54602.1 - 1.3 9.6 7.2 2 9.0 3.6 2.2 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red FCH PF00611.18 OAP54603.1 - 7.5e-24 83.7 0.2 7.5e-24 83.7 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 OAP54603.1 - 1.7e-21 75.5 0.1 1.8e-10 40.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 OAP54603.1 - 9.1e-18 63.3 0.1 6.5e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 OAP54603.1 - 1.1e-13 50.6 6.1 1.8e-13 49.9 4.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 OAP54603.1 - 0.0036 16.7 0.0 0.025 14.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 OAP54603.1 - 0.0081 16.3 0.1 0.1 12.8 0.0 2.6 3 0 0 3 3 3 1 Bacterial SH3 domain Pyr_excise PF03013.9 OAP54603.1 - 0.14 11.9 5.7 0.29 10.9 1.1 2.5 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase C1_2 PF03107.11 OAP54603.1 - 0.64 10.1 7.2 1 9.5 5.0 1.3 1 0 0 1 1 1 0 C1 domain DEAD PF00270.24 OAP54604.1 - 1.9e-33 115.3 0.8 2.6e-32 111.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP54604.1 - 2.6e-21 75.2 0.2 5.6e-21 74.1 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 OAP54604.1 - 0.028 14.1 0.1 0.19 11.5 0.0 2.4 2 1 1 3 3 3 0 Part of AAA domain AAA_30 PF13604.1 OAP54604.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tachykinin PF02202.11 OAP54604.1 - 0.47 10.2 2.6 21 5.1 0.2 2.9 2 0 0 2 2 2 0 Tachykinin family GAF_2 PF13185.1 OAP54605.1 - 1.4e-11 45.0 0.4 2.8e-11 44.1 0.3 1.6 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 OAP54605.1 - 1.7e-06 28.2 0.0 2.3e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 OAP54605.1 - 0.00058 19.9 0.0 0.0008 19.5 0.0 1.3 1 1 0 1 1 1 1 GAF domain Metallophos PF00149.23 OAP54607.1 - 0.066 12.5 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase DLH PF01738.13 OAP54608.1 - 1.1e-11 44.4 4.5 9.9e-11 41.3 3.1 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP54608.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Tcp11 PF05794.8 OAP54609.1 - 3.9e-37 128.0 0.1 3.9e-37 128.0 0.0 1.6 2 0 0 2 2 2 1 T-complex protein 11 IQ PF00612.22 OAP54609.1 - 0.028 14.0 2.1 0.088 12.5 1.5 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Spc7 PF08317.6 OAP54609.1 - 0.13 10.9 6.5 0.24 10.0 4.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Nexin_C PF08628.7 OAP54609.1 - 0.69 10.0 0.0 0.69 10.0 0.0 3.5 4 1 1 5 5 5 0 Sorting nexin C terminal adh_short PF00106.20 OAP54610.1 - 4.8e-11 42.8 0.0 8.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP54610.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP54610.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 OAP54610.1 - 0.045 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Cytochrom_B561 PF03188.11 OAP54612.1 - 2.6e-05 24.0 8.9 0.00013 21.8 6.1 2.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Cation_efflux PF01545.16 OAP54612.1 - 0.45 9.5 4.9 0.83 8.6 3.4 1.5 1 0 0 1 1 1 0 Cation efflux family DUF4418 PF14387.1 OAP54612.1 - 2.1 8.1 4.4 0.49 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) DUF2427 PF10348.4 OAP54612.1 - 2.4 7.7 7.5 2 8.0 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) PQ-loop PF04193.9 OAP54613.1 - 3.2e-33 113.0 10.1 4.7e-18 64.5 0.7 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF1761 PF08570.5 OAP54613.1 - 0.00085 19.3 0.2 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) DUF3040 PF11239.3 OAP54613.1 - 0.031 14.3 3.4 0.5 10.4 0.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) DUF2254 PF10011.4 OAP54613.1 - 0.18 10.2 0.3 0.27 9.6 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) zf-C2H2 PF00096.21 OAP54614.1 - 0.0026 18.0 0.3 0.0026 18.0 0.2 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP54614.1 - 0.032 14.5 1.5 0.18 12.2 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP54614.1 - 0.61 10.4 3.6 0.34 11.2 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Zn_ribbon_recom PF13408.1 OAP54615.1 - 0.11 12.8 0.6 0.17 12.1 0.4 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Tim44 PF04280.10 OAP54616.1 - 0.034 14.1 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Tim44-like domain UPF0139 PF03669.8 OAP54617.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0139) SUI1 PF01253.17 OAP54618.1 - 7.7e-30 102.5 4.8 9.4e-30 102.2 3.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF520 PF04461.8 OAP54618.1 - 0.26 11.1 3.1 0.33 10.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF520) EOS1 PF12326.3 OAP54619.1 - 1.7e-14 53.6 1.2 3.9e-14 52.5 0.8 1.6 1 1 0 1 1 1 1 N-glycosylation protein TMEM237 PF15383.1 OAP54619.1 - 0.07 12.2 1.3 0.13 11.3 0.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 HCO3_cotransp PF00955.16 OAP54620.1 - 3.3e-67 227.3 15.6 1.7e-39 135.8 4.0 2.1 1 1 0 2 2 2 2 HCO3- transporter family Pkinase PF00069.20 OAP54621.1 - 6.6e-18 64.7 0.1 1.2e-17 63.9 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54621.1 - 2.1e-13 49.9 0.1 5e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP54621.1 - 0.12 11.3 0.0 0.26 10.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like GST_N_3 PF13417.1 OAP54622.1 - 1.8e-10 40.8 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP54622.1 - 8.2e-09 35.5 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP54622.1 - 1.9e-08 34.2 0.0 3.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP54622.1 - 2e-08 34.1 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP54622.1 - 3.6e-07 29.9 0.0 6.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP54622.1 - 6.1e-05 23.4 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 OAP54622.1 - 0.019 15.3 0.0 0.13 12.6 0.0 2.1 1 1 1 2 2 2 0 MetRS-N binding domain CTP_transf_2 PF01467.21 OAP54623.1 - 0.039 14.0 0.6 0.062 13.3 0.4 1.5 1 0 0 1 1 1 0 Cytidylyltransferase Astro_capsid PF03115.9 OAP54623.1 - 0.11 10.7 8.6 0.12 10.6 6.0 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BTV_NS2 PF04514.7 OAP54623.1 - 1.7 7.4 7.4 2.5 6.8 5.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF605 PF04652.11 OAP54623.1 - 5.1 6.3 20.5 0.11 11.9 9.5 1.5 2 0 0 2 2 2 0 Vta1 like SDA1 PF05285.7 OAP54623.1 - 7.7 5.7 17.6 12 5.0 12.2 1.4 1 0 0 1 1 1 0 SDA1 DUF2076 PF09849.4 OAP54624.1 - 3.6e-08 33.7 10.8 4.6e-08 33.4 7.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 OAP54624.1 - 2.5e-05 24.0 3.8 3.7e-05 23.5 2.7 1.3 1 0 0 1 1 1 1 CHCH domain zf-CCHC PF00098.18 OAP54625.1 - 2.6e-11 42.8 9.2 1.8e-05 24.4 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 OAP54625.1 - 7.5e-09 35.1 0.1 1.4e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 OAP54625.1 - 5.4e-06 25.9 0.2 1.2e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 OAP54625.1 - 4.1e-05 23.2 4.1 0.039 13.6 1.2 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 OAP54625.1 - 0.0011 18.5 5.7 0.32 10.6 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 OAP54625.1 - 0.03 13.9 9.8 0.4 10.3 0.4 2.8 3 0 0 3 3 3 0 Zinc knuckle adh_short PF00106.20 OAP54627.1 - 2.7e-14 53.4 0.1 4.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP54627.1 - 6.2e-08 32.5 0.1 8.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP54627.1 - 0.055 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ribosomal_L7Ae PF01248.21 OAP54628.1 - 1.6e-19 69.1 0.1 4.5e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3693 PF12472.3 OAP54628.1 - 1 9.0 7.2 2.1 8.0 4.3 2.1 1 1 1 2 2 2 0 Phage related protein Daxx PF03344.10 OAP54628.1 - 1.4 7.2 25.2 0.085 11.3 12.5 1.9 2 0 0 2 2 2 0 Daxx Family CorA PF01544.13 OAP54629.1 - 4.6e-09 35.7 1.2 1.1e-08 34.5 0.7 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SNARE_assoc PF09335.6 OAP54630.1 - 2.7e-13 50.2 5.1 2.7e-13 50.2 3.6 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF1049 PF06305.6 OAP54630.1 - 0.47 9.9 0.0 0.47 9.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) PgaD PF13994.1 OAP54630.1 - 4.7 6.6 7.7 11 5.4 1.1 2.5 3 0 0 3 3 3 0 PgaD-like protein DUF1771 PF08590.5 OAP54631.1 - 8.6e-15 54.5 13.0 1.5e-14 53.6 9.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 OAP54631.1 - 4.7e-12 45.9 0.7 3.1e-11 43.2 0.0 2.6 3 0 0 3 3 3 1 Smr domain zf-CCCH PF00642.19 OAP54631.1 - 2.8e-10 39.6 2.8 0.00023 20.7 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TIM21 PF08294.6 OAP54632.1 - 8.5e-29 100.0 0.0 1.2e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 OAP54632.1 - 0.0025 17.3 0.0 0.0082 15.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RhoGAP PF00620.22 OAP54633.1 - 2.6e-37 127.7 0.0 4.1e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Hydrolase_6 PF13344.1 OAP54634.1 - 4.6e-23 81.0 0.0 1e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP54634.1 - 1.3e-10 40.7 0.0 9e-10 38.1 0.0 2.5 1 1 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 OAP54634.1 - 0.0036 17.5 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP54634.1 - 0.038 14.4 0.0 1.9 8.8 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Lipase_3 PF01764.20 OAP54634.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.9 OAP54635.1 - 3.7e-50 170.2 0.0 5.1e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 OAP54635.1 - 6.3e-09 36.0 0.1 1.8e-08 34.5 0.0 1.7 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP54635.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP54635.1 - 0.0004 20.0 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 OAP54635.1 - 0.00084 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 OAP54635.1 - 0.017 14.2 0.0 0.068 12.2 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.11 OAP54635.1 - 0.061 12.7 0.0 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.7 OAP54635.1 - 0.092 12.4 0.2 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PE-PPE PF08237.6 OAP54635.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Arf PF00025.16 OAP54637.1 - 6.2e-74 246.9 0.1 7.3e-74 246.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 OAP54637.1 - 1.4e-11 44.0 0.0 1.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 OAP54637.1 - 2.6e-11 43.1 0.0 3.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 OAP54637.1 - 5.7e-11 41.7 1.8 1.9e-07 30.1 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 OAP54637.1 - 1.2e-10 40.8 0.0 1.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 OAP54637.1 - 1.9e-06 28.3 0.0 2.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAP54637.1 - 0.00019 21.3 0.1 0.00035 20.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 OAP54637.1 - 0.021 13.9 0.1 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Epimerase PF01370.16 OAP54638.1 - 3.5e-18 65.8 0.0 4.9e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 OAP54638.1 - 1.9e-11 43.4 0.0 6e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 OAP54638.1 - 5.9e-07 29.5 0.0 9.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAP54638.1 - 2.9e-05 24.1 0.0 0.00012 22.1 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP54638.1 - 0.00031 19.7 0.0 0.00058 18.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 OAP54638.1 - 0.00061 18.5 0.0 0.0048 15.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAP54638.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 OAP54638.1 - 0.16 10.8 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Vezatin PF12632.2 OAP54640.1 - 5.4e-34 117.4 0.1 9.7e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes UPF0697 PF15117.1 OAP54640.1 - 0.0016 18.1 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0697 DctQ PF04290.7 OAP54640.1 - 0.028 14.1 0.3 0.049 13.4 0.2 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component HR1 PF02185.11 OAP54640.1 - 4.4 7.1 7.4 0.22 11.3 0.2 2.3 3 0 0 3 3 3 0 Hr1 repeat PCNA_N PF00705.13 OAP54641.1 - 1.4e-52 176.5 4.9 2.3e-52 175.7 3.4 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 OAP54641.1 - 3.3e-52 175.7 0.3 1.1e-51 174.0 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 OAP54641.1 - 1.8e-09 36.7 1.6 2.3e-05 23.3 0.2 2.2 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 OAP54641.1 - 4.3e-09 35.8 0.4 5.9e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 Rad9 Nro1 PF12753.2 OAP54641.1 - 3.3e-05 23.0 0.1 5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 Hus1 PF04005.7 OAP54641.1 - 0.00037 19.5 0.8 0.0017 17.3 0.1 2.1 2 1 0 2 2 2 1 Hus1-like protein Phos_pyr_kin PF08543.7 OAP54642.1 - 1.6e-12 47.2 0.0 3e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 OAP54642.1 - 4.6e-08 32.5 0.3 2.3e-07 30.2 0.1 2.1 2 1 0 2 2 2 1 pfkB family carbohydrate kinase dUTPase PF00692.14 OAP54643.1 - 3.4e-44 149.4 0.0 4.3e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase APH PF01636.18 OAP54644.1 - 1.8e-41 142.4 0.0 3.4e-41 141.5 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAP54644.1 - 1.3e-05 24.5 0.1 2.4e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 OAP54644.1 - 0.00035 19.3 0.0 0.0029 16.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Kdo PF06293.9 OAP54644.1 - 0.0017 17.4 0.0 0.0068 15.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.9 OAP54644.1 - 0.0028 16.7 0.0 0.42 9.5 0.0 2.3 2 0 0 2 2 2 2 Fructosamine kinase Choline_kinase PF01633.15 OAP54644.1 - 0.0029 17.2 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 OAP54644.1 - 0.0045 16.3 0.0 0.071 12.4 0.0 2.1 2 0 0 2 2 2 1 RIO1 family zf-C2H2_4 PF13894.1 OAP54645.1 - 2.9e-07 30.3 6.9 0.24 11.8 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP54645.1 - 0.00032 20.8 8.2 0.0062 16.8 0.1 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type Med27 PF11571.3 OAP54646.1 - 4.5e-11 42.7 0.0 9.2e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 Thioredoxin_5 PF13743.1 OAP54646.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Menin PF05053.8 OAP54648.1 - 1.4 6.9 5.2 2.1 6.4 3.6 1.2 1 0 0 1 1 1 0 Menin Sporozoite_P67 PF05642.6 OAP54648.1 - 2.8 5.6 9.5 3.8 5.2 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pex14_N PF04695.8 OAP54649.1 - 0.08 12.9 5.9 0.091 12.8 4.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1075 PF06388.6 OAP54649.1 - 0.67 9.5 3.6 1 9.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) SR-25 PF10500.4 OAP54649.1 - 1 8.8 8.0 1.1 8.6 5.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dicty_REP PF05086.7 OAP54649.1 - 1.7 6.3 5.3 1.8 6.2 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3984 PF13136.1 OAP54649.1 - 3.3 6.8 19.6 3.7 6.6 13.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF566 PF04484.7 OAP54649.1 - 3.7 6.9 9.0 3.6 7.0 6.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) TPR_11 PF13414.1 OAP54650.1 - 3.3e-16 58.6 6.1 8.8e-09 34.8 0.0 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAP54650.1 - 3.9e-13 48.4 8.3 2.3e-06 26.9 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAP54650.1 - 9e-13 47.0 4.5 0.00016 21.3 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAP54650.1 - 3.1e-10 39.8 0.1 4.5e-05 23.2 0.0 3.0 2 1 2 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 OAP54650.1 - 3.4e-09 36.2 0.3 6.6e-09 35.3 0.2 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.1 OAP54650.1 - 8.7e-07 28.2 0.3 6.6e-05 22.4 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP54650.1 - 1.2e-06 27.8 0.5 0.02 14.6 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAP54650.1 - 3.5e-05 23.9 0.3 9.3 6.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP54650.1 - 6.7e-05 23.4 0.7 0.0079 16.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAP54650.1 - 0.00016 21.6 0.1 0.0086 16.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAP54650.1 - 0.0012 18.7 0.8 2.6 7.9 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP54650.1 - 0.0047 17.4 0.4 0.44 11.3 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat Sod_Cu PF00080.15 OAP54651.1 - 5.3e-14 52.5 0.0 8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 OAP54651.1 - 2.7e-11 43.4 0.0 5.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain SET PF00856.23 OAP54652.1 - 5e-13 49.6 0.0 1e-12 48.6 0.0 1.5 2 0 0 2 2 2 1 SET domain Pkinase PF00069.20 OAP54653.1 - 1.9e-06 27.2 0.1 3.8e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain DUF3275 PF11679.3 OAP54653.1 - 1.5 8.3 6.0 2.5 7.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Pkinase PF00069.20 OAP54654.1 - 6.9e-48 163.0 0.0 8e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54654.1 - 7e-19 67.9 0.0 9e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAP54654.1 - 0.00035 19.6 0.0 0.00052 19.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAP54654.1 - 0.0029 16.6 0.0 0.0053 15.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 OAP54654.1 - 0.0098 15.6 0.8 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family tRNA-synt_1 PF00133.17 OAP54655.1 - 3.3e-39 134.3 0.0 3.9e-30 104.4 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAP54655.1 - 1.3e-19 70.1 0.2 1.4e-11 43.6 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 OAP54655.1 - 1.2e-09 38.1 0.3 2.9e-09 36.8 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 OAP54655.1 - 2.7e-07 30.0 0.0 4.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Acetyltransf_8 PF13523.1 OAP54656.1 - 3.1e-48 163.5 0.0 4.5e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAP54656.1 - 0.0026 17.9 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain OCD_Mu_crystall PF02423.10 OAP54657.1 - 3.8e-17 62.0 0.4 2.2e-07 29.9 0.0 3.6 4 1 0 4 4 4 3 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 OAP54657.1 - 3.6e-05 23.8 0.0 0.00058 19.9 0.0 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 OAP54658.1 - 2.4e-24 85.7 32.4 2.4e-24 85.7 22.4 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF791 PF05631.9 OAP54658.1 - 0.0008 18.2 0.1 0.0017 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Syndecan PF01034.15 OAP54658.1 - 0.53 9.9 4.3 1.8 8.2 0.2 2.9 2 0 0 2 2 2 0 Syndecan domain Clat_adaptor_s PF01217.15 OAP54660.1 - 3.8e-44 149.8 0.0 6.6e-44 149.0 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.18 OAP54661.1 - 1.1e-17 63.9 0.0 2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAP54661.1 - 8.2e-06 25.3 0.0 5.1e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 OAP54661.1 - 0.00011 21.4 0.2 0.00027 20.2 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 OAP54661.1 - 0.00012 21.3 0.1 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 OAP54661.1 - 0.00017 21.4 0.1 0.013 15.2 0.1 2.6 2 0 0 2 2 2 1 Dynamin family Septin PF00735.13 OAP54661.1 - 0.00072 18.6 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Septin SRPRB PF09439.5 OAP54661.1 - 0.0028 16.8 0.0 0.0058 15.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 OAP54661.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 OAP54661.1 - 0.036 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B WD40 PF00400.27 OAP54662.1 - 1.1e-59 196.3 12.1 1.3e-09 37.5 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box PF00646.28 OAP54662.1 - 2.3e-12 46.2 0.1 5.2e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP54662.1 - 4.9e-12 45.3 0.2 1.2e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.1 OAP54662.1 - 6.5e-05 22.6 0.2 6.6 6.5 0.0 4.8 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 OAP54662.1 - 0.00051 18.3 7.9 1.5 6.8 0.1 5.0 2 2 4 6 6 6 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 OAP54662.1 - 0.012 15.0 0.9 0.16 11.4 0.0 2.7 2 1 1 3 3 3 0 PQQ-like domain PRANC PF09372.5 OAP54662.1 - 0.21 11.5 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain HORMA PF02301.13 OAP54663.1 - 5.5e-29 101.1 0.0 9e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 OAP54663.1 - 0.00054 19.5 13.5 0.0015 18.1 9.3 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAP54663.1 - 6.5 6.1 11.2 2.6 7.4 5.6 2.0 2 0 0 2 2 2 0 PHD-finger DUF1510 PF07423.6 OAP54664.1 - 1.5 8.0 4.1 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nuc_sug_transp PF04142.10 OAP54665.1 - 1.1e-76 257.1 4.5 1.7e-76 256.5 3.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 OAP54665.1 - 7.3e-08 31.6 12.1 0.00023 20.2 2.4 2.2 2 0 0 2 2 2 2 UAA transporter family EmrE PF13536.1 OAP54665.1 - 2.5e-06 27.6 3.8 2.5e-06 27.6 2.7 2.9 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 OAP54665.1 - 2.6e-05 24.2 9.3 2.6e-05 24.2 6.5 3.7 2 2 1 3 3 3 1 EamA-like transporter family TPT PF03151.11 OAP54665.1 - 0.00036 20.2 5.6 0.00036 20.2 3.9 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family Sec63 PF02889.11 OAP54666.1 - 7.9e-50 169.8 0.0 1.2e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 OAP54666.1 - 3.4e-27 95.0 0.1 9.6e-27 93.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP54666.1 - 3.5e-09 36.3 0.0 7.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP54666.1 - 5.7e-09 36.0 0.2 3.3e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 OAP54666.1 - 0.00058 19.5 0.0 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 OAP54666.1 - 0.0016 18.6 0.1 0.0045 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 OAP54666.1 - 0.013 14.4 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 OAP54666.1 - 0.016 14.5 2.0 0.024 13.9 0.0 2.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 OAP54666.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.1 OAP54666.1 - 0.089 12.9 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain ADH_N PF08240.7 OAP54667.1 - 6.1e-22 77.4 0.7 1.2e-21 76.4 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP54667.1 - 3.2e-16 59.0 0.0 5.2e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAP54667.1 - 6.9e-05 22.0 0.1 0.00011 21.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 OAP54667.1 - 0.00086 20.2 0.0 0.0015 19.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 OAP54667.1 - 0.01 15.6 0.1 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 OAP54667.1 - 0.014 15.0 0.1 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 OAP54667.1 - 0.026 14.1 0.2 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 OAP54667.1 - 0.036 14.1 0.0 0.091 12.8 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PGAP1 PF07819.8 OAP54668.1 - 2.6e-82 275.7 0.0 4.3e-82 275.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 OAP54668.1 - 2.2e-07 30.7 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP54668.1 - 4.1e-06 26.8 0.2 8.8e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP54668.1 - 7.2e-05 22.4 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 OAP54668.1 - 0.002 17.4 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 OAP54668.1 - 0.014 14.3 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF4050 PF13259.1 OAP54670.1 - 1e-36 125.5 0.2 2e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) HhH-GPD PF00730.20 OAP54672.1 - 2.8e-09 37.2 0.0 7.6e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Sel1 PF08238.7 OAP54673.1 - 1.9e-14 53.7 5.8 0.00049 20.6 0.2 4.5 4 0 0 4 4 4 3 Sel1 repeat FR47 PF08445.5 OAP54673.1 - 3.5e-06 26.6 0.1 0.0065 16.1 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.1 OAP54673.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP54673.1 - 0.035 14.1 1.1 0.96 9.5 0.1 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Pkinase PF00069.20 OAP54674.1 - 2.4e-29 102.2 0.0 3e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54674.1 - 6.2e-11 41.8 0.0 9.3e-11 41.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP54674.1 - 9.1e-08 32.1 0.2 0.0068 16.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.11 OAP54674.1 - 0.089 12.7 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 ABC1 family Kinase-like PF14531.1 OAP54674.1 - 0.091 11.7 0.0 0.33 9.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like AA_permease PF00324.16 OAP54676.1 - 1.4e-104 350.1 45.3 1.6e-104 349.8 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP54676.1 - 1.5e-29 102.7 51.0 2e-29 102.3 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease DAO PF01266.19 OAP54677.1 - 1.9e-46 158.6 0.0 3.4e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP54677.1 - 3.5e-06 26.9 0.0 1.6e-05 24.8 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.13 OAP54677.1 - 4.8e-06 25.6 0.8 1e-05 24.5 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trp_halogenase PF04820.9 OAP54677.1 - 5.2e-05 22.0 0.1 0.00013 20.7 0.0 1.6 1 1 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 OAP54677.1 - 0.00015 21.6 0.0 0.00078 19.3 0.0 2.2 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP54677.1 - 0.0017 17.4 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 OAP54677.1 - 0.0081 15.0 1.8 0.022 13.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain ThiF PF00899.16 OAP54677.1 - 0.015 15.0 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 ThiF family KR PF08659.5 OAP54677.1 - 0.018 14.6 0.0 0.049 13.2 0.0 1.7 1 0 0 1 1 1 0 KR domain Pyr_redox_3 PF13738.1 OAP54677.1 - 0.027 14.5 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAP54677.1 - 0.047 13.6 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 OAP54677.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 OAP54677.1 - 0.081 12.2 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ASFV_J13L PF05568.6 OAP54677.1 - 0.11 12.0 1.3 0.2 11.1 0.9 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Thi4 PF01946.12 OAP54677.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 OAP54677.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 OAP54677.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 OAP54677.1 - 0.14 11.0 0.2 0.65 8.9 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase GIDA PF01134.17 OAP54677.1 - 0.34 9.7 0.0 1.3 7.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.19 OAP54678.1 - 1.7e-51 175.2 0.0 1.9e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP54678.1 - 4.6e-06 26.5 0.0 1.1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP54678.1 - 0.00017 21.6 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP54678.1 - 0.0017 18.4 0.0 0.026 14.6 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 OAP54678.1 - 0.0019 17.9 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP54678.1 - 0.0045 16.8 0.1 0.64 9.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP54678.1 - 0.013 14.4 2.2 1.3 7.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 OAP54678.1 - 0.014 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 OAP54678.1 - 0.078 11.8 0.1 4.6 5.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 OAP54678.1 - 0.1 11.2 0.7 5.3 5.5 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Transglut_core PF01841.14 OAP54678.1 - 0.11 12.6 0.8 0.39 10.9 0.5 1.9 1 1 0 1 1 1 0 Transglutaminase-like superfamily Sulfate_transp PF00916.15 OAP54679.1 - 3e-72 242.9 9.0 5.9e-72 242.0 6.2 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 OAP54679.1 - 5.8e-32 109.2 2.5 5.8e-32 109.2 1.7 3.6 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 OAP54679.1 - 3.2e-09 36.2 0.0 6.9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 OAP54679.1 - 0.011 15.4 0.7 0.011 15.4 0.5 2.5 2 0 0 2 2 2 0 Stannin transmembrane DnaJ PF00226.26 OAP54680.1 - 1.6e-25 88.5 2.4 2.8e-25 87.8 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAP54680.1 - 1e-22 79.8 0.4 8.7e-20 70.4 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 OAP54680.1 - 7.2e-14 51.5 18.3 1.3e-13 50.7 12.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 OAP54680.1 - 0.22 11.1 10.6 0.41 10.3 1.5 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 OAP54680.1 - 0.37 10.6 6.5 4.9 7.0 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 OAP54680.1 - 1.4 8.7 5.5 3.8 7.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zf-RING_3 PF14369.1 OAP54680.1 - 5 7.1 7.0 12 5.9 0.0 3.2 4 0 0 4 4 4 0 zinc-finger Clr5 PF14420.1 OAP54681.1 - 4.4e-18 64.9 0.8 7.4e-18 64.1 0.5 1.4 1 0 0 1 1 1 1 Clr5 domain p450 PF00067.17 OAP54682.1 - 1e-39 136.3 0.0 2.8e-39 134.9 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Telomere_Sde2 PF13019.1 OAP54683.1 - 1e-55 187.8 0.8 1.4e-55 187.4 0.5 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DOCK-C2 PF14429.1 OAP54684.1 - 2.2e-28 99.1 0.0 4.2e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.1 OAP54684.1 - 2.5e-06 26.9 0.0 7.1e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAP54684.1 - 1.2e-05 24.5 0.0 2.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain NOSIC PF08060.8 OAP54684.1 - 0.058 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 NOSIC (NUC001) domain SH3_2 PF07653.12 OAP54684.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Suc_Fer-like PF06999.7 OAP54685.1 - 3.5e-33 115.5 0.0 7.9e-30 104.5 0.0 2.2 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Suf PF05843.9 OAP54685.1 - 0.074 12.7 2.5 0.1 12.3 1.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Dicty_REP PF05086.7 OAP54685.1 - 2.4 5.7 5.5 3.2 5.3 3.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SART-1 PF03343.8 OAP54686.1 - 3.3e-135 451.8 68.1 4e-135 451.5 47.2 1.0 1 0 0 1 1 1 1 SART-1 family Aminotran_1_2 PF00155.16 OAP54687.1 - 4.6e-92 308.7 0.0 5.5e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Hpt PF01627.18 OAP54688.1 - 3.8e-11 42.8 0.1 5.8e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Hpt domain zf-H2C2_2 PF13465.1 OAP54689.1 - 6.7e-22 76.6 20.3 6.6e-07 29.3 0.1 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 OAP54689.1 - 4.7e-17 61.2 33.8 5.2e-05 23.3 0.8 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP54689.1 - 9.4e-10 38.1 35.0 0.00055 20.0 1.7 4.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAP54689.1 - 2.1e-05 24.4 5.4 2.4 8.4 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAP54689.1 - 0.00043 20.0 11.1 0.63 10.0 0.3 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 OAP54689.1 - 0.0017 18.4 10.3 0.49 10.6 0.1 4.8 4 1 1 5 5 5 2 Zinc-finger of C2H2 type C1_4 PF07975.7 OAP54689.1 - 0.59 10.1 6.6 2.6 8.1 0.7 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain XPA_N PF01286.13 OAP54689.1 - 1.4 8.7 3.6 0.84 9.3 0.1 2.3 3 0 0 3 3 3 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 OAP54689.1 - 2.3 8.2 8.8 13 5.7 0.0 3.9 2 1 2 4 4 4 0 Zinc ribbon domain Sec3_C PF09763.4 OAP54690.1 - 8.5e-188 625.7 20.0 1.1e-187 625.3 13.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 OAP54690.1 - 3e-27 94.2 0.0 8.2e-27 92.9 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Mg_trans_NIPA PF05653.9 OAP54691.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA RhoGAP PF00620.22 OAP54692.1 - 5.1e-48 162.5 0.5 1.4e-47 161.0 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 OAP54692.1 - 2.4e-14 53.1 17.8 1.8e-09 37.5 1.3 2.4 2 0 0 2 2 2 2 LIM domain zinc_ribbon_2 PF13240.1 OAP54692.1 - 0.36 10.3 9.5 0.88 9.1 0.0 4.5 4 1 0 4 4 4 0 zinc-ribbon domain LMSTEN PF07988.7 OAP54692.1 - 0.5 9.7 4.1 0.43 9.9 0.9 2.4 2 0 0 2 2 2 0 LMSTEN motif FUSC PF04632.7 OAP54692.1 - 0.87 7.9 0.1 1.7 6.9 0.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Zn-ribbon_8 PF09723.5 OAP54692.1 - 1.5 8.8 18.6 0.71 9.8 0.9 4.2 3 1 1 4 4 4 0 Zinc ribbon domain CLASP_N PF12348.3 OAP54693.1 - 5.8e-43 146.8 0.0 1.1e-42 145.9 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal Cornifin PF02389.10 OAP54693.1 - 0.0059 16.4 6.2 0.0059 16.4 4.3 1.9 2 0 0 2 2 2 1 Cornifin (SPRR) family P_C PF06640.6 OAP54693.1 - 0.033 14.1 2.1 0.071 13.0 1.5 1.5 1 0 0 1 1 1 0 P protein C-terminus Excalibur PF05901.6 OAP54693.1 - 0.048 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Excalibur calcium-binding domain HEAT_EZ PF13513.1 OAP54693.1 - 0.086 13.3 0.1 2.1 8.9 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat BSP PF04450.7 OAP54694.1 - 1.3e-63 214.2 0.0 1.5e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 OAP54694.1 - 2.8e-07 30.6 0.0 3.4e-05 23.8 0.0 2.4 1 1 0 1 1 1 1 Peptidase MA superfamily Ribosomal_L10 PF00466.15 OAP54695.1 - 3e-17 62.3 0.0 6.4e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 OAP54695.1 - 1.1e-16 60.9 9.0 3.2e-16 59.4 5.0 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.27 OAP54696.1 - 0.00023 20.9 0.1 0.16 11.9 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.10 OAP54696.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.6 1 0 0 1 1 1 0 CPSF A subunit region URO-D PF01208.12 OAP54697.1 - 5.4e-106 354.3 0.0 6.5e-106 354.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.17 OAP54698.1 - 1.6e-12 46.9 0.1 2.3e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 OAP54698.1 - 0.014 15.2 0.9 0.02 14.7 0.6 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase DUF3725 PF12523.3 OAP54698.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Eclosion PF04736.7 OAP54698.1 - 0.15 11.5 0.6 6.5 6.2 0.0 2.2 1 1 1 2 2 2 0 Eclosion hormone adh_short PF00106.20 OAP54699.1 - 3.4e-15 56.3 1.0 6.6e-10 39.1 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAP54699.1 - 3.3e-06 26.8 0.1 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAP54699.1 - 0.00074 19.3 0.4 0.059 13.1 0.0 2.2 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SH3_9 PF14604.1 OAP54700.1 - 6.2e-11 41.7 0.0 1.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAP54700.1 - 3e-08 32.9 0.0 4.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAP54700.1 - 1e-07 31.3 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain VSP PF03302.8 OAP54700.1 - 8e-06 24.7 0.8 1.3e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Pkinase PF00069.20 OAP54701.1 - 9.3e-45 152.7 0.0 1.4e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54701.1 - 1.8e-20 73.0 0.0 2.6e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP54701.1 - 7.1e-06 25.9 0.1 0.0049 16.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 OAP54701.1 - 0.0017 17.4 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 OAP54701.1 - 0.045 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 OAP54701.1 - 0.047 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAP54701.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TAFH PF07531.9 OAP54701.1 - 0.084 12.5 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 NHR1 homology to TAF Choline_kinase PF01633.15 OAP54701.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase muHD PF10291.4 OAP54702.1 - 8.2e-66 221.8 0.0 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 OAP54702.1 - 1.4e-11 44.3 0.0 4e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.16 OAP54702.1 - 0.00015 20.9 0.0 0.0012 17.9 0.0 2.0 1 1 0 1 1 1 1 Adaptor complexes medium subunit family NUFIP1 PF10453.4 OAP54702.1 - 0.091 12.2 0.1 0.24 10.9 0.1 1.7 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) TPR_MLP1_2 PF07926.7 OAP54702.1 - 3.1 7.5 7.8 0.21 11.3 0.9 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TFIIF_alpha PF05793.7 OAP54703.1 - 0.011 14.1 57.8 0.18 10.1 40.1 2.9 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.14 OAP54704.1 - 7.8e-18 64.1 0.0 1.8e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase adh_short PF00106.20 OAP54705.1 - 1.1e-20 74.2 1.6 4.6e-20 72.1 1.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP54705.1 - 5.7e-08 32.6 1.0 2.9e-05 23.7 0.2 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 OAP54705.1 - 5.4e-05 23.0 0.1 0.00016 21.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 OAP54705.1 - 0.0019 17.3 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.14 OAP54705.1 - 0.0032 16.2 0.1 0.0046 15.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP54705.1 - 0.12 11.8 0.3 0.54 9.6 0.0 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1168 PF06658.7 OAP54706.1 - 4.2e-40 136.5 18.7 5.5e-40 136.1 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF1675 PF07897.6 OAP54706.1 - 0.14 12.0 9.6 0.18 11.6 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Dsh_C PF12316.3 OAP54706.1 - 0.64 10.1 5.6 0.81 9.7 3.9 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TEX19 PF15553.1 OAP54706.1 - 1.4 8.7 3.5 2.3 8.0 2.4 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 Ycf1 PF05758.7 OAP54706.1 - 3.3 5.3 7.0 3.5 5.2 4.8 1.0 1 0 0 1 1 1 0 Ycf1 Mur_ligase_M PF08245.7 OAP54707.1 - 9.2e-06 25.8 0.4 5.6e-05 23.2 0.3 2.1 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 OAP54707.1 - 0.00021 21.2 0.0 0.00049 20.0 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain TP_methylase PF00590.15 OAP54707.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases ECH PF00378.15 OAP54708.1 - 3e-33 114.9 0.0 3.8e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TPR_12 PF13424.1 OAP54709.1 - 2.4e-110 360.6 52.1 1e-19 70.2 1.8 7.4 3 1 6 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 OAP54709.1 - 5.3e-77 251.8 31.2 1.1e-10 41.0 0.3 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.23 OAP54709.1 - 9.7e-41 135.7 48.1 7.6e-05 22.1 0.4 9.9 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 OAP54709.1 - 1.1e-35 118.6 37.3 0.00055 19.6 0.1 10.1 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 OAP54709.1 - 4e-35 116.8 22.7 0.0017 18.0 0.2 9.6 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 OAP54709.1 - 6e-35 118.7 31.1 1.7e-09 37.1 0.5 7.1 2 2 5 7 7 7 7 TPR repeat TPR_14 PF13428.1 OAP54709.1 - 3.3e-27 92.4 28.9 0.032 14.8 0.0 11.0 7 1 4 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 OAP54709.1 - 9.7e-23 78.2 31.7 0.044 13.5 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat HET PF06985.6 OAP54709.1 - 1.6e-20 73.7 10.4 1.3e-19 70.7 4.4 3.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_17 PF13431.1 OAP54709.1 - 2.8e-19 67.6 15.6 0.61 10.4 0.0 10.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 OAP54709.1 - 4.1e-18 65.5 33.6 7.7e-05 23.2 0.8 7.5 6 2 2 8 8 7 6 Tetratricopeptide repeat RPN7 PF10602.4 OAP54709.1 - 1.9e-13 50.1 17.0 0.28 10.5 0.0 9.0 4 3 4 9 9 9 5 26S proteasome subunit RPN7 Ribosomal_S7 PF00177.16 OAP54709.1 - 5.5e-12 45.5 0.0 2.6 7.6 0.0 7.3 2 1 6 8 8 7 4 Ribosomal protein S7p/S5e TPR_4 PF07721.9 OAP54709.1 - 1.7e-11 43.3 0.0 17 6.2 0.0 8.8 8 0 0 8 8 8 0 Tetratricopeptide repeat NB-ARC PF00931.17 OAP54709.1 - 5.7e-11 41.8 0.0 8.8e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF2225 PF09986.4 OAP54709.1 - 1.2e-07 31.4 7.1 0.00069 19.1 0.1 4.5 2 1 1 4 4 3 2 Uncharacterized protein conserved in bacteria (DUF2225) AAA_16 PF13191.1 OAP54709.1 - 1.6e-06 28.2 0.4 6.1e-06 26.3 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain TPR_21 PF09976.4 OAP54709.1 - 1.6e-06 28.0 8.0 29 4.5 1.0 7.9 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAP54709.1 - 2.1e-06 27.9 31.5 0.053 13.8 1.1 6.3 1 1 8 9 9 9 6 Tetratricopeptide repeat Tcf25 PF04910.9 OAP54709.1 - 5.6e-06 25.5 0.5 6 5.7 0.0 5.8 1 1 7 8 8 8 0 Transcriptional repressor TCF25 Arch_ATPase PF01637.13 OAP54709.1 - 0.0005 19.8 0.0 0.00077 19.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 OAP54709.1 - 0.0047 17.0 0.0 0.02 15.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF1107 PF06526.7 OAP54709.1 - 0.0093 15.7 0.0 1.5e+02 2.2 0.0 5.7 7 0 0 7 7 7 0 Protein of unknown function (DUF1107) Imm27 PF15573.1 OAP54709.1 - 0.015 14.5 1.4 2 7.5 0.0 4.5 3 2 4 7 7 7 0 Immunity protein 27 YwhD PF08741.5 OAP54709.1 - 0.14 11.5 0.3 0.37 10.1 0.1 1.7 2 0 0 2 2 2 0 YwhD family Glyoxalase_4 PF13669.1 OAP54710.1 - 0.015 15.2 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cu-oxidase_3 PF07732.10 OAP54711.1 - 2.7e-42 143.2 10.3 1.9e-41 140.4 0.7 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP54711.1 - 1.7e-40 137.6 7.9 2.1e-37 127.7 1.4 4.0 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 OAP54711.1 - 1.7e-35 122.2 1.8 3.6e-29 101.7 0.0 3.1 4 0 0 4 4 4 2 Multicopper oxidase AATF-Che1 PF13339.1 OAP54715.1 - 8.7e-31 106.7 0.8 8.7e-31 106.7 0.5 2.2 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 OAP54715.1 - 7.7e-27 93.2 0.0 1.8e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Rad4 PF03835.10 OAP54716.1 - 1.6e-35 121.6 0.1 1.6e-35 121.6 0.1 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 OAP54716.1 - 5.3e-27 93.3 0.2 9.2e-27 92.5 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 OAP54716.1 - 4.5e-18 64.5 0.1 8.2e-18 63.6 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 OAP54716.1 - 7.9e-13 48.5 2.0 1e-12 48.1 0.1 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 OAP54716.1 - 0.0022 18.1 0.0 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 Transglutaminase-like superfamily PTPA PF03095.10 OAP54719.1 - 1.6e-108 362.3 0.0 2e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Pap_E4 PF02711.9 OAP54719.1 - 0.054 14.3 0.6 0.054 14.3 0.4 1.9 2 0 0 2 2 2 0 E4 protein DUF572 PF04502.8 OAP54720.1 - 1.1e-45 156.3 0.0 1.9e-44 152.1 0.0 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF572) Nucleo_P87 PF07267.6 OAP54720.1 - 4.5 5.8 6.4 6.9 5.2 4.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-C3HC4 PF00097.20 OAP54721.1 - 0.00048 19.7 5.3 0.029 14.0 0.3 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP54721.1 - 0.00064 19.3 1.8 0.00064 19.3 1.3 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAP54721.1 - 0.0017 18.3 10.7 0.053 13.5 1.8 3.3 2 2 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAP54721.1 - 0.0028 17.3 2.2 0.048 13.3 0.3 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 OAP54721.1 - 0.0086 15.8 7.8 0.053 13.3 0.9 2.8 2 0 0 2 2 2 1 Ring finger domain FYVE PF01363.16 OAP54721.1 - 0.11 12.4 11.4 0.048 13.5 1.2 3.3 1 1 1 2 2 2 0 FYVE zinc finger Atg14 PF10186.4 OAP54721.1 - 0.18 10.7 3.4 0.25 10.2 2.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Carboxyl_trans PF01039.17 OAP54721.1 - 0.91 7.7 3.3 1.6 7.0 2.3 1.3 1 0 0 1 1 1 0 Carboxyl transferase domain Prok-RING_4 PF14447.1 OAP54721.1 - 0.98 9.0 6.7 0.086 12.4 0.9 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 OAP54721.1 - 5.4 6.9 11.9 2.2 8.1 2.1 3.3 2 1 0 2 2 2 0 Double zinc ribbon Sedlin_N PF04628.8 OAP54722.1 - 8.8e-39 132.3 0.0 1e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 OAP54722.1 - 5.2e-07 29.4 0.0 8.2e-05 22.3 0.0 2.1 1 1 1 2 2 2 2 Sybindin-like family DUF2040 PF09745.4 OAP54723.1 - 9.3e-39 132.1 18.8 9.3e-39 132.1 13.1 4.2 2 2 2 4 4 4 2 Coiled-coil domain-containing protein 55 (DUF2040) adh_short PF00106.20 OAP54724.1 - 9.7e-31 106.9 1.7 1.3e-30 106.5 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP54724.1 - 1.1e-13 51.3 1.1 1.5e-13 50.8 0.8 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP54724.1 - 1.9e-12 47.5 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP54724.1 - 4.6e-05 22.9 0.1 0.0001 21.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP54724.1 - 0.033 13.9 0.2 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ins_P5_2-kin PF06090.7 OAP54725.1 - 1.8e-40 138.9 0.0 6.6e-40 137.0 0.0 1.7 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ank PF00023.25 OAP54727.1 - 1.1e-103 334.1 12.2 9.6e-11 40.9 0.0 14.3 14 0 0 14 14 14 13 Ankyrin repeat Ank_2 PF12796.2 OAP54727.1 - 4.3e-101 331.4 12.1 7.4e-19 67.8 0.1 6.9 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP54727.1 - 1.5e-88 289.7 27.0 4.3e-11 43.0 0.0 10.5 2 1 10 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP54727.1 - 1.4e-76 244.6 3.7 1.8e-07 30.7 0.0 14.2 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.1 OAP54727.1 - 1.4e-72 238.0 19.1 3.3e-11 43.0 0.1 11.0 3 2 9 12 12 12 11 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 OAP54727.1 - 2e-15 56.4 0.0 3.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily DUF482 PF04339.7 OAP54727.1 - 0.05 12.4 0.0 0.43 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF482 CBM_21 PF03370.8 OAP54731.1 - 1.6e-37 127.9 1.7 3.7e-37 126.7 1.2 1.7 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit MCM PF00493.18 OAP54732.1 - 3.3e-139 463.3 0.0 4.4e-139 462.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAP54732.1 - 2e-25 89.6 0.0 6.9e-25 87.8 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAP54732.1 - 2.9e-06 26.6 0.0 0.00013 21.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAP54732.1 - 1.5e-05 24.7 0.0 4.1e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAP54732.1 - 0.0017 17.9 0.0 0.0044 16.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 OAP54733.1 - 5.3e-63 206.8 24.6 1.5e-10 40.5 1.3 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 OAP54733.1 - 9.8e-14 50.8 0.4 1.9e-13 49.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP54733.1 - 1e-12 47.3 0.3 2.2e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 OAP54733.1 - 8.6e-10 37.3 9.8 0.0095 14.1 0.1 5.8 3 1 3 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAP54733.1 - 0.0061 15.3 0.2 2.3 6.8 0.0 3.2 3 1 0 3 3 3 2 Nup133 N terminal like APG17 PF04108.7 OAP54734.1 - 1.8e-92 310.3 4.1 2.1e-92 310.1 2.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 NPV_P10 PF05531.7 OAP54734.1 - 0.086 13.0 6.8 1.9 8.7 0.1 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 OAP54734.1 - 0.16 11.8 11.8 0.55 10.0 0.4 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.8 OAP54734.1 - 0.19 11.3 9.6 3 7.5 0.2 4.2 4 1 0 4 4 4 0 Nsp1-like C-terminal region FH2 PF02181.18 OAP54734.1 - 0.31 9.8 8.1 1.5 7.5 0.0 3.2 2 2 1 3 3 3 0 Formin Homology 2 Domain Baculo_PEP_C PF04513.7 OAP54734.1 - 0.73 9.6 12.0 3.9 7.2 0.1 4.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 OAP54734.1 - 1.5 8.3 12.3 0.53 9.8 0.1 3.4 3 3 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WXG100 PF06013.7 OAP54734.1 - 2.2 8.3 13.2 8.4 6.4 0.1 4.7 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Exonuc_VII_L PF02601.10 OAP54734.1 - 2.7 7.1 7.8 1.3 8.1 1.3 2.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit Snapin_Pallidin PF14712.1 OAP54734.1 - 3.9 7.8 17.4 1.7 8.9 0.4 4.2 4 0 0 4 4 4 0 Snapin/Pallidin Laminin_II PF06009.7 OAP54734.1 - 7.5 6.3 15.0 2.2 8.0 0.3 3.5 4 0 0 4 4 4 0 Laminin Domain II RIO1 PF01163.17 OAP54735.1 - 3.7e-70 235.1 1.2 3.7e-70 235.1 0.8 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 OAP54735.1 - 0.02 14.6 6.8 3 7.5 0.0 3.8 3 2 1 4 4 4 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 OAP54735.1 - 0.054 12.5 0.3 1.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase adh_short PF00106.20 OAP54736.1 - 8.3e-24 84.3 0.1 1.8e-23 83.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP54736.1 - 8.2e-10 38.6 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP54736.1 - 2.2e-07 30.8 0.0 3.1e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAP54736.1 - 0.0016 18.4 0.0 0.005 16.8 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding FAD_binding_3 PF01494.14 OAP54737.1 - 3.2e-50 171.1 0.0 4.8e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP54737.1 - 7.4e-08 32.5 0.0 1.9e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP54737.1 - 9.4e-08 31.3 0.1 6.5e-06 25.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP54737.1 - 5e-07 29.9 0.0 1.3e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP54737.1 - 2.8e-06 27.6 0.0 0.00049 20.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP54737.1 - 3.9e-06 25.6 0.2 0.00081 17.9 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 OAP54737.1 - 3.8e-05 22.9 0.2 0.34 9.9 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP54737.1 - 5.7e-05 23.0 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP54737.1 - 7.1e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 OAP54737.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP54737.1 - 0.0011 17.8 0.0 0.0037 16.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 OAP54737.1 - 0.0025 17.0 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 OAP54737.1 - 0.0028 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family K_oxygenase PF13434.1 OAP54737.1 - 0.0039 16.1 0.0 0.88 8.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 OAP54737.1 - 0.0048 16.8 0.1 0.012 15.5 0.0 1.7 2 0 0 2 2 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 OAP54737.1 - 0.0058 16.2 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 OAP54737.1 - 0.0058 15.5 0.1 0.011 14.5 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 OAP54737.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 OAP54737.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.7 OAP54737.1 - 0.018 13.9 0.2 0.039 12.8 0.2 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 OAP54737.1 - 0.019 15.2 0.1 0.14 12.3 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF730 PF05325.6 OAP54737.1 - 0.025 14.4 0.1 0.059 13.1 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF730) ApbA PF02558.11 OAP54737.1 - 0.055 12.9 0.1 0.11 11.8 0.0 1.6 2 0 0 2 2 1 0 Ketopantoate reductase PanE/ApbA Mqo PF06039.10 OAP54737.1 - 0.056 11.6 0.0 0.21 9.7 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 OAP54737.1 - 0.083 12.6 0.1 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP54738.1 - 1.8e-20 73.6 2.5 3e-09 37.0 0.0 4.5 2 2 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP54738.1 - 1.1e-17 64.1 0.2 3.5e-14 52.9 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP54738.1 - 5.1e-13 48.6 6.0 1.1e-05 24.5 0.0 4.1 2 2 2 5 5 5 3 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP54738.1 - 1.2e-10 40.8 0.1 0.00033 19.6 0.0 3.2 2 1 1 3 3 3 3 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP54738.1 - 7.9e-09 35.8 0.0 0.00011 22.3 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP54738.1 - 4.4e-08 32.2 0.1 0.2 10.2 0.0 3.3 3 0 0 3 3 3 3 Tryptophan halogenase K_oxygenase PF13434.1 OAP54738.1 - 4.6e-08 32.3 0.0 5.9e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP54738.1 - 8.3e-07 28.9 0.0 0.0026 17.7 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP54738.1 - 1.3e-06 27.1 0.5 0.071 11.5 0.1 3.7 3 1 1 4 4 4 3 HI0933-like protein NAD_binding_9 PF13454.1 OAP54738.1 - 4.6e-06 26.4 1.5 0.3 10.8 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding FAD_oxidored PF12831.2 OAP54738.1 - 4.1e-05 22.8 1.3 0.5 9.3 0.0 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase TrkA_N PF02254.13 OAP54738.1 - 8.6e-05 22.5 0.1 0.025 14.5 0.0 3.1 2 1 0 2 2 2 1 TrkA-N domain FAD_binding_3 PF01494.14 OAP54738.1 - 0.0013 17.9 1.9 0.011 14.8 0.0 2.8 2 1 1 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.19 OAP54738.1 - 0.0032 16.3 0.0 0.35 9.6 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 OAP54738.1 - 0.021 13.6 4.3 1.2 7.9 1.7 3.5 3 1 1 4 4 4 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 OAP54738.1 - 0.027 13.5 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase CheB_methylest PF01339.12 OAP54738.1 - 0.036 13.4 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 CheB methylesterase Thi4 PF01946.12 OAP54738.1 - 0.075 12.1 0.0 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 OAP54738.1 - 0.12 12.1 0.0 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Nbl1_Borealin_N PF10444.4 OAP54738.1 - 0.2 11.0 0.2 0.64 9.4 0.1 1.8 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Caps_synth PF05704.7 OAP54739.1 - 1.5e-11 43.9 0.0 4e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 OAP54739.1 - 2.3e-06 27.9 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SMC_N PF02463.14 OAP54740.1 - 1.1e-54 185.0 34.9 4.9e-54 182.8 24.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAP54740.1 - 2.1e-27 95.5 0.1 1.6e-26 92.6 0.0 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 OAP54740.1 - 7e-15 55.8 31.5 7e-15 55.8 21.8 6.6 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 OAP54740.1 - 5.6e-14 52.7 0.6 1.2e-05 25.3 0.3 2.7 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 OAP54740.1 - 1.5e-11 44.0 0.2 1.8e-07 30.6 0.0 4.0 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 OAP54740.1 - 0.0013 18.1 0.0 0.0033 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 OAP54740.1 - 0.085 11.3 0.0 0.085 11.3 0.0 5.8 3 2 0 5 5 5 0 AAA domain UPF0184 PF03670.8 OAP54740.1 - 6 7.1 26.9 0.16 12.1 1.8 6.1 5 1 1 6 6 6 0 Uncharacterised protein family (UPF0184) CTP_synth_N PF06418.9 OAP54741.1 - 1.1e-110 369.0 0.1 1.6e-110 368.5 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 OAP54741.1 - 2.4e-55 186.9 0.0 3.8e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 OAP54741.1 - 5.9e-08 32.4 0.0 1.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 OAP54741.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NicO PF03824.11 OAP54742.1 - 2.4e-55 187.8 16.3 8.3e-53 179.5 5.9 2.4 2 0 0 2 2 2 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 OAP54742.1 - 1.3 7.7 5.5 0.33 9.7 1.3 1.8 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Methyltransf_23 PF13489.1 OAP54743.1 - 1.7e-18 66.8 0.0 4.1e-18 65.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP54743.1 - 2.7e-10 40.6 0.0 5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP54743.1 - 3e-08 34.2 0.0 5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP54743.1 - 2.6e-07 31.0 0.0 4.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP54743.1 - 4.2e-06 26.4 0.0 9.5e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP54743.1 - 0.00031 20.7 0.0 0.00068 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP54743.1 - 0.00053 20.3 0.0 0.00091 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP54743.1 - 0.061 12.4 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 OAP54743.1 - 0.09 11.7 0.0 0.2 10.6 0.0 1.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family NodS PF05401.6 OAP54743.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) PEP-utilizers PF00391.18 OAP54743.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain AAA_10 PF12846.2 OAP54744.1 - 4.3e-08 32.9 0.3 0.00055 19.4 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 OAP54744.1 - 0.00039 20.5 0.0 0.59 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAP54744.1 - 0.0014 17.8 0.0 0.0028 16.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Zot PF05707.7 OAP54744.1 - 0.0048 16.3 0.2 0.034 13.6 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF853 PF05872.7 OAP54744.1 - 0.047 12.0 0.1 0.15 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA PF00004.24 OAP54744.1 - 0.14 12.3 0.8 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CENP-B_dimeris PF09026.5 OAP54744.1 - 0.35 11.1 5.2 0.98 9.6 0.4 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.7 OAP54744.1 - 0.63 9.7 7.9 4.4 6.9 0.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 OAP54744.1 - 5.5 7.3 11.5 0.77 10.0 3.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 OAP54745.1 - 4.5e-12 45.6 0.0 4.4e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF2602 PF10782.4 OAP54746.1 - 0.48 10.2 2.5 1.3 8.9 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2602) FAD_binding_4 PF01565.18 OAP54750.1 - 3.5e-16 58.9 4.4 1.8e-15 56.6 2.8 2.4 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAP54750.1 - 1.9e-11 43.6 1.0 1e-10 41.3 0.1 2.4 2 0 0 2 2 2 1 Berberine and berberine like zf-Nse PF11789.3 OAP54751.1 - 3.5e-16 58.4 0.1 8.1e-16 57.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 OAP54751.1 - 1.7e-06 27.8 0.1 0.00073 19.4 0.0 2.5 1 1 1 2 2 2 2 U-box domain DUF913 PF06025.7 OAP54751.1 - 8.6 4.9 6.3 17 4.0 3.5 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF913) Patched PF02460.13 OAP54752.1 - 6.5e-73 245.9 7.4 4.5e-72 243.1 5.0 2.1 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 OAP54752.1 - 5.5e-50 168.8 6.8 5.5e-50 168.8 4.7 3.0 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 OAP54752.1 - 4.7e-07 28.8 24.1 0.00013 20.7 5.9 2.4 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.14 OAP54752.1 - 0.035 11.5 12.1 0.062 10.7 8.4 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family CaM_bdg_C0 PF10562.4 OAP54752.1 - 0.13 12.1 0.6 0.26 11.1 0.4 1.5 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF2433 PF10360.4 OAP54753.1 - 7.6e-49 165.3 0.0 1.2e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 OAP54753.1 - 0.0024 17.2 0.0 0.0052 16.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP54753.1 - 0.0082 15.9 0.0 0.024 14.4 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PAP1 PF08601.5 OAP54754.1 - 1.8e-58 198.9 18.4 1.8e-58 198.9 12.8 3.4 2 2 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 OAP54754.1 - 5.5e-09 35.8 9.2 1.2e-08 34.7 6.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP54754.1 - 0.028 14.2 14.0 0.26 11.1 9.7 2.4 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.12 OAP54754.1 - 0.058 13.7 8.4 0.15 12.4 5.9 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 OAP54754.1 - 0.058 12.9 2.8 0.11 12.0 1.9 1.4 1 0 0 1 1 1 0 IncA protein Adeno_PIX PF03955.9 OAP54754.1 - 0.12 12.9 2.7 0.12 12.9 0.4 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) TUDOR PF00567.19 OAP54755.1 - 0.00038 20.2 0.0 0.0022 17.8 0.0 2.0 2 0 0 2 2 2 1 Tudor domain Fis1_TPR_C PF14853.1 OAP54755.1 - 0.029 14.2 0.7 0.053 13.3 0.5 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TBPIP PF07106.8 OAP54755.1 - 0.056 12.9 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4537 PF15057.1 OAP54755.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) TP2 PF01254.13 OAP54755.1 - 0.33 11.2 4.0 0.7 10.2 2.8 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 Ribosomal_60s PF00428.14 OAP54755.1 - 3.9 7.9 6.7 11 6.5 1.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Tmemb_170 PF10190.4 OAP54756.1 - 0.024 14.6 1.5 0.024 14.6 1.1 2.0 2 0 0 2 2 2 0 Putative transmembrane protein 170 Acyl-CoA_dh_N PF02771.11 OAP54756.1 - 0.082 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain SseC PF04888.7 OAP54756.1 - 2.3 7.4 4.1 3.7 6.7 2.8 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family PRA1 PF03208.14 OAP54756.1 - 4.4 6.6 6.2 9.9 5.4 4.3 1.7 1 1 0 1 1 1 0 PRA1 family protein COesterase PF00135.23 OAP54757.1 - 6.8e-91 305.5 0.3 3.3e-82 276.9 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP54757.1 - 6.5e-11 42.2 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP54757.1 - 7.4e-05 22.5 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP54757.1 - 0.029 14.2 0.2 0.047 13.5 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP54757.1 - 0.049 13.1 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UBN2 PF14223.1 OAP54758.1 - 1.7e-07 30.9 1.4 2.9e-07 30.2 0.1 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAP54758.1 - 4.9e-07 29.3 0.0 2.5e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 OAP54758.1 - 6.5e-06 25.7 0.6 0.00012 21.6 0.5 2.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type adh_short PF00106.20 OAP54759.1 - 1.4e-28 99.8 1.9 1.8e-28 99.5 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54759.1 - 7.8e-28 97.8 0.1 9.8e-28 97.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54759.1 - 7.4e-15 55.0 0.4 1.1e-14 54.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP54759.1 - 0.014 14.7 0.3 0.041 13.3 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family S4 PF01479.20 OAP54759.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 S4 domain Eno-Rase_NADH_b PF12242.3 OAP54759.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GST_N_3 PF13417.1 OAP54760.1 - 1e-10 41.6 0.1 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP54760.1 - 2.1e-09 37.2 0.0 3.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP54760.1 - 0.00014 21.6 0.3 0.00029 20.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PAS_9 PF13426.1 OAP54760.1 - 0.014 15.7 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 OAP54760.1 - 0.047 13.7 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold Glyco_hydro_31 PF01055.21 OAP54761.1 - 2.4e-113 379.3 1.0 3.1e-113 378.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 OAP54761.1 - 3.5e-19 68.4 1.4 4.9e-18 64.7 0.1 3.6 5 0 0 5 5 5 1 Galactose mutarotase-like Sugar_tr PF00083.19 OAP54762.1 - 4.6e-72 243.0 25.7 5.3e-72 242.8 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP54762.1 - 1.3e-19 70.1 29.2 1.3e-19 70.1 20.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAP54762.1 - 5e-06 25.1 30.6 0.00022 19.7 1.7 3.2 3 1 0 3 3 3 2 MFS/sugar transport protein adh_short PF00106.20 OAP54763.1 - 3.1e-24 85.7 0.6 2.3e-23 82.9 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54763.1 - 1.9e-18 67.1 0.4 2.8e-17 63.2 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54763.1 - 7.7e-10 38.7 0.7 1.3e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 OAP54763.1 - 1.1e-05 25.5 0.0 2.4e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 OAP54763.1 - 0.0003 20.8 1.1 0.01 15.8 0.1 2.8 1 1 1 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAP54763.1 - 0.00062 18.7 0.1 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.8 OAP54763.1 - 0.0072 15.7 0.0 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Epimerase PF01370.16 OAP54763.1 - 0.011 15.2 0.4 0.07 12.5 0.1 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 OAP54763.1 - 0.013 14.6 0.1 0.099 11.7 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 OAP54763.1 - 0.014 15.8 0.1 0.036 14.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAP54763.1 - 0.052 13.1 0.1 0.17 11.5 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 OAP54763.1 - 0.067 12.6 0.1 0.49 9.8 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.21 OAP54763.1 - 0.068 12.7 0.1 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase STAT_int PF02865.12 OAP54763.1 - 0.08 12.9 0.0 3.1 7.7 0.0 2.2 1 1 1 2 2 2 0 STAT protein, protein interaction domain MFS_1 PF07690.11 OAP54764.1 - 1.7e-39 135.5 61.3 3.5e-39 134.5 39.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP54764.1 - 2.2e-09 36.1 25.3 2.2e-09 36.1 17.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 OAP54765.1 - 8.9e-22 77.7 0.0 1.4e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54765.1 - 4.8e-19 69.0 0.0 4.8e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54765.1 - 4.1e-09 36.3 0.0 7.6e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP54765.1 - 0.00082 19.1 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 OAP54765.1 - 0.0038 16.4 0.1 0.0058 15.8 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 OAP54765.1 - 0.044 13.1 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Apolipoprotein PF01442.13 OAP54766.1 - 3e-05 23.6 2.4 6.4e-05 22.5 1.7 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain AAA_13 PF13166.1 OAP54766.1 - 0.00099 17.6 3.1 0.0015 17.1 2.1 1.2 1 0 0 1 1 1 1 AAA domain Baculo_PEP_C PF04513.7 OAP54766.1 - 0.014 15.2 3.2 0.034 13.9 1.4 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 OAP54766.1 - 0.031 12.9 8.1 0.047 12.3 4.7 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein PilJ PF13675.1 OAP54766.1 - 0.036 14.3 8.2 0.37 11.1 0.1 3.7 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term PhageMin_Tail PF10145.4 OAP54766.1 - 0.076 12.6 0.1 0.076 12.6 0.0 2.7 3 1 0 3 3 2 0 Phage-related minor tail protein MinE PF03776.9 OAP54766.1 - 0.08 12.4 0.4 0.41 10.1 0.1 2.1 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE NPV_P10 PF05531.7 OAP54766.1 - 0.19 12.0 4.3 7.9 6.8 0.0 3.7 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein Rootletin PF15035.1 OAP54766.1 - 0.19 11.6 8.6 1.3 8.9 5.9 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 OAP54766.1 - 0.21 10.7 6.4 0.61 9.2 3.8 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Sec34 PF04136.10 OAP54766.1 - 0.26 11.0 3.4 0.63 9.7 0.1 2.4 1 1 1 2 2 2 0 Sec34-like family Fib_alpha PF08702.5 OAP54766.1 - 0.26 11.4 7.3 0.11 12.5 3.0 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MerR-DNA-bind PF09278.6 OAP54766.1 - 0.43 11.0 8.3 1.9 8.9 0.0 4.1 3 1 1 4 4 4 0 MerR, DNA binding TPR_MLP1_2 PF07926.7 OAP54766.1 - 0.48 10.1 9.5 0.67 9.7 5.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 OAP54766.1 - 0.53 8.6 1.2 0.75 8.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 OAP54766.1 - 0.94 9.2 5.1 3.2 7.5 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DivIVA PF05103.8 OAP54766.1 - 1 9.3 6.0 42 4.1 4.1 3.0 1 1 0 1 1 1 0 DivIVA protein Prefoldin_2 PF01920.15 OAP54766.1 - 1.3 8.8 5.5 1.4 8.6 0.2 2.7 3 0 0 3 3 2 0 Prefoldin subunit TMF_DNA_bd PF12329.3 OAP54766.1 - 1.7 8.5 8.2 2.4 8.0 0.1 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CorA PF01544.13 OAP54766.1 - 1.8 7.5 7.0 1.9 7.4 3.2 2.1 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein IncA PF04156.9 OAP54766.1 - 2.1 7.9 9.0 7.4 6.1 6.3 2.0 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 OAP54766.1 - 4.5 7.1 10.8 0.62 9.9 4.2 2.0 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding Fungal_trans PF04082.13 OAP54767.1 - 1.2e-16 60.3 0.1 1.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54767.1 - 1.6e-08 34.2 10.0 3e-08 33.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Utp14 PF04615.8 OAP54770.1 - 9.3 4.2 7.9 11 4.0 5.5 1.1 1 0 0 1 1 1 0 Utp14 protein DPPIV_N PF00930.16 OAP54771.1 - 3.9e-101 338.1 0.0 5.4e-101 337.7 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 OAP54771.1 - 4.7e-55 186.0 1.0 9.4e-55 185.1 0.6 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP54771.1 - 3.6e-09 36.5 0.0 7.8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP54771.1 - 2.2e-06 27.7 0.1 0.00011 22.1 0.1 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAP54771.1 - 6.7e-06 25.7 1.6 5.2e-05 22.7 0.5 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 OAP54771.1 - 0.0043 16.5 0.1 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 Putative esterase DLH PF01738.13 OAP54771.1 - 0.0056 15.9 0.0 0.035 13.3 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF948 PF06103.6 OAP54773.1 - 0.019 14.8 11.1 0.1 12.4 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 OAP54773.1 - 0.048 13.4 9.2 0.35 10.6 3.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KAR PF15222.1 OAP54773.1 - 0.59 10.2 8.7 1.3 9.1 0.6 2.6 1 1 1 2 2 2 0 Kidney androgen-regulated Ribosomal_60s PF00428.14 OAP54773.1 - 0.63 10.4 23.9 0.52 10.7 9.4 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein NPV_P10 PF05531.7 OAP54773.1 - 1 9.6 7.5 15 5.9 3.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RXT2_N PF08595.6 OAP54773.1 - 1.2 8.9 14.8 1.4 8.7 4.0 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 OAP54773.1 - 9 6.6 22.0 4.3 7.6 7.9 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Voltage_CLC PF00654.15 OAP54775.1 - 1.6e-92 310.2 22.7 1.6e-92 310.2 15.7 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 OAP54775.1 - 0.012 15.5 2.0 0.012 15.5 1.4 3.4 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence Lipase_GDSL_2 PF13472.1 OAP54776.1 - 2.4e-23 83.2 0.0 2.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 OAP54776.1 - 2.7e-22 79.7 0.0 3.4e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase eIF-5_eIF-2B PF01873.12 OAP54777.1 - 1.6e-38 131.1 0.0 2.5e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 OAP54777.1 - 9.8e-24 83.1 0.2 9.8e-24 83.1 0.1 1.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon HK PF02110.10 OAP54778.1 - 1.6e-77 259.9 0.4 2.9e-77 259.1 0.3 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 OAP54778.1 - 9.8e-60 200.7 2.6 2.1e-59 199.6 1.8 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 OAP54778.1 - 0.00091 18.5 0.1 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 OAP54778.1 - 0.0016 17.6 0.0 0.0043 16.2 0.0 1.8 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peripla_BP_6 PF13458.1 OAP54778.1 - 0.0019 17.6 0.3 0.0056 16.0 0.1 1.9 2 0 0 2 2 2 1 Periplasmic binding protein ACPS PF01648.15 OAP54779.1 - 1.3e-08 34.6 0.2 1.2e-07 31.5 0.1 2.5 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 OAP54780.1 - 3e-55 186.7 0.0 5.3e-45 153.3 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 OAP54780.1 - 3.6e-10 39.6 0.0 2.6e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 OAP54780.1 - 1.1e-05 24.8 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 OAP54780.1 - 6.7e-05 22.4 0.1 0.0004 19.9 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 OAP54780.1 - 9.5e-05 21.7 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase RRM_1 PF00076.17 OAP54781.1 - 6.4e-16 57.7 0.0 9.8e-16 57.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP54781.1 - 8.3e-13 48.1 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP54781.1 - 1.6e-08 34.2 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TauD PF02668.11 OAP54782.1 - 6.1e-39 134.2 0.2 7.7e-39 133.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 OAP54783.1 - 9.9e-32 110.0 23.9 9.9e-32 110.0 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP54783.1 - 1.6e-05 24.6 0.4 4.8e-05 23.0 0.3 1.8 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.11 OAP54784.1 - 7.9e-34 116.9 25.5 1.2e-33 116.3 16.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily VIT1 PF01988.14 OAP54784.1 - 0.066 12.6 0.6 0.14 11.6 0.0 1.8 1 1 0 1 1 1 0 VIT family DUF3894 PF13033.1 OAP54784.1 - 2.9 7.9 8.7 4 7.5 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3894) Lipoprotein_20 PF13942.1 OAP54785.1 - 0.033 13.7 1.8 0.061 12.8 1.2 1.3 1 0 0 1 1 1 0 YfhG lipoprotein DUF3584 PF12128.3 OAP54785.1 - 0.17 9.1 6.8 0.28 8.4 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SlyX PF04102.7 OAP54785.1 - 1.1 9.7 5.1 1 9.7 0.7 2.9 2 0 0 2 2 2 0 SlyX DNA_pol_E_B PF04042.11 OAP54786.1 - 2.1e-46 157.8 0.0 3e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.4 OAP54787.1 - 3.5e-13 48.5 0.4 3.5e-13 48.5 0.3 2.0 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 OAP54787.1 - 5.4e-05 22.7 9.9 0.0028 17.2 1.5 3.0 3 1 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 OAP54787.1 - 0.0095 15.8 12.3 0.066 13.1 2.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAP54787.1 - 0.018 15.7 2.3 0.032 14.9 0.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CagE_TrbE_VirB PF03135.9 OAP54787.1 - 0.068 12.9 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system TPR_3 PF07720.7 OAP54787.1 - 2 8.3 5.7 0.36 10.6 0.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribonuc_L-PSP PF01042.16 OAP54788.1 - 1.9e-19 69.5 0.0 2.2e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 OAP54789.1 - 3.1e-23 81.9 0.2 4.6e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54789.1 - 3.1e-07 30.1 11.0 3.1e-07 30.1 7.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylesterase PF01731.15 OAP54790.1 - 2.3e-06 27.4 0.1 0.00011 22.0 0.0 2.8 2 1 0 2 2 2 1 Arylesterase Misat_Tub_SegII PF10644.4 OAP54790.1 - 0.0065 16.5 0.6 0.013 15.4 0.4 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain PQQ_3 PF13570.1 OAP54790.1 - 0.04 14.2 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain EIIBC-GUT_N PF03612.9 OAP54790.1 - 0.043 13.4 3.2 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus NHL PF01436.16 OAP54790.1 - 0.06 13.3 0.2 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 NHL repeat SUFU_C PF12470.3 OAP54790.1 - 0.14 11.7 2.6 0.24 10.9 1.8 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain RNA_polI_A34 PF08208.6 OAP54790.1 - 9.8 5.7 30.6 15 5.1 21.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 COesterase PF00135.23 OAP54791.1 - 1.6e-57 195.4 0.0 1.8e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP54791.1 - 3.9e-09 36.3 0.1 0.00019 21.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP54791.1 - 0.0041 16.8 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP54791.1 - 0.0073 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAP54791.1 - 0.021 14.7 0.1 0.064 13.1 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 OAP54792.1 - 6.9e-22 77.6 14.2 6.9e-22 77.6 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP54792.1 - 0.00039 18.7 1.9 0.00039 18.7 1.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DAO PF01266.19 OAP54793.1 - 1.9e-46 158.6 0.1 4e-46 157.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP54793.1 - 2.9e-08 32.9 2.2 5e-07 28.9 1.5 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAP54793.1 - 9.6e-07 28.2 0.1 4.7e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP54793.1 - 0.00016 21.5 0.1 0.00043 20.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP54793.1 - 0.0026 17.7 0.1 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 OAP54793.1 - 0.0066 16.1 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 OAP54793.1 - 0.014 15.8 0.3 0.035 14.5 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP54793.1 - 0.014 14.3 0.1 0.082 11.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 OAP54793.1 - 0.017 13.6 0.1 0.028 12.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 OAP54793.1 - 0.085 11.7 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP54793.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP54793.1 - 0.16 11.0 0.1 0.31 10.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family MIP PF00230.15 OAP54794.1 - 7.9e-55 185.7 7.0 1e-54 185.4 4.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.11 OAP54795.1 - 7e-74 247.7 0.4 1.7e-73 246.4 0.3 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 OAP54795.1 - 4.3e-67 225.9 0.0 5.7e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FAD_binding_3 PF01494.14 OAP54796.1 - 2.7e-24 85.9 1.0 4.8e-24 85.0 0.7 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP54796.1 - 1.1e-11 44.3 3.0 2.8e-07 29.7 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAP54796.1 - 5.6e-07 28.5 6.1 0.00021 20.0 0.2 2.7 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 OAP54796.1 - 1.3e-06 28.2 1.6 3.2e-06 27.0 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP54796.1 - 4.3e-06 25.8 3.7 0.0013 17.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP54796.1 - 4.9e-06 25.6 3.4 9.4e-06 24.7 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 OAP54796.1 - 1.3e-05 24.5 2.5 0.016 14.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 OAP54796.1 - 3.5e-05 23.7 1.6 0.00015 21.7 1.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP54796.1 - 0.0013 19.0 2.7 0.0029 17.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP54796.1 - 0.0019 17.3 0.4 0.0035 16.4 0.3 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 OAP54796.1 - 0.002 16.6 2.4 0.003 16.1 0.7 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 OAP54796.1 - 0.0029 16.7 0.9 0.0045 16.1 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP54796.1 - 0.0092 15.7 2.1 2.3 7.9 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 OAP54796.1 - 0.011 14.6 2.9 0.019 13.8 2.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAP54796.1 - 0.013 15.5 1.0 0.091 12.8 0.7 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 OAP54796.1 - 0.029 14.0 0.5 0.05 13.2 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 OAP54796.1 - 0.081 12.2 0.4 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 OAP54796.1 - 0.17 11.4 0.5 0.3 10.6 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DWNN PF08783.6 OAP54797.1 - 7e-21 73.9 0.3 1.9e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 DWNN domain U-box PF04564.10 OAP54797.1 - 2.4e-06 27.4 0.0 1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-CCHC_2 PF13696.1 OAP54797.1 - 0.00033 20.0 2.6 0.00033 20.0 1.8 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 OAP54797.1 - 0.00044 20.0 2.5 0.00093 19.0 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAP54797.1 - 0.0084 15.8 0.4 0.025 14.3 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 OAP54797.1 - 0.015 15.3 8.0 0.015 15.3 5.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP54797.1 - 0.5 10.0 7.9 1.2 8.8 5.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAP54797.1 - 1.7 8.5 8.3 4.1 7.3 5.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Med3 PF11593.3 OAP54797.1 - 8.7 5.4 63.4 0.027 13.7 33.0 2.7 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal RabGAP-TBC PF00566.13 OAP54798.1 - 1.9e-46 158.2 0.0 6.5e-45 153.2 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RRM_1 PF00076.17 OAP54799.1 - 8.2e-38 127.8 0.2 8.9e-18 63.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP54799.1 - 1.9e-31 107.8 0.8 1.2e-16 60.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP54799.1 - 2e-16 59.5 0.0 7.5e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAP54799.1 - 0.022 14.6 0.1 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif TRP PF06011.7 OAP54800.1 - 1.4e-132 442.4 14.0 1.7e-132 442.0 9.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 OAP54800.1 - 4.2e-37 127.3 3.9 6.8e-37 126.6 2.7 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 OAP54800.1 - 1.6e-05 25.1 0.6 2.7e-05 24.4 0.4 1.4 1 0 0 1 1 1 1 ML domain Shisa PF13908.1 OAP54800.1 - 0.0094 16.1 4.7 0.058 13.5 0.0 2.8 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator DUF1153 PF06627.6 OAP54800.1 - 0.084 12.7 0.1 4.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) TMEM154 PF15102.1 OAP54800.1 - 1.4 8.5 5.9 7 6.3 0.7 2.5 2 0 0 2 2 2 0 TMEM154 protein family HemY_N PF07219.8 OAP54800.1 - 4.1 7.0 7.9 2 8.0 0.1 3.2 2 1 0 2 2 2 0 HemY protein N-terminus Glyco_hydro_cc PF11790.3 OAP54801.1 - 2.5e-57 194.0 0.0 3e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FAD_binding_6 PF00970.19 OAP54802.1 - 1.5e-28 98.8 0.0 2.3e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAP54802.1 - 3.1e-26 92.0 0.0 4.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 OAP54802.1 - 6.7e-05 22.8 0.0 0.0038 17.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 OAP54802.1 - 0.0029 17.5 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DsbD PF02683.10 OAP54802.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF3605 PF12239.3 OAP54803.1 - 5.9e-56 188.6 0.1 7e-56 188.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) tRNA-synt_1d PF00750.14 OAP54805.1 - 6.5e-79 265.3 9.9 7.3e-44 150.0 4.2 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 OAP54805.1 - 2.5e-31 108.1 0.6 5.9e-31 106.9 0.4 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 OAP54805.1 - 1.2e-07 32.1 2.2 2e-07 31.4 0.0 2.6 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain Myosin_tail_1 PF01576.14 OAP54806.1 - 0.0044 14.8 0.2 0.0053 14.5 0.2 1.0 1 0 0 1 1 1 1 Myosin tail Ank_2 PF12796.2 OAP54807.1 - 9.8e-106 346.3 11.4 5.7e-25 87.4 0.1 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP54807.1 - 1.2e-70 232.7 1.9 9.6e-12 45.0 0.0 6.8 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 OAP54807.1 - 1.6e-66 216.9 11.4 2.6e-07 30.0 0.0 8.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 OAP54807.1 - 1.2e-47 155.1 2.1 0.00016 21.6 0.0 9.0 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 OAP54807.1 - 3.4e-40 135.1 2.3 7.8e-06 25.9 0.1 9.5 2 1 7 9 9 9 8 Ankyrin repeats (many copies) gag-asp_proteas PF13975.1 OAP54807.1 - 8e-12 44.8 12.9 4.7 7.1 0.0 8.4 8 0 0 8 8 8 5 gag-polyprotein putative aspartyl protease DUF1843 PF08898.5 OAP54807.1 - 5.4e-07 29.5 15.9 0.43 10.6 0.2 6.8 4 3 2 6 6 6 3 Domain of unknown function (DUF1843) NACHT PF05729.7 OAP54807.1 - 4.3e-05 23.2 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RVP PF00077.15 OAP54807.1 - 0.00014 21.6 11.5 44 4.0 0.0 7.7 4 3 3 8 8 8 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAP54807.1 - 0.0021 18.5 2.8 18 5.9 0.0 6.3 2 1 3 6 6 6 0 Aspartyl protease AAA PF00004.24 OAP54807.1 - 0.1 12.8 0.0 1.1 9.4 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAP54807.1 - 0.78 9.6 6.3 0.13 12.2 0.3 2.6 3 1 0 3 3 3 0 AAA ATPase domain RrnaAD PF00398.15 OAP54809.1 - 6.3e-57 192.5 0.0 1.1e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 OAP54809.1 - 3.7e-09 36.6 0.0 6.2e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP54809.1 - 3.6e-05 24.3 0.0 6.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP54809.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 OAP54809.1 - 0.0013 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 OAP54809.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP54809.1 - 0.0043 17.4 0.0 0.0099 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAP54809.1 - 0.0065 15.5 0.0 0.0098 14.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 OAP54809.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 OAP54809.1 - 0.012 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 OAP54809.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 OAP54809.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PRP1_N PF06424.7 OAP54810.1 - 2.8e-49 166.8 4.7 7.3e-49 165.5 3.3 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 OAP54810.1 - 1.1e-30 103.2 38.2 2.4e-05 24.5 0.5 14.0 7 4 8 15 15 13 8 Tetratricopeptide repeat TPR_19 PF14559.1 OAP54810.1 - 4.9e-24 84.4 19.7 5.3e-08 33.0 0.3 9.4 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 OAP54810.1 - 1.3e-18 67.0 22.9 1.2e-05 25.7 2.3 8.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAP54810.1 - 6.8e-13 48.0 12.3 0.19 11.3 0.0 8.4 5 3 3 8 8 8 4 TPR repeat TPR_2 PF07719.12 OAP54810.1 - 3e-12 45.4 12.5 0.13 12.2 0.0 10.1 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAP54810.1 - 4.3e-10 38.9 3.8 2.7 8.4 0.0 10.0 9 2 2 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP54810.1 - 9.7e-08 31.2 0.0 0.065 13.0 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAP54810.1 - 8.7e-06 25.1 0.0 0.5 10.0 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 OAP54810.1 - 0.00061 18.9 30.4 0.0007 18.7 4.3 6.0 3 2 2 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.3 OAP54810.1 - 0.001 17.9 8.8 4 6.0 0.0 5.9 4 1 2 6 6 6 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 OAP54810.1 - 0.0031 17.8 11.0 1.1e+02 3.5 0.0 9.2 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP54810.1 - 0.0035 17.2 8.0 1.6 8.7 0.0 6.5 6 1 3 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP54810.1 - 0.0045 16.6 2.6 8 6.5 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Suf PF05843.9 OAP54810.1 - 0.035 13.8 0.0 3.4 7.3 0.0 3.2 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) DUF3808 PF10300.4 OAP54810.1 - 0.088 11.3 0.4 21 3.5 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) TPR_10 PF13374.1 OAP54810.1 - 1.6 8.7 5.8 47 4.0 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAP54810.1 - 6.8 6.6 15.3 2.5 8.0 0.3 5.8 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 OAP54810.1 - 8 6.3 21.2 0.11 12.3 1.1 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat GFA PF04828.9 OAP54811.1 - 1.1e-10 41.3 0.8 1.1e-10 41.3 0.6 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2_4 PF13894.1 OAP54812.1 - 0.0058 16.8 0.1 0.0058 16.8 0.1 7.1 9 0 0 9 9 9 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP54812.1 - 0.03 14.6 0.1 0.03 14.6 0.0 8.8 9 1 0 9 9 9 0 Zinc finger, C2H2 type Yippee-Mis18 PF03226.9 OAP54813.1 - 1.9e-23 82.3 0.8 3e-23 81.6 0.6 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 OAP54813.1 - 0.023 14.5 1.4 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I Transp_Tc5_C PF04236.10 OAP54813.1 - 0.16 12.2 0.9 1.4 9.2 0.3 2.2 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Ribosomal_S27e PF01667.12 OAP54813.1 - 0.24 10.9 2.7 12 5.5 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Fungal_trans_2 PF11951.3 OAP54814.1 - 8.4e-13 47.6 0.0 1.1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 OAP54815.1 - 6.3e-26 91.6 0.1 7.2e-26 91.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP54815.1 - 7.9e-22 77.9 0.4 9.4e-22 77.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP54815.1 - 7.5e-12 45.2 0.4 9.7e-12 44.9 0.3 1.1 1 0 0 1 1 1 1 KR domain MotA_activ PF09114.5 OAP54815.1 - 0.0005 19.7 1.2 0.0027 17.4 0.4 2.1 2 0 0 2 2 2 1 Transcription factor MotA, activation domain Epimerase PF01370.16 OAP54815.1 - 0.0055 16.1 0.1 0.0074 15.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dak1_2 PF13684.1 OAP54815.1 - 0.069 12.0 0.1 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Dihydroxyacetone kinase family DUF3407 PF11887.3 OAP54815.1 - 0.087 12.0 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) BON PF04972.12 OAP54815.1 - 0.12 12.1 0.2 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 BON domain DUF4231 PF14015.1 OAP54816.1 - 0.063 13.2 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PPR_3 PF13812.1 OAP54817.1 - 8e-12 44.4 1.1 0.0025 17.9 0.0 8.1 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 OAP54817.1 - 1.8e-06 27.8 0.0 7.4 6.6 0.0 6.2 6 1 1 7 7 7 3 PPR repeat family PPR PF01535.15 OAP54817.1 - 1.1e-05 25.0 0.0 5.6 7.1 0.0 5.4 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.1 OAP54817.1 - 0.15 12.7 7.9 8.4 7.3 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat CtnDOT_TraJ PF07863.6 OAP54818.1 - 0.044 14.2 0.4 0.063 13.7 0.3 1.2 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon E2R135 PF11570.3 OAP54818.1 - 0.075 13.1 0.1 0.094 12.8 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 WD40 PF00400.27 OAP54819.1 - 2.7e-48 160.1 30.3 1.3e-07 31.2 0.0 11.3 11 0 0 11 11 11 10 WD domain, G-beta repeat eIF2A PF08662.6 OAP54819.1 - 0.014 15.1 1.1 4.4 6.9 0.1 4.0 3 3 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 OAP54819.1 - 0.067 11.3 0.0 1.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) PD40 PF07676.7 OAP54819.1 - 0.12 12.1 0.6 37 4.1 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 OAP54819.1 - 0.45 9.3 3.0 2.5 6.9 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1513) SAGA-Tad1 PF12767.2 OAP54820.1 - 3.9e-50 170.8 0.0 5.3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Arginase PF00491.16 OAP54821.1 - 4.6e-83 278.7 0.0 5.9e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family Formyl_trans_N PF00551.14 OAP54822.1 - 1.4e-36 125.7 0.2 1.8e-36 125.4 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 OAP54822.1 - 1.7e-10 40.1 0.0 4.8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 OAP54822.1 - 6.2e-05 22.6 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain Ank_2 PF12796.2 OAP54823.1 - 1.5e-45 153.4 1.4 5e-13 49.1 0.1 8.7 5 3 2 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 OAP54823.1 - 2e-37 125.1 0.1 1.9e-07 30.5 0.0 10.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 OAP54823.1 - 2.5e-27 94.7 0.0 0.00015 22.1 0.0 9.3 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP54823.1 - 1.6e-26 89.7 0.1 0.0004 20.3 0.0 11.1 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.1 OAP54823.1 - 4.7e-25 87.0 0.9 0.0023 18.0 0.0 9.6 6 3 3 9 9 9 7 Ankyrin repeats (many copies) FbpA PF05833.6 OAP54824.1 - 1.5e-38 132.5 1.4 1.5e-38 132.5 0.9 2.4 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 OAP54824.1 - 1.2e-28 98.9 1.1 3.8e-28 97.3 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 OAP54824.1 - 4e-22 77.9 0.0 8.1e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Pneumo_att_G PF05539.6 OAP54824.1 - 4.7 6.4 9.6 8.1 5.7 6.6 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Clat_adaptor_s PF01217.15 OAP54825.1 - 1.1e-12 47.8 0.1 4.2e-12 45.9 0.2 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain FtsJ PF01728.14 OAP54826.1 - 4e-60 202.9 0.0 5.5e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 OAP54826.1 - 0.14 12.7 0.0 15 6.1 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain UCH PF00443.24 OAP54827.1 - 6e-55 186.2 0.0 9.6e-55 185.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAP54827.1 - 3.9e-24 85.6 0.0 7.3e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 OAP54827.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain VHS PF00790.14 OAP54828.1 - 3e-42 143.6 1.9 6.2e-41 139.3 0.1 2.5 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 OAP54828.1 - 1.2e-16 60.3 1.9 2.1e-16 59.5 1.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 OAP54828.1 - 1.3e-06 27.4 11.6 0.0018 17.6 1.1 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.9 OAP54828.1 - 0.0095 15.8 0.2 0.034 14.1 0.1 1.9 1 0 0 1 1 1 1 GAT domain C1_1 PF00130.17 OAP54828.1 - 0.028 14.1 2.6 0.062 13.0 1.8 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 OAP54828.1 - 0.042 13.7 0.5 0.092 12.6 0.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger HypA PF01155.14 OAP54828.1 - 0.26 11.0 1.5 0.54 9.9 1.0 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Sua5_yciO_yrdC PF01300.13 OAP54829.1 - 3.9e-53 179.3 0.0 7.2e-53 178.4 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 OAP54829.1 - 2.5e-15 56.6 0.0 5.4e-13 49.1 0.0 3.0 2 1 0 2 2 2 2 Putative GTP-binding controlling metal-binding MFS_1 PF07690.11 OAP54830.1 - 1.7e-27 96.0 34.2 1.6e-26 92.9 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.16 OAP54831.1 - 1.9e-85 287.4 0.0 4.2e-85 286.2 0.0 1.5 1 1 0 1 1 1 1 Amidase Pyridox_oxidase PF01243.15 OAP54833.1 - 1.9e-07 30.9 0.0 0.00019 21.3 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 OAP54833.1 - 1e-05 25.5 0.0 0.0029 17.6 0.0 3.0 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain HSP70 PF00012.15 OAP54835.1 - 2.7e-268 890.8 11.9 3.1e-268 890.6 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAP54835.1 - 1.2e-18 66.8 2.5 2.1e-17 62.7 0.7 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 OAP54835.1 - 0.0027 16.6 0.5 0.015 14.1 0.2 2.0 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 OAP54835.1 - 0.023 13.7 5.6 0.2 10.7 0.2 3.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 OAP54835.1 - 3.3 7.5 7.2 4 7.3 0.1 3.5 2 1 0 2 2 2 0 Cell division protein FtsA GST_N_3 PF13417.1 OAP54836.1 - 3e-25 88.2 0.0 5.1e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP54836.1 - 1.6e-18 66.4 0.0 2.6e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP54836.1 - 1.1e-08 34.8 0.1 2.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAP54836.1 - 3.1e-07 30.4 0.0 5.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP54836.1 - 0.00015 21.7 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP54836.1 - 0.0046 17.4 0.0 0.013 15.9 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2236 PF09995.4 OAP54836.1 - 0.084 12.1 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) F-actin_cap_A PF01267.12 OAP54837.1 - 7.7e-78 261.2 0.0 8.6e-78 261.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit GTP_EFTU PF00009.22 OAP54839.1 - 1.5e-50 171.2 0.0 2.7e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 OAP54839.1 - 3.3e-22 78.4 0.7 7.1e-22 77.3 0.5 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 OAP54839.1 - 4.8e-10 39.3 0.3 1.8e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 OAP54839.1 - 2.4e-09 37.2 0.0 1.3e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAP54839.1 - 1.5e-08 34.6 0.0 3.5e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 OAP54839.1 - 2.2e-05 24.9 0.1 0.0022 18.4 0.0 3.1 2 1 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 OAP54839.1 - 0.0032 16.6 0.0 0.0079 15.3 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 OAP54839.1 - 0.01 15.0 1.0 0.9 8.7 0.0 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 OAP54839.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 4 FeoB_N PF02421.13 OAP54839.1 - 0.016 14.4 0.2 0.41 9.9 0.1 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 OAP54839.1 - 0.075 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Septin Fructosamin_kin PF03881.9 OAP54843.1 - 7.9e-29 100.5 0.0 4.1e-20 71.9 0.0 2.1 1 1 1 2 2 2 2 Fructosamine kinase APH PF01636.18 OAP54843.1 - 0.00032 20.4 0.0 0.0076 16.0 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF466 PF04328.8 OAP54843.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF466) Zn_clus PF00172.13 OAP54844.1 - 1.1e-06 28.4 7.4 1.9e-06 27.6 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP54844.1 - 4.4e-06 25.7 2.2 1.1e-05 24.4 0.5 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 OAP54845.1 - 2.1e-59 201.3 0.0 2.5e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Nitroreductase PF00881.19 OAP54846.1 - 9.1e-12 45.1 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family GST_N_3 PF13417.1 OAP54847.1 - 2.4e-05 24.4 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP54847.1 - 5.9e-05 22.8 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAP54847.1 - 0.00061 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAP54847.1 - 0.0022 18.4 0.0 0.011 16.1 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ead_Ea22 PF13935.1 OAP54847.1 - 0.062 13.6 0.0 0.98 9.7 0.0 2.1 2 0 0 2 2 2 0 Ead/Ea22-like protein p450 PF00067.17 OAP54848.1 - 1.8e-59 201.4 0.0 2.4e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 OAP54849.1 - 1.3e-14 53.6 8.0 1.6e-14 53.4 5.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP54849.1 - 0.00019 20.1 0.2 0.0002 20.0 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3814 PF12769.2 OAP54849.1 - 0.39 10.9 3.1 0.11 12.6 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3814) MFS_1 PF07690.11 OAP54850.1 - 3.6e-15 55.5 0.3 4.1e-15 55.3 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 OAP54850.1 - 0.019 13.0 0.4 0.024 12.7 0.2 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector TRI12 PF06609.8 OAP54850.1 - 0.11 10.6 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) CBF PF03914.12 OAP54852.1 - 3.9e-42 143.4 0.3 7.2e-42 142.6 0.0 1.5 2 0 0 2 2 2 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.9 OAP54853.1 - 4.4e-53 179.0 6.7 5.5e-53 178.7 4.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 OAP54853.1 - 0.11 12.3 2.0 0.11 12.3 0.5 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Fib_alpha PF08702.5 OAP54853.1 - 6 6.9 8.4 50 4.0 5.8 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_11 PF13414.1 OAP54854.1 - 9.2e-19 66.8 33.6 0.00026 20.5 0.3 8.8 8 1 1 9 9 9 5 TPR repeat TPR_19 PF14559.1 OAP54854.1 - 8e-14 51.7 15.5 0.00018 21.7 0.0 6.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAP54854.1 - 7.6e-13 48.7 38.1 7.4e-05 23.3 0.1 8.1 8 1 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAP54854.1 - 4.7e-11 42.2 25.5 0.65 10.7 0.0 9.9 6 3 4 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 OAP54854.1 - 4.7e-07 29.4 7.6 0.94 9.8 0.0 8.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP54854.1 - 6.4e-07 28.8 36.1 0.38 10.7 0.1 11.1 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAP54854.1 - 1.1e-06 28.5 34.8 0.0094 15.8 0.2 7.3 7 1 2 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 OAP54854.1 - 2.4e-06 26.9 18.0 0.038 13.7 0.0 8.8 10 1 0 10 10 10 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAP54854.1 - 5.3e-05 22.9 8.0 0.00023 20.9 0.8 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAP54854.1 - 0.0055 16.5 0.5 2.6 7.9 0.0 4.0 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 OAP54854.1 - 0.014 14.9 27.9 1.4 8.6 0.0 9.0 11 0 0 11 11 10 0 Tetratricopeptide repeat Apc5 PF12862.2 OAP54854.1 - 0.034 13.9 0.1 0.2 11.4 0.0 2.4 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 5 TPR_20 PF14561.1 OAP54854.1 - 0.058 13.5 9.6 1.7 8.7 0.3 4.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP54854.1 - 0.18 12.2 20.6 19 5.9 0.2 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat ADH_N PF08240.7 OAP54855.1 - 1.3e-27 95.6 2.1 3.2e-27 94.4 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP54855.1 - 1.7e-18 66.3 0.2 3.2e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 OAP54855.1 - 0.00087 18.3 0.2 0.0014 17.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase ADH_zinc_N_2 PF13602.1 OAP54855.1 - 0.0027 18.5 0.0 0.0077 17.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAP54855.1 - 0.019 14.3 0.2 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 OAP54855.1 - 0.055 13.4 0.1 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.19 OAP54855.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 OAP54855.1 - 0.074 13.1 0.2 0.16 12.0 0.1 1.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDPD PF03009.12 OAP54856.1 - 4.3e-33 114.8 0.0 6.5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 OAP54856.1 - 0.015 15.5 1.1 0.048 13.8 0.8 1.9 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Amidase PF01425.16 OAP54857.1 - 1.9e-79 267.6 0.0 2.5e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Phage_G PF02306.10 OAP54857.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) Polysacc_deac_1 PF01522.16 OAP54858.1 - 5.7e-14 51.8 0.0 9e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Tubulin PF00091.20 OAP54859.1 - 1.3e-74 250.6 0.0 1.8e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAP54859.1 - 9.1e-46 154.9 0.6 1.5e-45 154.2 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAP54859.1 - 1.6e-07 31.3 0.0 4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain zf-AN1 PF01428.11 OAP54860.1 - 1.1e-10 41.2 6.5 1.6e-10 40.6 4.5 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.3 OAP54860.1 - 2.7e-09 36.6 0.0 3.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAP54860.1 - 5e-07 29.0 0.0 7.6e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Transp_Tc5_C PF04236.10 OAP54860.1 - 0.074 13.2 0.6 0.13 12.4 0.4 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Agouti PF05039.7 OAP54860.1 - 0.29 11.5 4.8 0.39 11.1 2.6 1.8 1 1 0 1 1 1 0 Agouti protein Pmp3 PF01679.12 OAP54862.1 - 2.3e-27 94.4 5.9 2.5e-27 94.3 4.1 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 OAP54862.1 - 0.064 12.9 2.7 0.064 12.9 1.8 1.8 2 0 0 2 2 2 0 Conserved TM helix Herpes_gE PF02480.11 OAP54863.1 - 0.13 10.5 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pcc1 PF09341.5 OAP54864.1 - 1.1e-21 76.6 0.0 1.3e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 OAP54865.1 - 5e-44 149.7 0.0 1.8e-40 138.1 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 OAP54865.1 - 2.1e-17 62.9 0.0 6.6e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAP54865.1 - 3.8e-06 26.4 0.0 8.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 OAP54865.1 - 0.0097 15.9 0.2 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 OAP54865.1 - 0.098 12.8 0.1 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 OAP54865.1 - 0.2 11.0 0.2 0.45 9.9 0.1 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Ribosomal_L22e PF01776.12 OAP54866.1 - 2.1e-49 166.1 0.1 2.5e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF3115 PF11312.3 OAP54867.1 - 9e-92 307.2 0.0 1.2e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) HCNGP PF07818.8 OAP54869.1 - 7e-28 96.5 0.0 1e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein RhoGAP PF00620.22 OAP54870.1 - 8.3e-40 135.8 0.1 1.9e-39 134.7 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 OAP54870.1 - 7.9e-12 45.3 0.0 1.6e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAP54870.1 - 2.9e-05 24.2 0.1 0.00019 21.6 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 OAP54870.1 - 0.00089 19.0 0.1 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 PX domain MFS_1 PF07690.11 OAP54871.1 - 4.4e-18 65.1 35.4 4.4e-18 65.1 24.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Iso_dh PF00180.15 OAP54872.1 - 4.1e-83 279.2 0.1 5e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NMO PF03060.10 OAP54873.1 - 2.7e-71 240.3 1.7 3.2e-71 240.1 1.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAP54873.1 - 5.1e-07 28.9 0.0 0.00018 20.5 0.0 2.4 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAP54873.1 - 0.0062 15.4 1.1 0.011 14.6 0.8 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TIM-br_sig_trns PF09370.5 OAP54873.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 TIM-barrel signal transduction protein PEP-utilizers PF00391.18 OAP54873.1 - 0.22 11.0 2.3 0.21 11.1 0.3 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain DNA_methylase PF00145.12 OAP54876.1 - 3.7e-07 29.5 0.0 4e-06 26.1 0.0 2.1 1 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase ABC_membrane PF00664.18 OAP54877.1 - 1.1e-53 182.4 37.6 1e-31 110.3 12.1 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 OAP54877.1 - 8.5e-49 165.3 0.0 1e-27 97.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAP54877.1 - 1.1e-07 32.1 0.1 0.13 12.1 0.0 4.0 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 OAP54877.1 - 4.6e-07 29.3 0.6 0.27 10.4 0.1 3.8 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 OAP54877.1 - 1.5e-06 28.6 0.3 0.077 13.4 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 OAP54877.1 - 2.8e-06 26.7 0.5 0.062 12.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 OAP54877.1 - 3.8e-06 26.8 0.0 0.017 15.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 OAP54877.1 - 8.1e-06 26.6 0.7 0.17 12.7 0.4 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAP54877.1 - 2.3e-05 24.4 2.1 0.084 12.8 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 OAP54877.1 - 0.00028 20.1 0.3 0.68 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 OAP54877.1 - 0.00029 19.9 0.0 0.089 11.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 OAP54877.1 - 0.0007 19.7 0.2 1.8 8.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAP54877.1 - 0.0034 16.8 0.1 1.8 7.9 0.1 2.6 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 OAP54877.1 - 0.0039 17.4 0.2 0.88 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAP54877.1 - 0.005 16.2 0.1 2.3 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 OAP54877.1 - 0.008 16.0 1.9 0.21 11.3 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_15 PF13175.1 OAP54877.1 - 0.016 14.2 0.0 2 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 OAP54877.1 - 0.025 14.2 1.4 2.4 7.8 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 OAP54877.1 - 0.03 14.6 11.2 0.37 11.0 0.0 3.4 2 1 1 3 3 2 0 AAA domain NACHT PF05729.7 OAP54877.1 - 0.03 13.9 0.4 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 OAP54877.1 - 0.041 12.7 0.1 0.49 9.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 OAP54877.1 - 0.045 13.5 6.5 0.39 10.5 0.1 3.2 3 0 0 3 3 3 0 Dynamin family PduV-EutP PF10662.4 OAP54877.1 - 0.047 13.1 0.5 1.8 8.0 0.1 3.2 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 OAP54877.1 - 0.066 12.7 0.5 8.2 5.8 0.1 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 OAP54877.1 - 0.18 11.2 1.4 1 8.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 OAP54877.1 - 0.28 11.1 0.0 0.28 11.1 0.0 3.0 4 0 0 4 4 2 0 AAA domain BLVR PF06375.6 OAP54877.1 - 0.95 9.2 11.9 0.27 11.0 1.9 2.5 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DMAP1 PF05499.7 OAP54877.1 - 1.1 8.8 10.2 0.12 11.9 0.7 2.5 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) adh_short PF00106.20 OAP54878.1 - 7.9e-22 77.9 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54878.1 - 7.2e-16 58.6 0.0 9e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54878.1 - 1.1e-05 25.2 0.0 1.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP54878.1 - 3.8e-05 23.7 0.0 9.1e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Vitellogenin_N PF01347.17 OAP54878.1 - 0.0057 14.9 0.0 0.0074 14.5 0.0 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region Epimerase PF01370.16 OAP54878.1 - 0.045 13.1 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fer2_3 PF13085.1 OAP54879.1 - 3.3e-31 107.3 0.0 5.2e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 OAP54879.1 - 2e-09 37.6 6.2 2e-09 37.6 4.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAP54879.1 - 3.5e-09 36.5 4.3 3.5e-09 36.5 3.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 OAP54879.1 - 0.00011 22.5 1.2 0.00011 22.5 0.8 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAP54879.1 - 0.00026 20.6 4.2 0.00026 20.6 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAP54879.1 - 0.00076 19.6 4.3 0.045 14.0 0.6 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 OAP54879.1 - 0.0024 18.1 3.9 0.0024 18.1 2.7 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 OAP54879.1 - 0.0082 15.8 0.3 0.0082 15.8 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 OAP54879.1 - 0.7 10.4 4.7 1.3 9.6 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain AIG2_2 PF13772.1 OAP54880.1 - 8.2e-07 29.0 0.0 2.4e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 AIG2-like family GATase_4 PF13230.1 OAP54882.1 - 1.8e-12 46.5 0.0 2.2e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAP54882.1 - 6.8e-09 35.7 0.1 1.1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAP54882.1 - 6.3e-07 28.4 0.6 9.4e-07 27.8 0.4 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HTH_35 PF13693.1 OAP54882.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GATase_7 PF13537.1 OAP54882.1 - 0.041 13.6 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain ABC_tran PF00005.22 OAP54883.1 - 4.2e-31 108.0 0.1 9.8e-18 64.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 OAP54883.1 - 6e-27 94.7 26.5 2.9e-21 76.1 6.8 2.9 3 1 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 OAP54883.1 - 2.9e-07 30.7 0.0 0.00072 19.6 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAP54883.1 - 9.8e-06 25.6 0.2 0.011 15.7 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain DUF1286 PF06939.6 OAP54883.1 - 0.00037 20.6 0.2 0.00037 20.6 0.1 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1286) AAA_22 PF13401.1 OAP54883.1 - 0.00087 19.4 0.0 0.023 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAP54883.1 - 0.00089 18.7 0.0 0.34 10.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 OAP54883.1 - 0.014 14.3 0.0 0.29 9.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DnaB_C PF03796.10 OAP54883.1 - 0.018 13.9 0.1 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_15 PF13175.1 OAP54883.1 - 0.028 13.4 0.1 0.099 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 OAP54883.1 - 0.029 13.9 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 OAP54883.1 - 0.04 12.9 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 OAP54883.1 - 0.041 13.3 0.1 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 OAP54883.1 - 0.054 14.3 0.0 0.19 12.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 OAP54883.1 - 0.068 13.3 0.0 7.8 6.6 0.0 3.0 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 OAP54883.1 - 0.082 12.5 0.0 7.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 OAP54883.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 OAP54883.1 - 0.59 10.4 1.7 0.61 10.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Glyco_hydro_47 PF01532.15 OAP54884.1 - 2.6e-164 547.2 1.7 3.2e-164 546.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WBS_methylT PF12589.3 OAP54885.1 - 3.8e-14 52.9 5.8 6e-14 52.3 4.0 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 OAP54885.1 - 6.5e-11 42.5 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP54885.1 - 2.6e-07 30.9 0.0 6.3e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP54885.1 - 2.7e-06 27.9 0.1 1.1e-05 25.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP54885.1 - 9.4e-06 26.0 0.0 2.3e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP54885.1 - 2.1e-05 24.1 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP54885.1 - 2.8e-05 23.8 0.0 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP54885.1 - 3.1e-05 23.9 0.0 6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAP54885.1 - 0.00033 20.2 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.8 OAP54885.1 - 0.0095 16.0 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Ubie_methyltran PF01209.13 OAP54885.1 - 0.0095 15.0 0.2 0.036 13.1 0.0 2.0 2 1 0 3 3 3 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 OAP54885.1 - 0.061 12.3 0.0 0.091 11.8 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase AA_permease_2 PF13520.1 OAP54886.1 - 6.9e-57 192.8 52.1 8.4e-57 192.6 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP54886.1 - 6e-27 94.1 42.8 6e-27 94.1 29.7 1.9 1 1 1 2 2 2 1 Amino acid permease Phage_CII PF05269.6 OAP54886.1 - 0.04 13.9 1.2 0.1 12.6 0.0 2.3 2 1 1 3 3 3 0 Bacteriophage CII protein Erv26 PF04148.8 OAP54887.1 - 3.8e-84 281.2 0.0 4.3e-84 281.1 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 TENA_THI-4 PF03070.11 OAP54888.1 - 9.4e-14 51.6 0.0 1.1e-12 48.2 0.0 2.3 1 1 0 1 1 1 1 TENA/THI-4/PQQC family adh_short PF00106.20 OAP54889.1 - 3.7e-25 88.7 0.0 6e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54889.1 - 2.9e-14 53.4 0.0 4.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54889.1 - 1.1e-05 25.1 0.0 2.4e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP54889.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP54889.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding zf-H2C2_2 PF13465.1 OAP54890.1 - 3.3e-15 55.5 17.0 1.4e-07 31.4 1.6 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 OAP54890.1 - 2.8e-10 39.9 23.3 0.01 16.1 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP54890.1 - 4.9e-08 32.7 21.2 0.0082 16.4 4.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 OAP54890.1 - 0.0042 17.1 10.9 0.011 15.8 4.5 2.3 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 OAP54890.1 - 0.0053 17.3 0.9 0.16 12.5 0.1 2.7 1 1 1 2 2 2 1 Protein of unknown function (FYDLN_acid) zf-C2HC_2 PF13913.1 OAP54890.1 - 0.0071 15.9 0.8 0.0071 15.9 0.5 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 OAP54890.1 - 0.018 15.1 8.6 0.49 10.5 1.9 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 OAP54890.1 - 0.049 13.4 4.4 5.7 6.8 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_6 PF13912.1 OAP54890.1 - 0.054 13.4 12.3 0.23 11.4 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1192 PF06698.6 OAP54890.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) zf-RING_3 PF14369.1 OAP54890.1 - 0.16 12.0 3.4 17 5.4 0.1 3.4 3 0 0 3 3 3 0 zinc-finger DZR PF12773.2 OAP54890.1 - 0.16 11.8 5.6 2.8 7.8 3.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon bZIP_2 PF07716.10 OAP54890.1 - 0.19 11.5 1.7 0.33 10.7 1.2 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Zn-ribbon_8 PF09723.5 OAP54890.1 - 0.19 11.7 8.4 2.4 8.1 1.9 3.0 1 1 1 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 OAP54890.1 - 0.35 10.7 8.4 2.1 8.2 2.6 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 OAP54890.1 - 0.41 10.8 6.4 0.77 9.9 4.4 1.4 1 0 0 1 1 1 0 CHY zinc finger THOC7 PF05615.8 OAP54890.1 - 0.42 10.8 3.2 0.64 10.2 2.2 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 DUF3450 PF11932.3 OAP54890.1 - 0.54 9.4 5.7 0.78 8.9 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-C3HC4_3 PF13920.1 OAP54890.1 - 0.67 9.6 4.4 4.7 6.9 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 OAP54890.1 - 1.4 8.4 4.4 6.7 6.3 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 OAP54890.1 - 5.8 7.0 10.6 2.7 8.1 1.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Aminotran_5 PF00266.14 OAP54891.1 - 1.5e-22 79.9 0.0 2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.12 OAP54891.1 - 7.6e-21 73.9 0.1 1.5e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 OAP54891.1 - 2.3e-19 69.2 0.0 4.9e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Sugar_tr PF00083.19 OAP54892.1 - 1.6e-69 234.6 25.2 2.8e-69 233.8 17.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP54892.1 - 2.6e-15 56.0 29.6 5.7e-11 41.7 13.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP54892.1 - 4.7e-07 28.5 0.4 4.7e-07 28.5 0.3 3.0 3 1 0 3 3 3 1 MFS/sugar transport protein MARVEL PF01284.18 OAP54893.1 - 5e-07 29.6 16.1 6.7e-07 29.2 11.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain UNC-50 PF05216.8 OAP54893.1 - 0.31 10.2 5.8 0.041 13.0 1.2 1.5 2 0 0 2 2 2 0 UNC-50 family PLDc_N PF13396.1 OAP54893.1 - 6.1 6.6 10.7 0.17 11.5 0.4 3.1 3 1 0 3 3 3 0 Phospholipase_D-nuclease N-terminal Longin PF13774.1 OAP54895.1 - 0.12 11.9 0.0 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 Regulated-SNARE-like domain ADH_N PF08240.7 OAP54896.1 - 1.3e-24 86.0 2.3 1.3e-24 86.0 1.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP54896.1 - 8.4e-17 60.9 1.4 1.2e-16 60.3 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP54896.1 - 0.00069 20.5 0.2 0.0012 19.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.4 OAP54896.1 - 0.23 10.6 1.5 0.38 9.9 0.2 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region CHCH PF06747.8 OAP54899.1 - 0.00016 21.4 7.2 0.00027 20.7 5.0 1.4 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 OAP54899.1 - 0.00036 20.6 1.9 0.00053 20.1 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) PSRP-3_Ycf65 PF04839.8 OAP54899.1 - 0.066 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Ca_chan_IQ PF08763.6 OAP54899.1 - 0.16 11.2 1.4 0.25 10.6 0.3 1.9 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain UPF0203 PF05254.7 OAP54899.1 - 0.19 11.5 5.6 0.64 9.9 3.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 OAP54899.1 - 0.27 11.0 5.7 0.35 10.6 0.8 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NatB_MDM20 PF09797.4 OAP54900.1 - 3e-37 128.1 0.0 7e-37 126.9 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 OAP54900.1 - 0.18 12.1 0.1 0.18 12.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4363 PF14276.1 OAP54900.1 - 0.18 11.4 6.3 10 5.8 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Ipi1_N PF12333.3 OAP54900.1 - 1.8 8.5 6.3 7.8 6.5 0.1 3.3 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Proteasome PF00227.21 OAP54901.1 - 4.9e-41 140.0 0.0 5.7e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit H_lectin PF09458.5 OAP54901.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 H-type lectin domain TUG-UBL1 PF11470.3 OAP54902.1 - 3.7e-25 87.6 0.0 8.8e-25 86.4 0.0 1.7 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 OAP54902.1 - 1.9e-05 24.6 0.2 0.0001 22.2 0.0 2.4 3 0 0 3 3 3 1 UBX domain Ribosomal_L38e PF01781.13 OAP54903.1 - 1.4e-29 101.6 3.1 1.8e-29 101.3 2.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Acetyltransf_3 PF13302.1 OAP54904.1 - 4.2e-14 52.8 0.0 6.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP54904.1 - 3e-05 23.6 0.1 0.028 14.1 0.1 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.19 OAP54904.1 - 0.001 19.0 0.1 0.054 13.5 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DNA_pol_E_B PF04042.11 OAP54905.1 - 1.1e-44 152.1 0.0 1.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B 4HBT PF03061.17 OAP54907.1 - 3.1e-11 43.2 0.4 6.2e-11 42.2 0.3 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 OAP54907.1 - 0.00055 19.9 0.0 0.00073 19.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 OAP54907.1 - 0.0067 16.1 2.0 0.0074 16.0 1.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.14 OAP54907.1 - 0.05 12.9 0.1 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain 4HBT_2 PF13279.1 OAP54907.1 - 0.094 13.1 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Thioesterase-like superfamily Glyco_transf_25 PF01755.12 OAP54908.1 - 1.9e-10 40.7 1.5 3.4e-08 33.3 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF1777 PF08648.7 OAP54908.1 - 4.6 6.9 34.3 8.2 6.1 23.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CAP59_mtransfer PF11735.3 OAP54909.1 - 6.9e-55 185.8 0.0 9.1e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glycos_transf_2 PF00535.21 OAP54909.1 - 0.0046 16.6 0.3 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 G-patch PF01585.18 OAP54910.1 - 1.6e-05 24.5 1.2 0.00016 21.3 0.1 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 OAP54910.1 - 0.051 13.4 0.2 0.051 13.4 0.1 4.2 3 2 1 4 4 4 0 DExH-box splicing factor binding site TFIIF_alpha PF05793.7 OAP54910.1 - 0.076 11.3 20.2 0.1 10.9 14.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PLRV_ORF5 PF01690.12 OAP54910.1 - 0.34 9.9 12.6 0.5 9.4 8.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CDC27 PF09507.5 OAP54910.1 - 0.68 9.0 23.7 1.1 8.4 16.5 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mannosyl_trans3 PF11051.3 OAP54911.1 - 4.9e-38 131.0 0.0 6.3e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative DUF3589 PF12141.3 OAP54912.1 - 2.4e-82 276.7 0.0 3.6e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) Acyl_transf_3 PF01757.17 OAP54913.1 - 3.1e-22 78.8 12.2 5.9e-22 77.9 8.4 1.5 1 1 0 1 1 1 1 Acyltransferase family Pkinase PF00069.20 OAP54914.1 - 9e-77 257.7 0.0 1.4e-76 257.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP54914.1 - 4.9e-38 130.6 0.0 7.2e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 OAP54914.1 - 3.3e-17 62.3 0.1 9.3e-17 60.9 0.0 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 OAP54914.1 - 1.8e-09 37.0 0.0 6.1e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 OAP54914.1 - 0.013 14.2 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 OAP54914.1 - 0.061 13.0 0.0 0.2 11.3 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 OAP54914.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GRA6 PF05084.8 OAP54915.1 - 2.6 7.5 12.9 4.8 6.6 8.9 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Glyco_transf_25 PF01755.12 OAP54916.1 - 1.4e-07 31.3 0.0 1.9e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_transf_34 PF05637.7 OAP54917.1 - 2e-11 43.8 0.0 1.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family TPT PF03151.11 OAP54918.1 - 5.7e-17 61.7 4.7 5.7e-17 61.7 3.3 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 OAP54918.1 - 1.7e-06 28.0 25.1 2e-06 27.8 4.3 2.8 2 2 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 OAP54918.1 - 6 7.0 24.9 0.065 13.4 5.0 2.9 1 1 2 3 3 3 0 Multidrug resistance efflux transporter Hid1 PF12722.2 OAP54919.1 - 0.042 11.5 0.6 0.058 11.0 0.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ank_2 PF12796.2 OAP54920.1 - 2e-55 185.0 5.3 3e-20 72.3 0.1 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 OAP54920.1 - 5.7e-38 126.8 1.6 1.1e-09 37.5 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 OAP54920.1 - 1.6e-26 91.7 2.0 3.6e-07 30.2 0.1 5.7 2 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP54920.1 - 2.1e-26 91.7 0.5 5.2e-07 30.0 0.0 5.9 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP54920.1 - 1.9e-24 83.2 0.8 4.4e-06 26.4 0.0 7.7 7 0 0 7 7 7 3 Ankyrin repeat CorA PF01544.13 OAP54920.1 - 4.7e-07 29.1 2.6 0.00018 20.6 0.0 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein PI3_PI4_kinase PF00454.22 OAP54921.1 - 7.6e-38 130.2 0.0 4e-37 127.9 0.0 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 OAP54921.1 - 2e-24 85.8 0.1 5e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RAMP4 PF06624.7 OAP54922.1 - 5e-07 29.1 0.0 5.8e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Herpes_US9 PF06072.6 OAP54922.1 - 0.092 12.5 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ADIP PF11559.3 OAP54923.1 - 0.0065 16.3 7.9 0.0065 16.3 5.5 3.7 3 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.6 OAP54923.1 - 0.016 15.5 3.4 0.016 15.5 2.4 3.9 1 1 3 4 4 4 0 Syntaxin 6, N-terminal bZIP_2 PF07716.10 OAP54923.1 - 0.017 14.9 7.4 0.017 14.9 5.1 4.2 2 2 2 4 4 4 0 Basic region leucine zipper Filament PF00038.16 OAP54923.1 - 0.036 13.5 36.3 0.024 14.0 23.4 1.9 1 1 0 1 1 1 0 Intermediate filament protein GAS PF13851.1 OAP54923.1 - 0.13 11.3 42.3 0.42 9.7 2.4 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 OAP54923.1 - 0.14 9.4 32.0 0.21 8.9 22.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 OAP54923.1 - 0.38 8.5 22.6 0.52 8.1 15.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.4 OAP54923.1 - 1.5 8.5 36.3 0.15 11.8 7.1 2.6 1 1 0 2 2 2 0 Axonemal dynein light chain AAA_13 PF13166.1 OAP54923.1 - 1.6 7.0 30.9 18 3.5 21.4 2.0 1 1 0 1 1 1 0 AAA domain DUF4045 PF13254.1 OAP54923.1 - 2.7 7.1 14.9 4.2 6.5 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MmgE_PrpD PF03972.9 OAP54924.1 - 7.2e-73 245.2 6.6 8.8e-73 244.9 4.6 1.0 1 0 0 1 1 1 1 MmgE/PrpD family adh_short_C2 PF13561.1 OAP54925.1 - 1.6e-23 83.7 0.0 1.9e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP54925.1 - 1e-21 77.5 0.3 1.4e-21 77.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP54925.1 - 0.0031 17.1 0.2 0.0067 16.1 0.1 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP54925.1 - 0.19 11.5 1.6 0.52 10.1 1.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sulfatase PF00884.18 OAP54926.1 - 9.5e-46 156.3 0.1 6.2e-45 153.7 0.1 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 OAP54926.1 - 4.4e-10 39.4 0.9 1.5e-09 37.6 0.6 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 OAP54926.1 - 0.0032 17.7 0.0 0.0066 16.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 OAP54926.1 - 0.01 14.7 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.12 OAP54926.1 - 0.1 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.19 OAP54927.1 - 2.1e-79 267.2 19.5 2.4e-79 267.0 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP54927.1 - 7.3e-12 44.6 25.6 7.9e-06 24.8 3.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.18 OAP54928.1 - 7e-69 232.3 0.0 8.4e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 OAP54928.1 - 0.00051 18.5 0.0 0.0007 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 OAP54928.1 - 0.00052 19.4 0.0 0.63 9.2 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 OAP54928.1 - 0.25 11.6 0.7 2.9 8.2 0.5 2.2 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Fungal_trans PF04082.13 OAP54929.1 - 3.7e-12 45.6 0.3 5.7e-12 45.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 OAP54930.1 - 3.3e-75 245.5 16.2 6.2e-10 38.5 0.1 11.9 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 OAP54930.1 - 2.1e-41 140.8 0.0 4e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 OAP54930.1 - 1.1e-08 33.6 7.2 0.00098 17.3 0.4 5.1 4 1 0 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 OAP54930.1 - 0.024 12.9 0.0 0.054 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain G-patch_2 PF12656.2 OAP54931.1 - 3e-21 75.0 0.3 3e-21 75.0 0.2 2.5 3 0 0 3 3 3 1 DExH-box splicing factor binding site zf-RING_2 PF13639.1 OAP54932.1 - 5.7e-09 35.6 5.7 5.7e-09 35.6 3.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP54932.1 - 4.6e-08 32.9 6.9 4.6e-08 32.9 4.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP54932.1 - 5.3e-08 32.3 5.6 5.3e-08 32.3 3.9 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP54932.1 - 7.2e-08 31.9 4.4 7.2e-08 31.9 3.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP54932.1 - 5.6e-07 29.1 6.0 5.6e-07 29.1 4.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAP54932.1 - 1.4e-06 28.0 6.3 1.4e-06 28.0 4.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAP54932.1 - 4.1e-05 23.2 2.2 0.0001 21.9 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger CpXC PF14353.1 OAP54932.1 - 0.042 13.8 0.4 0.38 10.7 0.0 2.4 1 1 0 2 2 2 0 CpXC protein DZR PF12773.2 OAP54932.1 - 0.17 11.7 9.4 3.8 7.3 2.4 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-4CXXC_R1 PF10497.4 OAP54932.1 - 0.51 10.4 5.7 0.12 12.5 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Proteasome PF00227.21 OAP54933.1 - 7.8e-30 103.5 0.0 8.8e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 OAP54934.1 - 3e-27 93.4 10.1 7.4e-08 31.9 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAP54934.1 - 0.02 13.6 0.0 0.79 8.3 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 OAP54934.1 - 0.11 10.6 0.0 3.7 5.5 0.0 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Abhydrolase_6 PF12697.2 OAP54936.1 - 2.7e-27 96.1 4.2 3.2e-27 95.9 2.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP54936.1 - 3.1e-16 59.4 0.2 5.6e-16 58.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP54936.1 - 1.2e-08 34.8 0.0 1e-07 31.7 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAP54936.1 - 3.5e-05 23.5 0.1 6.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 OAP54936.1 - 0.00043 19.7 0.1 0.00064 19.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 OAP54936.1 - 0.00083 18.3 0.4 0.002 17.0 0.3 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme UPF0227 PF05728.7 OAP54936.1 - 0.00094 18.9 0.1 0.0027 17.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 OAP54936.1 - 0.0013 19.0 0.1 0.0023 18.1 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.6 OAP54936.1 - 0.002 17.0 0.9 0.0043 15.9 0.6 1.4 1 1 0 1 1 1 1 Chlorophyllase Esterase PF00756.15 OAP54936.1 - 0.013 14.8 0.0 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 Putative esterase SAM_2 PF07647.12 OAP54937.1 - 1.2e-09 37.8 0.0 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAP54937.1 - 1.6e-07 31.4 0.1 4.1e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 OAP54937.1 - 4e-06 26.9 0.1 7.9e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 PH domain HTH_32 PF13565.1 OAP54937.1 - 0.051 14.3 1.4 0.24 12.1 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Fungal_trans_2 PF11951.3 OAP54938.1 - 3e-69 233.4 0.5 3.9e-69 233.1 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP54938.1 - 1.2e-07 31.5 10.1 2.2e-07 30.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 OAP54940.1 - 8.1e-24 84.7 0.1 1.1e-23 84.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP54940.1 - 4.9e-12 45.8 0.0 1.9e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP54940.1 - 2.1e-09 37.3 0.0 6.5e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 OAP54940.1 - 1.3e-05 24.5 0.0 0.022 14.0 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 OAP54940.1 - 2e-05 24.3 0.0 5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 OAP54940.1 - 0.0032 16.9 0.1 0.065 12.6 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF676 PF05057.9 OAP54940.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2048 PF09752.4 OAP54940.1 - 0.046 12.6 0.0 0.33 9.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_3 PF07859.8 OAP54940.1 - 0.047 13.2 0.0 0.095 12.2 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold WD40 PF00400.27 OAP54941.1 - 4.8e-09 35.7 0.7 2.3e-05 24.1 0.4 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat TFIIF_alpha PF05793.7 OAP54941.1 - 0.69 8.2 9.0 0.97 7.7 6.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MFS_1 PF07690.11 OAP54942.1 - 1.2e-31 109.7 73.3 4.1e-30 104.6 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fe-ADH PF00465.14 OAP54943.1 - 6.2e-73 245.5 0.8 7e-73 245.3 0.6 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAP54943.1 - 2.2e-16 59.9 0.2 2.9e-16 59.5 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fungal_trans_2 PF11951.3 OAP54944.1 - 0.0029 16.2 2.8 0.25 9.8 0.4 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain TerC PF03741.11 OAP54944.1 - 0.01 15.2 0.5 0.22 10.9 0.1 2.0 1 1 1 2 2 2 0 Integral membrane protein TerC family DUF4064 PF13273.1 OAP54944.1 - 0.063 13.3 0.2 1.1 9.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ILVD_EDD PF00920.16 OAP54944.1 - 0.084 11.2 0.2 0.098 11.0 0.1 1.0 1 0 0 1 1 1 0 Dehydratase family Mlo PF03094.10 OAP54944.1 - 0.095 10.7 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Mlo family DUF2644 PF10841.3 OAP54944.1 - 0.13 12.3 1.3 14 5.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) Diphthamide_syn PF01866.12 OAP54945.1 - 3.3e-52 177.6 0.0 2.8e-51 174.5 0.0 2.1 1 1 0 1 1 1 1 Putative diphthamide synthesis protein ComA PF02679.10 OAP54946.1 - 2.8e-83 278.6 0.0 3.3e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) AP_endonuc_2 PF01261.19 OAP54946.1 - 0.092 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Oxidored_FMN PF00724.15 OAP54946.1 - 0.14 11.1 0.0 0.54 9.1 0.0 1.7 2 0 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family PLA2_B PF01735.13 OAP54947.1 - 7.8e-194 644.4 0.6 9.2e-194 644.1 0.4 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MFS_1 PF07690.11 OAP54948.1 - 5.5e-42 143.7 31.9 5.5e-42 143.7 22.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP54948.1 - 1.7e-09 36.4 4.9 3.5e-09 35.4 3.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAP54948.1 - 0.00024 19.8 13.0 0.00024 19.8 9.0 2.6 2 2 0 2 2 2 2 Sugar (and other) transporter ATP-synt_B PF00430.13 OAP54948.1 - 0.027 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Ribophorin_II PF05817.9 OAP54949.1 - 8e-22 77.2 3.5 2.7e-21 75.4 2.4 1.7 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4124 PF13511.1 OAP54949.1 - 0.26 11.3 1.4 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Ytp1 PF10355.4 OAP54950.1 - 9.5e-66 221.7 7.3 1.1e-65 221.5 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF3481 PF11980.3 OAP54950.1 - 0.018 14.8 0.4 0.14 12.0 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3481) Ferric_reduct PF01794.14 OAP54950.1 - 0.035 14.1 1.2 0.073 13.1 0.8 1.5 1 0 0 1 1 1 0 Ferric reductase like transmembrane component EOS1 PF12326.3 OAP54950.1 - 0.069 12.7 0.4 0.069 12.7 0.3 2.0 1 1 1 2 2 2 0 N-glycosylation protein SLAC1 PF03595.12 OAP54950.1 - 0.4 9.2 8.5 1.2 7.6 0.4 2.1 1 1 1 2 2 2 0 Voltage-dependent anion channel UPF0114 PF03350.11 OAP54950.1 - 2.3 8.1 6.0 11 5.9 1.2 2.8 3 0 0 3 3 3 0 Uncharacterized protein family, UPF0114 DUF202 PF02656.10 OAP54950.1 - 3.9 7.7 6.6 2.5 8.4 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Rcd1 PF04078.8 OAP54951.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Abhydrolase_5 PF12695.2 OAP54952.1 - 3.3e-09 36.6 0.0 1.5e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP54952.1 - 1e-08 35.3 0.1 2.6e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAP54952.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 OAP54952.1 - 0.0017 17.9 0.0 0.043 13.3 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.6 OAP54952.1 - 0.021 13.3 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.15 OAP54952.1 - 0.024 14.1 0.0 0.14 11.6 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP54952.1 - 0.041 13.0 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3593 PF12159.3 OAP54952.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) 7TM_GPCR_Srh PF10318.4 OAP54955.1 - 0.0013 17.6 3.0 0.0015 17.3 1.4 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh DUF1516 PF07457.6 OAP54955.1 - 0.021 14.9 0.5 0.021 14.9 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) NfeD PF01957.13 OAP54955.1 - 1.2 9.2 9.2 0.1 12.7 1.5 2.4 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding MARVEL PF01284.18 OAP54955.1 - 1.4 8.7 11.1 3 7.6 7.5 1.9 1 1 0 1 1 1 0 Membrane-associating domain DUF4231 PF14015.1 OAP54955.1 - 2 8.4 6.2 0.3 11.1 0.7 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Claudin_2 PF13903.1 OAP54955.1 - 2.6 7.6 15.5 59 3.2 10.8 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Herpes_gE PF02480.11 OAP54955.1 - 6.2 4.9 7.0 8.6 4.4 0.2 2.7 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E Pyr_redox_3 PF13738.1 OAP54956.1 - 7.5e-22 78.3 0.0 1.1e-21 77.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP54956.1 - 6.3e-14 51.0 0.4 6.1e-13 47.8 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP54956.1 - 7.3e-12 44.8 0.2 2.8e-10 39.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP54956.1 - 8.2e-12 44.9 0.0 2.4e-10 40.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP54956.1 - 1.7e-07 31.3 0.0 8.8e-06 25.7 0.0 2.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP54956.1 - 5.2e-06 25.5 1.3 0.00083 18.3 0.0 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP54956.1 - 0.00021 21.0 0.2 0.23 11.1 0.2 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAP54956.1 - 0.00052 19.1 0.6 0.0012 17.9 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 OAP54956.1 - 0.0011 17.9 0.0 0.0075 15.2 0.0 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 OAP54956.1 - 0.0019 18.5 0.1 1.1 9.7 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP54956.1 - 0.019 13.8 0.0 0.048 12.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 OAP54956.1 - 0.052 12.0 0.3 0.18 10.2 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Enkurin PF13864.1 OAP54956.1 - 0.072 13.3 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Calmodulin-binding GATase PF00117.23 OAP54957.1 - 1.4e-06 27.8 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 OAP54957.1 - 0.0039 16.8 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family MFS_1 PF07690.11 OAP54958.1 - 3.3e-24 85.2 23.1 3.3e-24 85.2 16.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP54958.1 - 7.8e-10 37.9 10.9 7.8e-10 37.9 7.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Methyltransf_29 PF03141.11 OAP54958.1 - 0.16 10.2 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Flavoprotein PF02441.14 OAP54959.1 - 8.4e-27 93.3 0.1 1.1e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Fungal_trans PF04082.13 OAP54960.1 - 4.4e-30 104.4 0.1 8e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Complex1_LYR PF05347.10 OAP54960.1 - 0.014 15.1 0.1 0.044 13.5 0.1 1.9 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Zn_clus PF00172.13 OAP54960.1 - 0.028 14.3 0.3 0.057 13.3 0.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UbiD PF01977.11 OAP54961.1 - 2e-113 378.9 0.0 2.3e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Abhydrolase_6 PF12697.2 OAP54962.1 - 1.4e-19 70.9 0.3 1.9e-19 70.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP54962.1 - 3.7e-08 33.2 0.0 5.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP54962.1 - 1.6e-06 27.8 0.0 2.1e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF4175 PF13779.1 OAP54963.1 - 1 6.9 14.8 0.95 7.0 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) adh_short PF00106.20 OAP54964.1 - 7.2e-10 39.0 0.0 1.7e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP54964.1 - 0.0041 16.8 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Alpha-amylase_N PF02903.9 OAP54964.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain YfkD PF14167.1 OAP54964.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 YfkD-like protein Abhydrolase_3 PF07859.8 OAP54965.1 - 4.1e-54 183.3 0.0 5.2e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP54965.1 - 2.1e-14 53.1 1.1 5.2e-14 51.8 0.8 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 OAP54965.1 - 1.5e-06 27.6 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP54965.1 - 0.00029 20.5 0.2 0.00045 20.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP54965.1 - 0.00055 19.8 1.2 0.0016 18.3 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 OAP54965.1 - 0.019 14.2 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 OAP54965.1 - 0.023 14.2 0.0 0.058 12.9 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2424 PF10340.4 OAP54965.1 - 0.047 12.3 0.0 0.076 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) adh_short PF00106.20 OAP54966.1 - 5.2e-17 62.2 0.0 6.7e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP54966.1 - 5.3e-08 32.9 0.0 6.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP54966.1 - 1.6e-06 27.9 0.0 1.3e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 KR domain 4HBT_3 PF13622.1 OAP54968.1 - 2.9e-26 92.7 4.7 4.1e-26 92.2 3.3 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAP54968.1 - 1.2e-13 50.8 0.9 6.6e-10 38.7 0.6 3.3 2 2 1 3 3 3 2 Acyl-CoA thioesterase Phenol_monoox PF04663.7 OAP54968.1 - 0.024 14.3 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Phenol hydroxylase conserved region ATP_bind_4 PF01902.12 OAP54969.1 - 9.3e-16 57.8 0.0 8.5e-06 25.2 0.0 4.1 3 1 0 3 3 3 3 ATP-binding region Ribonuc_L-PSP PF01042.16 OAP54969.1 - 2.2e-12 46.7 0.0 9.6e-07 28.5 0.0 3.6 3 1 0 3 3 3 2 Endoribonuclease L-PSP zf-C2H2 PF00096.21 OAP54970.1 - 4.7e-12 45.5 12.1 2.5e-06 27.5 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP54970.1 - 4.3e-10 39.2 10.7 0.00027 21.0 3.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP54970.1 - 4.1e-07 29.9 12.2 3e-06 27.2 3.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAP54970.1 - 4.3e-05 23.5 9.4 0.0024 17.9 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP54970.1 - 0.0014 18.7 9.1 0.0034 17.5 0.3 2.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 OAP54970.1 - 0.017 15.0 9.3 0.02 14.7 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 OAP54970.1 - 3 7.6 7.0 2.5 7.9 2.2 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 OAP54970.1 - 6.2 6.9 9.1 5.7 7.1 0.2 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) PITH PF06201.8 OAP54971.1 - 5.2e-45 152.9 0.1 8.1e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 OAP54971.1 - 6e-27 93.3 0.0 1.1e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAP54971.1 - 1.1e-06 28.7 0.0 2.1e-05 24.5 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 OAP54971.1 - 1.1e-05 25.5 0.1 5e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 OAP54971.1 - 0.0016 18.0 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 OAP54971.1 - 0.004 16.8 0.1 0.78 9.4 0.0 2.3 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 OAP54971.1 - 0.0041 17.1 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 OAP54971.1 - 0.024 14.1 0.0 0.68 9.4 0.0 2.3 1 1 1 2 2 2 0 Redoxin TSKS PF15358.1 OAP54971.1 - 0.039 12.1 0.0 0.4 8.7 0.0 1.9 2 0 0 2 2 2 0 Testis-specific serine kinase substrate Fungal_trans_2 PF11951.3 OAP54972.1 - 2.7e-07 29.5 5.2 4.1e-05 22.3 0.3 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain C2 PF00168.25 OAP54973.1 - 1.4e-17 63.2 0.1 4.1e-10 39.3 0.0 2.6 2 0 0 2 2 2 2 C2 domain zf-CSL PF05207.8 OAP54974.1 - 2.2e-18 65.4 1.3 4.3e-18 64.5 0.9 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 OAP54974.1 - 7.9e-15 54.3 3.2 2.8e-14 52.6 2.2 1.9 1 1 0 1 1 1 1 DnaJ domain Tmemb_cc2 PF10267.4 OAP54975.1 - 0.11 11.0 4.1 0.11 11.0 2.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein OmpH PF03938.9 OAP54975.1 - 0.27 11.1 3.0 0.28 11.0 2.1 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DAGAT PF03982.8 OAP54976.1 - 1.1e-89 300.0 0.0 1.4e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 OAP54976.1 - 0.09 12.3 0.6 0.16 11.5 0.4 1.3 1 0 0 1 1 1 0 Rer1 family Asp PF00026.18 OAP54977.1 - 5.3e-78 262.4 11.7 6.3e-78 262.2 8.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAP54977.1 - 6.4e-07 29.7 2.1 4.8e-05 23.7 0.2 2.7 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 OAP54977.1 - 2.6e-05 24.2 1.0 8.8e-05 22.5 0.2 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DUF3766 PF12611.3 OAP54977.1 - 0.081 12.4 0.0 2.1 7.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3766) HMG_box PF00505.14 OAP54979.1 - 2.7e-15 56.3 0.1 8.1e-15 54.8 0.1 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.25 OAP54979.1 - 4e-11 42.9 0.0 7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 OAP54979.1 - 2.3e-09 37.4 0.4 2.3e-09 37.4 0.3 1.8 2 0 0 2 2 2 1 HMG-box domain SAM_2 PF07647.12 OAP54979.1 - 4.3e-06 26.4 0.0 7.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.8 OAP54979.1 - 0.099 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) ALIX_LYPXL_bnd PF13949.1 OAP54980.1 - 0.037 12.9 1.4 0.042 12.8 1.0 1.3 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Allexi_40kDa PF05549.6 OAP54980.1 - 0.037 13.3 1.2 0.04 13.1 0.8 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein UPF0184 PF03670.8 OAP54980.1 - 0.038 14.1 0.6 0.044 13.9 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF948 PF06103.6 OAP54980.1 - 0.061 13.1 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2360 PF10152.4 OAP54980.1 - 0.14 12.4 1.9 0.12 12.6 0.7 1.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PilJ PF13675.1 OAP54980.1 - 0.19 12.0 1.2 0.21 11.8 0.8 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term IF-2B PF01008.12 OAP54981.1 - 3.9e-75 252.4 0.6 4.6e-75 252.2 0.4 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Methyltransf_11 PF08241.7 OAP54982.1 - 1.5e-09 38.2 0.0 2.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP54982.1 - 2.9e-08 34.2 0.0 5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP54982.1 - 4.5e-06 26.4 0.0 5.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP54982.1 - 0.00011 22.2 0.0 0.001 19.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP54982.1 - 0.00092 18.3 0.0 0.0019 17.3 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 OAP54982.1 - 0.0016 17.4 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_12 PF08242.7 OAP54982.1 - 0.0018 18.7 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP54982.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 OAP54982.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 OAP54982.1 - 0.022 14.7 0.0 0.056 13.4 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 OAP54982.1 - 0.074 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 OAP54983.1 - 3.9e-16 58.3 0.0 5.2e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAP54983.1 - 0.00098 19.0 0.1 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Methyltransf_23 PF13489.1 OAP54984.1 - 1.4e-21 76.9 0.0 2e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP54984.1 - 9.5e-09 35.8 0.0 6.9e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP54984.1 - 2e-08 34.6 0.0 3.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP54984.1 - 6.9e-08 32.2 0.0 7.5e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP54984.1 - 1.1e-05 25.7 0.0 7.2e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAP54984.1 - 2e-05 23.8 0.0 4.5e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 OAP54984.1 - 5.8e-05 23.3 0.0 0.00016 22.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP54984.1 - 0.0032 17.4 0.0 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 OAP54984.1 - 0.0048 16.1 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 OAP54984.1 - 0.024 13.6 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 OAP54984.1 - 0.032 14.2 0.0 0.064 13.2 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 OAP54984.1 - 0.057 12.5 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) p450 PF00067.17 OAP54985.1 - 3e-44 151.3 0.0 4e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OmdA PF13376.1 OAP54987.1 - 1.1e-14 53.8 3.9 6.3e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 Bacteriocin-protection, YdeI or OmpD-Associated FAD_binding_3 PF01494.14 OAP54988.1 - 4.3e-11 42.4 0.2 0.00038 19.6 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 OAP54988.1 - 0.00085 19.2 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP54988.1 - 0.0027 16.6 0.8 0.028 13.3 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP54988.1 - 0.0029 17.9 0.1 0.017 15.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP54988.1 - 0.02 14.7 0.1 0.045 13.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.16 OAP54988.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_2 PF00890.19 OAP54988.1 - 0.15 10.8 0.1 0.23 10.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Rad60-SLD PF11976.3 OAP54989.1 - 1.7e-16 59.6 0.3 4.3e-13 48.7 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAP54989.1 - 7.2e-07 28.5 0.3 8.4e-06 25.0 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin family Ribosomal_L36e PF01158.13 OAP54990.1 - 1e-41 140.8 6.4 1.2e-41 140.6 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.4 OAP54990.1 - 0.16 11.7 1.8 0.19 11.5 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Peptidase_M20 PF01546.23 OAP54991.1 - 2.3e-17 63.1 0.0 3.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAP54991.1 - 1e-15 57.4 0.0 1.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 OAP54991.1 - 0.0018 18.0 0.0 0.0048 16.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 UCH PF00443.24 OAP54992.1 - 4.9e-22 78.3 0.0 2.5e-21 75.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAP54992.1 - 2.1e-12 46.9 0.3 3.8e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Cpn60_TCP1 PF00118.19 OAP54994.1 - 1.4e-134 449.3 6.4 1.7e-134 449.1 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAD_M PF08527.5 OAP54994.1 - 0.097 12.0 0.2 0.53 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain Pkinase PF00069.20 OAP54995.1 - 4.8e-38 130.7 0.0 7.4e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 OAP54995.1 - 4.3e-29 100.9 0.2 2e-27 95.6 0.0 2.7 2 1 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 OAP54995.1 - 1.9e-16 59.9 0.0 1.2e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 OAP54995.1 - 0.00015 21.1 0.0 0.0053 16.2 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 OAP54995.1 - 0.052 13.0 0.1 0.72 9.2 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain APH PF01636.18 OAP54995.1 - 0.094 12.4 0.0 0.72 9.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-LYAR PF08790.6 OAP54996.1 - 1e-15 57.0 5.2 2.3e-15 55.9 3.6 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger HD PF01966.17 OAP54997.1 - 8e-09 35.5 0.5 1.3e-08 34.8 0.4 1.3 1 0 0 1 1 1 1 HD domain INSIG PF07281.7 OAP54998.1 - 4.1e-47 160.0 1.0 5.4e-47 159.6 0.7 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) VKOR PF07884.9 OAP54998.1 - 0.11 12.4 3.3 0.15 11.8 1.6 1.8 1 1 1 2 2 2 0 Vitamin K epoxide reductase family ECH PF00378.15 OAP54999.1 - 1.1e-43 149.1 0.0 2e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HMGL-like PF00682.14 OAP54999.1 - 1.6e-36 126.1 0.0 2.3e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like AMP-binding PF00501.23 OAP55000.1 - 3.2e-89 299.2 0.0 3.9e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP55000.1 - 2.1e-12 47.8 0.0 7e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Carboxyl_trans PF01039.17 OAP55001.1 - 3.7e-118 395.0 0.0 4.2e-118 394.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Fungal_trans PF04082.13 OAP55002.1 - 1.8e-27 95.8 0.2 2.9e-27 95.1 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55002.1 - 3.8e-08 33.1 10.1 9.9e-08 31.7 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 OAP55003.1 - 8.5e-31 107.0 0.5 1.8e-30 106.0 0.3 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP55003.1 - 3.6e-19 68.0 1.0 6.5e-19 67.1 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAP55003.1 - 6.6e-19 68.5 0.1 4e-18 66.0 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAP55003.1 - 0.0038 17.4 0.8 0.0072 16.5 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.12 OAP55004.1 - 1.7e-68 230.0 0.0 2.6e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 OAP55004.1 - 1e-36 125.3 0.0 2.6e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAP55004.1 - 5.9e-33 113.0 0.0 1.1e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 OAP55004.1 - 6.2e-16 58.6 0.0 1.1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAP55004.1 - 2.3e-13 49.5 0.0 9.5e-13 47.5 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAP55004.1 - 3.1e-11 43.0 0.0 6.8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 OAP55004.1 - 7.5e-11 41.5 2.0 2.8e-10 39.7 1.3 2.1 1 1 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.17 OAP55004.1 - 4e-09 36.0 0.1 8.7e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 OAP55004.1 - 8.1e-08 32.2 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 OAP55004.1 - 0.0019 17.8 0.1 0.024 14.3 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 OAP55004.1 - 0.004 16.6 0.0 0.02 14.3 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Polysacc_synt_4 PF04669.8 OAP55005.1 - 6.9e-22 77.7 0.6 3.5e-21 75.4 0.4 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Complex1_LYR_2 PF13233.1 OAP55005.1 - 0.0062 17.0 0.1 0.0084 16.5 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like ABC_membrane PF00664.18 OAP55006.1 - 1.4e-62 211.6 25.7 2.7e-35 122.1 4.0 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAP55006.1 - 4.9e-60 201.7 0.0 9.9e-30 103.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAP55006.1 - 2.5e-17 62.8 2.8 4.9e-07 29.1 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP55006.1 - 1.9e-11 44.4 0.0 0.059 13.3 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 OAP55006.1 - 1.5e-10 40.4 0.4 0.00062 19.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 OAP55006.1 - 7.1e-10 38.0 5.0 0.0003 19.5 0.1 4.3 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 OAP55006.1 - 4.5e-08 32.7 1.8 0.2 11.0 0.0 3.7 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.1 OAP55006.1 - 5.5e-08 33.0 1.2 0.0051 16.8 1.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 OAP55006.1 - 5.8e-08 32.9 0.2 0.047 13.8 0.0 4.4 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 OAP55006.1 - 1.7e-07 32.0 0.0 0.016 15.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 OAP55006.1 - 5.5e-07 28.9 0.0 0.029 13.5 0.0 2.7 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 OAP55006.1 - 1.6e-06 27.8 8.4 0.03 13.7 0.1 3.8 4 0 0 4 4 3 3 AAA-like domain AAA_33 PF13671.1 OAP55006.1 - 4.5e-05 23.3 0.1 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAP55006.1 - 0.00022 21.5 0.0 0.63 10.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 OAP55006.1 - 0.00041 20.0 2.2 0.26 10.9 0.0 3.0 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 OAP55006.1 - 0.00056 19.7 0.5 1.8 8.5 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 OAP55006.1 - 0.0007 19.1 0.0 0.54 9.7 0.0 3.1 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 OAP55006.1 - 0.00075 19.0 0.0 0.48 9.8 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF3987 PF13148.1 OAP55006.1 - 0.0011 17.6 0.1 0.42 9.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_23 PF13476.1 OAP55006.1 - 0.0016 18.8 0.3 2 8.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 OAP55006.1 - 0.0029 17.4 5.6 0.26 11.0 0.9 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 KaiC PF06745.8 OAP55006.1 - 0.003 16.7 3.2 1.5 7.9 0.0 3.2 3 0 0 3 3 3 2 KaiC Miro PF08477.8 OAP55006.1 - 0.0066 16.9 0.0 10 6.6 0.0 3.1 3 0 0 3 3 2 0 Miro-like protein NACHT PF05729.7 OAP55006.1 - 0.0067 16.1 1.3 1.2 8.7 0.0 3.0 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 OAP55006.1 - 0.0093 15.9 0.1 7.5 6.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 OAP55006.1 - 0.01 15.2 0.3 14 5.1 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 OAP55006.1 - 0.016 14.3 0.2 3.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 OAP55006.1 - 0.027 13.5 0.2 0.97 8.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 OAP55006.1 - 0.031 14.4 0.1 3.2 7.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 OAP55006.1 - 0.046 13.4 0.1 17 5.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 OAP55006.1 - 0.062 12.7 0.6 11 5.5 0.0 3.7 3 1 0 3 3 3 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 OAP55006.1 - 0.13 11.7 0.6 18 4.7 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 OAP55006.1 - 0.14 12.1 0.1 52 3.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain APS_kinase PF01583.15 OAP55006.1 - 0.14 11.7 0.5 4.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_13 PF13166.1 OAP55006.1 - 0.21 10.0 0.3 0.47 8.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 OAP55006.1 - 0.31 9.9 0.3 5.7 5.8 0.0 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.18 OAP55006.1 - 0.35 10.2 5.1 0.62 9.4 0.0 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.15 OAP55006.1 - 0.38 9.4 0.0 25 3.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DUF3328 PF11807.3 OAP55007.1 - 3.4e-21 75.9 0.2 5.4e-21 75.2 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Pro_isomerase PF00160.16 OAP55008.1 - 3.4e-50 170.2 0.2 7.3e-50 169.1 0.2 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 OAP55008.1 - 1.6e-12 46.8 2.7 0.0085 15.9 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Cytokin_check_N PF10407.4 OAP55009.1 - 0.015 14.8 0.1 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus GTP_EFTU PF00009.22 OAP55010.1 - 1.5e-38 132.1 0.0 2.4e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 OAP55010.1 - 1e-35 121.5 0.2 2.2e-35 120.5 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 OAP55010.1 - 1.9e-11 43.8 0.7 4.1e-11 42.8 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAP55010.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAP55010.1 - 0.068 12.9 0.0 0.38 10.5 0.0 2.2 3 0 0 3 3 3 0 Dynamin family adh_short PF00106.20 OAP55011.1 - 1.3e-26 93.5 8.3 1.6e-26 93.1 5.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55011.1 - 8.1e-20 71.6 0.5 1e-19 71.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55011.1 - 7.2e-15 55.1 3.9 9.6e-15 54.6 2.7 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP55011.1 - 0.053 13.3 3.0 0.065 13.0 1.0 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_2 PF00890.19 OAP55012.1 - 6.3e-63 213.0 0.4 6.3e-63 213.0 0.3 2.0 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 OAP55012.1 - 4e-11 42.0 2.3 1e-08 34.1 1.2 3.0 2 1 0 2 2 2 1 HI0933-like protein DAO PF01266.19 OAP55012.1 - 5e-10 38.8 11.6 1.5e-08 33.9 7.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 OAP55012.1 - 5.8e-09 35.5 0.6 9.7e-09 34.7 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP55012.1 - 3e-07 30.5 0.0 4.7e-06 26.6 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 OAP55012.1 - 2.8e-06 26.3 0.0 5.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GIDA PF01134.17 OAP55012.1 - 2.3e-05 23.4 2.3 2.3e-05 23.4 1.6 2.9 3 1 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 OAP55012.1 - 3.3e-05 23.8 2.2 0.00013 21.9 1.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP55012.1 - 3.6e-05 22.9 3.4 0.0001 21.4 0.6 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 OAP55012.1 - 0.0011 19.3 2.6 0.059 13.7 1.7 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP55012.1 - 0.037 14.1 0.4 0.095 12.7 0.2 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP55012.1 - 0.066 12.2 2.3 0.12 11.4 1.6 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 OAP55012.1 - 0.15 10.9 1.8 0.34 9.7 1.3 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 OAP55012.1 - 0.19 11.2 1.1 0.48 9.9 0.8 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAA_hydrolase PF01557.13 OAP55013.1 - 2.9e-55 187.0 0.0 3.5e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.11 OAP55014.1 - 2.7e-28 98.7 25.1 2.7e-28 98.7 17.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily 2TM PF13239.1 OAP55014.1 - 0.16 12.0 0.2 0.16 12.0 0.1 2.8 2 1 1 3 3 3 0 2TM domain Pyr_redox_3 PF13738.1 OAP55015.1 - 3.3e-25 89.3 0.5 7.1e-25 88.2 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP55015.1 - 3.9e-12 45.1 0.0 8.8e-12 43.9 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP55015.1 - 2.3e-10 40.6 0.0 3.2e-08 33.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP55015.1 - 7.8e-10 38.1 0.1 1.2e-07 31.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 OAP55015.1 - 2.5e-07 31.0 0.0 0.023 15.0 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP55015.1 - 1.1e-06 28.5 1.1 8e-06 25.7 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAP55015.1 - 1.9e-06 27.2 0.2 2.9e-05 23.2 0.3 2.4 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 OAP55015.1 - 0.00021 20.3 0.8 0.002 17.0 0.1 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP55015.1 - 0.00039 19.5 0.0 0.0026 16.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 OAP55015.1 - 0.002 18.3 0.0 0.82 9.9 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 OAP55015.1 - 0.007 16.1 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAP55015.1 - 0.0095 14.8 0.5 0.021 13.6 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAP55015.1 - 0.021 13.7 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 OAP55015.1 - 0.041 13.0 0.0 0.97 8.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 OAP55015.1 - 0.041 12.3 0.0 0.12 10.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_2 PF03446.10 OAP55016.1 - 5.1e-27 94.6 0.6 8.1e-27 94.0 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP55016.1 - 5.1e-11 42.7 0.1 1.1e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 OAP55016.1 - 3.8e-09 36.8 2.3 6.2e-09 36.1 0.1 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 OAP55016.1 - 0.00026 20.7 0.3 0.00059 19.6 0.2 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 OAP55016.1 - 0.0018 17.7 1.4 0.0094 15.3 0.4 2.2 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GFO_IDH_MocA PF01408.17 OAP55016.1 - 0.0025 18.3 0.1 0.0081 16.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 OAP55016.1 - 0.0029 17.8 0.1 0.005 17.1 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 OAP55017.1 - 2e-21 76.6 0.0 4.7e-21 75.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55017.1 - 3.6e-14 53.1 0.0 5.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55017.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 KR domain ILVD_EDD PF00920.16 OAP55018.1 - 1.3e-147 492.4 0.0 1.5e-147 492.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family SHOCT PF09851.4 OAP55018.1 - 0.66 9.5 5.2 0.13 11.7 0.3 2.4 2 0 0 2 2 2 0 Short C-terminal domain MRP-L27 PF09809.4 OAP55019.1 - 3.2e-09 36.4 0.3 9e-09 34.9 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L27 DUF3864 PF12980.2 OAP55019.1 - 0.014 15.5 0.2 0.051 13.7 0.2 1.9 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) Glyco_hydro_81 PF03639.8 OAP55021.1 - 1.1e-195 651.6 6.7 1.6e-195 651.1 4.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 OAP55022.1 - 9.8e-165 549.7 50.8 9.8e-165 549.7 35.2 3.0 1 1 1 2 2 2 1 Utp14 protein APH PF01636.18 OAP55023.1 - 3.5e-15 56.4 0.0 7e-15 55.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP55023.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 OAP55023.1 - 0.00025 20.3 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.12 OAP55023.1 - 0.032 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 OAP55023.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.2 OAP55025.1 - 8e-20 70.9 0.0 1.5e-07 31.6 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP55025.1 - 4.6e-13 49.2 2.2 3.9e-08 33.5 0.2 4.8 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP55025.1 - 9.8e-13 47.8 0.1 2.1e-05 24.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP55025.1 - 3.5e-11 42.2 0.4 0.0017 18.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 OAP55025.1 - 1.1e-08 34.4 0.2 0.018 14.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 OAP55025.1 - 0.00089 18.8 0.5 0.013 15.1 0.3 2.3 1 1 0 1 1 1 1 KilA-N domain DIRP PF06584.8 OAP55025.1 - 0.16 11.8 1.6 0.37 10.6 1.1 1.6 1 0 0 1 1 1 0 DIRP Sec8_exocyst PF04048.9 OAP55025.1 - 0.23 11.0 3.7 0.15 11.6 0.9 1.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain OmpH PF03938.9 OAP55025.1 - 0.37 10.7 12.4 0.037 13.9 4.5 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.4 OAP55025.1 - 0.52 10.4 4.6 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 OAP55025.1 - 0.72 9.6 10.5 11 5.7 5.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 OAP55025.1 - 1.8 7.9 10.7 0.21 11.0 3.4 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 FadA PF09403.5 OAP55025.1 - 2.9 7.9 10.0 0.37 10.8 3.7 1.8 2 0 0 2 2 2 0 Adhesion protein FadA TPR_11 PF13414.1 OAP55027.1 - 6.1e-10 38.6 11.5 1.2e-06 28.1 0.0 5.0 5 2 1 6 6 6 2 TPR repeat TPR_1 PF00515.23 OAP55027.1 - 7.7e-07 28.4 0.0 0.17 11.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP55027.1 - 9.8e-05 21.9 9.4 0.42 10.6 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAP55027.1 - 0.00019 21.3 0.1 0.091 13.0 0.0 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP55027.1 - 0.21 11.4 10.3 0.42 10.5 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP55027.1 - 0.51 10.3 13.2 5.8 6.9 0.1 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP55027.1 - 3.2 8.5 0.0 3.2 8.5 0.0 5.9 5 1 0 6 6 6 0 Tetratricopeptide repeat PLDc_2 PF13091.1 OAP55028.1 - 1.8e-15 56.8 0.0 9.5e-07 28.6 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 OAP55028.1 - 1.8e-13 49.7 4.0 7e-08 32.0 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif NAD_binding_7 PF13241.1 OAP55029.1 - 3.1e-29 101.2 0.0 5.3e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 OAP55029.1 - 6.2e-23 79.8 0.1 9.6e-23 79.2 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 OAP55029.1 - 3e-14 51.6 0.2 4.6e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 OAP55029.1 - 0.0025 17.9 0.1 0.0041 17.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP55029.1 - 0.005 16.9 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 OAP55029.1 - 0.088 11.6 0.6 3.2 6.5 0.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pribosyltran_N PF13793.1 OAP55030.1 - 1.1e-40 137.9 0.1 2.9e-40 136.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAP55030.1 - 2.7e-30 105.4 0.0 3e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAP55030.1 - 0.00014 21.5 0.0 0.01 15.5 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Serinc PF03348.10 OAP55031.1 - 1.2e-162 541.5 9.1 1.3e-162 541.3 6.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.11 OAP55032.1 - 3.3e-18 65.5 31.4 3.3e-12 45.7 14.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 OAP55032.1 - 1.3e-10 40.9 1.9 1.3e-10 40.9 1.3 1.9 2 0 0 2 2 2 1 Nodulin-like bZIP_1 PF00170.16 OAP55033.1 - 0.0022 17.9 0.3 0.0057 16.5 0.2 1.7 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.6 OAP55033.1 - 0.012 15.3 2.9 0.016 14.8 0.9 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF2968 PF11180.3 OAP55033.1 - 0.047 13.0 6.9 0.32 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIC PF04977.10 OAP55033.1 - 0.059 12.8 0.1 0.059 12.8 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator SPX PF03105.14 OAP55033.1 - 0.14 11.9 4.3 0.23 11.2 0.0 2.3 2 1 0 2 2 2 0 SPX domain MerR-DNA-bind PF09278.6 OAP55033.1 - 0.4 11.1 7.7 0.39 11.1 0.2 2.3 2 0 0 2 2 2 0 MerR, DNA binding DUF2046 PF09755.4 OAP55033.1 - 0.7 8.7 6.2 0.29 9.9 1.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Ank_5 PF13857.1 OAP55035.1 - 1.1e-06 28.6 0.1 4.7e-05 23.5 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAP55035.1 - 0.00016 21.9 0.0 0.00098 19.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAP55035.1 - 0.00054 19.6 0.0 0.0045 16.7 0.0 2.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 OAP55035.1 - 0.0039 17.3 0.0 0.081 13.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 OAP55035.1 - 0.051 14.1 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Methyltransf_10 PF05971.7 OAP55036.1 - 6.9e-58 196.1 0.0 9.4e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 OAP55036.1 - 2.2e-06 27.6 0.0 4.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP55036.1 - 3.8e-06 27.4 0.0 7.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP55036.1 - 0.00032 20.0 0.0 0.00062 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 OAP55036.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.1 OAP55036.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 OAP55036.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 OAP55036.1 - 0.18 10.8 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Sec7 PF01369.15 OAP55037.1 - 1e-65 220.9 3.2 4.1e-65 219.0 0.2 3.2 4 0 0 4 4 4 1 Sec7 domain Sec7_N PF12783.2 OAP55037.1 - 3.4e-52 176.2 3.9 3.4e-52 176.2 2.7 3.4 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 OAP55037.1 - 1.6e-32 110.8 3.1 2.8e-31 106.8 0.1 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 OAP55038.1 - 8.2e-76 254.2 0.1 1e-75 253.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAP55038.1 - 1.5e-14 53.3 1.1 4.5e-14 51.8 0.7 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 OAP55038.1 - 1.4e-13 50.2 0.4 2.6e-13 49.3 0.3 1.5 1 0 0 1 1 1 1 e3 binding domain Mito_carr PF00153.22 OAP55039.1 - 4e-61 202.7 2.1 3e-20 71.7 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Septin PF00735.13 OAP55040.1 - 3.5e-123 410.1 0.1 3.5e-123 410.1 0.1 2.0 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 OAP55040.1 - 3.3e-07 30.2 0.0 7.1e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAP55040.1 - 5.7e-05 22.3 0.2 0.00048 19.3 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAP55040.1 - 0.00015 21.2 2.0 0.0038 16.6 0.0 3.1 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 OAP55040.1 - 0.00019 20.9 0.8 0.0025 17.3 0.1 2.2 1 1 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 OAP55040.1 - 0.00021 21.6 4.3 0.022 15.0 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 OAP55040.1 - 0.0012 18.8 0.2 0.014 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.11 OAP55040.1 - 0.0026 16.8 1.9 0.004 16.2 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 OAP55040.1 - 0.0033 17.9 0.7 0.012 16.0 0.0 2.3 3 0 0 3 3 2 1 Miro-like protein AAA_22 PF13401.1 OAP55040.1 - 0.0057 16.7 0.0 0.032 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 OAP55040.1 - 0.0088 15.4 0.1 0.041 13.2 0.0 2.2 2 1 0 2 2 2 1 Ras family AAA_29 PF13555.1 OAP55040.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 OAP55040.1 - 0.013 15.0 0.1 2.3 7.6 0.0 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 OAP55040.1 - 0.015 15.0 7.9 0.54 10.0 0.0 3.5 3 1 0 3 3 3 0 Dynamin family FtsK_SpoIIIE PF01580.13 OAP55040.1 - 0.016 14.6 2.2 0.024 14.0 0.0 2.3 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 OAP55040.1 - 0.064 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAP55040.1 - 0.073 13.2 0.6 0.73 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF2937 PF11157.3 OAP55040.1 - 0.08 12.2 4.4 0.21 10.9 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Exonuc_VII_L PF02601.10 OAP55040.1 - 0.11 11.6 6.9 0.26 10.4 4.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit MobB PF03205.9 OAP55040.1 - 0.16 11.6 1.6 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_32 PF13654.1 OAP55040.1 - 1.3 7.5 16.3 0.55 8.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain Phage_GPO PF05929.6 OAP55040.1 - 3.1 6.9 7.9 5.1 6.2 5.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase UPF0121 PF03661.8 OAP55041.1 - 4.3e-14 52.3 4.0 7.3e-14 51.5 2.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) ADH_N PF08240.7 OAP55042.1 - 4.6e-22 77.8 0.3 8.9e-22 76.9 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP55042.1 - 1.7e-17 63.1 0.7 3e-17 62.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP55042.1 - 6.1e-05 23.9 0.1 0.00011 23.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MOZ_SAS PF01853.13 OAP55043.1 - 7.4e-75 250.3 0.1 1.3e-74 249.5 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 OAP55043.1 - 8.4e-05 22.1 6.2 8.4e-05 22.1 4.3 2.0 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 OAP55043.1 - 0.0024 17.5 2.2 0.0056 16.3 1.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 OAP55043.1 - 0.012 15.3 1.2 0.012 15.3 0.9 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Methyltransf_6 PF03737.10 OAP55045.1 - 3.9e-21 75.5 0.4 3.9e-21 75.5 0.3 1.6 2 0 0 2 2 2 1 Demethylmenaquinone methyltransferase Pro_CA PF00484.14 OAP55047.1 - 4.5e-44 150.1 0.0 5.6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DHDPS PF00701.17 OAP55047.1 - 0.11 11.0 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family FAD_binding_3 PF01494.14 OAP55048.1 - 1.6e-18 66.8 3.7 1.6e-16 60.3 2.6 2.3 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAP55048.1 - 9e-09 34.8 0.4 1.8e-08 33.9 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 OAP55048.1 - 1.1e-08 34.3 6.9 0.00083 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP55048.1 - 3.4e-06 27.3 2.6 0.011 16.1 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP55048.1 - 5.2e-05 23.1 2.8 0.00013 21.9 2.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 OAP55048.1 - 0.00013 20.7 2.7 0.031 12.9 0.6 2.8 3 0 0 3 3 3 2 Tryptophan halogenase GIDA PF01134.17 OAP55048.1 - 0.00036 19.5 1.8 0.00052 18.9 1.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 OAP55048.1 - 0.00054 18.9 9.4 0.00067 18.6 4.7 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP55048.1 - 0.0016 18.3 1.2 0.0056 16.5 1.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP55048.1 - 0.0037 16.3 0.6 0.0068 15.5 0.4 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 OAP55048.1 - 0.0042 15.6 5.6 0.011 14.2 2.9 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 OAP55048.1 - 0.0063 16.5 0.1 0.015 15.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP55048.1 - 0.027 13.5 3.6 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 OAP55048.1 - 0.051 13.2 1.4 0.086 12.4 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3603 PF12227.3 OAP55048.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Fungal_trans PF04082.13 OAP55050.1 - 1.2e-38 132.4 0.1 1.8e-38 131.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55050.1 - 3.4e-08 33.2 5.6 7.3e-08 32.2 3.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rotavirus_VP1 PF12289.3 OAP55050.1 - 0.094 12.3 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Rotavirus VP1 structural protein Methyltransf_31 PF13847.1 OAP55051.1 - 4.8e-18 65.2 0.0 6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP55051.1 - 6.8e-15 55.1 0.0 9.2e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP55051.1 - 2.9e-14 53.6 0.0 4.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP55051.1 - 1.7e-13 50.8 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP55051.1 - 8e-13 48.6 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP55051.1 - 5.7e-11 42.7 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP55051.1 - 3.2e-09 36.8 0.0 5.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAP55051.1 - 1.3e-05 25.3 0.0 4e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 OAP55051.1 - 8.5e-05 21.9 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 OAP55051.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 OAP55051.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 OAP55051.1 - 0.00017 20.6 0.0 0.00024 20.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 OAP55051.1 - 0.0002 20.9 0.0 0.00041 19.9 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 OAP55051.1 - 0.00048 19.2 0.0 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 OAP55051.1 - 0.00081 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase TehB PF03848.9 OAP55051.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 OAP55051.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TrkA_N PF02254.13 OAP55051.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain FmrO PF07091.6 OAP55051.1 - 0.077 11.9 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 OAP55051.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 OAP55051.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_5 PF01795.14 OAP55051.1 - 0.16 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family PhoU PF01895.14 OAP55055.1 - 8.2 6.9 7.4 1.6 9.2 0.6 2.8 2 1 0 2 2 2 0 PhoU domain RRS1 PF04939.7 OAP55056.1 - 4.8e-51 172.5 0.2 5.8e-51 172.2 0.1 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Ribosomal_L37 PF08561.5 OAP55056.1 - 0.1 12.1 1.0 0.22 11.0 0.7 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 RhoGAP PF00620.22 OAP55057.1 - 2.1e-29 102.0 0.0 3.5e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.16 OAP55058.1 - 1.1e-55 184.7 7.9 1.8e-12 46.6 0.0 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAP55058.1 - 7.8e-35 119.6 0.0 2.7e-15 56.7 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAP55058.1 - 2e-10 40.6 0.0 0.0017 18.3 0.0 3.5 2 1 1 3 3 3 2 Prenyltransferase-like CTP_transf_2 PF01467.21 OAP55059.1 - 0.0016 18.5 0.3 0.21 11.6 0.2 2.6 3 0 0 3 3 3 2 Cytidylyltransferase WD40 PF00400.27 OAP55060.1 - 2.7e-19 68.2 22.5 1.3e-08 34.3 0.1 6.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Suf PF05843.9 OAP55060.1 - 0.3 10.7 6.7 0.67 9.6 4.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) E1-E2_ATPase PF00122.15 OAP55061.1 - 3.1e-67 225.9 5.6 1.9e-65 220.1 4.3 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAP55061.1 - 4.8e-44 150.0 9.7 5.2e-44 149.9 4.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAP55061.1 - 1e-31 111.0 0.0 1.6e-30 107.1 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP55061.1 - 4e-20 71.5 0.0 9.5e-20 70.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAP55061.1 - 9.5e-20 69.8 0.0 2.8e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 OAP55061.1 - 1.7e-15 57.7 0.0 9.8e-15 55.2 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAP55061.1 - 1.3e-08 34.7 1.9 3.4e-06 26.8 0.7 3.1 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase 14-3-3 PF00244.15 OAP55062.1 - 1.2e-115 384.6 1.2 1.4e-115 384.3 0.9 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 OAP55062.1 - 0.022 14.3 0.6 8.8 5.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_12 PF13424.1 OAP55062.1 - 0.026 14.4 0.5 8.4 6.4 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat HisKA PF00512.20 OAP55062.1 - 0.039 13.9 1.5 5.5 7.0 0.0 3.3 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain MCM_N PF14551.1 OAP55062.1 - 0.2 12.1 1.5 8 6.9 1.0 2.3 1 1 0 1 1 1 0 MCM N-terminal domain S-methyl_trans PF02574.11 OAP55063.1 - 0.096 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Homocysteine S-methyltransferase MFS_1 PF07690.11 OAP55064.1 - 3.6e-28 98.3 28.2 3.6e-28 98.3 19.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP55064.1 - 1e-07 30.9 11.9 1e-07 30.9 8.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter HET PF06985.6 OAP55065.1 - 3.8e-21 75.6 0.0 7.3e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.6 OAP55066.1 - 0.00036 20.3 14.9 0.0015 18.3 7.5 3.2 2 1 0 2 2 2 1 CFEM domain Med15 PF09606.5 OAP55066.1 - 1.2 7.3 6.5 1.4 6.9 4.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ilm1 PF10311.4 OAP55067.1 - 1.5e-17 63.6 0.2 3.1e-09 36.5 0.1 2.4 2 1 0 2 2 2 2 Increased loss of mitochondrial DNA protein 1 TMEM223 PF14640.1 OAP55067.1 - 0.015 15.2 0.8 1.3 8.9 0.2 2.8 1 1 2 3 3 3 0 Transmembrane protein 223 adh_short PF00106.20 OAP55068.1 - 4.1e-19 69.1 0.1 5.7e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP55068.1 - 4.6e-05 23.1 0.1 0.0004 20.0 0.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP55068.1 - 0.041 13.3 0.1 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP55068.1 - 0.12 12.1 0.5 2.1 8.2 0.4 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Spt20 PF12090.3 OAP55069.1 - 0.072 12.4 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Spt20 family DUF563 PF04577.9 OAP55070.1 - 0.059 13.2 0.1 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF563) Filament PF00038.16 OAP55071.1 - 6.4 6.1 17.5 0.16 11.3 3.3 2.8 1 1 1 2 2 2 0 Intermediate filament protein DUF1640 PF07798.6 OAP55072.1 - 3e-64 216.3 6.6 3.6e-64 216.0 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) MerR_1 PF13411.1 OAP55072.1 - 0.095 12.4 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein WXG100 PF06013.7 OAP55072.1 - 1.9 8.5 4.6 6.2 6.9 0.1 2.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Peptidase_M48 PF01435.13 OAP55073.1 - 7.2e-53 179.4 0.1 9.9e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 OAP55073.1 - 0.0008 18.4 0.5 0.0019 17.1 0.1 1.8 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.1 OAP55073.1 - 0.018 14.3 0.5 0.018 14.3 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF2201_N PF13203.1 OAP55073.1 - 0.22 10.6 0.2 0.77 8.8 0.3 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain B PF02216.11 OAP55074.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 B domain BATS PF06968.8 OAP55075.1 - 1.8e-28 98.2 0.0 5.6e-28 96.6 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 OAP55075.1 - 2.8e-15 56.8 0.1 5.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Ank PF00023.25 OAP55077.1 - 0.0036 17.0 0.0 4.1 7.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 OAP55077.1 - 0.0057 16.9 0.0 0.41 11.0 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP55077.1 - 0.086 13.3 0.0 16 6.1 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) SHR3_chaperone PF08229.6 OAP55078.1 - 7.5e-75 250.2 0.0 9.6e-75 249.8 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 MFS_1 PF07690.11 OAP55078.1 - 0.029 13.0 3.7 0.17 10.5 3.5 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily Sigma70_r4_2 PF08281.7 OAP55081.1 - 0.033 13.6 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Aldose_epim PF01263.15 OAP55082.1 - 2.3e-42 145.1 0.0 2.6e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4432 PF14486.1 OAP55082.1 - 0.00018 20.1 0.0 0.00026 19.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4432) AT_hook PF02178.14 OAP55083.1 - 0.00041 19.7 8.4 0.015 14.8 1.0 3.2 2 0 0 2 2 2 2 AT hook motif Acetyltransf_3 PF13302.1 OAP55085.1 - 1.7e-16 60.6 0.0 2.1e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP55085.1 - 8.5e-10 38.7 0.0 1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP55085.1 - 1.2e-05 25.2 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 OAP55085.1 - 0.01 15.6 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 OAP55086.1 - 9.6e-43 146.2 46.8 2.2e-41 141.7 31.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP55086.1 - 4e-14 51.7 23.6 5.9e-14 51.1 16.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAP55086.1 - 8.9e-12 44.3 6.8 8.9e-12 44.3 4.7 3.9 3 1 1 4 4 4 3 Sugar (and other) transporter ABC2_membrane_5 PF13346.1 OAP55086.1 - 3.5 6.8 25.1 0.58 9.4 4.2 3.4 3 1 0 3 3 3 0 ABC-2 family transporter protein Prefoldin_3 PF13758.1 OAP55087.1 - 5.7e-24 83.7 0.7 2e-23 81.9 0.5 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 OAP55087.1 - 1.4e-11 45.1 0.2 1.4e-11 45.1 0.1 4.8 4 1 0 4 4 4 2 Domain of unknown function (DUF3835) HR1 PF02185.11 OAP55087.1 - 0.00057 19.5 0.9 0.049 13.3 0.1 3.0 2 0 0 2 2 2 1 Hr1 repeat MAT1 PF06391.8 OAP55088.1 - 2.1e-24 86.2 5.3 2.8e-24 85.8 3.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 OAP55088.1 - 3.5e-05 23.3 3.2 7.3e-05 22.3 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP55088.1 - 0.00018 21.4 6.4 0.00033 20.6 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP55088.1 - 0.00079 19.2 5.0 0.0015 18.2 3.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAP55088.1 - 0.0019 17.8 8.5 0.0076 15.9 5.9 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAP55088.1 - 0.0031 17.1 5.4 0.0053 16.3 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PCI PF01399.22 OAP55089.1 - 7.4e-13 48.7 0.0 3.4e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 PCI domain ParB PF08775.5 OAP55089.1 - 0.1 12.9 0.6 0.66 10.3 0.4 2.1 2 0 0 2 2 2 0 ParB family HSA PF07529.8 OAP55090.1 - 1.6e-19 69.4 1.5 1.6e-19 69.4 1.1 4.1 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 OAP55090.1 - 4.1e-17 62.0 2.2 3e-16 59.2 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAP55090.1 - 0.00062 19.7 0.0 0.0038 17.2 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4408 PF14364.1 OAP55090.1 - 0.64 9.6 1.5 1.2 8.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) Ribosomal_L34 PF00468.12 OAP55090.1 - 4 7.1 9.7 1.8 8.3 0.2 2.8 2 0 0 2 2 2 0 Ribosomal protein L34 WD40 PF00400.27 OAP55091.1 - 8.9e-13 47.5 1.5 0.0027 17.5 0.0 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ADK PF00406.17 OAP55092.1 - 9.3e-45 152.1 0.0 1.1e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 OAP55092.1 - 2.4e-11 44.0 0.0 3.2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAP55092.1 - 4e-08 33.2 0.1 3.8e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP55092.1 - 4.9e-07 30.5 0.0 6.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 OAP55092.1 - 0.00054 19.3 0.1 0.76 9.1 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 OAP55092.1 - 0.061 12.4 0.1 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 OAP55092.1 - 0.07 12.8 0.1 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Part of AAA domain Clathrin PF00637.15 OAP55093.1 - 1.3e-205 673.2 37.8 8.9e-34 116.1 0.7 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 OAP55093.1 - 2e-32 110.8 2.6 4.6e-32 109.7 0.4 2.9 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.15 OAP55093.1 - 5.5e-24 82.7 2.2 7.6e-05 22.7 0.0 7.2 7 0 0 7 7 7 5 Clathrin propeller repeat TPR_7 PF13176.1 OAP55093.1 - 2.1e-05 23.9 10.7 5.8 6.9 0.0 7.8 7 0 0 7 7 7 2 Tetratricopeptide repeat Vps39_1 PF10366.4 OAP55093.1 - 0.00017 21.5 7.2 0.46 10.5 0.0 5.5 5 0 0 5 5 4 1 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.23 OAP55093.1 - 0.00024 20.5 3.3 4.1 7.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Clathrin-link PF09268.5 OAP55093.1 - 0.00083 18.3 3.1 0.0026 16.7 0.5 2.6 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 OAP55093.1 - 0.0037 16.1 11.9 0.2 10.3 0.2 4.3 4 0 0 4 4 4 2 Coatomer WD associated region TPR_11 PF13414.1 OAP55093.1 - 0.016 14.8 7.5 17 5.1 0.0 6.2 5 0 0 5 5 5 0 TPR repeat TPR_12 PF13424.1 OAP55093.1 - 0.027 14.3 13.2 5.9 6.8 0.0 7.4 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF1720 PF08226.6 OAP55093.1 - 0.15 12.1 7.0 0.022 14.7 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) TPR_14 PF13428.1 OAP55093.1 - 0.33 11.6 21.0 5.9 7.8 0.0 10.4 14 0 0 14 14 10 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP55093.1 - 0.79 9.7 18.0 6.7 6.8 0.0 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.12 OAP55094.1 - 5e-82 274.2 0.1 7.6e-82 273.6 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 OAP55094.1 - 2.7e-68 229.3 0.1 4.6e-68 228.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 OAP55094.1 - 5.9e-35 119.7 0.1 1.4e-34 118.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAP55094.1 - 6e-30 103.3 0.0 1.5e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 OAP55094.1 - 4.5e-26 91.9 0.0 7.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 OAP55094.1 - 4e-19 69.0 0.1 8.7e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 OAP55094.1 - 2e-18 65.7 3.7 2e-18 65.7 2.6 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 OAP55094.1 - 2.7e-15 55.9 0.0 1.3e-14 53.7 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAP55094.1 - 5.6e-11 42.2 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 OAP55094.1 - 1.8e-10 40.3 3.9 6.8e-06 25.6 0.1 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like RimK PF08443.6 OAP55094.1 - 6.8e-08 32.2 0.0 1.6e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 OAP55094.1 - 2.5e-07 30.2 0.1 5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 OAP55094.1 - 1.1e-05 24.9 0.1 0.038 13.2 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 OAP55094.1 - 2.9e-05 23.4 0.1 0.11 11.5 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 OAP55094.1 - 3.5e-05 23.7 0.0 6.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 OAP55094.1 - 0.00011 22.4 0.2 0.0049 17.1 0.1 3.2 2 1 1 3 3 3 1 HlyD family secretion protein GARS_A PF01071.14 OAP55094.1 - 0.03 13.8 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.1 OAP55094.1 - 0.1 12.3 1.3 0.7 9.6 0.9 2.2 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 OAP55094.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 OAP55094.1 - 0.16 11.6 2.0 0.6 9.8 0.3 2.8 3 1 1 4 4 3 0 Glycine cleavage H-protein ASFV_J13L PF05568.6 OAP55095.1 - 0.093 12.2 1.6 0.1 12.0 1.1 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein CAF1-p150_C2 PF15539.1 OAP55095.1 - 0.15 11.2 0.5 0.15 11.1 0.4 1.1 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term SspP PF08179.7 OAP55095.1 - 0.22 11.7 1.1 0.38 10.9 0.1 1.8 2 0 0 2 2 2 0 Small acid-soluble spore protein P family MPC PF03650.8 OAP55096.1 - 7.4e-33 113.0 0.2 9.9e-33 112.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF1122 PF06557.6 OAP55096.1 - 0.052 12.7 0.6 0.078 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) Med6 PF04934.9 OAP55096.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 MED6 mediator sub complex component Rif1_N PF12231.3 OAP55097.1 - 1.9e-101 339.7 0.6 2.7e-101 339.2 0.4 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Desmo_N PF06771.6 OAP55097.1 - 0.18 11.7 0.4 5.1 7.0 0.0 2.8 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus Ric8 PF10165.4 OAP55098.1 - 1.1e-101 340.8 1.6 1.3e-101 340.6 1.1 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn SAC3_GANP PF03399.11 OAP55098.1 - 0.046 13.2 0.2 6 6.3 0.0 2.6 2 1 0 2 2 2 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family GHMP_kinases_N PF00288.21 OAP55099.1 - 3.9e-19 68.4 0.2 1.3e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAP55099.1 - 1.6e-07 31.4 0.0 3.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 OAP55099.1 - 0.013 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature PPTA PF01239.17 OAP55100.1 - 6.9e-41 135.9 11.1 8.4e-08 31.2 0.0 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 OAP55100.1 - 0.047 14.3 0.4 4.2 8.1 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 OAP55101.1 - 5e-56 190.1 0.0 7.4e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AICARFT_IMPCHas PF01808.13 OAP55102.1 - 9.3e-111 369.8 0.0 1.2e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 OAP55102.1 - 1.9e-23 82.1 0.0 3.6e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain FixQ PF05545.6 OAP55104.1 - 5 6.8 6.2 0.52 9.9 0.2 2.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ AphA_like PF14557.1 OAP55105.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Pam17 PF08566.5 OAP55106.1 - 7.9e-58 194.9 0.0 1.1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Colicin_V PF02674.11 OAP55106.1 - 0.01 15.6 0.1 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Colicin V production protein DUF204 PF02659.10 OAP55106.1 - 0.41 10.7 2.5 0.9 9.7 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF PAP1 PF08601.5 OAP55106.1 - 0.5 10.0 3.7 0.64 9.6 2.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Fungal_trans_2 PF11951.3 OAP55107.1 - 6.7e-60 202.7 1.1 1e-59 202.1 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55107.1 - 4.6e-09 36.0 9.3 8.3e-09 35.2 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Far-17a_AIG1 PF04750.9 OAP55108.1 - 8.7e-67 224.1 12.5 9.9e-67 223.9 8.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein ATP1G1_PLM_MAT8 PF02038.11 OAP55108.1 - 0.015 14.3 0.1 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family PALP PF00291.20 OAP55109.1 - 4.4e-30 104.9 0.1 5.5e-30 104.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 OAP55109.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 LytB protein DUF4381 PF14316.1 OAP55111.1 - 0.017 15.2 0.5 0.036 14.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) UPF0104 PF03706.8 OAP55111.1 - 0.019 14.2 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) RR_TM4-6 PF06459.7 OAP55111.1 - 0.099 12.5 2.0 0.14 12.0 1.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SieB PF14163.1 OAP55111.1 - 0.17 11.4 0.2 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B HMG_CoA_synt_N PF01154.12 OAP55112.1 - 0.045 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal SSP160 PF06933.6 OAP55112.1 - 2.8 5.8 28.4 3.4 5.5 19.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAD_binding_3 PF01494.14 OAP55113.1 - 1.2e-09 37.6 0.1 1.3e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP55113.1 - 0.00015 20.8 0.0 0.00037 19.5 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 OAP55113.1 - 0.011 14.6 0.1 0.016 14.1 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAP55113.1 - 0.061 11.9 0.0 0.34 9.4 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.5 OAP55113.1 - 0.13 11.0 0.0 0.96 8.2 0.0 2.0 2 1 0 2 2 2 0 Squalene epoxidase ADH_zinc_N PF00107.21 OAP55114.1 - 9.2e-25 86.6 0.2 1.7e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP55114.1 - 4e-24 84.4 5.4 7.3e-24 83.6 3.7 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 OAP55114.1 - 0.046 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S28 PF05577.7 OAP55115.1 - 2.6e-40 138.3 0.0 4.2e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 OAP55116.1 - 4.9e-08 33.1 2.1 1.2e-07 31.8 1.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55116.1 - 8.3e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family SyrA PF11089.3 OAP55116.1 - 0.03 14.1 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Exopolysaccharide production repressor DUF3336 PF11815.3 OAP55117.1 - 2e-29 101.9 0.1 3.3e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 OAP55117.1 - 9e-23 81.2 0.0 3.1e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase Prismane PF03063.15 OAP55117.1 - 0.036 12.4 0.0 0.063 11.6 0.0 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family mRNA_triPase PF02940.10 OAP55118.1 - 1.8e-46 158.6 0.0 2.6e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PC_rep PF01851.17 OAP55119.1 - 1.4e-33 113.2 12.6 6.1e-09 35.6 0.0 9.8 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 OAP55119.1 - 4.4e-17 62.1 2.0 1.3e-11 44.6 0.1 4.6 3 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 OAP55119.1 - 7.2e-09 35.8 0.6 2.9e-05 24.3 0.0 4.3 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 OAP55119.1 - 2e-08 33.5 0.0 1.1 9.5 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 OAP55119.1 - 0.2 12.2 3.2 1.4 9.6 0.1 3.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Ribosomal_S8 PF00410.14 OAP55120.1 - 2e-21 76.1 0.0 3.5e-21 75.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 Pkinase_Tyr PF07714.12 OAP55121.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Zn_clus PF00172.13 OAP55122.1 - 5.2e-05 23.0 10.7 0.0001 22.1 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 OAP55123.1 - 3.7e-42 145.1 0.5 8.8e-42 143.9 0.3 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAP55123.1 - 3.6e-20 73.1 0.7 2.4e-14 54.0 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 OAP55123.1 - 1.2e-16 60.9 0.2 5.6e-14 52.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP55123.1 - 1.3e-10 40.8 0.0 4.3e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 OAP55123.1 - 8.2e-05 21.6 0.0 0.00042 19.3 0.0 2.0 2 0 0 2 2 2 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.15 OAP55124.1 - 1.5e-55 188.3 37.3 7.1e-55 186.0 25.9 1.8 1 1 0 1 1 1 1 Permease family Acetyltransf_1 PF00583.19 OAP55125.1 - 6.5e-10 38.9 0.1 2.2e-09 37.2 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP55125.1 - 2.8e-09 37.0 0.0 7.8e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP55125.1 - 3.1e-05 24.0 0.0 9.6e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP55125.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 OAP55125.1 - 0.0026 17.6 0.2 0.024 14.4 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Amidoligase_2 PF12224.3 OAP55126.1 - 6.9e-17 61.8 1.3 3e-07 30.3 0.2 2.9 2 1 0 2 2 2 2 Putative amidoligase enzyme MFS_1 PF07690.11 OAP55127.1 - 9e-24 83.8 28.3 9e-24 83.8 19.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PBP PF01161.15 OAP55129.1 - 4e-14 52.6 0.1 5.9e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Spike_rec_bind PF09408.5 OAP55129.1 - 0.091 12.2 0.1 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Spike receptor binding domain Kei1 PF08552.6 OAP55129.1 - 0.85 9.2 4.5 1.3 8.5 3.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 F-box-like PF12937.2 OAP55130.1 - 0.0016 18.1 1.1 0.0098 15.6 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAP55130.1 - 0.079 12.6 1.7 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 F-box domain DZR PF12773.2 OAP55130.1 - 0.85 9.4 6.4 6.7 6.6 4.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon TniQ PF06527.6 OAP55130.1 - 1.2 9.3 6.8 8.9 6.5 0.6 2.3 1 1 1 2 2 2 0 TniQ ADH_zinc_N PF00107.21 OAP55131.1 - 2.4e-17 62.6 0.2 1.2e-16 60.4 0.2 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP55131.1 - 1.3e-12 48.6 0.0 2.9e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP55131.1 - 5.1e-08 32.6 0.0 3e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SnoaL_2 PF12680.2 OAP55131.1 - 6.5e-05 23.2 0.0 0.0002 21.7 0.0 1.9 1 0 0 1 1 1 1 SnoaL-like domain DUF1237 PF06824.6 OAP55132.1 - 5.1e-15 54.9 0.0 3.3e-14 52.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1237) Fungal_trans PF04082.13 OAP55132.1 - 2.5e-12 46.2 0.1 5.8e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP55133.1 - 8.5e-31 106.9 23.5 8.5e-31 106.9 16.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1127 PF06568.6 OAP55133.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) RPAP1_N PF08621.5 OAP55133.1 - 0.15 11.6 0.3 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal Vma12 PF11712.3 OAP55133.1 - 0.7 9.5 3.3 4 7.1 2.3 2.1 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase APG5 PF04106.7 OAP55135.1 - 8.2e-50 169.0 0.0 1.1e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Herpes_LMP2 PF07415.6 OAP55138.1 - 0.28 9.7 1.0 0.39 9.2 0.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Sugar_tr PF00083.19 OAP55139.1 - 2.2e-77 260.5 21.2 2.5e-77 260.3 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55139.1 - 6.5e-22 77.7 25.7 6.5e-22 77.7 17.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily FimP PF09766.4 OAP55140.1 - 3.1e-19 69.2 7.8 3.8e-19 68.9 5.4 1.1 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 OAP55140.1 - 0.0053 16.5 1.1 0.0053 16.5 0.8 3.6 2 2 2 4 4 4 1 K-box region SeqA PF03925.8 OAP55140.1 - 0.21 11.2 3.0 0.11 12.1 0.2 1.7 2 0 0 2 2 2 0 SeqA protein DUF4200 PF13863.1 OAP55140.1 - 0.45 10.4 14.0 0.052 13.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) E1_dh PF00676.15 OAP55140.1 - 0.94 8.1 3.0 1.6 7.3 2.1 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component HisKA_3 PF07730.8 OAP55140.1 - 2.7 8.4 9.3 3.1 8.2 0.6 3.0 2 1 1 3 3 3 0 Histidine kinase APG6 PF04111.7 OAP55140.1 - 5.2 6.0 11.9 3 6.8 1.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Methyltransf_12 PF08242.7 OAP55141.1 - 1.7e-13 50.8 0.0 5.6e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP55141.1 - 2.1e-12 47.3 0.0 6.5e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP55141.1 - 3.3e-12 46.4 0.0 5.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP55141.1 - 6.2e-11 42.5 0.0 1.9e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP55141.1 - 4e-10 39.4 0.0 5.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP55141.1 - 5.4e-09 36.6 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP55141.1 - 6.7e-08 31.9 0.0 9.8e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 OAP55141.1 - 1.1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP55141.1 - 0.0006 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF3419 PF11899.3 OAP55141.1 - 0.003 16.3 0.0 0.0041 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 OAP55141.1 - 0.0032 18.2 0.0 0.016 15.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 OAP55141.1 - 0.0059 16.2 0.0 0.12 11.9 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 OAP55141.1 - 0.014 14.4 0.0 0.089 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.15 OAP55141.1 - 0.039 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.6 OAP55141.1 - 0.043 13.2 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) GCD14 PF08704.5 OAP55141.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit NNMT_PNMT_TEMT PF01234.12 OAP55141.1 - 0.12 11.2 0.0 2.2 7.1 0.0 2.1 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.4 OAP55141.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase HlyIII PF03006.15 OAP55142.1 - 2e-55 187.6 23.7 2.5e-55 187.3 16.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related Fungal_trans_2 PF11951.3 OAP55143.1 - 1.4e-06 27.1 0.3 2.7e-06 26.2 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Arrestin_N PF00339.24 OAP55146.1 - 3.5e-09 36.6 0.0 2.3e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Filament_head PF04732.9 OAP55146.1 - 0.037 14.7 2.5 0.15 12.8 1.7 2.0 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region SLAIN PF15301.1 OAP55147.1 - 0.057 12.5 0.1 0.057 12.5 0.1 1.9 1 1 0 2 2 2 0 SLAIN motif-containing family Hamartin PF04388.7 OAP55147.1 - 4.2 5.9 5.4 5.2 5.6 3.7 1.1 1 0 0 1 1 1 0 Hamartin protein Fungal_trans PF04082.13 OAP55148.1 - 6.2e-29 100.6 0.4 1.1e-28 99.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55148.1 - 1.2e-09 37.8 8.0 2.5e-09 36.9 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF997 PF06196.7 OAP55148.1 - 0.029 13.8 0.2 0.067 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF997) HD_4 PF13328.1 OAP55149.1 - 0.063 12.9 0.3 0.11 12.2 0.2 1.4 1 1 0 1 1 1 0 HD domain MFS_1 PF07690.11 OAP55151.1 - 1.8e-15 56.5 36.1 3.7e-12 45.6 16.8 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily LRV PF01816.12 OAP55152.1 - 0.02 15.0 5.4 0.039 14.1 3.7 1.5 1 0 0 1 1 1 0 Leucine rich repeat variant TPR_14 PF13428.1 OAP55152.1 - 0.022 15.3 0.4 0.039 14.5 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Baculo_11_kDa PF06143.6 OAP55152.1 - 0.68 9.3 3.1 1 8.7 2.1 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DLH PF01738.13 OAP55153.1 - 2.6e-15 56.2 0.0 3.2e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP55153.1 - 6.1e-08 32.5 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP55153.1 - 1.9e-05 24.6 4.4 0.00019 21.4 0.9 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 OAP55155.1 - 9.2e-06 24.4 0.1 1.5e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain GDE_N_bis PF14742.1 OAP55155.1 - 0.076 12.3 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes Ferritin_2 PF13668.1 OAP55156.1 - 7.2e-14 51.9 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Peptidase_M20 PF01546.23 OAP55157.1 - 7.6e-09 35.3 0.3 1.1e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAP55157.1 - 6.2e-08 32.3 0.0 4.3e-07 29.6 0.0 2.4 2 1 0 2 2 2 1 Peptidase dimerisation domain DUF876 PF05936.7 OAP55157.1 - 0.036 12.5 0.0 0.05 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) DUF4286 PF14114.1 OAP55158.1 - 5.6e-05 23.3 0.1 0.048 13.9 0.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4286) EthD PF07110.6 OAP55158.1 - 0.11 13.4 0.1 0.46 11.4 0.0 2.0 2 0 0 2 2 2 0 EthD domain DUF1100 PF06500.6 OAP55159.1 - 4.4e-12 45.3 0.0 5.6e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 OAP55159.1 - 5.4e-11 42.4 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP55159.1 - 1e-09 38.6 0.1 2.4e-09 37.4 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAP55159.1 - 2.2e-07 30.5 0.0 3.9e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 OAP55159.1 - 5.9e-07 28.9 0.0 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 OAP55159.1 - 9.8e-06 25.1 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 2 Putative esterase BAAT_C PF08840.6 OAP55159.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 OAP55159.1 - 0.022 14.3 1.6 2 7.8 0.3 3.0 2 1 1 3 3 3 0 alpha/beta hydrolase fold NUC173 PF08161.7 OAP55159.1 - 0.053 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 NUC173 domain DLH PF01738.13 OAP55159.1 - 0.073 12.3 0.0 0.51 9.5 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Ank_2 PF12796.2 OAP55160.1 - 4.2e-54 180.8 1.1 2.1e-16 60.0 0.0 5.4 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 OAP55160.1 - 9.2e-44 145.1 11.5 4.8e-08 32.4 0.0 10.0 10 0 0 10 10 9 6 Ankyrin repeat Ank_3 PF13606.1 OAP55160.1 - 2.8e-35 116.7 6.5 1.3e-05 24.9 0.1 10.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 OAP55160.1 - 3.6e-34 116.0 17.9 7.2e-11 41.9 0.8 8.5 4 3 5 9 9 9 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP55160.1 - 1.2e-27 95.7 10.0 7.3e-07 29.5 0.2 8.6 5 3 5 10 10 10 7 Ankyrin repeats (many copies) NACHT PF05729.7 OAP55160.1 - 3e-10 40.0 0.1 6.5e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP55160.1 - 4e-07 30.2 0.4 6.1e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP55160.1 - 4e-07 30.2 0.2 1.4e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 OAP55160.1 - 0.00059 18.7 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 OAP55160.1 - 0.0044 17.1 0.1 0.017 15.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase DEAD PF00270.24 OAP55160.1 - 0.023 14.2 0.0 0.37 10.2 0.0 2.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase IDO PF01231.13 OAP55162.1 - 2.4e-101 339.2 0.0 5.6e-101 338.0 0.0 1.5 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Trp_dioxygenase PF03301.8 OAP55162.1 - 0.085 11.9 0.8 3.5 6.6 0.1 2.5 1 1 1 2 2 2 0 Tryptophan 2,3-dioxygenase bZIP_1 PF00170.16 OAP55164.1 - 1.7e-07 31.0 9.1 2.8e-07 30.4 6.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor EGF_2 PF07974.8 OAP55164.1 - 0.015 15.4 3.4 0.026 14.6 2.3 1.3 1 0 0 1 1 1 0 EGF-like domain Inhibitor_I34 PF10466.4 OAP55164.1 - 0.025 14.6 0.1 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopepsin inhibitor I34 DUF2721 PF11026.3 OAP55164.1 - 0.32 10.6 1.2 0.55 9.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DivIC PF04977.10 OAP55164.1 - 2.4 7.7 9.1 1.4 8.4 0.5 2.2 1 1 1 2 2 2 0 Septum formation initiator SNF2_N PF00176.18 OAP55165.1 - 1e-57 195.2 0.0 2.9e-57 193.7 0.0 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 OAP55165.1 - 8.2e-08 31.9 11.0 2.8e-07 30.2 7.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAP55165.1 - 2.2e-07 30.4 8.2 5.9e-07 29.0 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP55165.1 - 1.7e-06 27.9 10.8 1.7e-06 27.9 7.5 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP55165.1 - 4.6e-06 26.1 10.7 1.4e-05 24.5 7.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP55165.1 - 3e-05 23.6 10.2 3e-05 23.6 7.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 OAP55165.1 - 0.0004 19.8 5.5 0.00095 18.6 3.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.26 OAP55165.1 - 0.0097 15.7 0.1 0.04 13.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 OAP55165.1 - 0.014 15.2 9.1 0.032 14.0 6.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 OAP55165.1 - 0.053 13.6 6.3 0.17 11.9 4.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-P11 PF03854.9 OAP55165.1 - 0.27 10.7 7.8 0.63 9.5 5.4 1.6 1 0 0 1 1 1 0 P-11 zinc finger SGL PF08450.7 OAP55167.1 - 0.00019 20.8 1.7 0.041 13.2 0.1 2.9 3 1 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region GSDH PF07995.6 OAP55167.1 - 0.0022 17.1 0.5 0.012 14.7 0.3 2.5 1 1 1 2 2 2 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 OAP55167.1 - 0.0026 17.6 0.0 3.2 7.8 0.0 3.3 2 0 0 2 2 2 2 NHL repeat SBBP PF06739.6 OAP55167.1 - 0.057 13.2 0.0 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Beta-propeller repeat Arylesterase PF01731.15 OAP55167.1 - 0.1 12.5 0.0 18 5.4 0.0 2.9 3 0 0 3 3 3 0 Arylesterase ABC_tran PF00005.22 OAP55168.1 - 4.4e-47 159.8 1.0 2.7e-22 79.5 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 OAP55168.1 - 3.7e-21 74.7 6.1 3.7e-21 74.7 4.2 3.9 4 1 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 OAP55168.1 - 1.1e-15 58.3 0.3 0.0033 17.4 0.0 4.8 5 0 0 5 5 5 3 AAA domain SMC_N PF02463.14 OAP55168.1 - 1.5e-10 40.7 0.7 0.031 13.5 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 OAP55168.1 - 2.5e-08 34.7 0.8 0.013 16.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 OAP55168.1 - 4.9e-07 29.0 0.0 0.022 13.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 OAP55168.1 - 2.6e-06 27.9 0.2 0.021 15.3 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_22 PF13401.1 OAP55168.1 - 4.3e-06 26.9 0.0 0.057 13.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 OAP55168.1 - 6e-06 25.7 0.8 0.066 12.7 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 OAP55168.1 - 1.4e-05 24.9 0.0 0.027 14.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 OAP55168.1 - 2.9e-05 24.1 3.5 0.023 14.6 0.1 3.5 4 0 0 4 4 3 2 AAA ATPase domain AAA_15 PF13175.1 OAP55168.1 - 2.9e-05 23.2 6.9 0.17 10.9 0.0 4.6 5 1 0 5 5 5 2 AAA ATPase domain MobB PF03205.9 OAP55168.1 - 3.8e-05 23.4 0.1 0.2 11.3 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 OAP55168.1 - 4e-05 23.5 0.1 0.22 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 OAP55168.1 - 0.00017 22.0 16.3 0.04 14.2 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.1 OAP55168.1 - 0.00027 21.2 4.9 0.39 11.0 0.0 3.5 5 0 0 5 5 2 2 AAA domain AAA PF00004.24 OAP55168.1 - 0.00065 19.9 0.1 0.7 10.0 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 OAP55168.1 - 0.00065 19.3 0.7 0.58 9.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 OAP55168.1 - 0.00088 18.7 0.2 1.4 8.3 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 OAP55168.1 - 0.0013 18.7 4.8 0.096 12.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 OAP55168.1 - 0.0014 18.5 0.0 1.4 8.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 OAP55168.1 - 0.0028 16.4 5.2 1.2 7.8 0.0 3.2 3 0 0 3 3 3 2 ArgK protein RNA_helicase PF00910.17 OAP55168.1 - 0.0044 17.1 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 OAP55168.1 - 0.0048 16.7 8.2 1.5 8.6 1.2 3.9 3 1 0 3 3 2 1 Dynamin family AAA_25 PF13481.1 OAP55168.1 - 0.006 16.0 0.0 4.7 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 OAP55168.1 - 0.0067 15.5 1.3 0.43 9.6 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin NTPase_1 PF03266.10 OAP55168.1 - 0.0074 16.0 0.1 1.4 8.6 0.1 2.7 2 0 0 2 2 2 1 NTPase cobW PF02492.14 OAP55168.1 - 0.01 15.3 1.0 1.5 8.2 0.3 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 OAP55168.1 - 0.011 15.2 0.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 OAP55168.1 - 0.021 14.4 0.1 4.3 6.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 OAP55168.1 - 0.036 12.9 0.0 4.7 5.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.1 OAP55168.1 - 0.048 13.5 0.1 22 5.0 0.1 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 OAP55168.1 - 0.053 13.2 0.2 6.6 6.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAP55168.1 - 0.075 12.7 0.1 3.6 7.4 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain PduV-EutP PF10662.4 OAP55168.1 - 0.084 12.3 0.1 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3824 PF12868.2 OAP55168.1 - 0.2 12.5 0.2 0.2 12.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF87 PF01935.12 OAP55168.1 - 0.85 9.3 12.6 2.3 7.9 0.0 4.5 5 0 0 5 5 4 0 Domain of unknown function DUF87 DUF2346 PF09803.4 OAP55168.1 - 5.6 6.9 8.1 0.39 10.5 1.3 2.2 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2346) ESSS PF10183.4 OAP55170.1 - 2.4e-15 56.8 2.1 2.9e-15 56.5 1.4 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Raffinose_syn PF05691.7 OAP55171.1 - 1.8e-56 191.1 1.0 6.9e-49 166.0 0.1 2.8 1 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 OAP55171.1 - 0.00018 20.3 0.2 0.00029 19.6 0.2 1.2 1 0 0 1 1 1 1 Melibiase Abhydrolase_6 PF12697.2 OAP55173.1 - 2.1e-13 50.6 0.2 3.4e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55173.1 - 3.3e-12 46.3 0.0 6.8e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP55173.1 - 4.1e-06 26.5 0.0 3.7e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 OAP55173.1 - 0.00013 21.5 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAP55173.1 - 0.0017 18.1 0.0 0.0087 15.9 0.0 2.1 1 1 0 1 1 1 1 Putative lysophospholipase Virul_fac_BrkB PF03631.10 OAP55174.1 - 0.28 10.5 0.9 0.39 10.0 0.7 1.1 1 0 0 1 1 1 0 Virulence factor BrkB Mitofilin PF09731.4 OAP55175.1 - 1.5e-147 492.8 9.9 1.9e-147 492.4 6.9 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Pescadillo_N PF06732.6 OAP55176.1 - 6.3e-110 366.8 0.5 6.3e-110 366.8 0.3 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 OAP55176.1 - 3.8e-09 36.5 0.0 2.1e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 OAP55177.1 - 4.3e-106 355.0 25.0 5e-106 354.7 17.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U IBV_3C PF03620.8 OAP55177.1 - 0.48 10.3 2.8 6 6.8 0.0 3.0 2 0 0 2 2 2 0 IBV 3C protein Acetyltransf_1 PF00583.19 OAP55178.1 - 1.5e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP55178.1 - 0.00028 20.9 0.0 0.00056 20.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAP55178.1 - 0.00046 20.2 0.1 0.00069 19.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAP55178.1 - 0.021 14.9 0.1 0.05 13.7 0.1 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP55178.1 - 0.055 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Aldedh PF00171.17 OAP55179.1 - 3.2e-163 543.3 0.5 3.7e-163 543.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dynamin_N PF00350.18 OAP55180.1 - 4.6e-06 26.5 0.0 9.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 OAP55180.1 - 0.0023 17.8 0.0 0.042 13.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAP55180.1 - 0.0056 15.8 0.0 0.048 12.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAP55180.1 - 0.011 15.6 0.1 0.054 13.4 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 OAP55180.1 - 0.015 15.6 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.11 OAP55180.1 - 0.028 13.5 0.1 0.27 10.3 0.0 2.1 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.1 OAP55180.1 - 0.044 13.9 0.1 0.97 9.5 0.0 3.0 3 1 1 4 4 4 0 AAA domain Ank PF00023.25 OAP55181.1 - 4.4e-92 297.6 5.8 2.6e-06 26.9 0.0 15.2 15 0 0 15 15 15 15 Ankyrin repeat Ank_2 PF12796.2 OAP55181.1 - 1.9e-91 300.5 0.5 1.9e-13 50.5 0.0 7.1 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP55181.1 - 2.4e-76 250.8 1.9 1.1e-10 41.6 0.0 12.7 3 3 10 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP55181.1 - 2.1e-67 221.6 2.8 1.7e-08 34.4 0.0 11.8 3 3 10 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP55181.1 - 8.9e-67 214.3 0.0 5.4e-05 23.0 0.0 15.2 15 0 0 15 15 15 13 Ankyrin repeat Shigella_OspC PF06128.6 OAP55181.1 - 2e-07 30.8 0.1 2.6 7.4 0.0 6.8 3 2 4 8 8 8 2 Shigella flexneri OspC protein DUF4646 PF15496.1 OAP55181.1 - 0.0041 17.1 0.1 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4646) Sugar_tr PF00083.19 OAP55182.1 - 1.6e-82 277.5 29.1 1.8e-82 277.3 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55182.1 - 2.4e-20 72.5 38.4 6.8e-14 51.3 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 OAP55182.1 - 0.15 11.5 0.6 0.27 10.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) DUF2530 PF10745.4 OAP55182.1 - 0.61 10.0 5.6 0.34 10.9 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Aldedh PF00171.17 OAP55183.1 - 4.5e-151 503.3 0.1 5.1e-151 503.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RuvA_C PF07499.8 OAP55183.1 - 0.79 9.9 3.4 1.7 8.8 1.3 2.3 2 0 0 2 2 2 0 RuvA, C-terminal domain TPP_enzyme_N PF02776.13 OAP55184.1 - 6.7e-36 123.3 0.0 3e-33 114.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP55184.1 - 7.5e-22 77.5 0.0 1.3e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 OAP55184.1 - 2.8e-14 52.9 0.0 5.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fungal_trans PF04082.13 OAP55185.1 - 8.2e-35 119.9 0.2 1.5e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55185.1 - 7.9e-08 32.0 8.8 1.5e-07 31.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 OAP55186.1 - 2.1e-171 570.3 0.3 2.7e-171 569.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pyr_redox_3 PF13738.1 OAP55187.1 - 6.8e-28 98.1 0.0 1e-27 97.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP55187.1 - 7.3e-17 60.7 0.0 1.7e-16 59.5 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP55187.1 - 3.4e-10 39.3 0.1 3.4e-08 32.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP55187.1 - 1.5e-08 34.5 0.3 3e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP55187.1 - 1.2e-06 28.5 0.0 2.3e-05 24.4 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP55187.1 - 0.00078 18.6 0.4 0.0018 17.4 0.0 1.8 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 OAP55187.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 OAP55187.1 - 0.0016 17.6 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 OAP55187.1 - 0.0061 16.3 1.0 0.32 10.7 0.1 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 OAP55187.1 - 0.0087 14.9 0.0 0.02 13.8 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 OAP55187.1 - 0.0088 16.1 0.0 0.25 11.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAP55187.1 - 0.086 13.1 0.0 0.67 10.2 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 OAP55187.1 - 0.11 12.9 0.2 15 6.0 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 OAP55187.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.14 OAP55187.1 - 0.22 10.5 2.2 1.5 7.7 0.3 2.7 3 1 1 4 4 4 0 FAD binding domain Sugar_tr PF00083.19 OAP55188.1 - 8.5e-79 265.2 23.3 9.8e-79 265.0 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55188.1 - 5.5e-23 81.2 47.7 6.3e-22 77.7 14.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM60A PF15396.1 OAP55188.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A 4HBT PF03061.17 OAP55189.1 - 2.6e-07 30.6 0.0 4.9e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily MARVEL PF01284.18 OAP55190.1 - 2.8e-10 40.1 12.9 3.7e-10 39.7 9.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Glucan_synthase PF02364.10 OAP55190.1 - 0.32 8.8 1.3 0.31 8.8 0.9 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component MIP PF00230.15 OAP55191.1 - 2.4e-46 158.0 13.0 3.1e-46 157.6 9.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans PF04082.13 OAP55192.1 - 5.1e-14 51.7 0.0 1.1e-13 50.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain SPACA7 PF15307.1 OAP55192.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 Acyl-CoA_ox_N PF14749.1 OAP55193.1 - 3.2e-20 72.7 0.7 5.7e-20 71.8 0.5 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACOX PF01756.14 OAP55193.1 - 3.2e-09 36.4 0.1 6e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 OAP55193.1 - 3.6e-09 36.0 0.3 1.2e-08 34.3 0.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 OAP55193.1 - 5.6e-05 23.2 0.1 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3717 PF12512.3 OAP55193.1 - 0.11 12.2 0.2 0.58 9.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3717) ECH PF00378.15 OAP55194.1 - 3.9e-27 94.9 0.0 4.5e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding PF00501.23 OAP55195.1 - 1.5e-52 178.4 0.0 2.1e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP55195.1 - 9.2e-13 48.9 0.1 3.1e-12 47.2 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cas_VVA1548 PF09652.5 OAP55195.1 - 0.14 12.1 0.0 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) MFS_1 PF07690.11 OAP55196.1 - 5.7e-29 100.9 28.6 5.7e-29 100.9 19.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ACOX PF01756.14 OAP55197.1 - 1.2e-34 119.3 0.1 2.6e-34 118.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 OAP55197.1 - 6.9e-22 78.0 0.3 1.7e-21 76.7 0.2 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAP55197.1 - 2e-08 33.5 0.4 6.2e-08 32.0 0.3 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 OAP55197.1 - 0.0032 17.5 0.2 0.42 10.7 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Aconitase PF00330.15 OAP55199.1 - 2.9e-57 194.1 0.0 1.3e-38 132.6 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAP55199.1 - 3e-19 69.4 0.0 5.4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Sugar_tr PF00083.19 OAP55200.1 - 1.7e-85 287.3 21.1 1.9e-85 287.1 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55200.1 - 1.3e-27 96.4 49.3 1.9e-25 89.3 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 OAP55200.1 - 1.8e-05 23.6 3.0 0.017 13.8 0.1 2.3 2 0 0 2 2 2 2 BT1 family TRI12 PF06609.8 OAP55200.1 - 0.00044 18.5 0.2 0.00044 18.5 0.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 OAP55201.1 - 7e-13 48.0 0.2 2.3e-12 46.3 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP55201.1 - 2.1e-06 27.7 14.9 2.2e-06 27.6 2.6 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP55201.1 - 2.2e-06 27.6 9.5 0.00063 19.9 1.7 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP55201.1 - 0.00027 21.0 8.6 0.00033 20.7 1.9 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-LYAR PF08790.6 OAP55201.1 - 5.2 6.8 7.0 22 4.8 1.3 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger TPR_11 PF13414.1 OAP55202.1 - 1.6e-12 46.8 6.4 2.1e-06 27.2 0.1 5.1 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 OAP55202.1 - 5.8e-10 38.3 11.4 0.00049 19.8 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAP55202.1 - 9e-08 31.4 1.5 0.013 15.1 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP55202.1 - 4.7e-05 23.6 7.8 0.057 13.7 0.0 5.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAP55202.1 - 8.9e-05 22.0 0.1 0.49 10.2 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP55202.1 - 0.00091 19.8 25.6 0.018 15.6 0.3 7.4 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAP55202.1 - 0.0022 18.0 4.3 12 6.3 0.0 6.5 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAP55202.1 - 0.014 15.3 14.4 5 7.1 0.4 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP55202.1 - 1.3 9.8 23.7 11 6.9 0.1 8.1 9 2 2 11 11 11 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAP55202.1 - 1.4 9.5 14.7 4.3 8.0 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 OAP55204.1 - 1.7e-16 60.7 0.1 5.4e-16 59.1 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP55204.1 - 8e-06 25.5 0.0 2.8e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP55204.1 - 0.0089 15.7 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAP55204.1 - 0.092 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Sugar_tr PF00083.19 OAP55206.1 - 1.3e-79 267.9 21.5 1.5e-79 267.7 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55206.1 - 8.6e-25 87.1 38.0 1.4e-19 70.0 8.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 OAP55206.1 - 0.022 13.5 8.3 0.046 12.4 5.8 1.5 1 0 0 1 1 1 0 PUCC protein FA_desaturase PF00487.19 OAP55206.1 - 2.3 7.6 16.5 2.2 7.6 0.7 3.5 3 0 0 3 3 3 0 Fatty acid desaturase MFS_1 PF07690.11 OAP55207.1 - 4.5e-37 127.5 41.3 4.5e-37 127.5 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP55207.1 - 3.4e-12 45.6 12.3 3.4e-12 45.6 8.6 3.3 1 1 0 2 2 2 1 Sugar (and other) transporter CN_hydrolase PF00795.17 OAP55208.1 - 7e-25 87.4 0.0 1.2e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ADH_zinc_N PF00107.21 OAP55209.1 - 2.7e-29 101.3 0.3 4.5e-29 100.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP55209.1 - 3.4e-18 65.3 0.3 7e-18 64.3 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP55209.1 - 0.0043 17.9 0.2 0.0093 16.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_like PF13242.1 OAP55209.1 - 0.1 12.2 0.1 15 5.4 0.1 2.5 2 0 0 2 2 2 0 HAD-hyrolase-like Glyco_trans_2_3 PF13632.1 OAP55210.1 - 8.1e-46 156.1 3.0 1.8e-45 155.0 2.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 OAP55210.1 - 0.00045 19.9 0.1 0.0031 17.2 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAP55210.1 - 0.00077 19.3 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAP55210.1 - 0.029 13.6 0.0 0.064 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 OAP55211.1 - 1.6e-21 76.4 0.2 4.7e-21 74.9 0.1 1.7 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 Arabinose_trans PF04602.7 OAP55211.1 - 0.28 9.3 0.6 0.98 7.5 0.0 1.8 2 0 0 2 2 2 0 Mycobacterial cell wall arabinan synthesis protein Citrate_synt PF00285.16 OAP55212.1 - 6.9e-97 324.3 0.0 8.2e-97 324.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ICL PF00463.16 OAP55213.1 - 1.7e-190 633.7 0.0 1.9e-190 633.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 OAP55213.1 - 5.4e-09 35.6 0.1 1.1e-08 34.5 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 OAP55213.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain ABC_tran PF00005.22 OAP55214.1 - 1e-48 165.1 0.1 2.3e-26 92.7 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAP55214.1 - 1.9e-15 57.6 0.9 0.0034 17.4 0.0 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 OAP55214.1 - 7.6e-12 44.9 0.1 0.0024 17.1 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAP55214.1 - 1.5e-07 31.9 0.1 0.002 18.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP55214.1 - 2e-07 30.4 0.4 0.01 15.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAP55214.1 - 6.8e-07 28.6 0.1 0.002 17.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 OAP55214.1 - 8.2e-07 28.9 0.0 0.0064 16.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 OAP55214.1 - 1.8e-06 27.3 0.1 0.1 11.6 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 OAP55214.1 - 1.8e-06 28.7 0.0 0.035 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 OAP55214.1 - 2.1e-06 28.1 0.0 0.0054 17.2 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein Chromo PF00385.19 OAP55214.1 - 1.1e-05 24.9 0.2 2.5e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SbcCD_C PF13558.1 OAP55214.1 - 2.9e-05 23.8 0.0 0.53 10.2 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 OAP55214.1 - 4.3e-05 23.6 0.1 0.24 11.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain CLASP_N PF12348.3 OAP55214.1 - 9e-05 21.9 0.0 0.0073 15.6 0.0 2.6 2 0 0 2 2 2 1 CLASP N terminal AAA_10 PF12846.2 OAP55214.1 - 0.00014 21.4 1.5 1 8.7 0.1 3.8 4 0 0 4 4 4 2 AAA-like domain AAA_28 PF13521.1 OAP55214.1 - 0.00017 21.6 0.0 0.014 15.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 OAP55214.1 - 0.00022 21.1 1.0 0.1 12.4 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF87 NACHT PF05729.7 OAP55214.1 - 0.00028 20.6 1.1 0.44 10.1 0.0 3.6 4 0 0 4 4 3 1 NACHT domain MobB PF03205.9 OAP55214.1 - 0.0004 20.0 0.5 1.1 8.9 0.1 3.4 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 OAP55214.1 - 0.00052 20.3 0.2 0.14 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 OAP55214.1 - 0.00067 18.5 0.5 0.18 10.5 0.1 2.5 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 OAP55214.1 - 0.0014 18.4 0.0 0.098 12.4 0.0 3.0 2 1 0 3 3 3 1 Dynamin family AAA_33 PF13671.1 OAP55214.1 - 0.0022 17.8 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAP55214.1 - 0.0023 17.4 0.2 0.49 9.8 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_13 PF13166.1 OAP55214.1 - 0.0034 15.9 0.0 1.3 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF3584 PF12128.3 OAP55214.1 - 0.0061 13.9 1.3 0.51 7.5 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) RNA_helicase PF00910.17 OAP55214.1 - 0.0061 16.7 0.1 4.6 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 OAP55214.1 - 0.0089 15.9 0.0 4.5 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 OAP55214.1 - 0.012 14.6 0.4 0.35 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 OAP55214.1 - 0.013 15.0 0.0 0.67 9.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 OAP55214.1 - 0.013 15.7 2.3 1.5 9.1 0.4 3.8 1 1 3 4 4 4 0 HEAT repeats HEAT PF02985.17 OAP55214.1 - 0.014 15.4 0.0 70 3.9 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat AAA_25 PF13481.1 OAP55214.1 - 0.014 14.7 0.0 8.7 5.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 OAP55214.1 - 0.016 14.8 0.3 6.9 6.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 OAP55214.1 - 0.029 14.3 0.2 3.3 7.6 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.7 OAP55214.1 - 0.032 13.3 0.4 5.8 5.9 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA PF00004.24 OAP55214.1 - 0.048 13.8 0.0 9.2 6.4 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 OAP55214.1 - 0.062 12.7 0.2 12 5.3 0.0 3.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SR-25 PF10500.4 OAP55214.1 - 0.075 12.5 4.0 0.17 11.3 2.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Septin PF00735.13 OAP55214.1 - 0.084 11.8 0.0 4.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Septin Ala_racemase_N PF01168.15 OAP55215.1 - 8.5e-36 123.5 0.5 2.6e-34 118.7 0.3 2.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 OAP55216.1 - 2.2e-126 422.2 7.5 2.6e-126 422.0 5.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 OAP55216.1 - 9.6e-42 141.5 0.0 2.6e-41 140.1 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 OAP55216.1 - 5.9e-20 71.7 0.0 1.1e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain ISN1 PF06437.6 OAP55217.1 - 3.1e-146 487.2 0.0 3.5e-146 487.1 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase ADH_N PF08240.7 OAP55218.1 - 2.4e-08 33.7 0.0 5.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP55218.1 - 2.4e-06 27.0 0.5 1.2e-05 24.8 0.4 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 OAP55218.1 - 0.045 13.6 0.6 0.089 12.7 0.4 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 OAP55218.1 - 0.051 13.5 0.2 0.14 12.1 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 OAP55218.1 - 0.14 11.3 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Nol1_Nop2_Fmu PF01189.12 OAP55218.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 NOL1/NOP2/sun family Fungal_trans PF04082.13 OAP55219.1 - 6.6e-11 41.5 0.0 1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain IFT57 PF10498.4 OAP55219.1 - 0.054 12.2 0.3 0.091 11.4 0.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4378 PF14309.1 OAP55219.1 - 0.093 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Med17 PF10156.4 OAP55220.1 - 1.4e-87 293.9 0.0 1.9e-87 293.4 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 OAP55221.1 - 1.1e-167 556.0 0.3 5.8e-121 402.7 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 OAP55221.1 - 0.097 12.2 0.2 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif NAD_kinase PF01513.16 OAP55221.1 - 0.11 11.3 0.1 0.33 9.6 0.0 1.7 2 0 0 2 2 2 0 ATP-NAD kinase Sugar_tr PF00083.19 OAP55223.1 - 2.3e-37 128.6 18.6 2.2e-25 89.1 1.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP55223.1 - 1.7e-22 79.6 23.5 2.6e-22 79.0 14.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4516 PF14990.1 OAP55223.1 - 0.032 13.7 0.0 0.11 12.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) zf-C2H2_4 PF13894.1 OAP55225.1 - 3.3 8.2 8.9 13 6.3 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger efThoc1 PF11957.3 OAP55226.1 - 2.5e-142 474.8 0.1 3.2e-142 474.4 0.1 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 OAP55227.1 - 9.9e-25 87.0 0.0 1.7e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAP55227.1 - 6.8e-24 84.7 0.0 1.3e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP55227.1 - 4.2e-10 39.2 0.1 3.2e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 OAP55227.1 - 1.9e-05 24.3 0.0 0.0006 19.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 OAP55227.1 - 0.00098 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 OAP55227.1 - 0.0047 16.2 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 OAP55227.1 - 0.012 15.7 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAP55227.1 - 0.015 15.3 0.1 0.063 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 OAP55227.1 - 0.016 15.3 0.0 0.05 13.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 OAP55227.1 - 0.02 14.3 0.0 0.058 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 OAP55227.1 - 0.033 13.6 0.1 0.22 11.0 0.0 2.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 OAP55227.1 - 0.039 13.0 0.0 0.092 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 OAP55227.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 OAP55227.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 OAP55227.1 - 0.14 11.1 0.2 0.44 9.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 OAP55227.1 - 0.19 10.5 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Adeno_IVa2 PF02456.10 OAP55227.1 - 0.46 9.0 0.6 15 4.0 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein GMC_oxred_N PF00732.14 OAP55228.1 - 2.8e-63 213.8 0.0 3.9e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP55228.1 - 1.9e-30 106.0 0.0 3.5e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 OAP55228.1 - 2.5e-05 23.3 0.0 6.2e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 OAP55228.1 - 7.3e-05 21.8 0.7 0.0051 15.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP55228.1 - 0.00028 19.8 0.6 0.0089 14.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP55228.1 - 0.0004 20.3 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP55228.1 - 0.0014 17.7 0.1 0.0078 15.3 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 OAP55228.1 - 0.012 15.5 0.1 0.033 14.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 OAP55228.1 - 0.024 13.2 0.1 0.034 12.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Translin PF01997.11 OAP55231.1 - 2.7e-46 157.6 0.1 3.4e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 Translin family HR1 PF02185.11 OAP55231.1 - 0.044 13.5 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Hr1 repeat MMR_HSR1_C PF08438.5 OAP55234.1 - 8.8e-32 109.5 0.0 1.5e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 OAP55234.1 - 1.5e-18 66.8 0.0 3.8e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP55234.1 - 8.7e-09 34.8 0.0 1.7e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 OAP55234.1 - 0.0057 16.1 0.0 1.6 8.1 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 OAP55234.1 - 0.0087 15.9 0.1 4.7 7.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAP55234.1 - 0.032 14.5 0.1 3.1 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 OAP55234.1 - 0.05 13.4 1.4 0.16 11.8 0.3 2.2 3 0 0 3 3 3 0 Dynamin family KTI12 PF08433.5 OAP55234.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 adh_short PF00106.20 OAP55235.1 - 6.2e-64 214.9 8.5 2e-32 112.4 0.7 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAP55235.1 - 2.6e-33 115.1 3.4 4.1e-16 59.1 0.2 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 OAP55235.1 - 3.4e-24 84.5 0.0 7.1e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAP55235.1 - 3.4e-11 43.0 0.0 8.2e-10 38.5 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Fungal_trans PF04082.13 OAP55236.1 - 1e-42 145.8 3.4 1.6e-42 145.2 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55236.1 - 4.7e-08 32.7 14.7 8.1e-08 32.0 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.7 OAP55236.1 - 0.14 12.4 0.7 14 5.9 0.1 2.3 2 0 0 2 2 2 0 Striatin family AKNA PF12443.3 OAP55236.1 - 0.18 11.8 4.1 3.2 7.8 0.1 3.0 2 1 1 3 3 3 0 AT-hook-containing transcription factor SET PF00856.23 OAP55237.1 - 1.2e-05 25.6 0.0 2.7e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 SET domain Glyco_hydro_2_C PF02836.12 OAP55238.1 - 3.6e-104 347.8 0.0 5e-104 347.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 OAP55238.1 - 4.2e-49 166.3 0.0 1.1e-48 165.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 OAP55238.1 - 2e-39 135.2 0.6 1.9e-29 102.5 0.0 3.2 2 1 0 2 2 2 2 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 OAP55238.1 - 2e-13 50.7 0.0 5.6e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 SUN PF03856.8 OAP55239.1 - 4.2e-89 298.1 16.4 6.6e-89 297.4 11.4 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF202 PF02656.10 OAP55240.1 - 3.1e-24 84.9 2.7 3.1e-24 84.9 1.9 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF202) MFS_1 PF07690.11 OAP55241.1 - 6.7e-22 77.6 30.6 6.7e-22 77.6 21.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 OAP55242.1 - 6.6e-13 48.4 0.7 1.3e-11 44.1 0.5 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP55242.1 - 0.00085 19.3 0.1 0.0025 17.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP55242.1 - 0.0023 16.9 0.2 0.18 10.6 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 OAP55242.1 - 0.0066 15.3 1.4 0.18 10.6 0.1 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP55242.1 - 2.9 6.6 7.4 0.36 9.6 0.6 2.3 2 1 0 3 3 3 0 FAD binding domain FMO-like PF00743.14 OAP55243.1 - 4.6e-28 97.7 0.0 6.1e-10 37.9 0.0 3.3 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAP55243.1 - 8.5e-21 74.9 0.0 1.6e-19 70.8 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP55243.1 - 1.8e-11 43.5 0.3 7.4e-09 34.9 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP55243.1 - 7.8e-07 29.1 0.0 0.00036 20.4 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP55243.1 - 6.3e-06 26.1 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP55243.1 - 7.1e-06 25.8 0.0 0.0093 15.7 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Amino_oxidase PF01593.19 OAP55243.1 - 0.00089 18.4 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 OAP55243.1 - 0.0046 16.0 0.1 0.01 14.9 0.0 1.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 OAP55243.1 - 0.006 15.5 0.0 0.61 8.9 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP55243.1 - 0.026 14.9 0.7 1.1 9.7 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PTPA PF03095.10 OAP55244.1 - 4.7e-111 370.7 0.0 5.6e-111 370.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_transf_8 PF01501.15 OAP55247.1 - 4.3e-23 81.9 0.0 5.6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.22 OAP55248.1 - 2.3e-56 187.4 0.5 1.1e-19 69.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNase_PH PF01138.16 OAP55249.1 - 1.5e-10 41.4 0.0 3.2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ATPgrasp_Ter PF15632.1 OAP55249.1 - 0.038 12.7 0.0 0.12 11.0 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon NAD_kinase PF01513.16 OAP55250.1 - 3.4e-70 236.0 0.0 4.4e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DEAD PF00270.24 OAP55252.1 - 2e-40 138.0 0.2 4.8e-40 136.8 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP55252.1 - 4.1e-29 100.2 0.1 8.5e-29 99.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 OAP55252.1 - 0.00015 21.4 0.1 0.00034 20.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 OAP55252.1 - 0.0028 17.5 0.1 0.0054 16.5 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 OAP55252.1 - 0.014 14.9 0.3 0.033 13.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 OAP55252.1 - 0.017 14.9 0.2 0.06 13.1 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 OAP55252.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.16 OAP55252.1 - 0.087 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.1 OAP55252.1 - 0.089 12.3 0.3 0.11 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAP55252.1 - 0.097 12.8 0.5 0.42 10.7 0.3 2.0 1 1 0 1 1 1 0 AAA domain p450 PF00067.17 OAP55253.1 - 1.1e-80 271.4 0.0 1.3e-80 271.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 OAP55254.1 - 1.1e-30 106.8 3.3 1.3e-30 106.4 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55254.1 - 2.2e-26 93.1 0.0 2.6e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55254.1 - 2.6e-13 50.0 0.5 4e-13 49.4 0.3 1.3 1 0 0 1 1 1 1 KR domain Peripla_BP_4 PF13407.1 OAP55254.1 - 0.0085 15.4 1.4 0.012 14.9 1.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Ldh_1_N PF00056.18 OAP55254.1 - 0.019 14.7 0.6 0.033 14.0 0.4 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 OAP55255.1 - 2.4e-23 83.1 0.0 3.2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP55255.1 - 1.4e-21 77.1 0.5 2e-21 76.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP55255.1 - 3.1e-07 30.2 0.2 4.8e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP55255.1 - 0.001 18.5 0.1 0.0039 16.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_26 PF13659.1 OAP55255.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 OAP55255.1 - 0.07 12.9 1.6 0.16 11.8 1.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_6 PF12697.2 OAP55256.1 - 1.1e-13 51.6 0.0 1.5e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55256.1 - 1.8e-13 50.5 0.0 3.7e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAP55256.1 - 4.8e-10 38.4 0.1 1.8e-06 26.6 0.0 3.0 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 OAP55256.1 - 2.1e-08 33.9 0.0 3.8e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 OAP55256.1 - 8.7e-07 28.3 0.1 3e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 OAP55256.1 - 1.6e-05 24.7 0.0 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 OAP55256.1 - 0.00024 20.4 0.0 0.059 12.6 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family PhoPQ_related PF10142.4 OAP55256.1 - 0.075 11.4 0.1 0.15 10.4 0.1 1.5 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein adh_short_C2 PF13561.1 OAP55257.1 - 1.5e-27 96.9 0.0 1.8e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP55257.1 - 1e-24 87.3 1.0 1.5e-24 86.7 0.4 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP55257.1 - 3.8e-06 26.7 0.1 7.1e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP55257.1 - 0.00043 19.7 0.0 0.001 18.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP55257.1 - 0.0045 16.7 0.4 0.0082 15.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 OAP55257.1 - 0.015 15.2 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding Fungal_trans PF04082.13 OAP55258.1 - 7.9e-15 54.4 1.9 7.9e-15 54.4 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 OAP55259.1 - 4.7e-30 104.6 0.2 6.4e-30 104.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55259.1 - 1.4e-26 93.7 0.0 1.7e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55259.1 - 7e-19 68.1 0.1 9.3e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 OAP55259.1 - 7.1e-07 28.2 0.3 1.1e-06 27.5 0.1 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 OAP55259.1 - 0.00092 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 OAP55259.1 - 0.0082 15.0 0.2 0.0099 14.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Oxidored_nitro PF00148.14 OAP55259.1 - 0.011 14.3 0.0 0.03 12.9 0.0 1.6 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AlaDh_PNT_C PF01262.16 OAP55259.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ACT PF01842.20 OAP55259.1 - 0.082 12.4 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 ACT domain TrkA_N PF02254.13 OAP55259.1 - 0.09 12.7 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.19 OAP55260.1 - 2.6e-87 293.2 27.3 3e-87 293.0 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55260.1 - 9.1e-21 73.9 46.2 2.3e-13 49.5 13.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 OAP55261.1 - 2.8e-29 102.6 0.1 4.1e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55261.1 - 3.7e-11 42.9 0.0 1.1e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP55261.1 - 3.7e-10 39.7 0.0 3.2e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAP55261.1 - 2.8e-08 33.4 0.0 4.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 OAP55261.1 - 0.023 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1057 PF06342.7 OAP55261.1 - 0.032 13.0 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) EHN PF06441.7 OAP55261.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus adh_short PF00106.20 OAP55262.1 - 7.4e-21 74.7 0.0 1.3e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55262.1 - 2.1e-08 34.2 0.0 3.7e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55262.1 - 4.5e-08 32.9 0.0 4.6e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 KR domain Eno-Rase_NADH_b PF12242.3 OAP55262.1 - 0.00048 19.8 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP55262.1 - 0.096 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B_3 PF13483.1 OAP55263.1 - 2.8e-05 23.8 0.0 5.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3818 PF12825.2 OAP55264.1 - 7e-40 136.7 5.5 2.9e-24 85.4 0.7 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 OAP55264.1 - 1.7e-22 79.5 0.0 4e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 PX-associated DUF89 PF01937.14 OAP55264.1 - 0.027 13.2 0.0 0.063 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF89 DUF3415 PF11895.3 OAP55264.1 - 0.034 14.0 0.5 0.089 12.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) Arrestin_N PF00339.24 OAP55265.1 - 2.6e-15 56.5 0.0 6.6e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 OAP55265.1 - 7.4e-15 55.2 0.0 2.1e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 OAP55265.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like WD40 PF00400.27 OAP55266.1 - 1.9e-20 71.8 10.5 2.6e-06 27.0 0.5 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 OAP55266.1 - 6.8e-05 22.6 0.0 0.0065 16.1 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 OAP55266.1 - 0.0004 18.3 0.0 0.00061 17.7 0.0 1.3 1 0 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.11 OAP55266.1 - 0.012 13.9 0.0 0.024 12.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.7 OAP55266.1 - 0.05 13.2 0.0 8.9 6.1 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cwf_Cwc_15 PF04889.7 OAP55267.1 - 0.01 15.5 1.1 0.011 15.4 0.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 OAP55267.1 - 0.048 13.1 2.7 0.068 12.6 1.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Pilt PF15453.1 OAP55267.1 - 0.082 12.5 1.1 0.092 12.4 0.7 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions BSP_II PF05432.6 OAP55267.1 - 0.73 9.0 8.8 1.3 8.2 6.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 OAP55267.1 - 1.9 7.6 4.7 2.5 7.2 3.2 1.1 1 0 0 1 1 1 0 NOA36 protein Endonuclease_NS PF01223.18 OAP55268.1 - 6.3e-57 192.5 0.0 9.7e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease FAP PF07174.6 OAP55268.1 - 8 5.6 20.4 1.8 7.7 11.5 1.7 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Zip PF02535.17 OAP55269.1 - 7.4e-28 97.4 13.3 5.1e-26 91.4 9.2 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter AAA PF00004.24 OAP55270.1 - 2.5e-17 63.3 0.0 4.4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAP55270.1 - 0.0028 18.4 0.6 0.21 12.4 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP55270.1 - 0.0051 16.9 0.1 0.23 11.5 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 OAP55270.1 - 0.0055 16.9 0.1 0.34 11.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAP55270.1 - 0.0056 15.7 0.0 0.0095 15.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAP55270.1 - 0.02 14.8 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 OAP55270.1 - 0.029 14.0 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zot PF05707.7 OAP55270.1 - 0.045 13.2 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 OAP55270.1 - 0.18 11.5 0.4 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain Rhabdo_glycop PF00974.13 OAP55271.1 - 1.6 6.8 14.4 1.8 6.7 10.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Pectate_lyase_3 PF12708.2 OAP55272.1 - 4.4e-68 229.7 18.3 4.5e-56 190.4 6.5 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 OAP55272.1 - 1.7e-05 24.1 0.7 0.0087 15.5 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase NosD PF05048.8 OAP55272.1 - 0.0087 15.2 3.2 0.017 14.2 2.2 1.5 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.1 OAP55272.1 - 0.022 14.5 7.0 0.029 14.1 3.4 2.2 1 1 0 1 1 1 0 Right handed beta helix region AMP-binding PF00501.23 OAP55274.1 - 6.5e-80 268.5 0.0 1.1e-79 267.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP55274.1 - 0.027 15.4 0.2 0.071 14.0 0.2 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Nop16 PF09420.5 OAP55274.1 - 0.081 13.0 2.3 0.42 10.6 0.1 3.0 3 1 0 3 3 3 0 Ribosome biogenesis protein Nop16 Methyltransf_16 PF10294.4 OAP55275.1 - 1.2e-15 57.4 0.4 2.5e-14 53.1 0.3 2.1 1 1 0 1 1 1 1 Putative methyltransferase IBN_N PF03810.14 OAP55276.1 - 6.7e-14 51.5 4.7 2.9e-12 46.3 0.0 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 OAP55276.1 - 3e-11 42.4 0.0 6.5e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Cse1 DUF2435 PF10363.4 OAP55276.1 - 0.00076 19.3 1.3 0.0042 16.9 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 OAP55276.1 - 0.0016 18.6 4.5 2.5 8.4 0.0 4.2 3 1 0 4 4 4 2 HEAT repeats Xpo1 PF08389.7 OAP55276.1 - 0.054 13.3 5.2 1.8 8.4 0.0 3.4 3 0 0 3 3 3 0 Exportin 1-like protein zf-RanBP PF00641.13 OAP55277.1 - 1.5e-19 68.8 9.7 6.5e-11 41.1 1.2 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 OAP55277.1 - 4.8e-08 32.5 0.0 8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 OAP55277.1 - 1.3e-07 32.0 0.0 2.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 OAP55277.1 - 1.5e-05 24.8 0.0 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 OAP55277.1 - 2.2 8.1 8.0 0.9 9.4 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon Oxidored_molyb PF00174.14 OAP55278.1 - 4.6e-48 162.8 0.0 6.5e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 OAP55278.1 - 2e-22 79.2 1.0 5.4e-22 77.8 0.1 2.0 2 1 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Peptidase_M20 PF01546.23 OAP55280.1 - 4.9e-23 81.6 0.0 6.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAP55280.1 - 0.0001 22.0 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 OAP55280.1 - 0.00018 21.2 0.0 0.00049 19.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 S10_plectin PF03501.10 OAP55281.1 - 4.7e-40 135.3 0.1 6.4e-40 134.9 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_S8e PF01201.17 OAP55282.1 - 1.5e-47 161.0 2.6 1.8e-47 160.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_60s PF00428.14 OAP55282.1 - 0.032 14.6 1.1 0.053 13.9 0.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein ADH_N PF08240.7 OAP55284.1 - 1.5e-35 121.2 0.9 1.5e-35 121.2 0.7 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP55284.1 - 1.4e-15 57.0 0.0 2.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP55284.1 - 0.0001 23.1 0.0 0.00018 22.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 OAP55284.1 - 0.026 13.5 0.2 0.042 12.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Gp_dh_N PF00044.19 OAP55284.1 - 0.035 14.0 0.0 0.088 12.7 0.0 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2318 PF10080.4 OAP55284.1 - 0.072 12.8 0.7 8.7 6.1 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) HECT PF00632.20 OAP55285.1 - 5.6e-76 255.7 0.0 8e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 OAP55285.1 - 0.079 12.6 0.7 0.17 11.6 0.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ITAM_Cys-rich PF10538.4 OAP55285.1 - 3.2 7.3 5.3 0.84 9.2 1.0 2.0 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif GMC_oxred_N PF00732.14 OAP55286.1 - 2.6e-47 161.3 0.0 3.6e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP55286.1 - 9e-34 116.8 0.0 1.8e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP55286.1 - 1.3e-05 24.3 0.2 0.018 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP55286.1 - 3.7e-05 22.8 0.1 6.9e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 OAP55286.1 - 0.00084 17.9 0.2 0.024 13.1 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 OAP55286.1 - 0.0016 17.3 0.3 0.085 11.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 OAP55286.1 - 0.0047 16.9 0.1 0.0047 16.9 0.0 2.5 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP55286.1 - 0.019 14.8 0.2 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP55286.1 - 0.045 13.5 0.2 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 OAP55286.1 - 0.047 12.5 0.2 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAP55286.1 - 0.048 13.7 0.1 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MMR_HSR1 PF01926.18 OAP55287.1 - 1.3e-06 28.3 0.0 4e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ADH_zinc_N_2 PF13602.1 OAP55288.1 - 8.5e-18 65.4 0.0 1.5e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP55288.1 - 9e-12 44.7 0.1 9.4e-10 38.2 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP55288.1 - 2.8e-11 43.0 0.1 5.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Herpes_UL6 PF01763.11 OAP55289.1 - 0.00088 17.5 0.3 0.00096 17.4 0.2 1.0 1 0 0 1 1 1 1 Herpesvirus UL6 like PspA_IM30 PF04012.7 OAP55289.1 - 0.011 15.0 2.3 0.014 14.7 1.6 1.1 1 0 0 1 1 1 0 PspA/IM30 family NEMO PF11577.3 OAP55289.1 - 0.017 14.8 1.8 0.029 14.1 1.2 1.3 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Striatin PF08232.7 OAP55289.1 - 0.037 14.3 2.6 0.049 13.9 1.8 1.1 1 0 0 1 1 1 0 Striatin family V_ATPase_I PF01496.14 OAP55289.1 - 0.086 10.6 0.6 0.088 10.6 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bromodomain PF00439.20 OAP55290.1 - 5e-14 51.9 0.0 2.5e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 Bromodomain PI-PLC-X PF00388.14 OAP55291.1 - 1.7e-59 199.4 0.0 2.9e-59 198.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 OAP55291.1 - 3.5e-38 130.1 0.2 8.2e-38 129.0 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 OAP55291.1 - 1.5e-05 24.9 0.0 0.00021 21.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 OAP55291.1 - 0.032 14.3 0.3 0.077 13.1 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair CATSPERB PF15149.1 OAP55291.1 - 0.04 12.1 0.0 0.071 11.2 0.0 1.3 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family EF-hand_1 PF00036.27 OAP55291.1 - 0.12 11.7 0.0 0.34 10.3 0.0 1.8 1 0 0 1 1 1 0 EF hand DUF3431 PF11913.3 OAP55292.1 - 3.5e-72 242.4 0.0 4.3e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) CopD PF05425.8 OAP55294.1 - 0.0025 18.0 0.5 0.011 15.9 0.0 2.3 3 0 0 3 3 3 1 Copper resistance protein D LRR_4 PF12799.2 OAP55295.1 - 0.00017 21.1 8.9 0.016 14.8 0.4 5.2 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 OAP55295.1 - 0.0028 17.5 13.3 11 6.3 0.0 7.3 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 OAP55295.1 - 0.36 11.0 14.6 93 3.6 0.0 7.7 7 2 1 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.1 OAP55295.1 - 0.55 10.0 9.1 0.81 9.4 1.1 4.0 2 1 2 4 4 4 0 Leucine rich repeat Ribosomal_L18p PF00861.17 OAP55296.1 - 1.4e-43 147.8 0.0 2.6e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 OAP55296.1 - 3.2e-33 114.1 8.9 3.2e-33 114.1 6.2 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Spc7 PF08317.6 OAP55297.1 - 1.6 7.3 8.1 0.3 9.7 3.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein adh_short PF00106.20 OAP55299.1 - 8.7e-20 71.2 0.0 1.3e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAP55299.1 - 5.1e-08 33.1 0.0 7.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAP55299.1 - 5.2e-08 32.7 0.0 8.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP55299.1 - 4.1e-06 26.4 0.0 5.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAP55299.1 - 0.085 12.6 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 OAP55299.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.17 OAP55300.1 - 7.2e-45 153.3 0.0 9.8e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 OAP55301.1 - 1.2e-70 238.5 0.1 6.3e-70 236.2 0.1 1.8 1 1 0 1 1 1 1 Amidase DUF3940 PF13076.1 OAP55301.1 - 0.082 12.4 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) Fungal_trans_2 PF11951.3 OAP55302.1 - 5e-13 48.4 0.7 9.5e-12 44.1 0.5 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP55304.1 - 1.3e-41 142.4 23.3 1.7e-41 142.1 16.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily EXS PF03124.9 OAP55304.1 - 0.047 12.7 7.0 0.015 14.3 1.4 2.5 2 2 0 2 2 2 0 EXS family DUF3753 PF12575.3 OAP55304.1 - 0.069 12.9 0.5 0.61 9.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) 2TM PF13239.1 OAP55304.1 - 0.42 10.7 2.4 10 6.2 0.4 2.9 2 0 0 2 2 2 0 2TM domain RPAP1_N PF08621.5 OAP55304.1 - 0.47 10.0 2.8 0.32 10.6 0.4 1.8 2 0 0 2 2 2 0 RPAP1-like, N-terminal DUF4231 PF14015.1 OAP55304.1 - 8.9 6.3 16.1 0.92 9.5 0.5 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF4231) EamA PF00892.15 OAP55304.1 - 9.7 6.2 20.5 0.57 10.2 1.8 3.4 4 0 0 4 4 4 0 EamA-like transporter family MFS_1 PF07690.11 OAP55305.1 - 1e-40 139.5 32.6 2.2e-40 138.4 22.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP55305.1 - 7.4e-18 64.3 24.2 1.2e-17 63.6 16.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 OAP55305.1 - 4.5e-07 28.4 1.0 4.5e-07 28.4 0.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 OAP55305.1 - 0.0021 16.1 1.2 1.3 6.9 0.6 3.7 4 0 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family ApbA_C PF08546.6 OAP55306.1 - 3.7e-28 98.0 0.1 6.6e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 OAP55306.1 - 8.4e-26 90.2 0.0 1.1e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 OAP55306.1 - 0.021 15.0 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 OAP55306.1 - 0.032 14.7 0.0 0.076 13.5 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.1 OAP55306.1 - 0.093 12.7 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding Abhydrolase_6 PF12697.2 OAP55307.1 - 1.6e-25 90.3 0.8 1.9e-25 90.0 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55307.1 - 1.1e-12 47.9 0.0 1.8e-12 47.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAP55307.1 - 0.00059 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 OAP55307.1 - 0.063 12.8 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein HMGL-like PF00682.14 OAP55308.1 - 5.2e-70 235.7 0.6 8.4e-70 235.0 0.4 1.3 1 0 0 1 1 1 1 HMGL-like Pyridoxal_deC PF00282.14 OAP55309.1 - 1.8e-20 72.7 0.0 2.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 OAP55309.1 - 8.5e-06 24.7 0.0 1.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 OAP55309.1 - 0.0018 17.4 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family TPR_12 PF13424.1 OAP55310.1 - 1.1e-07 31.6 0.2 0.00043 20.1 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Clr5 PF14420.1 OAP55310.1 - 1.2e-06 28.2 0.0 2.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_16 PF13432.1 OAP55310.1 - 0.00023 21.7 1.1 0.00023 21.7 0.8 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP55310.1 - 0.43 10.6 3.3 2.5 8.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF605 PF04652.11 OAP55310.1 - 3.7 6.8 15.8 1.1 8.6 7.2 2.2 2 0 0 2 2 2 0 Vta1 like Serglycin PF04360.7 OAP55310.1 - 6.9 6.3 7.8 0.12 12.1 0.3 1.8 2 0 0 2 2 2 0 Serglycin NTP_transferase PF00483.18 OAP55311.1 - 3.6e-48 164.0 0.0 8e-48 162.8 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 OAP55311.1 - 1.1e-12 46.7 7.6 9.5e-10 37.5 1.4 3.8 1 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 OAP55311.1 - 1.3e-10 41.6 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 OAP55311.1 - 1.8e-05 24.2 2.5 1.8e-05 24.2 1.7 3.1 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 OAP55311.1 - 0.0076 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase dTMP_synthase PF02593.9 OAP55311.1 - 0.019 14.3 0.1 1.1 8.6 0.0 2.1 1 1 1 2 2 2 0 Thymidylate synthase CTP_transf_3 PF02348.14 OAP55311.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase SRP40_C PF05022.7 OAP55313.1 - 2.2e-22 79.3 2.5 6.4e-22 77.8 1.8 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.6 OAP55313.1 - 0.00073 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 LisH Glycos_transf_1 PF00534.15 OAP55313.1 - 0.014 14.8 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Utp14 PF04615.8 OAP55313.1 - 0.85 7.7 39.5 1 7.4 27.4 1.2 1 0 0 1 1 1 0 Utp14 protein p450 PF00067.17 OAP55314.1 - 2.1e-60 204.5 0.0 2.9e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fasciclin PF02469.17 OAP55316.1 - 8.3e-22 77.5 4.6 1.8e-18 66.8 0.1 2.6 2 1 0 2 2 2 2 Fasciclin domain DASH_Ask1 PF08655.5 OAP55317.1 - 1.3e-32 111.3 0.1 2.3e-32 110.6 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 SBF2 PF12335.3 OAP55317.1 - 0.027 13.8 0.7 0.044 13.1 0.5 1.4 1 0 0 1 1 1 0 Myotubularin protein CDK5_activator PF03261.10 OAP55317.1 - 0.095 12.0 5.9 0.019 14.3 1.3 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Tox-GHH PF15636.1 OAP55318.1 - 3.3 7.4 8.4 8.5 6.0 3.4 2.8 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Chitin_synth_2 PF03142.10 OAP55319.1 - 5.5e-26 91.0 1.1 4.2e-23 81.5 0.5 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAP55319.1 - 3e-19 69.5 6.0 3e-19 69.5 4.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAP55319.1 - 2.1e-16 60.4 0.0 3.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAP55319.1 - 0.0073 15.6 0.5 0.31 10.3 0.2 2.9 2 1 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAP55319.1 - 0.033 13.8 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.15 OAP55320.1 - 6.8e-161 536.1 2.5 6.8e-161 536.1 1.7 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 OAP55320.1 - 1.7e-09 36.7 0.0 4.4e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 OAP55320.1 - 1.7e-05 24.6 0.8 0.29 10.9 0.0 4.0 2 2 0 2 2 2 2 Cell division protein FtsA Thiolase_N PF00108.18 OAP55321.1 - 1.1e-67 227.8 0.1 2.1e-67 226.9 0.1 1.5 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAP55321.1 - 3.3e-41 139.5 0.4 6.8e-41 138.5 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAP55321.1 - 0.0091 15.4 1.1 0.018 14.4 0.4 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 OAP55321.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SUKH-3 PF14433.1 OAP55321.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 SUKH-3 immunity protein PAC2 PF09754.4 OAP55322.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 PAC2 family AAA PF00004.24 OAP55323.1 - 2.9e-17 63.0 0.0 2.6e-16 60.0 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 OAP55323.1 - 6.4e-05 22.6 0.1 0.00032 20.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 OAP55323.1 - 0.0023 17.6 0.7 0.03 14.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 OAP55323.1 - 0.0032 17.7 0.2 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zot PF05707.7 OAP55323.1 - 0.007 15.8 0.2 0.14 11.5 0.1 2.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 OAP55323.1 - 0.0088 16.1 0.7 0.12 12.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 OAP55323.1 - 0.0093 15.4 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 OAP55323.1 - 0.012 15.6 0.1 0.038 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 OAP55323.1 - 0.014 16.2 1.5 0.049 14.4 0.1 2.8 3 1 0 3 3 2 0 AAA domain AAA_28 PF13521.1 OAP55323.1 - 0.016 15.1 2.3 0.043 13.7 0.4 2.6 2 1 1 3 3 3 0 AAA domain cobW PF02492.14 OAP55323.1 - 0.063 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 OAP55323.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 OAP55323.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Torsin KaiC PF06745.8 OAP55323.1 - 0.15 11.1 0.3 0.34 10.0 0.2 1.5 1 0 0 1 1 1 0 KaiC adh_short PF00106.20 OAP55324.1 - 5.4e-34 117.5 2.5 6.7e-34 117.2 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55324.1 - 2.4e-30 106.1 0.6 2.7e-30 105.9 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55324.1 - 2.8e-14 53.1 1.5 3.7e-14 52.7 1.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAP55324.1 - 4e-05 23.3 0.3 7.3e-05 22.4 0.1 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_31 PF13614.1 OAP55324.1 - 0.0025 17.7 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Epimerase PF01370.16 OAP55324.1 - 0.0035 16.7 1.3 0.011 15.2 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP55324.1 - 0.0046 16.7 0.0 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 OAP55324.1 - 0.005 15.7 0.2 0.0061 15.4 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 OAP55324.1 - 0.0056 16.0 0.1 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Semialdhyde_dh PF01118.19 OAP55324.1 - 0.0057 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CW_binding_2 PF04122.7 OAP55324.1 - 0.016 15.3 1.0 0.03 14.5 0.0 1.9 3 0 0 3 3 1 0 Putative cell wall binding repeat 2 NUDIX_2 PF13869.1 OAP55324.1 - 0.025 13.9 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Methyltransf_26 PF13659.1 OAP55324.1 - 0.042 13.8 0.1 0.071 13.1 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain tRNA_anti-like PF12869.2 OAP55324.1 - 0.047 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 tRNA_anti-like Methyltransf_18 PF12847.2 OAP55324.1 - 0.048 14.2 0.0 0.083 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 OAP55324.1 - 0.049 13.1 0.1 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ldh_1_N PF00056.18 OAP55324.1 - 0.065 13.0 0.4 0.16 11.8 0.2 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 OAP55324.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-bind_6 PF13921.1 OAP55325.1 - 6.2e-29 99.8 5.3 1.2e-12 47.7 0.2 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAP55325.1 - 1.9e-23 82.2 14.3 3.1e-09 36.7 0.2 4.2 3 1 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 OAP55325.1 - 0.0023 18.0 5.1 0.25 11.5 0.1 3.6 3 1 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 OAP55325.1 - 0.035 13.9 5.4 0.91 9.4 0.0 3.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SRA1 PF07304.6 OAP55325.1 - 4.2 7.0 6.7 2.4 7.8 0.0 2.8 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) ketoacyl-synt PF00109.21 OAP55326.1 - 5.9e-78 261.8 0.0 1.1e-77 261.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 OAP55326.1 - 2.9e-52 177.9 0.0 4.7e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 OAP55326.1 - 9.9e-35 118.9 0.1 3.1e-34 117.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 OAP55326.1 - 8.6e-26 91.5 0.1 2.2e-24 86.9 0.0 2.7 3 0 0 3 3 3 1 Thioesterase domain PP-binding PF00550.20 OAP55326.1 - 3.1e-24 85.0 5.6 4.1e-11 42.9 0.1 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 OAP55326.1 - 2.5e-19 69.5 0.0 7.3e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 OAP55326.1 - 1.2e-07 31.9 0.0 0.00051 19.9 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55326.1 - 3.5e-05 23.5 0.0 0.073 12.8 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 OAP55326.1 - 5.3e-05 22.3 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 OAP55326.1 - 0.36 10.1 0.0 0.75 9.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Telomere_Sde2_2 PF13297.1 OAP55326.1 - 2.2 7.5 4.8 1.3 8.3 0.1 2.9 4 0 0 4 4 4 0 Telomere stability C-terminal FAD_binding_3 PF01494.14 OAP55327.1 - 2.7e-19 69.4 0.1 7.1e-19 68.0 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 OAP55327.1 - 9.3e-06 24.9 0.1 0.05 12.6 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 OAP55327.1 - 2.3e-05 23.4 1.2 0.00028 19.9 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP55327.1 - 3.9e-05 23.5 1.8 7.4e-05 22.6 0.5 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP55327.1 - 0.00059 18.8 0.0 0.00086 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 OAP55327.1 - 0.0013 18.5 0.2 0.14 11.9 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAP55327.1 - 0.0016 17.3 0.2 0.02 13.7 0.1 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein SE PF08491.5 OAP55327.1 - 0.0033 16.2 0.0 0.0071 15.1 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 OAP55327.1 - 0.005 16.7 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP55327.1 - 0.0092 16.3 0.2 0.07 13.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP55327.1 - 0.12 10.8 0.4 0.44 8.9 0.2 1.8 1 1 0 1 1 1 0 HI0933-like protein F420_oxidored PF03807.12 OAP55327.1 - 0.21 12.0 0.6 0.59 10.5 0.4 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_4 PF01565.18 OAP55328.1 - 1.5e-17 63.3 1.8 2.5e-17 62.6 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAP55328.1 - 1.8e-12 46.9 0.4 4.6e-12 45.6 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Scytalone_dh PF02982.9 OAP55329.1 - 2.5e-48 163.6 0.5 2.9e-48 163.4 0.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_3 PF13474.1 OAP55329.1 - 0.052 13.5 1.6 0.096 12.7 1.1 1.6 1 1 0 1 1 1 0 SnoaL-like domain adh_short PF00106.20 OAP55330.1 - 1.5e-37 129.0 2.2 5.1e-37 127.3 1.1 1.8 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55330.1 - 8e-23 81.4 0.0 9.9e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55330.1 - 8.8e-23 80.8 0.6 1.3e-22 80.3 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP55330.1 - 5e-05 22.8 0.2 8.1e-05 22.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 OAP55330.1 - 0.012 15.3 0.0 0.078 12.6 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAP55330.1 - 0.065 12.8 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.14 OAP55330.1 - 0.087 11.8 0.4 1.5 7.8 0.1 2.1 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 OAP55330.1 - 0.095 11.8 0.0 0.22 10.6 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.8 OAP55331.1 - 4.7e-57 192.9 0.0 6e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP55331.1 - 3.9e-16 59.5 0.0 6.4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP55331.1 - 4.8e-08 32.0 0.0 7.4e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ank_2 PF12796.2 OAP55332.1 - 5.7e-100 327.8 0.0 5.1e-19 68.4 0.0 6.5 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 OAP55332.1 - 7.5e-83 268.4 0.0 1.5e-08 34.0 0.0 10.4 11 0 0 11 11 10 9 Ankyrin repeat Ank_5 PF13857.1 OAP55332.1 - 6.4e-77 251.8 2.1 1.1e-11 44.5 0.0 9.3 3 1 8 11 11 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP55332.1 - 3.7e-60 193.8 0.0 2.6e-05 24.0 0.0 11.0 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 OAP55332.1 - 1.1e-57 191.4 0.1 2.6e-11 43.7 0.0 7.7 3 2 4 8 8 8 7 Ankyrin repeats (many copies) HET PF06985.6 OAP55332.1 - 1.4e-21 77.0 6.2 8.9e-20 71.2 4.3 2.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.1 OAP55332.1 - 8.6e-06 25.8 0.0 5e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Shigella_OspC PF06128.6 OAP55332.1 - 0.00012 21.6 0.0 25 4.2 0.0 5.5 1 1 6 7 7 7 0 Shigella flexneri OspC protein NACHT PF05729.7 OAP55332.1 - 0.00014 21.5 0.0 0.00034 20.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 OAP55332.1 - 0.0026 17.8 0.0 0.008 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP55332.1 - 0.026 15.3 0.1 0.26 12.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain UBA PF00627.26 OAP55332.1 - 0.088 12.6 5.2 38 4.2 0.0 6.1 9 0 0 9 9 7 0 UBA/TS-N domain DUF4235 PF14019.1 OAP55332.1 - 0.18 11.7 0.0 30 4.5 0.0 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4235) Zn_clus PF00172.13 OAP55334.1 - 4.1e-10 39.3 9.6 9.3e-10 38.2 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.1 OAP55334.1 - 0.17 11.5 7.0 2.1 8.0 2.6 2.5 2 0 0 2 2 2 0 Cytochrome c7 adh_short PF00106.20 OAP55335.1 - 3.1e-24 85.7 0.0 3.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55335.1 - 5.7e-14 52.4 0.0 7.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55335.1 - 2e-09 37.3 0.0 2.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP55335.1 - 0.0021 17.8 0.7 0.0049 16.6 0.5 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 OAP55335.1 - 0.078 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Arylsulfotran_2 PF14269.1 OAP55336.1 - 9.9e-41 139.8 0.2 1.4e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAP55336.1 - 1.4e-11 43.5 1.9 2.7e-10 39.3 1.3 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) SBP_bac_7 PF03480.8 OAP55336.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Beta-lactamase PF00144.19 OAP55338.1 - 3.6e-36 124.8 0.0 5.3e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DAP_C PF07932.7 OAP55338.1 - 1.6e-32 111.4 0.0 2.9e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 D-aminopeptidase, domain C DAP_B PF07930.7 OAP55338.1 - 3.6e-08 33.0 0.0 7.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 D-aminopeptidase, domain B La PF05383.12 OAP55340.1 - 2.1e-15 56.2 0.0 3.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 OAP55340.1 - 1.8e-08 34.2 0.0 4.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP55340.1 - 6.8e-08 32.0 0.1 2.1e-07 30.4 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOP5NT PF08156.8 OAP55340.1 - 0.041 14.0 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 NOP5NT (NUC127) domain RRM_5 PF13893.1 OAP55340.1 - 0.057 13.2 0.1 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.18 OAP55341.1 - 5.5e-12 45.3 0.1 2.6e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Exo70 PF03081.10 OAP55342.1 - 3.6e-70 236.6 0.0 4.3e-69 233.0 0.0 2.3 2 1 0 2 2 2 1 Exo70 exocyst complex subunit GAS PF13851.1 OAP55342.1 - 0.011 14.8 0.4 0.55 9.4 0.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PLA2_B PF01735.13 OAP55343.1 - 9.9e-25 86.6 0.0 3.5e-24 84.8 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Phosphodiest PF01663.17 OAP55344.1 - 4e-85 286.3 0.2 5.3e-85 285.9 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF755 PF05501.6 OAP55344.1 - 1.2 9.2 6.3 2.4 8.2 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AATase PF07247.7 OAP55345.1 - 2.1e-22 79.3 0.0 6.8e-22 77.6 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 OAP55345.1 - 2.5e-07 29.8 0.0 3.4e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Condensation domain Abhydrolase_3 PF07859.8 OAP55346.1 - 2.5e-49 167.7 0.0 3.7e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP55346.1 - 8.5e-10 37.9 0.9 2.2e-09 36.5 0.6 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 OAP55346.1 - 2.8e-05 24.1 0.2 5.3e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55346.1 - 0.00057 19.6 0.0 0.00072 19.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF663 PF04950.7 OAP55347.1 - 4e-87 291.9 0.0 3.4e-86 288.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 OAP55347.1 - 2.7e-23 81.2 0.0 5.6e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Ank_2 PF12796.2 OAP55348.1 - 2e-97 319.6 0.0 2.4e-17 63.0 0.0 9.8 4 3 4 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 OAP55348.1 - 2.1e-75 245.0 25.5 9.1e-10 37.8 0.1 19.0 19 0 0 19 19 19 16 Ankyrin repeat Ank_3 PF13606.1 OAP55348.1 - 2.1e-62 200.7 5.6 8.2e-07 28.6 0.0 18.2 18 0 0 18 18 18 10 Ankyrin repeat Ank_4 PF13637.1 OAP55348.1 - 2.9e-62 206.0 1.8 1.2e-07 32.0 0.0 13.3 9 3 6 15 15 15 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP55348.1 - 3.4e-45 151.0 13.0 5.3e-06 26.5 0.0 15.0 12 3 4 16 16 16 10 Ankyrin repeats (many copies) Clr5 PF14420.1 OAP55348.1 - 1.7e-16 59.8 1.1 2.9e-16 59.0 0.8 1.4 1 0 0 1 1 1 1 Clr5 domain 2-Hacid_dh_C PF02826.14 OAP55348.1 - 0.076 12.1 0.0 0.87 8.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shigella_OspC PF06128.6 OAP55348.1 - 0.17 11.3 0.0 6.4 6.1 0.0 3.0 2 0 0 2 2 2 0 Shigella flexneri OspC protein RXT2_N PF08595.6 OAP55349.1 - 0.051 13.3 3.8 10 5.8 0.0 2.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Bromodomain PF00439.20 OAP55350.1 - 2.4e-43 145.9 0.6 1.6e-20 72.7 0.1 2.5 2 0 0 2 2 2 2 Bromodomain Allexi_40kDa PF05549.6 OAP55350.1 - 0.13 11.5 3.3 0.4 9.9 2.3 1.8 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3138 PF11336.3 OAP55350.1 - 0.71 7.9 2.1 3.1 5.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF3573 PF12097.3 OAP55350.1 - 1.4 7.4 4.1 2.2 6.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4407 PF14362.1 OAP55350.1 - 4 6.2 7.9 6.9 5.5 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 OAP55350.1 - 4.4 7.7 9.4 19 5.6 6.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CDC45 PF02724.9 OAP55350.1 - 5.4 4.9 14.5 9.5 4.1 10.0 1.3 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 OAP55350.1 - 7.9 6.0 8.8 18 4.8 6.1 1.5 1 0 0 1 1 1 0 IncA protein Utp12 PF04003.7 OAP55351.1 - 9e-21 73.8 0.2 2.6e-20 72.3 0.1 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family WD40 PF00400.27 OAP55352.1 - 4.7e-12 45.2 0.1 3.6e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF605 PF04652.11 OAP55352.1 - 1.3 8.3 4.0 1.4 8.1 2.8 1.1 1 0 0 1 1 1 0 Vta1 like PPTA PF01239.17 OAP55353.1 - 3e-34 114.9 16.7 5.7e-08 31.7 0.1 6.4 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF469 PF04320.9 OAP55353.1 - 0.55 11.0 3.5 0.69 10.7 0.1 2.8 3 1 0 3 3 3 0 Protein with unknown function (DUF469) RabGAP-TBC PF00566.13 OAP55354.1 - 1e-44 152.6 0.2 2e-43 148.3 0.1 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF972 PF06156.8 OAP55354.1 - 0.33 11.3 21.1 2.7 8.3 4.2 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) PilJ PF13675.1 OAP55354.1 - 0.37 11.1 10.2 3.6 7.9 1.6 3.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DivIC PF04977.10 OAP55354.1 - 0.71 9.3 19.9 0.57 9.7 2.8 3.7 1 1 1 3 3 3 0 Septum formation initiator CCDC155 PF14662.1 OAP55354.1 - 2.9 7.4 29.5 4.2 6.9 10.3 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 TPR_MLP1_2 PF07926.7 OAP55354.1 - 4.3 7.0 36.4 0.9 9.2 20.0 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 OAP55354.1 - 6.4 6.9 14.8 5.5 7.1 3.8 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 OAP55354.1 - 8.3 5.3 29.9 0.88 8.5 8.2 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 AMP-binding PF00501.23 OAP55355.1 - 6.9e-68 228.9 0.0 8.5e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP55355.1 - 4.5e-13 49.9 0.0 8.6e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_30 PF05430.6 OAP55356.1 - 0.0042 16.7 0.0 0.065 12.9 0.0 2.3 2 0 0 2 2 2 1 S-adenosyl-L-methionine-dependent methyltransferase Ctf8 PF09696.5 OAP55357.1 - 5e-36 123.1 0.0 6.1e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Glyco_hydro_32N PF00251.15 OAP55358.1 - 1.8e-26 93.2 0.0 2.7e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 OAP55358.1 - 9.8e-07 29.0 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 OAP55358.1 - 0.15 12.0 1.5 21 5.4 0.0 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat ATP-synt_ab PF00006.20 OAP55359.1 - 8.1e-61 205.2 0.0 1e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAP55359.1 - 9.9e-16 58.2 0.0 1.8e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAP55359.1 - 1.7e-12 47.3 0.3 3.3e-12 46.4 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 OAP55359.1 - 0.0018 18.1 0.2 0.0036 17.1 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain MFS_1 PF07690.11 OAP55360.1 - 9e-16 57.5 17.8 7.5e-15 54.4 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP55360.1 - 2.7e-05 22.9 10.7 9.5e-05 21.1 7.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 OAP55361.1 - 1.3e-27 97.1 2.9 1.3e-27 97.1 2.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP55361.1 - 7.6e-12 45.2 0.0 2e-10 40.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP55361.1 - 8.6e-10 38.5 0.1 3e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 OAP55361.1 - 4.2e-05 22.1 0.0 6e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 OAP55361.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Dicty_CAR PF05462.6 OAP55362.1 - 2.1e-10 40.0 6.9 2.1e-10 40.0 4.8 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 OAP55362.1 - 5e-08 32.7 7.6 7.6e-08 32.1 5.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 OAP55362.1 - 3.4e-06 26.3 2.0 4.7e-06 25.9 1.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 OAP55362.1 - 0.0037 16.4 1.8 0.0076 15.4 0.4 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx PPI_Ypi1 PF07491.6 OAP55363.1 - 8.1e-26 89.4 2.0 2.7e-25 87.7 1.4 1.9 1 1 0 1 1 1 1 Protein phosphatase inhibitor Zip PF02535.17 OAP55363.1 - 1 8.2 3.1 1.1 8.2 2.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 OAP55363.1 - 5 6.4 6.9 7.6 5.8 4.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CRM1_C PF08767.6 OAP55364.1 - 4.5e-135 449.6 3.8 4.5e-135 449.6 2.6 3.0 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 OAP55364.1 - 2e-38 131.6 7.6 2e-38 131.6 5.3 3.4 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 OAP55364.1 - 1.5e-09 37.6 0.0 6.9e-09 35.5 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 OAP55364.1 - 0.024 14.5 0.3 0.19 11.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) uDENN PF03456.13 OAP55364.1 - 0.25 11.3 1.4 0.61 10.0 0.1 2.4 3 0 0 3 3 3 0 uDENN domain bZIP_2 PF07716.10 OAP55365.1 - 2.4e-12 46.4 16.8 5.5e-12 45.3 11.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 OAP55365.1 - 5.8e-07 29.3 12.7 1.6e-06 27.9 8.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor DEC-1_N PF04625.8 OAP55365.1 - 0.0046 15.6 1.0 0.0067 15.1 0.7 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Herpes_BLRF2 PF05812.7 OAP55365.1 - 0.0072 16.1 4.1 0.0072 16.1 2.9 2.0 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein CAF1-p150_N PF15557.1 OAP55365.1 - 0.029 13.6 0.1 0.1 11.9 0.0 1.7 1 1 0 2 2 2 0 CAF1 complex subunit p150, region binding to PCNA TSC22 PF01166.13 OAP55365.1 - 0.051 13.5 2.2 0.11 12.4 1.5 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4284 PF14112.1 OAP55365.1 - 0.33 11.4 2.3 0.5 10.8 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4284) DUF342 PF03961.8 OAP55365.1 - 1 7.7 7.9 1.3 7.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Herpes_UL95 PF03038.9 OAP55365.1 - 1.6 7.5 7.2 2.5 6.8 5.0 1.2 1 0 0 1 1 1 0 UL95 family IncA PF04156.9 OAP55365.1 - 1.9 8.0 9.9 2.7 7.5 6.9 1.2 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 OAP55365.1 - 2.7 7.9 8.6 0.39 10.6 3.0 1.9 2 0 0 2 2 2 0 Haemolysin XhlA YlqD PF11068.3 OAP55365.1 - 6.4 6.8 14.2 4.5 7.3 8.8 1.5 1 1 1 2 2 2 0 YlqD protein V_ATPase_I PF01496.14 OAP55365.1 - 6.5 4.4 9.4 8.3 4.1 6.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL25 PF01499.11 OAP55365.1 - 7.2 4.7 9.7 9.9 4.3 6.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4094 PF13334.1 OAP55365.1 - 8.1 6.9 8.1 0.93 9.9 2.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) HSP70 PF00012.15 OAP55365.1 - 9.6 3.9 13.0 12 3.6 9.0 1.1 1 0 0 1 1 1 0 Hsp70 protein CENP-N PF05238.8 OAP55366.1 - 4.4e-80 269.6 0.0 5.7e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like adh_short_C2 PF13561.1 OAP55367.1 - 5.8e-20 72.0 0.2 6.8e-20 71.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP55367.1 - 9.3e-09 35.4 4.9 1.2e-08 35.0 3.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 OAP55367.1 - 0.00031 20.4 0.7 0.0005 19.7 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 OAP55367.1 - 0.0026 17.4 1.1 0.0037 16.9 0.8 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 OAP55367.1 - 0.003 17.9 1.0 0.029 14.8 0.2 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 OAP55367.1 - 0.0049 17.0 0.3 0.093 12.9 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 OAP55367.1 - 0.037 13.1 0.0 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.14 OAP55367.1 - 0.041 12.5 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 2-Hacid_dh_C PF02826.14 OAP55367.1 - 0.043 12.9 0.1 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAP55367.1 - 0.078 13.0 0.1 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 OAP55368.1 - 6.3e-26 90.8 0.3 9.9e-26 90.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 OAP55368.1 - 1.6e-22 79.4 0.0 3.2e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP55368.1 - 2.3e-15 57.6 0.0 5.4e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP55368.1 - 9.1e-06 25.4 0.1 1.8e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Gal4_dimer PF03902.8 OAP55368.1 - 0.00014 21.7 0.2 0.00042 20.2 0.2 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain CAP_N PF01213.14 OAP55369.1 - 8.5e-87 291.3 0.0 1.3e-86 290.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 OAP55369.1 - 1.7e-56 189.9 3.4 2.3e-56 189.5 2.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 OAP55369.1 - 0.031 13.6 3.6 0.042 13.2 2.0 1.6 1 1 1 2 2 2 0 Tubulin binding cofactor C Metallophos PF00149.23 OAP55370.1 - 2.8e-11 43.1 3.7 2.3e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP55370.1 - 5.6e-10 39.2 0.0 1.4e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PPR_3 PF13812.1 OAP55371.1 - 0.00097 19.2 0.0 0.43 10.9 0.0 3.5 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PET122 PF05476.6 OAP55371.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 PET122 Abhydrolase_6 PF12697.2 OAP55372.1 - 2.4e-24 86.5 0.0 2.8e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55372.1 - 5.2e-08 32.7 0.0 8e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP55372.1 - 3.7e-06 26.6 0.0 0.00097 18.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF900 PF05990.7 OAP55372.1 - 0.0095 15.2 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 OAP55372.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2305 PF10230.4 OAP55372.1 - 0.06 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) IncA PF04156.9 OAP55373.1 - 0.022 14.3 0.1 3.1 7.3 0.3 2.4 2 0 0 2 2 2 0 IncA protein CTP_transf_1 PF01148.15 OAP55375.1 - 1.8e-79 267.0 27.8 2.2e-79 266.7 19.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF1294 PF06961.8 OAP55375.1 - 0.044 13.7 0.2 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) DUF1183 PF06682.7 OAP55375.1 - 0.22 11.1 2.9 0.36 10.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF3636 PF12331.3 OAP55376.1 - 2.8e-41 140.5 1.3 6.3e-41 139.4 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Leu_zip PF15294.1 OAP55376.1 - 0.0024 17.0 5.5 0.0024 17.0 3.8 1.5 2 0 0 2 2 2 1 Leucine zipper CCDC92 PF14916.1 OAP55376.1 - 0.02 14.4 2.9 0.73 9.4 0.4 3.0 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Ground-like PF04155.13 OAP55376.1 - 0.03 14.6 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 Ground-like domain DUF3453 PF11935.3 OAP55376.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Rho_Binding PF08912.6 OAP55376.1 - 0.51 10.6 6.5 0.29 11.4 1.3 2.8 1 1 0 2 2 2 0 Rho Binding Lebercilin PF15619.1 OAP55376.1 - 0.7 9.2 12.2 0.096 12.1 4.0 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 OAP55376.1 - 7.9 6.0 11.3 96 2.4 1.4 2.3 1 1 1 2 2 2 0 IncA protein DUF4129 PF13559.1 OAP55377.1 - 0.088 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) DUF1993 PF09351.5 OAP55378.1 - 8e-55 185.1 0.0 8.9e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Cupin_2 PF07883.6 OAP55379.1 - 1.7e-11 43.4 0.1 3.1e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 OAP55379.1 - 0.0013 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.13 OAP55379.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase PTH2 PF01981.11 OAP55380.1 - 3e-41 139.7 0.2 4.8e-41 139.0 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 VEFS-Box PF09733.4 OAP55380.1 - 0.038 13.6 0.4 0.049 13.2 0.3 1.2 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF688 PF05097.7 OAP55380.1 - 0.22 10.4 2.9 0.3 9.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Nucleoplasmin PF03066.10 OAP55380.1 - 9.2 5.7 10.9 16 4.9 7.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin GFO_IDH_MocA PF01408.17 OAP55381.1 - 1.8e-21 76.8 0.0 8.6e-20 71.4 0.0 2.5 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 OAP55381.1 - 0.14 12.5 0.6 0.46 10.9 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.20 OAP55382.1 - 7.4e-59 199.4 0.0 8.4e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 OAP55382.1 - 0.19 11.1 1.0 0.37 10.2 0.0 2.0 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain APH PF01636.18 OAP55383.1 - 4.9e-05 23.1 0.1 4.9e-05 23.1 0.1 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP55383.1 - 0.0027 17.3 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 OAP55383.1 - 0.05 12.6 0.3 0.05 12.6 0.2 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 OAP55383.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Borrelia_P83 PF05262.6 OAP55383.1 - 0.36 9.0 2.9 0.56 8.4 2.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3359 PF11839.3 OAP55383.1 - 1.2 9.5 12.2 3.4 8.0 8.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) Mnd1 PF03962.10 OAP55383.1 - 7 6.2 6.0 17 5.0 4.2 1.6 1 0 0 1 1 1 0 Mnd1 family PfkB PF00294.19 OAP55384.1 - 4.9e-09 35.7 0.0 1.1e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase ADH_N PF08240.7 OAP55386.1 - 4.4e-11 42.5 0.0 7.9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP55386.1 - 6.2e-11 41.9 0.4 1.1e-10 41.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP55386.1 - 0.0028 18.5 0.3 0.0062 17.4 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 OAP55387.1 - 1.5e-18 66.6 0.9 2.1e-18 66.1 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ribonucleas_3_3 PF14622.1 OAP55389.1 - 1.1e-07 31.7 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 OAP55389.1 - 1.4e-06 28.7 0.0 3.4e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 OAP55389.1 - 0.0061 17.0 0.0 0.018 15.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Gly-zipper_Omp PF13488.1 OAP55390.1 - 0.0031 17.0 2.3 0.0054 16.3 1.6 1.3 1 0 0 1 1 1 1 Glycine zipper PAT1 PF09770.4 OAP55390.1 - 0.016 13.4 11.7 0.02 13.1 8.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gly-zipper_YMGG PF13441.1 OAP55390.1 - 0.19 11.2 5.6 0.29 10.6 3.9 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 OAP55390.1 - 0.2 11.3 10.3 0.31 10.7 7.1 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 OAP55390.1 - 0.87 9.7 5.7 1.3 9.1 3.9 1.1 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Meth_synt_2 PF01717.13 OAP55392.1 - 5.8e-14 51.8 0.0 1.1e-09 37.7 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 OAP55392.1 - 3.1e-05 23.3 0.0 0.04 13.1 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain F-box-like PF12937.2 OAP55393.1 - 0.0032 17.1 0.3 0.017 14.8 0.2 2.4 1 0 0 1 1 1 1 F-box-like AzlD PF05437.7 OAP55393.1 - 0.15 12.0 0.9 0.61 10.0 0.3 2.2 1 1 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DUF3425 PF11905.3 OAP55394.1 - 6.9e-14 51.9 0.1 1.9e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.13 OAP55394.1 - 1.7e-09 37.4 3.9 3e-09 36.6 2.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 OAP55395.1 - 0.00051 20.1 13.9 0.63 10.5 0.5 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP55395.1 - 0.0042 17.3 14.7 0.28 11.5 0.5 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type FlgN PF05130.7 OAP55395.1 - 3.4 7.9 9.6 6.4 7.0 1.0 2.1 1 1 1 2 2 2 0 FlgN protein zf-H2C2_2 PF13465.1 OAP55395.1 - 6.6 7.2 14.5 1.2 9.6 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Choline_transpo PF04515.7 OAP55396.1 - 9.3e-105 350.0 21.6 9.3e-105 350.0 15.0 1.9 2 0 0 2 2 2 1 Plasma-membrane choline transporter SecE PF00584.15 OAP55396.1 - 1.3 8.6 0.0 1.3 8.6 0.0 5.9 8 0 0 8 8 8 0 SecE/Sec61-gamma subunits of protein translocation complex ATPgrasp_Ter PF15632.1 OAP55397.1 - 0.033 12.9 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 OAP55397.1 - 0.065 12.9 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain Ecl1 PF12855.2 OAP55398.1 - 0.00035 19.8 1.1 0.00067 18.8 0.7 1.5 1 0 0 1 1 1 1 Life-span regulatory factor PPR_3 PF13812.1 OAP55399.1 - 7.5e-28 94.4 8.1 5.1e-05 23.2 0.0 11.3 13 0 0 13 13 13 6 Pentatricopeptide repeat domain PPR_2 PF13041.1 OAP55399.1 - 4.5e-25 87.3 0.3 3.7e-07 29.9 0.0 8.5 8 1 2 10 10 10 4 PPR repeat family PPR PF01535.15 OAP55399.1 - 3.5e-19 67.3 0.0 0.0028 17.5 0.0 10.0 10 0 0 10 10 10 3 PPR repeat PPR_1 PF12854.2 OAP55399.1 - 1.6e-12 46.6 0.0 0.0028 17.1 0.0 5.7 7 0 0 7 7 7 3 PPR repeat BRO1 PF03097.13 OAP55400.1 - 0.026 13.2 0.1 0.067 11.9 0.0 1.6 2 0 0 2 2 2 0 BRO1-like domain TPP_enzyme_N PF02776.13 OAP55401.1 - 2e-33 115.3 0.8 4e-33 114.3 0.5 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP55401.1 - 3.5e-18 65.6 0.0 7.7e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 OAP55401.1 - 1.9e-15 56.7 0.0 4.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CoA_binding_2 PF13380.1 OAP55401.1 - 0.03 14.4 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 CoA binding domain MatE PF01554.13 OAP55402.1 - 3.1e-50 169.9 21.4 1e-27 96.7 2.7 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 OAP55402.1 - 5.1e-05 23.1 5.7 5.1e-05 23.1 4.0 4.3 3 2 3 6 6 6 2 Polysaccharide biosynthesis C-terminal domain RabGAP-TBC PF00566.13 OAP55403.1 - 2.1e-32 112.3 0.0 5.2e-32 111.0 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain COPIIcoated_ERV PF07970.7 OAP55404.1 - 2.3e-34 118.9 0.2 4.6e-20 72.1 0.1 2.1 2 0 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 OAP55404.1 - 4.2e-23 81.1 0.0 7.7e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Methyltransf_11 PF08241.7 OAP55406.1 - 4.4e-11 43.1 0.0 8.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP55406.1 - 4.2e-10 39.4 0.0 6.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP55406.1 - 8.2e-10 38.1 0.1 2.2e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 OAP55406.1 - 1.4e-09 38.2 0.0 3.6e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP55406.1 - 5.3e-05 22.9 0.0 7.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP55406.1 - 5.9e-05 23.0 0.0 0.00015 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP55406.1 - 0.00022 21.6 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP55406.1 - 0.00061 19.2 0.0 0.0017 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 OAP55406.1 - 0.0068 16.9 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 OAP55406.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Tropomyosin_1 PF12718.2 OAP55408.1 - 0.0027 17.5 21.1 0.0063 16.3 8.7 2.6 1 1 1 2 2 2 1 Tropomyosin like MCC-bdg_PDZ PF10506.4 OAP55408.1 - 0.11 12.3 5.6 0.14 11.9 0.2 3.1 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Prefoldin PF02996.12 OAP55408.1 - 0.13 11.9 12.1 10 5.8 0.1 4.5 3 1 0 4 4 4 0 Prefoldin subunit IncA PF04156.9 OAP55408.1 - 0.62 9.6 26.7 6.5 6.3 4.2 2.7 1 1 1 2 2 2 0 IncA protein TBPIP PF07106.8 OAP55408.1 - 3.2 7.2 14.0 2 7.9 3.8 2.9 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SPX PF03105.14 OAP55408.1 - 3.5 7.3 7.8 4.8 6.8 4.7 1.8 1 1 0 1 1 1 0 SPX domain Myosin_tail_1 PF01576.14 OAP55408.1 - 3.7 5.1 26.1 3.1 5.4 12.1 2.3 2 1 0 2 2 2 0 Myosin tail APG6 PF04111.7 OAP55408.1 - 5.4 5.9 21.7 9.5 5.1 10.4 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 GAS PF13851.1 OAP55408.1 - 5.8 6.0 20.2 1.1 8.4 6.6 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 OAP55408.1 - 7.1 6.3 24.7 1.1 9.0 7.7 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 OAP55408.1 - 7.4 6.4 24.8 5.5 6.8 6.8 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MbeD_MobD PF04899.7 OAP55408.1 - 9.3 6.2 12.8 5.4 6.9 4.4 3.0 3 0 0 3 3 3 0 MbeD/MobD like WD40 PF00400.27 OAP55409.1 - 1.3e-21 75.6 17.2 1.4e-08 34.2 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat SUKH_6 PF14568.1 OAP55409.1 - 0.038 14.4 0.1 0.088 13.2 0.1 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall PS_Dcarbxylase PF02666.10 OAP55410.1 - 1.1e-46 158.6 0.0 1.5e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase SET PF00856.23 OAP55411.1 - 0.0018 18.5 0.6 0.056 13.7 0.4 2.7 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 OAP55411.1 - 0.0033 17.2 6.4 0.0033 17.2 4.5 2.3 2 0 0 2 2 2 1 MYND finger PAP2 PF01569.16 OAP55412.1 - 8.1e-16 57.8 4.0 8.1e-16 57.8 2.8 2.0 2 0 0 2 2 2 1 PAP2 superfamily DUF3976 PF13121.1 OAP55412.1 - 0.048 13.5 1.2 4.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) Spo7 PF03907.8 OAP55413.1 - 1e-62 211.4 0.1 1.5e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein DUF4391 PF14335.1 OAP55413.1 - 4 6.7 8.0 7.5 5.8 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) CAF-1_p150 PF11600.3 OAP55413.1 - 8.4 5.7 30.7 0.062 12.6 14.2 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Abhydrolase_6 PF12697.2 OAP55414.1 - 2.6e-28 99.4 0.4 8.8e-28 97.7 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP55414.1 - 1.1e-16 61.1 0.0 4.7e-15 55.7 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP55414.1 - 5.7e-14 52.0 0.0 3.2e-11 43.1 0.0 2.6 2 1 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 OAP55414.1 - 6.4e-07 29.0 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 OAP55414.1 - 0.00016 20.8 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 OAP55414.1 - 0.00096 18.6 0.0 0.0024 17.3 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 OAP55414.1 - 0.001 18.0 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 OAP55414.1 - 0.0012 18.6 0.0 0.0049 16.6 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 OAP55414.1 - 0.0081 15.6 0.0 2.7 7.3 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 OAP55414.1 - 0.011 15.3 0.2 0.07 12.6 0.0 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold Chlorophyllase PF07224.6 OAP55414.1 - 0.036 12.8 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.20 OAP55414.1 - 0.05 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 OAP55414.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 OAP55414.1 - 0.08 12.1 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.15 OAP55414.1 - 0.22 11.7 2.6 0.65 10.1 0.4 2.5 2 1 0 2 2 2 0 Thioesterase domain ADH_zinc_N PF00107.21 OAP55415.1 - 2.3e-12 46.5 0.0 7.7e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP55415.1 - 1.1e-06 28.3 0.2 1.3e-05 24.8 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP55415.1 - 0.0026 18.6 0.1 0.0081 17.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NmrA PF05368.8 OAP55416.1 - 1.1e-09 37.8 0.0 3.7e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP55416.1 - 2.8e-05 24.1 2.2 0.00012 22.1 0.5 2.6 2 1 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 OAP55416.1 - 0.0026 16.7 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Homeobox PF00046.24 OAP55417.1 - 2.3e-14 52.7 0.7 6e-14 51.4 0.5 1.8 1 0 0 1 1 1 1 Homeobox domain RepB-RCR_reg PF10723.4 OAP55417.1 - 0.012 15.2 1.2 5.1 6.9 0.1 3.1 3 0 0 3 3 3 0 Replication regulatory protein RepB Amino_oxidase PF01593.19 OAP55418.1 - 3.1e-41 141.9 2.9 2e-22 79.9 0.3 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP55418.1 - 2.7e-15 56.1 0.5 6.6e-15 54.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP55418.1 - 2.1e-08 33.5 0.1 2e-05 23.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP55418.1 - 8.1e-07 29.3 0.9 1.2e-05 25.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP55418.1 - 2.1e-05 24.4 0.4 0.00015 21.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP55418.1 - 4e-05 22.8 0.1 6.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAP55418.1 - 8.6e-05 21.5 0.6 0.00052 18.9 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 OAP55418.1 - 0.00014 21.6 0.8 0.35 10.6 0.1 3.0 2 1 1 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 OAP55418.1 - 0.00022 19.8 0.4 0.00049 18.6 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 OAP55418.1 - 0.00038 19.4 0.4 0.00071 18.5 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAP55418.1 - 0.00039 20.5 0.5 0.0011 19.0 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP55418.1 - 0.0007 18.7 0.3 0.0012 17.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAP55418.1 - 0.001 18.2 0.4 0.0017 17.5 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 OAP55418.1 - 0.0031 17.1 0.5 0.0067 16.0 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 OAP55418.1 - 0.14 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF4407 PF14362.1 OAP55419.1 - 0.32 9.8 3.3 0.41 9.5 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lactamase_B_2 PF12706.2 OAP55420.1 - 1.1e-30 106.6 0.0 1.7e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP55420.1 - 9e-07 28.7 0.0 2.7e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAP55420.1 - 0.072 12.7 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Protoglobin PF11563.3 OAP55421.1 - 3.3e-51 173.0 0.3 4.1e-51 172.7 0.2 1.1 1 0 0 1 1 1 1 Protoglobin Hexapep PF00132.19 OAP55422.1 - 3.9e-11 41.9 7.2 1.4e-05 24.3 0.6 4.9 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAP55422.1 - 1.6e-05 24.3 0.3 0.00044 19.7 0.1 3.2 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Cyclin_N PF00134.18 OAP55426.1 - 2.5e-11 43.2 0.0 4.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 OAP55426.1 - 1.3e-10 41.9 0.0 2.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin PIG-F PF06699.6 OAP55427.1 - 2.5e-31 109.0 13.8 2.5e-30 105.8 9.6 2.0 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F AAA_11 PF13086.1 OAP55429.1 - 4.2e-59 199.9 0.0 8.2e-59 199.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 OAP55429.1 - 9e-57 191.6 0.0 3.3e-56 189.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAP55429.1 - 3.2e-13 49.2 0.1 5e-12 45.4 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 OAP55429.1 - 1.3e-11 44.4 0.0 4.3e-09 36.2 0.0 2.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 OAP55429.1 - 6.6e-09 35.1 0.0 7.1e-08 31.7 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 OAP55429.1 - 3.2e-07 30.3 0.0 9.2e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 OAP55429.1 - 1.5e-06 27.8 0.0 0.13 11.7 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 OAP55429.1 - 1.3e-05 24.6 0.0 3.6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 OAP55429.1 - 5.1e-05 22.3 0.0 0.17 10.8 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_22 PF13401.1 OAP55429.1 - 6.9e-05 23.0 0.1 0.0027 17.8 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 OAP55429.1 - 0.00024 21.1 0.0 0.00055 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 OAP55429.1 - 0.00035 20.2 0.0 0.037 13.6 0.0 3.1 2 1 0 2 2 2 1 Helicase UvrD_C PF13361.1 OAP55429.1 - 0.00067 19.2 0.2 1.3 8.4 0.0 3.0 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain DEAD PF00270.24 OAP55429.1 - 0.001 18.6 0.1 0.01 15.3 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 OAP55429.1 - 0.0018 17.5 0.0 0.018 14.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_5 PF07728.9 OAP55429.1 - 0.0019 17.9 0.1 0.019 14.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 OAP55429.1 - 0.0051 15.7 0.1 0.015 14.2 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 OAP55429.1 - 0.0081 15.6 0.0 0.037 13.4 0.0 1.9 1 1 0 2 2 2 1 AAA-like domain Zot PF05707.7 OAP55429.1 - 0.0086 15.5 0.0 0.049 13.0 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.13 OAP55429.1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 OAP55429.1 - 0.013 14.1 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 OAP55429.1 - 0.015 15.4 0.0 0.059 13.5 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 OAP55429.1 - 0.022 14.1 0.0 0.098 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 OAP55429.1 - 0.032 14.3 0.1 0.69 10.0 0.0 2.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain 4HB_MCP_1 PF12729.2 OAP55429.1 - 0.057 12.7 1.3 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction AAA_14 PF13173.1 OAP55429.1 - 0.061 13.2 0.0 0.26 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 OAP55429.1 - 0.062 13.5 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter IstB_IS21 PF01695.12 OAP55429.1 - 0.099 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 OAP55429.1 - 0.1 12.9 0.0 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.9 OAP55429.1 - 0.13 12.0 0.0 0.59 9.8 0.0 2.2 3 0 0 3 3 2 0 Flavivirus DEAD domain Methyltransf_23 PF13489.1 OAP55430.1 - 1e-14 54.5 0.0 2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP55430.1 - 5.8e-06 26.7 0.0 1.4e-05 25.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP55430.1 - 1.7e-05 25.3 0.0 0.00012 22.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP55430.1 - 0.00026 20.5 0.0 0.00088 18.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP55430.1 - 0.0053 17.2 0.0 0.019 15.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAP55430.1 - 0.0065 16.4 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 OAP55430.1 - 0.007 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 OAP55430.1 - 0.0097 16.2 0.0 0.034 14.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAP55430.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 OAP55430.1 - 0.018 14.2 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 OAP55430.1 - 0.047 12.8 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 OAP55430.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Serpulina_VSP PF05540.6 OAP55430.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein p450 PF00067.17 OAP55431.1 - 7.7e-50 169.7 0.0 2.5e-49 168.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 RINGv PF12906.2 OAP55432.1 - 7.1e-06 25.9 4.1 1.1e-05 25.3 1.2 2.1 2 0 0 2 2 2 1 RING-variant domain Rep_fac_C PF08542.6 OAP55434.1 - 2.7e-23 81.7 0.0 5.7e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 OAP55434.1 - 2.5e-10 40.2 0.0 4.3e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 OAP55434.1 - 3.2e-06 27.3 0.2 9.8e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP55434.1 - 7.5e-05 22.8 0.3 0.00045 20.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAP55434.1 - 0.00092 19.2 0.1 0.027 14.5 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 OAP55434.1 - 0.0038 17.2 2.1 0.12 12.3 0.6 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 OAP55434.1 - 0.013 15.4 0.1 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 OAP55434.1 - 0.018 14.5 0.1 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 OAP55434.1 - 0.034 13.7 0.4 0.11 12.1 0.3 1.7 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 OAP55434.1 - 0.056 12.2 0.1 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 OAP55434.1 - 0.11 11.9 0.1 1 8.7 0.0 2.0 1 1 0 2 2 2 0 AAA-like domain Ribonuclease_3 PF00636.21 OAP55435.1 - 1e-35 122.6 0.0 7.3e-18 65.0 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAP55435.1 - 5.1e-24 84.6 0.0 8.2e-12 45.2 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 OAP55435.1 - 7.9e-18 64.0 0.0 2.1e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 OAP55435.1 - 1.6e-15 56.9 0.0 1.1e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP55435.1 - 1.6e-12 47.1 0.0 5.4e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP55435.1 - 5.8e-09 36.0 0.2 1.3e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit dsrm PF00035.20 OAP55435.1 - 3 8.4 4.2 4.1 8.0 0.4 2.8 2 0 0 2 2 2 0 Double-stranded RNA binding motif EF-hand_6 PF13405.1 OAP55436.1 - 0.0022 17.7 0.0 0.0072 16.1 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 OAP55436.1 - 0.013 15.6 0.1 0.06 13.5 0.0 1.9 1 1 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 OAP55436.1 - 0.041 13.2 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 OAP55436.1 - 0.12 11.7 0.0 0.43 10.0 0.0 1.9 1 0 0 1 1 1 0 EF hand Isochorismatase PF00857.15 OAP55437.1 - 1.6e-20 73.7 0.0 3.6e-20 72.6 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family Methyltransf_11 PF08241.7 OAP55438.1 - 9e-06 26.0 0.0 2.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain His_Phos_1 PF00300.17 OAP55439.1 - 2.2e-29 102.6 0.1 2.8e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ArfGap PF01412.13 OAP55441.1 - 1.1e-34 118.7 2.1 1.1e-34 118.6 0.4 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Pol_alpha_B_N PF08418.5 OAP55441.1 - 0.096 12.2 17.4 0.27 10.7 3.1 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal CHCH PF06747.8 OAP55443.1 - 3.1e-06 26.9 5.7 4.8e-06 26.3 4.0 1.3 1 0 0 1 1 1 1 CHCH domain HATPase_c PF02518.21 OAP55444.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_85 PF03644.8 OAP55445.1 - 1.2e-52 178.9 1.2 4.1e-50 170.6 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 85 TPK_catalytic PF04263.11 OAP55446.1 - 4.6e-22 77.8 0.0 6.7e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 OAP55446.1 - 7.3e-18 64.0 0.0 1.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain MIF4G PF02854.14 OAP55447.1 - 1.2e-61 207.7 0.1 2.4e-31 108.8 0.1 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 OAP55447.1 - 1.9e-27 96.1 29.1 5.2e-14 52.3 11.6 3.4 2 1 1 3 3 3 2 Up-frameshift suppressor 2 AbbA_antirepres PF14156.1 OAP55447.1 - 0.025 14.2 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Antirepressor AbbA Ribosomal_L1 PF00687.16 OAP55448.1 - 6.1e-55 185.9 1.1 8.4e-55 185.4 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Vfa1 PF08432.5 OAP55448.1 - 0.081 12.9 0.3 0.081 12.9 0.2 2.8 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 ETF PF01012.16 OAP55450.1 - 4e-41 140.4 0.3 1.1e-40 139.0 0.1 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 OAP55450.1 - 1e-35 121.1 0.1 1.8e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Fungal_trans PF04082.13 OAP55451.1 - 1.5e-11 43.6 0.2 3e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55451.1 - 5.1e-07 29.4 7.5 5.1e-07 29.4 5.2 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HLH PF00010.21 OAP55452.1 - 9.8e-09 34.7 0.2 5.5e-08 32.3 0.1 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1917 PF08939.5 OAP55452.1 - 0.0021 17.8 0.6 0.0038 17.0 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Cut8_N PF14482.1 OAP55452.1 - 0.053 13.5 3.1 0.86 9.6 0.3 3.1 2 0 0 2 2 2 0 Cut8 proteasome-binding domain REV PF00424.13 OAP55452.1 - 1.9 8.4 8.6 1.1 9.2 2.8 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) PBP1_TM PF14812.1 OAP55452.1 - 3.7 7.9 12.7 1.4 9.3 3.8 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HLH PF00010.21 OAP55453.1 - 3.1e-08 33.2 0.2 1.2e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Gly_rich PF12810.2 OAP55453.1 - 0.041 13.4 3.0 0.02 14.4 0.7 1.5 2 0 0 2 2 2 0 Glycine rich protein OrfB_IS605 PF01385.14 OAP55453.1 - 1.7 8.0 6.8 2.9 7.2 4.7 1.3 1 0 0 1 1 1 0 Probable transposase FlaG PF03646.10 OAP55453.1 - 6.4 6.9 7.2 39 4.4 2.5 2.2 2 0 0 2 2 2 0 FlaG protein Fungal_trans PF04082.13 OAP55454.1 - 4.9e-12 45.2 4.5 7.8e-12 44.6 3.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55454.1 - 3.6e-06 26.7 10.0 8.2e-06 25.6 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP55455.1 - 6.5e-29 100.7 57.1 1.4e-18 66.7 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP55455.1 - 1.7 8.5 11.9 2.5 7.9 0.9 3.6 2 1 1 3 3 3 0 MFS_1 like family HTH_25 PF13413.1 OAP55456.1 - 0.089 12.4 0.2 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2110 PF09883.4 OAP55456.1 - 0.15 11.7 1.6 3.6 7.1 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) DUF4600 PF15372.1 OAP55456.1 - 3.1 8.0 13.2 0.19 11.9 4.7 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4600) AATF-Che1 PF13339.1 OAP55456.1 - 3.5 7.7 11.0 0.42 10.7 4.2 1.9 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor PPP4R2 PF09184.6 OAP55457.1 - 0.11 11.9 5.7 0.17 11.3 3.9 1.3 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.13 OAP55457.1 - 0.13 11.3 5.8 0.083 12.0 2.6 1.7 2 0 0 2 2 2 0 Myc amino-terminal region PBP1_TM PF14812.1 OAP55457.1 - 0.36 11.1 3.9 0.77 10.1 2.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VID27 PF08553.5 OAP55457.1 - 0.44 8.7 5.3 0.55 8.3 3.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ribosomal_60s PF00428.14 OAP55457.1 - 0.63 10.4 13.6 1.3 9.4 9.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOA36 PF06524.7 OAP55457.1 - 1.7 7.8 7.9 2.5 7.2 5.4 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 OAP55457.1 - 1.8 8.0 9.8 3.1 7.2 6.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAP55457.1 - 4.3 6.9 9.2 7.1 6.1 6.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 OAP55457.1 - 6.6 7.0 10.1 14 6.0 7.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 OAP55457.1 - 8.6 4.1 9.9 12 3.6 6.8 1.2 1 0 0 1 1 1 0 Nop14-like family adh_short PF00106.20 OAP55458.1 - 2.8e-21 76.1 0.4 4.2e-21 75.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP55458.1 - 8.5e-10 38.5 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP55458.1 - 3e-09 36.9 0.0 3.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP55458.1 - 0.0064 15.9 0.2 0.012 15.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAP55458.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 OAP55458.1 - 0.046 13.5 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_72 PF03198.9 OAP55460.1 - 1.7e-135 451.0 1.1 2e-135 450.7 0.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 OAP55460.1 - 4.4e-07 29.3 0.1 1.1e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 OAP55460.1 - 0.0022 16.9 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DNA_binding_1 PF01035.15 OAP55461.1 - 2e-26 91.5 0.0 2.7e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain NDUF_B7 PF05676.8 OAP55462.1 - 1.4e-30 104.5 2.7 1.7e-30 104.2 1.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 OAP55462.1 - 0.00087 19.0 2.7 0.0012 18.6 1.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.11 OAP55463.1 - 6.9e-151 502.5 0.0 1e-119 399.9 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase CorA PF01544.13 OAP55464.1 - 2.1e-05 23.7 0.0 2.1e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Transp_cyt_pur PF02133.10 OAP55465.1 - 2.7e-148 494.2 43.8 3.1e-148 493.9 30.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_4 PF01565.18 OAP55466.1 - 5.8e-23 80.8 0.2 1.8e-22 79.3 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAP55466.1 - 8.7e-14 51.1 0.7 2.3e-13 49.8 0.4 1.8 2 0 0 2 2 2 1 Berberine and berberine like Fungal_lectin PF07938.7 OAP55467.1 - 1.2e-06 28.1 0.0 1.4e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Fungal fucose-specific lectin DUF3328 PF11807.3 OAP55469.1 - 0.00057 19.6 0.6 0.0068 16.1 0.2 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) DUF3328 PF11807.3 OAP55470.1 - 3.1e-10 40.1 0.4 5.8e-10 39.2 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2763 PF10961.3 OAP55470.1 - 0.093 13.1 1.2 0.43 10.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) PepSY_TM PF03929.11 OAP55470.1 - 0.2 12.1 3.4 0.47 10.9 2.3 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix DUF3328 PF11807.3 OAP55471.1 - 1.5e-48 165.3 3.5 5.2e-48 163.5 2.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Antifungal_pept PF11410.3 OAP55472.1 - 0.16 12.0 31.9 3.7 7.7 0.4 6.2 6 0 0 6 6 6 0 Antifungal peptide BID PF06393.6 OAP55472.1 - 5.3 6.3 8.2 15 4.8 0.1 3.5 3 1 0 4 4 4 0 BH3 interacting domain (BID) CBM_19 PF03427.8 OAP55472.1 - 7.5 6.4 12.8 29 4.5 0.0 5.1 6 0 0 6 6 6 0 Carbohydrate binding domain (family 19) DUF1771 PF08590.5 OAP55473.1 - 1.3e-23 82.7 10.7 1.3e-23 82.7 7.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 OAP55473.1 - 3.5e-17 62.3 0.2 8e-17 61.2 0.2 1.7 1 0 0 1 1 1 1 Smr domain Fungal_trans PF04082.13 OAP55474.1 - 1.3e-12 47.1 0.1 2.9e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2791 PF10923.3 OAP55474.1 - 0.073 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) G-alpha PF00503.15 OAP55475.1 - 6.9e-134 446.3 0.6 8.4e-134 446.1 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAP55475.1 - 8.9e-16 57.6 1.1 1.2e-10 40.9 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 OAP55475.1 - 0.00039 19.9 0.0 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 OAP55475.1 - 0.0022 18.4 1.2 2.8 8.4 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 OAP55475.1 - 0.0089 15.1 4.8 0.11 11.6 0.2 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 OAP55475.1 - 0.014 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 OAP55475.1 - 0.033 13.6 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 OAP55475.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.18 OAP55475.1 - 0.076 11.7 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 OAP55475.1 - 0.086 12.7 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Abhydrolase_1 PF00561.15 OAP55476.1 - 2.5e-21 76.2 0.2 1.8e-20 73.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 OAP55476.1 - 1.5e-12 47.3 0.1 3.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 OAP55476.1 - 6.3e-10 39.3 0.1 1.4e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55476.1 - 0.029 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.11 OAP55477.1 - 3.9e-30 104.7 26.6 3.9e-30 104.7 18.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 OAP55478.1 - 2.6e-14 53.7 0.0 6.3e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP55478.1 - 2.8e-13 49.9 0.0 4.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4073 PF13285.1 OAP55478.1 - 0.04 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) IDO PF01231.13 OAP55479.1 - 3.9e-168 559.2 0.0 4.5e-168 559.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 OAP55482.1 - 6.1e-39 132.4 0.0 1.2e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 OAP55482.1 - 2.6e-14 52.5 0.0 4.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 OAP55482.1 - 0.0035 16.7 0.1 0.012 15.0 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Reo_sigmaC PF04582.7 OAP55482.1 - 0.72 8.9 4.6 1 8.4 3.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CsbD PF05532.7 OAP55483.1 - 1.4e-11 43.8 19.0 4.7e-10 38.9 4.6 3.3 2 1 1 3 3 3 3 CsbD-like UPF0444 PF15475.1 OAP55483.1 - 0.047 13.7 2.2 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 LLC1 PF14945.1 OAP55483.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein HET PF06985.6 OAP55485.1 - 7.9e-32 110.3 0.5 1.6e-31 109.3 0.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.19 OAP55486.1 - 6e-23 81.0 29.5 6.5e-13 48.4 5.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1774 PF08611.5 OAP55486.1 - 0.021 14.9 3.0 4.8 7.3 0.0 3.3 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1774) DUF165 PF02592.10 OAP55486.1 - 1.9 8.6 10.5 5.3 7.2 3.5 3.1 2 1 1 3 3 3 0 Uncharacterized ACR, YhhQ family COG1738 Use1 PF09753.4 OAP55487.1 - 1.2e-07 31.4 0.1 1.7e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 DrrA_P4M PF14860.1 OAP55487.1 - 0.18 11.5 0.2 0.18 11.5 0.1 1.8 3 0 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain PhyH PF05721.8 OAP55488.1 - 4.4e-21 75.8 0.2 7.3e-21 75.1 0.1 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Transp_cyt_pur PF02133.10 OAP55489.1 - 3.9e-82 276.1 43.7 4.9e-82 275.8 30.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidohydro_4 PF13147.1 OAP55490.1 - 2e-25 90.3 0.1 5.2e-25 89.0 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 OAP55490.1 - 3.7e-14 52.2 1.2 1.4e-13 50.4 0.8 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 OAP55490.1 - 1.4e-13 51.1 1.9 7.8e-11 42.1 1.3 2.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 OAP55490.1 - 4.3e-09 36.0 0.2 7.9e-05 22.0 0.0 3.2 3 0 0 3 3 3 3 Amidohydrolase family Cu-oxidase_4 PF02578.10 OAP55490.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase Urease_alpha PF00449.15 OAP55490.1 - 0.049 13.7 0.4 0.15 12.2 0.3 1.9 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain FAA_hydrolase PF01557.13 OAP55491.1 - 1.4e-41 142.3 0.1 1.4e-40 139.1 0.0 2.2 1 1 1 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 OAP55491.1 - 3.1e-23 81.7 0.0 8.3e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.13 OAP55491.1 - 5.4e-21 74.6 0.8 8.7e-21 73.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55493.1 - 1.5e-07 31.2 13.2 2.5e-07 30.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP55493.1 - 5.5e-06 25.4 0.1 1.1e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 OAP55494.1 - 2.8e-31 107.4 0.2 5.1e-31 106.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP55494.1 - 4.7e-16 58.5 0.1 9.4e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP55494.1 - 1.3e-05 26.0 0.0 2.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAP55494.1 - 0.058 12.7 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aminotran_5 PF00266.14 OAP55495.1 - 1.9e-92 309.9 0.0 2.3e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 OAP55495.1 - 5.6e-07 28.9 0.0 8.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 OAP55495.1 - 4e-05 22.8 0.0 0.0001 21.4 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 OAP55495.1 - 0.004 15.4 0.0 0.0061 14.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 OAP55495.1 - 0.042 12.2 0.0 0.062 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.13 OAP55496.1 - 5.2e-62 209.3 7.2 6.5e-62 209.0 5.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 OAP55496.1 - 1.3e-14 53.2 0.1 3e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAP55496.1 - 2.1e-12 46.4 0.1 4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAP55496.1 - 3.8e-11 42.2 0.4 1.1e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.5 OAP55496.1 - 0.15 11.2 7.9 3.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Vps5 C terminal like TMPIT PF07851.8 OAP55496.1 - 7.6 5.5 9.1 0.22 10.5 0.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein Urb2 PF10441.4 OAP55498.1 - 6.8e-52 176.2 0.0 2.5e-51 174.4 0.0 2.0 1 0 0 1 1 1 1 Urb2/Npa2 family DUF543 PF04418.7 OAP55499.1 - 5.5e-27 93.5 0.0 6.6e-27 93.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) End3 PF12761.2 OAP55500.1 - 4.2e-65 219.0 0.8 6.1e-65 218.5 0.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 OAP55500.1 - 5.8e-49 164.1 0.0 4.6e-46 154.8 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 OAP55500.1 - 6.9e-09 34.3 0.2 4e-07 28.8 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 OAP55500.1 - 8.1e-08 31.7 0.3 2.5e-05 23.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 OAP55500.1 - 9.2e-08 32.1 0.1 0.00012 22.1 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 OAP55500.1 - 2.3e-07 30.1 0.4 0.00025 20.6 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 OAP55500.1 - 0.00094 18.4 0.2 0.0026 17.0 0.2 1.8 1 0 0 1 1 1 1 EF hand TPR_MLP1_2 PF07926.7 OAP55500.1 - 0.0097 15.6 8.9 0.036 13.7 0.1 2.6 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 OAP55500.1 - 3.2 7.6 14.3 0.081 12.7 2.8 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.14 OAP55500.1 - 4.7 6.7 7.7 0.36 10.3 1.7 1.9 2 0 0 2 2 2 0 GrpE Amnionless PF14828.1 OAP55501.1 - 0.00017 20.2 0.0 0.00019 20.0 0.0 1.1 1 0 0 1 1 1 1 Amnionless Shisa PF13908.1 OAP55501.1 - 0.0018 18.4 0.0 0.0021 18.2 0.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Gastrin PF00918.12 OAP55501.1 - 0.073 13.8 0.1 0.093 13.5 0.1 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family MscS_TM PF12794.2 OAP55501.1 - 0.12 10.9 0.4 0.14 10.7 0.3 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Conotoxin PF02950.12 OAP55501.1 - 0.28 12.0 1.6 0.64 10.8 1.1 1.7 1 1 0 1 1 1 0 Conotoxin HhH-GPD PF00730.20 OAP55502.1 - 2.3e-14 53.5 0.0 4.6e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAP55502.1 - 4.7e-07 29.1 0.0 1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif UQ_con PF00179.21 OAP55503.1 - 9.6e-37 125.5 0.0 1.1e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP55503.1 - 0.062 13.0 0.0 0.096 12.4 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 OAP55503.1 - 0.079 12.8 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Proteasome PF00227.21 OAP55504.1 - 3.8e-57 192.6 0.0 7e-33 113.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 OAP55504.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3736 PF12540.3 OAP55505.1 - 1.6 8.9 6.8 1.7 8.8 4.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3736) TPR_1 PF00515.23 OAP55506.1 - 2.1e-54 179.0 34.2 2.3e-08 33.2 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 OAP55506.1 - 1.1e-47 156.1 26.4 1.2e-06 27.9 0.0 10.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 OAP55506.1 - 2.2e-45 152.1 26.5 4.9e-11 42.1 0.8 6.6 3 2 3 6 6 6 6 TPR repeat TPR_8 PF13181.1 OAP55506.1 - 1.4e-40 133.9 23.8 3.4e-06 26.4 0.0 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 OAP55506.1 - 5.9e-34 116.0 15.3 5.3e-07 30.1 0.1 6.6 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAP55506.1 - 1.6e-30 104.8 26.8 3.8e-07 29.9 0.4 7.5 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 OAP55506.1 - 1.2e-26 90.6 22.0 0.00063 19.7 0.1 11.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAP55506.1 - 1.6e-25 87.2 15.3 1.4e-05 25.3 0.1 9.5 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 OAP55506.1 - 3e-23 81.9 18.6 4.8e-07 30.0 0.1 6.8 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 OAP55506.1 - 7.8e-22 75.2 16.3 0.005 16.5 0.0 9.8 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 OAP55506.1 - 4.8e-21 73.7 21.5 0.00017 21.7 0.0 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.1 OAP55506.1 - 1.3e-15 56.9 14.0 0.0013 18.5 0.1 6.8 1 1 8 9 9 9 7 Tetratricopeptide repeat Apc3 PF12895.2 OAP55506.1 - 2.9e-12 46.5 16.9 4.9e-07 29.7 1.3 4.0 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 OAP55506.1 - 3.9e-09 35.9 15.9 0.0029 16.7 1.6 4.6 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.4 OAP55506.1 - 6.7e-07 29.3 10.9 0.011 15.6 2.2 4.3 3 2 2 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAP55506.1 - 9.7e-05 22.1 0.8 0.14 12.0 0.0 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 OAP55506.1 - 0.0092 14.7 6.3 0.92 8.2 0.3 3.4 3 1 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.12 OAP55506.1 - 0.019 15.2 10.0 0.24 11.7 0.2 3.8 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 OAP55506.1 - 0.029 14.4 8.6 0.45 10.6 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat FAT PF02259.18 OAP55506.1 - 0.3 10.0 8.2 1.6 7.6 3.2 2.9 2 1 0 2 2 2 0 FAT domain Ribosomal_L3 PF00297.17 OAP55507.1 - 2.9e-118 394.0 8.8 3.3e-118 393.8 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.6 OAP55508.1 - 0.0075 16.1 1.3 2.8 7.8 0.7 2.2 2 0 0 2 2 2 2 Nuclease A inhibitor-like protein SKN1 PF03935.10 OAP55509.1 - 6.3e-231 766.8 0.8 7.4e-231 766.6 0.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF2360 PF10152.4 OAP55510.1 - 0.05 13.8 0.8 0.066 13.4 0.5 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Cnd2 PF05786.9 OAP55510.1 - 0.056 11.9 0.1 0.058 11.8 0.1 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 NUC173 PF08161.7 OAP55511.1 - 4.3e-71 238.3 0.0 8.5e-70 234.1 0.0 2.9 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.17 OAP55511.1 - 1.6e-05 24.5 1.8 1.7 8.9 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat Nipped-B_C PF12830.2 OAP55511.1 - 0.037 13.6 0.7 0.18 11.4 0.0 2.6 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus RasGAP PF00616.14 OAP55511.1 - 0.062 12.9 0.1 0.062 12.9 0.0 2.5 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase NmrA PF05368.8 OAP55512.1 - 2e-06 27.2 0.0 4e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP55512.1 - 3.1e-06 27.3 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 OAP55512.1 - 0.004 17.1 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 OAP55512.1 - 0.027 14.8 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 OAP55512.1 - 0.027 13.8 0.2 0.26 10.6 0.0 2.4 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP55512.1 - 0.062 11.9 0.1 0.2 10.2 0.0 1.8 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family HET PF06985.6 OAP55513.1 - 1.4e-22 80.3 0.2 2.9e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2415 PF10313.4 OAP55515.1 - 1.6e-13 50.0 0.0 3.8e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 OAP55515.1 - 1.9e-05 24.3 3.0 1.8 8.5 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat CENP-K PF11802.3 OAP55515.1 - 2.3 7.3 5.6 1.3 8.1 2.2 1.7 2 0 0 2 2 2 0 Centromere-associated protein K HSP70 PF00012.15 OAP55516.1 - 9.5e-270 895.7 16.9 1.1e-269 895.5 11.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAP55516.1 - 5e-14 51.6 10.8 6.4e-13 47.9 2.7 3.1 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 OAP55516.1 - 6.1e-05 22.7 0.2 0.00024 20.8 0.1 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 OAP55516.1 - 0.0032 17.2 9.4 1.2 8.9 0.8 4.8 3 3 0 3 3 3 2 Cell division protein FtsA DUF4363 PF14276.1 OAP55516.1 - 0.013 15.1 4.6 0.029 14.0 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Rab5ip PF07019.7 OAP55518.1 - 3.1e-12 46.4 7.2 4.3e-11 42.7 5.0 2.0 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SAM_2 PF07647.12 OAP55519.1 - 1.6e-09 37.4 0.1 1.1e-07 31.5 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAP55519.1 - 7.9e-06 25.9 0.1 2e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) His_Phos_1 PF00300.17 OAP55520.1 - 0.00016 21.7 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Integrin_alpha PF00357.15 OAP55520.1 - 0.23 11.3 1.0 0.5 10.2 0.7 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region adh_short PF00106.20 OAP55522.1 - 2.2e-16 60.2 0.0 2.2e-16 60.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP55522.1 - 8.4e-11 41.8 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 OAP55522.1 - 0.0039 16.1 0.2 0.046 12.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 OAP55522.1 - 0.0061 15.4 0.0 0.0099 14.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 OAP55522.1 - 0.055 12.8 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LSM PF01423.17 OAP55523.1 - 9.5e-12 44.3 0.0 1.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain Lipase_GDSL_2 PF13472.1 OAP55524.1 - 0.0061 16.7 0.0 0.0098 16.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BCDHK_Adom3 PF10436.4 OAP55525.1 - 1.6e-70 235.8 0.0 2.4e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAP55525.1 - 2.6e-17 62.5 0.0 9.1e-17 60.7 0.0 2.0 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAP55525.1 - 0.0091 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IBP39 PF11422.3 OAP55526.1 - 0.07 12.6 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Initiator binding protein 39 kDa RPOL_N PF14700.1 OAP55526.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal SnoaL PF07366.7 OAP55527.1 - 3.5e-22 78.3 0.0 4.3e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 OAP55527.1 - 2e-12 47.4 0.0 2.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF1754 PF08555.5 OAP55528.1 - 2.8e-13 50.2 21.8 2.1e-12 47.4 15.1 2.1 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Opi1 PF08618.5 OAP55528.1 - 1.7 7.4 7.8 2 7.2 5.4 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 SPX PF03105.14 OAP55528.1 - 2.7 7.7 11.9 6.3 6.4 8.3 1.6 1 1 0 1 1 1 0 SPX domain UcrQ PF02939.11 OAP55529.1 - 1.3e-28 98.6 0.0 1.6e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 OAP55530.1 - 4e-25 88.7 7.7 4e-25 88.7 5.3 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF2884 PF11101.3 OAP55530.1 - 0.014 14.8 0.7 0.025 13.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) WSC PF01822.14 OAP55531.1 - 2.6e-19 68.9 10.0 3.7e-19 68.4 6.9 1.2 1 0 0 1 1 1 1 WSC domain Prim_Zn_Ribbon PF08273.7 OAP55531.1 - 0.14 12.2 0.3 0.14 12.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Gamma-thionin PF00304.15 OAP55531.1 - 2.6 8.1 8.1 0.29 11.2 1.4 2.3 1 1 1 2 2 2 0 Gamma-thionin family DUF1996 PF09362.5 OAP55532.1 - 1.7e-91 306.0 0.7 2.4e-91 305.6 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 OAP55532.1 - 8e-19 67.3 11.6 8e-19 67.3 8.1 2.8 4 0 0 4 4 4 1 WSC domain BRCT PF00533.21 OAP55533.1 - 4.6e-08 33.0 0.0 1.2e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain STE2 PF02116.10 OAP55534.1 - 1.3e-08 34.2 14.5 1.9e-08 33.7 10.1 1.2 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR AOX PF01786.12 OAP55534.1 - 0.042 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Alternative oxidase Pex24p PF06398.6 OAP55535.1 - 6.2e-88 294.9 0.2 7.7e-88 294.6 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 OAP55535.1 - 0.0011 16.9 0.4 0.0096 13.8 0.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3292) Rod_cone_degen PF15201.1 OAP55535.1 - 0.045 13.6 0.1 0.41 10.5 0.0 2.6 2 0 0 2 2 2 0 Progressive rod-cone degeneration 2TM PF13239.1 OAP55535.1 - 0.074 13.1 0.4 0.24 11.5 0.3 1.8 1 0 0 1 1 1 0 2TM domain DUF639 PF04842.7 OAP55535.1 - 0.076 11.1 0.2 0.11 10.5 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Pkinase PF00069.20 OAP55536.1 - 4.1e-56 190.0 0.1 6.1e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP55536.1 - 2e-19 69.7 0.4 3.4e-19 68.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 OAP55536.1 - 0.042 13.5 2.5 0.075 12.7 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 OAP55536.1 - 0.15 11.3 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 OAP55536.1 - 0.17 11.4 0.3 0.37 10.3 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ank_2 PF12796.2 OAP55538.1 - 2.6e-23 82.1 0.4 2.3e-17 63.1 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAP55538.1 - 1.2e-16 59.5 10.7 2.2e-06 27.1 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 OAP55538.1 - 2.3e-16 58.2 5.1 4.9e-05 23.1 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 OAP55538.1 - 2e-14 53.6 1.5 9.8e-08 32.3 0.0 4.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP55538.1 - 5.6e-13 48.6 2.5 0.0014 18.8 0.0 4.2 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Zn_clus PF00172.13 OAP55538.1 - 4.7 7.1 15.7 8.3 6.4 10.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.18 OAP55540.1 - 7.1e-34 117.4 0.3 1.9e-33 116.0 0.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAP55540.1 - 0.006 17.0 0.1 3.3 8.2 0.0 2.8 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 OAP55540.1 - 0.14 12.0 0.1 0.6 9.9 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease adh_short PF00106.20 OAP55541.1 - 9e-24 84.2 0.1 1.3e-23 83.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP55541.1 - 8.3e-13 48.3 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP55541.1 - 5.7e-09 35.7 0.1 8.2e-08 31.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP55541.1 - 2.4e-06 26.6 0.0 3.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 OAP55541.1 - 1.7e-05 24.7 0.0 3.9e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 OAP55541.1 - 0.00022 20.0 0.0 0.00028 19.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 OAP55541.1 - 0.00076 19.1 0.2 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 OAP55541.1 - 0.0049 15.8 0.1 0.0098 14.8 0.1 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain ELFV_dehydrog PF00208.16 OAP55541.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Eno-Rase_NADH_b PF12242.3 OAP55541.1 - 0.011 15.4 0.4 0.024 14.4 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ldh_1_N PF00056.18 OAP55541.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 OAP55541.1 - 0.039 13.7 0.3 0.097 12.4 0.1 1.8 2 0 0 2 2 2 0 ThiF family DapB_N PF01113.15 OAP55541.1 - 0.039 13.8 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 OAP55541.1 - 0.048 13.6 0.3 0.15 12.0 0.2 1.8 2 0 0 2 2 2 0 NADH(P)-binding adh_short_C2 PF13561.1 OAP55542.1 - 3.3e-24 85.9 0.1 6e-23 81.8 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP55542.1 - 3.3e-17 62.9 0.1 2.6e-15 56.7 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP55542.1 - 1.7e-08 34.3 0.1 5e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 OAP55542.1 - 0.0039 15.9 0.1 0.0075 15.0 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 OAP55542.1 - 0.016 14.9 0.2 0.057 13.2 0.1 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 OAP55543.1 - 2.2e-30 105.3 0.8 4.2e-30 104.4 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55543.1 - 2.6e-06 27.2 19.1 4.4e-06 26.5 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP_endonuc_2 PF01261.19 OAP55544.1 - 3.9e-27 94.9 0.2 5.1e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.19 OAP55545.1 - 9.2e-60 202.4 21.8 1e-59 202.3 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55545.1 - 2.9e-22 78.8 47.3 7.4e-20 70.9 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP55545.1 - 0.0029 15.9 1.2 0.0029 15.9 0.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3439 PF11921.3 OAP55547.1 - 0.09 12.5 4.9 0.32 10.7 3.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cnd3 PF12719.2 OAP55548.1 - 2e-43 148.4 0.2 9.9e-42 142.9 0.0 2.6 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 OAP55548.1 - 2.1e-08 34.3 12.1 2e-05 24.7 1.1 5.6 3 2 3 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 OAP55548.1 - 3.5e-05 24.1 12.2 0.00096 19.5 0.8 6.4 6 1 0 6 6 6 1 HEAT-like repeat HEAT PF02985.17 OAP55548.1 - 0.0016 18.3 15.3 0.042 13.9 0.0 6.8 8 0 0 8 8 8 1 HEAT repeat DUF3449 PF11931.3 OAP55549.1 - 7.9e-69 231.1 0.1 3.1e-68 229.1 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 OAP55549.1 - 6.4e-14 51.1 0.9 1.5e-13 50.0 0.6 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 OAP55549.1 - 1.1e-09 38.0 2.0 7.1e-08 32.3 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAP55549.1 - 4.2e-07 29.9 5.7 6.3e-07 29.3 0.2 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 OAP55549.1 - 0.00074 19.5 0.4 0.035 14.2 0.0 2.9 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 OAP55549.1 - 0.028 14.7 3.5 0.23 11.8 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF951 PF06107.6 OAP55549.1 - 0.055 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Myb_CC_LHEQLE PF14379.1 OAP55549.1 - 0.23 11.0 6.4 6.1 6.5 4.4 2.6 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2 PF00096.21 OAP55549.1 - 0.38 11.1 4.4 0.95 9.9 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type SF-assemblin PF06705.6 OAP55549.1 - 3.1 6.8 8.6 6.4 5.8 0.4 3.1 3 0 0 3 3 3 0 SF-assemblin/beta giardin Arrestin_N PF00339.24 OAP55550.1 - 1e-08 35.1 0.0 6.3e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain RFC1 PF08519.7 OAP55551.1 - 1.9e-56 190.1 0.0 1.5e-55 187.2 0.0 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 OAP55551.1 - 2.2e-13 50.1 0.0 9.1e-13 48.1 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 OAP55551.1 - 7.8e-10 39.0 0.0 2.2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP55551.1 - 7.6e-07 29.3 0.0 2.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 OAP55551.1 - 2.8e-06 26.3 0.0 1.8e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 OAP55551.1 - 8.7e-05 23.3 2.4 0.00014 22.7 0.1 2.5 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 OAP55551.1 - 0.0015 18.4 0.1 0.0051 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP55551.1 - 0.002 17.8 0.1 0.0065 16.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAP55551.1 - 0.0025 17.8 0.0 0.016 15.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain PTCB-BRCT PF12738.2 OAP55551.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain AAA_18 PF13238.1 OAP55551.1 - 0.0077 16.5 0.1 0.0077 16.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 OAP55551.1 - 0.0082 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 OAP55551.1 - 0.051 13.2 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain PRD_Mga PF08270.6 OAP55551.1 - 0.079 12.2 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain AAA_14 PF13173.1 OAP55551.1 - 0.094 12.6 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAP55551.1 - 0.096 12.6 0.2 0.096 12.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF3112 PF11309.3 OAP55552.1 - 1.1e-48 165.0 11.4 1.6e-47 161.3 1.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Zn_clus PF00172.13 OAP55553.1 - 1.6e-05 24.7 10.4 2.5e-05 24.0 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 OAP55554.1 - 1.3e-25 89.7 33.1 1.9e-25 89.2 23.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LamB_YcsF PF03746.11 OAP55556.1 - 1.2e-59 201.4 0.0 2e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 LamB/YcsF family Amidase PF01425.16 OAP55557.1 - 2.4e-97 326.5 0.2 2.8e-97 326.3 0.1 1.0 1 0 0 1 1 1 1 Amidase Ribosomal_L16 PF00252.13 OAP55558.1 - 9.1e-29 99.8 0.1 1.3e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Gly_transf_sug PF04488.10 OAP55561.1 - 3.8e-08 33.6 0.0 2.2e-07 31.2 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 OAP55561.1 - 0.0086 14.6 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain CtaG_Cox11 PF04442.9 OAP55562.1 - 3.1e-59 199.1 0.0 3.7e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Redoxin PF08534.5 OAP55563.1 - 5.1e-15 55.3 0.0 5.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAP55563.1 - 2.8e-11 43.1 0.0 4.4e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family Pro-kuma_activ PF09286.6 OAP55564.1 - 1.2e-41 142.1 0.7 2.6e-41 141.0 0.1 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAP55564.1 - 1.5e-09 37.4 1.6 1.8e-08 33.8 1.1 2.3 1 1 0 1 1 1 1 Subtilase family DUF2863 PF11062.3 OAP55565.1 - 0.076 11.1 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) FOLN PF09289.5 OAP55565.1 - 0.24 11.2 0.7 0.4 10.5 0.5 1.3 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Fungal_trans PF04082.13 OAP55566.1 - 5.7e-10 38.5 2.2 1e-09 37.6 1.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP55566.1 - 2.2e-08 33.9 12.0 5.3e-05 23.3 2.1 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP55566.1 - 0.00029 20.9 8.8 0.00079 19.5 1.2 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP55566.1 - 0.00033 20.8 0.8 0.00033 20.8 0.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 OAP55566.1 - 0.0025 17.9 3.6 0.97 9.7 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAP55566.1 - 0.012 15.6 12.1 0.029 14.5 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 OAP55566.1 - 0.4 10.2 3.6 0.82 9.3 0.7 2.3 1 1 1 2 2 2 0 GAGA factor p450 PF00067.17 OAP55567.1 - 4.6e-72 243.0 0.0 5.5e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_N PF02771.11 OAP55569.1 - 2.6e-19 69.8 1.7 5.9e-19 68.7 0.0 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 OAP55569.1 - 4.8e-19 68.9 1.6 7.7e-19 68.2 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP55569.1 - 1.8e-06 27.3 0.0 4.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Grp1_Fun34_YaaH PF01184.14 OAP55570.1 - 2.7e-26 92.1 13.5 3.6e-26 91.7 9.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.11 OAP55571.1 - 3.1e-28 98.4 25.4 3.1e-28 98.4 17.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 OAP55571.1 - 0.003 17.5 1.2 0.003 17.5 0.9 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1228) DIOX_N PF14226.1 OAP55572.1 - 5.4e-31 107.5 0.0 8.7e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP55572.1 - 2.5e-24 85.4 0.0 4.6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.1 OAP55574.1 - 2.1e-08 33.9 0.0 0.00048 20.0 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAP55574.1 - 6.6e-07 28.8 0.5 0.0038 16.8 0.0 2.9 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 OAP55574.1 - 3.8e-05 23.2 0.7 0.00073 19.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAP55574.1 - 0.00015 21.1 1.5 0.0017 17.8 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP55574.1 - 0.00047 20.4 0.0 0.012 15.9 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAP55574.1 - 0.00051 19.8 0.7 0.0041 16.9 0.1 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP55574.1 - 0.00088 19.6 3.3 0.016 15.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP55574.1 - 0.00096 19.7 1.4 0.013 16.1 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP55574.1 - 0.0019 17.8 0.0 0.046 13.5 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP55574.1 - 0.0068 16.1 0.1 0.02 14.6 0.0 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAP55574.1 - 0.01 15.7 0.3 0.056 13.4 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP55574.1 - 0.013 15.9 0.1 0.45 11.0 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 OAP55574.1 - 0.061 13.4 0.1 0.32 11.1 0.0 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 OAP55575.1 - 3.6 7.7 16.9 1.3 9.1 1.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) PBP PF01161.15 OAP55576.1 - 1.5e-26 93.0 0.8 2.1e-26 92.4 0.6 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Dynamin_M PF01031.15 OAP55577.1 - 2.9e-114 380.8 0.0 6.9e-114 379.6 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 OAP55577.1 - 3e-55 186.5 1.2 3.8e-55 186.2 0.0 1.8 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 OAP55577.1 - 2.5e-32 110.6 0.8 6.2e-32 109.3 0.6 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 OAP55577.1 - 0.00069 19.5 0.5 0.0068 16.3 0.3 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAP55577.1 - 0.015 15.7 0.0 0.048 14.1 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein FLO_LFY PF01698.11 OAP55577.1 - 0.099 11.4 0.9 0.16 10.7 0.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein zf-CCHC_4 PF14392.1 OAP55577.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle GFA PF04828.9 OAP55580.1 - 1.6e-14 53.6 0.1 1.6e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme F-box-like PF12937.2 OAP55583.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 F-box-like GN3L_Grn1 PF08701.6 OAP55583.1 - 5.1 7.0 8.9 0.43 10.5 2.6 1.9 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase Ofd1_CTDD PF10637.4 OAP55586.1 - 1.9e-87 292.8 0.0 1.2e-79 267.2 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 OAP55586.1 - 1.8e-16 60.4 0.6 9.1e-16 58.2 0.1 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 OAP55586.1 - 0.0083 15.7 0.1 0.041 13.5 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.6 OAP55587.1 - 2.1e-10 39.9 0.3 4.3e-10 38.9 0.2 1.5 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 OAP55587.1 - 3.1e-08 33.1 0.1 4.4e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.14 OAP55587.1 - 0.11 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ABC_tran PF00005.22 OAP55588.1 - 3.7e-46 156.8 0.2 5.8e-22 78.4 0.0 3.0 4 0 0 4 4 2 2 ABC transporter ABC_tran_2 PF12848.2 OAP55588.1 - 1.3e-20 73.0 3.9 1.3e-20 73.0 2.7 3.2 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 OAP55588.1 - 1.1e-19 71.4 0.2 0.0021 18.0 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 OAP55588.1 - 6.1e-10 38.7 0.3 0.26 10.4 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAP55588.1 - 1.5e-08 34.0 0.4 0.003 17.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAP55588.1 - 1.2e-06 27.8 0.0 0.0018 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 OAP55588.1 - 1.5e-06 28.7 6.4 0.038 14.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.1 OAP55588.1 - 3.4e-06 27.3 1.8 0.051 13.8 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 OAP55588.1 - 5.6e-06 27.1 0.1 0.061 14.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 OAP55588.1 - 2.6e-05 24.2 0.4 0.3 11.0 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 OAP55588.1 - 2.7e-05 23.3 0.1 0.024 13.6 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain Miro PF08477.8 OAP55588.1 - 3.6e-05 24.2 0.0 0.13 12.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 OAP55588.1 - 3.6e-05 23.8 0.1 0.31 11.1 0.0 3.0 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 OAP55588.1 - 5.7e-05 23.0 0.0 0.1 12.5 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 OAP55588.1 - 6e-05 22.7 0.1 0.38 10.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 OAP55588.1 - 0.0002 21.5 0.1 0.67 10.1 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 OAP55588.1 - 0.00049 19.0 0.0 1.1 8.0 0.0 3.0 3 0 0 3 3 3 2 NB-ARC domain Arch_ATPase PF01637.13 OAP55588.1 - 0.00059 19.6 0.2 0.44 10.2 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 OAP55588.1 - 0.00067 19.6 0.0 0.55 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAP55588.1 - 0.00074 19.2 0.1 1.7 8.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAP55588.1 - 0.00084 19.2 0.0 0.51 10.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 OAP55588.1 - 0.0011 19.0 0.6 2.2 8.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase MobB PF03205.9 OAP55588.1 - 0.0013 18.4 0.2 0.027 14.1 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 OAP55588.1 - 0.0038 16.6 0.1 0.52 9.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAP55588.1 - 0.0058 16.0 1.2 1.1 8.6 0.4 2.6 2 0 0 2 2 2 1 AAA-like domain AAA_14 PF13173.1 OAP55588.1 - 0.0066 16.3 0.0 3.5 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 OAP55588.1 - 0.007 16.2 0.3 1.1 9.2 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DAP3 PF10236.4 OAP55588.1 - 0.0096 14.8 0.2 5.9 5.7 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF2813 PF11398.3 OAP55588.1 - 0.0099 14.9 0.5 4.1 6.3 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) PduV-EutP PF10662.4 OAP55588.1 - 0.015 14.8 0.6 2.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.4 OAP55588.1 - 0.025 13.1 0.0 4.9 5.6 0.0 3.1 3 1 0 3 3 3 0 Predicted ATPase of the ABC class Dynamin_N PF00350.18 OAP55588.1 - 0.039 13.7 0.6 12 5.7 0.0 3.5 2 1 1 3 3 3 0 Dynamin family ArgK PF03308.11 OAP55588.1 - 0.047 12.4 0.3 6.3 5.4 0.0 2.7 2 1 0 2 2 2 0 ArgK protein DUF815 PF05673.8 OAP55588.1 - 0.055 12.3 0.1 5.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) VirE PF05272.6 OAP55588.1 - 0.058 12.8 0.2 1.5 8.2 0.0 2.5 3 0 0 3 3 2 0 Virulence-associated protein E NTPase_1 PF03266.10 OAP55588.1 - 0.088 12.5 0.2 5.2 6.7 0.1 2.6 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.13 OAP55588.1 - 0.09 12.0 0.3 5.5 6.2 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_24 PF13479.1 OAP55588.1 - 0.1 12.1 5.0 4.6 6.7 0.0 3.8 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 OAP55588.1 - 0.2 11.4 2.3 17 5.0 0.0 3.3 3 1 1 4 4 3 0 Domain of unknown function DUF87 MCM PF00493.18 OAP55588.1 - 0.27 10.0 3.3 3.5 6.3 0.0 2.5 3 0 0 3 3 2 0 MCM2/3/5 family AAA_13 PF13166.1 OAP55588.1 - 5.8 5.2 11.2 8.3 4.7 0.0 4.1 4 1 0 4 4 4 0 AAA domain YadA_stalk PF05662.9 OAP55589.1 - 0.098 12.4 0.9 19 5.2 0.1 2.7 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin Sugar_tr PF00083.19 OAP55590.1 - 1.6e-80 270.9 22.6 1.8e-80 270.7 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55590.1 - 1.6e-21 76.3 36.6 4.6e-16 58.4 17.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP55591.1 - 1.4e-33 115.9 0.6 2.1e-33 115.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 OAP55592.1 - 2.1e-77 260.2 0.0 2.7e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP55592.1 - 1.1e-14 55.0 0.0 3.6e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 OAP55593.1 - 6.8e-07 28.4 2.4 1.2e-06 27.6 1.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.16 OAP55594.1 - 9.7e-09 35.0 0.0 1.3e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP55594.1 - 1.4e-06 28.4 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP55594.1 - 0.01 14.8 0.0 0.41 9.5 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein SGL PF08450.7 OAP55595.1 - 3.4e-10 39.7 0.4 1.4e-07 31.1 0.1 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Med9 PF07544.8 OAP55597.1 - 0.015 15.0 2.4 0.14 11.9 0.1 3.0 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DDE_3 PF13358.1 OAP55598.1 - 2.5e-14 53.2 0.7 2.5e-14 53.2 0.5 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 OAP55598.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain ArsC PF03960.10 OAP55598.1 - 0.048 13.7 0.0 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 ArsC family ANTH PF07651.11 OAP55602.1 - 6.2e-77 258.0 0.0 6.2e-77 258.0 0.0 3.3 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 OAP55602.1 - 5.4e-62 208.2 6.1 5.4e-62 208.2 4.2 6.1 4 1 3 7 7 7 1 I/LWEQ domain ENTH PF01417.15 OAP55602.1 - 3.5e-05 23.6 0.1 0.0003 20.6 0.0 2.7 2 0 0 2 2 2 1 ENTH domain Med15 PF09606.5 OAP55602.1 - 7.9 4.5 35.0 14 3.6 24.2 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal JmjC PF02373.17 OAP55609.1 - 1.8e-17 63.6 0.1 2.5e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Milton PF12448.3 OAP55611.1 - 0.016 15.3 0.3 0.03 14.5 0.2 1.4 1 0 0 1 1 1 0 Kinesin associated protein DUF3450 PF11932.3 OAP55611.1 - 0.033 13.4 2.1 0.046 12.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DJ-1_PfpI PF01965.19 OAP55612.1 - 0.056 12.9 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Uma2 PF05685.7 OAP55614.1 - 0.0059 15.9 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative restriction endonuclease adh_short PF00106.20 OAP55615.1 - 5.1e-24 85.0 8.3 8e-23 81.1 4.2 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55615.1 - 6.3e-19 68.7 3.5 1.4e-17 64.2 2.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55615.1 - 6.4e-11 42.2 0.8 1.2e-10 41.3 0.3 1.6 1 1 0 1 1 1 1 KR domain DUF853 PF05872.7 OAP55615.1 - 0.0086 14.4 0.7 0.14 10.5 0.0 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) F-box-like PF12937.2 OAP55616.1 - 0.00011 21.8 0.1 0.0003 20.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Peptidase_S24 PF00717.18 OAP55618.1 - 3.1e-09 36.3 0.0 1.9e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 OAP55618.1 - 6.1e-05 22.5 0.1 0.0013 18.2 0.0 2.6 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Acetyltransf_4 PF13420.1 OAP55619.1 - 2.8e-16 59.8 0.0 4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAP55619.1 - 6e-06 26.3 0.1 1.8e-05 24.8 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP55619.1 - 1e-05 25.5 0.0 4.4e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP55619.1 - 1.1e-05 25.3 0.1 4.7e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 OAP55619.1 - 4e-05 23.8 0.0 5.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP55619.1 - 0.00039 20.2 0.0 0.00094 19.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAP55619.1 - 0.0011 18.9 0.0 0.0028 17.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP55619.1 - 0.053 13.2 0.0 0.43 10.3 0.0 2.2 1 1 1 2 2 2 0 FR47-like protein VWA_3 PF13768.1 OAP55620.1 - 3e-29 101.7 0.0 6e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 OAP55620.1 - 3.9e-21 74.9 0.2 7.7e-21 73.9 0.1 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 OAP55620.1 - 8.1e-13 48.8 0.0 1.9e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 OAP55620.1 - 5.5e-09 35.3 0.1 1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 OAP55620.1 - 1.7e-07 31.1 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 OAP55620.1 - 0.0048 16.7 0.1 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 OAP55620.1 - 0.033 13.3 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CwfJ_C_1 PF04677.10 OAP55621.1 - 1.2e-15 57.2 0.0 1.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 OAP55621.1 - 4.9e-14 52.6 0.1 9.3e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Metallophos PF00149.23 OAP55621.1 - 0.072 12.4 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase DRIM PF07539.7 OAP55622.1 - 1.1e-27 96.1 0.0 2.8e-27 94.8 0.0 1.8 1 0 0 1 1 1 1 Down-regulated in metastasis DUF2435 PF10363.4 OAP55622.1 - 0.0086 15.9 0.2 0.12 12.3 0.0 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) G_glu_transpept PF01019.16 OAP55622.1 - 0.12 10.7 0.2 0.2 10.0 0.1 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase adh_short_C2 PF13561.1 OAP55623.1 - 2.8e-24 86.2 0.0 3.4e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP55623.1 - 1.6e-18 67.1 5.4 2.1e-18 66.8 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1702 PF08012.6 OAP55623.1 - 0.021 13.4 0.1 0.036 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) KR PF08659.5 OAP55623.1 - 0.097 12.3 5.1 0.29 10.7 3.6 1.9 1 1 0 1 1 1 0 KR domain 3HCDH_N PF02737.13 OAP55623.1 - 0.17 11.5 2.9 0.099 12.2 0.3 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 OAP55623.1 - 0.22 12.1 0.1 0.22 12.1 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain MAT1 PF06391.8 OAP55626.1 - 0.15 11.5 4.7 0.24 10.9 3.3 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 YlqD PF11068.3 OAP55626.1 - 6.3 6.8 4.6 11 6.0 3.2 1.3 1 0 0 1 1 1 0 YlqD protein PH_4 PF15404.1 OAP55629.1 - 5.1e-57 192.3 0.0 4.2e-56 189.4 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 OAP55629.1 - 8.1e-20 70.0 1.6 1.5e-19 69.2 0.1 2.2 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.24 OAP55629.1 - 6.2e-06 26.3 0.0 0.039 14.1 0.0 3.7 2 1 0 2 2 2 2 PH domain PH_6 PF15406.1 OAP55629.1 - 0.024 14.6 0.0 3.9 7.5 0.0 2.9 2 0 0 2 2 2 0 Pleckstrin homology domain GLTP PF08718.6 OAP55630.1 - 3.1e-38 131.1 0.0 4.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Macro PF01661.16 OAP55631.1 - 1.9e-37 127.7 0.0 2.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Macro domain Iso_dh PF00180.15 OAP55632.1 - 2.1e-77 260.4 0.0 2.5e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Isochorismatase PF00857.15 OAP55633.1 - 1.6e-35 122.5 0.0 1.8e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family ApbA PF02558.11 OAP55634.1 - 4.8e-27 94.2 0.0 6.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 OAP55634.1 - 5.7e-22 78.0 0.0 9.3e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Fringe PF02434.11 OAP55636.1 - 1.4e-06 27.7 0.3 1.3e-05 24.5 0.2 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 OAP55636.1 - 6.4e-05 22.6 0.0 0.015 14.8 0.0 2.5 1 1 1 2 2 2 2 Galactosyltransferase Glyco_transf_34 PF05637.7 OAP55636.1 - 0.00032 20.3 0.6 0.00055 19.5 0.4 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family PAN_1 PF00024.21 OAP55636.1 - 0.00097 18.8 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 OAP55636.1 - 0.0028 17.3 0.2 0.0067 16.1 0.2 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 OAP55636.1 - 0.01 15.4 0.6 0.022 14.3 0.4 1.5 1 0 0 1 1 1 0 PAN-like domain Lin-8 PF03353.10 OAP55636.1 - 6.3 5.9 16.9 0.21 10.8 6.1 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Baculo_PEP_C PF04513.7 OAP55637.1 - 0.0069 16.2 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.7 OAP55637.1 - 0.0077 15.7 3.3 0.8 9.3 1.1 2.8 2 1 1 3 3 3 2 Heat shock factor binding protein 1 Vps5 PF09325.5 OAP55637.1 - 0.023 13.9 0.0 0.14 11.4 0.1 1.9 2 0 0 2 2 2 0 Vps5 C terminal like Hemagglutinin PF00509.13 OAP55637.1 - 0.048 11.7 0.4 0.061 11.4 0.2 1.1 1 0 0 1 1 1 0 Haemagglutinin CDC37_M PF08565.6 OAP55637.1 - 0.073 12.5 0.1 0.12 11.8 0.1 1.4 1 1 0 1 1 1 0 Cdc37 Hsp90 binding domain Baculo_gp64 PF03273.8 OAP55637.1 - 0.093 10.8 0.1 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family MbeD_MobD PF04899.7 OAP55637.1 - 0.11 12.4 0.2 0.42 10.5 0.1 2.1 1 1 0 1 1 1 0 MbeD/MobD like Sulfate_transp PF00916.15 OAP55638.1 - 3.5e-50 170.5 7.8 5.6e-50 169.9 4.0 2.0 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 OAP55638.1 - 4.5e-32 109.5 0.5 4.5e-32 109.5 0.4 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 OAP55638.1 - 2e-18 65.9 0.0 3.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 OAP55638.1 - 0.0025 17.8 0.0 0.013 15.4 0.0 2.3 2 1 0 2 2 2 1 STAS domain Apc4_WD40 PF12894.2 OAP55638.1 - 0.064 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF912 PF06024.7 OAP55638.1 - 1.7 8.7 3.4 14 5.7 0.1 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Asp PF00026.18 OAP55639.1 - 2.5e-07 30.2 0.0 0.00079 18.7 0.0 3.5 3 1 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAP55639.1 - 0.027 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DSBA PF01323.15 OAP55640.1 - 1.8e-13 50.4 0.1 2.2e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF3289 PF11692.3 OAP55640.1 - 0.054 12.7 0.0 0.066 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) EIF_2_alpha PF07541.7 OAP55643.1 - 1.7e-38 130.8 0.0 3.2e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 OAP55643.1 - 7.8e-13 48.3 0.6 1.5e-12 47.4 0.4 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DUF3186 PF11382.3 OAP55643.1 - 0.082 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) IncA PF04156.9 OAP55645.1 - 8.4e-05 22.2 1.1 8.4e-05 22.2 0.7 1.8 2 0 0 2 2 2 1 IncA protein Baculo_PEP_C PF04513.7 OAP55645.1 - 0.00077 19.2 3.9 0.063 13.1 0.4 2.2 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 OAP55645.1 - 0.0011 18.8 1.8 0.0015 18.3 1.2 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6 PF04111.7 OAP55645.1 - 0.0019 17.3 0.1 0.0024 16.9 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF869 PF05911.6 OAP55645.1 - 0.0022 16.3 3.0 0.003 15.8 1.8 1.4 1 1 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF1515 PF07439.6 OAP55645.1 - 0.0024 17.6 0.5 0.0046 16.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) TMF_TATA_bd PF12325.3 OAP55645.1 - 0.0047 16.6 4.5 0.0067 16.1 1.3 2.0 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 OAP55645.1 - 0.0063 14.4 0.2 0.0075 14.1 0.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family IFT57 PF10498.4 OAP55645.1 - 0.0069 15.1 1.9 0.0084 14.8 1.3 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF4200 PF13863.1 OAP55645.1 - 0.012 15.5 2.0 0.018 14.9 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF342 PF03961.8 OAP55645.1 - 0.013 13.9 1.6 0.016 13.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SseC PF04888.7 OAP55645.1 - 0.014 14.7 3.6 0.014 14.7 2.5 1.4 2 0 0 2 2 1 0 Secretion system effector C (SseC) like family FH2 PF02181.18 OAP55645.1 - 0.016 14.1 2.4 0.021 13.7 1.7 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Apolipoprotein PF01442.13 OAP55645.1 - 0.017 14.6 0.4 0.023 14.1 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CENP-F_leu_zip PF10473.4 OAP55645.1 - 0.019 14.8 6.3 0.36 10.6 0.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 OAP55645.1 - 0.019 12.7 2.8 0.024 12.4 2.0 1.0 1 0 0 1 1 1 0 HOOK protein Mnd1 PF03962.10 OAP55645.1 - 0.019 14.6 1.7 0.027 14.1 1.2 1.1 1 0 0 1 1 1 0 Mnd1 family Spc7 PF08317.6 OAP55645.1 - 0.035 12.7 2.5 0.064 11.9 1.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.16 OAP55645.1 - 0.036 13.5 2.6 0.048 13.1 1.1 1.4 1 1 0 1 1 1 0 Intermediate filament protein Lact-deh-memb PF09330.6 OAP55645.1 - 0.037 13.4 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding DUF3584 PF12128.3 OAP55645.1 - 0.037 11.3 1.3 0.047 11.0 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WEMBL PF05701.6 OAP55645.1 - 0.039 12.4 3.0 0.051 12.0 2.1 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF3348 PF11828.3 OAP55645.1 - 0.04 13.3 2.2 0.063 12.6 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3348) RasGAP_C PF03836.10 OAP55645.1 - 0.042 13.5 1.9 0.073 12.7 1.3 1.5 1 1 0 1 1 1 0 RasGAP C-terminus DUF848 PF05852.6 OAP55645.1 - 0.054 13.3 4.2 0.5 10.2 1.1 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1664 PF07889.7 OAP55645.1 - 0.063 13.0 1.3 0.15 11.8 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HALZ PF02183.13 OAP55645.1 - 0.074 12.7 2.1 0.089 12.5 0.3 2.0 2 1 0 2 2 2 0 Homeobox associated leucine zipper TBPIP PF07106.8 OAP55645.1 - 0.087 12.3 5.8 0.54 9.7 2.2 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bacillus_HBL PF05791.6 OAP55645.1 - 0.11 11.8 5.0 0.31 10.3 3.0 1.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MscS_porin PF12795.2 OAP55645.1 - 0.11 11.7 3.7 0.29 10.4 2.5 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Seryl_tRNA_N PF02403.17 OAP55645.1 - 0.12 12.3 2.3 0.24 11.4 1.1 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1640 PF07798.6 OAP55645.1 - 0.14 12.1 4.7 0.69 9.9 3.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) COG2 PF06148.6 OAP55645.1 - 0.16 11.8 2.1 10 5.9 0.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 OAP55645.1 - 0.26 11.6 4.5 0.83 10.0 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Uds1 PF15456.1 OAP55645.1 - 0.29 11.1 3.2 1.1 9.3 0.4 2.2 1 1 1 2 2 2 0 Up-regulated During Septation FlaC_arch PF05377.6 OAP55645.1 - 0.29 11.0 4.9 0.11 12.3 0.7 2.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 OAP55645.1 - 0.38 10.6 4.7 2.7 7.8 3.4 1.8 1 1 0 1 1 1 0 Tropomyosin like Vps51 PF08700.6 OAP55645.1 - 0.39 10.5 4.0 0.66 9.8 1.6 2.2 1 1 2 3 3 3 0 Vps51/Vps67 Kinetocho_Slk19 PF12709.2 OAP55645.1 - 0.41 10.7 2.2 4.1 7.5 0.2 2.3 1 1 1 2 2 2 0 Central kinetochore-associated Lebercilin PF15619.1 OAP55645.1 - 0.41 10.0 4.5 0.58 9.5 3.1 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.16 OAP55645.1 - 0.43 10.5 6.5 0.13 12.2 0.6 2.7 2 1 1 3 3 3 0 bZIP transcription factor FlxA PF14282.1 OAP55645.1 - 0.57 10.1 5.9 0.43 10.5 1.8 2.1 1 1 1 2 2 2 0 FlxA-like protein Prefoldin_2 PF01920.15 OAP55645.1 - 0.59 9.9 3.7 4.4 7.1 1.6 2.6 1 1 1 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 OAP55645.1 - 0.68 9.6 4.6 2.4 7.9 3.2 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DASH_Dam1 PF08653.5 OAP55645.1 - 0.69 9.7 5.5 0.48 10.2 2.1 2.0 2 0 0 2 2 1 0 DASH complex subunit Dam1 BLOC1_2 PF10046.4 OAP55645.1 - 0.77 9.9 5.1 1.8 8.7 3.5 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.6 OAP55645.1 - 1 9.0 4.8 1.9 8.1 1.0 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.3 OAP55645.1 - 1.8 8.4 5.8 2.3 8.1 0.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding PKD_channel PF08016.7 OAP55646.1 - 1.8e-05 23.3 15.5 0.0021 16.5 6.3 2.3 2 0 0 2 2 2 2 Polycystin cation channel DUF843 PF05814.6 OAP55646.1 - 2.8 7.8 7.7 1.2 8.9 0.4 2.8 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) APH PF01636.18 OAP55647.1 - 2.9e-07 30.4 2.9 0.0095 15.6 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 OAP55647.1 - 3.4e-07 29.6 0.0 6.2e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 OAP55647.1 - 1.1e-05 24.6 0.1 0.00074 18.6 0.0 2.8 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 OAP55647.1 - 0.059 12.7 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.12 OAP55647.1 - 0.13 11.2 0.0 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Choline_kinase PF01633.15 OAP55647.1 - 0.2 11.1 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.16 OAP55648.1 - 7.4e-11 41.3 0.0 1.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family TRAP_alpha PF03896.11 OAP55648.1 - 0.28 10.1 5.6 0.41 9.5 3.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Merozoite_SPAM PF07133.6 OAP55648.1 - 1.2 9.0 14.4 1.9 8.3 10.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Rep_4 PF05797.6 OAP55648.1 - 1.5 7.4 4.3 2.1 6.9 3.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Paf1 PF03985.8 OAP55648.1 - 4.7 5.8 8.1 6.8 5.3 5.6 1.1 1 0 0 1 1 1 0 Paf1 RRN3 PF05327.6 OAP55648.1 - 5 5.1 5.0 6.5 4.7 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 OAP55648.1 - 5.4 5.3 10.7 7 4.9 7.4 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAP55648.1 - 6 6.0 10.4 8.7 5.5 7.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAP55648.1 - 6.6 4.6 6.3 8.8 4.2 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Maf1 PF09174.5 OAP55649.1 - 5.6e-56 189.2 0.0 1.2e-55 188.1 0.0 1.6 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 OAP55649.1 - 1.8e-52 176.8 1.9 2.7e-52 176.2 1.3 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TPR_MLP1_2 PF07926.7 OAP55650.1 - 7.4e-05 22.5 12.7 7.4e-05 22.5 8.8 4.9 4 1 1 5 5 5 3 TPR/MLP1/MLP2-like protein HOOK PF05622.7 OAP55650.1 - 9.3e-05 20.4 16.9 9.3e-05 20.4 11.7 3.1 1 1 2 3 3 3 2 HOOK protein Filament PF00038.16 OAP55650.1 - 0.00017 21.1 14.0 0.00017 21.1 9.7 4.1 2 1 2 4 4 4 1 Intermediate filament protein ADIP PF11559.3 OAP55650.1 - 0.0014 18.5 2.0 0.0014 18.5 1.4 4.6 3 2 2 5 5 5 1 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 OAP55650.1 - 0.0061 16.4 18.7 0.0061 16.4 13.0 4.4 3 1 1 5 5 5 1 Tropomyosin like Lectin_N PF03954.9 OAP55650.1 - 0.42 9.9 7.2 0.95 8.8 0.1 3.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Surfac_D-trimer PF09006.6 OAP55650.1 - 0.68 9.7 4.3 0.42 10.3 0.1 2.9 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Reo_sigmaC PF04582.7 OAP55650.1 - 0.71 8.9 9.6 0.53 9.4 3.3 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF4200 PF13863.1 OAP55650.1 - 0.82 9.6 60.3 0.052 13.5 7.2 5.5 5 1 1 6 6 6 0 Domain of unknown function (DUF4200) AbiH PF14253.1 OAP55650.1 - 1 8.8 4.7 3.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Cep57_CLD PF14073.1 OAP55650.1 - 7.6 6.3 44.8 16 5.2 13.7 4.8 1 1 2 3 3 3 0 Centrosome localisation domain of Cep57 Pkinase PF00069.20 OAP55653.1 - 6.9e-28 97.4 0.0 8.2e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP55653.1 - 3e-10 39.5 0.0 4.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP55653.1 - 0.015 15.0 0.0 0.25 11.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 OAP55653.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.11 OAP55653.1 - 0.096 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.20 OAP55654.1 - 5.4e-08 32.3 0.0 1.8e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP55654.1 - 8.3e-08 31.6 0.1 5.1e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Hydrolase PF00702.21 OAP55655.1 - 2.6e-22 80.2 0.0 1.1e-21 78.2 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAP55655.1 - 1.5e-21 77.4 0.0 2.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 OAP55655.1 - 2.2e-18 66.1 0.0 2.2e-17 62.8 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 OAP55655.1 - 3.9e-06 26.7 0.0 0.0001 22.1 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAP55655.1 - 5.9e-05 22.7 0.1 0.0017 17.9 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 OAP55655.1 - 0.056 12.7 0.3 0.36 10.0 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase tRNA-synt_1c PF00749.16 OAP55656.1 - 2.3e-102 341.8 0.0 3.6e-102 341.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 OAP55656.1 - 6.7e-34 117.0 0.3 2.9e-31 108.4 0.0 3.8 4 0 0 4 4 4 1 tRNA synthetases class I (E and Q), anti-codon binding domain FYVE PF01363.16 OAP55657.1 - 3e-05 23.8 3.7 0.00018 21.3 1.1 2.2 2 0 0 2 2 2 1 FYVE zinc finger zf-AN1 PF01428.11 OAP55657.1 - 5.2e-05 23.0 3.7 0.00011 21.9 2.6 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger zf-Di19 PF05605.7 OAP55657.1 - 0.01 15.9 0.1 0.01 15.9 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC5 PF06221.8 OAP55657.1 - 0.018 14.7 1.7 0.076 12.7 0.5 2.2 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2_2 PF12756.2 OAP55657.1 - 0.068 13.2 1.1 0.095 12.8 0.0 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3505 PF12013.3 OAP55657.1 - 0.11 12.7 1.6 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) Transp_Tc5_C PF04236.10 OAP55657.1 - 0.12 12.6 1.4 0.22 11.7 1.0 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain TnpV PF14198.1 OAP55657.1 - 0.14 12.0 0.8 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV IBR PF01485.16 OAP55657.1 - 0.39 10.6 3.4 0.31 10.9 1.0 1.8 2 0 0 2 2 2 0 IBR domain zf-BED PF02892.10 OAP55657.1 - 9.4 6.0 7.1 3.6 7.4 1.0 2.5 2 1 0 2 2 2 0 BED zinc finger FYVE PF01363.16 OAP55658.1 - 3.6e-16 58.8 4.7 6e-16 58.0 3.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger TerY-C PF15616.1 OAP55658.1 - 0.017 15.0 1.8 0.038 13.9 1.3 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain Rbsn PF11464.3 OAP55658.1 - 0.047 13.2 0.3 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 Rabenosyn Rab binding domain LHH PF14411.1 OAP55658.1 - 0.056 13.6 0.3 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH zf-Di19 PF05605.7 OAP55658.1 - 0.081 13.0 3.5 0.19 11.8 2.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-DHHC PF01529.15 OAP55658.1 - 0.19 11.0 2.5 0.17 11.2 0.5 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase DZR PF12773.2 OAP55658.1 - 0.7 9.7 7.3 5.9 6.7 3.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon bZIP_1 PF00170.16 OAP55658.1 - 1.5 8.8 6.9 5.2 7.1 0.0 3.2 4 0 0 4 4 4 0 bZIP transcription factor zinc-ribbons_6 PF07191.7 OAP55658.1 - 5.6 6.8 7.4 4.6 7.0 3.0 2.1 2 0 0 2 2 2 0 zinc-ribbons zf-B_box PF00643.19 OAP55658.1 - 7.7 6.4 9.0 4.9 7.1 2.8 2.3 2 0 0 2 2 2 0 B-box zinc finger CENP-L PF13092.1 OAP55659.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 ADH_N PF08240.7 OAP55661.1 - 0.00017 21.2 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CH PF00307.26 OAP55664.1 - 2.2e-06 27.6 0.0 0.041 13.9 0.0 3.3 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 OAP55664.1 - 0.00064 19.3 0.0 1.1 8.9 0.0 2.8 3 0 0 3 3 3 2 CAMSAP CH domain ERO1 PF04137.10 OAP55665.1 - 7.4e-133 442.9 0.0 8.8e-133 442.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fungal_trans_2 PF11951.3 OAP55666.1 - 3.2e-09 35.8 2.7 1.6e-05 23.7 0.3 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55666.1 - 0.0027 17.5 0.6 0.0053 16.6 0.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF946 PF06101.6 OAP55667.1 - 2.5e-14 52.1 2.9 1.1e-12 46.7 0.1 2.4 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) ISG65-75 PF11727.3 OAP55668.1 - 0.11 11.5 4.7 0.19 10.7 0.0 2.4 3 0 0 3 3 3 0 Invariant surface glycoprotein Pkinase PF00069.20 OAP55669.1 - 2.3e-36 125.2 0.0 3.7e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP55669.1 - 1.1e-19 70.6 0.0 1.5e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 OAP55669.1 - 2.8e-07 30.5 0.0 6.5e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 OAP55669.1 - 0.044 12.7 0.0 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 OAP55669.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family NIR_SIR PF01077.17 OAP55670.1 - 7.2e-32 109.9 0.0 1.3e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 OAP55670.1 - 6.1e-29 101.3 0.1 1.1e-28 100.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP55670.1 - 1.3e-14 54.3 4.7 3.5e-13 49.7 0.3 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 OAP55670.1 - 7.2e-14 51.5 2.4 1.8e-12 47.0 1.5 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 OAP55670.1 - 9.3e-10 37.9 0.0 2.9e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 OAP55670.1 - 2.9e-09 36.3 0.3 1e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 OAP55670.1 - 6.1e-09 35.5 0.0 3.2e-08 33.2 0.0 2.3 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAP55670.1 - 1.1e-07 32.1 0.0 0.00025 21.1 0.0 2.7 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP55670.1 - 0.00024 20.1 2.1 3.7 6.3 0.0 4.3 4 1 1 5 5 5 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP55670.1 - 0.00065 19.5 0.1 2.7 7.7 0.0 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 OAP55670.1 - 0.031 14.5 0.2 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 OAP55670.1 - 0.039 13.5 0.4 0.82 9.2 0.0 2.7 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 OAP55670.1 - 0.06 12.2 0.0 0.53 9.1 0.0 2.0 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 OAP55670.1 - 0.14 11.2 0.3 0.72 8.9 0.0 2.3 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 OAP55670.1 - 0.14 12.1 0.5 13 5.8 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 OAP55670.1 - 0.27 11.3 0.3 33 4.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Mo-co_dimer PF03404.11 OAP55671.1 - 7.1e-57 190.6 0.1 1.3e-56 189.8 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 OAP55671.1 - 5.1e-51 172.4 0.0 1.3e-50 171.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 OAP55671.1 - 1.4e-31 108.5 0.0 2.5e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAP55671.1 - 8.5e-28 97.1 0.0 1.8e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 OAP55671.1 - 1e-22 79.7 0.0 2.4e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 OAP55671.1 - 0.00065 19.6 0.0 0.062 13.2 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ribosomal_S8e PF01201.17 OAP55672.1 - 1.8e-37 128.4 2.1 1.2e-36 125.8 1.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e FHIPEP PF00771.15 OAP55672.1 - 0.18 10.0 1.4 0.23 9.7 1.0 1.1 1 0 0 1 1 1 0 FHIPEP family DUF2390 PF09523.5 OAP55672.1 - 1.7 8.8 6.0 3.5 7.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DSHCT PF08148.7 OAP55674.1 - 2.1e-59 199.7 0.4 4.7e-59 198.6 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 OAP55674.1 - 3e-21 75.6 0.0 6.9e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP55674.1 - 2.6e-06 27.1 0.0 7.7e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP55674.1 - 0.035 13.9 0.1 0.44 10.3 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.27 OAP55675.1 - 9.5e-12 44.3 8.2 0.00011 21.9 0.3 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Utp14 PF04615.8 OAP55675.1 - 1.1 7.3 27.4 2.1 6.4 19.0 1.4 1 0 0 1 1 1 0 Utp14 protein Peptidase_S15 PF02129.13 OAP55676.1 - 0.21 10.9 1.7 0.44 9.9 1.2 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Tom5 PF10642.4 OAP55676.1 - 0.96 9.1 0.0 0.96 9.1 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase PBP_sp32 PF07222.7 OAP55676.1 - 4 6.5 10.7 12 4.9 7.4 1.8 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1682 PF07946.9 OAP55676.1 - 9.1 5.0 10.6 21 3.8 7.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LMP PF04778.7 OAP55677.1 - 0.099 12.3 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 LMP repeated region tRNA-synt_2 PF00152.15 OAP55678.1 - 7e-78 261.7 0.0 1e-77 261.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 OAP55678.1 - 3.6e-20 72.0 1.7 4e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 OAP55678.1 - 1.4e-06 28.0 0.2 3.1e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SH3BGR PF04908.10 OAP55679.1 - 0.0012 18.7 0.0 0.017 15.0 0.0 2.7 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein GMC_oxred_N PF00732.14 OAP55680.1 - 7.3e-49 166.5 0.0 9.6e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP55680.1 - 6.3e-37 127.0 0.0 9.9e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP55680.1 - 7.2e-06 25.1 0.0 0.00069 18.6 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP55680.1 - 1.1e-05 24.4 0.0 0.079 11.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAP55680.1 - 5.8e-05 23.0 0.1 0.00035 20.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP55680.1 - 0.00021 20.3 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 OAP55680.1 - 0.03 12.9 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 OAP55680.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.17 OAP55681.1 - 5.5e-157 522.8 0.0 6.6e-157 522.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.15 OAP55682.1 - 1.2e-24 87.1 0.0 2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.16 OAP55683.1 - 3e-63 213.5 0.0 4.9e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 OAP55683.1 - 1.6e-06 28.0 0.1 1.7e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP55683.1 - 0.00012 22.1 0.0 0.027 14.5 0.0 2.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAP55683.1 - 0.00014 21.9 0.0 0.00035 20.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 OAP55683.1 - 0.0016 18.3 0.1 0.028 14.3 0.0 2.9 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 OAP55683.1 - 0.0028 17.2 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain NDT80_PhoG PF05224.7 OAP55684.1 - 6.6e-38 130.5 0.0 9.6e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family TPR_12 PF13424.1 OAP55685.1 - 1.2e-36 124.4 1.6 8.6e-12 44.8 0.0 4.8 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 OAP55685.1 - 2.1e-34 116.4 0.0 1.4e-09 37.5 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 OAP55685.1 - 1.2e-09 37.5 0.0 2.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 OAP55685.1 - 6.8e-07 29.0 0.0 2.8e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 NACHT domain TPR_17 PF13431.1 OAP55685.1 - 7.5e-06 25.7 0.1 3 8.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 OAP55685.1 - 0.00037 20.5 1.6 0.011 15.6 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain TPR_4 PF07721.9 OAP55685.1 - 0.00067 19.8 6.8 7.8 7.2 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat Rab5-bind PF09311.6 OAP55685.1 - 0.00073 19.4 2.1 0.41 10.5 0.1 2.6 1 1 1 2 2 2 2 Rabaptin-like protein TPR_7 PF13176.1 OAP55685.1 - 0.002 17.7 2.5 1.1 9.1 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP55685.1 - 0.0037 17.8 0.2 3.7 8.3 0.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 OAP55685.1 - 0.004 17.2 0.0 0.027 14.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain TPR_1 PF00515.23 OAP55685.1 - 0.0067 15.9 0.3 12 5.6 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 OAP55685.1 - 0.0085 15.8 0.0 0.52 9.9 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase TPR_19 PF14559.1 OAP55685.1 - 0.0094 16.2 1.8 2 8.7 0.2 4.0 3 2 1 4 4 4 1 Tetratricopeptide repeat Metallophos_3 PF14582.1 OAP55685.1 - 0.097 11.8 0.1 0.23 10.5 0.0 1.6 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily PNP_UDP_1 PF01048.15 OAP55686.1 - 4.5e-09 35.6 0.6 8.5e-08 31.4 0.4 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily FIVAR PF07554.8 OAP55688.1 - 0.34 11.1 5.6 1.9 8.8 3.9 2.4 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain CHASE3 PF05227.8 OAP55689.1 - 0.2 11.3 1.7 0.3 10.7 0.1 2.1 2 0 0 2 2 2 0 CHASE3 domain Lumazine_bd_2 PF12893.2 OAP55689.1 - 0.3 11.6 1.4 19 5.8 0.0 2.5 2 0 0 2 2 2 0 Putative lumazine-binding DUF2375 PF09558.5 OAP55690.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) Ribul_P_3_epim PF00834.14 OAP55691.1 - 1.8e-63 213.3 0.0 2.5e-62 209.5 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 OAP55691.1 - 0.015 14.8 0.1 0.03 13.8 0.0 1.6 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Phosphodiest PF01663.17 OAP55691.1 - 0.02 14.2 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase ThiG PF05690.9 OAP55691.1 - 0.022 13.8 0.1 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.19 OAP55691.1 - 0.025 13.9 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family LysR_substrate PF03466.15 OAP55691.1 - 0.039 13.0 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain PcrB PF01884.12 OAP55691.1 - 0.16 11.1 0.2 0.27 10.4 0.1 1.5 1 1 0 1 1 1 0 PcrB family EHN PF06441.7 OAP55692.1 - 3.3e-37 126.8 2.6 1e-36 125.2 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAP55692.1 - 6e-08 32.8 1.6 6e-08 32.8 1.1 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP55692.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acyltransferase PF01553.16 OAP55695.1 - 1.3e-26 92.6 0.0 2.5e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Gon7 PF08738.5 OAP55696.1 - 0.0067 16.3 0.8 0.02 14.8 0.6 1.9 1 1 0 1 1 1 1 Gon7 family Evr1_Alr PF04777.8 OAP55696.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Erv1 / Alr family DENN PF02141.16 OAP55697.1 - 1.2e-51 175.1 0.1 2.1e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 OAP55697.1 - 3.2e-15 55.9 0.0 6.8e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 OAP55697.1 - 1.7e-11 43.8 0.0 4.4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 OAP55697.1 - 7.1e-05 22.4 1.0 0.00012 21.6 0.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 OAP55697.1 - 0.0046 16.9 4.8 0.0085 16.1 3.3 1.5 1 0 0 1 1 1 1 C1-like domain DUF2730 PF10805.3 OAP55697.1 - 0.0075 15.9 0.5 0.021 14.5 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) C1_2 PF03107.11 OAP55697.1 - 0.014 15.4 4.9 0.025 14.6 3.4 1.4 1 0 0 1 1 1 0 C1 domain DUF1730 PF08331.5 OAP55697.1 - 0.099 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) TF_Zn_Ribbon PF08271.7 OAP55697.1 - 0.29 10.4 1.6 0.64 9.3 1.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding GAT PF03127.9 OAP55697.1 - 0.44 10.5 2.7 5.8 6.9 0.0 3.1 2 1 1 3 3 3 0 GAT domain DUF974 PF06159.8 OAP55698.1 - 8.2e-73 244.9 0.0 9.9e-73 244.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) MFS_1 PF07690.11 OAP55700.1 - 1.5e-43 148.8 35.0 1.5e-43 148.8 24.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP55700.1 - 2.1e-15 56.2 22.2 2.7e-13 49.2 8.5 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DASH_Dad2 PF08654.5 OAP55703.1 - 5.1e-29 100.2 0.1 1.2e-28 99.1 0.1 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 CENP-Q PF13094.1 OAP55703.1 - 0.038 14.0 1.1 0.038 14.0 0.8 1.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Duo1 PF08651.5 OAP55703.1 - 0.076 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 Shugoshin_N PF07558.6 OAP55704.1 - 3.6e-15 55.3 6.0 3.6e-15 55.3 4.2 1.9 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 OAP55704.1 - 2e-09 36.7 3.2 2e-09 36.7 2.2 3.7 4 0 0 4 4 4 1 Shugoshin C terminus Med21 PF11221.3 OAP55705.1 - 2.4e-35 121.5 4.2 1e-34 119.6 2.9 1.7 1 1 0 1 1 1 1 Subunit 21 of Mediator complex PAT1 PF09770.4 OAP55705.1 - 0.28 9.3 6.2 0.34 9.0 4.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med9 PF07544.8 OAP55705.1 - 0.51 10.1 3.9 0.17 11.5 0.3 2.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1183 PF06682.7 OAP55705.1 - 1.5 8.3 3.8 2.1 7.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Pkinase PF00069.20 OAP55706.1 - 3.9e-13 49.1 0.0 1.3e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP55706.1 - 4e-11 42.4 0.0 1.5e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAP55706.1 - 0.039 13.0 0.1 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.2 OAP55707.1 - 1.6e-130 425.7 0.0 5.9e-21 74.6 0.0 8.1 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 OAP55707.1 - 6.6e-106 341.2 0.0 5e-06 26.0 0.0 15.5 15 0 0 15 15 15 14 Ankyrin repeat Ank_4 PF13637.1 OAP55707.1 - 2.6e-100 327.2 0.0 7e-11 42.3 0.0 11.4 4 1 7 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP55707.1 - 1.2e-99 324.0 1.3 1.4e-08 34.7 0.0 11.7 1 1 13 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP55707.1 - 4.5e-97 308.1 0.0 0.00013 21.8 0.0 15.5 15 0 0 15 15 15 14 Ankyrin repeat NACHT PF05729.7 OAP55707.1 - 1.8e-08 34.2 0.1 4.7e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain DUF1654 PF07867.6 OAP55707.1 - 2.6e-06 26.7 10.6 7.7 5.9 0.0 10.0 6 1 6 12 12 12 2 Protein of unknown function (DUF1654) DUF3734 PF12536.3 OAP55707.1 - 1.4e-05 25.1 0.0 24 5.0 0.0 5.4 2 1 3 5 5 5 0 Patatin phospholipase AAA_16 PF13191.1 OAP55707.1 - 1.4e-05 25.1 0.0 3.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAP55707.1 - 0.00018 21.6 0.0 0.0023 18.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 OAP55707.1 - 0.0028 16.6 0.0 0.009 15.0 0.0 1.7 1 1 1 2 2 2 1 KAP family P-loop domain Abhydrolase_6 PF12697.2 OAP55707.1 - 0.0047 16.8 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.9 OAP55707.1 - 0.0099 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PGAP1 PF07819.8 OAP55707.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein AAA PF00004.24 OAP55707.1 - 0.056 13.6 0.1 0.7 10.0 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Thioesterase PF00975.15 OAP55707.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Cutinase PF01083.17 OAP55707.1 - 0.24 11.1 0.0 0.41 10.3 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF1282 PF06930.7 OAP55708.1 - 0.1 12.2 5.6 0.16 11.5 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) CobW_C PF07683.9 OAP55708.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain HECT PF00632.20 OAP55709.1 - 7.2e-86 288.2 0.0 1e-85 287.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 OAP55709.1 - 0.048 13.3 0.2 0.17 11.6 0.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Brevenin PF03032.10 OAP55709.1 - 0.37 10.6 2.8 0.93 9.3 2.0 1.6 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family Pkinase PF00069.20 OAP55710.1 - 8.3e-07 28.4 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 OAP55710.1 - 0.0027 17.4 0.0 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 OAP55711.1 - 2.8e-13 49.6 0.0 7.8e-13 48.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP55711.1 - 2.4e-11 43.2 0.0 1.5e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP55711.1 - 0.047 12.6 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Thymosin PF01290.15 OAP55711.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Thymosin beta-4 family FA_desaturase PF00487.19 OAP55712.1 - 0.017 14.5 2.2 0.028 13.8 1.5 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Tetraspannin PF00335.15 OAP55712.1 - 0.14 11.3 15.9 0.011 14.9 5.8 2.0 1 1 1 2 2 2 0 Tetraspanin family MARVEL PF01284.18 OAP55712.1 - 0.24 11.2 10.2 0.47 10.2 7.1 1.6 1 1 0 1 1 1 0 Membrane-associating domain DUF202 PF02656.10 OAP55712.1 - 2.3 8.4 9.2 11 6.2 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF2207 PF09972.4 OAP55712.1 - 2.4 6.6 6.3 3.9 5.9 0.1 2.3 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Abhydrolase_3 PF07859.8 OAP55714.1 - 1.3e-26 93.5 0.0 1.6e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAP55714.1 - 4e-21 75.0 0.0 4.7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 OAP55714.1 - 1.6e-05 24.9 0.2 2.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55714.1 - 8.5e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP55714.1 - 0.022 14.0 0.0 0.069 12.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 OAP55714.1 - 0.075 12.4 0.0 0.94 8.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase SPX PF03105.14 OAP55715.1 - 2.1e-47 162.1 1.1 3.5e-47 161.4 0.8 1.3 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 OAP55715.1 - 5.8e-28 97.9 44.3 8.5e-28 97.4 30.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 OAP55715.1 - 8.5e-17 60.7 48.7 2.6e-12 46.0 20.5 2.2 1 1 1 2 2 2 2 Citrate transporter PBP1_TM PF14812.1 OAP55715.1 - 0.026 14.8 1.6 0.081 13.2 1.1 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MEDS PF14417.1 OAP55715.1 - 0.093 11.7 0.6 0.36 9.8 0.1 1.9 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF3270 PF11674.3 OAP55715.1 - 1 9.4 11.9 0.15 12.1 0.4 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) DUF1980 PF09323.5 OAP55715.1 - 3.9 7.1 5.6 4.6 6.9 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) RTA1 PF04479.8 OAP55716.1 - 1.2e-47 162.2 8.9 1.7e-47 161.7 6.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF588 PF04535.7 OAP55716.1 - 0.0022 17.6 12.2 0.0033 16.9 2.5 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF588) Fungal_trans_2 PF11951.3 OAP55717.1 - 7.1e-05 21.5 1.2 0.028 13.0 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55717.1 - 0.00017 21.3 4.0 0.00051 19.8 2.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 OAP55719.1 - 1.4e-51 175.0 0.0 1.7e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peripla_BP_4 PF13407.1 OAP55719.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain Glu-tRNAGln PF02686.10 OAP55720.1 - 2e-06 27.5 0.7 3.7e-06 26.6 0.5 1.4 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.1 OAP55721.1 - 5.9e-112 373.4 19.6 6.7e-112 373.2 13.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 OAP55721.1 - 7e-07 29.0 17.9 0.0034 17.2 5.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAP55721.1 - 0.00033 20.2 11.2 1.4 8.8 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAP55721.1 - 0.0018 17.8 19.8 0.59 9.8 1.3 3.9 1 1 3 4 4 4 4 TPR repeat Foie-gras_1 PF11817.3 OAP55721.1 - 0.0041 16.6 6.7 0.013 14.9 4.6 1.8 1 1 0 1 1 1 1 Foie gras liver health family 1 Flag1_repress PF03614.8 OAP55721.1 - 0.038 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Repressor of phase-1 flagellin TPR_2 PF07719.12 OAP55721.1 - 0.4 10.7 18.9 7.8 6.6 0.6 5.7 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP55721.1 - 1.6 9.3 16.6 15 6.2 0.1 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP55721.1 - 3.5 7.4 9.9 13 5.5 0.3 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.22 OAP55722.1 - 1.2e-35 123.1 0.0 2.3e-35 122.1 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.22 OAP55723.1 - 1.2e-15 56.5 2.6 2.7e-15 55.4 1.8 1.7 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 OAP55723.1 - 0.031 13.5 0.2 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Cep57_CLD_2 PF14197.1 OAP55723.1 - 0.47 10.4 8.2 1.5 8.8 5.7 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 SPX PF03105.14 OAP55723.1 - 0.49 10.1 8.7 0.75 9.5 6.0 1.3 1 0 0 1 1 1 0 SPX domain bZIP_2 PF07716.10 OAP55723.1 - 1.5 8.7 8.2 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Basic region leucine zipper AMP-binding PF00501.23 OAP55725.1 - 1.5e-77 260.7 0.0 1.9e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP55725.1 - 4e-17 62.9 0.3 7.5e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Na_Ca_ex PF01699.19 OAP55727.1 - 1.1e-19 70.3 11.6 1.2e-11 44.4 4.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Phage_antitermQ PF06530.7 OAP55727.1 - 0.048 13.2 0.0 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Phage antitermination protein Q Rgp1 PF08737.5 OAP55728.1 - 2e-104 349.9 0.0 3.8e-104 349.0 0.0 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 OAP55728.1 - 0.0027 17.5 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Diphthamide_syn PF01866.12 OAP55729.1 - 1.2e-113 379.3 0.0 1.5e-113 379.1 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF1751 PF08551.5 OAP55730.1 - 0.00011 22.5 2.4 0.00019 21.7 1.7 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 OAP55730.1 - 0.00083 19.3 1.5 0.0016 18.4 1.1 1.4 1 0 0 1 1 1 1 Rhomboid family CENP-T PF15511.1 OAP55730.1 - 0.0025 17.1 15.0 0.0026 17.0 10.4 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T RNA_polI_A34 PF08208.6 OAP55730.1 - 0.043 13.4 20.1 0.063 12.9 13.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 OAP55730.1 - 0.28 10.9 12.7 0.065 13.0 6.7 1.6 2 0 0 2 2 2 0 DDHD domain DUF2722 PF10846.3 OAP55730.1 - 2.8 6.8 12.5 0.21 10.5 5.6 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Zip PF02535.17 OAP55730.1 - 4.1 6.3 10.7 7.1 5.5 7.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 OAP55730.1 - 5.4 6.3 33.4 8.4 5.6 23.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_3_Rpc31 PF11705.3 OAP55730.1 - 9.9 6.0 36.0 15 5.3 25.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIH_BTF_p62_N PF08567.6 OAP55731.1 - 3.9e-23 80.9 0.1 1.1e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 OAP55731.1 - 5e-22 77.4 0.7 1.1e-10 41.1 0.1 3.0 2 1 0 2 2 2 2 BSD domain PTB PF08416.8 OAP55731.1 - 0.054 13.4 0.0 3.8 7.4 0.0 3.0 3 0 0 3 3 3 0 Phosphotyrosine-binding domain FTA2 PF13095.1 OAP55732.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.11 OAP55733.1 - 2.5e-26 92.2 35.8 2.5e-26 92.2 24.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Tmemb_18A PF09771.4 OAP55733.1 - 0.083 12.8 0.4 4.8 7.1 0.0 2.9 2 0 0 2 2 2 0 Transmembrane protein 188 DUF1469 PF07332.6 OAP55733.1 - 0.37 10.5 0.1 0.37 10.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) adh_short_C2 PF13561.1 OAP55734.1 - 5e-29 101.7 0.1 5.7e-29 101.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP55734.1 - 1.4e-19 70.6 3.7 2.1e-19 70.0 2.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 OAP55734.1 - 0.034 13.7 1.7 0.058 13.0 0.8 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VWA_2 PF13519.1 OAP55735.1 - 0.0002 21.5 0.0 0.00074 19.6 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 OAP55735.1 - 0.00086 19.1 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF605 PF04652.11 OAP55735.1 - 0.28 10.5 18.0 0.43 9.9 12.5 1.2 1 0 0 1 1 1 0 Vta1 like Fungal_lectin PF07938.7 OAP55737.1 - 3.3e-39 135.0 9.3 5e-36 124.5 6.0 2.4 1 1 1 2 2 2 2 Fungal fucose-specific lectin HC2 PF07382.6 OAP55737.1 - 4.5e-06 26.6 21.0 7.1e-06 26.0 14.5 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 HNH_2 PF13391.1 OAP55738.1 - 1.7e-09 37.3 0.1 1.7e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease adh_short_C2 PF13561.1 OAP55739.1 - 2.4e-28 99.5 0.1 2.8e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP55739.1 - 6.2e-21 75.0 0.5 8e-21 74.6 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_26 PF13659.1 OAP55739.1 - 0.0028 17.6 0.2 0.0037 17.2 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain KR PF08659.5 OAP55739.1 - 0.0076 15.9 0.2 0.012 15.2 0.2 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_11 PF08241.7 OAP55739.1 - 0.08 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M16_C PF05193.16 OAP55740.1 - 4.6e-20 72.0 0.0 2.3e-15 56.7 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 OAP55740.1 - 2.7e-05 23.9 0.2 9.4e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Ank_2 PF12796.2 OAP55741.1 - 7.9e-35 119.0 0.3 1.9e-14 53.7 0.0 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP55741.1 - 3e-28 97.6 0.3 1.7e-06 28.3 0.0 5.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP55741.1 - 3.5e-26 90.6 1.6 3.5e-07 30.2 0.0 6.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 OAP55741.1 - 3.7e-25 86.4 4.9 7.4e-05 22.3 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 OAP55741.1 - 5.1e-19 66.4 2.4 0.02 15.1 0.0 7.7 7 0 0 7 7 7 4 Ankyrin repeat NACHT PF05729.7 OAP55741.1 - 3.5e-09 36.5 0.1 7.9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 OAP55741.1 - 9.8e-05 22.5 0.0 0.00032 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP55741.1 - 0.03 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF4287 PF14117.1 OAP55741.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Pkinase PF00069.20 OAP55742.1 - 4.3e-28 98.1 0.0 9.3e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP55742.1 - 1.5e-14 53.6 0.0 3.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HeLo PF14479.1 OAP55743.1 - 7.6e-06 25.8 0.2 1.5e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Sod_Fe_C PF02777.13 OAP55744.1 - 1.5e-34 118.0 0.9 2.9e-34 117.0 0.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAP55744.1 - 7.4e-30 103.0 2.3 7.9e-30 102.9 0.8 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain WD40 PF00400.27 OAP55747.1 - 4.9e-31 105.4 23.6 3.9e-07 29.7 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 OAP55747.1 - 3.9e-18 65.2 0.1 6.5e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Dsl1_C PF11989.3 OAP55748.1 - 0.00013 21.2 0.0 0.00013 21.2 0.0 2.8 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Fib_alpha PF08702.5 OAP55748.1 - 8.3 6.5 11.9 2.5 8.2 4.7 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AA_permease PF00324.16 OAP55749.1 - 1.3e-140 468.9 33.9 1.6e-140 468.6 23.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP55749.1 - 1.3e-38 132.6 33.7 1.7e-38 132.2 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 OAP55749.1 - 0.13 10.6 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Methyltransf_16 PF10294.4 OAP55751.1 - 1.1e-44 151.9 0.0 1.9e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 OAP55751.1 - 0.00042 20.0 0.0 0.00066 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP55751.1 - 0.0005 20.0 0.1 0.003 17.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP55751.1 - 0.001 19.6 0.1 0.0019 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAP55751.1 - 0.0025 17.3 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 OAP55751.1 - 0.04 13.3 0.1 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Orn_Arg_deC_N PF02784.11 OAP55752.1 - 9.7e-76 254.2 0.0 1.4e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 OAP55752.1 - 5.4e-32 109.9 0.0 1.1e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 OAP55752.1 - 0.00098 18.4 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF3425 PF11905.3 OAP55753.1 - 2e-28 98.9 0.0 4.7e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FTO_CTD PF12934.2 OAP55753.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 FTO C-terminal domain adh_short PF00106.20 OAP55754.1 - 1.2e-18 67.6 0.1 1.9e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP55754.1 - 1.2e-09 38.1 0.1 1.8e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP55754.1 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP55754.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP55754.1 - 0.0078 16.2 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding cobW PF02492.14 OAP55755.1 - 7.9e-38 129.6 0.0 1.4e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 OAP55755.1 - 0.001 18.8 0.0 0.0042 16.7 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 OAP55755.1 - 0.0076 15.9 0.1 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 OAP55755.1 - 0.029 13.9 0.2 0.82 9.2 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 OAP55755.1 - 0.053 13.6 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAP55755.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.13 OAP55755.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 OAP55755.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1470 PF07336.6 OAP55755.1 - 0.13 12.5 0.0 2.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) DSBA PF01323.15 OAP55756.1 - 1.6e-13 50.6 0.0 1.9e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain WD40 PF00400.27 OAP55758.1 - 5.7e-87 282.7 35.8 1e-14 53.7 0.6 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 OAP55758.1 - 4e-11 41.7 13.5 0.16 10.0 0.1 6.2 1 1 4 5 5 5 5 Nucleoporin Nup120/160 NACHT PF05729.7 OAP55758.1 - 2.1e-09 37.2 0.0 4.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 OAP55758.1 - 2.2e-06 27.2 10.8 18 5.0 0.1 6.8 7 0 0 7 7 6 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 OAP55758.1 - 1.2e-05 25.4 1.5 2.5e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAP55758.1 - 0.014 15.5 0.3 0.71 10.0 0.0 3.2 4 0 0 4 4 3 0 AAA domain APS_kinase PF01583.15 OAP55758.1 - 0.02 14.5 0.1 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.24 OAP55758.1 - 0.025 14.7 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HTH_20 PF12840.2 OAP55758.1 - 0.035 13.8 0.1 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_17 PF13207.1 OAP55758.1 - 0.05 14.4 0.1 0.4 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAP55758.1 - 0.076 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 OAP55758.1 - 0.082 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 OAP55758.1 - 0.097 11.5 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 OAP55758.1 - 0.12 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 OAP55758.1 - 0.15 11.7 0.0 1.2 8.8 0.0 2.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 OAP55758.1 - 0.17 11.3 0.1 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Proteasome_A_N PF10584.4 OAP55758.1 - 1.2 8.5 16.4 86 2.5 0.0 6.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature CorA PF01544.13 OAP55761.1 - 0.00028 20.0 0.2 0.0029 16.7 0.0 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein CFEM PF05730.6 OAP55762.1 - 9.2e-14 51.0 11.9 1.5e-13 50.3 8.2 1.4 1 0 0 1 1 1 1 CFEM domain YebO PF13974.1 OAP55762.1 - 0.017 14.9 1.0 0.017 14.9 0.7 2.7 3 0 0 3 3 3 0 YebO-like protein Gamma-thionin PF00304.15 OAP55762.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.8 2 0 0 2 2 2 0 Gamma-thionin family DUF2985 PF11204.3 OAP55763.1 - 5.9e-29 99.6 4.5 2.8e-28 97.5 3.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF4560 PF15118.1 OAP55763.1 - 0.05 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4560) HTH_Tnp_Tc5 PF03221.11 OAP55765.1 - 1.3e-11 44.1 0.0 2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 OAP55765.1 - 6.3e-08 32.0 0.9 1.1e-07 31.2 0.6 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain NUMOD1 PF07453.8 OAP55765.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain HTH_28 PF13518.1 OAP55765.1 - 0.12 12.4 0.1 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain R3H PF01424.17 OAP55766.1 - 3.2e-13 49.1 0.0 6.3e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 R3H domain Proteasome PF00227.21 OAP55767.1 - 2.7e-28 98.5 0.0 3.3e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2404 PF10296.4 OAP55768.1 - 3.4e-29 100.8 0.0 5.9e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 OAP55768.1 - 0.043 14.0 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 PH domain Sugar_tr PF00083.19 OAP55769.1 - 1.1e-84 284.6 30.3 1.3e-84 284.3 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55769.1 - 1.4e-15 56.8 49.1 2.1e-09 36.5 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.18 OAP55770.1 - 2.4e-17 63.4 1.8 4.2e-17 62.6 1.3 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP55770.1 - 0.00075 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 OAP55770.1 - 0.0022 17.2 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain PknH_C PF14032.1 OAP55770.1 - 0.14 11.7 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 PknH-like extracellular domain RIO1 PF01163.17 OAP55770.1 - 0.16 11.3 0.0 1.9 7.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family adh_short PF00106.20 OAP55771.1 - 1.1e-23 83.9 1.8 1.6e-23 83.4 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55771.1 - 7.2e-21 75.0 0.6 8.4e-21 74.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55771.1 - 1.4e-13 50.8 0.5 1.9e-13 50.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP55771.1 - 2.3e-05 23.9 0.1 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAP55771.1 - 0.016 14.8 0.3 0.029 14.0 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 OAP55771.1 - 0.073 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase YjeF_N PF03853.10 OAP55771.1 - 0.075 12.6 0.9 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus ApbA PF02558.11 OAP55771.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_18 PF12847.2 OAP55771.1 - 0.086 13.4 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Transaldolase PF00923.14 OAP55772.1 - 6e-28 97.8 0.0 7.7e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Transaldolase DNA_pol_B PF00136.16 OAP55773.1 - 4.2e-94 315.9 0.0 6.6e-94 315.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 OAP55773.1 - 9e-20 70.7 0.0 2.3e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain Fungal_trans PF04082.13 OAP55773.1 - 1.2e-10 40.7 0.6 2e-10 39.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C4pol PF14260.1 OAP55773.1 - 5.4e-06 26.3 2.5 1.3e-05 25.1 1.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.3 OAP55774.1 - 5.2e-60 203.1 20.1 5.2e-60 203.1 13.9 2.1 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 OAP55774.1 - 0.026 14.1 0.7 0.05 13.2 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle NFRKB_winged PF14465.1 OAP55776.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.6 1 1 0 1 1 1 0 NFRKB Winged Helix-like Arb1 PF09692.5 OAP55776.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Uds1 PF15456.1 OAP55778.1 - 1e-41 141.7 6.9 1e-41 141.7 4.8 5.7 5 1 1 6 6 6 2 Up-regulated During Septation DUF4618 PF15397.1 OAP55778.1 - 0.00085 18.7 22.1 0.00085 18.7 15.3 5.0 4 1 0 5 5 5 1 Domain of unknown function (DUF4618) HR1 PF02185.11 OAP55778.1 - 0.0016 18.1 0.7 0.0016 18.1 0.5 8.5 6 3 3 9 9 9 3 Hr1 repeat APG6 PF04111.7 OAP55778.1 - 0.0044 16.1 15.8 0.0044 16.1 10.9 6.3 2 2 5 7 7 7 2 Autophagy protein Apg6 NPV_P10 PF05531.7 OAP55778.1 - 3.4 7.9 32.8 1.9 8.8 0.3 7.0 5 2 0 6 6 6 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 OAP55779.1 - 1.8e-30 105.8 30.6 3.1e-30 105.0 21.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAP55779.1 - 1.8e-06 26.6 1.9 1.8e-06 26.6 1.3 2.7 2 1 1 3 3 3 1 MFS/sugar transport protein Sugar_tr PF00083.19 OAP55779.1 - 5.2e-06 25.2 21.0 0.0005 18.7 4.1 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter UCR_hinge PF02320.11 OAP55780.1 - 4.8e-14 52.0 5.2 8.1e-14 51.3 3.6 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF4211 PF13926.1 OAP55780.1 - 0.11 11.9 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) CobT PF06213.7 OAP55780.1 - 0.58 9.2 22.5 0.83 8.7 15.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 OAP55780.1 - 0.62 7.9 25.6 0.69 7.7 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAP55780.1 - 1.9 6.4 15.6 2.1 6.2 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 OAP55780.1 - 1.9 7.4 18.6 2 7.3 12.9 1.1 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.3 OAP55780.1 - 3.7 6.0 7.2 4 5.9 5.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.7 OAP55780.1 - 4.8 6.3 26.2 5.3 6.2 18.2 1.1 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 OAP55780.1 - 6.6 5.8 18.0 7.2 5.7 12.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 OAP55780.1 - 8.5 4.7 28.8 10 4.4 20.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF2201_N PF13203.1 OAP55780.1 - 9.8 5.2 9.4 12 4.9 6.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain WWbp PF10349.4 OAP55781.1 - 3.2e-16 60.2 2.6 5.1e-16 59.5 1.8 1.3 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 OAP55781.1 - 0.0025 17.5 0.0 0.0093 15.7 0.0 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 OAP55781.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Glyoxalase_2 PF12681.2 OAP55782.1 - 4.8e-09 36.7 0.0 6.1e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP55782.1 - 0.028 14.3 0.0 0.83 9.6 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NAD_binding_1 PF00175.16 OAP55783.1 - 3.2e-13 50.1 0.0 7.9e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 OAP55783.1 - 3.7e-09 36.6 0.0 6.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 OAP55783.1 - 7e-08 32.7 0.0 3.5e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 OAP55783.1 - 4.6e-06 26.6 0.0 1.2e-05 25.2 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 OAP55783.1 - 4.3e-05 23.2 0.2 8e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Protoglobin DUF3201 PF11447.3 OAP55783.1 - 0.13 11.6 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) MFS_1 PF07690.11 OAP55784.1 - 4.1e-25 88.2 20.5 4.1e-25 88.2 14.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP55784.1 - 1.3e-08 33.8 1.8 1.3e-08 33.8 1.2 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 OAP55784.1 - 6.1e-06 24.7 1.6 6.1e-06 24.7 1.1 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3139 PF11337.3 OAP55784.1 - 0.056 13.7 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Sugar_tr PF00083.19 OAP55785.1 - 1.2e-13 50.4 3.5 1.5e-13 50.1 2.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Arrestin_C PF02752.17 OAP55786.1 - 4.1e-11 43.1 0.8 4.5e-09 36.5 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAP55786.1 - 6.6e-08 32.4 0.0 2.4e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 OAP55786.1 - 0.024 14.1 0.5 0.46 9.9 0.0 2.9 2 2 2 4 4 4 0 Arrestin_N terminal like HOOK PF05622.7 OAP55788.1 - 0.0061 14.4 1.6 0.0072 14.2 1.1 1.0 1 0 0 1 1 1 1 HOOK protein Anthrax-tox_M PF09156.5 OAP55788.1 - 0.13 11.3 0.6 0.15 11.1 0.4 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain DUF4164 PF13747.1 OAP55788.1 - 0.19 11.9 3.6 0.31 11.1 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) adh_short PF00106.20 OAP55791.1 - 1.6e-14 54.2 0.0 2.7e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP55791.1 - 1.7e-05 24.5 0.0 3.5e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP55791.1 - 4.6e-05 23.2 0.0 6.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF460 PF04312.8 OAP55791.1 - 0.002 17.6 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF460) TPR_12 PF13424.1 OAP55793.1 - 1.2e-60 201.3 27.8 2.7e-12 46.4 0.3 5.4 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 OAP55793.1 - 1.2e-47 158.4 27.9 1.4e-07 31.1 0.2 8.7 8 0 0 8 8 8 7 Tetratricopeptide repeat Patatin PF01734.17 OAP55793.1 - 5.2e-24 85.3 0.0 1.5e-23 83.7 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_14 PF13428.1 OAP55793.1 - 2e-18 65.1 21.0 0.0019 18.6 0.6 7.9 3 1 5 8 8 6 5 Tetratricopeptide repeat TPR_20 PF14561.1 OAP55793.1 - 5.8e-16 58.3 13.5 0.076 13.1 0.1 7.1 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 OAP55793.1 - 9e-14 50.2 14.5 0.14 12.1 0.1 7.7 9 0 0 9 9 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 OAP55793.1 - 1.5e-13 50.1 2.3 0.013 15.1 0.1 4.7 1 1 3 5 5 5 5 TPR repeat Apc3 PF12895.2 OAP55793.1 - 1.8e-13 50.4 2.5 0.0047 17.0 0.1 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 OAP55793.1 - 3.3e-13 49.7 10.5 0.0053 17.0 0.1 5.7 1 1 6 7 7 7 6 Tetratricopeptide repeat NB-ARC PF00931.17 OAP55793.1 - 3.8e-13 48.9 0.0 9.8e-13 47.5 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_16 PF13432.1 OAP55793.1 - 1.1e-12 48.2 18.3 0.00014 22.4 0.6 5.9 2 1 6 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.1 OAP55793.1 - 3.4e-11 42.8 7.7 2.1 9.0 0.1 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat PPR PF01535.15 OAP55793.1 - 5.9e-09 35.3 0.0 4.7 7.4 0.0 6.2 6 0 0 6 6 6 1 PPR repeat AAA_22 PF13401.1 OAP55793.1 - 9.6e-09 35.4 0.0 4e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_8 PF13181.1 OAP55793.1 - 1.6e-08 33.7 0.1 19 5.3 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP55793.1 - 1.6e-08 33.6 16.5 1.3 8.9 0.1 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 OAP55793.1 - 1e-07 31.5 3.6 11 6.4 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_16 PF13191.1 OAP55793.1 - 2.6e-07 30.8 0.1 2.6e-07 30.8 0.1 2.8 2 1 0 2 2 1 1 AAA ATPase domain TPR_4 PF07721.9 OAP55793.1 - 4.1e-05 23.6 49.7 0.88 10.1 0.4 9.1 10 0 0 10 10 8 6 Tetratricopeptide repeat PPR_1 PF12854.2 OAP55793.1 - 0.0005 19.4 9.4 11 5.6 0.1 5.9 6 0 0 6 6 6 0 PPR repeat TPR_1 PF00515.23 OAP55793.1 - 0.0008 18.9 11.1 18 5.1 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat SRP54 PF00448.17 OAP55793.1 - 0.00088 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PPR_2 PF13041.1 OAP55793.1 - 0.0018 18.2 0.1 67 3.5 0.0 5.5 6 0 0 6 6 6 0 PPR repeat family NACHT PF05729.7 OAP55793.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SNAP PF14938.1 OAP55793.1 - 0.031 13.4 0.4 2.3 7.3 0.0 2.6 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP AAA_5 PF07728.9 OAP55793.1 - 0.052 13.2 0.5 0.63 9.7 0.0 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) FAD_binding_3 PF01494.14 OAP55795.1 - 4.5e-18 65.4 3.5 5.1e-17 61.9 2.4 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP55795.1 - 0.00026 20.9 0.3 0.00059 19.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 OAP55795.1 - 0.001 17.9 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 OAP55795.1 - 0.022 13.6 0.8 0.036 12.9 0.6 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4520 PF15016.1 OAP55795.1 - 0.058 12.9 0.0 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Pyr_redox_2 PF07992.9 OAP55795.1 - 0.08 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SBP_bac_3 PF00497.15 OAP55795.1 - 0.14 11.4 0.0 0.41 9.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Glyco_hydro_28 PF00295.12 OAP55796.1 - 9.2e-43 146.4 14.9 7e-42 143.5 10.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Amidase PF01425.16 OAP55797.1 - 7.6e-78 262.3 0.0 9e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.16 OAP55798.1 - 1.2e-12 47.4 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.13 OAP55799.1 - 4.1e-27 94.6 0.4 6.3e-27 94.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55799.1 - 9.4e-09 35.0 7.9 1.7e-08 34.1 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 OAP55800.1 - 2.7e-94 316.2 35.1 3.1e-94 316.0 24.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 OAP55801.1 - 2.2e-44 151.6 40.8 2e-43 148.4 29.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP55801.1 - 8e-19 67.2 8.0 1.5e-18 66.4 5.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAP55801.1 - 3.7e-17 62.0 1.7 3.7e-17 62.0 1.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter AA_permease_2 PF13520.1 OAP55802.1 - 2.6e-51 174.5 51.0 3.1e-51 174.2 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP55802.1 - 1.7e-23 82.7 45.7 2.4e-23 82.2 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease KLRAQ PF10205.4 OAP55804.1 - 0.37 10.8 6.2 0.69 9.9 3.9 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein PLAC9 PF15205.1 OAP55804.1 - 0.48 10.7 3.2 0.94 9.7 0.4 2.4 1 1 1 2 2 2 0 Placenta-specific protein 9 TMF_DNA_bd PF12329.3 OAP55804.1 - 1.6 8.5 8.1 1.8 8.4 3.7 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Acyltransferase PF01553.16 OAP55805.1 - 1.2e-10 40.9 0.0 0.00046 19.6 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase WD40 PF00400.27 OAP55806.1 - 3.9e-45 150.1 13.9 7.8e-08 31.9 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 OAP55806.1 - 3.3e-12 45.9 0.1 6.3e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP55806.1 - 1.5e-06 27.6 0.0 3.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 OAP55806.1 - 1.9e-05 23.0 3.3 0.025 12.7 0.0 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 MgtE_N PF03448.12 OAP55806.1 - 0.0079 16.5 0.1 0.022 15.0 0.1 1.7 1 0 0 1 1 1 1 MgtE intracellular N domain PRANC PF09372.5 OAP55806.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 PRANC domain FAM60A PF15396.1 OAP55806.1 - 6.5 6.4 12.4 0.44 10.2 1.7 2.6 2 0 0 2 2 2 0 Protein Family FAM60A Prenyltransf PF01255.14 OAP55807.1 - 4.2e-83 277.8 0.0 1e-82 276.6 0.0 1.6 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF605 PF04652.11 OAP55807.1 - 0.86 8.9 12.7 1.3 8.3 8.8 1.2 1 0 0 1 1 1 0 Vta1 like OTT_1508_deam PF14441.1 OAP55808.1 - 3e-12 46.5 0.1 5.4e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Peptidase_M41 PF01434.13 OAP55809.1 - 1e-63 214.6 1.3 1.6e-63 214.0 0.9 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 OAP55809.1 - 2.9e-43 147.2 0.0 1e-42 145.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAP55809.1 - 3.4e-06 26.8 0.0 1.4e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 OAP55809.1 - 8.1e-06 26.6 0.5 3.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP55809.1 - 1.1e-05 25.5 0.2 0.0048 17.0 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 OAP55809.1 - 3.9e-05 23.7 0.0 0.00013 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 OAP55809.1 - 0.00011 21.2 0.0 0.00024 20.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 OAP55809.1 - 0.00038 19.3 0.0 0.00085 18.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 OAP55809.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 OAP55809.1 - 0.0011 18.8 0.0 0.0037 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 OAP55809.1 - 0.0013 17.6 0.0 0.0031 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 OAP55809.1 - 0.0014 17.7 1.4 0.0049 15.9 0.3 2.2 1 1 1 2 2 2 1 Zeta toxin AAA_19 PF13245.1 OAP55809.1 - 0.0021 17.7 1.5 0.0088 15.7 0.2 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 OAP55809.1 - 0.003 17.5 0.0 0.0076 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAP55809.1 - 0.003 16.7 0.3 0.0087 15.2 0.2 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 OAP55809.1 - 0.0036 17.2 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAP55809.1 - 0.0065 15.8 0.4 0.12 11.7 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.1 OAP55809.1 - 0.011 15.2 0.5 8.3 5.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 OAP55809.1 - 0.013 15.1 0.1 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RCR PF12273.3 OAP55810.1 - 0.082 13.4 1.7 0.19 12.2 1.2 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4381 PF14316.1 OAP55810.1 - 0.13 12.3 0.1 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3311 PF11755.3 OAP55810.1 - 0.19 11.3 1.5 0.29 10.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) DUF1223 PF06764.6 OAP55811.1 - 3.1e-47 161.0 0.0 4.6e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) SARG PF15385.1 OAP55811.1 - 1.3 8.3 5.0 1.7 7.9 3.5 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein K_trans PF02705.11 OAP55813.1 - 7.3e-183 608.7 12.9 8.8e-183 608.4 9.0 1.1 1 0 0 1 1 1 1 K+ potassium transporter RA PF00788.18 OAP55814.1 - 1.6e-08 34.8 0.0 4.5e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FEZ PF07763.8 OAP55814.1 - 0.0086 15.8 0.2 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 FEZ-like protein TPR_10 PF13374.1 OAP55816.1 - 1.6e-114 371.0 18.8 3.5e-14 52.1 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 OAP55816.1 - 2.2e-89 293.4 33.9 2.2e-17 62.7 0.6 6.7 1 1 4 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 OAP55816.1 - 1.1e-36 121.6 21.7 0.0024 17.5 0.1 10.3 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 OAP55816.1 - 7.3e-25 87.0 9.4 6.8e-07 29.8 0.0 6.3 3 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAP55816.1 - 4.3e-20 71.1 19.9 1.3e-05 24.6 1.2 5.9 1 1 7 8 8 8 8 TPR repeat TPR_1 PF00515.23 OAP55816.1 - 6e-19 66.7 18.3 0.018 14.6 0.1 9.4 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 OAP55816.1 - 1.8e-18 65.1 12.1 0.23 11.7 0.0 9.3 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_4 PF07721.9 OAP55816.1 - 1.6e-14 52.7 0.0 4.2 8.0 0.0 8.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP55816.1 - 2.8e-12 45.5 18.9 0.74 9.8 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat NB-ARC PF00931.17 OAP55816.1 - 1.6e-11 43.6 0.0 7.1e-11 41.4 0.0 2.1 2 1 1 3 3 3 1 NB-ARC domain TPR_19 PF14559.1 OAP55816.1 - 1.5e-10 41.2 8.0 0.043 14.1 0.3 5.8 2 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAP55816.1 - 4.5e-10 39.2 14.6 13 6.7 0.0 9.8 7 1 2 9 9 9 0 Tetratricopeptide repeat PPR PF01535.15 OAP55816.1 - 3.1e-09 36.2 5.1 11 6.2 0.0 8.0 8 0 0 8 8 8 0 PPR repeat TPR_8 PF13181.1 OAP55816.1 - 1.3e-07 30.8 18.9 0.031 14.0 0.2 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 OAP55816.1 - 2.7e-07 30.7 0.8 3.2e-06 27.2 0.1 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Apc3 PF12895.2 OAP55816.1 - 4.3e-06 26.7 8.6 0.57 10.3 0.4 5.9 2 1 5 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.1 OAP55816.1 - 5.4e-05 23.0 0.8 25 4.9 0.0 5.8 7 0 0 7 7 7 0 PPR repeat family CK2S PF15011.1 OAP55816.1 - 0.00023 21.0 6.1 5.9 6.6 0.0 5.8 7 1 0 7 7 5 0 Casein Kinase 2 substrate Rab5-bind PF09311.6 OAP55816.1 - 0.00037 20.4 10.5 5.2 6.9 0.1 6.5 2 1 5 7 7 7 0 Rabaptin-like protein Death PF00531.17 OAP55816.1 - 0.0009 18.9 1.0 89 2.9 0.0 6.5 7 0 0 7 7 7 0 Death domain Abhydrolase_5 PF12695.2 OAP55816.1 - 0.002 17.8 0.0 0.022 14.4 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2277 PF10041.4 OAP55816.1 - 0.0027 17.6 0.1 9.6 6.2 0.0 4.3 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2277) DUF676 PF05057.9 OAP55816.1 - 0.0029 16.9 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PPR_3 PF13812.1 OAP55816.1 - 0.0084 16.3 8.7 30 5.2 0.0 6.9 7 0 0 7 7 7 0 Pentatricopeptide repeat domain PGAP1 PF07819.8 OAP55816.1 - 0.013 15.1 0.0 0.047 13.2 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Cutinase PF01083.17 OAP55816.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase AAA_22 PF13401.1 OAP55816.1 - 0.029 14.5 0.0 0.25 11.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain BTAD PF03704.12 OAP55816.1 - 0.11 12.7 19.5 10 6.4 0.2 7.2 1 1 6 7 7 7 0 Bacterial transcriptional activator domain FUR PF01475.14 OAP55816.1 - 0.24 11.3 6.7 55 3.7 0.0 5.4 7 0 0 7 7 6 0 Ferric uptake regulator family Na_H_Exchanger PF00999.16 OAP55818.1 - 2.7e-35 121.6 28.1 3.5e-35 121.2 19.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TauD PF02668.11 OAP55819.1 - 7.8e-50 169.9 0.6 9e-50 169.7 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 OAP55819.1 - 0.0024 18.3 0.3 2.8 8.5 0.0 2.5 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily RNA_GG_bind PF10258.4 OAP55819.1 - 0.1 12.2 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 PHAX RNA-binding domain Sod_Cu PF00080.15 OAP55820.1 - 0.079 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) adh_short PF00106.20 OAP55820.1 - 0.14 12.0 2.2 0.29 11.0 0.2 2.5 2 1 0 2 2 2 0 short chain dehydrogenase FGGY_C PF02782.11 OAP55821.1 - 6e-71 238.1 0.3 9.1e-71 237.5 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 OAP55821.1 - 1e-65 221.5 0.0 1.3e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF3429 PF11911.3 OAP55822.1 - 3.8e-38 130.6 11.4 5.2e-38 130.2 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) COX6A PF02046.10 OAP55823.1 - 6.9e-47 158.1 0.4 7.9e-47 157.9 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Apc5 PF12862.2 OAP55824.1 - 8.6e-35 118.4 3.8 8.6e-35 118.4 2.6 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_4 PF07721.9 OAP55824.1 - 0.0051 17.1 14.1 2.3 8.9 0.4 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP55824.1 - 0.019 15.5 11.3 15 6.5 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAP55824.1 - 0.031 14.5 8.5 1.2 9.4 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 OAP55824.1 - 0.039 13.8 7.6 2.6 7.9 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP55824.1 - 0.049 13.4 3.8 26 4.9 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP55824.1 - 0.98 9.4 19.1 2.9 7.8 1.8 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SAICAR_synt PF01259.13 OAP55825.1 - 4.8e-90 300.9 0.1 6e-90 300.7 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase CIA30 PF08547.7 OAP55826.1 - 2e-38 131.7 0.0 2.7e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.17 OAP55827.1 - 2e-26 91.4 0.1 5.7e-13 48.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP55827.1 - 4.8e-17 61.7 0.1 2.4e-07 30.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP55827.1 - 2.3e-07 30.5 0.2 0.023 14.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 OAP55828.1 - 5.3e-120 392.0 0.0 1.1e-22 80.1 0.0 4.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 OAP55828.1 - 1.9e-73 238.8 0.0 1.3e-07 31.0 0.0 9.8 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 OAP55828.1 - 2.1e-52 173.9 2.4 3.3e-08 33.5 0.0 8.1 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP55828.1 - 7.2e-51 165.0 0.0 0.00023 21.1 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 OAP55828.1 - 1.3e-49 165.7 0.0 4e-08 33.5 0.0 6.8 3 2 5 8 8 8 7 Ankyrin repeats (many copies) NACHT PF05729.7 OAP55828.1 - 7.7e-09 35.4 0.7 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 OAP55828.1 - 0.0001 22.4 0.1 0.00051 20.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2383 PF09537.5 OAP55828.1 - 0.087 13.0 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Syntaxin_2 PF14523.1 OAP55828.1 - 0.17 11.8 2.4 1.2 9.2 0.0 3.2 4 0 0 4 4 4 0 Syntaxin-like protein Ank_2 PF12796.2 OAP55829.1 - 1.4e-12 47.7 1.1 5.4e-07 29.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP55829.1 - 2.9e-10 40.3 1.4 7.6e-07 29.4 0.1 4.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 OAP55829.1 - 6.7e-10 38.2 4.2 7.2e-08 31.8 0.4 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAP55829.1 - 5.7e-08 32.2 3.1 0.0049 16.9 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAP55829.1 - 5.3e-06 26.4 3.7 0.00023 21.3 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.8 OAP55829.1 - 6.3e-05 22.5 0.2 0.00037 20.0 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain TMF_TATA_bd PF12325.3 OAP55829.1 - 0.00016 21.4 3.5 0.00016 21.4 2.4 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.14 OAP55829.1 - 0.00076 17.3 4.4 0.0012 16.6 3.0 1.2 1 0 0 1 1 1 1 Myosin tail APG6 PF04111.7 OAP55829.1 - 6.7 5.6 8.7 12 4.8 5.9 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 ADH_zinc_N_2 PF13602.1 OAP55831.1 - 9e-18 65.3 0.0 1.9e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAP55831.1 - 4.4e-16 58.6 0.0 8.1e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribonuclease_3 PF00636.21 OAP55833.1 - 1.5e-38 131.7 0.0 9.3e-22 77.6 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAP55833.1 - 3.6e-26 91.6 0.0 1.7e-15 57.0 0.0 3.8 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 OAP55833.1 - 2.2e-23 81.8 0.1 5.8e-23 80.4 0.0 1.7 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.24 OAP55833.1 - 1.6e-18 66.8 0.0 3.2e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP55833.1 - 1e-13 50.9 0.0 2.8e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP55833.1 - 1e-08 35.2 0.0 8.6e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 OAP55833.1 - 0.00056 20.4 0.0 0.41 11.2 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Piwi PF02171.12 OAP55834.1 - 4.1e-71 239.4 0.0 8.7e-71 238.3 0.0 1.5 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 OAP55834.1 - 1e-12 47.2 0.3 4.9e-12 45.0 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1785) PAZ PF02170.17 OAP55834.1 - 1.2e-12 47.2 0.0 3.4e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 PAZ domain Hydrophobin PF01185.13 OAP55835.1 - 2.5e-10 40.6 11.9 4.2e-10 39.9 8.2 1.4 1 0 0 1 1 1 1 Fungal hydrophobin WD40 PF00400.27 OAP55836.1 - 6e-88 285.8 34.2 9.1e-14 50.7 0.3 8.1 7 1 1 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 OAP55836.1 - 1.4e-11 43.2 16.4 0.018 13.1 0.2 6.1 1 1 5 6 6 6 6 Nucleoporin Nup120/160 NACHT PF05729.7 OAP55836.1 - 6.5e-10 38.9 0.0 1.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP55836.1 - 7.1e-07 29.3 2.9 7.7e-07 29.2 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain Robl_LC7 PF03259.12 OAP55836.1 - 1.8e-05 24.1 3.2 3.5 7.2 0.0 6.2 3 2 4 7 7 7 2 Roadblock/LC7 domain IKI3 PF04762.7 OAP55836.1 - 5.3e-05 21.2 0.2 1.4 6.5 0.0 3.9 1 1 2 4 4 4 3 IKI3 family AAA_22 PF13401.1 OAP55836.1 - 0.0043 17.1 0.0 0.018 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 OAP55836.1 - 0.045 13.9 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 OAP55836.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CbiA PF01656.18 OAP55836.1 - 0.055 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 OAP55836.1 - 0.055 13.0 0.7 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 OAP55836.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PD40 PF07676.7 OAP55836.1 - 2 8.1 21.8 48 3.7 0.0 7.6 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.8 OAP55837.1 - 4.9e-32 111.2 0.0 6.6e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP55837.1 - 6e-07 28.5 0.0 1.2e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAP55837.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP55837.1 - 0.034 13.6 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.15 OAP55837.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 OAP55837.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.3 OAP55837.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) adh_short_C2 PF13561.1 OAP55838.1 - 2.7e-28 99.3 0.0 3.4e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP55838.1 - 1.4e-25 90.1 0.0 5.8e-25 88.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP55838.1 - 1.3e-09 37.9 0.0 8.1e-09 35.3 0.0 1.9 1 1 1 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP55838.1 - 0.048 13.4 0.2 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 OAP55838.1 - 0.088 11.8 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ING PF12998.2 OAP55839.1 - 2.5e-09 37.3 0.8 1.1e-08 35.3 0.5 2.1 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 OAP55839.1 - 3.8e-09 36.0 8.7 6.3e-09 35.3 6.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAP55839.1 - 0.089 12.1 3.6 0.16 11.2 2.5 1.4 1 0 0 1 1 1 0 PHD-finger Drf_GBD PF06371.8 OAP55840.1 - 1.8e-13 50.2 0.6 5e-11 42.3 0.4 2.3 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Sugar_tr PF00083.19 OAP55842.1 - 3.9e-35 121.2 25.7 1.1e-34 119.8 17.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55842.1 - 3e-30 105.1 32.8 3.7e-24 85.1 13.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.22 OAP55845.1 - 1.7e-62 207.1 2.4 4.6e-22 77.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SWIRM PF04433.12 OAP55846.1 - 2.9e-34 117.0 0.1 6.5e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 OAP55846.1 - 3.7e-09 36.5 0.1 6.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAP55846.1 - 8.9e-08 32.1 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain BTB PF00651.26 OAP55847.1 - 6.1e-06 26.1 0.0 2.2e-05 24.4 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain AAA PF00004.24 OAP55848.1 - 2.6e-12 47.0 0.0 6.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP55848.1 - 6.2e-07 29.6 0.1 3e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP55848.1 - 1.7e-05 24.9 0.1 0.00094 19.2 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 OAP55848.1 - 1.7e-05 24.5 0.0 4.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAP55848.1 - 4.9e-05 22.9 0.8 0.00017 21.2 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 OAP55848.1 - 6e-05 22.2 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 OAP55848.1 - 0.0002 20.1 0.2 0.00052 18.8 0.1 1.6 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 OAP55848.1 - 0.00022 21.0 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP55848.1 - 0.00054 20.7 0.2 0.002 18.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 OAP55848.1 - 0.00058 19.0 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 OAP55848.1 - 0.00063 19.6 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP55848.1 - 0.018 15.3 0.0 0.078 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 OAP55848.1 - 0.026 13.9 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 OAP55848.1 - 0.052 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 OAP55848.1 - 0.098 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 OAP55848.1 - 0.13 11.0 0.0 0.35 9.6 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain ABC_membrane_2 PF06472.10 OAP55849.1 - 4.3e-109 363.9 2.9 4.3e-109 363.9 2.0 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 OAP55849.1 - 1.5e-18 67.4 0.0 4.2e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAP55849.1 - 8.1e-05 22.7 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 OAP55849.1 - 0.0055 17.0 0.3 0.0055 17.0 0.2 2.6 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 OAP55849.1 - 0.013 14.7 0.6 0.12 11.5 0.0 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAP55849.1 - 0.013 15.4 0.1 0.075 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 OAP55849.1 - 0.014 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2587 PF10759.4 OAP55849.1 - 0.016 14.6 0.4 0.038 13.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF258 PF03193.11 OAP55849.1 - 0.069 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 OAP55849.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Hemerythrin PF01814.18 OAP55851.1 - 2.1e-08 34.4 0.4 3.6e-08 33.6 0.3 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HAD_2 PF13419.1 OAP55852.1 - 3.7e-26 92.4 0.1 4.5e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP55852.1 - 5.4e-05 22.8 0.0 9.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 OAP55852.1 - 0.00013 22.4 0.0 0.0008 19.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SR-25 PF10500.4 OAP55854.1 - 0.42 10.0 6.4 0.75 9.2 4.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chitin_synth_2 PF03142.10 OAP55855.1 - 1e-231 769.9 0.0 1.3e-231 769.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 OAP55855.1 - 1.5e-59 201.7 0.0 3.2e-59 200.6 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 OAP55855.1 - 1.4e-16 59.9 0.6 1.1e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 OAP55855.1 - 1.4e-15 57.7 0.0 1.1e-12 48.2 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAP55855.1 - 2.6e-15 56.6 2.4 2.6e-15 56.6 1.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 OAP55855.1 - 1.1e-13 50.7 0.2 7.5e-13 48.0 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 OAP55855.1 - 2.6e-06 26.8 0.0 6.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAP55855.1 - 0.0068 16.1 0.0 0.34 10.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Jiv90 PF14901.1 OAP55855.1 - 0.098 12.6 0.2 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Chitin_synth_2 PF03142.10 OAP55856.1 - 7.6e-255 846.2 0.8 1e-254 845.9 0.5 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 OAP55856.1 - 3.7e-164 547.5 0.0 4.6e-164 547.1 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 OAP55856.1 - 7e-20 70.6 0.0 5.3e-14 51.7 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 OAP55856.1 - 1.1e-15 57.1 2.1 3.5e-15 55.5 1.4 1.9 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 OAP55856.1 - 1.1e-15 57.8 5.0 3.3e-15 56.2 3.5 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAP55856.1 - 3.7e-15 56.3 0.2 2.9e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 OAP55856.1 - 9e-06 25.4 0.0 0.0016 18.1 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 OAP55856.1 - 0.0023 17.2 0.2 0.035 13.4 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 21 AAA_22 PF13401.1 OAP55856.1 - 0.0042 17.2 0.0 0.021 14.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAP55856.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 PLDc_2 PF13091.1 OAP55857.1 - 2.7e-15 56.2 0.0 1.9e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 OAP55857.1 - 0.00092 18.9 0.5 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 OAP55857.1 - 0.0041 16.1 0.0 0.32 9.9 0.0 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB PSDC PF12588.3 OAP55858.1 - 4.5e-41 139.7 0.0 8e-41 138.9 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 OAP55858.1 - 1.8e-37 128.6 0.0 2.6e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 OAP55858.1 - 0.0005 19.7 0.1 0.48 10.1 0.0 2.4 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.15 OAP55858.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.17 OAP55858.1 - 0.037 14.0 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M23 TPP_enzyme_N PF02776.13 OAP55859.1 - 1.3e-37 128.9 0.0 3.1e-35 121.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAP55859.1 - 2.7e-20 72.5 0.0 5e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP55859.1 - 7.4e-19 67.8 0.0 3.6e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain HET PF06985.6 OAP55860.1 - 1.9e-08 34.5 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1518 PF07469.7 OAP55860.1 - 0.0093 16.0 0.4 0.017 15.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1518) CHAT PF12770.2 OAP55861.1 - 7.8e-25 87.5 0.4 4.1e-24 85.2 0.0 2.0 2 0 0 2 2 2 1 CHAT domain TPR_2 PF07719.12 OAP55861.1 - 0.034 14.0 0.7 0.29 11.1 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 OAP55862.1 - 4.8e-15 55.1 0.1 8.3e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Trs65 PF12735.2 OAP55863.1 - 0.081 12.2 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 HSP70 PF00012.15 OAP55864.1 - 2.6e-05 22.3 0.2 6.1e-05 21.1 0.0 1.7 2 1 0 2 2 2 1 Hsp70 protein FTZ PF03867.9 OAP55866.1 - 0.041 13.1 4.9 0.07 12.3 3.4 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Sugar_tr PF00083.19 OAP55867.1 - 1.3e-117 393.1 24.7 1.5e-117 392.9 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55867.1 - 4.4e-24 84.8 49.4 9.5e-20 70.5 17.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP55867.1 - 7.1e-07 27.9 25.9 0.0019 16.6 7.0 3.3 3 1 0 3 3 3 3 MFS/sugar transport protein DUF3154 PF11351.3 OAP55867.1 - 0.09 12.5 0.0 0.29 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) 7TM-7TMR_HD PF07698.6 OAP55867.1 - 0.39 10.1 17.6 0.054 12.9 1.6 3.5 3 1 0 3 3 3 0 7TM receptor with intracellular HD hydrolase MCM PF00493.18 OAP55868.1 - 3.2e-131 437.0 0.3 5.1e-131 436.3 0.2 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAP55868.1 - 1.2e-15 58.0 0.0 3.3e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAP55868.1 - 9.4e-07 28.2 0.0 1.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAP55868.1 - 0.0044 16.6 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_pol_3_Rpc31 PF11705.3 OAP55869.1 - 0.018 14.9 3.7 0.018 14.9 2.6 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3206 PF11472.3 OAP55870.1 - 0.013 15.2 0.6 0.17 11.6 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3206) Transket_pyr PF02779.19 OAP55871.1 - 3.6e-65 218.7 0.0 6.1e-65 218.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 OAP55871.1 - 4.9e-56 189.6 0.0 6.6e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_17 PF00332.13 OAP55871.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Nramp PF01566.13 OAP55873.1 - 3.7e-92 308.8 23.2 3.7e-92 308.8 16.1 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Thiolase_N PF00108.18 OAP55875.1 - 1e-81 273.7 1.2 1.7e-81 273.0 0.9 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAP55875.1 - 7.8e-42 141.5 0.0 1.4e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain LMWSLP_N PF12211.3 OAP55875.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal ketoacyl-synt PF00109.21 OAP55875.1 - 0.024 14.1 5.3 0.23 10.8 0.7 3.4 2 2 2 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain Aldo_ket_red PF00248.16 OAP55877.1 - 7.6e-71 238.2 0.1 9.1e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_psq PF05225.11 OAP55877.1 - 0.17 11.4 0.6 46 3.6 0.0 3.2 3 0 0 3 3 3 0 helix-turn-helix, Psq domain DUF1664 PF07889.7 OAP55877.1 - 0.2 11.4 1.2 1.5 8.6 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) RHH_1 PF01402.16 OAP55877.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.7 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family Nodulin_late PF07127.6 OAP55878.1 - 0.018 15.1 12.1 0.87 9.7 0.2 3.2 3 0 0 3 3 3 0 Late nodulin protein Squash PF00299.13 OAP55878.1 - 0.99 9.2 28.1 1.7 8.5 2.5 3.4 3 0 0 3 3 3 0 Squash family serine protease inhibitor DIOX_N PF14226.1 OAP55879.1 - 1.5e-22 80.3 0.0 2.8e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP55879.1 - 8.2e-22 77.3 0.0 1.9e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pyr_redox_3 PF13738.1 OAP55879.1 - 9.7e-13 48.6 0.0 2.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP55879.1 - 0.00012 22.0 0.1 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Nairo_nucleo PF02477.10 OAP55879.1 - 0.026 13.2 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Nucleocapsid N protein NAD_binding_9 PF13454.1 OAP55879.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding bZIP_2 PF07716.10 OAP55880.1 - 2.5e-11 43.2 17.0 3.9e-11 42.6 11.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 OAP55880.1 - 7.7e-06 25.7 16.9 1.4e-05 24.9 11.7 1.5 1 1 0 1 1 1 1 bZIP transcription factor DUF3552 PF12072.3 OAP55880.1 - 0.0024 17.1 8.6 0.0031 16.7 6.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) IncA PF04156.9 OAP55880.1 - 0.0027 17.3 3.3 0.0036 16.9 2.3 1.2 1 0 0 1 1 1 1 IncA protein Herpes_BLRF2 PF05812.7 OAP55880.1 - 0.0033 17.2 1.0 0.0033 17.2 0.7 1.9 1 1 0 2 2 2 1 Herpesvirus BLRF2 protein V_ATPase_I PF01496.14 OAP55880.1 - 0.016 13.0 1.2 0.02 12.8 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_T4_Ndd PF06591.6 OAP55880.1 - 0.023 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) TSC22 PF01166.13 OAP55880.1 - 0.053 13.4 1.4 0.1 12.5 0.7 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF4094 PF13334.1 OAP55880.1 - 0.093 13.1 1.9 0.15 12.4 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF904 PF06005.7 OAP55880.1 - 0.11 12.7 6.0 0.15 12.4 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Phlebovirus_NSM PF07246.6 OAP55880.1 - 0.12 11.4 4.8 0.15 11.1 3.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CMS1 PF14617.1 OAP55880.1 - 0.23 10.5 6.2 0.31 10.0 4.3 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DivIC PF04977.10 OAP55880.1 - 0.32 10.5 5.1 0.54 9.7 3.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Rabaptin PF03528.10 OAP55880.1 - 0.33 10.8 6.2 0.48 10.3 4.3 1.2 1 0 0 1 1 1 0 Rabaptin DUF972 PF06156.8 OAP55880.1 - 0.33 11.2 4.3 0.42 10.9 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) GBP_C PF02841.9 OAP55880.1 - 1.1 8.3 9.3 1.5 7.9 6.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain XhlA PF10779.4 OAP55880.1 - 8.4 6.3 7.7 16 5.5 5.4 1.5 1 1 0 1 1 1 0 Haemolysin XhlA Sulfatase PF00884.18 OAP55881.1 - 5.2e-65 219.6 0.2 7.7e-65 219.0 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 OAP55881.1 - 0.0006 19.2 1.2 0.0046 16.3 0.9 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 OAP55882.1 - 7.9e-44 149.8 29.0 7.9e-44 149.8 20.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP55882.1 - 1.1e-12 47.3 9.6 1.1e-12 47.3 6.6 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 OAP55882.1 - 1.8e-05 23.0 7.8 1.8e-05 23.0 5.4 1.9 2 1 1 3 3 3 1 Transmembrane secretion effector MFS_1 PF07690.11 OAP55883.1 - 3.1e-24 85.3 18.3 3.9e-24 85.0 12.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAP55883.1 - 0.045 13.2 5.1 0.014 14.9 1.3 1.8 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 TauD PF02668.11 OAP55884.1 - 6.9e-43 147.1 0.0 8.3e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.6 OAP55884.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) GFA PF04828.9 OAP55885.1 - 3.3e-19 68.6 0.7 9.5e-12 44.7 0.1 3.5 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.14 OAP55885.1 - 0.064 13.0 1.7 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S27a zf-ribbon_3 PF13248.1 OAP55885.1 - 2.8 7.2 10.2 5 6.4 0.0 3.5 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 OAP55885.1 - 3 7.4 9.4 7.7 6.1 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain DUF3279 PF11682.3 OAP55885.1 - 6.3 6.3 8.2 1.7 8.2 0.0 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3279) NOB1_Zn_bind PF08772.6 OAP55885.1 - 7.9 6.3 11.2 1.3 8.8 0.0 3.5 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like Sod_Fe_C PF02777.13 OAP55886.1 - 1.4e-39 134.1 0.4 2.4e-39 133.4 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAP55886.1 - 3.7e-29 100.7 1.5 6.5e-29 100.0 1.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.7 OAP55887.1 - 1.4e-29 103.3 4.0 1.4e-29 103.3 2.8 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 OAP55887.1 - 1.9e-15 56.3 2.6 4.3e-15 55.2 1.8 1.7 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 OAP55887.1 - 0.019 15.0 4.6 0.084 12.9 3.2 2.1 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 OAP55887.1 - 0.032 14.0 6.1 0.055 13.3 0.4 2.7 2 0 0 2 2 2 0 DExH-box splicing factor binding site adh_short PF00106.20 OAP55888.1 - 6e-31 107.6 1.1 8e-31 107.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55888.1 - 3.2e-26 92.5 0.1 4e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55888.1 - 4.3e-16 59.0 0.5 6.3e-16 58.5 0.4 1.1 1 0 0 1 1 1 1 KR domain DUF1372 PF07116.6 OAP55888.1 - 0.011 15.6 0.1 0.028 14.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) DUF3237 PF11578.3 OAP55888.1 - 0.03 13.6 0.2 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) Peripla_BP_6 PF13458.1 OAP55888.1 - 0.032 13.5 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein NAD_binding_10 PF13460.1 OAP55888.1 - 0.036 14.0 1.2 0.047 13.6 0.9 1.4 1 1 0 1 1 1 0 NADH(P)-binding DFP PF04127.10 OAP55888.1 - 0.046 13.3 0.6 0.098 12.2 0.4 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CABS1 PF15367.1 OAP55888.1 - 0.056 12.3 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 3HCDH_N PF02737.13 OAP55888.1 - 0.12 12.0 1.2 0.29 10.7 0.8 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 OAP55888.1 - 0.17 10.9 1.4 0.24 10.4 0.2 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1741 PF08427.5 OAP55889.1 - 7.9e-68 228.4 0.0 7.1e-66 222.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.15 OAP55890.1 - 1.2e-20 73.5 0.0 1.6e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Dabb PF07876.7 OAP55891.1 - 1.4e-25 89.5 0.1 1.7e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain cobW PF02492.14 OAP55892.1 - 5.5e-35 120.4 0.0 6.7e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 OAP55892.1 - 4.3e-06 25.7 0.2 0.0055 15.5 0.0 2.1 2 0 0 2 2 2 2 ArgK protein PRK PF00485.13 OAP55892.1 - 0.0078 15.7 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 OAP55892.1 - 0.019 15.7 0.1 0.038 14.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 OAP55892.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.18 OAP55892.1 - 0.045 13.1 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.9 OAP55892.1 - 0.09 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 OAP55892.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain BING4CT PF08149.6 OAP55893.1 - 2.7e-40 135.7 0.1 1e-36 124.2 0.0 2.9 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 OAP55893.1 - 1.7e-05 24.5 0.0 0.01 15.6 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat COesterase PF00135.23 OAP55894.1 - 5.7e-102 342.1 0.4 6.7e-102 341.9 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP55894.1 - 0.003 17.1 0.1 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 OAP55894.1 - 0.061 12.7 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ank_2 PF12796.2 OAP55895.1 - 1.2e-18 67.2 2.3 4.8e-07 30.0 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 OAP55895.1 - 5.3e-12 44.9 3.5 0.0038 16.9 0.0 6.4 6 1 1 7 7 7 2 Ankyrin repeat Ank_3 PF13606.1 OAP55895.1 - 2.3e-09 36.5 0.1 0.0069 16.5 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 OAP55895.1 - 1e-08 35.4 2.7 0.0034 17.8 0.0 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP55895.1 - 3.9e-07 30.1 5.6 0.076 13.2 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) SnoaL PF07366.7 OAP55896.1 - 0.00033 20.2 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase GFO_IDH_MocA PF01408.17 OAP55898.1 - 3e-22 79.3 0.2 5.4e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP55898.1 - 1.2e-07 31.5 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans_2 PF11951.3 OAP55899.1 - 3.1e-09 35.9 0.0 7.3e-08 31.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP55899.1 - 0.023 14.6 3.9 0.047 13.6 2.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 OAP55900.1 - 1.4e-58 198.5 0.0 2e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 OAP55901.1 - 2.9e-99 332.6 33.2 3.4e-99 332.4 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP55901.1 - 1.2e-30 106.4 30.7 1.2e-30 106.4 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP55901.1 - 0.074 12.8 0.0 0.074 12.8 0.0 2.9 3 0 0 3 3 3 0 MFS_1 like family SDH_alpha PF03313.10 OAP55901.1 - 1.4 7.9 7.3 1.1 8.2 0.1 2.6 2 1 1 3 3 3 0 Serine dehydratase alpha chain Tox-MPTase3 PF15639.1 OAP55902.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 3 Acetyltransf_1 PF00583.19 OAP55903.1 - 4e-08 33.1 0.0 6.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP55903.1 - 7.8e-07 29.1 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP55903.1 - 0.00065 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP55903.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Palm_thioest PF02089.10 OAP55904.1 - 5.6e-50 169.8 0.0 7.7e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 OAP55904.1 - 4.4e-05 23.4 0.0 7.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 OAP55904.1 - 0.002 17.2 0.0 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 OAP55904.1 - 0.026 13.8 0.0 0.12 11.6 0.0 2.0 1 1 0 1 1 1 0 Lipase (class 2) Glyco_hydro_16 PF00722.16 OAP55906.1 - 1.5e-14 53.7 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Neuromodulin_N PF10580.4 OAP55906.1 - 0.19 11.3 1.9 0.32 10.6 0.4 2.0 2 0 0 2 2 2 0 Gap junction protein N-terminal region Methyltransf_16 PF10294.4 OAP55907.1 - 4.9e-21 74.9 0.0 5.9e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAP55907.1 - 1.4e-05 25.6 0.0 3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAP55907.1 - 0.00092 18.4 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 OAP55907.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 OAP55907.1 - 0.039 12.9 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.1 OAP55907.1 - 0.041 13.4 0.1 0.29 10.6 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 OAP55907.1 - 0.045 12.8 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.15 OAP55907.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 OAP55907.1 - 0.13 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF1880 PF08976.6 OAP55908.1 - 10 6.3 8.2 1.9 8.6 2.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1880) KTI12 PF08433.5 OAP55909.1 - 6.6e-62 209.1 0.0 1.5e-61 207.9 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAP55909.1 - 1.6e-08 34.5 0.1 3.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP55909.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP55909.1 - 0.0053 17.5 0.0 0.011 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain zf-C2H2_4 PF13894.1 OAP55910.1 - 7.2 7.1 14.1 2.1 8.8 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Ion_trans_2 PF07885.11 OAP55913.1 - 5.1e-28 96.6 17.9 2.9e-17 62.1 2.7 3.4 6 0 0 6 6 6 2 Ion channel DUF3669 PF12417.3 OAP55914.1 - 3.3e-07 29.9 0.0 6.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein Stc1 PF12898.2 OAP55915.1 - 9.7e-16 57.6 12.0 3e-15 56.0 8.3 1.9 1 0 0 1 1 1 1 Stc1 domain RCC_reductase PF06405.6 OAP55915.1 - 0.17 10.8 0.4 0.35 9.7 0.0 1.7 2 0 0 2 2 2 0 Red chlorophyll catabolite reductase (RCC reductase) Pkinase PF00069.20 OAP55916.1 - 9.5e-60 201.9 0.0 1.5e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP55916.1 - 2.5e-31 108.6 0.0 5.9e-29 100.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 OAP55916.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GTP_cyclohydro2 PF00925.15 OAP55918.1 - 7.2e-57 191.3 0.0 7.1e-52 175.0 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Polyoma_agno PF01736.11 OAP55919.1 - 0.19 11.4 0.7 2.8 7.6 0.0 2.2 1 1 1 2 2 2 0 Polyomavirus agnoprotein DUF1325 PF07039.6 OAP55920.1 - 1.3e-18 66.8 0.8 2.2e-18 66.1 0.5 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain zf-C4H2 PF10146.4 OAP55920.1 - 0.0056 16.7 0.6 0.011 15.7 0.2 1.6 2 0 0 2 2 2 1 Zinc finger-containing protein PMI_typeI PF01238.16 OAP55921.1 - 2.4e-136 454.5 0.0 2.8e-136 454.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 OAP55921.1 - 0.071 12.6 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Cupin domain p450 PF00067.17 OAP55922.1 - 2.3e-37 128.6 0.0 1.2e-25 89.9 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 GFO_IDH_MocA PF01408.17 OAP55923.1 - 1.2e-21 77.4 0.0 2e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 OAP55923.1 - 0.0011 19.3 0.2 0.0018 18.6 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 OAP55923.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Cytochrom_C PF00034.16 OAP55924.1 - 2.8e-09 37.6 0.1 8.2e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.1 OAP55924.1 - 4.6e-08 33.0 0.8 4.3e-07 29.9 0.6 2.2 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 OAP55924.1 - 0.0009 18.7 0.3 0.0043 16.5 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.1 OAP55924.1 - 0.018 14.7 0.6 0.055 13.1 0.3 1.8 2 0 0 2 2 2 0 Haem-binding domain Cytochrome-c551 PF10643.4 OAP55924.1 - 0.049 12.9 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Cytochrom_C1 PF02167.10 OAP55924.1 - 0.072 12.7 0.2 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 Cytochrome C1 family CRM1_C PF08767.6 OAP55925.1 - 0.021 13.7 1.0 3.3 6.5 0.0 2.2 2 0 0 2 2 2 0 CRM1 C terminal RNase_PH PF01138.16 OAP55926.1 - 2.6e-14 53.6 0.0 6e-14 52.4 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAP55926.1 - 0.012 15.5 0.1 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF1180 PF06679.7 OAP55927.1 - 2.7 7.8 10.6 0.04 13.8 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Spermine_synth PF01564.12 OAP55928.1 - 6.6e-95 316.7 0.0 9.2e-95 316.2 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 OAP55928.1 - 0.015 15.8 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.11 OAP55928.1 - 0.028 13.4 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 OAP55928.1 - 0.046 14.2 0.4 0.22 12.0 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_2 PF00891.13 OAP55928.1 - 0.06 12.5 0.3 0.49 9.5 0.1 2.1 1 1 1 2 2 2 0 O-methyltransferase TRI12 PF06609.8 OAP55929.1 - 2.1e-37 128.6 22.2 2.7e-37 128.2 15.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP55929.1 - 7.2e-24 84.1 50.1 1.7e-23 82.9 33.6 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP55929.1 - 3.8e-09 35.6 14.3 3.8e-09 35.6 9.9 3.5 2 2 2 4 4 4 1 Sugar (and other) transporter p450 PF00067.17 OAP55930.1 - 2.7e-66 224.0 0.0 3.1e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Molybdopterin PF00384.17 OAP55930.1 - 0.04 12.6 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase CHAT PF12770.2 OAP55931.1 - 3.8e-37 127.9 0.1 7.7e-37 126.9 0.1 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 OAP55931.1 - 5e-12 45.5 15.8 0.018 14.9 0.1 9.0 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAP55931.1 - 2.4e-06 27.0 12.5 0.23 11.1 0.0 6.4 5 1 3 8 8 8 3 TPR repeat TPR_2 PF07719.12 OAP55931.1 - 0.00031 20.4 8.3 2.4 8.2 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAP55931.1 - 0.087 12.6 7.7 4.3 7.3 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP55931.1 - 0.1 12.2 5.5 1.9 8.2 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAP55931.1 - 0.48 10.3 8.2 70 3.5 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 OAP55932.1 - 3.5e-21 76.0 0.0 6.7e-21 75.1 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.13 OAP55932.1 - 0.014 14.7 0.1 0.23 10.7 0.1 2.1 1 1 0 1 1 1 0 Peptidase C13 family Mus7 PF09462.5 OAP55934.1 - 1.1e-23 83.9 1.6 1e-16 60.9 0.6 2.2 2 0 0 2 2 2 2 Mus7/MMS22 family PAPA-1 PF04795.7 OAP55936.1 - 1.2e-14 54.8 2.6 1.2e-14 54.8 1.8 3.5 3 0 0 3 3 3 1 PAPA-1-like conserved region Daxx PF03344.10 OAP55936.1 - 1.2 7.5 49.7 0.58 8.5 17.8 2.2 2 0 0 2 2 2 0 Daxx Family Pex14_N PF04695.8 OAP55937.1 - 1.7e-20 73.4 0.8 1.7e-20 73.4 0.5 3.3 3 2 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF937 PF06078.6 OAP55937.1 - 0.036 14.2 1.5 0.34 11.1 0.7 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Nefa_Nip30_N PF10187.4 OAP55937.1 - 0.16 12.1 2.6 1.6 8.9 0.1 2.8 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Ank_2 PF12796.2 OAP55938.1 - 5.8e-31 106.6 1.0 2e-20 72.8 0.3 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP55938.1 - 7.3e-26 90.0 1.1 1.1e-14 54.4 0.0 6.2 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 OAP55938.1 - 1.1e-24 84.9 9.4 2.5e-07 30.1 0.0 7.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 OAP55938.1 - 1.6e-23 82.1 0.1 8.9e-08 32.1 0.0 5.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP55938.1 - 3e-23 79.5 1.7 0.00012 21.9 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat adh_short PF00106.20 OAP55938.1 - 5.6e-23 81.6 7.5 8.8e-23 81.0 5.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55938.1 - 5.2e-18 65.6 0.3 8e-18 65.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55938.1 - 7.9e-11 41.9 4.7 1.3e-10 41.1 3.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP55938.1 - 3.3e-06 26.6 0.3 5.9e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.16 OAP55938.1 - 0.0022 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase WGG PF10273.4 OAP55939.1 - 1.7e-24 85.6 0.5 3.1e-24 84.8 0.3 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Cupin_2 PF07883.6 OAP55940.1 - 5.9e-16 57.7 0.0 1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 OAP55940.1 - 5.8e-06 26.0 0.0 8.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 OAP55940.1 - 5.9e-05 22.5 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 OAP55940.1 - 0.00034 20.5 0.7 0.00052 20.0 0.0 1.6 2 0 0 2 2 2 1 ARD/ARD' family Cupin_3 PF05899.7 OAP55940.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) GPI PF06560.6 OAP55940.1 - 0.0077 15.2 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.17 OAP55940.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_6 PF12852.2 OAP55940.1 - 0.044 13.3 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Cupin EutQ PF06249.7 OAP55940.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ FMO-like PF00743.14 OAP55941.1 - 2e-20 72.5 0.1 3.7e-18 65.0 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAP55941.1 - 6e-19 68.9 0.0 2.3e-18 67.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP55941.1 - 2.9e-10 39.6 0.0 3.8e-06 26.0 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP55941.1 - 2.1e-07 30.8 0.0 5.2e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP55941.1 - 4.8e-06 26.5 0.0 1.3e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP55941.1 - 0.0043 16.8 0.0 0.042 13.6 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 OAP55941.1 - 0.031 14.3 0.0 6 6.9 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Calcipressin PF04847.7 OAP55942.1 - 6.7e-37 126.8 0.2 1.2e-36 126.0 0.1 1.5 1 1 0 1 1 1 1 Calcipressin Mito_carr PF00153.22 OAP55943.1 - 5.4e-55 183.1 2.3 6.3e-20 70.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.15 OAP55944.1 - 4.1e-48 163.7 0.1 8.1e-26 90.7 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 OAP55944.1 - 3.2e-25 88.1 0.0 6.6e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.14 OAP55945.1 - 1.1e-41 142.0 5.3 4.7e-41 140.0 3.7 1.8 1 1 0 1 1 1 1 GrpE Peptidase_S49 PF01343.13 OAP55945.1 - 0.019 14.7 0.6 0.034 13.9 0.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 IncA PF04156.9 OAP55945.1 - 0.38 10.3 4.4 0.57 9.7 3.0 1.3 1 0 0 1 1 1 0 IncA protein Pam16 PF03656.8 OAP55945.1 - 0.51 10.1 3.2 0.45 10.3 0.3 2.3 2 1 0 2 2 2 0 Pam16 Bap31 PF05529.7 OAP55945.1 - 0.94 8.9 3.0 1.6 8.1 2.1 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Vps5 PF09325.5 OAP55945.1 - 9 5.4 11.3 8.7 5.5 4.2 2.1 1 1 1 2 2 2 0 Vps5 C terminal like GRP PF07172.6 OAP55946.1 - 0.00047 20.5 17.2 0.00085 19.7 12.0 1.3 1 0 0 1 1 1 1 Glycine rich protein family ATE_C PF04377.10 OAP55947.1 - 4.1e-44 149.7 3.5 6.2e-44 149.1 2.4 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 OAP55947.1 - 6.4e-18 64.3 1.5 1.2e-17 63.4 1.0 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 OAP55947.1 - 0.042 13.7 0.8 0.094 12.6 0.6 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.23 OAP55948.1 - 8.3e-19 67.5 0.2 9.5e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain COX6B PF02297.12 OAP55949.1 - 2.2e-20 72.4 4.9 2.6e-20 72.2 3.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 OAP55949.1 - 0.0024 17.2 0.5 0.0039 16.5 0.4 1.3 1 0 0 1 1 1 1 APOBEC-like C-terminal domain RAB3GAP2_C PF14656.1 OAP55950.1 - 0.15 10.1 0.0 0.16 10.0 0.0 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RRM_1 PF00076.17 OAP55951.1 - 8.5e-14 50.9 0.0 1.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP55951.1 - 1e-09 38.0 0.0 2.6e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP55951.1 - 8e-08 32.1 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 OAP55952.1 - 1.2e-16 59.8 11.0 5.2e-06 26.1 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat SRA1 PF07304.6 OAP55952.1 - 5.8e-08 32.6 0.0 5.8e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 OAP55952.1 - 0.016 15.0 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Prp18 domain Sec16_C PF12931.2 OAP55952.1 - 0.089 12.5 0.5 0.8 9.3 0.3 2.4 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 GFO_IDH_MocA PF01408.17 OAP55953.1 - 9.6e-10 39.0 0.0 2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ammonium_transp PF00909.16 OAP55954.1 - 1.2e-109 366.4 24.8 1.4e-109 366.2 17.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Gln-synt_C PF00120.19 OAP55955.1 - 5.2e-59 199.5 0.0 6.2e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 OAP55955.1 - 4.4e-20 71.0 0.0 8.8e-20 70.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Glyco_transf_28 PF03033.15 OAP55956.1 - 7.2e-15 54.9 0.0 1.7e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 OAP55956.1 - 0.00013 20.6 0.0 0.00024 19.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 OAP55956.1 - 0.00032 20.3 0.0 0.00077 19.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 OAP55956.1 - 0.00048 20.2 0.0 0.0037 17.3 0.0 2.4 2 0 0 2 2 2 1 ATG C terminal domain HECT PF00632.20 OAP55958.1 - 2.2e-81 273.4 0.0 3.5e-81 272.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 OAP55958.1 - 0.00081 19.1 6.6 10 6.1 0.0 6.0 6 1 1 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 OAP55958.1 - 0.15 12.1 0.7 8.6 6.7 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat OAD_beta PF03977.8 OAP55958.1 - 0.32 9.6 0.0 0.57 8.8 0.0 1.3 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit CTP_transf_2 PF01467.21 OAP55959.1 - 2.7e-28 98.9 0.0 3.6e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase DUF4237 PF14021.1 OAP55959.1 - 0.0003 20.9 0.0 0.075 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4237) Ubie_methyltran PF01209.13 OAP55961.1 - 1.7e-75 253.1 0.0 1.9e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 OAP55961.1 - 5.1e-17 61.8 0.0 6.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP55961.1 - 1.2e-12 48.1 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP55961.1 - 4.1e-10 39.9 0.0 6.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP55961.1 - 9.3e-09 35.2 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP55961.1 - 1.1e-07 32.3 0.0 1.8e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP55961.1 - 5.2e-07 30.0 0.0 7.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP55961.1 - 2.5e-05 24.2 0.0 5.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 OAP55961.1 - 0.0067 16.1 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP55961.1 - 0.031 13.6 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.10 OAP55961.1 - 0.093 12.3 0.0 0.53 9.8 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase E1_dh PF00676.15 OAP55962.1 - 1.1e-87 293.5 0.0 1.4e-87 293.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 OAP55962.1 - 0.0029 17.2 0.0 0.0077 15.8 0.0 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyco_hydro_16 PF00722.16 OAP55963.1 - 2.7e-41 140.8 3.7 6.4e-41 139.6 2.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-C2H2_2 PF12756.2 OAP55964.1 - 2.7e-37 126.9 14.4 5.9e-31 106.5 2.0 3.5 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 OAP55964.1 - 2.4e-12 46.5 10.2 1.6e-07 31.2 0.7 4.1 3 1 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP55964.1 - 3.7e-07 30.1 1.1 3.7e-07 30.1 0.8 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 OAP55964.1 - 0.03 14.6 17.7 0.53 10.7 0.2 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 OAP55964.1 - 0.069 13.0 6.6 4.5 7.3 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 OAP55964.1 - 0.52 10.7 16.2 2.1 8.8 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger DUF629 PF04780.7 OAP55964.1 - 2.3 6.6 5.2 0.45 8.9 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF629) Ribosomal_L33 PF00471.15 OAP55965.1 - 2.1e-05 24.6 0.0 2.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 DivIC PF04977.10 OAP55966.1 - 0.0012 18.2 7.6 0.0012 18.2 5.3 10.6 6 4 5 12 12 12 1 Septum formation initiator Reo_sigmaC PF04582.7 OAP55966.1 - 0.048 12.8 51.2 0.0058 15.8 3.3 5.3 1 1 4 6 6 6 0 Reovirus sigma C capsid protein SKG6 PF08693.5 OAP55967.1 - 0.029 13.6 0.9 0.062 12.6 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.1 OAP55967.1 - 0.046 13.2 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2371 PF10177.4 OAP55967.1 - 0.1 12.5 0.4 0.17 11.7 0.3 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) zf-UBR PF02207.15 OAP55968.1 - 6.3e-18 64.2 12.5 1.9e-17 62.7 8.6 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 OAP55968.1 - 0.00014 21.4 0.1 0.0004 20.0 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 OAP55968.1 - 0.00065 19.4 1.0 0.00065 19.4 0.7 3.9 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 OAP55968.1 - 0.0096 15.6 0.8 0.0096 15.6 0.6 4.5 4 1 0 4 4 4 1 zinc-RING finger domain RGS-like PF09128.6 OAP55968.1 - 0.22 11.0 4.7 0.29 10.5 0.4 2.4 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain UCR_UQCRX_QCR9 PF05365.7 OAP55969.1 - 1e-25 89.0 1.9 1.2e-25 88.9 1.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Arylsulfotran_2 PF14269.1 OAP55971.1 - 4e-41 141.1 0.1 5.6e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAP55971.1 - 1.2e-12 47.0 0.1 2.4e-11 42.8 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Mago-bind PF09282.5 OAP55972.1 - 9.3e-14 50.6 2.8 2e-13 49.6 2.0 1.6 1 0 0 1 1 1 1 Mago binding Amino_oxidase PF01593.19 OAP55973.1 - 8.5e-17 61.3 1.5 1.1e-14 54.4 1.1 2.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP55973.1 - 2.2e-11 43.6 0.0 5.8e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP55973.1 - 1.9e-06 27.0 0.0 8.6e-06 24.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP55973.1 - 6e-05 22.8 0.0 0.022 14.5 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 OAP55973.1 - 6.8e-05 23.2 0.5 0.037 14.4 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP55973.1 - 0.00032 19.8 0.0 0.064 12.3 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.1 OAP55973.1 - 0.00084 19.4 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 OAP55973.1 - 0.051 11.9 0.0 0.083 11.2 0.0 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox_2 PF07992.9 OAP55973.1 - 0.052 13.4 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP55973.1 - 0.082 11.5 0.0 0.23 10.0 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.2 OAP55973.1 - 0.11 11.5 0.0 0.34 9.9 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP55973.1 - 0.15 10.5 0.0 1.5 7.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein AA_permease PF00324.16 OAP55974.1 - 3.5e-122 408.1 35.0 3.9e-122 407.9 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP55974.1 - 4.7e-33 114.3 40.4 6.5e-33 113.8 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease Vps52 PF04129.7 OAP55975.1 - 5e-121 404.7 0.0 6e-121 404.4 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 OAP55975.1 - 0.0001 20.6 4.0 0.00016 20.0 2.7 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 OAP55975.1 - 0.0023 17.9 1.2 0.0095 15.8 0.1 2.1 2 0 0 2 2 2 1 Mer2 DUF1664 PF07889.7 OAP55975.1 - 0.034 13.9 0.2 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 OAP55975.1 - 0.037 13.2 0.1 0.07 12.2 0.1 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FBP PF07299.6 OAP55975.1 - 0.084 12.1 3.7 0.11 11.8 0.6 2.2 1 1 1 2 2 2 0 Fibronectin-binding protein (FBP) COG5 PF10392.4 OAP55975.1 - 0.17 11.8 3.1 1.2 9.1 0.2 2.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 ADH_zinc_N PF00107.21 OAP55976.1 - 5.1e-25 87.5 1.8 1e-24 86.5 1.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP55976.1 - 1.1e-23 83.0 1.3 2.5e-23 81.9 0.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP55976.1 - 8.5e-05 23.4 0.0 0.00021 22.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 OAP55976.1 - 0.11 12.7 0.9 0.19 11.9 0.6 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Aldedh PF00171.17 OAP55977.1 - 3.4e-133 444.3 1.7 4.3e-133 444.0 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP55977.1 - 7.8e-05 21.5 0.0 0.00013 20.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) tRNA_m1G_MT PF01746.16 OAP55977.1 - 0.14 11.7 0.0 0.48 9.9 0.0 1.8 2 0 0 2 2 2 0 tRNA (Guanine-1)-methyltransferase FAD_binding_3 PF01494.14 OAP55978.1 - 6e-23 81.4 0.0 2.7e-22 79.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP55978.1 - 2e-08 33.5 1.3 5.8e-08 32.0 0.9 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 OAP55978.1 - 2.9e-06 26.4 6.1 0.00092 18.2 2.8 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP55978.1 - 2.8e-05 24.2 0.0 4.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP55978.1 - 0.00011 22.0 2.4 0.00029 20.8 1.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAP55978.1 - 0.00012 22.3 0.1 0.00032 21.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP55978.1 - 0.00022 20.4 0.9 0.00058 19.0 0.3 1.8 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 OAP55978.1 - 0.00048 19.7 0.2 0.001 18.6 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 OAP55978.1 - 0.00084 19.2 0.6 0.0023 17.8 0.5 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP55978.1 - 0.0012 17.4 0.1 0.0019 16.7 0.0 1.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 OAP55978.1 - 0.0014 17.5 4.7 0.0024 16.8 3.3 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 OAP55978.1 - 0.0063 15.1 1.6 0.041 12.5 0.3 2.1 1 1 0 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.19 OAP55978.1 - 0.012 14.6 0.7 0.63 9.0 0.2 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 OAP55978.1 - 0.019 14.6 0.0 0.052 13.2 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 OAP55978.1 - 0.04 12.7 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Rossmann-like PF10727.4 OAP55978.1 - 0.041 13.6 0.2 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 OAP55978.1 - 0.048 13.3 1.3 0.1 12.3 0.9 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 OAP55978.1 - 0.38 9.5 4.2 0.66 8.7 2.9 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 OAP55978.1 - 0.44 9.8 1.8 0.71 9.2 1.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MFS_1 PF07690.11 OAP55979.1 - 4.5e-29 101.2 40.4 4.5e-29 101.2 28.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 OAP55980.1 - 5.7e-66 222.9 0.0 7.1e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_4 PF13577.1 OAP55981.1 - 8.9e-07 28.8 0.4 2.1e-06 27.6 0.3 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 OAP55981.1 - 0.032 14.6 1.4 0.052 13.9 1.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 OAP55981.1 - 0.032 14.4 0.7 0.051 13.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MOSC PF03473.12 OAP55981.1 - 0.04 13.3 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 MOSC domain Fungal_trans PF04082.13 OAP55982.1 - 4.8e-33 114.1 0.1 1e-32 113.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactamase_B PF00753.22 OAP55983.1 - 1.1e-09 38.1 3.9 1.6e-09 37.6 2.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP55983.1 - 0.00019 21.0 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DSBA PF01323.15 OAP55984.1 - 3.6e-49 166.9 0.0 5.6e-26 91.3 0.0 3.0 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.1 OAP55984.1 - 0.005 16.4 0.0 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Methyltransf_23 PF13489.1 OAP55985.1 - 6.1e-23 81.3 0.0 1.5e-22 80.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP55985.1 - 4.6e-10 39.8 0.0 8.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP55985.1 - 2.4e-09 36.9 0.0 1.7e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP55985.1 - 4.3e-09 36.7 0.0 2.4e-08 34.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP55985.1 - 7e-09 36.2 0.0 1e-07 32.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP55985.1 - 0.0001 22.2 0.1 0.0016 18.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAP55985.1 - 0.00074 18.6 0.0 0.006 15.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 OAP55985.1 - 0.0009 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 OAP55985.1 - 0.0015 18.8 0.0 0.0049 17.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP55985.1 - 0.0038 16.6 0.0 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 OAP55985.1 - 0.0057 15.8 0.0 3.2 6.7 0.0 2.8 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 OAP55985.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 OAP55985.1 - 0.029 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 OAP55985.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase p450 PF00067.17 OAP55986.1 - 2.7e-53 181.1 0.0 3.6e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-5a PF01287.15 OAP55987.1 - 2.1e-27 94.8 1.2 3e-27 94.3 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 OAP55987.1 - 1.6e-05 24.4 0.7 3.1e-05 23.4 0.5 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 OAP55987.1 - 0.00088 19.0 0.8 0.019 14.8 0.0 2.5 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain Response_reg PF00072.19 OAP55987.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain RRN7 PF11781.3 OAP55988.1 - 0.0011 18.3 2.2 0.0022 17.4 1.5 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Rhodanese PF00581.15 OAP55989.1 - 2.8e-11 43.7 0.0 4.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain APH PF01636.18 OAP55990.1 - 0.0073 16.0 2.1 0.016 14.9 0.3 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family adh_short PF00106.20 OAP55992.1 - 9.2e-11 41.9 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP55992.1 - 0.00037 20.3 0.0 0.00078 19.2 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP55992.1 - 0.00038 20.1 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP55992.1 - 0.11 12.5 0.1 0.74 9.7 0.0 2.1 1 1 1 2 2 2 0 NADH(P)-binding Antistasin PF02822.9 OAP55992.1 - 2.7 8.3 6.2 1.2 9.5 1.7 2.4 3 0 0 3 3 3 0 Antistasin family p450 PF00067.17 OAP55993.1 - 1.2e-75 254.8 0.0 1.5e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 OAP55994.1 - 5e-24 85.4 7.1 5.8e-24 85.2 4.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP55994.1 - 2.3e-10 40.3 0.1 3.2e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAP55994.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Sec7 PF01369.15 OAP55995.1 - 1.8e-39 135.3 0.0 2.9e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 OAP55995.1 - 2.2e-06 27.7 0.1 5.5e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAP55995.1 - 1.4e-05 25.1 0.1 3.5e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 PH domain Dicty_REP PF05086.7 OAP55995.1 - 0.3 8.7 1.2 0.64 7.7 0.8 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PH PF00169.24 OAP55996.1 - 0.0002 21.5 0.0 0.00085 19.4 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 OAP55996.1 - 0.00027 21.0 0.0 0.00093 19.3 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Zn_clus PF00172.13 OAP55997.1 - 2.1e-07 30.7 9.6 3.1e-07 30.1 6.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_GDSL PF00657.17 OAP55997.1 - 0.04 13.7 0.1 0.056 13.2 0.1 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase SSrecog PF03531.9 OAP55998.1 - 5.5e-71 238.4 0.2 4e-48 163.6 0.0 2.4 2 0 0 2 2 2 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 OAP55998.1 - 7.9e-28 96.2 0.0 1.8e-26 91.9 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Sigma_1_2 PF03084.9 OAP55998.1 - 0.14 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family CBS PF00571.23 OAP55999.1 - 1.2e-40 137.0 5.7 7.3e-11 41.6 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 OAP55999.1 - 7.7e-11 41.5 0.0 2.9e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 PB1 domain AAA PF00004.24 OAP56000.1 - 1.3e-56 190.4 0.0 1.7e-43 147.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 OAP56000.1 - 7.3e-28 96.4 0.8 1.5e-27 95.4 0.6 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 OAP56000.1 - 1.5e-12 47.8 3.6 8.6e-07 29.1 0.0 4.1 3 1 1 4 4 3 2 AAA ATPase domain AAA_2 PF07724.9 OAP56000.1 - 8.6e-09 35.5 0.0 0.00069 19.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 OAP56000.1 - 9.1e-07 28.5 0.0 0.0038 16.9 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 OAP56000.1 - 3.3e-06 26.8 0.1 0.0037 16.9 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.1 OAP56000.1 - 8.4e-06 25.7 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 OAP56000.1 - 1.4e-05 24.0 0.0 0.011 14.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 OAP56000.1 - 1.9e-05 25.4 0.0 0.16 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 OAP56000.1 - 2.3e-05 23.9 0.1 0.067 12.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.7 OAP56000.1 - 2.7e-05 23.3 0.0 0.014 14.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 OAP56000.1 - 3e-05 24.1 0.2 0.52 10.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 OAP56000.1 - 3.2e-05 23.6 0.0 0.39 10.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 OAP56000.1 - 9.3e-05 21.6 0.0 0.27 10.3 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 OAP56000.1 - 0.00036 20.8 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 OAP56000.1 - 0.001 19.2 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 OAP56000.1 - 0.0015 18.8 0.0 1.8 8.8 0.0 2.8 2 0 0 2 2 2 1 ABC transporter Mg_chelatase PF01078.16 OAP56000.1 - 0.0016 17.6 0.0 0.69 9.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 OAP56000.1 - 0.0024 17.5 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.1 OAP56000.1 - 0.0038 16.6 4.5 2.2 7.6 0.1 4.2 2 2 2 4 4 4 1 AAA domain AAA_33 PF13671.1 OAP56000.1 - 0.0043 16.9 0.0 0.91 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAP56000.1 - 0.0057 16.7 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain cobW PF02492.14 OAP56000.1 - 0.0061 16.0 0.2 0.14 11.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 OAP56000.1 - 0.009 15.6 0.1 0.21 11.2 0.0 2.7 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 OAP56000.1 - 0.011 15.1 0.0 0.96 8.9 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 OAP56000.1 - 0.013 15.4 0.0 5.3 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 OAP56000.1 - 0.017 14.8 0.0 3 7.4 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase T2SE PF00437.15 OAP56000.1 - 0.018 13.9 0.2 0.32 9.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.5 OAP56000.1 - 0.038 13.2 0.0 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PduV-EutP PF10662.4 OAP56000.1 - 0.038 13.4 0.0 0.84 9.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Vps4_C PF09336.5 OAP56000.1 - 0.039 13.8 0.1 15 5.5 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SKI PF01202.17 OAP56000.1 - 0.06 13.2 0.0 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase KAP_NTPase PF07693.9 OAP56000.1 - 0.089 11.7 0.0 2.1 7.2 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain NB-ARC PF00931.17 OAP56000.1 - 0.098 11.4 0.0 6.1 5.6 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 OAP56000.1 - 0.1 11.6 0.0 11 5.0 0.0 2.3 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.15 OAP56000.1 - 0.11 12.1 0.1 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.8 OAP56000.1 - 0.17 10.7 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 OAP56000.1 - 0.23 10.3 0.0 4.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.13 OAP56000.1 - 0.25 10.9 0.0 16 5.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_29 PF13555.1 OAP56000.1 - 0.95 9.0 4.1 1.5 8.3 0.0 3.2 4 0 0 4 4 3 0 P-loop containing region of AAA domain MCM PF00493.18 OAP56001.1 - 2.8e-134 447.1 0.0 4.3e-134 446.4 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAP56001.1 - 1.6e-29 102.8 0.1 4.3e-29 101.4 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAP56001.1 - 6.9e-07 28.6 0.0 5.5e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAP56001.1 - 6e-06 26.0 0.0 1.8e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAP56001.1 - 0.04 13.5 0.0 0.15 11.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cyclase PF04199.8 OAP56002.1 - 2.2e-13 50.2 0.1 3.2e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase DAP3 PF10236.4 OAP56003.1 - 1.7e-73 247.2 0.0 2.3e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 OAP56003.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_S26e PF01283.14 OAP56004.1 - 9.1e-51 170.9 10.0 1.1e-50 170.6 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 OAP56004.1 - 0.011 16.1 1.7 0.13 12.6 0.3 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 OAP56004.1 - 0.023 15.0 0.1 8.2 6.8 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 OAP56004.1 - 0.036 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF2419 PF10343.4 OAP56004.1 - 0.091 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) Pkinase PF00069.20 OAP56005.1 - 1.6e-59 201.1 0.0 2.3e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56005.1 - 3.8e-28 98.2 0.0 5.6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP56005.1 - 0.035 13.0 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 OAP56005.1 - 0.14 11.9 0.1 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 OAP56006.1 - 4.3e-91 305.7 18.6 5.7e-91 305.3 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56006.1 - 1.1e-30 106.5 43.2 1.8e-20 73.0 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 OAP56006.1 - 0.18 10.2 26.9 0.062 11.7 1.1 3.0 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like COesterase PF00135.23 OAP56007.1 - 3.4e-69 233.9 1.8 6.5e-67 226.4 1.2 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP56007.1 - 1.5e-05 24.6 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP56007.1 - 0.19 10.8 0.8 0.47 9.6 0.6 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family CFEM PF05730.6 OAP56008.1 - 5.6e-07 29.2 9.0 5.6e-07 29.2 6.2 1.7 2 0 0 2 2 2 1 CFEM domain CFEM PF05730.6 OAP56010.1 - 3.4e-05 23.5 6.9 0.056 13.2 1.0 2.5 2 0 0 2 2 2 2 CFEM domain p450 PF00067.17 OAP56011.1 - 6.6e-64 216.1 0.0 1.5e-63 214.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 HAD_2 PF13419.1 OAP56012.1 - 3.8e-19 69.5 0.0 7.8e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP56012.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 OAP56012.1 - 0.039 14.3 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Methyltransf_31 PF13847.1 OAP56013.1 - 5.3e-11 42.3 0.0 2.6e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP56013.1 - 2.2e-10 40.4 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP56013.1 - 3.2e-07 30.7 0.0 6.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP56013.1 - 3.7e-07 30.5 0.0 1.1e-06 29.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP56013.1 - 1.5e-06 28.7 0.0 9.8e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP56013.1 - 3.1e-05 24.2 0.0 6.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP56013.1 - 0.0018 17.4 0.0 0.025 13.6 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 OAP56013.1 - 0.076 12.2 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 OAP56013.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 OAP56013.1 - 0.18 10.8 0.0 0.83 8.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Amidase PF01425.16 OAP56014.1 - 1.5e-89 300.9 1.4 2.9e-89 299.9 1.0 1.4 1 1 0 1 1 1 1 Amidase Aa_trans PF01490.13 OAP56015.1 - 6.9e-24 84.0 33.3 8.1e-24 83.8 23.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GWT1 PF06423.7 OAP56015.1 - 5.3 7.1 10.9 0.61 10.1 1.5 3.3 1 1 0 2 2 2 0 GWT1 Fungal_trans_2 PF11951.3 OAP56016.1 - 2.3e-17 62.6 3.6 3.4e-17 62.1 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56016.1 - 9.1e-07 28.6 5.3 1.9e-06 27.6 3.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UAF_Rrn10 PF05234.6 OAP56017.1 - 0.0008 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Arrestin_N PF00339.24 OAP56018.1 - 1.4e-10 41.1 0.5 9.8e-10 38.4 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 OAP56018.1 - 3e-07 30.6 0.0 3.6e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF3992 PF13157.1 OAP56018.1 - 0.25 11.5 4.4 0.4 10.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) Pkinase PF00069.20 OAP56019.1 - 3.9e-09 36.0 0.0 5.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 OAP56019.1 - 6.8e-06 25.4 0.0 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 OAP56019.1 - 0.00027 20.0 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 OAP56019.1 - 0.00072 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP56019.1 - 0.054 13.2 0.2 0.09 12.4 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 OAP56019.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Sec5 PF15469.1 OAP56019.1 - 0.14 11.9 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Exocyst complex component Sec5 AA_permease PF00324.16 OAP56021.1 - 7.3e-140 466.4 36.0 8.2e-140 466.2 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP56021.1 - 6.6e-42 143.5 38.4 8.9e-42 143.1 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease PMM PF03332.8 OAP56022.1 - 7.3e-97 323.2 0.0 8.8e-97 322.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 OAP56022.1 - 0.00063 19.3 0.0 0.017 14.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pico_P1A PF02226.11 OAP56022.1 - 0.0075 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Picornavirus coat protein (VP4) Trehalose_PPase PF02358.11 OAP56022.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase S6PP PF05116.8 OAP56022.1 - 0.1 11.8 0.0 3.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 OAP56022.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 OAP56023.1 - 3.4e-20 72.0 37.7 3.4e-20 72.0 26.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP56024.1 - 4.2e-12 45.4 0.0 7e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56024.1 - 1.1e-06 28.4 13.5 2.2e-06 27.4 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.9 OAP56025.1 - 3.6e-43 148.0 0.3 4.7e-43 147.7 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_3 PF01494.14 OAP56026.1 - 1.1e-18 67.3 0.3 6e-18 65.0 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP56026.1 - 7.7e-09 35.4 0.7 2.2e-08 33.9 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP56026.1 - 3.6e-07 29.4 8.3 6.7e-06 25.2 3.7 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP56026.1 - 4.2e-07 29.2 0.3 6.2e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAP56026.1 - 3.7e-06 26.9 0.1 8.5e-06 25.7 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP56026.1 - 5.9e-06 25.3 4.5 9.2e-06 24.7 2.9 1.4 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 OAP56026.1 - 5.9e-06 25.6 0.2 0.022 13.8 0.2 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 OAP56026.1 - 8.2e-06 25.1 0.3 1.1e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP56026.1 - 0.00011 22.5 0.4 0.00035 20.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP56026.1 - 0.00056 18.4 1.4 0.00085 17.9 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 OAP56026.1 - 0.001 18.0 2.2 0.001 18.0 1.5 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 OAP56026.1 - 0.0018 17.8 0.3 0.0031 17.1 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 OAP56026.1 - 0.029 14.1 0.7 0.048 13.3 0.5 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 OAP56026.1 - 0.073 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP56026.1 - 0.11 11.5 0.2 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 OAP56026.1 - 0.14 11.8 1.2 0.28 10.8 0.9 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 OAP56026.1 - 0.17 11.6 0.5 0.99 9.1 0.3 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding SSF PF00474.12 OAP56027.1 - 2.1e-15 56.3 22.0 4e-15 55.3 15.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Amidase PF01425.16 OAP56028.1 - 1.1e-93 314.4 0.0 1.3e-93 314.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 OAP56029.1 - 3.8e-33 114.6 1.0 5.3e-33 114.1 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RL11D PF11088.3 OAP56029.1 - 0.16 11.7 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 MFS_1 PF07690.11 OAP56030.1 - 8.3e-42 143.1 51.8 5.5e-41 140.4 35.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP56030.1 - 3.4e-09 35.4 21.3 1.5e-08 33.2 14.3 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 OAP56031.1 - 5.1e-72 242.8 0.0 6.5e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.12 OAP56031.1 - 0.068 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 K-box region TPPK_C PF12555.3 OAP56031.1 - 3.1 7.5 6.6 4 7.2 1.1 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Peptidase_M1 PF01433.15 OAP56032.1 - 5.6e-135 450.3 0.1 7.7e-135 449.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 OAP56032.1 - 2.4e-93 312.9 0.1 3.7e-93 312.3 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 OAP56032.1 - 3.7e-20 72.2 0.3 7.1e-20 71.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3543 PF12063.3 OAP56033.1 - 3.1e-93 311.3 0.2 4.9e-93 310.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 OAP56033.1 - 8.9e-63 211.8 0.0 1.5e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56033.1 - 3.4e-43 147.6 0.0 6.1e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP56033.1 - 0.0037 16.2 0.0 0.24 10.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 OAP56033.1 - 0.026 14.2 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CTP_transf_1 PF01148.15 OAP56034.1 - 4.9e-07 29.6 14.6 0.00086 19.0 0.9 2.9 3 0 0 3 3 3 2 Cytidylyltransferase family Taxilin PF09728.4 OAP56035.1 - 5.5e-84 281.8 59.0 5.5e-84 281.8 40.9 1.7 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF3802 PF12290.3 OAP56035.1 - 0.31 11.3 6.9 6.3 7.1 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3802) DUF1284 PF06935.6 OAP56035.1 - 2.1 8.5 11.6 0.67 10.1 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1284) CENP-B_dimeris PF09026.5 OAP56035.1 - 3.9 7.7 16.4 2.8 8.2 6.5 2.9 2 1 0 2 2 2 0 Centromere protein B dimerisation domain M16C_assoc PF08367.6 OAP56036.1 - 7.4e-52 175.6 0.0 1.1e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 OAP56036.1 - 6.9e-23 81.2 0.0 8.6e-12 45.1 0.0 3.8 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 OAP56036.1 - 3e-05 23.8 0.4 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Amidohydro_2 PF04909.9 OAP56038.1 - 5.2e-06 26.2 0.0 1.3e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase CoA_binding_2 PF13380.1 OAP56038.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Pyr_redox_3 PF13738.1 OAP56039.1 - 1.8e-16 60.8 0.0 3.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP56039.1 - 6.6e-14 51.0 0.1 2.6e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP56039.1 - 2.3e-06 26.7 0.0 5.5e-05 22.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP56039.1 - 2.7e-05 24.1 0.0 0.0013 18.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP56039.1 - 3.3e-05 23.8 0.0 0.00074 19.4 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP56039.1 - 0.00029 21.1 0.5 0.065 13.6 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP56039.1 - 0.0008 19.2 0.2 6.7 6.4 0.1 4.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 OAP56039.1 - 0.042 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP56039.1 - 0.083 13.1 0.1 4.8 7.5 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 OAP56039.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Ldh_1_C PF02866.13 OAP56039.1 - 0.13 12.0 0.3 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain APH PF01636.18 OAP56040.1 - 0.004 16.9 0.1 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Meth_synt_2 PF01717.13 OAP56041.1 - 2e-15 56.5 0.0 3.1e-13 49.3 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 OAP56041.1 - 0.00023 20.5 0.0 0.094 11.9 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain MDM31_MDM32 PF08118.6 OAP56042.1 - 7e-184 611.9 0.1 8.5e-184 611.6 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Kelch_2 PF07646.10 OAP56043.1 - 7.3e-05 22.3 6.0 0.079 12.7 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 OAP56043.1 - 0.00015 21.4 6.1 0.39 10.5 0.0 4.3 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 OAP56043.1 - 0.011 15.6 0.8 0.011 15.6 0.6 4.1 5 0 0 5 5 5 0 Kelch motif Herpes_gE PF02480.11 OAP56043.1 - 0.02 13.2 0.0 0.029 12.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Yip1 PF04893.12 OAP56043.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain Kelch_6 PF13964.1 OAP56043.1 - 4.5 7.6 12.7 2.9 8.2 0.1 4.9 3 1 2 5 5 5 0 Kelch motif KH_1 PF00013.24 OAP56044.1 - 0.00017 21.1 1.4 0.00037 20.0 1.0 1.5 1 0 0 1 1 1 1 KH domain Proteasome PF00227.21 OAP56045.1 - 1.1e-31 109.5 0.1 2.3e-31 108.5 0.0 1.5 2 0 0 2 2 2 1 Proteasome subunit Nsp1 PF11501.3 OAP56047.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 1 0 1 1 1 0 Non structural protein Nsp1 PPP4R2 PF09184.6 OAP56048.1 - 0.0051 16.3 18.3 0.0051 16.3 12.7 1.7 2 0 0 2 2 2 1 PPP4R2 CENP-T PF15511.1 OAP56048.1 - 0.009 15.3 30.0 0.012 14.8 20.8 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Daxx PF03344.10 OAP56048.1 - 0.013 14.0 29.4 0.021 13.3 20.3 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 OAP56048.1 - 0.02 12.9 24.3 0.028 12.4 16.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 OAP56048.1 - 0.2 10.6 27.0 0.24 10.4 18.7 1.1 1 0 0 1 1 1 0 BUD22 DUF2890 PF11081.3 OAP56048.1 - 0.25 11.3 21.8 0.48 10.4 15.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Hid1 PF12722.2 OAP56048.1 - 4.5 4.8 11.5 5.5 4.5 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRN3 PF05327.6 OAP56048.1 - 6.7 4.6 13.1 8.2 4.4 9.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 XAP5 PF04921.9 OAP56048.1 - 7.4 6.0 14.9 11 5.5 10.3 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator eIF-3c_N PF05470.7 OAP56048.1 - 8.2 4.3 14.6 11 4.0 10.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RGS PF00615.14 OAP56049.1 - 0.024 14.7 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Regulator of G protein signaling domain Epimerase PF01370.16 OAP56050.1 - 1e-06 28.3 0.0 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 OAP56050.1 - 1.9e-05 24.0 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP56050.1 - 0.0039 17.2 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 OAP56050.1 - 0.041 14.1 0.0 0.14 12.4 0.0 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NHase_beta PF02211.10 OAP56052.1 - 0.63 9.6 2.7 0.73 9.4 1.9 1.1 1 0 0 1 1 1 0 Nitrile hydratase beta subunit FRG2 PF15315.1 OAP56052.1 - 1.9 8.4 9.8 5.1 7.0 6.8 1.7 1 1 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Mucin PF01456.12 OAP56052.1 - 2.1 8.1 19.3 2.1 8.1 13.0 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein MAP65_ASE1 PF03999.7 OAP56052.1 - 3 6.3 4.7 2.7 6.5 3.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Exo_endo_phos PF03372.18 OAP56053.1 - 6.3e-21 75.4 0.1 9.1e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pinin_SDK_memA PF04696.8 OAP56054.1 - 7.8e-20 70.8 16.3 7.8e-20 70.8 11.3 3.7 2 2 1 3 3 3 1 pinin/SDK/memA/ protein conserved region MAP7 PF05672.6 OAP56054.1 - 0.0002 20.8 34.3 0.0002 20.8 23.8 2.7 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family PHF5 PF03660.9 OAP56055.1 - 9.4e-52 173.5 9.0 1.1e-51 173.3 6.2 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 OAP56055.1 - 0.7 9.7 14.5 0.21 11.4 4.9 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 OAP56055.1 - 1.1 9.0 15.1 3.2 7.5 0.4 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 OAP56055.1 - 8 3.9 6.4 8 3.9 4.4 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cofilin_ADF PF00241.15 OAP56056.1 - 1.5e-15 57.1 0.0 4.1e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein p450 PF00067.17 OAP56057.1 - 4.4e-60 203.5 0.0 5.7e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 OAP56058.1 - 4.5e-07 29.6 8.3 9.6e-07 28.6 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clr5 PF14420.1 OAP56059.1 - 1.6e-08 34.2 0.6 3.9e-08 33.0 0.4 1.7 1 0 0 1 1 1 1 Clr5 domain Ank_5 PF13857.1 OAP56059.1 - 2.5e-08 33.8 0.2 0.011 15.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAP56059.1 - 2.3e-07 31.0 0.0 0.05 13.9 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP56059.1 - 0.00054 20.4 0.1 2.8 8.5 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 OAP56059.1 - 0.0013 18.4 0.3 4.8 7.1 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat DUF2680 PF10925.3 OAP56059.1 - 0.041 13.7 0.4 0.1 12.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) TerY-C PF15616.1 OAP56059.1 - 0.041 13.8 0.5 0.094 12.6 0.4 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain DUF917 PF06032.7 OAP56060.1 - 4.6e-115 383.9 0.2 1e-113 379.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 OAP56060.1 - 1.4e-48 165.5 1.9 1.2e-46 159.1 0.7 2.6 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 OAP56060.1 - 2e-30 105.6 0.3 1.4e-27 96.3 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.13 OAP56060.1 - 2.5e-18 65.8 0.1 4.5e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56060.1 - 5.5e-06 26.1 7.4 1.2e-05 25.0 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MutL PF13941.1 OAP56060.1 - 3.5e-05 22.3 0.8 0.011 14.0 0.1 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 OAP56060.1 - 5e-05 22.7 0.2 0.0033 16.7 0.0 2.5 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 OAP56060.1 - 0.22 10.4 0.4 9.9 4.9 0.1 2.3 2 0 0 2 2 2 0 StbA protein Transp_cyt_pur PF02133.10 OAP56061.1 - 1.6e-97 326.8 29.1 1.8e-97 326.6 20.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 OAP56062.1 - 6e-22 77.8 27.3 6e-22 77.8 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.22 OAP56064.1 - 5.7e-71 234.3 1.9 7.6e-24 83.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Annexin PF00191.15 OAP56066.1 - 1.3e-62 207.6 2.7 2.8e-19 68.7 0.0 4.3 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 OAP56066.1 - 0.017 15.3 0.8 1.2 9.4 0.0 3.4 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TSLP PF15216.1 OAP56066.1 - 0.19 11.4 0.0 4.7 6.9 0.0 2.6 3 0 0 3 3 3 0 Thymic stromal lymphopoietin AA_permease_2 PF13520.1 OAP56068.1 - 9.1e-81 271.5 35.7 9.1e-81 271.5 24.7 1.3 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.2 OAP56069.1 - 2.6e-33 115.7 0.2 3.4e-33 115.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP56069.1 - 2e-21 76.6 0.2 7.8e-21 74.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP56069.1 - 1.4e-11 44.2 0.0 3.3e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP56069.1 - 1.8e-05 24.4 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Glyco_hydro_31 PF01055.21 OAP56070.1 - 8.8e-89 298.3 7.7 2.6e-88 296.7 5.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 CG-1 PF03859.11 OAP56070.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 CG-1 domain PP2C PF00481.16 OAP56071.1 - 6.2e-52 176.5 0.0 1.2e-51 175.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 OAP56071.1 - 2.8e-51 170.4 66.3 5e-09 35.5 0.4 12.0 5 4 9 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAP56071.1 - 5e-44 147.8 62.5 1.8e-10 40.3 1.0 12.3 6 3 9 15 15 15 10 Leucine rich repeat Guanylate_cyc PF00211.15 OAP56071.1 - 9.3e-26 90.3 0.0 3.2e-25 88.5 0.0 1.9 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 OAP56071.1 - 4.3e-22 74.7 66.4 0.047 13.7 1.0 18.8 17 2 2 19 19 19 10 Leucine Rich Repeat LRR_7 PF13504.1 OAP56071.1 - 3.4e-13 47.4 59.0 0.37 11.1 0.1 17.2 18 0 0 18 18 16 5 Leucine rich repeat RA PF00788.18 OAP56071.1 - 5.3e-11 42.8 0.0 2.6e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.6 OAP56071.1 - 1.2e-06 27.6 0.0 5.2e-06 25.6 0.0 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_6 PF13516.1 OAP56071.1 - 2.9e-05 23.6 55.1 6.8 7.0 0.1 15.8 17 1 0 17 17 16 4 Leucine Rich repeat PP2C_2 PF13672.1 OAP56071.1 - 0.0061 15.9 0.1 0.029 13.7 0.0 2.1 3 0 0 3 3 3 1 Protein phosphatase 2C LRR_9 PF14580.1 OAP56071.1 - 0.31 10.5 11.2 8.2 5.9 0.1 4.3 2 1 3 5 5 5 0 Leucine-rich repeat ATP-synt_G PF04718.10 OAP56072.1 - 9.5e-27 93.6 0.1 2.9e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF4446 PF14584.1 OAP56072.1 - 0.02 14.7 0.3 0.027 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Helicase_C PF00271.26 OAP56075.1 - 1.9e-24 85.3 0.3 5.4e-24 83.8 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP56075.1 - 2.3e-23 82.5 0.0 1e-22 80.3 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAP56075.1 - 3.3e-05 23.7 0.2 0.00017 21.4 0.0 2.1 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Bac_rhamnosid PF05592.6 OAP56076.1 - 9.7e-164 545.3 0.0 1.2e-163 545.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 OAP56076.1 - 1.7e-42 144.8 0.1 3e-42 144.0 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Clr2 PF10383.4 OAP56078.1 - 0.00011 22.1 0.2 0.00026 21.0 0.0 1.7 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Myc_N PF01056.13 OAP56078.1 - 0.16 11.0 7.3 0.27 10.3 5.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.8 OAP56078.1 - 0.85 9.1 9.7 1.5 8.4 6.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 OAP56078.1 - 2.5 6.7 16.0 4.3 5.9 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 OAP56078.1 - 4.1 6.5 7.5 7.7 5.6 5.2 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 OAP56078.1 - 8.3 6.2 7.3 0.5 10.1 1.2 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Ribosomal_L22 PF00237.14 OAP56079.1 - 8.5e-36 122.0 0.0 1.2e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RepB-RCR_reg PF10723.4 OAP56079.1 - 0.051 13.3 3.1 0.058 13.1 0.1 2.4 2 1 1 3 3 3 0 Replication regulatory protein RepB MFS_1 PF07690.11 OAP56080.1 - 3.8e-37 127.8 54.4 2.9e-32 111.7 25.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 OAP56080.1 - 0.32 10.9 4.5 0.53 10.3 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Cu_bind_like PF02298.12 OAP56081.1 - 0.071 12.9 0.2 0.19 11.5 0.1 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain DUF2057 PF09829.4 OAP56081.1 - 0.78 9.3 4.5 1.3 8.6 3.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF515 PF04415.7 OAP56081.1 - 6.3 4.9 18.7 8.9 4.4 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Fib_alpha PF08702.5 OAP56082.1 - 1.8 8.7 10.5 0.15 12.1 3.7 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 OAP56082.1 - 4.7 6.7 6.1 8.8 5.8 4.2 1.4 1 0 0 1 1 1 0 IncA protein Abhydrolase_3 PF07859.8 OAP56083.1 - 2.9e-31 108.7 0.0 3.9e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAP56083.1 - 3.7e-16 58.7 0.0 4.8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAP56083.1 - 1.3e-05 24.9 0.1 2.1e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP56083.1 - 0.092 12.1 0.2 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RRM_1 PF00076.17 OAP56084.1 - 2.4e-43 145.5 0.3 1.4e-20 72.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP56084.1 - 1.1e-33 114.9 0.1 1.8e-18 66.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 OAP56084.1 - 2.1e-28 98.3 0.2 5.3e-28 97.1 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 OAP56084.1 - 4.1e-22 77.7 0.0 2.1e-09 37.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAP56084.1 - 0.0095 15.7 0.0 0.039 13.7 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif DUF3433 PF11915.3 OAP56086.1 - 6.6e-10 39.0 3.3 6.6e-10 39.0 2.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) DUF202 PF02656.10 OAP56088.1 - 5.1e-14 52.2 3.4 7.7e-14 51.6 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) TcpE PF12648.2 OAP56088.1 - 0.61 10.2 2.8 1.1 9.3 1.9 1.4 1 0 0 1 1 1 0 TcpE family PIRT PF15099.1 OAP56088.1 - 0.77 8.9 3.0 1.9 7.7 2.1 1.6 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family Ribosomal_S8 PF00410.14 OAP56089.1 - 5.5e-25 87.6 0.1 7.8e-25 87.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DUF1995 PF09353.5 OAP56089.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1995) Ribosomal_S25 PF03297.10 OAP56090.1 - 9.2e-41 138.1 4.1 1e-40 138.0 2.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 OAP56090.1 - 0.014 15.0 0.2 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 OAP56090.1 - 0.049 13.0 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.23 OAP56091.1 - 7.6e-12 44.8 0.0 1.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NQR2_RnfD_RnfE PF03116.10 OAP56091.1 - 0.045 12.9 0.0 0.084 12.0 0.0 1.3 2 0 0 2 2 2 0 NQR2, RnfD, RnfE family Pro-rich PF15240.1 OAP56092.1 - 0.046 13.8 37.4 0.098 12.7 25.9 1.5 1 0 0 1 1 1 0 Proline-rich NMT1 PF09084.6 OAP56094.1 - 9.1e-06 25.4 0.0 0.0011 18.5 0.0 2.5 2 1 0 2 2 2 2 NMT1/THI5 like Phosphonate-bd PF12974.2 OAP56094.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 OAP56094.1 - 0.032 13.4 0.0 0.29 10.3 0.0 2.3 2 1 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Fungal_trans PF04082.13 OAP56095.1 - 2.2e-42 144.7 0.7 4.2e-42 143.8 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP56095.1 - 2.1e-37 128.6 33.6 3.7e-37 127.8 23.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP56095.1 - 1.1e-12 47.2 6.9 1.1e-12 47.2 4.8 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 OAP56095.1 - 3.6e-05 22.1 5.4 5.5e-05 21.5 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 OAP56096.1 - 7.4e-77 258.8 0.0 9.9e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.7 OAP56096.1 - 0.074 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Amido_AtzD_TrzD PF09663.5 OAP56097.1 - 1.4e-92 310.0 4.9 1.9e-92 309.6 3.4 1.2 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) GST_N_3 PF13417.1 OAP56098.1 - 6.6e-16 58.3 0.0 1.2e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP56098.1 - 4.5e-11 42.5 0.0 1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP56098.1 - 7.7e-11 42.0 0.0 1.8e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP56098.1 - 2.7e-09 36.9 0.0 4.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAP56098.1 - 7.8e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP56098.1 - 0.00044 20.6 0.1 0.00073 19.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 OAP56098.1 - 0.054 13.8 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain DUF3791 PF12668.2 OAP56098.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Zn_clus PF00172.13 OAP56099.1 - 7.6e-08 32.1 7.7 1.3e-07 31.3 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.9 OAP56100.1 - 2.3e-07 30.6 0.0 2.5e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Bac_luciferase PF00296.15 OAP56101.1 - 6.5e-57 192.9 0.2 9.7e-57 192.4 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase CPSase_L_chain PF00289.17 OAP56101.1 - 0.014 15.4 0.0 1.4 9.0 0.0 2.6 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain MFS_1 PF07690.11 OAP56102.1 - 6.3e-18 64.6 36.6 6.3e-18 64.6 25.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily AA_permease PF00324.16 OAP56103.1 - 3.5e-98 329.0 39.6 4e-98 328.8 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP56103.1 - 3.2e-28 98.4 42.8 3.9e-28 98.1 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease Spt20 PF12090.3 OAP56104.1 - 2.1e-40 138.0 0.0 2.1e-40 138.0 0.0 6.5 3 2 0 3 3 3 1 Spt20 family Cation_efflux PF01545.16 OAP56106.1 - 3e-29 101.9 4.2 3.9e-29 101.6 2.9 1.1 1 0 0 1 1 1 1 Cation efflux family DUF981 PF06168.6 OAP56106.1 - 0.028 14.1 0.3 0.051 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Bunya_NS-S PF01104.12 OAP56106.1 - 0.12 11.8 1.2 0.95 8.9 0.3 2.4 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s DUF2834 PF11196.3 OAP56106.1 - 0.6 10.2 3.6 0.3 11.2 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) RecR PF02132.10 OAP56107.1 - 0.11 11.9 0.6 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 RecR protein zinc_ribbon_4 PF13717.1 OAP56107.1 - 0.12 12.0 0.7 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain FAD_binding_3 PF01494.14 OAP56108.1 - 1.5e-18 66.9 0.1 2.8e-18 66.1 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP56108.1 - 5e-07 28.9 2.7 0.0024 16.8 1.3 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP56108.1 - 9.3e-07 28.7 0.8 2.4e-06 27.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAP56108.1 - 4.8e-06 25.9 1.2 0.036 13.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 OAP56108.1 - 1e-05 25.8 1.4 7e-05 23.1 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP56108.1 - 3.2e-05 23.1 0.3 5.2e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAP56108.1 - 5.7e-05 21.9 2.7 0.045 12.3 1.9 3.0 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 OAP56108.1 - 0.0002 21.4 0.1 0.0006 19.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP56108.1 - 0.00033 19.6 7.3 0.0016 17.3 4.9 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP56108.1 - 0.00047 20.1 1.5 0.002 18.0 1.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP56108.1 - 0.0066 15.5 0.9 0.018 14.1 0.3 1.9 2 0 0 2 2 2 1 Thi4 family SE PF08491.5 OAP56108.1 - 0.018 13.8 0.1 0.038 12.8 0.1 1.5 1 1 0 1 1 1 0 Squalene epoxidase Myosin_N PF02736.14 OAP56108.1 - 0.057 13.1 0.3 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain GIDA PF01134.17 OAP56108.1 - 0.087 11.6 3.2 0.15 10.9 2.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAP56108.1 - 0.1 11.4 2.2 6 5.6 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 OAP56108.1 - 0.21 10.0 6.1 0.11 10.9 2.9 1.4 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.13 OAP56108.1 - 0.3 10.7 1.6 2.1 7.9 0.7 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fibrillarin PF01269.12 OAP56110.1 - 1.1e-105 351.6 0.0 1.3e-105 351.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 OAP56110.1 - 4.6e-06 26.3 0.0 7.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 OAP56110.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 OAP56110.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LRR_4 PF12799.2 OAP56111.1 - 2e-43 145.3 62.8 8.4e-11 41.2 1.8 6.7 3 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAP56111.1 - 3.2e-27 94.0 53.7 7.4e-10 38.4 3.2 5.4 1 1 5 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 OAP56111.1 - 1.5e-18 63.9 36.4 0.0096 15.8 0.0 11.5 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_6 PF13516.1 OAP56111.1 - 1.7e-14 52.2 26.7 0.043 13.8 0.0 10.3 7 3 3 10 10 10 5 Leucine Rich repeat LRR_7 PF13504.1 OAP56111.1 - 1.5e-13 48.5 24.5 0.14 12.4 0.0 10.9 10 1 1 11 11 11 4 Leucine rich repeat LRR_9 PF14580.1 OAP56111.1 - 3.3e-10 39.7 11.9 4.1e-05 23.2 0.9 3.1 1 1 2 3 3 3 3 Leucine-rich repeat Phage_rep_org_N PF09681.5 OAP56111.1 - 0.19 11.2 3.3 10 5.7 0.2 2.9 1 1 2 3 3 3 0 N-terminal phage replisome organiser (Phage_rep_org_N) UB2H PF14814.1 OAP56111.1 - 0.36 10.5 1.8 27 4.5 0.0 3.8 2 1 2 4 4 4 0 Bifunctional transglycosylase second domain Sec61_beta PF03911.11 OAP56112.1 - 1.6e-19 69.3 0.4 2.4e-19 68.8 0.3 1.3 1 0 0 1 1 1 1 Sec61beta family Methyltransf_6 PF03737.10 OAP56113.1 - 6.8e-31 107.2 0.0 9.3e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Ldh_2 PF02615.9 OAP56114.1 - 4e-97 324.9 0.0 4.6e-97 324.7 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Sugar_tr PF00083.19 OAP56115.1 - 1.2e-70 238.3 22.3 1.4e-70 238.0 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56115.1 - 3.4e-16 58.9 23.1 3.4e-16 58.9 16.0 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Dabb PF07876.7 OAP56116.1 - 3.8e-13 49.7 0.2 5.7e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dak1 PF02733.12 OAP56117.1 - 5.7e-121 403.0 0.1 8.8e-121 402.4 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 OAP56117.1 - 7.2e-43 146.2 1.8 1.6e-42 145.1 0.7 1.9 2 0 0 2 2 2 1 DAK2 domain F_bP_aldolase PF01116.15 OAP56118.1 - 5.1e-92 308.0 0.0 5.7e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Amidohydro_2 PF04909.9 OAP56120.1 - 6.3e-19 68.5 0.2 3.5e-18 66.1 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase Cupin_2 PF07883.6 OAP56121.1 - 1.8e-11 43.3 0.0 0.00024 20.5 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 OAP56121.1 - 2.5e-09 36.9 0.0 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 OAP56121.1 - 4.7e-08 32.3 0.0 0.004 16.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 OAP56121.1 - 0.00064 19.3 0.0 0.44 10.1 0.0 2.4 2 0 0 2 2 2 2 Cupin EutQ PF06249.7 OAP56121.1 - 0.0057 16.2 0.0 0.0096 15.4 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Transp_cyt_pur PF02133.10 OAP56122.1 - 2.2e-22 79.2 37.3 4.3e-22 78.2 25.9 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_6 PF12697.2 OAP56124.1 - 5.1e-15 55.9 0.2 7.9e-15 55.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP56124.1 - 1.2e-09 38.0 0.0 2.9e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP56124.1 - 7e-07 29.1 0.1 1.8e-05 24.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.9 OAP56124.1 - 0.00043 18.8 0.0 0.00062 18.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family DUF3176 PF11374.3 OAP56125.1 - 9.5e-33 112.3 0.4 9.5e-33 112.3 0.3 2.7 3 1 1 4 4 4 1 Protein of unknown function (DUF3176) His_Phos_1 PF00300.17 OAP56125.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) ADH_N PF08240.7 OAP56126.1 - 1.6e-27 95.3 0.4 1.6e-27 95.3 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP56126.1 - 2.2e-15 56.3 0.0 3.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAP56127.1 - 9.9e-41 138.8 0.0 1.5e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP56127.1 - 7.3e-08 31.9 0.0 1.4e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP56127.1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_M20 PF01546.23 OAP56128.1 - 6.8e-19 68.1 0.1 9.6e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAP56128.1 - 7.9e-13 48.1 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain SET PF00856.23 OAP56129.1 - 7.6e-19 68.5 0.6 7.6e-19 68.5 0.4 3.3 3 1 0 3 3 3 1 SET domain zf-DHHC PF01529.15 OAP56130.1 - 4.7e-36 123.7 2.9 4.7e-36 123.7 2.0 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase B12D PF06522.6 OAP56131.1 - 0.026 14.2 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit SMP PF04927.7 OAP56132.1 - 0.0038 17.1 0.1 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 Seed maturation protein Coq4 PF05019.8 OAP56133.1 - 2.5e-85 284.9 0.0 2.9e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GyrI-like PF06445.10 OAP56133.1 - 0.069 13.1 0.1 0.74 9.8 0.0 2.0 2 0 0 2 2 2 0 GyrI-like small molecule binding domain dsDNA_bind PF01984.15 OAP56134.1 - 1.3e-32 111.9 10.0 1.7e-32 111.5 6.9 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 OAP56134.1 - 0.012 15.8 1.4 0.016 15.4 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) CD99L2 PF12301.3 OAP56134.1 - 0.039 13.6 3.4 1.3 8.6 0.3 2.1 2 0 0 2 2 2 0 CD99 antigen like protein 2 DUF4356 PF14266.1 OAP56134.1 - 0.073 11.4 0.1 0.083 11.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) Med4 PF10018.4 OAP56134.1 - 0.97 8.8 9.6 0.33 10.3 2.5 2.0 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 EF-1_beta_acid PF10587.4 OAP56134.1 - 1.3 9.1 9.7 1.1 9.5 0.4 3.0 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Sec2p PF06428.6 OAP56135.1 - 6.5e-28 96.5 4.0 6.5e-28 96.5 2.8 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 OAP56135.1 - 0.013 12.8 17.8 0.019 12.3 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4250 PF14056.1 OAP56135.1 - 0.023 14.4 0.0 0.086 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) AAA_13 PF13166.1 OAP56135.1 - 0.11 10.9 11.5 0.16 10.3 8.0 1.2 1 0 0 1 1 1 0 AAA domain Adeno_PX PF05829.7 OAP56135.1 - 0.15 11.6 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) tRNA-synt_2c PF01411.14 OAP56135.1 - 1.4 7.1 5.0 2 6.5 3.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Atg14 PF10186.4 OAP56135.1 - 2.2 7.1 21.7 3.5 6.4 8.1 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 OAP56135.1 - 2.3 8.6 12.0 7.5 7.0 1.3 3.5 2 1 1 3 3 3 0 SlyX IncA PF04156.9 OAP56135.1 - 3.9 7.0 23.6 4.5e+02 0.3 16.4 2.4 1 1 0 1 1 1 0 IncA protein HAUS6_N PF14661.1 OAP56135.1 - 7.5 5.8 17.1 2.9 7.1 5.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus ADIP PF11559.3 OAP56135.1 - 8.6 6.2 22.3 6.5 6.6 7.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4243 PF14027.1 OAP56136.1 - 4.2e-88 295.9 4.3 5.1e-88 295.6 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF1945 PF09178.5 OAP56136.1 - 0.085 12.7 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) Methyltransf_31 PF13847.1 OAP56137.1 - 6.5e-28 97.2 0.0 8.2e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP56137.1 - 3.5e-27 94.7 0.0 5.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP56137.1 - 6.2e-18 65.0 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP56137.1 - 1e-17 64.0 0.0 1.3e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 OAP56137.1 - 4.5e-17 62.2 0.0 6.6e-17 61.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP56137.1 - 9.3e-17 61.3 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP56137.1 - 3.1e-15 56.7 0.0 5.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 OAP56137.1 - 5.4e-11 42.2 0.0 7.1e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 OAP56137.1 - 2.2e-07 30.1 0.0 1.2e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 OAP56137.1 - 4.9e-07 29.2 0.0 6.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAP56137.1 - 5.2e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 OAP56137.1 - 3.9e-06 25.9 0.0 5.2e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_29 PF03141.11 OAP56137.1 - 5.6e-06 24.9 0.0 7.8e-06 24.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.6 OAP56137.1 - 9.6e-06 24.5 0.0 1.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.10 OAP56137.1 - 6.1e-05 22.7 0.0 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.14 OAP56137.1 - 7.3e-05 22.4 0.0 9.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.7 OAP56137.1 - 0.0014 17.9 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.6 OAP56137.1 - 0.0028 17.0 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) UPF0020 PF01170.13 OAP56137.1 - 0.0074 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CheR PF01739.13 OAP56137.1 - 0.0084 15.4 0.0 0.024 13.9 0.0 1.7 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain TehB PF03848.9 OAP56137.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.8 OAP56137.1 - 0.032 13.3 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3336 PF11815.3 OAP56138.1 - 3.2e-23 81.8 0.1 1.8e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 OAP56138.1 - 4.1e-11 43.1 0.3 1.2e-10 41.6 0.2 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase RNase_H_2 PF13482.1 OAP56138.1 - 0.065 13.0 0.5 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 RNase_H superfamily Dicty_REP PF05086.7 OAP56139.1 - 0.41 8.3 3.2 0.51 8.0 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltransf_31 PF13847.1 OAP56140.1 - 3e-20 72.3 0.0 4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP56140.1 - 2.1e-17 63.3 0.1 5.4e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP56140.1 - 4.9e-17 61.8 0.0 1.4e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 OAP56140.1 - 1.2e-14 54.8 0.1 2.3e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP56140.1 - 7.5e-14 51.7 0.0 1.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP56140.1 - 7.2e-13 48.8 0.0 1.4e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP56140.1 - 1.5e-12 47.7 0.1 4.6e-12 46.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 OAP56140.1 - 2.8e-08 33.5 0.1 9e-08 31.8 0.0 1.8 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 OAP56140.1 - 7e-08 32.5 0.3 1.9e-07 31.0 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP56140.1 - 5e-06 25.9 0.1 3.3e-05 23.3 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 OAP56140.1 - 0.00011 21.8 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 OAP56140.1 - 0.00022 20.4 0.1 0.00036 19.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 OAP56140.1 - 0.00043 19.4 0.5 0.0019 17.3 0.0 2.1 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 OAP56140.1 - 0.0073 16.3 0.3 0.035 14.1 0.2 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_3 PF01596.12 OAP56140.1 - 0.018 14.0 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 OAP56140.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.11 OAP56140.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF43 adh_short_C2 PF13561.1 OAP56141.1 - 1.5e-24 87.0 0.5 1.9e-24 86.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP56141.1 - 2.7e-22 79.4 0.2 3.4e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP56141.1 - 2.6e-05 23.9 0.2 3.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 OAP56141.1 - 0.0083 16.1 0.0 0.015 15.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP56141.1 - 0.11 12.9 0.0 0.36 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans PF04082.13 OAP56142.1 - 1.8e-20 72.9 0.1 2.7e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56142.1 - 0.003 17.4 3.1 0.0053 16.6 2.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3742 PF12553.3 OAP56142.1 - 0.22 12.0 1.8 0.67 10.4 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Sugar_tr PF00083.19 OAP56143.1 - 1.2e-87 294.4 25.5 1.3e-87 294.2 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56143.1 - 2.3e-23 82.5 32.1 6e-23 81.1 19.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP56143.1 - 0.00023 19.5 1.3 0.00023 19.5 0.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 OAP56143.1 - 0.0014 17.1 0.6 0.0014 17.1 0.4 3.6 3 1 1 4 4 4 2 MFS/sugar transport protein Pyr_redox_3 PF13738.1 OAP56144.1 - 2.7e-22 79.8 0.0 5.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP56144.1 - 3.4e-15 55.2 0.0 8.2e-15 53.9 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP56144.1 - 6.7e-06 25.2 0.0 5.5e-05 22.2 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP56144.1 - 0.0022 17.9 0.0 0.0078 16.2 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AA_permease_2 PF13520.1 OAP56145.1 - 4e-46 157.4 50.2 5.1e-46 157.0 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP56145.1 - 9.8e-24 83.5 46.1 1.3e-23 83.1 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease YrhC PF14143.1 OAP56145.1 - 3.7 7.5 13.7 8.4 6.4 0.3 4.5 4 0 0 4 4 4 0 YrhC-like protein YlaC PF10777.4 OAP56145.1 - 6.1 6.3 8.1 0.35 10.4 0.1 2.8 3 1 0 3 3 3 0 Inner membrane protein YlaC Amino_oxidase PF01593.19 OAP56146.1 - 1.1e-51 176.3 0.1 6.8e-51 173.7 0.0 2.2 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 OAP56146.1 - 8.9e-19 67.4 0.0 1.8e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 OAP56146.1 - 2.5e-13 49.8 0.2 9.4e-13 47.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP56146.1 - 1.4e-10 40.6 0.1 4.7e-08 32.3 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP56146.1 - 1.5e-06 27.3 0.5 3.7e-06 26.0 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP56146.1 - 5.2e-06 26.6 0.0 0.0021 18.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP56146.1 - 5.4e-06 25.7 0.2 8.8e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP56146.1 - 1.6e-05 24.0 0.1 0.014 14.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 OAP56146.1 - 2.8e-05 22.7 0.2 0.002 16.6 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 OAP56146.1 - 4.4e-05 22.5 1.0 7.1e-05 21.8 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 OAP56146.1 - 4.6e-05 22.6 0.0 8.3e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 OAP56146.1 - 0.00015 22.1 0.0 0.00054 20.3 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP56146.1 - 0.00038 20.3 0.1 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP56146.1 - 0.00052 19.1 0.2 0.00078 18.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 OAP56146.1 - 0.017 14.8 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans_2 PF11951.3 OAP56147.1 - 4.5e-34 117.6 0.3 6.1e-34 117.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56147.1 - 2.3e-07 30.5 6.7 4.6e-07 29.6 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 OAP56148.1 - 6.7e-06 25.3 0.2 1.4e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein KGG PF10685.4 OAP56149.1 - 0.092 12.7 6.9 0.22 11.4 4.8 1.7 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif Homeobox PF00046.24 OAP56150.1 - 7.1e-17 60.7 3.0 2.1e-16 59.2 2.1 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 OAP56150.1 - 0.0026 17.4 0.2 0.0026 17.4 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain HAD_2 PF13419.1 OAP56151.1 - 1.5e-12 48.0 0.0 3.1e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP56151.1 - 5.6e-08 33.4 0.1 2.8e-06 27.8 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP56151.1 - 2.6e-07 30.2 0.0 5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 OAP56151.1 - 0.021 14.9 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TetR_C_3 PF08362.6 OAP56151.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region GN3L_Grn1 PF08701.6 OAP56152.1 - 2.5e-24 85.0 17.2 2.5e-24 85.0 11.9 1.8 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 OAP56152.1 - 1e-19 70.6 0.0 8.2e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP56152.1 - 3.2e-06 26.5 0.0 0.00016 20.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 OAP56152.1 - 5.5e-06 25.9 0.0 0.02 14.3 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 OAP56152.1 - 2.9e-05 23.2 0.2 5e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 OAP56152.1 - 3.3e-05 24.3 0.1 0.48 10.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 OAP56152.1 - 4.7e-05 23.2 4.8 0.11 12.2 0.4 3.5 2 2 0 3 3 3 2 Dynamin family ArgK PF03308.11 OAP56152.1 - 0.024 13.4 0.0 0.024 13.4 0.0 2.1 3 0 0 3 3 3 0 ArgK protein cobW PF02492.14 OAP56152.1 - 0.099 12.0 0.0 1 8.8 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2574 PF10836.3 OAP56152.1 - 0.16 11.6 0.0 0.75 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) AAA_18 PF13238.1 OAP56152.1 - 0.32 11.3 0.0 0.32 11.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAP56152.1 - 0.4 10.6 0.1 0.4 10.6 0.0 3.2 1 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 OAP56152.1 - 0.48 11.2 0.0 0.48 11.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF2277 PF10041.4 OAP56152.1 - 0.94 9.4 3.4 14 5.7 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) CBFD_NFYB_HMF PF00808.18 OAP56153.1 - 2.7e-06 27.3 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAP56153.1 - 0.0031 17.2 0.1 0.0048 16.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 OAP56153.1 - 0.0033 17.5 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Nop14 PF04147.7 OAP56153.1 - 0.014 13.4 44.0 0.02 12.8 30.5 1.2 1 0 0 1 1 1 0 Nop14-like family Lactamase_B PF00753.22 OAP56154.1 - 6.2e-10 39.0 0.0 4e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Proteasom_Rpn13 PF04683.8 OAP56155.1 - 3.8e-25 87.7 0.0 7.7e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF1542 PF07564.6 OAP56155.1 - 0.002 18.1 0.6 0.0036 17.2 0.4 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) Ribosomal_L6e PF01159.14 OAP56156.1 - 1.9e-38 131.0 0.3 2.7e-38 130.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e FA_hydroxylase PF04116.8 OAP56157.1 - 2.8e-11 43.8 5.7 2.8e-11 43.8 3.9 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-C2H2 PF00096.21 OAP56158.1 - 3e-06 27.2 8.5 5.5e-05 23.2 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP56158.1 - 4.1e-05 23.6 9.5 0.0043 17.2 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Neur_chan_memb PF02932.11 OAP56158.1 - 0.23 11.3 1.6 0.34 10.7 1.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BCNT PF07572.7 OAP56160.1 - 7.6e-25 86.6 0.9 7.6e-25 86.6 0.6 1.8 2 0 0 2 2 2 1 Bucentaur or craniofacial development RPE65 PF03055.10 OAP56161.1 - 2.8e-110 369.1 0.0 3.1e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein ELO PF01151.13 OAP56162.1 - 1.7e-82 276.4 9.9 2.2e-82 276.1 6.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Apolipoprotein PF01442.13 OAP56162.1 - 0.0021 17.5 37.1 0.099 12.1 23.1 2.9 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain LEA_4 PF02987.11 OAP56162.1 - 0.014 15.2 1.5 0.014 15.2 1.0 4.5 4 2 1 5 5 5 0 Late embryogenesis abundant protein DUF1993 PF09351.5 OAP56162.1 - 8.6 6.2 18.3 0.095 12.6 1.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Mtc PF03820.12 OAP56163.1 - 6.4e-106 353.4 0.6 1.1e-105 352.6 0.4 1.4 1 1 0 1 1 1 1 Tricarboxylate carrier PhyH PF05721.8 OAP56164.1 - 6.4e-18 65.5 0.0 1.1e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SCP2 PF02036.12 OAP56164.1 - 0.003 17.8 0.0 0.0076 16.5 0.0 1.6 1 1 0 1 1 1 1 SCP-2 sterol transfer family 2OG-FeII_Oxy_5 PF13759.1 OAP56164.1 - 0.033 14.4 0.0 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Speriolin_C PF15059.1 OAP56164.1 - 0.2 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Speriolin C-terminus DUF3425 PF11905.3 OAP56165.1 - 2.1e-17 63.2 0.0 7e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP56165.1 - 0.00011 22.1 11.8 0.00011 22.0 4.0 2.2 1 1 1 2 2 2 1 bZIP transcription factor A_deaminase PF00962.17 OAP56166.1 - 2.5e-41 141.6 0.0 1.7e-40 138.9 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase RSN1_TM PF13967.1 OAP56166.1 - 0.074 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Mt_ATP-synt_B PF05405.9 OAP56166.1 - 0.15 11.4 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RXT2_N PF08595.6 OAP56166.1 - 2.1 8.1 6.4 4.7 6.9 4.5 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal ATG2_CAD PF13329.1 OAP56167.1 - 1.1e-35 122.5 0.0 2.6e-35 121.3 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 OAP56167.1 - 3e-28 97.8 0.3 7.7e-28 96.5 0.2 1.8 1 0 0 1 1 1 1 ATG C terminal domain VWA PF00092.23 OAP56168.1 - 1.7e-07 31.1 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 OAP56168.1 - 9e-06 25.9 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RasGEF_N PF00618.15 OAP56168.1 - 0.08 13.0 0.1 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 RasGEF N-terminal motif DUF605 PF04652.11 OAP56168.1 - 8.3 5.6 14.7 12 5.1 10.2 1.2 1 0 0 1 1 1 0 Vta1 like Raptor_N PF14538.1 OAP56169.1 - 7.2e-62 207.7 0.0 1.4e-61 206.8 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 OAP56169.1 - 2.8e-09 36.5 1.6 1.2 9.1 0.0 6.2 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 OAP56169.1 - 0.00081 19.1 0.1 0.36 10.6 0.0 2.9 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 OAP56169.1 - 0.082 13.0 3.5 0.36 11.0 0.0 3.6 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.2 OAP56169.1 - 0.23 11.3 0.2 15 5.3 0.0 2.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Kelch_5 PF13854.1 OAP56170.1 - 2.8e-33 113.3 6.3 5.2e-07 29.4 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 OAP56170.1 - 2.6e-32 110.0 1.4 2.7e-07 29.9 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 OAP56170.1 - 5.1e-32 109.4 11.6 6e-06 25.9 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 OAP56170.1 - 5.1e-32 109.2 14.9 1.5e-08 34.6 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 OAP56170.1 - 9e-27 92.1 7.1 1.4e-07 31.3 0.9 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 OAP56170.1 - 2.5e-20 71.3 4.4 7.2e-06 25.5 0.1 6.6 6 0 0 6 6 6 5 Kelch motif GAS PF13851.1 OAP56170.1 - 0.0015 17.7 9.9 0.0015 17.7 6.8 6.3 4 3 2 6 6 6 2 Growth-arrest specific micro-tubule binding RAG2 PF03089.9 OAP56170.1 - 0.013 14.2 0.0 0.41 9.3 0.0 2.7 3 0 0 3 3 3 0 Recombination activating protein 2 Filament PF00038.16 OAP56170.1 - 0.065 12.7 100.8 0.042 13.3 16.1 6.7 3 2 3 6 6 6 0 Intermediate filament protein A_deaminase PF00962.17 OAP56171.1 - 4.8e-51 173.6 0.0 5.5e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2063 PF09836.4 OAP56171.1 - 0.064 13.2 0.1 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2063) 5_nucleotid_C PF02872.13 OAP56171.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain RAI16-like PF10257.4 OAP56172.1 - 1.8e-68 231.0 0.0 3.1e-68 230.3 0.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF596 PF04591.7 OAP56172.1 - 0.2 11.6 0.0 0.51 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF596 FA_desaturase PF00487.19 OAP56173.1 - 0.19 11.1 7.3 0.22 10.9 4.6 1.3 1 1 0 1 1 1 0 Fatty acid desaturase Peptidase_M50 PF02163.17 OAP56173.1 - 0.6 9.0 7.8 0.047 12.6 1.7 1.7 2 1 0 2 2 2 0 Peptidase family M50 DUF1469 PF07332.6 OAP56173.1 - 0.92 9.2 9.9 0.55 9.9 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) CBFD_NFYB_HMF PF00808.18 OAP56174.1 - 2.7e-15 56.1 1.0 5e-15 55.2 0.7 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAP56174.1 - 3.5e-07 30.2 0.4 5.8e-07 29.5 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TSA PF03249.8 OAP56174.1 - 2.9 6.3 7.8 0.057 11.9 0.6 1.6 2 0 0 2 2 2 0 Type specific antigen Abhydrolase_3 PF07859.8 OAP56175.1 - 6.1e-22 78.2 0.0 7.6e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAP56175.1 - 1.5e-15 56.7 0.0 3.4e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Terminase_4 PF05119.7 OAP56175.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 Phage terminase, small subunit zf-RING_6 PF14835.1 OAP56176.1 - 0.0012 18.5 6.6 0.0021 17.8 4.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TPR_12 PF13424.1 OAP56177.1 - 2.4e-22 78.6 13.5 1.4e-11 44.1 0.5 4.8 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 OAP56177.1 - 1e-16 60.2 7.8 4.2e-07 29.6 0.2 6.5 5 0 0 5 5 5 4 Tetratricopeptide repeat NB-ARC PF00931.17 OAP56177.1 - 6.2e-05 21.9 0.0 0.00018 20.5 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 OAP56177.1 - 6.6e-05 23.0 0.1 0.00052 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 OAP56177.1 - 0.00021 20.9 1.2 0.17 11.8 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAP56177.1 - 0.0011 19.1 16.9 0.0028 17.9 0.7 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAP56177.1 - 0.0016 18.0 0.8 1.2 8.8 0.1 3.5 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 OAP56177.1 - 0.0036 16.9 0.0 2.3 8.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP56177.1 - 0.0068 16.1 5.4 0.026 14.3 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAP56177.1 - 0.016 14.7 0.0 0.17 11.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP56177.1 - 0.031 14.9 8.1 0.63 10.7 0.0 4.7 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP56177.1 - 0.033 14.8 12.9 0.37 11.5 0.1 6.0 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAP56177.1 - 1.2 9.2 7.9 6.5 6.9 0.1 3.9 2 1 1 4 4 4 0 Tetratricopeptide repeat Acyltransferase PF01553.16 OAP56178.1 - 0.024 14.0 0.0 0.073 12.5 0.0 1.7 1 1 0 1 1 1 0 Acyltransferase Aminotran_5 PF00266.14 OAP56180.1 - 4.5e-56 190.1 0.0 5.2e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAP56180.1 - 7.4e-06 24.4 0.0 2.4e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAP56180.1 - 4.4e-05 22.6 0.0 6.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Kinesin PF00225.18 OAP56182.1 - 5.9e-103 344.0 4.1 1.4e-102 342.9 2.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF2990 PF11693.3 OAP56182.1 - 0.091 12.6 0.4 0.68 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Filament PF00038.16 OAP56182.1 - 0.37 10.2 49.4 0.91 8.9 5.2 4.1 2 1 1 3 3 3 0 Intermediate filament protein GMC_oxred_N PF00732.14 OAP56183.1 - 2.7e-43 148.2 0.1 3.7e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP56183.1 - 8.5e-26 90.9 0.4 2.7e-25 89.3 0.3 1.9 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP56183.1 - 2.4e-08 33.2 3.1 6.6e-08 31.8 1.9 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP56183.1 - 2.8e-05 23.1 2.4 0.011 14.5 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 OAP56183.1 - 0.011 15.6 0.1 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP56183.1 - 0.021 14.8 0.1 0.064 13.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP56183.1 - 0.08 12.0 0.1 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Dus PF01207.12 OAP56184.1 - 2.2e-42 144.9 0.0 2.6e-28 98.7 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 OAP56184.1 - 0.0016 18.1 3.8 0.19 11.4 0.3 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 OAP56184.1 - 3.6 7.7 5.0 1.4 9.0 0.8 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-C2H2_4 PF13894.1 OAP56185.1 - 0.00011 22.2 11.2 0.22 11.9 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAP56185.1 - 0.0052 16.8 4.2 0.042 13.9 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 OAP56185.1 - 0.014 15.6 13.9 0.54 10.6 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP56185.1 - 0.017 15.4 0.6 0.017 15.4 0.4 3.5 4 0 0 4 4 4 0 Zinc-finger double domain Tetraspannin PF00335.15 OAP56185.1 - 0.31 10.2 2.6 3 7.0 0.1 2.2 2 0 0 2 2 2 0 Tetraspanin family KfrA_N PF11740.3 OAP56185.1 - 1.2 9.6 12.6 2 8.9 5.5 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term vMSA PF00695.14 OAP56185.1 - 1.2 8.2 14.0 5.6 6.0 0.1 2.4 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus zf-C2H2_6 PF13912.1 OAP56185.1 - 2.1 8.3 7.4 0.061 13.2 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Mg_trans_NIPA PF05653.9 OAP56186.1 - 6.1e-106 353.7 16.5 8.6e-106 353.2 11.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Choline_kinase PF01633.15 OAP56186.1 - 5.8e-56 189.4 0.0 1.5e-55 188.0 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 OAP56186.1 - 4.3e-16 58.1 0.0 9.5e-16 57.0 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus EmrE PF13536.1 OAP56186.1 - 1.7e-06 28.1 4.2 1.7e-06 28.1 2.9 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter APH PF01636.18 OAP56186.1 - 6.1e-05 22.8 0.7 6.1e-05 22.8 0.5 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family EamA PF00892.15 OAP56186.1 - 0.0018 18.3 7.6 0.0018 18.3 5.3 2.6 2 1 0 2 2 2 2 EamA-like transporter family GWT1 PF06423.7 OAP56187.1 - 1.1e-35 122.7 1.9 1.1e-35 122.7 1.3 2.3 2 0 0 2 2 2 1 GWT1 Colicin_im PF03857.8 OAP56187.1 - 4.2 7.1 13.1 0.11 12.1 0.3 3.2 3 0 0 3 3 3 0 Colicin immunity protein Fungal_trans PF04082.13 OAP56188.1 - 1.8e-11 43.4 0.2 3e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56188.1 - 2.1e-08 33.9 9.8 3.4e-08 33.2 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 OAP56189.1 - 1.5e-40 138.7 5.9 2.3e-40 138.1 4.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAP56189.1 - 2.8e-30 105.2 2.2 5.1e-30 104.3 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAP56189.1 - 9.7e-18 63.4 0.0 2.2e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAP56189.1 - 3.2e-15 56.5 1.5 3.2e-15 56.5 1.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 OAP56189.1 - 0.022 14.1 0.1 0.099 12.0 0.1 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Senescence PF06911.7 OAP56190.1 - 3.6e-49 166.8 7.2 5.6e-49 166.2 5.0 1.3 1 0 0 1 1 1 1 Senescence-associated protein Pkinase PF00069.20 OAP56191.1 - 8.8e-64 215.1 0.0 1.6e-63 214.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56191.1 - 4.1e-36 124.3 0.0 1.5e-30 106.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAP56191.1 - 2.1e-05 23.6 0.2 0.022 13.7 0.0 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 OAP56191.1 - 0.00069 19.4 0.6 0.0015 18.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family CDK5_activator PF03261.10 OAP56191.1 - 0.0057 16.0 1.3 0.019 14.3 0.9 1.9 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein RIO1 PF01163.17 OAP56191.1 - 0.0094 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 OAP56191.1 - 0.046 12.7 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_31 PF01055.21 OAP56192.1 - 5.1e-163 542.9 2.6 6.4e-163 542.6 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 OAP56192.1 - 0.018 14.8 3.2 0.024 14.4 0.1 2.9 4 0 0 4 4 4 0 Galactose mutarotase-like Borrelia_P83 PF05262.6 OAP56193.1 - 1e-06 27.3 0.0 2.4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Borrelia P83/100 protein IncA PF04156.9 OAP56194.1 - 5 6.6 7.7 28 4.2 2.4 2.6 2 0 0 2 2 2 0 IncA protein PPP4R2 PF09184.6 OAP56195.1 - 1.9e-11 44.0 1.5 1.5e-09 37.7 0.0 2.4 2 1 0 2 2 2 2 PPP4R2 GATA PF00320.22 OAP56196.1 - 5.7e-16 57.5 5.5 1e-15 56.7 3.8 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.1 OAP56196.1 - 4e-14 52.8 0.0 9.9e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 OAP56196.1 - 2.3e-13 49.9 0.0 4.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 OAP56196.1 - 2.7e-13 49.8 0.0 5.3e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 OAP56196.1 - 6.3e-11 42.2 0.0 1.3e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 OAP56196.1 - 3.6e-05 23.6 0.0 6.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 OAP56196.1 - 0.00087 19.0 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 PAS domain TF_Zn_Ribbon PF08271.7 OAP56196.1 - 0.11 11.8 0.8 0.46 9.8 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding AAA_23 PF13476.1 OAP56197.1 - 4.2e-28 99.0 3.8 4.2e-28 99.0 2.6 7.9 3 1 1 5 5 5 1 AAA domain SMC_N PF02463.14 OAP56197.1 - 2.6e-18 66.0 13.4 3.7e-09 36.1 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 OAP56197.1 - 4e-12 45.8 0.0 1.6e-11 43.9 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 OAP56197.1 - 6.4e-11 42.7 13.0 6.1e-05 23.1 2.7 3.9 2 2 0 2 2 2 2 AAA domain AAA_13 PF13166.1 OAP56197.1 - 2.1e-07 29.8 3.0 3.5e-05 22.5 0.7 7.5 3 2 2 7 7 7 3 AAA domain AAA_29 PF13555.1 OAP56197.1 - 2e-05 24.0 0.0 4.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 OAP56197.1 - 0.00034 19.7 22.3 0.0015 17.6 13.4 5.2 3 2 0 4 4 4 2 AAA ATPase domain ABC_tran PF00005.22 OAP56197.1 - 0.035 14.3 0.0 0.035 14.3 0.0 7.7 3 2 1 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 OAP56197.1 - 10 5.2 37.3 0.16 11.1 0.9 5.7 4 2 2 6 6 6 0 Reovirus sigma C capsid protein Cellulase PF00150.13 OAP56198.1 - 2.7e-20 72.7 0.7 4.1e-20 72.1 0.5 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Adap_comp_sub PF00928.16 OAP56199.1 - 2.1e-20 72.9 0.0 3.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAP56199.1 - 2.8e-08 33.5 0.0 4.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 OAP56199.1 - 0.057 13.5 0.2 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF3328 PF11807.3 OAP56200.1 - 0.0036 17.0 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TMEM52 PF14979.1 OAP56200.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Transmembrane 52 DUF2269 PF10027.4 OAP56200.1 - 0.11 12.3 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Fe_dep_repr_C PF02742.10 OAP56201.1 - 0.28 10.9 1.0 0.56 9.9 0.1 1.9 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain DUF2420 PF10336.4 OAP56202.1 - 2.3e-13 49.7 0.0 4.7e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) FTR1 PF03239.9 OAP56203.1 - 5.2e-86 288.3 5.5 6.3e-86 288.0 3.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 OAP56203.1 - 0.0062 16.5 0.3 0.0062 16.5 0.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4231) DUF3671 PF12420.3 OAP56203.1 - 0.39 10.7 0.1 0.39 10.7 0.0 2.4 3 1 0 3 3 3 0 Protein of unknown function DUF4271 PF14093.1 OAP56203.1 - 3.4 7.2 9.1 0.37 10.4 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) MgtE PF01769.11 OAP56203.1 - 5.7 7.2 7.2 25 5.1 0.5 3.1 2 1 0 2 2 2 0 Divalent cation transporter Cu-oxidase_3 PF07732.10 OAP56204.1 - 1.2e-41 141.1 5.5 2.7e-40 136.7 0.6 3.3 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP56204.1 - 2.8e-41 140.2 10.2 1.2e-37 128.5 0.4 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 OAP56204.1 - 4.7e-37 127.3 1.9 4.8e-36 124.0 0.2 2.4 2 0 0 2 2 2 1 Multicopper oxidase C1q PF00386.16 OAP56204.1 - 0.024 14.6 0.1 1 9.3 0.1 2.5 2 0 0 2 2 2 0 C1q domain Nucleos_tra2_C PF07662.8 OAP56205.1 - 2.5e-73 246.0 1.7 2.5e-73 246.0 1.2 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 OAP56205.1 - 1.7e-24 85.9 3.1 1.7e-24 85.9 2.1 2.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 OAP56205.1 - 0.0069 16.2 6.7 0.0069 16.2 4.6 3.2 3 1 1 4 4 4 1 Nucleoside recognition DUF155 PF02582.9 OAP56206.1 - 7.5e-58 195.2 0.2 1.1e-57 194.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 VIT1 PF01988.14 OAP56207.1 - 1.4e-60 204.4 3.2 2.5e-60 203.6 2.2 1.4 1 1 0 1 1 1 1 VIT family Mpv17_PMP22 PF04117.7 OAP56208.1 - 2e-16 59.3 0.4 8.5e-16 57.3 0.5 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family F-box-like PF12937.2 OAP56210.1 - 2.3e-11 43.2 0.2 5.2e-11 42.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP56210.1 - 7.8e-07 28.6 0.2 1.8e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 F-box domain Tyrosinase PF00264.15 OAP56211.1 - 9e-40 137.1 0.4 1.1e-39 136.8 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Ran_BP1 PF00638.13 OAP56212.1 - 2.7e-13 50.0 0.1 7.3e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 OAP56212.1 - 7.3e-07 29.4 1.3 7.3e-07 29.4 0.9 7.6 8 2 0 8 8 8 1 NUP50 (Nucleoporin 50 kDa) AMIN PF11741.3 OAP56212.1 - 0.071 13.0 0.6 0.71 9.8 0.1 2.3 1 1 1 2 2 2 0 AMIN domain Ribosomal_L31e PF01198.14 OAP56213.1 - 7e-38 128.1 0.7 1.1e-37 127.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 OAP56213.1 - 0.078 12.3 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel CN_hydrolase PF00795.17 OAP56214.1 - 6.9e-29 100.5 0.0 2e-28 99.0 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase UPF0254 PF06787.6 OAP56215.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Acetyltransf_1 PF00583.19 OAP56217.1 - 5.9e-09 35.8 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP56217.1 - 1.3e-07 31.7 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP56217.1 - 8.1e-05 22.7 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP56217.1 - 0.0047 16.7 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 OAP56217.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAP56217.1 - 0.0078 16.0 0.0 0.093 12.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF4190 PF13828.1 OAP56218.1 - 0.033 13.7 2.0 0.1 12.1 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) AA_permease_2 PF13520.1 OAP56219.1 - 7.8e-47 159.7 48.7 9.1e-47 159.5 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP56219.1 - 3.5e-27 94.9 39.9 4.6e-27 94.5 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_23 PF13489.1 OAP56220.1 - 1.5e-18 67.0 0.0 2.6e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP56220.1 - 7.6e-08 32.7 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP56220.1 - 1.1e-06 29.1 0.0 6.4e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP56220.1 - 3e-06 26.9 0.0 2.7e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP56220.1 - 0.00016 21.9 0.0 0.00042 20.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP56220.1 - 0.00043 20.6 0.0 0.0025 18.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP56220.1 - 0.0068 15.7 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAP56220.1 - 0.01 15.8 0.1 0.049 13.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 OAP56220.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 OAP56220.1 - 0.013 14.5 0.6 0.029 13.4 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.4 OAP56220.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Sugar_tr PF00083.19 OAP56221.1 - 1.3e-68 231.6 22.4 1.6e-63 214.8 9.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP56221.1 - 2.2e-29 102.2 24.9 4.7e-29 101.1 14.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP56221.1 - 7.4e-06 24.4 1.1 7.4e-06 24.4 0.8 2.3 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 OAP56221.1 - 0.0097 14.3 0.4 0.0097 14.3 0.3 2.9 3 1 0 3 3 3 2 MFS/sugar transport protein TauD PF02668.11 OAP56222.1 - 3.3e-36 125.2 0.0 4.1e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SNF2_N PF00176.18 OAP56223.1 - 1.4e-55 188.1 0.5 2.4e-55 187.4 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 OAP56223.1 - 1.4e-21 76.1 0.2 4.2e-21 74.6 0.2 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 OAP56223.1 - 3.1e-13 49.3 0.0 2.4e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP56223.1 - 0.0036 17.1 1.7 0.018 14.8 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 OAP56223.1 - 0.0039 16.0 0.0 0.0085 14.9 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 GFA PF04828.9 OAP56224.1 - 4e-18 65.1 0.0 5.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 OAP56224.1 - 0.19 10.9 8.7 0.42 9.8 0.0 3.1 2 1 1 3 3 3 0 zinc-ribbon domain IBR PF01485.16 OAP56225.1 - 5.9e-10 38.8 38.6 4.7e-06 26.3 7.4 3.6 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 OAP56225.1 - 0.019 14.7 10.6 0.019 14.7 7.3 3.6 2 1 1 3 3 3 0 Ring finger domain UCR_14kD PF02271.11 OAP56225.1 - 0.31 10.8 0.0 0.31 10.8 0.0 2.9 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Mu-like_Pro PF10123.4 OAP56225.1 - 1.1 8.6 5.2 0.4 10.0 1.4 1.7 2 0 0 2 2 2 0 Mu-like prophage I protein DUF498 PF04430.9 OAP56226.1 - 8.4e-22 76.8 0.0 1e-20 73.3 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Macoilin PF09726.4 OAP56226.1 - 1.1 7.4 3.5 1.2 7.2 2.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_16 PF00722.16 OAP56227.1 - 2e-42 144.5 1.3 3.5e-42 143.7 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 OAP56227.1 - 0.0097 15.8 16.6 0.022 14.7 11.5 1.6 1 0 0 1 1 1 1 Chitin recognition protein FAD_binding_3 PF01494.14 OAP56228.1 - 3.8e-45 154.4 0.0 5e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 OAP56228.1 - 0.0073 15.1 0.2 0.73 8.6 0.1 2.2 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 OAP56228.1 - 0.0079 15.1 0.0 1 8.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP56228.1 - 0.0082 14.6 0.0 0.019 13.4 0.0 1.6 1 0 0 1 1 1 1 HI0933-like protein DUF1398 PF07166.6 OAP56228.1 - 0.014 15.2 0.1 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) NAD_binding_8 PF13450.1 OAP56228.1 - 0.016 15.2 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP56228.1 - 0.023 14.5 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP56228.1 - 0.07 12.2 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 OAP56228.1 - 0.11 12.5 0.0 0.36 10.8 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP56228.1 - 0.12 11.2 0.1 0.36 9.6 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Sulfotransfer_3 PF13469.1 OAP56229.1 - 0.00045 21.1 4.5 0.0032 18.4 3.1 2.0 1 1 0 1 1 1 1 Sulfotransferase family Alk_phosphatase PF00245.15 OAP56230.1 - 1.9e-104 349.7 0.0 2.4e-104 349.3 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 OAP56230.1 - 9.9e-05 21.8 0.1 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF3545 PF12065.3 OAP56230.1 - 0.03 14.0 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) DUF1338 PF07063.8 OAP56231.1 - 2e-77 260.2 0.0 2.4e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) FAD_binding_3 PF01494.14 OAP56232.1 - 7e-22 77.9 0.0 8.8e-11 41.4 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 OAP56232.1 - 0.00018 20.4 0.0 0.0015 17.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.1 OAP56232.1 - 0.00087 19.3 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP56232.1 - 0.0087 16.0 0.2 0.033 14.2 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP56232.1 - 0.03 13.4 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 OAP56232.1 - 0.045 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 OAP56232.1 - 0.056 13.8 0.3 0.5 10.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 OAP56233.1 - 1.1e-18 67.0 0.0 1.9e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56233.1 - 9.7e-09 34.9 7.9 2.7e-08 33.5 5.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.20 OAP56234.1 - 1.6e-07 31.3 0.1 2.5e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP56234.1 - 4.2e-05 24.1 0.0 7.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain TRH PF05438.7 OAP56234.1 - 0.045 13.1 0.1 0.064 12.6 0.1 1.2 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) ADH_zinc_N PF00107.21 OAP56235.1 - 4.1e-30 103.9 0.0 7e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP56235.1 - 6.8e-18 65.7 0.0 1.2e-17 64.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP56235.1 - 1.8e-09 37.3 0.0 3.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain COesterase PF00135.23 OAP56236.1 - 1.1e-53 182.8 0.0 1.4e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP56236.1 - 8.7e-05 22.1 0.0 0.00027 20.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP56236.1 - 0.0026 17.6 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 OAP56237.1 - 2.8e-16 59.8 0.0 3.9e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56237.1 - 2.8e-10 40.3 0.0 3.5e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP56237.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 OAP56237.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.17 OAP56238.1 - 0.017 13.6 0.0 0.02 13.4 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 WD40 PF00400.27 OAP56240.1 - 5.3e-22 76.8 8.3 8.6e-09 34.9 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 OAP56240.1 - 0.00021 21.0 0.0 0.058 13.0 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ABC_tran PF00005.22 OAP56241.1 - 4.4e-33 114.4 0.0 1.2e-32 113.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 OAP56241.1 - 4.4e-30 105.0 9.9 4.4e-30 105.0 6.8 1.8 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 OAP56241.1 - 5e-06 25.9 1.3 0.00015 21.0 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP56241.1 - 3.4e-05 23.9 0.0 0.08 12.8 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP56241.1 - 0.0035 16.8 0.2 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAP56241.1 - 0.0074 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAP56241.1 - 0.033 14.1 0.1 0.12 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 OAP56241.1 - 0.04 13.8 0.5 0.5 10.3 0.3 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 OAP56241.1 - 0.07 12.5 0.1 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 OAP56241.1 - 0.071 13.2 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAP56241.1 - 0.11 11.9 0.3 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain XLF PF09302.6 OAP56242.1 - 3e-22 79.2 0.5 4.4e-22 78.6 0.3 1.2 1 0 0 1 1 1 1 XLF (XRCC4-like factor) DUF3433 PF11915.3 OAP56243.1 - 2.8e-11 43.4 2.4 6.2e-11 42.3 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) TcpE PF12648.2 OAP56243.1 - 0.043 13.9 0.8 0.072 13.2 0.1 1.7 1 1 1 2 2 2 0 TcpE family DUF1297 PF06973.7 OAP56244.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) YlaC PF10777.4 OAP56246.1 - 0.053 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 Inner membrane protein YlaC Fungal_trans PF04082.13 OAP56247.1 - 1e-18 67.1 0.4 1.7e-18 66.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cactin_mid PF10312.4 OAP56248.1 - 6.7e-67 224.4 4.8 1.1e-66 223.7 3.3 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 OAP56248.1 - 1.7e-53 179.5 2.8 3.1e-53 178.6 2.0 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein TMEM18 PF14770.1 OAP56249.1 - 2.6 7.6 6.6 6.8 6.2 1.6 2.6 2 1 0 2 2 2 0 Transmembrane protein 18 Fork_head PF00250.13 OAP56250.1 - 2.6e-11 43.3 1.2 6.2e-11 42.1 0.1 2.2 2 1 0 2 2 2 1 Fork head domain Ribosomal_L34e PF01199.13 OAP56251.1 - 2.5e-36 123.7 2.7 3.7e-36 123.2 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 OAP56251.1 - 0.24 11.0 4.0 2.5 7.8 0.2 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.6 OAP56252.1 - 7.5e-224 742.6 6.7 1.3e-223 741.8 4.6 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 OAP56252.1 - 7.8e-126 418.0 2.4 1.4e-125 417.1 1.7 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 OAP56252.1 - 2.1e-97 322.9 0.3 1.1e-62 210.1 0.2 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 OAP56252.1 - 2.3e-78 261.1 3.5 2.5e-78 261.0 1.4 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 OAP56252.1 - 2e-66 221.7 0.2 4.8e-66 220.5 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 OAP56252.1 - 6.6e-55 186.1 0.8 4.1e-53 180.3 0.0 2.5 2 0 0 2 2 2 1 Hom_end-associated Hint RRM_4 PF10598.4 OAP56252.1 - 3.7e-45 151.7 0.2 1.1e-44 150.2 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 OAP56252.1 - 7.7e-45 151.6 0.1 2.4e-44 150.0 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain Hint_2 PF13403.1 OAP56252.1 - 0.043 13.7 0.1 0.2 11.5 0.0 2.1 1 1 0 1 1 1 0 Hint domain DUF3753 PF12575.3 OAP56252.1 - 0.082 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 OAP56252.1 - 0.41 9.3 1.4 0.72 8.5 0.9 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF3425 PF11905.3 OAP56254.1 - 7.1e-19 68.0 1.7 7.1e-19 68.0 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) DUF3947 PF13135.1 OAP56254.1 - 0.21 11.8 5.7 0.3 11.3 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) ABC_tran_2 PF12848.2 OAP56254.1 - 0.96 9.3 6.5 1.7 8.5 3.6 2.1 2 1 0 2 2 2 0 ABC transporter DLH PF01738.13 OAP56255.1 - 1.8e-23 82.9 0.0 2.2e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP56255.1 - 7.7e-09 35.4 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP56255.1 - 1.7e-07 31.3 0.1 0.00017 21.5 0.1 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP56255.1 - 0.011 15.2 0.1 0.045 13.3 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Pro_dh PF01619.13 OAP56257.1 - 8.8e-42 143.1 0.7 1.2e-41 142.7 0.5 1.3 1 0 0 1 1 1 1 Proline dehydrogenase DUF4434 PF14488.1 OAP56257.1 - 0.055 13.1 0.3 0.36 10.5 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Kinesin PF00225.18 OAP56258.1 - 5.3e-116 386.9 0.0 1e-115 386.0 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Fijivirus_P9-2 PF06837.6 OAP56258.1 - 0.2 10.7 1.6 0.43 9.6 1.1 1.5 1 0 0 1 1 1 0 Fijivirus P9-2 protein AHS1 PF02682.11 OAP56258.1 - 0.27 10.6 1.5 0.47 9.8 0.2 2.0 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 PMSR PF01625.16 OAP56259.1 - 1.8e-55 187.1 0.0 2.2e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase U79_P34 PF03064.11 OAP56260.1 - 0.23 10.9 5.4 0.3 10.5 3.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3043 PF11241.3 OAP56260.1 - 1.6 8.3 7.9 1.9 8.0 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) adh_short PF00106.20 OAP56261.1 - 2.8e-17 63.1 0.0 7.6e-17 61.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP56261.1 - 1.6e-08 34.4 0.0 4.4e-07 29.7 0.0 2.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP56261.1 - 1.9e-07 31.1 0.0 3.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAP56261.1 - 0.035 13.8 0.1 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Membr_traf_MHD PF10540.4 OAP56262.1 - 4.3e-28 97.8 0.1 1.1e-26 93.2 0.2 2.8 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 OAP56262.1 - 9.5e-14 51.0 2.1 2.4e-13 49.7 0.0 2.7 3 0 0 3 3 3 1 C2 domain Pyr_redox_3 PF13738.1 OAP56263.1 - 1.2e-22 81.0 0.0 2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP56263.1 - 3.7e-11 41.9 0.0 1.2e-10 40.2 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP56263.1 - 3.9e-10 39.5 0.1 4.3e-08 33.0 0.0 3.1 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP56263.1 - 7.3e-07 28.5 0.0 0.0018 17.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.1 OAP56263.1 - 4.1e-06 25.9 0.0 0.00027 19.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAP56263.1 - 1.8e-05 23.8 0.0 0.0034 16.3 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP56263.1 - 2.7e-05 24.1 0.2 0.11 12.3 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP56263.1 - 0.00017 21.8 0.1 0.032 14.6 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP56263.1 - 0.00063 18.6 0.1 0.039 12.7 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.15 OAP56263.1 - 0.0019 18.3 0.0 0.12 12.4 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 OAP56263.1 - 0.0034 17.1 0.6 1.5 8.5 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 OAP56263.1 - 0.005 17.0 0.0 0.017 15.3 0.0 1.8 2 0 0 2 2 1 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 OAP56263.1 - 0.0062 15.4 0.1 0.62 8.9 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.17 OAP56263.1 - 0.03 13.1 0.2 2.1 7.1 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF2198 PF09964.4 OAP56263.1 - 0.071 12.8 0.2 0.97 9.2 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) HI0933_like PF03486.9 OAP56263.1 - 0.26 9.6 0.5 3.8 5.8 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.20 OAP56264.1 - 1.9e-27 96.2 2.8 4.9e-27 94.8 1.9 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56264.1 - 1.6e-10 41.2 0.0 2.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP56264.1 - 1.1e-08 35.0 3.7 1.3e-07 31.4 2.6 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP56264.1 - 0.0003 20.2 0.1 0.00047 19.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP56264.1 - 0.00045 20.2 0.5 0.0018 18.3 0.3 2.0 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 OAP56264.1 - 0.0057 15.8 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Transketolase_C PF02780.15 OAP56264.1 - 0.033 14.1 0.0 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Transketolase, C-terminal domain RmlD_sub_bind PF04321.12 OAP56264.1 - 0.04 12.7 0.1 0.058 12.2 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain VWA_2 PF13519.1 OAP56264.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain p450 PF00067.17 OAP56265.1 - 1.1e-62 212.1 0.0 1.4e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 OAP56265.1 - 9.9e-24 83.5 3.7 1.6e-23 82.8 2.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S21e PF01249.13 OAP56266.1 - 1.2e-41 140.5 0.1 1.3e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_2d PF01409.15 OAP56267.1 - 4.1e-89 298.0 0.0 5.6e-89 297.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 OAP56267.1 - 1.8e-06 26.9 0.4 0.00014 20.7 0.0 3.2 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 OAP56267.1 - 9.8e-05 22.0 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 OAP56267.1 - 0.078 12.0 0.2 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 Histidyl-tRNA synthetase MFS_1 PF07690.11 OAP56268.1 - 5.1e-57 193.1 35.7 6.7e-49 166.4 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 OAP56268.1 - 3.7 6.1 10.0 0.26 9.9 1.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF791) Zn_clus PF00172.13 OAP56269.1 - 1.8e-07 30.9 10.4 3.1e-07 30.1 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 OAP56270.1 - 0.00016 21.5 0.1 0.00033 20.5 0.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP56270.1 - 0.0058 16.4 1.7 0.014 15.1 1.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper adh_short PF00106.20 OAP56271.1 - 2.2e-24 86.2 0.8 2.6e-24 86.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP56271.1 - 5e-11 42.5 0.5 6.7e-11 42.1 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP56271.1 - 1e-09 38.5 1.0 1.3e-09 38.2 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 OAP56271.1 - 3.9e-06 25.9 0.2 4.6e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 OAP56271.1 - 2e-05 24.7 0.2 4e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 OAP56271.1 - 2.9e-05 23.6 0.5 4.8e-05 22.8 0.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 OAP56271.1 - 0.0001 21.4 0.2 0.00012 21.1 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Histidinol_dh PF00815.15 OAP56272.1 - 5.2e-174 578.7 2.6 6.8e-174 578.3 1.8 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 OAP56272.1 - 1.2e-24 85.7 0.4 2.3e-24 84.8 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 OAP56272.1 - 1.1e-11 44.8 0.3 1.1e-11 44.8 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase DUF4303 PF14136.1 OAP56272.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Fungal_trans PF04082.13 OAP56273.1 - 1.2e-10 40.7 0.1 2.6e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56273.1 - 0.0025 17.6 9.9 0.0049 16.7 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP56274.1 - 1.8e-15 56.4 0.5 4.3e-15 55.2 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56274.1 - 0.00043 20.1 6.2 0.00043 20.1 4.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_methylase PF00145.12 OAP56275.1 - 1.2e-09 37.7 0.0 6.6e-08 32.0 0.0 2.6 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase DUF2404 PF10296.4 OAP56277.1 - 0.00018 21.5 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) CN_hydrolase PF00795.17 OAP56279.1 - 1.7e-23 82.9 0.0 2.5e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CPSF_A PF03178.10 OAP56280.1 - 3.2e-97 325.4 0.0 2.1e-95 319.4 0.0 3.0 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 OAP56280.1 - 1.4e-65 221.4 0.0 2.3e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 OAP56280.1 - 0.00057 19.5 0.0 0.96 9.0 0.0 3.2 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal DUF1945 PF09178.5 OAP56280.1 - 0.13 12.1 0.0 0.5 10.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) WD40 PF00400.27 OAP56280.1 - 0.13 12.1 0.8 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat ubiquitin PF00240.18 OAP56281.1 - 6.1e-18 63.9 0.0 9.8e-18 63.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 OAP56281.1 - 9.1e-12 44.4 0.4 5.3e-11 42.0 0.1 2.5 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 OAP56281.1 - 1.5e-06 27.7 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 OAP56281.1 - 4e-05 23.4 0.1 7e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAP56281.1 - 0.0019 18.3 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain EthD PF07110.6 OAP56282.1 - 0.016 16.1 0.0 0.052 14.4 0.0 1.7 1 1 0 1 1 1 0 EthD domain WD40 PF00400.27 OAP56283.1 - 2.5e-13 49.3 2.9 0.00094 18.9 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Methyltransf_16 PF10294.4 OAP56284.1 - 9.5e-22 77.2 0.0 1.2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 OAP56284.1 - 7e-06 25.8 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP56284.1 - 0.00091 19.7 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP56284.1 - 0.017 14.4 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 OAP56284.1 - 0.019 15.0 0.0 0.025 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 OAP56284.1 - 0.025 13.9 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 OAP56286.1 - 2.4e-22 79.1 0.0 3.2e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP56286.1 - 1.4e-21 76.7 0.0 3.5e-21 75.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP56286.1 - 2.6e-16 59.7 0.0 4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP56286.1 - 1.8e-15 57.5 0.0 3.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP56286.1 - 3.2e-14 53.1 0.0 5.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP56286.1 - 8.2e-11 41.4 0.0 1.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 OAP56286.1 - 2.4e-10 40.4 0.1 6.2e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP56286.1 - 3.8e-10 40.0 0.0 7.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP56286.1 - 7.7e-09 35.1 0.0 1.6e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 OAP56286.1 - 1.6e-06 27.9 0.0 1.1e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 OAP56286.1 - 0.0016 17.5 0.0 0.013 14.5 0.0 2.0 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_9 PF08003.6 OAP56286.1 - 0.0027 16.4 0.0 0.004 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 OAP56286.1 - 0.0049 16.4 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 OAP56286.1 - 0.0084 16.1 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.7 OAP56286.1 - 0.016 14.6 0.0 0.047 13.0 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 OAP56286.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 OAP56286.1 - 0.045 12.9 0.1 0.059 12.5 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase FmrO PF07091.6 OAP56286.1 - 0.18 10.7 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF1223 PF06764.6 OAP56287.1 - 1.7e-42 145.5 0.0 3.4e-42 144.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1223) ThiS PF02597.15 OAP56288.1 - 8.8e-10 38.8 0.2 0.00019 21.7 0.0 2.1 2 0 0 2 2 2 2 ThiS family UDPGP PF01704.13 OAP56289.1 - 8.7e-186 617.4 0.4 1e-185 617.2 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase C2 PF00168.25 OAP56290.1 - 8.5e-71 233.8 1.8 2.6e-19 68.8 0.0 5.5 5 0 0 5 5 5 5 C2 domain ING PF12998.2 OAP56291.1 - 4.3e-18 65.5 4.4 4.3e-18 65.5 3.0 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 OAP56291.1 - 5.7e-10 38.7 10.3 1e-09 37.8 7.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 OAP56291.1 - 0.0021 18.1 1.7 0.0063 16.6 1.2 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 OAP56291.1 - 0.016 15.2 0.6 0.041 13.8 0.4 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 OAP56291.1 - 0.15 12.0 3.9 0.12 12.3 1.5 1.8 2 0 0 2 2 2 0 RING-like domain Hist_deacetyl PF00850.14 OAP56292.1 - 1.1e-78 264.7 0.2 1.4e-78 264.3 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RNA_pol_Rpc34 PF05158.7 OAP56293.1 - 4e-74 249.7 0.0 6.3e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 OAP56293.1 - 0.061 13.7 0.1 0.32 11.4 0.0 2.2 2 0 0 2 2 2 0 Replication protein A C terminal TPR_11 PF13414.1 OAP56294.1 - 5.1e-52 173.4 21.2 3.9e-16 58.4 0.5 6.4 3 3 5 8 8 8 8 TPR repeat TPR_1 PF00515.23 OAP56294.1 - 1.1e-46 154.6 20.7 1.1e-05 24.8 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 OAP56294.1 - 5.9e-38 125.7 21.3 0.00021 20.9 0.0 9.8 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 OAP56294.1 - 4.5e-20 71.7 11.1 0.00037 21.0 0.0 7.3 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAP56294.1 - 9.6e-17 60.7 12.6 2.2e-08 33.9 0.0 5.8 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP56294.1 - 2.6e-16 58.6 11.2 0.027 15.0 0.1 9.5 4 3 5 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAP56294.1 - 5.1e-14 52.3 12.1 0.029 14.7 1.1 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAP56294.1 - 7e-14 50.4 14.9 0.056 13.2 0.0 8.3 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAP56294.1 - 9.3e-14 50.4 5.6 0.0059 16.7 0.1 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAP56294.1 - 1.7e-10 40.6 4.2 0.003 17.3 0.0 5.3 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAP56294.1 - 8.4e-08 31.4 8.8 0.94 9.4 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 OAP56294.1 - 4.2e-06 26.8 10.0 0.036 14.1 0.5 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 OAP56294.1 - 1.4e-05 24.8 4.2 0.094 12.6 0.0 5.6 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 OAP56294.1 - 0.0017 18.6 23.4 0.4 11.2 0.0 8.5 10 0 0 10 10 7 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 OAP56294.1 - 2.9 8.1 11.7 13 5.9 0.8 4.2 5 0 0 5 5 4 0 Alkyl sulfatase dimerisation Na_H_Exchanger PF00999.16 OAP56295.1 - 7.2e-65 218.9 55.3 1.3e-64 218.0 38.4 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Coiled PF05710.7 OAP56297.1 - 7.2 7.1 7.5 0.4 11.1 0.9 2.1 2 0 0 2 2 2 0 Coiled coil UBX PF00789.15 OAP56299.1 - 8.2e-12 45.0 0.0 2.2e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 OAP56299.1 - 6.7e-11 41.5 0.0 1.8e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain HAUS6_N PF14661.1 OAP56299.1 - 3.4 6.9 11.2 5.9 6.1 7.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Pkinase PF00069.20 OAP56300.1 - 3.4e-07 29.6 0.0 5.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56300.1 - 0.0045 16.1 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mucin PF01456.12 OAP56300.1 - 0.038 13.7 13.2 0.065 12.9 9.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein LSM PF01423.17 OAP56301.1 - 2.7e-19 68.4 0.3 3.6e-19 68.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF3628 PF12300.3 OAP56301.1 - 0.42 10.6 12.3 0.59 10.1 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) FXR1P_C PF12235.3 OAP56301.1 - 6 6.9 7.9 9 6.3 5.0 1.6 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal Zn_clus PF00172.13 OAP56302.1 - 0.024 14.5 9.5 0.051 13.4 6.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.16 OAP56303.1 - 1.8e-52 177.2 0.0 2.4e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 OAP56303.1 - 9.5e-18 63.9 0.0 1.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 OAP56303.1 - 0.067 13.2 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain TauD PF02668.11 OAP56304.1 - 2e-32 112.9 0.0 2.5e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.6 OAP56304.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) MFS_1 PF07690.11 OAP56305.1 - 2.1e-31 108.9 32.7 2.1e-31 108.9 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP56305.1 - 5.8e-10 38.3 25.9 1.8e-09 36.7 18.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Xan_ur_permease PF00860.15 OAP56306.1 - 6.3e-64 215.8 31.0 1e-62 211.8 21.5 2.0 1 1 0 1 1 1 1 Permease family Sugar_tr PF00083.19 OAP56307.1 - 1.2e-81 274.6 12.9 1.4e-81 274.4 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56307.1 - 4.7e-28 97.9 16.8 6.8e-28 97.3 11.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAP56307.1 - 2.3e-05 22.9 0.4 2.3e-05 22.9 0.2 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 OAP56307.1 - 4.6e-05 21.8 0.8 4.6e-05 21.8 0.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PalH PF08733.5 OAP56307.1 - 0.42 9.3 7.2 0.093 11.5 2.7 1.6 2 0 0 2 2 2 0 PalH/RIM21 DUF2404 PF10296.4 OAP56308.1 - 3e-05 24.0 0.0 0.00011 22.3 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF1682 PF07946.9 OAP56309.1 - 1.7e-102 342.5 1.1 2.1e-102 342.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) PI-PLC-X PF00388.14 OAP56310.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Peptidase_M20 PF01546.23 OAP56311.1 - 9.1e-24 84.0 0.0 2e-22 79.6 0.0 2.7 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.27 OAP56311.1 - 2.7e-12 46.0 1.0 0.011 15.5 0.0 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat M20_dimer PF07687.9 OAP56311.1 - 2.3e-06 27.3 0.0 5.9e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.1 OAP56311.1 - 0.00034 20.7 0.1 0.13 12.5 0.0 3.0 2 0 0 2 2 2 2 PQQ-like domain Asparaginase_2 PF01112.13 OAP56312.1 - 1.7e-40 138.7 0.0 4.1e-38 130.8 0.0 2.7 3 1 0 3 3 3 2 Asparaginase Transket_pyr PF02779.19 OAP56313.1 - 1.3e-42 145.2 0.0 2.2e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAP56313.1 - 2.4e-31 108.2 0.0 5.4e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DDE_1 PF03184.14 OAP56314.1 - 1.1e-13 50.8 0.0 4.7e-07 29.1 0.0 2.6 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAP56314.1 - 7.3e-05 22.4 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain NPV_P10 PF05531.7 OAP56315.1 - 0.0012 19.0 6.0 0.61 10.3 0.0 3.4 3 1 0 3 3 3 2 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 OAP56315.1 - 0.0037 17.0 2.9 0.53 10.1 0.4 2.5 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus HemX PF04375.9 OAP56315.1 - 0.004 15.8 0.4 0.059 11.9 0.0 2.1 2 0 0 2 2 2 1 HemX DUF1319 PF07028.6 OAP56315.1 - 0.0089 16.2 0.9 0.52 10.5 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1319) AAA_13 PF13166.1 OAP56315.1 - 0.019 13.4 2.4 0.04 12.4 1.7 1.4 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.7 OAP56315.1 - 0.025 14.3 3.8 1.7 8.4 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Rootletin PF15035.1 OAP56315.1 - 0.025 14.5 0.1 0.054 13.4 0.1 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF848 PF05852.6 OAP56315.1 - 0.043 13.6 4.5 0.18 11.6 0.7 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) PMEI PF04043.10 OAP56315.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.5 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Syntaxin-6_N PF09177.6 OAP56315.1 - 0.45 10.9 5.0 13 6.3 0.6 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HSP9_HSP12 PF04119.7 OAP56315.1 - 0.63 10.1 3.1 0.46 10.6 0.2 2.0 2 1 0 2 2 2 0 Heat shock protein 9/12 SlyX PF04102.7 OAP56315.1 - 0.92 9.9 5.1 21 5.5 0.0 3.4 2 2 1 3 3 3 0 SlyX Ank_2 PF12796.2 OAP56316.1 - 3.1e-31 107.5 2.8 6.2e-12 45.6 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP56316.1 - 1.4e-27 95.5 0.6 6.9e-11 42.3 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 OAP56316.1 - 7.9e-25 85.3 3.8 4.3e-07 29.4 0.1 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 OAP56316.1 - 7.3e-13 48.3 3.5 0.00022 21.3 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP56316.1 - 8.4e-12 44.1 0.0 0.018 15.2 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat RVP PF00077.15 OAP56316.1 - 0.15 11.9 0.0 4.2 7.3 0.0 2.5 2 1 1 3 3 3 0 Retroviral aspartyl protease UPF0561 PF10573.4 OAP56318.1 - 0.13 12.0 0.5 0.5 10.2 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 HET PF06985.6 OAP56319.1 - 8.1e-19 68.1 0.2 1.9e-18 66.9 0.1 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 OAP56321.1 - 3.3e-12 46.1 0.2 7.3e-12 44.9 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56321.1 - 1.5e-06 27.4 0.0 4.1e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF21 PF01595.15 OAP56322.1 - 6.8e-34 116.7 0.2 1.1e-33 116.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 OAP56322.1 - 8.3e-07 28.6 0.5 0.0026 17.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain FA_desaturase PF00487.19 OAP56323.1 - 0.51 9.7 4.0 0.87 8.9 2.7 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Reo_sigmaC PF04582.7 OAP56323.1 - 1.4 8.0 13.8 0.75 8.9 0.2 3.9 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Glyco_hydro_15 PF00723.16 OAP56324.1 - 5.7e-51 173.4 0.0 2.1e-47 161.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.11 OAP56325.1 - 1.3e-31 109.2 15.5 1.3e-31 109.2 10.7 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 OAP56325.1 - 1.1e-07 31.0 29.1 2.7e-05 23.2 18.1 2.1 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.15 OAP56325.1 - 0.00088 19.3 35.6 0.058 13.4 9.8 2.8 2 1 0 2 2 2 2 EamA-like transporter family Plasmodium_Vir PF05795.6 OAP56325.1 - 0.35 10.0 1.7 4.4 6.4 0.0 2.6 3 0 0 3 3 3 0 Plasmodium vivax Vir protein DUF2207 PF09972.4 OAP56325.1 - 2.9 6.3 0.0 2.9 6.3 0.0 3.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3949 PF13133.1 OAP56325.1 - 6 7.1 5.4 41 4.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) HET PF06985.6 OAP56326.1 - 4.2e-21 75.5 0.0 9.2e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 OAP56326.1 - 1.8e-17 63.7 0.0 3.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56326.1 - 1.2e-07 31.7 0.0 2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP56326.1 - 2.8e-05 23.8 0.0 9.1e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP56326.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B PF00753.22 OAP56327.1 - 1.8e-20 73.4 0.0 2.3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP56327.1 - 2.6e-06 27.0 0.3 5.1e-06 26.1 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP56327.1 - 0.025 14.2 0.0 0.083 12.5 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Metallophos_2 PF12850.2 OAP56327.1 - 0.12 12.2 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain AD PF09793.4 OAP56330.1 - 2.1e-12 46.7 0.0 3.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain 6PGD PF00393.14 OAP56331.1 - 7.9e-134 445.4 0.0 1e-133 445.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 OAP56331.1 - 5e-51 172.7 0.0 7.3e-51 172.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP56331.1 - 0.029 14.4 0.9 0.064 13.3 0.0 2.0 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.17 OAP56332.1 - 1.7e-18 65.9 0.0 2.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP56332.1 - 3.9e-11 42.7 0.0 6.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP56332.1 - 0.00093 18.9 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 OAP56332.1 - 0.052 13.0 0.1 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain Peptidase_C2 PF00648.16 OAP56333.1 - 5.1e-57 193.1 2.1 3.7e-39 134.5 0.3 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease MIP-T3 PF10243.4 OAP56333.1 - 0.051 12.0 29.4 0.095 11.1 20.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SET PF00856.23 OAP56333.1 - 0.07 13.4 1.6 0.74 10.0 0.5 2.4 2 0 0 2 2 2 0 SET domain DDHD PF02862.12 OAP56333.1 - 5.6 6.6 7.6 11 5.6 5.3 1.5 1 0 0 1 1 1 0 DDHD domain Sugar_tr PF00083.19 OAP56334.1 - 1.6e-74 251.1 26.2 1.9e-74 250.9 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56334.1 - 7.4e-16 57.8 32.4 7.4e-16 57.8 22.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3906 PF13046.1 OAP56334.1 - 0.0066 16.0 0.1 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3906) tRNA-synt_1b PF00579.20 OAP56335.1 - 1.3e-63 214.8 0.0 1.7e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase PF00069.20 OAP56336.1 - 3.8e-71 239.2 0.0 4.7e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56336.1 - 6.8e-31 107.2 0.0 8.9e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP56336.1 - 0.00017 20.6 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAP56336.1 - 0.0065 16.2 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAP56336.1 - 0.0097 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 OAP56336.1 - 0.14 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2C_adapt PF08793.5 OAP56337.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain DUF2207 PF09972.4 OAP56337.1 - 0.14 10.7 0.0 0.14 10.7 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3180 PF11377.3 OAP56337.1 - 0.4 10.5 8.1 1.5 8.7 5.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) MASE1 PF05231.9 OAP56337.1 - 7.5 5.4 14.0 0.058 12.3 1.1 2.5 2 1 0 2 2 2 0 MASE1 DUF1625 PF07787.7 OAP56337.1 - 8.4 5.5 7.7 11 5.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1625) Peptidase_S28 PF05577.7 OAP56338.1 - 5e-39 134.0 0.4 1e-37 129.7 0.3 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 OAP56338.1 - 4.1e-11 42.4 0.0 2e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAP56338.1 - 4e-05 23.6 0.0 0.00015 21.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP56338.1 - 0.00011 21.9 0.1 0.00087 19.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2920 PF11144.3 OAP56338.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PTR2 PF00854.16 OAP56339.1 - 2.1e-44 151.8 9.0 5.4e-44 150.4 6.3 1.7 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 OAP56339.1 - 6.2e-06 25.1 29.1 1e-05 24.4 18.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily RVP_2 PF08284.6 OAP56340.1 - 0.071 13.0 0.1 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Retroviral aspartyl protease Isochorismatase PF00857.15 OAP56341.1 - 6.1e-20 71.8 0.0 8.5e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DsrH PF04077.7 OAP56341.1 - 0.11 12.1 0.1 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 DsrH like protein NOC3p PF07540.6 OAP56343.1 - 1.2e-29 102.4 0.7 1.4e-28 98.9 0.0 2.7 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 OAP56343.1 - 1.1e-20 73.6 0.1 5e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 CBF/Mak21 family UPF0113 PF03657.8 OAP56344.1 - 9.4e-08 31.8 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 OAP56344.1 - 0.029 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 PUA domain ApoO PF09769.4 OAP56345.1 - 2.8e-46 157.1 0.5 6.6e-46 155.9 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O DehI PF10778.4 OAP56345.1 - 0.044 13.3 0.1 0.073 12.5 0.1 1.3 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI Glyco_hydro_43 PF04616.9 OAP56346.1 - 8.3e-72 241.6 0.2 1.1e-71 241.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FMO-like PF00743.14 OAP56347.1 - 5.7e-23 80.9 0.0 1e-12 47.0 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAP56347.1 - 3.4e-16 59.9 0.0 3.1e-15 56.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP56347.1 - 4.2e-07 29.8 0.0 1.5e-06 28.1 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP56347.1 - 9.9e-07 28.6 0.2 2.8e-05 23.9 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAP56347.1 - 3.2e-05 23.0 0.8 0.02 13.8 0.0 3.7 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP56347.1 - 3.6e-05 23.7 0.1 0.28 11.0 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP56347.1 - 0.0003 19.7 0.1 0.023 13.5 0.4 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP56347.1 - 0.0056 15.7 0.1 0.018 14.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family TPP_enzyme_M PF00205.17 OAP56347.1 - 0.017 14.8 0.1 0.043 13.5 0.0 1.6 2 0 0 2 2 1 0 Thiamine pyrophosphate enzyme, central domain Shikimate_DH PF01488.15 OAP56347.1 - 0.028 14.5 0.1 1.8 8.6 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 OAP56347.1 - 0.06 12.1 0.8 0.11 11.3 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 OAP56347.1 - 0.062 13.7 0.1 0.45 10.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP56347.1 - 0.063 11.7 0.8 0.1 11.0 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 OAP56347.1 - 0.099 12.3 0.2 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OCD_Mu_crystall PF02423.10 OAP56347.1 - 0.1 11.3 0.1 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GIDA PF01134.17 OAP56347.1 - 0.21 10.4 1.3 0.29 9.9 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Peptidase_M3 PF01432.15 OAP56349.1 - 1.3e-114 383.8 0.0 1.8e-114 383.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 O-FucT PF10250.4 OAP56349.1 - 0.0018 17.4 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Fungal_trans PF04082.13 OAP56350.1 - 1.1e-09 37.5 0.0 1.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.7 OAP56350.1 - 0.63 10.2 4.1 1.4 9.1 2.9 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Methyltransf_11 PF08241.7 OAP56351.1 - 2.1e-16 60.1 0.0 4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP56351.1 - 8.3e-11 42.2 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP56351.1 - 4.8e-09 36.7 0.0 1.2e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP56351.1 - 6.5e-09 35.7 0.0 1.5e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP56351.1 - 1.6e-08 34.3 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP56351.1 - 1.7e-07 31.5 0.0 3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP56351.1 - 6.1e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP56351.1 - 0.00049 19.2 0.0 0.00086 18.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Zn_clus PF00172.13 OAP56352.1 - 8.5e-08 31.9 11.3 1.5e-07 31.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin PF00085.15 OAP56354.1 - 4.2e-62 206.3 1.0 3e-30 103.9 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 OAP56354.1 - 1.3e-53 181.5 0.0 1.3e-38 132.6 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAP56354.1 - 1.3e-11 44.4 0.1 0.0026 17.8 0.0 4.7 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.1 OAP56354.1 - 2.1e-10 40.8 1.6 0.00065 19.8 0.1 3.9 2 2 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 OAP56354.1 - 6.6e-09 35.6 2.3 0.003 17.5 0.0 3.7 5 0 0 5 5 5 2 Thioredoxin-like Redoxin PF08534.5 OAP56354.1 - 1.6e-08 34.2 1.7 0.0068 15.9 0.0 3.7 3 1 0 3 3 3 3 Redoxin Calsequestrin PF01216.12 OAP56354.1 - 2.2e-08 33.3 0.5 5.1e-08 32.1 0.1 1.7 1 1 1 2 2 2 1 Calsequestrin AhpC-TSA PF00578.16 OAP56354.1 - 6.7e-08 32.2 1.5 0.028 14.1 0.0 4.3 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_4 PF13462.1 OAP56354.1 - 0.00011 22.2 0.4 0.072 13.0 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_9 PF14595.1 OAP56354.1 - 0.019 14.5 0.1 1.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin DUF2414 PF10309.4 OAP56354.1 - 0.077 12.6 0.0 13 5.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2414) ATG22 PF11700.3 OAP56355.1 - 2.2e-209 695.8 11.0 2.6e-209 695.6 7.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 OAP56355.1 - 8e-07 28.0 52.3 1.4e-05 23.9 16.2 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Med14 PF08638.6 OAP56356.1 - 2.2e-62 209.8 0.0 4.8e-62 208.6 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 UDG PF03167.14 OAP56357.1 - 3.8e-26 91.3 0.0 5.9e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Zn_clus PF00172.13 OAP56358.1 - 4e-10 39.4 9.0 8.2e-10 38.4 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP56358.1 - 0.0022 16.9 0.2 0.014 14.2 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_20 PF00728.17 OAP56359.1 - 3.8e-97 325.5 1.4 8.4e-97 324.4 0.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 OAP56359.1 - 1.1e-17 64.8 0.1 3.7e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 OAP56359.1 - 0.0006 20.3 0.1 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 MmgE_PrpD PF03972.9 OAP56360.1 - 9.4e-71 238.2 0.0 1.1e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Abhydrolase_6 PF12697.2 OAP56362.1 - 4.6e-21 75.7 0.2 1e-20 74.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP56362.1 - 2.6e-08 33.7 0.0 5.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP56362.1 - 8.1e-08 32.0 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAP56362.1 - 1.1e-06 28.3 0.0 1.3e-05 24.9 0.0 2.3 1 1 1 2 2 2 1 Putative lysophospholipase Ephrin_lbd PF01404.14 OAP56362.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain GMC_oxred_N PF00732.14 OAP56363.1 - 1.5e-54 185.1 0.0 2e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP56363.1 - 9.4e-23 81.0 0.0 1.8e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAP56363.1 - 8.5e-09 34.7 3.6 0.00056 18.8 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP56363.1 - 0.00013 21.0 0.7 0.003 16.5 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP56363.1 - 0.00043 19.3 0.1 0.00062 18.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP56363.1 - 0.001 19.0 2.0 0.0017 18.3 0.6 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP56363.1 - 0.0013 18.6 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP56363.1 - 0.0027 17.7 0.0 0.053 13.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP56363.1 - 0.0039 16.3 1.2 0.022 13.8 0.2 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 OAP56363.1 - 0.0085 14.6 0.2 0.013 13.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 OAP56363.1 - 0.019 15.3 0.5 0.64 10.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP56363.1 - 0.028 13.2 0.6 3.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 OAP56363.1 - 0.072 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase SH3_5 PF08460.5 OAP56363.1 - 0.072 13.0 0.2 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Caleosin PF05042.8 OAP56364.1 - 1.7e-56 190.4 0.0 2.2e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 OAP56364.1 - 5.5e-06 25.8 0.7 0.0041 16.8 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 OAP56364.1 - 6.1e-05 22.0 1.0 0.0056 15.9 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 OAP56364.1 - 0.00012 22.0 0.4 0.016 15.3 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 OAP56364.1 - 0.051 13.2 0.7 0.69 9.5 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 OAP56364.1 - 0.33 10.3 6.3 2.1 7.8 0.0 3.3 3 0 0 3 3 3 0 EF hand Aminotran_1_2 PF00155.16 OAP56365.1 - 2e-35 122.4 0.0 2.6e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 OAP56365.1 - 0.086 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Beta_elim_lyase PF01212.16 OAP56365.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Sugar_tr PF00083.19 OAP56366.1 - 1.9e-72 244.3 21.9 2.2e-72 244.0 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56366.1 - 2.5e-19 69.1 64.8 2.2e-17 62.8 26.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HD_4 PF13328.1 OAP56366.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 HD domain Cyclase PF04199.8 OAP56367.1 - 2.4e-10 40.3 0.0 3.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.13 OAP56368.1 - 1.5e-15 56.8 0.1 3e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.13 OAP56369.1 - 1.6e-108 362.7 0.0 2.2e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAP56369.1 - 8.6e-21 73.5 0.1 3.5e-20 71.5 0.0 2.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAP56369.1 - 0.00012 21.1 0.3 0.00025 20.1 0.0 1.6 1 1 1 2 2 2 1 Conserved region in glutamate synthase ThiG PF05690.9 OAP56369.1 - 0.0013 17.8 0.1 0.06 12.4 0.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 OAP56369.1 - 0.0046 15.8 0.2 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 OAP56369.1 - 0.0059 15.8 0.3 0.0092 15.1 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase FAD_binding_3 PF01494.14 OAP56370.1 - 2.9e-46 158.1 0.0 5.5e-46 157.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP56370.1 - 0.00069 19.5 0.0 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP56370.1 - 0.0017 17.3 0.0 0.19 10.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 OAP56370.1 - 0.0021 17.0 0.0 0.31 9.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP56370.1 - 0.0059 16.9 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP56370.1 - 0.0095 16.0 0.0 0.033 14.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP56370.1 - 0.012 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 OAP56370.1 - 0.027 13.8 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 OAP56370.1 - 0.036 12.5 0.0 0.081 11.3 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.5 OAP56370.1 - 0.065 12.0 0.0 3.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Sugar_tr PF00083.19 OAP56371.1 - 1.3e-82 277.7 18.6 1.7e-82 277.3 12.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56371.1 - 3.5e-31 108.1 31.3 6.8e-31 107.2 21.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP56371.1 - 0.0002 19.7 4.8 0.0002 19.7 3.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 OAP56371.1 - 0.0002 19.9 0.3 0.00032 19.3 0.2 1.2 1 0 0 1 1 1 1 Reduced folate carrier DUF1228 PF06779.9 OAP56371.1 - 0.37 10.8 9.5 1.6 8.8 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Abhydrolase_5 PF12695.2 OAP56372.1 - 9.6e-10 38.3 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP56372.1 - 0.014 14.6 0.0 0.035 13.3 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.6 OAP56372.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 OAP56372.1 - 0.027 13.7 0.1 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Carboxyl_trans PF01039.17 OAP56373.1 - 3.2e-57 193.9 0.0 6.5e-48 163.3 0.0 2.6 1 1 1 2 2 2 2 Carboxyl transferase domain adh_short PF00106.20 OAP56375.1 - 8.1e-24 84.4 0.1 1.6e-23 83.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56375.1 - 2.7e-13 50.2 0.0 3.7e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP56375.1 - 4.9e-12 45.8 0.0 6.2e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP56375.1 - 1.6e-05 25.0 0.0 3.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 OAP56375.1 - 0.0078 15.2 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 OAP56375.1 - 0.019 13.8 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aminotran_1_2 PF00155.16 OAP56376.1 - 9.4e-40 136.6 0.0 1.2e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAP56376.1 - 1.3e-07 30.3 0.0 1.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 OAP56376.1 - 2.4e-06 26.5 0.0 7.9e-06 24.8 0.0 1.8 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 OAP56376.1 - 0.0019 17.4 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.8 OAP56376.1 - 0.0028 16.3 0.0 0.012 14.3 0.0 1.9 2 0 0 2 2 2 1 Allinase DegT_DnrJ_EryC1 PF01041.12 OAP56376.1 - 0.018 14.0 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 OAP56377.1 - 3.1e-17 62.3 0.3 8.4e-17 60.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.15 OAP56378.1 - 3.7e-37 128.7 0.0 4.4e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAP56378.1 - 4.9e-20 72.7 0.1 1.1e-18 68.2 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 OAP56378.1 - 3.2e-13 49.2 0.1 1.4e-12 47.1 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP56378.1 - 3.1e-11 43.1 0.2 1.4e-07 31.1 0.0 2.7 2 2 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.11 OAP56379.1 - 2.7e-31 108.5 30.9 2.7e-31 108.5 21.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 OAP56380.1 - 1.7e-14 53.6 0.1 2.9e-14 52.8 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 NACHT PF05729.7 OAP56381.1 - 7.7e-11 41.9 0.0 2.3e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 OAP56381.1 - 2.2e-06 27.8 0.0 0.00018 21.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain zf-C2H2_4 PF13894.1 OAP56381.1 - 2.5e-06 27.4 15.1 0.012 15.9 1.3 5.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP56381.1 - 3.4e-06 27.0 18.0 0.033 14.5 2.1 4.6 5 0 0 5 5 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 OAP56381.1 - 0.00019 21.2 3.1 0.26 11.2 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger AAA_16 PF13191.1 OAP56381.1 - 0.00061 19.8 0.0 0.00061 19.8 0.0 4.3 5 0 0 5 5 5 1 AAA ATPase domain AAA_14 PF13173.1 OAP56381.1 - 0.00063 19.6 0.1 0.11 12.3 0.0 3.8 2 1 0 2 2 2 1 AAA domain zf-H2C2_2 PF13465.1 OAP56381.1 - 0.0007 19.7 0.2 0.0007 19.7 0.2 4.9 5 1 0 5 5 4 1 Zinc-finger double domain NB-ARC PF00931.17 OAP56381.1 - 0.00082 18.3 0.0 0.0053 15.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 OAP56381.1 - 0.00094 19.3 0.0 0.014 15.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 OAP56381.1 - 0.0019 17.2 0.0 0.0063 15.5 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 OAP56381.1 - 0.0054 15.7 0.1 0.024 13.6 0.0 2.0 3 0 0 3 3 3 1 KAP family P-loop domain AAA_19 PF13245.1 OAP56381.1 - 0.0066 16.1 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 OAP56381.1 - 0.01 16.1 0.0 0.37 11.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAP56381.1 - 0.017 15.2 0.0 0.09 12.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 OAP56381.1 - 0.024 14.1 0.3 5.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 OAP56381.1 - 0.049 13.0 0.2 0.31 10.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain zf-met PF12874.2 OAP56381.1 - 1.6 9.0 6.6 44 4.4 0.8 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type SNF2_N PF00176.18 OAP56382.1 - 7.6e-64 215.3 0.0 1.1e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP56382.1 - 6.6e-10 38.7 0.0 1.7e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP56382.1 - 4.2e-06 26.3 0.0 8.4e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAP56382.1 - 4.3e-06 26.6 0.0 1.4e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.1 OAP56382.1 - 0.0037 16.7 3.8 0.0092 15.5 2.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.1 OAP56382.1 - 0.015 14.9 5.5 0.033 13.8 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP56382.1 - 0.018 14.7 6.4 0.038 13.7 4.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DEAD_2 PF06733.10 OAP56382.1 - 0.022 14.1 0.0 0.065 12.6 0.0 1.7 2 0 0 2 2 2 0 DEAD_2 zf-RING_6 PF14835.1 OAP56382.1 - 0.31 10.8 7.1 0.62 9.8 2.1 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 OAP56382.1 - 1.5 8.9 6.7 3.8 7.6 4.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1275 PF06912.6 OAP56383.1 - 1.9e-44 151.4 18.1 2.2e-44 151.1 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Fungal_trans PF04082.13 OAP56384.1 - 1.1e-12 47.3 0.1 1.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.24 OAP56385.1 - 6.2e-17 62.0 0.0 1.8e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP56385.1 - 0.017 15.2 0.0 0.071 13.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain SET PF00856.23 OAP56386.1 - 8.2e-10 39.2 0.0 2.2e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 OAP56386.1 - 4e-08 33.0 10.4 4e-08 33.0 7.2 3.0 3 0 0 3 3 3 1 MYND finger Glyco_trans_1_4 PF13692.1 OAP56387.1 - 8.6e-25 87.4 0.1 2.8e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_56 PF07429.6 OAP56387.1 - 0.079 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Cation_efflux PF01545.16 OAP56388.1 - 6.4e-52 176.3 8.1 8.7e-52 175.9 3.1 2.0 2 0 0 2 2 2 1 Cation efflux family MFS_3 PF05977.8 OAP56388.1 - 0.015 13.4 0.1 0.026 12.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector NicO PF03824.11 OAP56388.1 - 0.018 14.3 11.9 0.71 9.1 3.5 2.5 2 0 0 2 2 2 0 High-affinity nickel-transport protein SKG6 PF08693.5 OAP56389.1 - 0.0056 15.9 0.3 0.013 14.7 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 OAP56389.1 - 0.0095 15.6 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 Transmembrane protein 51 p450 PF00067.17 OAP56390.1 - 4.3e-55 187.0 0.0 1.2e-54 185.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 YrhK PF14145.1 OAP56390.1 - 0.081 12.6 0.3 0.19 11.4 0.2 1.6 1 0 0 1 1 1 0 YrhK-like protein TFIIIC_delta PF12657.2 OAP56391.1 - 1.4e-29 103.0 0.5 2.7e-29 102.1 0.3 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 OAP56391.1 - 7.7e-21 73.8 0.7 1.6e-20 72.8 0.5 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DUF2321 PF10083.4 OAP56391.1 - 0.05 13.0 0.6 0.12 11.8 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-ribbon_3 PF13248.1 OAP56391.1 - 0.14 11.3 5.7 0.11 11.6 1.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 OAP56391.1 - 0.49 10.2 5.8 0.44 10.4 1.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_3 PF14369.1 OAP56391.1 - 1.5 8.9 5.6 8.7 6.4 0.7 2.7 2 0 0 2 2 2 0 zinc-finger Ank PF00023.25 OAP56393.1 - 1.8e-55 182.1 3.6 9.3e-10 37.8 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 OAP56393.1 - 5.7e-55 183.6 0.2 4.9e-22 78.0 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP56393.1 - 1.8e-35 120.6 3.2 8.3e-13 48.4 0.0 5.7 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP56393.1 - 2.4e-35 116.9 0.2 2.8e-06 27.0 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 OAP56393.1 - 7.1e-27 92.8 3.2 5.4e-07 29.6 0.0 5.8 1 1 3 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 OAP56393.1 - 2.1e-06 27.5 1.9 9.3e-06 25.3 0.2 2.8 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 OAP56393.1 - 2.8e-05 24.2 1.4 0.00022 21.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 OAP56393.1 - 0.0017 18.0 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase HTH_Tnp_4 PF13613.1 OAP56393.1 - 0.0057 16.1 1.0 0.14 11.7 0.4 2.7 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DUF2075 PF09848.4 OAP56393.1 - 0.068 12.1 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mnd1 PF03962.10 OAP56393.1 - 1.3 8.6 4.4 16 5.0 0.0 2.7 3 0 0 3 3 3 0 Mnd1 family Fungal_trans PF04082.13 OAP56395.1 - 7.1e-27 93.9 0.0 2.7e-26 92.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56395.1 - 2e-07 30.7 11.0 4e-07 29.8 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 OAP56396.1 - 1.6e-26 93.1 2.0 4.1e-26 91.8 0.6 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF295 PF03478.13 OAP56396.1 - 0.084 12.2 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF295) COesterase PF00135.23 OAP56397.1 - 6.3e-76 256.1 3.5 1.6e-75 254.8 2.4 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP56397.1 - 2.2e-09 37.1 0.0 6.9e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP56397.1 - 0.0035 17.0 0.1 0.0089 15.7 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_10 PF00331.15 OAP56398.1 - 1.4e-74 250.9 0.0 1.7e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sugar_tr PF00083.19 OAP56399.1 - 2.8e-87 293.1 22.4 3.5e-87 292.8 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56399.1 - 2.3e-28 98.9 23.0 1.3e-27 96.4 13.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP56399.1 - 8.9e-07 27.4 3.6 1.6e-06 26.6 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 OAP56399.1 - 0.0044 15.4 32.5 0.01 14.2 2.9 2.9 2 2 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 OAP56399.1 - 0.011 15.4 8.0 0.29 10.9 0.9 3.1 3 0 0 3 3 3 0 MFS_1 like family Nitroreductase PF00881.19 OAP56399.1 - 0.13 12.0 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Nitroreductase family DEAD PF00270.24 OAP56400.1 - 2.4e-46 157.3 0.0 4e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP56400.1 - 1.1e-26 92.5 0.0 2e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP56400.1 - 0.0015 18.3 0.0 0.014 15.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 OAP56400.1 - 0.0054 16.4 0.2 0.02 14.6 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain Flavi_DEAD PF07652.9 OAP56400.1 - 0.015 15.0 0.0 0.048 13.4 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain AMP-binding PF00501.23 OAP56401.1 - 5.4e-79 265.5 0.0 7.3e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAP56401.1 - 1.4e-61 207.6 0.0 3.3e-61 206.3 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 OAP56401.1 - 1.4e-33 116.1 6.2 5.9e-32 110.8 2.0 3.2 4 0 0 4 4 4 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56401.1 - 3.5e-18 66.2 0.0 6.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP56401.1 - 3.8e-18 65.7 2.1 1.4e-15 57.4 1.5 2.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 OAP56401.1 - 1.8e-16 60.3 0.0 4.5e-09 36.0 0.0 4.0 3 2 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 OAP56401.1 - 4.8e-11 42.7 0.0 1.2e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 OAP56401.1 - 5.7e-09 35.0 0.1 3.3e-06 26.0 0.0 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 OAP56401.1 - 1.9e-07 31.8 1.3 1.7e-06 28.9 0.5 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.12 OAP56401.1 - 1.8e-06 27.0 0.2 0.0013 17.7 0.0 3.0 3 0 0 3 3 3 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 OAP56401.1 - 9.7e-06 25.7 1.1 0.00063 19.7 0.8 3.1 3 0 0 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAP56401.1 - 3e-05 23.0 0.5 0.04 12.8 0.0 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein DFP PF04127.10 OAP56401.1 - 0.026 14.1 0.2 0.18 11.4 0.2 2.2 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 OAP56401.1 - 0.052 13.3 0.7 0.13 12.1 0.5 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cpn60_TCP1 PF00118.19 OAP56402.1 - 1.4e-158 528.5 1.8 1.6e-158 528.3 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Alpha-amylase PF00128.19 OAP56403.1 - 9.4e-97 324.2 0.1 1.5e-96 323.5 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 OAP56403.1 - 0.035 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 OAP56404.1 - 3.7e-72 243.3 20.5 4.2e-72 243.1 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56404.1 - 2.7e-22 78.9 21.9 2.7e-22 78.9 15.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2946 PF11162.3 OAP56405.1 - 2.9 8.1 5.1 3 8.0 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DnaJ PF00226.26 OAP56406.1 - 1.3e-19 69.6 0.9 2.3e-19 68.8 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Aminotran_1_2 PF00155.16 OAP56407.1 - 5.2e-64 216.4 0.0 6.1e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAP56407.1 - 0.016 13.4 0.0 0.031 12.5 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme zf-C2H2_jaz PF12171.3 OAP56409.1 - 5.7e-08 32.6 0.7 1.2e-07 31.6 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP56409.1 - 1.1e-07 31.8 0.7 1.9e-07 31.0 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 OAP56409.1 - 0.0041 16.7 0.2 0.0088 15.6 0.2 1.5 1 0 0 1 1 1 1 DBF zinc finger AKAP95 PF04988.7 OAP56409.1 - 0.2 11.4 0.2 0.2 11.4 0.1 2.1 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Pyridox_oxidase PF01243.15 OAP56410.1 - 3.4e-08 33.3 0.0 5.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.7 OAP56410.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 1 0 1 1 1 0 Putative FMN-binding domain DEAD PF00270.24 OAP56411.1 - 4.1e-44 150.0 0.0 7.9e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP56411.1 - 4.4e-18 64.9 0.1 1.3e-17 63.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP56411.1 - 2.3e-05 24.3 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 OAP56411.1 - 0.034 14.2 0.4 0.16 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 OAP56411.1 - 0.05 13.3 0.4 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain CMS1 PF14617.1 OAP56411.1 - 0.076 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Aldolase_II PF00596.16 OAP56412.1 - 2.7e-48 164.0 0.0 3.5e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TMEM52 PF14979.1 OAP56412.1 - 0.024 14.5 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Transmembrane 52 SGL PF08450.7 OAP56413.1 - 3.5e-08 33.1 0.1 5.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 OAP56413.1 - 0.021 14.7 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Arylesterase DUF581 PF04570.9 OAP56414.1 - 0.019 14.2 2.8 0.35 10.1 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF581) BIR PF00653.16 OAP56415.1 - 4.7e-43 145.4 2.3 1.8e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain PAT1 PF09770.4 OAP56415.1 - 0.61 8.2 23.1 0.83 7.8 16.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mmp37 PF09139.6 OAP56416.1 - 1.3e-134 448.4 0.0 1.6e-134 448.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 MAPEG PF01124.13 OAP56417.1 - 1.8e-12 46.9 5.0 2.5e-12 46.5 3.5 1.3 1 1 0 1 1 1 1 MAPEG family NAD_binding_2 PF03446.10 OAP56420.1 - 1.3e-29 103.1 0.0 2.9e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP56420.1 - 1.1e-23 83.5 0.2 2.8e-20 72.6 0.0 2.8 3 0 0 3 3 3 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 OAP56420.1 - 9.3e-07 29.2 0.1 3.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAP56420.1 - 0.00071 19.2 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 OAP56420.1 - 0.0061 15.9 0.0 0.11 11.9 0.0 2.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2681 PF10883.3 OAP56422.1 - 0.0048 17.0 5.7 0.0048 17.0 4.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) Adeno_PX PF05829.7 OAP56422.1 - 0.45 10.0 4.3 0.1 12.0 0.3 1.9 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) RabGAP-TBC PF00566.13 OAP56423.1 - 4.2e-32 111.3 0.0 6.5e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sas10_Utp3 PF04000.10 OAP56424.1 - 1.9e-15 56.7 0.1 3.9e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DMAP_binding PF06464.6 OAP56424.1 - 2 9.0 9.4 0.94 10.0 1.6 2.6 2 0 0 2 2 2 0 DMAP1-binding Domain Tautomerase_3 PF14832.1 OAP56425.1 - 1.1e-46 158.1 0.1 1.3e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 OAP56425.1 - 2e-05 24.1 0.0 9.6e-05 21.9 0.0 2.0 1 1 1 2 2 2 1 Tautomerase enzyme Peptidase_C13 PF01650.13 OAP56426.1 - 3.5e-40 137.9 0.0 4.8e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.17 OAP56426.1 - 0.07 12.8 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Caspase domain DUF4023 PF13215.1 OAP56427.1 - 0.0011 18.6 0.2 0.0011 18.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4023) TFIID_20kDa PF03847.8 OAP56427.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A F-box-like PF12937.2 OAP56427.1 - 0.018 14.7 4.4 0.044 13.5 0.1 2.7 3 0 0 3 3 3 0 F-box-like Fasciclin PF02469.17 OAP56428.1 - 1.5e-24 86.3 0.0 1.4e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain SKG6 PF08693.5 OAP56428.1 - 0.013 14.8 0.2 0.033 13.5 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Polysacc_deac_1 PF01522.16 OAP56429.1 - 1.8e-19 69.5 0.0 5.6e-19 67.9 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase CDC45 PF02724.9 OAP56430.1 - 1.5e-219 730.1 13.6 6e-218 724.8 9.4 3.0 1 1 0 1 1 1 1 CDC45-like protein DUF1777 PF08648.7 OAP56430.1 - 0.17 11.6 37.6 0.018 14.7 7.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) SDA1 PF05285.7 OAP56430.1 - 0.6 9.3 33.4 0.98 8.6 10.4 2.2 2 0 0 2 2 2 0 SDA1 Tom22 PF04281.8 OAP56430.1 - 1.3 8.5 0.0 1.3 8.5 0.0 3.6 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 TFIIF_alpha PF05793.7 OAP56430.1 - 2.9 6.1 34.1 1.9 6.7 12.1 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 OAP56430.1 - 2.9 6.2 38.3 0.014 13.9 2.6 2.2 2 0 0 2 2 2 0 Daxx Family DUF1510 PF07423.6 OAP56430.1 - 4.2 6.6 32.2 0.39 10.0 10.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Lipase_GDSL_2 PF13472.1 OAP56431.1 - 2.5e-16 60.3 0.3 4.5e-16 59.4 0.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DHH PF01368.15 OAP56432.1 - 2.4e-08 33.7 0.0 3.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 DHH family p450 PF00067.17 OAP56433.1 - 5.3e-66 223.0 0.0 6.6e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med4 PF10018.4 OAP56434.1 - 8.8e-21 74.1 6.9 3.4e-20 72.2 4.8 2.1 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Lzipper-MIP1 PF14389.1 OAP56434.1 - 0.27 11.3 3.1 2.2 8.4 0.1 3.0 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 MFS_1 PF07690.11 OAP56436.1 - 3.2e-23 82.0 15.9 3.2e-23 82.0 11.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP56436.1 - 4.7e-07 28.3 3.4 9.5e-07 27.3 2.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RabGAP-TBC PF00566.13 OAP56437.1 - 1.9e-48 164.7 0.0 4e-48 163.7 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CAF-1_p150 PF11600.3 OAP56437.1 - 0.0043 16.4 7.4 0.0043 16.4 5.2 3.7 3 1 1 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2422 PF10337.4 OAP56437.1 - 0.9 8.2 3.5 23 3.5 2.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) Occludin_ELL PF07303.8 OAP56437.1 - 2.7 8.7 12.7 2.7 8.7 2.4 2.7 2 0 0 2 2 2 0 Occludin homology domain DUF3584 PF12128.3 OAP56437.1 - 3.3 4.9 26.2 5.1 4.2 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DNA_topoisoIV PF00521.15 OAP56438.1 - 1e-135 452.8 0.0 1e-135 452.8 0.0 2.1 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 OAP56438.1 - 2.5e-37 127.7 6.8 7.2e-37 126.2 4.7 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 OAP56438.1 - 1.3e-13 50.7 0.0 8.1e-13 48.2 0.0 2.5 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 OAP56438.1 - 6.5e-11 41.9 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAP56438.1 - 3.2e-05 23.5 1.7 9.9e-05 22.0 1.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NusA_N PF08529.6 OAP56438.1 - 0.018 15.0 0.1 0.018 15.0 0.1 3.4 3 0 0 3 3 3 0 NusA N-terminal domain DUF2305 PF10230.4 OAP56438.1 - 0.018 14.4 0.8 0.077 12.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) zf-CCCH PF00642.19 OAP56440.1 - 6.9 6.4 10.4 5.8 6.7 1.4 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PLA2G12 PF06951.6 OAP56442.1 - 8.4e-09 35.3 7.9 1.3e-08 34.7 5.5 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) F-box PF00646.28 OAP56443.1 - 7.2e-05 22.3 0.3 0.00014 21.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP56443.1 - 0.67 9.7 5.3 0.37 10.5 0.4 2.8 3 0 0 3 3 3 0 F-box-like MFS_1 PF07690.11 OAP56444.1 - 4.3e-28 98.0 29.8 4.3e-28 98.0 20.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily PsbY PF06298.6 OAP56444.1 - 0.073 12.6 0.6 0.22 11.0 0.4 1.8 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) FAA_hydrolase PF01557.13 OAP56445.1 - 1.5e-58 197.8 0.0 1.9e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.14 OAP56446.1 - 1.3e-23 83.6 0.2 2.3e-15 56.5 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAP56446.1 - 0.00027 20.9 0.0 0.00061 19.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP56446.1 - 0.0083 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 OAP56446.1 - 0.013 14.3 0.0 0.52 9.0 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.1 OAP56446.1 - 0.031 14.3 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP56446.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP56446.1 - 0.6 10.5 0.0 0.6 10.5 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 OAP56447.1 - 5.6e-54 183.3 0.0 7.2e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 OAP56448.1 - 8e-11 41.2 0.3 1.2e-10 40.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56448.1 - 3.6e-08 33.1 10.0 7.9e-08 32.0 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 OAP56449.1 - 7.2e-19 68.0 0.0 7.9e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP56449.1 - 3.5e-08 32.7 4.3 0.00012 21.0 0.4 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP56449.1 - 2.3e-07 29.6 0.1 0.002 16.6 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 OAP56449.1 - 1.1e-06 27.8 0.1 1.2e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP56449.1 - 2e-06 27.8 0.0 1e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP56449.1 - 7.1e-06 25.9 0.2 1.6e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP56449.1 - 7.1e-06 26.2 0.2 7.4e-05 22.9 0.2 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP56449.1 - 4e-05 22.8 0.0 7.2e-05 22.0 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP56449.1 - 0.00011 21.2 0.3 1.8 7.4 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.17 OAP56449.1 - 0.00021 20.2 0.9 0.0024 16.8 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 OAP56449.1 - 0.00039 20.7 0.2 0.11 12.9 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP56449.1 - 0.0072 15.4 0.3 2.7 6.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 OAP56449.1 - 0.011 15.5 0.1 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 OAP56449.1 - 0.027 13.5 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 OAP56449.1 - 0.043 12.4 0.2 5.5 5.5 0.1 2.4 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 OAP56449.1 - 0.16 11.6 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPP_enzyme_N PF02776.13 OAP56450.1 - 6.3e-35 120.1 0.0 1.1e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP56450.1 - 4.1e-19 68.7 0.0 1.3e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 OAP56450.1 - 9.2e-12 44.7 1.3 2.5e-11 43.3 0.1 2.2 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyoxalase PF00903.20 OAP56451.1 - 6.2e-14 52.0 0.1 8.5e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP56451.1 - 1.6e-10 41.5 0.0 2.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 OAP56451.1 - 0.03 14.3 0.0 0.055 13.4 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MMR_HSR1 PF01926.18 OAP56452.1 - 5.3e-10 39.2 0.0 1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 OAP56452.1 - 1.4e-07 30.8 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 OAP56452.1 - 0.00011 21.4 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Guanylate_kin PF00625.16 OAP56452.1 - 0.0033 16.9 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase FeoB_N PF02421.13 OAP56452.1 - 0.009 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 OAP56452.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 OAP56452.1 - 0.027 14.9 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 OAP56452.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 OAP56452.1 - 0.042 13.3 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 OAP56452.1 - 0.18 11.6 0.1 5.6 6.7 0.1 2.3 1 1 1 2 2 2 0 Dynamin family TPR_2 PF07719.12 OAP56455.1 - 0.014 15.2 0.2 0.041 13.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PCI PF01399.22 OAP56455.1 - 0.019 15.2 0.1 6.7 7.0 0.0 2.9 3 0 0 3 3 3 0 PCI domain TPR_14 PF13428.1 OAP56455.1 - 0.022 15.3 0.1 0.21 12.3 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP56455.1 - 0.029 14.2 0.7 0.072 13.0 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAP56455.1 - 0.11 12.8 0.1 0.95 9.8 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 OAP56455.1 - 2.1 8.5 7.4 0.73 10.0 2.4 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.27 OAP56456.1 - 2.5e-39 131.7 7.7 2.3e-08 33.5 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 OAP56456.1 - 1.4e-30 105.1 12.7 2.4e-30 104.4 8.8 1.4 1 0 0 1 1 1 1 Sof1-like domain DUF3022 PF11226.3 OAP56456.1 - 0.026 14.3 0.2 0.059 13.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) PCI PF01399.22 OAP56457.1 - 2.2e-20 72.9 0.8 6.3e-20 71.4 0.2 2.1 2 0 0 2 2 2 1 PCI domain DDRGK PF09756.4 OAP56457.1 - 0.0002 20.8 0.4 0.00042 19.7 0.3 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_8 PF13181.1 OAP56457.1 - 0.0048 16.5 4.1 14 5.7 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP56457.1 - 0.0062 16.2 3.8 4 7.4 0.1 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 OAP56457.1 - 0.012 15.3 0.7 0.031 14.0 0.5 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 HTH_Crp_2 PF13545.1 OAP56457.1 - 0.013 15.2 0.1 5.5 6.8 0.0 3.0 2 1 1 3 3 3 0 Crp-like helix-turn-helix domain DUF4456 PF14644.1 OAP56457.1 - 0.026 13.7 3.2 0.37 9.9 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) TPPII_N PF12583.3 OAP56457.1 - 0.04 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Med2 PF11214.3 OAP56457.1 - 0.31 11.0 2.8 0.4 10.7 0.1 2.6 3 1 0 3 3 3 0 Mediator complex subunit 2 TPR_6 PF13174.1 OAP56457.1 - 2 9.0 12.4 2.4 8.8 0.0 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP56457.1 - 2.7 7.7 6.2 26 4.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP56457.1 - 5.6 7.7 14.9 4.5 8.0 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat EF-hand_7 PF13499.1 OAP56458.1 - 4.7e-30 103.5 10.1 1.7e-13 50.4 0.2 3.2 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 OAP56458.1 - 8e-25 84.2 12.0 3.8e-08 32.0 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 OAP56458.1 - 5.5e-24 81.8 3.8 2.6e-06 26.8 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 OAP56458.1 - 2.4e-17 61.3 12.9 2.6e-05 23.3 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 OAP56458.1 - 1e-14 53.8 14.1 6.1e-06 25.7 0.7 4.2 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 OAP56458.1 - 1.4e-08 34.4 5.9 0.0018 17.9 0.1 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 OAP56458.1 - 0.00024 20.9 0.9 0.0097 15.8 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 OAP56458.1 - 0.00059 19.4 2.1 1 9.0 0.0 3.9 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 OAP56458.1 - 0.0011 18.9 1.4 0.65 10.0 0.1 3.0 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 OAP56458.1 - 0.019 13.5 0.5 1.6 7.2 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.6 OAP56458.1 - 0.03 14.3 0.1 5 7.2 0.0 3.1 3 1 0 3 3 3 0 EF hand Mad3_BUB1_II PF08171.6 OAP56458.1 - 0.087 12.7 0.0 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 DAG_kinase_N PF14513.1 OAP56458.1 - 0.76 9.9 4.1 1 9.5 2.8 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus EMP70 PF02990.11 OAP56459.1 - 4.5e-185 616.0 0.0 5.5e-185 615.7 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 HATPase_c PF02518.21 OAP56460.1 - 1.3e-24 86.0 0.2 3.9e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP56460.1 - 4.2e-20 71.8 0.0 1.2e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 OAP56460.1 - 3.1e-17 62.3 0.0 7.6e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 OAP56460.1 - 3.1e-09 36.7 1.1 0.00071 19.6 0.0 4.0 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.1 OAP56460.1 - 1.4e-06 28.6 0.0 0.00067 19.9 0.0 3.0 2 1 0 2 2 2 1 PAS domain PAS_4 PF08448.5 OAP56460.1 - 0.0021 18.0 0.0 0.061 13.3 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 OAP56460.1 - 0.13 12.0 0.0 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 PAS fold KxDL PF10241.4 OAP56461.1 - 1.7e-28 98.3 2.8 2.3e-28 97.9 1.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein TPR_MLP1_2 PF07926.7 OAP56461.1 - 0.66 9.7 9.2 9.8 5.9 6.5 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 OAP56461.1 - 6.5 6.6 10.7 8.4 6.2 2.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding GMC_oxred_N PF00732.14 OAP56463.1 - 2.1e-47 161.7 0.0 6.4e-47 160.1 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP56463.1 - 1.6e-34 119.2 0.1 2.4e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP56463.1 - 2.4e-06 26.7 1.4 0.025 13.4 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP56463.1 - 4.3e-05 23.4 0.5 0.00044 20.2 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP56463.1 - 0.00083 18.3 0.0 0.0018 17.2 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP56464.1 - 2.3e-18 67.0 0.0 8.4e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP56464.1 - 1.4e-09 36.6 0.1 6.9e-09 34.4 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP56464.1 - 6.1e-06 26.1 0.0 1.8e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP56464.1 - 8e-05 21.7 0.4 0.04 12.8 0.0 2.9 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 OAP56464.1 - 0.00017 21.7 1.4 0.41 10.7 0.0 3.3 4 0 0 4 4 4 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 OAP56464.1 - 0.0014 17.6 0.9 0.081 11.8 0.8 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP56464.1 - 0.0022 16.9 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 OAP56464.1 - 0.012 14.7 0.3 0.022 13.8 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 OAP56464.1 - 0.095 12.4 0.0 1.5 8.5 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 OAP56464.1 - 0.097 11.8 0.7 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 OAP56464.1 - 0.15 10.9 0.1 0.99 8.2 0.0 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 OAP56464.1 - 1.6 8.5 5.5 2 8.2 0.6 2.9 3 0 0 3 3 3 0 ThiF family DSPc PF00782.15 OAP56465.1 - 1.2e-18 66.9 0.0 3.6e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAP56465.1 - 0.00095 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase COesterase PF00135.23 OAP56466.1 - 2.7e-42 145.2 0.2 4.2e-36 124.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP56466.1 - 0.034 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TFR_dimer PF04253.10 OAP56467.1 - 1.9e-24 85.5 0.0 3.2e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 OAP56467.1 - 1e-14 54.7 0.0 2.5e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 OAP56467.1 - 1.3e-07 31.2 0.1 3.3e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 PA domain PRP3 PF08572.5 OAP56468.1 - 6.7e-70 234.9 2.8 1.1e-69 234.2 1.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 OAP56468.1 - 1.8e-35 121.3 0.6 1.8e-35 121.3 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF3138 PF11336.3 OAP56468.1 - 2.6 6.1 8.0 4.6 5.2 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) adh_short PF00106.20 OAP56469.1 - 5.4e-10 39.4 0.5 3.4e-09 36.8 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56469.1 - 8.6e-08 32.2 0.0 0.0026 17.5 0.0 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP56469.1 - 0.0082 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Trehalose_PPase PF02358.11 OAP56469.1 - 0.043 12.7 0.0 0.23 10.3 0.0 1.9 2 0 0 2 2 2 0 Trehalose-phosphatase KR PF08659.5 OAP56469.1 - 0.051 13.2 0.1 0.91 9.1 0.0 2.1 1 1 0 1 1 1 0 KR domain GST_N PF02798.15 OAP56470.1 - 5.5e-13 48.8 0.0 1.3e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAP56470.1 - 7.8e-13 48.4 0.3 2.9e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP56470.1 - 6.2e-12 45.3 0.2 1.8e-11 43.8 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP56470.1 - 6.6e-12 45.2 0.1 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP56470.1 - 0.00022 21.6 0.2 0.00033 21.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAP56470.1 - 0.021 14.7 1.5 0.064 13.1 0.0 2.3 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 OAP56470.1 - 0.057 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain COX2 PF00116.15 OAP56470.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain Sugar_tr PF00083.19 OAP56471.1 - 3.4e-81 273.1 20.9 4.1e-81 272.8 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56471.1 - 1.2e-25 89.9 44.5 2.2e-22 79.2 15.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP56471.1 - 0.00076 17.8 4.2 0.00076 17.8 2.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 OAP56471.1 - 0.00092 18.9 0.3 0.62 9.8 0.0 2.9 2 1 0 2 2 2 2 MFS_1 like family PUCC PF03209.10 OAP56471.1 - 0.0054 15.4 14.3 0.0054 15.4 9.9 1.7 2 0 0 2 2 2 1 PUCC protein p450 PF00067.17 OAP56472.1 - 1.6e-66 224.7 0.0 2.1e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 OAP56473.1 - 3.1e-28 98.7 0.7 4.2e-28 98.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP56473.1 - 9e-10 38.5 0.2 1.3e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP56473.1 - 2.7e-08 33.8 0.0 2.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP56473.1 - 0.00041 19.8 1.8 0.0093 15.4 1.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP56473.1 - 0.001 17.8 0.1 0.0013 17.4 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.5 OAP56473.1 - 0.0019 17.3 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 OAP56473.1 - 0.0066 15.3 0.0 0.009 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CmcI PF04989.7 OAP56473.1 - 0.084 12.1 0.2 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase NAD_binding_10 PF13460.1 OAP56473.1 - 0.16 11.9 0.9 0.26 11.2 0.6 1.4 1 0 0 1 1 1 0 NADH(P)-binding Fungal_trans PF04082.13 OAP56474.1 - 1.3e-18 66.8 0.1 2.3e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MEDS PF14417.1 OAP56474.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain adh_short_C2 PF13561.1 OAP56475.1 - 6.3e-24 85.0 0.0 6.9e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP56475.1 - 1.9e-10 40.8 0.0 2.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP56475.1 - 0.019 14.6 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.11 OAP56476.1 - 2.1e-35 122.1 19.7 2.1e-35 122.1 13.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP56476.1 - 5.1e-14 51.6 1.9 5.1e-14 51.6 1.3 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Pyr_redox_3 PF13738.1 OAP56477.1 - 1.5e-13 51.3 0.0 4e-11 43.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP56477.1 - 5.8e-10 37.9 0.7 6.6e-06 24.5 0.0 3.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP56477.1 - 2.8e-07 30.4 0.0 8.3e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP56477.1 - 2.8e-05 23.9 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAP56477.1 - 9.9e-05 21.3 0.0 0.013 14.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP56477.1 - 0.0028 17.5 0.0 2.3 8.0 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 OAP56477.1 - 0.011 14.1 0.1 0.015 13.6 0.0 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family DUF498 PF04430.9 OAP56477.1 - 0.013 15.0 0.0 0.51 9.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) NAD_binding_7 PF13241.1 OAP56477.1 - 0.017 15.3 0.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding CoA_transf_3 PF02515.12 OAP56478.1 - 1.2e-34 119.2 0.0 7.2e-31 106.9 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III DLH PF01738.13 OAP56478.1 - 3.4e-22 78.8 0.0 6.2e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP56478.1 - 8.8e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chorein_N PF12624.2 OAP56478.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of Chorein, a TM vesicle-mediated sorter PQ-loop PF04193.9 OAP56479.1 - 0.0038 16.7 0.2 0.0038 16.7 0.1 2.1 2 0 0 2 2 2 1 PQ loop repeat MARVEL PF01284.18 OAP56479.1 - 0.0084 15.9 18.9 0.16 11.7 13.1 2.0 1 1 0 1 1 1 1 Membrane-associating domain DUF962 PF06127.6 OAP56479.1 - 0.23 11.3 1.6 0.38 10.6 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF962) RNA_pol_Rpb1_5 PF04998.12 OAP56480.1 - 2.3e-87 292.7 0.0 1.3e-86 290.2 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 OAP56480.1 - 1.1e-63 214.0 0.2 2.8e-63 212.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 OAP56480.1 - 1.5e-36 125.5 0.1 1.1e-34 119.4 0.0 3.5 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 OAP56480.1 - 6.5e-25 88.1 4.3 5.8e-15 55.3 0.1 3.2 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 OAP56480.1 - 2.6e-18 65.7 0.0 1.1e-17 63.7 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 adh_short PF00106.20 OAP56482.1 - 1.6e-15 57.4 0.1 2.7e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56482.1 - 2.3e-07 30.8 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP56482.1 - 0.00027 20.6 0.0 0.00072 19.2 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP56482.1 - 0.12 11.7 0.0 3 7.2 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 OAP56483.1 - 1.1e-85 287.9 21.6 1.2e-85 287.7 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56483.1 - 1.5e-26 92.9 42.5 3.8e-20 71.9 13.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 OAP56484.1 - 0.23 11.2 3.4 2.6 7.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) GFO_IDH_MocA PF01408.17 OAP56485.1 - 4.3e-10 40.1 0.0 2.2e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP56485.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PrpF PF04303.8 OAP56486.1 - 1.1e-85 287.6 0.0 1.4e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 PrpF protein DLH PF01738.13 OAP56487.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP56487.1 - 6.2e-06 26.0 0.0 8.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAP56487.1 - 5.6e-05 22.8 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP56487.1 - 0.015 14.5 0.0 0.034 13.3 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ammonium_transp PF00909.16 OAP56488.1 - 1e-76 257.9 31.9 1.2e-76 257.8 22.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2614 PF11023.3 OAP56488.1 - 1.6 8.5 5.1 0.39 10.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) zf-PARP PF00645.13 OAP56489.1 - 8.3e-20 70.8 0.1 2.1e-19 69.5 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Lactamase_B_2 PF12706.2 OAP56490.1 - 5e-41 140.3 0.1 6.5e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP56490.1 - 2.5e-10 40.3 0.0 1.5e-09 37.8 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAP56490.1 - 2e-05 24.3 0.1 0.00099 18.8 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily BCS1_N PF08740.6 OAP56491.1 - 2e-48 164.4 0.1 2.8e-48 164.0 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 OAP56491.1 - 3.8e-19 69.2 0.0 6.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAP56491.1 - 1.3e-05 26.0 0.0 3.3e-05 24.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 OAP56491.1 - 6.7e-05 22.9 0.0 0.00042 20.3 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.1 OAP56491.1 - 0.00016 21.1 0.0 0.00039 19.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAP56491.1 - 0.00057 19.6 0.0 0.0015 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 OAP56491.1 - 0.0014 17.5 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 OAP56491.1 - 0.0056 16.9 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAP56491.1 - 0.0066 16.5 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAP56491.1 - 0.0091 15.8 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 OAP56491.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAP56491.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 OAP56491.1 - 0.013 15.2 0.0 0.075 12.7 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 OAP56491.1 - 0.024 14.2 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 OAP56491.1 - 0.028 14.7 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PPV_E1_C PF00519.12 OAP56491.1 - 0.029 12.9 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_29 PF13555.1 OAP56491.1 - 0.03 13.8 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 OAP56491.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 OAP56491.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 OAP56491.1 - 0.092 11.9 0.0 0.39 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 OAP56491.1 - 0.17 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_11 PF13086.1 OAP56491.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 OAP56492.1 - 2.3e-15 56.6 0.0 9.2e-14 51.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP56492.1 - 1.1e-12 48.0 0.5 1.1e-09 38.5 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 OAP56492.1 - 1.2e-12 46.9 0.0 7.6e-07 28.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 OAP56492.1 - 8.5e-12 44.9 1.9 5.1e-08 32.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP56492.1 - 9.9e-11 40.8 0.0 0.00041 20.3 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeat NACHT PF05729.7 OAP56492.1 - 2.6e-06 27.1 0.0 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 OAP56492.1 - 0.00021 21.3 0.1 0.0018 18.2 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP56492.1 - 0.016 15.3 0.0 0.074 13.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAP56492.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Dsl1_C PF11989.3 OAP56492.1 - 0.071 12.2 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal FtsK_SpoIIIE PF01580.13 OAP56492.1 - 0.085 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Nol1_Nop2_Fmu PF01189.12 OAP56493.1 - 1.8e-30 106.3 0.0 1.2e-17 64.2 0.0 4.4 4 1 1 5 5 5 4 NOL1/NOP2/sun family FtsJ PF01728.14 OAP56493.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 OAP56493.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_3 PF00933.16 OAP56495.1 - 6.7e-79 264.9 0.0 1.1e-78 264.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAP56495.1 - 1.5e-63 214.4 0.0 5.5e-63 212.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 OAP56495.1 - 9.7e-24 83.1 0.2 2.2e-23 81.9 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 OAP56495.1 - 1.3e-12 47.5 0.0 2.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Zn_clus PF00172.13 OAP56496.1 - 0.00067 19.5 10.8 0.0016 18.2 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP56497.1 - 2.8e-26 92.0 28.8 4.1e-26 91.5 18.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Tetraspannin PF00335.15 OAP56497.1 - 6.4 5.9 8.7 2.1e+02 1.0 6.0 2.7 1 1 0 1 1 1 0 Tetraspanin family Abhydrolase_3 PF07859.8 OAP56498.1 - 5e-15 55.6 0.0 1.5e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP56498.1 - 3e-08 33.5 0.0 4.9e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP56498.1 - 7.9e-07 28.5 0.0 0.0018 17.5 0.0 3.0 3 0 0 3 3 3 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 OAP56498.1 - 1.8e-06 27.0 0.0 2.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.23 OAP56498.1 - 0.0017 17.1 0.1 0.0017 17.1 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family DOMON PF03351.12 OAP56499.1 - 3.1e-07 30.3 0.3 5.8e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 OAP56499.1 - 4.8e-07 29.6 14.1 4.8e-07 29.6 9.8 2.2 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 DUF2453 PF10507.4 OAP56499.1 - 0.075 12.8 3.3 0.081 12.7 0.0 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2453) DUF4457 PF14652.1 OAP56499.1 - 0.087 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DUF2427 PF10348.4 OAP56499.1 - 0.5 9.9 15.5 0.021 14.3 5.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) DUF389 PF04087.9 OAP56499.1 - 5 7.0 11.6 0.49 10.3 3.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF389) Rab5ip PF07019.7 OAP56500.1 - 0.077 13.1 1.1 0.23 11.6 0.2 2.2 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) NAD_binding_10 PF13460.1 OAP56501.1 - 7.4e-07 29.3 0.0 9.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP56501.1 - 0.0076 15.2 0.0 0.071 12.0 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 OAP56501.1 - 0.025 13.2 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 OAP56501.1 - 0.13 12.5 0.0 0.47 10.7 0.0 1.8 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 OAP56501.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RNA_pol_Rpb5_C PF01191.14 OAP56502.1 - 1.5e-30 104.5 0.1 2.7e-30 103.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 OAP56502.1 - 1e-26 93.1 0.0 1.7e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 OAP56502.1 - 0.0033 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease adh_short PF00106.20 OAP56505.1 - 1.3e-20 73.9 0.2 1.9e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56505.1 - 2.5e-11 43.8 0.0 3.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP56505.1 - 7.1e-06 25.7 0.2 1.1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAP56505.1 - 0.048 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGM_PMM_II PF02879.11 OAP56507.1 - 5.1e-18 65.3 0.3 3.1e-16 59.5 0.0 3.3 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 OAP56507.1 - 2.8e-17 62.4 1.1 3.9e-09 36.1 0.0 2.9 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 OAP56507.1 - 5.1e-10 39.2 0.3 1.3e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 OAP56507.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Per1 PF04080.8 OAP56508.1 - 5.6e-111 370.2 10.7 6.9e-111 369.9 7.4 1.1 1 0 0 1 1 1 1 Per1-like DIL PF01843.14 OAP56509.1 - 2.8e-19 68.9 3.6 9.5e-18 64.0 0.8 2.9 2 1 0 2 2 2 1 DIL domain Ank_2 PF12796.2 OAP56509.1 - 1.5e-18 66.9 0.3 5.9e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAP56509.1 - 1.2e-15 56.3 0.4 3e-07 29.9 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAP56509.1 - 1.9e-12 47.0 0.2 9.1e-08 32.1 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP56509.1 - 6.9e-12 45.5 1.3 2.5e-06 27.8 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP56509.1 - 9.8e-09 34.6 1.0 0.00044 20.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Shisa PF13908.1 OAP56510.1 - 0.003 17.7 0.0 0.003 17.7 0.0 2.6 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator SKG6 PF08693.5 OAP56510.1 - 0.027 13.7 1.1 0.076 12.3 0.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 OAP56510.1 - 0.097 12.2 2.1 0.081 12.5 0.3 1.7 2 0 0 2 2 2 0 Rifin/stevor family DUF1180 PF06679.7 OAP56510.1 - 0.92 9.3 12.5 0.084 12.7 2.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) YopD PF05844.7 OAP56510.1 - 2.5 7.0 8.8 0.15 11.0 1.0 2.1 1 1 1 2 2 2 0 YopD protein UCH PF00443.24 OAP56511.1 - 6e-23 81.3 0.0 1.3e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nucleoplasmin PF03066.10 OAP56511.1 - 0.68 9.4 20.8 6.2 6.3 10.9 2.7 2 0 0 2 2 2 0 Nucleoplasmin GGDN PF05165.7 OAP56512.1 - 0.019 14.0 0.6 0.027 13.5 0.4 1.3 1 0 0 1 1 1 0 GGDN family AAA PF00004.24 OAP56513.1 - 3.1e-51 173.0 0.0 5.7e-38 130.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 OAP56513.1 - 5.8e-11 42.1 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_14 PF13173.1 OAP56513.1 - 3.2e-10 39.9 0.0 4e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 OAP56513.1 - 2.2e-09 36.8 0.3 3.2e-08 33.0 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 OAP56513.1 - 2.8e-09 37.1 0.2 0.00036 20.6 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAP56513.1 - 2.8e-09 37.2 0.0 0.0014 18.6 0.0 2.9 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 OAP56513.1 - 6.7e-09 35.5 0.0 0.0015 18.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 OAP56513.1 - 7.9e-09 36.3 0.0 0.0025 18.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 OAP56513.1 - 4.5e-08 33.2 0.0 0.0085 16.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 OAP56513.1 - 6.9e-08 32.1 1.6 0.022 14.5 0.1 3.4 3 0 0 3 3 3 2 Part of AAA domain AAA_18 PF13238.1 OAP56513.1 - 1.7e-07 31.5 0.2 0.0047 17.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.7 OAP56513.1 - 2.9e-07 29.8 0.0 0.02 13.9 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 OAP56513.1 - 3.3e-07 30.2 0.0 0.0098 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 OAP56513.1 - 3.7e-07 29.2 0.3 0.1 11.4 0.0 3.9 2 1 1 4 4 4 2 NB-ARC domain Mg_chelatase PF01078.16 OAP56513.1 - 9.4e-07 28.2 0.1 0.0048 16.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 OAP56513.1 - 1.2e-06 28.3 1.4 0.016 14.8 0.0 3.6 4 0 0 4 4 3 1 NACHT domain IstB_IS21 PF01695.12 OAP56513.1 - 2.5e-06 27.0 0.2 0.04 13.3 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein TIP49 PF06068.8 OAP56513.1 - 2.9e-06 26.2 0.0 0.012 14.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_2 PF07724.9 OAP56513.1 - 3.4e-06 27.0 0.0 3.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 OAP56513.1 - 9.5e-06 25.6 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAP56513.1 - 1.4e-05 24.5 0.1 0.33 10.3 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_24 PF13479.1 OAP56513.1 - 3.3e-05 23.5 0.2 0.12 11.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 OAP56513.1 - 8.2e-05 22.9 0.3 0.038 14.2 0.1 2.7 3 0 0 3 3 2 1 ABC transporter PhoH PF02562.11 OAP56513.1 - 0.00011 21.4 0.0 0.21 10.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Zeta_toxin PF06414.7 OAP56513.1 - 0.00012 21.3 0.0 0.5 9.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin KaiC PF06745.8 OAP56513.1 - 0.00027 20.1 0.2 0.031 13.4 0.1 2.6 2 1 0 2 2 2 1 KaiC Arch_ATPase PF01637.13 OAP56513.1 - 0.00052 19.7 0.7 4.1 7.0 0.2 3.4 2 2 1 3 3 3 0 Archaeal ATPase Parvo_NS1 PF01057.12 OAP56513.1 - 0.00094 18.1 0.0 0.4 9.5 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 OAP56513.1 - 0.0032 16.9 0.0 0.58 9.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.1 OAP56513.1 - 0.0048 16.5 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 OAP56513.1 - 0.0053 15.7 0.0 0.32 9.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 OAP56513.1 - 0.0095 15.7 0.1 2.6 7.8 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UPF0079 PF02367.12 OAP56513.1 - 0.01 15.4 0.1 0.99 9.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 OAP56513.1 - 0.013 15.1 0.0 0.9 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 OAP56513.1 - 0.013 15.0 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 OAP56513.1 - 0.013 15.0 0.0 0.39 10.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 OAP56513.1 - 0.017 14.6 0.0 5.6 6.3 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KTI12 PF08433.5 OAP56513.1 - 0.06 12.5 0.0 0.56 9.3 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 OAP56513.1 - 0.077 12.7 0.1 18 4.9 0.0 2.8 3 0 0 3 3 2 0 NTPase KAP_NTPase PF07693.9 OAP56513.1 - 0.091 11.7 0.0 2.1 7.2 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.1 OAP56513.1 - 0.094 12.7 0.0 8.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.10 OAP56513.1 - 0.24 10.0 0.0 14 4.2 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Glyoxalase_2 PF12681.2 OAP56514.1 - 9.6e-13 48.6 0.1 8.3e-12 45.6 0.1 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP56514.1 - 3.7e-12 46.3 0.0 2.6e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 OAP56514.1 - 0.00016 21.6 0.0 0.00048 20.0 0.0 1.9 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hydro_67M PF07488.7 OAP56515.1 - 6.9e-147 488.5 0.1 9.8e-147 488.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 OAP56515.1 - 9.4e-94 313.0 4.1 1.4e-93 312.4 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 OAP56515.1 - 2.2e-24 85.8 0.0 4.3e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 OAP56515.1 - 0.0011 19.5 0.1 0.0043 17.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 MFS_1 PF07690.11 OAP56517.1 - 3.3e-36 124.7 24.4 9.9e-36 123.1 16.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAP56517.1 - 9.6e-05 20.9 9.4 0.00043 18.8 4.3 2.9 1 1 1 2 2 2 1 MFS/sugar transport protein DUF3589 PF12141.3 OAP56518.1 - 1.1e-85 287.8 0.0 1.9e-85 287.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) Sugar_tr PF00083.19 OAP56518.1 - 2.6e-75 253.7 20.9 3.6e-75 253.2 14.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56518.1 - 6.4e-11 41.5 48.8 1.7e-10 40.1 17.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MaoC_dehydratas PF01575.14 OAP56519.1 - 1e-23 83.0 0.0 1.9e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAP56519.1 - 8e-07 28.9 0.0 8.9e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Methyltransf_31 PF13847.1 OAP56520.1 - 2.7e-12 46.5 0.0 4.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 OAP56520.1 - 1.4e-10 40.6 0.0 1.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 OAP56520.1 - 2.1e-10 40.2 0.1 3.2e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 OAP56520.1 - 3.9e-09 37.0 0.0 8.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP56520.1 - 2.4e-08 34.0 0.0 5.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP56520.1 - 1.6e-07 31.6 0.0 4.8e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP56520.1 - 2.9e-07 30.3 0.0 3.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 OAP56520.1 - 7.6e-06 24.8 0.1 1.2e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 OAP56520.1 - 3.7e-05 23.1 0.1 6.4e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 OAP56520.1 - 6.4e-05 23.2 0.0 0.00016 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP56520.1 - 8.9e-05 22.8 0.0 0.0002 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAP56520.1 - 0.00022 21.2 0.0 0.00051 20.0 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.15 OAP56520.1 - 0.001 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 OAP56520.1 - 0.001 18.5 0.2 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 OAP56520.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 OAP56520.1 - 0.031 15.0 0.0 0.088 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 OAP56520.1 - 0.032 13.7 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 OAP56520.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 OAP56520.1 - 0.12 11.4 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 OAP56520.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.11 OAP56521.1 - 1.3e-30 106.3 25.0 1.3e-30 106.3 17.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF308 PF03729.8 OAP56521.1 - 0.47 10.4 11.6 0.4 10.6 3.0 3.3 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) RasGEF PF00617.14 OAP56522.1 - 1.6e-42 145.3 0.0 2.6e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAP56522.1 - 2.1e-12 47.0 0.2 4.7e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif AA_permease PF00324.16 OAP56523.1 - 4.2e-144 480.4 37.4 4.7e-144 480.2 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP56523.1 - 1.1e-35 122.9 38.7 1.4e-35 122.6 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease Dynamin_N PF00350.18 OAP56524.1 - 8.5e-33 113.5 0.0 1.8e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 OAP56524.1 - 3.1e-14 52.4 0.0 3.4e-13 49.0 0.0 2.3 1 1 0 2 2 2 1 Dynamin central region GED PF02212.13 OAP56524.1 - 2.9e-05 23.8 1.8 0.00042 20.1 0.0 3.3 3 1 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 OAP56524.1 - 0.00032 20.6 0.0 0.0017 18.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAP56524.1 - 0.0057 17.1 0.0 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 OAP56524.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 OAP56524.1 - 0.022 14.0 0.0 1.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 OAP56524.1 - 0.062 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-primase PF09329.6 OAP56525.1 - 7.6e-16 57.4 0.5 1.4e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 OAP56525.1 - 0.13 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.5 OAP56526.1 - 7.6e-72 242.0 0.0 9.3e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) ABC2_membrane PF01061.19 OAP56527.1 - 1.1e-84 282.7 57.0 1.5e-45 154.9 14.7 3.0 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 OAP56527.1 - 1.2e-38 130.8 1.1 3.1e-30 103.8 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 OAP56527.1 - 3.3e-35 121.3 0.0 2.3e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 OAP56527.1 - 6.5e-10 38.5 54.8 1.3e-07 31.0 16.4 3.4 2 2 2 4 4 4 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 OAP56527.1 - 2.3e-08 33.9 0.3 8.1e-08 32.2 0.2 2.0 1 1 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 OAP56527.1 - 1.7e-07 30.8 0.1 0.0003 20.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 OAP56527.1 - 3.4e-06 26.3 0.0 1.7e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 OAP56527.1 - 7.8e-06 26.0 0.0 0.0095 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP56527.1 - 1e-05 24.9 0.0 0.0033 16.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 OAP56527.1 - 9.2e-05 21.9 0.0 0.028 13.8 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 OAP56527.1 - 9.5e-05 22.5 0.1 0.11 12.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP56527.1 - 9.6e-05 22.4 4.0 0.0042 17.0 0.0 3.1 4 0 0 4 4 2 1 AAA ATPase domain AAA_17 PF13207.1 OAP56527.1 - 0.00013 22.7 0.1 0.011 16.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 OAP56527.1 - 0.0016 18.3 0.0 0.46 10.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 OAP56527.1 - 0.0018 17.2 0.0 0.61 8.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 OAP56527.1 - 0.002 17.6 0.4 2.9 7.3 0.0 3.0 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_28 PF13521.1 OAP56527.1 - 0.0021 18.0 2.1 0.0026 17.7 0.1 2.2 3 0 0 3 3 1 1 AAA domain AAA_33 PF13671.1 OAP56527.1 - 0.0023 17.7 0.1 0.39 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 OAP56527.1 - 0.0029 17.2 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 OAP56527.1 - 0.0035 16.9 0.4 0.062 12.9 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 OAP56527.1 - 0.0098 16.2 0.1 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 OAP56527.1 - 0.018 15.3 1.2 0.1 12.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 OAP56527.1 - 0.02 14.6 0.1 0.75 9.5 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 OAP56527.1 - 0.02 14.4 0.3 0.13 11.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 OAP56527.1 - 0.022 15.2 0.0 4.3 7.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein SMC_N PF02463.14 OAP56527.1 - 0.03 13.5 0.0 6.1 5.9 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 OAP56527.1 - 0.037 13.4 0.3 4.4 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 OAP56527.1 - 0.11 11.5 0.0 0.24 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 OAP56527.1 - 0.12 12.5 0.2 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 OAP56527.1 - 0.15 11.7 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase Septin PF00735.13 OAP56527.1 - 0.16 10.9 0.5 8.1 5.3 0.1 2.2 2 0 0 2 2 2 0 Septin Pantoate_ligase PF02569.10 OAP56527.1 - 0.38 9.4 0.0 0.73 8.5 0.0 1.4 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Ribonuclease_3 PF00636.21 OAP56530.1 - 3.3e-16 59.7 0.0 9.2e-16 58.3 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAP56530.1 - 2.8e-13 49.9 0.0 4.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 OAP56530.1 - 0.0025 18.3 0.5 0.0056 17.2 0.2 1.8 1 1 0 1 1 1 1 Double-stranded RNA binding motif DUF2961 PF11175.3 OAP56530.1 - 0.074 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Ank_4 PF13637.1 OAP56530.1 - 0.15 12.5 0.0 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) MRP-S33 PF08293.6 OAP56531.1 - 3.5e-28 97.4 0.1 5.1e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 adh_short_C2 PF13561.1 OAP56532.1 - 1.3e-32 113.4 0.1 1.6e-32 113.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP56532.1 - 2.8e-28 98.9 1.6 4.1e-28 98.3 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP56532.1 - 5.3e-07 29.4 0.2 7.7e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP56532.1 - 0.00034 20.6 0.2 0.00052 20.0 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAP56532.1 - 0.024 14.3 0.3 0.054 13.2 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP56532.1 - 0.045 13.1 0.1 0.084 12.2 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF382 PF04037.8 OAP56533.1 - 2.1e-61 205.3 0.7 4.6e-61 204.3 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 OAP56533.1 - 3.7e-22 77.4 7.5 8.5e-22 76.2 5.2 1.7 1 0 0 1 1 1 1 PSP Lge1 PF11488.3 OAP56533.1 - 0.0099 16.0 0.3 0.034 14.3 0.2 2.0 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 DUF1192 PF06698.6 OAP56533.1 - 0.38 10.6 9.3 5.6 6.8 3.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TFIIB PF00382.14 OAP56534.1 - 7.2e-28 96.2 0.1 1e-13 50.8 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 OAP56534.1 - 5e-10 38.5 0.5 8.5e-10 37.8 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 OAP56534.1 - 0.00012 21.6 0.1 0.00026 20.5 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 OAP56534.1 - 0.014 14.5 0.1 0.03 13.5 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Sigma70_r4_2 PF08281.7 OAP56534.1 - 0.028 13.8 0.0 0.076 12.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 GerE PF00196.14 OAP56534.1 - 0.056 12.7 0.1 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family ATP_sub_h PF10775.4 OAP56535.1 - 1.2e-23 82.6 1.6 1.6e-23 82.1 1.1 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 OAP56535.1 - 0.0078 16.1 0.0 0.0098 15.7 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 AMP-binding PF00501.23 OAP56536.1 - 4.6e-92 308.5 0.0 6.6e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1765 PF08578.5 OAP56536.1 - 1.9e-38 131.3 5.1 4.2e-38 130.2 3.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) AMP-binding_C PF13193.1 OAP56536.1 - 6.5e-12 46.2 0.0 1.4e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Reticulon PF02453.12 OAP56537.1 - 9.7e-29 100.1 1.2 1.7e-28 99.3 0.8 1.4 1 0 0 1 1 1 1 Reticulon FUSC_2 PF13515.1 OAP56537.1 - 0.024 14.5 1.4 0.024 14.5 1.0 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein-like PDZ_1 PF12812.2 OAP56538.1 - 6.3e-54 179.8 0.1 2.3e-34 117.1 0.0 2.9 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.1 OAP56538.1 - 1.1e-14 54.4 0.4 3.8e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 OAP56538.1 - 2.8e-14 52.7 0.2 6.4e-06 25.9 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.19 OAP56538.1 - 1.4e-11 44.3 0.0 6.1e-06 26.3 0.0 3.8 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 OAP56538.1 - 1.1e-06 28.3 0.2 6.3e-06 25.9 0.0 2.2 2 1 0 2 2 2 1 Trypsin Tricorn_PDZ PF14685.1 OAP56538.1 - 0.0033 17.1 0.1 0.1 12.3 0.0 2.9 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 OAP56538.1 - 0.0085 14.5 1.1 0.012 14.0 0.1 1.6 2 0 0 2 2 2 1 Peptidase S46 Ank PF00023.25 OAP56539.1 - 4.8e-26 89.2 0.0 5.7e-08 32.1 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 OAP56539.1 - 1.6e-25 89.2 0.0 4.9e-13 49.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 OAP56539.1 - 2.1e-20 70.7 0.2 3.4e-05 23.6 0.0 5.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 OAP56539.1 - 1.3e-19 69.7 2.7 1.3e-06 28.4 0.0 5.5 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP56539.1 - 2.2e-16 59.8 2.3 1.1e-09 38.5 0.0 4.4 3 1 1 4 4 3 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 OAP56539.1 - 2.3e-11 43.1 0.0 4.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 OAP56539.1 - 1.1e-08 34.8 0.0 2.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 OAP56539.1 - 0.0027 16.7 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.1 OAP56539.1 - 0.0069 16.1 0.0 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 OAP56539.1 - 0.075 12.1 0.0 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Shigella_OspC PF06128.6 OAP56539.1 - 0.17 11.3 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Shigella flexneri OspC protein Ank_2 PF12796.2 OAP56540.1 - 1.7e-90 297.5 14.3 9e-22 77.2 0.0 6.0 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 OAP56540.1 - 1.8e-61 200.9 18.9 2.2e-09 36.6 0.0 11.1 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 OAP56540.1 - 3.2e-56 186.7 10.4 3e-14 53.0 0.0 8.9 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP56540.1 - 1.2e-48 158.2 11.1 5.7e-05 22.9 0.0 11.7 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 OAP56540.1 - 1.1e-45 152.5 14.3 5.5e-10 39.1 0.0 9.9 3 3 7 10 10 10 10 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.1 OAP56540.1 - 0.31 11.4 4.2 23 5.6 0.0 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Peptidase_S8 PF00082.17 OAP56542.1 - 3.6e-25 88.6 0.0 6.4e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Subtilase family SSXT PF05030.7 OAP56543.1 - 1.4e-05 24.5 0.0 0.28 10.7 0.0 2.8 2 0 0 2 2 2 2 SSXT protein (N-terminal region) TSA PF03249.8 OAP56543.1 - 4.5 5.6 19.1 42 2.4 0.0 2.2 2 0 0 2 2 2 0 Type specific antigen DUF4557 PF15101.1 OAP56543.1 - 6.3 6.5 12.4 8.2 6.2 7.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) TPR_11 PF13414.1 OAP56544.1 - 2.5e-07 30.2 14.6 4.9e-05 22.8 2.9 3.9 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 OAP56544.1 - 0.0033 16.9 4.8 2.6 7.7 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 OAP56544.1 - 0.02 15.0 1.8 0.048 13.7 1.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 OAP56544.1 - 0.033 14.1 12.7 0.14 12.1 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF1993 PF09351.5 OAP56544.1 - 0.66 9.8 4.4 6.4 6.6 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF1993) TPR_14 PF13428.1 OAP56544.1 - 0.8 10.5 5.5 2 9.2 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP56544.1 - 4.8 7.9 7.0 1.6 9.5 0.1 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.19 OAP56545.1 - 7.3e-32 110.5 1.9 1.3e-31 109.7 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAP56545.1 - 3.5e-19 69.4 0.4 7.7e-19 68.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAP56545.1 - 2.8e-17 61.9 0.2 5.7e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAP56545.1 - 2e-16 60.4 1.0 4.3e-16 59.3 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain INCENP_ARK-bind PF03941.10 OAP56546.1 - 2.1e-18 65.9 0.3 2.1e-18 65.9 0.2 3.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region UQ_con PF00179.21 OAP56547.1 - 4e-42 142.9 0.0 4.5e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP56547.1 - 0.032 13.9 0.0 0.059 13.1 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B 7tm_1 PF00001.16 OAP56548.1 - 0.033 13.3 0.0 0.056 12.5 0.0 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Mito_carr PF00153.22 OAP56549.1 - 8.9e-62 204.8 7.2 1.5e-21 75.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tox-WTIP PF15654.1 OAP56549.1 - 0.31 10.6 0.1 0.31 10.6 0.1 2.7 3 0 0 3 3 3 0 Toxin with a conserved tryptophan and TIP tripeptide motif Clat_adaptor_s PF01217.15 OAP56550.1 - 5.8e-51 171.9 4.1 4.2e-50 169.1 2.9 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ist1 PF03398.9 OAP56551.1 - 1.4e-55 187.2 0.3 1.7e-55 186.9 0.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Seryl_tRNA_N PF02403.17 OAP56552.1 - 0.23 11.4 1.3 0.32 11.0 0.2 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YL1 PF05764.8 OAP56552.1 - 3.5 7.1 10.3 6.6 6.2 7.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SUN PF03856.8 OAP56553.1 - 1.3e-77 260.4 16.2 1.3e-77 260.4 11.2 1.9 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) Gram_pos_anchor PF00746.16 OAP56553.1 - 0.31 10.8 5.7 0.15 11.8 1.2 2.3 2 0 0 2 2 2 0 Gram positive anchor LCM PF04072.9 OAP56554.1 - 7.8e-22 77.7 0.0 1.5e-21 76.8 0.0 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase zf-RING_2 PF13639.1 OAP56555.1 - 1.6e-07 31.0 6.8 4.1e-07 29.7 4.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAP56555.1 - 1.8e-05 24.7 4.0 1.8e-05 24.7 1.5 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger FANCL_C PF11793.3 OAP56555.1 - 0.00022 21.0 4.5 0.00064 19.6 3.1 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 OAP56555.1 - 0.00024 20.8 3.4 0.00033 20.4 1.4 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Mad3_BUB1_I PF08311.7 OAP56555.1 - 0.0042 16.8 1.7 0.013 15.2 0.6 2.2 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 zf-C3HC4 PF00097.20 OAP56555.1 - 0.0094 15.5 7.2 0.021 14.4 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP56555.1 - 0.026 14.5 7.7 0.11 12.5 5.4 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 OAP56555.1 - 0.044 13.8 6.4 0.13 12.3 4.5 1.9 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 OAP56555.1 - 0.36 10.5 4.9 0.14 11.8 1.5 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.1 OAP56555.1 - 0.37 10.4 4.3 26 4.5 3.0 2.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 OAP56555.1 - 0.42 10.3 4.2 1.1 9.0 2.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 OAP56555.1 - 3.6 7.6 10.0 0.79 9.7 3.9 2.1 2 0 0 2 2 2 0 RING-like domain DUF1227 PF06777.6 OAP56556.1 - 2.4e-60 202.4 0.5 5.4e-60 201.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 OAP56556.1 - 2e-51 173.8 0.1 3.5e-51 173.0 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 OAP56556.1 - 1.4e-43 148.7 0.0 3.5e-43 147.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 OAP56556.1 - 0.00025 19.9 0.0 0.0015 17.4 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 OAP56556.1 - 0.0012 18.4 0.0 0.16 11.4 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAP56556.1 - 0.012 15.7 0.4 2.5 8.2 0.0 3.4 2 1 1 3 3 3 0 AAA domain ResIII PF04851.10 OAP56556.1 - 0.016 15.0 0.0 0.15 11.8 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 OAP56556.1 - 0.046 13.2 0.5 0.32 10.5 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 OAP56556.1 - 0.12 11.3 0.0 5.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Remorin_C PF03763.8 OAP56556.1 - 0.19 11.2 6.8 0.075 12.5 2.6 1.8 2 0 0 2 2 2 0 Remorin, C-terminal region YtxC PF08812.6 OAP56556.1 - 0.39 10.1 3.5 2.7 7.4 0.0 2.8 3 0 0 3 3 3 0 YtxC-like family PhyH PF05721.8 OAP56557.1 - 2.9e-17 63.4 0.0 1.4e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.3 OAP56557.1 - 9.9e-07 27.6 0.7 1.7e-06 26.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain WAK_assoc PF14380.1 OAP56557.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal Sugar_tr PF00083.19 OAP56558.1 - 4.8e-97 325.3 25.2 6e-97 325.0 17.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56558.1 - 1.5e-19 69.9 30.7 1.5e-19 69.9 21.3 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 OAP56558.1 - 1.2e-09 37.2 0.1 1.9e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain OATP PF03137.15 OAP56558.1 - 0.38 8.7 5.4 0.31 9.0 0.4 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PhyH PF05721.8 OAP56559.1 - 1.9e-12 47.6 0.0 3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) OCD_Mu_crystall PF02423.10 OAP56560.1 - 2.5e-14 52.7 0.0 6.2e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 OAP56560.1 - 1.2e-05 25.3 0.0 5.3e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TruB_C PF09142.6 OAP56560.1 - 0.003 17.1 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 tRNA Pseudouridine synthase II, C terminal NAD_binding_7 PF13241.1 OAP56560.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 OAP56560.1 - 0.018 15.5 0.0 0.088 13.3 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 OAP56560.1 - 0.02 15.3 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3739 PF12545.3 OAP56560.1 - 0.02 15.0 0.3 0.098 12.7 0.0 2.0 2 0 0 2 2 2 0 Filamentous haemagglutinin family outer membrane protein NAD_Gly3P_dh_N PF01210.18 OAP56560.1 - 0.033 13.9 0.0 0.088 12.5 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PGA_cap PF09587.5 OAP56561.1 - 3.8e-61 206.6 0.0 5.5e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Aa_trans PF01490.13 OAP56563.1 - 1.1e-80 271.1 23.2 1.5e-80 270.7 16.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FixP_N PF14715.1 OAP56563.1 - 0.9 8.9 2.9 2.4 7.6 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP ABC_tran PF00005.22 OAP56564.1 - 1.5e-46 158.0 0.1 3e-28 98.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 OAP56564.1 - 3.4e-29 102.1 37.7 2e-18 66.8 12.5 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 OAP56564.1 - 1e-14 54.2 2.2 4.6e-06 26.0 0.1 4.2 2 2 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP56564.1 - 2.7e-10 40.6 0.0 0.041 13.8 0.0 4.5 3 1 0 3 3 3 3 AAA domain AAA_23 PF13476.1 OAP56564.1 - 6e-09 36.5 0.1 0.002 18.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAP56564.1 - 2.7e-06 27.5 0.3 0.13 12.3 0.2 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP56564.1 - 4.1e-06 26.2 1.9 0.00042 19.7 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 OAP56564.1 - 4.6e-05 22.4 4.0 0.0093 14.8 0.3 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.1 OAP56564.1 - 4.8e-05 23.4 5.0 0.19 11.6 0.4 3.9 3 1 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 OAP56564.1 - 4.9e-05 22.8 0.1 0.016 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAP56564.1 - 0.00047 20.9 0.1 0.17 12.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAP56564.1 - 0.0021 18.3 0.0 0.26 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 OAP56564.1 - 0.0029 17.5 0.0 0.29 11.0 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 OAP56564.1 - 0.0036 17.0 0.1 0.25 11.0 0.0 2.9 3 1 0 3 3 3 1 Archaeal ATPase AAA_10 PF12846.2 OAP56564.1 - 0.0038 16.6 0.4 0.76 9.1 0.1 2.8 2 1 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 OAP56564.1 - 0.0046 16.7 0.4 0.91 9.3 0.0 3.1 3 0 0 3 3 3 1 Dynamin family cobW PF02492.14 OAP56564.1 - 0.0095 15.3 0.9 3.9 6.8 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 OAP56564.1 - 0.012 15.1 0.2 0.3 10.5 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 OAP56564.1 - 0.015 15.1 0.4 0.015 15.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 RAMP4 PF06624.7 OAP56564.1 - 0.021 14.3 1.1 2.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 AAA_33 PF13671.1 OAP56564.1 - 0.022 14.6 0.7 7.6 6.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 OAP56564.1 - 0.025 13.7 0.1 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 OAP56564.1 - 0.027 14.2 0.5 5.1 6.9 0.1 3.0 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 OAP56564.1 - 0.037 13.6 1.7 2.1 7.9 0.0 3.4 4 1 0 4 4 2 0 NACHT domain SbcCD_C PF13558.1 OAP56564.1 - 0.054 13.4 0.0 17 5.4 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 OAP56564.1 - 0.1 12.2 0.2 3.6 7.2 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 OAP56564.1 - 0.11 13.0 0.0 9.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Adeno_IVa2 PF02456.10 OAP56564.1 - 0.12 11.0 0.0 4.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein NTPase_1 PF03266.10 OAP56564.1 - 0.15 11.7 0.2 0.75 9.4 0.0 2.3 2 0 0 2 2 2 0 NTPase Bac_luciferase PF00296.15 OAP56565.1 - 1.3e-57 195.2 0.3 1.7e-57 194.9 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DLH PF01738.13 OAP56566.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Trypan_PARP PF05887.6 OAP56567.1 - 0.41 10.4 3.5 0.65 9.8 2.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 OAP56567.1 - 1.8 6.9 12.0 1.8 6.9 8.3 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 OAP56567.1 - 4.8 6.1 13.6 5.6 5.9 9.5 1.0 1 0 0 1 1 1 0 BUD22 FAD_binding_4 PF01565.18 OAP56568.1 - 5.9e-28 97.0 0.0 1.3e-27 95.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.14 OAP56568.1 - 3.6e-11 42.8 0.0 6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Sugar_tr PF00083.19 OAP56569.1 - 1.2e-102 343.8 25.5 1.3e-102 343.7 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56569.1 - 4.4e-16 58.5 14.9 4.4e-16 58.5 10.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP56569.1 - 0.00037 18.8 0.8 0.00063 18.0 0.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 OAP56570.1 - 1.9e-53 181.6 0.0 2.4e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 OAP56571.1 - 3.7e-21 75.1 0.0 4.6e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NUDIX PF00293.23 OAP56571.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain Pyr_redox_3 PF13738.1 OAP56572.1 - 8.4e-29 101.0 0.0 2.6e-28 99.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP56572.1 - 5.1e-24 84.3 0.0 2.7e-19 68.7 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP56572.1 - 1.3e-08 34.1 0.0 0.00017 20.6 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP56572.1 - 9.3e-08 32.1 0.0 6.2e-07 29.4 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP56572.1 - 2.2e-07 30.7 0.0 6.6e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP56572.1 - 9.4e-06 24.7 0.1 4.9e-05 22.4 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP56572.1 - 0.00031 21.0 0.2 1.2 9.5 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP56572.1 - 0.0016 18.2 0.1 0.02 14.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 OAP56572.1 - 0.004 17.2 0.1 0.88 9.6 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 OAP56572.1 - 0.0045 15.8 0.3 0.0073 15.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAP56572.1 - 0.033 13.2 0.2 0.065 12.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.14 OAP56572.1 - 0.12 11.4 0.1 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 OAP56572.1 - 0.33 9.3 1.1 0.54 8.6 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans_2 PF11951.3 OAP56573.1 - 5.4e-06 25.2 0.5 8.3e-06 24.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.1 OAP56574.1 - 1.5e-45 155.5 51.0 1.8e-45 155.2 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP56574.1 - 1.1e-14 53.6 36.2 1.9e-14 52.9 25.1 1.2 1 0 0 1 1 1 1 Amino acid permease Mg_trans_NIPA PF05653.9 OAP56575.1 - 2.5e-90 302.5 24.3 3.5e-90 302.0 16.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 OAP56575.1 - 3e-06 27.4 5.7 3e-06 27.4 3.9 3.1 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 OAP56575.1 - 5.6e-05 23.1 6.3 5.6e-05 23.1 4.3 3.1 2 1 1 3 3 3 1 EamA-like transporter family Synaptobrevin PF00957.16 OAP56576.1 - 0.02 14.5 0.8 0.042 13.4 0.5 1.5 1 0 0 1 1 1 0 Synaptobrevin Herpes_BLRF2 PF05812.7 OAP56576.1 - 0.02 14.7 1.2 0.043 13.6 0.8 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TBPIP PF07106.8 OAP56576.1 - 0.025 14.1 1.5 0.059 12.9 1.0 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 OAP56576.1 - 0.038 14.1 0.7 0.086 12.9 0.5 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 OAP56576.1 - 0.093 12.3 4.2 0.18 11.4 2.9 1.5 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 OAP56576.1 - 0.13 12.7 2.7 0.21 12.0 0.5 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 OAP56576.1 - 0.19 11.2 4.0 0.39 10.2 2.8 1.4 1 0 0 1 1 1 0 Septum formation initiator AAA_13 PF13166.1 OAP56576.1 - 0.25 9.7 3.2 3.1 6.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain Prominin PF05478.6 OAP56576.1 - 0.26 8.7 0.3 0.36 8.3 0.2 1.1 1 0 0 1 1 1 0 Prominin bZIP_2 PF07716.10 OAP56576.1 - 1.2 9.0 10.2 3.3 7.6 7.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DUF2024 PF09630.5 OAP56576.1 - 2 8.2 5.2 0.35 10.6 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) Amidase PF01425.16 OAP56577.1 - 1.2e-102 344.0 0.0 1.4e-102 343.8 0.0 1.0 1 0 0 1 1 1 1 Amidase 2OG-FeII_Oxy_2 PF13532.1 OAP56578.1 - 4.7e-36 124.4 0.0 7.3e-35 120.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FUSC_2 PF13515.1 OAP56579.1 - 9.1e-29 99.9 2.5 9.1e-29 99.9 1.8 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 OAP56579.1 - 1.1e-07 30.9 18.1 0.00086 18.0 0.5 4.3 4 0 0 4 4 4 3 Aluminium activated malate transporter DUF2421 PF10334.4 OAP56579.1 - 4.3e-05 23.2 0.3 0.00014 21.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 OAP56579.1 - 0.00015 20.4 21.0 0.031 12.7 2.4 3.8 4 0 0 4 4 4 3 Fusaric acid resistance protein family FUSC-like PF12805.2 OAP56579.1 - 0.0021 17.0 3.5 0.033 13.1 0.2 3.2 2 1 0 2 2 2 1 FUSC-like inner membrane protein yccS DUF2422 PF10337.4 OAP56579.1 - 0.013 14.3 12.6 0.077 11.7 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2422) Peptidase_M50 PF02163.17 OAP56579.1 - 0.027 13.4 0.0 0.039 12.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M50 DUF939 PF06081.6 OAP56579.1 - 0.056 13.2 0.2 0.056 13.2 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF939) DUF2076 PF09849.4 OAP56580.1 - 0.16 12.0 3.7 0.32 11.0 2.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Epimerase PF01370.16 OAP56581.1 - 1.8e-26 93.0 0.0 2.7e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP56581.1 - 6e-09 35.1 0.0 1.9e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 OAP56581.1 - 4.6e-08 32.1 0.0 4e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP56581.1 - 1.1e-07 31.9 0.0 3.9e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 OAP56581.1 - 2.1e-06 26.8 0.0 3.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 OAP56581.1 - 7.1e-05 21.8 0.0 0.00015 20.8 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein IncA PF04156.9 OAP56582.1 - 3 7.4 37.9 0.37 10.3 9.7 4.9 3 1 1 4 4 4 0 IncA protein V_ATPase_I PF01496.14 OAP56582.1 - 3.7 5.2 9.2 9.3 3.9 6.3 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 OAP56582.1 - 7.5 5.5 4.5 17 4.3 3.1 1.5 1 0 0 1 1 1 0 TMPIT-like protein CorA PF01544.13 OAP56583.1 - 2.4e-40 138.3 0.6 2.1e-38 132.0 0.4 2.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Sugar_tr PF00083.19 OAP56584.1 - 6.9e-62 209.4 18.0 7.7e-62 209.3 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56584.1 - 8.4e-12 44.4 17.7 8.4e-12 44.4 12.2 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF3493 PF11998.3 OAP56584.1 - 1.9 8.4 4.4 56 3.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) Fe-ADH PF00465.14 OAP56586.1 - 1.3e-68 231.3 0.5 1.5e-68 231.1 0.3 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAP56586.1 - 2.4e-15 56.5 0.1 3.1e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase COesterase PF00135.23 OAP56587.1 - 5.5e-62 210.1 0.0 8.2e-54 183.2 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP56587.1 - 2.2e-08 33.9 0.0 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold CMD PF02627.15 OAP56588.1 - 7.9e-09 35.2 0.0 1.3e-06 28.1 0.0 2.6 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family HgmA PF04209.8 OAP56589.1 - 2e-137 458.0 0.0 2.3e-137 457.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF3500 PF12006.3 OAP56590.1 - 4.2e-48 163.9 0.0 4.9e-31 107.8 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3500) But2 PF09792.4 OAP56591.1 - 1.1e-05 25.2 0.1 2.4e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain PTCB-BRCT PF12738.2 OAP56592.1 - 2.4e-13 49.7 0.0 5.4e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 OAP56592.1 - 3.5e-09 36.6 0.0 5.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 OAP56592.1 - 0.0036 17.0 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 OAP56592.1 - 0.023 14.7 0.0 0.076 13.1 0.0 1.9 1 1 0 1 1 1 0 Fibronectin type III domain Ribonuclease_P PF00825.13 OAP56593.1 - 0.022 14.6 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease P eIF-1a PF01176.14 OAP56594.1 - 1.9e-28 97.6 0.1 2.8e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.10 OAP56595.1 - 1.9e-24 86.0 0.0 5.2e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 OAP56595.1 - 0.033 14.3 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain HVSL PF09749.4 OAP56595.1 - 0.065 12.2 0.1 0.14 11.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein Patatin PF01734.17 OAP56596.1 - 8.8e-29 100.8 0.0 1.5e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Zn_clus PF00172.13 OAP56597.1 - 2.1e-10 40.2 12.9 3.4e-10 39.6 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP56597.1 - 2.8e-05 23.1 0.0 5.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1664 PF07889.7 OAP56597.1 - 3 7.6 3.7 6.1 6.6 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1466 PF07326.6 OAP56598.1 - 0.017 14.3 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) CinA PF02464.12 OAP56599.1 - 7.9e-26 90.3 0.4 9.5e-19 67.3 0.1 2.0 2 0 0 2 2 2 2 Competence-damaged protein Sugar_tr PF00083.19 OAP56600.1 - 6.4e-76 255.7 23.1 7e-76 255.6 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56600.1 - 2.2e-18 66.0 22.7 2.2e-18 66.0 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 5-FTHF_cyc-lig PF01812.15 OAP56601.1 - 3e-14 53.2 0.0 3.5e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ADH_N PF08240.7 OAP56602.1 - 4.5e-18 64.9 2.3 1.1e-17 63.7 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP56602.1 - 8.8e-10 38.2 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAP56602.1 - 0.00036 19.7 0.1 0.00061 18.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 OAP56602.1 - 0.0011 19.8 0.0 0.0017 19.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ydc2-catalyt PF09159.5 OAP56603.1 - 7.5e-68 228.9 0.0 1e-67 228.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 OAP56603.1 - 0.00019 21.3 0.0 0.055 13.3 0.0 2.8 3 0 0 3 3 3 2 Poxvirus A22 protein Malate_synthase PF01274.17 OAP56604.1 - 4.9e-229 760.6 0.0 5.6e-229 760.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Epimerase PF01370.16 OAP56605.1 - 6.4e-20 71.5 0.0 8.9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP56605.1 - 6e-12 45.0 0.0 9.2e-07 28.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 OAP56605.1 - 2.4e-09 36.3 0.0 3.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAP56605.1 - 1.9e-06 26.9 0.0 1e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 OAP56605.1 - 1.7e-05 24.8 0.0 0.011 15.6 0.0 2.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAP56605.1 - 7.3e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAP56605.1 - 0.025 14.2 0.0 0.35 10.5 0.0 2.3 1 1 1 2 2 2 0 KR domain Polysacc_synt_2 PF02719.10 OAP56605.1 - 0.028 13.3 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 OAP56605.1 - 0.061 13.1 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F_bP_aldolase PF01116.15 OAP56606.1 - 8.2e-75 251.5 0.0 9.9e-75 251.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Methyltransf_24 PF13578.1 OAP56606.1 - 0.068 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CUE PF02845.11 OAP56607.1 - 4.6e-11 41.9 0.0 1.2e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 CUE domain OB_NTP_bind PF07717.11 OAP56608.1 - 2.4e-21 75.6 0.0 6.1e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAP56608.1 - 1.2e-13 50.9 0.1 2.8e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAP56608.1 - 3.3e-12 46.0 0.0 7e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 OAP56608.1 - 7.9e-07 29.2 0.0 2.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 OAP56608.1 - 2.5e-06 27.0 0.3 7.1e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.1 OAP56608.1 - 0.00065 19.3 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAP56608.1 - 0.0026 17.6 0.2 0.57 10.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 OAP56608.1 - 0.0026 18.0 0.1 0.085 13.1 0.1 2.7 1 1 0 1 1 1 1 ABC transporter cobW PF02492.14 OAP56608.1 - 0.011 15.2 0.1 0.075 12.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 OAP56608.1 - 0.017 15.0 0.3 0.056 13.4 0.0 2.0 2 1 0 2 2 1 0 AAA ATPase domain T2SE PF00437.15 OAP56608.1 - 0.021 13.7 0.0 0.04 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 OAP56608.1 - 0.023 14.2 0.1 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavi_DEAD PF07652.9 OAP56608.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Zeta_toxin PF06414.7 OAP56608.1 - 0.028 13.5 3.0 0.031 13.3 0.3 2.5 2 1 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 OAP56608.1 - 0.05 13.4 0.3 0.19 11.5 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAP56608.1 - 0.076 12.5 3.7 0.09 12.3 0.0 2.7 3 1 1 4 4 4 0 AAA domain Zot PF05707.7 OAP56608.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ResIII PF04851.10 OAP56608.1 - 0.11 12.3 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 OAP56608.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 OAP56608.1 - 0.15 11.4 0.5 1.4 8.3 0.0 2.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 OAP56608.1 - 0.35 11.1 1.7 0.42 10.9 0.0 1.9 3 0 0 3 3 2 0 AAA domain DEAD PF00270.24 OAP56609.1 - 7.9e-17 61.2 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP56609.1 - 1.5e-16 60.0 0.2 1.3e-15 57.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain MmgE_PrpD PF03972.9 OAP56609.1 - 0.021 13.0 0.1 0.032 12.3 0.0 1.2 1 0 0 1 1 1 0 MmgE/PrpD family CLCA_N PF08434.6 OAP56609.1 - 0.098 11.8 1.0 0.17 11.0 0.7 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel Peptidase_A22B PF04258.8 OAP56611.1 - 7.9e-53 179.8 4.4 5.4e-52 177.0 3.1 2.2 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 OAP56611.1 - 1.5e-07 30.8 7.9 3.4e-07 29.6 2.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1119) Luciferase_cat PF10285.4 OAP56611.1 - 0.093 11.8 0.1 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Luciferase catalytic domain GSIII_N PF12437.3 OAP56611.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal WH1 PF00568.18 OAP56613.1 - 1.8e-28 98.4 0.1 2.6e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 OAP56613.1 - 0.18 11.4 4.9 1.1 8.9 3.4 2.4 1 1 0 1 1 1 0 WH2 motif CorA PF01544.13 OAP56614.1 - 3.9e-09 35.9 0.3 9e-09 34.7 0.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease_2 PF13520.1 OAP56614.1 - 0.024 13.2 0.1 0.033 12.7 0.1 1.1 1 0 0 1 1 1 0 Amino acid permease DUF1469 PF07332.6 OAP56614.1 - 0.046 13.4 0.6 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Asp PF00026.18 OAP56616.1 - 0.001 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease MFS_1 PF07690.11 OAP56617.1 - 5.6e-33 114.1 24.1 8.3e-33 113.5 16.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP56617.1 - 5.1e-11 41.8 5.4 1e-10 40.7 3.7 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter SPC12 PF06645.8 OAP56617.1 - 0.038 13.8 14.2 3.9 7.3 0.2 5.5 5 0 0 5 5 5 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TRI12 PF06609.8 OAP56617.1 - 0.043 12.0 5.3 0.066 11.3 3.7 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Antifungal_pept PF11410.3 OAP56617.1 - 1.2 9.2 2.9 2.6 8.2 2.0 1.5 1 0 0 1 1 1 0 Antifungal peptide MOSC PF03473.12 OAP56618.1 - 2e-14 53.1 0.0 4e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 OAP56618.1 - 1.2e-05 24.9 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain BRCT PF00533.21 OAP56619.1 - 0.00059 19.9 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HDNR PF15115.1 OAP56619.1 - 0.0017 18.2 0.2 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function with conserved HDNR motif Suf PF05843.9 OAP56619.1 - 0.054 13.2 0.0 0.063 12.9 0.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Meth_synt_2 PF01717.13 OAP56620.1 - 4e-142 472.9 0.0 2.6e-137 457.1 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 OAP56620.1 - 4.6e-124 413.7 0.0 5.6e-112 374.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 OAP56620.1 - 0.4 10.2 4.1 0.34 10.4 0.1 2.8 3 0 0 3 3 3 0 Short C-terminal domain Bac_small_YrzI PF09501.5 OAP56620.1 - 0.9 9.4 3.4 3.5 7.5 2.3 2.0 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Steroid_dh PF02544.11 OAP56621.1 - 2.1e-09 37.3 2.3 1.5e-08 34.5 1.6 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 OAP56621.1 - 0.0015 17.8 2.6 0.0029 16.9 1.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) CorA PF01544.13 OAP56622.1 - 4.8e-09 35.6 0.1 8.9e-09 34.7 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CBFB_NFYA PF02045.10 OAP56622.1 - 3.1e-08 34.0 0.2 7.3e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ALS_ss_C PF10369.4 OAP56623.1 - 3e-19 68.5 0.0 6.3e-18 64.2 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 OAP56623.1 - 5.7e-12 44.8 0.1 5.7e-12 44.8 0.1 2.0 3 0 0 3 3 3 1 ACT domain ACT_5 PF13710.1 OAP56623.1 - 2.1e-09 37.0 0.0 4.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 OAP56623.1 - 0.037 13.7 0.1 7.8 6.2 0.0 2.7 2 0 0 2 2 2 0 ACT domain DUF2346 PF09803.4 OAP56623.1 - 0.073 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) Glyco_hydro_28 PF00295.12 OAP56624.1 - 3.5e-30 105.0 6.2 1.3e-16 60.4 0.7 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Carb_anhydrase PF00194.16 OAP56625.1 - 2.1e-21 76.0 1.3 1.2e-20 73.6 0.9 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF924 PF06041.6 OAP56626.1 - 3.3e-55 186.7 0.0 4.5e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Aa_trans PF01490.13 OAP56627.1 - 3.3e-62 210.3 15.8 3.8e-62 210.0 10.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2077 PF09850.4 OAP56627.1 - 0.1 12.0 0.0 0.34 10.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Rav1p_C PF12234.3 OAP56627.1 - 0.28 9.2 0.0 0.41 8.7 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal eRF1_2 PF03464.10 OAP56628.1 - 4.9e-47 159.6 0.1 8.6e-47 158.8 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 OAP56628.1 - 5.2e-39 133.0 0.6 1.1e-38 131.9 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 OAP56628.1 - 2.7e-28 98.1 0.0 4.9e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 PDT PF00800.13 OAP56629.1 - 6.3e-50 169.2 0.0 9.9e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 OAP56629.1 - 1.8e-05 24.0 0.0 5.4e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 OAP56629.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ACT domain Peptidase_M24 PF00557.19 OAP56630.1 - 9.1e-40 136.4 0.1 2e-39 135.3 0.1 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 OAP56630.1 - 2.6e-28 99.1 0.1 2.1e-24 86.4 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF3384 PF11864.3 OAP56631.1 - 0.0041 15.6 0.2 1.6 7.1 0.1 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3384) IBN_N PF03810.14 OAP56631.1 - 0.0069 16.2 0.4 0.029 14.2 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF445 PF04286.7 OAP56631.1 - 0.03 13.8 0.2 0.55 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Sec8_exocyst PF04048.9 OAP56632.1 - 2.3e-38 130.9 0.9 4.1e-38 130.2 0.0 1.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 OAP56632.1 - 1.5e-09 37.2 0.1 3.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Vps51 PF08700.6 OAP56632.1 - 0.027 14.2 2.3 0.73 9.7 0.0 3.5 4 0 0 4 4 4 0 Vps51/Vps67 AAA_12 PF13087.1 OAP56632.1 - 0.04 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain COG2 PF06148.6 OAP56632.1 - 0.21 11.4 1.7 0.75 9.6 0.1 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Zn_clus PF00172.13 OAP56633.1 - 1.2e-08 34.7 14.2 1.9e-08 34.0 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cwf21 PF08312.7 OAP56634.1 - 2e-17 62.7 15.6 5.5e-17 61.3 10.8 1.8 1 0 0 1 1 1 1 cwf21 domain DUF940 PF06082.6 OAP56634.1 - 0.039 12.5 0.4 0.046 12.2 0.2 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Trans_reg_C PF00486.23 OAP56634.1 - 0.26 11.2 2.0 0.28 11.1 0.2 2.0 2 1 0 2 2 2 0 Transcriptional regulatory protein, C terminal DUF4404 PF14357.1 OAP56634.1 - 0.89 10.0 6.7 0.19 12.1 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF883 PF05957.8 OAP56634.1 - 2.8 8.3 6.5 1.6 9.1 2.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Hus1 PF04005.7 OAP56636.1 - 5.3e-94 314.4 0.0 6.2e-94 314.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein LptE PF04390.7 OAP56636.1 - 0.13 11.9 0.1 0.66 9.6 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide-assembly GAS2 PF02187.12 OAP56637.1 - 0.00011 21.8 0.1 0.00022 20.9 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Glyco_transf_25 PF01755.12 OAP56638.1 - 0.013 15.1 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) IATP PF04568.7 OAP56638.1 - 0.14 12.1 0.6 0.26 11.3 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Oxidored_FMN PF00724.15 OAP56639.1 - 5.3e-51 173.6 0.0 6.4e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Na_H_Exchanger PF00999.16 OAP56640.1 - 6.8e-67 225.6 40.6 8.4e-67 225.3 28.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TelA PF05816.6 OAP56640.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) SNF2_N PF00176.18 OAP56641.1 - 8.7e-84 280.8 1.3 8.7e-84 280.8 0.9 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 OAP56641.1 - 8.3e-21 73.7 0.1 2.4e-20 72.2 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 OAP56641.1 - 6.4e-19 67.5 0.0 8.3e-17 60.8 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 OAP56641.1 - 5.2e-17 61.7 2.6 5.2e-17 61.7 1.8 4.3 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 OAP56641.1 - 2.3e-15 56.1 12.3 2.3e-15 56.1 8.6 3.7 3 0 0 3 3 3 1 HSA QLQ PF08880.6 OAP56641.1 - 3.5e-10 39.1 1.8 1.1e-09 37.4 1.2 2.0 1 0 0 1 1 1 1 QLQ BAR PF03114.13 OAP56642.1 - 1.6e-46 158.6 8.8 2e-46 158.3 6.1 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 OAP56642.1 - 1.8e-05 23.8 3.8 2.5e-05 23.3 2.7 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PMEI PF04043.10 OAP56642.1 - 0.00015 21.7 1.0 0.017 14.9 1.1 2.3 1 1 1 2 2 2 1 Plant invertase/pectin methylesterase inhibitor APG17 PF04108.7 OAP56642.1 - 0.0002 20.3 0.3 0.00034 19.5 0.2 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 GBP_C PF02841.9 OAP56642.1 - 0.22 10.6 11.4 0.015 14.5 4.6 1.4 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DUF4337 PF14235.1 OAP56642.1 - 0.31 10.8 4.5 0.61 9.9 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ribosomal_L2_C PF03947.13 OAP56643.1 - 1e-37 128.8 3.6 1.6e-37 128.1 2.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 OAP56643.1 - 2.3e-17 62.6 0.1 4.7e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Nop14 PF04147.7 OAP56644.1 - 0.24 9.2 10.5 0.42 8.4 7.2 1.4 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 OAP56645.1 - 8.3e-67 225.0 0.0 1.7e-66 224.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56645.1 - 1.5e-50 171.7 0.0 4.1e-50 170.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 OAP56645.1 - 3.5e-30 104.0 0.0 7.1e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 OAP56645.1 - 1.4e-15 57.2 0.0 3.3e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 OAP56645.1 - 1.4e-13 50.4 0.0 3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 OAP56645.1 - 1.8e-06 27.1 0.0 0.0038 16.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 OAP56645.1 - 4e-06 27.2 0.0 8.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 OAP56645.1 - 0.04 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 OAP56645.1 - 0.17 10.6 0.0 0.59 8.9 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 zf-FCS PF06467.9 OAP56646.1 - 0.022 14.3 0.1 0.061 12.9 0.1 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.21 OAP56646.1 - 0.032 14.5 8.7 0.14 12.5 0.4 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP56646.1 - 0.055 13.8 10.6 0.16 12.3 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Lactamase_B PF00753.22 OAP56647.1 - 2.2e-05 24.2 4.4 0.00018 21.2 3.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP56647.1 - 4.8e-05 22.9 0.2 5.6e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FH2 PF02181.18 OAP56648.1 - 1e-80 271.4 6.4 1.3e-80 271.1 4.4 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain RPW8 PF05659.6 OAP56648.1 - 0.04 13.4 0.3 0.45 10.0 0.1 2.6 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Drf_GBD PF06371.8 OAP56649.1 - 1.9e-66 223.0 0.0 1.9e-66 223.0 0.0 1.8 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 OAP56649.1 - 1.6e-52 177.8 1.3 1.6e-52 177.8 0.9 2.7 2 1 1 3 3 3 1 Diaphanous FH3 Domain K_channel_TID PF07941.6 OAP56650.1 - 0.015 15.4 0.4 0.031 14.5 0.3 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain FixQ PF05545.6 OAP56650.1 - 0.63 9.7 3.4 0.21 11.2 0.4 1.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ STE PF02200.11 OAP56651.1 - 2.4e-61 204.7 0.2 4.9e-61 203.6 0.1 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 OAP56651.1 - 2.5e-12 46.3 10.5 3.3e-07 30.2 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP56651.1 - 7.7e-10 38.4 10.2 5.6e-05 23.1 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP56651.1 - 1.6e-09 37.5 3.7 1.6e-09 37.5 2.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 OAP56651.1 - 0.00062 19.5 0.3 0.0017 18.2 0.1 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAP56651.1 - 0.00075 19.5 0.9 0.014 15.5 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.5 OAP56651.1 - 0.0036 17.8 1.4 0.0085 16.6 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zf-RING_3 PF14369.1 OAP56651.1 - 0.025 14.5 0.1 0.059 13.3 0.1 1.6 1 0 0 1 1 1 0 zinc-finger zf-Di19 PF05605.7 OAP56651.1 - 0.049 13.7 1.9 0.11 12.6 1.3 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding tRNA-synt_1g PF09334.6 OAP56651.1 - 0.11 11.1 0.3 0.22 10.1 0.2 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-TRAF PF02176.13 OAP56651.1 - 0.12 12.7 1.9 0.21 11.9 1.3 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger DGF-1_C PF11040.3 OAP56651.1 - 0.7 9.8 3.6 9.7 6.1 0.3 3.0 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF4602 PF15375.1 OAP56652.1 - 1.6e-05 25.0 4.2 1.6e-05 25.0 2.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) His_biosynth PF00977.16 OAP56653.1 - 6.1e-34 117.2 0.0 7.5e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 OAP56653.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF2823 PF11034.3 OAP56655.1 - 3.9e-32 110.1 12.9 4.4e-32 110.0 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Tombus_movement PF05318.7 OAP56655.1 - 7.3 7.2 8.1 62 4.3 5.4 2.1 1 1 0 1 1 1 0 Tombusvirus movement protein Glyoxalase_2 PF12681.2 OAP56656.1 - 2.7e-12 47.2 0.0 3e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP56656.1 - 4.5e-06 26.6 0.0 1.1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_6 PF12697.2 OAP56657.1 - 1e-31 110.5 0.0 1.3e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP56657.1 - 1.4e-18 67.2 0.0 5.7e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP56657.1 - 2.2e-12 46.9 0.0 1.1e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP56657.1 - 3.6e-06 26.7 0.0 8.5e-06 25.5 0.0 1.7 1 1 1 2 2 2 1 Putative lysophospholipase FSH1 PF03959.8 OAP56657.1 - 0.0046 16.4 0.0 0.32 10.3 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase (FSH1) ECH PF00378.15 OAP56658.1 - 9.8e-26 90.3 0.0 1.4e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family UCH PF00443.24 OAP56658.1 - 0.093 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_1 PF00561.15 OAP56659.1 - 2.4e-20 73.0 0.1 2.4e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP56659.1 - 4e-12 46.4 0.7 9.7e-11 41.9 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAP56659.1 - 0.0001 21.8 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase ATP-synt_C PF00137.16 OAP56660.1 - 3.9e-25 87.5 32.1 1.7e-13 50.2 6.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.17 OAP56661.1 - 2.7e-78 263.1 0.0 1.2e-77 260.9 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 OAP56661.1 - 2.8e-41 140.6 0.1 5.9e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 OAP56661.1 - 1.5e-38 132.5 0.0 2.5e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 OAP56661.1 - 1e-14 54.0 0.0 1.3e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Brix PF04427.13 OAP56662.1 - 6.3e-39 133.6 0.1 9e-39 133.1 0.1 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 OAP56662.1 - 0.11 10.4 21.7 0.14 10.0 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family Ebola_NP PF05505.7 OAP56662.1 - 8.7 4.2 11.3 11 3.8 7.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein tRNA-synt_2b PF00587.20 OAP56663.1 - 1.9e-66 222.9 0.1 3.4e-66 222.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAP56663.1 - 1.5e-21 76.1 0.0 1.5e-21 76.1 0.0 3.2 4 1 1 5 5 5 1 Anticodon binding domain Tenui_NCP PF04876.7 OAP56663.1 - 0.077 12.5 0.1 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein FAD_binding_3 PF01494.14 OAP56664.1 - 7.2e-53 179.8 0.0 9.7e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP56664.1 - 8e-10 38.1 1.3 9.7e-05 21.4 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP56664.1 - 2.1e-07 30.1 0.4 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 OAP56664.1 - 1.7e-06 28.3 0.1 0.0016 18.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 OAP56664.1 - 0.0001 21.7 0.2 0.00022 20.6 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 OAP56664.1 - 0.00014 20.5 0.1 0.0081 14.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAP56664.1 - 0.00044 20.2 0.1 0.011 15.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP56664.1 - 0.0012 18.7 0.2 0.0033 17.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 OAP56664.1 - 0.026 14.7 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 OAP56664.1 - 0.032 13.3 0.1 0.22 10.5 0.0 2.2 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 OAP56664.1 - 0.047 12.7 0.2 7 5.6 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP56664.1 - 0.063 13.3 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAP56664.1 - 0.13 12.2 0.0 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.9 OAP56664.1 - 0.16 10.5 0.1 0.47 9.0 0.2 1.6 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 OAP56664.1 - 0.17 10.7 0.2 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD-oxidase_C PF02913.14 OAP56665.1 - 1.1e-46 159.1 2.4 1.7e-46 158.6 1.7 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAP56665.1 - 8.8e-39 132.1 0.6 3.4e-38 130.2 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain MFS_1 PF07690.11 OAP56666.1 - 2e-29 102.4 31.5 2.5e-22 79.1 9.1 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily TMEM237 PF15383.1 OAP56666.1 - 0.0088 15.1 1.0 0.097 11.7 0.0 2.3 2 0 0 2 2 2 1 Transmembrane protein 237 MFS_1_like PF12832.2 OAP56666.1 - 0.02 14.6 3.2 0.027 14.2 0.2 2.5 2 0 0 2 2 2 0 MFS_1 like family Fungal_trans PF04082.13 OAP56667.1 - 2.1e-25 89.0 3.0 3.1e-25 88.5 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56667.1 - 2e-05 24.4 12.1 4.2e-05 23.3 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 OAP56668.1 - 7.2e-26 90.2 0.0 1.1e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP56668.1 - 2.2e-13 51.2 0.0 3.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP56668.1 - 4.2e-11 42.5 0.0 9e-10 38.2 0.0 2.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 OAP56668.1 - 0.043 13.8 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding FAA_hydrolase PF01557.13 OAP56669.1 - 1.9e-08 34.0 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TFIIF_alpha PF05793.7 OAP56670.1 - 0.043 12.1 10.7 0.057 11.7 7.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Epimerase PF01370.16 OAP56671.1 - 5.6e-10 39.0 0.0 1.3e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP56671.1 - 8.9e-10 38.8 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 OAP56671.1 - 7e-06 25.1 0.1 0.00072 18.5 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 OAP56671.1 - 0.00056 19.8 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 OAP56671.1 - 0.0048 15.8 0.0 0.088 11.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 OAP56671.1 - 0.0088 15.3 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DUF410 PF04190.8 OAP56672.1 - 6.1e-46 157.0 0.0 7.8e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Response_reg PF00072.19 OAP56673.1 - 7.8e-20 70.9 0.0 3.5e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain SRP-alpha_N PF04086.8 OAP56673.1 - 0.066 12.5 12.4 0.082 12.2 7.2 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RRM_1 PF00076.17 OAP56674.1 - 2.1e-15 56.0 0.0 3.1e-13 49.1 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP56674.1 - 1.4e-11 44.2 0.0 3e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UBA_4 PF14555.1 OAP56675.1 - 1.8e-09 36.9 0.0 6.2e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain UBA PF00627.26 OAP56675.1 - 0.047 13.5 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 UBA/TS-N domain DUF4140 PF13600.1 OAP56675.1 - 0.24 11.8 4.2 4.2 7.8 0.0 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Syntaxin PF00804.20 OAP56675.1 - 7.9 6.7 13.4 7.2 6.8 0.9 2.7 2 1 1 3 3 3 0 Syntaxin Pkinase PF00069.20 OAP56676.1 - 2.9e-55 187.2 0.0 5e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56676.1 - 8.2e-23 80.7 0.0 7.5e-14 51.4 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 OAP56676.1 - 0.0081 15.1 0.2 0.41 9.5 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 OAP56676.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 OAP56676.1 - 0.044 12.6 0.0 0.76 8.5 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 FAM176 PF14851.1 OAP56676.1 - 0.47 10.1 2.9 0.76 9.4 2.0 1.2 1 0 0 1 1 1 0 FAM176 family Gly_transf_sug PF04488.10 OAP56677.1 - 8.7e-13 48.5 0.0 2.4e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif GRAM PF02893.15 OAP56678.1 - 5.5e-17 61.0 0.4 2e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 GRAM domain DUF972 PF06156.8 OAP56679.1 - 0.29 11.4 2.6 8.9 6.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Striatin PF08232.7 OAP56679.1 - 0.9 9.8 12.5 0.52 10.6 2.0 3.3 3 0 0 3 3 3 0 Striatin family CASP_C PF08172.7 OAP56679.1 - 1.4 7.8 7.3 0.12 11.3 1.4 1.9 2 0 0 2 2 2 0 CASP C terminal Mg_trans_NIPA PF05653.9 OAP56680.1 - 3.1e-66 223.3 4.4 9e-65 218.5 1.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 OAP56680.1 - 3.4e-05 23.9 1.7 3.4e-05 23.9 1.2 3.6 2 1 2 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 OAP56680.1 - 0.0037 17.3 0.6 0.0037 17.3 0.4 4.3 4 1 1 5 5 5 1 EamA-like transporter family DUF914 PF06027.7 OAP56680.1 - 0.056 12.2 0.0 0.056 12.2 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) DUF872 PF05915.7 OAP56680.1 - 0.1 12.4 2.1 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3431 PF11913.3 OAP56681.1 - 8.3e-81 270.6 0.3 9.8e-81 270.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_hydro_47 PF01532.15 OAP56682.1 - 6.8e-140 466.7 0.0 7.6e-140 466.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_1 PF00076.17 OAP56683.1 - 1.3e-17 63.2 0.0 1.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP56683.1 - 1.5e-12 47.3 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 OAP56683.1 - 2.2e-08 34.4 2.6 2.2e-08 34.4 1.8 3.8 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 OAP56683.1 - 1.3e-06 28.1 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_3 PF07859.8 OAP56684.1 - 9.9e-43 146.1 0.0 1.5e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP56684.1 - 0.0006 19.5 0.0 0.00096 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 OAP56684.1 - 0.031 12.9 0.0 0.073 11.7 0.0 1.5 1 1 0 1 1 1 0 Carboxylesterase family Peptidase_S9 PF00326.16 OAP56684.1 - 0.13 11.4 0.0 0.78 8.9 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family WD40 PF00400.27 OAP56685.1 - 2.2e-21 74.8 18.9 1.6e-07 30.9 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Phospholip_B PF04916.8 OAP56685.1 - 0.032 12.3 0.0 0.045 11.8 0.0 1.1 1 0 0 1 1 1 0 Phospholipase B MIP PF00230.15 OAP56686.1 - 9.8e-53 178.9 3.8 1.2e-52 178.6 2.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein OsmC PF02566.14 OAP56687.1 - 4.7e-19 68.4 0.0 7.8e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein C2-set_2 PF08205.7 OAP56687.1 - 0.074 12.9 0.3 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain CVNH PF08881.5 OAP56688.1 - 3.2e-33 114.0 0.9 5.1e-33 113.4 0.6 1.3 1 0 0 1 1 1 1 CVNH domain Gly-zipper_OmpA PF13436.1 OAP56688.1 - 0.0006 19.4 12.7 0.00062 19.4 0.5 2.7 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 OAP56688.1 - 0.00071 19.1 14.8 0.00071 19.1 10.3 2.4 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF533 PF04391.7 OAP56688.1 - 0.0013 18.1 21.2 0.0098 15.2 1.8 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF533) Gly-zipper_Omp PF13488.1 OAP56688.1 - 0.0042 16.6 11.3 0.0042 16.6 7.9 2.3 2 0 0 2 2 2 1 Glycine zipper Zip PF02535.17 OAP56688.1 - 0.0098 14.9 1.4 0.014 14.4 1.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4366 PF14283.1 OAP56688.1 - 0.014 14.8 1.1 0.023 14.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ABA_WDS PF02496.11 OAP56688.1 - 0.024 14.7 1.8 0.024 14.7 1.3 3.2 2 1 1 3 3 3 0 ABA/WDS induced protein BAF1_ABF1 PF04684.8 OAP56688.1 - 0.045 12.6 16.8 0.075 11.8 11.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Oleosin PF01277.12 OAP56688.1 - 0.063 12.8 0.4 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 Oleosin Suf PF05843.9 OAP56688.1 - 0.34 10.6 5.4 0.62 9.7 3.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 OAP56688.1 - 0.37 10.6 3.9 0.61 9.9 2.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 OAP56688.1 - 0.99 8.1 5.9 1.4 7.7 4.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Gly-zipper_YMGG PF13441.1 OAP56688.1 - 1.4 8.5 22.5 0.041 13.3 8.4 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper CDK5_activator PF03261.10 OAP56688.1 - 1.6 7.9 6.6 2.4 7.4 4.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Bacteriocin_IIc PF10439.4 OAP56688.1 - 2.2 8.4 10.1 8.3 6.6 4.9 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Claudin_2 PF13903.1 OAP56688.1 - 2.6 7.7 4.1 5.7 6.5 2.9 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction THRAP3_BCLAF1 PF15440.1 OAP56688.1 - 2.9 6.4 26.3 0.18 10.4 8.2 2.1 2 0 0 2 2 2 0 THRAP3/BCLAF1 family SR-25 PF10500.4 OAP56688.1 - 6.2 6.2 25.5 16 4.9 17.7 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4175 PF13779.1 OAP56688.1 - 7.9 4.0 17.0 15 3.1 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NAD_kinase PF01513.16 OAP56690.1 - 6e-50 169.6 0.1 8e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 OAP56690.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain YppF PF14178.1 OAP56690.1 - 0.044 13.3 0.1 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 YppF-like protein Acyltransferase PF01553.16 OAP56691.1 - 7.1e-25 86.9 0.0 1.2e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Sulfotransfer_3 PF13469.1 OAP56692.1 - 0.082 13.8 0.2 0.17 12.8 0.2 1.5 1 1 0 1 1 1 0 Sulfotransferase family Sod_Cu PF00080.15 OAP56694.1 - 1.4e-46 158.2 6.5 1.6e-46 157.9 4.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CRAL_TRIO PF00650.15 OAP56695.1 - 6.1e-22 77.8 0.0 9.1e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAP56695.1 - 2.4e-05 24.3 0.0 0.00011 22.2 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain NADH_B2 PF14813.1 OAP56696.1 - 0.036 13.7 0.1 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 HAD PF12710.2 OAP56697.1 - 1.7e-34 119.7 0.1 5.5e-34 118.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 OAP56697.1 - 2.2e-30 104.9 0.1 4.2e-30 104.0 0.1 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 OAP56697.1 - 9.3e-28 96.8 0.0 1.9e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAP56697.1 - 4.5e-16 59.9 0.1 8.2e-11 42.7 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP56697.1 - 4.6e-05 23.2 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_C PF00689.16 OAP56697.1 - 6.2e-05 22.6 4.6 6.2e-05 22.6 3.2 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 OAP56697.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAP56697.1 - 0.0085 15.6 0.1 0.65 9.5 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NAP PF00956.13 OAP56698.1 - 1.5e-83 279.7 9.3 1.5e-83 279.7 6.4 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) YuzL PF14115.1 OAP56698.1 - 0.059 13.6 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 YuzL-like protein Myosin_head PF00063.16 OAP56699.1 - 2.2e-245 815.9 2.2 2.2e-245 815.9 1.5 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 OAP56699.1 - 9.4e-35 118.6 3.4 2.9e-34 117.0 2.3 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 OAP56699.1 - 5e-12 44.3 29.9 0.0038 16.7 0.1 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 OAP56699.1 - 0.00076 19.6 0.2 0.0062 16.6 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 OAP56699.1 - 0.0033 17.1 1.3 0.01 15.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain GAS PF13851.1 OAP56699.1 - 0.0036 16.5 11.2 0.0036 16.5 7.8 3.1 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding AAA_16 PF13191.1 OAP56699.1 - 0.013 15.4 2.7 0.13 12.2 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain Reo_sigmaC PF04582.7 OAP56699.1 - 0.02 14.0 2.9 0.05 12.7 2.0 1.7 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AAA_10 PF12846.2 OAP56699.1 - 0.021 14.2 0.1 0.021 14.2 0.0 2.3 3 0 0 3 3 3 0 AAA-like domain Myosin_tail_1 PF01576.14 OAP56699.1 - 0.032 11.9 26.5 0.0064 14.2 4.8 2.2 1 1 1 2 2 2 0 Myosin tail IncA PF04156.9 OAP56699.1 - 0.13 11.8 27.8 0.8 9.2 4.5 2.7 1 1 1 2 2 2 0 IncA protein DUF869 PF05911.6 OAP56699.1 - 0.2 9.8 18.5 0.4 8.8 8.3 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) zf-C4H2 PF10146.4 OAP56699.1 - 0.23 11.4 5.1 0.69 9.8 3.5 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein DegQ PF08181.6 OAP56699.1 - 0.41 10.4 9.2 0.021 14.5 1.0 2.9 2 0 0 2 2 2 0 DegQ (SacQ) family ABC_tran PF00005.22 OAP56699.1 - 0.88 9.8 0.0 0.88 9.8 0.0 3.1 2 1 0 2 2 1 0 ABC transporter FlaC_arch PF05377.6 OAP56699.1 - 4.4 7.2 8.3 4.5 7.2 0.2 3.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CCDC155 PF14662.1 OAP56699.1 - 4.6 6.7 33.3 0.025 14.2 5.5 3.5 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 APG6 PF04111.7 OAP56699.1 - 7.9 5.4 26.1 3 6.7 5.2 2.7 1 1 1 2 2 2 0 Autophagy protein Apg6 HpcH_HpaI PF03328.9 OAP56702.1 - 2.7e-38 131.0 0.0 3.5e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TauD PF02668.11 OAP56703.1 - 4.1e-46 157.7 0.5 4.8e-46 157.5 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.1 OAP56703.1 - 0.11 13.0 1.0 8 7.0 0.0 2.9 2 1 1 3 3 3 0 non-haem dioxygenase in morphine synthesis N-terminal FMN_dh PF01070.13 OAP56704.1 - 8.5e-117 389.9 0.0 1e-116 389.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 OAP56704.1 - 0.00027 19.9 0.0 0.00053 19.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAP56704.1 - 0.0011 17.9 0.5 0.0085 15.0 0.2 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 OAP56704.1 - 0.0017 17.3 0.4 0.25 10.2 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase NMO PF03060.10 OAP56704.1 - 0.17 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Fungal_trans PF04082.13 OAP56705.1 - 6.4e-17 61.2 0.6 1.1e-16 60.4 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_18 PF13238.1 OAP56706.1 - 2.8e-23 82.6 0.0 8e-23 81.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAP56706.1 - 9.3e-14 52.2 0.2 3.9e-13 50.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 OAP56706.1 - 0.0011 18.6 0.5 0.0022 17.7 0.3 1.5 1 0 0 1 1 1 1 NTPase MobB PF03205.9 OAP56706.1 - 0.0024 17.6 0.1 0.005 16.5 0.0 1.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 OAP56706.1 - 0.0024 18.0 0.0 0.0039 17.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 OAP56706.1 - 0.0038 17.3 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 OAP56706.1 - 0.0053 16.7 0.5 0.0053 16.7 0.4 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP56706.1 - 0.0054 16.8 0.4 0.011 15.8 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAP56706.1 - 0.012 14.9 0.1 0.064 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 OAP56706.1 - 0.016 14.6 0.5 0.047 13.1 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 OAP56706.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 OAP56706.1 - 0.019 15.4 0.0 0.035 14.5 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein KTI12 PF08433.5 OAP56706.1 - 0.02 14.1 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 OAP56706.1 - 0.025 14.5 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 OAP56706.1 - 0.041 13.4 0.5 0.11 12.0 0.3 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAP56706.1 - 0.043 13.5 1.0 0.078 12.7 0.7 1.4 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 OAP56706.1 - 0.047 13.1 0.1 0.085 12.2 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 OAP56706.1 - 0.048 12.5 0.4 0.34 9.7 0.2 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 OAP56706.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Mg_chelatase PF01078.16 OAP56706.1 - 0.094 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 OAP56706.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 2 0 0 2 2 1 0 NACHT domain AAA_33 PF13671.1 OAP56706.1 - 0.12 12.2 0.6 0.77 9.6 0.4 2.1 1 1 0 1 1 1 0 AAA domain Ham1p_like PF01725.11 OAP56707.1 - 1.5e-50 171.2 0.0 1.7e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.8 OAP56708.1 - 1.6e-60 203.9 0.0 2.1e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 OAP56708.1 - 0.0044 17.1 0.2 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 OAP56708.1 - 0.0045 17.1 2.3 0.1 12.8 0.0 3.0 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 OAP56708.1 - 0.065 13.5 0.3 0.27 11.6 0.2 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger AA_kinase PF00696.23 OAP56709.1 - 3.2e-43 148.0 0.0 5.1e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 OAP56709.1 - 8.4e-12 44.4 1.7 2e-10 40.0 0.2 2.5 2 0 0 2 2 2 1 ACT domain ACT PF01842.20 OAP56709.1 - 1.2e-09 37.4 0.4 9.5e-09 34.5 0.0 2.6 3 0 0 3 3 3 1 ACT domain Fork_head PF00250.13 OAP56710.1 - 2.9e-31 107.3 0.2 5.6e-31 106.4 0.2 1.4 1 0 0 1 1 1 1 Fork head domain Dyp_perox PF04261.7 OAP56711.1 - 3.5e-94 315.0 0.0 4.2e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family AlcCBM31 PF11606.3 OAP56711.1 - 0.031 14.2 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein Ribosomal_S10 PF00338.17 OAP56712.1 - 2e-25 88.4 0.0 3.7e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GMC_oxred_N PF00732.14 OAP56713.1 - 2.2e-63 214.1 0.0 3.3e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP56713.1 - 1.1e-37 129.4 0.0 1.7e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAP56713.1 - 1.6e-05 23.9 0.1 0.022 13.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP56713.1 - 0.00031 19.7 3.2 0.0019 17.1 1.5 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP56713.1 - 0.019 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP56713.1 - 0.019 14.9 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 OAP56713.1 - 0.053 13.5 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 OAP56713.1 - 0.16 12.3 0.5 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_1b PF00579.20 OAP56714.1 - 9.2e-67 225.2 0.0 1.2e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Abhydrolase_6 PF12697.2 OAP56715.1 - 1.3e-30 106.9 0.1 1.8e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP56715.1 - 1.3e-20 74.0 0.1 6.2e-20 71.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP56715.1 - 1.2e-13 51.0 0.0 3.3e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAP56715.1 - 6.6e-09 36.3 0.1 9.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 OAP56715.1 - 9.5e-06 25.3 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 OAP56715.1 - 4.3e-05 23.0 0.0 7.4e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 OAP56715.1 - 0.0065 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 OAP56715.1 - 0.009 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 OAP56715.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ndr PF03096.9 OAP56715.1 - 0.079 11.4 0.0 0.17 10.3 0.0 1.4 2 0 0 2 2 2 0 Ndr family Chlorophyllase2 PF12740.2 OAP56715.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Ribosomal_S3Ae PF01015.13 OAP56716.1 - 3.7e-82 274.3 5.3 4.4e-82 274.1 3.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 OAP56716.1 - 0.033 14.3 0.5 0.11 12.6 0.0 2.0 2 1 1 3 3 3 0 Syntaxin tRNA-synt_2b PF00587.20 OAP56717.1 - 7.5e-33 113.5 0.1 1.4e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 OAP56717.1 - 1.2e-12 47.8 5.5 1.2e-12 47.8 3.8 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Cytochrom_C552 PF02335.10 OAP56717.1 - 0.065 11.9 0.1 0.065 11.9 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c552 His_Phos_2 PF00328.17 OAP56717.1 - 1.6 7.9 5.3 2.9 7.1 2.7 1.8 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) Ras PF00071.17 OAP56718.1 - 1e-47 161.5 0.3 1.2e-47 161.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP56718.1 - 2.1e-17 63.7 0.0 3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP56718.1 - 1.5e-08 34.0 0.0 1.7e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAP56718.1 - 4.5e-07 29.4 0.4 4.3e-06 26.2 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAP56718.1 - 5.6e-06 26.3 0.0 9.3e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAP56718.1 - 2.9e-05 23.3 0.1 5.1e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 OAP56718.1 - 0.00053 19.3 0.1 0.0059 15.9 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 OAP56718.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma70_ner PF04546.8 OAP56718.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region WAPL PF07814.8 OAP56719.1 - 1.2e-15 57.1 5.6 1.8e-15 56.5 3.9 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Terpene_synth PF01397.16 OAP56719.1 - 0.038 13.3 0.3 0.56 9.5 0.1 2.7 1 1 1 2 2 2 0 Terpene synthase, N-terminal domain UPRTase PF14681.1 OAP56720.1 - 3.5e-79 264.7 0.0 4.4e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAP56720.1 - 2.6e-05 23.9 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 OAP56720.1 - 0.1 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) 2-Hacid_dh_C PF02826.14 OAP56721.1 - 1.3e-51 174.3 0.0 2.1e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP56721.1 - 2.8e-36 123.9 0.0 4.3e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP56721.1 - 0.00016 21.5 0.2 0.00047 20.0 0.1 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 OAP56721.1 - 0.0025 17.2 0.0 0.0065 15.9 0.0 1.8 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.16 OAP56721.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 OAP56721.1 - 0.073 12.4 0.1 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 OAP56721.1 - 0.089 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Ribosomal_L19e PF01280.15 OAP56723.1 - 2.9e-61 205.5 9.0 2.9e-61 205.5 6.3 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 OAP56723.1 - 0.042 13.0 2.6 0.044 12.9 1.8 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4239 PF14023.1 OAP56723.1 - 0.26 10.6 1.7 0.36 10.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Sec62 PF03839.11 OAP56723.1 - 0.49 9.7 4.2 26 4.1 3.5 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 Endonuc_Holl PF10107.4 OAP56723.1 - 1.1 8.9 6.3 2.1 8.0 4.4 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase KilA-N PF04383.8 OAP56724.1 - 0.00024 20.6 0.0 0.0027 17.2 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Elf1 PF05129.8 OAP56725.1 - 2.4e-29 100.8 0.7 2.9e-29 100.5 0.5 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Gly-zipper_OmpA PF13436.1 OAP56725.1 - 0.00021 20.9 3.5 0.00031 20.3 2.4 1.2 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain zf-CHY PF05495.7 OAP56725.1 - 0.033 14.3 1.3 0.056 13.6 0.2 1.7 2 0 0 2 2 2 0 CHY zinc finger EST1_DNA_bind PF10373.4 OAP56725.1 - 0.034 13.3 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Gin PF10764.4 OAP56725.1 - 0.17 11.6 1.0 4.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-C2H2_6 PF13912.1 OAP56725.1 - 1.8 8.5 8.1 0.3 11.0 0.5 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger GTP_CH_N PF12471.3 OAP56726.1 - 7.3e-93 309.6 0.0 1.1e-92 309.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 OAP56726.1 - 6.2e-17 61.3 0.0 1.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II SHMT PF00464.14 OAP56728.1 - 6.8e-198 656.9 0.0 7.9e-198 656.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 OAP56728.1 - 0.05 12.7 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.23 OAP56730.1 - 6.7e-79 265.2 0.0 8.2e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP56730.1 - 5.2e-16 59.3 0.0 2.9e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AdoMet_MTase PF07757.8 OAP56731.1 - 3.5e-35 120.4 0.0 5.8e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 OAP56731.1 - 0.081 12.6 0.0 0.35 10.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Sec34 PF04136.10 OAP56732.1 - 2.8e-28 98.5 0.5 6.6e-28 97.3 0.3 1.6 1 0 0 1 1 1 1 Sec34-like family Apolipoprotein PF01442.13 OAP56732.1 - 2 7.8 8.5 0.16 11.4 0.3 2.7 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain RCC1 PF00415.13 OAP56733.1 - 1.2e-30 105.4 3.2 2.6e-07 30.7 0.0 7.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAP56733.1 - 5.6e-11 41.7 24.4 4.6e-08 32.4 0.0 6.4 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat RskA PF10099.4 OAP56733.1 - 0.034 13.8 3.4 0.06 13.0 2.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ASF1_hist_chap PF04729.8 OAP56734.1 - 2.6e-67 225.2 0.0 4.1e-67 224.6 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 OAP56734.1 - 0.023 12.6 31.0 0.029 12.3 21.5 1.0 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 OAP56735.1 - 3.6e-75 253.2 4.1 1.7e-74 251.0 0.0 3.2 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 OAP56735.1 - 4.9e-05 23.5 0.1 0.18 12.5 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Piwi PF02171.12 OAP56736.1 - 4.3e-67 226.2 0.1 6.2e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 OAP56736.1 - 5.6e-19 67.2 0.0 1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 OAP56736.1 - 2.2e-18 65.8 0.1 3.9e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 PAZ domain DUF566 PF04484.7 OAP56736.1 - 4.2 6.7 6.9 7 6.0 4.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2834 PF11196.3 OAP56737.1 - 0.0075 16.4 1.3 0.013 15.5 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2834) p450 PF00067.17 OAP56739.1 - 1.7e-59 201.5 0.0 2.3e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_7 PF03441.9 OAP56740.1 - 1.2e-57 195.2 0.0 1.6e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAP56740.1 - 7.7e-19 68.0 0.0 1.4e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase zf-C2H2 PF00096.21 OAP56741.1 - 7.2e-11 41.7 13.1 1.2e-05 25.3 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP56741.1 - 2.7e-09 36.6 8.0 5.2e-05 23.2 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP56741.1 - 3.5e-08 33.3 11.5 8.7e-07 28.9 1.5 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 OAP56741.1 - 0.00022 21.2 7.9 0.021 15.0 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 OAP56741.1 - 0.00062 19.8 3.0 0.015 15.4 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAP56741.1 - 0.016 15.1 4.3 0.45 10.4 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 OAP56741.1 - 0.23 11.7 0.2 0.23 11.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 OAP56741.1 - 0.47 10.2 4.0 0.24 11.1 0.2 2.1 2 0 0 2 2 2 0 BED zinc finger F-box-like_2 PF13013.1 OAP56742.1 - 0.016 14.9 0.2 0.04 13.6 0.0 1.8 2 1 0 2 2 2 0 F-box-like domain DUF1687 PF07955.6 OAP56743.1 - 1.7e-15 57.1 0.1 9.1e-15 54.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 OAP56743.1 - 0.00045 20.2 0.0 0.029 14.4 0.0 2.6 1 1 1 2 2 2 1 ArsC family DUF3665 PF12427.3 OAP56743.1 - 0.29 10.5 1.2 1 8.7 0.8 2.0 1 1 0 1 1 1 0 Branched-chain amino acid aminotransferase Glyco_hydro_76 PF03663.9 OAP56744.1 - 1.4e-153 511.6 11.5 1.7e-153 511.3 8.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 OAP56744.1 - 0.18 10.7 4.5 1.4 7.8 0.0 2.9 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 CBP4 PF07960.6 OAP56745.1 - 2.6e-27 94.9 0.4 2.8e-27 94.8 0.3 1.0 1 0 0 1 1 1 1 CBP4 DPCD PF14913.1 OAP56745.1 - 0.018 14.1 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 DPCD protein family DUF4200 PF13863.1 OAP56745.1 - 0.028 14.3 6.3 0.036 14.0 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) OmpH PF03938.9 OAP56745.1 - 0.85 9.5 5.2 1.1 9.1 3.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Synaptobrevin PF00957.16 OAP56746.1 - 5.9e-34 115.5 1.7 6.6e-34 115.3 1.2 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF515 PF04415.7 OAP56746.1 - 0.12 10.6 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1035 PF06281.7 OAP56746.1 - 0.5 10.1 3.3 0.73 9.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF619 PF04768.8 OAP56747.1 - 6.8e-50 168.8 0.1 1.3e-49 167.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 OAP56747.1 - 2.3e-31 108.6 0.0 5.1e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 OAP56747.1 - 9.8e-24 84.2 0.0 2e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 OAP56747.1 - 0.016 15.1 0.0 0.065 13.1 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 OAP56747.1 - 0.089 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 OAP56747.1 - 0.09 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Rad21_Rec8_N PF04825.8 OAP56748.1 - 3.1e-21 75.4 0.0 5.5e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein DUF1849 PF08904.6 OAP56748.1 - 0.37 10.0 3.0 0.16 11.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1849) Sel1 PF08238.7 OAP56749.1 - 5.6e-46 153.9 30.3 7.6e-08 32.7 0.4 8.5 8 0 0 8 8 8 7 Sel1 repeat TPR_17 PF13431.1 OAP56749.1 - 0.0087 16.1 0.0 10 6.6 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP56749.1 - 0.57 10.9 11.5 0.62 10.8 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP56749.1 - 1.2 9.7 17.0 0.6 10.6 0.0 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP56749.1 - 5.5 7.7 16.1 15 6.4 0.1 5.6 5 1 0 6 6 6 0 Tetratricopeptide repeat FAD_binding_3 PF01494.14 OAP56750.1 - 3.6e-62 210.4 0.3 4.5e-62 210.1 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 OAP56750.1 - 2.8e-05 23.7 0.0 5.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Trp_halogenase PF04820.9 OAP56750.1 - 6.2e-05 21.8 0.0 0.00017 20.3 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.19 OAP56750.1 - 0.00019 20.4 0.2 0.00019 20.4 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP56750.1 - 0.00053 19.1 0.0 0.0015 17.6 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 OAP56750.1 - 0.005 16.7 0.1 0.012 15.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP56750.1 - 0.0068 15.5 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP56750.1 - 0.013 14.3 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 OAP56750.1 - 0.015 15.7 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP56750.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP56750.1 - 0.037 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP56750.1 - 0.042 12.3 0.1 0.1 11.0 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein MPC PF03650.8 OAP56751.1 - 1.5e-41 141.0 0.3 2.4e-41 140.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 OAP56751.1 - 0.0012 18.6 0.8 0.0022 17.8 0.5 1.4 1 1 0 1 1 1 1 Sugar efflux transporter for intercellular exchange L51_S25_CI-B8 PF05047.11 OAP56752.1 - 7.9e-16 57.5 0.0 1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LigB PF02900.13 OAP56753.1 - 7.7e-52 175.9 0.3 8.6e-52 175.7 0.2 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PGA_cap PF09587.5 OAP56753.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap adh_short PF00106.20 OAP56754.1 - 2.7e-27 95.7 0.4 5.4e-27 94.7 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56754.1 - 8.5e-11 42.0 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP56754.1 - 1.5e-07 31.2 1.8 1.1e-06 28.4 1.3 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP56754.1 - 5.8e-06 26.4 0.2 1.1e-05 25.5 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP56754.1 - 0.0049 16.3 0.1 0.0088 15.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 OAP56754.1 - 0.0067 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain ODR4-like PF14778.1 OAP56754.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like DUF3237 PF11578.3 OAP56755.1 - 5.2e-36 123.2 0.0 7.7e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 OAP56755.1 - 3.7e-06 26.6 6.9 0.019 14.6 0.7 2.5 2 0 0 2 2 2 2 BED zinc finger Herpes_capsid PF06112.6 OAP56755.1 - 0.0079 16.2 2.6 0.016 15.2 1.1 1.8 2 0 0 2 2 2 1 Gammaherpesvirus capsid protein Abhydrolase_6 PF12697.2 OAP56757.1 - 2.7e-28 99.3 0.8 3.7e-28 98.9 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP56757.1 - 2.5e-07 30.5 0.0 5.3e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP56757.1 - 1e-05 25.2 0.0 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold SET PF00856.23 OAP56758.1 - 4.2e-20 72.6 0.0 1e-19 71.3 0.0 1.7 1 0 0 1 1 1 1 SET domain Gln-synt_C PF00120.19 OAP56759.1 - 7.9e-60 202.1 0.0 1e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 OAP56760.1 - 8.2e-26 90.8 0.3 1.1e-25 90.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP56760.1 - 1e-20 74.5 0.0 1.2e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP56760.1 - 1.4e-09 37.8 0.2 2e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP56760.1 - 0.00071 19.0 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAP56760.1 - 0.00079 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 OAP56760.1 - 0.0048 17.4 0.0 0.0097 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 OAP56760.1 - 0.019 13.7 0.0 0.18 10.4 0.0 2.1 1 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 OAP56760.1 - 0.05 12.5 0.1 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 OAP56760.1 - 0.1 12.6 0.6 0.29 11.1 0.4 1.9 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAP56760.1 - 0.13 12.0 1.3 0.26 11.0 0.2 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Proteasom_PSMB PF10508.4 OAP56762.1 - 5.5e-05 21.6 0.1 8.5e-05 21.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 OAP56762.1 - 0.054 13.7 0.6 0.27 11.5 0.4 2.2 1 1 0 1 1 1 0 HEAT repeats XPC-binding PF09280.6 OAP56762.1 - 0.95 8.9 4.7 2.2 7.8 0.6 2.6 2 0 0 2 2 2 0 XPC-binding domain JAB PF01398.16 OAP56763.1 - 1.3e-05 24.9 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3554 PF12074.3 OAP56765.1 - 6.1e-57 193.5 3.2 6.1e-57 193.5 2.2 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 OAP56765.1 - 2.7e-38 130.1 69.4 3.3e-10 40.1 0.0 17.4 10 5 8 18 18 18 10 HEAT repeats HEAT PF02985.17 OAP56765.1 - 3e-32 107.7 41.0 0.013 15.5 0.0 22.9 25 0 0 25 25 25 7 HEAT repeat HEAT_EZ PF13513.1 OAP56765.1 - 1.1e-30 105.3 55.5 1.6e-06 28.3 0.0 22.2 13 5 12 25 25 25 8 HEAT-like repeat Cnd1 PF12717.2 OAP56765.1 - 3.3e-13 49.8 1.2 0.78 9.5 0.0 9.2 8 3 2 10 10 9 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 OAP56765.1 - 1.8e-12 47.5 1.1 0.00017 21.5 0.0 6.7 5 2 1 6 6 6 2 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 OAP56765.1 - 9.7e-12 45.1 0.0 0.71 10.3 0.0 8.8 7 3 2 10 10 10 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAP56765.1 - 1.6e-11 44.0 0.0 0.35 10.1 0.0 7.0 5 2 2 8 8 8 5 CLASP N terminal Ipi1_N PF12333.3 OAP56765.1 - 1.5e-09 37.7 0.9 0.0002 21.3 0.1 6.2 6 1 0 6 6 5 1 Rix1 complex component involved in 60S ribosome maturation Cohesin_HEAT PF12765.2 OAP56765.1 - 8.2e-07 28.8 12.0 0.33 10.9 0.0 7.1 6 0 0 6 6 6 3 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 OAP56765.1 - 1.2e-06 27.1 5.9 0.25 9.6 0.3 6.8 6 2 0 6 6 6 2 Adaptin N terminal region Arm PF00514.18 OAP56765.1 - 0.026 14.3 9.1 33 4.5 0.0 8.1 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat AAA_10 PF12846.2 OAP56765.1 - 0.038 13.4 1.3 21 4.4 0.0 4.6 4 1 2 6 6 6 0 AAA-like domain Peptidase_M41 PF01434.13 OAP56766.1 - 2.6e-73 246.0 0.0 4.9e-73 245.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 OAP56766.1 - 2.3e-43 147.5 0.0 7e-43 145.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 OAP56766.1 - 1.8e-07 31.3 0.0 4.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 OAP56766.1 - 0.0003 20.5 0.0 0.0011 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAP56766.1 - 0.00078 19.5 0.1 0.22 11.6 0.1 3.1 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 OAP56766.1 - 0.0032 18.2 0.1 0.014 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAP56766.1 - 0.0069 15.4 0.1 0.037 13.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 OAP56766.1 - 0.0077 14.9 0.1 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 OAP56766.1 - 0.0098 15.9 0.6 0.13 12.2 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 OAP56766.1 - 0.022 14.4 3.1 0.023 14.4 0.5 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 OAP56766.1 - 0.025 14.4 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_pol PF00940.14 OAP56766.1 - 0.041 12.3 0.0 0.063 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase IstB_IS21 PF01695.12 OAP56766.1 - 0.059 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NCD2 PF04905.8 OAP56766.1 - 0.07 12.9 0.5 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) AAA_18 PF13238.1 OAP56766.1 - 0.09 13.0 0.1 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 OAP56766.1 - 0.26 10.3 0.0 0.26 10.3 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.1 OAP56766.1 - 0.28 10.5 3.5 0.25 10.7 0.3 2.4 2 1 1 3 3 3 0 AAA domain LRR_4 PF12799.2 OAP56768.1 - 0.048 13.2 1.8 1.7 8.3 1.1 3.3 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Pkinase PF00069.20 OAP56769.1 - 8.2e-56 189.0 0.1 4.9e-55 186.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56769.1 - 1.3e-28 99.8 0.0 8.1e-20 70.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 OAP56769.1 - 2.9e-06 27.7 0.1 8.7e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 OAP56769.1 - 0.00012 21.8 4.8 0.15 11.7 0.0 3.7 2 1 2 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.1 OAP56769.1 - 0.00016 20.7 0.2 0.0015 17.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like MmgE_PrpD PF03972.9 OAP56770.1 - 3e-147 490.3 0.0 3.5e-147 490.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family KNOX2 PF03791.8 OAP56770.1 - 0.051 12.8 0.1 0.14 11.4 0.1 1.7 1 0 0 1 1 1 0 KNOX2 domain Glyco_hydro_3 PF00933.16 OAP56771.1 - 1.5e-92 309.7 0.0 2.2e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAP56771.1 - 1.2e-51 175.4 0.1 2.4e-50 171.1 0.0 2.7 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 OAP56771.1 - 2.7e-21 75.2 0.1 5.4e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FMO-like PF00743.14 OAP56772.1 - 2.9e-15 55.4 0.1 4.9e-13 48.1 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAP56772.1 - 5.3e-15 56.0 0.0 1.1e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP56772.1 - 8.2e-09 35.3 0.0 3.6e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP56772.1 - 5.7e-06 25.4 1.9 1.8e-05 23.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAP56772.1 - 0.0024 16.8 0.0 0.22 10.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAC PF01849.13 OAP56774.1 - 7.9e-22 76.5 0.4 1.5e-21 75.6 0.3 1.5 1 0 0 1 1 1 1 NAC domain Abhydrolase_2 PF02230.11 OAP56775.1 - 5.2e-60 202.5 0.0 5.9e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 OAP56775.1 - 9.9e-12 44.8 0.0 1.6e-11 44.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP56775.1 - 1.8e-08 34.5 0.1 0.00013 21.9 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP56775.1 - 5.9e-06 25.6 1.1 6.1e-05 22.3 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 OAP56775.1 - 0.00021 20.8 0.0 0.0017 17.8 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 OAP56775.1 - 0.003 16.8 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF1581 PF07619.6 OAP56775.1 - 0.028 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) Abhydrolase_3 PF07859.8 OAP56775.1 - 0.082 12.4 0.0 5.5 6.5 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.17 OAP56775.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydro_lipase PF04083.11 OAP56775.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region EutQ PF06249.7 OAP56776.1 - 4.8e-10 39.1 0.0 6.4e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 OAP56776.1 - 1.4e-09 37.1 0.0 2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 OAP56776.1 - 8.7e-05 21.9 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 OAP56776.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 1 0 1 1 1 0 Cupin Fungal_trans_2 PF11951.3 OAP56777.1 - 4.1e-59 200.1 0.7 5.9e-59 199.5 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56777.1 - 2.9e-06 27.0 13.4 4.6e-06 26.4 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 OAP56778.1 - 2.1e-18 66.6 0.0 2.9e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP56778.1 - 6.9e-10 38.2 0.0 2.1e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 OAP56778.1 - 1.4e-09 37.1 0.0 2.5e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP56778.1 - 4.1e-06 26.9 0.0 9.8e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAP56778.1 - 0.013 15.1 0.2 0.036 13.7 0.1 1.6 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 OAP56778.1 - 0.013 15.4 2.5 0.018 14.9 0.3 2.3 2 1 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.8 OAP56778.1 - 0.036 13.3 0.0 1.8 7.7 0.0 2.5 3 0 0 3 3 3 0 NmrA-like family adh_short PF00106.20 OAP56779.1 - 1.1e-17 64.4 2.4 2.6e-16 59.9 1.7 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP56779.1 - 7.1e-10 38.8 0.2 1.2e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP56779.1 - 5.3e-07 29.3 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP56779.1 - 3.8e-05 22.7 0.0 0.00016 20.7 0.0 1.8 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 OAP56779.1 - 0.00027 20.7 0.1 0.00044 20.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 OAP56779.1 - 0.0011 19.0 0.0 0.0029 17.7 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 OAP56779.1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 OAP56779.1 - 0.034 13.1 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ctr PF04145.10 OAP56780.1 - 4.4e-33 114.3 0.1 5.2e-33 114.1 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Pyridox_oxase_2 PF12766.2 OAP56781.1 - 9.8e-26 89.9 0.0 1.7e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DAO PF01266.19 OAP56782.1 - 1.8e-43 148.8 0.0 2.1e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP56782.1 - 2.3e-08 33.9 0.1 0.0045 16.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP56782.1 - 4.2e-07 30.0 0.0 3.1e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP56782.1 - 2.2e-06 27.5 0.0 5.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 OAP56782.1 - 4.3e-05 22.3 0.1 0.00051 18.7 0.0 2.1 1 1 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 OAP56782.1 - 5.3e-05 22.2 0.1 0.00061 18.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.1 OAP56782.1 - 0.0052 15.7 0.0 0.2 10.5 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 OAP56782.1 - 0.0064 16.5 0.0 0.25 11.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP56782.1 - 0.013 14.4 0.3 0.038 12.8 0.2 1.7 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 OAP56782.1 - 0.023 13.1 0.0 0.11 10.8 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 OAP56782.1 - 0.029 14.7 0.0 0.25 11.7 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 OAP56783.1 - 4.8e-71 239.3 0.0 6.1e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP56783.1 - 5.8e-08 33.5 0.0 1.6e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.2 OAP56784.1 - 1.7e-53 178.8 5.7 5.9e-17 61.7 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 OAP56784.1 - 2.6e-44 146.8 13.7 2.7e-06 26.9 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 OAP56784.1 - 9.3e-42 140.6 17.4 1e-09 38.6 0.0 7.8 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP56784.1 - 1.2e-29 99.3 6.1 0.00059 19.8 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 OAP56784.1 - 6e-26 89.8 13.2 1e-06 28.7 0.0 7.4 1 1 5 7 7 7 6 Ankyrin repeats (many copies) PTE PF02126.13 OAP56784.1 - 0.1 11.6 0.2 0.95 8.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotriesterase family PEHE PF15275.1 OAP56784.1 - 0.23 11.9 3.1 0.4 11.1 1.1 2.1 2 0 0 2 2 2 0 PEHE domain Y_phosphatase2 PF03162.8 OAP56786.1 - 5.7e-39 133.1 0.0 9.3e-39 132.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 OAP56786.1 - 6.5e-08 32.9 0.0 1.7e-06 28.3 0.0 2.4 2 1 1 3 3 3 1 Tyrosine phosphatase family DSPc PF00782.15 OAP56786.1 - 0.0015 18.1 0.0 0.0029 17.1 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAP56786.1 - 0.052 12.8 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TatD_DNase PF01026.16 OAP56787.1 - 8e-50 169.4 0.0 1e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.13 OAP56788.1 - 3.7e-86 289.1 0.2 1.7e-85 286.9 0.1 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAP56788.1 - 2.8e-18 65.4 0.0 5.3e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAP56788.1 - 0.0001 21.3 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase PPR_3 PF13812.1 OAP56789.1 - 1.2e-12 47.0 4.5 0.00045 20.2 0.1 6.8 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 OAP56789.1 - 5e-10 39.1 0.3 0.017 15.1 0.0 4.9 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.15 OAP56789.1 - 1.4e-05 24.6 0.3 0.049 13.6 0.0 4.0 4 0 0 4 4 4 2 PPR repeat MRP-S25 PF13741.1 OAP56790.1 - 5.9e-74 248.4 0.6 7.3e-74 248.1 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Vfa1 PF08432.5 OAP56791.1 - 1.7e-58 197.6 13.5 2e-58 197.4 9.4 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 FLO_LFY PF01698.11 OAP56791.1 - 0.0098 14.7 4.6 0.012 14.4 3.2 1.1 1 0 0 1 1 1 1 Floricaula / Leafy protein U79_P34 PF03064.11 OAP56791.1 - 0.064 12.7 11.5 0.074 12.5 8.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF572 PF04502.8 OAP56791.1 - 0.064 12.4 14.0 0.083 12.0 9.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1510 PF07423.6 OAP56791.1 - 0.15 11.4 15.6 0.18 11.1 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 OAP56791.1 - 0.17 11.7 7.8 0.23 11.3 5.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 OAP56791.1 - 0.26 8.9 7.8 0.29 8.7 5.4 1.0 1 0 0 1 1 1 0 Ycf1 ETRAMP PF09716.5 OAP56791.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.2 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sporozoite_P67 PF05642.6 OAP56791.1 - 0.37 8.5 5.6 0.41 8.4 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 OAP56791.1 - 0.45 8.4 9.7 0.49 8.3 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 OAP56791.1 - 1.5 8.3 3.9 2.1 7.9 2.7 1.1 1 0 0 1 1 1 0 IncA protein FAM60A PF15396.1 OAP56791.1 - 1.9 8.1 11.3 0.38 10.4 5.6 1.5 2 0 0 2 2 2 0 Protein Family FAM60A FAM178 PF14816.1 OAP56791.1 - 1.9 7.1 5.3 2 7.0 3.7 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Peptidase_S49_N PF08496.5 OAP56791.1 - 2.2 8.0 11.6 3 7.6 8.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3987 PF13148.1 OAP56791.1 - 2.4 6.6 11.9 3.1 6.2 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RNA_polI_A34 PF08208.6 OAP56791.1 - 6.9 6.2 24.1 12 5.4 16.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TP53IP5 PF15331.1 OAP56791.1 - 7.6 6.3 10.1 11 5.9 7.0 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DSPc PF00782.15 OAP56792.1 - 2.8e-20 72.2 0.0 1.4e-08 34.4 0.1 3.3 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Mu-like_Com PF10122.4 OAP56792.1 - 0.018 14.0 0.4 0.046 12.7 0.3 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com Y_phosphatase PF00102.22 OAP56792.1 - 0.027 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-C2H2_4 PF13894.1 OAP56793.1 - 3.1e-06 27.1 20.3 0.028 14.7 1.8 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP56793.1 - 0.00015 21.9 22.1 0.011 16.0 1.3 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP56793.1 - 0.016 15.4 0.4 0.016 15.4 0.2 3.6 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAP56793.1 - 0.023 14.8 4.2 0.023 14.8 2.9 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 OAP56793.1 - 0.049 13.4 4.3 4 7.3 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-FCS PF06467.9 OAP56793.1 - 0.053 13.1 3.1 3.1 7.5 0.3 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-TFIIB PF13453.1 OAP56796.1 - 0.085 12.0 0.1 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger PWI PF01480.12 OAP56797.1 - 8e-30 102.7 0.0 2.1e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 PWI domain UPF0561 PF10573.4 OAP56797.1 - 0.53 10.1 8.3 1 9.2 5.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 LETM1 PF07766.8 OAP56798.1 - 8.7e-105 349.5 0.6 8.7e-105 349.5 0.4 1.8 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 OAP56798.1 - 1.4e-06 27.6 0.8 0.0013 18.2 0.0 3.9 4 0 0 4 4 4 2 SAP domain SMC_N PF02463.14 OAP56799.1 - 1.1e-55 188.2 0.0 5.3e-29 101.0 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAP56799.1 - 3.1e-32 111.0 0.0 1.4e-31 108.9 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAP56799.1 - 1.4e-12 48.1 10.1 2e-06 27.9 0.0 3.7 4 2 0 4 4 4 2 AAA domain AAA_29 PF13555.1 OAP56799.1 - 2.1e-09 36.7 0.0 4.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 OAP56799.1 - 4.6e-06 27.0 33.6 4.6e-06 27.0 23.3 6.1 2 2 1 3 3 2 2 AAA domain Spc7 PF08317.6 OAP56799.1 - 0.00074 18.2 14.7 0.00074 18.2 10.2 5.9 3 2 2 6 6 6 3 Spc7 kinetochore protein SbcCD_C PF13558.1 OAP56799.1 - 0.0014 18.5 0.0 0.0072 16.2 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit IncA PF04156.9 OAP56799.1 - 0.0022 17.6 24.2 0.0022 17.6 16.8 6.4 3 2 2 6 6 6 3 IncA protein Reo_sigmaC PF04582.7 OAP56799.1 - 0.042 13.0 24.8 0.16 11.0 0.9 4.8 4 2 1 6 6 6 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 OAP56799.1 - 0.81 9.9 0.0 0.81 9.9 0.0 6.0 4 2 0 4 4 3 0 ABC transporter Laminin_II PF06009.7 OAP56799.1 - 9.4 5.9 49.5 0.12 12.1 1.5 6.7 4 1 3 7 7 7 0 Laminin Domain II DUF2838 PF10998.3 OAP56800.1 - 5.8e-44 148.5 10.6 5.8e-44 148.5 7.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) DUF2130 PF09903.4 OAP56800.1 - 0.098 11.3 1.1 0.17 10.5 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Glyco_hydro_cc PF11790.3 OAP56802.1 - 1.5e-48 165.3 0.1 1.8e-48 165.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Hydrolase_6 PF13344.1 OAP56803.1 - 3e-30 104.0 0.0 5.1e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP56803.1 - 3e-13 50.6 0.0 5.2e-13 49.9 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP56803.1 - 2.4e-12 46.3 0.0 6.6e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 OAP56803.1 - 2.1e-05 24.7 0.0 0.0007 19.8 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.6 OAP56803.1 - 0.04 13.3 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Peptidase_M18 PF02127.10 OAP56804.1 - 5e-160 532.7 0.0 7.7e-160 532.0 0.0 1.3 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) WD40 PF00400.27 OAP56805.1 - 2.1e-33 112.9 6.7 1.4e-06 27.9 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 OAP56805.1 - 1e-06 28.6 0.1 0.022 14.4 0.0 3.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 OAP56805.1 - 0.085 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Biotin_lipoyl PF00364.17 OAP56806.1 - 4.9e-20 70.9 1.0 9.2e-20 70.0 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 OAP56806.1 - 1.1e-05 24.9 0.5 0.0005 19.6 0.0 3.1 2 1 1 3 3 3 1 Biotin-lipoyl like E3_binding PF02817.12 OAP56806.1 - 4.6e-05 22.9 0.0 0.00016 21.1 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain ADH_zinc_N PF00107.21 OAP56807.1 - 2.1e-06 27.3 0.5 4.1e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP56807.1 - 3e-06 26.9 0.0 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CtnDOT_TraJ PF07863.6 OAP56807.1 - 0.029 14.8 1.0 0.061 13.8 0.1 2.0 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon NAD_binding_10 PF13460.1 OAP56807.1 - 0.047 13.6 0.2 0.073 13.0 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding Tcp11 PF05794.8 OAP56808.1 - 1.1e-78 265.0 1.5 1.5e-78 264.5 1.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 ILVD_EDD PF00920.16 OAP56809.1 - 2e-153 511.5 0.0 2.4e-153 511.2 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Spermine_synth PF01564.12 OAP56810.1 - 2e-06 26.9 0.0 3.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_30 PF05430.6 OAP56810.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase RFX_DNA_binding PF02257.10 OAP56811.1 - 1.1e-28 99.1 0.1 2.6e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Herpes_ori_bp PF02399.10 OAP56811.1 - 0.21 9.5 0.0 0.4 8.5 0.0 1.4 1 0 0 1 1 1 0 Origin of replication binding protein TB2_DP1_HVA22 PF03134.14 OAP56812.1 - 2.6e-30 104.0 7.8 3.8e-30 103.4 5.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Peroxin-3 PF04882.7 OAP56813.1 - 2.7e-130 434.9 0.0 3.2e-130 434.7 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Glycos_transf_2 PF00535.21 OAP56814.1 - 1.3e-19 70.5 0.0 9.8e-11 41.6 0.0 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAP56814.1 - 9.6e-05 22.2 0.0 0.15 11.8 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 NUDIX PF00293.23 OAP56815.1 - 1.1e-15 57.4 0.1 1.3e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain HET PF06985.6 OAP56816.1 - 2.6e-36 124.8 0.1 4e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 OAP56817.1 - 3.1e-26 92.0 0.0 4.6e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56817.1 - 6.4e-05 22.1 0.0 0.29 10.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 OAP56817.1 - 0.041 13.6 0.1 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans PF04082.13 OAP56818.1 - 1.1e-19 70.3 3.1 1.5e-19 69.9 2.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP56818.1 - 0.00042 20.1 11.6 0.00081 19.2 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy PF03171.15 OAP56819.1 - 1e-19 70.6 0.0 1.8e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP56819.1 - 3.2e-16 59.9 0.6 8.5e-16 58.5 0.4 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ERF PF04404.7 OAP56819.1 - 0.009 15.5 0.1 0.02 14.4 0.0 1.5 1 1 0 1 1 1 1 ERF superfamily AA_permease PF00324.16 OAP56820.1 - 2.2e-107 359.3 38.6 2.8e-107 359.0 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP56820.1 - 5.5e-32 110.8 42.9 6.7e-32 110.5 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease 2OG-FeII_Oxy PF03171.15 OAP56821.1 - 2.2e-19 69.5 0.0 3.6e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP56821.1 - 1.6e-17 64.1 0.0 2.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal FAD_binding_3 PF01494.14 OAP56822.1 - 6.6e-73 245.7 0.1 8e-73 245.5 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP56822.1 - 4e-08 32.5 0.0 6.6e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.7 OAP56822.1 - 8.7e-07 28.7 0.0 7e-06 25.7 0.0 2.2 1 1 1 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 OAP56822.1 - 4.9e-06 26.4 0.2 1.5e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP56822.1 - 9.2e-06 24.9 0.1 1.7e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 OAP56822.1 - 0.00015 21.7 1.5 0.0008 19.3 0.5 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP56822.1 - 0.00017 20.1 0.7 0.012 14.1 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 OAP56822.1 - 0.00018 21.6 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP56822.1 - 0.00021 21.6 1.1 0.011 16.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP56822.1 - 0.00022 20.1 1.1 0.00039 19.3 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 OAP56822.1 - 0.00037 19.2 0.0 0.00063 18.4 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.2 OAP56822.1 - 0.009 15.1 3.1 0.039 13.0 2.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 OAP56822.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 OAP56822.1 - 0.035 14.3 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 OAP56822.1 - 0.036 12.9 0.4 0.067 12.1 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 OAP56822.1 - 0.11 11.3 0.1 0.28 10.0 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A LRRNT PF01462.13 OAP56823.1 - 1.1 8.8 7.4 0.41 10.1 2.1 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain SKG6 PF08693.5 OAP56825.1 - 0.037 13.3 0.2 0.18 11.1 0.1 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lysine_decarbox PF03641.9 OAP56826.1 - 8e-31 106.5 0.0 1.4e-30 105.8 0.0 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase DUF4169 PF13770.1 OAP56826.1 - 0.14 12.1 0.2 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) Proteasome PF00227.21 OAP56827.1 - 2.7e-50 170.3 0.1 3.3e-50 170.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAP56827.1 - 1.3e-11 43.5 0.3 1.3e-11 43.5 0.2 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 OAP56828.1 - 1.9e-42 143.7 7.9 2.1e-42 143.6 5.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Sre PF03125.13 OAP56828.1 - 4.6 6.0 6.8 0.9 8.3 1.6 1.8 2 0 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor UPF0220 PF05255.6 OAP56829.1 - 3.1e-69 231.4 5.2 3.4e-69 231.3 3.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Fes1 PF08609.5 OAP56830.1 - 1.6e-31 108.6 0.6 4.2e-29 100.8 0.2 2.3 2 0 0 2 2 2 2 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 OAP56830.1 - 3.9e-07 30.2 1.8 1.3e-06 28.5 0.3 2.3 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 OAP56830.1 - 2.5e-05 23.9 0.5 0.26 11.4 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 OAP56830.1 - 3e-05 24.3 2.3 0.0001 22.6 1.2 2.3 1 1 1 2 2 2 2 HEAT-like repeat Arm PF00514.18 OAP56830.1 - 0.0012 18.5 0.6 0.2 11.5 0.1 2.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 OAP56830.1 - 0.083 12.2 0.1 0.15 11.4 0.1 1.4 1 1 0 1 1 1 0 CLASP N terminal Adaptin_N PF01602.15 OAP56830.1 - 0.12 10.7 0.2 7.4 4.7 0.0 1.8 1 1 1 2 2 2 0 Adaptin N terminal region Actin PF00022.14 OAP56831.1 - 4.8e-159 528.9 0.0 5.5e-159 528.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 OAP56831.1 - 0.038 14.3 0.0 0.12 12.7 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GHMP_kinases_N PF00288.21 OAP56832.1 - 2.2e-13 50.0 0.0 4.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAP56832.1 - 0.00069 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal GARS_A PF01071.14 OAP56833.1 - 4.6e-82 274.3 0.1 3.4e-81 271.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 OAP56833.1 - 8.2e-36 122.4 0.1 2.7e-35 120.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 OAP56833.1 - 1.9e-33 115.6 0.0 5.2e-33 114.2 0.0 1.7 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 OAP56833.1 - 3e-27 94.6 0.1 6.5e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 OAP56833.1 - 1.7e-14 53.8 1.6 5.6e-14 52.1 1.1 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 OAP56833.1 - 8.9e-10 38.6 0.0 2.8e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAP56833.1 - 8.6e-07 28.0 0.0 2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 OAP56833.1 - 2.4e-05 23.7 0.0 4.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 OAP56833.1 - 5.1e-05 23.1 0.2 0.0003 20.6 0.0 2.3 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.6 OAP56833.1 - 0.0077 15.7 0.1 0.038 13.4 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain AP_endonuc_2 PF01261.19 OAP56833.1 - 0.014 14.6 0.1 1.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel CPSase_L_D2 PF02786.12 OAP56833.1 - 0.069 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain adh_short PF00106.20 OAP56834.1 - 1.5e-15 57.5 1.1 3.5e-15 56.3 0.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAP56834.1 - 4.1e-09 36.7 0.2 5.5e-09 36.2 0.2 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP56834.1 - 1.3e-08 34.5 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 OAP56834.1 - 1.2e-06 28.3 0.6 7.4e-06 25.7 0.4 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP56834.1 - 3.1e-05 23.8 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 OAP56834.1 - 0.098 12.6 0.5 0.36 10.8 0.2 2.0 2 0 0 2 2 2 0 TrkA-N domain Fil_haemagg PF05594.9 OAP56834.1 - 0.19 12.1 2.6 0.47 10.8 1.8 1.6 1 0 0 1 1 1 0 Haemagluttinin repeat Pet127 PF08634.5 OAP56835.1 - 1.7e-113 378.3 0.2 2.3e-113 377.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 FAM198 PF15051.1 OAP56835.1 - 0.2 10.3 0.0 0.74 8.4 0.0 1.8 2 0 0 2 2 2 0 FAM198 protein LRR_6 PF13516.1 OAP56836.1 - 0.17 12.0 3.8 3.8e+02 1.7 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 OAP56836.1 - 3.2 8.3 4.8 1.2e+02 3.6 0.0 5.5 6 0 0 6 6 6 0 Leucine rich repeat Gly_transf_sug PF04488.10 OAP56837.1 - 3.1e-20 72.4 0.0 5.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 OAP56837.1 - 0.063 11.7 6.5 0.35 9.2 0.4 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Mid2 PF04478.7 OAP56838.1 - 0.0004 19.8 0.3 0.0015 17.9 0.0 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor NCU-G1 PF15065.1 OAP56838.1 - 0.048 12.3 0.1 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Spt5_N PF11942.3 OAP56839.1 - 0.01 16.4 1.7 0.014 16.0 1.2 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-H PF05837.7 OAP56840.1 - 6.7 6.9 11.3 13 6.0 7.8 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Abhydrolase_6 PF12697.2 OAP56841.1 - 6.1e-13 49.1 0.3 1.1e-12 48.3 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP56841.1 - 2e-09 37.3 0.0 4.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP56841.1 - 2.2e-06 27.4 0.0 5.7e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 OAP56841.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase Peptidase_S9 PF00326.16 OAP56841.1 - 0.078 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Cohesin_load PF10345.4 OAP56842.1 - 6.8e-102 341.6 0.0 8.5e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.1 OAP56842.1 - 0.00019 21.3 4.7 0.36 10.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAP56842.1 - 0.0013 18.3 4.5 0.046 13.3 0.2 3.6 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 OAP56842.1 - 0.0031 18.1 0.6 2.4 8.9 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP56842.1 - 0.0092 15.8 0.4 5.5 7.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAP56842.1 - 0.067 12.8 0.9 11 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ndc1_Nup PF09531.5 OAP56842.1 - 0.42 8.9 3.9 0.65 8.3 2.7 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_14 PF13428.1 OAP56842.1 - 3.4 8.5 7.8 2.5 8.9 0.0 4.4 4 1 2 6 6 6 0 Tetratricopeptide repeat NIF PF03031.13 OAP56843.1 - 9.2e-19 67.6 0.0 1.6e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 OAP56844.1 - 3.6e-33 114.7 23.7 3.6e-33 114.7 16.4 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF947) ADH_N PF08240.7 OAP56845.1 - 6.4e-19 67.7 2.3 1.2e-18 66.8 1.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP56845.1 - 9e-12 44.6 0.4 3.1e-11 42.9 0.3 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 OAP56845.1 - 0.035 14.0 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase RNA_pol_L_2 PF13656.1 OAP56847.1 - 2.4e-28 97.3 0.0 3.6e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAP56847.1 - 6e-07 28.4 0.0 9.2e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2872 PF11071.3 OAP56847.1 - 0.055 13.3 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2872) Complex1_LYR PF05347.10 OAP56848.1 - 5.6e-08 32.4 0.4 1e-07 31.6 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 OAP56848.1 - 4.3e-07 30.3 1.2 5.1e-07 30.1 0.9 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 OAP56848.1 - 1.1e-06 28.7 0.2 1.7e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like IGPD PF00475.13 OAP56849.1 - 3.3e-56 189.1 0.2 1.6e-55 186.9 0.2 1.8 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF4507 PF14964.1 OAP56849.1 - 0.17 10.6 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) Histone PF00125.19 OAP56850.1 - 7.4e-29 99.6 0.4 1.5e-28 98.6 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAP56850.1 - 0.00021 21.4 0.1 0.00031 20.8 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAP56850.1 - 0.0056 15.9 0.1 0.0056 15.9 0.1 1.4 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 OAP56850.1 - 0.091 12.8 0.3 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DER1 PF04511.10 OAP56851.1 - 7e-49 166.0 2.2 8e-49 165.8 1.5 1.0 1 0 0 1 1 1 1 Der1-like family EF1G PF00647.14 OAP56852.1 - 1.4e-46 156.6 0.0 2.4e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 OAP56852.1 - 1e-09 38.3 0.7 1.6e-08 34.6 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAP56852.1 - 2.5e-09 37.2 0.1 1.3e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP56852.1 - 5.5e-09 35.9 2.9 5.9e-09 35.8 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAP56852.1 - 2.4e-07 30.5 0.1 8.9e-07 28.7 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP56852.1 - 8.4e-06 26.1 0.1 2.2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP56852.1 - 0.00037 20.4 0.1 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain PcfK PF14058.1 OAP56852.1 - 0.028 14.5 1.4 0.053 13.6 1.0 1.4 1 0 0 1 1 1 0 PcfK-like protein Ribosomal_S9 PF00380.14 OAP56853.1 - 1.3e-35 122.3 0.1 1.8e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Clr5 PF14420.1 OAP56855.1 - 1.9e-12 46.8 1.3 5.9e-12 45.3 0.9 1.9 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 OAP56855.1 - 0.0001 22.1 0.1 0.22 11.4 0.1 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAP56855.1 - 0.00024 20.7 0.0 2.9 8.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAP56855.1 - 0.044 13.4 0.0 18 5.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Erf4 PF10256.4 OAP56856.1 - 5.9e-30 103.5 0.0 1.2e-29 102.5 0.0 1.5 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family CFEM PF05730.6 OAP56857.1 - 4.7e-07 29.5 10.1 1.1e-06 28.3 7.0 1.7 1 0 0 1 1 1 1 CFEM domain Rep_fac_C PF08542.6 OAP56858.1 - 6.8e-20 70.8 0.0 1.4e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 OAP56858.1 - 5.9e-13 48.7 0.0 5.8e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 OAP56858.1 - 1.1e-10 41.8 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 OAP56858.1 - 5.2e-07 29.6 0.0 9.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 OAP56858.1 - 1.7e-06 26.9 0.0 0.034 12.8 0.0 3.0 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 OAP56858.1 - 6.8e-06 25.2 0.0 2e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAP56858.1 - 1.5e-05 25.1 0.1 0.00023 21.1 0.0 2.3 2 1 1 3 3 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 OAP56858.1 - 5.7e-05 22.7 0.0 8.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 OAP56858.1 - 6e-05 23.1 0.1 0.017 15.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 OAP56858.1 - 6.1e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 OAP56858.1 - 0.00064 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 OAP56858.1 - 0.0014 18.1 0.1 0.27 10.6 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 OAP56858.1 - 0.0042 16.8 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 OAP56858.1 - 0.0045 16.1 0.0 0.031 13.4 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 OAP56858.1 - 0.0056 15.4 0.1 0.013 14.2 0.0 1.6 1 1 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 OAP56858.1 - 0.0084 15.8 0.3 0.04 13.6 0.1 2.1 1 1 1 2 2 2 1 NTPase AAA_25 PF13481.1 OAP56858.1 - 0.0086 15.5 0.1 0.061 12.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAP56858.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 OAP56858.1 - 0.022 13.9 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_31 PF13614.1 OAP56858.1 - 0.038 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 OAP56858.1 - 0.041 13.3 0.2 0.59 9.6 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 OAP56858.1 - 0.051 13.8 0.1 0.12 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAP56858.1 - 0.052 13.1 0.0 0.086 12.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 OAP56858.1 - 0.08 11.7 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 OAP56858.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain HET PF06985.6 OAP56859.1 - 5.6e-36 123.7 0.2 9.7e-36 122.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.8 OAP56860.1 - 3.2e-17 62.5 0.0 4.6e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP56860.1 - 5.8e-12 45.9 0.0 9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP56860.1 - 0.00054 18.7 0.0 0.0059 15.3 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP56860.1 - 0.0054 16.1 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 OAP56860.1 - 0.013 15.1 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 KR domain TrkA_N PF02254.13 OAP56860.1 - 0.055 13.4 0.0 0.24 11.3 0.0 2.0 1 1 0 2 2 2 0 TrkA-N domain Synaphin PF05835.7 OAP56863.1 - 0.013 15.6 4.6 0.016 15.3 3.2 1.1 1 0 0 1 1 1 0 Synaphin protein DUF3987 PF13148.1 OAP56863.1 - 0.42 9.1 5.9 0.5 8.8 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4337 PF14235.1 OAP56863.1 - 3.7 7.3 5.7 4.8 6.9 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Toxin_47 PF15527.1 OAP56864.1 - 0.059 13.1 0.1 0.076 12.7 0.1 1.1 1 0 0 1 1 1 0 Putative toxin 47 NUDIX PF00293.23 OAP56865.1 - 9e-06 25.3 0.0 2.1e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Dysbindin PF04440.11 OAP56865.1 - 0.0095 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) Myc_N PF01056.13 OAP56865.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region tRNA-synt_1e PF01406.14 OAP56866.1 - 3.4e-111 371.1 0.2 5.1e-111 370.6 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 OAP56866.1 - 3.6e-06 25.8 0.6 0.01 14.5 0.1 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (M) HTH_16 PF12645.2 OAP56866.1 - 0.0099 15.7 0.5 0.028 14.3 0.3 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain tRNA-synt_1f PF01921.13 OAP56866.1 - 0.018 13.7 0.2 0.37 9.3 0.1 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (K) DALR_2 PF09190.6 OAP56866.1 - 0.035 14.3 0.0 0.035 14.3 0.0 2.2 2 0 0 2 2 2 0 DALR domain Arylsulfotran_2 PF14269.1 OAP56867.1 - 6.1e-57 193.0 0.9 1.1e-56 192.2 0.6 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAP56867.1 - 3.2e-19 68.8 0.0 7.8e-19 67.5 0.0 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) RTA1 PF04479.8 OAP56868.1 - 3.4e-48 164.0 10.8 3.4e-48 164.0 7.5 1.6 2 0 0 2 2 2 1 RTA1 like protein GCD14 PF08704.5 OAP56869.1 - 2e-59 201.0 8.5 5.7e-37 127.5 0.4 3.4 3 1 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit DUF2407 PF10302.4 OAP56869.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.8 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain Abhydrolase_4 PF08386.5 OAP56870.1 - 1.7e-18 66.4 0.0 3.3e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 OAP56870.1 - 6.4e-11 42.2 0.0 1.6e-06 27.8 0.0 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP56870.1 - 4.2e-07 30.0 0.0 2.6e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 OAP56871.1 - 1.2e-13 50.5 2.0 1.9e-13 49.9 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3669 PF12417.3 OAP56872.1 - 6.1e-20 70.7 0.0 1.3e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein Sugar_tr PF00083.19 OAP56873.1 - 1.6e-67 228.0 19.4 1.9e-67 227.7 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP56873.1 - 1.4e-16 60.2 19.7 1.4e-16 60.2 13.7 2.2 1 1 2 3 3 3 1 Major Facilitator Superfamily Hanta_G1 PF01567.11 OAP56873.1 - 0.033 12.4 0.0 0.05 11.8 0.0 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 DUF1680 PF07944.7 OAP56874.1 - 2.3e-121 405.6 0.0 2.8e-121 405.3 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_39 PF01229.12 OAP56875.1 - 0.0062 14.9 0.2 0.0085 14.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 DUF3192 PF11399.3 OAP56875.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Methyltransf_6 PF03737.10 OAP56876.1 - 2.2e-29 102.3 0.0 2.9e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase adh_short PF00106.20 OAP56877.1 - 6.7e-14 52.1 0.2 9.6e-14 51.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP56877.1 - 1.7e-07 31.0 0.1 2.6e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP56877.1 - 7.8e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAP56877.1 - 0.056 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ABM PF03992.11 OAP56879.1 - 2.2e-11 43.6 0.0 0.00017 21.5 0.0 3.1 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase Glyco_tranf_2_3 PF13641.1 OAP56880.1 - 3e-35 122.0 0.0 4.4e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAP56880.1 - 4.6e-16 59.1 0.8 4.6e-16 59.1 0.5 3.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 OAP56880.1 - 1.2e-11 44.5 0.0 2.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 OAP56880.1 - 1.1e-10 40.4 3.6 1.7e-07 29.9 1.7 2.5 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.1 OAP56880.1 - 2.3e-09 36.7 0.0 4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 OAP56880.1 - 0.0055 15.1 3.4 0.025 12.9 0.1 2.8 2 1 1 3 3 3 1 Chitin synthase Glyco_hydro_12 PF01670.11 OAP56881.1 - 2.6e-12 46.7 0.4 8.8e-12 45.0 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Aldedh PF00171.17 OAP56883.1 - 5.8e-148 493.0 0.0 6.7e-148 492.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP56883.1 - 0.00049 18.9 0.0 0.0027 16.5 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) HEAT_2 PF13646.1 OAP56884.1 - 3.9e-12 46.2 13.8 0.011 15.9 0.0 8.0 6 2 3 9 9 9 5 HEAT repeats HEAT PF02985.17 OAP56884.1 - 9.2e-12 44.0 12.2 12 6.2 0.0 10.6 9 0 0 9 9 9 5 HEAT repeat CLASP_N PF12348.3 OAP56884.1 - 4.1e-05 23.0 1.2 5.2 6.3 0.3 5.0 3 1 1 4 4 4 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 OAP56884.1 - 0.018 15.4 0.0 0.17 12.2 0.0 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 OAP56884.1 - 0.025 15.0 20.1 3.1 8.4 0.1 9.6 9 2 2 11 11 11 0 HEAT-like repeat DUF89 PF01937.14 OAP56885.1 - 2.3e-131 437.7 0.0 2.7e-131 437.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF3317 PF11779.3 OAP56886.1 - 5e-21 73.8 6.2 6.9e-21 73.4 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF1624 PF07786.7 OAP56886.1 - 0.013 14.8 0.3 0.015 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) DUF2346 PF09803.4 OAP56887.1 - 1.1e-06 28.4 3.5 3.4e-06 26.8 2.4 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) CDI PF02234.14 OAP56887.1 - 1.9 8.3 4.2 0.64 9.8 0.4 2.1 1 1 1 2 2 2 0 Cyclin-dependent kinase inhibitor MFS_1 PF07690.11 OAP56888.1 - 3.7e-46 157.4 12.4 5.5e-46 156.8 8.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP56888.1 - 7.7e-10 37.9 2.2 7.7e-10 37.9 1.5 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3017 PF11222.3 OAP56888.1 - 0.0053 16.5 0.5 0.034 13.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3017) MFS_1_like PF12832.2 OAP56888.1 - 0.1 12.4 4.9 0.61 9.9 0.2 3.5 3 0 0 3 3 3 0 MFS_1 like family DUF4131 PF13567.1 OAP56888.1 - 0.24 10.7 0.0 0.24 10.7 0.0 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) F-box PF00646.28 OAP56889.1 - 0.00067 19.2 3.4 0.00068 19.2 0.4 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 OAP56889.1 - 0.0088 15.7 0.4 0.019 14.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 OAP56889.1 - 0.057 13.1 1.2 0.12 12.0 0.8 1.7 1 1 0 1 1 1 0 F-box-like domain TPR_10 PF13374.1 OAP56890.1 - 4.5e-44 147.1 3.9 1.1e-14 53.7 0.0 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAP56890.1 - 7.3e-30 102.7 0.3 2e-14 53.2 0.1 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 OAP56890.1 - 2.9e-12 46.0 0.9 1.1e-11 44.1 0.6 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_7 PF13176.1 OAP56890.1 - 1.8e-11 42.9 4.9 0.015 15.0 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAP56890.1 - 5.2e-11 41.6 0.0 0.036 13.6 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 OAP56890.1 - 1.5e-08 33.9 0.0 2.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 OAP56890.1 - 1.7e-08 33.9 0.0 0.0055 16.3 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 OAP56890.1 - 1e-07 31.5 0.9 0.49 10.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAP56890.1 - 2.3e-07 31.3 0.8 0.00094 19.7 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP56890.1 - 6.7e-05 22.5 0.0 16 5.7 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAP56890.1 - 7.3e-05 22.8 0.0 7.9 7.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP56890.1 - 0.00066 20.0 2.8 15 6.5 0.0 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAP56890.1 - 0.0021 17.6 0.0 57 3.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAP56890.1 - 0.051 13.9 0.2 2.7 8.4 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat HMG_box_5 PF14887.1 OAP56890.1 - 0.064 13.0 0.9 0.32 10.8 0.0 2.6 3 0 0 3 3 3 0 HMG (high mobility group) box 5 TPR_21 PF09976.4 OAP56890.1 - 0.16 11.8 1.6 3.3 7.6 0.1 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAP56891.1 - 8.9e-90 292.4 17.2 7.7e-14 51.0 0.1 8.4 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 OAP56891.1 - 3.4e-64 212.7 5.2 4.5e-18 64.9 0.0 4.8 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 OAP56891.1 - 2e-32 109.4 4.1 0.0014 18.1 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 OAP56891.1 - 4.8e-30 100.9 10.9 0.0012 18.4 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 OAP56891.1 - 3.9e-29 100.1 17.8 4.4e-07 29.4 0.1 4.9 1 1 5 6 6 6 6 TPR repeat TPR_17 PF13431.1 OAP56891.1 - 1.3e-20 71.7 11.8 0.013 15.5 0.1 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 OAP56891.1 - 5.4e-19 66.5 4.5 0.067 13.1 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAP56891.1 - 9.7e-19 67.5 7.3 1.8e-05 25.2 0.1 5.7 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_4 PF07721.9 OAP56891.1 - 5.5e-18 63.4 4.7 0.53 10.8 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAP56891.1 - 8.8e-16 56.4 7.3 0.22 11.3 0.0 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAP56891.1 - 3.1e-13 49.0 10.7 0.82 10.4 0.0 7.4 6 1 1 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 OAP56891.1 - 5.3e-12 45.7 2.4 5.7e-05 23.1 0.1 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 OAP56891.1 - 2e-09 36.7 0.5 17 5.6 0.0 7.7 8 0 0 8 8 8 0 PPR repeat TPR_19 PF14559.1 OAP56891.1 - 1.1e-07 32.1 13.3 0.087 13.1 0.1 6.2 2 1 5 7 7 7 5 Tetratricopeptide repeat Ribosomal_S7 PF00177.16 OAP56891.1 - 1.1e-05 25.0 1.8 2.7 7.5 0.0 5.4 1 1 3 5 5 5 1 Ribosomal protein S7p/S5e PPR_3 PF13812.1 OAP56891.1 - 0.0001 22.2 2.2 51 4.5 0.0 7.0 8 0 0 8 8 7 0 Pentatricopeptide repeat domain TPR_3 PF07720.7 OAP56891.1 - 0.00011 21.8 19.1 6.7 6.6 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 OAP56891.1 - 0.00021 21.2 11.6 0.4 10.6 0.3 4.8 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAP56891.1 - 0.012 16.0 9.9 11 6.7 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat Rab5-bind PF09311.6 OAP56891.1 - 0.028 14.3 14.7 3 7.7 0.3 4.6 1 1 3 4 4 4 0 Rabaptin-like protein Radical_SAM_N PF08497.5 OAP56891.1 - 0.1 11.5 6.5 2.1 7.1 0.4 2.3 1 1 1 2 2 2 0 Radical SAM N-terminal DUF3366 PF11846.3 OAP56891.1 - 0.12 12.2 5.8 3.1 7.6 0.2 3.9 2 1 1 4 4 3 0 Domain of unknown function (DUF3366) DUF2959 PF11172.3 OAP56891.1 - 0.14 11.8 3.3 2.6 7.7 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2959) DUF1925 PF09094.6 OAP56891.1 - 0.26 11.3 10.4 64 3.6 0.1 5.6 3 1 3 6 6 5 0 Domain of unknown function (DUF1925) DUF4404 PF14357.1 OAP56891.1 - 0.83 10.1 5.1 53 4.3 0.1 4.0 2 1 3 5 5 5 0 Domain of unknown function (DUF4404) RNA_pol_Rpb1_5 PF04998.12 OAP56891.1 - 1.7 7.8 8.3 9.4 5.3 0.3 2.7 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 5 Death PF00531.17 OAP56891.1 - 3.3 7.5 6.9 31 4.4 0.0 4.8 7 0 0 7 7 6 0 Death domain Exo_endo_phos PF03372.18 OAP56893.1 - 7.5e-18 65.3 0.0 1.3e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 OAP56894.1 - 1.4e-06 27.9 0.2 0.0051 16.6 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Nbas_N PF15492.1 OAP56894.1 - 0.083 11.9 0.0 0.2 10.7 0.0 1.6 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal CAF1 PF04857.15 OAP56895.1 - 8e-61 205.6 0.0 1e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 OAP56896.1 - 2.5e-16 59.1 1.6 3.6e-16 58.6 1.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Cu_amine_oxid PF01179.15 OAP56897.1 - 5.3e-170 565.6 0.2 6.5e-170 565.3 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 OAP56897.1 - 4.1e-22 78.1 0.2 2.9e-21 75.4 0.0 2.2 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 OAP56897.1 - 3.2e-10 39.9 0.1 5.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.7 OAP56897.1 - 0.14 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC FAD_binding_1 PF00667.15 OAP56898.1 - 1.9e-34 119.0 0.0 2.8e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAP56898.1 - 6e-32 110.6 0.0 1.4e-31 109.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAP56898.1 - 1.8e-14 54.1 0.0 3.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 OAP56898.1 - 0.046 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_3 PF12641.2 OAP56898.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Collagen PF01391.13 OAP56899.1 - 0.001 18.5 25.6 0.001 18.5 17.8 3.0 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Ribosomal_S15 PF00312.17 OAP56899.1 - 0.0057 16.3 0.3 0.01 15.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Tho2 PF11262.3 OAP56899.1 - 0.27 10.2 1.3 0.37 9.7 0.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Glypican PF01153.14 OAP56899.1 - 2.3 6.7 4.5 5 5.6 3.2 1.7 1 1 0 1 1 1 0 Glypican Abhydrolase_5 PF12695.2 OAP56900.1 - 0.00062 19.5 0.0 0.00098 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP56900.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP56900.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Zn_clus PF00172.13 OAP56901.1 - 1.4e-08 34.4 7.9 2.6e-08 33.6 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP56901.1 - 5.7e-05 21.8 1.3 8e-05 21.4 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.1 OAP56902.1 - 0.079 12.7 0.7 0.2 11.5 0.5 1.7 1 0 0 1 1 1 0 Ring finger domain Aminotran_5 PF00266.14 OAP56903.1 - 8.9e-27 93.7 0.0 8.6e-19 67.5 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class-V RNA_pol_3_Rpc31 PF11705.3 OAP56904.1 - 2.3e-28 99.7 71.1 2.7e-26 92.9 0.1 3.0 2 1 1 3 3 3 2 DNA-directed RNA polymerase III subunit Rpc31 TIMELESS_C PF05029.8 OAP56904.1 - 0.24 10.2 30.0 0.4 9.5 20.8 1.3 1 0 0 1 1 1 0 Timeless protein C terminal region MA-Mit PF09245.5 OAP56905.1 - 0.0029 16.9 0.1 0.0043 16.3 0.1 1.3 1 0 0 1 1 1 1 Mycoplasma arthritidis-derived mitogen AMP-binding PF00501.23 OAP56906.1 - 3.1e-76 256.4 0.0 4e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP56906.1 - 1.6e-15 57.8 0.7 4.4e-15 56.3 0.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WSC PF01822.14 OAP56907.1 - 3.6e-09 36.4 14.8 8.8e-09 35.1 10.2 1.7 1 0 0 1 1 1 1 WSC domain Podoplanin PF05808.6 OAP56907.1 - 9.8e-05 21.9 2.4 0.00016 21.2 1.7 1.2 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.2 OAP56907.1 - 0.0028 16.9 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity NfeD PF01957.13 OAP56909.1 - 0.61 10.2 0.1 0.61 10.2 0.0 3.1 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding FAD_binding_4 PF01565.18 OAP56910.1 - 2.2e-25 88.7 1.0 4.7e-25 87.6 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAP56910.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Exo_endo_phos PF03372.18 OAP56911.1 - 3.1e-17 63.3 0.1 5.4e-17 62.5 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fungal_trans PF04082.13 OAP56914.1 - 3e-13 49.2 2.0 2.8e-12 46.0 0.2 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP56914.1 - 8.7e-12 44.6 7.1 2e-05 24.6 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP56914.1 - 1.7e-09 37.3 9.2 0.00013 22.0 2.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP56914.1 - 1e-08 35.0 2.7 1e-08 35.0 1.9 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAP56914.1 - 0.00039 20.4 0.4 1.2 9.3 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 OAP56914.1 - 0.0012 18.8 3.9 0.0027 17.7 2.7 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 OAP56914.1 - 0.018 14.8 2.9 0.53 10.2 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 OAP56914.1 - 0.032 13.8 3.7 0.35 10.5 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.2 OAP56914.1 - 0.045 13.9 1.3 12 6.2 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Lyase_1 PF00206.15 OAP56915.1 - 1.5e-113 379.1 0.0 2.2e-113 378.5 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 OAP56915.1 - 3e-22 78.4 0.0 7.3e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Antimicrobial_2 PF08023.7 OAP56915.1 - 0.12 12.6 3.3 1.6 9.1 0.0 3.4 3 0 0 3 3 3 0 Frog antimicrobial peptide Pyr_redox_2 PF07992.9 OAP56916.1 - 1.4e-10 41.3 5.2 1.4e-05 25.0 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP56916.1 - 9e-09 35.6 3.8 3.6e-07 30.4 1.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP56916.1 - 0.00047 19.9 3.5 4 7.1 0.0 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 OAP56916.1 - 0.023 13.3 3.2 0.94 8.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase COX7B PF05392.6 OAP56916.1 - 0.029 13.9 0.1 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB Pyr_redox_3 PF13738.1 OAP56916.1 - 0.029 14.4 1.5 0.82 9.6 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP56916.1 - 3.6 6.4 4.6 33 3.2 0.0 3.1 3 1 1 4 4 4 0 Lycopene cyclase protein SET PF00856.23 OAP56918.1 - 1.3e-09 38.5 0.0 2.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 SET domain TRI12 PF06609.8 OAP56919.1 - 4.2e-33 114.4 28.6 5.5e-33 114.0 19.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP56919.1 - 9.2e-22 77.2 49.2 9.2e-22 77.2 34.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP56919.1 - 6.7e-09 34.8 19.3 6.7e-09 34.8 13.4 3.1 1 1 0 2 2 2 2 Sugar (and other) transporter Ribosomal_S30 PF04758.9 OAP56921.1 - 4.6e-30 103.1 9.0 4.9e-30 103.0 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 UCH PF00443.24 OAP56922.1 - 4.8e-52 176.7 0.0 5.9e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAP56922.1 - 5.1e-16 58.9 0.7 6.2e-15 55.4 0.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 OAP56922.1 - 3.9e-08 32.5 0.3 1.3e-07 30.9 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family ARPC4 PF05856.7 OAP56923.1 - 6.8e-75 250.1 3.7 7.5e-75 249.9 2.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Zn_clus PF00172.13 OAP56925.1 - 6.2e-08 32.4 7.6 9.1e-08 31.8 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.5 OAP56926.1 - 1.1e-72 243.9 0.0 1.4e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CDC45 PF02724.9 OAP56926.1 - 0.087 10.8 6.2 0.13 10.3 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAP56926.1 - 1.2 6.9 13.5 1.7 6.4 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family ORC6 PF05460.8 OAP56926.1 - 8.3 5.3 10.9 13 4.7 7.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Methyltransf_23 PF13489.1 OAP56927.1 - 4.4e-15 55.7 0.0 8.4e-15 54.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP56927.1 - 3.8e-12 46.0 0.0 2.1e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 OAP56927.1 - 4.6e-11 43.0 0.0 2.5e-09 37.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP56927.1 - 2.5e-10 40.9 0.0 4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP56927.1 - 2.1e-09 37.7 0.0 7.4e-08 32.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP56927.1 - 6e-09 36.1 0.0 3.9e-08 33.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP56927.1 - 9e-08 31.5 0.0 0.0059 15.7 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 OAP56927.1 - 1.5e-05 25.0 0.1 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 OAP56927.1 - 0.001 18.5 0.0 0.0023 17.4 0.0 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.15 OAP56927.1 - 0.006 15.6 0.0 0.01 14.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase N6_N4_Mtase PF01555.13 OAP56927.1 - 0.053 12.9 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Innate_immun PF12782.2 OAP56927.1 - 8.5 5.5 12.8 12 5.0 8.9 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family TYW3 PF02676.9 OAP56928.1 - 5.6e-51 172.5 0.0 2.2e-50 170.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase TYW3 HAD PF12710.2 OAP56929.1 - 3.7e-10 40.2 0.1 5.7e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 OAP56929.1 - 0.002 17.3 0.0 0.008 15.3 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 OAP56929.1 - 0.0071 15.6 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 OAP56929.1 - 0.014 15.8 0.1 0.24 11.7 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Acyl-CoA_dh_1 PF00441.19 OAP56931.1 - 1.3e-41 142.2 0.3 2.2e-41 141.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAP56931.1 - 1.4e-30 106.1 0.1 3e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAP56931.1 - 2.4e-20 71.7 0.2 4.4e-20 70.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAP56931.1 - 8.9e-15 55.1 0.0 1.9e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 OAP56931.1 - 0.00011 21.7 1.4 0.00045 19.7 0.5 2.2 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Oxidored_FMN PF00724.15 OAP56931.1 - 0.071 12.0 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family IMS PF00817.15 OAP56932.1 - 7e-40 136.2 0.0 1.2e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAP56932.1 - 3.3e-14 52.9 0.0 5.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 OAP56932.1 - 0.011 15.6 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif DUF2197 PF09963.4 OAP56932.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-B_box PF00643.19 OAP56932.1 - 0.14 12.0 0.7 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 B-box zinc finger Metal_resist PF13801.1 OAP56933.1 - 0.35 10.8 5.5 20 5.1 3.8 2.8 1 1 0 1 1 1 0 Heavy-metal resistance OmpH PF03938.9 OAP56933.1 - 1.8 8.5 14.3 3 7.7 9.9 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Fungal_trans PF04082.13 OAP56934.1 - 1.5e-33 115.7 1.5 3.1e-33 114.7 1.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 OAP56935.1 - 1.1e-73 247.9 0.0 2.6e-73 246.8 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP56935.1 - 5.1e-12 46.5 0.1 2.2e-11 44.5 0.1 2.2 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain MUG113 PF13455.1 OAP56937.1 - 3.7e-29 100.9 0.1 8.4e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 OAP56937.1 - 7e-20 71.2 2.0 3.9e-19 68.8 1.4 2.2 1 1 0 1 1 1 1 T5orf172 domain Glyco_transf_28 PF03033.15 OAP56938.1 - 1.7e-20 73.2 0.0 4e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 OAP56938.1 - 2.7e-06 26.2 0.0 4.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 OAP56938.1 - 0.0076 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PhyH PF05721.8 OAP56939.1 - 1.6e-24 87.1 0.0 2.2e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Striatin PF08232.7 OAP56940.1 - 0.00072 19.8 1.7 0.00072 19.8 1.2 2.1 2 0 0 2 2 2 1 Striatin family BBP1_C PF15272.1 OAP56940.1 - 0.019 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF3987 PF13148.1 OAP56940.1 - 2.8 6.4 5.0 0.36 9.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Fungal_trans_2 PF11951.3 OAP56941.1 - 0.00014 20.6 0.1 0.00021 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 OAP56942.1 - 3.3e-37 128.0 0.0 4.1e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 OAP56943.1 - 4e-56 190.3 0.0 5.6e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP56943.1 - 6.5e-36 123.7 0.0 1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAP56943.1 - 5.3e-06 25.5 0.6 0.0014 17.5 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP56943.1 - 0.00026 20.0 0.0 0.00041 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP56943.1 - 0.00053 19.0 0.3 0.00084 18.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP56943.1 - 0.001 19.0 1.7 0.0016 18.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP56943.1 - 0.035 13.9 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP56943.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 OAP56943.1 - 0.14 11.0 0.7 0.38 9.5 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 OAP56943.1 - 0.16 10.3 0.3 0.23 9.9 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 OAP56943.1 - 0.17 10.4 0.1 0.3 9.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HlyIII PF03006.15 OAP56944.1 - 4.5e-11 42.5 3.3 5.2e-11 42.3 2.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DJ-1_PfpI PF01965.19 OAP56945.1 - 6.6e-22 77.5 0.1 1.1e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 OAP56945.1 - 3.8e-17 61.5 0.3 7.1e-17 60.6 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Peptidase_C26 PF07722.8 OAP56945.1 - 0.087 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C26 Fungal_trans PF04082.13 OAP56946.1 - 3.6e-27 94.8 0.1 5.5e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 OAP56947.1 - 5.5e-181 601.9 0.2 6.2e-181 601.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TAXi_C PF14541.1 OAP56947.1 - 0.14 11.7 0.1 6.5 6.2 0.0 2.7 2 1 1 3 3 3 0 Xylanase inhibitor C-terminal RRM_1 PF00076.17 OAP56949.1 - 1e-32 111.5 0.3 1.4e-16 59.8 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP56949.1 - 7.9e-24 83.4 0.0 2.2e-12 46.7 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP56949.1 - 5.9e-11 42.0 0.0 7.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 OAP56949.1 - 0.00092 18.8 0.4 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 DbpA RNA binding domain API5 PF05918.6 OAP56949.1 - 0.0076 14.8 3.2 0.01 14.3 2.2 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Limkain-b1 PF11608.3 OAP56949.1 - 0.046 13.4 0.6 13 5.5 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 FXR1P_C PF12235.3 OAP56949.1 - 1.6 8.8 13.4 2.6 8.1 8.8 1.8 1 1 0 1 1 1 0 Fragile X-related 1 protein C terminal MARVEL PF01284.18 OAP56950.1 - 6.3e-11 42.2 6.8 8.7e-11 41.8 4.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain SH3_1 PF00018.23 OAP56951.1 - 1.5e-09 37.0 0.7 3.4e-09 35.9 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 OAP56951.1 - 3.8e-07 29.5 0.0 6.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAP56951.1 - 1.5e-06 27.5 0.0 2.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain YhhN PF07947.9 OAP56951.1 - 0.0058 16.0 12.5 0.0082 15.5 8.7 1.2 1 0 0 1 1 1 1 YhhN-like protein Sulfate_transp PF00916.15 OAP56951.1 - 0.019 13.9 3.4 0.026 13.5 2.4 1.1 1 0 0 1 1 1 0 Sulfate transporter family TMEM220 PF15071.1 OAP56951.1 - 0.041 14.3 3.8 0.062 13.7 2.3 1.5 1 1 0 1 1 1 0 Transmembrane family 220, helix Dispanin PF04505.7 OAP56951.1 - 0.099 12.1 3.2 0.13 11.8 0.7 2.3 2 0 0 2 2 2 0 Interferon-induced transmembrane protein DUF2569 PF10754.4 OAP56951.1 - 0.39 10.9 6.6 0.18 11.9 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF1129 PF06570.6 OAP56951.1 - 1.8 7.8 10.0 0.097 11.9 3.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) TetR_C_7 PF14246.1 OAP56952.1 - 0.076 13.2 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal region DivIC PF04977.10 OAP56952.1 - 3 7.4 5.0 0.39 10.2 0.5 1.7 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 OAP56952.1 - 4 6.9 6.7 19 4.7 4.1 2.1 1 1 1 2 2 2 0 IncA protein Bot1p PF12298.3 OAP56954.1 - 1.6e-15 57.4 0.3 1.6e-15 57.4 0.2 2.7 2 1 1 3 3 3 1 Eukaryotic mitochondrial regulator protein NTPase_P4 PF11602.3 OAP56954.1 - 0.037 13.0 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Glyco_hydro_43 PF04616.9 OAP56955.1 - 6.2e-25 87.8 0.0 8.2e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 OAP56956.1 - 8.3e-35 120.1 20.6 8.3e-35 120.1 14.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily YfhO PF09586.5 OAP56956.1 - 0.031 12.3 0.7 0.15 10.0 0.6 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF3169 PF11368.3 OAP56956.1 - 0.031 13.4 0.2 0.3 10.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) Deltaretro_Tax PF05599.6 OAP56956.1 - 0.066 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein DUF4064 PF13273.1 OAP56956.1 - 3.3 7.8 10.2 7.5 6.7 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) GFO_IDH_MocA PF01408.17 OAP56957.1 - 1e-25 90.6 0.0 1.6e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP56957.1 - 4.4e-08 32.9 0.1 1.7e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 OAP56957.1 - 3.4e-06 27.4 0.2 5.8e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 OAP56957.1 - 0.0018 18.5 0.0 0.0028 17.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 OAP56957.1 - 0.0033 17.3 0.1 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 OAP56957.1 - 0.061 12.2 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Redoxin PF08534.5 OAP56957.1 - 0.084 12.4 0.1 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Redoxin ADH_zinc_N PF00107.21 OAP56957.1 - 0.095 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Zwint PF15556.1 OAP56958.1 - 0.081 12.1 3.3 0.11 11.6 2.3 1.2 1 0 0 1 1 1 0 ZW10 interactor PNP_UDP_1 PF01048.15 OAP56959.1 - 2.1e-08 33.4 2.5 8.3e-08 31.4 1.7 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 OAP56960.1 - 9.3e-44 147.6 9.4 3.2e-17 62.6 0.2 4.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 OAP56960.1 - 2.4e-40 134.3 24.2 3.9e-06 26.3 0.1 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 OAP56960.1 - 4.7e-29 100.2 6.6 7.7e-06 26.2 0.0 7.1 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP56960.1 - 3.1e-23 81.2 11.4 9.6e-06 25.6 0.2 5.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP56960.1 - 5.1e-21 72.6 7.4 0.056 13.6 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat NACHT PF05729.7 OAP56960.1 - 1.2e-07 31.5 0.1 2.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP56960.1 - 3.6e-06 27.0 5.4 4.1e-06 26.9 0.0 3.3 3 2 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.9 OAP56960.1 - 0.00088 18.3 0.7 0.48 9.3 0.0 2.6 2 1 1 3 3 3 2 KAP family P-loop domain AAA_22 PF13401.1 OAP56960.1 - 0.00098 19.2 0.0 0.0039 17.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 OAP56960.1 - 0.0022 18.2 0.0 0.072 13.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 OAP56960.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 OAP56960.1 - 0.022 14.9 0.0 0.066 13.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ApoLp-III PF07464.6 OAP56960.1 - 0.031 14.2 0.4 10 6.1 0.0 3.8 1 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) AAA_17 PF13207.1 OAP56960.1 - 0.18 12.6 1.3 0.66 10.8 0.5 2.4 2 1 0 2 2 2 0 AAA domain TPR_12 PF13424.1 OAP56961.1 - 7.7e-17 61.0 8.2 8.6e-08 32.0 0.1 4.1 1 1 3 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 OAP56961.1 - 3e-14 52.5 0.0 6.3e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 OAP56961.1 - 2.8e-08 33.2 8.8 4.1e-06 26.3 1.2 3.6 2 1 1 3 3 3 2 TPR repeat AAA_16 PF13191.1 OAP56961.1 - 2.8e-06 27.4 0.1 1.4e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 OAP56961.1 - 3.7e-06 26.8 0.0 8.5e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase TPR_1 PF00515.23 OAP56961.1 - 8.3e-05 22.0 15.5 0.78 9.4 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAP56961.1 - 0.00018 21.2 11.1 1.1 9.4 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 OAP56961.1 - 0.00053 20.1 0.0 0.0019 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 OAP56961.1 - 0.0059 17.2 3.7 0.36 11.5 0.1 3.7 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAP56961.1 - 0.045 13.7 0.1 0.045 13.7 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat AAA_14 PF13173.1 OAP56961.1 - 0.078 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 OAP56961.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TPR_8 PF13181.1 OAP56961.1 - 0.13 12.1 7.0 63 3.6 0.0 5.5 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP56961.1 - 0.27 11.9 11.1 1.3e+02 3.6 0.1 6.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP56961.1 - 2 8.4 8.6 1.8 8.5 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 OAP56961.1 - 3.1 8.0 8.2 0.73 10.0 0.2 3.7 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 APH PF01636.18 OAP56962.1 - 1.2e-07 31.6 0.8 0.013 15.2 0.1 3.0 2 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP56962.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 OAP56962.1 - 0.0026 16.9 0.0 0.74 8.8 0.0 3.0 3 0 0 3 3 3 1 Ecdysteroid kinase DUF1463 PF07316.6 OAP56962.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) DUF3215 PF11503.3 OAP56963.1 - 0.04 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) DUF3398 PF11878.3 OAP56963.1 - 0.051 13.4 0.1 6.4 6.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3398) DAO PF01266.19 OAP56964.1 - 2e-07 30.2 0.0 9.6e-07 28.0 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase PQQ_3 PF13570.1 OAP56964.1 - 0.078 13.2 0.4 0.2 12.0 0.3 1.7 1 0 0 1 1 1 0 PQQ-like domain MFS_1 PF07690.11 OAP56965.1 - 2.1e-22 79.3 24.0 3.4e-22 78.6 16.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 OAP56965.1 - 0.033 12.9 11.4 0.16 10.6 7.9 1.8 1 1 0 1 1 1 0 PUCC protein DUF3236 PF11576.3 OAP56965.1 - 0.088 12.2 0.5 0.16 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) PAP_assoc PF03828.14 OAP56966.1 - 7e-18 64.3 0.2 2.3e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 OAP56966.1 - 4.2e-07 30.2 0.0 7.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain SE PF08491.5 OAP56967.1 - 4.9e-104 347.0 0.0 6.8e-104 346.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 OAP56967.1 - 1.5e-11 43.9 0.0 1.3e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP56967.1 - 2.2e-09 36.7 0.3 5.9e-08 31.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP56967.1 - 1.8e-05 24.6 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP56967.1 - 3.9e-05 22.6 1.7 0.00044 19.2 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 OAP56967.1 - 0.00032 20.6 0.4 0.00091 19.2 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 OAP56967.1 - 0.00071 19.2 0.1 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 OAP56967.1 - 0.0008 18.3 0.1 0.018 13.9 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 OAP56967.1 - 0.0012 17.9 0.1 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 OAP56967.1 - 0.0014 17.6 0.5 0.035 13.0 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.11 OAP56967.1 - 0.0023 17.3 0.1 0.0046 16.4 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 OAP56967.1 - 0.0054 17.1 0.2 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 OAP56967.1 - 0.01 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 OAP56967.1 - 0.017 14.1 1.9 0.022 13.8 1.2 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAP56967.1 - 0.037 13.7 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 OAP56967.1 - 0.057 11.8 0.2 0.081 11.3 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.16 OAP56967.1 - 0.077 12.8 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 OAP56967.1 - 0.12 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 OAP56967.1 - 0.12 10.9 0.1 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Ldh_1_N PF00056.18 OAP56967.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Lactamase_B PF00753.22 OAP56968.1 - 9.4e-19 67.8 2.4 1.8e-18 66.9 1.7 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP56968.1 - 1.8e-07 30.9 0.2 2.4e-07 30.4 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP56968.1 - 0.073 12.7 0.4 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DIOX_N PF14226.1 OAP56969.1 - 4.4e-23 82.0 1.5 1.3e-22 80.5 1.0 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP56969.1 - 2e-16 60.0 0.0 4.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_polI_A34 PF08208.6 OAP56969.1 - 0.15 11.7 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2439 PF10382.4 OAP56970.1 - 2.3e-24 85.4 0.1 3.6e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Viral_cys_rich PF08008.7 OAP56970.1 - 0.086 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Viral cysteine rich SH3_9 PF14604.1 OAP56971.1 - 2.7e-15 55.6 0.1 6.3e-15 54.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAP56971.1 - 6.5e-14 51.0 0.1 1.2e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 OAP56971.1 - 6.9e-13 48.6 3.1 6.9e-13 48.6 2.1 1.4 2 0 0 2 2 2 1 BAR domain SH3_2 PF07653.12 OAP56971.1 - 6.6e-11 41.5 0.0 1.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ABC_tran PF00005.22 OAP56972.1 - 7.3e-15 55.4 0.2 1.7e-13 51.0 0.2 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAP56972.1 - 4.3e-10 40.0 0.1 0.00029 20.9 0.1 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP56972.1 - 0.00047 19.6 0.1 0.0009 18.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 OAP56972.1 - 0.0013 16.2 0.4 0.0016 15.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PduV-EutP PF10662.4 OAP56972.1 - 0.0042 16.5 0.1 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 OAP56972.1 - 0.0075 16.6 0.1 0.011 16.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAP56972.1 - 0.021 14.2 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 OAP56972.1 - 0.036 13.2 0.0 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 OAP56972.1 - 0.048 13.6 0.2 0.084 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 OAP56972.1 - 0.056 12.4 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 OAP56972.1 - 0.061 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRP54 PF00448.17 OAP56972.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 OAP56972.1 - 0.067 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 OAP56972.1 - 0.076 13.8 0.4 0.16 12.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 OAP56972.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 1 1 2 2 2 0 AAA domain Arf PF00025.16 OAP56972.1 - 0.16 11.1 0.1 0.37 10.0 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_5 PF07728.9 OAP56972.1 - 0.19 11.4 0.6 1.6 8.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 OAP56972.1 - 0.19 10.1 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 OAP56973.1 - 1e-59 196.3 23.3 1.6e-09 37.2 0.0 11.4 12 0 0 12 12 12 9 WD domain, G-beta repeat RTA1 PF04479.8 OAP56974.1 - 6e-35 120.7 4.2 7.1e-35 120.5 2.9 1.0 1 0 0 1 1 1 1 RTA1 like protein Aph-1 PF06105.7 OAP56974.1 - 0.04 13.1 0.2 0.04 13.1 0.1 2.2 1 1 1 2 2 2 0 Aph-1 protein Urm1 PF09138.6 OAP56976.1 - 2.3e-33 114.1 0.0 2.6e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 OAP56976.1 - 0.056 13.8 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.13 OAP56977.1 - 3.3e-61 206.1 0.0 5e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 OAP56977.1 - 1.4e-22 80.4 0.7 2.2e-22 79.8 0.5 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 OAP56977.1 - 0.00026 21.8 0.3 0.0045 17.7 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 OAP56977.1 - 0.016 15.0 0.0 0.055 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Porin_3 PF01459.17 OAP56978.1 - 2e-74 250.3 0.0 2.3e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 OAP56978.1 - 0.0028 16.9 0.0 0.0076 15.6 0.0 1.7 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 OAP56979.1 - 1.9e-62 210.7 0.0 2.3e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP56979.1 - 3.9e-25 88.4 0.0 5e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP56979.1 - 1.4e-07 30.7 0.0 9.2e-07 28.1 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 OAP56979.1 - 0.00058 19.6 0.1 0.0071 16.1 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP56979.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 OAP56980.1 - 5.5e-82 273.8 0.0 8.6e-82 273.2 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 OAP56980.1 - 3.9e-55 186.8 0.1 5.4e-55 186.3 0.1 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 OAP56980.1 - 2.9e-06 26.8 0.0 9.3e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 MIF4G domain DUF4398 PF14346.1 OAP56981.1 - 0.079 13.0 7.1 0.072 13.1 3.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) RRM_1 PF00076.17 OAP56982.1 - 4.8e-37 125.4 0.0 1.2e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP56982.1 - 1.8e-20 72.6 0.1 9.4e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP56982.1 - 1.2e-16 60.3 0.1 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 OAP56982.1 - 0.016 14.7 0.1 7 6.2 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 OAP56982.1 - 0.017 14.8 0.4 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Tom7 PF08038.7 OAP56983.1 - 1.1e-13 50.3 0.0 1.2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 TOM7 family Sigma70_r4 PF04545.11 OAP56983.1 - 0.1 11.9 0.1 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 WD40 PF00400.27 OAP56984.1 - 2.4e-71 233.2 9.6 2.1e-11 43.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 OAP56984.1 - 1.1e-24 86.3 10.9 1.8e-24 85.6 7.6 1.3 1 0 0 1 1 1 1 Tup N-terminal Nbas_N PF15492.1 OAP56984.1 - 2.3e-05 23.6 0.1 0.04 13.0 0.0 2.9 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 OAP56984.1 - 6.6e-05 21.8 0.0 0.12 11.1 0.0 3.4 1 1 2 3 3 3 3 Nup133 N terminal like eIF2A PF08662.6 OAP56984.1 - 0.00016 21.4 0.0 0.053 13.2 0.0 3.1 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAP56984.1 - 0.0036 15.6 0.2 0.04 12.2 0.2 2.3 1 1 2 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.3 OAP56984.1 - 0.0058 14.8 0.1 1.4 6.9 0.0 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.10 OAP56984.1 - 0.017 13.6 0.0 0.12 10.8 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain LXG PF04740.7 OAP56984.1 - 0.096 12.4 1.9 0.14 11.9 1.3 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily COMP PF11598.3 OAP56984.1 - 0.14 12.2 0.9 0.36 10.9 0.6 1.7 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Proteasome_A_N PF10584.4 OAP56984.1 - 1.8 7.9 9.1 3.8 6.9 0.0 5.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature zf-C2H2 PF00096.21 OAP56985.1 - 9.2e-12 44.5 15.8 0.00059 20.0 1.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP56985.1 - 1e-08 34.8 12.2 0.018 15.3 1.4 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP56985.1 - 2.1e-07 30.8 24.4 2.5e-07 30.6 0.8 4.8 4 1 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 OAP56985.1 - 0.004 17.3 0.6 0.14 12.4 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Mito_carr PF00153.22 OAP56986.1 - 1e-65 217.4 0.2 8.3e-22 76.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FA_hydroxylase PF04116.8 OAP56987.1 - 1.3e-14 54.6 22.9 4.2e-14 52.9 13.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2015 PF09435.5 OAP56988.1 - 8e-47 158.2 0.0 8.9e-47 158.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 OAP56989.1 - 3.8e-40 136.9 1.0 4.6e-40 136.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.13 OAP56990.1 - 2.8e-42 144.4 0.0 4e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 OAP56990.1 - 8.7e-41 139.0 0.1 7.9e-40 135.9 0.1 2.0 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 OAP56990.1 - 0.0012 17.6 0.0 0.0053 15.4 0.0 2.0 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 OAP56990.1 - 0.033 13.5 0.5 2.5 7.3 0.2 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 OAP56991.1 - 2.3e-33 114.8 0.0 3.1e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF1180 PF06679.7 OAP56991.1 - 2 8.2 6.7 3.2 7.6 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Sec16_C PF12931.2 OAP56992.1 - 2.4e-93 312.9 0.0 3.4e-93 312.4 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 OAP56992.1 - 5.7e-28 97.2 0.0 1.1e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 OAP56993.1 - 9e-20 70.6 0.1 2.6e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAP56993.1 - 2.8e-16 60.5 0.2 2.4e-15 57.5 0.2 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAP56993.1 - 1.8e-09 38.0 0.0 4.2e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP56993.1 - 8.6e-05 22.4 0.0 0.00029 20.7 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAP56993.1 - 0.0036 16.9 0.0 0.0086 15.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1795 PF08786.6 OAP56993.1 - 0.05 13.4 0.2 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) Mso1_Sec1_bdg PF14475.1 OAP56994.1 - 1.9e-11 43.1 0.1 3.4e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 YIF1 PF03878.10 OAP56996.1 - 5.4e-75 251.6 6.4 6.9e-75 251.2 4.4 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 OAP56996.1 - 0.00033 20.2 8.3 0.00033 20.2 5.7 1.8 2 0 0 2 2 2 1 Yip1 domain Chromate_transp PF02417.10 OAP56996.1 - 0.43 10.1 8.0 0.3 10.6 3.9 1.9 2 0 0 2 2 2 0 Chromate transporter PLAC8 PF04749.12 OAP56997.1 - 7.2e-24 84.3 16.5 9.4e-24 84.0 11.4 1.1 1 0 0 1 1 1 1 PLAC8 family Lactamase_B PF00753.22 OAP56998.1 - 1.8e-07 31.0 2.6 5.4e-07 29.4 1.8 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP56998.1 - 0.0084 15.6 0.1 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lipocalin_5 PF13924.1 OAP56999.1 - 3.7e-15 55.8 0.0 4.2e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Aldedh PF00171.17 OAP57000.1 - 7e-149 496.0 0.1 1.6e-148 494.9 0.1 1.5 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP57000.1 - 0.0082 14.8 0.1 0.028 13.1 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) FAD_binding_2 PF00890.19 OAP57001.1 - 1e-35 123.4 0.2 4.5e-35 121.3 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP57001.1 - 5.9e-08 32.0 0.9 1.7e-07 30.4 0.6 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 OAP57001.1 - 1.2e-07 31.2 0.1 4.6e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP57001.1 - 5.2e-06 26.4 0.0 0.0011 18.8 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP57001.1 - 0.00011 20.7 5.9 0.023 13.1 0.1 3.2 3 0 0 3 3 3 3 HI0933-like protein GMC_oxred_N PF00732.14 OAP57001.1 - 0.0025 17.0 0.0 0.0075 15.4 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAP57001.1 - 0.0053 16.7 0.4 0.02 14.9 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 OAP57001.1 - 0.007 15.2 0.5 0.007 15.2 0.3 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 OAP57001.1 - 0.02 14.4 0.1 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.20 OAP57001.1 - 0.023 13.9 0.1 0.052 12.7 0.0 1.6 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Pyr_redox_3 PF13738.1 OAP57001.1 - 0.027 14.5 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP57001.1 - 0.029 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 OAP57001.1 - 0.065 13.6 0.2 39 4.7 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.1 OAP57002.1 - 7.9e-30 104.3 0.0 1e-29 104.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57002.1 - 1.6e-27 96.5 0.5 2e-27 96.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57002.1 - 4e-12 46.1 0.1 5.5e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP57002.1 - 0.0011 18.7 1.1 0.0021 17.8 0.8 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP57002.1 - 0.0016 17.9 0.2 0.0021 17.5 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAP57002.1 - 0.079 12.6 0.5 0.11 12.1 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxysterol_BP PF01237.13 OAP57003.1 - 1.7e-72 243.9 0.0 2.1e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein MOSC_N PF03476.11 OAP57004.1 - 1.1e-17 63.8 0.0 2.1e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 OAP57004.1 - 2.8e-10 39.7 0.0 6.1e-10 38.6 0.0 1.5 2 0 0 2 2 2 1 MOSC domain Cuticle_1 PF08140.6 OAP57004.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Zn_clus PF00172.13 OAP57005.1 - 2.6e-10 40.0 9.4 4.5e-10 39.2 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP57005.1 - 5.2e-07 28.6 0.5 0.14 10.7 0.0 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Lactonase PF10282.4 OAP57006.1 - 6.9e-07 28.6 1.9 2.1e-05 23.7 0.6 3.2 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 OAP57006.1 - 0.00056 18.3 2.6 0.094 10.9 0.1 3.1 1 1 2 4 4 4 3 Cytochrome D1 heme domain HET PF06985.6 OAP57007.1 - 8.7e-11 42.1 0.1 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Catalase PF00199.14 OAP57008.1 - 1.9e-185 616.0 2.0 2.6e-185 615.5 1.4 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAP57008.1 - 2.4e-13 49.7 0.9 5.1e-13 48.6 0.1 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive Adap_comp_sub PF00928.16 OAP57010.1 - 2.1e-84 282.7 0.0 2.7e-84 282.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAP57010.1 - 1.3e-05 24.9 0.2 2.3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Myb_DNA-bind_6 PF13921.1 OAP57011.1 - 0.011 15.8 0.1 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1996 PF09362.5 OAP57012.1 - 2.7e-69 233.4 0.7 4.6e-69 232.6 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 OAP57012.1 - 8.7e-62 205.0 68.1 4.6e-17 61.7 9.7 4.6 4 0 0 4 4 4 4 WSC domain DUF2423 PF10338.4 OAP57014.1 - 2.3e-15 56.2 4.9 2.3e-15 56.2 3.4 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) THEG PF14912.1 OAP57014.1 - 2.1 8.9 5.3 6 7.4 3.7 2.1 1 1 0 1 1 1 0 Testicular haploid expressed repeat PINIT PF14324.1 OAP57015.1 - 2.2e-33 115.3 0.0 3.4e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 OAP57015.1 - 3.9e-19 67.8 1.8 6.6e-19 67.1 1.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 OAP57015.1 - 3e-07 29.7 0.1 5.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.10 OAP57015.1 - 0.049 13.1 0.2 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-Nse PF11789.3 OAP57015.1 - 0.098 12.1 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TCTP PF00838.12 OAP57015.1 - 0.42 10.5 1.0 0.86 9.5 0.5 1.6 2 0 0 2 2 2 0 Translationally controlled tumour protein Methyltransf_18 PF12847.2 OAP57016.1 - 5e-17 62.5 0.0 9.3e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP57016.1 - 9.7e-15 54.4 0.0 3.3e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP57016.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP57016.1 - 0.00017 22.0 0.1 0.0017 18.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP57016.1 - 0.00025 21.3 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP57016.1 - 0.00034 20.3 0.0 0.0018 18.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP57016.1 - 0.0011 19.4 0.0 0.0045 17.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP57016.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 OAP57016.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.5 OAP57016.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 SRP-alpha_N PF04086.8 OAP57017.1 - 8.4e-67 225.4 0.0 1.1e-66 225.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 OAP57017.1 - 1.6e-48 164.7 0.1 2.8e-48 163.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ArgK PF03308.11 OAP57017.1 - 6e-07 28.5 0.0 1.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 OAP57017.1 - 2.4e-06 27.0 0.4 2.4e-06 27.0 0.3 2.0 2 1 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 OAP57017.1 - 8.1e-06 25.8 0.0 4.1e-05 23.6 0.0 2.3 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain Longin PF13774.1 OAP57017.1 - 0.0039 16.7 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain MMR_HSR1 PF01926.18 OAP57017.1 - 0.0074 16.2 0.1 0.028 14.3 0.1 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 OAP57017.1 - 0.016 15.4 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 OAP57017.1 - 0.018 14.5 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.1 OAP57017.1 - 0.025 14.1 1.3 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 OAP57017.1 - 0.043 13.5 0.0 0.043 13.5 0.0 2.1 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 OAP57017.1 - 0.062 12.6 0.0 0.062 12.6 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 OAP57017.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 OAP57017.1 - 0.38 10.8 0.0 0.38 10.8 0.0 2.2 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 OAP57017.1 - 5.1 6.8 6.6 0.75 9.5 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function DUF87 AIM24 PF01987.12 OAP57018.1 - 7e-50 169.4 0.4 8.2e-50 169.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Pex14_N PF04695.8 OAP57018.1 - 7.3 6.6 6.4 12 5.9 4.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S41 PF03572.13 OAP57019.1 - 4.2e-08 32.7 0.0 1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 CAF-1_p150 PF11600.3 OAP57020.1 - 0.0064 15.8 7.3 0.01 15.2 5.1 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Zip PF02535.17 OAP57020.1 - 1.1 8.2 7.4 0.27 10.1 2.9 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DUF605 PF04652.11 OAP57020.1 - 2.7 7.3 11.4 3.9 6.7 7.9 1.3 1 0 0 1 1 1 0 Vta1 like TPR_12 PF13424.1 OAP57021.1 - 1.2e-12 47.6 0.1 1.6e-08 34.3 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP57021.1 - 8.1e-08 31.6 1.1 0.23 11.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAP57021.1 - 2.3e-06 27.3 0.1 0.034 14.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAP57021.1 - 3.9e-06 27.3 4.1 1.3e-05 25.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP57021.1 - 7.6e-06 26.1 0.2 0.0006 20.1 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP57021.1 - 0.0001 22.5 7.7 0.017 15.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAP57021.1 - 0.00041 19.9 0.0 0.093 12.3 0.0 2.6 2 1 1 3 3 3 2 TPR repeat PPR_3 PF13812.1 OAP57021.1 - 0.0038 17.4 2.2 4.5 7.7 0.0 3.9 4 0 0 4 4 4 1 Pentatricopeptide repeat domain TPR_4 PF07721.9 OAP57021.1 - 0.0047 17.2 5.0 1.6 9.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_1 PF12854.2 OAP57021.1 - 0.0082 15.6 0.6 0.21 11.0 0.2 2.4 2 0 0 2 2 2 1 PPR repeat TPR_7 PF13176.1 OAP57021.1 - 0.072 12.9 1.9 1.1 9.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 OAP57021.1 - 0.074 13.0 0.2 17 5.6 0.1 3.0 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.1 OAP57021.1 - 0.18 12.3 4.4 23 5.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1479 PF07350.7 OAP57023.1 - 3e-160 533.2 0.0 3.6e-160 533.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) adh_short PF00106.20 OAP57024.1 - 7.1e-17 61.8 0.0 1.6e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57024.1 - 4.3e-11 43.0 0.0 0.00011 22.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP57024.1 - 1e-06 28.5 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Ank PF00023.25 OAP57024.1 - 0.0084 15.8 0.0 0.16 11.8 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeat Epimerase PF01370.16 OAP57024.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.8 1 1 3 4 4 4 0 NAD dependent epimerase/dehydratase family Ank_2 PF12796.2 OAP57024.1 - 0.11 12.8 0.0 0.88 9.9 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) 2-Hacid_dh_C PF02826.14 OAP57024.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aa_trans PF01490.13 OAP57025.1 - 1.2e-93 313.7 14.7 1.2e-93 313.7 10.2 1.6 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 OAP57025.1 - 0.00014 20.8 18.3 0.00014 20.8 12.7 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SK_channel PF03530.9 OAP57025.1 - 8.8 6.1 9.9 0.6 9.9 0.2 3.0 3 0 0 3 3 3 0 Calcium-activated SK potassium channel Bax1-I PF01027.15 OAP57026.1 - 1.2e-48 165.4 32.1 1.4e-48 165.2 22.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.1 OAP57026.1 - 0.051 13.0 0.2 0.16 11.4 0.2 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL DUF2374 PF09574.5 OAP57026.1 - 3.2 7.4 7.9 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) Saccharop_dh PF03435.13 OAP57027.1 - 2.3e-128 428.4 0.0 2.7e-128 428.2 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 OAP57027.1 - 3.3e-07 30.4 0.1 6.8e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 OAP57027.1 - 8.7e-06 25.8 0.1 4.4e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding IlvN PF07991.7 OAP57027.1 - 0.04 13.2 0.1 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 OAP57027.1 - 0.05 13.8 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 OAP57027.1 - 0.1 13.1 0.0 0.67 10.4 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_23 PF13489.1 OAP57028.1 - 2.2e-08 34.0 0.0 3.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP57028.1 - 0.0025 18.2 0.0 0.0041 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP57028.1 - 0.027 14.9 0.0 0.064 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Beta-TrCP_D PF12125.3 OAP57028.1 - 0.078 12.5 0.1 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 D domain of beta-TrCP Ribosomal_L28e PF01778.12 OAP57029.1 - 8.1e-30 103.6 0.2 1.7e-29 102.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 OAP57029.1 - 2.1e-22 79.1 17.3 2.1e-22 79.1 12.0 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 OAP57029.1 - 0.0025 16.9 25.5 0.0038 16.3 17.5 1.4 1 1 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.7 OAP57029.1 - 0.016 13.6 25.1 0.02 13.2 17.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 OAP57029.1 - 0.86 7.4 28.0 1.1 7.0 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family GDI PF00996.13 OAP57030.1 - 3.1e-42 144.3 0.0 6.1e-41 140.1 0.0 2.0 1 1 0 1 1 1 1 GDP dissociation inhibitor TauD PF02668.11 OAP57031.1 - 7.4e-50 170.0 0.8 7.6e-50 169.9 0.1 1.3 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family zf-FPG_IleRS PF06827.9 OAP57032.1 - 0.0013 18.2 1.8 0.0013 18.2 1.3 3.2 5 0 0 5 5 5 1 Zinc finger found in FPG and IleRS F-box PF00646.28 OAP57032.1 - 0.0017 17.9 0.0 0.004 16.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain MRF_C1 PF13887.1 OAP57032.1 - 0.12 11.3 1.1 0.62 9.1 0.0 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 F-box PF00646.28 OAP57033.1 - 0.00097 18.7 0.2 0.0023 17.5 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 OAP57033.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like PRANC PF09372.5 OAP57033.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.5 2 0 0 2 2 2 0 PRANC domain Herpes_UL56 PF04534.7 OAP57033.1 - 0.099 12.3 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus UL56 protein Zn_clus PF00172.13 OAP57034.1 - 5.4e-09 35.8 6.1 8.1e-09 35.2 4.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.3 OAP57036.1 - 6.4e-07 29.3 0.1 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP57036.1 - 0.0029 17.5 1.6 0.0029 17.5 1.1 2.1 2 0 0 2 2 2 1 bZIP transcription factor TRP PF06011.7 OAP57037.1 - 4.4e-90 302.3 15.9 7.2e-90 301.6 11.1 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 OAP57037.1 - 3.2e-30 105.0 0.4 4.9e-30 104.4 0.3 1.3 1 0 0 1 1 1 1 ML-like domain DHDPS PF00701.17 OAP57038.1 - 1.6e-40 138.5 0.0 1.8e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family His_Phos_2 PF00328.17 OAP57039.1 - 3.8e-36 125.1 0.0 4.4e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Acetyltransf_1 PF00583.19 OAP57040.1 - 1.9e-10 40.6 0.0 3.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP57040.1 - 9.8e-10 38.4 0.3 1.8e-09 37.6 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP57040.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MSP1_C PF07462.6 OAP57040.1 - 2.6 6.3 9.0 3.6 5.8 6.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cyclin PF08613.6 OAP57041.1 - 1.3e-12 48.3 0.0 3.4e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAP57041.1 - 0.005 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyrid_oxidase_2 PF13883.1 OAP57042.1 - 8.6e-35 119.9 0.0 1.3e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HSP9_HSP12 PF04119.7 OAP57043.1 - 4.5e-24 84.2 7.9 4.5e-24 84.2 5.5 3.0 2 1 1 3 3 3 1 Heat shock protein 9/12 Tape_meas_lam_C PF09718.5 OAP57043.1 - 0.00087 19.1 14.2 0.0083 16.0 2.9 2.9 2 1 1 3 3 3 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) LYTB PF02401.13 OAP57043.1 - 0.021 13.7 2.4 0.023 13.6 1.6 1.1 1 0 0 1 1 1 0 LytB protein YtxH PF12732.2 OAP57043.1 - 0.053 13.8 1.8 0.053 13.8 1.2 3.1 1 1 2 3 3 3 0 YtxH-like protein Prominin PF05478.6 OAP57043.1 - 0.19 9.1 4.4 0.21 9.1 3.1 1.2 1 0 0 1 1 1 0 Prominin DUF883 PF05957.8 OAP57043.1 - 0.25 11.7 9.2 0.66 10.4 1.1 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 OAP57043.1 - 0.27 10.7 4.5 1.5 8.3 3.1 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Syntaxin-6_N PF09177.6 OAP57043.1 - 2.8 8.4 5.2 6.6 7.2 1.5 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DNA_pol_viral_N PF00242.12 OAP57043.1 - 5 6.0 10.7 5.5 5.9 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ATP-synt_B PF00430.13 OAP57043.1 - 5.6 6.7 9.5 24 4.7 6.6 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) CRAL_TRIO PF00650.15 OAP57044.1 - 7.9e-15 54.6 0.0 1.1e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAP57044.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain GATA PF00320.22 OAP57045.1 - 9.6e-17 60.0 2.1 2e-16 59.0 1.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 OAP57045.1 - 5.1e-13 48.3 6.6 8.9e-13 47.5 4.6 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.6 OAP57045.1 - 0.00011 22.6 1.9 0.00011 22.6 1.3 5.2 5 1 1 6 6 6 1 Nitrogen regulatory protein AreA N terminus Robl_LC7 PF03259.12 OAP57046.1 - 0.0038 16.7 0.0 0.94 9.0 0.0 2.3 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 OAP57047.1 - 1.4e-21 76.3 0.9 4.6e-21 74.7 0.0 2.3 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Amino_oxidase PF01593.19 OAP57048.1 - 9.1e-42 143.6 0.1 1.6e-41 142.8 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP57048.1 - 2.5e-12 46.6 0.1 4.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP57048.1 - 7.3e-08 32.7 0.0 1.8e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP57048.1 - 3e-06 26.3 0.0 4.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAP57048.1 - 0.00015 20.9 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 OAP57048.1 - 0.00046 18.7 0.0 0.0015 17.1 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 OAP57048.1 - 0.00063 18.7 0.1 0.0058 15.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 OAP57048.1 - 0.00097 18.3 0.1 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP57048.1 - 0.0033 16.4 0.0 0.091 11.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAP57048.1 - 0.022 14.6 0.0 0.057 13.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP57048.1 - 0.064 13.6 0.1 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP57048.1 - 0.088 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Abhydrolase_6 PF12697.2 OAP57050.1 - 1.2e-11 44.9 0.0 1.6e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAP57050.1 - 1.9e-10 39.7 0.0 1.7e-05 23.4 0.0 3.0 3 0 0 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 OAP57050.1 - 2.5e-10 40.3 0.0 4.5e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAP57050.1 - 2.3e-05 23.9 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 OAP57050.1 - 3.5e-05 23.1 0.0 0.00012 21.3 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 OAP57050.1 - 0.00032 20.4 0.0 0.0025 17.5 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 OAP57050.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase GST_N_3 PF13417.1 OAP57051.1 - 3.5e-06 27.1 0.1 1.4e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP57051.1 - 0.00042 20.2 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP57051.1 - 0.00072 19.3 0.0 0.0089 15.9 0.1 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP57051.1 - 0.084 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_C48 PF02902.14 OAP57052.1 - 4.2e-23 82.1 0.0 7.3e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HD_3 PF13023.1 OAP57052.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 HD domain PAP2 PF01569.16 OAP57053.1 - 5.2e-18 64.9 2.2 5.2e-18 64.9 1.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily Ras PF00071.17 OAP57054.1 - 2.2e-49 166.9 0.0 2.9e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP57054.1 - 4.8e-12 46.4 0.0 7.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP57054.1 - 8.3e-06 25.1 0.0 1.8e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAP57054.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DASH_Dad1 PF08649.5 OAP57055.1 - 2.6e-20 71.8 0.2 3.2e-20 71.5 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Med8 PF10232.4 OAP57055.1 - 0.089 12.2 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 LSM PF01423.17 OAP57056.1 - 3.3e-21 74.5 0.1 4e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.8 OAP57057.1 - 5.5e-48 162.4 0.1 6e-48 162.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Herpes_UL55 PF04537.7 OAP57057.1 - 0.0048 16.3 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL55 protein PHD PF00628.24 OAP57057.1 - 0.036 13.7 1.1 0.067 12.8 0.8 1.5 1 0 0 1 1 1 0 PHD-finger DUF3716 PF12511.3 OAP57057.1 - 0.96 9.1 5.2 2.1 7.9 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) HET PF06985.6 OAP57058.1 - 5e-28 98.0 0.1 9.9e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HA2 PF04408.18 OAP57059.1 - 4.7e-16 58.6 0.0 1.3e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAP57059.1 - 7.8e-14 51.3 0.2 2e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP57059.1 - 3.8e-11 42.7 0.5 3e-10 39.8 0.1 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 OAP57059.1 - 0.00051 19.8 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 OAP57059.1 - 0.0017 18.5 0.1 0.0052 16.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain adh_short PF00106.20 OAP57060.1 - 8.8e-25 87.5 0.3 2.1e-24 86.3 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57060.1 - 5e-24 85.3 0.0 6.3e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP57060.1 - 1.8e-06 27.7 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP57060.1 - 0.017 14.8 1.4 0.063 13.0 0.7 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RF-1 PF00472.15 OAP57061.1 - 8e-24 83.6 3.9 1.2e-23 83.0 2.7 1.2 1 0 0 1 1 1 1 RF-1 domain MMR1 PF08505.5 OAP57061.1 - 0.038 14.0 3.0 0.037 14.0 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RabGAP-TBC PF00566.13 OAP57063.1 - 2.3e-32 112.1 10.8 1.1e-29 103.4 3.5 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 OAP57063.1 - 6.9e-12 45.1 0.0 1.8e-06 27.3 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF3548) Rap_GAP PF02145.10 OAP57064.1 - 1.2e-42 145.4 0.0 1.9e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 OAP57064.1 - 2.3e-16 59.8 2.7 2.6e-15 56.3 0.2 2.9 3 0 0 3 3 3 1 Tuberin DUF3384 PF11864.3 OAP57064.1 - 4.3e-11 41.9 0.0 7.2e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) CAS_CSE1 PF03378.10 OAP57065.1 - 3.2e-162 539.7 0.0 1.2e-161 537.8 0.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 OAP57065.1 - 6.8e-148 492.1 0.2 9.7e-148 491.6 0.1 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 OAP57065.1 - 4.1e-13 49.0 0.0 2e-12 46.8 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 OAP57065.1 - 0.017 15.0 1.8 0.26 11.1 0.0 3.5 4 1 1 5 5 5 0 Exportin 1-like protein Fcf2 PF08698.6 OAP57067.1 - 2.7e-29 101.0 0.2 6.4e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Mpv17_PMP22 PF04117.7 OAP57069.1 - 1.7e-23 82.0 3.9 8.6e-22 76.5 0.6 2.4 2 0 0 2 2 2 2 Mpv17 / PMP22 family TcpE PF12648.2 OAP57069.1 - 0.083 13.0 2.4 9.1 6.4 0.0 2.8 2 1 1 3 3 3 0 TcpE family CBFD_NFYB_HMF PF00808.18 OAP57070.1 - 5.1e-19 68.0 0.6 7e-19 67.6 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAP57070.1 - 1.8e-12 47.1 0.1 2.6e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 OAP57070.1 - 0.024 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 OAP57071.1 - 2.2e-97 326.1 0.5 2.2e-97 326.1 0.4 2.5 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like COG2 PF06148.6 OAP57071.1 - 0.00016 21.5 5.2 0.0006 19.7 2.6 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 AAA_5 PF07728.9 OAP57071.1 - 0.0064 16.2 0.9 0.016 14.9 0.6 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF3680 PF12441.3 OAP57071.1 - 0.039 13.8 0.0 0.15 11.9 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) Sec5 PF15469.1 OAP57071.1 - 0.12 12.1 5.7 0.18 11.5 2.2 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec5 COG5 PF10392.4 OAP57071.1 - 0.99 9.3 13.4 0.018 14.9 3.0 2.8 3 1 0 4 4 4 0 Golgi transport complex subunit 5 RRM_2 PF04059.7 OAP57072.1 - 6e-39 131.9 0.2 9.8e-39 131.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 OAP57072.1 - 0.017 14.7 0.1 3.6 7.2 0.0 2.8 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 OAP57073.1 - 1.1e-21 77.4 0.5 4.3e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP57073.1 - 1.2e-11 44.6 0.1 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP57073.1 - 5.2e-08 32.9 0.0 3.6e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 OAP57073.1 - 0.02 13.7 0.1 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 OAP57073.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP57073.1 - 0.066 13.2 0.1 0.26 11.2 0.1 2.1 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 OAP57073.1 - 0.12 11.3 0.0 0.3 9.9 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein Asp PF00026.18 OAP57074.1 - 9.5e-60 202.4 0.5 1.1e-59 202.2 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAP57074.1 - 1.3e-08 34.9 1.3 3.5e-07 30.3 0.1 2.7 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAP57074.1 - 0.00013 21.5 0.0 0.023 14.2 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 OAP57074.1 - 0.0014 19.0 0.5 1.7 9.2 0.0 3.3 2 1 0 2 2 2 2 Aspartyl protease RVP PF00077.15 OAP57074.1 - 0.017 15.0 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease peroxidase PF00141.18 OAP57075.1 - 7.4e-22 77.9 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Pkinase PF00069.20 OAP57077.1 - 1.5e-64 217.6 0.0 1.8e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP57077.1 - 3e-30 105.1 0.0 4.1e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP57077.1 - 0.0011 18.0 0.0 0.0027 16.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 OAP57077.1 - 0.24 10.7 0.0 0.44 9.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GFA PF04828.9 OAP57078.1 - 2.8e-17 62.4 0.0 3.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 OAP57078.1 - 0.061 13.2 1.4 0.061 13.2 1.0 2.0 2 0 0 2 2 2 0 Cysteine-rich CWC SNase PF00565.12 OAP57079.1 - 2.2e-82 272.3 0.4 4.7e-25 87.9 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 OAP57079.1 - 1.1e-26 93.0 0.0 2.6e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Tudor domain BPL_LplA_LipB PF03099.14 OAP57079.1 - 0.0022 17.9 0.0 0.0064 16.5 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SMN PF06003.7 OAP57079.1 - 0.02 13.9 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Isochorismatase PF00857.15 OAP57080.1 - 2.2e-18 66.7 0.0 2.2e-07 30.9 0.0 3.2 3 0 0 3 3 3 3 Isochorismatase family HDA2-3 PF11496.3 OAP57081.1 - 0.053 12.3 4.6 0.074 11.8 3.2 1.1 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Reo_sigmaC PF04582.7 OAP57081.1 - 1.7 7.7 10.2 1.4 8.0 4.8 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF1409 PF07197.7 OAP57081.1 - 8.8 6.4 13.9 0.22 11.6 0.5 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF1409) Fungal_trans PF04082.13 OAP57082.1 - 1.7e-29 102.4 0.0 3.2e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57082.1 - 1.3e-09 37.7 12.2 2.3e-09 37.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Endomucin PF07010.7 OAP57084.1 - 0.039 13.2 0.4 0.04 13.2 0.3 1.1 1 0 0 1 1 1 0 Endomucin DUF4202 PF13875.1 OAP57085.1 - 4.6e-75 251.3 0.1 5.1e-75 251.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Amidohydro_2 PF04909.9 OAP57086.1 - 4e-32 111.8 0.2 4.6e-32 111.6 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 OAP57086.1 - 0.0059 15.8 0.0 0.0099 15.1 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase rRNA_methylase PF06962.7 OAP57086.1 - 0.052 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative rRNA methylase SNF5 PF04855.7 OAP57088.1 - 8.6e-78 261.1 0.0 1.5e-77 260.3 0.0 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 OAP57088.1 - 6.6e-05 22.1 1.3 0.00016 20.9 0.9 1.7 1 0 0 1 1 1 1 GATA zinc finger WD40 PF00400.27 OAP57089.1 - 1e-47 158.3 21.0 3.3e-11 42.6 0.3 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 OAP57089.1 - 4.2e-06 26.5 8.3 0.014 15.1 0.4 3.9 3 1 2 5 5 5 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 OAP57089.1 - 0.025 14.4 0.1 28 4.6 0.0 3.7 5 0 0 5 5 5 0 YmzC-like protein ETC_C1_NDUFA4 PF04800.7 OAP57089.1 - 0.1 12.5 2.5 3 7.7 0.1 3.0 3 0 0 3 3 3 0 ETC complex I subunit conserved region tRNA-synt_1c PF00749.16 OAP57090.1 - 4.1e-90 301.6 0.0 9.6e-90 300.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ PF00226.26 OAP57091.1 - 4.3e-22 77.6 3.0 8.8e-22 76.6 2.1 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAP57091.1 - 3e-21 75.1 5.5 1.4e-18 66.5 0.0 3.6 4 0 0 4 4 4 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 OAP57091.1 - 1.8e-13 50.3 19.8 3.1e-13 49.5 13.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 OAP57091.1 - 0.0012 18.4 7.9 0.22 11.2 0.6 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DUF1356 PF07092.7 OAP57091.1 - 0.39 9.8 4.6 0.47 9.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zf-CHY PF05495.7 OAP57091.1 - 0.56 10.4 7.6 0.48 10.6 0.6 2.3 2 0 0 2 2 2 0 CHY zinc finger GCC2_GCC3 PF07699.8 OAP57091.1 - 3.1 7.4 10.6 6.9 6.3 1.2 2.6 2 0 0 2 2 2 0 GCC2 and GCC3 Unstab_antitox PF09720.5 OAP57091.1 - 4.5 7.0 5.4 0.9 9.2 0.2 2.3 2 1 1 3 3 3 0 Putative addiction module component DAO PF01266.19 OAP57092.1 - 2.5e-55 187.8 0.0 3e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP57092.1 - 5.2e-07 29.9 0.8 4.7e-05 23.5 0.6 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP57092.1 - 4.7e-06 26.5 0.2 1.9e-05 24.5 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP57092.1 - 8.1e-06 25.0 0.0 1.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 OAP57092.1 - 4.3e-05 22.6 0.0 6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAP57092.1 - 0.00048 19.9 0.0 0.0036 17.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP57092.1 - 0.00077 19.4 0.1 0.042 13.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP57092.1 - 0.002 17.1 0.1 0.0072 15.2 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 OAP57092.1 - 0.0095 14.8 0.5 0.041 12.7 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 OAP57092.1 - 0.042 13.4 0.4 0.07 12.7 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 OAP57092.1 - 0.1 11.0 0.5 4.4 5.6 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Rox3 PF08633.5 OAP57093.1 - 2.9e-37 128.8 0.5 5.8e-37 127.8 0.4 1.4 1 0 0 1 1 1 1 Rox3 mediator complex subunit HAD_2 PF13419.1 OAP57094.1 - 1.1e-27 97.4 0.1 1.6e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Amidase PF01425.16 OAP57096.1 - 5.8e-88 295.6 0.0 6.9e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 Amidase NmrA PF05368.8 OAP57097.1 - 2.1e-09 36.9 0.0 1.6e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP57097.1 - 0.05 13.6 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding KRAB PF01352.22 OAP57098.1 - 0.0046 16.3 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 KRAB box ADH_zinc_N PF00107.21 OAP57099.1 - 3.7e-20 71.7 0.0 5.6e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP57099.1 - 2.1e-06 28.6 0.0 3.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 OAP57099.1 - 0.16 11.9 0.1 0.46 10.4 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Aldedh PF00171.17 OAP57100.1 - 1.9e-132 441.9 0.1 2.1e-132 441.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MCM PF00493.18 OAP57101.1 - 2.7e-132 440.6 0.2 3.8e-132 440.0 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAP57101.1 - 9.9e-18 64.7 0.0 2.8e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAP57101.1 - 3.7e-06 26.2 0.0 4.6e-05 22.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAP57101.1 - 0.0027 17.4 0.0 0.0067 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 OAP57101.1 - 0.0043 16.5 0.0 0.0088 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 OAP57101.1 - 0.028 14.0 0.0 0.075 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4182 PF13790.1 OAP57101.1 - 0.13 12.0 2.4 0.56 10.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) zf-C3H1 PF10650.4 OAP57102.1 - 3.3e-05 23.2 0.7 5.3e-05 22.5 0.5 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain IncA PF04156.9 OAP57102.1 - 0.0012 18.4 15.1 0.0012 18.4 10.5 3.3 3 0 0 3 3 3 1 IncA protein Myosin_head PF00063.16 OAP57103.1 - 2e-245 816.0 0.0 2e-245 816.0 0.0 2.1 2 1 0 2 2 1 1 Myosin head (motor domain) Myosin_N PF02736.14 OAP57103.1 - 1.3e-07 31.1 0.3 3e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.1 OAP57103.1 - 0.00051 19.3 7.5 0.00051 19.3 5.2 5.7 1 1 4 5 5 5 4 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 OAP57103.1 - 0.0021 18.1 13.7 0.0021 18.1 9.5 5.1 1 1 3 4 4 4 2 Fibrinogen alpha/beta chain family Lge1 PF11488.3 OAP57103.1 - 0.018 15.2 0.5 0.018 15.2 0.4 7.7 4 1 3 7 7 4 0 Transcriptional regulatory protein LGE1 DUF4107 PF13389.1 OAP57103.1 - 0.044 13.4 0.2 0.16 11.6 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) AAA_19 PF13245.1 OAP57103.1 - 0.047 13.4 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 OAP57103.1 - 0.055 12.6 20.2 0.58 9.2 6.9 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_22 PF13401.1 OAP57103.1 - 0.15 12.1 0.0 0.15 12.1 0.0 3.6 3 1 0 3 3 2 0 AAA domain Myosin_tail_1 PF01576.14 OAP57103.1 - 2.8 5.5 102.6 9.3 3.8 71.1 1.7 1 1 0 1 1 1 0 Myosin tail AAA_13 PF13166.1 OAP57103.1 - 3.7 5.8 63.4 1.6 7.1 6.1 3.4 1 1 2 3 3 3 0 AAA domain NPV_P10 PF05531.7 OAP57103.1 - 5.5 7.3 22.3 4.7 7.5 1.8 5.4 2 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 OAP57104.1 - 1.8e-08 33.4 37.4 5.7e-08 31.8 26.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAP57104.1 - 8.8e-08 31.7 5.4 8.8e-08 31.7 3.7 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 BcrAD_BadFG PF01869.15 OAP57105.1 - 6.9e-19 68.1 0.9 1.2e-18 67.3 0.6 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.1 OAP57105.1 - 0.0013 18.4 3.1 0.0055 16.4 0.2 3.2 3 1 0 3 3 3 1 SIS domain SIS PF01380.17 OAP57105.1 - 0.0036 16.9 2.8 0.0051 16.4 0.0 2.7 3 0 0 3 3 3 1 SIS domain DDOST_48kD PF03345.9 OAP57106.1 - 1.4e-158 527.8 0.0 1.7e-158 527.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta BTB PF00651.26 OAP57108.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain GST_N_3 PF13417.1 OAP57110.1 - 9.5e-18 64.2 0.0 2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP57110.1 - 2.3e-07 30.5 0.0 4.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAP57110.1 - 1.9e-06 27.7 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP57110.1 - 6.2e-06 26.1 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAP57110.1 - 0.00012 22.5 0.2 0.0002 21.7 0.2 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldedh PF00171.17 OAP57113.1 - 1.1e-44 152.6 0.0 1.6e-33 115.7 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Flavi_glycoprot PF00869.15 OAP57113.1 - 0.011 14.7 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains DUF1487 PF07368.6 OAP57113.1 - 0.02 14.1 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) FAD_binding_3 PF01494.14 OAP57114.1 - 1.5e-13 50.5 3.5 2.7e-07 29.9 0.0 3.2 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.19 OAP57114.1 - 3.1e-10 39.5 0.3 2e-07 30.2 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP57114.1 - 8e-06 24.9 1.0 1.5e-05 24.0 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP57114.1 - 1.1e-05 25.3 1.0 3.4e-05 23.7 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP57114.1 - 2.1e-05 24.4 1.2 7e-05 22.7 0.8 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP57114.1 - 0.00018 21.8 0.5 0.0039 17.5 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP57114.1 - 0.00019 20.0 0.3 0.01 14.3 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 OAP57114.1 - 0.00049 19.1 0.0 0.62 8.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 OAP57114.1 - 0.0029 16.5 0.1 0.0067 15.3 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 OAP57114.1 - 0.021 13.8 0.4 0.036 13.1 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 OAP57114.1 - 0.045 13.5 0.7 14 5.4 0.2 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 OAP57114.1 - 0.091 11.8 0.4 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 OAP57114.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP57114.1 - 0.16 12.2 0.1 0.28 11.4 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 OAP57114.1 - 0.25 9.9 1.1 1.5 7.3 0.5 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.2 OAP57114.1 - 0.46 9.5 3.5 0.54 9.2 1.1 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase CHAT PF12770.2 OAP57115.1 - 2.4e-31 108.9 0.3 3e-31 108.6 0.2 1.1 1 0 0 1 1 1 1 CHAT domain Aminotran_3 PF00202.16 OAP57116.1 - 5.4e-91 304.9 0.0 6.5e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III AA_permease PF00324.16 OAP57117.1 - 7.8e-120 400.4 38.2 9.6e-120 400.1 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP57117.1 - 5.9e-35 120.6 40.7 7.1e-35 120.3 28.2 1.1 1 0 0 1 1 1 1 Amino acid permease Adeno_E3_14_5 PF04834.7 OAP57117.1 - 7.5 7.0 8.5 6.2 7.3 1.1 3.6 3 1 0 4 4 4 0 Early E3 14.5 kDa protein Fungal_trans PF04082.13 OAP57118.1 - 2.4e-17 62.6 0.1 3.8e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SOR_SNZ PF01680.12 OAP57119.1 - 6.2e-109 362.4 7.1 9.2e-109 361.8 4.9 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 OAP57119.1 - 1e-07 31.2 9.5 7.9e-06 25.1 1.1 2.6 1 1 2 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 OAP57119.1 - 1.9e-05 24.0 1.1 0.028 13.6 0.0 3.0 2 1 1 3 3 3 2 Histidine biosynthesis protein Dus PF01207.12 OAP57119.1 - 0.00013 20.9 0.7 0.12 11.2 0.1 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 OAP57119.1 - 0.0013 17.7 1.0 0.047 12.6 0.0 2.8 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 OAP57119.1 - 0.004 16.2 0.3 0.046 12.7 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 OAP57119.1 - 0.0081 15.3 1.3 0.0081 15.3 0.9 2.4 2 1 0 2 2 2 1 Nitronate monooxygenase TMP-TENI PF02581.12 OAP57119.1 - 0.013 14.5 1.5 0.72 8.9 0.1 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI Ribosomal_L29 PF00831.18 OAP57119.1 - 0.028 14.1 0.1 0.076 12.7 0.1 1.7 1 0 0 1 1 1 0 Ribosomal L29 protein Trp_syntA PF00290.15 OAP57119.1 - 0.071 11.6 0.0 0.13 10.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan synthase alpha chain MmgE_PrpD PF03972.9 OAP57120.1 - 2.8e-63 213.6 0.2 3.3e-63 213.4 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Methyltransf_2 PF00891.13 OAP57121.1 - 1.8e-33 115.7 0.0 2.5e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase AA_permease PF00324.16 OAP57122.1 - 7.6e-132 440.0 37.4 9.3e-132 439.7 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP57122.1 - 6.5e-40 136.9 38.3 8.8e-40 136.5 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease Asp PF00026.18 OAP57123.1 - 1.5e-35 122.9 0.2 2e-34 119.2 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAP57123.1 - 0.002 17.6 0.2 0.032 13.7 0.0 2.5 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 OAP57123.1 - 0.011 16.1 1.5 7.2 7.1 0.1 4.3 5 1 1 6 6 6 0 Aspartyl protease RVP PF00077.15 OAP57123.1 - 0.16 11.9 0.0 4.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Retroviral aspartyl protease p450 PF00067.17 OAP57125.1 - 1.7e-72 244.4 0.0 2.2e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 OAP57125.1 - 1.8e-33 115.8 0.0 3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAP57125.1 - 4.5e-20 72.1 0.0 1.2e-19 70.7 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAP57125.1 - 2e-14 54.0 0.0 8.4e-14 52.0 0.0 2.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 OAP57125.1 - 0.00048 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 OAP57125.1 - 0.0078 16.1 0.0 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 NrdI Flavodoxin like SBP_bac_5 PF00496.17 OAP57125.1 - 0.059 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle ABC2_membrane PF01061.19 OAP57126.1 - 1.9e-75 252.6 65.8 2.2e-41 141.3 14.2 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 OAP57126.1 - 7.3e-38 129.9 0.0 2.3e-19 70.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 OAP57126.1 - 1.8e-28 98.2 0.2 1.7e-23 82.2 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 OAP57126.1 - 1.8e-19 69.5 0.0 4.6e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 OAP57126.1 - 3e-07 30.0 0.2 0.0005 19.5 0.0 2.9 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.1 OAP57126.1 - 1.5e-05 25.1 2.9 0.00091 19.2 0.1 2.9 3 0 0 3 3 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 OAP57126.1 - 4.4e-05 22.6 18.4 4.4e-05 22.6 12.8 3.0 3 2 0 3 3 2 1 ABC-2 family transporter protein AAA_33 PF13671.1 OAP57126.1 - 9.4e-05 22.3 0.1 0.15 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 OAP57126.1 - 0.00017 20.7 0.4 0.00047 19.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 OAP57126.1 - 0.00018 21.5 0.7 0.42 10.5 0.0 2.7 2 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 OAP57126.1 - 0.00019 21.5 0.3 0.046 13.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 OAP57126.1 - 0.00088 18.7 1.3 0.033 13.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 OAP57126.1 - 0.0032 17.0 1.0 0.59 9.7 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 OAP57126.1 - 0.0082 15.0 0.1 0.55 9.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 OAP57126.1 - 0.0096 16.7 0.0 1.5 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAP57126.1 - 0.012 15.9 0.2 0.54 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 OAP57126.1 - 0.012 15.5 0.0 0.48 10.3 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 OAP57126.1 - 0.016 14.9 0.5 6.4 6.6 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 OAP57126.1 - 0.018 15.2 0.3 6.3 6.9 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 OAP57126.1 - 0.028 14.7 0.1 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 OAP57126.1 - 0.037 13.2 0.1 1.5 7.9 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 OAP57126.1 - 0.044 13.4 5.5 0.8 9.3 0.2 3.0 3 0 0 3 3 2 0 NACHT domain ArgK PF03308.11 OAP57126.1 - 0.058 12.1 0.1 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 OAP57126.1 - 0.12 11.6 0.2 0.55 9.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.14 OAP57126.1 - 0.32 10.4 5.6 0.13 11.6 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 OAP57126.1 - 0.33 10.9 0.3 6.1 6.8 0.1 2.7 3 0 0 3 3 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 OAP57126.1 - 0.39 10.2 1.2 13 5.2 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 OAP57126.1 - 0.44 10.0 0.6 8.2 5.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 OAP57126.1 - 0.52 9.7 1.4 2.9 7.3 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Protoglobin PF11563.3 OAP57128.1 - 1.9e-36 125.1 0.1 2.4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Ribosomal_L37 PF08561.5 OAP57129.1 - 1.2e-20 72.8 3.9 1.1e-19 69.7 2.7 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 RRM_1 PF00076.17 OAP57131.1 - 4.6e-41 138.3 0.0 2.1e-19 68.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP57131.1 - 2.4e-31 107.5 0.0 7.7e-15 54.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP57131.1 - 6.6e-19 67.5 0.0 1.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg6_Alg8 PF03155.10 OAP57132.1 - 8.8e-134 446.8 21.2 1.4e-85 287.9 6.7 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Fasciclin PF02469.17 OAP57133.1 - 0.00031 20.7 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain ADH_zinc_N PF00107.21 OAP57136.1 - 4.5e-28 97.3 0.0 6.9e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP57136.1 - 5.3e-23 80.8 0.3 9.2e-23 80.0 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP57136.1 - 5.8e-05 23.9 0.0 8.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP57136.1 - 0.0001 21.9 0.1 0.0002 20.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 OAP57136.1 - 0.00075 20.0 0.1 0.0016 19.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP57136.1 - 0.0038 17.6 0.2 0.019 15.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP57136.1 - 0.0064 16.8 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 OAP57136.1 - 0.0072 15.4 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 OAP57136.1 - 0.0074 16.2 0.2 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain DUF849 PF05853.7 OAP57136.1 - 0.014 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) CMAS PF02353.15 OAP57136.1 - 0.02 13.9 0.3 0.032 13.3 0.2 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 OAP57136.1 - 0.03 13.9 0.1 0.089 12.3 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain ApbA PF02558.11 OAP57136.1 - 0.049 13.0 0.2 0.11 11.9 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MTS PF05175.9 OAP57136.1 - 0.1 11.9 0.0 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 OAP57136.1 - 0.1 11.6 0.2 0.83 8.7 0.1 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 OAP57136.1 - 0.11 12.5 0.3 0.52 10.3 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 OAP57136.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 OAP57137.1 - 3.1e-58 197.1 0.0 5e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAP57137.1 - 2e-28 99.0 0.0 3.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAP57137.1 - 1.6e-09 37.5 0.0 2.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 OAP57137.1 - 2.8e-06 27.4 0.1 6.4e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 OAP57137.1 - 2.9e-05 22.8 0.0 0.038 12.7 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 OAP57137.1 - 0.001 19.9 0.0 0.0033 18.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 OAP57137.1 - 0.019 14.8 0.0 0.052 13.4 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.13 OAP57138.1 - 2e-23 82.6 0.2 3.5e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57138.1 - 1.5e-05 24.8 8.7 1.5e-05 24.8 6.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 OAP57139.1 - 2.2e-24 86.6 0.0 3.5e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP57139.1 - 7.6e-21 73.9 0.1 2.2e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP57139.1 - 1.9e-13 50.0 0.0 2e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP57139.1 - 2.4e-09 37.3 0.0 0.0052 16.6 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP57139.1 - 3.6e-09 36.5 0.0 1.6e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP57139.1 - 6.2e-06 26.0 0.5 0.025 14.3 0.2 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 OAP57139.1 - 0.0011 19.3 0.0 0.0065 16.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP57139.1 - 0.0057 15.6 1.6 0.65 8.8 0.1 3.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAP57139.1 - 0.0063 16.7 0.0 0.22 11.8 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.9 OAP57139.1 - 0.023 13.1 0.6 3.9 5.8 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 OAP57139.1 - 0.043 12.9 0.0 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAP57139.1 - 0.076 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 OAP57139.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 OAP57139.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 OAP57139.1 - 0.16 10.8 0.4 2.9 6.7 0.1 2.7 3 1 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.12 OAP57139.1 - 0.17 10.9 1.0 35 3.3 0.0 3.0 3 0 0 3 3 3 0 Thi4 family Aldo_ket_red PF00248.16 OAP57141.1 - 4.4e-63 212.7 0.0 6.7e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 OAP57141.1 - 0.00065 18.6 0.1 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 OAP57143.1 - 1.7e-25 90.2 0.0 2.2e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57143.1 - 3.9e-23 82.1 0.2 6.1e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57143.1 - 1.2e-07 31.5 0.1 2.3e-07 30.6 0.1 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 OAP57143.1 - 0.0044 15.9 0.0 0.044 12.6 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.16 OAP57143.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SHD1 PF03983.7 OAP57144.1 - 1.4e-33 114.3 0.1 2.4e-33 113.5 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 OAP57144.1 - 2.1e-33 113.4 12.3 2.3e-13 49.3 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 OAP57144.1 - 1.6e-27 94.8 10.4 1.2e-10 40.7 0.3 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 OAP57144.1 - 8.4e-20 70.0 0.2 5.2e-06 25.8 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 OAP57144.1 - 0.0016 18.6 7.8 0.11 12.6 0.6 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain Imm2 PF14426.1 OAP57144.1 - 0.33 10.9 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm2 DUF1720 PF08226.6 OAP57144.1 - 1.3 9.1 176.3 0.12 12.5 23.3 6.7 1 1 4 5 5 5 0 Domain of unknown function (DUF1720) PRKCSH PF07915.8 OAP57145.1 - 1.6e-18 67.2 2.2 2.3e-18 66.7 0.1 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 OAP57145.1 - 0.058 12.8 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein LRR_6 PF13516.1 OAP57146.1 - 4.3e-15 54.0 3.7 0.012 15.6 0.0 7.5 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.2 OAP57146.1 - 3.4e-07 29.7 10.5 0.81 9.3 0.0 6.5 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 OAP57146.1 - 8.4e-07 28.1 1.9 19 5.7 0.0 7.0 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 OAP57146.1 - 0.0012 18.5 10.5 7.7 6.3 0.1 5.8 3 2 2 5 5 5 1 Leucine rich repeat LRR_7 PF13504.1 OAP57146.1 - 0.046 13.9 2.6 4.3e+02 1.9 0.0 6.1 7 0 0 7 7 7 0 Leucine rich repeat HNF-1_N PF04814.8 OAP57146.1 - 0.11 12.5 9.5 1.1 9.2 5.1 2.7 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF106 PF01956.11 OAP57147.1 - 1.9e-56 190.2 0.2 2.7e-56 189.7 0.2 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 zf-C4_Topoisom PF01396.14 OAP57148.1 - 0.028 13.9 0.3 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger NDUFA12 PF05071.11 OAP57149.1 - 1.6e-08 34.9 0.7 1.6e-08 34.9 0.5 1.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.26 OAP57150.1 - 1.7e-11 44.1 0.0 3.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAF-1_p150 PF11600.3 OAP57150.1 - 0.0018 17.7 31.2 0.0018 17.7 21.6 3.4 1 1 3 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 OAP57150.1 - 2.2 6.4 33.1 0.027 12.7 15.7 2.2 2 1 0 2 2 2 0 Transmembrane protein FAD_binding_3 PF01494.14 OAP57152.1 - 7.4e-18 64.7 0.9 6.1e-17 61.7 0.6 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP57152.1 - 9.3e-06 24.7 0.1 3.1e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP57152.1 - 7.4e-05 22.6 0.2 0.00021 21.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP57152.1 - 0.003 17.3 0.2 0.058 13.1 0.2 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP57152.1 - 0.0049 16.7 0.0 0.0054 16.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP57152.1 - 0.0097 14.7 0.9 0.014 14.2 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain SE PF08491.5 OAP57152.1 - 0.01 14.6 0.0 0.08 11.7 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 OAP57152.1 - 0.014 14.0 2.2 0.063 11.8 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 OAP57152.1 - 0.017 13.6 0.1 0.025 13.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 OAP57152.1 - 0.018 15.4 0.2 0.048 14.0 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP57152.1 - 0.018 15.1 0.1 0.1 12.6 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 OAP57152.1 - 0.082 12.5 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 OAP57152.1 - 0.12 11.2 0.1 1.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 OAP57152.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 OAP57152.1 - 0.14 10.9 0.3 0.23 10.2 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_N PF08240.7 OAP57153.1 - 2.7e-22 78.5 0.3 4.1e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP57153.1 - 1.2e-15 57.2 0.0 1.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 OAP57153.1 - 1.3e-05 24.7 0.1 4.1e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 OAP57153.1 - 0.00097 20.0 0.0 0.0018 19.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 OAP57153.1 - 0.077 13.0 0.1 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MatE PF01554.13 OAP57154.1 - 2.8e-08 33.5 14.4 2e-05 24.2 1.7 3.5 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.1 OAP57154.1 - 0.01 15.6 2.3 0.01 15.6 1.6 2.8 4 0 0 4 4 4 0 Polysaccharide biosynthesis C-terminal domain Aminotran_1_2 PF00155.16 OAP57155.1 - 1e-46 159.5 0.0 1.3e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Nbl1_Borealin_N PF10444.4 OAP57156.1 - 4.3e-19 67.6 5.5 7.6e-19 66.8 3.8 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Toxin_10 PF05431.6 OAP57156.1 - 0.058 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 DUF3546 PF12066.3 OAP57157.1 - 2.3e-27 95.2 2.5 2.3e-27 95.2 1.8 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 OAP57157.1 - 1.9e-23 81.8 0.4 6.1e-23 80.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 OAP57157.1 - 9.1e-09 35.8 0.7 2.3e-08 34.4 0.5 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 TspO_MBR PF03073.10 OAP57159.1 - 7.8e-43 145.5 2.8 1.3e-42 144.8 1.9 1.3 1 0 0 1 1 1 1 TspO/MBR family Corona_NS3b PF03053.9 OAP57159.1 - 0.17 11.4 0.3 0.23 11.0 0.2 1.1 1 0 0 1 1 1 0 ORF3b coronavirus protein Zip PF02535.17 OAP57160.1 - 6.7e-47 160.0 2.8 8.4e-47 159.7 1.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Abhydrolase_6 PF12697.2 OAP57161.1 - 6.8e-23 81.7 0.4 1e-22 81.1 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP57161.1 - 2.1e-10 40.5 0.0 5.8e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP57161.1 - 0.00083 18.9 0.0 0.0052 16.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAP57161.1 - 0.07 12.9 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Scytalone_dh PF02982.9 OAP57162.1 - 3.2e-83 277.0 2.1 4.1e-83 276.7 1.5 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 OAP57162.1 - 2.1e-06 27.6 1.0 3.3e-06 27.0 0.7 1.3 1 0 0 1 1 1 1 SnoaL-like domain Vint PF14623.1 OAP57163.1 - 2.7e-48 163.5 0.0 4.1e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 OAP57163.1 - 4.8e-25 87.4 0.0 1.2e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 OAP57163.1 - 1.8e-18 67.2 0.0 6.8e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 OAP57163.1 - 7.3e-15 55.1 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 OAP57163.1 - 3.1e-08 33.4 0.3 2.4e-05 24.0 0.0 3.4 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 OAP57163.1 - 0.11 11.6 0.2 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Peptidase_C1_2 PF03051.10 OAP57163.1 - 0.27 9.7 0.0 0.4 9.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Epimerase PF01370.16 OAP57164.1 - 3.8e-15 55.9 0.0 6.4e-15 55.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP57164.1 - 3.3e-12 45.6 0.0 7.6e-12 44.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP57164.1 - 4.5e-11 43.1 0.0 1e-10 41.9 0.0 1.6 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 OAP57164.1 - 1.5e-05 25.0 1.8 2.2e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 OAP57164.1 - 4.7e-05 22.7 0.1 7.1e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 OAP57164.1 - 0.00012 21.1 0.0 0.0023 16.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 OAP57164.1 - 0.08 11.8 0.0 0.6 8.9 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain HLH PF00010.21 OAP57165.1 - 1.7e-15 56.4 0.4 3.1e-15 55.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3450 PF11932.3 OAP57165.1 - 0.13 11.4 2.7 0.19 10.9 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2207 PF09972.4 OAP57166.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PSDC PF12588.3 OAP57167.1 - 5.4e-52 175.1 0.0 8.1e-52 174.5 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 OAP57167.1 - 2.2e-36 125.0 0.0 3.6e-35 121.1 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 OAP57167.1 - 0.0002 20.9 0.4 0.033 13.8 0.1 2.3 2 0 0 2 2 2 2 Biotin-lipoyl like Peptidase_M23 PF01551.17 OAP57167.1 - 0.027 14.5 0.1 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M23 RnfC_N PF13375.1 OAP57167.1 - 0.086 12.5 0.1 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HPP PF04982.8 OAP57168.1 - 5.2e-39 132.8 5.6 1e-38 131.8 3.9 1.5 1 0 0 1 1 1 1 HPP family BCLP PF12304.3 OAP57168.1 - 0.27 10.6 1.4 0.53 9.6 1.0 1.4 1 0 0 1 1 1 0 Beta-casein like protein Peptidase_M1 PF01433.15 OAP57169.1 - 1.5e-69 235.0 0.0 2e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 OAP57169.1 - 2e-43 147.4 0.0 4.6e-42 143.0 0.0 2.3 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 OAP57169.1 - 3.5e-17 62.6 0.1 6.2e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 OAP57169.1 - 0.14 12.1 2.4 0.97 9.4 1.7 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Grp1_Fun34_YaaH PF01184.14 OAP57170.1 - 1.9e-28 99.2 18.0 2.4e-28 98.8 12.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cytochrom_B561 PF03188.11 OAP57170.1 - 0.71 9.6 11.5 1.6 8.5 2.8 2.5 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 ATP-synt_E PF05680.7 OAP57171.1 - 8.5e-22 76.9 0.1 9.2e-22 76.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.27 OAP57172.1 - 1.9e-16 59.1 12.9 4.6e-05 23.1 0.1 6.1 4 2 0 4 4 4 4 WD domain, G-beta repeat Cas_Csy4 PF09618.5 OAP57172.1 - 0.32 10.7 8.8 0.48 10.2 2.6 2.5 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Ureidogly_hydro PF04115.7 OAP57173.1 - 4.5e-48 162.6 0.0 5.4e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase zf-RING_2 PF13639.1 OAP57174.1 - 5.3e-09 35.7 3.7 1.1e-08 34.7 2.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAP57174.1 - 2.7e-07 30.6 2.8 7e-07 29.2 2.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAP57174.1 - 4e-06 26.5 2.0 1.2e-05 25.0 1.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 OAP57174.1 - 0.00089 19.2 4.2 0.0018 18.2 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP57174.1 - 0.013 15.1 0.6 0.032 13.8 0.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 OAP57174.1 - 0.045 13.8 0.1 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.24 OAP57174.1 - 0.049 13.3 2.6 0.091 12.4 1.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 OAP57174.1 - 0.083 12.6 1.9 0.17 11.6 1.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 OAP57174.1 - 0.15 12.0 2.8 0.4 10.6 1.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 OAP57174.1 - 1.2 8.7 4.5 19 4.9 3.5 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ion_trans_2 PF07885.11 OAP57178.1 - 6e-28 96.3 24.7 7.2e-15 54.4 4.6 3.1 3 0 0 3 3 3 2 Ion channel LIX1 PF14954.1 OAP57178.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Limb expression 1 HCV_NS4a PF01006.15 OAP57178.1 - 0.65 9.5 4.6 13 5.3 0.1 3.0 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a ATP-synt PF00231.14 OAP57181.1 - 4.7e-69 232.9 1.5 5.4e-69 232.7 1.0 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.10 OAP57182.1 - 5.6e-96 319.9 3.6 5.6e-96 319.9 2.5 3.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 OAP57182.1 - 9.3e-78 260.5 3.7 9.3e-78 260.5 2.6 3.1 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 OAP57182.1 - 4.9e-32 109.4 0.5 2.1e-31 107.4 0.4 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain CBFB_NFYA PF02045.10 OAP57183.1 - 4.8e-31 107.0 4.1 8.8e-31 106.2 2.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 OAP57183.1 - 0.028 13.3 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Cwf_Cwc_15 PF04889.7 OAP57183.1 - 0.086 12.5 3.4 0.11 12.1 2.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein IER PF05760.7 OAP57183.1 - 0.2 11.5 6.3 0.25 11.2 4.4 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) PAT1 PF09770.4 OAP57183.1 - 3.6 5.7 14.4 3.5 5.7 10.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3818 PF12825.2 OAP57184.1 - 3.8e-136 453.2 0.2 4.9e-136 452.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 OAP57185.1 - 8.8e-43 145.1 0.7 1.3e-42 144.7 0.5 1.1 1 0 0 1 1 1 1 PX-associated PX PF00787.19 OAP57185.1 - 4.9e-10 39.1 0.6 1.1e-09 38.1 0.1 1.7 2 0 0 2 2 2 1 PX domain ADH_zinc_N PF00107.21 OAP57186.1 - 1.2e-11 44.2 0.0 2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP57186.1 - 1.4e-05 24.8 0.1 4.8e-05 23.0 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PEP_mutase PF13714.1 OAP57186.1 - 0.021 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase S4 PF01479.20 OAP57187.1 - 1.1e-10 40.7 0.0 2.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 OAP57187.1 - 1.4e-09 38.2 0.7 2e-09 37.7 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF3399 PF11879.3 OAP57187.1 - 0.032 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) MFS_1 PF07690.11 OAP57189.1 - 6.6e-12 44.8 3.9 7e-12 44.7 2.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP57189.1 - 0.00031 19.4 1.3 0.00031 19.4 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 OAP57191.1 - 1e-85 288.0 20.2 1.2e-85 287.7 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57191.1 - 2.6e-15 56.0 35.8 9.8e-14 50.8 20.2 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP57191.1 - 2.7e-06 26.0 23.2 0.0016 16.9 1.2 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein Alpha-amylase PF00128.19 OAP57192.1 - 1.8e-97 326.5 0.2 2.9e-97 325.8 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 OAP57192.1 - 0.015 14.2 0.1 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_70 PF02324.11 OAP57192.1 - 0.062 11.0 0.0 0.089 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 NmrA PF05368.8 OAP57193.1 - 1.3e-26 93.3 0.0 1.6e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP57193.1 - 0.0001 22.3 0.2 0.00019 21.4 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 OAP57193.1 - 0.014 15.3 0.1 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 OAP57193.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 OAP57193.1 - 0.073 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 OAP57193.1 - 0.08 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 OAP57193.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Amidase PF01425.16 OAP57194.1 - 4e-72 243.4 0.0 4.6e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Amidase CytB6-F_Fe-S PF08802.5 OAP57194.1 - 0.089 12.8 0.1 0.27 11.2 0.1 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Methyltransf_2 PF00891.13 OAP57195.1 - 8.2e-29 100.4 0.1 1.4e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase FMO-like PF00743.14 OAP57196.1 - 6.3e-31 107.1 0.0 1.8e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAP57196.1 - 2.5e-20 73.4 0.0 2.4e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP57196.1 - 4.9e-15 55.2 0.1 9.8e-13 47.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP57196.1 - 1.8e-14 54.0 0.0 6e-11 42.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP57196.1 - 2.4e-07 30.6 0.0 7.6e-06 25.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP57196.1 - 4.1e-06 26.6 1.7 0.0095 15.7 0.2 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.12 OAP57196.1 - 8.3e-05 21.7 0.2 0.0014 17.8 0.1 2.4 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.22 OAP57196.1 - 0.00012 22.3 0.5 0.87 10.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP57196.1 - 0.0004 19.3 0.6 0.025 13.4 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP57196.1 - 0.00083 17.9 1.2 0.013 14.0 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 OAP57196.1 - 0.0012 17.9 0.7 0.041 12.9 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 OAP57196.1 - 0.017 14.2 0.0 0.017 14.2 0.0 1.5 2 0 0 2 2 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 OAP57196.1 - 0.063 13.3 0.1 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAP57196.1 - 0.091 13.0 0.1 21 5.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 OAP57196.1 - 0.12 12.3 1.1 3.7 7.4 0.0 2.9 4 0 0 4 4 4 0 NADH(P)-binding FAD_binding_2 PF00890.19 OAP57196.1 - 0.5 9.1 3.6 0.29 9.9 0.4 2.1 2 1 1 3 3 3 0 FAD binding domain SNF2_N PF00176.18 OAP57197.1 - 5.8e-60 202.6 0.0 8.6e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP57197.1 - 4.6e-09 36.0 0.0 1.2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 OAP57197.1 - 8.4e-05 22.2 11.3 0.00025 20.7 7.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAP57197.1 - 0.0014 18.3 7.8 0.0039 16.9 5.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAP57197.1 - 0.26 11.1 10.8 0.58 10.0 7.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 OAP57197.1 - 0.28 11.2 14.8 0.29 11.2 8.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP57197.1 - 0.45 10.2 13.1 1.4 8.6 9.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAP57197.1 - 4.8 6.9 11.5 1.1 9.0 4.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger FNIP_N PF14636.1 OAP57198.1 - 1.6e-09 38.3 0.0 1.6e-09 38.3 0.0 3.8 3 2 1 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 OAP57198.1 - 0.00026 20.6 0.1 0.00082 19.0 0.0 1.8 1 1 1 2 2 2 1 Folliculin-interacting protein middle domain RAP1 PF07218.6 OAP57198.1 - 0.079 11.0 2.5 0.15 10.1 1.7 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3608 PF12257.3 OAP57199.1 - 3e-72 242.8 0.0 4.7e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 OAP57199.1 - 1.9e-27 94.8 0.2 3.9e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GDA1_CD39 PF01150.12 OAP57200.1 - 1.7e-47 161.9 0.0 2.2e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Methyltransf_11 PF08241.7 OAP57202.1 - 1.5e-13 51.0 0.0 3.8e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP57202.1 - 1.6e-12 47.6 0.0 3.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP57202.1 - 7e-12 44.9 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 OAP57202.1 - 1.4e-09 37.6 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP57202.1 - 9.4e-09 35.3 0.1 1.8e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP57202.1 - 6.7e-08 32.9 0.0 1.2e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP57202.1 - 2.1e-06 27.5 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP57202.1 - 5.2e-06 27.0 0.0 7.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP57202.1 - 0.0051 16.2 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 OAP57202.1 - 0.036 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LRV PF01816.12 OAP57202.1 - 0.23 11.7 1.8 0.55 10.5 0.4 2.3 2 0 0 2 2 2 0 Leucine rich repeat variant K_oxygenase PF13434.1 OAP57203.1 - 2.3e-15 56.3 0.0 9e-09 34.6 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 OAP57203.1 - 5.9e-14 52.6 0.0 7.4e-06 26.1 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP57203.1 - 2.7e-06 27.3 0.0 0.11 12.4 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP57203.1 - 3.1e-06 26.3 2.0 0.017 14.0 0.5 3.5 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP57203.1 - 9.9e-05 22.1 0.6 0.085 12.6 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 OAP57203.1 - 0.00061 20.1 0.3 0.18 12.2 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP57203.1 - 0.0018 17.3 0.5 0.18 10.7 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAP57203.1 - 0.008 15.1 0.1 0.052 12.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP57203.1 - 0.0089 16.0 0.6 0.19 11.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 OAP57203.1 - 0.011 15.3 0.0 2.8 7.5 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 OAP57203.1 - 0.029 14.0 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 OAP57203.1 - 0.032 13.6 0.0 0.2 11.0 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 OAP57203.1 - 0.037 12.4 0.0 0.47 8.8 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 OAP57203.1 - 0.057 13.5 0.1 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 OAP57203.1 - 0.34 9.9 1.1 0.58 9.2 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Fungal_trans_2 PF11951.3 OAP57204.1 - 2.2e-58 197.6 0.2 4.3e-58 196.7 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57204.1 - 3.3e-05 23.7 5.9 5.7e-05 22.9 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XAP5 PF04921.9 OAP57205.1 - 1.7e-69 234.0 0.0 2.5e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.1 OAP57205.1 - 0.0051 17.0 2.1 0.0051 17.0 1.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) Death PF00531.17 OAP57206.1 - 0.21 11.3 2.1 0.28 10.9 0.4 1.9 2 0 0 2 2 2 0 Death domain DUF342 PF03961.8 OAP57206.1 - 0.54 8.6 3.2 0.71 8.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 OAP57206.1 - 0.67 10.4 4.7 0.74 10.2 2.3 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 OAP57206.1 - 0.86 7.3 5.0 1.1 7.0 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.3 OAP57206.1 - 1.3 9.0 13.6 2.3 8.2 9.4 1.3 1 0 0 1 1 1 0 YlqD protein IQ-like PF15157.1 OAP57206.1 - 2 8.7 7.0 2.3 8.4 3.0 2.4 1 1 1 2 2 2 0 IQ-like APG6 PF04111.7 OAP57206.1 - 2 7.3 11.6 2.8 6.9 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF720 PF05302.6 OAP57206.1 - 6.2 6.5 14.1 7.4 6.3 8.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF720) FAD_binding_4 PF01565.18 OAP57207.1 - 3.2e-16 59.0 0.0 5.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Fip1 PF05182.8 OAP57208.1 - 1.1e-23 82.1 1.8 2.7e-23 80.9 1.3 1.7 1 0 0 1 1 1 1 Fip1 motif DUF2890 PF11081.3 OAP57208.1 - 2 8.4 5.0 3.2 7.7 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Cpn10 PF00166.16 OAP57209.1 - 2e-26 91.7 0.0 2.2e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Vps51 PF08700.6 OAP57210.1 - 4.2e-16 58.5 3.0 1.3e-15 56.9 2.1 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 OAP57210.1 - 0.00066 19.4 0.5 0.17 11.6 0.3 2.5 2 0 0 2 2 2 2 Exocyst complex component Sec5 HemY_N PF07219.8 OAP57210.1 - 0.26 10.8 2.1 0.59 9.7 0.8 2.0 2 0 0 2 2 2 0 HemY protein N-terminus AA_permease PF00324.16 OAP57211.1 - 6.5e-132 440.2 34.9 8.1e-132 439.9 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP57211.1 - 1.4e-41 142.4 37.9 1.9e-41 141.9 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_1 PF00232.13 OAP57212.1 - 1.1e-80 271.0 1.0 1.5e-78 264.0 0.7 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 HET PF06985.6 OAP57213.1 - 1.5e-27 96.4 0.0 2.5e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC2_membrane PF01061.19 OAP57214.1 - 1.5e-88 295.4 44.4 2.7e-46 157.4 14.6 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 OAP57214.1 - 1.9e-37 128.5 0.0 1.5e-17 64.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 OAP57214.1 - 3.4e-35 119.8 0.8 1.9e-30 104.5 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 OAP57214.1 - 2.2e-17 62.9 0.1 6.2e-17 61.4 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 OAP57214.1 - 7.7e-09 35.2 0.1 8.6e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAP57214.1 - 2.9e-07 30.6 0.5 2.3e-05 24.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 OAP57214.1 - 4.1e-06 26.7 0.0 0.054 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP57214.1 - 3.3e-05 23.3 0.5 0.0041 16.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAP57214.1 - 0.00011 21.3 0.0 0.005 16.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 OAP57214.1 - 0.00018 21.0 0.8 0.0071 15.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 OAP57214.1 - 0.00018 20.7 0.0 0.47 9.6 0.0 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 OAP57214.1 - 0.00043 19.4 41.9 0.023 13.7 9.6 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.1 OAP57214.1 - 0.00053 20.1 0.1 0.4 10.8 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_21 PF13304.1 OAP57214.1 - 0.0028 17.6 0.0 1.2 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 OAP57214.1 - 0.016 14.9 0.2 7.8 6.3 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 OAP57214.1 - 0.045 13.4 0.5 3.8 7.1 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 OAP57214.1 - 0.058 14.2 0.0 4.8 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAP57214.1 - 0.061 13.6 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 OAP57214.1 - 0.097 12.9 0.0 0.73 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 OAP57214.1 - 0.13 11.9 0.5 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 OAP57214.1 - 0.17 11.2 1.7 5.4 6.3 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 OAP57214.1 - 0.35 10.3 1.3 13 5.1 0.0 3.3 4 0 0 4 4 3 0 FtsK/SpoIIIE family DUF566 PF04484.7 OAP57216.1 - 1 8.7 16.1 1.4 8.3 11.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3425 PF11905.3 OAP57217.1 - 9.1e-17 61.2 0.0 2.3e-16 59.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP57217.1 - 0.00047 20.0 12.4 0.0021 17.9 8.6 2.0 1 1 0 1 1 1 1 bZIP transcription factor DUF1366 PF07104.6 OAP57217.1 - 0.14 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Ubiquitin_2 PF14560.1 OAP57217.1 - 0.16 12.2 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain bZIP_2 PF07716.10 OAP57217.1 - 0.17 11.7 9.1 0.17 11.7 1.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Pyr_redox_3 PF13738.1 OAP57218.1 - 2.4e-22 80.0 0.0 4e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP57218.1 - 2.1e-16 59.2 0.8 8.5e-15 53.9 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP57218.1 - 1.3e-10 41.1 0.0 2.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP57218.1 - 5.2e-05 22.3 0.1 0.0032 16.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP57218.1 - 0.00056 19.7 0.1 0.026 14.3 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAP57218.1 - 0.0054 15.8 0.0 0.038 13.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family adh_short PF00106.20 OAP57219.1 - 2e-27 96.1 0.5 2.9e-27 95.6 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57219.1 - 2.9e-20 73.0 0.0 3.4e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP57219.1 - 7.2e-07 29.0 0.3 1.5e-06 27.9 0.2 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP57219.1 - 0.0032 17.1 0.3 0.0083 15.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP57219.1 - 0.011 15.1 0.0 0.08 12.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 OAP57219.1 - 0.033 13.2 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TRI12 PF06609.8 OAP57220.1 - 1.1e-32 112.9 29.8 1.5e-32 112.6 20.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP57220.1 - 2.7e-19 69.1 53.0 2.7e-19 69.1 36.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_oxidored PF12831.2 OAP57221.1 - 6.9e-71 239.5 5.8 6e-70 236.4 4.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP57221.1 - 6.4e-07 28.5 5.2 1.5e-05 24.0 1.4 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 OAP57221.1 - 2.3e-05 24.3 0.1 3.7e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP57221.1 - 6.8e-05 23.2 0.3 0.00015 22.1 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP57221.1 - 7.8e-05 21.7 0.3 0.00011 21.1 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 OAP57221.1 - 0.00014 20.9 2.1 0.00027 19.9 1.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP57221.1 - 0.004 17.1 3.2 0.005 16.8 0.6 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP57221.1 - 0.016 13.6 0.3 0.026 12.9 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 OAP57221.1 - 0.067 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 OAP57221.1 - 0.27 10.1 2.8 1.2 8.0 0.5 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HET PF06985.6 OAP57222.1 - 5.2e-05 23.4 0.5 0.00025 21.2 0.0 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ost4 PF10215.4 OAP57223.1 - 3.9e-18 64.6 1.8 5.5e-18 64.1 1.3 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase BTV_NS2 PF04514.7 OAP57223.1 - 0.23 10.3 4.7 0.28 10.0 3.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Psb28 PF03912.9 OAP57225.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Psb28 protein KOW PF00467.24 OAP57226.1 - 1e-07 31.3 0.3 1e-07 31.3 0.2 2.0 2 0 0 2 2 2 1 KOW motif MIP PF00230.15 OAP57227.1 - 5.2e-29 101.3 6.7 7.7e-29 100.7 4.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein adh_short PF00106.20 OAP57228.1 - 2.1e-18 66.7 0.9 2.7e-18 66.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57228.1 - 2.1e-09 37.3 0.3 2.6e-09 36.9 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP57228.1 - 2.1e-08 34.2 0.0 2.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF460 PF04312.8 OAP57228.1 - 0.0086 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF460) DUF4396 PF14342.1 OAP57229.1 - 7.3e-35 120.0 11.9 1.5e-34 119.0 8.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Fungal_trans_2 PF11951.3 OAP57230.1 - 0.00018 20.2 0.0 0.002 16.8 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Acyltransferase PF01553.16 OAP57231.1 - 7.3e-17 61.0 0.0 1.9e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase HK PF02110.10 OAP57231.1 - 0.021 13.9 0.0 0.33 10.0 0.0 2.2 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Peptidase_M24 PF00557.19 OAP57234.1 - 4.4e-21 75.4 0.0 5.1e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 LRR_9 PF14580.1 OAP57235.1 - 3.6e-54 182.9 0.1 5e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 OAP57235.1 - 1.6e-08 34.1 3.7 4.4e-07 29.5 0.1 3.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 OAP57235.1 - 3.8e-08 32.7 3.8 2.4e-05 23.8 0.1 4.5 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) DUF1542 PF07564.6 OAP57235.1 - 0.14 12.2 0.9 0.27 11.2 0.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) LRR_7 PF13504.1 OAP57235.1 - 0.19 12.0 6.1 21 5.8 0.1 5.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 OAP57235.1 - 0.36 11.0 2.4 10 6.5 0.0 3.8 3 1 1 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 OAP57235.1 - 2.2 8.6 10.1 23 5.5 0.1 5.1 6 1 0 6 6 6 0 Leucine Rich Repeat GATase PF00117.23 OAP57236.1 - 2e-09 37.1 0.0 3.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 OAP57236.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.11 OAP57237.1 - 9.3e-31 106.8 35.9 2.1e-30 105.6 23.3 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP57237.1 - 9.3e-05 21.1 8.1 9.3e-05 21.1 5.6 3.2 3 1 1 4 4 4 2 Sugar (and other) transporter TPP_enzyme_N PF02776.13 OAP57238.1 - 3.4e-38 130.8 0.6 5.3e-38 130.1 0.4 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAP57238.1 - 8.4e-16 57.8 0.6 1.9e-11 43.7 0.1 3.3 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP57238.1 - 9.8e-12 44.8 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Na_Ca_ex PF01699.19 OAP57239.1 - 1.6e-43 147.6 30.9 2e-22 79.2 8.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ATP_bind_3 PF01171.15 OAP57240.1 - 4.6e-36 124.0 0.4 5.3e-35 120.5 0.2 2.3 1 1 0 1 1 1 1 PP-loop family DIOX_N PF14226.1 OAP57241.1 - 2.8e-15 56.8 0.0 4.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP57241.1 - 1.3e-13 51.0 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRN3 PF05327.6 OAP57242.1 - 4.2e-142 474.1 0.3 5e-142 473.9 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SIMPL PF04402.9 OAP57243.1 - 3.3e-21 76.1 0.1 5.5e-21 75.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF541) Sugar_tr PF00083.19 OAP57244.1 - 1.2e-77 261.4 24.6 1.4e-77 261.2 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57244.1 - 6.2e-24 84.3 55.3 1.7e-22 79.6 21.4 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF3425 PF11905.3 OAP57245.1 - 3.9e-19 68.8 12.2 1.2e-18 67.3 8.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) NmrA PF05368.8 OAP57246.1 - 1.8e-31 109.1 0.0 2.9e-31 108.5 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP57246.1 - 3e-08 33.8 0.0 4.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP57246.1 - 9.1e-05 21.9 0.0 0.00029 20.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 OAP57246.1 - 0.00026 20.9 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 OAP57246.1 - 0.00048 18.9 0.0 0.00067 18.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAP57246.1 - 0.00084 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57246.1 - 0.043 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 OAP57246.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 OAP57246.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Xan_ur_permease PF00860.15 OAP57247.1 - 4.4e-22 78.1 24.2 2e-21 75.9 16.8 2.0 1 1 0 1 1 1 1 Permease family DUF973 PF06157.6 OAP57247.1 - 3.1 6.7 9.1 0.067 12.1 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Methyltransf_11 PF08241.7 OAP57248.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAP57248.1 - 0.055 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fcf1 PF04900.7 OAP57249.1 - 8.5e-10 38.6 0.7 3.3e-06 27.1 0.4 3.1 2 1 0 2 2 2 2 Fcf1 Tmemb_14 PF03647.8 OAP57250.1 - 2e-24 85.8 7.3 2.4e-24 85.5 5.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 OAP57250.1 - 0.00027 21.1 1.1 0.00052 20.2 0.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) GMC_oxred_N PF00732.14 OAP57251.1 - 1.4e-55 188.5 0.0 2e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP57251.1 - 9.3e-36 123.2 0.0 1.7e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAP57251.1 - 1.5e-05 24.8 0.1 3.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP57251.1 - 0.026 13.4 0.3 0.045 12.6 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 OAP57251.1 - 0.038 12.9 3.2 0.022 13.7 0.8 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP57251.1 - 0.076 11.8 5.0 0.018 13.9 1.3 1.5 2 0 0 2 2 2 0 FAD binding domain DAD PF02109.11 OAP57252.1 - 1.9e-39 134.2 0.7 1.6e-37 128.0 0.5 2.0 1 1 0 1 1 1 1 DAD family SET PF00856.23 OAP57253.1 - 2.4e-07 31.1 0.0 2.3e-06 28.0 0.0 2.4 1 1 0 1 1 1 1 SET domain Fungal_trans PF04082.13 OAP57254.1 - 8.3e-56 188.7 0.0 1.3e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP57254.1 - 0.00014 21.9 13.9 0.0018 18.4 2.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP57254.1 - 0.00099 19.2 9.7 0.0024 18.0 1.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP57254.1 - 0.0033 17.6 2.4 0.0033 17.6 1.7 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger GFA PF04828.9 OAP57255.1 - 7.8e-07 28.9 0.1 7.8e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 OAP57255.1 - 0.029 14.2 2.2 0.043 13.7 0.4 1.9 2 0 0 2 2 2 0 Cysteine-rich CWC Rot1 PF10681.4 OAP57256.1 - 9.1e-92 306.2 0.4 1.1e-91 305.9 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.15 OAP57257.1 - 2.3e-35 122.0 0.0 3.1e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 OAP57258.1 - 8e-15 54.1 0.1 1e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 OAP57258.1 - 0.042 13.2 0.3 0.28 10.6 0.0 2.2 3 0 0 3 3 3 0 PhnA protein Xpo1 PF08389.7 OAP57259.1 - 6e-27 94.3 0.3 1.4e-25 89.9 0.0 3.4 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 OAP57259.1 - 2.1e-07 30.7 0.8 2.7e-06 27.2 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 OAP57259.1 - 0.0006 20.0 1.0 0.39 11.0 0.0 4.9 3 2 4 7 7 7 2 HEAT repeats Mito_carr PF00153.22 OAP57260.1 - 3.1e-54 180.6 2.2 2.4e-20 72.0 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-ZPR1 PF03367.8 OAP57261.1 - 1.4e-99 329.9 0.0 3.6e-51 172.5 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain E7 PF00527.13 OAP57261.1 - 0.011 15.8 1.2 0.77 9.9 0.1 2.8 2 0 0 2 2 2 0 E7 protein, Early protein UPF0547 PF10571.4 OAP57261.1 - 0.032 13.9 9.0 0.91 9.2 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 OAP57261.1 - 0.035 13.3 6.3 0.059 12.5 1.9 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 OAP57261.1 - 0.1 12.9 4.1 0.69 10.2 0.8 2.8 3 0 0 3 3 3 0 Restriction alleviation protein Lar HypA PF01155.14 OAP57261.1 - 0.12 12.0 2.7 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 OAP57261.1 - 0.47 10.5 7.1 4.6 7.3 0.6 3.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Elf1 PF05129.8 OAP57261.1 - 0.5 10.0 5.6 6.4 6.5 1.2 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.1 OAP57261.1 - 2 8.0 8.0 3.8 7.1 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 OAP57261.1 - 2.5 7.9 9.0 26 4.7 2.8 3.5 3 1 0 3 3 3 0 Double zinc ribbon Rpr2 PF04032.11 OAP57262.1 - 9.1e-06 25.4 1.1 2.5e-05 24.0 0.7 1.8 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain PLATZ PF04640.9 OAP57262.1 - 0.025 14.7 3.6 6.2 7.1 0.0 3.2 1 1 1 2 2 2 0 PLATZ transcription factor RNA_POL_M_15KD PF02150.11 OAP57262.1 - 0.16 11.6 0.1 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Fungal_trans_2 PF11951.3 OAP57263.1 - 1.3e-07 30.6 0.4 0.0017 17.0 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Cwf_Cwc_15 PF04889.7 OAP57263.1 - 5.5 6.6 8.0 8.9 5.9 5.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein bZIP_1 PF00170.16 OAP57264.1 - 1.4e-10 40.9 10.3 4.9e-10 39.2 4.8 2.4 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.10 OAP57264.1 - 0.0016 18.1 9.7 0.025 14.3 3.6 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 OAP57264.1 - 0.0026 18.0 8.0 0.0043 17.3 5.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor CCDC92 PF14916.1 OAP57264.1 - 0.0087 15.6 2.2 0.023 14.2 1.5 1.7 1 0 0 1 1 1 1 Coiled-coil domain of unknown function DUF2400 PF09674.5 OAP57264.1 - 0.054 13.1 0.6 0.081 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Rhabdo_M1 PF03342.8 OAP57264.1 - 0.067 12.3 2.1 0.089 11.9 1.5 1.1 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) TMF_TATA_bd PF12325.3 OAP57264.1 - 0.23 11.2 4.2 0.19 11.4 1.9 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 OAP57264.1 - 0.31 10.5 3.7 0.47 10.0 2.6 1.3 1 0 0 1 1 1 0 IncA protein adh_short PF00106.20 OAP57265.1 - 7.1e-13 48.8 0.5 1.3e-12 47.9 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57265.1 - 0.00017 21.3 0.1 0.00031 20.4 0.1 1.4 1 0 0 1 1 1 1 KR domain DBR1 PF05011.8 OAP57266.1 - 3.9e-43 146.8 0.0 7.6e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 OAP57266.1 - 5.9e-07 29.0 2.0 1e-06 28.3 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ORC6 PF05460.8 OAP57267.1 - 4e-36 124.8 0.0 9.3e-31 107.1 1.1 2.0 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Ribosomal_60s PF00428.14 OAP57267.1 - 0.022 15.1 0.2 0.1 13.0 0.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.8 OAP57267.1 - 1.2 9.0 11.4 5 6.9 7.9 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myc_N PF01056.13 OAP57267.1 - 1.2 8.2 9.2 0.07 12.2 2.7 1.5 2 0 0 2 2 2 0 Myc amino-terminal region Nucleoplasmin PF03066.10 OAP57267.1 - 2 7.9 8.2 5.2 6.5 5.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin Methyltransf_24 PF13578.1 OAP57269.1 - 1.2e-11 45.3 0.0 2.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 OAP57269.1 - 1.5e-05 24.1 0.1 3.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 OAP57269.1 - 0.0017 18.8 0.0 0.0029 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_101 PF12905.2 OAP57269.1 - 0.031 12.8 0.0 0.079 11.5 0.0 1.5 1 1 1 2 2 2 0 Endo-alpha-N-acetylgalactosaminidase GTP_EFTU_D4 PF14578.1 OAP57269.1 - 0.086 12.4 1.2 0.12 11.9 0.8 1.2 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Peptidase_C14 PF00656.17 OAP57270.1 - 9.1e-06 25.5 0.0 1.8e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 OAP57270.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF1837 PF08878.6 OAP57270.1 - 0.088 12.3 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1837) SF3a60_bindingd PF12108.3 OAP57270.1 - 7.1 6.2 7.8 35 4.0 2.4 2.5 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain PfkB PF00294.19 OAP57271.1 - 3.1e-35 121.7 0.0 3e-32 111.9 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase IU_nuc_hydro PF01156.14 OAP57272.1 - 5e-81 272.3 0.0 5.6e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase AA_permease_2 PF13520.1 OAP57273.1 - 6.8e-62 209.3 54.7 8.5e-62 209.0 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP57273.1 - 2.4e-20 72.3 45.8 3.3e-20 71.8 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease Amidohydro_1 PF01979.15 OAP57274.1 - 9.8e-38 130.6 0.8 1.3e-37 130.1 0.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 OAP57274.1 - 7.6e-07 28.6 1.4 0.00011 21.5 0.1 2.7 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP57274.1 - 0.00035 20.3 0.1 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 OAP57274.1 - 0.0019 18.3 0.1 0.89 9.5 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase Transpep_BrtH PF14399.1 OAP57274.1 - 0.057 12.7 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase 2OG-FeII_Oxy PF03171.15 OAP57275.1 - 7.7e-05 22.9 0.0 0.00022 21.4 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_16 PF00722.16 OAP57276.1 - 8.5e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2070 PF09843.4 OAP57276.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HORMA PF02301.13 OAP57277.1 - 5.9e-21 74.9 0.0 7.7e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Ceramidase PF05875.7 OAP57278.1 - 4e-100 334.2 13.5 4.9e-100 334.0 9.3 1.1 1 0 0 1 1 1 1 Ceramidase Reticulon PF02453.12 OAP57278.1 - 0.0098 15.5 0.1 0.022 14.3 0.1 1.5 1 0 0 1 1 1 1 Reticulon DUF788 PF05620.6 OAP57278.1 - 0.059 13.2 1.3 0.16 11.8 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Prefoldin_2 PF01920.15 OAP57279.1 - 3.6e-16 58.8 6.2 4.7e-16 58.4 4.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Mod_r PF07200.8 OAP57279.1 - 0.024 14.5 2.6 0.024 14.5 0.1 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CMS1 PF14617.1 OAP57279.1 - 0.053 12.5 0.6 0.063 12.3 0.4 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Rootletin PF15035.1 OAP57279.1 - 0.055 13.4 0.5 0.055 13.4 0.3 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SurA_N PF09312.6 OAP57279.1 - 0.057 13.2 1.1 0.16 11.8 0.8 1.8 1 1 0 1 1 1 0 SurA N-terminal domain DUF2982 PF11201.3 OAP57279.1 - 0.14 11.5 1.0 0.2 11.0 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2982) ADIP PF11559.3 OAP57279.1 - 0.18 11.7 8.0 0.3 10.9 0.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 OAP57279.1 - 0.61 10.5 4.9 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 SlyX Fib_alpha PF08702.5 OAP57279.1 - 6 6.9 8.7 3.3 7.8 0.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family VGCC_beta4Aa_N PF12052.3 OAP57280.1 - 0.87 9.5 14.0 3.2 7.7 2.9 3.3 1 1 1 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal CAF-1_p150 PF11600.3 OAP57280.1 - 7.1 5.9 51.6 12 5.1 35.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neurensin PF14927.1 OAP57282.1 - 0.18 11.1 0.9 0.42 9.9 0.1 2.0 1 1 1 2 2 2 0 Neurensin DUF3007 PF11460.3 OAP57282.1 - 1.3 9.1 3.5 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Peptidase_U4 PF03419.8 OAP57282.1 - 2.5 7.0 12.3 3.3 6.6 8.5 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DEAD PF00270.24 OAP57284.1 - 4.2e-26 91.4 0.0 9.5e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 OAP57284.1 - 7.2e-13 48.9 0.3 1.7e-12 47.7 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 OAP57284.1 - 6e-09 35.6 0.1 2.2e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP57284.1 - 2.2e-05 24.3 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.6 OAP57284.1 - 3.7e-05 23.7 0.0 8.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like IBR PF01485.16 OAP57285.1 - 8.2e-07 28.8 7.2 8.2e-07 28.8 5.0 3.5 3 1 0 3 3 3 2 IBR domain Acetyltransf_7 PF13508.1 OAP57286.1 - 4.7e-08 33.0 0.0 1.5e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP57286.1 - 1.2e-07 31.6 0.2 2.4e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP57286.1 - 6.1e-05 22.9 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP57286.1 - 0.00018 21.6 0.1 0.00052 20.1 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP57286.1 - 0.00027 20.7 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase FR47 PF08445.5 OAP57286.1 - 0.0058 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Pyr_redox_3 PF13738.1 OAP57287.1 - 2.2e-21 76.8 0.0 4.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP57287.1 - 2.3e-20 72.2 0.8 1.5e-17 63.0 0.3 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP57287.1 - 2.6e-09 36.4 0.0 8.6e-07 28.1 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP57287.1 - 1.4e-07 31.4 0.0 3.5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP57287.1 - 0.0014 18.4 0.6 0.093 12.4 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 OAP57287.1 - 0.021 14.5 0.0 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 OAP57287.1 - 0.033 14.0 0.1 8 6.2 0.1 2.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP57287.1 - 0.15 11.1 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Thi4 family XPC-binding PF09280.6 OAP57287.1 - 0.2 11.1 0.7 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 XPC-binding domain MMR_HSR1 PF01926.18 OAP57288.1 - 2.1e-07 30.8 0.0 7.1e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAP57288.1 - 4.6e-05 22.6 0.0 0.00012 21.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAP57288.1 - 0.00018 20.6 1.2 1.2 8.2 0.0 3.8 4 0 0 4 4 4 2 AIG1 family AAA_29 PF13555.1 OAP57288.1 - 0.00057 19.3 0.0 0.0016 17.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAP57288.1 - 0.00067 19.6 0.0 0.0036 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.13 OAP57288.1 - 0.0074 15.3 0.1 0.038 13.0 0.1 2.2 1 1 0 1 1 1 1 Septin T2SE PF00437.15 OAP57288.1 - 0.012 14.4 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 OAP57288.1 - 0.014 14.8 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 OAP57288.1 - 0.014 15.1 0.1 0.35 10.6 0.1 2.9 1 1 0 1 1 1 0 Dynamin family Mg_chelatase PF01078.16 OAP57288.1 - 0.018 14.2 0.1 0.1 11.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MutS_III PF05192.13 OAP57288.1 - 0.035 13.8 4.0 3.1 7.5 0.1 3.4 3 1 0 3 3 3 0 MutS domain III NACHT PF05729.7 OAP57288.1 - 0.041 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.22 OAP57288.1 - 0.054 12.9 0.6 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAP57288.1 - 0.062 13.4 0.1 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 OAP57288.1 - 0.071 13.3 2.1 0.26 11.5 0.0 2.9 3 0 0 3 3 3 0 ABC transporter AAA_10 PF12846.2 OAP57288.1 - 0.099 12.0 2.6 0.13 11.7 0.0 2.5 4 0 0 4 4 4 0 AAA-like domain MobB PF03205.9 OAP57288.1 - 0.16 11.6 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 OAP57288.1 - 0.43 10.8 11.4 0.79 10.0 2.2 3.3 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 OAP57288.1 - 3.5 7.3 7.3 1.9 8.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 Oxidored-like PF09791.4 OAP57289.1 - 5.8e-26 89.6 4.8 1.1e-25 88.8 3.3 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Glyoxalase_2 PF12681.2 OAP57290.1 - 1.9e-11 44.5 0.1 4.5e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP57290.1 - 2.5e-06 27.4 0.0 5.7e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 OAP57290.1 - 0.011 15.6 0.0 0.17 11.9 0.0 2.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2388 PF09498.5 OAP57290.1 - 0.065 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) DUF904 PF06005.7 OAP57291.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) MFS_1 PF07690.11 OAP57293.1 - 4.3e-14 51.9 33.4 4.3e-14 51.9 23.2 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP57293.1 - 5.3e-07 28.5 11.6 5.3e-07 28.5 8.0 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.13 OAP57294.1 - 3.3e-28 98.2 0.4 5.9e-28 97.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 OAP57295.1 - 6e-19 68.3 0.1 3.8e-18 65.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP57295.1 - 3.2e-12 46.0 2.0 1.5e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP57295.1 - 9.2e-07 28.0 2.4 8.9e-06 24.7 1.5 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP57295.1 - 1.6e-06 28.1 0.5 4.2e-06 26.7 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP57295.1 - 3e-06 27.1 0.7 2.3e-05 24.2 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 OAP57295.1 - 1e-05 24.8 0.4 1.7e-05 24.0 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP57295.1 - 3.7e-05 22.3 0.8 0.00025 19.6 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 OAP57295.1 - 9.5e-05 21.4 0.2 0.021 13.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 OAP57295.1 - 0.00022 20.8 0.6 0.00037 20.0 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 OAP57295.1 - 0.0012 19.2 1.2 0.0025 18.1 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP57295.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP57295.1 - 0.0041 16.0 2.3 0.0042 15.9 0.8 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 OAP57295.1 - 0.0047 15.6 3.5 0.02 13.5 0.7 2.5 2 1 1 3 3 3 1 Tryptophan halogenase 3HCDH_N PF02737.13 OAP57295.1 - 0.031 13.9 0.3 0.056 13.1 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 OAP57295.1 - 0.033 12.4 0.4 0.047 11.9 0.3 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Thi4 PF01946.12 OAP57295.1 - 0.05 12.6 0.4 0.092 11.8 0.3 1.3 1 0 0 1 1 1 0 Thi4 family Methyltransf_18 PF12847.2 OAP57295.1 - 0.068 13.7 0.0 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain FAD_binding_3 PF01494.14 OAP57296.1 - 7.1e-92 308.1 0.0 8.7e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP57296.1 - 6.5e-06 26.1 0.0 2.5e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP57296.1 - 0.0038 16.1 0.1 0.023 13.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 OAP57296.1 - 0.0064 15.4 1.8 0.15 10.9 0.4 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP57296.1 - 0.007 15.4 0.1 0.015 14.4 0.0 1.6 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 OAP57296.1 - 0.022 14.7 0.2 0.05 13.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 OAP57296.1 - 0.039 12.8 0.1 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAP57296.1 - 0.12 12.4 0.1 0.5 10.3 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAP57296.1 - 0.13 12.2 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 OAP57296.1 - 0.28 9.6 0.2 1 7.7 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Glyoxalase PF00903.20 OAP57297.1 - 3.1e-12 46.5 4.2 3.2e-11 43.3 1.3 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP57297.1 - 1.4e-07 32.1 2.0 0.00026 21.5 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain p450 PF00067.17 OAP57298.1 - 2.1e-55 188.1 0.0 2.6e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 OAP57299.1 - 9.4e-21 74.4 0.1 2.4e-20 73.1 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57299.1 - 3.7e-18 66.1 0.5 6.2e-18 65.4 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP57299.1 - 4.9e-12 45.8 1.1 2.1e-10 40.5 0.8 2.1 1 1 0 1 1 1 1 KR domain Pyr_redox PF00070.22 OAP57299.1 - 0.0026 18.1 0.1 0.023 15.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_tran_WecB PF03808.8 OAP57299.1 - 0.02 14.3 0.1 1.2 8.4 0.0 2.4 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.10 OAP57299.1 - 0.026 13.4 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 OAP57299.1 - 0.033 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAD_binding_3 PF01494.14 OAP57299.1 - 0.035 13.1 0.1 0.068 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Epimerase PF01370.16 OAP57299.1 - 0.044 13.2 0.1 0.098 12.0 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAP57299.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 OAP57299.1 - 0.21 11.5 2.0 8.5 6.3 1.4 2.5 1 1 0 1 1 1 0 NADH(P)-binding ECH PF00378.15 OAP57300.1 - 8.6e-44 149.4 0.0 1e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Lipase_3 PF01764.20 OAP57300.1 - 0.047 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) UPF0160 PF03690.8 OAP57301.1 - 2.2e-117 392.0 0.0 2.5e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) L_biotic_typeA PF04604.8 OAP57301.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Type-A lantibiotic ICE2 PF08426.5 OAP57302.1 - 4.8e-128 427.2 8.6 5.6e-128 427.0 6.0 1.0 1 0 0 1 1 1 1 ICE2 Endosulfine PF04667.12 OAP57303.1 - 4.3e-22 77.8 0.1 4.3e-22 77.8 0.1 1.6 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 OAP57304.1 - 2.5e-44 151.0 0.0 3.3e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Fungal_trans_2 PF11951.3 OAP57305.1 - 3.5e-07 29.1 0.4 5.6e-07 28.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Adaptin_binding PF10199.4 OAP57305.1 - 0.13 12.5 0.0 0.96 9.7 0.0 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Pribosyltran PF00156.22 OAP57306.1 - 4.2e-10 39.4 0.1 1.4e-09 37.7 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain zf-C2H2 PF00096.21 OAP57308.1 - 7.2e-19 66.9 29.0 0.0002 21.5 0.1 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP57308.1 - 9.9e-14 50.5 26.9 0.0022 18.2 0.2 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP57308.1 - 7.9e-08 32.2 33.4 0.017 15.3 0.2 6.0 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAP57308.1 - 0.00076 19.5 6.5 0.3 11.2 0.0 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 OAP57308.1 - 0.028 14.4 6.2 9.3 6.3 0.1 4.6 4 0 0 4 4 4 0 zinc-finger zf-C2H2_6 PF13912.1 OAP57308.1 - 0.044 13.6 21.5 0.73 9.8 0.1 5.3 4 1 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 OAP57308.1 - 0.47 10.1 15.4 0.25 11.0 2.2 4.5 4 2 0 4 4 4 0 zinc-ribbon domain XPA_N PF01286.13 OAP57308.1 - 0.49 10.1 5.7 2.7 7.7 0.2 3.7 4 0 0 4 4 4 0 XPA protein N-terminal Ribosomal_S27 PF01599.14 OAP57308.1 - 1 9.2 13.9 4.1 7.2 1.4 3.3 2 2 0 2 2 2 0 Ribosomal protein S27a zinc_ribbon_5 PF13719.1 OAP57308.1 - 1 8.9 15.9 0.27 10.8 2.3 4.4 4 2 0 4 4 4 0 zinc-ribbon domain zf-Di19 PF05605.7 OAP57308.1 - 1.8 8.7 26.0 0.051 13.6 1.7 4.8 3 1 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 OAP57308.1 - 2.3 8.4 0.0 2.3 8.4 0.0 4.4 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) A2L_zn_ribbon PF08792.5 OAP57308.1 - 2.4 7.7 9.6 19 4.8 0.1 4.2 4 0 0 4 4 4 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 OAP57308.1 - 3.2 7.7 23.0 1.6 8.7 0.4 4.8 3 1 1 4 4 4 0 Zinc ribbon domain zf-LYAR PF08790.6 OAP57308.1 - 5.9 6.6 12.2 32 4.3 0.0 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger RRN7 PF11781.3 OAP57308.1 - 8 6.0 9.5 48 3.5 0.1 4.2 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ion_trans PF00520.26 OAP57309.1 - 0.0007 18.9 11.9 0.0007 18.9 8.2 2.0 1 1 1 2 2 2 1 Ion transport protein DUF1989 PF09347.5 OAP57310.1 - 6.7e-28 97.2 0.0 1.5e-27 96.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) Rhomboid PF01694.17 OAP57311.1 - 2.6e-34 118.3 11.7 2.6e-34 118.3 8.1 2.0 2 0 0 2 2 2 1 Rhomboid family DUF3317 PF11779.3 OAP57312.1 - 3.3e-16 58.4 2.2 5.8e-16 57.6 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF2953 PF11167.3 OAP57312.1 - 0.0088 15.9 0.9 0.034 14.0 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2953) DUF4414 PF14377.1 OAP57313.1 - 5.8 6.8 9.9 71 3.3 6.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) AMP-binding PF00501.23 OAP57314.1 - 8.5e-58 195.6 0.0 1.4e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP57314.1 - 2.1e-08 34.9 0.0 4.8e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DASH_Dad3 PF08656.5 OAP57315.1 - 2.2e-19 68.9 0.5 5e-13 48.5 0.1 2.2 2 0 0 2 2 2 2 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.10 OAP57316.1 - 6.5e-19 67.0 0.0 1.8e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 OAP57316.1 - 2e-09 37.0 0.1 4.9e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain LZ_Tnp_IS481 PF13011.1 OAP57316.1 - 0.62 10.4 3.0 2.7 8.3 0.1 2.8 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 PRMT5 PF05185.11 OAP57317.1 - 4.9e-164 546.4 0.0 8.8e-163 542.3 0.0 2.3 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase GDPD PF03009.12 OAP57318.1 - 2.2e-74 250.2 0.0 4.5e-74 249.1 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 OAP57318.1 - 2.5e-33 114.2 0.2 4.7e-17 62.0 0.1 4.4 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP57318.1 - 1e-32 111.9 2.7 6.5e-13 48.8 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 OAP57318.1 - 3.3e-30 102.3 2.9 1.3e-07 31.0 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat SPX PF03105.14 OAP57318.1 - 1.3e-29 103.8 4.1 5.7e-16 59.1 1.2 3.4 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 OAP57318.1 - 1.3e-20 72.9 3.0 2.2e-08 34.0 0.0 6.2 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP57318.1 - 4.3e-20 69.8 5.3 9.4e-06 25.3 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Pkinase PF00069.20 OAP57319.1 - 4.6e-72 242.2 0.0 4.1e-71 239.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP57319.1 - 3.4e-31 108.2 0.0 9.7e-23 80.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAP57319.1 - 1.4e-06 27.5 0.2 0.15 10.9 0.0 3.1 2 1 0 3 3 3 3 Kinase-like Kdo PF06293.9 OAP57319.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vps4_C PF09336.5 OAP57320.1 - 0.017 14.9 0.1 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain His_Phos_2 PF00328.17 OAP57321.1 - 1.2e-13 51.1 0.0 2.4e-13 50.1 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.1 OAP57321.1 - 0.053 13.1 0.3 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 PDGLE domain TRF PF08558.5 OAP57322.1 - 1.6e-48 165.1 0.0 1.3e-47 162.1 0.0 2.1 2 0 0 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 OAP57322.1 - 4.6e-06 26.5 0.1 6.5e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAP57322.1 - 0.027 14.5 0.2 0.09 12.8 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain TFIID_30kDa PF03540.8 OAP57323.1 - 2.9e-21 75.0 0.7 7.7e-21 73.6 0.5 1.7 1 1 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 OAP57323.1 - 0.27 11.7 4.4 0.99 9.8 3.0 2.0 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.16 OAP57324.1 - 8e-20 70.2 0.0 9.6e-20 69.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ras PF00071.17 OAP57325.1 - 1.7e-56 190.1 0.1 2.1e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP57325.1 - 2.6e-21 76.3 0.1 3.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP57325.1 - 1.5e-17 63.4 0.1 1.7e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAP57325.1 - 4.3e-08 32.8 0.0 1.8e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAP57325.1 - 1.4e-06 27.6 0.1 1.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 OAP57325.1 - 3.2e-06 26.4 0.0 4.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 OAP57325.1 - 1.9e-05 24.5 0.0 3.1e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 OAP57325.1 - 0.06 13.3 0.0 1.4 8.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 OAP57325.1 - 0.074 12.8 0.0 2.9 7.6 0.0 2.4 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 OAP57325.1 - 0.11 12.0 0.3 0.41 10.1 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 OAP57325.1 - 0.14 12.3 0.0 1.7 8.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain PBP PF01161.15 OAP57326.1 - 1.6e-14 53.9 0.2 2e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PPR_2 PF13041.1 OAP57327.1 - 4.5e-46 154.6 9.3 4.3e-12 45.8 0.0 11.9 10 4 4 14 14 14 9 PPR repeat family PPR_3 PF13812.1 OAP57327.1 - 5.6e-27 91.7 14.8 0.018 15.3 0.0 14.5 16 0 0 16 16 16 6 Pentatricopeptide repeat domain PPR PF01535.15 OAP57327.1 - 1.1e-22 78.3 12.5 0.0011 18.8 0.0 12.9 15 1 0 15 15 15 5 PPR repeat PPR_1 PF12854.2 OAP57327.1 - 5.7e-19 67.2 0.0 5.7e-07 28.8 0.0 8.7 9 0 0 9 9 9 3 PPR repeat RPM2 PF08579.6 OAP57327.1 - 0.0011 19.1 0.0 1.4 9.0 0.0 4.3 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) BTAD PF03704.12 OAP57327.1 - 0.014 15.7 6.1 5.3 7.3 0.0 4.6 4 1 1 5 5 5 0 Bacterial transcriptional activator domain TPR_14 PF13428.1 OAP57327.1 - 0.075 13.7 16.6 19 6.2 0.1 8.5 7 2 4 11 11 11 0 Tetratricopeptide repeat PNPOx_C PF10590.4 OAP57328.1 - 9.7e-22 76.1 1.3 2.2e-21 75.0 0.9 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 OAP57328.1 - 1.3e-15 57.1 0.0 2.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 OAP57328.1 - 0.0034 17.6 0.1 0.0088 16.3 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EF-hand_1 PF00036.27 OAP57329.1 - 1e-40 133.9 8.3 8.8e-10 37.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAP57329.1 - 1.5e-33 114.7 8.5 2.9e-17 62.5 1.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAP57329.1 - 1.8e-31 107.4 8.0 2.9e-14 52.4 0.3 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 OAP57329.1 - 2.8e-31 104.5 4.8 4.4e-09 35.4 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAP57329.1 - 2.6e-26 89.7 11.1 3.4e-08 32.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 OAP57329.1 - 2.9e-15 55.9 0.2 5.5e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 OAP57329.1 - 1.3e-09 37.7 3.3 5.4e-05 22.8 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 OAP57329.1 - 2.5e-07 30.2 0.5 0.036 13.6 0.0 2.9 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 OAP57329.1 - 2.8e-07 30.5 0.1 0.0092 15.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.1 OAP57329.1 - 0.00012 22.3 1.4 0.037 14.3 0.0 2.7 1 1 1 2 2 2 1 Toprim-like TerB PF05099.8 OAP57329.1 - 0.00018 21.2 0.7 0.075 12.7 0.0 2.6 1 1 2 3 3 3 1 Tellurite resistance protein TerB PMBR PF09373.5 OAP57329.1 - 0.0093 15.8 0.1 41 4.3 0.0 3.9 4 0 0 4 4 3 0 Pseudomurein-binding repeat RNA_pol_Rpb4 PF03874.11 OAP57329.1 - 0.011 15.7 1.8 2.2 8.3 0.2 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 OAP57329.1 - 0.016 14.7 0.3 0.83 9.1 0.0 2.4 2 1 0 2 2 2 0 Tenuivirus major non-capsid protein DUF1002 PF06207.6 OAP57329.1 - 0.019 14.2 0.9 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) FlgD PF03963.9 OAP57329.1 - 0.027 14.5 1.0 0.55 10.3 0.2 2.4 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region EF-hand_10 PF14788.1 OAP57329.1 - 0.032 13.8 6.5 0.093 12.4 0.3 3.8 2 2 2 4 4 4 0 EF hand DUF3164 PF11363.3 OAP57329.1 - 0.034 13.5 0.4 0.74 9.1 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3164) DUF1456 PF07308.8 OAP57329.1 - 0.048 13.7 0.8 2.1 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) YqeY PF09424.5 OAP57329.1 - 0.05 13.4 0.2 0.61 9.9 0.0 2.0 1 1 1 2 2 2 0 Yqey-like protein Caleosin PF05042.8 OAP57329.1 - 0.052 13.1 0.0 0.63 9.5 0.0 2.2 1 1 0 1 1 1 0 Caleosin related protein ORC2 PF04084.9 OAP57329.1 - 0.071 11.9 0.1 5.2 5.8 0.0 2.1 1 1 1 2 2 2 0 Origin recognition complex subunit 2 Rsc14 PF08586.5 OAP57329.1 - 0.075 13.5 0.4 10 6.6 0.1 2.2 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Toprim PF01751.17 OAP57329.1 - 0.085 12.8 0.1 2.7 8.0 0.0 2.3 1 1 0 1 1 1 0 Toprim domain Ribosomal_L11 PF00298.14 OAP57329.1 - 0.098 12.8 0.1 8.2 6.6 0.0 2.4 2 1 0 2 2 2 0 Ribosomal protein L11, RNA binding domain Toprim_4 PF13662.1 OAP57329.1 - 0.13 12.3 0.1 1.1 9.2 0.0 2.2 2 1 0 2 2 2 0 Toprim domain DUF533 PF04391.7 OAP57329.1 - 0.47 9.7 2.5 5 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DUF1296 PF06972.6 OAP57329.1 - 0.51 10.3 3.6 2.6 8.0 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1296) PB1 PF00564.19 OAP57329.1 - 0.52 10.0 3.0 24 4.6 0.0 3.5 2 1 1 3 3 3 0 PB1 domain DUF1691 PF07950.6 OAP57330.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) TPR_12 PF13424.1 OAP57332.1 - 1.6e-32 111.2 0.0 4.9e-08 32.7 0.0 6.1 5 1 1 6 6 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAP57332.1 - 2.3e-26 90.8 11.7 4.2e-07 29.6 0.1 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat NB-ARC PF00931.17 OAP57332.1 - 1.6e-08 33.7 0.0 8.6e-08 31.3 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 OAP57332.1 - 1.8e-07 31.1 0.3 5.2 7.9 0.0 7.9 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP57332.1 - 5.9e-07 29.7 0.0 0.36 11.1 0.0 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAP57332.1 - 7.1e-05 22.3 0.4 0.048 13.4 0.0 4.6 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAP57332.1 - 0.00052 20.0 0.1 0.19 12.0 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP57332.1 - 0.00066 19.3 2.3 0.3 11.1 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR PF01535.15 OAP57332.1 - 0.0008 19.2 0.1 0.074 13.0 0.0 3.9 4 0 0 4 4 3 1 PPR repeat AAA_22 PF13401.1 OAP57332.1 - 0.00099 19.2 0.0 0.012 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain TPR_20 PF14561.1 OAP57332.1 - 0.0015 18.5 0.0 0.79 9.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP57332.1 - 0.0074 16.9 1.8 1.6 9.4 0.0 4.6 5 1 1 6 6 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 OAP57332.1 - 0.0085 16.0 0.4 0.34 10.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Apc3 PF12895.2 OAP57332.1 - 0.012 15.7 0.0 0.56 10.3 0.0 2.9 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_17 PF13207.1 OAP57332.1 - 0.074 13.8 0.2 4 8.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 OAP57332.1 - 0.078 12.8 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 OAP57332.1 - 0.09 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase TPR_1 PF00515.23 OAP57332.1 - 0.16 11.6 1.8 27 4.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAP57332.1 - 0.16 11.7 1.9 29 4.7 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAP57332.1 - 0.55 10.8 12.0 4.6 7.9 0.0 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat p450 PF00067.17 OAP57333.1 - 1.8e-60 204.8 0.0 2.3e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HeLo PF14479.1 OAP57334.1 - 2.2e-54 184.4 1.9 3.3e-54 183.8 1.2 1.4 2 0 0 2 2 2 1 Prion-inhibition and propagation HET-s_218-289 PF11558.3 OAP57334.1 - 0.0026 17.7 0.9 0.0063 16.4 0.6 1.7 1 0 0 1 1 1 1 Het-s 218-289 F1F0-ATPsyn_F PF10791.4 OAP57335.1 - 2.8e-37 126.8 0.3 3.7e-37 126.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 OAP57335.1 - 0.0078 16.2 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f PAM2 PF07145.10 OAP57337.1 - 0.03 13.8 0.2 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region SH3_9 PF14604.1 OAP57338.1 - 4.7e-07 29.3 0.5 1.1e-06 28.1 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain Mid2 PF04478.7 OAP57338.1 - 0.0001 21.7 0.2 0.00019 20.8 0.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SH3_1 PF00018.23 OAP57338.1 - 0.00032 20.0 1.1 0.00041 19.6 0.1 1.7 2 0 0 2 2 2 1 SH3 domain Adeno_E3_CR2 PF02439.10 OAP57338.1 - 0.0015 18.0 2.0 0.0027 17.2 1.4 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF2668 PF10873.3 OAP57338.1 - 0.002 18.3 0.0 0.0053 16.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) EphA2_TM PF14575.1 OAP57338.1 - 0.0032 17.8 0.1 0.0067 16.7 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 OAP57338.1 - 0.0047 16.6 0.0 0.13 11.8 0.0 2.2 1 1 0 1 1 1 1 Rifin/stevor family Herpes_gE PF02480.11 OAP57338.1 - 0.0053 15.0 0.0 0.008 14.4 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 OAP57338.1 - 0.0092 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family IncA PF04156.9 OAP57338.1 - 0.11 12.1 1.1 0.19 11.2 0.8 1.4 1 0 0 1 1 1 0 IncA protein DUF1517 PF07466.6 OAP57338.1 - 0.13 11.1 0.6 0.38 9.7 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Arylesterase PF01731.15 OAP57339.1 - 0.046 13.6 3.8 44 4.1 0.0 4.4 3 2 1 4 4 4 0 Arylesterase UvdE PF03851.9 OAP57341.1 - 5.9e-108 360.0 0.0 7.7e-108 359.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE ADH_N PF08240.7 OAP57342.1 - 3.7e-27 94.2 4.7 6.3e-27 93.4 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP57342.1 - 3.3e-16 59.0 0.0 1e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP57342.1 - 0.0025 17.3 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 OAP57342.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAP57342.1 - 0.065 12.8 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP57342.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ABC_tran PF00005.22 OAP57344.1 - 6.6e-23 81.5 0.0 2.8e-11 43.8 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAP57344.1 - 2.1e-09 37.7 5.0 0.007 16.3 0.0 3.2 2 1 0 3 3 3 3 AAA domain SbcCD_C PF13558.1 OAP57344.1 - 4e-06 26.6 0.0 0.0062 16.4 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 OAP57344.1 - 0.00083 19.4 0.0 0.22 11.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 OAP57344.1 - 0.0089 15.5 0.2 0.017 14.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAP57344.1 - 0.013 15.4 0.4 0.28 11.1 0.0 2.8 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.1 OAP57344.1 - 0.087 13.1 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAP57344.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 OAP57344.1 - 0.26 10.7 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Metallophos PF00149.23 OAP57345.1 - 9.4e-38 129.6 0.0 9.5e-37 126.3 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Smg4_UPF3 PF03467.10 OAP57346.1 - 1.9e-21 76.8 1.0 4.9e-21 75.4 0.0 2.2 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 OAP57346.1 - 1.4e-08 34.2 0.5 2.3e-07 30.3 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP57346.1 - 3.5e-05 23.7 0.0 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP57346.1 - 9.5e-05 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAP57346.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Mre11_DNA_bind PF04152.9 OAP57347.1 - 6.7e-52 175.8 1.6 6.7e-52 175.8 1.1 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 OAP57347.1 - 1.6e-28 99.5 4.6 2.2e-28 99.0 3.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 OAP57347.1 - 0.0019 17.3 0.0 0.0083 15.3 0.0 1.9 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily PBP1_TM PF14812.1 OAP57347.1 - 0.95 9.8 24.2 0.44 10.8 5.4 4.6 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Grp1_Fun34_YaaH PF01184.14 OAP57349.1 - 8e-33 113.5 24.6 1e-32 113.1 17.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family F-box-like PF12937.2 OAP57351.1 - 6e-10 38.7 0.3 1.9e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAP57351.1 - 1.3e-09 37.4 0.1 2.5e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain NAD_binding_2 PF03446.10 OAP57352.1 - 1.7e-40 138.5 0.1 3.4e-40 137.5 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP57352.1 - 2.2e-27 95.5 0.0 3.5e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 OAP57352.1 - 5.9e-05 21.9 0.0 8.9e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 OAP57352.1 - 0.00019 21.8 0.0 0.00051 20.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 OAP57352.1 - 0.0058 15.7 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 OAP57352.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF970 PF06153.6 OAP57352.1 - 0.061 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF970) TrkA_N PF02254.13 OAP57352.1 - 0.084 12.8 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Fungal_trans_2 PF11951.3 OAP57353.1 - 8.8e-10 37.7 0.0 1.9e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mannosyl_trans3 PF11051.3 OAP57354.1 - 1e-73 248.0 0.0 2.3e-73 246.8 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative MAP65_ASE1 PF03999.7 OAP57355.1 - 1.3e-74 252.0 2.2 1.3e-74 252.0 1.5 2.5 2 1 1 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.7 OAP57355.1 - 0.011 15.5 0.5 0.049 13.4 0.3 2.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1140 PF06600.6 OAP57355.1 - 0.016 15.2 0.5 0.062 13.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) Spectrin PF00435.16 OAP57355.1 - 0.098 12.9 11.4 0.59 10.4 0.7 4.0 3 1 1 4 4 4 0 Spectrin repeat Sugar_tr PF00083.19 OAP57356.1 - 9.3e-88 294.7 19.3 1.1e-87 294.5 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57356.1 - 2e-24 85.9 29.6 1.3e-23 83.3 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 OAP57356.1 - 3.9e-05 22.5 1.1 0.00034 19.4 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TRI12 PF06609.8 OAP57356.1 - 8.2e-05 20.9 1.7 8.2e-05 20.9 1.2 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) F_bP_aldolase PF01116.15 OAP57357.1 - 3.8e-81 272.3 0.0 4.3e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 OAP57357.1 - 0.12 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family Epimerase PF01370.16 OAP57358.1 - 3.1e-16 59.5 0.0 4.6e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP57358.1 - 7.7e-11 41.2 0.0 1e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAP57358.1 - 8.2e-09 34.7 0.0 1.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 OAP57358.1 - 1.9e-06 26.9 0.1 2.1e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.18 OAP57358.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAP57358.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAP57358.1 - 0.0045 16.9 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.15 OAP57358.1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 OAP57358.1 - 0.076 12.6 0.0 1.2 8.7 0.0 2.5 3 0 0 3 3 3 0 KR domain Polysacc_synt_2 PF02719.10 OAP57358.1 - 0.14 11.0 0.0 0.28 10.0 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF348 PF03990.9 OAP57358.1 - 1.2 8.8 3.3 4.3 7.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF348) PhyH PF05721.8 OAP57359.1 - 2.5e-07 30.9 0.1 4.7e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 OAP57359.1 - 1.9e-06 26.6 0.5 0.041 12.3 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 OAP57360.1 - 6.9e-20 71.0 0.1 9.7e-20 70.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57360.1 - 6.9e-08 32.2 12.2 1.6e-07 31.1 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 OAP57361.1 - 7.5e-53 178.3 0.0 1.2e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP57361.1 - 1e-20 73.5 0.0 1.3e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP57361.1 - 0.00092 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sigma54_activ_2 PF14532.1 OAP57361.1 - 0.049 13.6 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain JAB PF01398.16 OAP57362.1 - 6.5e-29 99.9 0.0 1.3e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 OAP57362.1 - 4e-07 29.5 0.1 2.1e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 OAP57362.1 - 0.052 13.0 0.0 0.83 9.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) CENP-Q PF13094.1 OAP57363.1 - 0.077 13.0 3.0 0.18 11.8 0.8 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3763 PF12592.3 OAP57363.1 - 1.9 8.1 4.8 0.45 10.1 0.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3763) PX PF00787.19 OAP57364.1 - 8.1e-17 61.0 0.4 3e-16 59.2 0.1 2.1 2 0 0 2 2 2 1 PX domain Nucleoporin_FG PF13634.1 OAP57364.1 - 0.0005 20.2 0.5 0.0005 20.2 0.3 2.7 2 1 0 2 2 2 1 Nucleoporin FG repeat region Prefoldin_3 PF13758.1 OAP57364.1 - 1.2 8.9 3.8 0.58 9.9 0.1 2.4 3 0 0 3 3 3 0 Prefoldin subunit IBN_N PF03810.14 OAP57366.1 - 1.5e-07 31.2 0.0 1.1e-06 28.4 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 OAP57366.1 - 0.00023 21.0 1.3 0.35 10.7 0.0 5.3 7 1 0 7 7 7 1 Exportin 1-like protein Cse1 PF08506.5 OAP57366.1 - 0.0011 17.6 0.1 0.0026 16.4 0.1 1.6 1 0 0 1 1 1 1 Cse1 Cnd1 PF12717.2 OAP57366.1 - 0.11 12.3 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF2036 PF09724.4 OAP57367.1 - 3.6e-12 46.0 0.0 1.1e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) TraG_N PF07916.6 OAP57367.1 - 0.19 10.1 0.0 0.32 9.3 0.0 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Anp1 PF03452.9 OAP57368.1 - 1.1e-120 401.7 0.0 2.7e-120 400.5 0.0 1.5 2 0 0 2 2 2 1 Anp1 Glyco_tranf_2_4 PF13704.1 OAP57368.1 - 0.011 16.0 1.1 0.019 15.2 0.1 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 Rad54_N PF08658.5 OAP57368.1 - 0.053 13.2 0.8 0.11 12.2 0.6 1.5 1 0 0 1 1 1 0 Rad54 N terminal BTB PF00651.26 OAP57369.1 - 5.1e-05 23.2 0.0 8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Aa_trans PF01490.13 OAP57370.1 - 1.9e-22 79.3 35.9 3.3e-22 78.5 24.9 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein CBF PF03914.12 OAP57371.1 - 4.6e-44 149.7 0.4 4.6e-44 149.7 0.3 2.4 2 0 0 2 2 2 1 CBF/Mak21 family CinA PF02464.12 OAP57372.1 - 0.046 13.1 0.1 0.83 9.0 0.0 2.2 2 0 0 2 2 2 0 Competence-damaged protein Abhydrolase_6 PF12697.2 OAP57374.1 - 2.3e-22 79.9 6.6 3.7e-22 79.3 4.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP57374.1 - 4.3e-08 33.0 0.1 2e-07 30.8 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP57374.1 - 0.0089 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 OAP57374.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.3 OAP57374.1 - 0.047 13.5 0.7 0.29 11.0 0.2 2.4 3 0 0 3 3 3 0 Putative lysophospholipase PGA_cap PF09587.5 OAP57375.1 - 3.8e-45 154.1 0.0 1.2e-44 152.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap MFS_1 PF07690.11 OAP57376.1 - 1.4e-27 96.3 29.0 1.6e-27 96.1 18.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 OAP57377.1 - 3.3e-29 100.8 2.7 6.9e-29 99.8 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP57377.1 - 9.3e-23 80.1 0.0 1.8e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 OAP57377.1 - 0.048 13.5 0.1 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP57377.1 - 0.063 13.3 0.1 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1598 PF07643.6 OAP57377.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) AAA PF00004.24 OAP57378.1 - 9e-15 55.0 0.0 1.7e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAP57378.1 - 1.5e-09 38.1 0.4 8.4e-09 35.6 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAP57378.1 - 6.7e-08 32.7 0.0 1.8e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 OAP57378.1 - 4.5e-05 23.1 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.1 OAP57378.1 - 0.00039 20.1 0.1 0.0016 18.1 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 OAP57378.1 - 0.004 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP57378.1 - 0.0093 16.7 0.0 0.035 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 OAP57378.1 - 0.013 14.4 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 OAP57378.1 - 0.023 14.2 0.0 0.06 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 OAP57378.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_28 PF13521.1 OAP57378.1 - 0.032 14.2 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAP57378.1 - 0.076 12.6 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 OAP57378.1 - 0.085 12.5 0.3 0.69 9.6 0.0 2.4 2 0 0 2 2 2 0 NTPase KH_3 PF13014.1 OAP57379.1 - 0.00073 19.1 0.0 0.13 11.9 0.0 2.8 3 0 0 3 3 3 2 KH domain Prefoldin PF02996.12 OAP57380.1 - 2.6e-18 65.8 0.0 3.6e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Dynamitin PF04912.9 OAP57380.1 - 0.047 12.4 0.7 0.14 10.9 0.5 1.8 1 1 0 1 1 1 0 Dynamitin Snapin_Pallidin PF14712.1 OAP57380.1 - 0.088 13.1 1.1 1.5 9.2 0.4 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Fez1 PF06818.10 OAP57380.1 - 0.11 12.5 0.8 11 5.9 0.0 2.0 2 0 0 2 2 2 0 Fez1 Mst1_SARAH PF11629.3 OAP57380.1 - 0.16 11.8 0.3 0.41 10.4 0.1 1.7 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Med10 PF09748.4 OAP57380.1 - 0.18 11.5 0.4 18 5.1 0.1 2.5 2 1 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex tRNA-synt_2b PF00587.20 OAP57381.1 - 1.9e-30 105.7 0.1 3e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAP57381.1 - 1.8e-12 47.0 0.1 3.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Myb_Cef PF11831.3 OAP57383.1 - 2.9e-51 173.9 8.6 2.9e-51 173.9 6.0 4.1 3 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 OAP57383.1 - 1e-20 73.5 6.2 4.4e-14 52.3 1.3 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAP57383.1 - 1.8e-19 69.4 4.6 4e-09 36.3 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Lactonase PF10282.4 OAP57384.1 - 7.8e-60 202.7 0.0 1e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.7 OAP57384.1 - 0.012 15.2 0.0 0.35 10.5 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Sugar_tr PF00083.19 OAP57385.1 - 6.5e-75 252.4 23.9 7.8e-75 252.1 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57385.1 - 6.6e-22 77.7 20.6 6.6e-22 77.7 14.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Romo1 PF10247.4 OAP57385.1 - 2.7 8.2 7.9 3.4 7.9 0.1 3.9 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 DUF4387 PF14330.1 OAP57386.1 - 7.8e-34 115.9 0.0 1.4e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 OAP57386.1 - 1.5e-21 76.3 0.0 5e-20 71.2 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) GHL6 PF14871.1 OAP57386.1 - 0.12 12.3 0.0 1.7 8.6 0.0 2.6 1 1 2 3 3 3 0 Hypothetical glycosyl hydrolase 6 Fungal_trans PF04082.13 OAP57387.1 - 3.6e-10 39.1 0.3 7.6e-10 38.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57387.1 - 3.2e-06 26.9 6.6 5.8e-06 26.1 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP57388.1 - 4e-30 104.7 26.0 2.7e-25 88.8 7.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 OAP57388.1 - 6.8 6.7 7.8 64 3.6 3.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) GFA PF04828.9 OAP57389.1 - 7.2e-07 29.0 1.4 7.2e-07 29.0 1.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans PF04082.13 OAP57390.1 - 6.6e-08 31.7 0.3 1.8e-07 30.3 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57390.1 - 1.9e-05 24.4 8.8 3e-05 23.8 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_39 PF01229.12 OAP57391.1 - 2.7e-42 144.7 0.2 5.8e-42 143.6 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 GST_C PF00043.20 OAP57392.1 - 8.3e-09 35.3 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP57392.1 - 3.9e-08 33.3 0.0 9.4e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP57392.1 - 6.6e-07 29.1 0.1 1.3e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP57392.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP57392.1 - 1.6e-06 28.2 0.0 3.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAP57392.1 - 0.0099 16.3 0.1 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 OAP57393.1 - 2.2e-13 49.7 1.1 3.2e-13 49.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57393.1 - 4.1e-06 26.5 10.1 8.9e-06 25.5 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 OAP57394.1 - 7.8e-76 255.4 20.7 9.8e-76 255.1 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57394.1 - 1.6e-23 82.9 23.8 1.6e-23 82.9 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.11 OAP57395.1 - 7.6e-54 183.0 0.3 8.7e-54 182.8 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 OAP57395.1 - 0.058 13.9 0.4 2.2 8.8 0.3 2.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pyr_redox_3 PF13738.1 OAP57396.1 - 2.7e-19 70.0 0.0 2.5e-18 66.8 0.0 2.4 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP57396.1 - 3.8e-16 58.3 1.1 3.5e-09 35.4 0.0 3.3 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP57396.1 - 8.6e-12 44.9 0.0 2.9e-11 43.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP57396.1 - 1.2e-07 30.9 0.0 1.3e-05 24.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP57396.1 - 0.0005 19.8 0.1 0.0085 15.8 0.0 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAP57396.1 - 0.0072 15.4 0.0 0.039 13.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 OAP57396.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 OAP57396.1 - 0.23 9.8 0.1 0.37 9.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein adh_short_C2 PF13561.1 OAP57397.1 - 1e-31 110.5 0.0 1.2e-31 110.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57397.1 - 1.7e-27 96.3 0.7 2.8e-27 95.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57397.1 - 4.1e-16 59.1 0.1 7.5e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP57397.1 - 0.0018 17.7 0.0 0.0027 17.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 OAP57397.1 - 0.0049 16.8 0.1 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain AMP-binding PF00501.23 OAP57398.1 - 9.9e-83 277.8 0.0 1.3e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP57398.1 - 6.6e-13 49.4 0.0 1.8e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GST_N_3 PF13417.1 OAP57400.1 - 2e-14 53.5 0.0 3.2e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP57400.1 - 3.1e-13 49.6 0.0 5.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP57400.1 - 2.6e-10 40.1 0.0 3.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP57400.1 - 1.5e-09 37.6 0.0 2.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP57400.1 - 2.2e-07 30.6 0.1 4.1e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HET PF06985.6 OAP57401.1 - 7.8e-25 87.6 0.0 1.3e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.21 OAP57402.1 - 1.1e-10 41.1 1.3 1.9e-10 40.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP57402.1 - 1.2e-09 37.8 0.5 3.9e-09 36.2 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 OAP57402.1 - 0.0011 18.7 0.4 0.0026 17.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 OAP57402.1 - 0.078 12.9 0.8 0.13 12.2 0.5 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF2855 PF11017.3 OAP57402.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Abhydrolase_3 PF07859.8 OAP57404.1 - 1.7e-33 116.0 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAP57404.1 - 1.1e-12 47.3 0.0 1.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAP57404.1 - 1.1e-06 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 OAP57404.1 - 0.13 10.9 0.0 0.57 8.8 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family Lipase_3 PF01764.20 OAP57404.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 OAP57404.1 - 0.15 11.4 0.0 1.2 8.5 0.0 2.0 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase 4HBT PF03061.17 OAP57405.1 - 9.7e-10 38.4 0.3 1.7e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.1 OAP57405.1 - 0.00071 19.4 0.3 0.0017 18.1 0.1 1.6 1 1 1 2 2 2 1 Thioesterase-like superfamily DUF4442 PF14539.1 OAP57405.1 - 0.0039 17.1 0.1 0.0055 16.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) OPT PF03169.10 OAP57406.1 - 1.6e-150 502.5 42.6 1.9e-150 502.3 29.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.20 OAP57407.1 - 4.1e-18 65.8 0.0 7e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57407.1 - 5.7e-10 39.1 0.0 8.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP57407.1 - 1.4e-05 24.6 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NUMOD1 PF07453.8 OAP57407.1 - 0.1 12.4 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 NUMOD1 domain Polysacc_synt_2 PF02719.10 OAP57407.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 OAP57408.1 - 6.5e-17 61.9 0.1 9.5e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57408.1 - 7.2e-05 22.5 0.1 0.0001 22.0 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 OAP57408.1 - 0.085 11.7 0.1 0.2 10.5 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein NB-ARC PF00931.17 OAP57410.1 - 1.1e-06 27.7 0.0 2.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 OAP57410.1 - 2.8e-06 27.0 0.0 7.8e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 OAP57410.1 - 0.00013 22.1 0.0 0.00083 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP57410.1 - 0.00013 21.9 2.7 0.00054 19.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 OAP57410.1 - 0.019 15.1 0.0 0.059 13.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAP57410.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAP57410.1 - 0.14 11.9 0.1 20 4.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 OAP57410.1 - 0.8 10.5 5.6 0.57 11.0 0.1 3.0 1 1 1 2 2 2 0 AAA domain SNF2_N PF00176.18 OAP57411.1 - 1.1e-68 231.1 0.1 1.6e-68 230.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP57411.1 - 7.6e-14 51.3 0.0 2.7e-13 49.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP57411.1 - 7.3e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAP57411.1 - 0.00073 19.0 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Nop53 PF07767.6 OAP57412.1 - 2.3e-75 254.0 28.0 1.7e-74 251.1 19.4 1.9 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) TMEM247 PF15444.1 OAP57412.1 - 8 6.2 7.1 15 5.2 4.9 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 DUF221 PF02714.10 OAP57413.1 - 7.3e-103 343.8 27.8 2.7e-101 338.6 17.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAP57413.1 - 4.5e-45 153.0 1.6 4.5e-45 153.0 1.1 3.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 OAP57413.1 - 9.2e-30 102.3 0.0 2.8e-29 100.8 0.0 1.8 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 OAP57413.1 - 9.8e-18 64.4 1.7 1.7e-17 63.6 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RNase_P_Rpp14 PF01900.14 OAP57415.1 - 2.8e-29 101.1 0.0 4.2e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 OAP57416.1 - 2e-66 223.9 0.0 3e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 OAP57416.1 - 0.00025 21.8 1.0 0.0033 18.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 OAP57416.1 - 0.0012 17.6 0.3 0.0035 16.1 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 OAP57416.1 - 0.019 14.3 0.0 0.057 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 OAP57416.1 - 0.036 13.5 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 OAP57416.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 OAP57416.1 - 0.063 13.2 0.0 0.5 10.3 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 OAP57416.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAP57416.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 OAP57416.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MHYT PF03707.11 OAP57417.1 - 1.3e-10 41.1 10.9 2.8e-05 24.1 0.3 3.7 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat HTH_27 PF13463.1 OAP57417.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Peptidase_S10 PF00450.17 OAP57418.1 - 4e-112 375.4 0.0 5.5e-112 374.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAP57418.1 - 0.0015 18.4 0.0 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4328 PF14219.1 OAP57418.1 - 0.028 13.6 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) RRM_1 PF00076.17 OAP57420.1 - 1.9e-08 33.7 0.0 3.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP57420.1 - 1.4e-06 28.2 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_PH PF01138.16 OAP57421.1 - 1.3e-12 48.2 0.1 3.1e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Sulfotransfer_3 PF13469.1 OAP57421.1 - 0.0001 23.2 4.9 0.00042 21.2 3.3 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 OAP57421.1 - 0.053 12.7 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Spc97_Spc98 PF04130.8 OAP57422.1 - 2.3e-58 197.8 0.0 7.3e-58 196.2 0.0 1.8 1 1 1 2 2 2 1 Spc97 / Spc98 family UDPG_MGDP_dh_C PF03720.10 OAP57422.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ThiF PF00899.16 OAP57423.1 - 1.6e-57 193.1 0.1 1.4e-33 115.6 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 OAP57423.1 - 2.3e-38 131.1 0.0 5.9e-38 129.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 OAP57423.1 - 1.2e-37 127.2 0.7 8.7e-27 92.4 0.2 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 OAP57423.1 - 6.2e-26 89.5 1.2 9e-22 76.1 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 OAP57424.1 - 4e-23 81.1 0.2 3.5e-22 78.1 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP57424.1 - 9e-17 60.7 0.0 4.5e-16 58.4 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAP57424.1 - 3.6e-07 30.0 0.0 1.1e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP57424.1 - 2e-06 27.9 0.2 5.5e-05 23.3 0.1 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAP57424.1 - 0.00022 21.6 0.0 0.00045 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RdRP_1 PF00680.15 OAP57424.1 - 0.025 12.8 0.0 0.044 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA dependent RNA polymerase MFS_1 PF07690.11 OAP57427.1 - 8.2e-40 136.5 50.8 8.2e-40 136.5 35.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP57427.1 - 1.5e-14 53.1 25.1 2.3e-14 52.5 17.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4029 PF13221.1 OAP57427.1 - 0.01 16.1 1.3 0.066 13.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) DUF2919 PF11143.3 OAP57427.1 - 0.33 10.7 6.1 0.069 12.9 0.5 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2919) Zn_clus PF00172.13 OAP57428.1 - 0.0027 17.5 11.1 0.006 16.4 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3176 PF11374.3 OAP57429.1 - 9.2e-11 41.6 3.3 1.8e-10 40.6 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF2839 PF10999.3 OAP57429.1 - 0.34 10.9 3.2 8.5 6.4 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) OB_NTP_bind PF07717.11 OAP57430.1 - 7.4e-18 64.4 0.0 1.5e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAP57430.1 - 1.1e-16 60.6 0.0 2.8e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAP57430.1 - 4e-13 49.0 0.0 1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 OAP57430.1 - 1.2e-10 41.2 0.0 3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 OAP57430.1 - 4.4e-09 36.0 0.1 8.8e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.1 OAP57430.1 - 0.00031 20.1 0.0 0.00078 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAP57430.1 - 0.00032 20.1 0.0 0.00081 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain UBA PF00627.26 OAP57430.1 - 0.0007 19.3 0.8 0.12 12.2 0.0 3.8 4 0 0 4 4 4 1 UBA/TS-N domain Zot PF05707.7 OAP57430.1 - 0.0019 17.6 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.1 OAP57430.1 - 0.0023 17.6 0.1 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain KaiC PF06745.8 OAP57430.1 - 0.0024 17.0 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 OAP57430.1 - 0.0097 16.0 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 OAP57430.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAP57430.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family SMC_N PF02463.14 OAP57430.1 - 0.014 14.5 0.1 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Sigma54_activat PF00158.21 OAP57430.1 - 0.019 14.4 0.0 0.23 10.8 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_16 PF13191.1 OAP57430.1 - 0.029 14.3 0.1 0.18 11.7 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 OAP57430.1 - 0.032 13.1 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DND1_DSRM PF14709.1 OAP57430.1 - 0.038 14.2 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_11 PF13086.1 OAP57430.1 - 0.058 12.9 0.3 0.25 10.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 OAP57430.1 - 0.065 13.0 0.1 0.45 10.3 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Cyclin_N PF00134.18 OAP57431.1 - 1.2e-43 147.7 0.6 2.2e-43 146.8 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAP57431.1 - 7.4e-34 116.2 0.1 2.5e-33 114.4 0.1 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 OAP57432.1 - 0.0014 18.4 12.2 0.0026 17.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpc4 PF05132.9 OAP57433.1 - 2.2e-25 89.1 6.2 1.7e-23 83.0 0.0 3.9 3 1 0 3 3 3 2 RNA polymerase III RPC4 SepZ PF06066.6 OAP57434.1 - 0.43 10.5 3.3 0.22 11.5 0.2 2.0 2 1 1 3 3 3 0 SepZ CRCB PF02537.10 OAP57435.1 - 9.7e-35 118.9 12.3 1.2e-20 73.5 5.6 2.6 2 0 0 2 2 2 2 CrcB-like protein UPRTase PF14681.1 OAP57436.1 - 9.4e-73 243.8 0.0 1.1e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAP57436.1 - 2.2e-08 33.8 0.0 4.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UreD PF01774.12 OAP57437.1 - 3.3e-53 180.2 0.0 4.1e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 OAP57438.1 - 1.6e-29 101.9 0.4 1.6e-29 101.9 0.3 2.5 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.1 OAP57438.1 - 0.00012 22.3 2.6 0.0025 18.0 0.1 3.6 4 0 0 4 4 4 1 HEAT repeats DUF4446 PF14584.1 OAP57438.1 - 0.23 11.2 3.9 0.14 11.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TRAP_alpha PF03896.11 OAP57439.1 - 3e-09 36.2 0.0 4.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2893 PF11459.3 OAP57440.1 - 0.063 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) Herpes_capsid PF06112.6 OAP57440.1 - 9 6.3 9.1 31 4.5 6.3 1.9 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PhyH PF05721.8 OAP57443.1 - 2.3e-11 44.1 0.0 3.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.11 OAP57445.1 - 1.3e-27 96.4 22.7 1.8e-27 95.9 15.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP57445.1 - 3.7e-09 35.6 14.8 3.7e-09 35.6 10.2 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter Fungal_trans_2 PF11951.3 OAP57446.1 - 3.3e-18 65.4 7.4 5.5e-18 64.7 5.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57446.1 - 4.6e-05 23.2 12.6 8.6e-05 22.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 OAP57447.1 - 2.5e-89 300.1 0.0 3e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 Amidase AMP-binding PF00501.23 OAP57448.1 - 2.2e-84 283.2 0.0 2.9e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP57448.1 - 1.4e-12 48.3 0.9 1.4e-12 48.3 0.6 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Wyosine_form PF08608.7 OAP57449.1 - 6.4e-24 83.8 0.0 1.8e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 OAP57449.1 - 4.2e-22 79.0 0.1 9.4e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 OAP57449.1 - 8.1e-07 29.1 0.0 1.7e-05 24.8 0.0 2.6 1 1 0 1 1 1 1 Flavodoxin EF-hand_6 PF13405.1 OAP57450.1 - 0.017 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 OAP57450.1 - 0.029 13.6 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 EF hand EI24 PF07264.6 OAP57450.1 - 0.029 13.7 4.0 0.038 13.4 2.7 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) CytB6-F_Fe-S PF08802.5 OAP57450.1 - 0.096 12.6 2.2 0.096 12.6 1.6 2.4 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit MFS_1 PF07690.11 OAP57451.1 - 1.2e-31 109.6 32.0 1.2e-31 109.6 22.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Isochorismatase PF00857.15 OAP57452.1 - 5.9e-32 110.9 0.0 6.9e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PNP_UDP_1 PF01048.15 OAP57452.1 - 0.054 12.4 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphorylase superfamily PHD PF00628.24 OAP57453.1 - 8.6e-08 31.7 7.3 1.4e-07 31.0 5.0 1.3 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 OAP57453.1 - 0.0014 18.3 1.3 0.0027 17.3 0.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 OAP57453.1 - 0.012 14.9 1.1 0.026 13.8 0.8 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 OAP57453.1 - 0.015 14.6 1.4 0.029 13.6 1.0 1.5 1 0 0 1 1 1 0 PHD-finger SlyX PF04102.7 OAP57453.1 - 0.015 15.6 9.9 0.056 13.8 2.4 2.5 2 0 0 2 2 2 0 SlyX zf-HC5HC2H PF13771.1 OAP57453.1 - 0.017 15.2 4.1 0.038 14.1 2.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Rootletin PF15035.1 OAP57453.1 - 0.029 14.3 8.4 0.047 13.6 5.9 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 OAP57453.1 - 0.077 12.4 8.9 0.48 9.9 1.4 2.5 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.13 OAP57453.1 - 0.096 12.6 6.7 0.22 11.4 1.6 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family Prok-RING_1 PF14446.1 OAP57453.1 - 0.22 11.2 6.9 0.037 13.7 2.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Lzipper-MIP1 PF14389.1 OAP57453.1 - 0.35 11.0 6.2 0.73 9.9 2.6 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 APG6 PF04111.7 OAP57453.1 - 0.41 9.6 7.7 0.61 9.0 5.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4510 PF14971.1 OAP57453.1 - 0.44 10.6 9.5 0.06 13.5 3.5 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4510) Mod_r PF07200.8 OAP57453.1 - 0.54 10.1 8.6 0.18 11.7 3.2 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fib_alpha PF08702.5 OAP57453.1 - 0.58 10.2 7.5 3.6 7.7 0.8 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 OAP57453.1 - 0.82 10.0 10.7 0.22 11.8 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 OAP57453.1 - 1 8.9 12.9 0.89 9.1 6.0 2.0 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 OAP57453.1 - 2.4 8.5 9.1 1.1 9.6 2.8 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF972) FlxA PF14282.1 OAP57453.1 - 4.1 7.3 9.5 0.13 12.2 1.1 2.4 2 1 0 2 2 2 0 FlxA-like protein DUF4140 PF13600.1 OAP57453.1 - 6.6 7.2 11.7 10 6.6 0.8 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Aminotran_5 PF00266.14 OAP57454.1 - 1.7e-20 73.0 0.0 3e-20 72.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAP57454.1 - 0.023 13.0 0.0 0.14 10.4 0.0 1.9 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme tRNA_int_end_N2 PF12928.2 OAP57455.1 - 2.4e-22 78.1 0.0 5.1e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 OAP57455.1 - 0.0015 18.0 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Skp1_POZ PF03931.10 OAP57456.1 - 1.5e-12 47.4 0.0 1.9e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 OAP57456.1 - 0.0021 18.0 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain ThiF PF00899.16 OAP57457.1 - 6.4e-42 142.6 0.1 1.2e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 OAP57457.1 - 3.7e-30 103.2 0.1 7.5e-30 102.3 0.1 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 OAP57457.1 - 3.9e-19 67.7 2.1 3.9e-19 67.7 1.5 2.7 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 OAP57457.1 - 6.1e-19 67.9 1.3 3.3e-18 65.5 0.5 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 OAP57457.1 - 0.0012 19.0 0.0 0.0059 16.8 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 OAP57457.1 - 0.0035 17.4 0.0 0.0085 16.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 OAP57457.1 - 0.018 15.4 1.0 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF2419 PF10343.4 OAP57458.1 - 1.8e-123 411.4 0.0 2.1e-123 411.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) PEMT PF04191.8 OAP57459.1 - 5.2e-60 200.1 9.4 4.6e-37 126.3 0.5 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase ParA PF10609.4 OAP57460.1 - 4.2e-36 122.6 0.0 1.3e-35 121.1 0.0 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 OAP57460.1 - 6.6e-15 55.0 0.0 1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAP57460.1 - 1.1e-06 28.6 0.0 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 OAP57460.1 - 1.6e-05 24.1 0.4 0.00098 18.2 0.1 2.7 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 OAP57460.1 - 0.0022 17.1 0.0 0.0042 16.2 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 OAP57460.1 - 0.0032 17.1 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAP57460.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 OAP57460.1 - 0.089 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAP57460.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 OAP57460.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Fer4_NifH PF00142.13 OAP57460.1 - 0.14 11.2 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.1 OAP57460.1 - 0.15 12.9 0.1 0.22 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Asp PF00026.18 OAP57461.1 - 1.2e-61 208.7 5.2 1.4e-61 208.5 3.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 OAP57461.1 - 8.9e-06 26.1 6.5 0.03 14.8 1.1 3.6 3 1 0 3 3 3 2 Aspartyl protease CRT10 PF08728.5 OAP57461.1 - 0.1 10.5 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 CRT10 Thr_synth_N PF14821.1 OAP57463.1 - 2e-23 82.1 0.0 5e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 OAP57463.1 - 5.7e-22 78.3 0.0 4.7e-21 75.3 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF302 PF03625.9 OAP57464.1 - 2.2e-05 23.9 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF302 Ammonium_transp PF00909.16 OAP57466.1 - 6.2e-74 248.8 18.9 7.1e-74 248.6 13.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family AA_permease_2 PF13520.1 OAP57467.1 - 4.5e-43 147.3 49.0 6.3e-43 146.8 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP57467.1 - 1.4e-26 92.9 44.7 1.8e-26 92.5 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.8 OAP57468.1 - 5.8e-60 202.4 0.9 8.3e-60 201.9 0.6 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP57468.1 - 0.00028 19.7 0.5 0.0012 17.6 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAP57468.1 - 0.0004 20.1 0.2 0.00064 19.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3390 PF11870.3 OAP57468.1 - 0.056 13.3 0.3 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Chlorophyllase2 PF12740.2 OAP57468.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme adh_short_C2 PF13561.1 OAP57469.1 - 3e-32 112.3 0.0 3.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57469.1 - 3e-22 79.2 3.2 6.9e-22 78.1 2.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57469.1 - 2.6e-09 36.9 1.2 4.3e-09 36.2 0.8 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP57469.1 - 0.00085 19.0 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP57469.1 - 0.016 14.6 0.2 0.047 13.1 0.2 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 OAP57470.1 - 6e-28 96.9 1.7 1e-27 96.2 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP57470.1 - 4.5e-11 43.7 1.0 7e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP57470.1 - 1.9e-06 27.5 0.6 2.2e-05 24.1 0.0 2.8 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 OAP57470.1 - 0.0046 16.9 1.3 0.019 14.9 0.2 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2493 PF10686.4 OAP57470.1 - 0.28 10.7 2.1 6.4 6.3 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2493) ATP-synt_J PF04911.7 OAP57471.1 - 2.7e-22 77.9 1.5 2.9e-22 77.8 1.1 1.0 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.6 OAP57472.1 - 4.9e-49 165.8 2.8 6.3e-49 165.5 1.9 1.1 1 0 0 1 1 1 1 Spc19 Prefoldin_2 PF01920.15 OAP57472.1 - 0.015 15.0 6.0 3.4 7.4 0.0 2.6 3 0 0 3 3 3 0 Prefoldin subunit ADIP PF11559.3 OAP57472.1 - 0.32 10.8 9.7 0.74 9.6 2.1 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Tnp_P_element PF12017.3 OAP57472.1 - 0.41 9.8 3.0 1.1 8.4 0.9 2.0 2 0 0 2 2 2 0 Transposase protein TPR_MLP1_2 PF07926.7 OAP57472.1 - 0.66 9.7 7.2 1.2 8.8 0.1 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-CCCH PF00642.19 OAP57473.1 - 2e-05 24.1 1.4 2e-05 24.1 1.0 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4062 PF13271.1 OAP57473.1 - 0.13 12.3 0.2 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) Toxin_YhaV PF11663.3 OAP57473.1 - 0.17 11.6 1.2 0.35 10.6 0.2 2.1 2 1 0 2 2 2 0 Toxin with endonuclease activity YhaV Peptidase_M20 PF01546.23 OAP57474.1 - 4.6e-27 94.7 0.0 6.2e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAP57474.1 - 2.1e-15 56.4 0.0 3.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain NMT1_2 PF13379.1 OAP57474.1 - 0.0087 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 NMT1-like family PAX PF00292.13 OAP57474.1 - 0.026 14.2 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 'Paired box' domain FAD_binding_7 PF03441.9 OAP57475.1 - 8e-85 284.3 0.1 1.2e-84 283.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAP57475.1 - 9.1e-35 119.8 0.3 1.8e-34 118.8 0.2 1.5 1 0 0 1 1 1 1 DNA photolyase Glyco_hydro_3 PF00933.16 OAP57476.1 - 1.3e-94 316.6 0.0 1.8e-94 316.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAP57476.1 - 4.8e-57 193.1 0.4 1.5e-56 191.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 OAP57476.1 - 2.3e-16 59.4 0.1 4.7e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PIR PF00399.14 OAP57476.1 - 7e-09 34.7 32.1 0.00019 20.6 3.4 4.3 3 1 1 4 4 4 3 Yeast PIR protein repeat EBP PF05241.7 OAP57477.1 - 7.8e-08 31.5 3.0 1.2e-07 30.9 0.8 1.9 2 0 0 2 2 2 1 Emopamil binding protein ECH PF00378.15 OAP57478.1 - 9.6e-31 106.7 0.0 1.2e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Med31 PF05669.7 OAP57479.1 - 7.5e-29 99.4 0.6 9.8e-29 99.1 0.4 1.1 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.6 OAP57480.1 - 2.4e-49 167.4 0.0 6.1e-49 166.0 0.0 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein FtsX PF02687.16 OAP57481.1 - 0.035 13.8 0.7 0.15 11.8 0.5 2.0 1 0 0 1 1 1 0 FtsX-like permease family Arch_ATPase PF01637.13 OAP57483.1 - 0.0001 22.0 0.1 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase ATP-synt_ab PF00006.20 OAP57483.1 - 0.0017 17.8 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 OAP57483.1 - 0.0026 17.7 0.8 0.039 13.9 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 OAP57483.1 - 0.012 16.0 0.0 0.058 13.8 0.0 2.2 1 1 1 2 2 2 0 Miro-like protein DUF815 PF05673.8 OAP57483.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 OAP57483.1 - 0.094 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLU PF13236.1 OAP57484.1 - 8.2e-81 270.6 0.0 1.3e-80 269.9 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 OAP57484.1 - 1.1e-49 168.6 0.0 3e-49 167.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 OAP57484.1 - 9.4e-28 96.1 0.9 3.4e-27 94.4 0.6 2.1 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 OAP57484.1 - 1.3e-22 79.5 3.9 7.4e-12 45.0 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAP57484.1 - 9e-21 73.1 0.1 6.8e-07 29.0 0.0 4.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAP57484.1 - 7.4e-07 28.7 0.2 0.078 12.6 0.0 3.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 OAP57484.1 - 1e-05 25.0 1.8 6.1 7.0 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP57484.1 - 0.0018 17.8 1.3 2.7 7.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAP57484.1 - 0.0043 17.6 0.4 10 6.9 0.0 4.0 1 1 1 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.7 OAP57484.1 - 0.0044 16.8 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF727) WD40 PF00400.27 OAP57487.1 - 4.2e-42 140.5 4.6 2.1e-08 33.7 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 OAP57487.1 - 7.4e-09 35.1 0.6 1.6e-08 34.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP57487.1 - 1.6e-07 30.7 0.3 3.1e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 OAP57487.1 - 1.5e-05 23.4 0.2 0.0016 16.6 0.0 3.2 3 1 1 4 4 4 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 OAP57487.1 - 0.0034 17.1 0.1 6.5 6.5 0.0 3.7 3 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Peptidase_U57 PF05582.7 OAP57487.1 - 0.086 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 YabG peptidase U57 Fork_head PF00250.13 OAP57488.1 - 1.5e-36 124.2 0.7 3.1e-36 123.3 0.5 1.4 1 0 0 1 1 1 1 Fork head domain Arb2 PF09757.4 OAP57488.1 - 6.2e-13 48.5 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain FHA PF00498.21 OAP57488.1 - 9.8e-09 35.2 0.0 2.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF3245 PF11595.3 OAP57488.1 - 0.36 11.0 4.0 0.24 11.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) RRM_6 PF14259.1 OAP57490.1 - 9.8e-14 51.0 0.0 9.3e-09 35.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP57490.1 - 3.1e-13 49.1 0.0 3.1e-06 26.7 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 OAP57490.1 - 8.1e-10 38.3 0.8 1.6e-09 37.3 0.6 1.5 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.13 OAP57490.1 - 3.4e-09 35.6 1.4 6.1e-09 34.8 1.0 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 OAP57490.1 - 6.2e-07 29.1 0.2 2e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_5 PF13893.1 OAP57490.1 - 0.0051 16.6 0.5 4.5 7.1 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin-related PF06548.6 OAP57490.1 - 0.032 12.8 2.8 0.051 12.1 1.9 1.2 1 0 0 1 1 1 0 Kinesin-related DHC_N1 PF08385.7 OAP57490.1 - 0.2 9.9 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Yae1_N PF09811.4 OAP57491.1 - 3.8e-10 39.1 0.5 5.9e-10 38.5 0.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Sigma70_ner PF04546.8 OAP57491.1 - 0.41 10.2 6.3 0.51 9.9 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Acatn PF13000.2 OAP57492.1 - 7.7e-140 466.9 23.6 1.1e-74 251.8 6.8 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 EBV-NA3 PF05009.7 OAP57492.1 - 0.76 8.9 2.9 1.3 8.1 2.0 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CENP-O PF09496.5 OAP57493.1 - 2.3e-21 75.8 0.0 3.9e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Cyclase PF04199.8 OAP57494.1 - 1e-12 48.0 0.3 4.5e-12 45.9 0.2 1.8 1 1 0 1 1 1 1 Putative cyclase STAT1_TAZ2bind PF12162.3 OAP57494.1 - 0.077 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain adh_short_C2 PF13561.1 OAP57495.1 - 9.1e-30 104.1 0.0 1.1e-29 103.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57495.1 - 1e-25 90.6 2.5 1e-25 90.6 1.8 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP57495.1 - 8.1e-09 35.3 1.2 1.3e-08 34.7 0.9 1.4 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 OAP57495.1 - 0.024 14.4 0.1 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAP57495.1 - 0.14 11.7 0.3 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 OAP57495.1 - 0.15 11.8 1.0 0.48 10.2 0.7 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sugar_tr PF00083.19 OAP57496.1 - 1.5e-84 284.2 18.2 1.7e-84 284.0 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57496.1 - 5.1e-26 91.2 28.6 2e-21 76.0 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP57497.1 - 5.5e-41 140.4 23.0 7.1e-41 140.0 16.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP57497.1 - 2.7e-16 59.2 47.5 7.6e-16 57.7 31.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.1 OAP57498.1 - 7.6e-30 104.4 0.0 9.4e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57498.1 - 9.7e-27 93.9 0.0 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57498.1 - 5.2e-16 58.8 0.0 8.4e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 OAP57498.1 - 0.026 13.2 0.1 0.035 12.8 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.13 OAP57499.1 - 1.8e-25 89.3 1.0 2.9e-25 88.6 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57499.1 - 8.5e-06 25.5 12.8 8.5e-06 25.5 8.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2201_N PF13203.1 OAP57500.1 - 4.2 6.4 18.3 2.6 7.1 0.6 2.4 2 0 0 2 2 2 0 Putative metallopeptidase domain Ureidogly_hydro PF04115.7 OAP57501.1 - 5.7e-12 45.2 0.0 4.6e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Ureidoglycolate hydrolase APG6 PF04111.7 OAP57502.1 - 0.033 13.2 4.3 0.039 13.0 3.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4456 PF14644.1 OAP57502.1 - 0.041 13.0 6.5 0.057 12.6 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Activator-TraM PF11657.3 OAP57502.1 - 0.06 12.8 6.5 0.057 12.8 2.8 1.8 2 0 0 2 2 2 0 Transcriptional activator TraM V_ATPase_I PF01496.14 OAP57502.1 - 2.2 6.0 5.4 2.9 5.6 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCM2_N PF12619.3 OAP57502.1 - 3.2 7.7 9.5 5.1 7.0 6.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 MAPEG PF01124.13 OAP57503.1 - 3.3e-12 46.1 3.7 4.2e-12 45.7 2.6 1.2 1 0 0 1 1 1 1 MAPEG family V-ATPase_H_N PF03224.9 OAP57503.1 - 0.18 10.8 0.1 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H DFP PF04127.10 OAP57505.1 - 3.9e-18 65.7 0.0 1.1e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RTA1 PF04479.8 OAP57506.1 - 4.3e-15 55.8 5.5 6.1e-15 55.3 3.8 1.1 1 0 0 1 1 1 1 RTA1 like protein NB PF04159.8 OAP57506.1 - 0.15 11.8 0.8 0.28 10.9 0.6 1.4 1 0 0 1 1 1 0 NB glycoprotein AAA_10 PF12846.2 OAP57508.1 - 4.2e-09 36.2 0.0 1.3e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 OAP57508.1 - 0.0033 17.5 0.0 4.2 7.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zot PF05707.7 OAP57508.1 - 0.014 14.8 0.2 0.043 13.2 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Cu-oxidase_3 PF07732.10 OAP57509.1 - 3.3e-39 133.2 0.8 6.6e-36 122.6 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP57509.1 - 5.1e-31 107.0 3.5 6.4e-23 80.7 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 OAP57509.1 - 3.6e-18 65.9 0.0 4.8e-17 62.3 0.0 2.6 2 1 0 2 2 2 1 Multicopper oxidase GFO_IDH_MocA PF01408.17 OAP57510.1 - 1e-08 35.7 0.7 2.4e-08 34.5 0.5 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pterin_bind PF00809.17 OAP57510.1 - 0.08 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Pterin binding enzyme PPV_E2_C PF00511.12 OAP57511.1 - 0.057 13.3 0.1 0.76 9.7 0.0 2.4 2 0 0 2 2 2 0 E2 (early) protein, C terminal E1-E2_ATPase PF00122.15 OAP57512.1 - 1.7e-59 200.6 0.5 1.7e-59 200.6 0.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAP57512.1 - 3.5e-46 157.0 9.5 3.5e-46 157.0 6.6 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAP57512.1 - 1.1e-25 91.3 0.1 4.5e-25 89.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP57512.1 - 7.3e-17 61.1 0.0 1.5e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAP57512.1 - 1.8e-13 51.0 0.1 6.8e-13 49.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAP57512.1 - 1e-10 40.9 0.0 3.7e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAP57512.1 - 0.0003 20.4 0.4 0.0029 17.2 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF21 PF01595.15 OAP57512.1 - 0.033 13.4 0.3 0.033 13.4 0.2 4.0 4 1 0 4 4 4 0 Domain of unknown function DUF21 MFS_1 PF07690.11 OAP57513.1 - 6.9e-47 159.8 20.7 6.9e-47 159.8 14.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP57513.1 - 1.3e-12 47.0 6.6 1.3e-12 47.0 4.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAP57513.1 - 0.0012 17.1 1.5 0.0012 17.1 1.0 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MoaE PF02391.12 OAP57514.1 - 1.1e-28 99.4 0.0 1.3e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 MoaE protein DUF4632 PF15451.1 OAP57514.1 - 0.061 13.2 0.5 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) SCO1-SenC PF02630.9 OAP57515.1 - 8.4e-58 194.8 0.0 1.2e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 OAP57515.1 - 2e-05 24.2 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 OAP57515.1 - 0.00088 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Amidohydro_1 PF01979.15 OAP57516.1 - 4.3e-14 52.9 4.6 6.4e-14 52.3 3.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 OAP57516.1 - 2.6e-09 36.7 0.1 1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP57516.1 - 3.3e-05 23.3 1.0 0.0093 15.2 0.2 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 OAP57516.1 - 4.7e-05 23.5 5.3 0.0038 17.3 3.7 2.7 1 1 0 1 1 1 1 Amidohydrolase Cyt-b5 PF00173.23 OAP57517.1 - 1.3e-13 50.5 0.0 1.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Grp1_Fun34_YaaH PF01184.14 OAP57518.1 - 5.2e-62 208.8 12.9 6.3e-62 208.6 8.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3671 PF12420.3 OAP57518.1 - 0.046 13.7 0.5 0.091 12.7 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function FAA_hydrolase PF01557.13 OAP57519.1 - 2.2e-58 197.2 0.1 3.2e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 OAP57519.1 - 4.1e-32 111.8 0.3 6.5e-32 111.2 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP57519.1 - 3.3e-17 62.5 1.1 9.1e-16 57.9 0.8 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP57519.1 - 6.5e-16 58.5 0.3 3.4e-10 39.8 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 OAP57519.1 - 6.7e-05 22.5 0.3 0.00015 21.3 0.1 1.6 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 OAP57519.1 - 0.00068 19.2 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 OAP57519.1 - 0.0044 16.4 0.1 0.0074 15.7 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.5 OAP57519.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Hydrolase_4 PF12146.3 OAP57519.1 - 0.12 12.2 0.2 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Fungal_trans PF04082.13 OAP57520.1 - 3e-15 55.8 0.6 5.4e-15 54.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57520.1 - 5.9e-08 32.4 8.3 1.3e-07 31.3 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPE65 PF03055.10 OAP57521.1 - 2.1e-133 445.4 0.0 2.4e-133 445.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.6 OAP57521.1 - 0.0043 16.6 0.1 0.013 15.0 0.1 1.7 1 0 0 1 1 1 1 Protein phosphatase inhibitor SQS_PSY PF00494.14 OAP57522.1 - 2.6e-59 200.7 0.3 4.3e-59 199.9 0.2 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.19 OAP57522.1 - 1.1e-16 61.0 0.2 3.4e-16 59.3 0.2 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP57522.1 - 4.4e-14 52.2 0.1 1e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP57522.1 - 6.5e-09 35.1 1.7 3.8e-08 32.6 1.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP57522.1 - 0.00022 20.2 2.6 0.0004 19.3 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 OAP57522.1 - 0.00044 19.4 0.0 0.003 16.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP57522.1 - 0.00058 18.4 0.1 0.0084 14.6 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAP57522.1 - 0.00059 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP57522.1 - 0.00085 19.4 0.0 0.012 15.6 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP57522.1 - 0.038 13.0 0.1 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 OAP57522.1 - 0.21 10.5 0.3 0.38 9.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 OAP57522.1 - 0.33 9.7 1.1 0.57 8.9 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Bac_rhodopsin PF01036.13 OAP57523.1 - 1.7e-45 155.0 21.3 2.1e-45 154.7 14.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein YwiC PF14256.1 OAP57523.1 - 5.7 7.0 15.1 6.5 6.8 7.5 2.6 1 1 1 2 2 2 0 YwiC-like protein Fungal_trans PF04082.13 OAP57525.1 - 1.4e-05 24.0 0.6 2.6e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57525.1 - 0.0012 18.7 2.3 0.0012 18.7 1.6 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.6 OAP57526.1 - 8.6e-09 34.7 0.0 2.8e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 OAP57526.1 - 0.047 13.0 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 OAP57526.1 - 0.09 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Cupin Transp_cyt_pur PF02133.10 OAP57527.1 - 4.6e-78 262.7 41.7 5.3e-78 262.5 28.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_5 PF12695.2 OAP57528.1 - 3.2e-10 39.9 0.0 1.3e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP57528.1 - 1.1e-08 35.2 1.5 1.1e-08 35.2 0.3 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP57528.1 - 0.016 14.4 0.0 0.042 13.0 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family AMP-binding PF00501.23 OAP57529.1 - 2.9e-46 157.7 0.0 4.3e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP57529.1 - 0.00058 20.7 0.0 0.0013 19.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_4 PF12799.2 OAP57530.1 - 2.6e-13 49.2 14.8 2.8e-09 36.4 4.4 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAP57530.1 - 6.1e-09 35.5 4.1 1.3e-08 34.4 2.0 2.3 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 OAP57530.1 - 1.3e-06 27.6 10.8 0.0036 17.1 0.2 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 OAP57530.1 - 6.7e-05 22.4 9.5 0.088 13.0 0.4 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 OAP57530.1 - 0.0027 17.5 5.8 1.9 8.8 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich repeat TctC PF03401.9 OAP57530.1 - 0.19 10.6 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor DUF2361 PF10153.4 OAP57532.1 - 3.4e-29 101.3 3.9 3.4e-29 101.3 2.7 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) WD40 PF00400.27 OAP57533.1 - 0.016 15.0 1.6 21 5.1 0.3 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat VIT1 PF01988.14 OAP57534.1 - 0.68 9.3 5.2 0.44 10.0 0.7 2.5 1 1 0 2 2 2 0 VIT family Peptidase_A4 PF01828.12 OAP57535.1 - 2.1e-40 138.0 12.2 2.7e-40 137.6 8.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_S3 PF00944.14 OAP57535.1 - 0.1 11.9 0.2 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Alphavirus core protein Ank_2 PF12796.2 OAP57536.1 - 2.8e-18 66.0 0.0 1.7e-10 41.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAP57536.1 - 1.1e-17 62.9 0.3 8.5e-07 28.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAP57536.1 - 1e-15 57.3 0.0 5e-09 36.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP57536.1 - 4.4e-15 55.7 0.1 6.5e-10 39.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP57536.1 - 1.9e-10 39.9 0.0 0.0014 18.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Astacin PF01400.19 OAP57536.1 - 1.6e-06 27.6 0.1 2.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 OAP57536.1 - 1.3e-05 24.9 1.1 3.6e-05 23.5 0.8 1.7 1 1 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.1 OAP57536.1 - 0.0068 16.3 0.4 0.0091 15.9 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 OAP57536.1 - 0.026 15.0 1.1 0.072 13.6 0.0 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 OAP57536.1 - 0.036 13.7 0.3 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.1 OAP57536.1 - 0.085 12.3 0.2 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF955 PF06114.8 OAP57536.1 - 0.15 11.8 0.2 0.35 10.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF955) p450 PF00067.17 OAP57537.1 - 7.4e-52 176.4 0.0 9e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAP57538.1 - 5e-16 58.2 0.0 6.3e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase PF00903.20 OAP57539.1 - 4.5e-14 52.5 0.0 6.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP57539.1 - 1e-09 38.9 0.0 1.4e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 OAP57539.1 - 0.028 14.4 0.0 0.078 12.9 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1220 PF06758.8 OAP57539.1 - 0.13 12.0 0.0 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Repeat of unknown function (DUF1220) FAD_binding_3 PF01494.14 OAP57540.1 - 4.3e-80 269.4 0.0 5.4e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP57540.1 - 0.00093 19.3 0.1 0.012 15.6 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP57540.1 - 0.0066 15.3 0.1 0.73 8.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Polysacc_deac_1 PF01522.16 OAP57540.1 - 0.016 14.8 0.0 5.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide deacetylase Pyr_redox_2 PF07992.9 OAP57540.1 - 0.019 14.8 0.0 0.1 12.4 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP57540.1 - 0.03 14.7 0.1 0.4 11.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CsgF PF10614.4 OAP57540.1 - 0.04 13.9 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein NAD_binding_8 PF13450.1 OAP57540.1 - 0.077 13.0 0.2 0.29 11.2 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.17 OAP57541.1 - 4.3e-83 279.3 0.0 8.2e-54 182.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SnoaL_4 PF13577.1 OAP57542.1 - 1.5e-05 24.9 0.1 2.3e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 OAP57542.1 - 0.00088 19.4 0.1 0.0014 18.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 OAP57542.1 - 0.038 14.3 0.1 0.055 13.8 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain Fungal_trans PF04082.13 OAP57543.1 - 3.7e-18 65.3 0.1 6.2e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain B2 PF11473.3 OAP57543.1 - 0.0024 17.3 0.0 0.0057 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding protein B2 Gas_vesicle_C PF01304.12 OAP57543.1 - 0.12 12.0 1.1 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain DUF1183 PF06682.7 OAP57544.1 - 1.5e-88 297.4 0.1 1.8e-88 297.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Tyr-DNA_phospho PF06087.7 OAP57545.1 - 1.7e-72 244.4 0.0 2.7e-72 243.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 OAP57545.1 - 0.0015 18.2 0.0 0.0096 15.6 0.0 2.1 2 0 0 2 2 2 1 PLD-like domain Phyto_Pns9_10 PF05878.6 OAP57545.1 - 1.7 7.6 2.9 3.9 6.3 2.0 1.6 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Gti1_Pac2 PF09729.4 OAP57546.1 - 1.2e-62 210.6 0.0 2e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family MBOAT PF03062.14 OAP57547.1 - 7.3e-53 179.7 4.8 1.4e-52 178.8 3.3 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.16 OAP57547.1 - 0.034 13.8 4.2 0.099 12.3 2.9 1.8 1 0 0 1 1 1 0 PAP2 superfamily Sec1 PF00995.18 OAP57548.1 - 2e-148 495.5 0.0 2.3e-148 495.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CDP-OH_P_transf PF01066.16 OAP57549.1 - 9.3e-17 61.1 6.1 1.8e-16 60.2 4.2 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.17 OAP57550.1 - 8.1e-158 525.3 0.0 1e-157 525.0 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 OAP57550.1 - 1.8e-13 50.3 0.0 1.3e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 OAP57550.1 - 2.9e-09 37.0 0.4 7e-09 35.8 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP57550.1 - 3.2e-07 29.7 0.2 5.3e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 OAP57550.1 - 1.6e-05 24.0 1.1 0.017 14.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP57550.1 - 0.00015 20.7 1.6 0.00015 20.7 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 OAP57550.1 - 0.0076 14.7 1.3 0.085 11.3 0.3 2.3 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 OAP57550.1 - 0.011 15.2 0.3 0.025 14.1 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 OAP57550.1 - 0.057 13.1 0.3 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 OAP57550.1 - 0.14 10.7 0.5 3.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Ank_2 PF12796.2 OAP57551.1 - 1.3e-28 99.1 1.8 9.6e-13 48.2 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP57551.1 - 1.1e-23 82.7 10.1 4.8e-08 32.9 0.1 8.5 4 3 5 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.25 OAP57551.1 - 6.9e-19 66.6 16.3 8.9e-05 22.1 0.0 10.0 11 1 0 11 11 11 5 Ankyrin repeat Ank_4 PF13637.1 OAP57551.1 - 2e-17 63.1 6.1 1.1e-07 32.1 0.0 6.7 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP57551.1 - 1.6e-14 52.5 8.8 0.13 12.5 0.0 9.2 9 0 0 9 9 9 4 Ankyrin repeat NACHT PF05729.7 OAP57551.1 - 2e-07 30.8 0.0 5.6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 OAP57551.1 - 0.079 12.7 0.0 0.33 10.7 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 OAP57551.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Torsin PF06309.6 OAP57551.1 - 0.12 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA PF00004.24 OAP57551.1 - 0.17 12.0 0.0 0.59 10.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Anticodon_1 PF08264.8 OAP57553.1 - 8e-13 48.4 0.0 1.7e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.17 OAP57553.1 - 1.1e-05 23.6 0.0 2.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAP57553.1 - 0.001 17.8 0.0 0.0021 16.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 OAP57554.1 - 6.8e-41 139.5 0.0 1.1e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.17 OAP57554.1 - 5.6e-31 107.2 0.0 8.5e-28 96.7 0.0 4.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAP57554.1 - 9.5e-24 83.7 0.0 3.7e-22 78.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) DUF247 PF03140.10 OAP57555.1 - 0.07 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function DUF3425 PF11905.3 OAP57556.1 - 5e-33 113.8 5.3 1.2e-32 112.5 3.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP57556.1 - 0.0083 16.0 9.6 0.0083 16.0 6.7 2.9 3 1 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 OAP57556.1 - 0.71 9.7 10.2 0.054 13.3 2.8 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Coatomer_E PF04733.9 OAP57557.1 - 6.2e-53 179.8 9.9 7e-53 179.6 6.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.1 OAP57557.1 - 1.8e-05 24.6 2.6 0.18 11.7 0.2 3.2 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP57557.1 - 6.4e-05 23.2 16.2 0.0054 17.0 1.9 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP57557.1 - 0.0014 18.4 2.7 0.42 10.6 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAP57557.1 - 0.0044 17.3 1.0 0.13 12.8 0.4 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAP57557.1 - 0.0071 17.0 14.2 0.072 13.7 0.5 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAP57557.1 - 0.028 14.0 0.0 7 6.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP57557.1 - 0.057 14.0 16.0 0.72 10.6 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Type_III_YscG PF09477.5 OAP57557.1 - 0.13 12.3 7.9 0.62 10.1 2.5 2.6 1 1 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_10 PF13374.1 OAP57557.1 - 1.9 8.5 7.1 12 6.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 OAP57558.1 - 1.3e-72 243.9 0.0 1.5e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 OAP57560.1 - 6.9e-76 255.6 26.1 8.1e-76 255.4 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57560.1 - 8.6e-22 77.3 46.8 4.2e-12 45.4 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.1 OAP57561.1 - 3.6e-28 98.9 1.2 4.3e-28 98.7 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57561.1 - 3.3e-22 79.1 2.1 6.4e-22 78.2 1.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57561.1 - 3.9e-05 23.3 0.9 6.5e-05 22.6 0.6 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 OAP57561.1 - 0.014 15.4 0.1 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TRI5 PF06330.6 OAP57562.1 - 6.4e-16 57.9 0.0 8.6e-16 57.5 0.0 1.3 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) Trp_syntA PF00290.15 OAP57563.1 - 1.2e-90 302.6 0.0 2e-90 301.8 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 OAP57563.1 - 1.1e-46 159.4 0.6 1.9e-46 158.6 0.4 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HET PF06985.6 OAP57565.1 - 1.7e-12 47.7 0.0 4.7e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4131 PF13567.1 OAP57566.1 - 0.086 12.2 1.0 3.7 6.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1989 PF09347.5 OAP57567.1 - 1.2e-51 174.4 0.0 1.7e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Aminotran_3 PF00202.16 OAP57568.1 - 2.3e-96 322.5 0.0 2.9e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SnoaL_2 PF12680.2 OAP57569.1 - 0.036 14.4 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain DUF1674 PF07896.7 OAP57570.1 - 6.9e-16 58.1 2.5 1.4e-15 57.2 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) PepSY_2 PF13670.1 OAP57570.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Inhibitor_I9 PF05922.11 OAP57571.1 - 9.6e-06 26.0 0.2 1.2e-05 25.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glyoxalase_2 PF12681.2 OAP57572.1 - 4.7e-17 62.5 0.0 8e-17 61.8 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP57572.1 - 3.1e-15 56.2 0.0 4.5e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 OAP57572.1 - 1.1e-10 41.4 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ubie_methyltran PF01209.13 OAP57573.1 - 1.3e-13 50.6 0.0 2.6e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 OAP57573.1 - 4.5e-12 46.3 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP57573.1 - 4.2e-10 39.8 0.0 1.2e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP57573.1 - 8.4e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP57573.1 - 3.7e-06 27.3 0.0 6.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP57573.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP57573.1 - 0.0074 16.8 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP57573.1 - 0.03 14.3 0.1 0.094 12.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 OAP57574.1 - 9.7e-58 195.7 0.0 1.3e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SET PF00856.23 OAP57575.1 - 8.4e-11 42.4 0.6 2.3e-09 37.7 0.4 2.3 1 1 0 1 1 1 1 SET domain Neur_chan_memb PF02932.11 OAP57576.1 - 0.088 12.6 0.9 0.11 12.3 0.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 OAP57576.1 - 0.1 11.5 1.8 0.14 11.1 1.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Phytase-like PF13449.1 OAP57577.1 - 2e-26 93.0 0.0 5.7e-26 91.5 0.0 1.7 2 1 0 2 2 2 1 Esterase-like activity of phytase LVIVD PF08309.6 OAP57577.1 - 0.047 12.6 1.1 0.84 8.6 0.0 3.0 3 0 0 3 3 3 0 LVIVD repeat DUF2823 PF11034.3 OAP57578.1 - 5.9e-33 112.8 12.7 6.6e-33 112.6 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DKNYY PF13644.1 OAP57578.1 - 0.071 13.3 0.3 0.076 13.2 0.2 1.3 1 1 0 1 1 1 0 DKNYY family DUF3570 PF12094.3 OAP57578.1 - 0.2 10.3 2.0 0.22 10.2 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) DUF2207 PF09972.4 OAP57579.1 - 0.028 13.0 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PalH PF08733.5 OAP57579.1 - 0.094 11.5 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 PalH/RIM21 Serinc PF03348.10 OAP57579.1 - 0.41 9.3 2.4 0.64 8.6 1.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) WD40 PF00400.27 OAP57581.1 - 1.1e-56 186.7 8.3 1.3e-09 37.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 OAP57581.1 - 4.3e-06 26.5 0.0 0.15 11.7 0.0 3.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 OAP57581.1 - 0.00049 18.9 1.7 0.45 9.1 0.1 2.4 1 1 0 2 2 2 2 Nup133 N terminal like TRAPP PF04051.11 OAP57582.1 - 3e-16 59.3 0.0 8e-16 57.9 0.0 1.6 1 1 1 2 2 2 1 Transport protein particle (TRAPP) component HMGL-like PF00682.14 OAP57585.1 - 6.7e-63 212.5 0.0 1e-62 211.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 OAP57585.1 - 4.5e-23 81.5 0.6 2.9e-22 78.9 0.4 2.1 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain DAO PF01266.19 OAP57586.1 - 1.9e-50 171.7 0.0 2.6e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP57586.1 - 4.5e-09 35.6 1.0 2.5e-08 33.1 0.7 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAP57586.1 - 6.8e-08 31.9 0.1 2.8e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP57586.1 - 0.00052 19.1 0.8 0.33 10.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 OAP57586.1 - 0.00067 19.5 0.1 0.0018 18.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 OAP57586.1 - 0.0015 18.2 0.2 0.0032 17.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 OAP57586.1 - 0.0043 17.0 0.2 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 OAP57586.1 - 0.0078 15.1 0.4 0.02 13.7 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 OAP57586.1 - 0.011 16.1 0.1 0.063 13.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP57586.1 - 0.025 13.0 0.5 0.042 12.3 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 OAP57586.1 - 0.09 11.6 0.4 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 OAP57586.1 - 0.095 11.7 0.0 0.98 8.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Aa_trans PF01490.13 OAP57587.1 - 6e-46 156.7 33.2 6.8e-46 156.5 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 OAP57587.1 - 0.0049 15.7 17.4 0.0049 15.7 12.1 2.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family FAD_binding_3 PF01494.14 OAP57588.1 - 1.3e-19 70.4 0.0 9.3e-19 67.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP57588.1 - 2.8e-09 36.3 0.3 3.6e-05 22.8 0.8 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP57588.1 - 9.1e-08 32.0 0.3 3e-07 30.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 OAP57588.1 - 1.1e-07 31.2 0.0 1.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP57588.1 - 4.2e-06 27.0 0.5 0.00083 19.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP57588.1 - 7.2e-06 25.0 5.0 1.3e-05 24.3 3.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP57588.1 - 1.3e-05 25.2 1.3 0.00011 22.2 1.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP57588.1 - 2.4e-05 22.9 0.3 0.00054 18.5 0.7 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 OAP57588.1 - 0.00015 20.9 1.3 0.00025 20.2 0.9 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 OAP57588.1 - 0.0022 16.9 4.6 0.004 16.0 3.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAP57588.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP57588.1 - 0.0068 15.0 2.5 2.5 6.6 0.0 2.1 1 1 0 2 2 2 2 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 OAP57588.1 - 0.034 13.8 0.4 0.08 12.6 0.3 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 OAP57588.1 - 0.082 12.4 1.1 0.14 11.6 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Strep_67kDa_ant PF06100.6 OAP57588.1 - 0.087 11.1 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family 3HCDH_N PF02737.13 OAP57588.1 - 0.096 12.3 1.6 0.17 11.5 1.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 OAP57588.1 - 0.099 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase UDPG_MGDP_dh_N PF03721.9 OAP57588.1 - 0.11 11.8 0.3 0.22 10.8 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.7 OAP57588.1 - 0.15 10.9 0.4 1.2 7.9 0.7 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein bZIP_1 PF00170.16 OAP57590.1 - 9.4e-07 28.7 14.2 1.1e-06 28.5 8.1 2.0 1 1 1 2 2 2 1 bZIP transcription factor SlyX PF04102.7 OAP57590.1 - 0.00015 22.0 3.7 0.00015 22.0 2.6 1.5 1 1 0 1 1 1 1 SlyX bZIP_2 PF07716.10 OAP57590.1 - 0.00027 20.6 17.2 0.00071 19.3 7.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 OAP57590.1 - 0.0004 20.6 10.6 0.00042 20.5 6.7 1.5 2 0 0 2 2 1 1 bZIP Maf transcription factor Shugoshin_N PF07558.6 OAP57590.1 - 0.0018 17.9 1.1 0.19 11.4 0.5 2.3 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region TBPIP PF07106.8 OAP57590.1 - 0.0078 15.7 2.0 0.011 15.2 1.4 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 OAP57590.1 - 0.043 12.4 3.0 0.054 12.1 2.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.7 OAP57590.1 - 0.048 11.4 3.8 0.056 11.2 2.6 1.1 1 0 0 1 1 1 0 HOOK protein Tup_N PF08581.5 OAP57590.1 - 0.051 13.7 1.1 0.094 12.9 0.8 1.5 1 0 0 1 1 1 0 Tup N-terminal IncA PF04156.9 OAP57590.1 - 0.067 12.7 9.9 0.093 12.3 6.9 1.2 1 0 0 1 1 1 0 IncA protein Sec34 PF04136.10 OAP57590.1 - 0.079 12.6 0.4 0.092 12.4 0.3 1.2 1 0 0 1 1 1 0 Sec34-like family DUF724 PF05266.9 OAP57590.1 - 0.09 12.3 2.9 0.11 12.1 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fmp27_WPPW PF10359.4 OAP57590.1 - 0.098 11.0 0.9 0.095 11.1 0.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GAS PF13851.1 OAP57590.1 - 0.1 11.7 3.7 0.14 11.3 2.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cortex-I_coil PF09304.5 OAP57590.1 - 0.1 12.6 4.9 0.17 11.9 3.4 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil IL2 PF00715.12 OAP57590.1 - 0.11 12.1 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Interleukin 2 Tmemb_cc2 PF10267.4 OAP57590.1 - 0.12 10.9 4.9 0.15 10.5 3.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2400 PF09674.5 OAP57590.1 - 0.14 11.8 0.4 0.17 11.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) CHD5 PF04420.9 OAP57590.1 - 0.16 11.5 0.8 0.21 11.2 0.6 1.3 1 0 0 1 1 1 0 CHD5-like protein DUF1383 PF07134.6 OAP57590.1 - 0.17 10.7 0.3 0.2 10.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) Striatin PF08232.7 OAP57590.1 - 0.18 12.1 4.5 0.22 11.8 3.1 1.2 1 0 0 1 1 1 0 Striatin family Fib_alpha PF08702.5 OAP57590.1 - 0.21 11.6 2.1 0.29 11.2 1.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WD40_alt PF14077.1 OAP57590.1 - 0.23 11.0 4.2 1.4 8.6 0.1 2.5 1 1 1 2 2 2 0 Alternative WD40 repeat motif Atg14 PF10186.4 OAP57590.1 - 0.42 9.5 6.1 0.46 9.3 4.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med9 PF07544.8 OAP57590.1 - 1.1 8.9 5.4 0.71 9.6 1.5 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 H-kinase_dim PF02895.9 OAP57590.1 - 2.4 8.5 4.8 3.7 7.9 1.6 2.3 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DivIC PF04977.10 OAP57590.1 - 4.1 6.9 7.8 1.3 8.5 1.5 2.2 1 1 1 2 2 2 0 Septum formation initiator Fungal_trans_2 PF11951.3 OAP57591.1 - 0.0096 14.5 0.0 0.18 10.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain vMSA PF00695.14 OAP57591.1 - 8.9 5.4 7.5 22 4.1 5.0 1.8 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus BRO1 PF03097.13 OAP57592.1 - 2.2e-109 365.6 0.2 1.5e-108 362.9 0.0 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 OAP57592.1 - 4.5e-81 272.0 12.3 4.5e-81 272.0 8.5 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Aldolase_II PF00596.16 OAP57593.1 - 3.1e-49 167.0 0.6 4e-49 166.7 0.4 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ferric_reduct PF01794.14 OAP57595.1 - 2.4e-17 63.1 11.6 2.4e-17 63.1 8.1 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 OAP57595.1 - 3.1e-14 52.7 0.0 6.2e-12 45.3 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAP57595.1 - 5.5e-13 49.1 0.1 1.1e-07 31.8 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Neurensin PF14927.1 OAP57595.1 - 0.056 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Neurensin ADH_N PF08240.7 OAP57596.1 - 2.3e-06 27.3 0.0 5.1e-05 22.9 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP57596.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Ank_2 PF12796.2 OAP57597.1 - 2.2e-39 133.6 0.1 1e-15 57.8 0.0 5.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP57597.1 - 2.9e-29 100.4 0.6 1.5e-08 34.6 0.0 6.7 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP57597.1 - 5.4e-29 100.0 0.0 3.8e-07 30.4 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 OAP57597.1 - 1.2e-28 97.4 0.2 1.2e-05 24.8 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 OAP57597.1 - 8.1e-25 84.4 0.0 0.00069 19.6 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat NACHT PF05729.7 OAP57597.1 - 0.001 18.7 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 OAP57597.1 - 0.0095 16.7 0.0 0.059 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MFS_1 PF07690.11 OAP57598.1 - 7.4e-52 176.2 53.6 1.2e-51 175.4 36.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AA_permease_C PF13906.1 OAP57598.1 - 0.026 14.3 0.8 0.026 14.3 0.6 4.0 4 0 0 4 4 4 0 C-terminus of AA_permease Ank_2 PF12796.2 OAP57599.1 - 1.1e-09 38.4 0.1 4.1e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP57599.1 - 3.6e-09 36.5 0.0 0.02 15.1 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 OAP57599.1 - 1.1e-08 34.4 0.0 0.00083 19.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAP57599.1 - 2.1e-08 33.6 0.0 0.0085 16.2 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAP57599.1 - 8.6e-06 26.1 0.9 0.0018 18.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) GTP_EFTU PF00009.22 OAP57600.1 - 1.3e-57 194.2 0.0 2e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAP57600.1 - 1.3e-36 124.7 0.1 4.6e-36 122.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAP57600.1 - 5.9e-17 61.5 1.9 5.9e-17 61.5 1.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TFIIS_C PF01096.13 OAP57600.1 - 2.8e-11 42.8 0.2 2.8e-11 42.8 0.1 2.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) GTP_EFTU_D4 PF14578.1 OAP57600.1 - 0.00061 19.3 1.9 0.00061 19.3 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 OAP57600.1 - 0.00088 19.2 0.3 0.0023 17.8 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_POL_M_15KD PF02150.11 OAP57600.1 - 0.0014 18.2 3.4 0.0041 16.7 2.4 1.8 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit adh_short_C2 PF13561.1 OAP57601.1 - 1.4e-20 74.1 0.0 1.8e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57601.1 - 2.3e-17 63.4 0.0 3.5e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57601.1 - 0.00061 19.5 0.2 0.002 17.8 0.1 1.8 1 1 0 1 1 1 1 KR domain Annexin PF00191.15 OAP57602.1 - 4e-17 61.8 0.1 0.0017 18.1 0.0 4.7 4 0 0 4 4 4 4 Annexin ABC1 PF03109.11 OAP57603.1 - 6.6e-23 80.9 0.0 1.5e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family CobW_C PF07683.9 OAP57603.1 - 0.054 13.2 0.1 0.24 11.1 0.0 2.1 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain BSP_II PF05432.6 OAP57604.1 - 0.41 9.8 15.2 0.66 9.1 10.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 OAP57604.1 - 8.8 6.8 10.4 0.23 11.9 2.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein His_Phos_1 PF00300.17 OAP57605.1 - 3.1e-14 53.3 0.0 9.1e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_transf_25 PF01755.12 OAP57605.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) APH PF01636.18 OAP57606.1 - 0.00039 20.2 0.8 0.0008 19.2 0.6 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF347 PF03988.7 OAP57607.1 - 0.034 14.0 0.7 0.034 14.0 0.5 1.8 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) SKG6 PF08693.5 OAP57607.1 - 0.04 13.2 0.1 0.04 13.2 0.1 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF1761 PF08570.5 OAP57607.1 - 0.47 10.4 4.4 0.1 12.5 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) Nucleoside_tran PF01733.13 OAP57608.1 - 3.3e-52 177.5 3.9 5.8e-52 176.7 2.7 1.3 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.11 OAP57608.1 - 1.8e-10 40.0 27.5 0.0014 17.4 3.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3635 PF12330.3 OAP57609.1 - 0.00082 19.3 0.0 0.0066 16.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 OAP57609.1 - 0.02 14.0 0.0 0.068 12.3 0.0 1.8 2 1 0 2 2 2 0 Protein kinase domain DUF946 PF06101.6 OAP57611.1 - 5.9e-18 64.1 2.7 1.3e-14 53.1 0.2 2.6 3 0 0 3 3 3 2 Plant protein of unknown function (DUF946) DUF2062 PF09835.4 OAP57611.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) HMG_box PF00505.14 OAP57614.1 - 2.4e-05 24.5 0.6 4.4e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Cpn60_TCP1 PF00118.19 OAP57615.1 - 1e-133 446.5 5.4 8.8e-133 443.4 3.7 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RXT2_N PF08595.6 OAP57615.1 - 0.003 17.3 4.3 0.0065 16.2 3.0 1.5 1 0 0 1 1 1 1 RXT2-like, N-terminal Pox_Ag35 PF03286.9 OAP57615.1 - 0.071 12.6 5.0 0.019 14.4 1.4 1.6 2 0 0 2 2 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 OAP57615.1 - 0.14 10.9 1.1 0.28 9.9 0.8 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein BTV_NS2 PF04514.7 OAP57615.1 - 0.14 11.0 3.4 0.24 10.2 2.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nucleo_P87 PF07267.6 OAP57615.1 - 0.25 9.9 3.5 0.13 10.9 0.6 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Sporozoite_P67 PF05642.6 OAP57615.1 - 0.37 8.6 6.6 0.58 7.9 4.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3295 PF11702.3 OAP57615.1 - 0.5 9.2 6.1 0.94 8.3 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF2457 PF10446.4 OAP57615.1 - 0.78 8.4 17.0 1.4 7.5 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 OAP57615.1 - 1 9.0 11.8 1.7 8.3 8.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 OAP57615.1 - 1.5 7.9 9.1 2.5 7.2 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 OAP57615.1 - 2.1 8.0 6.1 5.6 6.6 4.1 1.8 2 0 0 2 2 2 0 FAM176 family RRN3 PF05327.6 OAP57615.1 - 4.8 5.1 4.7 8.1 4.4 3.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 OAP57615.1 - 8.3 4.7 11.3 13 4.1 7.8 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAP57615.1 - 9 4.0 14.7 13 3.4 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 OAP57615.1 - 9.7 5.7 13.6 4.1 6.9 6.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Aminotran_3 PF00202.16 OAP57616.1 - 6.7e-77 258.6 0.0 8e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 OAP57616.1 - 0.046 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DHDPS PF00701.17 OAP57617.1 - 3e-40 137.6 0.0 3.7e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family p450 PF00067.17 OAP57618.1 - 3e-43 148.0 0.0 4e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SSF PF00474.12 OAP57619.1 - 3.3e-16 58.9 32.0 5.2e-16 58.2 22.0 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family adh_short PF00106.20 OAP57620.1 - 8.2e-22 77.8 0.3 9.9e-22 77.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57620.1 - 4.8e-12 45.9 0.1 6.9e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP57620.1 - 1.5e-08 34.6 0.0 1.8e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP57620.1 - 0.0016 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP57620.1 - 0.02 13.6 0.1 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAP57620.1 - 0.026 13.4 0.4 0.12 11.1 0.3 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 OAP57621.1 - 4.2e-14 52.0 0.3 5.4e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-AD PF07776.10 OAP57621.1 - 0.22 11.5 1.7 4.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Fungal_trans PF04082.13 OAP57622.1 - 1.7e-20 72.9 1.5 2.6e-20 72.3 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAT PF03417.11 OAP57623.1 - 6.1e-28 97.8 0.0 8.2e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 OAP57623.1 - 0.00032 20.9 0.0 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Amidohydro_1 PF01979.15 OAP57624.1 - 9.6e-18 64.9 1.0 1.3e-16 61.1 0.7 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAP57624.1 - 2e-10 41.1 5.4 8e-10 39.2 3.8 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 OAP57624.1 - 5.8e-10 38.8 0.0 1.5e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP57624.1 - 6.8e-06 25.5 3.1 0.0031 16.7 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Aldo_ket_red PF00248.16 OAP57625.1 - 1.8e-43 148.4 0.0 2.4e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aminotran_3 PF00202.16 OAP57626.1 - 4.1e-82 275.7 0.0 5.6e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III p450 PF00067.17 OAP57626.1 - 6.8e-47 160.0 0.0 9.7e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Beta_elim_lyase PF01212.16 OAP57626.1 - 3.8e-06 26.2 0.0 6.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase MdcG PF10620.4 OAP57626.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Aminotran_1_2 PF00155.16 OAP57626.1 - 0.17 10.7 0.0 0.59 9.0 0.0 2.0 2 1 0 2 2 2 0 Aminotransferase class I and II Amidase PF01425.16 OAP57627.1 - 5.5e-99 331.9 0.0 6.3e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 OAP57628.1 - 3.4e-33 114.8 28.9 4.5e-33 114.4 20.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Voltage_CLC PF00654.15 OAP57629.1 - 3.6e-87 292.6 33.4 4e-86 289.2 22.5 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 OAP57629.1 - 2.6e-07 30.2 0.0 0.0012 18.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain PH_10 PF15411.1 OAP57630.1 - 7.4e-23 80.9 0.1 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 OAP57630.1 - 5.9e-08 32.4 4.0 1.2e-07 31.3 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 OAP57630.1 - 2.2e-06 27.5 0.0 4.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 OAP57630.1 - 3e-06 27.0 0.0 1.3e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 OAP57630.1 - 0.00023 20.8 3.5 0.00044 19.9 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAP57630.1 - 0.00026 20.9 3.3 0.00054 19.9 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP57630.1 - 0.00037 20.1 0.9 0.00064 19.3 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP57630.1 - 0.0014 18.2 3.3 0.0028 17.2 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 OAP57630.1 - 0.0062 16.5 4.1 0.011 15.7 2.9 1.4 1 0 0 1 1 1 1 RING-like domain zf-rbx1 PF12678.2 OAP57630.1 - 0.017 15.1 0.9 0.039 14.0 0.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger AAA_5 PF07728.9 OAP57631.1 - 1.7e-126 416.5 0.0 1.8e-22 79.5 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAP57631.1 - 7.5e-31 106.4 0.0 3.8e-12 45.9 0.0 7.5 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 OAP57631.1 - 3.2e-28 98.5 0.0 3.8e-05 23.8 0.0 7.2 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAP57631.1 - 2.6e-20 73.4 3.0 9.4e-05 23.2 0.0 7.6 7 0 0 7 7 6 3 AAA domain AAA_16 PF13191.1 OAP57631.1 - 9.6e-20 71.3 23.2 9.1e-05 22.5 0.1 9.3 8 2 1 9 9 7 5 AAA ATPase domain AAA_22 PF13401.1 OAP57631.1 - 2.9e-18 66.2 0.0 0.031 14.4 0.0 7.7 7 0 0 7 7 6 2 AAA domain AAA_33 PF13671.1 OAP57631.1 - 8.7e-18 64.5 0.0 0.0048 16.7 0.0 7.4 6 1 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.1 OAP57631.1 - 2.1e-17 63.4 0.6 0.0039 17.2 0.0 8.0 8 0 0 8 8 7 2 Sigma-54 interaction domain AAA_14 PF13173.1 OAP57631.1 - 3.1e-17 62.6 0.0 0.0043 16.9 0.0 7.8 8 0 0 8 8 7 3 AAA domain Sigma54_activat PF00158.21 OAP57631.1 - 3.8e-16 59.0 0.0 0.023 14.1 0.0 7.0 7 0 0 7 7 7 3 Sigma-54 interaction domain AAA_18 PF13238.1 OAP57631.1 - 2.8e-14 53.5 17.1 0.00059 20.1 0.0 8.0 8 0 0 8 8 6 3 AAA domain AAA_19 PF13245.1 OAP57631.1 - 6e-14 51.5 7.4 0.054 13.2 0.0 6.9 6 0 0 6 6 6 3 Part of AAA domain UPF0079 PF02367.12 OAP57631.1 - 8.1e-14 51.3 0.9 0.3 10.7 0.0 6.6 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 OAP57631.1 - 1.2e-13 50.6 1.1 0.54 9.1 0.0 6.4 6 0 0 6 6 6 3 Type II/IV secretion system protein Zeta_toxin PF06414.7 OAP57631.1 - 1.4e-13 50.4 1.2 0.14 11.1 0.0 7.4 8 0 0 8 8 8 2 Zeta toxin ABC_tran PF00005.22 OAP57631.1 - 4.2e-13 49.7 0.7 0.051 13.8 0.0 6.4 6 0 0 6 6 6 3 ABC transporter Miro PF08477.8 OAP57631.1 - 7.5e-12 45.7 0.9 2.3 8.7 0.0 6.6 6 0 0 6 6 6 1 Miro-like protein Mg_chelatase PF01078.16 OAP57631.1 - 1.1e-11 44.2 1.0 2.7 7.0 0.0 8.7 8 2 2 10 10 9 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 OAP57631.1 - 2.8e-11 43.3 4.8 0.036 13.7 0.1 6.0 6 0 0 6 6 5 2 NACHT domain RNA_helicase PF00910.17 OAP57631.1 - 5.2e-11 42.6 0.9 3.3 7.9 0.0 6.6 6 0 0 6 6 6 0 RNA helicase DUF258 PF03193.11 OAP57631.1 - 1e-10 41.0 0.3 0.051 12.7 0.0 5.7 6 0 0 6 6 6 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAP57631.1 - 3.6e-10 39.1 0.9 0.28 10.7 0.0 6.3 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_28 PF13521.1 OAP57631.1 - 1.1e-09 38.5 3.4 0.048 13.6 0.0 6.7 6 0 0 6 6 6 1 AAA domain RuvB_N PF05496.7 OAP57631.1 - 1.8e-09 37.0 0.3 0.65 8.9 0.0 5.9 6 0 0 6 6 6 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 OAP57631.1 - 8.7e-09 35.4 0.0 1.6 8.4 0.0 6.0 6 0 0 6 6 6 1 Archaeal ATPase IstB_IS21 PF01695.12 OAP57631.1 - 9.2e-09 34.9 0.1 0.21 10.9 0.0 5.5 5 0 0 5 5 5 2 IstB-like ATP binding protein AAA_25 PF13481.1 OAP57631.1 - 1.9e-08 33.9 0.1 1.8 7.8 0.0 5.5 6 0 0 6 6 4 2 AAA domain MobB PF03205.9 OAP57631.1 - 2.9e-08 33.5 1.2 0.25 11.0 0.0 5.8 6 0 0 6 6 5 2 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 OAP57631.1 - 3.8e-08 32.9 0.8 0.41 10.1 0.0 5.6 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 OAP57631.1 - 4.8e-06 26.3 6.7 2.2 7.9 0.2 5.5 5 0 0 5 5 5 1 NTPase TIP49 PF06068.8 OAP57631.1 - 7.8e-06 24.8 1.4 0.014 14.1 0.0 5.0 6 0 0 6 6 6 1 TIP49 C-terminus CPT PF07931.7 OAP57631.1 - 6.7e-05 22.5 1.6 1.7 8.2 0.0 5.8 5 1 0 5 5 5 1 Chloramphenicol phosphotransferase-like protein cobW PF02492.14 OAP57631.1 - 0.00015 21.2 5.1 1.1 8.6 0.0 5.3 6 0 0 6 6 5 1 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 OAP57631.1 - 0.00018 20.8 1.3 2.2 7.4 0.0 4.3 4 0 0 4 4 4 1 PhoH-like protein SRP54 PF00448.17 OAP57631.1 - 0.00058 19.3 3.1 6.2 6.2 0.1 5.0 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain Bac_DnaA PF00308.13 OAP57631.1 - 0.00059 19.5 0.0 6.7 6.2 0.0 4.5 5 0 0 5 5 4 0 Bacterial dnaA protein MMR_HSR1 PF01926.18 OAP57631.1 - 0.00061 19.7 0.3 16 5.4 0.0 5.8 7 0 0 7 7 6 0 50S ribosome-binding GTPase SRPRB PF09439.5 OAP57631.1 - 0.0016 17.6 1.2 4.7 6.4 0.0 5.3 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit Syntaxin PF00804.20 OAP57631.1 - 0.002 18.2 0.0 10 6.3 0.0 4.5 4 1 0 4 4 2 0 Syntaxin Rad17 PF03215.10 OAP57631.1 - 0.0023 16.7 0.4 1.9 7.0 0.0 3.9 5 0 0 5 5 4 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 OAP57631.1 - 0.003 17.1 0.9 0.74 9.3 0.0 3.9 5 0 0 5 5 3 1 AAA domain ResIII PF04851.10 OAP57631.1 - 0.0045 16.8 3.4 14 5.4 0.0 5.2 6 0 0 6 6 4 0 Type III restriction enzyme, res subunit HCV_NS4b PF01001.14 OAP57631.1 - 0.006 15.9 0.0 1.2 8.4 0.0 2.5 2 0 0 2 2 2 1 Hepatitis C virus non-structural protein NS4b CbiA PF01656.18 OAP57631.1 - 0.0082 15.5 0.4 5.8 6.2 0.0 3.6 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_6 PF12774.2 OAP57631.1 - 0.023 14.2 0.2 20 4.6 0.0 4.6 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_21 PF13304.1 OAP57631.1 - 0.034 14.1 0.0 0.93 9.3 0.0 3.2 4 0 0 4 4 2 0 AAA domain ATP_bind_1 PF03029.12 OAP57631.1 - 0.042 13.3 10.0 2.6 7.5 0.1 5.5 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 OAP57631.1 - 0.049 13.1 0.1 32 3.9 0.1 3.7 4 1 0 5 5 5 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.2 OAP57631.1 - 0.069 12.2 0.2 28 3.6 0.0 4.2 5 0 0 5 5 5 0 P-loop containing dynein motor region D3 Guanylate_kin PF00625.16 OAP57631.1 - 0.12 11.7 0.2 50 3.2 0.0 3.8 4 0 0 4 4 3 0 Guanylate kinase DUF927 PF06048.6 OAP57631.1 - 0.12 11.5 0.9 0.79 8.9 0.1 2.7 4 0 0 4 4 3 0 Domain of unknown function (DUF927) NB-ARC PF00931.17 OAP57631.1 - 0.13 11.0 2.5 20 3.9 0.0 4.1 4 0 0 4 4 4 0 NB-ARC domain KaiC PF06745.8 OAP57631.1 - 0.21 10.6 1.1 42 3.1 0.0 4.4 5 0 0 5 5 5 0 KaiC Polyoma_lg_T_C PF06431.6 OAP57631.1 - 0.43 9.1 0.0 13 4.3 0.0 2.9 3 0 0 3 3 3 0 Polyomavirus large T antigen C-terminus Solute_trans_a PF03619.11 OAP57631.1 - 7 5.8 0.0 12 5.0 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter Ostalpha PRCC PF10253.4 OAP57633.1 - 1.6e-35 123.4 1.9 1.6e-35 123.4 1.3 3.1 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Peptidase_M48 PF01435.13 OAP57634.1 - 1.3e-32 113.2 0.0 1.9e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 adh_short PF00106.20 OAP57635.1 - 9.6e-25 87.4 0.1 2.8e-24 85.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57635.1 - 4.1e-20 72.5 0.0 7.1e-20 71.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP57635.1 - 3.2e-13 49.7 0.0 5.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP57635.1 - 0.00031 20.2 0.0 0.0006 19.3 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PHY PF00360.15 OAP57635.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Phytochrome region Polysacc_synt_2 PF02719.10 OAP57635.1 - 0.14 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 OAP57635.1 - 0.76 9.6 3.4 0.38 10.5 0.6 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 OAP57636.1 - 1.5e-16 60.1 2.7 2.6e-16 59.3 1.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57636.1 - 1.2e-05 25.0 13.2 2.1e-05 24.3 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EBP PF05241.7 OAP57637.1 - 5e-63 211.6 2.4 5.9e-63 211.3 1.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein Acetyltransf_7 PF13508.1 OAP57638.1 - 2.1e-09 37.3 0.0 5.3e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP57638.1 - 3.4e-09 36.5 0.0 8.7e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP57638.1 - 0.00024 21.1 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP57638.1 - 0.00034 20.4 0.0 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 OAP57639.1 - 1.4e-103 346.9 21.5 1.7e-103 346.6 14.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57639.1 - 5.6e-26 91.0 31.4 4.8e-25 88.0 17.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP57639.1 - 8.1e-06 24.4 0.1 8.1e-06 24.4 0.1 3.6 3 1 0 4 4 4 2 MFS/sugar transport protein zf-RING_2 PF13639.1 OAP57640.1 - 2.1e-07 30.6 8.8 2.1e-07 30.6 6.1 3.8 5 0 0 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.20 OAP57640.1 - 2.6e-07 30.2 7.5 2.6e-07 30.2 5.2 4.8 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP57640.1 - 2.8e-06 27.2 7.6 2.8e-06 27.2 5.3 4.3 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 OAP57640.1 - 0.00026 20.5 0.1 0.00026 20.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_6 PF14835.1 OAP57640.1 - 0.00068 19.3 1.2 0.00068 19.3 0.9 3.4 4 1 0 4 4 4 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 OAP57640.1 - 0.0007 19.4 7.1 0.0007 19.4 4.9 3.8 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAP57640.1 - 0.0038 16.9 3.1 0.011 15.4 2.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger SH3_1 PF00018.23 OAP57640.1 - 0.0081 15.5 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAP57640.1 - 0.029 13.8 0.6 0.08 12.4 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain Zn_clus PF00172.13 OAP57641.1 - 1.5e-07 31.1 9.4 2.5e-07 30.4 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP57642.1 - 1.6e-37 129.0 52.8 1.6e-37 129.0 36.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP57642.1 - 1.7e-14 52.9 13.5 1.7e-14 52.9 9.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAP57642.1 - 8.4e-11 41.1 12.8 8.4e-11 41.1 8.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.13 OAP57643.1 - 1.3e-24 86.4 0.0 2.4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57643.1 - 7.1e-08 32.2 12.9 1.6e-07 31.1 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CMD PF02627.15 OAP57644.1 - 3e-21 75.0 0.1 5.5e-21 74.1 0.0 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Lactamase_B_2 PF12706.2 OAP57645.1 - 2.4e-08 33.7 1.1 3.4e-08 33.2 0.8 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAP57645.1 - 7e-06 25.8 6.3 1.5e-05 24.7 4.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 OAP57645.1 - 0.0089 15.7 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NAD_binding_2 PF03446.10 OAP57646.1 - 4.8e-35 120.8 0.0 6.3e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP57646.1 - 3.1e-16 59.5 0.0 4.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 OAP57646.1 - 0.0072 16.7 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 OAP57646.1 - 0.063 13.8 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ldh_2 PF02615.9 OAP57647.1 - 1e-57 195.4 0.0 1.2e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase MFS_1 PF07690.11 OAP57648.1 - 1.4e-30 106.2 28.4 1.4e-30 106.2 19.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_2 PF00890.19 OAP57649.1 - 5.9e-38 130.8 0.1 3.9e-37 128.1 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAP57649.1 - 1.3e-07 31.1 0.0 2.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 OAP57649.1 - 5.3e-07 28.8 2.0 9.6e-07 28.0 0.3 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP57649.1 - 1.9e-06 27.8 0.1 0.00012 22.0 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP57649.1 - 2.9e-06 26.0 0.9 0.0038 15.7 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 OAP57649.1 - 8.2e-06 26.0 0.1 0.051 13.6 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP57649.1 - 0.00017 20.5 2.0 0.00037 19.4 0.2 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 OAP57649.1 - 0.00038 20.4 0.4 0.0017 18.3 0.1 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP57649.1 - 0.0098 14.8 0.0 0.059 12.2 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 OAP57649.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 OAP57649.1 - 0.059 13.2 0.2 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 ThiF family Thi4 PF01946.12 OAP57649.1 - 0.065 12.3 0.1 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Aldedh PF00171.17 OAP57650.1 - 2.6e-145 484.2 0.0 3e-145 484.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 OAP57650.1 - 0.22 10.7 0.0 0.94 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ADH_N PF08240.7 OAP57651.1 - 1.2e-27 95.8 1.6 2.2e-27 94.9 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP57651.1 - 2.7e-19 68.9 0.0 5.1e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 OAP57651.1 - 6.3e-05 22.5 0.0 0.00028 20.4 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Methyltransf_31 PF13847.1 OAP57651.1 - 0.039 13.5 0.0 0.091 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 OAP57652.1 - 1.4e-12 47.9 0.0 1.8e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP57652.1 - 3.7e-05 23.5 0.0 0.00016 21.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Nitroreductase PF00881.19 OAP57653.1 - 2.3e-15 56.8 0.0 2.8e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.11 OAP57655.1 - 1.5e-36 125.8 29.2 1.5e-36 125.8 20.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 OAP57655.1 - 0.2 12.0 4.2 0.29 11.5 0.1 2.9 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peptidase_M20 PF01546.23 OAP57656.1 - 4.4e-26 91.5 0.2 6.2e-26 91.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 OAP57656.1 - 0.0033 17.2 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 OAP57656.1 - 0.11 12.2 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase dimerisation domain E1-E2_ATPase PF00122.15 OAP57657.1 - 4.8e-46 156.6 5.8 4.8e-46 156.6 4.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 OAP57657.1 - 8.6e-27 94.9 2.0 1.6e-26 94.1 1.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAP57657.1 - 1.8e-14 54.3 0.0 4.6e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 OAP57657.1 - 0.03 14.4 0.0 0.092 12.9 0.0 1.9 1 0 0 1 1 1 0 Heavy-metal-associated domain Hydrolase_3 PF08282.7 OAP57657.1 - 0.16 11.5 0.1 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 OAP57658.1 - 1.4e-41 142.4 100.9 2.4e-38 131.7 44.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WBP-1 PF11669.3 OAP57658.1 - 4.3 7.4 4.8 0.71 9.9 0.1 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 Fungal_trans_2 PF11951.3 OAP57660.1 - 1.2e-42 145.8 0.4 1.6e-42 145.4 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57660.1 - 0.00019 21.2 10.5 0.00019 21.2 7.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamin_N PF00350.18 OAP57661.1 - 6.3e-26 91.1 0.0 1.3e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 OAP57661.1 - 0.0038 17.1 0.0 0.017 15.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 OAP57661.1 - 0.0042 16.9 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Miro PF08477.8 OAP57661.1 - 0.0092 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Nucleoporin_FG PF13634.1 OAP57661.1 - 0.12 12.5 43.4 43 4.3 30.1 3.1 1 1 0 1 1 1 0 Nucleoporin FG repeat region DUF2155 PF09923.4 OAP57661.1 - 0.12 12.4 0.0 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) AAA_21 PF13304.1 OAP57661.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 OAP57662.1 - 6.3e-19 67.8 0.0 1.1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 OAP57663.1 - 1.4e-47 161.9 0.0 1.7e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 OAP57664.1 - 4e-69 233.3 18.2 4.8e-69 233.0 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57664.1 - 4.9e-17 61.6 24.0 8.8e-10 37.8 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.1 OAP57665.1 - 1.2e-53 182.2 0.0 1.6e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain OprD PF03573.8 OAP57665.1 - 0.074 11.8 0.0 25 3.4 0.0 2.9 3 0 0 3 3 3 0 outer membrane porin, OprD family Fungal_trans PF04082.13 OAP57666.1 - 1.8e-13 49.9 3.9 3e-13 49.2 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP57666.1 - 1.1e-09 38.0 6.7 0.00015 21.8 0.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP57666.1 - 0.0001 22.3 15.4 0.0017 18.5 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger adh_short PF00106.20 OAP57667.1 - 2.6e-24 86.0 0.1 3.8e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57667.1 - 2.6e-13 50.2 0.0 4.6e-13 49.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP57667.1 - 7.5e-07 28.9 0.1 1.9e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 OAP57667.1 - 0.012 14.7 0.1 0.025 13.6 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.14 OAP57667.1 - 0.019 13.6 0.0 1.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ECH PF00378.15 OAP57668.1 - 2.1e-51 174.4 0.0 3.1e-51 173.8 0.0 1.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 OAP57668.1 - 0.0039 16.9 0.0 0.049 13.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 DUF3005 PF11448.3 OAP57668.1 - 0.048 13.2 0.2 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) AMP-binding PF00501.23 OAP57669.1 - 2.5e-52 177.6 0.0 3.7e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP57669.1 - 0.057 14.3 0.0 0.13 13.2 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain 4HBT PF03061.17 OAP57670.1 - 2.8e-10 40.1 0.0 4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 OAP57670.1 - 8.1e-06 26.2 0.0 1e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 OAP57670.1 - 0.002 17.1 0.2 0.0031 16.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Pyr_redox_3 PF13738.1 OAP57671.1 - 1e-26 94.2 0.1 1.8e-26 93.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP57671.1 - 3.6e-15 55.7 0.0 2.2e-12 46.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 OAP57671.1 - 8.1e-14 50.7 0.5 2.2e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP57671.1 - 2.6e-11 43.3 0.0 1.9e-09 37.4 0.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP57671.1 - 3.1e-09 37.0 0.0 4e-07 30.1 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP57671.1 - 1.8e-08 34.2 0.6 2.5e-06 27.3 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 OAP57671.1 - 1.8e-07 30.4 4.5 1.3e-06 27.5 2.8 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP57671.1 - 1.5e-06 28.5 0.3 0.01 16.1 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP57671.1 - 1.3e-05 24.4 0.1 0.00018 20.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 OAP57671.1 - 8.3e-05 22.7 0.0 0.12 12.6 0.0 2.8 3 0 0 3 3 3 2 Putative NAD(P)-binding Shikimate_DH PF01488.15 OAP57671.1 - 0.00028 20.9 0.1 0.36 10.9 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 OAP57671.1 - 0.0009 17.8 0.0 0.046 12.1 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 OAP57671.1 - 0.0013 17.6 0.0 0.0028 16.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP57671.1 - 0.0023 16.9 0.3 0.037 12.9 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 OAP57671.1 - 0.0087 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 OAP57671.1 - 0.023 14.5 0.1 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 OAP57671.1 - 0.075 11.8 0.1 13 4.5 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A adh_short_C2 PF13561.1 OAP57672.1 - 1.1e-27 97.3 0.0 1.3e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57672.1 - 2.5e-24 86.0 0.3 3.5e-24 85.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57672.1 - 6.3e-08 32.4 0.5 1.6e-07 31.2 0.4 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP57672.1 - 0.003 16.5 0.1 0.0044 15.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Arylesterase PF01731.15 OAP57673.1 - 3.8e-07 29.9 0.0 8.9e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Arylesterase SGL PF08450.7 OAP57673.1 - 0.00039 19.8 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 OAP57673.1 - 0.078 13.0 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Strictosidine synthase ABM PF03992.11 OAP57674.1 - 2e-11 43.7 0.2 2.5e-11 43.4 0.2 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase TPR_14 PF13428.1 OAP57674.1 - 0.035 14.7 0.4 0.079 13.6 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP57674.1 - 0.11 12.3 0.3 0.23 11.3 0.2 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.19 OAP57675.1 - 2.9e-84 283.2 21.3 3.3e-84 283.0 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57675.1 - 5.3e-20 71.4 32.1 1.1e-17 63.8 13.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.1 OAP57676.1 - 8.9e-17 61.6 0.5 3.1e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP57676.1 - 1e-12 48.1 0.0 2.3e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ppx-GppA PF02541.11 OAP57677.1 - 2.7e-43 148.1 0.0 8e-43 146.6 0.0 1.7 1 1 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 OAP57677.1 - 0.16 10.3 0.0 0.25 9.7 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DIOX_N PF14226.1 OAP57678.1 - 4.4e-29 101.3 0.0 6.9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP57678.1 - 7.6e-21 74.2 0.0 1.7e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 OAP57679.1 - 2.5e-91 306.4 39.4 2.9e-91 306.2 27.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LSM14 PF12701.2 OAP57681.1 - 7.9e-32 108.9 0.0 1.6e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 OAP57681.1 - 1.3e-18 67.4 5.1 1.3e-18 67.4 3.5 1.8 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 OAP57681.1 - 0.023 14.5 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain Mitofilin PF09731.4 OAP57681.1 - 0.19 10.3 5.4 0.26 9.8 3.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GRP PF07172.6 OAP57681.1 - 1.2 9.6 33.2 1.2 9.6 0.6 2.5 2 0 0 2 2 2 0 Glycine rich protein family WD40 PF00400.27 OAP57682.1 - 1.7e-17 62.5 15.2 0.00017 21.3 0.3 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 OAP57682.1 - 0.00024 19.3 0.2 0.052 11.6 0.2 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 OAP57682.1 - 0.046 13.1 1.3 0.22 10.9 0.1 2.3 2 1 0 2 2 2 0 PQQ-like domain Thioredox_DsbH PF03190.10 OAP57683.1 - 6e-65 217.9 0.0 9.9e-65 217.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 OAP57683.1 - 1.3e-08 34.7 0.0 3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.6 OAP57683.1 - 0.0017 17.4 0.2 0.26 10.2 0.0 2.5 2 1 1 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Thioredoxin_2 PF13098.1 OAP57683.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Epimerase PF01370.16 OAP57684.1 - 4.6e-08 32.7 0.0 3.4e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAP57684.1 - 0.0017 18.3 1.0 0.0094 15.8 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAP57684.1 - 0.002 18.1 0.4 0.0043 17.0 0.1 1.8 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP57684.1 - 0.0091 14.9 0.0 0.029 13.3 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein F420_oxidored PF03807.12 OAP57684.1 - 0.019 15.3 0.1 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 OAP57684.1 - 0.054 12.1 0.0 0.13 10.9 0.0 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 OAP57684.1 - 0.08 12.1 0.0 0.2 10.9 0.0 1.7 1 1 1 2 2 2 0 NmrA-like family PBP_sp32 PF07222.7 OAP57685.1 - 7.2 5.6 17.9 0.81 8.8 9.0 1.9 2 0 0 2 2 2 0 Proacrosin binding protein sp32 GST_N_3 PF13417.1 OAP57687.1 - 3.5e-10 39.9 0.0 6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP57687.1 - 3.2e-09 36.6 0.0 7.6e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP57687.1 - 6.7e-08 32.4 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAP57687.1 - 5.1e-05 23.3 0.0 9.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP57687.1 - 0.0036 17.1 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP57687.1 - 0.022 15.2 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 OAP57689.1 - 7.9e-21 74.1 0.4 1.9e-20 72.8 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain NDK PF00334.14 OAP57691.1 - 8.5e-55 184.2 0.0 9.6e-55 184.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 OAP57692.1 - 3.2e-150 500.8 6.3 4.1e-150 500.4 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 OAP57692.1 - 6.1e-26 90.0 2.8 7e-26 89.8 0.3 2.4 3 0 0 3 3 3 1 Galactose mutarotase-like Gp5_C PF06715.7 OAP57692.1 - 0.055 13.4 0.1 0.34 10.9 0.1 2.4 1 0 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) Alpha_GJ PF03229.8 OAP57693.1 - 0.0042 17.4 3.3 0.013 15.7 2.3 1.9 1 0 0 1 1 1 1 Alphavirus glycoprotein J PRCC PF10253.4 OAP57693.1 - 0.0076 16.9 0.8 0.01 16.5 0.5 1.3 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting SKG6 PF08693.5 OAP57693.1 - 0.065 12.5 0.9 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF4199 PF13858.1 OAP57693.1 - 0.19 11.6 2.0 0.93 9.4 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF1880 PF08976.6 OAP57693.1 - 1.1 9.4 4.7 1.9 8.6 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) PQ-loop PF04193.9 OAP57694.1 - 1.5e-24 85.3 6.7 3.2e-16 58.6 0.1 3.1 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 OAP57694.1 - 0.096 13.1 2.9 0.51 10.8 1.7 2.4 1 1 0 1 1 1 0 ER lumen protein retaining receptor AzlD PF05437.7 OAP57694.1 - 1.6 8.7 5.8 0.46 10.4 0.4 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) MFS_1 PF07690.11 OAP57697.1 - 3.4e-36 124.6 33.6 3.4e-36 124.6 23.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP57697.1 - 1.2e-09 36.9 6.3 1.8e-09 36.3 4.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2237 PF09996.4 OAP57698.1 - 3.2e-31 107.2 0.2 6.4e-31 106.2 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) ACBP PF00887.14 OAP57699.1 - 2.2e-24 84.9 0.0 1.3e-23 82.4 0.0 2.2 1 1 0 1 1 1 1 Acyl CoA binding protein MFS_1 PF07690.11 OAP57700.1 - 3e-39 134.7 25.7 3e-39 134.7 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP57701.1 - 4.2e-27 94.6 1.0 8.7e-27 93.6 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57701.1 - 6.7e-09 35.5 7.8 1.2e-08 34.7 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 OAP57702.1 - 5e-53 179.9 0.0 6.6e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP57702.1 - 6.7e-28 97.4 0.0 1e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP57702.1 - 3.1e-06 26.3 0.0 5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ank_2 PF12796.2 OAP57703.1 - 2.1e-62 207.4 6.1 9.1e-17 61.1 0.1 6.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 OAP57703.1 - 1.9e-57 188.3 18.9 6.5e-08 32.0 0.1 11.6 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.1 OAP57703.1 - 7.4e-41 137.2 12.0 1.3e-05 25.3 0.0 8.3 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP57703.1 - 9.6e-40 134.2 7.3 5.1e-07 30.0 0.0 8.6 3 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP57703.1 - 3.2e-39 129.0 5.6 2e-05 24.3 0.0 11.7 11 0 0 11 11 11 8 Ankyrin repeat AAA_16 PF13191.1 OAP57703.1 - 0.00024 21.1 0.0 0.0051 16.8 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP57703.1 - 0.0088 16.1 0.0 0.072 13.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.12 OAP57704.1 - 0.0026 16.8 0.0 0.076 12.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAP57704.1 - 0.0043 16.2 0.1 0.055 12.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain ADH_zinc_N PF00107.21 OAP57705.1 - 2.3e-13 49.8 0.1 1.1e-12 47.6 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP57705.1 - 3.4e-11 44.1 0.1 1.2e-10 42.3 0.0 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP57705.1 - 1.7e-09 37.3 0.0 6.6e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 OAP57705.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 OAP57705.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 OAP57705.1 - 0.14 11.3 0.1 0.32 10.1 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DEAD PF00270.24 OAP57706.1 - 1.6e-20 73.2 0.0 4.2e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 OAP57706.1 - 8.6e-20 71.3 0.0 1.9e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAP57706.1 - 1.7e-19 69.4 0.1 5.3e-19 67.8 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HUN PF08729.5 OAP57706.1 - 0.0071 16.1 3.6 0.024 14.5 2.5 1.9 1 0 0 1 1 1 1 HPC2 and ubinuclein domain AAA_22 PF13401.1 OAP57706.1 - 0.018 15.1 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF3277 PF11681.3 OAP57707.1 - 0.25 10.8 4.5 0.49 9.8 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Metallophos PF00149.23 OAP57708.1 - 1.7e-10 40.6 0.2 3.9e-10 39.4 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP57708.1 - 5.4e-09 36.0 0.0 7.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4286 PF14114.1 OAP57709.1 - 1.8 8.8 5.9 3.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) DUF1814 PF08843.6 OAP57711.1 - 0.00015 21.6 0.0 0.00022 21.0 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) Metallophos PF00149.23 OAP57712.1 - 2.6e-06 27.0 0.8 0.0085 15.5 0.1 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP57712.1 - 0.0022 17.8 0.1 0.029 14.2 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Suc_Fer-like PF06999.7 OAP57713.1 - 2.7e-43 148.6 0.0 7.3e-43 147.2 0.0 1.7 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Ring_hydroxyl_A PF00848.14 OAP57714.1 - 6.7e-36 123.8 0.5 1.9e-35 122.4 0.3 1.7 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 OAP57714.1 - 1.1e-15 56.9 0.0 2.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans_2 PF11951.3 OAP57715.1 - 6.7e-38 130.2 2.3 9.5e-38 129.7 1.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57715.1 - 0.032 14.1 0.6 0.032 14.1 0.4 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.16 OAP57716.1 - 9e-26 90.6 0.0 1.2e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sugar_tr PF00083.19 OAP57717.1 - 7.6e-129 430.1 30.3 8.7e-129 429.9 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57717.1 - 3.1e-25 88.6 52.6 9.2e-20 70.6 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RWD PF05773.17 OAP57718.1 - 1.3e-19 70.1 0.1 2.8e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 OAP57718.1 - 1.4e-18 66.5 37.5 1.9e-13 50.0 2.7 3.7 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 OAP57718.1 - 6.8e-05 22.6 10.8 6.8e-05 22.6 7.5 3.7 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAP57718.1 - 3.6 7.6 43.3 0.023 14.7 8.2 4.2 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) PAP2 PF01569.16 OAP57719.1 - 3.4e-14 52.6 2.5 3.4e-14 52.6 1.7 1.8 1 1 1 2 2 2 1 PAP2 superfamily DUF4203 PF13886.1 OAP57719.1 - 0.0016 17.9 6.1 0.059 12.8 0.9 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4203) DUF212 PF02681.9 OAP57719.1 - 0.0025 17.5 0.0 0.055 13.1 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family Tim17 PF02466.14 OAP57719.1 - 0.19 11.7 1.2 0.31 11.1 0.8 1.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family DUF202 PF02656.10 OAP57719.1 - 0.42 10.8 3.1 0.56 10.4 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4131 PF13567.1 OAP57719.1 - 7.5 5.9 10.2 7.5 5.9 4.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Abi PF02517.11 OAP57720.1 - 7.2e-13 48.4 13.3 7.2e-13 48.4 9.2 2.4 3 1 0 3 3 3 1 CAAX protease self-immunity DUF2371 PF10177.4 OAP57720.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Synaptobrevin PF00957.16 OAP57721.1 - 0.33 10.5 0.8 0.67 9.6 0.6 1.4 1 0 0 1 1 1 0 Synaptobrevin HET PF06985.6 OAP57722.1 - 0.0003 20.9 0.3 0.051 13.7 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ER_lumen_recept PF00810.13 OAP57724.1 - 8.8e-55 185.2 7.2 1.3e-54 184.6 5.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF485 PF04341.7 OAP57724.1 - 0.001 18.7 1.5 0.035 13.8 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF485 PQ-loop PF04193.9 OAP57724.1 - 3.2 7.3 15.0 4 7.0 0.1 4.0 5 0 0 5 5 5 0 PQ loop repeat amfpi-1 PF12190.3 OAP57725.1 - 0.11 13.0 0.4 0.37 11.3 0.1 2.0 2 0 0 2 2 2 0 Fungal protease inhibitor zf-H2C2 PF09337.5 OAP57726.1 - 0.0066 15.8 1.7 0.011 15.1 0.2 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger QRPTase_C PF01729.14 OAP57727.1 - 2.3e-54 183.4 0.2 2.8e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 OAP57727.1 - 1.6e-23 82.2 0.0 4.8e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.16 OAP57727.1 - 0.0052 15.8 0.4 0.011 14.7 0.1 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Phytoreo_P8 PF07124.6 OAP57727.1 - 0.0062 15.2 0.0 0.009 14.7 0.0 1.2 1 0 0 1 1 1 1 Phytoreovirus outer capsid protein P8 PhrC_PhrF PF11131.3 OAP57728.1 - 0.15 11.6 0.9 0.76 9.3 0.0 2.5 3 0 0 3 3 3 0 Rap-phr extracellular signalling WD40 PF00400.27 OAP57729.1 - 7.4e-15 54.1 10.6 0.0001 22.0 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Myb_DNA-bind_4 PF13837.1 OAP57729.1 - 4.3e-05 23.5 1.2 9.8e-05 22.4 0.8 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain eIF2A PF08662.6 OAP57729.1 - 0.014 15.0 0.0 9.3 5.9 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PUF PF00806.14 OAP57731.1 - 3.4e-38 126.9 4.2 1.1e-05 24.6 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat Spc7 PF08317.6 OAP57731.1 - 0.0081 14.8 4.7 0.012 14.2 3.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein RraB PF06877.6 OAP57731.1 - 0.016 15.8 0.3 2.7 8.7 0.0 3.1 2 1 1 3 3 3 0 Regulator of ribonuclease activity B HALZ PF02183.13 OAP57731.1 - 0.13 11.9 2.0 0.32 10.7 1.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4618 PF15397.1 OAP57731.1 - 0.36 10.1 9.7 0.61 9.3 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) IncA PF04156.9 OAP57731.1 - 1.3 8.6 8.8 2.1 7.8 6.1 1.2 1 0 0 1 1 1 0 IncA protein Peptidase_S9 PF00326.16 OAP57732.1 - 3.1e-09 36.3 0.4 5.4e-09 35.5 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP57732.1 - 3.3e-06 26.9 0.7 7.4e-06 25.7 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP57732.1 - 0.001 18.5 0.4 0.089 12.2 0.0 2.5 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.15 OAP57732.1 - 0.012 15.1 0.7 0.023 14.1 0.5 1.5 1 0 0 1 1 1 0 Putative esterase TPT PF03151.11 OAP57733.1 - 3.9e-34 117.5 4.5 3.9e-34 117.5 3.1 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 OAP57733.1 - 1.1e-06 28.7 27.5 0.0011 18.9 5.1 3.3 3 2 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 OAP57733.1 - 0.00013 21.0 17.0 0.0013 17.7 11.8 2.1 1 1 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 OAP57733.1 - 0.0041 16.0 0.4 0.0041 16.0 0.3 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) Nuc_sug_transp PF04142.10 OAP57733.1 - 0.0049 16.0 3.4 0.14 11.2 0.1 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter CDC50 PF03381.10 OAP57734.1 - 5.2e-100 334.1 0.0 6.4e-100 333.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Casein PF00363.13 OAP57734.1 - 0.014 16.0 1.3 0.014 16.0 0.9 1.9 2 0 0 2 2 2 0 Casein Peptidase_M43 PF05572.8 OAP57735.1 - 3.9e-11 42.7 1.0 2.4e-09 36.9 0.7 2.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 OAP57735.1 - 2.3e-06 27.6 8.7 5.3e-06 26.4 6.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 OAP57735.1 - 0.0091 16.0 5.1 0.01 15.9 2.9 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 OAP57735.1 - 0.011 15.2 0.7 0.022 14.3 0.5 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAP57735.1 - 0.028 14.9 1.5 0.12 12.9 1.1 2.1 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAP57735.1 - 0.035 13.8 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Matrixin Inhibitor_Mig-6 PF11555.3 OAP57735.1 - 0.099 13.0 0.1 0.099 13.0 0.1 2.9 4 0 0 4 4 4 0 EGFR receptor inhibitor Mig-6 Methyltransf_18 PF12847.2 OAP57736.1 - 6.2e-14 52.5 0.0 1e-13 51.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP57736.1 - 1.9e-13 50.2 0.0 1.7e-12 47.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP57736.1 - 7e-12 45.4 0.6 1.5e-11 44.3 0.4 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP57736.1 - 7.3e-11 42.4 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP57736.1 - 1.2e-10 41.7 0.0 8.9e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 OAP57736.1 - 2.5e-10 40.6 0.0 6.1e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP57736.1 - 4.9e-10 39.3 0.0 6.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP57736.1 - 2.9e-05 23.5 0.0 0.0068 15.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_32 PF13679.1 OAP57736.1 - 0.00013 21.6 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAP57736.1 - 0.00062 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 OAP57736.1 - 0.00082 18.5 0.0 0.0016 17.6 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 OAP57736.1 - 0.0026 17.7 0.0 0.0094 15.9 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.12 OAP57736.1 - 0.014 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Pox_MCEL PF03291.11 OAP57736.1 - 0.11 11.3 0.0 0.26 10.1 0.0 1.6 1 1 0 1 1 1 0 mRNA capping enzyme SKIP_SNW PF02731.10 OAP57737.1 - 1.3e-67 226.2 5.0 1.3e-67 226.2 3.5 2.6 3 0 0 3 3 3 1 SKIP/SNW domain DUF4603 PF15376.1 OAP57737.1 - 0.31 8.1 13.5 0.42 7.7 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FAM60A PF15396.1 OAP57737.1 - 1.5 8.5 10.2 3.6 7.2 7.1 1.7 1 0 0 1 1 1 0 Protein Family FAM60A COX17 PF05051.8 OAP57738.1 - 6.7e-20 70.8 7.7 9.1e-20 70.4 5.3 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 OAP57738.1 - 0.04 13.6 4.5 0.23 11.2 0.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 OAP57738.1 - 0.068 13.1 2.1 0.14 12.1 1.5 1.5 1 0 0 1 1 1 0 CHCH domain Sec10 PF07393.6 OAP57739.1 - 2.1e-205 684.0 0.0 2.6e-205 683.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Opi1 PF08618.5 OAP57740.1 - 2.6e-66 224.3 0.0 1.7e-44 152.4 0.0 3.2 1 1 2 3 3 3 3 Transcription factor Opi1 PSDC PF12588.3 OAP57741.1 - 9.6e-24 83.6 0.1 3.1e-20 72.2 0.0 2.2 1 1 1 2 2 2 2 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 OAP57741.1 - 6.4e-23 81.1 0.0 1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Gemini_V1 PF01524.12 OAP57741.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Geminivirus V1 protein MFS_1 PF07690.11 OAP57742.1 - 3.7e-19 68.6 39.4 3.7e-19 68.6 27.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily HSCB_C PF07743.8 OAP57746.1 - 1.3e-12 48.0 6.1 2.3e-12 47.2 4.2 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 OAP57746.1 - 2.1e-09 36.9 0.0 5.2e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Phage_Mu_Gam PF07352.7 OAP57746.1 - 0.4 10.1 3.1 0.64 9.5 2.1 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Med25_VWA PF11265.3 OAP57747.1 - 0.12 11.3 1.7 0.21 10.5 1.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A PAH PF02671.16 OAP57748.1 - 1.7e-47 158.7 0.3 1.4e-16 59.7 0.4 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 OAP57748.1 - 4.2e-39 132.3 0.0 1.2e-38 130.9 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Sporozoite_P67 PF05642.6 OAP57748.1 - 1.5 6.6 7.1 0.32 8.8 0.3 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Ank_2 PF12796.2 OAP57751.1 - 1.5e-35 121.3 0.4 6.3e-11 42.4 0.1 5.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP57751.1 - 2.8e-32 110.5 0.6 2e-10 40.8 0.1 6.1 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP57751.1 - 4.1e-28 96.7 1.9 1.8e-10 40.7 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 OAP57751.1 - 7.5e-23 79.1 10.5 0.0051 16.5 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 OAP57751.1 - 2.8e-22 76.5 2.9 0.0038 17.3 0.0 8.5 8 0 0 8 8 8 4 Ankyrin repeat NACHT PF05729.7 OAP57751.1 - 1.5e-08 34.5 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 OAP57751.1 - 5.1e-07 29.6 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 OAP57751.1 - 1.9e-06 28.0 0.0 0.00041 20.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP57751.1 - 0.00015 21.7 0.1 0.00086 19.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 OAP57751.1 - 0.015 14.1 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 OAP57751.1 - 0.022 13.7 0.9 0.14 11.1 0.2 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.1 OAP57751.1 - 0.066 13.1 0.0 0.33 10.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAP57751.1 - 0.073 12.8 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Shigella_OspC PF06128.6 OAP57751.1 - 0.096 12.1 0.0 1.6 8.1 0.0 2.5 2 1 0 2 2 2 0 Shigella flexneri OspC protein AAA PF00004.24 OAP57751.1 - 0.13 12.4 0.0 1.6 8.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.19 OAP57753.1 - 1.7e-62 211.4 20.5 2.1e-62 211.2 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57753.1 - 2.1e-16 59.6 32.4 2.1e-16 59.6 22.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Asp PF00026.18 OAP57755.1 - 1.2e-08 34.5 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF331 PF03889.8 OAP57755.1 - 0.008 15.4 0.6 0.74 9.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function Romo1 PF10247.4 OAP57755.1 - 0.025 14.7 1.1 4.2 7.6 0.3 2.5 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 KAT11 PF08214.6 OAP57756.1 - 3.1e-77 259.9 0.0 4e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein WW PF00397.21 OAP57758.1 - 5e-08 32.6 0.8 1e-07 31.6 0.5 1.6 1 0 0 1 1 1 1 WW domain Glyco_transf_21 PF13506.1 OAP57759.1 - 1.1e-08 34.5 0.1 0.0021 17.3 0.0 3.5 3 1 0 4 4 4 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 OAP57759.1 - 9e-08 32.1 0.0 8e-07 29.0 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Fungal_trans_2 PF11951.3 OAP57760.1 - 0.013 14.1 1.0 0.022 13.3 0.7 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glycos_transf_2 PF00535.21 OAP57761.1 - 1.1e-31 109.7 0.0 1.4e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAP57761.1 - 1e-14 54.9 0.0 1.4e-14 54.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 OAP57761.1 - 7.5e-09 35.0 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAP57761.1 - 0.0073 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.1 OAP57761.1 - 0.021 14.1 0.0 0.048 13.0 0.0 1.5 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 TPR_19 PF14559.1 OAP57762.1 - 1.8e-06 28.2 0.0 0.0041 17.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAP57762.1 - 0.001 18.9 0.1 0.023 14.6 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP57762.1 - 0.0088 16.5 0.0 7.4 7.5 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAP57762.1 - 0.025 14.2 0.0 0.51 10.0 0.0 2.7 2 1 1 3 3 3 0 TPR repeat TPR_2 PF07719.12 OAP57762.1 - 0.028 14.3 0.1 0.7 9.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP57762.1 - 0.061 13.7 0.0 6.8 7.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat HlyIII PF03006.15 OAP57763.1 - 1.2e-31 109.9 6.2 1.6e-31 109.4 4.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2029 PF09594.5 OAP57763.1 - 0.052 13.0 4.6 0.11 11.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2029) SAC3_GANP PF03399.11 OAP57764.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2463 PF09591.5 OAP57764.1 - 0.071 12.6 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Vps35 PF03635.12 OAP57766.1 - 0 1024.1 0.0 0 1023.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 VTC PF09359.5 OAP57767.1 - 2.3e-88 295.9 0.4 3.5e-88 295.3 0.3 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 OAP57767.1 - 1.4e-14 54.5 15.2 4.3e-09 36.5 0.9 3.7 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 OAP57767.1 - 6.1e-09 35.9 5.1 6.1e-09 35.9 3.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) NUDIX PF00293.23 OAP57768.1 - 2.5e-16 59.5 0.0 4.8e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Zn_clus PF00172.13 OAP57770.1 - 8e-09 35.2 10.7 1.9e-08 34.1 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP57770.1 - 0.00055 18.6 0.2 0.0012 17.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Solute_trans_a PF03619.11 OAP57771.1 - 3.9e-32 111.6 12.7 6.8e-32 110.8 8.8 1.3 1 1 0 1 1 1 1 Organic solute transporter Ostalpha FixQ PF05545.6 OAP57771.1 - 0.015 14.9 8.6 0.045 13.3 0.0 3.9 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1980 PF09323.5 OAP57771.1 - 4.8 6.8 6.7 23 4.6 2.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF3975 PF13126.1 OAP57771.1 - 9 6.5 9.0 1.5 9.0 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3975) MobB PF03205.9 OAP57772.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ORC6 PF05460.8 OAP57774.1 - 0.09 11.8 3.1 0.11 11.5 2.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Myb_DNA-binding PF00249.26 OAP57774.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 OAP57774.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Mating_C PF12737.2 OAP57775.1 - 0.06 12.2 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DisA-linker PF10635.4 OAP57775.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Myb_DNA-binding PF00249.26 OAP57777.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 OAP57777.1 - 0.032 14.4 0.1 0.072 13.2 0.0 1.6 1 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FYDLN_acid PF09538.5 OAP57777.1 - 0.65 10.6 11.3 1.1 9.8 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Cofilin_ADF PF00241.15 OAP57778.1 - 7.9e-30 103.3 0.0 8.9e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoVR PF04293.8 OAP57778.1 - 0.12 10.7 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein COX4 PF02936.9 OAP57779.1 - 4.4e-50 169.1 0.9 5e-50 168.9 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 OAP57779.1 - 0.094 12.8 0.1 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) ATP-synt_ab PF00006.20 OAP57780.1 - 1.8e-61 207.3 0.1 5.8e-61 205.7 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAP57780.1 - 1.1e-24 87.0 0.6 2.3e-24 86.0 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAP57780.1 - 9.4e-24 83.4 0.9 6.5e-23 80.7 0.3 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 OAP57780.1 - 0.0069 15.8 0.1 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAP57780.1 - 0.0071 16.5 0.1 0.64 10.2 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 OAP57780.1 - 0.01 15.5 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 OAP57780.1 - 0.014 14.5 0.1 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAP57780.1 - 0.022 14.7 1.4 0.29 11.0 0.4 2.7 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 OAP57780.1 - 0.022 14.4 0.1 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 OAP57780.1 - 0.025 14.2 0.2 1.1 8.9 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 OAP57780.1 - 0.027 13.5 0.2 0.045 12.8 0.1 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 OAP57780.1 - 0.061 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 OAP57780.1 - 0.1 12.7 0.1 0.41 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 OAP57780.1 - 0.12 11.2 0.6 0.62 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain HRDC PF00570.18 OAP57781.1 - 0.023 14.4 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 HRDC domain NPR3 PF03666.8 OAP57781.1 - 0.28 9.6 1.1 0.4 9.1 0.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AA_permease_2 PF13520.1 OAP57782.1 - 1.9e-61 207.9 49.8 2.4e-61 207.5 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP57782.1 - 1.9e-28 99.0 40.3 2.5e-28 98.6 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease SGL PF08450.7 OAP57783.1 - 0.071 12.4 0.2 1.7 7.9 0.0 2.6 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Cpn60_TCP1 PF00118.19 OAP57784.1 - 1.5e-115 386.6 9.7 1.7e-115 386.4 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HAP1_N PF04849.8 OAP57784.1 - 0.094 11.6 0.1 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1547 PF07577.6 OAP57784.1 - 1.4 8.6 4.3 0.83 9.3 0.4 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) Alpha-amylase_C PF02806.13 OAP57788.1 - 3.7e-25 87.8 0.1 8.8e-25 86.6 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 OAP57788.1 - 1.5e-17 63.4 0.0 3.9e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.19 OAP57788.1 - 2e-17 63.5 0.1 1.3e-13 51.0 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Abhydrolase_5 PF12695.2 OAP57789.1 - 2.5e-12 46.7 0.1 3.3e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP57789.1 - 5.7e-07 29.6 0.2 1.8e-05 24.7 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP57789.1 - 4.3e-05 22.8 0.0 0.025 13.8 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAP57789.1 - 0.0007 19.2 0.0 0.0018 17.8 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.6 OAP57789.1 - 0.0039 16.3 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) VirJ PF06057.6 OAP57789.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DLH PF01738.13 OAP57789.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family AAA_2 PF07724.9 OAP57790.1 - 1.2e-37 129.4 0.0 1.2e-36 126.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 OAP57790.1 - 1.5e-14 54.3 0.0 3.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 OAP57790.1 - 4.5e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 OAP57790.1 - 1.4e-06 28.0 0.0 3.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAP57790.1 - 9.5e-05 21.6 0.1 0.0079 15.3 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 OAP57790.1 - 0.0005 20.2 0.2 0.007 16.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 OAP57790.1 - 0.00083 18.8 0.0 0.082 12.3 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 OAP57790.1 - 0.00086 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 OAP57790.1 - 0.00094 19.9 0.5 0.0028 18.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP57790.1 - 0.0021 18.0 1.2 0.0037 17.2 0.1 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_24 PF13479.1 OAP57790.1 - 0.0034 16.9 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAP57790.1 - 0.012 14.7 0.3 0.14 11.2 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 OAP57790.1 - 0.027 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 OAP57790.1 - 0.027 14.3 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAP57790.1 - 0.046 13.8 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 OAP57790.1 - 0.061 13.1 0.7 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 OAP57790.1 - 0.069 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.18 OAP57790.1 - 0.077 11.7 0.1 0.23 10.2 0.1 1.6 1 1 0 1 1 1 0 MCM2/3/5 family AAA_18 PF13238.1 OAP57790.1 - 0.21 11.8 1.1 0.48 10.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain NAD_binding_10 PF13460.1 OAP57791.1 - 6.6e-12 45.8 0.1 1.2e-11 44.9 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP57791.1 - 0.0002 20.8 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GST_N_3 PF13417.1 OAP57792.1 - 2e-26 92.0 0.1 5.7e-26 90.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP57792.1 - 1.6e-17 63.2 0.1 7.8e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP57792.1 - 5.4e-10 39.2 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP57792.1 - 7.8e-07 28.9 0.1 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAP57792.1 - 0.00085 19.2 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP57792.1 - 0.0023 18.3 0.1 0.0078 16.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 OAP57792.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin APC10 PF03256.11 OAP57793.1 - 3.6e-37 127.8 0.0 2.1e-36 125.3 0.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Cas1_AcylT PF07779.7 OAP57794.1 - 2.4e-92 309.9 16.4 6e-92 308.6 11.3 1.6 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p MFS_1 PF07690.11 OAP57795.1 - 4.5e-32 111.1 74.7 7.8e-24 84.0 32.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF443 PF04276.7 OAP57795.1 - 0.037 13.4 0.4 0.081 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF443) His_Phos_1 PF00300.17 OAP57796.1 - 5.8e-19 68.7 0.1 8.2e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 OAP57796.1 - 0.025 13.9 0.1 0.057 12.7 0.0 1.5 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) PP2C PF00481.16 OAP57797.1 - 1.2e-37 129.7 0.0 1.2e-30 106.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 OAP57797.1 - 0.00022 20.7 0.1 0.0011 18.4 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C CDP-OH_P_transf PF01066.16 OAP57798.1 - 7.5e-17 61.4 6.9 7.5e-17 61.4 4.8 1.8 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Abhydrolase_3 PF07859.8 OAP57799.1 - 4.6e-42 143.9 0.0 6.2e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP57799.1 - 0.00014 20.7 0.1 0.00059 18.6 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family WD40 PF00400.27 OAP57800.1 - 5.3e-14 51.4 9.5 0.00012 21.8 0.0 6.2 8 0 0 8 8 8 3 WD domain, G-beta repeat DUF3639 PF12341.3 OAP57800.1 - 1.3e-06 28.2 0.9 1.3e-06 28.2 0.6 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 OAP57800.1 - 5.1e-05 22.2 0.0 0.00016 20.6 0.0 1.7 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 OAP57800.1 - 0.00033 20.4 0.1 0.031 14.0 0.3 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 OAP57800.1 - 0.059 12.8 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain IKI3 PF04762.7 OAP57800.1 - 0.09 10.5 0.0 0.14 9.9 0.0 1.3 1 0 0 1 1 1 0 IKI3 family PD40 PF07676.7 OAP57800.1 - 0.11 12.1 0.1 73 3.1 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DNA_pol_alpha_N PF12254.3 OAP57800.1 - 0.11 12.2 0.8 0.25 11.1 0.6 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal VID27 PF08553.5 OAP57800.1 - 0.18 9.9 0.0 0.32 9.1 0.0 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein OTT_1508_deam PF14441.1 OAP57801.1 - 2.8e-08 33.6 0.2 7.2e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF1275 PF06912.6 OAP57802.1 - 1.5e-35 122.2 12.2 1.9e-35 121.9 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) COesterase PF00135.23 OAP57803.1 - 1.9e-81 274.3 0.1 2.2e-81 274.2 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP57803.1 - 3e-09 36.7 0.2 2.6e-08 33.7 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP57803.1 - 0.0092 15.2 0.2 0.017 14.3 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP57803.1 - 0.12 12.1 1.0 0.35 10.6 0.6 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 OAP57803.1 - 0.14 10.7 0.0 8.9 4.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Fungal_trans PF04082.13 OAP57804.1 - 1.9e-16 59.7 1.6 2.9e-16 59.1 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57804.1 - 6.5e-09 35.5 7.1 1.3e-08 34.5 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Apolipoprotein PF01442.13 OAP57805.1 - 0.086 12.3 6.7 0.11 12.0 4.6 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Dapper PF15268.1 OAP57805.1 - 0.43 9.3 4.6 0.49 9.1 3.2 1.0 1 0 0 1 1 1 0 Dapper Nop53 PF07767.6 OAP57805.1 - 1.4 7.8 9.5 1.8 7.4 6.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MFS_1 PF07690.11 OAP57806.1 - 2.4e-37 128.5 23.4 2.4e-37 128.5 16.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP57806.1 - 1.2e-08 34.0 3.9 1.2e-08 34.0 2.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.14 OAP57806.1 - 5e-05 22.0 1.1 5e-05 22.0 0.7 2.1 1 1 0 2 2 2 1 LacY proton/sugar symporter Peptidase_M19 PF01244.16 OAP57807.1 - 6.2e-94 314.5 0.0 8.2e-94 314.1 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Fructosamin_kin PF03881.9 OAP57807.1 - 4.5e-73 245.7 0.0 9.9e-73 244.6 0.0 1.5 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 OAP57807.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 OAP57807.1 - 0.018 13.6 0.0 0.028 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) UFD1 PF03152.9 OAP57808.1 - 5.5e-74 247.0 0.0 6.9e-74 246.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 OAP57808.1 - 0.026 14.1 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 GYF PF02213.11 OAP57809.1 - 8.6e-12 44.4 0.3 1.7e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 GYF domain gp12-short_mid PF09089.5 OAP57809.1 - 0.064 13.2 0.6 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Phage short tail fibre protein gp12, middle domain dCMP_cyt_deam_1 PF00383.17 OAP57810.1 - 1.5e-07 30.9 3.1 1.5e-06 27.7 2.2 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF202 PF02656.10 OAP57811.1 - 0.0076 16.4 7.8 0.052 13.7 5.4 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF202) RseC_MucC PF04246.7 OAP57811.1 - 0.026 14.1 0.8 0.029 13.9 0.0 1.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Fungal_trans PF04082.13 OAP57812.1 - 5e-13 48.5 1.6 7.7e-13 47.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 OAP57812.1 - 2.4e-07 30.7 13.7 3.7e-07 30.0 1.3 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP57812.1 - 5.6e-06 26.3 10.4 0.0045 17.2 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP57812.1 - 1.9e-05 24.6 12.5 0.01 16.1 2.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 OAP57812.1 - 0.0068 16.4 3.3 0.0073 16.4 0.1 2.3 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 OAP57812.1 - 0.013 15.5 1.8 2.4 8.3 0.2 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 OAP57812.1 - 1.1 9.4 4.6 1.5 9.0 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAP57812.1 - 6.1 6.8 7.6 0.72 9.8 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger TRI12 PF06609.8 OAP57813.1 - 7e-49 166.5 26.9 9.4e-49 166.1 18.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP57813.1 - 8.3e-23 80.6 50.0 5.6e-22 77.9 31.7 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP57813.1 - 4.3e-13 48.6 10.2 4.3e-13 48.6 7.1 3.2 2 1 2 4 4 4 1 Sugar (and other) transporter TIP49 PF06068.8 OAP57814.1 - 1.5e-172 573.7 4.0 1.8e-172 573.5 2.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 OAP57814.1 - 4.7e-09 36.5 1.0 4.4e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAP57814.1 - 1.6e-07 30.6 2.5 5.7e-05 22.2 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAP57814.1 - 8e-05 22.7 0.0 0.00038 20.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAP57814.1 - 0.00017 21.7 0.0 0.4 10.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain DnaB_C PF03796.10 OAP57814.1 - 0.00018 20.4 0.3 0.0003 19.7 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 OAP57814.1 - 0.0028 16.8 0.8 0.026 13.6 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 OAP57814.1 - 0.0047 16.8 0.0 4.3 7.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 OAP57814.1 - 0.0096 15.4 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 OAP57814.1 - 0.01 15.2 0.1 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 OAP57814.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 OAP57814.1 - 0.011 15.4 0.7 0.04 13.6 0.2 2.1 1 1 1 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 OAP57814.1 - 0.015 14.9 0.0 0.28 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_32 PF13654.1 OAP57814.1 - 0.019 13.6 0.0 0.037 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAP57814.1 - 0.057 12.8 0.7 0.15 11.5 0.0 1.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 OAP57814.1 - 0.07 12.2 0.2 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 OAP57814.1 - 0.088 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 OAP57814.1 - 0.11 12.3 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain FlaC_arch PF05377.6 OAP57815.1 - 0.013 15.3 9.7 0.69 9.8 0.1 4.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Peptidase_S49 PF01343.13 OAP57815.1 - 0.13 12.0 3.2 0.35 10.6 2.2 1.8 1 0 0 1 1 1 0 Peptidase family S49 V_ATPase_I PF01496.14 OAP57815.1 - 0.44 8.3 19.2 0.77 7.5 13.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 OAP57815.1 - 0.64 9.8 6.6 0.42 10.4 0.8 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PhyH PF05721.8 OAP57816.1 - 1.2e-27 97.3 0.0 1.6e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 OAP57816.1 - 0.15 10.5 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) zf-A20 PF01754.11 OAP57818.1 - 0.57 9.8 0.1 0.98 9.0 0.1 1.4 1 0 0 1 1 1 0 A20-like zinc finger DUF445 PF04286.7 OAP57818.1 - 0.6 9.5 10.6 0.052 13.0 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Chs3p PF12271.3 OAP57819.1 - 6.4e-101 337.1 10.3 7.2e-101 337.0 7.1 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit YvrJ PF12841.2 OAP57819.1 - 0.033 13.4 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family V1R PF03402.9 OAP57819.1 - 2.4 7.4 6.9 0.28 10.5 0.9 2.3 3 1 0 3 3 3 0 Vomeronasal organ pheromone receptor family, V1R HET PF06985.6 OAP57820.1 - 1.6e-25 89.8 0.3 2.9e-25 89.0 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OTCace PF00185.19 OAP57820.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LRR_4 PF12799.2 OAP57821.1 - 0.022 14.3 5.6 3.9 7.1 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF1669 PF07894.7 OAP57821.1 - 3 6.9 5.7 2.2 7.4 2.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1669) Pyr_redox_3 PF13738.1 OAP57822.1 - 9.5e-29 100.9 0.0 1.9e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP57822.1 - 9.8e-16 57.0 0.2 4.2e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP57822.1 - 2.1e-10 40.8 0.0 5.1e-05 23.2 0.0 3.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP57822.1 - 3.1e-09 36.2 0.1 1.1e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP57822.1 - 5.6e-06 26.2 0.0 2.7e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP57822.1 - 6e-05 22.8 1.6 0.025 14.3 0.6 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 OAP57822.1 - 0.024 14.8 0.0 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 OAP57822.1 - 0.026 14.9 0.1 8.6 6.8 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP57822.1 - 0.028 13.3 3.7 5.6 5.7 0.0 3.4 2 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP57822.1 - 0.052 12.4 0.1 0.4 9.4 0.0 2.3 2 1 1 3 3 3 0 FAD binding domain DUF1902 PF08972.6 OAP57822.1 - 0.11 12.0 2.2 0.24 11.0 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Lycopene_cycl PF05834.7 OAP57822.1 - 0.16 10.8 0.9 0.61 8.9 0.2 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein Peptidase_M16 PF00675.15 OAP57823.1 - 4.9e-16 58.8 0.0 9.4e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAP57823.1 - 2.4e-13 50.1 0.0 4.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain TFIIE_alpha PF02002.12 OAP57824.1 - 0.00015 21.2 0.6 0.00074 18.9 0.1 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit RNA_pol_Rpc82 PF05645.8 OAP57824.1 - 0.00038 20.0 0.0 0.066 12.7 0.0 3.6 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 DUF1131 PF06572.7 OAP57824.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) ATP-synt_Eps PF04627.8 OAP57825.1 - 1.4e-22 78.9 0.6 1.8e-22 78.5 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 OAP57826.1 - 9.4e-47 158.3 0.0 1.6e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Brix PF04427.13 OAP57827.1 - 3e-31 108.5 0.0 4.1e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain Aldo_ket_red PF00248.16 OAP57828.1 - 1.9e-50 171.2 0.0 2.2e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 OAP57830.1 - 8.1e-06 25.4 0.3 4.2e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAP57830.1 - 0.026 14.1 0.1 0.069 12.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain Pyr_redox_3 PF13738.1 OAP57831.1 - 1.9e-21 77.0 0.0 4.4e-20 72.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP57831.1 - 2.6e-09 35.8 0.0 7.7e-06 24.3 0.0 2.8 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP57831.1 - 1.5e-05 25.0 0.0 0.00013 21.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP57831.1 - 1.5e-05 24.9 1.1 3.1e-05 23.8 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 OAP57831.1 - 0.035 14.2 0.4 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3060 PF11259.3 OAP57831.1 - 0.05 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) DAO PF01266.19 OAP57831.1 - 0.12 11.2 2.4 4.5 6.0 0.9 3.0 2 1 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 OAP57831.1 - 0.76 8.8 2.6 0.89 8.5 0.6 1.8 2 0 0 2 2 2 0 Thi4 family Aldolase_II PF00596.16 OAP57832.1 - 2.3e-47 161.0 0.0 3e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ADH_N PF08240.7 OAP57833.1 - 2.8e-26 91.3 1.5 6.2e-26 90.3 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP57833.1 - 1.4e-19 69.9 0.0 2.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 OAP57833.1 - 0.001 19.1 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAP57833.1 - 0.0012 18.8 0.1 0.0019 18.1 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.14 OAP57833.1 - 0.0064 15.5 0.3 0.011 14.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain F420_oxidored PF03807.12 OAP57833.1 - 0.043 14.2 0.1 0.077 13.4 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 OAP57833.1 - 0.05 13.7 0.1 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 OAP57833.1 - 0.11 12.8 0.1 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 OAP57833.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.13 OAP57834.1 - 2.6e-20 72.3 0.0 4.3e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP57834.1 - 1.1e-06 28.4 8.2 2e-06 27.6 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 OAP57835.1 - 9e-26 91.1 0.0 1.4e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP57835.1 - 4.4e-14 51.5 0.0 2.1e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP57835.1 - 2.4e-07 30.6 0.0 8.2e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP57835.1 - 4.9e-06 25.6 0.0 5.1e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP57835.1 - 6.1e-05 22.9 0.0 0.057 13.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP57835.1 - 0.00072 18.5 1.0 0.23 10.3 0.1 3.0 1 1 2 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP57835.1 - 0.0051 17.1 0.2 1.8 9.0 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP57835.1 - 0.0094 15.0 0.4 0.059 12.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 OAP57835.1 - 0.017 14.9 0.3 0.44 10.3 0.0 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 OAP57835.1 - 0.019 15.0 0.3 0.66 10.0 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 OAP57835.1 - 0.02 13.8 0.1 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 OAP57835.1 - 0.026 13.6 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP57835.1 - 0.064 13.5 0.0 15 5.8 0.0 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 OAP57835.1 - 0.093 11.5 0.0 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Sugar_tr PF00083.19 OAP57836.1 - 1.1e-89 301.1 27.5 1.3e-89 300.8 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57836.1 - 1e-21 77.0 20.7 1e-21 77.0 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 OAP57837.1 - 6.1e-134 446.8 0.0 7.8e-134 446.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP57837.1 - 6.4e-05 21.8 0.0 0.0009 18.0 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Ras PF00071.17 OAP57838.1 - 2.8e-63 212.1 0.3 3.3e-63 211.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP57838.1 - 2.2e-21 76.5 0.1 3.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP57838.1 - 2.3e-13 49.7 0.1 3.1e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAP57838.1 - 3.6e-08 33.3 0.0 5.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAP57838.1 - 1.6e-05 24.4 0.1 5.1e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAP57838.1 - 8.3e-05 21.8 0.2 0.00014 21.0 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 OAP57838.1 - 0.00016 21.8 0.1 0.00045 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAP57838.1 - 0.0015 18.4 0.1 0.0044 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 OAP57838.1 - 0.002 17.2 0.1 0.0026 16.8 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 OAP57838.1 - 0.0025 17.0 0.1 0.0057 15.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 OAP57838.1 - 0.0094 15.8 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 OAP57838.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 OAP57838.1 - 0.018 14.6 0.1 0.036 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 OAP57838.1 - 0.019 15.2 0.1 0.027 14.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 OAP57838.1 - 0.022 14.7 0.2 0.046 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 OAP57838.1 - 0.072 12.3 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 OAP57838.1 - 0.095 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 OAP57838.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 OAP57839.1 - 2.4e-08 33.5 0.0 5.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cyclin PF08613.6 OAP57840.1 - 5.3e-29 101.5 0.0 9.9e-29 100.6 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAP57840.1 - 1.1e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PAT1 PF09770.4 OAP57840.1 - 8.6 4.4 9.9 11 4.1 6.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HEAT_2 PF13646.1 OAP57841.1 - 3.8e-08 33.5 6.5 6.7e-06 26.3 0.6 5.5 4 1 1 5 5 5 1 HEAT repeats Arm PF00514.18 OAP57841.1 - 5e-05 22.9 17.7 0.02 14.6 0.0 7.5 10 1 0 10 10 10 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 OAP57841.1 - 0.0019 18.1 13.0 0.065 13.3 0.0 6.5 6 0 0 6 6 6 1 HEAT repeat U3snoRNP10 PF12397.3 OAP57841.1 - 0.013 15.4 2.1 0.21 11.5 0.1 3.0 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 SR-25 PF10500.4 OAP57842.1 - 2.7 7.3 15.5 4.3 6.7 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4603 PF15376.1 OAP57842.1 - 2.7 5.0 6.0 3.7 4.5 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CBFD_NFYB_HMF PF00808.18 OAP57843.1 - 1.6e-05 24.8 0.1 2e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAP57843.1 - 0.0091 16.0 0.3 0.012 15.6 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Med17 PF10156.4 OAP57843.1 - 0.12 10.5 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Vip3A_N PF12495.3 OAP57844.1 - 0.014 15.1 0.4 0.024 14.3 0.3 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal APP_E2 PF12925.2 OAP57844.1 - 0.082 12.4 9.0 0.11 12.1 5.7 1.6 1 1 0 1 1 1 0 E2 domain of amyloid precursor protein TMF_TATA_bd PF12325.3 OAP57844.1 - 0.14 11.8 7.8 0.037 13.7 1.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 OAP57844.1 - 2.8 6.8 9.7 5 5.9 6.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PQQ_3 PF13570.1 OAP57845.1 - 0.038 14.2 0.3 5.1 7.4 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain Pex16 PF08610.5 OAP57847.1 - 3.4e-98 328.7 0.4 4.2e-98 328.4 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) ASXH PF13919.1 OAP57848.1 - 3.5e-12 46.2 0.0 4.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Asx homology domain Myb_DNA-binding PF00249.26 OAP57849.1 - 1.3e-12 47.5 1.2 1.1e-10 41.4 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAP57849.1 - 1.4e-10 41.1 0.4 2e-07 30.9 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.7 OAP57850.1 - 4.4e-13 49.5 0.0 7.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP57850.1 - 2e-09 37.3 0.0 1.9e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP57850.1 - 8.5e-08 31.9 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP57850.1 - 4.6e-07 30.1 0.0 8.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP57850.1 - 2.5e-05 24.6 0.0 5.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP57850.1 - 4.8e-05 23.9 0.1 9.4e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 OAP57850.1 - 0.0052 15.5 0.1 0.019 13.7 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.7 OAP57850.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TIG PF01833.19 OAP57851.1 - 2.4e-13 49.8 0.4 1.9e-12 47.0 0.1 2.6 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 OAP57851.1 - 1.3e-10 41.5 0.1 2.4e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAP57851.1 - 2.8e-09 36.3 6.1 0.00022 20.8 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 OAP57851.1 - 5.7e-09 35.3 1.4 0.0048 17.0 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 OAP57851.1 - 7e-08 32.7 0.8 1.5e-07 31.7 0.5 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP57851.1 - 4.3e-07 29.9 5.9 6.2e-05 23.1 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) adh_short PF00106.20 OAP57852.1 - 3e-19 69.5 0.3 7.1e-19 68.3 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57852.1 - 2.9e-11 43.6 0.0 4.5e-11 42.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP57852.1 - 4.1e-07 29.8 0.5 4e-05 23.3 0.0 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 OAP57852.1 - 2.2e-06 27.3 0.0 4.1e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP57852.1 - 8.8e-05 22.5 0.1 0.00043 20.3 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP57852.1 - 0.00015 20.6 0.0 0.00027 19.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAP57852.1 - 0.016 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 OAP57852.1 - 0.023 13.9 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DUF1295 PF06966.7 OAP57853.1 - 3.6e-13 49.3 0.2 4.5e-13 49.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 OAP57853.1 - 3.4e-06 26.9 0.1 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 OAP57853.1 - 4.5e-05 23.5 0.5 0.00013 22.0 0.2 1.9 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 OAP57853.1 - 0.00038 19.1 1.2 0.00061 18.4 0.4 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 OAP57853.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF3357 PF11837.3 OAP57854.1 - 0.02 14.7 0.2 0.62 9.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Cytochrom_B561 PF03188.11 OAP57854.1 - 0.069 12.9 6.0 0.071 12.9 2.4 2.3 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 OMP_b-brl PF13505.1 OAP57854.1 - 0.15 11.9 3.8 0.51 10.2 2.0 2.0 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain zf-CCHC PF00098.18 OAP57855.1 - 2.1e-34 115.7 40.8 2e-08 33.7 0.6 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 OAP57855.1 - 1.2e-05 24.8 30.8 0.3 10.7 1.0 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 OAP57855.1 - 0.0011 18.6 28.6 0.051 13.3 0.5 4.9 3 1 2 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAP57855.1 - 0.0011 18.3 21.4 0.0023 17.3 1.7 4.4 2 1 2 4 4 4 2 Zinc knuckle zf-CCHC_6 PF15288.1 OAP57855.1 - 0.0083 15.7 31.4 0.32 10.7 0.1 5.3 4 1 1 5 5 5 3 Zinc knuckle zf-CCHC_5 PF14787.1 OAP57855.1 - 4.8 6.7 24.5 1.3 8.5 1.0 4.3 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger F-box-like PF12937.2 OAP57856.1 - 3.9e-08 32.8 0.1 7.8e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP57856.1 - 4.2e-08 32.6 1.7 8.1e-08 31.7 1.2 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 OAP57856.1 - 0.06 12.8 0.1 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain SAE2 PF08573.5 OAP57857.1 - 4.7e-21 75.2 0.0 4.7e-21 75.2 0.0 3.0 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HALZ PF02183.13 OAP57857.1 - 0.021 14.5 0.6 0.021 14.5 0.4 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Gag_p24 PF00607.15 OAP57857.1 - 0.052 13.0 3.7 4 6.9 0.7 2.1 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) Viral_P18 PF04521.8 OAP57857.1 - 0.15 11.5 6.7 0.37 10.2 1.3 3.1 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Spc7 PF08317.6 OAP57857.1 - 0.17 10.5 7.9 0.33 9.5 5.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF342 PF03961.8 OAP57857.1 - 0.34 9.2 4.1 0.54 8.6 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FUSC PF04632.7 OAP57857.1 - 0.59 8.5 6.3 0.82 8.0 4.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vps51 PF08700.6 OAP57857.1 - 0.78 9.6 4.9 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 Vps51/Vps67 PHZA_PHZB PF03284.8 OAP57858.1 - 0.17 10.9 0.9 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B AMP-binding PF00501.23 OAP57860.1 - 4.2e-75 252.7 0.0 5.5e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP57860.1 - 3.1e-09 37.6 0.0 8.8e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UPF0180 PF03698.8 OAP57860.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) CAP_GLY PF01302.20 OAP57861.1 - 1.7e-17 62.8 3.0 1e-12 47.5 1.0 2.2 1 1 1 2 2 2 2 CAP-Gly domain Ubiquitin_2 PF14560.1 OAP57861.1 - 2.7e-14 53.1 0.0 6.3e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 OAP57861.1 - 0.00016 21.0 0.0 0.00036 19.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family PB1 PF00564.19 OAP57861.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 PB1 domain CENP-C_C PF11699.3 OAP57862.1 - 3.5e-29 100.6 0.1 7.3e-29 99.5 0.1 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 OAP57862.1 - 4.2e-25 88.9 2.8 4.2e-25 88.9 1.9 3.2 3 2 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 OAP57862.1 - 7.7e-06 25.3 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 OAP57862.1 - 0.029 13.7 0.1 0.072 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RNase_HII PF01351.13 OAP57863.1 - 1.2e-46 158.8 0.0 1.8e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease HII PBC PF03792.8 OAP57863.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 PBC domain FMN_dh PF01070.13 OAP57864.1 - 1.3e-100 336.7 0.0 1.7e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAP57864.1 - 5.2e-19 67.8 0.0 1.7e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAP57864.1 - 8.1e-08 31.5 0.2 1.2e-07 31.0 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAP57864.1 - 9.1e-07 28.0 0.1 5.1e-05 22.3 0.1 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 OAP57864.1 - 0.011 14.9 0.3 0.021 13.9 0.2 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 OAP57864.1 - 0.024 13.6 0.1 0.039 12.9 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 OAP57864.1 - 0.03 13.5 0.0 0.077 12.2 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.9 OAP57864.1 - 0.099 11.6 0.2 0.23 10.4 0.0 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG ATP11 PF06644.6 OAP57864.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein p450 PF00067.17 OAP57865.1 - 3e-52 177.6 0.0 3.9e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 OAP57866.1 - 2.9e-45 154.4 65.4 3.6e-39 134.4 36.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP57866.1 - 1.1e-07 30.7 9.7 1.1e-07 30.7 6.7 2.7 1 1 0 2 2 2 2 Sugar (and other) transporter Cauli_VI PF01693.11 OAP57867.1 - 9.8e-34 115.1 4.0 6.8e-16 58.0 0.5 2.8 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 OAP57867.1 - 5.2e-25 88.3 0.2 4.3e-21 75.6 0.1 2.5 2 0 0 2 2 2 2 RNase H Na_H_Exchanger PF00999.16 OAP57868.1 - 1.5e-41 142.2 16.1 2e-41 141.8 11.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1049 PF06305.6 OAP57868.1 - 0.5 9.8 2.9 30 4.2 0.0 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) MARVEL PF01284.18 OAP57868.1 - 9.7 6.0 14.3 2.7 7.8 1.9 3.6 3 1 0 3 3 3 0 Membrane-associating domain 6PF2K PF01591.13 OAP57869.1 - 4.1e-67 225.5 0.8 1.2e-47 161.9 0.3 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 OAP57869.1 - 7e-26 91.2 0.1 2.3e-25 89.5 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 OAP57869.1 - 3.7e-08 33.3 0.2 0.00056 19.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAP57869.1 - 0.0031 18.3 0.0 0.015 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 OAP57869.1 - 0.017 14.3 0.0 0.57 9.3 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 WLM PF08325.5 OAP57870.1 - 1.3e-43 149.0 0.0 2e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 OAP57870.1 - 0.0078 16.0 0.5 0.028 14.2 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 Peptidase_MA_2 PF13485.1 OAP57870.1 - 0.027 14.4 0.1 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Cu_amine_oxid PF01179.15 OAP57871.1 - 2.3e-162 540.4 0.0 2.8e-162 540.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 OAP57871.1 - 6.2e-07 29.4 1.2 1.2e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 OAP57871.1 - 4.2e-06 26.7 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Rad51 PF08423.6 OAP57872.1 - 1.9e-23 82.6 0.0 2.9e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 OAP57872.1 - 5.4e-10 39.0 0.1 9.7e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 OAP57872.1 - 0.00011 21.3 0.0 0.00026 20.1 0.0 1.6 1 1 0 1 1 1 1 KaiC RecA PF00154.16 OAP57872.1 - 0.0063 15.6 0.1 0.17 10.8 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 OAP57872.1 - 0.022 13.6 0.0 3.6 6.3 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RSS_P20 PF11757.3 OAP57872.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like Peptidase_S9 PF00326.16 OAP57873.1 - 6.4e-46 156.2 0.0 9.2e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP57873.1 - 9.8e-13 48.0 0.1 2.2e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 OAP57873.1 - 5.9e-11 42.0 0.5 9.2e-08 31.6 0.0 2.5 3 0 0 3 3 3 2 Dienelactone hydrolase family Peptidase_S15 PF02129.13 OAP57873.1 - 1.2e-09 37.9 0.0 4.8e-06 26.2 0.1 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 OAP57873.1 - 1.5e-09 38.0 0.4 4.6e-09 36.4 0.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAP57873.1 - 1e-06 28.6 0.1 1.6e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PD40 PF07676.7 OAP57873.1 - 6.5e-06 25.6 0.3 0.092 12.4 0.0 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.8 OAP57873.1 - 8.3e-06 25.5 0.1 3.3e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 OAP57873.1 - 8.4e-06 25.5 0.5 0.12 11.8 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 OAP57873.1 - 0.00015 20.3 0.0 0.00038 19.0 0.0 1.6 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) LIP PF03583.9 OAP57873.1 - 0.00047 19.4 2.9 0.29 10.2 1.8 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_2 PF02230.11 OAP57873.1 - 0.0013 18.2 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.15 OAP57873.1 - 0.017 14.5 0.6 0.054 12.9 0.4 1.7 1 1 0 1 1 1 0 Putative esterase DNA_ligase_OB_2 PF14743.1 OAP57873.1 - 0.019 14.6 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 DNA ligase OB-like domain COesterase PF00135.23 OAP57873.1 - 0.028 13.1 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family DPPIV_N PF00930.16 OAP57873.1 - 0.036 12.6 0.1 0.11 11.0 0.0 1.7 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1749 PF08538.5 OAP57873.1 - 0.036 12.9 0.1 0.19 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Esterase_phd PF10503.4 OAP57873.1 - 0.054 12.7 4.3 0.26 10.5 3.0 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase PAE PF03283.8 OAP57873.1 - 0.059 11.9 0.1 0.21 10.1 0.0 1.8 2 0 0 2 2 2 0 Pectinacetylesterase FSH1 PF03959.8 OAP57873.1 - 0.077 12.4 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2305 PF10230.4 OAP57873.1 - 0.085 12.2 0.0 0.61 9.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF2665 PF11654.3 OAP57874.1 - 8.1e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) GFA PF04828.9 OAP57875.1 - 3.6e-22 78.1 0.2 4.6e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.3 OAP57875.1 - 0.78 9.9 6.9 6 7.1 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) Mito_carr PF00153.22 OAP57876.1 - 4.7e-33 112.7 5.4 2.8e-15 55.8 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CTD_bind PF04818.8 OAP57877.1 - 0.00046 20.3 0.0 0.0016 18.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.14 OAP57877.1 - 0.004 16.8 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 VHS domain zf-ISL3 PF14690.1 OAP57877.1 - 0.0053 16.7 0.7 0.013 15.4 0.5 1.6 1 0 0 1 1 1 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 CFIA_Pcf11 PF11526.3 OAP57877.1 - 0.059 13.5 0.3 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 HOOK PF05622.7 OAP57879.1 - 9.4e-26 89.8 48.7 2e-21 75.5 33.8 2.8 1 1 0 1 1 1 1 HOOK protein DUF3896 PF13035.1 OAP57879.1 - 1.1 9.3 6.9 0.22 11.5 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Lactamase_B_2 PF12706.2 OAP57881.1 - 0.00028 20.4 0.2 0.00036 20.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP57881.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAP57881.1 - 0.76 9.3 8.3 4.5 6.8 5.8 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily NAD_binding_2 PF03446.10 OAP57882.1 - 2.6e-32 111.9 1.0 4.5e-32 111.1 0.7 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP57882.1 - 2.7e-21 75.8 0.2 1.6e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 OAP57882.1 - 1.7e-06 27.0 0.2 2.7e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 OAP57882.1 - 0.0016 18.8 0.1 0.0044 17.4 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 OAP57882.1 - 0.063 12.6 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 OAP57882.1 - 0.069 12.7 0.2 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 OAP57883.1 - 2.6e-11 42.9 2.5 1.1e-10 40.9 0.4 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP57883.1 - 9.9e-08 31.8 12.9 0.0025 18.0 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP57883.1 - 1.4e-06 28.1 13.0 0.0054 16.9 4.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP57883.1 - 2.9e-06 27.2 3.4 2.9e-06 27.2 2.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain RRN7 PF11781.3 OAP57883.1 - 0.058 12.9 1.5 0.16 11.4 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 OAP57883.1 - 0.91 9.7 5.5 2.9 8.1 1.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAP57883.1 - 0.96 9.4 8.3 8.4 6.4 2.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Lactamase_B PF00753.22 OAP57884.1 - 3.5e-09 36.5 0.4 1.5e-08 34.5 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP57884.1 - 0.00018 21.1 0.2 0.00035 20.1 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CMD PF02627.15 OAP57885.1 - 1.6e-14 53.4 0.0 4.8e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 OAP57886.1 - 5.6e-39 133.8 21.7 8.1e-39 133.3 15.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Alpha-amylase PF00128.19 OAP57887.1 - 2.3e-25 89.6 0.0 5.8e-25 88.3 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 OAP57887.1 - 0.00061 17.7 0.0 0.7 7.5 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 Tannase PF07519.6 OAP57888.1 - 5.7e-102 341.8 1.9 6.7e-102 341.6 1.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 OAP57888.1 - 7.9e-05 22.6 0.7 0.00012 22.0 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP57888.1 - 0.00017 20.8 0.1 0.032 13.4 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAP57888.1 - 0.0039 16.7 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADK PF00406.17 OAP57889.1 - 1.1e-59 200.6 0.0 1.5e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 OAP57889.1 - 2.2e-14 52.8 0.0 4.6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 OAP57889.1 - 7.2e-06 26.8 0.2 1.8e-05 25.5 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAP57889.1 - 0.00021 21.1 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP57889.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Myosin_tail_1 PF01576.14 OAP57889.1 - 0.046 11.4 0.1 0.072 10.8 0.1 1.2 1 0 0 1 1 1 0 Myosin tail GFO_IDH_MocA PF01408.17 OAP57890.1 - 4.1e-15 56.3 0.0 7.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RRM_1 PF00076.17 OAP57891.1 - 8.4e-17 60.5 0.0 4.9e-13 48.5 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP57891.1 - 4e-16 58.7 0.0 1.8e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP57891.1 - 1.7e-07 30.9 0.0 0.00016 21.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N_3 PF13417.1 OAP57892.1 - 8e-15 54.8 0.0 1.5e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP57892.1 - 1.6e-12 47.4 0.0 2.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP57892.1 - 5.5e-12 45.5 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP57892.1 - 4.8e-09 36.0 0.0 7.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAP57892.1 - 1.9e-06 27.6 0.2 1e-05 25.3 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP57892.1 - 4.1e-06 27.1 0.1 7.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_11 PF08241.7 OAP57894.1 - 1.2e-16 60.9 0.0 2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP57894.1 - 1e-15 58.2 0.0 1.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP57894.1 - 1.2e-14 54.5 0.0 2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP57894.1 - 7.6e-14 51.5 0.0 1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP57894.1 - 1.3e-12 47.6 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAP57894.1 - 3.7e-11 42.6 0.0 5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 OAP57894.1 - 1.4e-08 35.0 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP57894.1 - 5.7e-08 32.8 0.2 1.3e-07 31.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP57894.1 - 1e-07 31.3 0.0 1.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAP57894.1 - 5.4e-06 25.8 0.0 1.9e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 OAP57894.1 - 7e-06 25.3 0.0 9.9e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 OAP57894.1 - 2.2e-05 24.1 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 OAP57894.1 - 0.00089 18.9 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.14 OAP57894.1 - 0.0013 18.0 0.0 0.01 15.1 0.0 1.9 1 1 1 2 2 2 1 MraW methylase family FtsJ PF01728.14 OAP57894.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 OAP57894.1 - 0.002 16.9 0.0 0.0029 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.10 OAP57894.1 - 0.0042 16.7 0.1 0.069 12.7 0.1 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.13 OAP57894.1 - 0.0081 15.3 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FmrO PF07091.6 OAP57894.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TehB PF03848.9 OAP57894.1 - 0.017 14.3 0.0 0.031 13.4 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB ADH_zinc_N PF00107.21 OAP57894.1 - 0.055 13.0 0.1 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_7 PF03492.10 OAP57894.1 - 0.082 11.6 0.0 0.96 8.1 0.0 2.1 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase Methyltransf_4 PF02390.12 OAP57894.1 - 0.11 11.5 0.0 0.52 9.3 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase CDC14 PF08045.6 OAP57895.1 - 2.4e-92 308.6 0.0 3.1e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component U3snoRNP10 PF12397.3 OAP57895.1 - 0.094 12.6 0.2 7.2 6.5 0.0 2.2 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 polyprenyl_synt PF00348.12 OAP57896.1 - 8.5e-62 208.3 0.0 1e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 OAP57897.1 - 9.1e-62 209.0 0.0 1.2e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IGPS PF00218.16 OAP57898.1 - 4.6e-97 324.0 0.0 1.4e-96 322.4 0.0 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 OAP57898.1 - 4.7e-50 169.7 0.0 9.4e-50 168.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 OAP57898.1 - 3.9e-46 157.1 0.0 1.3e-42 145.6 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 OAP57898.1 - 4.4e-06 26.2 0.1 1.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 OAP57898.1 - 1e-05 25.1 0.2 0.00047 19.7 0.0 2.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 OAP57898.1 - 0.0035 16.3 0.2 0.052 12.5 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 OAP57898.1 - 0.0093 15.2 0.1 0.27 10.4 0.0 3.1 4 0 0 4 4 4 1 Histidine biosynthesis protein AhpC-TSA_2 PF13911.1 OAP57899.1 - 1.6e-12 47.3 0.0 3.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme UPF1_Zn_bind PF09416.5 OAP57900.1 - 1.7e-73 245.2 2.6 1.7e-73 245.2 1.8 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 OAP57900.1 - 4e-60 202.6 0.0 8.5e-60 201.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 OAP57900.1 - 4.6e-58 196.5 1.0 7.8e-58 195.8 0.7 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP57900.1 - 1.1e-13 50.7 0.1 3.2e-13 49.2 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAP57900.1 - 6.3e-12 45.4 0.2 1.3e-10 41.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 OAP57900.1 - 3.3e-08 33.5 0.0 6.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 OAP57900.1 - 0.00018 21.0 0.1 0.49 9.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 OAP57900.1 - 0.00068 18.7 0.7 0.0041 16.1 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 OAP57900.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 OAP57900.1 - 0.0014 17.9 0.1 0.036 13.3 0.0 2.5 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 OAP57900.1 - 0.0018 17.2 0.1 0.46 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.24 OAP57900.1 - 0.0084 15.6 0.1 0.019 14.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 OAP57900.1 - 0.0091 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain AAA_16 PF13191.1 OAP57900.1 - 0.043 13.8 0.1 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 OAP57900.1 - 0.094 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 OAP57900.1 - 0.14 11.2 0.0 0.42 9.6 0.0 1.8 2 0 0 2 2 2 0 KaiC T2SE PF00437.15 OAP57900.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 OAP57900.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Brix PF04427.13 OAP57901.1 - 1.7e-45 155.0 0.1 2.2e-45 154.6 0.1 1.1 1 0 0 1 1 1 1 Brix domain Nup188 PF10487.4 OAP57903.1 - 8.2e-36 123.3 2.4 8.2e-36 123.3 1.7 1.9 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 AMP-binding PF00501.23 OAP57905.1 - 7.8e-82 274.8 0.0 1e-81 274.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP57905.1 - 5.3e-14 52.9 0.2 1.8e-13 51.2 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4188 PF13826.1 OAP57906.1 - 2.9e-31 107.9 0.8 4.7e-31 107.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 OAP57906.1 - 0.0004 19.5 0.8 0.00054 19.1 0.6 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase DUF3291 PF11695.3 OAP57906.1 - 0.0014 18.1 0.1 0.0019 17.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) DASH_Spc19 PF08287.6 OAP57906.1 - 0.065 12.8 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Spc19 FA_desaturase PF00487.19 OAP57907.1 - 6.7e-27 94.5 14.7 8.7e-27 94.1 10.2 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 OAP57907.1 - 2.3e-07 30.9 0.0 4.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TRAPPC10 PF12584.3 OAP57908.1 - 1e-13 51.0 0.0 6.6e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Nbs1_C PF08599.5 OAP57908.1 - 0.054 13.4 0.2 0.73 9.7 0.1 2.5 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 RVT_1 PF00078.22 OAP57909.1 - 9.8e-09 34.8 0.0 4.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L11 PF00298.14 OAP57909.1 - 0.22 11.6 0.0 0.53 10.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain SWIM PF04434.12 OAP57910.1 - 4.3e-05 22.8 1.2 0.067 12.6 0.0 2.4 2 0 0 2 2 2 2 SWIM zinc finger MitMem_reg PF13012.1 OAP57911.1 - 1.4e-40 137.9 0.2 3.5e-40 136.6 0.1 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 OAP57911.1 - 8.4e-28 96.4 0.4 2.9e-27 94.6 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2999 PF11212.3 OAP57911.1 - 0.07 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) RNase_H2-Ydr279 PF09468.5 OAP57911.1 - 0.13 11.4 5.5 0.2 10.8 3.8 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1682 PF07946.9 OAP57911.1 - 0.34 9.7 8.2 0.48 9.2 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NARP1 PF12569.3 OAP57911.1 - 1.2 7.7 9.6 1.7 7.3 6.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2201_N PF13203.1 OAP57911.1 - 4.7 6.2 7.0 4.1 6.4 4.0 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain p450 PF00067.17 OAP57912.1 - 6.4e-71 239.2 0.0 8e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ThuA PF06283.6 OAP57912.1 - 0.0025 17.5 0.6 1.2 8.7 0.0 2.6 3 0 0 3 3 3 2 Trehalose utilisation Cu-oxidase_3 PF07732.10 OAP57913.1 - 1.5e-36 124.7 2.9 1.5e-36 124.7 2.0 3.7 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP57913.1 - 1e-34 118.9 8.7 2.8e-34 117.5 0.3 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 OAP57913.1 - 1.3e-27 96.6 0.1 1.3e-27 96.6 0.1 2.8 3 1 0 3 3 3 1 Multicopper oxidase DUF1266 PF06889.6 OAP57914.1 - 0.11 12.3 2.4 2.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) FKBP_N PF01346.13 OAP57914.1 - 0.8 9.7 10.2 1 9.4 1.4 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2201_N PF13203.1 OAP57914.1 - 1.3 8.1 13.4 0.087 11.9 4.1 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF3560 PF12083.3 OAP57914.1 - 2.9 7.9 10.3 7.3 6.6 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Fungal_trans PF04082.13 OAP57915.1 - 5.9e-13 48.2 0.1 9.7e-13 47.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.8 OAP57916.1 - 4.1e-44 150.7 17.2 4.9e-44 150.5 11.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP57916.1 - 4.9e-19 68.2 52.6 8.7e-19 67.4 35.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP57916.1 - 1.9e-05 23.4 10.2 1.9e-05 23.4 7.1 3.7 3 1 1 4 4 4 3 Sugar (and other) transporter Cupin_2 PF07883.6 OAP57917.1 - 3e-08 33.0 0.1 5.1e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 OAP57917.1 - 6.9e-06 25.7 0.3 1e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 OAP57917.1 - 0.0019 17.9 0.3 0.0024 17.5 0.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 OAP57917.1 - 0.016 14.6 0.1 0.15 11.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Cupin_1 PF00190.17 OAP57917.1 - 0.049 13.0 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF2917 PF11142.3 OAP57917.1 - 0.39 9.9 3.2 0.23 10.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) Cupin_2 PF07883.6 OAP57918.1 - 0.00098 18.5 0.1 0.0041 16.5 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Ectoine_synth PF06339.7 OAP57918.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Ectoine synthase Cupin_3 PF05899.7 OAP57918.1 - 0.14 11.5 0.1 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) adh_short PF00106.20 OAP57919.1 - 1.5e-25 90.0 0.0 1.8e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57919.1 - 2.9e-16 59.9 0.0 4e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAP57919.1 - 3.4e-09 36.9 0.0 5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAP57919.1 - 2.8e-08 33.6 0.0 3.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP57919.1 - 6.2e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 OAP57919.1 - 0.0011 18.2 0.1 0.0066 15.7 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 OAP57919.1 - 0.013 15.8 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 OAP57919.1 - 0.043 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 OAP57919.1 - 0.12 11.2 0.0 0.27 10.0 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 OAP57919.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TRI12 PF06609.8 OAP57920.1 - 1.3e-51 175.5 14.9 1.6e-51 175.2 10.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP57920.1 - 2e-14 53.0 49.9 1e-11 44.1 23.0 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4516 PF14990.1 OAP57920.1 - 0.36 10.4 1.9 1.7 8.2 1.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) Cupin_2 PF07883.6 OAP57921.1 - 6.7e-09 35.1 0.1 1.5e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 OAP57921.1 - 4.6e-06 26.3 0.2 6.1e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 OAP57921.1 - 1e-05 25.0 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 OAP57921.1 - 0.00016 21.3 0.0 0.00025 20.7 0.0 1.3 1 1 0 1 1 1 1 Cupin Cupin_3 PF05899.7 OAP57921.1 - 0.011 15.1 0.8 0.034 13.5 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF861) ADH_N PF08240.7 OAP57922.1 - 1.3e-29 102.1 1.0 2.5e-29 101.2 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP57922.1 - 9.3e-18 64.0 0.3 1.5e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP57922.1 - 0.00035 21.4 0.0 0.0008 20.3 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP57922.1 - 0.043 13.3 0.1 0.082 12.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lactamase_B PF00753.22 OAP57923.1 - 6.4e-09 35.7 1.1 1.3e-08 34.7 0.8 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP57923.1 - 0.0035 16.8 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 OAP57924.1 - 1.1e-18 67.0 0.1 2.1e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CMD PF02627.15 OAP57925.1 - 4e-20 71.4 0.6 5.2e-20 71.0 0.4 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family adh_short PF00106.20 OAP57926.1 - 8.6e-22 77.8 0.0 1.7e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57926.1 - 6.2e-08 32.5 0.2 1.9e-06 27.6 0.1 2.8 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP57926.1 - 0.065 13.0 0.1 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_3 PF13738.1 OAP57927.1 - 1.5e-21 77.3 0.0 6.2e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP57927.1 - 8.2e-18 63.8 2.3 4.8e-16 58.0 1.6 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP57927.1 - 1.6e-07 30.5 0.1 6.6e-06 25.2 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP57927.1 - 8.8e-07 28.8 0.2 3e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP57927.1 - 1.2e-06 28.5 0.0 0.00068 19.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF1618 PF07762.9 OAP57927.1 - 0.02 15.1 0.6 0.054 13.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1618) NAD_binding_9 PF13454.1 OAP57927.1 - 0.035 13.8 0.0 3.5 7.3 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 OAP57927.1 - 0.11 11.6 0.0 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 OAP57927.1 - 0.13 11.0 0.2 2.3 7.0 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP57927.1 - 0.2 12.0 0.3 32 5.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.8 OAP57928.1 - 1.7e-44 151.9 0.1 3.4e-44 150.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP57928.1 - 4.9e-14 51.9 0.1 1.1e-13 50.7 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAP57928.1 - 0.00046 19.9 0.1 0.00072 19.3 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 OAP57928.1 - 0.049 12.8 0.1 0.083 12.1 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF498 PF04430.9 OAP57928.1 - 0.053 13.0 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DUF2424 PF10340.4 OAP57928.1 - 0.054 12.1 0.0 0.072 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Pyr_redox_3 PF13738.1 OAP57929.1 - 4.2e-19 69.4 0.0 1e-18 68.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP57929.1 - 2.1e-13 49.3 0.5 9.2e-13 47.2 0.1 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP57929.1 - 4.5e-11 42.6 0.0 9.3e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP57929.1 - 8.4e-07 28.2 0.0 0.0018 17.2 0.0 3.5 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP57929.1 - 8.2e-05 22.4 0.1 0.0039 16.9 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP57929.1 - 0.0004 20.3 0.0 0.0062 16.4 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP57929.1 - 0.0056 16.7 0.0 1.6 8.8 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase PS_pyruv_trans PF04230.8 OAP57929.1 - 0.0098 15.6 0.7 0.08 12.6 0.2 2.5 3 0 0 3 3 3 1 Polysaccharide pyruvyl transferase NAD_Gly3P_dh_N PF01210.18 OAP57929.1 - 0.028 14.1 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ARL2_Bind_BART PF11527.3 OAP57929.1 - 0.083 12.6 1.7 0.38 10.5 0.4 2.2 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART adh_short PF00106.20 OAP57930.1 - 1.2e-26 93.6 0.9 1.8e-26 93.0 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57930.1 - 3.3e-26 92.5 0.0 4.1e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP57930.1 - 2.5e-10 40.3 0.7 3.8e-10 39.7 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAP57930.1 - 0.014 15.0 0.1 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DNA_pol_B_exo2 PF10108.4 OAP57930.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB NmrA PF05368.8 OAP57930.1 - 0.16 11.1 0.2 0.46 9.6 0.0 1.8 2 1 1 3 3 3 0 NmrA-like family Cyclase PF04199.8 OAP57931.1 - 3.1e-13 49.7 0.2 8.8e-13 48.2 0.1 1.6 1 1 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.1 OAP57932.1 - 2.2e-28 99.6 0.0 2.8e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57932.1 - 2.5e-23 82.8 0.0 3.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57932.1 - 7.3e-14 51.8 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 OAP57932.1 - 0.098 11.8 0.1 0.21 10.7 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 OAP57933.1 - 4.6e-28 98.6 0.0 6e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP57933.1 - 2.6e-26 92.5 0.1 3.2e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57933.1 - 5e-10 39.3 0.0 7.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 OAP57933.1 - 0.044 14.1 0.3 0.088 13.2 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 OAP57933.1 - 0.13 12.0 1.0 0.25 11.1 0.7 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 OAP57933.1 - 0.14 11.7 0.4 0.2 11.2 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 OAP57934.1 - 2.4e-14 52.8 0.0 4.7e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SGL PF08450.7 OAP57935.1 - 9.7e-12 44.7 0.1 5e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 OAP57935.1 - 0.00039 20.2 0.1 0.37 10.8 0.0 3.0 2 0 0 2 2 2 2 NHL repeat Arylesterase PF01731.15 OAP57935.1 - 0.07 13.1 0.1 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Arylesterase NAD_binding_2 PF03446.10 OAP57936.1 - 1.7e-24 86.5 0.2 3.1e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP57936.1 - 1.8e-22 79.6 0.0 2.8e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sugar_tr PF00083.19 OAP57937.1 - 9.1e-84 281.6 22.5 1e-83 281.4 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57937.1 - 9.2e-25 87.0 35.5 2e-14 53.0 7.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP57937.1 - 0.07 12.9 9.1 0.52 10.1 0.4 3.7 3 1 0 3 3 3 0 MFS_1 like family Peptidase_M50 PF02163.17 OAP57937.1 - 0.1 11.5 1.9 0.21 10.5 1.3 1.4 1 0 0 1 1 1 0 Peptidase family M50 Sugar_tr PF00083.19 OAP57938.1 - 7.5e-75 252.2 24.4 9.9e-75 251.8 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP57938.1 - 4.7e-17 61.7 28.7 4.7e-17 61.7 19.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3302 PF11742.3 OAP57938.1 - 0.026 14.3 1.3 0.11 12.3 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) NAD_binding_2 PF03446.10 OAP57939.1 - 9.4e-30 103.5 0.1 1.4e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP57939.1 - 1.6e-23 83.0 0.0 3.3e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 OAP57939.1 - 0.044 12.5 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 OAP57939.1 - 0.11 12.9 0.0 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Beta-lactamase PF00144.19 OAP57940.1 - 7.7e-37 127.0 0.0 5.4e-36 124.2 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase YqfQ PF14181.1 OAP57941.1 - 0.018 15.0 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF1661 PF07877.6 OAP57941.1 - 0.2 11.1 0.2 0.2 11.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) DIOX_N PF14226.1 OAP57943.1 - 2.8e-14 53.6 0.0 5.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP57943.1 - 4.6e-10 39.6 0.0 9.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 OAP57944.1 - 2.6e-05 23.2 0.1 4.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 OAP57945.1 - 2.3e-22 79.9 0.2 2.9e-22 79.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP57945.1 - 2.2e-08 33.9 0.0 5.8e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP57945.1 - 1.8e-07 30.9 0.0 2.5e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 OAP57945.1 - 0.045 12.6 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme FAD_binding_2 PF00890.19 OAP57946.1 - 0.0019 17.1 0.3 0.29 9.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain CLN3 PF02487.12 OAP57947.1 - 9.4e-103 344.1 12.9 8.6e-101 337.6 8.9 2.0 1 1 0 1 1 1 1 CLN3 protein Rxt3 PF08642.5 OAP57948.1 - 2.8e-23 82.3 0.0 8e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 OAP57948.1 - 0.00022 21.1 0.0 0.0021 17.9 0.0 2.2 1 1 0 1 1 1 1 LCCL domain DUF1992 PF09350.5 OAP57949.1 - 2.5e-24 84.8 0.1 7.3e-24 83.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DTHCT PF08070.6 OAP57951.1 - 0.032 14.8 5.5 0.032 14.8 3.8 2.3 3 0 0 3 3 3 0 DTHCT (NUC029) region MFS_1 PF07690.11 OAP57952.1 - 6.6e-27 94.1 43.7 9.4e-27 93.6 30.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SecD_SecF PF02355.11 OAP57952.1 - 0.12 11.5 3.0 0.5 9.5 1.1 2.3 2 0 0 2 2 2 0 Protein export membrane protein RBP_receptor PF14752.1 OAP57952.1 - 0.14 10.4 2.6 2.4 6.3 0.0 2.7 2 1 1 3 3 3 0 Retinol binding protein receptor HMGL-like PF00682.14 OAP57953.1 - 5.7e-40 137.4 0.1 5.6e-39 134.2 0.1 2.0 1 1 0 1 1 1 1 HMGL-like SDP_N PF12278.3 OAP57954.1 - 0.67 9.5 6.8 1.2 8.8 4.7 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal LCM PF04072.9 OAP57955.1 - 8.7e-17 61.2 0.0 2e-16 60.0 0.0 1.6 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Cupin_8 PF13621.1 OAP57955.1 - 5.1e-12 45.8 0.0 1.2e-11 44.6 0.0 1.5 2 0 0 2 2 2 1 Cupin-like domain Kelch_4 PF13418.1 OAP57955.1 - 4e-07 29.7 2.2 0.013 15.2 0.0 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain L51_S25_CI-B8 PF05047.11 OAP57959.1 - 1e-06 28.3 0.0 2.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ctr PF04145.10 OAP57960.1 - 5.4e-33 114.0 0.2 7.1e-33 113.6 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family NAD_binding_4 PF07993.7 OAP57962.1 - 0.0012 17.8 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAP57962.1 - 0.002 17.5 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acyl_transf_3 PF01757.17 OAP57963.1 - 1.3e-32 112.9 23.7 2.3e-32 112.1 16.4 1.3 1 0 0 1 1 1 1 Acyltransferase family DUF914 PF06027.7 OAP57964.1 - 6.7e-104 347.3 18.0 8.3e-104 347.0 12.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 OAP57964.1 - 9.4e-05 22.4 11.8 9.4e-05 22.4 8.1 3.0 2 1 1 3 3 3 1 EamA-like transporter family HCV_env PF01539.12 OAP57964.1 - 6.9 6.0 11.3 0.055 12.9 1.6 2.0 2 1 1 3 3 3 0 Hepatitis C virus envelope glycoprotein E1 Ank_2 PF12796.2 OAP57965.1 - 4.1e-29 100.7 0.2 8.9e-19 67.6 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ribosomal_L7Ae PF01248.21 OAP57965.1 - 8.3e-26 89.3 1.1 1.9e-25 88.2 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank_5 PF13857.1 OAP57965.1 - 7.9e-24 83.1 0.4 4.1e-10 39.5 0.0 5.5 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP57965.1 - 2.9e-23 81.7 0.1 3.4e-10 40.1 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 OAP57965.1 - 3.4e-21 73.9 1.8 5.6e-07 29.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 OAP57965.1 - 5.7e-20 69.4 0.1 2.2e-05 24.2 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Steroid_dh PF02544.11 OAP57966.1 - 3.9e-07 29.9 0.7 0.0006 19.5 0.1 2.6 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF4401 PF14351.1 OAP57966.1 - 0.83 8.5 10.0 0.014 14.4 1.7 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4401) BCS1_N PF08740.6 OAP57967.1 - 6e-27 94.4 0.0 1.2e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 OAP57967.1 - 1.7e-15 57.3 0.0 9.3e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAP57967.1 - 0.00016 22.4 0.0 0.00016 22.4 0.0 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 OAP57967.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 OAP57967.1 - 0.0026 17.4 0.0 0.011 15.4 0.0 2.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 OAP57967.1 - 0.0078 15.6 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 OAP57967.1 - 0.012 15.2 1.3 0.089 12.3 0.5 2.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAP57967.1 - 0.02 14.8 0.1 0.071 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 OAP57967.1 - 0.029 13.7 0.0 0.069 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAP57967.1 - 0.032 14.3 0.0 0.095 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAP57967.1 - 0.079 12.8 0.0 0.079 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 OAP57967.1 - 0.087 13.1 0.0 0.087 13.1 0.0 2.9 2 1 0 2 2 1 0 AAA domain CbiA PF01656.18 OAP57967.1 - 0.096 12.0 0.4 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PCEMA1 PF07418.6 OAP57967.1 - 0.16 11.3 9.8 0.27 10.5 6.8 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Scs3p PF10261.4 OAP57968.1 - 8e-59 198.5 6.2 1.2e-58 198.0 4.3 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Cytochrom_B561 PF03188.11 OAP57969.1 - 1.2e-08 34.8 10.7 2.3e-08 33.9 7.4 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Herpes_gE PF02480.11 OAP57969.1 - 0.00073 17.9 0.0 0.0016 16.7 0.0 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF2306 PF10067.4 OAP57969.1 - 0.0083 16.2 2.0 0.0083 16.2 1.4 2.7 2 1 1 3 3 3 1 Predicted membrane protein (DUF2306) PepSY_TM_1 PF13172.1 OAP57969.1 - 1.2 8.9 6.8 0.074 12.8 0.5 2.3 2 0 0 2 2 2 0 PepSY-associated TM helix DUF1510 PF07423.6 OAP57969.1 - 6.8 5.9 11.4 0.25 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nitroreductase PF00881.19 OAP57970.1 - 3e-12 46.6 0.0 8.8e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 Nitroreductase family p450 PF00067.17 OAP57971.1 - 6.6e-68 229.3 0.0 7.9e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stm1_N PF09598.5 OAP57972.1 - 5.9e-13 49.3 4.3 5.9e-13 49.3 3.0 4.2 4 2 0 4 4 4 1 Stm1 PNK3P PF08645.6 OAP57972.1 - 0.081 12.3 0.2 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase DUF4410 PF14366.1 OAP57972.1 - 0.084 12.6 1.2 0.15 11.8 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) mIF3 PF14877.1 OAP57972.1 - 0.11 11.8 0.6 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor bZIP_1 PF00170.16 OAP57973.1 - 1.3e-05 25.0 7.0 2.2e-05 24.3 4.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP57973.1 - 0.0014 18.4 7.7 0.0027 17.4 5.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DUF4407 PF14362.1 OAP57973.1 - 0.086 11.7 1.4 0.14 11.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glutaredoxin2_C PF04399.8 OAP57973.1 - 0.22 11.1 2.2 0.2 11.2 0.5 1.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Fib_alpha PF08702.5 OAP57973.1 - 0.24 11.5 2.3 0.44 10.6 1.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family bZIP_Maf PF03131.12 OAP57973.1 - 3.4 8.0 11.4 0.52 10.6 5.1 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Arrestin_C PF02752.17 OAP57974.1 - 1.7e-10 41.1 0.6 2.9e-09 37.1 0.3 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain adh_short PF00106.20 OAP57975.1 - 7e-21 74.8 0.4 1e-20 74.3 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP57975.1 - 4e-18 66.0 0.0 5.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP57975.1 - 2.3e-07 30.6 0.1 3.9e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP57975.1 - 0.0031 16.9 0.0 0.0069 15.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAP57975.1 - 0.073 13.1 0.0 0.84 9.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 OAP57975.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyoxalase_3 PF13468.1 OAP57976.1 - 1.6e-20 73.7 0.0 9.9e-20 71.1 0.0 2.2 2 1 0 2 2 2 1 Glyoxalase-like domain SMK-1 PF04802.10 OAP57977.1 - 2.4e-73 245.7 7.0 4.8e-73 244.8 4.9 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 MBOAT_2 PF13813.1 OAP57978.1 - 4.6e-17 61.8 0.7 4.6e-17 61.8 0.5 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family 2OG-FeII_Oxy_2 PF13532.1 OAP57979.1 - 1.2e-13 51.3 0.0 1.9e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAP57979.1 - 6e-06 26.4 0.0 9.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Polysacc_deac_1 PF01522.16 OAP57980.1 - 4.5e-20 71.5 0.0 8.9e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 OAP57980.1 - 0.037 13.4 0.2 0.1 12.0 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) HeH PF12949.2 OAP57980.1 - 0.072 12.6 0.2 4 7.0 0.0 2.8 3 0 0 3 3 3 0 HeH/LEM domain Git3 PF11710.3 OAP57981.1 - 5.9e-09 35.7 9.5 5.9e-09 35.7 6.6 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 OAP57981.1 - 9.8e-08 31.2 6.9 9.8e-08 31.2 4.8 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor TRI12 PF06609.8 OAP57982.1 - 1.8e-34 118.9 11.4 2.2e-34 118.6 7.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP57982.1 - 9.8e-19 67.2 42.4 9.8e-19 67.2 29.4 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF872 PF05915.7 OAP57982.1 - 0.33 10.8 3.4 0.42 10.4 0.4 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Lactonase PF10282.4 OAP57983.1 - 0.00057 19.0 0.0 0.028 13.5 0.0 2.9 2 2 1 3 3 3 1 Lactonase, 7-bladed beta-propeller bZIP_1 PF00170.16 OAP57984.1 - 0.00084 19.2 8.7 0.0016 18.3 6.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor G-gamma PF00631.17 OAP57984.1 - 0.016 14.8 1.6 0.023 14.4 0.0 2.0 2 0 0 2 2 2 0 GGL domain E_Pc_C PF06752.7 OAP57984.1 - 2.8 7.3 8.4 1.4 8.3 4.2 1.7 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus BAG PF02179.11 OAP57986.1 - 1e-12 47.9 0.1 2.3e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.18 OAP57986.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF605 PF04652.11 OAP57986.1 - 0.51 9.6 10.6 0.21 10.9 6.0 1.4 2 0 0 2 2 2 0 Vta1 like Radical_SAM PF04055.16 OAP57988.1 - 2.4e-13 50.6 0.0 3.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF2763 PF10961.3 OAP57989.1 - 0.029 14.7 7.0 6.8 7.1 5.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Meth_synt_2 PF01717.13 OAP57990.1 - 1.2e-07 31.0 0.0 0.0007 18.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain FBP PF07299.6 OAP57991.1 - 0.055 12.7 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) TPR_MLP1_2 PF07926.7 OAP57992.1 - 2.4e-27 95.2 28.2 2.4e-27 95.2 19.5 17.4 2 2 9 13 13 13 2 TPR/MLP1/MLP2-like protein TFIIE_beta PF02186.10 OAP57993.1 - 0.043 13.8 0.1 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 TFIIE beta subunit core domain NfeD PF01957.13 OAP57994.1 - 0.019 15.1 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4381 PF14316.1 OAP57994.1 - 0.041 13.9 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2500 PF10694.4 OAP57994.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) YebO PF13974.1 OAP57994.1 - 0.82 9.4 4.2 1.3 8.8 2.9 1.3 1 0 0 1 1 1 0 YebO-like protein RCR PF12273.3 OAP57994.1 - 1.8 9.1 12.7 11 6.6 8.8 2.3 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DHBP_synthase PF00926.14 OAP57995.1 - 1.1e-75 253.1 0.1 3.5e-75 251.4 0.1 1.7 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase SIR2 PF02146.12 OAP57996.1 - 4.2e-30 104.7 0.0 1.5e-11 44.3 0.0 3.3 3 0 0 3 3 3 3 Sir2 family zf-trcl PF13451.1 OAP57996.1 - 0.062 12.9 1.5 0.15 11.7 1.0 1.6 1 0 0 1 1 1 0 Probable zinc-binding domain PIP49_C PF12260.3 OAP57997.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Epimerase PF01370.16 OAP57999.1 - 1.5e-18 67.0 0.0 2.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP57999.1 - 9.7e-15 55.0 0.2 1.5e-14 54.4 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 OAP57999.1 - 7e-11 41.5 0.0 8.2e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 OAP57999.1 - 7.2e-09 34.7 0.0 1e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 OAP57999.1 - 3.5e-07 29.7 0.2 6.2e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 OAP57999.1 - 2.3e-06 26.8 0.1 3.3e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 OAP57999.1 - 1.9e-05 23.7 0.2 0.00026 19.9 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein TrkA_N PF02254.13 OAP57999.1 - 0.0002 21.3 0.2 0.00061 19.7 0.2 1.8 1 1 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 OAP57999.1 - 0.0018 18.2 0.4 0.0036 17.2 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP57999.1 - 0.012 15.2 0.6 0.026 14.1 0.4 1.5 1 1 0 1 1 1 0 KR domain ResIII PF04851.10 OAP58000.1 - 1.5e-20 73.8 0.0 4e-20 72.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAP58000.1 - 8.3e-12 44.8 0.1 2.5e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP58000.1 - 6e-11 42.1 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 OAP58000.1 - 0.038 12.9 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Iso_dh PF00180.15 OAP58001.1 - 6.2e-98 327.9 0.0 7.6e-98 327.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 OAP58002.1 - 2.3e-36 125.2 0.0 1.4e-35 122.6 0.0 2.4 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 OAP58002.1 - 3.1e-06 26.9 0.0 1.6e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 OppC_N PF12911.2 OAP58002.1 - 0.21 11.0 0.7 0.6 9.5 0.1 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Eaf7 PF07904.8 OAP58003.1 - 6.5e-21 74.1 0.0 1.6e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Nop14 PF04147.7 OAP58003.1 - 0.58 8.0 9.1 0.65 7.8 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAP58003.1 - 0.73 8.2 13.3 0.19 10.1 5.8 1.9 2 0 0 2 2 2 0 Daxx Family Clr5 PF14420.1 OAP58004.1 - 0.003 17.4 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 Clr5 domain MFS_1 PF07690.11 OAP58005.1 - 2.2e-43 148.3 32.5 3.4e-43 147.7 22.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 OAP58006.1 - 4.9e-39 134.0 13.2 1.7e-32 112.5 6.6 2.3 2 0 0 2 2 2 2 Spc97 / Spc98 family DUF3460 PF11943.3 OAP58006.1 - 0.0034 17.4 0.1 0.0075 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3460) UPF0102 PF02021.12 OAP58006.1 - 0.057 13.3 0.0 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0102 DUF2236 PF09995.4 OAP58007.1 - 5.4e-37 127.3 0.1 9.2e-37 126.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TMEM223 PF14640.1 OAP58007.1 - 0.093 12.6 0.0 8.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Transmembrane protein 223 Neugrin PF06413.6 OAP58008.1 - 1.8e-16 60.6 1.7 2.6e-16 60.1 1.2 1.4 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 OAP58008.1 - 3.8e-10 39.9 3.1 6.7e-10 39.1 2.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 OAP58008.1 - 0.00021 21.3 2.2 0.00032 20.8 0.1 2.4 2 1 0 3 3 3 1 Winged helix-turn helix Glyco_tranf_2_3 PF13641.1 OAP58009.1 - 6.7e-33 114.3 0.0 1.1e-32 113.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAP58009.1 - 1.7e-17 63.7 1.7 1.7e-17 63.7 1.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 OAP58009.1 - 2.8e-12 46.6 0.0 4.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 OAP58009.1 - 1.4e-10 40.1 3.0 9.3e-09 34.1 0.1 2.9 2 1 1 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.1 OAP58009.1 - 1.3e-09 37.5 0.0 3.4e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 OAP58009.1 - 0.00022 20.4 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3353 PF11833.3 OAP58009.1 - 0.044 13.2 0.1 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Acyl-CoA_ox_N PF14749.1 OAP58010.1 - 6.1e-21 75.0 0.1 1.4e-20 73.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAP58010.1 - 2e-09 36.7 0.1 7.8e-09 34.9 0.1 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.14 OAP58010.1 - 2.5e-08 33.5 0.1 4.3e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.19 OAP58010.1 - 3.2e-05 24.0 0.6 7.1e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HET PF06985.6 OAP58011.1 - 3.7e-33 114.6 1.0 6.7e-33 113.7 0.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Adeno_E3_CR2 PF02439.10 OAP58013.1 - 0.072 12.6 0.5 0.17 11.4 0.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 OAP58013.1 - 0.48 9.7 6.8 0.28 10.5 2.2 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Abhydrolase_6 PF12697.2 OAP58014.1 - 2.1e-29 103.0 0.1 5.2e-29 101.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP58014.1 - 3.1e-16 59.6 0.0 3.9e-14 52.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP58014.1 - 3.4e-15 56.0 0.0 1.1e-14 54.3 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAP58014.1 - 6.1e-05 22.7 0.0 0.00012 21.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 OAP58014.1 - 0.0088 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 OAP58014.1 - 0.012 15.4 0.1 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 OAP58014.1 - 0.076 12.2 0.1 2.6 7.1 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family Mem_trans PF03547.13 OAP58015.1 - 1.8e-24 85.7 0.0 5.2e-24 84.2 0.0 1.6 1 1 0 1 1 1 1 Membrane transport protein TMEM169 PF15052.1 OAP58015.1 - 0.00066 19.5 0.8 0.0026 17.6 0.6 2.0 1 0 0 1 1 1 1 TMEM169 protein family Vac_ImportDeg PF09783.4 OAP58016.1 - 2.7e-26 92.1 0.0 1.4e-17 63.7 0.0 3.8 2 1 0 2 2 2 2 Vacuolar import and degradation protein Abhydrolase_6 PF12697.2 OAP58017.1 - 1.9e-29 103.1 0.2 2.3e-29 102.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP58017.1 - 6.4e-19 68.4 0.0 4.9e-17 62.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP58017.1 - 1.7e-08 34.3 0.0 6.6e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 OAP58017.1 - 1.2e-06 28.3 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 OAP58017.1 - 0.00028 20.6 0.0 0.00072 19.3 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Esterase_phd PF10503.4 OAP58017.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase p450 PF00067.17 OAP58018.1 - 5.1e-59 200.0 0.0 7.8e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PHD PF00628.24 OAP58018.1 - 2.2e-11 43.2 7.5 2.2e-11 43.2 5.2 2.2 2 0 0 2 2 2 1 PHD-finger zf-C2H2_4 PF13894.1 OAP58018.1 - 0.02 15.1 1.0 0.02 15.1 0.7 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 OAP58018.1 - 0.092 12.9 0.3 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Tannase PF07519.6 OAP58019.1 - 3.5e-90 303.0 1.8 4.7e-90 302.5 1.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 OAP58019.1 - 0.002 18.0 0.4 0.0064 16.3 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP58019.1 - 0.0029 17.1 0.4 0.0093 15.5 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Sugar_tr PF00083.19 OAP58020.1 - 2e-89 300.2 16.3 2.3e-89 300.0 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58020.1 - 8e-27 93.8 48.1 3.1e-23 82.0 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP58020.1 - 3.1e-05 22.5 9.6 0.011 14.2 0.9 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Fungal_trans PF04082.13 OAP58021.1 - 4e-19 68.5 0.0 7.1e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58021.1 - 1.6e-09 37.4 12.8 3e-09 36.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KIAA1430 PF13879.1 OAP58021.1 - 0.084 13.3 0.7 0.18 12.2 0.5 1.5 1 0 0 1 1 1 0 KIAA1430 homologue DUF1446 PF07287.6 OAP58022.1 - 2.4e-119 398.0 0.1 2.9e-119 397.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) NaeI PF09126.5 OAP58022.1 - 0.16 10.6 0.0 5.8 5.4 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease NaeI FAD_binding_3 PF01494.14 OAP58023.1 - 3.7e-88 295.9 0.0 6.5e-88 295.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 OAP58023.1 - 1.1e-57 194.3 0.0 2e-57 193.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 OAP58023.1 - 0.00015 20.9 0.0 0.0093 15.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 OAP58023.1 - 0.00039 19.0 0.1 0.00061 18.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAP58023.1 - 0.00042 20.2 0.1 0.0014 18.5 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP58023.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP58023.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 OAP58023.1 - 0.035 14.4 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP58023.1 - 0.055 12.3 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP58023.1 - 0.065 13.2 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.1 OAP58023.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain DUF3425 PF11905.3 OAP58024.1 - 2.8e-19 69.3 1.8 1.3e-18 67.2 0.5 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) zf-C2H2 PF00096.21 OAP58025.1 - 1.4e-12 47.1 13.4 5e-06 26.5 3.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP58025.1 - 3.8e-10 39.3 11.3 5.4e-05 23.2 2.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 OAP58025.1 - 5e-08 32.8 3.2 0.0011 19.0 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 OAP58025.1 - 5.2e-08 32.5 2.5 0.00039 20.2 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAP58025.1 - 7.6e-07 29.0 1.2 0.026 14.6 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 OAP58025.1 - 1.3e-06 28.3 15.2 9.3e-06 25.6 2.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 OAP58025.1 - 0.0013 18.8 3.6 0.0034 17.4 2.5 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.9 OAP58025.1 - 0.0035 16.7 1.7 1 8.8 0.2 2.3 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C2HC_2 PF13913.1 OAP58025.1 - 0.0089 15.6 2.5 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-RING_2 PF13639.1 OAP58025.1 - 0.052 13.3 0.5 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Ring finger domain DUF2225 PF09986.4 OAP58025.1 - 0.059 12.8 2.5 0.81 9.1 0.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) LIM PF00412.17 OAP58025.1 - 0.075 13.1 0.5 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 LIM domain zf-C2H2_2 PF12756.2 OAP58025.1 - 0.13 12.3 2.0 8 6.6 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Prok-RING_4 PF14447.1 OAP58025.1 - 0.59 9.7 3.0 10 5.7 0.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ldh_1_N PF00056.18 OAP58026.1 - 1.8e-28 99.1 0.1 5.1e-28 97.6 0.0 1.8 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 OAP58026.1 - 3.7e-28 98.4 0.0 5.1e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.16 OAP58026.1 - 0.058 13.2 0.7 0.22 11.3 0.2 2.1 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.12 OAP58026.1 - 0.096 13.1 0.1 0.55 10.7 0.1 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 OAP58026.1 - 0.13 12.2 0.1 0.35 10.8 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain DAO PF01266.19 OAP58026.1 - 0.64 8.8 3.6 0.43 9.4 1.1 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase PPDK_N PF01326.14 OAP58027.1 - 1.2e-91 307.1 0.0 2.1e-91 306.4 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 OAP58027.1 - 5.2e-60 202.7 0.0 8.6e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 OAP58027.1 - 4.8e-25 86.9 1.1 1.3e-24 85.5 0.8 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain zf-C2H2 PF00096.21 OAP58028.1 - 7.1e-07 29.2 17.7 1.6e-05 24.9 1.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP58028.1 - 4.6e-05 23.5 3.8 4.6e-05 23.5 2.6 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP58028.1 - 0.001 19.2 0.9 0.001 19.2 0.6 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAP58028.1 - 0.0012 18.9 0.7 0.0032 17.5 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 OAP58028.1 - 3.8 7.9 10.1 0.32 11.4 1.7 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 OAP58028.1 - 7.2 6.7 7.4 43 4.2 4.3 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Fungal_trans PF04082.13 OAP58029.1 - 6.4e-28 97.3 0.0 1.1e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58029.1 - 2.1e-11 43.5 12.6 3.9e-11 42.6 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3902 PF13042.1 OAP58029.1 - 0.15 11.3 0.1 0.15 11.3 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) Sugar_tr PF00083.19 OAP58030.1 - 1.1e-99 334.0 13.3 1.3e-99 333.8 9.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58030.1 - 5.9e-27 94.3 17.2 5.9e-27 94.3 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP58030.1 - 8e-05 21.0 1.0 0.00017 19.9 0.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 OAP58030.1 - 0.00064 18.2 14.6 0.00072 18.0 0.1 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein SPC25 PF06703.6 OAP58030.1 - 0.0048 16.4 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) SERTA PF06031.8 OAP58030.1 - 0.2 10.9 1.6 0.69 9.2 0.1 2.3 2 1 0 2 2 2 0 SERTA motif Ras PF00071.17 OAP58032.1 - 8e-56 187.8 0.0 9.1e-56 187.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP58032.1 - 1.2e-17 64.4 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP58032.1 - 1.7e-08 33.8 0.0 2.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAP58032.1 - 0.00099 18.5 0.0 0.0041 16.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MAM1 PF10434.4 OAP58032.1 - 0.04 13.0 0.1 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 RRM_1 PF00076.17 OAP58033.1 - 2.9e-18 65.2 0.0 5.3e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP58033.1 - 1.3e-13 50.6 0.0 2.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 OAP58034.1 - 1.9e-38 132.1 0.0 2.9e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58034.1 - 4e-28 98.1 0.0 6e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP58034.1 - 0.00048 19.9 0.5 1.5 8.4 0.0 3.4 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 OAP58034.1 - 0.00077 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAP58034.1 - 0.011 14.7 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med10 PF09748.4 OAP58035.1 - 2.5e-33 114.6 0.2 3.6e-33 114.1 0.1 1.3 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 OAP58035.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Chalcone PF02431.10 OAP58036.1 - 1.3e-59 200.9 0.0 1.6e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Auts2 PF15336.1 OAP58036.1 - 0.0037 17.3 1.2 0.0037 17.3 0.9 2.5 3 0 0 3 3 3 1 Autism susceptibility gene 2 protein Glutaredoxin PF00462.19 OAP58037.1 - 2.3e-18 65.9 0.0 3.4e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 OAP58037.1 - 0.0019 17.7 0.0 0.0021 17.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 OAP58037.1 - 0.0086 16.3 0.1 0.011 15.9 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 OAP58037.1 - 0.011 15.7 0.3 0.79 9.7 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 OAP58037.1 - 0.018 15.2 0.1 0.061 13.5 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.1 OAP58037.1 - 0.031 13.7 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 OAP58037.1 - 0.039 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.1 OAP58037.1 - 0.043 13.8 0.1 0.071 13.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like DSBA PF01323.15 OAP58037.1 - 0.047 13.2 0.2 0.46 10.0 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Redoxin PF08534.5 OAP58037.1 - 0.057 12.9 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin PF00085.15 OAP58037.1 - 0.094 12.4 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.1 OAP58037.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DnaJ PF00226.26 OAP58039.1 - 9.6e-21 73.3 1.7 2e-20 72.2 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain zf-UBR PF02207.15 OAP58040.1 - 1.5 8.6 7.4 0.36 10.5 1.9 2.3 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Lipase_3 PF01764.20 OAP58041.1 - 6.8e-17 61.3 0.0 1.1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 OAP58041.1 - 0.0015 18.4 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP58041.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP58041.1 - 0.042 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.3 OAP58041.1 - 0.2 10.9 0.3 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) NS3_envE PF02723.9 OAP58042.1 - 0.92 9.4 4.5 2.5 8.0 3.1 1.7 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E IncA PF04156.9 OAP58042.1 - 1.7 8.2 5.6 3.1 7.3 3.9 1.4 1 0 0 1 1 1 0 IncA protein Methyltransf_23 PF13489.1 OAP58043.1 - 1.5e-19 70.3 0.0 2.2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP58043.1 - 3.5e-09 37.0 0.0 7.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP58043.1 - 4.9e-09 36.5 0.0 1.2e-07 32.1 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP58043.1 - 7.9e-08 32.8 0.0 1.6e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP58043.1 - 9.4e-07 28.5 0.0 3.2e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP58043.1 - 3.9e-05 23.9 0.0 0.00015 22.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP58043.1 - 0.014 15.4 0.0 0.04 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 OAP58043.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 OAP58043.1 - 0.026 13.6 0.0 0.41 9.7 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 OAP58043.1 - 0.027 13.6 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 OAP58043.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.17 OAP58044.1 - 3.2e-63 213.8 0.0 4e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Haem_oxygenas_2 PF14518.1 OAP58044.1 - 0.038 14.1 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Iron-containing redox enzyme HET PF06985.6 OAP58045.1 - 2.3e-07 31.0 0.2 0.006 16.7 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 OAP58046.1 - 4.2e-24 85.2 0.0 1.6e-23 83.4 0.0 2.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 OAP58046.1 - 1.4e-08 34.5 5.9 0.0048 16.8 0.1 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP58046.1 - 0.0001 22.5 3.5 0.14 12.5 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAP58046.1 - 0.00022 21.0 4.5 0.91 9.5 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 OAP58046.1 - 0.021 14.9 7.0 2.6 8.2 1.9 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MCPsignal PF00015.16 OAP58046.1 - 0.19 11.2 0.4 0.42 10.1 0.3 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TPR_2 PF07719.12 OAP58046.1 - 0.44 10.5 4.0 3.7 7.6 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP58046.1 - 0.67 10.5 4.2 3.5 8.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Sigma70_r3 PF04539.11 OAP58046.1 - 3.1 7.7 8.5 4.2 7.3 0.4 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 HATPase_c_3 PF13589.1 OAP58047.1 - 0.0099 15.5 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.1 OAP58047.1 - 0.012 15.3 0.0 0.054 13.2 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3883) HET PF06985.6 OAP58048.1 - 1.2e-20 74.1 0.0 2.2e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 OAP58048.1 - 7e-12 45.5 0.0 8.9e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAP58048.1 - 1.2e-11 43.8 1.9 0.016 14.9 0.0 5.0 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 OAP58048.1 - 1.7e-09 37.6 0.5 4e-06 26.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP58048.1 - 1.8e-06 27.6 0.4 0.33 11.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 OAP58048.1 - 6e-06 26.6 0.3 0.0026 18.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) SIM_C PF06621.7 OAP58048.1 - 0.1 12.1 0.4 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 Single-minded protein C-terminus ADH_N PF08240.7 OAP58049.1 - 2.5e-26 91.5 1.5 5.7e-26 90.4 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP58049.1 - 9.9e-24 83.3 0.7 1.6e-23 82.6 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP58049.1 - 1.2e-05 26.1 0.4 2.1e-05 25.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP58049.1 - 0.015 14.8 0.3 0.027 14.0 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3425 PF11905.3 OAP58050.1 - 7.9e-23 80.8 0.2 1.7e-22 79.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP58050.1 - 0.00049 20.0 10.2 0.0033 17.3 6.2 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 OAP58050.1 - 0.21 11.4 7.6 1.9 8.3 3.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Sugar_tr PF00083.19 OAP58051.1 - 7.1e-74 249.0 22.5 8.4e-74 248.7 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58051.1 - 3.7e-18 65.3 40.6 1.8e-13 49.9 5.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.13 OAP58052.1 - 1.6e-08 34.0 0.0 3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) JSRP PF15312.1 OAP58052.1 - 0.12 12.3 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Myotub-related PF06602.9 OAP58053.1 - 6.3e-124 413.3 0.0 9.2e-124 412.7 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 OAP58054.1 - 2.3e-21 75.7 0.0 4.8e-20 71.4 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Metallophos PF00149.23 OAP58057.1 - 1.3e-09 37.7 0.6 2.4e-09 36.8 0.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP58057.1 - 3.1e-07 30.3 0.0 7.7e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDO_I PF05995.7 OAP58059.1 - 4.6e-39 133.3 0.1 5.6e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 OAP58059.1 - 3.7e-06 26.4 0.1 6.3e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) TGS PF02824.16 OAP58060.1 - 1.4e-22 79.3 0.1 2.7e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 OAP58060.1 - 4.6e-18 65.2 0.0 1e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP58060.1 - 2.6e-09 36.5 0.1 1.8e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 OAP58060.1 - 2.5e-05 23.7 0.1 0.36 10.2 0.0 3.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 OAP58060.1 - 0.0005 19.9 0.1 0.1 12.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 OAP58060.1 - 0.0046 15.7 0.3 0.014 14.1 0.1 1.9 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 OAP58060.1 - 0.015 15.8 0.0 0.049 14.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein DUF211 PF02680.9 OAP58060.1 - 0.03 14.1 1.1 0.11 12.3 0.2 2.2 2 1 0 3 3 3 0 Uncharacterized ArCR, COG1888 AAA_28 PF13521.1 OAP58060.1 - 0.13 12.2 0.1 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc5 PF03221.11 OAP58061.1 - 7.6e-11 41.6 0.1 1.6e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_38 PF13936.1 OAP58061.1 - 7.6e-06 25.3 0.6 1.5e-05 24.4 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.8 OAP58061.1 - 0.00052 19.3 1.4 0.00052 19.3 0.9 1.9 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 OAP58061.1 - 0.00053 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.1 OAP58061.1 - 0.006 16.2 0.3 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.11 OAP58061.1 - 0.0088 15.3 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 OAP58061.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_24 PF13412.1 OAP58061.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 OAP58061.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 MarR family PXA PF02194.10 OAP58062.1 - 9.3e-42 142.6 1.2 1.8e-41 141.7 0.4 1.7 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 OAP58062.1 - 0.0036 17.3 0.0 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal IU_nuc_hydro PF01156.14 OAP58063.1 - 4.1e-85 285.7 0.0 4.7e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase A_deamin PF02137.13 OAP58064.1 - 4.4e-22 78.8 0.0 5.9e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF3403 PF11883.3 OAP58064.1 - 0.12 12.6 0.0 23 5.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) Fungal_trans PF04082.13 OAP58065.1 - 6.8e-26 90.6 0.0 1.3e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58065.1 - 2.7e-09 36.7 10.6 4.3e-09 36.1 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.10 OAP58066.1 - 5.1e-08 32.2 0.0 6.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 OAP58066.1 - 1.9e-05 24.4 0.0 0.0087 15.8 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 OAP58066.1 - 4.5e-05 22.8 0.0 7.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 ERG4_ERG24 PF01222.12 OAP58067.1 - 2.5e-158 527.1 0.8 3e-158 526.8 0.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 OAP58067.1 - 0.0012 18.1 0.8 0.0053 16.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) MFS_1 PF07690.11 OAP58068.1 - 2.4e-25 89.0 21.3 2.4e-25 89.0 14.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP58068.1 - 5.1e-06 24.9 2.2 5.1e-06 24.9 1.6 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 OAP58069.1 - 5.6e-31 107.6 0.1 7.2e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58069.1 - 1.1e-11 45.0 0.0 1.3e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58069.1 - 1.7e-11 44.1 0.1 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP58069.1 - 1.6e-05 24.4 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 OAP58070.1 - 1.6e-71 240.9 0.0 2e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP58070.1 - 1.6e-11 45.0 0.0 1.9e-10 41.5 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain CoA_transf_3 PF02515.12 OAP58071.1 - 8.8e-54 181.6 0.4 1.4e-53 180.9 0.3 1.3 1 0 0 1 1 1 1 CoA-transferase family III p450 PF00067.17 OAP58072.1 - 4.9e-70 236.3 0.0 6.1e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAP58073.1 - 1e-72 245.2 0.0 1.3e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SUR7 PF06687.7 OAP58075.1 - 2.4e-34 118.7 3.3 3e-34 118.4 2.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 OAP58075.1 - 2.5e-06 27.2 11.3 2.5e-06 27.2 7.8 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 OAP58075.1 - 0.0039 16.4 1.1 0.006 15.8 0.8 1.3 1 0 0 1 1 1 1 Clc-like Fig1 PF12351.3 OAP58075.1 - 0.0045 16.8 1.0 0.0045 16.8 0.7 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Amastin PF07344.6 OAP58075.1 - 0.018 14.6 7.1 0.037 13.6 4.9 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein PMP22_Claudin PF00822.15 OAP58075.1 - 0.019 14.6 8.1 0.033 13.8 5.6 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family BPD_transp_2 PF02653.11 OAP58075.1 - 0.43 9.5 10.7 0.01 14.8 2.4 1.7 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component DUF4064 PF13273.1 OAP58075.1 - 1.3 9.1 5.2 13 5.9 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Rogdi_lz PF10259.4 OAP58076.1 - 2.7e-68 230.0 0.0 3e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein KSR1-SAM PF13543.1 OAP58077.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 AMP-binding PF00501.23 OAP58078.1 - 2.5e-60 204.0 0.0 3.4e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP58078.1 - 2e-05 25.4 0.1 5.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 OAP58079.1 - 4.1e-66 222.6 0.2 8.9e-66 221.5 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAP58079.1 - 2e-47 159.6 0.2 4.8e-47 158.4 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 OAP58079.1 - 0.00085 19.2 0.0 0.0028 17.6 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cupin_2 PF07883.6 OAP58080.1 - 1.6e-10 40.3 0.0 2.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 OAP58080.1 - 1.4e-05 24.8 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 OAP58080.1 - 0.031 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) CENP-C_C PF11699.3 OAP58080.1 - 0.037 14.0 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_6 PF12852.2 OAP58080.1 - 0.084 12.4 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Cupin EutQ PF06249.7 OAP58080.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Glyco_hydro_1 PF00232.13 OAP58081.1 - 3e-159 530.0 0.0 3.7e-159 529.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 MFS_2 PF13347.1 OAP58082.1 - 5.7e-10 38.1 9.3 1.7e-09 36.6 5.0 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 OAP58082.1 - 9.8e-09 34.3 23.7 2.9e-08 32.8 10.3 2.9 3 1 0 3 3 3 2 Major Facilitator Superfamily DUF2837 PF10997.3 OAP58082.1 - 0.01 15.0 0.2 0.032 13.3 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2837) YfzA PF14118.1 OAP58082.1 - 0.04 14.0 3.0 0.27 11.3 0.1 3.1 2 1 1 3 3 3 0 YfzA-like protein DUF2518 PF10726.4 OAP58082.1 - 0.32 10.5 4.0 0.11 12.0 0.2 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) Yip1 PF04893.12 OAP58083.1 - 0.007 15.8 2.4 0.0079 15.7 1.7 1.1 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 OAP58083.1 - 0.012 15.3 0.4 0.014 15.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF3980 PF13140.1 OAP58083.1 - 0.033 14.4 1.5 0.041 14.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) MIG-14_Wnt-bd PF06664.7 OAP58083.1 - 0.06 12.1 0.1 0.07 11.9 0.0 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion CoA_binding PF02629.14 OAP58084.1 - 1.2e-26 93.0 3.7 6.9e-26 90.6 0.4 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 OAP58084.1 - 6.5e-23 81.0 0.4 9.9e-23 80.4 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 OAP58084.1 - 2.6e-07 30.3 0.1 4.8e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 OAP58084.1 - 0.0034 17.5 0.0 0.0099 16.0 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Sugar_tr PF00083.19 OAP58085.1 - 9e-106 354.1 33.9 1e-105 353.9 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58085.1 - 1e-33 116.5 25.0 1e-33 116.5 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily V-SNARE PF05008.10 OAP58085.1 - 0.028 14.5 0.4 0.05 13.7 0.3 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Fungal_trans_2 PF11951.3 OAP58086.1 - 3.1e-07 29.3 0.1 3.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4063 PF13272.1 OAP58086.1 - 0.26 11.1 1.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) p450 PF00067.17 OAP58087.1 - 1e-57 195.7 0.0 1.4e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APG17 PF04108.7 OAP58087.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Radical_SAM PF04055.16 OAP58088.1 - 2.3e-18 66.9 0.0 4.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 OAP58088.1 - 5.1e-13 48.8 0.0 2.2e-12 46.8 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP58088.1 - 0.016 15.3 0.1 0.049 13.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAP58088.1 - 0.054 13.6 0.1 0.16 12.1 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TP_methylase PF00590.15 OAP58089.1 - 4.2e-47 160.5 0.8 7.8e-47 159.7 0.3 1.6 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 OAP58089.1 - 9.5e-13 48.2 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 OAP58089.1 - 9.9e-08 31.1 0.0 2.8e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 OAP58089.1 - 7.3e-05 21.6 0.1 0.00014 20.7 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central adh_short PF00106.20 OAP58090.1 - 7.3e-17 61.7 1.4 5.6e-16 58.9 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP58090.1 - 1.1e-06 28.4 0.2 0.016 14.8 0.0 2.6 3 0 0 3 3 3 2 KR domain adh_short_C2 PF13561.1 OAP58090.1 - 0.00011 22.0 0.0 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Sod_Cu PF00080.15 OAP58090.1 - 0.0084 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Epimerase PF01370.16 OAP58090.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_transf_90 PF05686.7 OAP58091.1 - 4e-21 75.1 2.5 1.8e-17 63.1 0.4 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 RRS1 PF04939.7 OAP58091.1 - 0.045 13.2 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) His_Phos_1 PF00300.17 OAP58092.1 - 1.5e-18 67.3 0.0 1.8e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HEAT PF02985.17 OAP58093.1 - 2.2e-40 133.1 15.1 0.0018 18.2 0.1 12.5 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.1 OAP58093.1 - 3e-32 110.7 1.6 2.2e-08 34.2 0.0 6.7 2 2 6 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.2 OAP58093.1 - 3.9e-12 46.3 3.3 0.00012 22.4 0.1 6.5 5 2 3 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 OAP58093.1 - 1.2e-09 38.3 10.4 0.03 14.8 0.0 8.0 7 3 3 10 10 9 2 HEAT-like repeat CLASP_N PF12348.3 OAP58093.1 - 2.6e-08 33.4 0.9 0.036 13.3 0.1 4.1 3 1 1 4 4 4 2 CLASP N terminal Adaptin_N PF01602.15 OAP58093.1 - 1.5e-06 26.8 8.3 0.017 13.4 0.2 4.4 2 1 1 4 4 4 2 Adaptin N terminal region MadL PF03817.8 OAP58093.1 - 0.021 14.7 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Malonate transporter MadL subunit Cnd3 PF12719.2 OAP58093.1 - 0.037 13.0 0.2 0.18 10.7 0.1 2.1 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Sp100 PF03172.8 OAP58093.1 - 0.062 13.2 0.1 0.68 9.9 0.0 2.5 2 0 0 2 2 2 0 Sp100 domain Arm PF00514.18 OAP58093.1 - 0.18 11.6 4.3 3.3 7.6 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 OAP58093.1 - 0.7 8.0 4.2 0.79 7.9 0.1 2.7 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit B3_4 PF03483.12 OAP58094.1 - 9.4e-27 93.5 0.0 1.6e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 OAP58094.1 - 1.4e-18 66.5 0.0 9e-15 54.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 OAP58094.1 - 0.0095 15.0 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein Ribosomal_S3_C PF00189.15 OAP58095.1 - 4.5e-17 62.0 0.0 9e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 OAP58095.1 - 2.8e-12 46.0 0.1 4.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 OAP58095.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DEAD PF00270.24 OAP58096.1 - 1.3e-40 138.7 0.0 3.5e-39 134.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP58096.1 - 6.1e-21 74.0 0.1 1.1e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AA_permease_2 PF13520.1 OAP58097.1 - 3.3e-53 180.7 54.6 4.1e-53 180.4 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP58097.1 - 2.7e-17 62.2 45.6 3.7e-17 61.8 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4234 PF14018.1 OAP58097.1 - 0.0019 17.9 0.4 0.0019 17.9 0.3 4.0 5 1 0 5 5 5 1 Domain of unknown function (DUF4234) IF2_assoc PF08364.6 OAP58097.1 - 0.09 12.8 0.5 0.18 11.8 0.2 1.6 2 0 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region CAF-1_p150 PF11600.3 OAP58099.1 - 1.2e-06 28.0 1.0 1.5e-06 27.7 0.7 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Complex1_LYR_2 PF13233.1 OAP58099.1 - 0.088 13.2 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like DUF572 PF04502.8 OAP58099.1 - 2.3 7.3 9.5 3.3 6.8 6.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Glyoxal_oxid_N PF07250.6 OAP58100.1 - 3.6e-17 62.2 0.0 4.4e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 OAP58100.1 - 2e-14 53.4 0.0 3.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) RCC1_2 PF13540.1 OAP58100.1 - 0.061 12.9 0.1 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Glyoxal_oxid_N PF07250.6 OAP58101.1 - 8e-20 70.9 0.0 1.3e-19 70.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus Kelch_4 PF13418.1 OAP58101.1 - 0.011 15.5 0.4 8.7 6.2 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain HEAT PF02985.17 OAP58103.1 - 0.0037 17.2 1.8 5.8 7.2 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat SnoaL_2 PF12680.2 OAP58105.1 - 7.1e-05 23.1 1.7 9.8e-05 22.7 1.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 OAP58105.1 - 0.017 14.6 0.7 0.047 13.2 0.5 1.7 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_3 PF13474.1 OAP58105.1 - 0.021 14.8 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF3421 PF11901.3 OAP58105.1 - 0.044 13.5 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) Pyr_redox_2 PF07992.9 OAP58106.1 - 7.8e-30 104.2 0.0 4.6e-29 101.7 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP58106.1 - 6.7e-13 48.8 0.0 2.8e-09 37.2 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP58106.1 - 0.00017 21.6 0.0 0.012 15.6 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP58106.1 - 0.00028 20.8 0.0 0.21 11.6 0.0 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAP58106.1 - 0.0014 17.7 0.0 0.14 11.1 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 OAP58106.1 - 0.014 14.2 0.1 0.61 8.8 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain FHA PF00498.21 OAP58107.1 - 1.8e-16 60.0 0.0 3.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain SGT1 PF07093.6 OAP58107.1 - 0.00099 17.6 12.7 0.00099 17.6 8.8 1.4 2 0 0 2 2 2 1 SGT1 protein ScpA_ScpB PF02616.9 OAP58107.1 - 1.6 8.2 11.6 0.093 12.2 2.9 2.1 2 0 0 2 2 2 0 ScpA/B protein Myco_19_kDa PF05481.7 OAP58107.1 - 1.9 8.2 6.7 4.4 7.1 4.6 1.5 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen TMCO5 PF14992.1 OAP58107.1 - 3.3 6.7 19.0 5.7 5.9 13.2 1.3 1 0 0 1 1 1 0 TMCO5 family Mnd1 PF03962.10 OAP58107.1 - 3.3 7.3 26.6 1 8.9 5.1 2.4 1 1 1 2 2 2 0 Mnd1 family HSA PF07529.8 OAP58107.1 - 4.4 7.1 13.4 0.16 11.8 3.9 2.3 2 0 0 2 2 2 0 HSA RmuC PF02646.11 OAP58107.1 - 5.4 5.7 19.0 0.012 14.4 4.5 2.3 3 0 0 3 3 3 0 RmuC family Romo1 PF10247.4 OAP58108.1 - 3.8e-20 71.8 18.6 6.1e-20 71.1 12.9 1.3 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 SNARE PF05739.14 OAP58109.1 - 3.1e-18 65.2 1.4 3.1e-18 65.2 0.9 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 OAP58109.1 - 2.6e-15 56.4 0.4 2.6e-15 56.4 0.3 2.7 3 0 0 3 3 3 1 Syntaxin NPV_P10 PF05531.7 OAP58109.1 - 0.0098 16.1 6.1 0.53 10.5 0.3 3.5 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein Syntaxin-18_N PF10496.4 OAP58109.1 - 0.032 14.0 1.1 0.72 9.7 0.0 2.9 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.16 OAP58109.1 - 0.033 13.7 0.2 0.033 13.7 0.1 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 OAP58109.1 - 0.041 13.3 0.4 0.1 12.0 0.3 1.7 1 0 0 1 1 1 0 Integral membrane protein Sed5p BLOC1_2 PF10046.4 OAP58109.1 - 0.67 10.1 4.2 1.3 9.2 0.3 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glyco_hydro_32C PF08244.7 OAP58111.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal Sas10_Utp3 PF04000.10 OAP58112.1 - 2.4e-20 72.5 1.6 5.4e-20 71.3 1.1 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family NPV_P10 PF05531.7 OAP58112.1 - 0.078 13.2 0.8 0.23 11.7 0.1 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ApbA_C PF08546.6 OAP58113.1 - 6.4e-31 106.9 0.0 1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 OAP58113.1 - 1.3e-22 79.8 0.0 1.3e-21 76.6 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA WSC PF01822.14 OAP58117.1 - 0.24 11.3 2.6 0.24 11.3 0.6 1.9 1 1 0 1 1 1 0 WSC domain DUF3433 PF11915.3 OAP58118.1 - 1.1e-30 105.6 19.0 2.6e-24 85.1 1.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) TM_helix PF05552.7 OAP58118.1 - 1.6 8.4 9.6 3.9 7.2 0.3 3.1 3 0 0 3 3 3 0 Conserved TM helix Virul_fac_BrkB PF03631.10 OAP58118.1 - 6.2 6.0 37.6 1.3 8.2 3.2 4.1 4 0 0 4 4 4 0 Virulence factor BrkB Abhydrolase_3 PF07859.8 OAP58119.1 - 3.2e-08 33.3 0.1 4.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP58119.1 - 1.7e-07 30.3 1.2 4.4e-07 28.9 0.8 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAP58119.1 - 2e-07 30.8 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 OAP58119.1 - 3.9e-05 22.4 0.1 0.00041 19.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) DUF1749 PF08538.5 OAP58119.1 - 0.01 14.7 0.0 0.14 11.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.16 OAP58119.1 - 0.029 13.5 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.14 OAP58120.1 - 1.7e-26 93.1 0.0 3.1e-26 92.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP58120.1 - 2.9e-12 46.1 1.7 6.3e-06 25.3 0.6 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP58120.1 - 2.4e-07 30.9 0.0 5.4e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP58120.1 - 4.1e-07 28.8 0.4 9.1e-07 27.6 0.2 1.5 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 OAP58120.1 - 6.7e-06 24.9 2.4 0.0053 15.4 0.9 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 OAP58120.1 - 1.2e-05 24.3 2.4 2.1e-05 23.5 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP58120.1 - 1.5e-05 24.9 2.1 3.6e-05 23.7 1.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAP58120.1 - 0.00037 20.8 0.2 0.049 14.0 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP58120.1 - 0.00063 18.7 0.1 0.00072 18.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAP58120.1 - 0.00075 18.5 0.8 0.012 14.6 0.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.13 OAP58120.1 - 0.0014 18.3 0.3 0.002 17.8 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 OAP58120.1 - 0.0014 17.5 0.0 0.0062 15.4 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 OAP58120.1 - 0.0018 18.1 1.3 0.0048 16.8 0.9 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP58120.1 - 0.017 14.2 1.4 0.031 13.3 1.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAP58120.1 - 0.018 14.7 0.4 0.028 14.1 0.3 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.19 OAP58120.1 - 0.023 13.7 1.6 0.74 8.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 OAP58120.1 - 0.044 13.3 0.3 0.071 12.6 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 OAP58120.1 - 0.086 11.9 0.5 0.14 11.2 0.3 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 OAP58120.1 - 0.17 11.6 0.4 6.5 6.5 0.1 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4014 PF13198.1 OAP58122.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.3 1 1 0 2 2 2 0 Protein of unknown function (DUF4014) Fig1 PF12351.3 OAP58123.1 - 5.3e-10 39.4 0.9 8.6e-10 38.7 0.6 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 FA_desaturase PF00487.19 OAP58123.1 - 0.13 11.6 0.6 0.24 10.7 0.4 1.5 1 0 0 1 1 1 0 Fatty acid desaturase SUR7 PF06687.7 OAP58124.1 - 7e-22 78.0 12.7 8.5e-22 77.7 8.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family NS3_envE PF02723.9 OAP58124.1 - 1.4 8.8 6.1 0.39 10.6 0.1 2.5 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Fig1 PF12351.3 OAP58124.1 - 4.4 7.1 18.8 4.1 7.2 10.7 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 BAF1_ABF1 PF04684.8 OAP58126.1 - 0.71 8.6 8.4 1.1 8.0 5.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RLL PF10036.4 OAP58126.1 - 3.9 6.8 12.0 0.078 12.3 3.5 1.7 2 1 0 2 2 2 0 Putative carnitine deficiency-associated protein Sugar_tr PF00083.19 OAP58128.1 - 2.2e-79 267.1 28.0 2.7e-79 266.8 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58128.1 - 3e-30 105.1 25.9 6e-28 97.5 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM_3 PF13706.1 OAP58128.1 - 0.2 11.1 5.7 0.41 10.1 1.2 3.1 2 0 0 2 2 2 0 PepSY-associated TM helix DUF1700 PF08006.6 OAP58128.1 - 3.6 6.8 8.3 11 5.2 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) His_Phos_2 PF00328.17 OAP58129.1 - 6.9e-06 25.6 0.0 0.0035 16.7 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Aldedh PF00171.17 OAP58130.1 - 8.6e-154 512.2 0.2 9.7e-154 512.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 OAP58130.1 - 0.0032 16.7 0.0 0.0096 15.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) FMN_dh PF01070.13 OAP58131.1 - 1.5e-101 339.8 0.0 1.7e-101 339.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 OAP58131.1 - 0.00018 20.5 0.2 0.00037 19.5 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAP58131.1 - 0.0013 17.6 0.4 0.003 16.5 0.2 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Flag1_repress PF03614.8 OAP58131.1 - 0.034 13.7 0.1 0.42 10.1 0.1 2.1 2 0 0 2 2 2 0 Repressor of phase-1 flagellin His_biosynth PF00977.16 OAP58131.1 - 0.056 12.6 0.4 3.2 6.9 0.0 2.4 1 1 1 2 2 2 0 Histidine biosynthesis protein NMO PF03060.10 OAP58131.1 - 0.19 10.8 1.1 0.31 10.1 0.8 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Pkinase PF00069.20 OAP58132.1 - 2.1e-60 204.0 0.0 2.6e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58132.1 - 2.9e-36 124.8 0.0 4.1e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP58132.1 - 3.5e-09 36.0 0.0 5.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like KH_1 PF00013.24 OAP58133.1 - 1.6e-39 133.2 9.9 3.4e-15 55.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 OAP58133.1 - 8.1e-30 101.9 12.3 6e-12 44.9 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 OAP58133.1 - 6.4e-10 38.4 11.0 0.0079 15.7 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 OAP58133.1 - 1.8e-08 33.8 7.0 0.029 13.9 0.0 3.3 3 0 0 3 3 3 3 KH domain dUTPase PF00692.14 OAP58133.1 - 0.0026 17.2 0.1 0.43 10.0 0.0 3.0 3 0 0 3 3 3 1 dUTPase KH_5 PF13184.1 OAP58133.1 - 0.0031 17.2 5.3 0.87 9.4 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain ADH_N PF08240.7 OAP58134.1 - 6.8e-30 103.0 0.7 1e-29 102.4 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP58134.1 - 1.7e-16 59.9 0.0 2.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 OAP58134.1 - 0.016 14.8 1.1 0.035 13.7 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Yippee-Mis18 PF03226.9 OAP58135.1 - 4.9e-24 84.2 0.7 5.5e-24 84.0 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 OAP58135.1 - 0.002 18.0 2.3 0.0036 17.1 1.6 1.4 1 1 0 1 1 1 1 C-terminal domain of RIG-I SH2_2 PF14633.1 OAP58135.1 - 0.0048 15.9 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 SH2 domain HNH_5 PF14279.1 OAP58135.1 - 0.016 15.1 1.4 1.3 9.1 0.1 2.2 1 1 1 2 2 2 0 HNH endonuclease Evr1_Alr PF04777.8 OAP58135.1 - 0.039 13.8 1.3 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DUF2039 PF10217.4 OAP58135.1 - 0.041 13.8 1.8 0.069 13.1 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Eapp_C PF10238.4 OAP58135.1 - 0.056 13.3 2.4 1.6 8.6 0.3 2.2 1 1 1 2 2 2 0 E2F-associated phosphoprotein Endonuclease_7 PF02945.10 OAP58135.1 - 0.18 11.5 1.1 0.53 10.0 0.7 1.9 1 1 0 1 1 1 0 Recombination endonuclease VII Elf1 PF05129.8 OAP58135.1 - 0.18 11.5 1.6 1.3 8.8 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RabGAP-TBC PF00566.13 OAP58137.1 - 9.8e-36 123.2 0.1 1.6e-35 122.5 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Retrotrans_gag PF03732.12 OAP58137.1 - 0.045 13.8 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Pkinase PF00069.20 OAP58138.1 - 5.8e-57 192.7 0.0 8.3e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58138.1 - 9.1e-19 67.5 0.0 1.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP58138.1 - 2.7e-07 29.8 0.0 4.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAP58138.1 - 8e-06 25.7 0.3 0.0056 16.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 OAP58138.1 - 0.00013 21.0 0.1 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 OAP58138.1 - 0.0021 17.4 0.0 0.0059 15.9 0.0 1.7 1 0 0 1 1 1 1 RIO1 family LRR_6 PF13516.1 OAP58139.1 - 2.9e-13 48.3 12.0 0.065 13.3 0.0 8.1 8 0 0 8 8 8 3 Leucine Rich repeat F-box-like PF12937.2 OAP58139.1 - 1.7e-10 40.4 0.2 3.5e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 OAP58139.1 - 4.7e-07 29.2 7.5 0.002 17.6 0.0 5.4 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.28 OAP58139.1 - 7.2e-06 25.5 0.1 2.4e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 OAP58139.1 - 0.002 17.9 17.3 1.4 9.2 0.0 7.1 7 1 0 7 7 7 2 Leucine Rich Repeat PRANC PF09372.5 OAP58139.1 - 0.0028 17.5 0.0 0.0099 15.8 0.0 1.9 1 0 0 1 1 1 1 PRANC domain LRR_7 PF13504.1 OAP58139.1 - 0.37 11.1 12.9 5.1 7.7 0.1 7.0 8 0 0 8 8 8 0 Leucine rich repeat DUF4557 PF15101.1 OAP58140.1 - 0.098 12.4 7.1 0.13 12.0 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ring_hydroxyl_A PF00848.14 OAP58141.1 - 2.1e-33 115.7 2.7 4.8e-33 114.5 1.1 2.1 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) MBOAT PF03062.14 OAP58141.1 - 6.7e-32 110.8 18.0 1.6e-31 109.6 12.3 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Rieske PF00355.21 OAP58141.1 - 5.8e-14 51.4 0.0 1.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain dCMP_cyt_deam_1 PF00383.17 OAP58142.1 - 7.7e-09 35.1 0.1 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region CMS1 PF14617.1 OAP58143.1 - 6.4e-54 182.6 0.0 7.5e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 OAP58143.1 - 0.00093 18.7 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase adh_short_C2 PF13561.1 OAP58144.1 - 6.7e-19 68.6 0.0 7.7e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP58144.1 - 1.6e-13 50.9 2.4 2e-13 50.6 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAP58144.1 - 3.7e-05 23.7 0.4 6.1e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAP58144.1 - 0.00017 21.3 0.5 0.00021 21.0 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 OAP58144.1 - 0.00063 19.9 0.1 0.0015 18.7 0.0 1.6 2 0 0 2 2 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 OAP58144.1 - 0.0054 16.3 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 OAP58144.1 - 0.0076 15.2 0.2 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox PF00070.22 OAP58144.1 - 0.012 15.9 0.2 0.027 14.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.14 OAP58144.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_3 PF13738.1 OAP58144.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAP58144.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 OAP58144.1 - 0.057 12.9 0.9 0.077 12.5 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Eno-Rase_NADH_b PF12242.3 OAP58144.1 - 0.063 13.0 0.4 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Oxidored_nitro PF00148.14 OAP58144.1 - 0.085 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Methyltransf_18 PF12847.2 OAP58144.1 - 0.11 13.1 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Fumble PF03630.9 OAP58145.1 - 5.1e-133 443.1 0.8 6.4e-132 439.5 0.6 1.9 1 1 0 1 1 1 1 Fumble Nuc_sug_transp PF04142.10 OAP58147.1 - 4.3e-08 32.5 3.1 8.2e-08 31.6 2.2 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 OAP58147.1 - 1.3e-07 30.8 9.3 2.3e-07 30.0 6.5 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 OAP58147.1 - 2.9e-07 30.5 28.1 6.8e-05 22.9 4.1 3.2 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 OAP58147.1 - 0.00093 19.3 3.7 0.00093 19.3 2.5 3.5 4 0 0 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 OAP58147.1 - 0.056 13.0 23.2 0.2 11.3 1.6 2.7 3 1 0 3 3 3 0 Triose-phosphate Transporter family p450 PF00067.17 OAP58149.1 - 4e-60 203.6 0.0 5.2e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adaptin_N PF01602.15 OAP58150.1 - 1.2e-141 472.6 2.8 1.5e-141 472.3 1.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 OAP58150.1 - 3.5e-20 72.4 0.0 7.9e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 OAP58150.1 - 1.8e-07 31.3 2.2 0.068 13.4 0.0 4.7 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 OAP58150.1 - 0.0011 18.8 0.9 13 6.2 0.0 5.0 4 1 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 OAP58150.1 - 0.0034 17.2 2.0 0.022 14.6 0.3 2.9 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 OAP58150.1 - 0.0056 17.1 1.5 11 6.6 0.1 5.4 5 2 1 6 6 6 1 HEAT-like repeat Arm PF00514.18 OAP58150.1 - 0.02 14.7 0.6 61 3.6 0.0 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 OAP58150.1 - 0.043 13.4 2.6 0.06 12.9 0.0 2.5 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) DEAD PF00270.24 OAP58151.1 - 3.9e-39 133.8 0.0 5.9e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP58151.1 - 6.1e-27 93.3 0.1 1.3e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAP58151.1 - 0.00013 20.9 0.0 0.00016 20.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 OAP58151.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_transf_28 PF03033.15 OAP58152.1 - 1.3e-24 86.5 0.0 3.2e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 OAP58152.1 - 0.0017 17.0 0.0 0.0026 16.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 OAP58152.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Aldo_ket_red PF00248.16 OAP58153.1 - 3.2e-51 173.8 0.0 3.6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 OAP58154.1 - 1.1e-67 228.6 0.0 1.5e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SAF PF08666.7 OAP58155.1 - 8.2e-08 32.5 0.2 2.4e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 SAF domain NAD_binding_3 PF03447.11 OAP58155.1 - 8.6e-06 26.1 0.1 2.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.8 OAP58156.1 - 1.1e-27 96.7 0.0 4.1e-27 94.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 OAP58156.1 - 4.1e-06 26.9 0.0 5.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 OAP58156.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 OAP58156.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans_2 PF11951.3 OAP58157.1 - 6.8e-19 67.7 2.2 1.3e-18 66.7 1.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP58158.1 - 1.1e-37 129.5 33.1 1.5e-37 129.1 23.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PT-VENN PF04829.8 OAP58158.1 - 0.027 13.9 1.7 0.066 12.7 1.2 1.6 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Abhydrolase_1 PF00561.15 OAP58159.1 - 3.7e-13 49.5 0.3 9.6e-13 48.2 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP58159.1 - 1.9e-12 47.5 0.1 2.6e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP58159.1 - 0.0047 16.7 0.0 0.0097 15.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DAO PF01266.19 OAP58160.1 - 1.3e-17 63.7 0.0 1.7e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP58160.1 - 0.017 15.1 0.1 0.063 13.3 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP58160.1 - 0.035 13.8 0.4 0.086 12.6 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mqo PF06039.10 OAP58160.1 - 0.051 11.7 0.0 0.071 11.2 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 OAP58160.1 - 0.06 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 OAP58160.1 - 0.065 13.6 0.3 8.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3425 PF11905.3 OAP58161.1 - 8.4e-12 45.1 0.2 2.6e-11 43.5 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) DUF390 PF04094.9 OAP58161.1 - 0.36 8.8 5.1 1.1 7.2 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF390) bZIP_1 PF00170.16 OAP58161.1 - 6.3 6.8 11.6 13 5.8 8.0 1.6 1 0 0 1 1 1 0 bZIP transcription factor Epimerase PF01370.16 OAP58163.1 - 1.9e-09 37.3 0.1 2.8e-08 33.5 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP58163.1 - 6e-08 32.8 0.0 8.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP58163.1 - 1.5e-06 27.6 0.1 2.3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 OAP58163.1 - 2.4e-05 23.2 0.0 0.00065 18.4 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 OAP58163.1 - 0.00093 19.1 0.2 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 OAP58163.1 - 0.016 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 OAP58163.1 - 0.032 14.3 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 OAP58163.1 - 0.036 13.8 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 OAP58163.1 - 0.047 13.3 0.1 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 OAP58163.1 - 0.08 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 OAP58163.1 - 0.086 11.8 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase BCDHK_Adom3 PF10436.4 OAP58164.1 - 4.1e-42 143.4 0.0 5.8e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAP58164.1 - 1.6e-15 56.7 0.0 2.9e-14 52.7 0.0 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAP58164.1 - 0.047 13.3 0.1 0.73 9.4 0.0 2.2 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carboxyl_trans PF01039.17 OAP58165.1 - 1.9e-68 230.9 0.0 3.5e-68 230.1 0.0 1.4 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 OAP58166.1 - 1.6e-52 177.8 0.0 3e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 OAP58166.1 - 4.2e-34 116.7 0.0 1.2e-33 115.2 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 OAP58166.1 - 3.3e-23 81.8 0.0 7.1e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 OAP58166.1 - 1.1e-13 51.3 0.1 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 OAP58166.1 - 1.7e-13 49.9 2.8 7.4e-13 47.9 1.3 2.6 2 1 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 OAP58166.1 - 1.6e-11 43.5 0.0 5.6e-06 25.3 0.0 2.6 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 OAP58166.1 - 2.1e-07 30.4 0.1 3.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAP58166.1 - 6.3e-07 28.9 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 OAP58166.1 - 1.1e-06 28.1 1.7 0.0011 18.5 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like DUF2118 PF09891.4 OAP58166.1 - 0.00018 21.2 0.1 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.1 OAP58166.1 - 0.00026 20.6 0.0 0.001 18.7 0.0 2.0 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.9 OAP58166.1 - 0.0013 18.6 0.0 0.0028 17.5 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.1 OAP58166.1 - 0.012 14.7 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RimK PF08443.6 OAP58166.1 - 0.016 14.6 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain HlyD_2 PF12700.2 OAP58166.1 - 0.046 12.8 0.6 0.77 8.8 0.0 1.9 1 1 1 2 2 2 0 HlyD family secretion protein HlyD PF00529.15 OAP58166.1 - 0.16 11.2 4.2 1.8 7.7 0.4 2.2 1 1 1 2 2 2 0 HlyD family secretion protein HMG_box PF00505.14 OAP58167.1 - 2.3e-22 79.0 0.1 4e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAP58167.1 - 2.6e-09 37.3 0.0 5.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain WD40 PF00400.27 OAP58168.1 - 1.4e-77 253.0 23.9 2e-12 46.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAP58168.1 - 7.3e-08 30.9 2.4 0.00018 19.7 0.1 4.0 5 1 0 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAP58168.1 - 2.3e-06 26.6 0.1 0.68 8.6 0.0 3.5 2 1 2 4 4 4 3 Nup133 N terminal like bZIP_2 PF07716.10 OAP58168.1 - 0.0065 16.2 0.4 0.013 15.3 0.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.10 OAP58168.1 - 0.19 11.2 0.2 0.32 10.4 0.1 1.3 1 0 0 1 1 1 0 Septum formation initiator CLASP_N PF12348.3 OAP58169.1 - 3.2e-05 23.4 0.2 0.0043 16.4 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HALZ PF02183.13 OAP58169.1 - 5.5e-05 22.8 7.3 0.14 11.8 0.0 3.6 2 1 1 3 3 3 2 Homeobox associated leucine zipper Adaptin_N PF01602.15 OAP58169.1 - 0.00032 19.1 3.4 0.0032 15.8 2.3 2.4 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 OAP58169.1 - 0.00071 19.4 1.1 11 6.3 0.2 5.1 5 0 0 5 5 5 0 HEAT repeat HlyD PF00529.15 OAP58169.1 - 0.0044 16.3 6.7 0.011 15.0 4.6 1.7 1 0 0 1 1 1 1 HlyD family secretion protein TPR_MLP1_2 PF07926.7 OAP58169.1 - 0.0051 16.5 2.8 0.0051 16.5 2.0 2.6 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein DivIC PF04977.10 OAP58169.1 - 0.006 16.0 14.4 0.085 12.3 3.3 3.3 2 1 1 3 3 3 2 Septum formation initiator Cnd3 PF12719.2 OAP58169.1 - 0.036 13.0 0.3 0.45 9.4 0.0 2.5 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Vac14_Fab1_bd PF12755.2 OAP58169.1 - 0.094 13.1 0.0 45 4.5 0.0 3.5 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region TBPIP PF07106.8 OAP58169.1 - 0.099 12.1 6.2 0.4 10.2 4.3 2.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 OAP58169.1 - 0.11 11.6 8.8 0.33 10.1 6.1 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.1 OAP58169.1 - 0.28 11.1 13.2 1.8 8.5 7.7 3.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.16 OAP58169.1 - 0.37 10.7 16.0 0.4 10.6 0.6 3.4 3 0 0 3 3 3 0 bZIP transcription factor IncA PF04156.9 OAP58169.1 - 0.52 9.8 16.6 0.042 13.4 7.5 2.1 2 0 0 2 2 2 0 IncA protein ADIP PF11559.3 OAP58169.1 - 1.3 8.9 11.7 4.9 7.0 8.0 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 OAP58169.1 - 1.4 7.9 12.4 0.18 10.7 5.6 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 OAP58169.1 - 1.6 8.5 12.3 1.4 8.7 5.3 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MAP65_ASE1 PF03999.7 OAP58169.1 - 3.3 6.1 15.3 0.036 12.6 5.0 1.7 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Mod_r PF07200.8 OAP58169.1 - 8.6 6.2 13.3 0.37 10.7 4.4 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ribosomal_L7Ae PF01248.21 OAP58170.1 - 7.2e-21 73.5 0.6 7.2e-21 73.5 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HECT PF00632.20 OAP58171.1 - 9.8e-93 310.7 0.0 2.1e-92 309.6 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 OAP58171.1 - 1.2e-83 281.0 0.0 1.2e-83 281.0 0.0 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 OAP58171.1 - 1.1e-52 179.4 0.1 1.1e-52 179.4 0.1 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 OAP58171.1 - 3.8e-26 91.1 6.7 3.8e-26 91.1 4.7 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4414) DUF2585 PF10755.4 OAP58171.1 - 1 8.7 0.0 2 7.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) An_peroxidase PF03098.10 OAP58172.1 - 4.6e-91 305.7 0.0 6.3e-89 298.7 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase Imm24 PF15570.1 OAP58172.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 24 Steroid_dh PF02544.11 OAP58173.1 - 6.4e-32 110.4 0.3 8.9e-32 109.9 0.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 OAP58173.1 - 1.2e-05 25.3 0.2 2.3e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 OAP58173.1 - 0.015 14.6 0.1 0.023 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF621 PF04789.10 OAP58173.1 - 0.032 13.2 0.2 0.056 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Glyco_transf_34 PF05637.7 OAP58174.1 - 2.4e-56 190.9 0.0 3.4e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Peptidase_M20 PF01546.23 OAP58175.1 - 8.3e-25 87.3 0.1 1.2e-24 86.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 OAP58175.1 - 0.0003 20.5 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 OAP58175.1 - 0.00045 19.9 0.0 0.0012 18.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain SET PF00856.23 OAP58176.1 - 0.0029 17.9 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 SET domain Complex1_51K PF01512.12 OAP58177.1 - 3.4e-45 153.4 0.0 5.4e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 OAP58177.1 - 1.2e-18 65.9 2.0 2.5e-18 64.9 1.4 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 OAP58177.1 - 9.7e-10 38.2 0.0 5.2e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 SLBB domain AP_endonuc_2 PF01261.19 OAP58178.1 - 2.9e-25 88.7 0.2 5.7e-25 87.8 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF1838 PF08894.6 OAP58178.1 - 0.017 14.3 0.4 1 8.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1838) Tail_P2_I PF09684.5 OAP58178.1 - 0.41 10.1 2.4 0.38 10.3 0.1 2.1 3 0 0 3 3 3 0 Phage tail protein (Tail_P2_I) Inositol_P PF00459.20 OAP58179.1 - 5e-73 245.7 0.0 1e-72 244.6 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.14 OAP58180.1 - 3.3e-52 175.5 0.0 1.2e-30 105.7 0.0 2.0 2 0 0 2 2 2 2 Dehydroquinase class II Sugar_tr PF00083.19 OAP58181.1 - 3.6e-125 418.0 27.3 4.1e-125 417.8 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58181.1 - 5.2e-20 71.4 35.7 5.2e-20 71.4 24.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.6 OAP58182.1 - 1.3e-21 76.3 0.0 2.3e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 OAP58182.1 - 8.7e-12 45.2 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DHquinase_I PF01487.10 OAP58183.1 - 4.5e-30 104.9 0.0 7.2e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 OAP58183.1 - 8.9e-16 58.1 0.2 2.3e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 OAP58183.1 - 1.8e-15 56.7 0.0 4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 OAP58183.1 - 1.3e-11 44.7 0.0 2.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 OAP58183.1 - 0.08 13.3 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 OAP58183.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 ThiF family TTKRSYEDQ PF10212.4 OAP58183.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Fungal_trans PF04082.13 OAP58184.1 - 3.5e-18 65.3 0.0 5.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58184.1 - 2e-08 34.0 11.9 3.5e-08 33.2 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 OAP58185.1 - 1.4e-23 83.5 0.0 2.3e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 OAP58186.1 - 4.6e-06 26.2 0.0 1.5e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 OAP58186.1 - 0.002 18.0 2.4 2.6 8.3 0.0 5.3 7 0 0 7 7 7 1 Leucine Rich repeat F-box PF00646.28 OAP58186.1 - 0.0053 16.3 0.4 0.033 13.8 0.3 2.4 1 1 0 1 1 1 1 F-box domain MinE PF03776.9 OAP58186.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE LRR_4 PF12799.2 OAP58186.1 - 0.16 11.6 10.3 3 7.5 0.1 4.1 3 3 1 4 4 4 0 Leucine Rich repeats (2 copies) Aminotran_5 PF00266.14 OAP58187.1 - 1.9e-22 79.5 0.0 8.7e-22 77.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAP58187.1 - 3.2e-05 23.0 0.0 0.00011 21.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II AIRS PF00586.19 OAP58187.1 - 0.025 14.8 0.1 0.42 10.8 0.0 2.4 1 1 1 2 2 2 0 AIR synthase related protein, N-terminal domain SLA_LP_auto_ag PF05889.8 OAP58187.1 - 0.036 12.5 0.0 0.055 11.9 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) ADH_zinc_N PF00107.21 OAP58188.1 - 1.2e-23 83.0 0.4 2e-23 82.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP58188.1 - 3.2e-11 44.2 0.1 7.3e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP58188.1 - 2.4e-09 36.9 0.0 7e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CAAP1 PF15335.1 OAP58188.1 - 0.18 12.0 0.2 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 SPATIAL PF15256.1 OAP58191.1 - 7.3 6.5 11.8 1.8 8.5 4.7 2.6 3 1 0 3 3 3 0 SPATIAL ADH_zinc_N PF00107.21 OAP58192.1 - 5.7e-09 35.6 0.1 1.4e-08 34.3 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP58192.1 - 7.7e-07 28.8 0.0 4.9e-05 23.0 0.0 2.7 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP58192.1 - 0.0021 18.9 0.7 0.21 12.4 0.1 3.3 2 1 1 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.20 OAP58192.1 - 0.0022 17.9 0.2 0.0042 17.0 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.11 OAP58193.1 - 0.00062 18.5 10.3 0.0043 15.8 1.4 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Pribosyltran_N PF13793.1 OAP58194.1 - 2.4e-43 146.5 0.2 6.9e-43 145.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAP58194.1 - 6.7e-34 117.2 0.6 6.3e-28 97.7 0.3 2.6 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAP58194.1 - 2.8e-12 46.4 0.3 5.9e-11 42.1 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAP58194.1 - 0.0017 17.6 0.2 0.0033 16.6 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chorismate_bind PF00425.13 OAP58195.1 - 7.8e-86 287.5 0.0 1.1e-85 287.0 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Ribosomal_S6e PF01092.14 OAP58195.1 - 6.3e-62 206.8 0.2 1.2e-61 205.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Anth_synt_I_N PF04715.8 OAP58195.1 - 8e-28 97.1 0.0 1.2e-25 90.0 0.0 3.2 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Stk19 PF10494.4 OAP58195.1 - 0.061 12.7 0.1 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 GST_C_3 PF14497.1 OAP58196.1 - 0.088 13.2 0.1 0.37 11.2 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF4055 PF13264.1 OAP58196.1 - 0.15 12.1 6.5 0.26 11.3 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) DivIC PF04977.10 OAP58196.1 - 0.34 10.4 5.7 0.28 10.7 2.5 1.9 1 1 0 1 1 1 0 Septum formation initiator BLOC1_2 PF10046.4 OAP58196.1 - 0.75 9.9 6.4 0.12 12.4 1.5 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nop25 PF09805.4 OAP58196.1 - 0.76 9.8 9.4 1.2 9.1 0.3 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) V_ATPase_I PF01496.14 OAP58196.1 - 1.1 7.0 4.8 0.15 9.8 0.7 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.11 OAP58196.1 - 1.4 6.9 9.6 3.7 5.6 6.7 1.6 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF904 PF06005.7 OAP58196.1 - 1.8 8.9 12.9 1.6 9.0 3.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 OAP58196.1 - 3.4 7.5 18.7 1.1 9.0 4.4 2.8 2 1 1 3 3 3 0 Tropomyosin like Mnd1 PF03962.10 OAP58196.1 - 4.5 6.8 12.0 2.6 7.6 0.3 2.2 1 1 1 2 2 2 0 Mnd1 family DUF972 PF06156.8 OAP58196.1 - 6.2 7.2 13.9 0.24 11.7 3.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF972) WD40 PF00400.27 OAP58197.1 - 5.4e-14 51.4 0.9 0.0051 16.6 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat LisH PF08513.6 OAP58197.1 - 1.9e-08 33.7 0.1 6.7e-08 32.0 0.1 2.0 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 OAP58197.1 - 0.00097 18.9 0.0 0.026 14.2 0.0 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A YmzC PF14157.1 OAP58197.1 - 0.012 15.4 0.0 0.065 13.0 0.0 2.1 2 0 0 2 2 2 0 YmzC-like protein DUF1751 PF08551.5 OAP58198.1 - 9.9e-24 83.5 2.6 2.1e-23 82.4 1.8 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 OAP58198.1 - 2.4e-05 24.4 6.5 4.8e-05 23.4 4.5 1.5 1 0 0 1 1 1 1 Rhomboid family Ribonuclease_T2 PF00445.13 OAP58199.1 - 1.4e-30 106.3 0.1 2.1e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family ABM PF03992.11 OAP58200.1 - 0.028 14.4 0.3 2.4 8.2 0.0 2.5 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase ENTH PF01417.15 OAP58201.1 - 6.8e-49 164.8 0.0 1e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 OAP58201.1 - 0.00026 19.7 0.0 0.00038 19.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 OAP58201.1 - 0.011 15.0 0.1 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) GPI-anchored PF10342.4 OAP58202.1 - 2.8e-08 34.1 3.0 2.8e-08 34.1 2.1 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Clr5 PF14420.1 OAP58203.1 - 2.8e-08 33.5 0.4 6.2e-08 32.4 0.3 1.6 1 0 0 1 1 1 1 Clr5 domain Clr5 PF14420.1 OAP58204.1 - 7.6e-11 41.7 0.3 1.5e-10 40.7 0.2 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 OAP58204.1 - 0.0097 15.8 0.0 0.33 10.9 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP58204.1 - 0.067 13.1 1.2 7.3 6.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Complex1_LYR_2 PF13233.1 OAP58205.1 - 3.4e-19 69.2 0.1 4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like NAD_binding_2 PF03446.10 OAP58206.1 - 6.1e-26 91.1 0.3 9.6e-26 90.5 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP58206.1 - 2.6e-20 72.6 0.0 4.8e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F-box-like PF12937.2 OAP58207.1 - 0.0061 16.2 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP58207.1 - 0.047 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain DUF1604 PF07713.8 OAP58207.1 - 0.097 12.4 1.2 1.5 8.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) MutL_C PF08676.6 OAP58208.1 - 1.4e-23 83.0 0.0 3.6e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 OAP58208.1 - 9.1e-21 73.5 0.0 9.1e-20 70.3 0.0 2.7 4 0 0 4 4 4 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 OAP58208.1 - 5.8e-13 48.6 0.6 2e-12 46.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAP58208.1 - 2.5e-11 43.2 0.1 7.4e-11 41.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carn_acyltransf PF00755.15 OAP58209.1 - 2.2e-173 577.5 0.1 2.6e-173 577.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2034 PF10356.4 OAP58210.1 - 5.2e-27 94.1 0.0 2.3e-22 79.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 OAP58210.1 - 5.6e-07 29.3 0.1 0.00022 21.0 0.0 2.9 2 1 0 2 2 2 1 Restriction endonuclease DUF3237 PF11578.3 OAP58211.1 - 8.5e-14 51.1 0.0 1.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Glyco_hydro_2 PF00703.16 OAP58214.1 - 1.1e-09 38.7 0.0 2.3e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 OAP58214.1 - 5.7e-06 25.9 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 OAP58214.1 - 0.00022 20.2 0.0 0.0004 19.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain MFS_1 PF07690.11 OAP58215.1 - 3.3e-25 88.5 35.3 5.2e-25 87.9 24.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cytidylate_kin PF02224.13 OAP58215.1 - 0.029 13.8 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Peptidase_S9_N PF02897.10 OAP58216.1 - 1.2e-43 149.2 0.0 1.7e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 OAP58216.1 - 3.4e-35 121.2 0.0 5.3e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP58216.1 - 3.5e-09 36.5 0.1 7.8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP58216.1 - 2.5e-06 27.5 2.0 5.8e-06 26.3 0.4 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP58216.1 - 7.1e-05 22.4 0.9 0.0002 21.0 0.6 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 OAP58216.1 - 0.025 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF3172 PF11371.3 OAP58216.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Ribosomal_S7 PF00177.16 OAP58217.1 - 3.3e-28 98.1 0.0 5.7e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Na_Ca_ex PF01699.19 OAP58218.1 - 6.5e-47 158.6 31.0 1.6e-24 86.1 8.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Dynactin PF12455.3 OAP58219.1 - 3.3e-57 193.4 7.1 3.3e-57 193.4 4.9 4.2 6 0 0 6 6 6 1 Dynein associated protein CAP_GLY PF01302.20 OAP58219.1 - 3.1e-21 74.8 0.3 6e-21 73.9 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain KH_1 PF00013.24 OAP58220.1 - 4.5e-32 109.4 7.7 1.1e-07 31.4 0.2 7.4 7 0 0 7 7 7 7 KH domain KH_3 PF13014.1 OAP58220.1 - 7.9e-24 82.8 6.4 0.00025 20.6 0.0 6.7 6 0 0 6 6 6 5 KH domain SUV3_C PF12513.3 OAP58220.1 - 0.09 12.2 0.0 0.25 10.7 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal DUF4210 PF13915.1 OAP58221.1 - 6.9e-26 90.3 0.1 1.5e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 OAP58221.1 - 1.4e-22 79.2 0.7 5.1e-22 77.5 0.1 2.3 2 0 0 2 2 2 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 OAP58222.1 - 0.011 15.5 4.2 0.011 15.5 2.9 2.2 1 1 1 2 2 2 0 rRNA processing RNA_pol_Rpc4 PF05132.9 OAP58222.1 - 2.4 8.1 10.4 11 5.9 3.0 2.2 1 1 1 2 2 2 0 RNA polymerase III RPC4 Actin PF00022.14 OAP58223.1 - 7.6e-126 419.6 0.0 8.6e-126 419.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAP58223.1 - 0.11 11.1 0.0 5.8 5.4 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Methyltransf_23 PF13489.1 OAP58224.1 - 1.2e-14 54.4 0.0 2.9e-14 53.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP58224.1 - 2e-06 27.4 0.0 8.6e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP58224.1 - 0.00048 20.5 0.0 0.00097 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP58224.1 - 0.00064 20.2 0.0 0.0024 18.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP58224.1 - 0.0076 16.7 0.0 0.039 14.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP58224.1 - 0.046 13.7 0.0 0.07 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAP58224.1 - 0.055 13.8 0.0 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 OAP58224.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 OAP58224.1 - 0.067 12.5 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Rax2 PF12768.2 OAP58225.1 - 8.1e-84 281.1 13.7 3.7e-78 262.5 0.0 5.6 4 2 1 6 6 6 5 Cortical protein marker for cell polarity OGG_N PF07934.7 OAP58226.1 - 6.1e-31 106.8 0.0 1.3e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 OAP58226.1 - 6e-17 61.8 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAP58226.1 - 0.0098 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif AA_permease_2 PF13520.1 OAP58227.1 - 4.5e-46 157.2 47.0 5.3e-46 157.0 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease MT PF12777.2 OAP58227.1 - 0.64 8.7 1.2 0.7 8.5 0.1 1.5 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor Fungal_trans_2 PF11951.3 OAP58228.1 - 1.1e-35 123.0 1.0 2.6e-35 121.7 0.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58228.1 - 3.5e-05 23.6 7.9 6.6e-05 22.7 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP58228.1 - 0.0056 15.5 0.1 0.0099 14.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M20 PF01546.23 OAP58229.1 - 4e-25 88.4 0.0 6e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAP58229.1 - 1.7e-12 47.0 0.0 3.7e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain RRM_1 PF00076.17 OAP58230.1 - 3.9e-33 112.9 0.0 8.1e-14 51.0 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP58230.1 - 6.3e-23 80.5 0.0 5.9e-08 32.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP58230.1 - 8.2e-18 64.0 0.0 1.1e-06 28.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 OAP58230.1 - 0.0018 18.2 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 2 Smg-4/UPF3 family Nup35_RRM_2 PF14605.1 OAP58230.1 - 0.011 15.4 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 OAP58230.1 - 0.016 14.9 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SKG6 PF08693.5 OAP58230.1 - 0.38 10.1 4.6 1 8.7 3.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GTP_EFTU PF00009.22 OAP58231.1 - 4.2e-43 146.9 0.0 6.6e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAP58231.1 - 1.9e-20 72.8 0.1 6.3e-20 71.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 OAP58231.1 - 1.5e-05 24.9 0.0 4.1e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 OAP58231.1 - 9.4e-05 22.4 0.1 0.00022 21.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 G-alpha PF00503.15 OAP58231.1 - 0.0075 15.0 0.5 0.014 14.0 0.3 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Ran-binding PF05508.6 OAP58232.1 - 2.5e-115 384.5 0.2 3.1e-115 384.2 0.2 1.1 1 0 0 1 1 1 1 RanGTP-binding protein CorA PF01544.13 OAP58232.1 - 0.074 12.0 2.7 0.14 11.1 1.8 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CSTF2_hinge PF14327.1 OAP58233.1 - 5.6e-29 100.0 2.2 5.6e-29 100.0 1.5 2.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 OAP58233.1 - 6.5e-20 70.5 0.2 1.1e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP58233.1 - 1.2e-16 60.4 0.1 2.2e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP58233.1 - 7e-10 38.6 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 OAP58233.1 - 0.0017 17.5 6.4 0.0017 17.5 4.5 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Band_7 PF01145.20 OAP58234.1 - 9.9e-24 84.2 3.2 1.5e-23 83.6 2.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 OAP58234.1 - 0.11 11.8 2.7 0.16 11.1 1.9 1.4 1 1 0 1 1 1 0 MraW methylase family SNF2_N PF00176.18 OAP58235.1 - 2.5e-21 75.7 0.1 4.8e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 OAP58235.1 - 3.6e-12 46.0 0.0 7.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase ACC_central PF08326.7 OAP58236.1 - 2.8e-259 862.0 0.0 3.5e-259 861.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 OAP58236.1 - 7.8e-179 595.1 0.0 1.3e-178 594.4 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 OAP58236.1 - 1.4e-52 178.0 0.0 2.7e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 OAP58236.1 - 2.1e-24 85.7 0.1 4.4e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAP58236.1 - 2.4e-24 85.3 0.0 2.2e-21 75.8 0.0 3.5 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 OAP58236.1 - 6.8e-16 57.6 0.2 1.5e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 OAP58236.1 - 6.5e-12 45.5 0.0 1.7e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAP58236.1 - 2.2e-09 36.4 0.0 8.8e-05 21.3 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAP58236.1 - 0.00065 19.1 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 OAP58236.1 - 0.0043 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 OAP58236.1 - 0.0095 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 OAP58236.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like DUF4440 PF14534.1 OAP58237.1 - 0.00031 20.9 0.0 0.00063 19.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 OAP58237.1 - 0.0031 17.9 0.1 0.0069 16.7 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 OAP58237.1 - 0.0048 16.8 0.1 0.0098 15.8 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain RNA_pol_Rpb2_6 PF00562.23 OAP58238.1 - 7.9e-116 386.9 0.0 1e-115 386.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAP58238.1 - 8.4e-35 119.5 0.0 1.4e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 OAP58238.1 - 3.4e-24 85.3 0.0 6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 OAP58238.1 - 4.3e-24 84.0 0.0 9.9e-24 82.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 OAP58238.1 - 3.3e-22 78.1 0.0 7.3e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 OAP58238.1 - 4.4e-15 55.6 0.0 1.2e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 OAP58238.1 - 0.00024 21.0 0.0 0.00053 19.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PseudoU_synth_1 PF01416.15 OAP58240.1 - 7.5e-21 74.5 0.0 1.8e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Catalase-rel PF06628.7 OAP58240.1 - 0.11 12.4 1.0 0.9 9.4 0.3 2.3 2 0 0 2 2 2 0 Catalase-related immune-responsive DeoC PF01791.4 OAP58241.1 - 6.8e-42 143.3 2.8 8.5e-42 143.0 2.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase MOSC PF03473.12 OAP58242.1 - 1.9e-16 59.7 0.1 1.8e-15 56.5 0.1 2.0 1 1 0 1 1 1 1 MOSC domain zf-C3HC4 PF00097.20 OAP58243.1 - 1 9.0 7.1 42 3.9 4.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.13 OAP58244.1 - 9.8e-10 38.1 11.3 1.6e-09 37.4 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 OAP58245.1 - 1.9e-25 89.6 0.0 3.2e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP58245.1 - 1.7e-21 76.3 0.0 3.7e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CMD PF02627.15 OAP58246.1 - 2.5e-09 36.8 0.1 2.1e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family Pex14_N PF04695.8 OAP58247.1 - 0.076 13.0 2.0 0.083 12.9 1.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LAMTOR PF15454.1 OAP58248.1 - 7.4e-12 45.3 0.0 1.6e-11 44.2 0.0 1.6 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator G10 PF01125.12 OAP58249.1 - 0.02 14.4 1.0 0.041 13.4 0.7 1.4 1 0 0 1 1 1 0 G10 protein AMP-binding PF00501.23 OAP58250.1 - 1.4e-54 185.0 0.0 1.8e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP58250.1 - 3.1e-11 44.0 0.0 8.7e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACOX PF01756.14 OAP58251.1 - 1e-33 116.3 0.0 2.2e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 OAP58251.1 - 2.7e-26 92.3 1.1 4.8e-26 91.4 0.3 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAP58251.1 - 8.7e-08 31.5 0.1 2.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 OAP58251.1 - 0.056 13.5 1.8 0.66 10.0 1.3 2.2 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ECH PF00378.15 OAP58252.1 - 1.3e-26 93.2 0.0 1.6e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MFS_1 PF07690.11 OAP58253.1 - 4.1e-40 137.5 51.2 4.1e-40 137.5 35.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP58253.1 - 1.1e-13 50.6 14.6 1.1e-13 50.6 10.1 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Peptidase_M24 PF00557.19 OAP58254.1 - 2.8e-51 174.0 0.0 4.4e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 OAP58254.1 - 7.2e-39 132.2 0.0 1.3e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Pyridox_ox_2 PF12900.2 OAP58255.1 - 4e-39 133.6 0.0 5.5e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cellulase PF00150.13 OAP58257.1 - 3.5e-13 49.4 0.2 7.9e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SDA1 PF05285.7 OAP58257.1 - 0.0024 17.2 11.5 0.0037 16.5 8.0 1.2 1 0 0 1 1 1 1 SDA1 DUF2946 PF11162.3 OAP58257.1 - 0.076 13.2 0.0 0.076 13.2 0.0 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2946) DUF805 PF05656.9 OAP58257.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF2427 PF10348.4 OAP58257.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF1510 PF07423.6 OAP58257.1 - 0.12 11.7 10.2 0.35 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1980 PF09323.5 OAP58257.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) APG12 PF04110.8 OAP58260.1 - 7.2e-29 99.8 0.0 9.5e-29 99.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 OAP58260.1 - 0.0037 17.2 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 OAP58261.1 - 1.3e-103 345.6 0.1 1.6e-103 345.4 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 OAP58261.1 - 7.2e-10 38.4 1.6 8.8e-09 34.9 1.1 2.1 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase YceG PF02618.11 OAP58261.1 - 0.12 11.3 0.0 0.29 10.1 0.0 1.5 2 0 0 2 2 2 0 YceG-like family UQ_con PF00179.21 OAP58262.1 - 4.5e-37 126.5 0.1 5.8e-37 126.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_E PF14462.1 OAP58262.1 - 0.14 11.7 0.2 0.3 10.6 0.1 1.6 2 0 0 2 2 2 0 Prokaryotic E2 family E RPEL PF02755.10 OAP58263.1 - 3.9e-08 32.3 2.5 0.00091 18.4 0.0 3.6 4 0 0 4 4 4 2 RPEL repeat F-box PF00646.28 OAP58263.1 - 7.1e-08 31.9 3.0 7.1e-08 31.9 2.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 OAP58263.1 - 1.1e-07 31.4 3.1 2.4e-07 30.3 2.1 1.5 1 0 0 1 1 1 1 F-box-like HemY_N PF07219.8 OAP58263.1 - 0.04 13.4 0.5 0.099 12.2 0.3 1.6 1 0 0 1 1 1 0 HemY protein N-terminus zf-C2H2_2 PF12756.2 OAP58264.1 - 1.7e-23 82.6 0.4 1.7e-23 82.6 0.3 1.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 OAP58264.1 - 0.05 13.9 10.2 0.27 11.6 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP58264.1 - 0.091 13.1 7.9 2.9 8.4 0.1 3.8 2 1 1 3 3 3 0 C2H2-type zinc finger CD34_antigen PF06365.7 OAP58265.1 - 0.19 11.3 2.3 4.3 6.9 0.1 2.5 2 0 0 2 2 2 0 CD34/Podocalyxin family PsbN PF02468.10 OAP58265.1 - 5.8 6.6 7.3 21 4.8 3.7 2.9 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) SNF2_N PF00176.18 OAP58266.1 - 2.4e-74 249.8 0.0 3.9e-74 249.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP58266.1 - 2.7e-10 39.9 0.0 6.4e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 OAP58266.1 - 0.032 13.6 0.0 0.032 13.6 0.0 2.2 2 1 1 3 3 3 0 DEAD_2 NPR3 PF03666.8 OAP58266.1 - 0.48 8.8 5.1 1.1 7.7 3.5 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.5 OAP58266.1 - 3.6 7.5 23.7 0.06 13.3 8.7 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pkinase PF00069.20 OAP58267.1 - 2.8e-61 206.9 0.0 3.8e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58267.1 - 4.1e-35 121.1 0.0 5.6e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP58267.1 - 1.3e-05 24.2 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAP58267.1 - 0.00038 20.2 1.5 0.00042 20.1 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 OAP58267.1 - 0.0026 16.8 0.2 0.0051 15.9 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dfp1_Him1_M PF08630.5 OAP58268.1 - 2.3e-32 111.4 0.2 5.8e-32 110.0 0.0 1.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 OAP58268.1 - 1.8e-25 88.3 1.3 8e-25 86.2 0.1 2.3 2 0 0 2 2 2 1 DBF zinc finger PTCB-BRCT PF12738.2 OAP58268.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF2547 PF10818.3 OAP58268.1 - 2.4 8.8 8.4 0.39 11.3 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Pkinase PF00069.20 OAP58269.1 - 2e-17 63.2 0.0 3.4e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58269.1 - 2.5e-08 33.3 0.0 6.5e-07 28.6 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L6 PF00347.18 OAP58270.1 - 3.8e-24 84.9 0.0 2.5e-12 47.1 0.0 3.1 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.20 OAP58271.1 - 1.7e-51 175.0 3.0 3.9e-51 173.9 2.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.14 OAP58272.1 - 2.8e-18 65.9 0.0 6.2e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 OAP58272.1 - 2.1e-09 37.2 0.2 6.5e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 OAP58272.1 - 0.00059 19.7 0.0 0.0032 17.3 0.0 2.1 1 1 0 1 1 1 1 ENTH domain SnoaL_2 PF12680.2 OAP58273.1 - 0.0062 16.9 0.1 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 OAP58273.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain FAD_binding_3 PF01494.14 OAP58274.1 - 1.2e-17 64.0 0.0 1.9e-08 33.7 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP58274.1 - 1.1e-07 31.0 3.1 6.5e-07 28.5 2.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP58274.1 - 4.2e-07 29.1 4.5 6.9e-07 28.4 3.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 OAP58274.1 - 1.6e-06 28.4 0.0 3.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP58274.1 - 2.5e-06 27.3 0.7 6.2e-06 26.1 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP58274.1 - 5.5e-06 26.4 0.3 9.1e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP58274.1 - 7.6e-06 24.8 0.0 5.1e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 OAP58274.1 - 1.2e-05 24.6 3.4 1.8e-05 24.0 2.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP58274.1 - 0.00025 19.6 0.2 0.00052 18.5 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 OAP58274.1 - 0.00043 19.4 0.1 0.00073 18.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 OAP58274.1 - 0.00063 18.7 0.2 0.017 14.0 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 OAP58274.1 - 0.00066 18.6 2.2 0.0011 17.9 1.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 OAP58274.1 - 0.0076 15.3 0.8 0.087 11.8 0.3 2.7 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase TrkA_N PF02254.13 OAP58274.1 - 0.039 13.9 0.1 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 OAP58274.1 - 0.044 13.3 1.0 0.11 12.0 0.7 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Smr PF01713.16 OAP58275.1 - 5e-08 33.0 0.2 1.8e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 OAP58275.1 - 4.9e-05 22.7 0.0 9.9e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain DUF1771 PF08590.5 OAP58275.1 - 0.32 11.0 9.3 0.9 9.5 6.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) SR-25 PF10500.4 OAP58275.1 - 9.3 5.6 10.4 0.26 10.7 2.8 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SelR PF01641.13 OAP58276.1 - 8.7e-52 174.0 0.2 1e-51 173.8 0.2 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 OAP58276.1 - 0.0024 17.5 0.5 0.27 10.9 0.0 2.3 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 OAP58276.1 - 0.0076 16.0 2.3 1 9.2 0.1 2.4 2 1 0 2 2 2 2 Double zinc ribbon GFA PF04828.9 OAP58276.1 - 0.0099 15.8 1.0 0.99 9.3 0.0 2.2 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 OAP58276.1 - 0.015 14.5 0.8 0.4 10.0 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 OAP58276.1 - 0.066 12.4 2.6 3 7.1 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DnaJ_CXXCXGXG PF00684.14 OAP58276.1 - 0.14 12.1 2.2 0.46 10.5 0.1 2.3 2 0 0 2 2 2 0 DnaJ central domain Yippee-Mis18 PF03226.9 OAP58276.1 - 0.21 11.6 1.2 1 9.4 0.8 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Mss51 PF13824.1 OAP58276.1 - 0.3 10.9 4.5 2.6 7.9 0.2 3.2 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2318 PF10080.4 OAP58276.1 - 0.38 10.5 1.8 8.3 6.2 0.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Zn_ribbon_recom PF13408.1 OAP58276.1 - 0.58 10.4 3.5 10 6.4 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain NOB1_Zn_bind PF08772.6 OAP58276.1 - 2.9 7.7 5.1 2.6 7.9 0.4 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like MFS_1 PF07690.11 OAP58277.1 - 9.1e-32 110.1 32.3 1.3e-31 109.6 22.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily QRPTase_C PF01729.14 OAP58278.1 - 5.4e-54 182.2 0.0 6.7e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 OAP58278.1 - 4e-22 77.8 0.0 1.1e-21 76.4 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 OAP58278.1 - 0.035 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase IGPS PF00218.16 OAP58278.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase AIRC PF00731.15 OAP58279.1 - 7.3e-56 187.6 2.5 9e-56 187.3 1.7 1.0 1 0 0 1 1 1 1 AIR carboxylase Fungal_trans PF04082.13 OAP58280.1 - 8.9e-28 96.8 4.6 1.4e-27 96.2 2.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP58280.1 - 7e-09 35.5 8.6 0.00052 20.2 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP58280.1 - 1.1e-07 31.6 13.7 4.2e-05 23.5 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP58280.1 - 5.6 7.4 16.1 1.9 8.8 2.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Abhydrolase_6 PF12697.2 OAP58281.1 - 6.1e-26 91.6 13.5 1.1e-25 90.8 9.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP58281.1 - 8.5e-12 45.0 0.3 1.9e-11 43.9 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1688 PF07958.6 OAP58282.1 - 1.8e-149 497.8 0.0 2e-149 497.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) GFO_IDH_MocA PF01408.17 OAP58283.1 - 4e-18 66.0 0.0 8.5e-18 65.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 OAP58283.1 - 0.0036 17.6 0.7 0.0092 16.3 0.3 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain HAD_2 PF13419.1 OAP58284.1 - 1.4e-16 61.2 0.0 3.2e-16 60.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Pribosyltran_N PF13793.1 OAP58285.1 - 2.3e-43 146.5 0.5 1.4e-41 140.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAP58285.1 - 1.1e-35 123.0 2.8 8.9e-31 107.0 0.5 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAP58285.1 - 5.7e-12 45.4 1.8 1.6e-11 44.0 1.3 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAP58285.1 - 0.036 13.2 1.1 0.082 12.1 0.3 1.9 2 1 0 2 2 2 0 Uracil phosphoribosyltransferase DUF218 PF02698.12 OAP58285.1 - 0.094 12.2 0.0 0.31 10.5 0.0 1.7 1 1 0 1 1 1 0 DUF218 domain AA_permease_2 PF13520.1 OAP58286.1 - 2.6e-58 197.5 25.8 1.1e-57 195.4 17.8 1.8 1 1 0 1 1 1 1 Amino acid permease Ank_2 PF12796.2 OAP58288.1 - 3.8e-44 148.9 3.8 3e-17 62.7 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 OAP58288.1 - 1.7e-40 134.8 15.9 2.9e-10 39.4 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 OAP58288.1 - 8.1e-38 128.1 6.2 9.6e-15 54.6 0.0 6.3 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP58288.1 - 3.2e-29 100.2 11.6 3.4e-10 39.8 0.1 6.4 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP58288.1 - 6.3e-22 75.4 7.7 1.9e-05 24.4 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Baculo_PEP_C PF04513.7 OAP58289.1 - 0.00029 20.6 0.2 0.00054 19.7 0.2 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Abi_C PF14355.1 OAP58289.1 - 0.00046 20.0 0.0 0.61 10.0 0.0 2.3 2 0 0 2 2 2 2 Abortive infection C-terminus DUF1664 PF07889.7 OAP58289.1 - 0.0012 18.6 0.6 0.0017 18.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF4618 PF15397.1 OAP58289.1 - 0.0028 17.0 0.2 0.0038 16.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Mnd1 PF03962.10 OAP58289.1 - 0.0029 17.3 0.4 0.0036 16.9 0.3 1.1 1 0 0 1 1 1 1 Mnd1 family WEMBL PF05701.6 OAP58289.1 - 0.0043 15.5 0.5 0.0055 15.2 0.4 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF2730 PF10805.3 OAP58289.1 - 0.012 15.2 0.7 0.065 12.9 0.8 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF2730) IFT57 PF10498.4 OAP58289.1 - 0.012 14.3 0.9 0.016 13.9 0.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1640 PF07798.6 OAP58289.1 - 0.021 14.8 0.6 0.031 14.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) SF-assemblin PF06705.6 OAP58289.1 - 0.023 13.8 0.2 0.028 13.5 0.2 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Bacillus_HBL PF05791.6 OAP58289.1 - 0.023 14.0 0.5 0.033 13.5 0.3 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Prominin PF05478.6 OAP58289.1 - 0.027 12.0 0.0 0.03 11.8 0.0 1.0 1 0 0 1 1 1 0 Prominin Reo_sigmaC PF04582.7 OAP58289.1 - 0.044 12.9 0.1 0.052 12.7 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 OAP58289.1 - 0.051 13.4 1.6 1 9.2 0.8 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Tektin PF03148.9 OAP58289.1 - 0.053 12.0 1.5 0.077 11.5 0.9 1.3 1 1 0 1 1 1 0 Tektin family EzrA PF06160.7 OAP58289.1 - 0.063 11.4 0.8 0.12 10.5 0.4 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_13 PF13166.1 OAP58289.1 - 0.076 11.4 0.8 0.094 11.1 0.6 1.1 1 0 0 1 1 1 0 AAA domain M_domain PF12938.2 OAP58289.1 - 0.094 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 M domain of GW182 Syntaxin_2 PF14523.1 OAP58289.1 - 0.12 12.4 1.7 3.8 7.5 1.2 2.4 1 1 0 1 1 1 0 Syntaxin-like protein Syntaxin PF00804.20 OAP58289.1 - 0.12 12.5 2.7 0.52 10.5 1.8 2.1 1 1 0 1 1 1 0 Syntaxin XhlA PF10779.4 OAP58289.1 - 0.13 12.1 1.3 0.21 11.5 0.9 1.3 1 0 0 1 1 1 0 Haemolysin XhlA TPR_MLP1_2 PF07926.7 OAP58289.1 - 0.15 11.7 2.2 11 5.8 0.0 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 OAP58289.1 - 0.2 11.9 1.5 4 7.7 1.0 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ArfGap PF01412.13 OAP58290.1 - 2.5e-41 140.1 0.4 3.5e-41 139.6 0.3 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf HET PF06985.6 OAP58291.1 - 1.9e-22 79.9 6.2 3.2e-19 69.4 0.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FB_lectin PF07367.6 OAP58291.1 - 3.1e-09 36.5 0.1 6e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Fungal fruit body lectin CorA PF01544.13 OAP58292.1 - 1.6e-07 30.6 0.1 2.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CcmD PF04995.9 OAP58292.1 - 0.25 11.1 2.5 0.74 9.5 1.7 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) RyR PF02026.11 OAP58293.1 - 6.6e-12 45.2 0.3 6.2e-07 29.3 0.1 2.4 2 0 0 2 2 2 2 RyR domain Torsin PF06309.6 OAP58293.1 - 0.0057 16.5 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Torsin KAP_NTPase PF07693.9 OAP58293.1 - 0.2 10.6 0.0 0.37 9.7 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Zds_C PF08632.5 OAP58294.1 - 1.1e-30 104.7 1.1 1.1e-30 104.7 0.8 1.8 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2244 PF10003.4 OAP58295.1 - 0.053 12.8 1.8 0.074 12.4 1.3 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) SNARE PF05739.14 OAP58295.1 - 0.056 13.1 0.1 0.073 12.7 0.1 1.2 1 0 0 1 1 1 0 SNARE domain DUF4349 PF14257.1 OAP58295.1 - 0.1 11.8 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) TFIIE_alpha PF02002.12 OAP58296.1 - 1.4e-11 43.8 0.0 3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit Rubredoxin PF00301.15 OAP58296.1 - 0.081 12.8 1.6 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 Rubredoxin PHD PF00628.24 OAP58296.1 - 0.12 12.0 2.1 2.1 8.0 0.5 2.6 2 0 0 2 2 2 0 PHD-finger Fungal_trans_2 PF11951.3 OAP58297.1 - 0.00011 20.9 0.2 0.00017 20.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tht1 PF04163.7 OAP58298.1 - 1.2e-06 27.2 1.1 2.3e-06 26.3 0.8 1.4 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein CENP-H PF05837.7 OAP58298.1 - 0.1 12.8 12.6 1 9.5 0.1 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) COG2 PF06148.6 OAP58298.1 - 0.13 12.0 9.6 1.7 8.5 2.0 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Sipho_Gp157 PF05565.6 OAP58298.1 - 0.25 10.9 2.4 0.47 10.0 1.7 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 Baculo_PEP_C PF04513.7 OAP58298.1 - 3.7 7.3 13.6 1.3 8.8 1.8 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.1 OAP58298.1 - 4.9 7.6 17.7 0.079 13.3 0.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Neurensin PF14927.1 OAP58300.1 - 0.003 16.9 0.2 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 Neurensin SIR2 PF02146.12 OAP58301.1 - 7.5e-38 130.0 0.0 2.9e-37 128.0 0.0 1.8 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 OAP58301.1 - 0.015 15.0 0.1 0.89 9.3 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF4231 PF14015.1 OAP58301.1 - 0.14 12.1 0.1 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ank_2 PF12796.2 OAP58302.1 - 0.01 16.1 0.0 0.66 10.3 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP58302.1 - 0.047 13.9 0.8 51 4.3 0.0 4.9 4 2 2 6 6 6 0 Ankyrin repeats (many copies) UCH PF00443.24 OAP58303.1 - 1.8e-44 151.8 1.8 2.5e-44 151.4 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 OAP58303.1 - 1.4e-24 86.2 0.0 3.4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 OAP58303.1 - 4.5e-23 82.1 0.0 9.4e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2686 PF10887.3 OAP58303.1 - 0.28 9.8 0.0 0.52 9.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) RNase_P_pop3 PF08228.6 OAP58304.1 - 2.6e-09 37.0 0.0 9.9e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 RNase P subunit Pop3 ICMT PF04140.9 OAP58305.1 - 6.1e-28 96.8 1.2 1.1e-27 96.1 0.8 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAP58305.1 - 1.7e-15 57.0 0.9 1.7e-15 57.0 0.6 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 OAP58305.1 - 1.3e-05 24.6 0.9 1.6e-05 24.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 OAP58305.1 - 2.4e-05 23.0 1.0 3.3e-05 22.6 0.7 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Hexapep PF00132.19 OAP58306.1 - 2.3e-14 52.1 4.9 3.3e-11 42.1 2.6 2.9 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAP58306.1 - 2.9e-13 49.1 5.9 6.7e-10 38.3 2.6 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 OAP58306.1 - 1.3e-08 34.6 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase GST_C_3 PF14497.1 OAP58307.1 - 4.7e-10 39.8 0.0 6.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAP58307.1 - 5e-05 23.0 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP58307.1 - 0.0039 17.3 0.1 0.033 14.3 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Epimerase PF01370.16 OAP58308.1 - 1.1e-15 57.6 0.0 1.6e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP58308.1 - 3.4e-10 39.0 0.0 4.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP58308.1 - 3.1e-09 37.1 0.3 5.6e-09 36.2 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP58308.1 - 2.3e-08 33.3 0.0 2.9e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 OAP58308.1 - 2e-05 23.9 0.1 3.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 OAP58308.1 - 0.0018 18.1 0.8 0.0058 16.5 0.6 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP58308.1 - 0.021 14.5 2.2 4.4 6.9 0.0 2.3 2 1 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.10 OAP58308.1 - 0.078 11.8 0.1 1.1 8.0 0.1 2.2 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein DUF605 PF04652.11 OAP58309.1 - 10 5.4 10.2 13 5.0 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Methyltransf_2 PF00891.13 OAP58310.1 - 4.7e-29 101.2 0.0 7e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 OAP58310.1 - 3.2e-05 24.4 0.0 8.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP58310.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 OAP58310.1 - 0.024 13.8 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 OAP58310.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Sugar_tr PF00083.19 OAP58311.1 - 9.3e-123 410.1 29.4 1.1e-122 409.9 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58311.1 - 2.8e-24 85.5 40.3 3e-16 59.1 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP58311.1 - 1.1e-05 24.0 27.0 1.4e-05 23.7 6.6 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 OAP58311.1 - 0.0034 15.5 0.7 0.0034 15.5 0.5 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector Mitofilin PF09731.4 OAP58311.1 - 0.17 10.5 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MFS_1_like PF12832.2 OAP58311.1 - 6.2 6.6 13.2 3.4 7.5 1.2 3.6 3 1 0 3 3 3 0 MFS_1 like family HAD_2 PF13419.1 OAP58312.1 - 1e-15 58.4 0.0 2.6e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP58312.1 - 0.0012 18.4 0.0 0.0032 17.1 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.2 OAP58312.1 - 0.023 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase FTA4 PF13093.1 OAP58313.1 - 5.2e-58 195.9 8.1 6e-58 195.7 5.6 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_13 PF13166.1 OAP58313.1 - 0.025 13.0 1.3 0.2 10.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain P22_AR_C PF10548.4 OAP58313.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 P22AR C-terminal domain GAS PF13851.1 OAP58313.1 - 3 6.9 9.3 1.3 8.1 3.6 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sec62 PF03839.11 OAP58314.1 - 3.3e-56 190.2 3.4 3.3e-56 190.2 2.4 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 PAT1 PF09770.4 OAP58314.1 - 0.54 8.4 28.3 0.82 7.8 19.6 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_capsid PF06112.6 OAP58314.1 - 0.67 9.9 7.6 0.048 13.6 1.7 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein TMEM154 PF15102.1 OAP58315.1 - 0.066 12.9 0.0 0.066 12.9 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family Hamartin PF04388.7 OAP58315.1 - 4.4 5.8 7.5 6.7 5.2 5.2 1.1 1 0 0 1 1 1 0 Hamartin protein NmrA PF05368.8 OAP58316.1 - 6.7e-27 94.2 0.1 8.1e-27 93.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP58316.1 - 5.6e-13 49.3 0.0 9.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP58316.1 - 9.7e-06 24.4 0.0 1.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP58316.1 - 3.7e-05 23.2 0.1 9.5e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 OAP58316.1 - 0.0027 16.6 0.3 0.05 12.4 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain DapB_N PF01113.15 OAP58316.1 - 0.014 15.3 0.0 0.036 13.9 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 OAP58316.1 - 0.014 15.7 0.3 0.031 14.5 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 OAP58316.1 - 0.022 14.6 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 OAP58316.1 - 0.048 12.5 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Abhydrolase_3 PF07859.8 OAP58318.1 - 3.4e-23 82.3 0.0 5.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAP58318.1 - 9.3e-17 60.7 0.0 1.3e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAP58318.1 - 1.1e-05 25.1 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 OAP58318.1 - 0.073 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pkinase PF00069.20 OAP58320.1 - 4.7e-72 242.2 0.0 5.8e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58320.1 - 3.1e-31 108.3 0.0 3.9e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAP58320.1 - 2e-05 23.7 0.0 6.6e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAP58320.1 - 0.00018 20.6 0.0 0.026 13.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 OAP58320.1 - 0.00028 20.6 0.1 0.001 18.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 OAP58320.1 - 0.03 13.6 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.15 OAP58321.1 - 1.5e-127 425.5 0.3 1.8e-127 425.2 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAP58321.1 - 3.4e-15 55.7 1.2 1.9e-10 40.2 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAP58321.1 - 2.3e-05 23.6 0.1 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 OAP58321.1 - 0.0013 19.2 0.0 0.57 10.6 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 OAP58321.1 - 0.032 14.1 0.0 0.48 10.4 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAP58321.1 - 0.046 13.1 0.0 5.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 OAP58321.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.15 OAP58322.1 - 0 1085.1 0.3 0 1084.9 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Avl9 PF09794.4 OAP58323.1 - 6e-135 449.5 0.0 7.4e-135 449.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 OAP58323.1 - 1.4e-07 31.2 0.1 0.0015 18.2 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 OAP58323.1 - 0.00015 21.1 0.1 0.00015 21.1 0.1 3.1 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) DUF1205 PF06722.7 OAP58323.1 - 0.037 14.2 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) Cullin PF00888.17 OAP58324.1 - 7.3e-201 668.7 13.7 1e-200 668.2 9.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 OAP58324.1 - 8.2e-26 89.6 3.5 8.2e-26 89.6 2.4 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain HTH_34 PF13601.1 OAP58324.1 - 0.002 18.1 0.1 0.059 13.4 0.0 3.0 2 1 0 2 2 2 1 Winged helix DNA-binding domain WGG PF10273.4 OAP58324.1 - 0.12 12.4 3.0 19 5.4 0.0 3.9 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 Cupin_2 PF07883.6 OAP58325.1 - 4.6e-06 26.0 0.3 8.1e-06 25.2 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 OAP58325.1 - 2.6e-05 23.6 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 OAP58325.1 - 0.0095 15.5 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 OAP58325.1 - 0.022 14.6 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.14 OAP58325.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Mit_KHE1 PF10173.4 OAP58327.1 - 5.5e-59 199.1 0.0 8e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DSPc PF00782.15 OAP58328.1 - 3.8e-11 42.6 0.0 5.9e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain zf-UBR PF02207.15 OAP58330.1 - 1e-15 57.2 3.3 1e-15 57.2 2.3 3.5 4 0 0 4 4 4 2 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 OAP58331.1 - 9.1e-138 458.5 0.0 1.3e-137 458.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 OAP58331.1 - 7.6e-37 126.6 41.8 7.6e-37 126.6 28.9 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 OAP58331.1 - 1.7e-20 73.6 0.0 4e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAP58331.1 - 2.9e-08 33.1 0.1 2e-06 27.1 0.0 2.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAP58331.1 - 2.5e-06 27.2 0.0 6.5e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 OAP58331.1 - 0.0011 18.5 0.2 0.0075 15.7 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 OAP58331.1 - 0.0058 16.2 0.1 0.15 11.6 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF1272 PF06906.6 OAP58331.1 - 0.12 12.2 0.4 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_2 PF12674.2 OAP58331.1 - 0.18 12.1 0.5 0.67 10.3 0.4 2.0 1 0 0 1 1 1 0 Putative zinc ribbon domain SNF2_N PF00176.18 OAP58332.1 - 2.8e-69 233.2 0.1 5e-69 232.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP58332.1 - 6.3e-19 67.6 0.0 7.5e-18 64.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP58332.1 - 1.8e-05 24.6 1.9 4.7e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAP58332.1 - 0.00018 21.0 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Presenilin PF01080.12 OAP58332.1 - 5.6 5.6 5.6 11 4.7 3.9 1.4 1 0 0 1 1 1 0 Presenilin Glyco_hydro_31 PF01055.21 OAP58333.1 - 4.8e-25 88.2 0.2 6.8e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 OAP58333.1 - 1.1e-05 25.1 0.1 3e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Galactose mutarotase-like Transthyretin PF00576.16 OAP58333.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 HIUase/Transthyretin family Glyco_hydro_31 PF01055.21 OAP58334.1 - 7.1e-42 143.7 1.1 8.4e-42 143.5 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.21 OAP58335.1 - 2.4e-42 145.3 0.0 2.8e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Ank_2 PF12796.2 OAP58336.1 - 1.2e-38 131.2 11.7 1.8e-16 60.2 0.4 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 OAP58336.1 - 5.1e-32 108.0 18.8 1.8e-07 30.6 0.0 7.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 OAP58336.1 - 5.8e-30 103.1 15.4 6.2e-08 32.9 0.0 6.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP58336.1 - 1e-21 74.8 8.1 4.1e-05 23.4 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 OAP58336.1 - 1.2e-17 63.5 13.8 4.1e-07 30.0 0.1 6.3 3 2 4 7 7 6 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 OAP58336.1 - 1.8e-14 53.2 0.1 4.5e-14 51.9 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 OAP58336.1 - 1.9e-07 31.2 0.0 5.9e-05 23.1 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 OAP58336.1 - 5.9e-07 29.2 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 OAP58336.1 - 0.0011 19.0 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP58336.1 - 0.012 15.9 0.0 0.048 13.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 OAP58336.1 - 0.02 13.7 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DHHA1 PF02272.14 OAP58336.1 - 0.054 13.2 6.9 0.23 11.2 0.2 3.1 2 1 0 2 2 2 0 DHHA1 domain Viral_helicase1 PF01443.13 OAP58336.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 OAP58336.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 OAP58336.1 - 0.17 12.1 0.0 0.42 10.8 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 OAP58336.1 - 0.19 10.6 0.4 1 8.2 0.0 2.0 1 1 0 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.10 OAP58336.1 - 0.22 11.2 0.0 0.48 10.1 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 OAP58336.1 - 0.32 11.8 3.3 0.87 10.4 0.8 3.0 2 1 0 2 2 1 0 AAA domain Sulfate_transp PF00916.15 OAP58337.1 - 9.2e-54 182.3 7.4 2e-53 181.2 5.2 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 OAP58337.1 - 1.6e-29 101.3 3.7 1.6e-29 101.3 2.5 3.4 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 OAP58337.1 - 5.2e-14 51.6 0.0 1.3e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.1 OAP58337.1 - 0.0024 17.1 0.7 0.0056 15.9 0.5 1.5 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB STAS_2 PF13466.1 OAP58337.1 - 0.0057 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 STAS domain DUF1275 PF06912.6 OAP58338.1 - 1.1e-37 129.2 7.8 1.4e-37 128.9 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Adeno_GP19K PF04881.8 OAP58338.1 - 0.048 13.3 0.6 0.23 11.1 0.1 2.1 1 1 1 2 2 2 0 Adenovirus GP19K PAN_1 PF00024.21 OAP58340.1 - 0.0038 16.9 1.7 0.0049 16.5 0.0 2.0 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.1 OAP58340.1 - 0.083 12.6 0.1 0.083 12.6 0.1 1.9 2 0 0 2 2 2 0 PAN domain DUF3169 PF11368.3 OAP58340.1 - 0.14 11.3 0.1 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Macoilin PF09726.4 OAP58340.1 - 4.4 5.4 9.1 5.8 5.0 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Beta-lactamase PF00144.19 OAP58341.1 - 1.6e-20 73.3 2.0 2.7e-20 72.6 1.4 1.3 1 0 0 1 1 1 1 Beta-lactamase TatD_DNase PF01026.16 OAP58343.1 - 3.3e-35 121.5 0.0 6.7e-35 120.5 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase DUF2014 PF09427.5 OAP58344.1 - 8.4e-78 261.1 0.1 1.8e-77 259.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2014) HLH PF00010.21 OAP58344.1 - 3.7e-19 68.1 0.5 8.1e-19 67.0 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 OAP58344.1 - 0.00081 19.3 2.4 0.00092 19.1 0.2 2.0 2 0 0 2 2 2 1 bZIP transcription factor DUF904 PF06005.7 OAP58344.1 - 0.079 13.2 1.3 0.15 12.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Nnf1 PF03980.9 OAP58344.1 - 0.3 11.1 1.8 0.69 9.9 1.3 1.7 1 1 0 1 1 1 0 Nnf1 Anp1 PF03452.9 OAP58346.1 - 5.4e-104 347.1 0.0 6.9e-104 346.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 OAP58346.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_S10 PF00450.17 OAP58347.1 - 3.7e-87 293.1 6.7 1.2e-86 291.4 4.7 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase HhH-GPD PF00730.20 OAP58349.1 - 9.9e-06 25.7 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Adaptin_binding PF10199.4 OAP58349.1 - 0.0042 17.3 0.3 0.0071 16.6 0.2 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DSPc PF00782.15 OAP58350.1 - 2e-21 75.9 0.0 2.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 OAP58350.1 - 0.00022 20.2 0.0 0.00026 20.0 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 OAP58350.1 - 0.0024 17.2 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Nop16 PF09420.5 OAP58351.1 - 7.1e-56 188.8 11.0 8.3e-56 188.6 7.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.17 OAP58352.1 - 9.1e-61 205.5 11.0 3.4e-59 200.4 7.6 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3993 PF13158.1 OAP58352.1 - 0.094 12.5 0.2 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) SR-25 PF10500.4 OAP58352.1 - 0.79 9.1 11.7 1.3 8.3 8.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aldedh PF00171.17 OAP58353.1 - 4.5e-116 387.9 0.0 5.7e-116 387.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glycoprotein_B PF00606.13 OAP58354.1 - 0.42 8.5 2.0 0.46 8.4 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B NAD_binding_10 PF13460.1 OAP58355.1 - 5.9e-07 29.6 0.0 3.4e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP58355.1 - 0.0034 16.6 0.1 0.0056 15.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family RdRP PF05183.7 OAP58356.1 - 4.5e-127 425.1 0.0 7e-127 424.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.1 OAP58356.1 - 1.1e-46 158.8 0.0 2e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAP58356.1 - 1.3e-45 155.8 0.6 7.9e-44 149.9 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 OAP58356.1 - 3.6e-12 46.2 0.3 1.5e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAP58356.1 - 4.9e-12 45.4 0.0 4.2e-11 42.4 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 OAP58356.1 - 3.4e-06 26.7 0.0 0.057 12.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 OAP58356.1 - 7.6e-05 22.6 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 OAP58356.1 - 0.00023 20.8 0.0 0.00056 19.5 0.0 1.7 1 0 0 1 1 1 1 Helicase PhoH PF02562.11 OAP58356.1 - 0.00027 20.2 0.1 0.0011 18.3 0.0 2.1 2 1 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 OAP58356.1 - 0.0003 20.8 0.2 0.0027 17.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DEAD PF00270.24 OAP58356.1 - 0.001 18.5 0.1 0.0027 17.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAP58356.1 - 0.0016 18.5 0.0 0.012 15.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 OAP58356.1 - 0.0028 17.7 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain RNA_helicase PF00910.17 OAP58356.1 - 0.0061 16.7 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 OAP58356.1 - 0.0071 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 OAP58356.1 - 0.013 14.9 0.5 0.063 12.6 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 OAP58356.1 - 0.018 14.0 0.1 0.093 11.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 OAP58356.1 - 0.13 11.5 0.0 0.66 9.2 0.0 1.9 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 OAP58356.1 - 0.15 11.4 0.1 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 OAP58357.1 - 1.8e-28 99.5 0.0 2.2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAP58357.1 - 0.0011 19.0 0.1 0.0015 18.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 OAP58357.1 - 0.0032 18.2 0.0 0.0051 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP58357.1 - 0.0046 17.2 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAP58357.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 OAP58357.1 - 0.063 13.7 0.0 0.09 13.2 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 OAP58357.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Cu-oxidase_3 PF07732.10 OAP58359.1 - 5.5e-42 142.2 3.2 5.5e-42 142.2 2.2 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP58359.1 - 1.6e-41 141.0 10.5 6.8e-39 132.5 0.2 4.0 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 OAP58359.1 - 2.8e-35 121.5 0.2 8.6e-35 119.9 0.2 1.9 1 0 0 1 1 1 1 Multicopper oxidase Mt_ATP-synt_D PF05873.7 OAP58360.1 - 2.8e-13 49.7 0.3 3.3e-13 49.6 0.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Dor1 PF04124.7 OAP58360.1 - 0.019 13.4 0.4 0.024 13.1 0.3 1.1 1 0 0 1 1 1 0 Dor1-like family TPR_MLP1_2 PF07926.7 OAP58360.1 - 0.098 12.4 1.0 0.2 11.3 0.7 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein NEP PF10167.4 OAP58360.1 - 0.11 12.1 0.4 0.18 11.5 0.3 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein BLOC1_2 PF10046.4 OAP58360.1 - 0.12 12.5 1.8 3.9 7.6 0.5 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NAC PF01849.13 OAP58361.1 - 5.6e-23 80.2 0.0 3.1e-22 77.8 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 OAP58361.1 - 0.013 15.3 0.1 0.029 14.2 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Ribosomal_L14e PF01929.12 OAP58362.1 - 3.2e-27 94.6 1.0 4e-27 94.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 OAP58362.1 - 8.1e-05 22.1 0.2 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 KOW motif RGS PF00615.14 OAP58363.1 - 0.02 14.9 0.0 0.26 11.4 0.0 2.3 1 1 0 1 1 1 0 Regulator of G protein signaling domain 7tm_3 PF00003.17 OAP58363.1 - 0.56 9.5 11.3 1.1 8.4 7.8 1.6 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Methyltransf_23 PF13489.1 OAP58364.1 - 3.3e-16 59.4 0.0 5.9e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP58364.1 - 3.2e-13 49.9 0.0 1.5e-12 47.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP58364.1 - 2.2e-11 43.5 0.0 3.8e-09 36.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP58364.1 - 5.6e-08 33.3 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAP58364.1 - 8.4e-08 31.6 0.0 2.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 OAP58364.1 - 1e-06 29.1 0.0 2.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP58364.1 - 1.3e-06 28.6 0.1 1.6e-05 25.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Sterol_MT_C PF08498.5 OAP58364.1 - 3.7e-06 26.7 0.0 7.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_26 PF13659.1 OAP58364.1 - 5.7e-05 23.1 0.0 0.00024 21.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAP58364.1 - 0.00018 21.0 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 OAP58364.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 OAP58364.1 - 0.028 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 OAP58364.1 - 0.074 12.7 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain GTP_EFTU PF00009.22 OAP58365.1 - 2.7e-62 209.5 0.1 3.9e-62 209.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAP58365.1 - 9.8e-37 125.1 0.0 2.9e-36 123.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 OAP58365.1 - 1.5e-21 76.0 0.0 1.1e-20 73.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAP58365.1 - 4.6e-13 49.0 2.1 1.4e-12 47.5 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 OAP58365.1 - 4.9e-12 45.5 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 OAP58365.1 - 7.2e-06 25.9 0.2 2.3e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF1490 PF07371.7 OAP58365.1 - 0.087 12.7 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) Solute_trans_a PF03619.11 OAP58366.1 - 7.6e-104 346.8 8.9 9.1e-104 346.5 6.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MFS_1 PF07690.11 OAP58368.1 - 1.7e-44 151.9 23.8 1.7e-44 151.9 16.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP58368.1 - 1.1e-12 47.3 10.0 1.1e-12 47.3 6.9 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAP58368.1 - 3.9e-09 35.2 2.0 5.9e-09 34.6 1.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 OAP58368.1 - 0.00056 19.6 0.1 0.0026 17.4 0.1 2.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) DUF4234 PF14018.1 OAP58368.1 - 0.048 13.4 1.3 5 6.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) Rick_17kDa_Anti PF05433.10 OAP58369.1 - 2.8e-07 30.0 10.1 4.9e-07 29.3 7.0 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 OAP58369.1 - 0.0015 18.1 0.2 0.0033 17.0 0.1 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain ATPase_gene1 PF09527.5 OAP58369.1 - 0.0071 16.1 1.0 0.011 15.5 0.7 1.1 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit (ATPase_gene1) Gly-zipper_Omp PF13488.1 OAP58369.1 - 2.9 7.5 13.0 5.2 6.7 2.7 2.4 1 1 1 2 2 2 0 Glycine zipper ABC_tran PF00005.22 OAP58370.1 - 1.4e-47 161.4 0.3 1.1e-23 84.0 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAP58370.1 - 2.4e-16 60.5 0.5 0.0018 18.2 0.1 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 OAP58370.1 - 9.7e-16 57.6 0.1 1.2e-06 27.8 0.0 3.5 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAP58370.1 - 3.2e-11 43.9 2.5 4e-05 24.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 OAP58370.1 - 1.8e-10 40.1 0.1 0.00058 19.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAP58370.1 - 2.2e-07 30.2 0.0 0.00087 18.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAP58370.1 - 2.2e-07 31.7 0.0 0.0032 18.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 OAP58370.1 - 2.2e-06 27.6 0.0 0.024 14.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 OAP58370.1 - 3.3e-06 27.1 0.0 0.032 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain HEAT_2 PF13646.1 OAP58370.1 - 5.6e-06 26.5 0.1 0.21 11.8 0.1 3.7 2 1 1 3 3 3 1 HEAT repeats AAA_22 PF13401.1 OAP58370.1 - 7e-06 26.2 0.0 0.068 13.3 0.0 3.4 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 OAP58370.1 - 1.2e-05 25.1 0.0 0.031 14.2 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 OAP58370.1 - 1.2e-05 24.8 0.1 0.21 11.0 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 OAP58370.1 - 1.9e-05 24.7 0.0 0.35 10.8 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.24 OAP58370.1 - 2.3e-05 24.5 0.2 0.62 10.2 0.0 4.5 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 OAP58370.1 - 2.7e-05 24.0 0.0 0.16 11.7 0.0 3.6 2 1 1 3 3 3 2 Domain of unknown function DUF87 Miro PF08477.8 OAP58370.1 - 4e-05 24.0 0.0 0.05 14.1 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 OAP58370.1 - 4.2e-05 23.0 0.0 0.13 11.7 0.0 3.0 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 OAP58370.1 - 4.3e-05 23.8 0.4 0.19 12.0 0.0 3.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 OAP58370.1 - 6e-05 22.7 0.0 0.065 12.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.18 OAP58370.1 - 6e-05 22.9 0.0 0.0058 16.4 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.1 OAP58370.1 - 6.7e-05 22.7 0.0 0.29 10.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 OAP58370.1 - 0.00011 21.0 0.2 0.32 9.7 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_15 PF13175.1 OAP58370.1 - 0.00021 20.4 5.7 0.71 8.8 0.0 4.3 2 2 1 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.17 OAP58370.1 - 0.00025 21.1 0.0 0.67 10.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 OAP58370.1 - 0.00027 20.6 0.0 1 9.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 OAP58370.1 - 0.0012 18.7 0.0 3.3 7.6 0.0 3.3 4 0 0 4 4 2 0 AAA domain Arch_ATPase PF01637.13 OAP58370.1 - 0.0013 18.4 0.1 0.68 9.5 0.0 2.9 3 0 0 3 3 2 1 Archaeal ATPase AAA_13 PF13166.1 OAP58370.1 - 0.0021 16.6 2.8 1.1 7.6 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 OAP58370.1 - 0.0022 17.5 0.1 3.9 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 OAP58370.1 - 0.0037 16.7 0.0 3.3 7.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 OAP58370.1 - 0.0061 16.0 0.0 4.6 6.6 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 OAP58370.1 - 0.011 14.5 0.2 1.4 7.7 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 OAP58370.1 - 0.012 15.1 0.0 4.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 OAP58370.1 - 0.017 14.1 0.7 1.8 7.4 0.0 2.8 3 0 0 3 3 2 0 Septin ATP-synt_ab PF00006.20 OAP58370.1 - 0.018 14.5 0.0 5.5 6.4 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MutS_V PF00488.16 OAP58370.1 - 0.022 14.1 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 MutS domain V FtsK_SpoIIIE PF01580.13 OAP58370.1 - 0.023 14.1 0.2 1.9 7.9 0.0 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family G-alpha PF00503.15 OAP58370.1 - 0.026 13.2 0.1 0.84 8.2 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.9 OAP58370.1 - 0.029 14.0 0.1 16 5.1 0.0 3.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAP58370.1 - 0.034 13.9 0.1 4.8 6.9 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 OAP58370.1 - 0.058 12.5 0.0 2.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 OAP58370.1 - 0.062 12.2 0.0 9.5 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 OAP58370.1 - 0.064 12.1 0.4 0.61 8.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.12 OAP58370.1 - 0.094 12.1 0.0 15 4.9 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein HEAT PF02985.17 OAP58370.1 - 0.14 12.2 0.2 54 4.2 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat Pyr_redox_3 PF13738.1 OAP58371.1 - 6.1e-17 62.3 0.0 1.5e-16 61.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP58371.1 - 5e-14 51.3 0.7 7.5e-12 44.2 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP58371.1 - 1.3e-09 37.8 0.0 2.1e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP58371.1 - 1.5e-06 27.4 0.1 9.5e-06 24.7 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP58371.1 - 2.9e-06 27.1 0.4 0.0042 16.8 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 OAP58371.1 - 5.8e-05 22.1 0.2 0.039 12.8 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 OAP58371.1 - 0.021 13.8 0.1 0.82 8.7 0.0 2.6 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.9 OAP58371.1 - 0.038 12.4 0.4 0.56 8.6 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 OAP58371.1 - 0.058 12.2 1.5 6.9 5.4 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 OAP58371.1 - 0.11 11.9 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Cu_amine_oxid PF01179.15 OAP58372.1 - 3.6e-90 302.6 0.0 3.6e-77 259.8 0.0 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 OAP58372.1 - 4e-15 55.4 0.0 1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 OAP58372.1 - 0.00066 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Clr5 PF14420.1 OAP58374.1 - 7.8e-17 60.9 3.3 1e-16 60.5 1.3 2.0 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.1 OAP58374.1 - 3.9e-05 23.5 2.2 0.004 17.0 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP58374.1 - 0.048 14.3 1.2 0.68 10.7 0.4 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP58374.1 - 0.19 11.6 2.7 2.6 8.0 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAP58374.1 - 0.43 10.5 4.5 5 7.1 0.8 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP58374.1 - 0.59 10.1 3.3 2 8.4 0.9 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CDC37_N PF03234.9 OAP58375.1 - 1.6e-58 197.9 8.4 1.6e-58 197.9 5.8 3.1 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 OAP58375.1 - 1.6e-45 154.6 4.6 1.6e-45 154.6 3.2 2.5 2 1 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 OAP58375.1 - 8.2e-29 99.3 1.0 8.2e-29 99.3 0.7 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain ABC_membrane PF00664.18 OAP58376.1 - 2.7e-43 148.3 12.4 3.5e-43 147.9 8.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 OAP58376.1 - 1.9e-36 125.3 0.0 4.6e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 OAP58376.1 - 2.4e-07 30.2 0.0 0.00014 21.1 0.0 3.1 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP58376.1 - 0.0014 18.6 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP58376.1 - 0.0019 17.6 0.0 0.0049 16.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 OAP58376.1 - 0.0043 16.5 0.1 0.028 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 OAP58376.1 - 0.0051 16.9 0.1 0.04 14.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAP58376.1 - 0.0059 16.0 0.0 0.045 13.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_ATPase PF09818.4 OAP58376.1 - 0.0069 15.0 0.1 0.026 13.1 0.1 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_17 PF13207.1 OAP58376.1 - 0.012 16.3 0.0 0.03 15.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAP58376.1 - 0.019 14.4 0.1 0.074 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 OAP58376.1 - 0.027 14.6 0.0 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 OAP58376.1 - 0.029 14.6 0.6 0.089 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 OAP58376.1 - 0.046 13.2 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 OAP58376.1 - 0.089 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 OAP58376.1 - 0.098 12.6 2.4 0.33 10.9 0.4 2.6 2 1 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 OAP58376.1 - 0.18 11.7 4.3 0.23 11.3 0.4 3.1 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit MBOAT PF03062.14 OAP58377.1 - 7.4e-17 61.4 20.9 1.3e-16 60.6 14.6 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 OAP58377.1 - 0.0017 18.3 4.6 0.0059 16.6 3.2 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2515 PF10720.4 OAP58377.1 - 0.011 14.6 0.6 0.15 10.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2515) WD40 PF00400.27 OAP58378.1 - 2.8e-44 147.4 23.0 5.3e-10 38.7 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 OAP58378.1 - 0.02 13.2 0.1 0.039 12.2 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain PAT1 PF09770.4 OAP58378.1 - 9.6 4.3 10.8 14 3.7 7.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 OAP58379.1 - 2.4e-47 157.1 12.5 3.7e-08 32.9 0.2 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 OAP58379.1 - 1.3e-05 25.0 0.0 0.0024 17.6 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 OAP58379.1 - 5.4e-05 21.5 0.5 0.03 12.4 0.1 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 OAP58379.1 - 0.088 11.0 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Orbi_VP6 PF01516.11 OAP58379.1 - 9.8 5.1 13.6 16 4.4 9.4 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF1774 PF08611.5 OAP58381.1 - 7.9 6.7 8.5 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) DUF4188 PF13826.1 OAP58382.1 - 6.9e-31 106.7 0.3 1.2e-30 106.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 OAP58382.1 - 0.00035 19.7 0.7 0.00045 19.3 0.5 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase ABM PF03992.11 OAP58382.1 - 0.073 13.1 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Dabb PF07876.7 OAP58382.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain MSC PF09402.5 OAP58383.1 - 4.4e-93 311.6 0.0 6.2e-93 311.1 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 OAP58383.1 - 1.2e-14 53.5 0.2 1.2e-14 53.5 0.1 1.8 2 0 0 2 2 2 1 HeH/LEM domain DUF3637 PF12337.3 OAP58383.1 - 0.062 13.2 0.1 0.24 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) TFIIA PF03153.8 OAP58383.1 - 0.18 11.6 7.7 0.27 11.0 5.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM171 PF15471.1 OAP58383.1 - 4.2 6.0 7.8 7.6 5.2 5.4 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Ribosomal_L16 PF00252.13 OAP58385.1 - 6.7e-31 106.7 0.1 9e-31 106.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.21 OAP58386.1 - 9.1e-25 86.0 0.0 1e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TSC22 PF01166.13 OAP58387.1 - 1.2 9.1 26.2 0.18 11.7 0.3 4.2 4 0 0 4 4 4 0 TSC-22/dip/bun family His_Phos_1 PF00300.17 OAP58388.1 - 2.8e-11 43.7 1.5 1.2e-10 41.6 0.1 2.4 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) HECT PF00632.20 OAP58389.1 - 2.3e-73 247.1 0.0 3.6e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Tim17 PF02466.14 OAP58390.1 - 6.9e-34 116.6 6.2 8.6e-34 116.3 4.3 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UPF0126 PF03458.8 OAP58390.1 - 5.1 6.7 8.0 9.1 5.9 1.4 2.9 2 2 1 3 3 3 0 UPF0126 domain TraQ PF09679.5 OAP58391.1 - 0.023 14.6 2.6 0.028 14.3 0.0 2.3 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF77 PF01910.12 OAP58392.1 - 1.2e-32 111.4 0.1 1.4e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 OAP58392.1 - 0.053 13.6 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family DUF1335 PF07056.6 OAP58392.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) DUF3425 PF11905.3 OAP58393.1 - 1.7e-13 50.6 0.1 6.3e-13 48.7 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.13 OAP58394.1 - 1.6e-06 27.1 0.4 5.4e-06 25.4 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58394.1 - 2.9e-05 23.8 7.0 2.9e-05 23.8 4.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 OAP58394.1 - 0.0056 16.9 4.1 0.0056 16.9 2.9 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP58394.1 - 0.63 10.5 11.8 0.051 13.9 2.9 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2039 PF10217.4 OAP58394.1 - 3.5 7.7 10.5 10 6.1 7.3 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) adh_short PF00106.20 OAP58395.1 - 2.1e-18 66.7 0.2 3.5e-17 62.8 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 OAP58395.1 - 0.012 15.5 0.2 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 OAP58395.1 - 0.031 13.9 0.1 0.33 10.5 0.1 2.3 2 0 0 2 2 2 0 KR domain Abhydrolase_5 PF12695.2 OAP58395.1 - 0.086 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PRP4 PF08799.6 OAP58395.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like TrkA_N PF02254.13 OAP58395.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 OAP58396.1 - 1.4e-11 44.2 0.3 3.2e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP58396.1 - 5.5e-06 26.5 0.0 2.2e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP58396.1 - 0.073 11.9 0.4 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 OAP58396.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 OAP58396.1 - 0.11 11.3 0.1 0.41 9.4 0.1 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP58396.1 - 0.13 10.6 0.1 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 OAP58396.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain p450 PF00067.17 OAP58397.1 - 1.5e-43 149.0 0.0 1.9e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 OAP58398.1 - 3.8e-07 29.2 1.5 6.4e-06 25.2 1.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3425 PF11905.3 OAP58399.1 - 3.8e-17 62.4 0.4 1.4e-16 60.6 0.0 2.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) Pyr_redox_3 PF13738.1 OAP58400.1 - 1.6e-20 74.0 0.0 1.2e-18 67.9 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP58400.1 - 3.5e-13 48.6 0.3 4e-12 45.1 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP58400.1 - 4.5e-09 35.6 0.2 1.2e-05 24.4 0.0 3.5 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP58400.1 - 3.2e-07 30.2 0.0 9.8e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP58400.1 - 4.3e-06 26.7 0.0 0.0011 18.8 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP58400.1 - 0.0093 15.7 1.0 0.042 13.6 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 OAP58400.1 - 0.094 12.2 0.2 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.13 OAP58401.1 - 2.5e-20 72.4 0.7 5.1e-20 71.4 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 OAP58402.1 - 3e-19 69.5 5.0 1.3e-18 67.4 3.5 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58402.1 - 4.3e-12 46.3 0.3 3.1e-11 43.5 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58402.1 - 2.4e-10 40.3 0.7 3.4e-10 39.8 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP58402.1 - 1.4e-06 27.9 0.2 2.1e-06 27.3 0.0 1.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAP58402.1 - 7.3e-06 25.7 0.2 1e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAP58402.1 - 2.3e-05 24.4 0.8 0.0015 18.5 0.5 2.2 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 OAP58402.1 - 0.00021 20.4 0.4 0.00028 20.0 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Adenylsucc_synt PF00709.16 OAP58402.1 - 0.052 12.2 0.1 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Sugar_tr PF00083.19 OAP58403.1 - 4.6e-75 252.9 30.5 5.4e-75 252.6 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58403.1 - 1.1e-29 103.2 28.6 1.1e-29 103.2 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 OAP58404.1 - 5.2e-17 62.5 0.0 1.7e-15 57.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP58404.1 - 2.6e-15 55.6 0.1 1.4e-13 49.8 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP58404.1 - 3e-08 33.5 0.0 9.2e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP58404.1 - 1.2e-07 30.9 0.1 0.0008 18.4 0.0 3.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Malic_M PF03949.10 OAP58404.1 - 0.00076 19.1 0.3 0.066 12.7 0.0 2.2 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain NAD_binding_9 PF13454.1 OAP58404.1 - 0.0041 16.9 0.2 0.35 10.6 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding CoA_binding PF02629.14 OAP58404.1 - 0.2 12.1 0.8 24 5.5 0.0 2.3 2 0 0 2 2 2 0 CoA binding domain p450 PF00067.17 OAP58405.1 - 1.8e-62 211.3 0.0 2.3e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF749 PF05370.6 OAP58405.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF749) Cyclase PF04199.8 OAP58406.1 - 4.8e-17 62.1 0.0 6.8e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short PF00106.20 OAP58407.1 - 1.4e-25 90.1 0.2 2.3e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58407.1 - 1.2e-23 84.1 0.0 1.4e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58407.1 - 1.6e-07 31.1 0.2 4.2e-07 29.8 0.1 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 OAP58407.1 - 0.056 12.1 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAP58409.1 - 5.1e-35 120.8 0.8 6.9e-35 120.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58409.1 - 1.6e-28 100.0 0.0 2.1e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58409.1 - 3.1e-16 59.5 0.1 5e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP58409.1 - 0.00067 19.1 0.1 0.0014 18.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CABS1 PF15367.1 OAP58409.1 - 0.0051 15.7 0.0 0.0067 15.3 0.0 1.1 1 0 0 1 1 1 1 Calcium-binding and spermatid-specific protein 1 THF_DHG_CYH_C PF02882.14 OAP58409.1 - 0.059 12.4 0.1 0.69 8.9 0.0 2.6 3 1 1 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GST_N PF02798.15 OAP58410.1 - 1.7e-09 37.6 0.0 5.4e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP58410.1 - 8.7e-08 32.0 0.0 2.1e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP58410.1 - 2e-07 31.3 0.1 2.9e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP58410.1 - 2.4e-07 30.8 0.0 4.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP58410.1 - 1.2e-06 28.3 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP58410.1 - 2.2e-06 27.5 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CM_2 PF01817.16 OAP58412.1 - 0.32 11.1 3.3 0.72 9.9 0.4 2.4 2 0 0 2 2 2 0 Chorismate mutase type II Big_3_4 PF13754.1 OAP58413.1 - 0.011 16.0 0.2 0.011 16.0 0.1 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Metallophos PF00149.23 OAP58414.1 - 1.4e-07 31.0 3.5 2.5e-06 27.0 2.4 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP58414.1 - 6.5e-05 22.8 0.0 0.00016 21.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Zeta_toxin PF06414.7 OAP58416.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TPR_10 PF13374.1 OAP58416.1 - 0.17 11.8 4.5 4.9 7.2 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP58416.1 - 0.19 11.7 2.0 43 4.3 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_pol_lambd_f PF10391.4 OAP58417.1 - 3.9e-20 71.1 0.3 8.2e-20 70.0 0.2 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 OAP58417.1 - 1.1e-16 60.9 0.0 2.1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 OAP58417.1 - 4.3e-14 51.9 0.0 2.2e-13 49.6 0.0 2.2 2 1 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 OAP58417.1 - 7.5e-09 35.6 0.1 1.7e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 OAP58417.1 - 0.017 15.2 0.0 0.72 10.0 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 OAP58417.1 - 0.03 14.6 0.1 0.072 13.4 0.1 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Ribophorin_I PF04597.9 OAP58418.1 - 5.9e-142 473.1 0.0 6.7e-142 473.0 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Xan_ur_permease PF00860.15 OAP58418.1 - 0.14 10.6 0.1 0.34 9.3 0.0 1.5 2 0 0 2 2 2 0 Permease family 2Fe-2S_thioredx PF01257.14 OAP58419.1 - 2.6e-60 202.2 0.2 3.5e-60 201.7 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin F-box-like PF12937.2 OAP58420.1 - 4.4e-07 29.5 0.4 8.5e-07 28.6 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP58420.1 - 3.5e-05 23.3 0.0 9.5e-05 21.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 OAP58420.1 - 0.013 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain Mannitol_dh_C PF08125.8 OAP58420.1 - 0.067 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain VTC PF09359.5 OAP58421.1 - 3.8e-103 344.3 1.4 3.9e-103 344.3 0.0 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 OAP58421.1 - 3.5e-22 79.4 24.7 3.6e-21 76.1 11.5 3.9 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 OAP58421.1 - 1.9e-10 40.7 3.7 4.2e-10 39.6 2.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Rad17 PF03215.10 OAP58422.1 - 1.3e-54 185.8 0.0 2.3e-54 184.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Peptidase_M16 PF00675.15 OAP58422.1 - 5.7e-05 22.9 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) AAA_19 PF13245.1 OAP58422.1 - 0.00015 21.4 0.0 0.00047 19.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 OAP58422.1 - 0.001 19.2 0.0 0.0028 17.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 OAP58422.1 - 0.0057 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP58422.1 - 0.0059 17.4 0.0 0.016 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAP58422.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 OAP58422.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 OAP58422.1 - 0.051 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 OAP58422.1 - 0.063 13.2 0.1 0.17 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 OAP58422.1 - 0.063 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 OAP58422.1 - 0.088 11.6 0.3 0.16 10.8 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 OAP58422.1 - 0.092 12.4 0.3 0.32 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Nbs1_C PF08599.5 OAP58422.1 - 1.6 8.7 4.2 23 5.0 0.3 2.7 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 zf-DHHC PF01529.15 OAP58423.1 - 3.7e-32 111.1 4.4 5.3e-32 110.6 2.6 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase PSI PF01437.20 OAP58423.1 - 0.028 14.5 2.7 0.061 13.4 1.8 1.5 1 0 0 1 1 1 0 Plexin repeat zf-UBR PF02207.15 OAP58423.1 - 0.09 12.5 6.4 0.15 11.8 4.5 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) MARVEL PF01284.18 OAP58424.1 - 9e-10 38.5 19.5 2.7e-08 33.7 12.7 2.1 1 1 1 2 2 2 2 Membrane-associating domain Claudin_3 PF06653.6 OAP58424.1 - 0.029 14.1 13.1 0.035 13.8 3.1 2.2 1 1 1 2 2 2 0 Tight junction protein, Claudin-like VWA_2 PF13519.1 OAP58425.1 - 8.8e-13 48.7 2.1 1.7e-12 47.8 1.5 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 OAP58425.1 - 8.4e-09 35.3 1.9 9.4e-09 35.2 0.3 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF605 PF04652.11 OAP58425.1 - 0.027 13.8 33.5 0.046 13.1 23.2 1.3 1 0 0 1 1 1 0 Vta1 like DUF1034 PF06280.7 OAP58425.1 - 0.083 13.3 0.8 0.2 12.0 0.5 1.6 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) Mito_carr PF00153.22 OAP58426.1 - 5.2e-62 205.5 0.4 1.5e-20 72.6 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 OAP58427.1 - 9.1e-07 28.5 0.2 1.8e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP58427.1 - 0.00072 19.1 0.2 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 OAP58427.1 - 0.036 13.7 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 OAP58427.1 - 0.039 13.8 0.2 0.42 10.6 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 OAP58427.1 - 0.071 12.9 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain KAR9 PF08580.5 OAP58428.1 - 1e-98 331.4 4.6 1.6e-98 330.7 3.2 1.2 1 0 0 1 1 1 1 Yeast cortical protein KAR9 FemAB PF02388.11 OAP58428.1 - 0.036 12.7 0.4 0.16 10.6 0.0 2.1 2 0 0 2 2 2 0 FemAB family DNA_repr_REX1B PF14966.1 OAP58428.1 - 0.059 13.7 1.6 16 5.9 0.1 3.1 2 0 0 2 2 2 0 DNA repair REX1-B Prominin PF05478.6 OAP58428.1 - 0.089 10.3 3.1 0.51 7.8 0.2 2.3 2 1 0 2 2 2 0 Prominin RuvA_C PF07499.8 OAP58428.1 - 0.13 12.4 0.8 0.35 11.0 0.6 1.8 1 0 0 1 1 1 0 RuvA, C-terminal domain DUF4332 PF14229.1 OAP58428.1 - 0.13 12.1 3.1 0.37 10.7 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4332) Val_tRNA-synt_C PF10458.4 OAP58428.1 - 0.6 10.2 3.1 0.73 9.9 0.2 2.7 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Cast PF10174.4 OAP58428.1 - 0.65 7.9 9.0 0.12 10.3 1.4 2.3 2 1 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone AOX PF01786.12 OAP58429.1 - 9.7e-88 292.9 0.1 1.2e-87 292.6 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase Acylphosphatase PF00708.13 OAP58430.1 - 1.2e-26 92.5 0.2 1.3e-26 92.4 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase GFA PF04828.9 OAP58432.1 - 1.6e-21 76.0 0.0 2.1e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 OAP58432.1 - 0.051 13.3 0.0 0.051 13.3 0.0 2.2 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Aldolase_II PF00596.16 OAP58433.1 - 2.4e-45 154.3 0.2 3.1e-45 154.0 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Anillin PF08174.6 OAP58434.1 - 1.1e-27 96.8 0.0 2.8e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 OAP58434.1 - 1.5e-10 41.1 0.0 3.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAP58434.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain DEAD PF00270.24 OAP58435.1 - 4e-31 107.7 0.0 8.7e-31 106.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP58435.1 - 3.7e-14 52.3 0.0 8.5e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP58435.1 - 0.0035 17.1 0.0 0.018 14.9 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAP58435.1 - 0.0057 15.4 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 OAP58435.1 - 0.11 10.9 0.8 0.29 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) HA2 PF04408.18 OAP58436.1 - 2.1e-18 66.2 0.0 4.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAP58436.1 - 9.1e-16 57.7 0.0 2.1e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAP58436.1 - 5.1e-14 51.8 0.0 1.8e-13 50.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP58436.1 - 1.6e-05 24.4 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 OAP58436.1 - 0.0057 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 OAP58436.1 - 0.013 15.6 0.0 0.043 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 OAP58436.1 - 0.02 13.8 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 OAP58436.1 - 0.059 13.6 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 OAP58436.1 - 0.087 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PIR PF00399.14 OAP58437.1 - 9.5e-76 246.8 154.1 1.2e-06 27.6 1.5 16.3 2 1 14 16 16 16 16 Yeast PIR protein repeat Methyltransf_26 PF13659.1 OAP58438.1 - 8.8e-18 64.4 0.2 1.6e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP58438.1 - 0.079 12.3 2.8 2.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase small domain Cullin PF00888.17 OAP58439.1 - 1.2e-43 149.5 0.0 2.2e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 OAP58439.1 - 6.9e-18 64.6 0.0 1.4e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Fungal_trans_2 PF11951.3 OAP58440.1 - 7.7e-07 28.0 0.0 1.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.11 OAP58441.1 - 1.3e-19 70.9 0.0 1.6e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UDP-g_GGTase PF06427.6 OAP58443.1 - 1.5e-66 223.7 0.0 2.9e-66 222.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 OAP58443.1 - 0.00023 20.5 0.1 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 TRI12 PF06609.8 OAP58444.1 - 2.4e-28 98.6 24.1 2.9e-28 98.4 16.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP58444.1 - 3.2e-16 58.9 56.0 3.2e-16 58.9 38.8 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Podoplanin PF05808.6 OAP58444.1 - 0.18 11.3 0.0 0.18 11.3 0.0 2.4 3 0 0 3 3 3 0 Podoplanin DUF4066 PF13278.1 OAP58445.1 - 7.3e-11 41.6 0.0 8.9e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 OAP58445.1 - 0.00034 20.0 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family FAD_binding_4 PF01565.18 OAP58446.1 - 3.6e-18 65.3 0.0 5.9e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Glycophorin_A PF01102.13 OAP58447.1 - 0.0098 15.6 3.5 0.014 15.1 0.2 2.5 2 0 0 2 2 2 1 Glycophorin A VSP PF03302.8 OAP58447.1 - 0.025 13.1 0.8 0.041 12.5 0.5 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.5 OAP58447.1 - 0.24 10.7 3.0 0.79 9.0 0.1 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Trp_oprn_chp PF09534.5 OAP58447.1 - 8.6 5.9 8.8 0.66 9.5 0.6 2.5 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) adh_short PF00106.20 OAP58448.1 - 5.7e-20 71.8 1.0 7.8e-20 71.4 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58448.1 - 1.1e-13 51.5 0.0 1.4e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58448.1 - 5.2e-09 36.0 0.2 7e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP58448.1 - 3.8e-05 22.7 0.0 4.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 OAP58448.1 - 0.00047 20.2 0.1 0.00076 19.5 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.8 OAP58448.1 - 0.0023 17.3 0.1 0.24 10.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family F420_oxidored PF03807.12 OAP58448.1 - 0.0043 17.4 0.4 0.01 16.2 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAP58448.1 - 0.007 16.0 0.7 0.011 15.3 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAP58448.1 - 0.013 14.7 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 OAP58448.1 - 0.03 13.7 0.5 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ApbA PF02558.11 OAP58448.1 - 0.1 12.0 0.1 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 OAP58448.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 OAP58448.1 - 0.14 11.9 0.1 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 ThiF family Fusion_gly PF00523.13 OAP58448.1 - 0.25 9.3 0.7 0.37 8.8 0.5 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 PALP PF00291.20 OAP58449.1 - 3.7e-58 197.1 0.1 5.8e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 OAP58449.1 - 1.8e-07 30.8 0.1 2.4e-06 27.2 0.0 2.6 3 0 0 3 3 3 1 CBS domain RRM_1 PF00076.17 OAP58450.1 - 1.7e-12 46.7 0.0 2.5e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP58450.1 - 6e-07 29.3 0.0 9.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP58450.1 - 1.5e-06 27.9 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAP58450.1 - 0.00048 19.8 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 OAP58450.1 - 8.6 4.6 15.4 11 4.3 10.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mito_carr PF00153.22 OAP58451.1 - 1.1e-75 249.4 2.7 6.4e-25 86.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 OAP58452.1 - 1.7e-26 93.0 0.1 1.7e-26 93.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 tRNA_anti-like PF12869.2 OAP58452.1 - 0.034 13.6 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like Aldedh PF00171.17 OAP58453.1 - 1.1e-11 43.7 8.4 2.2e-09 36.1 3.4 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family CDC45 PF02724.9 OAP58454.1 - 4.4 5.2 14.6 4.4 5.2 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Metalloenzyme PF01676.13 OAP58455.1 - 9.2e-74 247.9 0.0 1.1e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 OAP58455.1 - 1.5e-70 237.0 0.0 2e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 OAP58455.1 - 1.2e-07 31.4 0.0 2.5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 OAP58455.1 - 2.3e-06 27.0 0.0 7.3e-05 22.0 0.0 2.6 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.15 OAP58455.1 - 0.0062 15.2 0.1 0.031 12.9 0.0 1.9 2 0 0 2 2 2 1 Alkaline phosphatase Fungal_trans PF04082.13 OAP58456.1 - 4.4e-15 55.2 3.2 4.8e-15 55.1 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58456.1 - 3e-06 27.0 10.7 4.8e-06 26.3 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1219 PF06755.7 OAP58456.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1219) bZIP_2 PF07716.10 OAP58456.1 - 0.11 12.2 1.5 0.26 11.1 1.0 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Amidase PF01425.16 OAP58457.1 - 4.8e-62 210.2 0.3 9.9e-60 202.6 0.1 2.1 2 0 0 2 2 2 2 Amidase PPO1_DWL PF12142.3 OAP58459.1 - 0.0027 17.1 0.3 0.023 14.1 0.0 2.3 2 0 0 2 2 2 1 Polyphenol oxidase middle domain Abhydrolase_6 PF12697.2 OAP58460.1 - 2.3e-34 119.2 4.3 2.7e-34 119.0 3.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP58460.1 - 5e-20 72.0 0.1 5.8e-12 45.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP58460.1 - 7e-15 55.0 2.3 3.4e-14 52.8 1.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 OAP58460.1 - 0.011 14.2 0.0 0.041 12.3 0.0 1.8 2 0 0 2 2 2 0 Ndr family Hydrolase_4 PF12146.3 OAP58460.1 - 0.033 14.0 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase FSH1 PF03959.8 OAP58460.1 - 0.083 12.3 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 OAP58460.1 - 0.091 12.6 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein DUF2410 PF10307.4 OAP58461.1 - 3.2e-72 242.0 0.0 5e-72 241.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DUF3431 PF11913.3 OAP58462.1 - 1.6e-60 204.3 0.0 2e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Evr1_Alr PF04777.8 OAP58463.1 - 7.9e-28 96.2 1.9 2.5e-27 94.5 0.6 1.9 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.1 OAP58463.1 - 0.098 12.5 0.1 9.9 6.0 0.1 2.1 2 0 0 2 2 2 0 Bd3614-like deaminase DUF3593 PF12159.3 OAP58465.1 - 0.027 14.2 0.0 0.03 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) EntA_Immun PF08951.5 OAP58465.1 - 0.037 14.1 0.1 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 Enterocin A Immunity Potassium_chann PF11404.3 OAP58465.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Potassium voltage-gated channel Pyr_redox_3 PF13738.1 OAP58466.1 - 3.5e-23 82.7 0.0 8.5e-22 78.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP58466.1 - 2.8e-16 59.9 0.0 4e-13 49.6 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP58466.1 - 9e-15 54.4 0.0 8.6e-10 38.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 OAP58466.1 - 6.2e-14 51.0 0.0 1.4e-12 46.5 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 OAP58466.1 - 5.2e-11 42.7 0.1 0.0038 17.5 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP58466.1 - 1.3e-10 41.4 0.7 2.3e-05 24.5 0.0 3.2 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 OAP58466.1 - 2.3e-08 33.5 0.2 7.8e-08 31.7 0.1 1.9 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 OAP58466.1 - 8.2e-08 31.5 0.2 0.0037 16.2 0.1 4.4 2 1 1 5 5 5 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP58466.1 - 2.4e-06 27.3 2.0 0.12 12.1 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAP58466.1 - 1.5e-05 24.8 0.0 0.00012 22.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP58466.1 - 3.6e-05 22.4 0.2 0.00022 19.8 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein ThiF PF00899.16 OAP58466.1 - 4.9e-05 23.1 0.1 0.14 11.9 0.1 2.6 2 0 0 2 2 2 2 ThiF family 2-Hacid_dh_C PF02826.14 OAP58466.1 - 4.9e-05 22.5 0.0 0.035 13.2 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAP58466.1 - 6.4e-05 22.6 0.2 0.069 12.7 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 OAP58466.1 - 8.5e-05 21.5 0.1 0.015 14.1 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 OAP58466.1 - 0.00012 21.0 0.6 0.1 11.4 0.0 2.8 3 1 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 OAP58466.1 - 0.00018 21.7 0.0 0.55 10.5 0.0 2.6 3 0 0 3 3 2 2 Putative NAD(P)-binding IlvN PF07991.7 OAP58466.1 - 0.0013 18.1 0.1 0.29 10.4 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 OAP58466.1 - 0.0015 17.5 0.1 0.079 11.8 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 OAP58466.1 - 0.0074 15.4 0.2 0.12 11.4 0.0 2.5 3 0 0 3 3 3 1 Thi4 family F420_oxidored PF03807.12 OAP58466.1 - 0.01 16.2 1.1 0.12 12.8 0.0 2.7 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 OAP58466.1 - 0.032 14.2 0.2 7.2 6.6 0.0 3.1 3 0 0 3 3 3 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 OAP58466.1 - 0.033 13.9 0.3 10 5.7 0.0 2.6 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 OAP58466.1 - 0.046 12.3 3.4 1.4 7.4 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase FAD_oxidored PF12831.2 OAP58466.1 - 0.071 12.1 0.2 0.12 11.4 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 OAP58466.1 - 0.071 12.6 0.0 9 5.8 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 OAP58466.1 - 0.096 12.1 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 OAP58467.1 - 2e-68 231.0 0.0 2.6e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 OAP58467.1 - 1e-06 27.8 0.1 6.3e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 OAP58467.1 - 1.1e-06 27.8 0.0 6.1e-05 22.0 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 OAP58467.1 - 2.9e-06 26.6 0.2 6.6e-05 22.1 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 OAP58467.1 - 3.9e-05 22.6 0.0 6.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAP58467.1 - 4.4e-05 23.6 0.1 0.00048 20.2 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP58467.1 - 5.6e-05 21.7 0.0 9.7e-05 21.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAP58467.1 - 6.7e-05 22.8 0.0 0.00024 21.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP58467.1 - 0.00014 21.0 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 OAP58467.1 - 0.0002 21.3 0.0 0.00087 19.2 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP58467.1 - 0.0015 17.5 0.1 0.085 11.7 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAP58467.1 - 0.051 13.3 0.1 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyoxalase PF00903.20 OAP58468.1 - 1.5e-12 47.5 1.1 9.7e-08 32.0 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP58468.1 - 6.8e-12 45.9 0.6 4.2e-07 30.5 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 OAP58468.1 - 0.00036 20.4 0.0 1.1 9.2 0.0 3.4 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.13 OAP58469.1 - 2.9e-25 88.6 0.4 6e-25 87.5 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58469.1 - 1.5e-08 34.4 11.9 2.7e-08 33.5 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOA36 PF06524.7 OAP58469.1 - 0.066 12.4 2.7 0.099 11.8 1.9 1.2 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.1 OAP58469.1 - 0.39 9.8 1.9 0.62 9.2 1.3 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Phage_base_V PF04717.7 OAP58470.1 - 0.049 13.5 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Phage-related baseplate assembly protein ABC_membrane PF00664.18 OAP58471.1 - 9.2e-72 241.7 43.4 1.5e-38 132.7 12.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAP58471.1 - 1.2e-64 216.7 0.0 5.8e-33 114.0 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAP58471.1 - 1.3e-15 57.2 1.3 0.00019 20.7 0.0 4.7 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP58471.1 - 3.7e-14 53.3 0.1 0.00091 19.2 0.0 4.4 3 2 0 4 4 3 3 AAA domain AAA_16 PF13191.1 OAP58471.1 - 2.1e-10 40.9 4.1 4.1e-06 26.9 0.3 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 OAP58471.1 - 9.2e-10 38.7 0.1 0.0022 18.1 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAP58471.1 - 1.1e-08 34.4 0.4 9.7e-05 21.8 0.2 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAP58471.1 - 2e-08 33.6 0.0 0.0057 15.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAP58471.1 - 2.4e-08 34.8 0.0 0.0099 16.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 OAP58471.1 - 2.9e-06 27.5 1.2 1.2 9.2 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 OAP58471.1 - 7.5e-06 25.6 0.1 0.46 10.1 0.0 3.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 OAP58471.1 - 9.1e-06 25.5 0.0 0.25 11.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAP58471.1 - 1.2e-05 24.8 0.0 0.13 11.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 OAP58471.1 - 1.2e-05 25.7 0.5 0.29 11.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 OAP58471.1 - 3.9e-05 23.9 0.0 0.51 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 OAP58471.1 - 6.5e-05 22.5 0.1 0.24 10.9 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 OAP58471.1 - 9.9e-05 22.0 0.0 1.2 8.8 0.0 3.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAP58471.1 - 0.00022 20.9 0.0 0.56 10.0 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 OAP58471.1 - 0.00024 20.9 1.6 0.56 10.1 0.1 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 OAP58471.1 - 0.0013 18.6 3.8 0.29 11.0 0.1 3.4 4 1 0 4 4 3 1 AAA domain AAA_14 PF13173.1 OAP58471.1 - 0.0021 17.9 0.0 3.4 7.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.10 OAP58471.1 - 0.0066 15.1 0.0 0.28 9.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 OAP58471.1 - 0.007 15.4 0.1 1.4 7.9 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin SRP54 PF00448.17 OAP58471.1 - 0.0077 15.6 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 OAP58471.1 - 0.0094 15.4 0.1 0.89 8.9 0.0 2.9 3 0 0 3 3 2 1 AAA-like domain RNA_helicase PF00910.17 OAP58471.1 - 0.011 15.9 0.0 5.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 OAP58471.1 - 0.014 14.7 0.6 6.7 6.0 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_24 PF13479.1 OAP58471.1 - 0.015 14.8 2.2 2.3 7.7 0.0 3.1 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.17 OAP58471.1 - 0.025 13.4 0.0 0.96 8.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.18 OAP58471.1 - 0.03 14.2 0.0 9.6 6.2 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase PRK PF00485.13 OAP58471.1 - 0.043 13.3 0.0 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 OAP58471.1 - 0.083 12.5 0.0 13 5.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 OAP58471.1 - 0.098 12.1 0.0 5.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Secretin PF00263.16 OAP58471.1 - 0.4 10.0 3.4 6 6.2 0.0 3.2 4 0 0 4 4 3 0 Bacterial type II and III secretion system protein PAN_3 PF08277.7 OAP58472.1 - 2e-06 27.3 3.4 0.00047 19.7 0.1 2.8 2 1 0 2 2 2 2 PAN-like domain PAN_1 PF00024.21 OAP58472.1 - 2.1e-05 24.1 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.1 OAP58472.1 - 0.93 9.2 9.4 6.6 6.5 0.5 3.5 3 0 0 3 3 3 0 PAN domain DUF2183 PF09949.4 OAP58475.1 - 2.9e-19 68.8 0.1 6.3e-19 67.7 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) adh_short PF00106.20 OAP58476.1 - 2.7e-22 79.4 2.3 3.9e-14 52.9 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58476.1 - 2.8e-17 63.2 0.3 5.4e-16 59.1 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58476.1 - 4.8e-08 32.8 1.3 8.5e-08 32.0 0.1 1.9 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 OAP58476.1 - 0.003 17.6 0.1 0.0054 16.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 OAP58476.1 - 0.0081 15.6 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 OAP58476.1 - 0.027 14.8 0.4 0.092 13.1 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 OAP58476.1 - 0.03 14.3 0.2 0.1 12.5 0.1 1.8 1 1 1 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 OAP58476.1 - 0.079 12.6 0.2 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 OAP58476.1 - 0.091 12.2 0.1 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1767 PF08585.7 OAP58477.1 - 3.7e-15 55.9 0.0 8.9e-15 54.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 OAP58478.1 - 2.2e-39 132.9 36.9 1.2e-07 31.2 0.0 13.1 13 1 1 14 14 14 11 TPR repeat TPR_1 PF00515.23 OAP58478.1 - 3e-31 105.7 18.0 0.0002 20.7 0.0 13.1 16 0 0 16 16 14 6 Tetratricopeptide repeat TPR_16 PF13432.1 OAP58478.1 - 1.2e-30 105.5 51.3 1.6e-07 31.8 0.4 14.4 10 4 4 15 15 14 8 Tetratricopeptide repeat TPR_2 PF07719.12 OAP58478.1 - 4.6e-30 101.0 40.7 0.00052 19.7 0.1 17.3 19 0 0 19 19 18 7 Tetratricopeptide repeat TPR_14 PF13428.1 OAP58478.1 - 1.3e-28 96.8 55.4 6.4e-05 23.2 0.2 18.8 15 4 6 21 21 18 7 Tetratricopeptide repeat TPR_17 PF13431.1 OAP58478.1 - 1.8e-28 96.3 17.2 0.0015 18.5 0.1 16.4 18 1 1 19 19 19 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAP58478.1 - 3.8e-24 84.8 39.3 8.2e-08 32.4 0.2 12.0 9 4 5 14 14 14 8 Tetratricopeptide repeat TPR_12 PF13424.1 OAP58478.1 - 2.8e-20 72.0 39.3 0.00016 21.5 0.1 13.1 8 4 4 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 OAP58478.1 - 1.8e-19 67.9 7.9 0.082 12.7 0.0 12.8 14 1 1 15 15 14 4 Tetratricopeptide repeat TPR_7 PF13176.1 OAP58478.1 - 1.1e-18 65.5 12.1 0.014 15.1 0.1 11.5 9 2 2 11 11 11 4 Tetratricopeptide repeat Apc3 PF12895.2 OAP58478.1 - 8.5e-10 38.6 24.9 0.00035 20.6 0.0 8.4 8 1 1 9 9 9 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 OAP58478.1 - 1.5e-06 28.2 34.7 0.23 12.0 0.1 14.2 19 0 0 19 19 15 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAP58478.1 - 2.2e-05 24.2 14.1 0.038 13.8 0.4 7.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 OAP58478.1 - 0.0011 19.0 28.4 0.081 13.0 0.1 8.6 7 2 2 9 9 9 3 Tetratricopeptide repeat Apc5 PF12862.2 OAP58478.1 - 0.0042 16.8 4.7 0.034 13.9 0.1 4.3 4 0 0 4 4 3 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 OAP58478.1 - 0.21 11.5 16.8 11 6.0 0.1 7.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Methyltransf_11 PF08241.7 OAP58479.1 - 8.2e-13 48.6 0.0 2.5e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP58479.1 - 8.5e-11 41.4 0.0 2.5e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 OAP58479.1 - 1.4e-10 40.9 0.0 1.3e-09 37.8 0.0 1.9 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP58479.1 - 2.3e-10 40.7 0.0 2.6e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP58479.1 - 2.1e-08 34.0 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP58479.1 - 1.4e-07 31.8 0.0 2.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP58479.1 - 2.2e-07 30.8 0.0 5.5e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP58479.1 - 0.00018 20.8 0.0 0.00052 19.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 OAP58479.1 - 0.0011 19.4 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PepSY_2 PF13670.1 OAP58479.1 - 0.042 13.7 0.1 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain NAD_binding_10 PF13460.1 OAP58480.1 - 2e-19 70.3 0.0 2.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP58480.1 - 1.9e-16 60.2 0.0 4e-16 59.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP58480.1 - 6.9e-14 51.2 0.0 2.2e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 OAP58480.1 - 1.8e-13 50.2 0.0 2.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 OAP58480.1 - 3.2e-10 39.3 0.0 6.8e-09 35.0 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 OAP58480.1 - 8e-09 34.7 0.0 6.3e-05 22.0 0.0 3.2 1 1 1 2 2 2 2 Male sterility protein Saccharop_dh PF03435.13 OAP58480.1 - 5.6e-05 22.2 0.0 9.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 OAP58480.1 - 0.00056 19.8 0.0 0.0071 16.2 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAP58480.1 - 0.0075 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 OAP58480.1 - 0.029 14.0 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 KR domain DDE_Tnp_1_3 PF13612.1 OAP58480.1 - 0.063 13.0 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain DapB_N PF01113.15 OAP58480.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.11 OAP58480.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 OAP58480.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 OAP58481.1 - 0.00017 21.3 4.0 0.00017 21.3 2.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP58482.1 - 7.2e-25 87.4 36.4 7.2e-25 87.4 25.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2306 PF10067.4 OAP58483.1 - 3.6e-13 49.4 6.5 3.6e-13 49.4 4.5 2.4 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) Zn_clus PF00172.13 OAP58484.1 - 1e-08 34.8 8.5 1.8e-08 34.1 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sporozoite_P67 PF05642.6 OAP58485.1 - 1.3 6.7 4.8 1.3 6.7 3.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2163 PF09931.4 OAP58486.1 - 0.055 13.2 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) zf-C3Hc3H PF13891.1 OAP58486.1 - 0.1 12.6 1.4 0.49 10.4 0.0 2.5 3 0 0 3 3 3 0 Potential DNA-binding domain p450 PF00067.17 OAP58487.1 - 7e-63 212.7 0.0 9e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_2 PF12681.2 OAP58488.1 - 1.5e-06 28.8 0.0 3.1e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Adaptin_N PF01602.15 OAP58489.1 - 7.7e-149 496.3 2.9 1e-148 495.9 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAP58489.1 - 1.3e-26 93.5 0.2 1.8e-25 89.8 0.1 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 OAP58489.1 - 1.8e-18 66.5 1.5 4.5e-07 30.0 0.0 5.8 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.17 OAP58489.1 - 6e-10 38.3 7.6 0.016 15.2 0.0 6.4 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 OAP58489.1 - 0.00065 20.1 4.9 4.5 7.8 0.0 6.5 7 1 1 8 8 8 1 HEAT-like repeat Cohesin_HEAT PF12765.2 OAP58489.1 - 0.0087 16.0 0.1 3.3 7.7 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.3 OAP58489.1 - 0.036 13.4 0.1 3.1 7.0 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.4 OAP58489.1 - 0.067 12.9 0.0 1.2 8.9 0.0 2.7 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain AF0941-like PF14591.1 OAP58489.1 - 0.25 11.4 1.7 1.1 9.3 1.2 2.1 1 0 0 1 1 1 0 AF0941-like zf-CCCH PF00642.19 OAP58490.1 - 0.0004 20.0 1.0 0.0007 19.2 0.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 OAP58490.1 - 0.63 10.1 4.4 1.7 8.7 3.1 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_S10 PF00338.17 OAP58491.1 - 2.1e-29 101.2 0.5 2.5e-29 100.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 OAP58492.1 - 3.2e-06 26.5 0.0 6.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain Xpo1 PF08389.7 OAP58493.1 - 4.1e-07 30.0 4.7 3.9e-06 26.8 0.4 4.2 3 1 0 3 3 3 1 Exportin 1-like protein E2F_TDP PF02319.15 OAP58493.1 - 0.026 14.0 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain GRIM-19 PF06212.7 OAP58494.1 - 5.1e-20 71.4 0.1 7.8e-20 70.9 0.0 1.3 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 OAP58495.1 - 1.7e-30 106.0 0.0 4.5e-24 85.0 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase IncFII_repA PF02387.10 OAP58495.1 - 2.7 7.0 10.6 4.5 6.3 7.3 1.2 1 0 0 1 1 1 0 IncFII RepA protein family APG6 PF04111.7 OAP58495.1 - 8.7 5.2 10.0 14 4.6 6.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cellulase PF00150.13 OAP58496.1 - 7.3e-16 58.1 0.7 4.1e-11 42.6 0.1 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 OAP58496.1 - 0.0007 18.8 0.3 0.12 11.4 0.1 2.2 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.14 OAP58496.1 - 0.0087 15.4 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Pkinase PF00069.20 OAP58497.1 - 4e-74 249.0 0.0 5e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58497.1 - 5e-32 111.0 0.0 6.5e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP58497.1 - 0.00061 18.8 0.0 0.0016 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 OAP58497.1 - 0.0024 16.9 0.1 0.0041 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP58497.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAP58497.1 - 0.051 12.4 0.1 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.14 OAP58497.1 - 0.056 12.7 0.1 0.19 11.0 0.1 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.10 OAP58498.1 - 9.4e-73 244.5 0.0 1.8e-72 243.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAP58498.1 - 5.5e-24 83.5 0.1 5.5e-23 80.3 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAP58498.1 - 5e-18 65.4 0.1 1.1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 OAP58498.1 - 7.4e-18 63.8 5.3 1.3e-17 63.1 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 OAP58498.1 - 6.6e-09 35.3 0.0 1.7e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat HET PF06985.6 OAP58500.1 - 2e-05 24.7 0.0 4.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1772 PF08592.6 OAP58501.1 - 1.4e-18 66.9 0.9 3.7e-18 65.5 0.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Ctr PF04145.10 OAP58501.1 - 0.02 14.9 0.8 6 6.9 0.0 2.5 1 1 0 2 2 2 0 Ctr copper transporter family Ribosomal_S19e PF01090.14 OAP58502.1 - 4e-54 181.8 0.2 4.7e-54 181.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ring_hydroxyl_A PF00848.14 OAP58504.1 - 1.3e-19 70.6 0.4 7e-19 68.3 0.4 2.1 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 OAP58504.1 - 7.2e-14 51.1 0.0 1.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF3405 PF11885.3 OAP58505.1 - 5e-158 526.4 6.2 6.5e-158 526.0 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) eIF2A PF08662.6 OAP58508.1 - 1.3e-82 276.1 0.0 1.5e-80 269.4 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 OAP58508.1 - 9.8e-05 22.0 2.0 12 5.9 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF605 PF04652.11 OAP58508.1 - 1.9 7.8 17.7 2.9 7.1 12.3 1.2 1 0 0 1 1 1 0 Vta1 like Apc1 PF12859.2 OAP58510.1 - 1e-18 67.4 0.1 2.7e-18 66.1 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 OAP58510.1 - 2.6e-07 30.4 0.1 0.0011 19.1 0.0 4.0 3 0 0 3 3 3 2 Proteasome/cyclosome repeat Aldose_epim PF01263.15 OAP58511.1 - 1.2e-67 228.1 0.1 1.5e-67 227.8 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.13 OAP58512.1 - 7.4e-09 35.3 13.4 1.2e-08 34.6 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TLD PF07534.11 OAP58513.1 - 1.1e-25 90.2 0.0 8.6e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 TLD VID27 PF08553.5 OAP58514.1 - 0 1099.0 1.3 0 1098.9 0.9 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Vps51 PF08700.6 OAP58515.1 - 1.8e-24 85.3 1.4 3e-24 84.6 0.3 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 OAP58515.1 - 3.4e-06 26.8 0.1 7.1e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG5 PF10392.4 OAP58515.1 - 0.0019 18.1 0.2 0.0044 16.9 0.1 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 OAP58515.1 - 0.099 11.5 0.3 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Fungal_trans_2 PF11951.3 OAP58516.1 - 1.5e-09 36.9 0.2 2.2e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PCI PF01399.22 OAP58517.1 - 1.7e-09 37.9 0.0 6.6e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 OAP58517.1 - 0.011 16.0 0.1 0.035 14.4 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP58517.1 - 0.025 14.4 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP58517.1 - 0.035 14.7 0.0 0.19 12.4 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAP58517.1 - 0.035 13.8 0.1 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP58517.1 - 0.076 12.9 0.1 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Imm42 PF15601.1 OAP58517.1 - 0.08 12.3 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 42 DnaB_bind PF10410.4 OAP58517.1 - 0.095 12.7 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Ribosomal_S17 PF00366.15 OAP58518.1 - 3.9e-06 26.8 0.1 7.9e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Glyco_transf_20 PF00982.16 OAP58519.1 - 1.7e-200 666.4 0.0 2e-200 666.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 OAP58519.1 - 0.056 12.9 0.7 0.14 11.6 0.0 2.0 3 0 0 3 3 3 0 Starch synthase catalytic domain Zn_clus PF00172.13 OAP58520.1 - 0.0027 17.5 7.7 0.006 16.4 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 OAP58520.1 - 0.32 9.1 14.4 0.39 8.8 9.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Prenyltrans PF00432.16 OAP58521.1 - 8.8e-39 130.7 35.8 1.9e-10 40.1 2.2 6.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAP58521.1 - 5.5e-26 91.2 0.2 9.9e-17 61.3 0.1 4.3 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAP58521.1 - 0.00029 20.8 0.1 0.005 16.8 0.0 2.8 2 1 1 3 3 3 1 Prenyltransferase-like dsrm PF00035.20 OAP58521.1 - 0.0064 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 OAP58521.1 - 0.031 14.5 0.1 0.066 13.5 0.1 1.5 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 HTH_33 PF13592.1 OAP58521.1 - 0.093 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DUF607 PF04678.8 OAP58522.1 - 2.1e-42 145.0 0.0 6e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF607 HEM4 PF02602.10 OAP58524.1 - 3.7e-26 91.7 0.0 1.8e-13 50.3 0.0 4.1 3 1 0 3 3 3 3 Uroporphyrinogen-III synthase HemD Lactamase_B PF00753.22 OAP58525.1 - 1.8e-14 53.8 2.6 3.4e-14 52.9 1.5 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP58525.1 - 0.00026 20.6 0.1 0.00035 20.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP58525.1 - 0.028 14.1 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Aconitase PF00330.15 OAP58526.1 - 3.4e-175 582.9 0.0 8.3e-175 581.7 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAP58526.1 - 3.8e-47 159.6 0.0 6.1e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 OAP58527.1 - 3.2e-08 33.4 3.3 6.7e-08 32.4 2.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 OAP58527.1 - 0.0028 17.8 1.6 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 OAP58527.1 - 0.0039 17.4 2.0 0.0039 17.4 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.2 OAP58527.1 - 0.0094 16.1 3.7 0.021 15.0 1.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type HAUS2 PF15003.1 OAP58527.1 - 0.038 13.0 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 zf-C2H2_2 PF12756.2 OAP58527.1 - 0.063 13.3 2.0 0.12 12.5 1.3 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.3 OAP58527.1 - 0.11 12.6 0.2 0.15 12.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3268) zf-U1 PF06220.7 OAP58527.1 - 0.14 11.6 0.9 0.3 10.6 0.6 1.5 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.1 OAP58527.1 - 0.79 10.1 5.0 0.62 10.5 0.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Mito_carr PF00153.22 OAP58528.1 - 3.6e-42 141.9 7.2 3.5e-20 71.5 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.18 OAP58529.1 - 2.4e-66 223.5 0.0 3.2e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 OAP58529.1 - 6.3e-53 179.4 0.8 2.3e-52 177.6 0.8 1.8 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 OAP58529.1 - 2.2e-13 49.8 0.0 6.9e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 OAP58529.1 - 1.2e-05 24.2 0.0 5.3e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 OAP58529.1 - 0.0028 17.5 0.0 0.013 15.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Vac14_Fig4_bd PF11916.3 OAP58530.1 - 1.1e-82 275.6 4.4 1.1e-82 275.6 3.0 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 OAP58530.1 - 3.5e-34 117.0 0.2 5.9e-30 103.5 0.2 4.9 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 OAP58530.1 - 2e-08 33.6 1.3 0.00015 21.5 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 OAP58530.1 - 4.6e-06 26.9 3.0 0.00062 20.1 0.1 4.3 3 1 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.1 OAP58530.1 - 0.00013 22.2 5.1 0.08 13.2 0.1 5.0 6 1 1 7 7 7 2 HEAT repeats Arm PF00514.18 OAP58530.1 - 0.0041 16.8 0.0 0.51 10.2 0.0 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat ABC_tran PF00005.22 OAP58532.1 - 2.7e-34 118.3 0.0 6.2e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 OAP58532.1 - 4.3e-33 114.9 14.5 5.9e-33 114.4 10.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 OAP58532.1 - 5.6e-08 33.0 0.2 0.0015 18.5 0.1 2.6 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 OAP58532.1 - 2.6e-06 26.8 0.1 0.0027 16.9 0.0 2.6 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 OAP58532.1 - 1.4e-05 25.9 0.0 3.6e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAP58532.1 - 3.3e-05 23.9 0.0 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 OAP58532.1 - 0.00013 21.9 0.0 0.0023 17.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAP58532.1 - 0.00057 20.0 0.0 0.0067 16.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAP58532.1 - 0.002 17.3 0.0 0.0041 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 OAP58532.1 - 0.0024 18.1 0.0 0.01 16.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 OAP58532.1 - 0.0027 17.1 0.0 0.0081 15.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 OAP58532.1 - 0.017 15.0 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 OAP58532.1 - 0.023 14.8 0.0 0.12 12.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 OAP58532.1 - 0.028 14.3 0.7 0.65 9.9 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 OAP58532.1 - 0.038 13.5 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 OAP58532.1 - 0.055 13.7 0.2 0.19 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 OAP58532.1 - 0.061 13.1 0.3 0.43 10.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 OAP58532.1 - 0.073 13.0 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.10 OAP58532.1 - 0.083 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 OAP58532.1 - 0.09 12.4 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DAO PF01266.19 OAP58533.1 - 1.1e-30 106.7 0.4 1.3e-30 106.5 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP58533.1 - 7.6e-06 25.9 0.1 0.00056 19.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP58533.1 - 4.5e-05 23.2 0.2 0.12 12.1 0.0 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 OAP58533.1 - 9.7e-05 21.3 0.0 0.00047 19.1 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.13 OAP58533.1 - 0.0017 18.3 0.0 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 OAP58533.1 - 0.0026 16.7 0.2 0.062 12.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP58533.1 - 0.0045 17.0 0.1 0.24 11.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP58533.1 - 0.025 14.5 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GDI PF00996.13 OAP58533.1 - 0.058 11.7 0.0 0.29 9.4 0.0 1.9 2 0 0 2 2 2 0 GDP dissociation inhibitor MFS_1 PF07690.11 OAP58534.1 - 4.6e-32 111.1 34.5 1.4e-24 86.4 17.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP58534.1 - 2.9e-12 45.9 2.7 2.9e-12 45.9 1.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 OAP58534.1 - 6.1e-06 24.8 4.7 6.1e-06 24.8 3.3 3.3 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.8 OAP58534.1 - 0.0027 15.9 6.6 0.032 12.3 1.5 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Ferritin_2 PF13668.1 OAP58535.1 - 0.027 14.4 0.1 0.055 13.4 0.0 1.5 2 0 0 2 2 2 0 Ferritin-like domain AIM24 PF01987.12 OAP58536.1 - 1.6e-40 138.8 0.0 2.2e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 OAP58536.1 - 0.0062 17.0 0.2 0.046 14.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4402) BTB PF00651.26 OAP58537.1 - 5e-12 45.7 0.0 8.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MIF4G_like_2 PF09090.6 OAP58538.1 - 0.052 12.7 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 MIF4G like DUF3425 PF11905.3 OAP58539.1 - 1e-16 61.0 0.3 1e-16 61.0 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) MT PF12777.2 OAP58539.1 - 0.35 9.5 1.6 0.5 9.0 1.1 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor bZIP_1 PF00170.16 OAP58539.1 - 2.2 8.3 10.8 5.3 7.0 7.5 1.6 1 1 0 1 1 1 0 bZIP transcription factor Pox_A_type_inc PF04508.7 OAP58539.1 - 2.3 8.2 9.6 0.16 11.8 0.3 3.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Acyl-CoA_dh_1 PF00441.19 OAP58540.1 - 1.3e-22 80.5 1.7 1.9e-22 79.9 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAP58540.1 - 1.3e-12 48.2 0.0 2.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAP58540.1 - 3.6e-10 39.1 0.0 7.4e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAP58540.1 - 4.7e-06 26.8 0.2 7.8e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.23 OAP58541.1 - 5e-86 288.7 0.0 6.1e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP58541.1 - 3.8e-12 46.9 0.1 9.3e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.1 OAP58542.1 - 3.3e-27 95.8 0.0 4.1e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP58542.1 - 3e-23 82.5 0.4 3.9e-23 82.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP58542.1 - 1.1e-06 28.4 0.8 3.9e-06 26.6 0.5 1.7 1 1 0 1 1 1 1 KR domain CLU PF13236.1 OAP58542.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Clustered mitochondria Cyclase PF04199.8 OAP58543.1 - 3.3e-18 65.9 0.5 4.3e-18 65.5 0.3 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 OAP58544.1 - 1e-73 248.5 23.6 1.2e-73 248.3 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58544.1 - 1.2e-19 70.2 26.8 1.2e-19 70.2 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.18 OAP58545.1 - 3.2e-39 135.0 0.1 5.8e-39 134.2 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 OAP58545.1 - 0.00013 21.0 0.0 0.0024 16.8 0.0 2.3 1 1 0 1 1 1 1 Fructosamine kinase EcKinase PF02958.15 OAP58545.1 - 0.00065 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 OAP58545.1 - 0.013 14.8 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Glyoxalase_2 PF12681.2 OAP58545.1 - 0.022 15.3 0.1 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase-like domain DUF1679 PF07914.6 OAP58545.1 - 0.17 10.4 0.0 3.3 6.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) BTB PF00651.26 OAP58546.1 - 3.7e-09 36.5 0.0 5.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain EMP24_GP25L PF01105.19 OAP58547.1 - 3.3e-44 150.7 0.0 4.2e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 OAP58547.1 - 0.011 13.9 0.5 0.015 13.5 0.3 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DASH_Spc34 PF08657.5 OAP58549.1 - 2e-47 162.0 11.8 1.5e-25 90.3 1.2 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 SlyX PF04102.7 OAP58549.1 - 0.17 12.3 5.5 4 7.8 0.4 3.8 3 1 1 4 4 4 0 SlyX zf-C4H2 PF10146.4 OAP58549.1 - 0.2 11.6 6.2 0.13 12.2 2.8 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein XhlA PF10779.4 OAP58549.1 - 5.1 7.0 7.0 3.3 7.6 0.3 2.5 1 1 1 2 2 2 0 Haemolysin XhlA IncA PF04156.9 OAP58549.1 - 7.8 6.0 10.4 24 4.4 7.1 1.8 1 1 0 1 1 1 0 IncA protein Rpn3_C PF08375.6 OAP58550.1 - 3.1e-24 85.1 0.7 3.1e-24 85.1 0.5 2.4 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 OAP58550.1 - 2.5e-20 72.7 0.2 9.1e-20 70.9 0.0 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 OAP58550.1 - 0.00019 21.1 0.2 0.00071 19.3 0.1 1.9 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 DAP PF15228.1 OAP58550.1 - 0.42 11.3 0.1 0.42 11.3 0.1 3.0 3 0 0 3 3 3 0 Death-associated protein DASH_Dam1 PF08653.5 OAP58551.1 - 8.4e-21 73.4 0.4 1.4e-20 72.7 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.24 OAP58553.1 - 1.3e-51 175.2 0.2 1.8e-51 174.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAP58553.1 - 2.5e-21 76.4 5.3 3.2e-20 72.7 3.7 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAP58553.1 - 5.3e-05 23.2 1.7 0.0092 16.0 0.5 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein Macoilin PF09726.4 OAP58553.1 - 1.1 7.4 9.1 0.25 9.5 0.8 2.2 2 0 0 2 2 2 0 Transmembrane protein Ytp1 PF10355.4 OAP58554.1 - 1e-112 375.8 11.6 1e-112 375.8 8.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 OAP58554.1 - 2.9e-28 97.5 9.3 2.9e-28 97.5 6.5 3.4 5 0 0 5 5 5 2 Domain of unknown function (DUF2427) Clr5 PF14420.1 OAP58555.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Clr5 domain RNA_pol_Rpb5_N PF03871.9 OAP58555.1 - 0.12 12.8 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Rhomboid PF01694.17 OAP58556.1 - 2.8e-17 63.1 8.0 2.8e-17 63.1 5.5 1.5 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.9 OAP58557.1 - 1.9e-104 350.2 8.6 2.5e-104 349.7 5.9 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component GFA PF04828.9 OAP58558.1 - 2.1e-16 59.6 3.5 2.9e-10 39.9 0.0 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme ApbA PF02558.11 OAP58559.1 - 1.3e-28 99.3 0.0 2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 OAP58559.1 - 2.8e-25 88.7 0.0 6.8e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Saccharop_dh PF03435.13 OAP58559.1 - 0.0083 15.1 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase Glyco_hydro_18 PF00704.23 OAP58560.1 - 7e-94 315.0 1.6 8.7e-94 314.7 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RasGAP PF00616.14 OAP58561.1 - 1.1e-51 175.3 1.3 1.4e-51 174.9 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 OAP58561.1 - 2.8e-30 104.8 0.3 2.8e-30 104.8 0.2 2.9 3 0 0 3 3 3 1 RasGAP C-terminus MitMem_reg PF13012.1 OAP58561.1 - 0.021 14.9 0.2 0.021 14.9 0.1 3.2 4 0 0 4 4 4 0 Maintenance of mitochondrial structure and function CD36 PF01130.16 OAP58561.1 - 0.083 11.1 0.0 0.15 10.3 0.0 1.3 1 0 0 1 1 1 0 CD36 family DUF972 PF06156.8 OAP58561.1 - 4.3 7.7 8.1 13 6.2 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Beta-lactamase PF00144.19 OAP58562.1 - 2.1e-44 151.9 0.9 3e-44 151.4 0.7 1.2 1 0 0 1 1 1 1 Beta-lactamase Coatomer_WDAD PF04053.9 OAP58563.1 - 1.3e-148 495.4 0.0 2.4e-148 494.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 OAP58563.1 - 5.1e-91 305.3 0.0 7.4e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 OAP58563.1 - 9.4e-48 158.4 9.7 1.3e-08 34.3 0.1 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat SET PF00856.23 OAP58563.1 - 3.9e-13 50.0 0.0 1.2e-12 48.4 0.0 1.9 1 0 0 1 1 1 1 SET domain Nup160 PF11715.3 OAP58563.1 - 0.013 13.6 6.7 0.69 7.9 0.0 3.7 1 1 2 4 4 4 0 Nucleoporin Nup120/160 Sec23_trunk PF04811.10 OAP58564.1 - 2.4e-75 253.0 0.0 3.3e-75 252.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAP58564.1 - 4.3e-33 112.8 0.1 8.4e-33 111.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAP58564.1 - 5.8e-30 103.6 0.1 1.4e-29 102.4 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 OAP58564.1 - 4.9e-16 58.0 3.2 9.5e-16 57.0 2.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 OAP58564.1 - 2.6e-10 39.8 0.0 6.3e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 OAP58565.1 - 1.9e-17 62.4 0.1 2.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 OAP58565.1 - 9.2e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Dynamin_N PF00350.18 OAP58566.1 - 1.8e-14 53.9 0.0 5.1e-13 49.1 0.0 3.1 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 OAP58566.1 - 1.2e-05 25.2 0.0 0.0025 17.7 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 OAP58566.1 - 0.00082 19.4 0.0 0.00082 19.4 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 OAP58566.1 - 0.0027 16.9 0.0 0.038 13.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAP58566.1 - 0.0028 16.8 0.1 0.027 13.5 0.0 2.4 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.22 OAP58566.1 - 0.0064 16.7 0.0 0.033 14.4 0.0 2.2 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 OAP58566.1 - 0.083 13.3 0.0 0.4 11.1 0.0 2.3 1 0 0 1 1 1 0 Miro-like protein DASH_Dam1 PF08653.5 OAP58566.1 - 0.17 11.7 0.8 2.8 7.7 0.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 OmpH PF03938.9 OAP58566.1 - 0.23 11.4 16.3 0.61 10.0 3.9 4.0 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 OAP58566.1 - 0.41 9.0 8.2 0.2 10.0 2.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF342) ApoLp-III PF07464.6 OAP58566.1 - 0.44 10.5 0.0 0.44 10.5 0.0 3.8 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Sipho_Gp157 PF05565.6 OAP58566.1 - 0.51 9.9 10.8 0.38 10.3 2.3 3.7 4 0 0 4 4 4 0 Siphovirus Gp157 Syntaxin_2 PF14523.1 OAP58566.1 - 5.3 7.1 10.1 1.2 9.2 1.7 3.5 3 0 0 3 3 3 0 Syntaxin-like protein Abhydrolase_3 PF07859.8 OAP58567.1 - 1.1e-31 110.0 0.6 1.7e-31 109.4 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP58567.1 - 2.9e-05 22.9 0.0 4.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAP58567.1 - 0.0086 15.8 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family gpD PF02925.11 OAP58567.1 - 0.047 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D DUF664 PF04978.7 OAP58567.1 - 0.061 13.5 0.4 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Fungal_trans_2 PF11951.3 OAP58568.1 - 3e-05 22.7 0.5 5.4e-05 21.9 0.4 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain SAPS PF04499.10 OAP58569.1 - 3.8 6.0 8.0 6.2 5.3 5.5 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Glyco_trans_1_2 PF13524.1 OAP58570.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 MFS_1 PF07690.11 OAP58571.1 - 1.2e-22 80.0 56.6 1.6e-16 60.0 19.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP58571.1 - 0.00036 19.2 2.5 0.00036 19.2 1.7 3.5 2 2 0 3 3 3 2 Sugar (and other) transporter DUF3592 PF12158.3 OAP58571.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) NYN PF01936.13 OAP58572.1 - 8.9e-06 26.0 0.0 5.1e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 NYN domain Lactamase_B PF00753.22 OAP58573.1 - 2.2e-17 63.3 3.9 3e-17 62.9 2.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP58573.1 - 0.022 14.3 0.6 0.038 13.5 0.2 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Pex2_Pex12 PF04757.9 OAP58574.1 - 3.9e-39 134.4 5.8 5.8e-39 133.8 4.0 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 OAP58574.1 - 0.0012 18.7 4.6 0.0027 17.5 3.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 OAP58574.1 - 2 8.5 10.0 0.43 10.6 3.2 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.14 OAP58575.1 - 7.6e-13 48.1 0.1 4.4e-12 45.7 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Abhydrolase_6 PF12697.2 OAP58576.1 - 6.2e-22 78.5 0.1 2.1e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP58576.1 - 2.6e-13 49.9 0.0 2.3e-12 46.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 OAP58576.1 - 1.3e-10 41.0 0.0 2.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 OAP58576.1 - 7.8e-07 28.8 0.1 3e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 OAP58576.1 - 0.0005 20.1 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 OAP58576.1 - 0.00063 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ser_hydrolase PF06821.8 OAP58576.1 - 0.0013 18.3 0.0 0.0038 16.8 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 OAP58576.1 - 0.0022 17.4 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 OAP58576.1 - 0.01 15.4 0.0 0.039 13.5 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 OAP58576.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) GATA-N PF05349.7 OAP58576.1 - 0.027 14.6 0.1 0.027 14.6 0.1 1.8 2 0 0 2 2 2 0 GATA-type transcription activator, N-terminal Y_phosphatase3 PF13350.1 OAP58576.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family Hydrolase_4 PF12146.3 OAP58576.1 - 0.14 12.0 0.0 4.6 7.1 0.0 2.5 1 1 1 2 2 2 0 Putative lysophospholipase GatB_N PF02934.10 OAP58577.1 - 1.9e-96 322.3 0.0 2.6e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 OAP58577.1 - 1.4e-20 73.5 0.0 2.2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 GatB domain p450 PF00067.17 OAP58578.1 - 9.3e-68 228.8 0.0 1.1e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arginase PF00491.16 OAP58579.1 - 3.4e-76 256.2 1.1 4.4e-76 255.8 0.8 1.1 1 0 0 1 1 1 1 Arginase family HATPase_c PF02518.21 OAP58580.1 - 2.3e-23 82.0 0.0 4.8e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP58580.1 - 2.6e-22 78.9 0.6 6.2e-22 77.7 0.4 1.7 1 0 0 1 1 1 1 Response regulator receiver domain MHYT PF03707.11 OAP58580.1 - 2.2e-21 75.7 17.1 4.8e-10 39.3 0.3 3.8 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat HisKA PF00512.20 OAP58580.1 - 1.6e-13 50.4 1.9 2.8e-13 49.6 0.5 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 OAP58580.1 - 0.019 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 GHKL domain HATPase_c_2 PF13581.1 OAP58580.1 - 0.028 14.2 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain AIM24 PF01987.12 OAP58581.1 - 3.1e-52 177.1 0.2 3.9e-52 176.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 OAP58582.1 - 6.6e-46 155.0 0.5 1.1e-45 154.3 0.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 OAP58582.1 - 0.087 13.1 0.1 0.3 11.4 0.1 2.0 1 0 0 1 1 1 0 Restriction alleviation protein Lar DNA_RNApol_7kD PF03604.8 OAP58582.1 - 0.11 11.9 1.2 0.27 10.7 0.8 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Arc_trans_TRASH PF08394.5 OAP58582.1 - 2.7 8.2 8.0 1.4 9.1 0.2 3.0 2 1 1 3 3 3 0 Archaeal TRASH domain zf-HYPF PF07503.7 OAP58582.1 - 3.3 7.2 5.3 13 5.3 2.1 2.6 2 1 1 3 3 3 0 HypF finger DNA_binding_1 PF01035.15 OAP58585.1 - 2.4e-23 81.6 0.0 4.6e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain MRC1 PF09444.5 OAP58586.1 - 6e-33 114.2 22.5 6e-33 114.2 15.6 6.8 6 2 2 8 8 8 1 MRC1-like domain AMP-binding PF00501.23 OAP58587.1 - 1.5e-75 254.2 0.1 1.9e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP58587.1 - 2.1e-14 54.1 0.2 4.3e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-CCHC PF00098.18 OAP58588.1 - 3.5e-51 168.7 78.4 2.8e-06 26.9 0.5 10.3 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.1 OAP58588.1 - 5e-06 25.9 43.4 0.041 13.3 0.1 9.2 3 3 7 10 10 10 5 Zinc knuckle zf-CCHC_3 PF13917.1 OAP58588.1 - 0.00021 20.9 64.0 0.26 11.0 0.5 10.0 3 2 7 10 10 10 7 Zinc knuckle zf-CCHC_4 PF14392.1 OAP58588.1 - 0.00031 20.3 65.8 0.0077 15.8 0.6 10.1 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_6 PF15288.1 OAP58588.1 - 0.0061 16.2 3.4 0.0061 16.2 2.4 9.1 6 3 4 10 10 10 3 Zinc knuckle adh_short PF00106.20 OAP58589.1 - 2.8e-09 37.0 0.1 4.6e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58589.1 - 6e-06 26.1 0.0 7.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAP58589.1 - 2.5e-05 24.3 0.1 8e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 OAP58589.1 - 0.0012 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 OAP58589.1 - 0.0087 16.4 0.1 0.027 14.9 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 OAP58589.1 - 0.04 13.3 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP58589.1 - 0.056 13.2 0.9 0.14 12.0 0.2 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-C2H2 PF00096.21 OAP58590.1 - 0.033 14.5 6.9 2.9 8.4 0.7 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP58590.1 - 9.8 6.7 18.0 0.92 9.9 0.3 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger Not3 PF04065.10 OAP58591.1 - 2.8e-79 265.6 25.2 2.8e-79 265.6 17.4 1.7 1 1 1 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 OAP58591.1 - 3.4e-41 140.2 16.2 8.9e-41 138.9 11.3 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 OAP58591.1 - 0.025 14.1 3.8 0.08 12.4 2.7 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Tyr_Deacylase PF02580.11 OAP58592.1 - 1.5e-48 164.4 0.1 1.8e-48 164.2 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FmdA_AmdA PF03069.10 OAP58593.1 - 4.8e-149 496.0 0.0 5.5e-149 495.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Pro-kuma_activ PF09286.6 OAP58595.1 - 2.2e-40 137.9 0.2 3.9e-40 137.1 0.2 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAP58595.1 - 5.9e-11 42.0 0.1 1.1e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Subtilase family 2OG-FeII_Oxy PF03171.15 OAP58596.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Lactamase_B_2 PF12706.2 OAP58598.1 - 4.7e-12 45.8 0.0 1.1e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 OAP58598.1 - 1.6e-08 34.5 0.0 3.6e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 OAP58598.1 - 0.00025 20.7 0.3 0.00065 19.4 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 OAP58598.1 - 0.0055 16.4 0.0 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase NAD_binding_1 PF00175.16 OAP58599.1 - 5.2e-28 97.7 0.0 9.9e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 OAP58599.1 - 5.4e-23 80.9 0.0 1e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 OAP58599.1 - 2.2e-10 40.6 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 OAP58599.1 - 0.002 18.0 0.0 0.0051 16.7 0.0 1.7 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain HMG_box PF00505.14 OAP58600.1 - 3.2e-12 46.5 2.0 7e-12 45.4 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAP58600.1 - 9e-07 29.1 2.1 1.9e-06 28.1 1.4 1.6 1 0 0 1 1 1 1 HMG-box domain EBV-NA3 PF05009.7 OAP58600.1 - 0.46 9.6 2.8 0.78 8.9 1.9 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF4551 PF15087.1 OAP58600.1 - 2 6.6 6.9 2.7 6.2 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Amidohydro_1 PF01979.15 OAP58601.1 - 1.8e-63 215.2 1.2 2.8e-63 214.6 0.8 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 OAP58601.1 - 2.1e-55 186.0 3.7 4.3e-55 185.0 2.5 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 OAP58601.1 - 1.3e-39 134.0 0.2 1.1e-30 105.4 0.0 2.4 1 1 1 2 2 2 2 Urease beta subunit Urease_gamma PF00547.13 OAP58601.1 - 1.7e-20 72.8 0.1 4.2e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.6 OAP58601.1 - 3.9e-06 26.3 0.1 0.00086 18.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP58601.1 - 8.5e-05 22.2 4.2 0.00026 20.7 2.9 1.9 1 0 0 1 1 1 1 Amidohydrolase Abhydrolase_5 PF12695.2 OAP58604.1 - 4.6e-10 39.4 0.0 6.1e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP58604.1 - 6.5e-09 36.0 0.0 2.4e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAP58604.1 - 0.00039 20.0 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP58604.1 - 0.00067 18.9 0.0 0.0013 17.9 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 OAP58604.1 - 0.0095 15.3 0.0 0.085 12.2 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 OAP58604.1 - 0.018 14.2 0.0 0.54 9.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.15 OAP58604.1 - 0.04 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 OAP58604.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 OAP58604.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) SAD_SRA PF02182.12 OAP58605.1 - 1e-16 60.6 0.0 3e-16 59.1 0.0 1.8 1 1 0 1 1 1 1 SAD/SRA domain tRNA-synt_2 PF00152.15 OAP58606.1 - 2.2e-69 233.8 0.0 3.2e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 OAP58606.1 - 2.8e-06 26.7 0.0 0.00079 18.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 OAP58606.1 - 0.00055 19.7 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 OAP58606.1 - 0.0046 16.8 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 OAP58606.1 - 0.0047 16.5 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) zf-Tim10_DDP PF02953.10 OAP58607.1 - 1.4e-24 85.0 2.9 1.7e-24 84.9 2.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CAAP1 PF15335.1 OAP58607.1 - 0.025 14.7 0.1 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 Tom5 PF10642.4 OAP58607.1 - 0.08 12.6 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Peptidase_S76 PF13611.1 OAP58607.1 - 0.13 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 DUF842 PF05811.8 OAP58607.1 - 0.13 11.7 2.0 0.16 11.4 1.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Filament PF00038.16 OAP58608.1 - 0.0022 17.5 2.3 0.0022 17.5 1.6 1.9 3 0 0 3 3 3 1 Intermediate filament protein PG_binding_1 PF01471.13 OAP58608.1 - 0.0064 16.4 0.0 1.7 8.6 0.0 3.1 3 0 0 3 3 3 2 Putative peptidoglycan binding domain Tropomyosin_1 PF12718.2 OAP58608.1 - 0.87 9.4 5.7 3.2 7.6 4.0 2.0 1 1 0 1 1 1 0 Tropomyosin like CLTH PF10607.4 OAP58609.1 - 1.1e-26 93.2 0.1 2.5e-26 92.1 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 OAP58609.1 - 2.8e-17 62.1 4.4 7.6e-17 60.7 3.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 OAP58609.1 - 0.00029 20.1 0.3 0.00049 19.3 0.2 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 OAP58609.1 - 0.002 17.8 2.3 0.0039 16.9 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAP58609.1 - 0.0029 17.3 2.2 0.0054 16.4 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAP58609.1 - 0.11 12.5 3.1 0.2 11.6 2.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UxuA PF03786.8 OAP58609.1 - 0.14 10.6 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) DUF4061 PF13270.1 OAP58609.1 - 0.27 11.3 2.7 0.7 10.0 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) zf-C3HC4_3 PF13920.1 OAP58609.1 - 0.36 10.5 2.3 0.6 9.8 1.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BTB PF00651.26 OAP58610.1 - 3.3e-07 30.2 0.0 6.4e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain GNT-I PF03071.10 OAP58610.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 GNT-I family Skp1_POZ PF03931.10 OAP58610.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain PCI PF01399.22 OAP58611.1 - 1.3e-08 35.0 0.0 4e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_1 PF00515.23 OAP58611.1 - 0.0045 16.5 1.3 0.018 14.6 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP58611.1 - 0.008 16.0 1.0 0.16 11.9 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAP58611.1 - 0.061 12.9 0.2 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 TPR repeat Ribosomal_L18ae PF01775.12 OAP58612.1 - 2.2e-59 198.7 0.4 2.8e-59 198.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Methyltransf_23 PF13489.1 OAP58613.1 - 5e-17 62.0 0.0 7.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP58613.1 - 1.4e-05 25.6 0.0 0.00075 20.0 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP58613.1 - 3.1e-05 24.2 0.1 0.0042 17.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP58613.1 - 7e-05 23.2 0.0 0.0034 17.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP58613.1 - 9.4e-05 22.8 0.0 0.00034 21.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP58613.1 - 0.00014 21.4 0.0 0.00041 19.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP58613.1 - 0.0028 17.6 0.0 0.044 13.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAP58613.1 - 0.0062 15.5 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 OAP58613.1 - 0.018 14.1 0.0 0.18 10.9 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAP58613.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_16 PF00722.16 OAP58614.1 - 2.1e-06 27.1 0.1 3.5e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.27 OAP58614.1 - 7.9e-06 25.5 0.9 0.0022 17.8 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_3 PF13570.1 OAP58614.1 - 4.7e-05 23.5 2.4 2.3 8.6 0.0 4.2 4 0 0 4 4 4 3 PQQ-like domain ABC_tran PF00005.22 OAP58615.1 - 2.8e-46 157.2 0.0 1.5e-24 86.8 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 OAP58615.1 - 3.3e-34 118.5 22.5 5.6e-23 81.7 4.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 OAP58615.1 - 8.2e-16 57.8 3.3 4.8e-06 25.9 0.1 4.7 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP58615.1 - 9.4e-13 48.7 0.0 0.02 14.8 0.0 4.6 3 1 1 4 4 4 4 AAA domain AAA PF00004.24 OAP58615.1 - 4.1e-07 30.2 0.0 0.029 14.5 0.0 3.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 OAP58615.1 - 9.8e-07 28.2 0.1 0.052 13.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 OAP58615.1 - 1.2e-05 25.3 0.1 0.24 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 OAP58615.1 - 2e-05 24.5 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAP58615.1 - 3.1e-05 24.1 2.0 0.1 12.7 0.1 4.0 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 OAP58615.1 - 0.0002 20.8 1.9 2.7 7.3 0.0 4.1 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 OAP58615.1 - 0.00022 20.4 0.1 0.42 9.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAP58615.1 - 0.00022 22.0 0.0 0.24 12.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 OAP58615.1 - 0.00032 21.1 0.1 0.74 10.3 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 OAP58615.1 - 0.00033 20.5 0.0 0.076 12.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 OAP58615.1 - 0.00034 20.4 0.1 0.08 12.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 OAP58615.1 - 0.00048 19.6 3.1 0.21 10.9 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_23 PF13476.1 OAP58615.1 - 0.00064 20.1 0.0 0.83 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 OAP58615.1 - 0.00069 19.3 0.1 0.015 14.9 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 OAP58615.1 - 0.00076 19.2 0.1 6 6.6 0.0 3.8 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 OAP58615.1 - 0.0078 15.1 0.5 0.27 10.0 0.0 3.1 3 1 0 3 3 3 1 NB-ARC domain NACHT PF05729.7 OAP58615.1 - 0.013 15.1 0.5 2.1 8.0 0.1 3.0 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 OAP58615.1 - 0.021 15.0 0.2 19 5.4 0.0 3.4 3 0 0 3 3 3 0 RNA helicase MobB PF03205.9 OAP58615.1 - 0.024 14.3 0.1 3.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 OAP58615.1 - 0.026 14.2 1.8 31 4.2 0.0 3.3 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.20 OAP58615.1 - 0.064 12.7 0.0 6.8 6.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 OAP58615.1 - 0.066 12.7 0.7 3.6 7.0 0.1 2.9 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 OAP58615.1 - 0.077 11.7 0.1 0.56 8.9 0.0 2.3 3 0 0 3 3 2 0 ArgK protein AAA_30 PF13604.1 OAP58615.1 - 0.093 12.3 0.3 32 4.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 OAP58615.1 - 0.12 11.8 1.4 1.5 8.2 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 OAP58615.1 - 0.13 10.8 0.0 0.26 9.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_18 PF13238.1 OAP58615.1 - 0.17 12.1 0.1 14 5.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain KAP_NTPase PF07693.9 OAP58615.1 - 0.22 10.4 0.0 5.9 5.7 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Guanylate_kin PF00625.16 OAP58615.1 - 0.25 10.7 0.1 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase Iso_dh PF00180.15 OAP58616.1 - 9.5e-127 422.7 0.0 1.1e-126 422.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IBR PF01485.16 OAP58617.1 - 9.4e-10 38.2 45.6 8.7e-06 25.5 10.6 4.0 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 OAP58617.1 - 0.0018 17.8 6.3 0.0018 17.8 4.4 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PALP PF00291.20 OAP58618.1 - 2.9e-52 177.8 0.1 3.3e-52 177.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HisG_C PF08029.6 OAP58618.1 - 0.045 13.6 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 HisG, C-terminal domain Peptidase_U35 PF04586.12 OAP58619.1 - 0.053 13.5 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Caudovirus prohead protease HAD_2 PF13419.1 OAP58621.1 - 6.6e-11 42.7 0.0 1e-09 38.8 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP58621.1 - 3.2e-07 30.9 0.0 5.6e-05 23.6 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP58621.1 - 5.5e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 OAP58621.1 - 0.00084 19.5 0.0 0.0019 18.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 OAP58622.1 - 1.8e-43 148.5 0.0 1.4e-39 135.8 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58622.1 - 1.2e-13 50.7 0.0 8.2e-09 34.8 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 OAP58622.1 - 0.00096 18.9 0.2 0.0041 16.8 0.2 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAP58622.1 - 0.0015 17.5 0.0 0.73 8.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 OAP58622.1 - 0.016 14.3 0.1 0.24 10.4 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cnd1_N PF12922.2 OAP58623.1 - 1.9e-56 190.3 0.6 6.2e-56 188.7 0.4 2.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 OAP58623.1 - 1e-54 185.0 3.6 1e-49 168.7 0.1 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 OAP58623.1 - 4.6e-12 46.0 5.5 1.1e-05 25.6 0.0 5.7 4 2 1 5 5 5 2 HEAT repeats Adaptin_N PF01602.15 OAP58623.1 - 2.2e-07 29.5 5.5 0.0013 17.1 0.1 3.6 4 1 0 4 4 4 2 Adaptin N terminal region HEAT PF02985.17 OAP58623.1 - 2.3e-07 30.3 12.5 0.16 12.0 0.0 7.2 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 OAP58623.1 - 2.7e-07 30.8 5.7 0.023 15.1 0.0 6.2 7 0 0 7 7 7 2 HEAT-like repeat DUF2435 PF10363.4 OAP58623.1 - 0.00028 20.7 0.1 0.66 9.9 0.1 4.0 2 1 0 3 3 3 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 OAP58623.1 - 0.0067 15.4 6.4 0.11 11.3 1.7 4.0 2 2 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain SKG6 PF08693.5 OAP58625.1 - 0.0087 15.3 0.1 0.025 13.9 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SOG2 PF10428.4 OAP58625.1 - 0.04 12.5 3.5 0.043 12.4 2.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cytomega_TRL10 PF06084.6 OAP58625.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.2 3 0 0 3 3 3 0 Cytomegalovirus TRL10 protein Med3 PF11593.3 OAP58625.1 - 0.35 10.0 10.6 0.46 9.6 7.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF822 PF05687.8 OAP58625.1 - 0.45 10.8 6.4 0.93 9.8 4.4 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) MCLC PF05934.6 OAP58625.1 - 1.9 6.6 5.9 2.6 6.2 4.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF515 PF04415.7 OAP58625.1 - 3.6 5.7 9.7 5 5.2 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Fungal_trans PF04082.13 OAP58626.1 - 1.1e-21 76.8 0.5 1.1e-21 76.8 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 OAP58626.1 - 7e-06 26.0 8.2 0.017 15.3 0.6 3.1 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP58626.1 - 0.019 15.2 1.7 0.019 15.2 1.2 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Oxysterol_BP PF01237.13 OAP58627.1 - 9.9e-54 182.1 0.0 8.1e-53 179.1 0.0 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein Aldedh PF00171.17 OAP58628.1 - 9.5e-83 278.0 0.0 1.2e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Trehalase PF01204.13 OAP58629.1 - 1.3e-179 598.1 0.0 1.8e-179 597.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 OAP58629.1 - 1.9e-13 49.4 1.6 3.3e-13 48.6 1.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain FYVE PF01363.16 OAP58629.1 - 0.00099 18.9 4.6 0.00099 18.9 3.2 2.4 4 0 0 4 4 4 1 FYVE zinc finger RE_TaqI PF09573.5 OAP58629.1 - 0.062 12.4 1.7 0.11 11.5 0.6 1.8 1 1 1 2 2 2 0 TaqI restriction endonuclease ICL PF00463.16 OAP58630.1 - 1.9e-284 943.7 4.5 2.2e-284 943.5 3.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 OAP58630.1 - 4.5e-12 45.7 0.1 4.1e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase adh_short PF00106.20 OAP58631.1 - 1.2e-25 90.3 0.1 2.2e-25 89.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP58631.1 - 3.4e-10 39.8 0.1 5.8e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP58631.1 - 1.6e-05 24.7 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 OAP58631.1 - 0.002 16.8 0.0 0.0026 16.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAP58631.1 - 0.09 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CMV_US PF08001.6 OAP58633.1 - 0.039 13.0 0.4 0.046 12.7 0.3 1.2 1 0 0 1 1 1 0 CMV US DUF4654 PF15547.1 OAP58633.1 - 3.1 8.1 5.9 7.1 6.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4654) MRP-L20 PF12824.2 OAP58635.1 - 1e-49 168.6 7.5 1.2e-49 168.4 5.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 OAP58635.1 - 0.0025 17.6 0.1 0.0038 17.0 0.1 1.4 1 0 0 1 1 1 1 Neugrin PET PF06297.9 OAP58635.1 - 0.058 13.0 0.5 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 PET Domain Peptidase_M20 PF01546.23 OAP58636.1 - 4.1e-31 107.9 0.0 6.1e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAP58636.1 - 6.1e-14 51.7 0.0 9.9e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PCMT PF01135.14 OAP58637.1 - 1.1e-65 221.1 0.0 1.2e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 OAP58637.1 - 6.9e-10 39.4 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP58637.1 - 1.6e-09 37.5 0.2 2.5e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 OAP58637.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP58637.1 - 6.6e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP58637.1 - 0.00019 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 OAP58637.1 - 0.00021 21.0 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP58637.1 - 0.0011 19.3 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP58637.1 - 0.0028 18.0 0.0 0.0042 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP58637.1 - 0.0056 15.8 0.0 0.0075 15.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 OAP58637.1 - 0.0077 16.2 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 OAP58637.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 OAP58637.1 - 0.026 13.5 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 OAP58637.1 - 0.034 14.4 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 OAP58637.1 - 0.062 14.1 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 OAP58637.1 - 0.097 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase EF-hand_1 PF00036.27 OAP58637.1 - 0.2 11.0 2.1 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.1 OAP58637.1 - 5.6 6.4 5.9 0.65 9.4 0.2 2.3 2 0 0 2 2 2 0 EF hand Cys_Met_Meta_PP PF01053.15 OAP58638.1 - 8.2e-34 116.5 0.0 1.1e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAP58638.1 - 0.081 11.8 0.0 0.25 10.2 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II Nrap PF03813.9 OAP58639.1 - 1.4e-269 896.7 0.0 1.7e-269 896.4 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Mito_carr PF00153.22 OAP58640.1 - 3.5e-56 186.9 1.3 2.9e-21 74.9 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein SMC_N PF02463.14 OAP58641.1 - 1.2e-27 96.5 0.1 1.7e-27 96.0 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAP58641.1 - 1.1e-15 58.5 16.9 1.1e-15 58.5 11.7 4.3 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.1 OAP58641.1 - 6.7e-08 31.9 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 OAP58641.1 - 5.8e-07 29.7 0.7 0.00021 21.3 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAP58641.1 - 0.00054 19.4 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Lectin_N PF03954.9 OAP58641.1 - 0.0033 16.8 3.7 0.065 12.6 0.4 3.5 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain AAA_13 PF13166.1 OAP58641.1 - 0.088 11.2 49.7 0.032 12.7 7.6 5.0 3 2 1 4 4 4 0 AAA domain ABC_tran PF00005.22 OAP58641.1 - 0.13 12.5 7.8 0.8 9.9 0.2 4.0 3 2 0 3 3 3 0 ABC transporter Reo_sigmaC PF04582.7 OAP58641.1 - 0.2 10.7 7.9 1.5 7.9 0.9 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein FliJ PF02050.11 OAP58641.1 - 4.4 7.3 63.6 0.082 12.9 6.9 6.6 4 2 1 6 6 6 0 Flagellar FliJ protein DEAD PF00270.24 OAP58642.1 - 5.5e-41 139.8 0.0 7.8e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP58642.1 - 3.7e-24 84.3 0.1 8e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4146 PF13652.1 OAP58642.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4146) CMS1 PF14617.1 OAP58642.1 - 0.14 11.1 0.0 0.33 9.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FoP_duplication PF13865.1 OAP58642.1 - 2.8 8.4 8.7 6.4 7.3 6.0 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 API5 PF05918.6 OAP58642.1 - 3.4 6.0 15.1 5.2 5.4 10.5 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1918 PF08940.6 OAP58643.1 - 0.0027 16.9 0.2 1.3 8.3 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.16 OAP58644.1 - 2.4e-48 164.1 0.0 3.1e-47 160.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 YccV-like PF08755.6 OAP58645.1 - 1.3e-24 85.9 0.0 2.6e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 OAP58645.1 - 2.2e-12 46.7 0.0 4e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 OAP58645.1 - 1.4e-11 43.8 0.0 3.4e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP58645.1 - 2.7e-09 36.4 0.0 2.9e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 F-box domain Herpes_capsid PF06112.6 OAP58646.1 - 3 7.8 8.3 0.86 9.6 3.9 1.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Rhodanese PF00581.15 OAP58647.1 - 1.8e-06 28.2 0.0 4.1e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain DnaJ PF00226.26 OAP58649.1 - 1.8e-26 91.6 0.5 7.6e-26 89.6 0.4 2.2 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 OAP58649.1 - 3.4e-12 46.1 14.5 2.1e-10 40.4 2.6 3.4 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP58649.1 - 2.6e-10 40.1 12.4 2.6e-09 36.9 1.4 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAP58649.1 - 1.7e-09 37.6 5.6 0.00064 19.8 0.8 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 OAP58649.1 - 3e-05 24.1 8.2 0.022 15.0 0.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP58649.1 - 5.6e-05 23.1 4.4 0.11 12.9 0.4 3.1 2 1 1 3 3 3 2 C2H2-type zinc finger RPT PF13446.1 OAP58649.1 - 0.09 12.2 0.0 0.09 12.2 0.0 2.6 4 0 0 4 4 4 0 A repeated domain in UCH-protein CpXC PF14353.1 OAP58649.1 - 0.13 12.2 5.5 1.8 8.5 0.1 3.3 3 1 0 3 3 3 0 CpXC protein Cuticle_3 PF11018.3 OAP58649.1 - 0.42 10.7 5.1 0.069 13.2 0.4 1.9 2 0 0 2 2 2 0 Pupal cuticle protein C1 zf-H2C2_2 PF13465.1 OAP58649.1 - 0.56 10.6 2.4 3.7 8.0 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.8 OAP58649.1 - 0.91 9.2 5.2 0.78 9.4 0.7 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like SPX PF03105.14 OAP58650.1 - 3e-41 142.0 3.5 4.3e-41 141.5 2.4 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 OAP58650.1 - 1.3e-07 31.3 9.1 1.3e-07 31.3 6.3 2.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAP58650.1 - 5.8e-07 29.0 7.5 1.1e-06 28.1 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP58650.1 - 3.4e-06 26.5 9.7 3.4e-06 26.5 6.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP58650.1 - 5.8e-06 26.2 12.0 1.4e-05 25.0 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP58650.1 - 2.4e-05 23.9 7.5 6.8e-05 22.5 5.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAP58650.1 - 7.6e-05 22.4 13.4 7.9e-05 22.4 7.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 OAP58650.1 - 0.0024 17.5 3.5 0.0024 17.5 2.4 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_4 PF14570.1 OAP58650.1 - 0.096 12.2 7.7 0.029 13.9 2.8 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 OAP58650.1 - 0.11 12.3 2.5 0.22 11.3 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 OAP58650.1 - 0.33 10.8 3.2 0.77 9.6 2.2 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain F-112 PF09645.5 OAP58650.1 - 0.48 10.3 4.1 0.24 11.2 0.2 2.4 2 0 0 2 2 2 0 F-112 protein NOB1_Zn_bind PF08772.6 OAP58650.1 - 1.1 9.0 4.3 0.69 9.7 1.3 1.9 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-P11 PF03854.9 OAP58650.1 - 1.6 8.2 8.8 1.3 8.5 2.7 2.2 1 1 1 2 2 2 0 P-11 zinc finger zf-rbx1 PF12678.2 OAP58650.1 - 3.4 7.8 7.3 11 6.1 5.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger Epimerase PF01370.16 OAP58652.1 - 4e-12 46.0 0.0 7.8e-12 45.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP58652.1 - 5.9e-08 32.9 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP58652.1 - 7.1e-08 31.9 0.0 0.0088 15.3 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family RmlD_sub_bind PF04321.12 OAP58652.1 - 0.00023 20.1 0.0 0.057 12.2 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_2 PF03446.10 OAP58652.1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 OAP58652.1 - 0.053 13.4 0.3 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase YceG PF02618.11 OAP58653.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 YceG-like family NAD_binding_2 PF03446.10 OAP58654.1 - 1.5e-36 125.7 0.2 2e-36 125.2 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP58654.1 - 8.4e-30 103.3 0.0 1.5e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 OAP58654.1 - 4.3e-08 32.5 0.0 6.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAP58654.1 - 1.3e-05 25.5 0.2 2.9e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 OAP58654.1 - 0.0014 17.9 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Rossmann-like PF10727.4 OAP58654.1 - 0.0055 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Rossmann-like domain SUFU PF05076.8 OAP58654.1 - 0.0077 15.8 0.0 0.079 12.5 0.0 2.1 1 1 1 2 2 2 1 Suppressor of fused protein (SUFU) 3HCDH_N PF02737.13 OAP58654.1 - 0.025 14.2 0.0 0.082 12.5 0.0 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 OAP58654.1 - 0.071 13.1 0.0 0.18 11.7 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 OAP58655.1 - 6.3e-14 51.7 0.2 5e-13 48.8 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 OAP58655.1 - 8.2e-06 24.9 0.2 1.3e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP58655.1 - 4.5e-05 23.4 0.2 0.0001 22.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP58655.1 - 4.9e-05 22.4 0.5 0.0008 18.4 0.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP58655.1 - 0.00012 22.0 0.2 0.00042 20.2 0.2 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP58655.1 - 0.00025 20.0 0.3 0.00045 19.2 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 OAP58655.1 - 0.0036 17.6 0.6 0.25 11.7 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP58655.1 - 0.03 13.4 0.2 0.048 12.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP58655.1 - 0.06 11.8 0.3 0.13 10.7 0.2 1.5 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.13 OAP58655.1 - 0.1 12.2 0.2 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 OAP58655.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_4 PF01565.18 OAP58656.1 - 7e-31 106.5 0.0 1.1e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 OAP58656.1 - 7.4e-20 71.3 0.0 1.1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Fungal_trans PF04082.13 OAP58657.1 - 3.5e-07 29.3 0.0 5.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.13 OAP58658.1 - 9.7e-110 366.7 0.0 1.3e-109 366.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAP58658.1 - 4.1e-20 71.3 0.0 9.5e-20 70.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAP58658.1 - 0.00092 18.2 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAP58658.1 - 0.092 11.6 0.0 0.24 10.2 0.0 1.5 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ApbA PF02558.11 OAP58659.1 - 6.8e-33 113.2 0.0 8.8e-33 112.8 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 OAP58659.1 - 5.1e-27 94.3 0.1 7.7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 OAP58659.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.20 OAP58660.1 - 8.9e-28 97.2 3.7 1.3e-27 96.8 2.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58660.1 - 1.7e-23 83.6 0.0 2e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58660.1 - 6.9e-11 42.1 3.2 1.3e-10 41.1 2.2 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP58660.1 - 0.001 18.7 0.8 0.0022 17.7 0.6 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP58660.1 - 0.0012 18.3 0.3 0.0014 18.1 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP58660.1 - 0.0026 17.7 2.7 0.014 15.4 1.5 2.4 1 1 1 2 2 2 1 NADH(P)-binding Glyco_transf_5 PF08323.6 OAP58660.1 - 0.012 15.1 0.0 0.05 13.0 0.0 1.9 2 1 0 2 2 2 0 Starch synthase catalytic domain ApbA PF02558.11 OAP58660.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MR_MLE_C PF13378.1 OAP58661.1 - 4.9e-32 110.1 0.1 8.6e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 OAP58661.1 - 2.4e-20 72.6 0.0 5.9e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 OAP58661.1 - 8.6e-10 39.0 0.0 2.1e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Fungal_trans PF04082.13 OAP58662.1 - 1e-57 194.9 0.0 1.5e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP58662.1 - 0.00088 19.4 10.1 0.007 16.6 0.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP58662.1 - 0.0017 18.5 9.9 0.0069 16.6 0.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP58662.1 - 0.0035 17.5 5.4 0.039 14.2 1.4 2.8 2 0 0 2 2 2 1 Zinc-finger double domain Aldedh PF00171.17 OAP58663.1 - 6.7e-146 486.2 0.0 7.7e-146 486.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP58663.1 - 0.067 11.9 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) AA_permease_2 PF13520.1 OAP58664.1 - 3.1e-43 147.9 57.7 3.3e-42 144.5 40.0 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP58664.1 - 2.5e-24 85.4 41.1 3.7e-24 84.9 28.5 1.2 1 0 0 1 1 1 1 Amino acid permease Serglycin PF04360.7 OAP58665.1 - 0.0025 17.5 0.4 0.004 16.8 0.2 1.4 1 0 0 1 1 1 1 Serglycin Acetyltransf_7 PF13508.1 OAP58666.1 - 9.1e-10 38.5 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP58666.1 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP58666.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP58666.1 - 0.0013 18.6 0.0 0.006 16.4 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP58666.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.11 OAP58667.1 - 4.3e-34 117.7 26.7 4.3e-34 117.7 18.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAP58667.1 - 5.1e-05 21.8 10.8 8.1e-05 21.1 5.7 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein Fungal_trans_2 PF11951.3 OAP58668.1 - 1.9e-09 36.6 0.0 3.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP58669.1 - 7.2e-38 130.1 32.0 1e-37 129.7 22.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP58669.1 - 0.0026 17.5 0.2 0.013 15.2 0.1 2.3 1 0 0 1 1 1 1 MFS_1 like family NAD_binding_11 PF14833.1 OAP58670.1 - 1.4e-30 105.8 0.0 2.4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 OAP58670.1 - 1.1e-28 100.1 0.0 1.6e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAP58670.1 - 0.0028 18.0 0.0 0.0065 16.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 OAP58670.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ABM PF03992.11 OAP58671.1 - 5.5e-13 48.7 0.4 9.5e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Methyltransf_23 PF13489.1 OAP58672.1 - 7.5e-13 48.5 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP58672.1 - 3.1e-09 37.3 0.2 8.3e-08 32.7 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP58672.1 - 2.8e-06 27.7 0.0 6.7e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP58672.1 - 1.4e-05 24.7 0.0 0.0076 15.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 OAP58672.1 - 4.7e-05 23.7 0.0 0.00073 19.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP58672.1 - 9.4e-05 22.7 0.0 0.0017 18.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAP58672.1 - 0.0017 17.4 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 OAP58672.1 - 0.0065 16.4 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_PK PF05891.7 OAP58672.1 - 0.064 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_26 PF13659.1 OAP58672.1 - 0.071 13.1 0.0 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 OAP58672.1 - 0.079 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain CMAS PF02353.15 OAP58672.1 - 0.092 11.8 0.0 0.3 10.1 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 OAP58672.1 - 0.13 11.3 0.0 0.5 9.4 0.0 1.9 3 0 0 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) HD PF01966.17 OAP58673.1 - 8.6e-07 29.0 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 HD domain CBM_1 PF00734.13 OAP58674.1 - 1.7e-08 33.9 8.1 5.8e-08 32.2 5.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DPBB_1 PF03330.13 OAP58674.1 - 0.00026 20.9 0.7 0.00047 20.1 0.1 1.7 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Retinal PF15449.1 OAP58674.1 - 1.3 6.5 13.6 1.5 6.3 9.4 1.0 1 0 0 1 1 1 0 Retinal protein FAD_binding_3 PF01494.14 OAP58675.1 - 2.1e-14 53.3 0.0 4.7e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP58675.1 - 1.7e-05 23.9 0.4 0.011 14.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAP58675.1 - 7.7e-05 21.5 0.8 0.0085 14.7 0.1 2.4 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 OAP58675.1 - 0.00088 19.2 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP58675.1 - 0.0027 16.6 0.3 1.4 7.7 0.1 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP58675.1 - 0.044 13.8 0.0 0.23 11.5 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP58675.1 - 0.05 14.0 0.4 3 8.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase G-patch PF01585.18 OAP58676.1 - 1e-09 38.0 1.2 3.8e-09 36.1 0.8 2.1 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 OAP58676.1 - 4.9e-08 32.5 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 OAP58676.1 - 0.0025 17.5 1.2 0.016 15.0 0.8 2.5 1 0 0 1 1 1 1 DExH-box splicing factor binding site IgaA PF07095.6 OAP58676.1 - 0.33 8.6 0.0 0.48 8.1 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Peptidase_C54 PF03416.14 OAP58677.1 - 5.7e-95 317.6 0.0 7.7e-95 317.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 ATPgrasp_Ter PF15632.1 OAP58677.1 - 0.032 12.9 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Histone PF00125.19 OAP58678.1 - 2.4e-22 78.8 0.2 3.3e-22 78.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAP58678.1 - 4.2e-05 23.5 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 OAP58678.1 - 0.00023 21.3 0.0 0.00038 20.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 OAP58678.1 - 0.031 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 OAP58678.1 - 0.07 13.6 0.2 0.097 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.19 OAP58679.1 - 8.1e-26 89.9 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAP58679.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.10 OAP58680.1 - 8.3e-09 35.1 2.0 1.4e-08 34.3 1.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAP58680.1 - 2.6e-06 27.5 1.0 4.7e-06 26.7 0.7 1.4 1 0 0 1 1 1 1 Complex1_LYR-like 2-oxoacid_dh PF00198.18 OAP58681.1 - 9.4e-80 267.1 0.3 1.2e-79 266.8 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAP58681.1 - 1.2e-17 63.2 1.3 2.7e-17 62.1 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 OAP58681.1 - 4.6e-06 26.0 4.6 3.2e-05 23.2 0.9 2.4 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 OAP58681.1 - 0.00019 21.0 0.5 0.46 10.2 0.0 2.9 1 1 1 2 2 2 2 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 OAP58681.1 - 0.00025 20.6 0.3 0.0079 15.8 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 OAP58681.1 - 0.0024 18.1 0.3 0.21 11.9 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein Peptidase_M23 PF01551.17 OAP58681.1 - 0.02 14.9 0.3 3.9 7.5 0.1 2.6 1 1 1 2 2 2 0 Peptidase family M23 DUF605 PF04652.11 OAP58681.1 - 0.029 13.7 10.4 0.036 13.4 7.2 1.1 1 0 0 1 1 1 0 Vta1 like GCV_H PF01597.14 OAP58681.1 - 0.032 13.9 0.6 0.095 12.3 0.3 1.8 1 1 0 1 1 1 0 Glycine cleavage H-protein HlyD PF00529.15 OAP58681.1 - 0.049 12.9 0.3 0.09 12.0 0.1 1.5 2 0 0 2 2 2 0 HlyD family secretion protein COesterase PF00135.23 OAP58682.1 - 7.5e-59 199.8 0.0 2.7e-58 198.0 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP58682.1 - 1.8e-05 24.4 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sugar_tr PF00083.19 OAP58683.1 - 2.2e-98 329.7 23.5 2.6e-98 329.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58683.1 - 7.8e-21 74.1 39.1 1.3e-20 73.3 17.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP58683.1 - 0.022 13.1 30.4 0.12 10.7 2.1 3.3 2 1 1 3 3 3 0 MFS/sugar transport protein Acetyltransf_13 PF13880.1 OAP58685.1 - 1e-26 92.4 0.0 2e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 OAP58685.1 - 2.7e-12 46.0 0.1 4.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 OAP58685.1 - 0.038 14.0 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP58685.1 - 0.18 11.9 0.0 0.48 10.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 OAP58686.1 - 4.4e-39 134.1 19.6 1.8e-38 132.1 13.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily PLDc PF00614.17 OAP58688.1 - 1.7e-17 62.5 1.2 7.9e-09 35.0 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 OAP58688.1 - 1.2e-13 50.8 0.1 6.8e-08 32.3 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain PX PF00787.19 OAP58688.1 - 1.2e-11 44.3 0.0 4.1e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 PX domain ApbA PF02558.11 OAP58689.1 - 7.5e-18 64.4 0.0 1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 OAP58689.1 - 1.7e-07 30.5 0.0 2.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP58689.1 - 1e-06 29.0 0.2 1.9e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP58689.1 - 4.9e-06 26.5 0.0 7.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 OAP58689.1 - 6.5e-06 26.4 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 OAP58689.1 - 1.5e-05 24.8 0.0 6.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 OAP58689.1 - 2.9e-05 24.2 0.0 7.2e-05 22.9 0.0 1.7 2 0 0 2 2 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 OAP58689.1 - 0.00025 20.7 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 OAP58689.1 - 0.00028 20.8 0.6 0.00055 19.9 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.10 OAP58689.1 - 0.00029 20.7 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.14 OAP58689.1 - 0.00085 18.4 0.5 0.0012 17.9 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP58689.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP58689.1 - 0.0013 18.7 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 OAP58689.1 - 0.0051 16.8 0.1 0.0078 16.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 OAP58689.1 - 0.006 15.9 0.1 0.011 15.0 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 OAP58689.1 - 0.011 14.5 0.4 0.021 13.6 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 OAP58689.1 - 0.012 15.4 0.3 0.021 14.6 0.2 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 OAP58689.1 - 0.017 13.6 0.4 0.039 12.4 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein IlvN PF07991.7 OAP58689.1 - 0.02 14.2 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Rossmann-like PF10727.4 OAP58689.1 - 0.046 13.4 0.7 0.15 11.7 0.2 2.1 2 1 0 2 2 2 0 Rossmann-like domain GIDA PF01134.17 OAP58689.1 - 0.066 12.0 0.9 0.087 11.6 0.6 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.1 OAP58689.1 - 0.067 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.13 OAP58689.1 - 0.073 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 OAP58689.1 - 0.086 12.6 0.2 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding DND1_DSRM PF14709.1 OAP58689.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Lycopene_cycl PF05834.7 OAP58689.1 - 0.14 11.0 0.3 0.21 10.4 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ELFV_dehydrog PF00208.16 OAP58689.1 - 0.16 11.4 0.1 0.32 10.5 0.0 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zn_clus PF00172.13 OAP58690.1 - 2.6e-05 24.0 3.1 6e-05 22.8 2.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP58690.1 - 0.16 10.5 4.9 0.089 11.3 0.4 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Ras PF00071.17 OAP58691.1 - 2.8e-38 130.8 0.0 1.3e-36 125.4 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 OAP58691.1 - 5.4e-12 46.2 0.0 1.1e-11 45.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 OAP58691.1 - 0.00047 20.0 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 OAP58691.1 - 0.00049 19.3 0.1 0.0031 16.7 0.0 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAP58691.1 - 0.0094 15.4 0.0 0.34 10.3 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PRK PF00485.13 OAP58691.1 - 0.054 13.0 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF3176 PF11374.3 OAP58692.1 - 1.1e-30 105.8 0.6 3.8e-30 104.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) FtsX PF02687.16 OAP58692.1 - 1.8 8.3 9.8 2.6 7.8 0.1 3.6 4 0 0 4 4 4 0 FtsX-like permease family PAS_9 PF13426.1 OAP58693.1 - 1.2e-27 96.2 0.0 2.4e-16 59.9 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 OAP58693.1 - 1.4e-17 63.5 0.0 6.5e-11 42.1 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 OAP58693.1 - 3.9e-14 51.6 8.2 3.9e-14 51.6 5.7 2.0 2 0 0 2 2 2 1 GATA zinc finger PAS_11 PF14598.1 OAP58693.1 - 1.5e-13 50.7 0.0 1.5e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 OAP58693.1 - 3e-13 49.5 0.0 0.00065 19.4 0.0 4.1 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.5 OAP58693.1 - 1.1e-07 31.9 0.0 0.037 14.0 0.0 3.7 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 OAP58693.1 - 0.09 12.6 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 PAS domain HUN PF08729.5 OAP58694.1 - 1.8e-13 50.1 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 OAP58695.1 - 5.5e-28 96.6 0.0 1.3e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 OAP58695.1 - 4.1e-13 48.6 7.2 8.6e-13 47.6 5.0 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal Pyr_redox_3 PF13738.1 OAP58696.1 - 1.9e-25 90.1 0.0 4.8e-24 85.5 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP58696.1 - 4.5e-13 48.2 0.4 1.7e-12 46.3 0.0 2.1 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP58696.1 - 1.8e-07 30.4 0.3 6.8e-06 25.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP58696.1 - 8e-07 29.0 0.0 2.8e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP58696.1 - 0.017 15.0 0.0 0.98 9.2 0.0 2.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 OAP58697.1 - 3.5e-25 88.8 0.1 5.2e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58697.1 - 2.2e-16 60.3 0.0 2.8e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 OAP58697.1 - 1.4e-09 37.5 0.0 7.6e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 OAP58697.1 - 7.9e-06 25.6 0.1 1.9e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 OAP58697.1 - 0.013 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 OAP58697.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_S68 PF10461.4 OAP58697.1 - 0.37 10.5 1.7 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase S68 Proteasome PF00227.21 OAP58699.1 - 8.8e-49 165.3 0.0 1.2e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAP58699.1 - 5.3e-13 48.0 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 OAP58699.1 - 0.11 11.9 0.5 0.11 11.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 OAP58700.1 - 3.3e-23 81.0 0.1 7e-23 79.9 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Pol_alpha_B_N PF08418.5 OAP58700.1 - 9.3 5.7 28.0 0.31 10.5 3.7 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Asp PF00026.18 OAP58701.1 - 2e-104 349.2 0.0 2.4e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAP58701.1 - 6.7e-10 39.1 0.0 1.8e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAP58701.1 - 4.1e-05 23.9 0.1 0.71 10.4 0.0 3.0 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 OAP58701.1 - 6.4e-05 22.5 0.0 0.00056 19.4 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal NIF PF03031.13 OAP58702.1 - 4.4e-28 97.9 0.0 9.2e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 OAP58702.1 - 9e-14 51.0 0.2 1.7e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 OAP58702.1 - 1.7e-10 40.8 0.0 3.7e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain tRNA-synt_2 PF00152.15 OAP58705.1 - 3.5e-50 170.6 0.0 4.7e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 OAP58705.1 - 0.0055 15.9 0.3 2.5 7.2 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-like PF12869.2 OAP58705.1 - 0.0061 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 tRNA_anti-like SAP30_Sin3_bdg PF13867.1 OAP58705.1 - 0.085 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2434 PF10361.4 OAP58706.1 - 5.8e-95 317.7 3.2 1e-94 316.9 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2434) DUF4149 PF13664.1 OAP58706.1 - 0.011 15.7 4.1 0.084 12.9 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Gti1_Pac2 PF09729.4 OAP58707.1 - 3.5e-50 170.1 0.8 9.2e-49 165.5 0.6 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family HET PF06985.6 OAP58708.1 - 3.3e-31 108.2 0.4 6.3e-31 107.3 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SBP_bac_8 PF13416.1 OAP58708.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein LVIVD PF08309.6 OAP58708.1 - 0.16 10.9 0.1 0.38 9.7 0.0 1.5 1 0 0 1 1 1 0 LVIVD repeat p450 PF00067.17 OAP58709.1 - 1.8e-30 105.9 0.0 2.1e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Spc97_Spc98 PF04130.8 OAP58710.1 - 1.4e-114 383.3 0.6 2.4e-114 382.6 0.4 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family BSP_II PF05432.6 OAP58710.1 - 0.11 11.7 4.2 0.18 11.0 2.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MFS_1 PF07690.11 OAP58711.1 - 7e-20 71.0 53.0 4.7e-19 68.3 32.1 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP58711.1 - 6.7e-05 21.2 25.0 0.00012 20.4 17.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cupin_2 PF07883.6 OAP58712.1 - 2.4e-08 33.3 0.1 0.00011 21.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 OAP58712.1 - 1.1e-05 24.9 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 OAP58712.1 - 6.7e-05 22.1 0.1 0.00017 20.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 OAP58712.1 - 0.0087 15.6 1.5 0.03 13.9 0.7 2.1 1 1 0 1 1 1 1 Cupin DHHA1 PF02272.14 OAP58712.1 - 2.3 7.9 4.4 31 4.3 0.6 2.8 2 1 0 2 2 2 0 DHHA1 domain Pmp3 PF01679.12 OAP58713.1 - 1.2e-20 72.8 8.2 1.9e-20 72.2 5.7 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RseC_MucC PF04246.7 OAP58713.1 - 0.094 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC TPPK_C PF12555.3 OAP58713.1 - 0.12 12.1 2.0 0.27 10.9 1.4 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal FRG1 PF06229.7 OAP58714.1 - 2e-42 144.8 1.0 3.3e-42 144.1 0.7 1.3 1 0 0 1 1 1 1 FRG1-like family zf-RING_2 PF13639.1 OAP58715.1 - 3.5e-14 52.3 4.9 6.1e-14 51.5 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP58715.1 - 1.3e-07 31.4 5.0 2.4e-07 30.6 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP58715.1 - 2.8e-06 26.8 3.9 4.9e-06 26.1 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAP58715.1 - 3.2e-06 27.1 0.6 6.6e-06 26.1 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 OAP58715.1 - 3.9e-06 26.4 3.3 6.2e-06 25.8 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAP58715.1 - 2.3e-05 23.9 2.2 3.7e-05 23.3 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAP58715.1 - 0.0027 17.5 0.4 0.0057 16.4 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 OAP58715.1 - 0.0067 16.1 1.1 0.012 15.3 0.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger DUF1049 PF06305.6 OAP58715.1 - 0.019 14.4 1.0 0.019 14.4 0.7 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1049) zf-Nse PF11789.3 OAP58715.1 - 0.023 14.2 3.2 0.048 13.1 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 OAP58715.1 - 0.07 13.0 4.7 0.16 11.8 3.3 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 OAP58715.1 - 0.084 12.5 2.3 0.14 11.8 1.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 OAP58715.1 - 0.11 12.1 3.3 0.19 11.3 2.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TMEM154 PF15102.1 OAP58715.1 - 0.11 12.1 0.4 0.23 11.1 0.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family ATP-synt_8 PF00895.15 OAP58715.1 - 0.15 12.3 0.7 0.35 11.1 0.5 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 Baculo_11_kDa PF06143.6 OAP58715.1 - 0.2 11.0 1.6 0.39 10.1 1.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family FANCL_C PF11793.3 OAP58715.1 - 0.2 11.6 1.8 0.55 10.2 1.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 OAP58715.1 - 0.29 10.9 1.7 0.52 10.0 0.4 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Ada3 PF10198.4 OAP58716.1 - 2.8e-39 133.8 0.0 2.8e-39 133.8 0.0 2.3 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 CSTF2_hinge PF14327.1 OAP58716.1 - 0.0033 17.4 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 DUF913 PF06025.7 OAP58716.1 - 4.2 6.0 6.2 7.4 5.2 4.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Herpes_UL25 PF01499.11 OAP58716.1 - 5.5 5.1 6.4 10 4.3 4.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Pkinase PF00069.20 OAP58717.1 - 1.5e-17 63.5 0.0 4.7e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58717.1 - 2.9e-10 39.6 0.0 1.2e-08 34.3 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase p450 PF00067.17 OAP58718.1 - 9.3e-48 162.8 0.0 1.3e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Bap31 PF05529.7 OAP58719.1 - 0.023 14.1 1.6 0.041 13.3 1.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like E7 PF00527.13 OAP58719.1 - 0.044 13.9 2.3 0.044 13.9 0.8 1.6 1 1 1 2 2 2 0 E7 protein, Early protein YgaB PF14182.1 OAP58719.1 - 0.17 12.1 1.8 0.33 11.2 1.2 1.4 1 0 0 1 1 1 0 YgaB-like protein COQ7 PF03232.8 OAP58720.1 - 2.3e-64 215.9 0.0 2.8e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 OAP58720.1 - 3.4e-05 24.1 0.1 0.00014 22.1 0.0 1.9 1 1 1 2 2 2 1 Rubrerythrin Herpes_UL6 PF01763.11 OAP58720.1 - 0.032 12.4 0.0 0.043 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1817 PF08847.6 OAP58720.1 - 0.084 12.4 0.0 0.22 11.0 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1817) Plus-3 PF03126.13 OAP58721.1 - 3.7e-25 88.0 0.0 1.4e-24 86.2 0.0 2.0 2 0 0 2 2 2 1 Plus-3 domain Aldo_ket_red PF00248.16 OAP58723.1 - 2.6e-51 174.1 0.0 3.2e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pro_isomerase PF00160.16 OAP58727.1 - 3.2e-33 115.1 0.1 5.6e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 OAP58727.1 - 1.3e-14 53.5 7.0 8.5e-07 28.5 0.9 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAP58727.1 - 3.5e-09 35.8 9.6 2.7e-07 29.9 0.3 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAP58727.1 - 8.6e-09 34.6 7.6 1.6e-06 27.4 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAP58727.1 - 2.2e-06 27.4 6.3 1.5e-05 24.8 0.5 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP58727.1 - 3.7e-05 24.2 9.7 0.00086 19.9 0.9 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP58727.1 - 9.8e-05 22.6 7.3 0.00042 20.6 1.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP58727.1 - 0.00061 19.3 8.2 0.0077 15.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAP58727.1 - 0.0025 17.6 0.8 0.014 15.1 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP58727.1 - 0.018 15.3 7.9 0.23 11.8 1.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 OAP58727.1 - 0.042 12.9 5.7 0.41 9.6 0.5 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAP58727.1 - 0.17 12.1 3.0 8.1 6.9 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP58727.1 - 0.32 11.5 6.7 0.37 11.3 0.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP58727.1 - 1.7 8.6 4.5 9 6.3 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NAD_binding_8 PF13450.1 OAP58728.1 - 4.3e-06 26.6 0.1 2.2e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AA_permease PF00324.16 OAP58729.1 - 9.8e-134 446.2 41.4 1.1e-133 446.0 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP58729.1 - 3.2e-36 124.7 46.3 4.4e-36 124.3 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease NACHT PF05729.7 OAP58730.1 - 4e-10 39.5 0.0 1.3e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP58730.1 - 1.8e-08 34.5 1.1 1.1e-07 32.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.1 OAP58730.1 - 1.2e-06 28.3 32.6 0.061 13.2 0.1 10.4 9 2 2 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAP58730.1 - 3.1e-06 27.4 0.4 0.068 13.5 0.0 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 OAP58730.1 - 0.00018 21.6 0.0 0.00018 21.6 0.0 4.0 5 0 0 5 5 5 1 AAA domain AAA_17 PF13207.1 OAP58730.1 - 0.0053 17.5 0.0 0.035 14.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain ACT PF01842.20 OAP58730.1 - 0.017 14.5 2.4 0.33 10.4 0.0 3.4 3 0 0 3 3 3 0 ACT domain AAA_19 PF13245.1 OAP58730.1 - 0.022 14.4 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 OAP58730.1 - 0.033 14.4 0.4 0.4 10.8 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAP58730.1 - 0.06 13.6 4.8 0.11 12.8 0.3 3.4 3 1 0 3 3 3 0 AAA domain TPR_2 PF07719.12 OAP58730.1 - 1.4 8.9 7.9 18 5.5 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Kelch_3 PF13415.1 OAP58731.1 - 4.2e-24 84.0 5.6 0.001 19.1 0.0 7.0 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 OAP58731.1 - 3.9e-23 80.9 12.5 9.4e-10 38.1 0.1 7.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAP58731.1 - 8.6e-16 57.3 0.7 0.00051 20.0 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 OAP58731.1 - 1.6e-12 46.7 2.0 0.094 12.2 0.1 5.8 5 1 0 5 5 5 5 Kelch motif Kelch_2 PF07646.10 OAP58731.1 - 1.1e-10 40.7 5.9 3e-05 23.5 0.1 5.4 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 OAP58731.1 - 1.8e-09 37.3 1.6 0.1 12.5 0.0 5.5 6 0 0 6 6 6 2 Kelch motif adh_short PF00106.20 OAP58732.1 - 1.2e-23 83.8 1.0 1.9e-23 83.2 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58732.1 - 1.2e-16 61.2 0.1 1.4e-16 61.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58732.1 - 1.3e-07 31.4 0.3 2.4e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 KR domain DUF664 PF04978.7 OAP58732.1 - 0.058 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF664) MIF4G PF02854.14 OAP58733.1 - 3.6e-23 82.0 5.0 5.6e-23 81.4 3.5 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 OAP58733.1 - 1.9e-17 62.9 1.0 6.2e-17 61.3 0.0 2.5 3 0 0 3 3 3 1 MA3 domain SRP14 PF02290.10 OAP58734.1 - 5e-22 77.6 0.1 5e-22 77.6 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF3348 PF11828.3 OAP58734.1 - 0.082 12.3 1.0 0.1 12.0 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Inp1 PF12634.2 OAP58735.1 - 6.4e-28 97.2 0.2 2.2e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 ATP-synt_DE PF00401.15 OAP58736.1 - 0.0093 15.8 3.3 0.019 14.8 2.3 1.5 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Pdase_C33_assoc PF14756.1 OAP58736.1 - 0.13 12.0 0.1 0.29 10.8 0.1 1.6 1 1 1 2 2 2 0 Peptidase_C33-associated domain p450 PF00067.17 OAP58737.1 - 3.8e-66 223.4 0.0 4.7e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CECR6_TMEM121 PF14997.1 OAP58738.1 - 0.17 11.4 2.5 1.4 8.5 0.2 2.0 2 0 0 2 2 2 0 CECR6/TMEM121 family BAF1_ABF1 PF04684.8 OAP58739.1 - 0.14 10.9 1.1 0.17 10.6 0.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor adh_short PF00106.20 OAP58741.1 - 7.6e-24 84.5 0.0 9.3e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58741.1 - 2e-21 76.8 0.0 2.4e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58741.1 - 2.8e-10 40.1 0.0 4e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP58741.1 - 1.7e-06 27.6 0.0 1.9e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP58741.1 - 0.0005 20.1 0.2 0.0029 17.6 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding Bromo_MP PF01573.11 OAP58741.1 - 0.001 18.1 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Bromovirus movement protein RmlD_sub_bind PF04321.12 OAP58741.1 - 0.0013 17.7 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 OAP58741.1 - 0.0091 14.7 0.2 0.018 13.7 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAP58741.1 - 0.023 13.5 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.10 OAP58741.1 - 0.072 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus NmrA PF05368.8 OAP58741.1 - 0.14 11.4 0.0 0.49 9.5 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family ThiF PF00899.16 OAP58741.1 - 0.15 11.8 0.8 0.26 11.0 0.6 1.4 1 0 0 1 1 1 0 ThiF family EI24 PF07264.6 OAP58743.1 - 0.00017 21.0 7.9 0.0017 17.8 5.4 2.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) 3HCDH_N PF02737.13 OAP58744.1 - 4.8e-55 185.9 2.3 6.7e-55 185.5 1.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 OAP58744.1 - 7.8e-34 115.9 0.0 2.8e-33 114.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 OAP58744.1 - 2.1e-05 24.4 1.2 0.00011 22.0 0.8 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 OAP58744.1 - 0.00079 19.1 0.3 0.0013 18.4 0.2 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 OAP58744.1 - 0.0012 18.3 0.2 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 OAP58744.1 - 0.0018 17.4 0.7 0.081 12.0 0.0 2.2 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP58744.1 - 0.0029 17.8 0.1 0.0063 16.7 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 OAP58744.1 - 0.0091 15.3 0.3 0.042 13.2 0.2 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 OAP58744.1 - 0.02 14.9 0.3 0.11 12.5 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP58744.1 - 0.022 13.7 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 OAP58744.1 - 0.023 14.6 0.2 0.28 11.2 0.0 2.4 2 1 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 OAP58744.1 - 0.027 14.8 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 OAP58744.1 - 0.03 14.7 1.5 0.099 13.0 0.5 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TIMELESS PF04821.9 OAP58745.1 - 9.2e-84 280.8 0.0 2.1e-83 279.6 0.0 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 OAP58745.1 - 8.1e-26 91.0 58.1 9.3e-26 90.8 33.6 4.5 2 1 0 2 2 2 1 Timeless protein C terminal region Amidohydro_1 PF01979.15 OAP58746.1 - 7.2e-39 134.3 0.0 9.5e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 OAP58746.1 - 8.5e-06 25.2 0.5 0.0039 16.4 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP58746.1 - 0.00019 21.1 0.0 0.00042 20.0 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 OAP58746.1 - 0.018 15.0 0.0 5.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Amidohydrolase SGIII PF15467.1 OAP58746.1 - 0.034 13.2 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Secretogranin-3 cNMP_binding PF00027.24 OAP58747.1 - 4.4e-41 138.5 0.1 2e-20 72.3 0.0 4.3 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 OAP58747.1 - 1.6e-18 67.3 3.9 1.2e-17 64.5 2.7 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase ADH_N PF08240.7 OAP58748.1 - 1.3e-26 92.5 2.7 1.3e-26 92.5 1.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP58748.1 - 1.7e-24 85.8 0.0 2.5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP58748.1 - 1.4e-06 29.2 0.0 3.1e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 OAP58748.1 - 0.0013 18.3 1.7 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 OAP58748.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP58748.1 - 0.027 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 OAP58748.1 - 0.032 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF883 PF05957.8 OAP58749.1 - 0.1 12.9 0.4 0.15 12.4 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) AIG2 PF06094.7 OAP58750.1 - 1.5e-09 38.2 0.3 6.3e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 AIG2-like family RNase_H PF00075.19 OAP58751.1 - 3.5e-11 43.5 0.0 5.4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAP58751.1 - 0.00083 19.0 0.6 0.017 14.8 0.4 2.4 1 1 0 1 1 1 1 Reverse transcriptase-like Ribosomal_S2 PF00318.15 OAP58752.1 - 7.3e-51 172.3 0.0 1.6e-50 171.2 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S2 SKG6 PF08693.5 OAP58753.1 - 0.017 14.3 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 OAP58753.1 - 0.12 12.0 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SSP160 PF06933.6 OAP58754.1 - 0.16 9.9 4.8 0.2 9.6 3.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GPP34 PF05719.6 OAP58756.1 - 2.1e-65 220.6 0.3 2.7e-65 220.3 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Amidohydro_2 PF04909.9 OAP58757.1 - 3.4e-29 102.2 0.1 1.6e-17 63.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Asp PF00026.18 OAP58758.1 - 6.7e-63 212.8 3.5 8.5e-63 212.5 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAP58758.1 - 5.1e-06 26.5 0.1 5.1e-06 26.5 0.1 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAP58758.1 - 0.00011 22.5 3.7 0.059 13.8 0.2 3.9 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 OAP58758.1 - 0.00043 19.8 0.0 0.00096 18.7 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Sterol_MT_C PF08498.5 OAP58759.1 - 3.9e-27 93.9 0.1 6.2e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 OAP58759.1 - 1.2e-18 67.3 0.0 2.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP58759.1 - 3.5e-15 55.9 0.0 5.9e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP58759.1 - 1e-12 48.1 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP58759.1 - 3e-12 46.7 0.0 5.4e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAP58759.1 - 1.1e-10 41.0 0.1 1.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 OAP58759.1 - 6.7e-10 39.3 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP58759.1 - 1.9e-09 38.0 0.0 4.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP58759.1 - 6e-09 35.9 0.0 1.6e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP58759.1 - 9.9e-08 31.3 0.0 1.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 OAP58759.1 - 0.00017 20.0 0.0 0.00023 19.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 OAP58759.1 - 0.00035 19.9 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 OAP58759.1 - 0.00041 19.9 0.1 0.00061 19.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 OAP58759.1 - 0.00057 19.0 0.0 0.0012 18.0 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 OAP58759.1 - 0.0012 18.3 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 OAP58759.1 - 0.0039 16.2 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 OAP58759.1 - 0.093 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 OAP58759.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain RRM_5 PF13893.1 OAP58760.1 - 1.4e-10 40.8 0.0 3.2e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP58760.1 - 2.7e-09 36.5 0.0 5.3e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP58760.1 - 3.9e-05 23.5 0.0 7.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAP58760.1 - 0.00093 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.10 OAP58761.1 - 8.3e-05 22.3 0.1 0.00012 21.8 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAP58761.1 - 0.0015 18.6 0.1 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DnaJ PF00226.26 OAP58762.1 - 4.5e-21 74.3 2.0 4.5e-21 74.3 1.4 2.6 2 1 0 2 2 2 1 DnaJ domain PfkB PF00294.19 OAP58762.1 - 0.13 11.4 4.9 0.28 10.2 3.4 1.5 1 1 0 1 1 1 0 pfkB family carbohydrate kinase Ufd2P_core PF10408.4 OAP58762.1 - 0.67 8.1 5.4 0.81 7.8 3.2 1.5 2 0 0 2 2 2 0 Ubiquitin elongating factor core Fungal_trans PF04082.13 OAP58763.1 - 6.6e-28 97.2 0.7 1.2e-27 96.4 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Grp1_Fun34_YaaH PF01184.14 OAP58764.1 - 4.8e-84 280.8 17.8 5.8e-84 280.6 12.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ADH_zinc_N PF00107.21 OAP58765.1 - 7.4e-22 77.2 0.4 1.2e-21 76.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP58765.1 - 1.3e-05 24.9 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_2 PF03446.10 OAP58766.1 - 5.8e-39 133.5 0.7 7.9e-39 133.1 0.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP58766.1 - 2.1e-29 102.0 0.0 3.7e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MetW PF07021.7 OAP58766.1 - 0.056 12.8 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW F420_oxidored PF03807.12 OAP58766.1 - 0.067 13.6 0.1 0.25 11.7 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CoA_transf_3 PF02515.12 OAP58767.1 - 1.1e-33 116.1 0.0 4.2e-30 104.4 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Aldedh PF00171.17 OAP58768.1 - 3.6e-134 447.5 0.1 4.1e-134 447.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GTP_cyclohydro2 PF00925.15 OAP58768.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II LuxC PF05893.9 OAP58768.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ada_Zn_binding PF02805.11 OAP58769.1 - 2.7e-27 94.1 1.6 3.9e-27 93.6 1.1 1.2 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.2 OAP58769.1 - 0.043 13.9 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FlhC PF05280.6 OAP58769.1 - 0.049 13.0 0.2 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Flavin_Reduct PF01613.13 OAP58770.1 - 1.5e-12 47.6 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Pyridox_oxidase PF01243.15 OAP58770.1 - 0.0096 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.7 OAP58770.1 - 0.0097 15.4 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF447) GST_N PF02798.15 OAP58771.1 - 1.6e-11 44.2 0.0 4.1e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP58771.1 - 2.4e-10 40.2 0.1 5.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP58771.1 - 1.4e-09 38.0 0.0 3.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP58771.1 - 9.5e-08 31.9 0.0 2.9e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP58771.1 - 2.1e-06 27.5 0.1 4.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP58771.1 - 2.1e-06 28.0 0.1 5.7e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_4 PF01565.18 OAP58772.1 - 7.2e-28 96.7 0.0 1.2e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 OAP58772.1 - 1.3e-20 73.7 0.0 2.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FSH1 PF03959.8 OAP58773.1 - 1.6e-29 102.8 0.0 2.1e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 OAP58773.1 - 0.00036 20.4 0.1 0.025 14.4 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP58773.1 - 0.023 14.4 0.0 0.049 13.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP58773.1 - 0.039 13.3 0.2 0.74 9.2 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase NB-ARC PF00931.17 OAP58774.1 - 2.6e-09 36.3 0.0 3.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 OAP58774.1 - 2e-05 24.7 0.0 5.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAP58774.1 - 0.00062 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAP58774.1 - 0.00066 19.4 0.0 0.0073 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 OAP58774.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 OAP58774.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 OAP58774.1 - 0.21 10.6 0.0 0.43 9.6 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF676 PF05057.9 OAP58775.1 - 5.2e-06 25.9 0.0 8.4e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 OAP58775.1 - 3.1e-05 23.9 0.1 4.6e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP58775.1 - 0.00082 19.0 0.1 0.0014 18.2 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 OAP58775.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family ECH PF00378.15 OAP58776.1 - 2.2e-47 161.2 0.1 2.6e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF4440 PF14534.1 OAP58777.1 - 7.7e-08 32.5 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CARD PF00619.16 OAP58777.1 - 0.034 13.9 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Caspase recruitment domain CsbD PF05532.7 OAP58778.1 - 0.00027 20.5 27.9 0.0042 16.7 8.1 2.4 1 1 1 2 2 2 2 CsbD-like LEA_4 PF02987.11 OAP58778.1 - 0.19 11.6 16.1 0.55 10.1 0.1 3.0 3 1 0 3 3 3 0 Late embryogenesis abundant protein DnaJ PF00226.26 OAP58779.1 - 8.3e-12 44.6 0.4 1.6e-11 43.7 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Tannase PF07519.6 OAP58780.1 - 1.9e-93 313.7 0.4 3.7e-93 312.8 0.3 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Sugar_tr PF00083.19 OAP58781.1 - 1.6e-53 181.9 10.9 1.2e-35 122.9 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP58781.1 - 9.9e-20 70.5 26.2 3.2e-16 58.9 8.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 OAP58781.1 - 0.00063 18.5 2.5 0.00063 18.5 1.8 1.6 2 0 0 2 2 2 1 PUCC protein TRI12 PF06609.8 OAP58781.1 - 0.00084 17.6 1.2 0.00084 17.6 0.9 1.8 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 OAP58781.1 - 0.0011 17.4 2.5 0.0011 17.4 1.8 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein DUF1485 PF07364.7 OAP58782.1 - 2.5e-69 233.6 0.0 3.9e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 OAP58782.1 - 1.8e-43 148.1 0.1 3.4e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 MlrC C-terminus 2-Hacid_dh_C PF02826.14 OAP58783.1 - 7e-45 152.3 0.0 1e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP58783.1 - 0.001 18.5 0.0 0.0028 17.0 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.16 OAP58783.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 OAP58783.1 - 0.099 12.7 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aminotran_5 PF00266.14 OAP58784.1 - 2.2e-26 92.4 0.0 3.2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 OAP58784.1 - 0.015 15.1 0.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain ADH_N PF08240.7 OAP58785.1 - 3.1e-27 94.4 0.8 6.1e-27 93.5 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP58785.1 - 1.5e-15 56.9 0.1 2.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_like PF13242.1 OAP58785.1 - 0.022 14.4 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 HAD-hyrolase-like AlaDh_PNT_C PF01262.16 OAP58785.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MIT PF04212.13 OAP58786.1 - 2.3e-07 30.5 0.7 4.8e-07 29.5 0.5 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_14 PF13173.1 OAP58786.1 - 0.033 14.1 0.1 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cupin_1 PF00190.17 OAP58787.1 - 3.1e-11 42.9 0.1 4.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 OAP58787.1 - 0.00051 19.4 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AA_kinase PF00696.23 OAP58788.1 - 2.8e-27 95.8 0.7 3.9e-27 95.3 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 OAP58788.1 - 1.4e-16 59.9 0.1 4.2e-16 58.4 0.1 1.8 1 1 0 1 1 1 1 PUA domain Nucleotid_trans PF03407.11 OAP58788.1 - 0.11 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase CPSase_L_D2 PF02786.12 OAP58789.1 - 9.6e-55 185.1 0.0 1.6e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.17 OAP58789.1 - 7.3e-47 159.8 0.0 2.8e-39 134.8 0.0 2.2 2 0 0 2 2 2 2 Carboxyl transferase domain CPSase_L_chain PF00289.17 OAP58789.1 - 7e-31 106.5 0.0 2.4e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAP58789.1 - 1.3e-24 86.2 0.0 4.2e-23 81.3 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 OAP58789.1 - 1.3e-15 56.7 2.3 3.5e-15 55.3 0.6 2.4 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 OAP58789.1 - 2.2e-13 50.3 0.0 4.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 OAP58789.1 - 1.9e-09 37.0 3.3 3e-05 23.5 0.4 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATPgrasp_Ter PF15632.1 OAP58789.1 - 3.5e-08 32.5 0.0 3.2e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 OAP58789.1 - 2.9e-05 23.9 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 OAP58789.1 - 0.0003 20.0 0.0 0.4 9.7 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 OAP58789.1 - 0.00047 19.5 4.0 0.1 11.8 0.3 2.4 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 OAP58789.1 - 0.00097 19.4 0.4 0.59 10.4 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein ECH PF00378.15 OAP58789.1 - 0.0012 18.0 0.3 0.0025 16.9 0.2 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family NQRA PF05896.6 OAP58789.1 - 0.068 12.3 0.2 7.7 5.6 0.0 2.2 1 1 1 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.4 OAP58789.1 - 0.072 12.7 0.9 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_M76 PF09768.4 OAP58790.1 - 7.8e-58 194.7 6.3 1.9e-28 99.1 0.8 2.0 2 0 0 2 2 2 2 Peptidase M76 family SprT-like PF10263.4 OAP58790.1 - 0.0057 16.3 1.8 0.0088 15.7 0.7 1.8 1 1 1 2 2 2 1 SprT-like family BSP PF04450.7 OAP58790.1 - 0.032 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase of plants and bacteria KRE9 PF05390.6 OAP58791.1 - 2.5e-12 47.0 8.1 2.5e-12 47.0 5.6 1.7 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 OAP58791.1 - 3.1e-11 43.6 0.3 3.1e-11 43.6 0.2 1.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2195 PF09961.4 OAP58791.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) SRPRB PF09439.5 OAP58792.1 - 5.1e-22 77.9 0.0 2.4e-20 72.5 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 OAP58792.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 OAP58792.1 - 3.7e-05 23.0 0.0 0.0038 16.4 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.1 OAP58792.1 - 0.00021 21.3 0.1 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 OAP58792.1 - 0.00022 20.8 0.0 0.091 12.2 0.0 2.3 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 OAP58792.1 - 0.001 18.5 0.0 0.0054 16.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 OAP58792.1 - 0.0027 18.0 0.1 0.0048 17.1 0.0 1.3 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 OAP58792.1 - 0.0028 16.8 0.5 0.011 14.9 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 OAP58792.1 - 0.0053 17.2 0.2 0.05 14.1 0.1 2.3 1 1 0 1 1 1 1 Miro-like protein AAA PF00004.24 OAP58792.1 - 0.011 15.9 0.2 0.048 13.8 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.7 OAP58792.1 - 0.012 14.7 0.0 0.025 13.7 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 OAP58792.1 - 0.016 14.6 0.0 0.069 12.6 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 OAP58792.1 - 0.026 14.0 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 OAP58792.1 - 0.044 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 OAP58792.1 - 0.061 12.8 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain BatA PF07584.6 OAP58792.1 - 0.061 13.5 0.6 0.11 12.7 0.1 1.7 2 0 0 2 2 1 0 Aerotolerance regulator N-terminal Zeta_toxin PF06414.7 OAP58792.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 OAP58792.1 - 0.076 13.8 0.0 0.13 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAP58792.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Cation_efflux PF01545.16 OAP58792.1 - 0.099 11.6 0.4 0.14 11.2 0.3 1.1 1 0 0 1 1 1 0 Cation efflux family AAA_18 PF13238.1 OAP58792.1 - 0.1 12.9 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 OAP58792.1 - 0.11 11.9 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 OAP58792.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 2 0 0 2 2 1 0 AAA domain Acetyltransf_1 PF00583.19 OAP58793.1 - 1.3e-16 60.3 0.0 2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 OAP58793.1 - 4.7e-11 42.3 0.1 1.4e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 OAP58793.1 - 2.2e-10 40.5 0.0 3.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP58793.1 - 4.4e-09 36.4 0.0 8.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAP58793.1 - 2.9e-08 33.9 0.0 3.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAP58793.1 - 5.5e-06 26.3 0.0 8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 OAP58793.1 - 0.0017 17.2 0.1 0.0027 16.5 0.1 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.1 OAP58793.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP58793.1 - 0.013 15.4 0.1 0.036 13.9 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase LCAT PF02450.10 OAP58794.1 - 5.4e-95 318.6 0.1 6.5e-95 318.3 0.1 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 OAP58794.1 - 4.2e-06 26.2 0.0 8.7e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) DUF1749 PF08538.5 OAP58794.1 - 0.026 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 OAP58794.1 - 0.028 14.1 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 OAP58794.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PAP2 PF01569.16 OAP58795.1 - 6e-12 45.3 7.7 6e-12 45.3 5.4 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 OAP58795.1 - 2.2e-05 24.0 5.9 3.8e-05 23.2 4.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily FMN_dh PF01070.13 OAP58796.1 - 2.6e-117 391.6 0.0 3.4e-117 391.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 OAP58796.1 - 1.5e-09 37.2 0.7 1.8e-07 30.3 0.3 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 OAP58796.1 - 1.8e-05 24.0 0.4 3.3e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 OAP58796.1 - 2.5e-05 23.3 0.0 7.1e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.16 OAP58796.1 - 0.003 16.8 0.1 0.045 13.0 0.0 2.5 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 OAP58796.1 - 0.07 12.2 0.2 1.6 7.7 0.0 2.4 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Pex24p PF06398.6 OAP58798.1 - 9.2e-09 34.5 9.1 1.5e-08 33.8 6.3 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Apolipoprotein PF01442.13 OAP58799.1 - 0.0053 16.2 1.9 0.007 15.8 1.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 OAP58799.1 - 0.018 15.4 6.7 0.018 15.4 4.6 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HlyD_2 PF12700.2 OAP58799.1 - 0.1 11.7 8.1 0.12 11.5 5.4 1.3 1 1 0 1 1 1 0 HlyD family secretion protein Prominin PF05478.6 OAP58799.1 - 0.2 9.1 0.7 0.25 8.8 0.5 1.1 1 0 0 1 1 1 0 Prominin Jnk-SapK_ap_N PF09744.4 OAP58799.1 - 0.21 11.5 1.1 0.27 11.1 0.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ApoLp-III PF07464.6 OAP58799.1 - 0.7 9.9 12.5 7.4 6.5 2.5 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF809 PF05663.6 OAP58799.1 - 0.85 9.5 3.4 1.2 9.0 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF809) CR6_interact PF10147.4 OAP58799.1 - 1.1 8.5 8.9 1.3 8.2 6.2 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Ku_C PF03730.9 OAP58799.1 - 1.6 9.3 8.3 8.9 6.9 2.7 2.1 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm DUF4200 PF13863.1 OAP58799.1 - 1.9 8.4 12.4 4.3 7.2 8.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 OAP58799.1 - 2.2 7.1 10.2 2.7 6.8 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2317 PF10079.4 OAP58799.1 - 4.1 5.9 6.5 5 5.6 4.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Borrelia_P83 PF05262.6 OAP58799.1 - 4.9 5.3 13.4 6.1 4.9 9.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP-synt_B PF00430.13 OAP58799.1 - 6.6 6.5 20.0 3.2 7.5 9.8 2.2 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Helicase_C_2 PF13307.1 OAP58800.1 - 6.5e-54 182.3 0.1 2e-53 180.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 OAP58800.1 - 2.8e-44 150.6 0.6 4.8e-44 149.8 0.0 1.8 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 OAP58800.1 - 0.0028 17.5 1.3 1.9 8.2 0.8 3.0 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.11 OAP58800.1 - 0.012 14.9 0.0 5.4 6.1 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.24 OAP58800.1 - 0.02 14.3 0.0 4.1 6.8 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 OAP58800.1 - 0.038 14.1 0.9 7.3 6.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain Sel1 PF08238.7 OAP58801.1 - 4.9e-21 74.6 16.8 1.6e-09 38.0 0.1 6.6 6 0 0 6 6 6 5 Sel1 repeat FA_desaturase PF00487.19 OAP58802.1 - 0.6 9.4 15.7 0.29 10.5 0.6 3.0 1 1 0 2 2 2 0 Fatty acid desaturase DUF1673 PF07895.6 OAP58802.1 - 4 6.9 5.9 1.4 8.4 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Mpv17_PMP22 PF04117.7 OAP58803.1 - 3e-15 55.6 9.6 6.2e-15 54.5 6.6 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-RING_2 PF13639.1 OAP58804.1 - 1.5e-10 40.7 4.9 2.4e-10 40.0 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP58804.1 - 6.1e-08 32.5 4.0 9.4e-08 31.9 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP58804.1 - 6.6e-08 32.0 1.3 9.4e-08 31.6 0.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP58804.1 - 3.1e-07 29.9 3.4 4.7e-07 29.3 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAP58804.1 - 0.00017 21.6 5.4 0.00055 19.9 3.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 OAP58804.1 - 0.015 15.0 2.4 0.026 14.2 1.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.2 OAP58804.1 - 0.47 10.5 2.4 1.6 8.7 1.7 1.9 1 1 0 1 1 1 0 RING-variant domain ADH_zinc_N PF00107.21 OAP58805.1 - 1.1e-10 41.1 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP58805.1 - 2e-09 38.4 0.0 3.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_M16_C PF05193.16 OAP58806.1 - 2.6e-39 134.8 0.0 4.8e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 OAP58806.1 - 5.2e-39 133.3 0.3 1.6e-21 76.6 0.0 3.1 2 1 1 3 3 3 2 Insulinase (Peptidase family M16) Zn_clus PF00172.13 OAP58807.1 - 2.6e-08 33.6 8.9 4.4e-08 32.8 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP58807.1 - 0.0012 17.8 0.4 0.0028 16.5 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 OAP58808.1 - 6.9e-24 85.0 0.0 1.4e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP58808.1 - 1.9e-19 69.3 0.8 1.5e-14 53.1 0.1 3.2 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP58808.1 - 4.1e-11 42.7 0.0 1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP58808.1 - 6.8e-11 41.6 0.1 1.8e-08 33.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP58808.1 - 0.00093 19.1 0.0 0.072 12.9 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP58808.1 - 0.0047 15.8 0.0 0.043 12.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP58808.1 - 0.0098 15.0 0.0 0.032 13.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 OAP58808.1 - 0.015 15.0 5.3 0.032 14.0 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF2204 PF09970.4 OAP58808.1 - 0.024 14.1 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Pyr_redox PF00070.22 OAP58808.1 - 0.14 12.5 2.1 0.93 9.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP58808.1 - 0.19 11.7 0.1 25 4.9 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase CybS PF05328.7 OAP58809.1 - 1.9e-47 160.2 0.0 2.4e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 OAP58809.1 - 0.0005 19.8 5.3 0.024 14.4 3.7 2.2 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Maf PF02545.9 OAP58810.1 - 6.9e-53 178.6 0.2 8.6e-53 178.3 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein Rubis-subs-bind PF09273.6 OAP58810.1 - 0.026 14.4 0.1 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding AlaDh_PNT_N PF05222.10 OAP58811.1 - 1.1e-30 106.3 0.0 1.6e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 OAP58811.1 - 2.6e-13 49.8 0.0 4.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFA PF04828.9 OAP58812.1 - 0.002 18.0 0.0 0.0053 16.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HLH PF00010.21 OAP58813.1 - 7.4e-05 22.3 0.4 0.00024 20.7 0.0 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Ribonuc_L-PSP PF01042.16 OAP58816.1 - 8.2e-35 119.2 0.0 9.6e-35 118.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1682 PF07946.9 OAP58817.1 - 0.26 10.0 4.2 0.34 9.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CDC45 PF02724.9 OAP58817.1 - 1.2 7.0 7.0 1.5 6.7 4.9 1.0 1 0 0 1 1 1 0 CDC45-like protein FUSC PF04632.7 OAP58817.1 - 1.9 6.8 5.9 2.3 6.5 4.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family MFS_1 PF07690.11 OAP58819.1 - 1.3e-33 116.1 28.5 1.3e-33 116.1 19.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP58819.1 - 1.4e-10 40.3 11.3 1.4e-10 40.3 7.8 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter 2OG-FeII_Oxy PF03171.15 OAP58820.1 - 2.9e-20 72.4 0.0 4.6e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP58820.1 - 9.4e-17 61.6 0.1 1.9e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal FAD-oxidase_C PF02913.14 OAP58820.1 - 0.076 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Sugar_tr PF00083.19 OAP58821.1 - 3.2e-90 302.8 22.4 3.8e-90 302.6 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP58821.1 - 1.6e-27 96.1 23.1 1.6e-27 96.1 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.5 OAP58821.1 - 0.0045 16.7 2.6 0.014 15.1 0.2 2.2 2 0 0 2 2 2 1 Mitochondrial import protein Pam17 DUF4512 PF14975.1 OAP58822.1 - 0.19 12.5 1.7 23 5.8 0.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4512) HAD_2 PF13419.1 OAP58823.1 - 9.2e-26 91.1 0.0 4.2e-25 88.9 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP58823.1 - 0.00097 18.8 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.3 OAP58823.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) NIF PF03031.13 OAP58823.1 - 0.086 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DUF4131 PF13567.1 OAP58824.1 - 9.8 5.5 18.6 5.2 6.4 0.3 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) FAD_binding_4 PF01565.18 OAP58825.1 - 4.4e-20 71.5 2.5 4.9e-20 71.4 0.8 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAP58825.1 - 0.00013 21.7 0.2 0.00051 19.9 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like Lactamase_B PF00753.22 OAP58826.1 - 1.2e-19 70.7 1.2 1.6e-19 70.2 0.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP58826.1 - 0.039 13.5 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF951 PF06107.6 OAP58827.1 - 0.14 11.7 0.9 0.25 10.8 0.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) IF2_assoc PF08364.6 OAP58827.1 - 0.18 11.8 3.7 0.4 10.7 2.6 1.6 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region Peptidase_S10 PF00450.17 OAP58828.1 - 3.5e-129 431.6 0.1 4.3e-129 431.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 OAP58828.1 - 7.6e-09 35.7 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 OAP58828.1 - 0.0004 20.3 0.0 0.0077 16.1 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Euplotes_phero PF05842.6 OAP58828.1 - 0.016 15.5 0.5 0.036 14.4 0.4 1.6 1 1 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Ribosomal_S13 PF00416.17 OAP58829.1 - 1.8e-40 137.7 1.6 2.1e-40 137.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 OAP58829.1 - 0.024 13.2 0.0 0.025 13.1 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 OAP58829.1 - 0.051 13.5 0.6 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 HHH_6 PF14579.1 OAP58829.1 - 0.1 12.6 0.1 0.28 11.2 0.0 1.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif 2OG-FeII_Oxy PF03171.15 OAP58831.1 - 3.6e-14 52.8 0.0 5.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP58831.1 - 2.5e-13 50.5 0.0 4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Grp1_Fun34_YaaH PF01184.14 OAP58832.1 - 3.8e-26 91.7 29.3 3.7e-24 85.2 17.0 2.1 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family Patatin PF01734.17 OAP58833.1 - 3.6e-18 66.2 0.0 8.5e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 OAP58834.1 - 6.8e-09 35.9 0.2 1.9e-08 34.5 0.0 1.8 2 1 0 2 2 2 1 Patatin-like phospholipase Pyridoxal_deC PF00282.14 OAP58835.1 - 3.4e-75 252.8 0.0 4.6e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cytochrom_D1 PF02239.11 OAP58837.1 - 5.7e-07 28.1 0.0 0.16 10.1 0.0 3.4 1 1 0 3 3 3 3 Cytochrome D1 heme domain Lactonase PF10282.4 OAP58837.1 - 1.8e-05 23.9 0.0 0.1 11.6 0.0 3.2 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.1 OAP58837.1 - 4.9e-05 22.8 0.0 0.0058 16.1 0.0 2.1 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 OAP58837.1 - 0.011 15.9 1.0 19 5.6 0.0 4.1 6 0 0 6 6 6 0 PQQ-like domain DUF2724 PF10893.3 OAP58837.1 - 0.038 13.8 0.2 7.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2724) YfkB PF08756.5 OAP58837.1 - 0.048 13.2 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 YfkB-like domain DnaJ PF00226.26 OAP58838.1 - 6.8e-20 70.5 0.1 6.8e-19 67.3 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain Cauli_AT PF03233.8 OAP58838.1 - 0.073 12.7 0.5 0.13 11.9 0.4 1.5 1 0 0 1 1 1 0 Aphid transmission protein DUF1311 PF07007.7 OAP58838.1 - 0.19 11.8 2.0 0.88 9.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1311) CP2 PF04516.10 OAP58839.1 - 1e-83 280.0 0.0 1.6e-83 279.4 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor T4SS PF07996.6 OAP58839.1 - 0.058 13.2 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins DUF881 PF05949.7 OAP58839.1 - 0.061 12.7 0.8 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) Not3 PF04065.10 OAP58839.1 - 0.07 12.3 0.5 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Tektin PF03148.9 OAP58839.1 - 0.078 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Tektin family Mnd1 PF03962.10 OAP58839.1 - 0.28 10.8 3.1 0.16 11.5 0.6 1.6 2 0 0 2 2 2 0 Mnd1 family Peptidase_M24 PF00557.19 OAP58840.1 - 8.4e-37 126.7 0.0 1.2e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 MRJP PF03022.11 OAP58841.1 - 9.4e-23 80.8 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein Arylesterase PF01731.15 OAP58841.1 - 0.011 15.7 0.3 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Arylesterase Metallopep PF12044.3 OAP58842.1 - 7.9e-169 561.5 0.0 1.1e-168 561.1 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 OAP58842.1 - 0.0045 16.8 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 OAP58842.1 - 0.028 14.3 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 OAP58842.1 - 0.038 14.0 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Whi5 PF08528.6 OAP58843.1 - 5.6e-05 22.6 0.0 9.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Whi5 like PDCD2_C PF04194.8 OAP58844.1 - 8.1e-52 175.1 0.0 3.7e-50 169.7 0.0 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Glyco_trans_2_3 PF13632.1 OAP58846.1 - 1.4e-48 165.1 2.4 1.4e-48 165.1 1.7 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAP58846.1 - 1.3e-07 31.6 0.1 2.6e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 OAP58846.1 - 1.2e-05 25.1 0.0 0.00012 21.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 OAP58846.1 - 0.00068 18.0 5.7 0.001 17.4 4.0 1.2 1 0 0 1 1 1 1 Cellulose synthase Glyco_transf_21 PF13506.1 OAP58846.1 - 0.078 12.2 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 21 Ten1 PF12658.2 OAP58847.1 - 1.2e-28 99.3 0.0 1.5e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 OAP58847.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.6 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit Snf7 PF03357.16 OAP58848.1 - 1.6e-35 121.9 19.6 1.6e-35 121.9 13.6 2.0 1 1 1 2 2 2 1 Snf7 XH PF03469.9 OAP58848.1 - 0.021 14.4 5.0 0.1 12.2 2.1 2.6 2 1 0 2 2 2 0 XH domain IFT57 PF10498.4 OAP58848.1 - 0.28 9.8 14.9 0.081 11.6 8.2 1.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF3138 PF11336.3 OAP58848.1 - 1.2 7.1 12.2 1.3 7.1 7.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3138) Allexi_40kDa PF05549.6 OAP58848.1 - 1.7 7.8 7.3 2.6 7.2 4.6 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein COMPASS-Shg1 PF05205.7 OAP58848.1 - 5.4 7.3 10.1 0.9 9.8 2.5 2.3 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Viral_P18 PF04521.8 OAP58848.1 - 9.5 5.6 10.7 15 5.0 3.7 3.3 2 2 2 4 4 4 0 ssRNA positive strand viral 18kD cysteine rich protein DNA_pol_A_exo1 PF01612.15 OAP58849.1 - 2.3e-37 128.1 0.7 3.8e-37 127.4 0.5 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 OAP58849.1 - 8.1e-23 80.5 0.3 3.7e-22 78.4 0.3 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 OAP58849.1 - 7.1e-14 51.2 0.0 2e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Zn_clus PF00172.13 OAP58850.1 - 5.4e-08 32.6 10.9 1.2e-07 31.4 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 OAP58851.1 - 1.6e-22 80.0 0.0 3e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP58851.1 - 8.5e-06 25.7 0.1 1.9e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP58851.1 - 0.004 17.0 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP58851.1 - 0.0046 15.9 0.1 0.059 12.2 0.1 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 OAP58851.1 - 0.0076 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 OAP58851.1 - 0.009 14.9 0.0 0.037 12.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 OAP58851.1 - 0.011 14.5 0.0 0.062 12.1 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.9 OAP58851.1 - 0.017 13.5 0.0 0.17 10.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 OAP58851.1 - 0.074 11.6 0.0 1.8 7.0 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 OAP58851.1 - 0.085 12.6 0.0 0.53 10.0 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding FMN_red PF03358.10 OAP58852.1 - 2.5e-31 108.2 0.0 3.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 OAP58852.1 - 3.4e-07 29.9 0.0 4.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold MFS_1 PF07690.11 OAP58853.1 - 1.4e-35 122.6 24.4 1.4e-35 122.6 16.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP58853.1 - 6.5e-11 41.4 22.8 2.1e-10 39.7 15.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 OAP58853.1 - 0.00011 20.6 5.2 0.00016 20.0 3.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.16 OAP58853.1 - 0.0012 17.7 1.9 0.0012 17.7 1.3 2.3 2 0 0 2 2 2 1 POT family Fungal_trans PF04082.13 OAP58854.1 - 4.2e-24 84.8 2.1 8.1e-24 83.8 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 OAP58855.1 - 8.2e-23 81.0 0.0 1.3e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP58855.1 - 1e-07 31.2 1.3 0.0032 16.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 OAP58855.1 - 2.3e-06 26.6 0.0 4.9e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.9 OAP58855.1 - 4.9e-06 25.4 2.2 0.01 14.4 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 OAP58855.1 - 0.00012 22.0 2.7 0.00022 21.2 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP58855.1 - 0.00014 21.6 1.8 0.0076 16.0 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 OAP58855.1 - 0.0014 17.7 0.1 0.0045 16.1 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 OAP58855.1 - 0.043 12.2 0.1 0.07 11.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 OAP58855.1 - 0.049 12.4 0.2 0.089 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 OAP58855.1 - 0.058 13.4 0.2 0.31 11.0 0.1 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP58855.1 - 0.61 9.9 2.6 1.5 8.6 1.8 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amidohydro_2 PF04909.9 OAP58856.1 - 2.1e-33 116.0 0.1 2.5e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase UPF0203 PF05254.7 OAP58857.1 - 9.9e-30 102.2 1.1 1.1e-29 102.0 0.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 OAP58857.1 - 0.00017 21.5 0.6 0.00041 20.2 0.4 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 OAP58857.1 - 0.00059 19.5 2.1 0.11 12.3 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 OAP58857.1 - 0.027 14.3 0.9 4 7.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 OAP58857.1 - 0.23 11.4 1.7 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 CHCH domain COX6B PF02297.12 OAP58857.1 - 0.67 10.0 5.6 2.2 8.3 0.1 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb 2OG-FeII_Oxy_3 PF13640.1 OAP58858.1 - 4.6e-12 46.3 0.0 7.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 OAP58858.1 - 2.3e-07 30.3 0.0 4.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAP58858.1 - 0.00041 20.5 0.0 0.00068 19.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 OAP58858.1 - 0.16 10.6 0.0 0.36 9.5 0.0 1.6 1 1 0 1 1 1 0 Poxvirus C4/C10 protein Fork_head PF00250.13 OAP58859.1 - 1.6e-13 50.5 0.0 3.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 OAP58859.1 - 2.8e-06 27.3 0.1 6.9e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 FHA domain Prenylcys_lyase PF07156.9 OAP58860.1 - 4.9e-30 104.6 0.0 3e-21 75.7 0.0 2.9 3 0 0 3 3 3 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 OAP58860.1 - 2.9e-08 33.6 0.0 5.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAP58860.1 - 2e-05 23.9 0.0 0.032 13.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 OAP58860.1 - 6e-05 22.8 0.0 0.00023 20.9 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 OAP58860.1 - 0.038 12.8 0.0 0.44 9.3 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Nuc_deoxyrib_tr PF05014.10 OAP58861.1 - 6.8e-15 54.9 0.1 1.7e-14 53.6 0.0 1.6 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase DUF4406 PF14359.1 OAP58861.1 - 0.008 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4406) adh_short_C2 PF13561.1 OAP58862.1 - 4.8e-19 69.0 0.0 5.6e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP58862.1 - 5.2e-12 45.9 0.7 7.5e-12 45.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP58862.1 - 4.2e-08 33.0 0.1 6.5e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 KR domain PrsW-protease PF13367.1 OAP58862.1 - 0.024 13.8 0.1 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Protease prsW family Epimerase PF01370.16 OAP58862.1 - 0.096 12.0 0.1 6.8 6.0 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 OAP58863.1 - 0.033 12.7 0.3 0.13 10.8 0.1 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain ADH_N PF08240.7 OAP58864.1 - 1.3e-28 98.9 0.4 2.2e-28 98.1 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP58864.1 - 1.6e-22 79.4 0.2 1.6e-22 79.4 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP58864.1 - 0.00012 22.9 0.1 0.00022 22.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAP58864.1 - 0.0019 17.3 0.2 0.0036 16.4 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1967 PF09269.6 OAP58864.1 - 0.07 12.8 0.1 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Aldedh PF00171.17 OAP58865.1 - 4.7e-128 427.4 1.3 5.8e-128 427.1 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M24 PF00557.19 OAP58866.1 - 8e-51 172.5 0.1 1.1e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 OAP58866.1 - 1.6e-24 85.8 0.0 3.2e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SRF-TF PF00319.13 OAP58866.1 - 0.093 11.9 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Glyco_hydro_76 PF03663.9 OAP58867.1 - 2.4e-23 83.1 9.0 3.2e-23 82.7 6.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 adh_short PF00106.20 OAP58868.1 - 1.7e-20 73.6 0.0 2.4e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP58868.1 - 1.3e-07 31.5 0.0 2.3e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 OAP58868.1 - 3.9e-05 24.0 0.0 9.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 OAP58868.1 - 4.7e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 OAP58868.1 - 5.3e-05 23.1 0.0 6.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 OAP58868.1 - 0.00013 21.3 0.1 0.00053 19.3 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 OAP58868.1 - 0.00024 20.5 0.0 0.00051 19.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP58868.1 - 0.0006 19.8 0.0 0.00075 19.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 OAP58868.1 - 0.0087 15.2 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FTR PF01913.13 OAP58868.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase ApbA PF02558.11 OAP58868.1 - 0.046 13.1 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1776 PF08643.5 OAP58868.1 - 0.046 12.8 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pyr_redox PF00070.22 OAP58868.1 - 0.058 13.8 0.1 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.10 OAP58868.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 OAP58868.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 OAP58868.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TRI12 PF06609.8 OAP58869.1 - 1.1e-25 89.8 17.1 1.4e-25 89.5 11.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP58869.1 - 4.1e-23 81.6 43.5 4.3e-21 75.0 29.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP58869.1 - 2.7e-07 29.5 4.9 2.7e-07 29.5 3.4 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2085 PF09858.4 OAP58869.1 - 0.0075 16.3 1.2 0.036 14.1 0.8 2.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2085) DUF4538 PF15061.1 OAP58869.1 - 0.45 9.8 4.4 4.2 6.7 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Peptidase_S15 PF02129.13 OAP58870.1 - 1e-34 120.2 0.4 4e-33 114.9 0.1 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 OAP58870.1 - 4.9e-21 75.6 0.0 7.3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 OAP58870.1 - 0.00013 21.9 0.2 0.00039 20.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 OAP58871.1 - 1.4e-20 73.2 0.2 2.7e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ResB PF05140.9 OAP58871.1 - 0.1 11.1 0.4 0.17 10.4 0.3 1.3 1 0 0 1 1 1 0 ResB-like family HgmA PF04209.8 OAP58872.1 - 2e-169 563.4 0.0 2.3e-169 563.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 OAP58873.1 - 2.1e-46 158.1 0.0 3e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 OAP58873.1 - 4e-22 78.2 0.0 8.4e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal p450 PF00067.17 OAP58874.1 - 1.2e-58 198.7 0.0 1.4e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 OAP58875.1 - 1.7e-18 67.3 1.5 1.9e-18 67.1 1.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP58875.1 - 5.8e-09 35.8 0.1 8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP58875.1 - 0.0058 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 OAP58875.1 - 0.037 13.6 0.1 0.14 11.6 0.0 1.9 3 0 0 3 3 3 0 PGAP1-like protein FliG_M PF14841.1 OAP58875.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 FliG middle domain BTB PF00651.26 OAP58877.1 - 9.9e-08 31.9 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Vfa1 PF08432.5 OAP58877.1 - 0.0083 16.1 6.1 0.013 15.5 4.2 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CENP-B_dimeris PF09026.5 OAP58877.1 - 0.049 13.8 16.1 0.12 12.5 11.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 OAP58877.1 - 0.081 12.5 8.3 0.13 11.9 5.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 OAP58877.1 - 0.45 9.6 7.2 0.99 8.5 5.0 1.6 1 0 0 1 1 1 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.3 OAP58877.1 - 0.82 9.5 20.2 1.6 8.6 14.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.8 OAP58877.1 - 0.84 7.3 26.7 1.2 6.8 18.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.4 OAP58877.1 - 1.1 7.9 21.4 1.8 7.2 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.8 OAP58877.1 - 1.6 8.5 15.3 2.6 7.8 10.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 OAP58877.1 - 1.9 7.3 8.4 2.7 6.7 5.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 OAP58877.1 - 2.3 6.1 9.6 3.2 5.6 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.3 OAP58877.1 - 2.4 7.1 7.6 3.8 6.4 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.7 OAP58877.1 - 2.6 5.8 19.7 3.8 5.2 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAP58877.1 - 2.9 6.2 20.4 4.2 5.7 14.2 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 OAP58877.1 - 3.8 7.1 7.8 7.2 6.2 5.4 1.4 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.6 OAP58877.1 - 5.5 4.9 7.4 7.9 4.4 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleoplasmin PF03066.10 OAP58877.1 - 7.5 6.0 22.0 13 5.2 15.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 OAP58877.1 - 8.9 6.1 11.7 18 5.0 8.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.9 OAP58877.1 - 9 5.7 13.1 18 4.8 9.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.11 OAP58877.1 - 9.4 5.1 11.3 14 4.5 7.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mto2_bdg PF12808.2 OAP58878.1 - 3.6e-20 71.8 32.3 4.8e-18 65.0 13.6 11.5 12 1 0 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 OAP58878.1 - 4.5e-19 68.0 10.5 4.5e-19 68.0 7.3 8.3 8 1 1 10 10 10 1 Microtubule associated Reo_sigmaC PF04582.7 OAP58878.1 - 0.00015 21.0 4.0 0.00015 21.0 2.8 5.3 3 2 2 5 5 5 3 Reovirus sigma C capsid protein DUF1664 PF07889.7 OAP58878.1 - 0.31 10.8 0.0 0.31 10.8 0.0 8.4 6 2 2 9 9 9 0 Protein of unknown function (DUF1664) Sec7 PF01369.15 OAP58879.1 - 3.9e-44 150.6 0.0 8.8e-44 149.4 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 OAP58879.1 - 1.6e-17 63.7 0.0 8e-17 61.4 0.0 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain UNC-50 PF05216.8 OAP58880.1 - 7.9e-77 257.5 10.2 9.7e-77 257.2 7.1 1.0 1 0 0 1 1 1 1 UNC-50 family Glyco_hydro_44 PF12891.2 OAP58880.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase family 44 GFA PF04828.9 OAP58881.1 - 1.6e-24 85.6 0.5 2.8e-24 84.8 0.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 OAP58881.1 - 0.0007 19.2 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.6 OAP58881.1 - 0.19 11.5 2.5 2.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like NTP_transf_2 PF01909.18 OAP58882.1 - 0.0011 19.2 0.0 0.0038 17.5 0.0 2.0 1 1 0 1 1 1 1 Nucleotidyltransferase domain Glyco_transf_20 PF00982.16 OAP58883.1 - 3.2e-153 510.6 0.0 6.6e-153 509.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 OAP58883.1 - 2.3e-89 298.3 0.0 8.3e-89 296.5 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 OAP58883.1 - 0.00072 19.2 0.0 0.21 11.1 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 OAP58884.1 - 6.4e-19 67.8 52.7 6.4e-19 67.8 36.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.4 OAP58885.1 - 5.4e-31 106.4 19.0 5.4e-31 106.4 13.1 2.6 2 0 0 2 2 2 2 Casein kinase substrate phosphoprotein PP28 ANAPC15 PF15243.1 OAP58885.1 - 5.9 7.0 32.5 0.69 10.0 3.4 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 DUF1917 PF08939.5 OAP58886.1 - 2.6e-53 181.2 11.6 1.6e-39 136.0 4.2 3.3 3 1 0 3 3 3 3 Domain of unknown function (DUF1917) HeLo PF14479.1 OAP58887.1 - 1e-20 74.4 0.7 1e-20 74.4 0.5 1.7 2 0 0 2 2 2 1 Prion-inhibition and propagation PfkB PF00294.19 OAP58888.1 - 2.6e-46 158.1 2.0 5.1e-46 157.1 1.4 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 OAP58888.1 - 0.00031 20.0 0.0 0.00054 19.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Pkinase PF00069.20 OAP58889.1 - 4.4e-35 121.0 0.0 6.4e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58889.1 - 4.3e-16 58.7 0.0 6.2e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Polyketide_cyc PF03364.15 OAP58890.1 - 0.0017 18.3 0.1 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 OAP58890.1 - 0.014 15.5 0.1 0.038 14.1 0.1 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Glyco_transf_20 PF00982.16 OAP58891.1 - 1.1e-162 541.8 0.0 1.2e-162 541.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 OAP58891.1 - 0.00088 18.7 0.1 0.014 14.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 DUF1624 PF07786.7 OAP58891.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Pkinase PF00069.20 OAP58892.1 - 1.4e-20 73.5 0.0 2.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58892.1 - 6.2e-09 35.2 0.0 1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP58892.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Oxysterol_BP PF01237.13 OAP58893.1 - 8.3e-120 399.4 0.0 1.5e-119 398.6 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 OAP58893.1 - 6.7e-38 128.6 0.1 1.6e-37 127.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAP58893.1 - 2.7e-05 24.3 0.7 9.3e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 OAP58893.1 - 8.6e-05 22.7 0.2 0.00054 20.1 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Ino80_Iec3 PF14612.1 OAP58894.1 - 9.4e-60 202.5 0.6 1.3e-59 202.1 0.4 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RRM_6 PF14259.1 OAP58895.1 - 4.4e-22 77.8 0.0 1.1e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP58895.1 - 6.1e-21 73.8 0.0 4.4e-12 45.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP58895.1 - 5.7e-08 32.4 0.0 0.0077 16.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAP58895.1 - 0.0079 15.9 0.0 0.058 13.1 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Btz PF09405.5 OAP58896.1 - 6.3e-21 74.7 3.3 1.7e-20 73.3 2.3 1.8 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding ZZ PF00569.12 OAP58897.1 - 1.3e-21 75.8 54.3 8.1e-08 31.6 4.5 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type IFRD PF05004.8 OAP58898.1 - 2.1e-28 99.3 6.1 3.3e-28 98.6 4.2 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.15 OAP58898.1 - 0.0039 15.5 0.1 0.0061 14.9 0.0 1.5 1 0 0 1 1 1 1 Adaptin N terminal region PhageMin_Tail PF10145.4 OAP58898.1 - 0.027 14.1 2.1 0.07 12.7 1.5 1.7 1 0 0 1 1 1 0 Phage-related minor tail protein Corona_nucleoca PF00937.13 OAP58898.1 - 0.076 11.9 8.7 0.13 11.1 6.1 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PAP2_3 PF14378.1 OAP58899.1 - 1.6e-18 66.9 15.5 1.6e-18 66.9 10.8 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 OAP58899.1 - 0.01 16.0 1.2 0.01 16.0 0.9 3.2 4 0 0 4 4 4 0 PAP2 superfamily C-terminal PAP2 PF01569.16 OAP58899.1 - 0.17 11.5 6.8 0.52 10.0 4.6 2.0 1 1 0 1 1 1 0 PAP2 superfamily Fungal_trans_2 PF11951.3 OAP58900.1 - 0.00014 20.5 0.2 0.00034 19.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4012 PF13196.1 OAP58900.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) Prim_Zn_Ribbon PF08273.7 OAP58901.1 - 0.1 12.6 1.2 0.14 12.2 0.8 1.3 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase PhnA_Zn_Ribbon PF08274.7 OAP58901.1 - 0.13 12.1 0.2 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Gpi1 PF05024.10 OAP58902.1 - 4.3e-60 202.6 8.0 4.3e-60 202.6 5.6 1.7 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Pox_A_type_inc PF04508.7 OAP58902.1 - 0.46 10.4 2.0 4.4 7.3 0.1 3.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF155 PF02582.9 OAP58904.1 - 5.3e-41 140.4 0.0 7.7e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.15 OAP58905.1 - 7.7e-17 61.2 0.9 1.1e-14 54.2 0.2 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS WD40 PF00400.27 OAP58905.1 - 0.00078 19.2 1.7 0.038 13.8 0.4 3.5 2 1 0 2 2 2 1 WD domain, G-beta repeat zf-RING_5 PF14634.1 OAP58905.1 - 0.011 15.3 1.2 0.011 15.3 0.8 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Vps39_1 PF10366.4 OAP58905.1 - 0.18 11.8 0.3 0.53 10.3 0.2 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 OAP58905.1 - 0.3 11.2 0.0 2.5 8.2 0.0 2.3 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 OAP58905.1 - 0.41 10.5 6.9 0.7 9.7 2.9 2.2 2 0 0 2 2 2 0 Ring finger domain Tfb2 PF03849.9 OAP58906.1 - 4.9e-111 370.9 0.0 9.5e-110 366.6 0.0 2.4 2 1 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 OAP58906.1 - 9.5e-06 25.3 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Zn_clus PF00172.13 OAP58907.1 - 2.2e-07 30.6 4.8 4.1e-07 29.8 3.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP58907.1 - 0.0014 17.3 0.0 0.0022 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain 4HBT PF03061.17 OAP58908.1 - 1.9e-11 43.9 0.1 2.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 OAP58908.1 - 0.013 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Actin PF00022.14 OAP58909.1 - 1.3e-88 297.0 0.0 1.6e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 Actin PilM_2 PF11104.3 OAP58909.1 - 0.019 13.9 0.0 3.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; PrgH PF09480.5 OAP58909.1 - 0.04 12.7 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) MreB_Mbl PF06723.8 OAP58909.1 - 0.16 10.5 0.0 0.31 9.5 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein DUF2457 PF10446.4 OAP58911.1 - 0.015 14.0 2.0 0.017 13.8 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4404 PF14357.1 OAP58911.1 - 0.076 13.4 0.2 0.081 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Cupin_1 PF00190.17 OAP58912.1 - 1e-11 44.4 0.1 1.4e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 OAP58912.1 - 4.5e-06 26.0 0.0 1.4e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Cupin domain ILVD_EDD PF00920.16 OAP58913.1 - 1e-199 664.2 1.5 1.2e-199 664.1 1.1 1.0 1 0 0 1 1 1 1 Dehydratase family Ferritin_2 PF13668.1 OAP58915.1 - 4.6e-39 133.4 0.6 4.6e-39 133.4 0.4 2.1 2 1 0 2 2 2 1 Ferritin-like domain Zn_clus PF00172.13 OAP58916.1 - 4.9e-10 39.1 7.5 7.8e-10 38.5 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_28 PF03033.15 OAP58917.1 - 2.6e-25 88.7 0.0 5.4e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 OAP58917.1 - 8.5e-18 63.6 0.2 3e-15 55.4 0.0 2.7 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 OAP58917.1 - 6.2e-13 48.8 0.5 1.5e-11 44.4 0.5 2.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 OAP58917.1 - 5.1e-08 33.1 0.6 1.2e-07 32.0 0.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 OAP58917.1 - 0.00038 20.4 0.5 0.0012 18.8 0.2 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 OAP58917.1 - 0.00041 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 OAP58917.1 - 0.048 12.1 0.0 0.087 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase TPP_enzyme_N PF02776.13 OAP58918.1 - 6.4e-28 97.3 0.0 9.5e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP58918.1 - 4.8e-23 81.4 0.0 1.1e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 OAP58918.1 - 2.1e-14 53.3 0.0 5.5e-14 51.9 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 OAP58918.1 - 0.00045 19.0 0.1 0.00073 18.3 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Pkinase PF00069.20 OAP58919.1 - 1.6e-65 220.8 0.0 2.3e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP58919.1 - 3.6e-45 154.0 0.0 5.5e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP58919.1 - 1.2e-11 44.0 0.0 5.9e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 OAP58919.1 - 0.0041 16.2 0.0 0.009 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP58919.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family MBOAT_2 PF13813.1 OAP58921.1 - 1.1e-14 54.2 10.1 2.2e-14 53.2 2.8 2.6 2 1 0 2 2 2 2 Membrane bound O-acyl transferase family Ytp1 PF10355.4 OAP58922.1 - 1.3e-36 126.2 13.6 1.3e-36 126.2 9.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 OAP58922.1 - 8.8e-29 99.1 0.7 8.8e-29 99.1 0.5 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF1980 PF09323.5 OAP58922.1 - 0.026 14.2 5.5 0.055 13.2 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF1980) DUF4131 PF13567.1 OAP58922.1 - 3.4 7.0 16.5 0.19 11.1 0.1 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Lgl_C PF08596.5 OAP58924.1 - 7.6e-118 393.4 0.0 5.3e-117 390.6 0.0 2.1 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 OAP58924.1 - 4.4e-05 23.1 2.1 0.37 10.7 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat But2 PF09792.4 OAP58925.1 - 4e-07 29.9 0.6 9e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain HET PF06985.6 OAP58927.1 - 1.5e-25 89.9 1.0 7.3e-25 87.7 0.0 2.3 2 0 0 2 2 1 1 Heterokaryon incompatibility protein (HET) Mpp10 PF04006.7 OAP58927.1 - 0.0012 17.3 31.0 0.0017 16.8 21.5 1.1 1 0 0 1 1 1 1 Mpp10 protein eIF-3c_N PF05470.7 OAP58927.1 - 0.0019 16.3 9.0 0.0028 15.8 6.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.9 OAP58927.1 - 0.015 13.3 27.9 0.024 12.6 19.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAP58927.1 - 0.034 12.0 45.4 0.053 11.4 31.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 OAP58927.1 - 0.21 10.7 21.0 0.31 10.2 14.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2146 PF10220.4 OAP58927.1 - 0.38 8.6 6.4 0.57 8.0 4.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Daxx PF03344.10 OAP58927.1 - 0.6 8.5 41.7 1.1 7.6 28.9 1.3 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 OAP58927.1 - 1 8.3 2.1 1.5 7.7 1.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 OAP58927.1 - 1.1 8.5 34.3 2.3 7.5 23.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 OAP58927.1 - 2 6.0 9.5 2.8 5.5 6.6 1.1 1 0 0 1 1 1 0 Ycf1 NPR3 PF03666.8 OAP58927.1 - 3.8 5.9 7.6 5.8 5.3 5.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.2 OAP58927.1 - 5.5 4.5 6.2 7.7 4.0 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YqfQ PF14181.1 OAP58927.1 - 5.7 6.9 11.5 13 5.7 8.0 1.6 1 0 0 1 1 1 0 YqfQ-like protein CENP-T PF15511.1 OAP58927.1 - 5.9 6.0 27.2 10 5.2 18.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Astro_capsid PF03115.9 OAP58927.1 - 8.2 4.5 12.7 12 4.0 8.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SAPS PF04499.10 OAP58927.1 - 8.8 4.8 14.8 13 4.2 10.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3097 PF11296.3 OAP58928.1 - 0.071 12.1 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) RPT PF13446.1 OAP58928.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Aminotran_1_2 PF00155.16 OAP58929.1 - 4.9e-39 134.2 0.0 6.5e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAP58929.1 - 0.00097 17.5 0.0 0.0017 16.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme bcl-2I13 PF12201.3 OAP58929.1 - 0.032 13.6 0.1 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Glucan_synthase PF02364.10 OAP58930.1 - 0 1499.3 0.0 0 1498.5 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 OAP58930.1 - 7.5e-40 135.4 0.4 1.7e-39 134.3 0.3 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 OAP58931.1 - 2.2e-137 457.2 7.6 2.7e-137 456.9 5.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 OAP58931.1 - 1.7e-22 79.6 1.5 4.5e-22 78.3 1.0 1.7 1 0 0 1 1 1 1 X8 domain CFC PF09443.5 OAP58931.1 - 0.14 11.8 0.1 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Mog1 PF04603.7 OAP58932.1 - 4.3e-15 55.8 0.1 1e-11 44.9 0.0 2.6 3 0 0 3 3 3 2 Ran-interacting Mog1 protein SSP160 PF06933.6 OAP58932.1 - 1.1 7.1 11.8 0.49 8.3 6.0 1.7 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Med3 PF11593.3 OAP58932.1 - 4.5 6.4 12.6 6.2 5.9 8.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SprT-like PF10263.4 OAP58933.1 - 2.8e-46 157.0 1.1 4.9e-46 156.2 0.8 1.4 1 0 0 1 1 1 1 SprT-like family SPT6_acidic PF14632.1 OAP58933.1 - 0.0027 17.8 3.4 0.0027 17.8 2.4 2.9 2 0 0 2 2 2 1 Acidic N-terminal SPT6 Peptidase_M30 PF10460.4 OAP58933.1 - 0.088 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M30 PGBA_C PF15437.1 OAP58933.1 - 0.095 12.8 11.5 0.28 11.3 4.1 3.4 3 0 0 3 3 3 0 Plasminogen-binding protein pgbA C-terminal p450 PF00067.17 OAP58934.1 - 1.4e-53 182.0 0.0 1.8e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GvpK PF05121.7 OAP58934.1 - 0.028 14.2 0.2 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Gas vesicle protein K 2OG-FeII_Oxy_3 PF13640.1 OAP58935.1 - 0.00053 20.4 0.1 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAP58935.1 - 0.021 15.0 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ArsB PF02040.10 OAP58937.1 - 8.5e-17 61.2 13.3 1.9e-11 43.5 3.9 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein zf-H2C2_2 PF13465.1 OAP58938.1 - 4.2e-06 26.7 4.2 4.2e-06 26.7 2.9 3.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 OAP58938.1 - 7.1e-06 26.0 10.6 0.0062 16.8 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP58938.1 - 0.00026 21.0 18.4 0.0027 17.9 1.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAP58938.1 - 0.11 12.3 0.3 0.11 12.3 0.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger COG5 PF10392.4 OAP58939.1 - 4.5e-29 101.0 1.4 9.2e-29 100.0 1.0 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 PBP1_TM PF14812.1 OAP58939.1 - 0.069 13.4 2.0 0.2 11.9 1.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal COX6B PF02297.12 OAP58940.1 - 2.3e-23 82.0 3.7 3e-23 81.6 2.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SYS1 PF09801.4 OAP58941.1 - 2.8e-50 170.0 7.6 3.2e-50 169.8 5.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 OAP58941.1 - 5.8 6.6 8.0 0.52 10.0 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 NAD_binding_10 PF13460.1 OAP58942.1 - 6.9e-10 39.2 0.2 1.7e-09 37.9 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP58942.1 - 3.6e-09 36.3 0.3 4.7e-08 32.7 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP58942.1 - 1.2e-05 24.2 0.1 6.6e-05 21.7 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 OAP58942.1 - 0.00082 18.6 0.3 0.0016 17.7 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family ApbA PF02558.11 OAP58942.1 - 0.00098 18.5 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 OAP58942.1 - 0.0015 18.5 0.1 0.0027 17.7 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.12 OAP58942.1 - 0.0036 16.2 0.2 0.5 9.2 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Shikimate_DH PF01488.15 OAP58942.1 - 0.0077 16.3 0.1 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 OAP58942.1 - 0.063 12.9 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 OAP58942.1 - 0.077 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 OAP58942.1 - 0.12 11.2 0.1 0.25 10.1 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DnaJ PF00226.26 OAP58943.1 - 2.9e-23 81.3 1.8 2.9e-23 81.3 1.2 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 OAP58943.1 - 5.7e-14 51.5 6.7 8.3e-06 25.3 0.2 5.0 2 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 OAP58943.1 - 1.4e-11 43.4 5.3 0.00086 18.8 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAP58943.1 - 1.1e-10 41.2 1.9 0.007 16.1 0.1 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAP58943.1 - 2e-09 37.2 1.8 9.7 6.9 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP58943.1 - 9.3e-09 34.4 0.1 0.2 11.4 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP58943.1 - 1.8e-08 33.6 17.0 0.038 13.9 0.0 8.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP58943.1 - 2.1e-06 27.8 8.8 3.2 8.6 0.1 7.3 3 3 3 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP58943.1 - 2.4e-06 28.0 20.3 0.036 14.7 1.8 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP58943.1 - 6.6e-06 26.3 3.1 0.25 11.7 0.0 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAP58943.1 - 0.00029 20.7 6.7 9.8 6.2 0.1 5.2 3 2 2 5 5 5 1 Tetratricopeptide repeat YfiO PF13525.1 OAP58943.1 - 0.069 12.6 2.2 0.2 11.0 0.1 2.7 3 0 0 3 3 3 0 Outer membrane lipoprotein TPR_17 PF13431.1 OAP58943.1 - 0.085 13.0 2.7 1.7 9.0 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF2383 PF09537.5 OAP58943.1 - 0.11 12.7 1.3 0.5 10.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) MOZ_SAS PF01853.13 OAP58944.1 - 9.2e-47 158.7 0.5 3e-44 150.5 0.3 2.8 1 1 0 1 1 1 1 MOZ/SAS family Macoilin PF09726.4 OAP58945.1 - 0.76 7.9 8.4 1.1 7.5 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Prefoldin PF02996.12 OAP58946.1 - 3.3e-24 84.8 1.4 1.9e-21 75.9 0.0 2.5 2 1 0 2 2 2 2 Prefoldin subunit Prefoldin_2 PF01920.15 OAP58946.1 - 0.0076 15.9 1.7 0.029 14.1 0.0 2.3 2 1 1 3 3 3 1 Prefoldin subunit Sec2p PF06428.6 OAP58946.1 - 0.075 12.8 2.2 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p AAA_23 PF13476.1 OAP58947.1 - 0.11 12.7 2.2 0.19 12.0 1.5 1.4 1 0 0 1 1 1 0 AAA domain zf-MIZ PF02891.15 OAP58949.1 - 3.6e-11 42.4 0.1 7.1e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 OAP58949.1 - 0.019 14.4 0.0 0.049 13.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SAM_2 PF07647.12 OAP58950.1 - 3.6e-12 45.9 0.1 7e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 OAP58950.1 - 1.4e-10 40.3 0.0 2.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAP58950.1 - 1.8e-10 40.2 0.0 3.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 OAP58950.1 - 2.1e-08 34.2 0.0 5.9e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAP58950.1 - 4.7e-06 26.8 0.0 0.00012 22.3 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.25 OAP58950.1 - 0.001 19.1 0.3 0.0018 18.3 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 OAP58950.1 - 0.006 16.0 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Metallophos PF00149.23 OAP58951.1 - 3.3e-05 23.3 6.6 0.00019 20.9 4.6 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_fiss_reg PF05308.6 OAP58952.1 - 1.8 7.8 11.6 0.18 11.1 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator 14-3-3 PF00244.15 OAP58953.1 - 6e-117 388.8 9.4 7.1e-117 388.5 6.5 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF342 PF03961.8 OAP58953.1 - 0.061 11.7 3.1 0.075 11.4 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TPR_12 PF13424.1 OAP58953.1 - 0.072 13.0 2.8 0.065 13.1 0.5 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HisKA PF00512.20 OAP58953.1 - 0.088 12.8 0.8 10 6.2 0.0 3.0 2 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain TerB PF05099.8 OAP58953.1 - 0.15 11.8 0.2 0.15 11.8 0.1 2.4 3 0 0 3 3 3 0 Tellurite resistance protein TerB IATP PF04568.7 OAP58954.1 - 3.9e-17 62.1 8.1 1.1e-13 51.0 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial ATPase inhibitor, IATP DivIC PF04977.10 OAP58954.1 - 0.06 12.8 1.3 0.1 12.0 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF2730 PF10805.3 OAP58954.1 - 0.096 12.4 0.2 0.16 11.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) IncA PF04156.9 OAP58954.1 - 0.1 12.2 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 IncA protein COMP PF11598.3 OAP58954.1 - 4.4 7.4 5.2 22 5.1 0.3 2.4 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Nsp1_C PF05064.8 OAP58955.1 - 2.4e-33 114.2 1.6 4.3e-33 113.4 0.2 2.0 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 OAP58955.1 - 0.0041 17.3 36.7 0.0041 17.3 25.4 6.1 1 1 3 4 4 4 3 Nucleoporin FG repeat region Tropomyosin_1 PF12718.2 OAP58955.1 - 0.0065 16.3 2.3 0.013 15.2 1.6 1.4 1 0 0 1 1 1 1 Tropomyosin like HAUS-augmin3 PF14932.1 OAP58955.1 - 0.12 11.5 2.5 0.1 11.7 0.2 1.8 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4200 PF13863.1 OAP58955.1 - 4.2 7.3 5.3 2.6 8.0 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ATG16 PF08614.6 OAP58955.1 - 4.9 6.9 11.6 0.17 11.7 1.6 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fungal_trans PF04082.13 OAP58957.1 - 9.9e-09 34.4 0.1 1.6e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58957.1 - 1.7e-08 34.1 10.6 3.7e-08 33.1 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP58958.1 - 7.6e-34 116.9 61.8 1.1e-30 106.5 27.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP58958.1 - 0.028 12.9 40.4 0.058 11.9 17.9 3.0 1 1 1 2 2 2 0 Sugar (and other) transporter SAC3_GANP PF03399.11 OAP58959.1 - 1e-24 87.2 0.0 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 OAP58959.1 - 3.4e-21 75.4 0.0 1.9e-19 69.8 0.0 2.1 2 0 0 2 2 2 2 COP9 signalosome, subunit CSN8 WD40 PF00400.27 OAP58961.1 - 5.5e-33 111.6 0.0 1e-10 41.0 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 OAP58961.1 - 0.0011 18.6 0.3 0.21 11.2 0.1 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 OAP58961.1 - 0.0013 18.2 0.7 0.041 13.3 0.0 2.4 1 1 1 2 2 2 1 PQQ-like domain Gmad1 PF10647.4 OAP58961.1 - 0.0032 16.8 0.1 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 OAP58961.1 - 0.023 13.4 0.2 1.8 7.1 0.0 2.6 1 1 0 2 2 2 0 Nup133 N terminal like DUF2158 PF09926.4 OAP58961.1 - 0.12 11.8 0.0 0.58 9.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) Patatin PF01734.17 OAP58963.1 - 1.5e-21 77.2 0.1 7.2e-21 75.0 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase AAA_22 PF13401.1 OAP58963.1 - 2.2e-06 27.8 0.0 2.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP58963.1 - 3.7e-06 27.0 0.1 5.8e-05 23.1 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 OAP58963.1 - 3.8e-05 22.6 0.0 0.00011 21.2 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.1 OAP58963.1 - 0.0011 18.8 0.0 0.0097 15.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 OAP58963.1 - 0.0019 17.3 0.1 0.05 12.7 0.0 3.1 4 0 0 4 4 4 1 KaiC AAA_25 PF13481.1 OAP58963.1 - 0.0096 15.3 0.0 0.024 14.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 OAP58963.1 - 0.011 15.8 0.0 0.073 13.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAP58963.1 - 0.019 14.7 0.0 0.088 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 OAP58963.1 - 0.07 12.5 0.0 0.22 10.9 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 OAP58963.1 - 0.076 12.6 0.0 0.25 11.0 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 OAP58963.1 - 0.17 11.4 0.0 0.53 9.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 OAP58964.1 - 8.8e-39 133.2 0.0 1.1e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 OAP58965.1 - 7.6e-87 291.9 0.8 1.4e-86 291.1 0.5 1.4 1 1 0 1 1 1 1 Amidase Fungal_trans PF04082.13 OAP58966.1 - 1.8e-28 99.1 0.0 5e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP58966.1 - 1.2e-08 34.7 9.3 2.3e-08 33.8 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PCAF_N PF06466.6 OAP58966.1 - 0.066 12.5 0.0 0.2 10.9 0.0 1.7 1 1 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Aa_trans PF01490.13 OAP58967.1 - 1.6e-26 92.7 28.3 1.9e-26 92.5 19.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 OAP58967.1 - 0.078 11.4 40.8 7.7 4.9 28.3 2.3 1 1 0 1 1 1 0 Amino acid permease adh_short PF00106.20 OAP58968.1 - 7e-30 104.1 0.9 1e-29 103.6 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP58968.1 - 6.7e-25 88.2 0.0 8.4e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP58968.1 - 7.5e-11 42.0 0.6 1.8e-10 40.7 0.2 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 OAP58968.1 - 0.027 13.8 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP58968.1 - 0.047 12.5 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FTHFS PF01268.14 OAP58969.1 - 6.8e-258 856.2 0.0 9.1e-258 855.8 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 OAP58969.1 - 2.1e-67 225.2 0.9 2.1e-67 225.2 0.7 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 OAP58969.1 - 2.5e-38 130.7 0.6 5.4e-38 129.6 0.4 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 OAP58969.1 - 0.0007 19.0 0.1 0.0027 17.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC2_membrane PF01061.19 OAP58970.1 - 1.1e-75 253.3 53.7 3.8e-42 143.8 12.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 OAP58970.1 - 8.1e-33 113.6 0.0 9.3e-18 64.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 OAP58970.1 - 3.7e-32 110.0 0.2 1.7e-27 95.0 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter AAA_21 PF13304.1 OAP58970.1 - 1.5e-09 38.2 0.0 0.023 14.6 0.0 3.4 2 1 0 3 3 3 3 AAA domain ABC2_membrane_3 PF12698.2 OAP58970.1 - 1.9e-08 33.7 4.6 1.9e-08 33.7 3.2 3.6 3 2 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 OAP58970.1 - 3.2e-06 26.6 0.0 2.3e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP58970.1 - 7.9e-06 25.9 0.0 2.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 OAP58970.1 - 0.00027 20.2 0.0 1.6 7.8 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 OAP58970.1 - 0.00063 19.8 0.1 0.0053 16.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAP58970.1 - 0.0011 18.4 0.2 0.0043 16.5 0.2 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAP58970.1 - 0.0017 17.6 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 OAP58970.1 - 0.0019 17.8 0.2 0.0046 16.6 0.1 1.7 1 0 0 1 1 1 1 NACHT domain UPF0079 PF02367.12 OAP58970.1 - 0.0068 16.0 0.2 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 OAP58970.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAP58970.1 - 0.017 15.4 0.1 0.071 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 OAP58970.1 - 0.063 13.1 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAP58970.1 - 0.071 13.9 1.5 0.1 13.3 0.1 1.9 1 1 1 2 2 1 0 AAA domain AAA_28 PF13521.1 OAP58970.1 - 0.09 12.7 0.5 0.25 11.2 0.3 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 OAP58970.1 - 0.18 11.2 0.4 0.33 10.3 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 OAP58970.1 - 0.71 8.8 0.0 1.2 8.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.13 OAP58971.1 - 5.7e-26 90.9 0.1 9.6e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain EHN PF06441.7 OAP58972.1 - 1.1e-35 121.9 0.2 1.6e-35 121.4 0.1 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAP58972.1 - 2.9e-15 56.7 0.2 7.7e-15 55.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP58972.1 - 5.4e-09 35.9 0.0 1.9e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.6 OAP58972.1 - 0.0013 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) ToxN_toxin PF13958.1 OAP58973.1 - 0.13 11.9 0.8 0.29 10.8 0.6 1.5 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system CorA PF01544.13 OAP58974.1 - 5e-07 29.0 1.8 1.2e-06 27.8 0.0 2.1 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein CDP-OH_P_transf PF01066.16 OAP58975.1 - 2.2e-12 47.1 5.8 4e-12 46.3 4.0 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF981 PF06168.6 OAP58975.1 - 0.024 14.4 0.1 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF981) RPAP3_C PF13877.1 OAP58975.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Gar1 PF04410.9 OAP58976.1 - 1e-38 132.2 0.1 1.6e-38 131.5 0.1 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 OAP58977.1 - 2.5e-43 147.6 0.0 4.4e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAP58977.1 - 8.9e-17 60.8 0.2 2e-16 59.6 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 OAP58977.1 - 8.5e-12 44.7 0.0 1.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 OAP58977.1 - 3.7e-05 23.4 0.0 0.00066 19.4 0.0 2.4 2 0 0 2 2 2 1 TGS domain DUF2370 PF10176.4 OAP58978.1 - 9.2e-83 277.1 0.0 1.4e-82 276.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2477 PF10631.4 OAP58978.1 - 0.12 12.6 0.3 0.24 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Abhydrolase_5 PF12695.2 OAP58980.1 - 2.8e-07 30.3 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP58980.1 - 1.5e-06 28.2 0.6 2.2e-06 27.7 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP58980.1 - 0.053 12.7 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ceramidase PF05875.7 OAP58980.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Ceramidase PhoPQ_related PF10142.4 OAP58980.1 - 0.17 10.3 0.0 0.28 9.6 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein RRM_1 PF00076.17 OAP58981.1 - 2.3e-08 33.5 0.0 4.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP58981.1 - 5.2e-07 29.5 0.0 9.8e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP58981.1 - 0.17 11.7 0.1 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U3_assoc_6 PF08640.6 OAP58982.1 - 1.1e-28 98.7 0.3 2.4e-28 97.6 0.2 1.5 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 OAP58982.1 - 0.00013 22.3 2.0 0.14 12.8 0.2 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.5 OAP58982.1 - 0.03 13.2 0.0 0.3 9.9 0.0 2.2 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 OAP58982.1 - 0.071 12.7 0.2 0.19 11.3 0.1 1.7 1 1 0 1 1 1 0 TPR repeat Frag1 PF10277.4 OAP58983.1 - 1.5e-42 145.5 7.9 1.5e-42 145.5 5.5 3.2 3 0 0 3 3 3 2 Frag1/DRAM/Sfk1 family Methyltransf_2 PF00891.13 OAP58985.1 - 3.6e-28 98.3 0.2 9e-28 97.0 0.1 1.6 1 1 0 1 1 1 1 O-methyltransferase Rrf2 PF02082.15 OAP58985.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator Methyltransf_23 PF13489.1 OAP58985.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MarR PF01047.17 OAP58985.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 MarR family Methyltransf_18 PF12847.2 OAP58985.1 - 0.07 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 OAP58986.1 - 4.8e-68 229.7 0.0 6.1e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 OAP58987.1 - 8.4e-07 28.7 0.2 2.8e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain FAD_binding_4 PF01565.18 OAP58988.1 - 3.9e-18 65.2 1.8 9.6e-18 63.9 1.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAP58988.1 - 7e-08 32.2 0.1 1.4e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like SH2_2 PF14633.1 OAP58989.1 - 3.3e-82 274.8 0.1 3.3e-82 274.8 0.1 2.4 3 0 0 3 3 3 1 SH2 domain DLD PF14878.1 OAP58989.1 - 3.2e-36 123.9 4.9 3.2e-36 123.9 3.4 4.0 4 1 1 5 5 5 1 Death-like domain of SPT6 HHH_7 PF14635.1 OAP58989.1 - 5.7e-30 103.5 0.0 1.1e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 OAP58989.1 - 8.8e-26 90.2 0.0 3.2e-25 88.4 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 OAP58989.1 - 4.4e-19 68.6 0.9 4.4e-19 68.6 0.6 3.3 3 1 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 OAP58989.1 - 4.5e-16 58.7 34.6 4.5e-16 58.7 24.0 5.9 5 1 0 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.19 OAP58989.1 - 1.8e-05 24.4 0.0 4.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Pkinase PF00069.20 OAP58990.1 - 8.2e-59 198.8 0.0 1.8e-58 197.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain VHS PF00790.14 OAP58990.1 - 1.5e-43 147.8 0.0 3.3e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 VHS domain Pkinase_Tyr PF07714.12 OAP58990.1 - 1.4e-33 116.1 0.0 2.2e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GAT PF03127.9 OAP58990.1 - 6.8e-25 86.9 0.6 1.6e-24 85.7 0.4 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 OAP58990.1 - 1.3e-23 83.5 1.0 2.6e-23 82.5 0.7 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Kinase-like PF14531.1 OAP58990.1 - 8.2e-06 24.9 0.0 2.1e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 OAP58990.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L20 PF00453.13 OAP58991.1 - 0.16 11.8 1.4 0.27 11.1 1.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 SYCE1 PF15233.1 OAP58992.1 - 0.036 13.9 2.1 0.074 12.9 1.4 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 GAS PF13851.1 OAP58992.1 - 0.12 11.5 2.9 1.3 8.1 1.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CBS PF00571.23 OAP58993.1 - 9.5e-20 70.1 5.8 2.2e-06 27.3 0.1 5.2 5 0 0 5 5 5 4 CBS domain SGL PF08450.7 OAP58995.1 - 6.3e-22 78.1 0.2 1.2e-21 77.1 0.1 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 OAP58995.1 - 6.8e-05 22.7 0.0 0.0011 18.8 0.0 2.6 1 1 1 2 2 2 1 Arylesterase Str_synth PF03088.11 OAP58995.1 - 0.00029 20.8 0.0 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase NHL PF01436.16 OAP58995.1 - 0.49 10.4 5.0 15 5.7 0.0 3.6 3 0 0 3 3 3 0 NHL repeat Pep_deformylase PF01327.16 OAP58996.1 - 2.3e-43 147.2 0.0 3.2e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase HAD_2 PF13419.1 OAP58997.1 - 4.4e-31 108.4 0.0 5.2e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP58997.1 - 0.00061 20.2 0.0 0.00096 19.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP58997.1 - 0.00076 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like EI24 PF07264.6 OAP58998.1 - 6.3e-06 25.7 14.8 1e-05 25.0 10.1 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Sugar_tr PF00083.19 OAP58998.1 - 0.065 11.8 6.4 2 6.9 2.6 2.1 2 0 0 2 2 2 0 Sugar (and other) transporter Zn_clus PF00172.13 OAP58999.1 - 2.8e-08 33.5 9.9 4.9e-08 32.7 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP58999.1 - 0.00045 19.1 0.1 0.003 16.4 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain HNH PF01844.18 OAP59000.1 - 0.022 14.6 5.3 0.052 13.4 3.6 1.7 1 0 0 1 1 1 0 HNH endonuclease Cytochrom_c3_2 PF14537.1 OAP59000.1 - 0.1 12.9 2.3 0.22 11.8 1.6 1.5 1 0 0 1 1 1 0 Cytochrome c3 GSu_C4xC__C2xCH PF09698.5 OAP59000.1 - 1.9 8.7 5.2 2.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) zf-Sec23_Sec24 PF04810.10 OAP59001.1 - 0.04 13.4 0.7 8.9 5.9 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF3449 PF11931.3 OAP59001.1 - 0.54 9.7 4.6 9.4 5.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) zf-UBP PF02148.14 OAP59001.1 - 1.8 8.7 5.6 4.2 7.5 0.2 2.5 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein GMC_oxred_N PF00732.14 OAP59002.1 - 2.4e-76 256.7 0.0 3.1e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP59002.1 - 7.1e-35 120.4 0.0 2.3e-34 118.7 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAP59002.1 - 0.00096 18.0 0.0 0.87 8.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP59002.1 - 0.0019 17.1 0.0 0.054 12.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP59002.1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 OAP59002.1 - 0.047 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family BCAS2 PF05700.6 OAP59003.1 - 2.8e-46 157.7 0.1 3e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CHASE2 PF05226.6 OAP59003.1 - 0.027 13.7 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain IL4 PF00727.13 OAP59003.1 - 0.068 13.0 0.1 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 Interleukin 4 Ceramidase_alk PF04734.8 OAP59004.1 - 1.2e-268 892.6 0.0 1.3e-268 892.4 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Kelch_5 PF13854.1 OAP59005.1 - 3.6e-16 58.6 7.0 1.5e-07 31.1 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 OAP59005.1 - 2.4e-10 40.0 14.7 0.045 13.5 0.1 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 OAP59005.1 - 4.6e-07 29.3 9.5 0.025 14.3 0.4 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 OAP59005.1 - 8.9e-07 28.9 22.1 0.14 12.3 0.1 6.3 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAP59005.1 - 0.00069 19.6 20.7 0.48 10.6 0.3 6.0 5 1 1 6 6 6 2 Kelch motif SKG6 PF08693.5 OAP59005.1 - 0.022 14.0 2.7 0.066 12.5 1.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_1 PF01344.20 OAP59005.1 - 0.039 13.4 5.3 14 5.2 0.5 3.9 3 0 0 3 3 3 0 Kelch motif MFS_1 PF07690.11 OAP59006.1 - 1.4e-36 125.9 33.8 8.3e-35 120.1 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59006.1 - 1.7e-10 40.1 9.9 1.7e-10 40.1 6.9 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter HDV_ag PF01517.13 OAP59006.1 - 1.8 8.1 8.3 2.3 7.8 4.2 2.0 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen Ribosomal_L18e PF00828.14 OAP59008.1 - 4.3e-25 88.5 0.0 4.6e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Drc1-Sld2 PF11719.3 OAP59009.1 - 3.1e-73 247.3 10.4 6e-73 246.3 7.2 1.4 1 1 0 1 1 1 1 DNA replication and checkpoint protein Sec1 PF00995.18 OAP59010.1 - 1.8e-151 505.6 0.0 2e-151 505.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCCH PF00642.19 OAP59011.1 - 0.0037 16.8 1.0 0.0062 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Med26 PF08711.6 OAP59011.1 - 0.018 14.5 0.3 0.044 13.3 0.2 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain ArsA_ATPase PF02374.10 OAP59012.1 - 2e-114 381.7 0.1 2.3e-114 381.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 OAP59012.1 - 1.7e-17 63.5 0.3 4e-17 62.2 0.2 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAP59012.1 - 7.9e-09 35.6 0.0 3.1e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 OAP59012.1 - 1.1e-06 28.1 0.2 3e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 OAP59012.1 - 2.4e-06 27.1 0.3 0.00034 20.1 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 OAP59012.1 - 0.0009 18.6 0.1 0.0029 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAP59012.1 - 0.0051 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 OAP59012.1 - 0.011 15.4 0.0 0.037 13.7 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 OAP59012.1 - 0.027 13.6 0.1 0.073 12.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein MipZ PF09140.6 OAP59012.1 - 0.03 13.3 0.1 0.072 12.1 0.0 1.6 2 0 0 2 2 2 0 ATPase MipZ NB-ARC PF00931.17 OAP59012.1 - 0.04 12.7 0.0 0.075 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 OAP59012.1 - 0.048 12.7 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 OAP59012.1 - 0.051 13.0 0.1 0.057 12.8 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain YhjQ PF06564.7 OAP59012.1 - 0.052 12.8 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 YhjQ protein KaiC PF06745.8 OAP59012.1 - 0.058 12.4 0.1 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 KaiC MCC-bdg_PDZ PF10506.4 OAP59012.1 - 0.09 12.6 0.2 31 4.4 0.0 3.5 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FYVE_2 PF02318.11 OAP59012.1 - 0.092 12.6 1.2 0.16 11.8 0.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger MFS_1 PF07690.11 OAP59014.1 - 2.2e-42 145.0 17.2 2.2e-42 145.0 12.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59014.1 - 6.4e-15 54.6 12.6 8.9e-15 54.1 6.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAP59014.1 - 8.7e-06 24.2 0.4 1.4e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP59015.1 - 5.6e-38 130.5 3.3 1.7e-21 76.3 0.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59015.1 - 1.8e-12 46.5 4.4 2.6e-08 32.9 0.6 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter DUF791 PF05631.9 OAP59015.1 - 0.0031 16.2 1.2 0.0049 15.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 OAP59015.1 - 0.011 15.5 1.6 0.089 12.5 0.3 2.6 2 0 0 2 2 2 0 MFS_1 like family Folate_carrier PF01770.13 OAP59015.1 - 0.025 13.1 1.1 0.042 12.3 0.0 1.9 3 0 0 3 3 3 0 Reduced folate carrier OATP PF03137.15 OAP59015.1 - 0.057 11.4 2.5 0.77 7.7 0.5 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 OAP59015.1 - 0.069 11.2 11.3 0.062 11.4 1.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Zip PF02535.17 OAP59015.1 - 0.22 10.4 6.1 0.8 8.6 4.2 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter MFS_2 PF13347.1 OAP59015.1 - 0.78 8.0 22.5 0.25 9.6 9.6 2.7 2 1 0 2 2 2 0 MFS/sugar transport protein SelP_N PF04592.9 OAP59015.1 - 1.3 8.3 5.0 2.4 7.4 3.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UreE_C PF05194.7 OAP59015.1 - 2.4 8.3 12.7 0.76 9.9 5.7 2.2 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain ECH PF00378.15 OAP59016.1 - 2.3e-38 131.7 0.0 6e-38 130.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MARVEL PF01284.18 OAP59017.1 - 5.6e-28 97.5 13.9 6.8e-28 97.2 9.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain Membralin PF09746.4 OAP59017.1 - 7.4 5.4 7.9 3.8 6.4 3.8 1.7 1 1 1 2 2 2 0 Tumour-associated protein Pyr_redox_dim PF02852.17 OAP59018.1 - 6.2e-39 132.4 0.8 1.3e-38 131.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 OAP59018.1 - 7.5e-36 123.9 17.5 1.7e-34 119.4 12.1 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP59018.1 - 2.2e-22 79.2 11.5 1.1e-21 76.9 1.3 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP59018.1 - 1.8e-09 37.9 0.1 6.9e-05 22.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP59018.1 - 8.2e-09 34.7 7.0 7.3e-07 28.3 1.6 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 OAP59018.1 - 3.8e-07 29.5 6.9 5e-07 29.1 0.1 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP59018.1 - 7.2e-07 29.1 5.6 0.014 15.4 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP59018.1 - 5.3e-06 25.5 0.1 0.076 11.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 OAP59018.1 - 8e-06 24.5 14.3 0.0054 15.2 0.8 4.2 4 0 0 4 4 4 3 HI0933-like protein FAD_binding_2 PF00890.19 OAP59018.1 - 1.2e-05 24.3 11.0 6.5e-05 21.9 1.7 3.3 3 1 0 3 3 3 1 FAD binding domain DAO PF01266.19 OAP59018.1 - 3.3e-05 22.9 18.7 0.067 12.0 1.5 3.8 2 2 2 4 4 4 3 FAD dependent oxidoreductase Thi4 PF01946.12 OAP59018.1 - 0.0003 19.9 4.5 0.0051 15.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 OAP59018.1 - 0.00081 18.9 2.6 0.015 14.9 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 OAP59018.1 - 0.029 13.4 0.2 0.067 12.2 0.1 1.5 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 OAP59018.1 - 0.43 9.5 9.9 0.67 8.9 1.8 2.8 2 1 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 OAP59018.1 - 1.3 9.3 4.5 1 9.6 0.2 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 OAP59018.1 - 3.6 7.2 9.6 0.044 13.4 1.2 1.9 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 OAP59018.1 - 9.3 5.0 6.8 7.4 5.3 0.2 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein DUF572 PF04502.8 OAP59021.1 - 5.2 6.1 8.3 0.67 9.1 2.6 1.8 2 1 0 2 2 2 0 Family of unknown function (DUF572) GTP_EFTU PF00009.22 OAP59022.1 - 8e-37 126.4 3.9 5.9e-36 123.6 2.7 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 OAP59022.1 - 7.8e-22 77.2 1.0 2e-21 75.8 0.7 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 OAP59022.1 - 1.6e-12 47.3 0.5 0.00011 22.1 0.1 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAP59022.1 - 4.5e-06 26.5 0.1 1.1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP59022.1 - 0.00019 20.7 0.1 0.00039 19.7 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 OAP59022.1 - 0.00036 21.0 0.1 0.0008 19.8 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP59022.1 - 0.00044 19.5 0.0 0.00084 18.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family IF2_N PF04760.10 OAP59022.1 - 0.00068 19.2 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Ras PF00071.17 OAP59022.1 - 0.0013 18.1 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 OAP59022.1 - 0.04 13.1 0.1 0.1 11.8 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2326 PF10088.4 OAP59022.1 - 0.086 12.4 0.3 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2326) Dynamin_N PF00350.18 OAP59022.1 - 0.19 11.5 1.2 18 5.0 0.0 2.7 2 1 1 3 3 3 0 Dynamin family Mito_carr PF00153.22 OAP59023.1 - 3.1e-63 209.4 0.8 1.4e-20 72.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fer4 PF00037.22 OAP59024.1 - 1.5e-13 49.7 16.0 1.8e-08 33.6 2.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 OAP59024.1 - 2.3e-12 47.0 9.0 3.7e-12 46.4 6.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAP59024.1 - 7e-10 39.0 8.3 1.3e-09 38.1 5.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 OAP59024.1 - 1.8e-09 38.1 6.2 5.7e-05 23.7 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 OAP59024.1 - 2.4e-09 36.8 10.2 6e-09 35.5 7.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAP59024.1 - 6.8e-09 35.6 19.4 6.7e-07 29.2 6.7 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 OAP59024.1 - 8.9e-08 31.6 14.5 0.00028 20.5 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 OAP59024.1 - 1.4e-07 31.2 11.2 0.0014 18.4 1.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 OAP59024.1 - 4.1e-07 29.7 9.7 0.00029 20.9 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 OAP59024.1 - 2.3e-06 27.2 15.9 0.0023 17.6 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 OAP59024.1 - 1e-05 25.8 10.8 0.00014 22.1 7.7 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 OAP59024.1 - 5.1e-05 23.6 9.7 0.033 14.5 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 OAP59024.1 - 0.0014 18.9 15.3 0.14 12.5 2.9 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 OAP59024.1 - 0.0037 17.8 13.3 0.26 11.8 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 OAP59024.1 - 0.013 16.0 16.6 0.018 15.5 2.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 OAP59024.1 - 0.66 10.1 4.5 2.2 8.4 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 OAP59025.1 - 9.7e-11 41.7 0.3 1.4e-10 41.2 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 OAP59025.1 - 6.4e-07 29.3 0.2 1.3e-06 28.3 0.1 1.4 2 0 0 2 2 2 1 Acyl-carrier CoA_transf_3 PF02515.12 OAP59026.1 - 3.9e-52 176.2 0.1 7.3e-52 175.3 0.1 1.5 1 0 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.19 OAP59027.1 - 2.8e-36 124.8 9.9 5.7e-36 123.8 6.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAP59027.1 - 1.5e-21 77.1 0.2 1.5e-21 77.1 0.1 2.2 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAP59027.1 - 4.3e-15 54.9 0.0 9.5e-15 53.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAP59027.1 - 7.3e-15 55.4 6.5 7.3e-15 55.4 4.5 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Gly-zipper_OmpA PF13436.1 OAP59028.1 - 9.1e-06 25.3 3.9 1.8e-05 24.3 2.7 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 OAP59028.1 - 0.0024 17.5 21.1 0.0059 16.2 14.7 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain TraT PF05818.7 OAP59028.1 - 0.0068 15.8 0.5 0.009 15.4 0.3 1.4 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.1 OAP59028.1 - 0.0088 15.6 15.0 0.02 14.4 10.4 1.6 1 0 0 1 1 1 1 Glycine zipper DUF456 PF04306.8 OAP59028.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF533 PF04391.7 OAP59028.1 - 0.2 10.9 3.1 0.28 10.5 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF2076 PF09849.4 OAP59028.1 - 0.95 9.4 11.8 1.7 8.6 8.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Bacteriocin_IIc PF10439.4 OAP59028.1 - 1.3 9.1 13.0 0.88 9.7 5.5 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF3425 PF11905.3 OAP59029.1 - 2e-10 40.7 0.0 4.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) SnoaL_2 PF12680.2 OAP59030.1 - 0.034 14.5 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain ADH_zinc_N PF00107.21 OAP59031.1 - 4.2e-21 74.8 0.0 7.4e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP59031.1 - 7.1e-14 52.7 0.0 1.3e-13 51.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP59031.1 - 7.3e-10 38.5 0.0 3.2e-08 33.2 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Rep_fac-A_C PF08646.5 OAP59032.1 - 7.2e-56 187.9 7.2 1.3e-53 180.6 2.1 2.6 3 0 0 3 3 3 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 OAP59032.1 - 4.3e-19 68.1 0.3 8.9e-19 67.1 0.2 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 OAP59032.1 - 1.9e-17 62.8 0.0 4.2e-11 42.5 0.0 3.8 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain DLH PF01738.13 OAP59033.1 - 1.4e-20 73.5 0.0 2.4e-09 36.7 0.0 2.7 3 1 0 3 3 3 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP59033.1 - 1.7e-10 40.8 0.0 4.8e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP59033.1 - 0.00019 21.4 0.0 0.17 11.7 0.0 2.3 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP59033.1 - 0.11 12.0 0.4 2.7 7.5 0.3 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold EF-hand_1 PF00036.27 OAP59034.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAP59034.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAP59034.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 OAP59034.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAP59034.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 OAP59034.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 OAP59034.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 OAP59034.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 OAP59034.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 OAP59034.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 OAP59034.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 OAP59034.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 OAP59034.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 OAP59034.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 OAP59034.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 OAP59034.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 OAP59034.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 OAP59034.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 OAP59034.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 OAP59035.1 - 1.1e-17 63.4 6.3 1.7e-17 62.8 2.3 2.6 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 OAP59035.1 - 5.5e-13 48.9 1.2 5.5e-13 48.9 0.8 2.4 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 OAP59035.1 - 0.0024 17.4 8.5 0.0093 15.5 0.6 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 OAP59035.1 - 0.015 15.3 3.8 0.015 15.3 2.6 3.1 2 2 1 3 3 3 0 Syntaxin-like protein DNA_repr_REX1B PF14966.1 OAP59035.1 - 0.093 13.1 0.3 0.093 13.1 0.2 2.9 3 1 0 3 3 3 0 DNA repair REX1-B Aida_N PF08910.5 OAP59035.1 - 0.32 11.2 2.2 0.54 10.5 0.1 2.3 2 1 1 3 3 3 0 Aida N-terminus SlyX PF04102.7 OAP59035.1 - 0.93 9.9 6.8 12 6.4 0.3 3.2 2 1 1 3 3 3 0 SlyX IncA PF04156.9 OAP59035.1 - 1.1 8.7 8.3 17 4.9 1.2 3.2 3 0 0 3 3 3 0 IncA protein TMPIT PF07851.8 OAP59035.1 - 3.2 6.7 5.6 11 5.0 0.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF1090 PF06476.7 OAP59035.1 - 3.6 7.2 9.0 0.77 9.4 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) Flavodoxin_5 PF12724.2 OAP59037.1 - 0.0077 16.2 0.0 0.0088 16.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain HeLo PF14479.1 OAP59038.1 - 0.046 13.4 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 Prion-inhibition and propagation Histone PF00125.19 OAP59039.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAP59039.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 OAP59039.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 OAP59039.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAP59039.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 OAP59039.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 OAP59039.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Lectin_leg-like PF03388.8 OAP59040.1 - 1.3e-58 197.8 0.0 1.6e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 OAP59040.1 - 0.00078 18.8 0.0 0.0094 15.3 0.0 2.2 1 1 0 1 1 1 1 Legume lectin domain DUF2648 PF10855.3 OAP59040.1 - 0.19 11.1 2.7 0.51 9.8 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) zf-Tim10_DDP PF02953.10 OAP59041.1 - 3.7e-21 74.1 1.3 4.9e-21 73.7 0.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PRCC PF10253.4 OAP59041.1 - 0.031 14.9 2.0 0.035 14.8 1.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.20 OAP59042.1 - 8.7e-69 231.5 0.0 1.1e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP59042.1 - 9.6e-38 129.7 0.0 1.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP59042.1 - 2e-05 23.7 0.0 3.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAP59042.1 - 0.14 11.8 0.1 0.44 10.2 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family SIN1 PF05422.7 OAP59043.1 - 1.4e-35 122.8 0.0 2.6e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) UCH PF00443.24 OAP59044.1 - 3.9e-42 144.2 0.0 7.3e-42 143.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAP59044.1 - 2.2e-24 85.3 17.1 1.5e-19 69.8 1.1 3.2 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 OAP59044.1 - 1.7e-19 69.0 0.7 1.2e-09 37.6 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 OAP59044.1 - 7.5e-16 58.4 0.0 2e-12 47.2 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 OAP59044.1 - 0.0043 16.5 0.0 0.0091 15.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain TerY-C PF15616.1 OAP59044.1 - 0.021 14.7 5.2 1.7 8.6 0.0 2.9 2 0 0 2 2 2 0 TerY-C metal binding domain DUF2180 PF09947.4 OAP59044.1 - 1.1 9.0 8.8 31 4.4 0.3 4.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) BOP1NT PF08145.7 OAP59046.1 - 3.8e-107 357.8 7.2 5.3e-107 357.3 5.0 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 OAP59046.1 - 2.9e-27 93.5 11.0 1.3e-10 40.7 0.1 6.5 6 2 0 6 6 6 4 WD domain, G-beta repeat 4HBT PF03061.17 OAP59047.1 - 2e-13 50.2 0.1 3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 OAP59047.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Cas_Cas02710 PF09670.5 OAP59047.1 - 0.047 12.3 0.6 0.081 11.5 0.2 1.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas02710) Ank_2 PF12796.2 OAP59048.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP59048.1 - 0.06 13.6 0.0 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Tmemb_55A PF09788.4 OAP59048.1 - 0.11 11.6 0.7 0.15 11.1 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Ank PF00023.25 OAP59048.1 - 0.15 11.9 0.5 0.4 10.5 0.1 1.9 2 0 0 2 2 2 0 Ankyrin repeat zf-RING_2 PF13639.1 OAP59048.1 - 1.4 8.8 9.0 0.11 12.3 2.7 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 OAP59048.1 - 3.2 7.8 7.5 1.6 8.8 2.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PXA PF02194.10 OAP59049.1 - 8.7e-39 132.9 0.8 1.4e-38 132.2 0.0 1.8 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 OAP59049.1 - 2e-16 60.0 0.0 5e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 OAP59049.1 - 2.4e-07 30.5 0.0 7.8e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 PX domain His_biosynth PF00977.16 OAP59050.1 - 8.8e-46 156.0 0.2 4.9e-45 153.5 0.2 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 OAP59050.1 - 1.4e-27 96.4 0.0 2.2e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 OAP59050.1 - 2.3e-10 40.3 0.0 2.2e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 OAP59050.1 - 1.4e-08 34.4 0.0 5.4e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 OAP59050.1 - 0.0059 16.0 0.2 0.032 13.6 0.0 2.2 2 1 0 2 2 2 1 Peptidase C26 Acyltransferase PF01553.16 OAP59051.1 - 9.9e-33 112.3 0.0 1.6e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Rad52_Rad22 PF04098.10 OAP59052.1 - 5.8e-61 204.7 0.1 8.2e-61 204.2 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF3433 PF11915.3 OAP59053.1 - 2.1e-39 133.5 7.9 1.3e-22 79.7 0.2 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) Amino_oxidase PF01593.19 OAP59054.1 - 1.7e-43 149.3 0.1 4e-33 115.1 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP59054.1 - 4.7e-07 29.7 0.0 1.2e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP59054.1 - 0.00018 21.6 0.0 0.00043 20.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP59054.1 - 0.0094 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP59054.1 - 0.018 13.9 0.4 0.025 13.4 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 OAP59054.1 - 0.037 12.5 0.2 0.057 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 OAP59054.1 - 0.052 12.6 0.2 0.099 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 OAP59054.1 - 0.1 12.3 0.1 0.26 11.0 0.1 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding ThiF PF00899.16 OAP59054.1 - 0.15 11.8 0.1 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 ThiF family p450 PF00067.17 OAP59055.1 - 9.1e-58 195.8 0.0 1.2e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 OAP59055.1 - 3.1e-06 27.1 5.6 0.00011 22.1 0.5 3.1 1 1 1 2 2 2 2 short chain dehydrogenase DUF1762 PF08574.5 OAP59056.1 - 3.7e-12 46.4 14.5 1.2e-11 44.8 10.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1762) ATP_sub_h PF10775.4 OAP59056.1 - 0.0007 19.2 0.2 0.0045 16.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase complex subunit h NPCBM_assoc PF10633.4 OAP59056.1 - 0.037 14.0 0.2 0.094 12.7 0.1 1.7 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PUF PF00806.14 OAP59058.1 - 1.4e-30 103.0 0.0 1.9e-05 23.8 0.0 6.7 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 OAP59058.1 - 4.8e-12 45.3 0.0 1.2e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP59058.1 - 6e-08 32.5 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP59058.1 - 2.6e-07 30.3 0.0 7.8e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MxiH PF09392.5 OAP59058.1 - 0.074 13.6 2.6 0.077 13.5 0.1 2.3 2 0 0 2 2 2 0 Type III secretion needle MxiH like Myb_DNA-binding PF00249.26 OAP59059.1 - 5.4e-13 48.7 0.6 2.3e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAP59059.1 - 5.4e-12 45.6 0.1 3.8e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain MSP1_C PF07462.6 OAP59059.1 - 0.038 12.3 0.1 0.054 11.8 0.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CHDCT2 PF08074.6 OAP59059.1 - 0.11 12.2 0.2 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain FLO_LFY PF01698.11 OAP59059.1 - 0.88 8.3 5.5 1.3 7.7 3.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein PX PF00787.19 OAP59060.1 - 4.6e-25 87.6 0.1 5.5e-25 87.3 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 OAP59060.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus DNA_pol_phi PF04931.8 OAP59061.1 - 5.5e-51 173.2 30.4 2.2e-36 125.0 15.1 4.5 3 2 2 5 5 5 3 DNA polymerase phi BUD22 PF09073.5 OAP59061.1 - 1 8.3 22.4 2.1 7.3 15.5 1.5 1 0 0 1 1 1 0 BUD22 DUF2422 PF10337.4 OAP59062.1 - 1.5e-61 208.6 0.0 1.5e-61 208.6 0.0 2.1 4 0 0 4 4 4 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 OAP59062.1 - 1.2e-13 51.0 10.8 1.2e-13 51.0 7.5 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 OAP59062.1 - 9.1e-08 31.9 0.1 3.2e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) Methyltransf_23 PF13489.1 OAP59063.1 - 9.2e-26 90.4 0.0 1.3e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP59063.1 - 4.9e-11 43.2 0.0 3.1e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP59063.1 - 1.9e-10 41.1 0.0 4.6e-10 39.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP59063.1 - 9.2e-09 35.6 0.0 4.6e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP59063.1 - 9.9e-09 34.9 0.0 2.7e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP59063.1 - 3.7e-06 27.2 0.0 7.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAP59063.1 - 0.00098 19.1 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 OAP59063.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 OAP59063.1 - 0.0033 16.5 0.0 0.012 14.7 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 OAP59063.1 - 0.0045 17.0 0.0 0.022 14.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAP59063.1 - 0.0045 16.0 0.1 0.017 14.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 OAP59063.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.11 OAP59063.1 - 0.062 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CheR PF01739.13 OAP59063.1 - 0.084 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain APT PF03440.9 OAP59063.1 - 0.11 12.1 0.0 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain FAD_binding_3 PF01494.14 OAP59064.1 - 2.6e-26 92.5 0.1 4.4e-11 42.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 OAP59064.1 - 1.9e-05 23.7 0.0 0.0074 15.2 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP59064.1 - 8.9e-05 22.8 0.0 0.028 14.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP59064.1 - 0.0001 22.2 0.0 0.00026 20.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP59064.1 - 0.00016 21.5 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP59064.1 - 0.025 13.0 0.0 0.053 11.9 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 OAP59064.1 - 0.027 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 OAP59064.1 - 0.03 13.7 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 OAP59064.1 - 0.03 13.1 0.0 0.057 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain IlvN PF07991.7 OAP59064.1 - 0.032 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Amino_oxidase PF01593.19 OAP59064.1 - 0.035 13.1 0.7 1.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAP59064.1 - 0.04 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 OAP59064.1 - 0.055 12.3 0.2 0.45 9.3 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 OAP59064.1 - 0.12 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 OAP59065.1 - 2.6e-53 181.2 0.4 3.2e-53 180.8 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP59065.1 - 8.9e-06 25.9 0.4 2.9e-05 24.2 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP59065.1 - 6.7e-05 22.8 0.3 0.00016 21.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP59065.1 - 0.01 15.7 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP59065.1 - 0.017 14.2 5.0 0.14 11.1 3.5 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 OAP59065.1 - 0.025 14.0 0.4 0.049 13.0 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 OAP59065.1 - 0.028 13.4 0.2 0.063 12.3 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 OAP59065.1 - 0.028 14.1 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 OAP59065.1 - 0.032 13.3 0.1 0.075 12.1 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 OAP59065.1 - 0.053 11.9 0.3 0.077 11.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein UPF0180 PF03698.8 OAP59065.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) TrkA_N PF02254.13 OAP59065.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 OAP59065.1 - 0.09 12.5 1.1 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.1 OAP59065.1 - 0.12 12.1 0.2 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAP59065.1 - 0.16 10.8 0.7 1.3 7.8 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP59065.1 - 0.56 8.9 3.5 0.61 8.8 1.7 1.5 2 0 0 2 2 2 0 FAD binding domain adh_short PF00106.20 OAP59065.1 - 0.64 9.9 4.1 0.15 11.9 0.2 1.9 2 0 0 2 2 1 0 short chain dehydrogenase TauD PF02668.11 OAP59066.1 - 1e-47 163.0 0.7 1.4e-47 162.5 0.5 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family K_channel_TID PF07941.6 OAP59066.1 - 0.018 15.2 2.6 0.031 14.5 1.8 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain p450 PF00067.17 OAP59067.1 - 1.8e-55 188.3 0.0 2.5e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4022 PF13214.1 OAP59067.1 - 0.17 11.9 0.8 0.44 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) GTP_EFTU PF00009.22 OAP59068.1 - 3.6e-31 108.0 0.0 1.8e-30 105.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 OAP59068.1 - 1.3e-19 70.1 0.2 3.2e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 OAP59068.1 - 9.7e-12 44.8 1.4 1.8e-09 37.5 0.0 3.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAP59068.1 - 2.9e-06 27.1 0.1 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 OAP59068.1 - 0.0018 17.8 0.0 0.0045 16.5 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 OAP59068.1 - 0.043 13.9 0.0 0.29 11.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain MMS1_N PF10433.4 OAP59069.1 - 6.6e-52 176.2 0.0 1.6e-51 175.0 0.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.13 OAP59070.1 - 1.7e-24 86.4 0.0 3.1e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Yip1 PF04893.12 OAP59071.1 - 4.6e-11 42.5 14.3 7.2e-11 41.8 9.9 1.4 1 1 0 1 1 1 1 Yip1 domain CopD PF05425.8 OAP59071.1 - 0.001 19.2 8.7 0.12 12.5 1.0 2.2 2 0 0 2 2 2 2 Copper resistance protein D DUF4149 PF13664.1 OAP59071.1 - 4.6 7.3 8.4 4.7 7.3 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) V_ATPase_I PF01496.14 OAP59072.1 - 2.6e-236 786.1 0.0 3.2e-236 785.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ubiquitin PF00240.18 OAP59072.1 - 2.3e-33 113.3 0.9 5.2e-33 112.2 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 OAP59072.1 - 7.5e-30 102.2 11.0 1.4e-29 101.4 7.6 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 OAP59072.1 - 1.4e-18 66.3 0.6 4.5e-18 64.7 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAP59072.1 - 0.00017 21.7 0.4 0.00054 20.1 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAP59072.1 - 0.0042 16.7 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Telomere stability and silencing CheZ PF04344.8 OAP59072.1 - 0.022 14.4 1.3 0.066 12.8 0.0 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Baculo_PEP_C PF04513.7 OAP59072.1 - 0.081 12.7 1.2 0.34 10.7 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 OAP59072.1 - 0.12 11.7 9.4 0.71 9.2 0.1 2.5 2 1 0 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.15 OAP59072.1 - 4.2 7.1 6.0 1.2 8.8 0.5 2.7 3 0 0 3 3 3 0 Prefoldin subunit DUF3437 PF11919.3 OAP59073.1 - 1.3e-31 108.1 0.0 3.6e-31 106.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 OAP59073.1 - 3.2e-06 26.7 0.1 0.36 11.0 0.0 4.5 3 0 0 3 3 3 2 HEAT repeat CLASP_N PF12348.3 OAP59073.1 - 0.0012 18.2 0.0 0.18 11.1 0.0 3.2 3 0 0 3 3 3 1 CLASP N terminal Adaptin_N PF01602.15 OAP59073.1 - 0.3 9.3 0.0 1.6 6.9 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Isochorismatase PF00857.15 OAP59074.1 - 1.7e-20 73.6 0.0 2e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Sugar_tr PF00083.19 OAP59075.1 - 1.1e-59 202.2 27.8 3.7e-59 200.4 19.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59075.1 - 3.6e-14 52.2 30.8 6.6e-14 51.3 21.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59076.1 - 6.8e-134 446.8 28.9 7.8e-134 446.6 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59076.1 - 9.6e-25 87.0 47.2 6.5e-23 81.0 20.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 OAP59076.1 - 0.34 10.9 0.0 0.34 10.9 0.0 3.2 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Foamy_virus_ENV PF03408.9 OAP59077.1 - 0.16 9.4 1.7 0.25 8.8 1.2 1.2 1 0 0 1 1 1 0 Foamy virus envelope protein AA_permease_2 PF13520.1 OAP59078.1 - 4.9e-44 150.5 49.4 6.1e-44 150.2 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP59078.1 - 1e-25 90.0 42.1 1.3e-25 89.6 29.1 1.1 1 0 0 1 1 1 1 Amino acid permease Prefoldin_2 PF01920.15 OAP59079.1 - 0.044 13.5 1.4 1.6 8.5 0.3 2.8 3 0 0 3 3 3 0 Prefoldin subunit DUF641 PF04859.7 OAP59079.1 - 0.12 12.1 1.5 0.13 12.0 0.1 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Acyl_transf_3 PF01757.17 OAP59080.1 - 1.9e-39 135.4 24.6 2.5e-39 135.0 17.1 1.2 1 0 0 1 1 1 1 Acyltransferase family FAD-oxidase_C PF02913.14 OAP59081.1 - 1.3e-61 208.1 0.0 2e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAP59081.1 - 5.3e-34 116.6 0.0 2.6e-33 114.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain TPR_8 PF13181.1 OAP59081.1 - 0.11 12.3 0.3 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RdRP PF05183.7 OAP59082.1 - 6.4e-173 576.5 0.0 9e-173 576.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 OAP59082.1 - 0.0076 15.8 0.0 0.033 13.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP59082.1 - 0.016 15.1 0.0 0.083 12.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L21e PF01157.13 OAP59083.1 - 3e-40 136.0 6.3 3.7e-40 135.7 3.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 OAP59083.1 - 0.018 14.3 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Ribosomal_S4 PF00163.14 OAP59084.1 - 1e-29 102.7 0.9 2e-29 101.8 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 OAP59084.1 - 4.7e-13 48.3 1.0 4.7e-13 48.3 0.7 2.5 3 0 0 3 3 3 1 S4 domain ATG16 PF08614.6 OAP59085.1 - 0.00011 22.1 15.0 0.00026 20.8 2.9 2.6 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 OAP59085.1 - 0.00037 19.9 5.6 0.28 10.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Atg14 PF10186.4 OAP59085.1 - 0.00092 18.2 13.4 0.0024 16.8 0.2 2.3 1 1 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 OAP59085.1 - 0.0024 16.4 1.9 0.0032 16.0 1.3 1.2 1 0 0 1 1 1 1 AAA domain Mod_r PF07200.8 OAP59085.1 - 0.0031 17.4 12.5 0.077 12.9 1.1 3.2 2 1 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.6 OAP59085.1 - 0.0045 15.6 8.5 0.31 9.6 0.2 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein RmuC PF02646.11 OAP59085.1 - 0.0051 15.6 4.7 0.031 13.1 0.1 2.1 2 0 0 2 2 2 1 RmuC family CENP-F_leu_zip PF10473.4 OAP59085.1 - 0.034 13.9 19.4 0.022 14.6 6.0 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 L31 PF09784.4 OAP59085.1 - 0.045 13.8 3.3 0.052 13.6 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Tropomyosin_1 PF12718.2 OAP59085.1 - 0.047 13.5 11.0 0.14 12.0 2.9 2.3 2 0 0 2 2 2 0 Tropomyosin like TBPIP PF07106.8 OAP59085.1 - 0.052 13.0 7.1 0.85 9.1 1.5 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 OAP59085.1 - 0.055 13.0 12.8 0.22 11.1 0.3 2.4 1 1 1 2 2 2 0 IncA protein DUF1664 PF07889.7 OAP59085.1 - 0.057 13.2 3.7 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 OAP59085.1 - 0.074 12.4 6.2 0.21 11.0 0.2 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Lipoprotein_7 PF01540.11 OAP59085.1 - 0.082 11.9 3.6 0.2 10.6 2.5 1.6 1 1 0 1 1 1 0 Adhesin lipoprotein FlaC_arch PF05377.6 OAP59085.1 - 0.1 12.5 7.0 2.9 7.8 0.1 3.6 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF489 PF04356.7 OAP59085.1 - 0.22 11.1 2.4 1.1 8.8 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF489) CHASE3 PF05227.8 OAP59085.1 - 0.24 11.0 13.2 0.15 11.7 1.0 2.3 2 0 0 2 2 2 0 CHASE3 domain BLOC1_2 PF10046.4 OAP59085.1 - 0.39 10.8 5.6 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HALZ PF02183.13 OAP59085.1 - 0.48 10.1 0.1 0.48 10.1 0.0 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Bap31 PF05529.7 OAP59085.1 - 0.57 9.6 10.1 0.34 10.3 0.2 2.8 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like AAA_23 PF13476.1 OAP59085.1 - 0.64 10.3 3.9 16 5.7 2.7 2.1 1 1 0 1 1 1 0 AAA domain SlyX PF04102.7 OAP59085.1 - 0.73 10.2 9.0 59 4.1 3.3 3.7 3 1 0 3 3 3 0 SlyX DUF972 PF06156.8 OAP59085.1 - 0.74 10.1 9.4 12 6.3 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF2570 PF10828.3 OAP59085.1 - 1.1 8.8 5.5 0.44 10.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) TACC PF05010.9 OAP59085.1 - 1.6 8.4 9.8 12 5.6 6.6 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Cep57_CLD_2 PF14197.1 OAP59085.1 - 1.8 8.5 20.1 1.5 8.7 4.3 3.7 2 2 0 2 2 1 0 Centrosome localisation domain of PPC89 COG2 PF06148.6 OAP59085.1 - 2 8.3 10.4 5.7 6.8 0.5 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.1 OAP59085.1 - 2.1 8.3 21.1 5.8 6.8 5.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.1 OAP59085.1 - 2.8 7.0 13.6 5 6.2 2.5 2.9 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 OAP59085.1 - 3 7.3 20.0 5.5 6.5 0.0 4.3 3 1 1 4 4 4 0 Septum formation initiator V-SNARE PF05008.10 OAP59085.1 - 3.8 7.7 11.5 1.9 8.7 1.0 3.1 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus FliJ PF02050.11 OAP59085.1 - 4 7.5 14.7 4.9 7.2 0.3 2.8 1 1 1 2 2 2 0 Flagellar FliJ protein Prefoldin_2 PF01920.15 OAP59085.1 - 4.3 7.1 15.7 16 5.3 0.7 3.2 2 1 0 3 3 3 0 Prefoldin subunit HlyD PF00529.15 OAP59085.1 - 5.7 6.1 14.2 0.85 8.8 0.1 2.6 3 0 0 3 3 3 0 HlyD family secretion protein Spc24 PF08286.6 OAP59085.1 - 6.5 6.4 11.9 1.8 8.2 1.7 3.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Mnd1 PF03962.10 OAP59085.1 - 7.7 6.1 13.8 0.78 9.3 0.4 2.3 1 1 0 2 2 2 0 Mnd1 family MscS_porin PF12795.2 OAP59085.1 - 7.8 5.7 15.6 0.017 14.4 3.1 2.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Zip PF02535.17 OAP59086.1 - 0.025 13.5 6.0 0.026 13.5 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mito_carr PF00153.22 OAP59087.1 - 7.6e-76 249.9 1.4 5.1e-25 87.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CRF PF00473.12 OAP59087.1 - 0.61 10.2 1.9 18 5.5 0.1 2.9 3 0 0 3 3 3 0 Corticotropin-releasing factor family CN_hydrolase PF00795.17 OAP59088.1 - 1.8e-28 99.1 0.0 2.7e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acyl-CoA_dh_1 PF00441.19 OAP59089.1 - 1.4e-28 99.8 0.6 2.2e-28 99.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP59089.1 - 1.1e-15 56.7 0.0 2.3e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAP59089.1 - 1.5e-15 57.7 0.2 4.5e-15 56.2 0.0 1.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAP59089.1 - 5.1e-13 49.4 1.1 8.4e-13 48.7 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain bZIP_1 PF00170.16 OAP59090.1 - 0.013 15.4 4.7 0.017 15.1 2.7 1.5 1 1 0 1 1 1 0 bZIP transcription factor SBF PF01758.11 OAP59091.1 - 4.4e-50 169.6 8.7 4.4e-50 169.6 6.0 2.2 2 2 0 2 2 2 1 Sodium Bile acid symporter family DUF1793 PF08760.6 OAP59092.1 - 1e-71 240.2 0.7 2.1e-71 239.2 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Pyr_redox_3 PF13738.1 OAP59093.1 - 0.00024 21.2 0.0 0.00043 20.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Acid_PPase PF12689.2 OAP59094.1 - 9e-56 188.1 0.0 1.3e-55 187.5 0.0 1.2 1 1 0 1 1 1 1 Acid Phosphatase Ank_2 PF12796.2 OAP59095.1 - 7.2e-48 160.8 3.6 7.4e-19 67.8 0.1 6.6 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP59095.1 - 1e-37 127.7 4.2 1.5e-09 38.1 0.0 8.3 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP59095.1 - 8e-36 121.2 13.1 1.4e-08 34.6 0.0 7.7 6 2 2 8 8 7 6 Ankyrin repeats (many copies) Ank PF00023.25 OAP59095.1 - 5e-34 114.4 13.7 7e-08 31.9 0.0 12.5 13 0 0 13 13 13 6 Ankyrin repeat Ank_3 PF13606.1 OAP59095.1 - 4.9e-28 94.3 8.3 4.5e-05 23.2 0.0 11.5 12 0 0 12 12 12 5 Ankyrin repeat SPRY PF00622.23 OAP59095.1 - 3.2e-15 56.3 0.0 6.3e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 SPRY domain NACHT PF05729.7 OAP59095.1 - 3.8e-09 36.4 0.0 9.6e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 OAP59095.1 - 1.2e-06 27.7 0.3 0.0026 16.7 0.0 2.4 1 1 1 2 2 2 2 KAP family P-loop domain AAA_16 PF13191.1 OAP59095.1 - 1.8e-05 24.7 0.0 7e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 OAP59095.1 - 0.00074 18.4 0.1 0.00074 18.4 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 OAP59095.1 - 0.0047 16.6 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 OAP59095.1 - 0.02 15.2 2.4 0.38 11.0 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 OAP59095.1 - 0.09 12.6 1.4 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 OAP59095.1 - 0.13 12.3 1.4 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain YebO PF13974.1 OAP59095.1 - 2.3 8.0 11.1 0.13 12.0 2.7 2.6 3 0 0 3 3 2 0 YebO-like protein Herpes_gE PF02480.11 OAP59097.1 - 0.00019 19.8 0.1 0.00029 19.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 OAP59097.1 - 0.00077 18.7 1.4 0.0016 17.6 1.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Shisa PF13908.1 OAP59097.1 - 0.0076 16.4 0.6 0.014 15.6 0.1 1.7 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Epiglycanin_C PF14654.1 OAP59097.1 - 0.016 15.2 0.1 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region GPI-anchored PF10342.4 OAP59097.1 - 0.036 14.5 0.3 0.066 13.6 0.2 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family IncA PF04156.9 OAP59097.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF1180 PF06679.7 OAP59097.1 - 0.22 11.4 2.9 1.8 8.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) AMP-binding PF00501.23 OAP59098.1 - 8.6e-52 175.9 0.0 1.2e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP59098.1 - 0.012 16.4 0.0 0.025 15.5 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain HET PF06985.6 OAP59099.1 - 6.9e-23 81.3 0.9 1.1e-22 80.6 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lyase_1 PF00206.15 OAP59100.1 - 3.5e-90 302.3 0.0 5.7e-90 301.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 OAP59100.1 - 2.1e-26 91.7 0.2 4.8e-26 90.6 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1216 PF06746.6 OAP59100.1 - 0.026 14.2 0.1 0.068 12.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) SAPS PF04499.10 OAP59101.1 - 5.9e-198 658.3 0.0 1.4e-197 657.1 0.0 1.6 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Snf7 PF03357.16 OAP59102.1 - 3.5e-45 153.4 16.1 4.1e-45 153.2 11.2 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 OAP59102.1 - 0.011 15.2 10.7 0.032 13.6 6.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 OAP59102.1 - 0.017 15.3 10.1 0.36 11.1 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1395 PF07160.7 OAP59102.1 - 0.055 12.9 8.7 0.054 12.9 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) HHH_2 PF12826.2 OAP59102.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Reo_sigmaC PF04582.7 OAP59102.1 - 0.082 12.0 4.2 0.23 10.6 0.5 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 OAP59102.1 - 0.12 12.2 10.7 1.4 8.7 5.4 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliD_C PF07195.7 OAP59102.1 - 0.14 11.4 0.2 0.14 11.4 0.2 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2205 PF10224.4 OAP59102.1 - 0.18 11.4 4.6 2.1 8.0 1.2 2.9 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) FlaC_arch PF05377.6 OAP59102.1 - 0.39 10.6 8.4 0.5 10.2 0.1 3.1 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 OAP59102.1 - 0.46 8.8 12.4 0.18 10.2 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) OmpH PF03938.9 OAP59102.1 - 0.5 10.2 18.5 0.032 14.1 6.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Mod_r PF07200.8 OAP59102.1 - 0.96 9.3 10.1 0.43 10.4 3.3 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.4 OAP59102.1 - 0.96 8.3 9.9 1.4 7.8 6.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Allexi_40kDa PF05549.6 OAP59102.1 - 1 8.5 4.1 4.1 6.6 0.1 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4140 PF13600.1 OAP59102.1 - 1.7 9.1 0.0 1.7 9.1 0.0 3.0 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.2 OAP59102.1 - 1.8 8.4 10.8 0.51 10.1 0.9 2.3 1 1 1 2 2 2 0 Tropomyosin like AAA_13 PF13166.1 OAP59102.1 - 1.9 6.8 10.6 8.6 4.6 7.6 1.7 1 1 0 1 1 1 0 AAA domain DUF4337 PF14235.1 OAP59102.1 - 3.6 7.3 8.3 0.69 9.7 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) COG2 PF06148.6 OAP59102.1 - 6.1 6.7 8.4 7.1 6.5 1.0 2.8 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.5 OAP59102.1 - 6.3 6.9 13.6 47 4.0 6.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sld5 PF05916.6 OAP59103.1 - 1.4e-12 47.8 0.0 1.8e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Solute_trans_a PF03619.11 OAP59104.1 - 4.7e-51 173.7 10.6 5.4e-51 173.5 7.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF165 PF02592.10 OAP59104.1 - 3.8 7.6 10.5 0.67 10.1 4.1 1.9 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 Hexapep PF00132.19 OAP59105.1 - 4.3e-13 48.1 9.1 2.4e-07 29.9 1.8 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAP59105.1 - 0.00036 20.0 7.2 0.63 9.6 0.4 4.0 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase HET PF06985.6 OAP59106.1 - 4.8e-22 78.6 0.0 8.9e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1910 PF08928.5 OAP59106.1 - 0.19 11.7 0.0 0.49 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Myb_DNA-binding PF00249.26 OAP59108.1 - 0.0025 17.8 0.1 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain LMBR1 PF04791.11 OAP59110.1 - 1.9e-28 99.2 5.6 2.4e-28 98.9 3.9 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Filament PF00038.16 OAP59110.1 - 0.19 11.1 0.2 7.9 5.8 0.0 2.0 2 0 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 OAP59110.1 - 0.2 11.2 0.0 0.2 11.2 0.0 2.9 3 0 0 3 3 3 0 IncA protein MgtE PF01769.11 OAP59110.1 - 6.4 7.0 9.3 1.4 9.1 0.1 3.2 3 0 0 3 3 3 0 Divalent cation transporter SUR7 PF06687.7 OAP59111.1 - 4e-25 88.6 13.7 5e-25 88.3 9.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family CobD_Cbib PF03186.8 OAP59111.1 - 0.04 13.0 1.8 0.061 12.3 1.3 1.2 1 0 0 1 1 1 0 CobD/Cbib protein NfeD PF01957.13 OAP59111.1 - 1.3 9.1 4.3 0.18 11.9 0.2 1.6 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Fungal_trans_2 PF11951.3 OAP59112.1 - 2e-08 33.2 0.1 8.4e-08 31.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ion_trans_2 PF07885.11 OAP59113.1 - 9.7e-26 89.2 23.1 5.9e-16 57.9 3.5 3.4 4 0 0 4 4 4 2 Ion channel GWT1 PF06423.7 OAP59113.1 - 1.3 9.1 6.1 0.57 10.2 0.5 2.6 2 1 0 3 3 3 0 GWT1 Pyr_redox_3 PF13738.1 OAP59114.1 - 9.8e-15 55.1 0.0 5.4e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP59114.1 - 1.4e-08 33.4 0.1 3.1e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP59114.1 - 1.6e-07 31.3 0.0 0.003 17.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP59114.1 - 2e-07 30.9 0.0 8.8e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP59114.1 - 3.7e-05 22.8 0.0 0.0057 15.6 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAP59114.1 - 0.0014 17.6 0.0 1.4 7.7 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP59114.1 - 0.0058 15.5 0.0 0.021 13.7 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAP59114.1 - 0.027 14.2 0.3 0.2 11.4 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 OAP59114.1 - 0.029 13.4 0.2 0.23 10.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Methyltransf_23 PF13489.1 OAP59115.1 - 2.2e-19 69.7 0.0 3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP59115.1 - 9.7e-09 35.6 0.0 4.2e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP59115.1 - 2.5e-08 33.6 0.0 1.9e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP59115.1 - 4.9e-08 33.5 0.0 2.3e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP59115.1 - 5.9e-07 29.8 0.0 1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP59115.1 - 6.5e-07 29.6 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAP59115.1 - 6.8e-05 21.9 0.5 0.00011 21.2 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 OAP59115.1 - 0.0055 16.7 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 OAP59115.1 - 0.0058 16.0 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAP59115.1 - 0.022 14.7 0.0 0.038 14.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.14 OAP59116.1 - 1.1e-25 90.4 0.2 4.9e-12 45.5 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 OAP59116.1 - 7.8e-07 28.3 0.1 0.0018 17.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP59116.1 - 0.00024 21.4 0.0 0.038 14.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP59116.1 - 0.00078 19.4 0.2 0.0025 17.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP59116.1 - 0.0027 16.6 0.0 0.012 14.5 0.0 2.0 2 1 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 OAP59116.1 - 0.011 14.1 0.3 0.029 12.8 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 OAP59116.1 - 0.012 14.7 0.2 0.019 14.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 OAP59116.1 - 0.013 14.6 0.1 0.1 11.6 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 OAP59116.1 - 0.032 14.1 0.2 0.055 13.3 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 OAP59116.1 - 0.041 13.3 0.0 0.096 12.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 OAP59116.1 - 0.047 13.4 0.1 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 OAP59116.1 - 0.14 12.2 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 OAP59116.1 - 0.15 11.7 0.6 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B PF00753.22 OAP59117.1 - 2.1e-10 40.5 0.6 2.7e-10 40.2 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP59117.1 - 0.0011 18.5 0.1 0.0018 17.8 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NMO PF03060.10 OAP59118.1 - 1.1e-37 129.8 7.1 1.3e-36 126.4 4.9 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAP59118.1 - 0.00024 20.1 0.8 0.012 14.4 0.5 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAP59118.1 - 0.011 14.6 3.4 0.015 14.2 2.3 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Methyltrn_RNA_3 PF02598.12 OAP59119.1 - 1.3e-84 284.0 0.0 1.5e-84 283.7 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 OAP59119.1 - 0.16 11.8 0.0 9.4 6.1 0.0 2.2 2 0 0 2 2 2 0 SpoU rRNA Methylase family BLVR PF06375.6 OAP59119.1 - 0.85 9.4 3.5 1.5 8.6 2.4 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) UPF0016 PF01169.14 OAP59120.1 - 7e-41 138.2 24.8 9.9e-21 73.6 5.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Kelch_5 PF13854.1 OAP59122.1 - 1.8e-13 50.1 18.9 4.4e-11 42.4 0.3 5.3 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 OAP59122.1 - 6.6e-09 35.3 16.9 0.00088 18.9 0.1 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAP59122.1 - 8.3e-09 35.2 8.4 0.16 12.2 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 OAP59122.1 - 2.4e-06 27.5 17.3 0.0023 18.0 0.2 6.2 5 1 0 5 5 5 3 Galactose oxidase, central domain VSP PF03302.8 OAP59122.1 - 0.0014 17.3 0.3 0.0023 16.6 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Kelch_2 PF07646.10 OAP59122.1 - 0.049 13.4 4.8 22 5.0 0.0 4.2 3 1 0 3 3 3 0 Kelch motif Herpes_gE PF02480.11 OAP59122.1 - 0.17 10.1 0.1 0.23 9.6 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_1 PF01344.20 OAP59122.1 - 4.2 7.0 14.1 0.68 9.5 0.4 5.2 6 0 0 6 6 6 0 Kelch motif Aa_trans PF01490.13 OAP59123.1 - 4.5e-41 140.6 33.2 5.4e-41 140.4 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 OAP59123.1 - 6.5e-07 28.2 34.4 6.5e-07 28.2 23.8 2.1 1 1 1 2 2 2 1 Amino acid permease CAAD PF14159.1 OAP59123.1 - 0.078 12.6 5.9 0.16 11.6 0.5 2.9 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF4134 PF13572.1 OAP59123.1 - 0.92 9.6 6.4 1.6 8.8 1.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) TPR_11 PF13414.1 OAP59124.1 - 5.6e-42 141.2 13.0 2.1e-15 56.1 0.9 5.5 3 2 3 6 6 6 5 TPR repeat TPR_2 PF07719.12 OAP59124.1 - 4.6e-32 107.3 10.8 2.6e-06 26.9 0.3 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 OAP59124.1 - 1.1e-31 107.0 13.5 3.6e-08 32.6 0.4 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 OAP59124.1 - 6.7e-23 80.8 24.5 1.1e-05 25.6 0.2 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat DnaJ PF00226.26 OAP59124.1 - 4e-20 71.3 8.1 1.2e-19 69.8 2.3 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.1 OAP59124.1 - 2.1e-19 68.2 13.2 0.0064 17.0 0.5 7.8 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 OAP59124.1 - 6.6e-19 68.0 20.2 8.7e-05 23.0 0.2 6.9 5 3 2 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 OAP59124.1 - 1.2e-17 62.5 10.7 0.013 15.6 0.2 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 OAP59124.1 - 1.5e-13 49.4 13.9 0.018 14.7 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAP59124.1 - 2.2e-13 48.9 9.1 0.056 13.2 0.1 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAP59124.1 - 2.4e-13 49.8 10.3 0.014 15.3 0.3 5.6 3 2 1 4 4 4 4 Tetratricopeptide repeat Apc3 PF12895.2 OAP59124.1 - 8.2e-13 48.3 4.1 1.1e-05 25.4 0.1 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 OAP59124.1 - 5.7e-10 38.9 5.1 0.00019 21.2 0.0 5.0 4 2 2 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 OAP59124.1 - 2.2e-07 30.8 16.8 0.92 10.1 0.1 8.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAP59124.1 - 9.9e-07 28.5 7.8 7.7e-05 22.4 0.1 4.2 3 2 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 OAP59124.1 - 3.9e-06 27.2 3.2 0.06 13.6 0.0 4.1 2 2 3 5 5 5 2 Bacterial transcriptional activator domain TOM20_plant PF06552.7 OAP59124.1 - 6.9e-06 25.7 3.5 0.059 12.9 0.1 3.8 2 2 1 4 4 4 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.1 OAP59124.1 - 7.6e-05 22.5 8.2 6.7 6.7 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.5 OAP59124.1 - 0.014 14.2 0.6 0.28 9.9 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) RPT PF13446.1 OAP59124.1 - 0.022 14.1 3.4 0.16 11.4 0.0 3.5 3 0 0 3 3 3 0 A repeated domain in UCH-protein Coatomer_E PF04733.9 OAP59124.1 - 0.075 12.2 3.9 0.49 9.5 0.3 2.7 2 1 1 3 3 3 0 Coatomer epsilon subunit MIT PF04212.13 OAP59124.1 - 0.31 10.9 7.8 7 6.6 0.1 5.0 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 OAP59124.1 - 0.37 10.0 6.8 14 5.0 0.0 4.8 6 0 0 6 6 6 0 SHNi-TPR MAGE PF01454.14 OAP59125.1 - 4.4e-38 130.5 0.0 6.2e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 MAGE family DUF1770 PF08589.5 OAP59125.1 - 1.9 9.1 11.1 5.2 7.7 3.0 2.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) IBR PF01485.16 OAP59126.1 - 1.3e-09 37.7 25.0 2.7e-05 23.9 4.6 4.5 4 0 0 4 4 4 3 IBR domain FYVE PF01363.16 OAP59126.1 - 0.0058 16.5 33.1 0.25 11.2 4.5 3.9 4 0 0 4 4 4 3 FYVE zinc finger ABC2_membrane PF01061.19 OAP59127.1 - 4.6e-29 101.1 27.4 8.3e-29 100.2 19.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAP59127.1 - 4.5e-25 88.5 0.2 6.7e-25 87.9 0.2 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAP59127.1 - 4.2e-08 33.5 0.1 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 OAP59127.1 - 5.4e-07 29.0 0.2 8.7e-07 28.3 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAP59127.1 - 2.6e-05 24.2 0.1 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAP59127.1 - 0.00032 20.8 0.1 0.0011 19.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAP59127.1 - 0.00036 19.7 0.4 0.0006 19.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 OAP59127.1 - 0.0011 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAP59127.1 - 0.0021 17.4 0.0 0.0062 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 OAP59127.1 - 0.0023 17.0 16.6 0.0023 17.0 11.5 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein SbcCD_C PF13558.1 OAP59127.1 - 0.0026 17.6 0.0 0.0077 16.1 0.0 1.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 OAP59127.1 - 0.0029 17.0 0.2 0.0064 15.9 0.0 1.6 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 OAP59127.1 - 0.003 17.2 0.1 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 OAP59127.1 - 0.0035 17.6 0.0 0.0066 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP59127.1 - 0.0036 18.1 0.0 0.0075 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAP59127.1 - 0.0051 16.2 0.2 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 OAP59127.1 - 0.0057 16.1 0.2 0.22 10.9 0.2 2.2 2 0 0 2 2 2 1 AAA-like domain cobW PF02492.14 OAP59127.1 - 0.0066 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 OAP59127.1 - 0.0067 16.6 0.2 0.026 14.6 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 OAP59127.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 OAP59127.1 - 0.021 14.4 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 OAP59127.1 - 0.026 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 OAP59127.1 - 0.037 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 OAP59127.1 - 0.048 13.3 0.1 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 OAP59127.1 - 0.054 12.3 0.1 0.088 11.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 OAP59127.1 - 0.065 12.9 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 OAP59127.1 - 0.12 10.8 0.0 2.3 6.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 OAP59127.1 - 0.14 10.9 0.1 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.10 OAP59127.1 - 0.2 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Fungal_trans PF04082.13 OAP59128.1 - 1.4e-11 43.7 0.0 2.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59128.1 - 1.5e-09 37.6 7.5 2.8e-09 36.7 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0220 PF05255.6 OAP59130.1 - 0.003 16.8 0.9 0.0049 16.1 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Cytomega_UL20A PF05984.7 OAP59130.1 - 0.18 12.0 0.2 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein CaKB PF03185.10 OAP59130.1 - 0.45 9.8 4.4 0.23 10.8 1.3 1.7 1 1 1 2 2 2 0 Calcium-activated potassium channel, beta subunit TMEM169 PF15052.1 OAP59130.1 - 4.1 7.3 9.8 1.4e+02 2.4 6.8 2.3 1 1 0 1 1 1 0 TMEM169 protein family GST_C PF00043.20 OAP59131.1 - 3.3e-12 46.2 0.0 4.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP59131.1 - 1.6e-11 44.2 0.0 3.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP59131.1 - 5.1e-10 39.2 0.0 1.6e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP59131.1 - 1.2e-09 38.2 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP59131.1 - 3.8e-08 33.1 0.0 6.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP59131.1 - 1.8e-05 25.1 0.0 4e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.19 OAP59132.1 - 2.2e-101 339.6 21.4 2.5e-101 339.4 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59132.1 - 2.6e-24 85.6 34.3 5.4e-19 68.1 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 OAP59132.1 - 0.02 14.6 3.5 0.11 12.2 0.1 2.7 2 0 0 2 2 2 0 Ligand-gated ion channel MatC_N PF07158.6 OAP59132.1 - 0.084 12.6 5.3 0.051 13.3 1.7 2.0 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus NfeD PF01957.13 OAP59132.1 - 0.096 12.8 0.4 0.096 12.8 0.3 3.0 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Alpha-L-AF_C PF06964.7 OAP59133.1 - 3.1e-35 121.5 0.1 4.4e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Fungal_trans PF04082.13 OAP59134.1 - 1.4e-12 47.0 0.1 1.7e-11 43.5 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain CFEM PF05730.6 OAP59136.1 - 3.4e-14 52.3 11.9 4.9e-14 51.8 8.3 1.2 1 0 0 1 1 1 1 CFEM domain DUF1422 PF07226.6 OAP59136.1 - 0.022 14.4 0.4 0.046 13.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) DUF2516 PF10724.4 OAP59136.1 - 0.24 11.4 2.1 0.31 11.0 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) DUF508 PF04370.7 OAP59136.1 - 7.5 6.1 7.3 3.9 7.0 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF508) dCMP_cyt_deam_1 PF00383.17 OAP59137.1 - 7.1e-09 35.2 0.0 1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Cep57_MT_bd PF06657.8 OAP59137.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Glyoxalase_2 PF12681.2 OAP59138.1 - 2e-06 28.3 0.1 2.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP59138.1 - 0.005 16.8 0.0 0.0061 16.5 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SIMPL PF04402.9 OAP59139.1 - 6.4e-21 75.1 0.5 7.1e-21 75.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DAO PF01266.19 OAP59140.1 - 3.3e-53 180.8 0.1 4e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP59140.1 - 6.4e-07 29.6 0.0 4.3e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP59140.1 - 0.00012 21.9 0.1 0.00031 20.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP59140.1 - 0.0029 16.5 0.1 0.022 13.6 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP59140.1 - 0.0084 16.0 0.0 0.077 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP59140.1 - 0.0096 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 OAP59140.1 - 0.014 15.2 0.1 3.1 7.5 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 OAP59140.1 - 0.11 10.9 0.0 4.1 5.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 OAP59140.1 - 0.13 11.1 0.0 0.37 9.6 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3074 PF11274.3 OAP59141.1 - 3.2e-57 193.1 7.7 1.5e-56 190.9 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3074) TPR_MLP1_2 PF07926.7 OAP59141.1 - 0.35 10.6 36.1 0.72 9.5 25.1 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CAF-1_p150 PF11600.3 OAP59141.1 - 0.52 9.6 54.6 0.2 10.9 35.6 2.0 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NAD_binding_1 PF00175.16 OAP59143.1 - 3.3e-26 91.9 0.0 1.1e-25 90.2 0.0 1.9 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 OAP59143.1 - 1e-13 51.2 0.0 4.1e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 OAP59143.1 - 9e-06 25.6 0.0 0.00054 19.9 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain NT-C2 PF10358.4 OAP59144.1 - 2.8e-32 111.1 0.0 4.1e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins T5orf172 PF10544.4 OAP59144.1 - 0.05 13.9 0.5 0.24 11.8 0.1 2.3 3 0 0 3 3 3 0 T5orf172 domain Neur_chan_memb PF02932.11 OAP59144.1 - 3 7.6 5.5 5.4 6.8 3.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLS PF14611.1 OAP59146.1 - 2.8e-12 46.4 0.0 4.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator UPF0242 PF06785.6 OAP59146.1 - 0.029 13.0 0.1 0.049 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Spc42p PF11544.3 OAP59146.1 - 0.095 12.6 0.3 0.3 11.0 0.2 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p Sugar_tr PF00083.19 OAP59147.1 - 6e-68 229.4 20.7 7e-68 229.2 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59147.1 - 4.6e-15 55.2 25.5 4.6e-15 55.2 17.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAP59147.1 - 0.0051 15.2 19.6 0.056 11.8 4.5 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 OAP59148.1 - 1.8e-71 241.0 23.5 2.1e-71 240.8 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59148.1 - 2.4e-15 56.1 33.6 2.4e-15 56.1 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP59148.1 - 0.00097 17.6 4.3 0.00097 17.6 3.0 2.8 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 OAP59148.1 - 0.002 16.3 2.4 0.002 16.3 1.7 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector CstA PF02554.9 OAP59148.1 - 0.11 11.0 16.6 0.091 11.3 2.5 2.1 2 0 0 2 2 2 0 Carbon starvation protein CstA Melibiase PF02065.13 OAP59149.1 - 1e-41 142.9 0.1 5e-21 74.8 0.0 2.1 2 0 0 2 2 2 2 Melibiase Fungal_trans PF04082.13 OAP59150.1 - 4.3e-10 38.9 0.0 2.8e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP59151.1 - 7.4e-17 61.0 41.2 3.6e-12 45.6 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HpcH_HpaI PF03328.9 OAP59153.1 - 6.4e-41 139.6 0.0 7.8e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.13 OAP59154.1 - 1.8e-19 69.6 0.0 2.6e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59154.1 - 0.00024 20.9 9.5 0.00043 20.1 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 OAP59155.1 - 7.3e-38 129.9 1.6 2e-20 73.4 0.0 3.5 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 OAP59155.1 - 2.5e-19 70.3 1.2 0.00017 21.6 0.0 4.4 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 OAP59155.1 - 3.3e-12 46.1 0.6 0.00012 21.4 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 OAP59155.1 - 3.6e-09 36.3 7.0 3.6e-09 36.3 4.8 2.3 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.1 OAP59155.1 - 1.1e-06 28.0 0.1 0.061 12.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Metallophos PF00149.23 OAP59155.1 - 1.4e-06 27.8 2.7 2.9e-06 26.8 1.9 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA_17 PF13207.1 OAP59155.1 - 1e-05 26.3 0.1 0.2 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAP59155.1 - 4.8e-05 22.8 1.1 0.45 9.8 0.6 3.4 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAP59155.1 - 5.7e-05 23.2 0.2 0.19 11.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 OAP59155.1 - 5.8e-05 23.5 6.4 0.056 13.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.1 OAP59155.1 - 5.9e-05 23.0 2.3 0.00034 20.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAP59155.1 - 0.00012 22.4 0.1 0.25 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 OAP59155.1 - 0.00013 22.4 0.0 0.18 12.2 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 OAP59155.1 - 0.00013 21.5 0.0 0.03 13.8 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 OAP59155.1 - 0.00029 20.7 0.1 0.75 9.7 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 OAP59155.1 - 0.00061 18.9 0.0 3 6.7 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_16 PF13191.1 OAP59155.1 - 0.00071 19.5 11.0 0.11 12.5 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 OAP59155.1 - 0.00073 19.4 0.0 0.012 15.4 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 OAP59155.1 - 0.00088 19.1 0.4 1 9.1 0.1 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 OAP59155.1 - 0.00091 18.4 0.1 0.26 10.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 OAP59155.1 - 0.0014 18.3 1.1 3 7.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 OAP59155.1 - 0.0015 17.5 1.2 0.085 11.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA PF00004.24 OAP59155.1 - 0.0025 18.0 1.3 2.3 8.3 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 OAP59155.1 - 0.0031 17.1 0.3 3.1 7.4 0.1 3.0 3 0 0 3 3 3 1 NACHT domain Metallophos_2 PF12850.2 OAP59155.1 - 0.0056 16.5 0.0 0.047 13.5 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain AAA_13 PF13166.1 OAP59155.1 - 0.021 13.3 5.3 3.7 5.8 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 OAP59155.1 - 0.051 13.3 2.3 1.2 8.8 0.1 3.4 3 0 0 3 3 3 0 Part of AAA domain MobB PF03205.9 OAP59155.1 - 0.08 12.6 0.1 7.4 6.2 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 OAP59155.1 - 0.092 12.1 1.0 3.3 7.0 0.2 2.8 3 0 0 3 3 3 0 AAA-like domain Dynamin_N PF00350.18 OAP59155.1 - 1.1 9.0 5.5 2.7 7.7 0.0 3.3 3 1 0 3 3 3 0 Dynamin family ING PF12998.2 OAP59157.1 - 2.1e-05 24.7 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Ras PF00071.17 OAP59158.1 - 1e-55 187.5 0.0 1.6e-55 186.8 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 OAP59158.1 - 2.2e-19 70.1 0.0 3.5e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP59158.1 - 2.4e-13 49.6 0.0 7.3e-13 48.1 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAP59158.1 - 1.7e-06 27.3 0.0 2.6e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAP59158.1 - 2.6e-06 27.0 0.0 6.3e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAP59158.1 - 0.00018 21.4 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAP59158.1 - 0.12 12.5 0.0 0.76 9.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain EI24 PF07264.6 OAP59159.1 - 9e-07 28.5 7.4 2.3e-06 27.1 4.9 2.0 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4185 PF13810.1 OAP59160.1 - 7.8e-06 25.0 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) PAN_4 PF14295.1 OAP59160.1 - 0.0022 17.6 0.3 0.01 15.5 0.2 2.2 1 1 0 1 1 1 1 PAN domain Fungal_trans_2 PF11951.3 OAP59162.1 - 0.0027 16.3 0.0 0.0044 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 OAP59163.1 - 7.8e-22 77.9 1.3 1.4e-21 77.1 0.9 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59163.1 - 3.1e-09 36.7 1.9 5e-09 36.0 0.6 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAP59163.1 - 3.7e-07 30.1 0.0 4.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 OAP59163.1 - 0.088 11.6 0.0 0.41 9.5 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MmgE_PrpD PF03972.9 OAP59164.1 - 1.2e-58 198.4 0.0 1.4e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MFS_1 PF07690.11 OAP59165.1 - 3e-43 147.8 29.4 2e-40 138.6 9.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59165.1 - 7.4e-16 57.7 7.9 7.4e-16 57.7 5.5 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 OAP59165.1 - 3.8e-05 22.0 3.0 3.8e-05 22.0 2.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 OAP59165.1 - 0.00077 19.2 3.6 0.14 11.9 0.1 3.6 2 1 1 3 3 3 2 MFS_1 like family WD40 PF00400.27 OAP59166.1 - 1.9e-07 30.7 3.9 0.12 12.3 0.1 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat PGAP1 PF07819.8 OAP59166.1 - 1.2e-06 28.3 0.0 3.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 OAP59166.1 - 0.00066 19.0 0.0 0.0019 17.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 OAP59166.1 - 0.0022 17.9 0.5 0.012 15.5 0.4 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 OAP59166.1 - 0.0073 15.6 0.1 0.16 11.2 0.0 2.4 2 0 0 2 2 2 1 Lipase (class 2) TFIIIC_delta PF12657.2 OAP59166.1 - 0.0084 15.8 0.0 1.6 8.3 0.0 2.8 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Gmad1 PF10647.4 OAP59166.1 - 0.014 14.8 0.3 0.24 10.7 0.1 2.2 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain LCAT PF02450.10 OAP59166.1 - 0.017 14.1 0.0 0.04 12.8 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase 6PF2K PF01591.13 OAP59166.1 - 0.023 13.7 0.0 0.055 12.5 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Abhydrolase_5 PF12695.2 OAP59166.1 - 0.023 14.4 0.0 0.081 12.6 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Fructosamin_kin PF03881.9 OAP59167.1 - 1.2e-37 129.4 0.0 1.6e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 OAP59167.1 - 9.5e-05 22.2 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Aconitase PF00330.15 OAP59168.1 - 5.4e-57 193.2 0.0 1.8e-52 178.3 0.0 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAP59168.1 - 6.1e-13 49.0 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PEP_mutase PF13714.1 OAP59169.1 - 8.7e-46 156.0 0.1 1e-45 155.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 OAP59169.1 - 2.3e-19 69.0 0.3 3e-19 68.6 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Fungal_trans PF04082.13 OAP59171.1 - 1e-24 86.8 0.6 1.8e-24 86.0 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_6 PF14259.1 OAP59172.1 - 1.8e-07 31.0 0.0 3.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP59172.1 - 0.0007 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP59172.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 OAP59174.1 - 0.00058 20.1 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP59174.1 - 0.02 15.1 0.0 0.86 9.9 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP59174.1 - 0.021 15.3 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) CorA PF01544.13 OAP59175.1 - 2.2e-05 23.6 4.1 5.2e-05 22.4 2.8 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CheF-arch PF04283.7 OAP59175.1 - 0.038 13.2 0.2 0.065 12.4 0.1 1.4 1 0 0 1 1 1 0 Chemotaxis signal transduction system protein F from archaea SecE PF00584.15 OAP59176.1 - 0.00014 21.3 0.9 0.012 15.1 0.0 2.6 3 0 0 3 3 3 2 SecE/Sec61-gamma subunits of protein translocation complex Ripply PF14998.1 OAP59176.1 - 0.13 12.3 0.0 0.54 10.4 0.0 1.8 2 0 0 2 2 2 0 Transcription Regulator WD40 PF00400.27 OAP59177.1 - 7.4e-23 79.5 18.1 5.1e-07 29.3 0.1 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.1 OAP59177.1 - 0.0047 17.1 0.3 12 6.3 0.0 3.8 4 0 0 4 4 4 2 PQQ-like domain Nucleoporin_N PF08801.6 OAP59177.1 - 0.0067 15.2 0.1 4.8 5.8 0.0 3.1 2 1 0 2 2 2 2 Nup133 N terminal like SDA1 PF05285.7 OAP59177.1 - 3.6 6.7 7.3 5.8 6.1 5.1 1.2 1 0 0 1 1 1 0 SDA1 TonB_C PF03544.9 OAP59179.1 - 0.0059 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal Vpu PF00558.14 OAP59181.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Vpu protein Sec39 PF08314.6 OAP59182.1 - 3.7e-143 478.0 2.3 4.3e-143 477.8 1.6 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 OAP59183.1 - 1.6e-05 24.7 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 OAP59183.1 - 0.08 13.0 0.3 0.2 11.7 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UCR_hinge PF02320.11 OAP59183.1 - 0.084 12.8 0.7 0.15 12.0 0.5 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 OAP59183.1 - 1.4 8.9 3.7 0.58 10.2 0.2 1.9 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 OAP59183.1 - 1.8 8.4 4.4 9.9 6.0 0.3 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) DUF3535 PF12054.3 OAP59184.1 - 8.5e-136 453.0 1.4 6e-135 450.2 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 OAP59184.1 - 8.2e-77 257.9 0.0 4.4e-74 248.9 0.0 3.1 2 1 1 3 3 3 1 SNF2 family N-terminal domain HEAT PF02985.17 OAP59184.1 - 7.8e-15 53.5 4.9 0.029 14.4 0.0 8.4 8 0 0 8 8 8 4 HEAT repeat Helicase_C PF00271.26 OAP59184.1 - 2.2e-14 53.0 0.0 4.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 OAP59184.1 - 0.012 16.0 13.1 0.49 10.9 0.1 7.4 8 0 0 8 8 8 0 HEAT-like repeat HEAT_2 PF13646.1 OAP59184.1 - 0.015 15.5 0.1 0.015 15.5 0.1 6.6 10 1 0 10 10 10 0 HEAT repeats Vac14_Fab1_bd PF12755.2 OAP59184.1 - 0.03 14.7 0.0 8.5 6.8 0.0 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 OAP59184.1 - 0.034 13.9 0.5 8.4 6.1 0.0 4.5 6 0 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 RNase_PH PF01138.16 OAP59184.1 - 0.085 13.1 0.3 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 3' exoribonuclease family, domain 1 Cupin_1 PF00190.17 OAP59185.1 - 2.5e-12 46.4 0.2 3.6e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Cupin MAPEG PF01124.13 OAP59186.1 - 1e-18 67.2 0.3 1.5e-18 66.6 0.2 1.3 1 1 0 1 1 1 1 MAPEG family DUF1180 PF06679.7 OAP59186.1 - 0.0014 18.5 0.4 0.0019 18.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) APH PF01636.18 OAP59187.1 - 3.8e-15 56.2 0.1 6.4e-15 55.5 0.0 1.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAP59187.1 - 2.2e-06 27.0 0.4 1.2e-05 24.6 0.2 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 OAP59187.1 - 0.00015 20.5 0.1 0.023 13.3 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 OAP59187.1 - 0.00028 20.5 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Exo_endo_phos PF03372.18 OAP59190.1 - 2.7e-12 47.1 3.1 3.4e-12 46.8 2.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAP59190.1 - 7.6e-06 25.5 0.4 1.2e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Gln-synt_C PF00120.19 OAP59191.1 - 2.1e-42 145.0 0.0 3.7e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 OAP59191.1 - 4e-27 95.4 0.1 7.3e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.17 OAP59192.1 - 1.1e-147 492.1 0.2 1.4e-147 491.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GPI2 PF06432.6 OAP59193.1 - 8.2e-105 350.1 0.4 9.9e-105 349.9 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase adh_short PF00106.20 OAP59194.1 - 1.4e-15 57.6 0.2 3e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59194.1 - 1.6e-06 27.8 0.2 4e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 OAP59194.1 - 0.0016 17.9 0.1 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 OAP59194.1 - 0.0028 17.5 4.8 0.0052 16.6 3.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 OAP59195.1 - 2.1e-81 273.8 18.7 2.3e-81 273.6 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59195.1 - 8e-26 90.5 32.7 9.7e-24 83.7 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_9_N PF15420.1 OAP59195.1 - 0.013 15.2 0.4 0.013 15.2 0.3 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus MFS_1 PF07690.11 OAP59197.1 - 3.3e-45 154.3 21.2 3.3e-45 154.3 14.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59197.1 - 1.6e-08 33.6 3.4 1.6e-08 33.6 2.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter FPN1 PF06963.7 OAP59197.1 - 0.0086 14.5 0.0 0.0086 14.5 0.0 2.0 3 0 0 3 3 3 1 Ferroportin1 (FPN1) MIP-T3 PF10243.4 OAP59198.1 - 1.3e-09 37.1 32.6 1.5e-09 36.9 22.6 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 OAP59198.1 - 5.6 5.1 32.7 8.8 4.4 22.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Fungal_trans PF04082.13 OAP59199.1 - 1.2e-15 57.1 0.1 2.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 OAP59199.1 - 2e-05 24.4 0.5 7.4e-05 22.5 0.4 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP59199.1 - 0.015 14.8 0.2 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pyr_redox_3 PF13738.1 OAP59200.1 - 9.4e-21 74.8 0.0 2.8e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP59200.1 - 4.4e-10 39.7 0.0 1.1e-08 35.2 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP59200.1 - 3.5e-09 36.0 0.3 2e-07 30.2 0.1 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 OAP59200.1 - 1.8e-08 33.0 0.1 4.3e-07 28.5 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP59200.1 - 3.4e-07 30.2 0.0 5.4e-06 26.3 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAP59200.1 - 2.3e-05 24.7 0.3 0.35 11.3 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP59200.1 - 6.7e-05 22.0 0.0 0.0016 17.5 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.13 OAP59200.1 - 0.00056 19.6 0.4 0.61 9.7 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 OAP59200.1 - 0.0023 16.8 0.4 0.0088 14.9 0.1 2.0 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 OAP59200.1 - 0.0058 15.8 0.3 0.025 13.7 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 OAP59200.1 - 0.01 14.7 0.2 0.077 11.8 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP59200.1 - 0.048 12.1 0.1 0.11 10.9 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 OAP59200.1 - 0.071 12.1 0.2 0.29 10.1 0.1 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 OAP59200.1 - 0.072 12.0 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.20 OAP59201.1 - 6.1e-13 49.0 0.0 1e-11 45.0 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59201.1 - 0.0029 17.3 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 2 KR domain Sugar_tr PF00083.19 OAP59202.1 - 2.3e-71 240.7 29.9 2.6e-71 240.5 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59202.1 - 7.5e-21 74.2 38.3 2.3e-10 39.7 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RasGEF PF00617.14 OAP59202.1 - 0.3 10.7 0.5 25 4.5 0.1 2.1 2 0 0 2 2 2 0 RasGEF domain adh_short PF00106.20 OAP59203.1 - 2.9e-25 89.1 2.3 3.8e-25 88.7 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59203.1 - 1.1e-18 67.9 0.0 1.3e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59203.1 - 1.2e-09 38.0 1.8 3.7e-09 36.5 1.2 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP59203.1 - 0.044 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lactamase_B PF00753.22 OAP59204.1 - 1.2e-07 31.5 0.1 2.1e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP59204.1 - 2.7e-05 23.7 0.0 4.6e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.20 OAP59206.1 - 2.1e-15 57.0 0.4 6.3e-15 55.4 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59206.1 - 8e-10 38.6 0.6 1.2e-09 38.1 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP59206.1 - 1.6e-07 31.3 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP59206.1 - 0.0018 17.7 0.4 0.0029 17.0 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP59206.1 - 0.11 12.5 0.3 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 NADH(P)-binding DUF3425 PF11905.3 OAP59207.1 - 3.7e-27 94.8 0.3 6.2e-27 94.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_Maf PF03131.12 OAP59207.1 - 0.095 13.0 4.1 0.2 11.9 2.8 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor NmrA PF05368.8 OAP59208.1 - 7e-25 87.6 0.0 9.6e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP59208.1 - 4.7e-05 23.4 0.0 0.00026 21.0 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP59208.1 - 0.069 11.8 0.1 0.099 11.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAP59208.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 KR domain RhoGAP PF00620.22 OAP59209.1 - 3.1e-47 159.9 0.0 7.6e-47 158.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 OAP59209.1 - 1e-13 51.2 2.3 1.1e-13 51.1 0.1 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Clr5 PF14420.1 OAP59210.1 - 4.5e-15 55.2 0.1 1.2e-14 53.8 0.1 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 OAP59210.1 - 2.9e-10 39.9 0.4 3.4e-06 26.9 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAP59210.1 - 2.6e-08 33.5 3.8 0.033 14.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP59210.1 - 0.00087 19.0 2.6 0.85 9.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAP59210.1 - 0.0018 17.9 0.5 0.055 13.1 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.1 OAP59210.1 - 0.002 17.8 2.4 0.011 15.5 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP59210.1 - 0.051 14.2 1.1 27 5.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP59210.1 - 0.087 12.4 0.1 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 OAP59211.1 - 1.3e-18 66.8 3.5 2.3e-18 66.0 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAP59211.1 - 8.6e-06 25.5 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like APH PF01636.18 OAP59211.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PrmA PF06325.8 OAP59212.1 - 2.3e-10 40.0 0.1 4.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 OAP59212.1 - 1.7e-08 35.0 0.1 1e-07 32.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP59212.1 - 2.4e-08 33.7 0.0 5.7e-08 32.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP59212.1 - 7.5e-08 32.4 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP59212.1 - 1.6e-07 31.7 0.0 5e-07 30.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 OAP59212.1 - 4.7e-07 29.3 0.1 9.4e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 OAP59212.1 - 4.6e-05 23.1 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP59212.1 - 9.4e-05 22.7 0.0 0.00027 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 OAP59212.1 - 0.0003 19.5 0.0 0.00059 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 OAP59212.1 - 0.0025 17.4 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 OAP59212.1 - 0.0042 17.5 0.0 0.0097 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 OAP59212.1 - 0.0069 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 OAP59212.1 - 0.0087 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 OAP59212.1 - 0.023 14.2 0.1 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 FtsJ PF01728.14 OAP59212.1 - 0.032 14.2 0.1 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 OAP59212.1 - 0.05 12.6 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.9 OAP59212.1 - 0.12 11.4 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB FAD_binding_3 PF01494.14 OAP59213.1 - 6.7e-29 101.0 0.0 1.3e-28 100.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP59213.1 - 6.7e-07 29.2 0.3 3.4e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP59213.1 - 4.9e-06 25.6 0.4 0.0001 21.3 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP59213.1 - 2.4e-05 24.6 0.2 0.00068 20.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP59213.1 - 9.1e-05 21.4 0.3 0.00013 20.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP59213.1 - 0.00012 21.9 0.1 0.00042 20.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP59213.1 - 0.0029 17.6 0.0 0.0058 16.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP59213.1 - 0.0029 16.7 0.1 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 OAP59213.1 - 0.0033 16.3 0.0 0.23 10.2 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.9 OAP59213.1 - 0.0042 15.6 0.1 0.019 13.4 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 OAP59213.1 - 0.011 14.7 0.3 0.022 13.7 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 OAP59213.1 - 0.021 13.6 0.3 0.034 13.0 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 OAP59213.1 - 0.054 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 OAP59213.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 OAP59213.1 - 0.11 12.2 0.7 0.51 10.0 0.2 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.11 OAP59214.1 - 1.2e-25 89.9 19.5 1.2e-25 89.9 13.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily HSP70 PF00012.15 OAP59216.1 - 3.7e-07 28.4 0.2 7.6e-07 27.4 0.1 1.5 2 0 0 2 2 2 1 Hsp70 protein Mitofilin PF09731.4 OAP59218.1 - 0.052 12.1 0.0 0.056 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FAD_binding_3 PF01494.14 OAP59219.1 - 1.6e-20 73.5 0.0 9.5e-20 70.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP59219.1 - 8.8e-07 28.8 0.4 1.8e-06 27.8 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP59219.1 - 0.0018 17.2 0.5 0.003 16.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 OAP59219.1 - 0.0052 17.1 0.2 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP59219.1 - 0.0054 15.6 3.4 0.016 14.1 1.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP59219.1 - 0.011 15.5 1.5 0.02 14.7 1.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 OAP59219.1 - 0.014 15.1 0.8 0.031 14.0 0.5 1.6 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 OAP59219.1 - 0.06 12.7 1.1 0.13 11.6 0.4 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 OAP59219.1 - 0.066 13.2 0.4 0.12 12.4 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP59219.1 - 0.074 12.1 1.1 0.14 11.2 0.7 1.5 1 1 0 1 1 1 0 Thi4 family SE PF08491.5 OAP59219.1 - 0.075 11.8 0.0 0.16 10.7 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase GIDA PF01134.17 OAP59219.1 - 0.32 9.7 1.9 0.47 9.2 1.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_43 PF04616.9 OAP59220.1 - 1.8e-28 99.4 2.2 6.3e-19 68.1 0.3 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Amidohydro_3 PF07969.6 OAP59221.1 - 7.5e-60 203.2 3.0 9.8e-60 202.8 2.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 OAP59221.1 - 9.5e-08 32.0 0.0 0.00017 21.3 0.0 3.1 3 1 0 4 4 4 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP59221.1 - 1e-07 31.6 0.1 2.9e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 OAP59221.1 - 0.021 14.8 7.4 0.1 12.6 1.4 3.1 3 1 1 4 4 4 0 Amidohydrolase DUF883 PF05957.8 OAP59222.1 - 0.0094 16.3 2.2 0.013 15.9 0.6 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) SseC PF04888.7 OAP59222.1 - 0.19 11.0 16.4 1.9 7.7 11.3 1.9 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family PhyH PF05721.8 OAP59223.1 - 1.1e-28 100.6 0.3 1.5e-28 100.3 0.2 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 OAP59223.1 - 6.9e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Phosphodiest PF01663.17 OAP59224.1 - 2.7e-30 105.9 0.0 4.3e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.17 OAP59224.1 - 2.7e-06 27.4 0.0 5.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 HD domain HD_4 PF13328.1 OAP59224.1 - 0.039 13.6 0.2 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 HD domain Zn_clus PF00172.13 OAP59225.1 - 7.9e-10 38.4 7.2 1.3e-09 37.7 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP59225.1 - 5.8e-08 31.9 2.1 6.7e-06 25.1 0.2 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Sugar_tr PF00083.19 OAP59226.1 - 3.6e-35 121.4 14.8 4.9e-35 120.9 10.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59226.1 - 6.5e-19 67.8 41.9 3e-17 62.3 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Brix PF04427.13 OAP59228.1 - 1.3e-55 187.9 0.0 1.8e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF1168 PF06658.7 OAP59228.1 - 0.8 9.2 33.1 0.4 10.1 12.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Ndc1_Nup PF09531.5 OAP59228.1 - 5.2 5.3 4.8 7.4 4.8 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UQ_con PF00179.21 OAP59229.1 - 9.4e-41 138.5 0.0 1.1e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP59229.1 - 4e-07 29.8 0.0 5.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAP59229.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF4088 PF13317.1 OAP59229.1 - 0.067 12.5 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) ChAPs PF09295.5 OAP59230.1 - 1.1e-151 505.1 0.0 1.5e-151 504.7 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 OAP59230.1 - 3.2e-06 26.6 0.6 0.12 11.9 0.1 2.8 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 OAP59230.1 - 9.2e-05 21.9 0.2 0.63 9.9 0.1 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP59230.1 - 0.00082 19.1 1.6 0.063 13.2 0.4 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAP59230.1 - 0.0073 15.8 0.6 2 8.1 0.1 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP59230.1 - 0.013 15.7 0.7 9.1 6.7 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat CH PF00307.26 OAP59230.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain TPR_14 PF13428.1 OAP59230.1 - 0.021 15.4 11.4 5.7 7.8 0.1 4.8 3 1 3 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP59230.1 - 0.028 14.3 5.7 5.2 7.0 0.2 4.2 2 2 1 4 4 4 0 Tetratricopeptide repeat DUF1675 PF07897.6 OAP59230.1 - 0.042 13.7 2.9 0.073 12.9 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TPR_7 PF13176.1 OAP59230.1 - 0.051 13.3 2.2 42 4.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 OAP59230.1 - 0.15 11.0 6.1 0.28 10.2 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP59230.1 - 0.34 11.6 3.2 16 6.2 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.11 OAP59231.1 - 2.8 7.8 9.2 2.2 8.1 0.1 4.4 5 0 0 5 5 5 0 Exonuclease VII small subunit PseudoU_synth_1 PF01416.15 OAP59232.1 - 9.5e-25 87.0 0.0 1.2e-17 64.2 0.0 3.9 2 2 0 2 2 2 2 tRNA pseudouridine synthase PIG-H PF10181.4 OAP59233.1 - 2.7e-26 90.9 0.2 4.7e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ubiquitin PF00240.18 OAP59234.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Pribosyl_synth PF14572.1 OAP59235.1 - 2.6e-43 147.9 2.2 2.5e-37 128.4 0.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 OAP59235.1 - 8.9e-32 109.2 0.0 3.3e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 OAP59235.1 - 6.4e-13 48.5 0.4 1.6e-12 47.1 0.3 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAP59235.1 - 0.0028 16.9 1.4 0.0036 16.5 0.1 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Fungal_trans_2 PF11951.3 OAP59236.1 - 2.2e-06 26.5 0.2 4e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59236.1 - 5.2e-06 26.2 5.3 9.7e-06 25.4 3.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 OAP59237.1 - 2.9e-41 141.4 1.2 6.1e-41 140.3 0.8 1.4 1 1 0 1 1 1 1 RTA1 like protein PMP1_2 PF08114.6 OAP59237.1 - 4.2 6.9 7.0 0.18 11.3 0.3 2.1 2 0 0 2 2 2 0 ATPase proteolipid family Closter_coat PF01785.12 OAP59238.1 - 0.094 11.7 0.5 2.3 7.2 0.1 2.1 2 0 0 2 2 2 0 Closterovirus coat protein vATP-synt_AC39 PF01992.11 OAP59239.1 - 6.2e-112 374.0 0.0 7e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SMC_Nse1 PF07574.8 OAP59239.1 - 0.086 12.4 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex GMC_oxred_C PF05199.8 OAP59240.1 - 4e-31 108.2 0.0 7.2e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 OAP59240.1 - 1.2e-27 96.8 0.0 1.7e-24 86.4 0.0 2.9 1 1 1 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.9 OAP59240.1 - 0.002 18.0 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP59240.1 - 0.0085 16.0 0.5 0.026 14.5 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP59240.1 - 0.01 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP59240.1 - 0.014 15.4 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP59240.1 - 0.052 12.4 0.2 0.092 11.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 OAP59240.1 - 0.14 11.1 0.2 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 OAP59240.1 - 0.15 11.1 0.2 0.28 10.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family CFEM PF05730.6 OAP59241.1 - 6e-14 51.6 14.4 1.2e-13 50.5 10.0 1.5 1 0 0 1 1 1 1 CFEM domain Peroxidase_2 PF01328.12 OAP59242.1 - 9.7e-09 34.3 0.2 2e-07 30.0 0.1 2.4 2 0 0 2 2 2 2 Peroxidase, family 2 Fungal_trans PF04082.13 OAP59243.1 - 1.4e-13 50.3 0.0 2.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 OAP59244.1 - 7.1e-51 173.3 0.0 2.4e-50 171.6 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP59244.1 - 5.2e-09 35.4 0.9 0.00014 20.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP59244.1 - 5e-06 25.2 0.0 0.018 13.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 OAP59244.1 - 8.6e-05 22.8 0.5 0.17 12.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP59244.1 - 0.0036 16.4 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 OAP59244.1 - 0.0064 16.5 0.0 0.071 13.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP59244.1 - 0.023 13.6 0.3 0.47 9.3 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein SE PF08491.5 OAP59244.1 - 0.029 13.1 0.0 0.068 11.9 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.1 OAP59244.1 - 0.058 13.4 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP59244.1 - 0.062 12.1 0.0 3.2 6.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.11 OAP59244.1 - 0.14 11.5 0.1 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 OAP59244.1 - 0.17 10.4 0.5 0.55 8.7 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.19 OAP59246.1 - 3e-83 279.8 37.7 3.6e-83 279.6 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59246.1 - 7.9e-32 110.3 27.5 7.9e-32 110.3 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GET2 PF08690.5 OAP59246.1 - 0.058 12.6 0.1 0.058 12.6 0.1 2.5 3 0 0 3 3 3 0 GET complex subunit GET2 APH PF01636.18 OAP59247.1 - 1.4e-38 132.9 0.0 2.1e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAP59247.1 - 0.00025 20.2 0.0 0.00045 19.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 OAP59247.1 - 0.00032 20.1 0.0 0.69 9.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family RMMBL PF07521.7 OAP59247.1 - 0.061 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Choline_kinase PF01633.15 OAP59247.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase p450 PF00067.17 OAP59248.1 - 1.6e-55 188.4 0.0 2e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ROK PF00480.15 OAP59248.1 - 7.2e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 ROK family Lyase_1 PF00206.15 OAP59249.1 - 5e-103 344.5 0.0 9.2e-103 343.6 0.0 1.5 1 0 0 1 1 1 1 Lyase Fungal_trans PF04082.13 OAP59249.1 - 1.4e-22 79.8 0.1 2.2e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FumaraseC_C PF10415.4 OAP59249.1 - 1.4e-13 50.6 0.0 3.7e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Cupin_2 PF07883.6 OAP59251.1 - 3.8e-18 64.7 1.4 1.8e-16 59.3 0.2 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 OAP59251.1 - 9.9e-05 22.0 0.5 0.00025 20.7 0.4 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 OAP59251.1 - 0.00038 19.7 0.2 0.061 12.7 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 OAP59251.1 - 0.0019 17.6 0.0 0.83 9.0 0.0 2.3 2 0 0 2 2 2 2 Cupin FAD_binding_3 PF01494.14 OAP59252.1 - 5.4e-22 78.3 0.1 1.1e-21 77.2 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP59252.1 - 1e-07 31.2 5.8 0.00031 19.7 1.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP59252.1 - 1.5e-06 27.4 0.2 2.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.19 OAP59252.1 - 8e-06 25.1 0.3 0.0017 17.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 OAP59252.1 - 1e-05 25.4 0.1 2.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP59252.1 - 1.2e-05 25.2 0.1 3e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP59252.1 - 9.1e-05 21.0 0.9 0.01 14.3 0.8 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 OAP59252.1 - 0.00021 21.6 3.6 0.0033 17.7 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP59252.1 - 0.00044 19.2 1.2 0.00044 19.2 0.8 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP59252.1 - 0.0087 16.1 0.6 0.073 13.1 0.3 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP59252.1 - 0.02 13.7 2.8 0.031 13.1 1.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 OAP59252.1 - 0.02 13.9 1.2 0.036 13.1 0.3 1.8 2 0 0 2 2 2 0 Thi4 family Rossmann-like PF10727.4 OAP59252.1 - 0.029 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.13 OAP59252.1 - 0.033 13.8 1.7 0.056 13.0 1.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 OAP59252.1 - 0.043 13.3 0.2 0.093 12.2 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 OAP59252.1 - 0.11 12.2 0.5 0.19 11.4 0.4 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 OAP59252.1 - 0.19 11.1 0.5 0.48 9.7 0.4 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 OAP59252.1 - 0.25 9.9 3.2 2 6.9 0.0 2.2 1 1 0 2 2 2 0 Tryptophan halogenase Nop PF01798.13 OAP59253.1 - 3.6e-54 182.1 0.8 3.6e-54 182.1 0.5 2.1 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 OAP59253.1 - 1.2e-26 92.2 0.0 2.1e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 OAP59253.1 - 1e-22 80.0 2.3 1e-22 80.0 1.6 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain HWE_HK PF07536.9 OAP59253.1 - 0.014 15.8 0.1 2.6 8.5 0.0 2.9 2 0 0 2 2 2 0 HWE histidine kinase dsrm PF00035.20 OAP59253.1 - 0.68 10.5 13.6 0.39 11.3 0.2 3.7 3 0 0 3 3 3 0 Double-stranded RNA binding motif RNA_pol_Rpb4 PF03874.11 OAP59254.1 - 1.7e-06 28.0 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb4 PhaG_MnhG_YufB PF03334.9 OAP59254.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 Na+/H+ antiporter subunit PLAC8 PF04749.12 OAP59255.1 - 1.5e-27 96.1 21.3 1.9e-27 95.9 14.8 1.1 1 0 0 1 1 1 1 PLAC8 family Fungal_trans_2 PF11951.3 OAP59257.1 - 2.8e-05 22.9 0.0 5.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP59258.1 - 2.7e-30 105.3 30.1 2.7e-30 105.3 20.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sulfatase PF00884.18 OAP59259.1 - 1.7e-42 145.7 0.0 3.7e-41 141.3 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 OAP59259.1 - 2.2e-09 37.1 0.0 5.3e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 OAP59259.1 - 0.043 14.1 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase FAD_binding_3 PF01494.14 OAP59260.1 - 8.4e-24 84.2 0.1 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP59260.1 - 6.7e-10 38.4 2.2 1.3e-05 24.2 0.7 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP59260.1 - 2.6e-07 29.9 0.4 1.5e-06 27.3 0.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP59260.1 - 1.9e-06 28.0 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP59260.1 - 5e-06 25.6 0.1 7.7e-06 24.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP59260.1 - 8.8e-06 25.6 1.4 1.8e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 OAP59260.1 - 0.00099 18.5 0.1 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 OAP59260.1 - 0.0013 17.4 0.5 0.38 9.3 0.0 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 OAP59260.1 - 0.0041 17.0 0.1 0.0086 15.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP59260.1 - 0.0052 15.6 0.3 0.014 14.3 0.2 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 OAP59260.1 - 0.0086 15.8 0.1 1.5 8.5 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 OAP59260.1 - 0.0095 16.3 0.2 0.18 12.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP59260.1 - 0.01 14.3 0.0 0.022 13.2 0.0 1.6 1 1 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.19 OAP59260.1 - 0.011 14.7 0.2 0.24 10.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 OAP59260.1 - 0.04 13.0 0.1 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 OAP59260.1 - 0.17 10.6 0.0 0.99 8.1 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase Fungal_trans PF04082.13 OAP59261.1 - 9.8e-19 67.2 1.1 1.4e-18 66.7 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59261.1 - 7.7e-05 22.5 3.3 0.00015 21.5 2.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 OAP59262.1 - 3.4e-81 273.1 16.8 4.2e-81 272.8 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59262.1 - 4.2e-17 61.8 17.3 4.2e-17 61.8 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 OAP59264.1 - 3.1e-06 26.0 0.7 3.1e-06 26.0 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4381 PF14316.1 OAP59264.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Kringle PF00051.13 OAP59265.1 - 0.046 13.8 1.0 0.092 12.8 0.7 1.5 1 0 0 1 1 1 0 Kringle domain Peptidase_C1_2 PF03051.10 OAP59267.1 - 1e-155 518.6 0.0 1.3e-155 518.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 OAP59267.1 - 6.2e-09 36.0 0.0 0.00018 21.4 0.0 2.5 3 0 0 3 3 3 2 Papain family cysteine protease UQ_con PF00179.21 OAP59268.1 - 2e-51 173.1 0.0 2.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP59268.1 - 1.2e-05 25.1 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAP59268.1 - 0.037 13.9 0.1 0.07 13.0 0.0 1.7 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 OAP59269.1 - 1.4e-95 319.2 0.9 2e-95 318.7 0.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAP59269.1 - 5.1e-36 122.7 0.7 5.1e-36 122.7 0.5 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAP59269.1 - 8.4e-05 22.1 0.7 0.00021 20.8 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Chal_sti_synt_N PF00195.14 OAP59269.1 - 0.027 13.7 0.8 0.61 9.2 0.0 2.5 2 1 1 3 3 3 0 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.5 OAP59269.1 - 0.84 9.3 7.4 5.6 6.7 0.1 3.2 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III His_Phos_1 PF00300.17 OAP59270.1 - 1.3e-07 31.8 0.0 4.1e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Abhydrolase_6 PF12697.2 OAP59271.1 - 4.6e-15 56.1 0.6 5.9e-15 55.7 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP59271.1 - 3.7e-05 23.5 0.0 8.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Kinesin PF00225.18 OAP59272.1 - 2.9e-107 358.2 0.1 2.9e-107 358.2 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Pro-kuma_activ PF09286.6 OAP59273.1 - 1.2e-29 103.2 0.0 1.7e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAP59273.1 - 2e-07 30.4 0.0 3.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family ABM PF03992.11 OAP59274.1 - 2.2e-06 27.6 1.9 3e-06 27.1 1.3 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MUG113 PF13455.1 OAP59275.1 - 1.9e-23 82.7 1.6 4.3e-23 81.5 1.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 OAP59275.1 - 6.4e-23 81.0 0.3 1.7e-22 79.6 0.2 1.7 1 0 0 1 1 1 1 T5orf172 domain ADH_zinc_N PF00107.21 OAP59276.1 - 4.6e-12 45.5 0.0 9.7e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP59276.1 - 4.4e-08 32.8 0.2 2.5e-06 27.2 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP59276.1 - 1.8e-07 32.0 0.0 5.7e-07 30.4 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 OAP59276.1 - 0.0008 19.4 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding FAD_binding_4 PF01565.18 OAP59277.1 - 1.4e-27 95.8 7.5 2.7e-27 94.9 5.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAP59277.1 - 1.7e-09 37.3 1.8 4.8e-09 35.9 1.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like Peripla_BP_4 PF13407.1 OAP59277.1 - 0.011 15.1 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain Cytokin-bind PF09265.5 OAP59277.1 - 0.13 11.3 0.1 0.3 10.1 0.1 1.5 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding AA_permease_2 PF13520.1 OAP59278.1 - 3.4e-61 207.0 49.2 4.3e-61 206.7 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP59278.1 - 5.4e-20 71.1 40.3 7.3e-20 70.7 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease Cupin_8 PF13621.1 OAP59279.1 - 1.2e-41 142.8 0.0 1.8e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 OAP59279.1 - 3.1e-06 26.6 0.2 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 OAP59279.1 - 2.7e-05 24.3 0.1 5.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 OAP59279.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain RRM_1 PF00076.17 OAP59280.1 - 6.4e-28 96.1 0.1 1.1e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP59280.1 - 3.2e-19 68.6 0.0 1.3e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP59280.1 - 3.2e-14 52.5 0.0 3.5e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAP59280.1 - 0.078 12.8 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif CSD PF00313.17 OAP59280.1 - 0.099 12.4 0.4 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain CENP-B_dimeris PF09026.5 OAP59281.1 - 2.5 8.4 10.1 5.6 7.2 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Homeobox_KN PF05920.6 OAP59282.1 - 1.7e-14 53.2 0.2 4.2e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 OAP59282.1 - 0.0002 21.0 0.3 0.00056 19.6 0.2 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Homeobox PF00046.24 OAP59282.1 - 0.0008 18.9 1.8 0.00083 18.9 0.1 2.0 2 0 0 2 2 2 1 Homeobox domain zf-C2H2 PF00096.21 OAP59282.1 - 0.0021 18.2 17.6 0.032 14.5 0.7 4.6 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP59282.1 - 0.0028 17.8 27.3 0.012 15.9 0.9 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger DUF2614 PF11023.3 OAP59282.1 - 0.26 11.0 0.3 0.55 10.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) UQ_con PF00179.21 OAP59284.1 - 8.5e-08 31.7 0.5 1.6e-07 30.8 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAP59284.1 - 0.033 14.0 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 RWD domain BRE PF06113.7 OAP59284.1 - 0.061 12.3 0.2 0.088 11.8 0.1 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) 2OG-FeII_Oxy_2 PF13532.1 OAP59286.1 - 1.3e-32 113.2 0.0 1.7e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 OAP59286.1 - 1e-08 34.9 6.3 2.3e-08 33.8 4.4 1.6 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 OAP59286.1 - 0.038 14.2 0.0 0.088 13.1 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4387 PF14330.1 OAP59287.1 - 2.7e-26 91.8 0.0 5.4e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 OAP59287.1 - 0.0028 16.1 0.0 0.0041 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Transaldolase PF00923.14 OAP59288.1 - 1e-76 257.8 0.0 1.1e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Sugar_tr PF00083.19 OAP59290.1 - 9.2e-90 301.3 20.6 1.1e-89 301.0 14.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59290.1 - 1.6e-21 76.4 38.5 3.9e-18 65.2 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ox_reductase_C PF08635.5 OAP59291.1 - 4.2e-62 207.7 0.1 6.8e-62 207.0 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 OAP59291.1 - 2e-11 44.4 0.0 3.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP59291.1 - 0.012 15.3 0.0 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.19 OAP59292.1 - 1.1e-84 284.6 28.8 1.3e-84 284.4 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59292.1 - 4.2e-16 58.6 48.6 1.1e-10 40.7 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trypsin_2 PF13365.1 OAP59293.1 - 0.00019 21.4 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Cyclase PF04199.8 OAP59294.1 - 3.1e-08 33.4 0.0 4.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short PF00106.20 OAP59295.1 - 3.1e-20 72.7 6.6 4.3e-13 49.5 0.8 2.6 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59295.1 - 2.8e-19 69.8 0.3 2.6e-13 50.3 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59295.1 - 2.3e-13 50.1 3.9 4.9e-12 45.8 0.4 2.1 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 OAP59295.1 - 0.00024 20.6 0.6 0.00057 19.3 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP59295.1 - 0.00065 19.7 0.3 0.0013 18.8 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP59295.1 - 0.0037 16.5 0.2 0.0061 15.8 0.2 1.4 1 1 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.14 OAP59295.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAP59295.1 - 0.023 14.3 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 OAP59295.1 - 0.028 14.4 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NanE PF04131.9 OAP59295.1 - 0.032 13.2 0.1 0.047 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase YjeF_N PF03853.10 OAP59295.1 - 0.034 13.7 0.4 0.1 12.2 0.3 1.7 1 1 1 2 2 2 0 YjeF-related protein N-terminus DapB_N PF01113.15 OAP59295.1 - 0.036 13.9 0.1 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DFP PF04127.10 OAP59295.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 OAP59295.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glycos_transf_2 PF00535.21 OAP59295.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 Transaldolase PF00923.14 OAP59296.1 - 1.3e-27 96.6 0.1 1.7e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Transaldolase WD40 PF00400.27 OAP59297.1 - 5.7e-29 98.9 18.3 8.2e-10 38.1 0.0 6.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 OAP59297.1 - 0.0039 15.3 1.5 0.064 11.3 0.6 2.5 1 1 2 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.6 OAP59297.1 - 0.0075 15.9 0.0 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 OAP59297.1 - 0.097 12.9 0.3 4.4 7.6 0.1 3.5 3 0 0 3 3 3 0 PQQ-like domain Ribonuclease PF00545.15 OAP59298.1 - 1.2e-16 60.5 0.3 1.6e-16 60.1 0.2 1.2 1 0 0 1 1 1 1 ribonuclease DUF1014 PF06244.7 OAP59299.1 - 3e-24 85.5 7.2 5.5e-24 84.7 4.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Ycf1 PF05758.7 OAP59299.1 - 0.16 9.6 0.9 0.17 9.5 0.6 1.1 1 0 0 1 1 1 0 Ycf1 Gluconate_2-dh3 PF13618.1 OAP59299.1 - 2.2 8.4 11.2 4.7 7.3 7.8 1.5 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 TSA PF03249.8 OAP59299.1 - 3.7 5.9 16.0 5.1 5.5 11.1 1.1 1 0 0 1 1 1 0 Type specific antigen TFIID-18kDa PF02269.11 OAP59300.1 - 8.9e-29 99.1 0.3 1.1e-27 95.6 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 OAP59300.1 - 0.0086 16.1 0.2 0.22 11.6 0.1 2.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAM177 PF14774.1 OAP59300.1 - 0.16 11.8 2.5 0.15 11.9 0.8 1.6 2 0 0 2 2 2 0 FAM177 family TP_methylase PF00590.15 OAP59301.1 - 1e-19 71.0 0.1 2e-19 70.1 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases LamB_YcsF PF03746.11 OAP59302.1 - 4.9e-71 238.6 0.0 5.8e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family AHS2 PF02626.10 OAP59303.1 - 3.3e-77 259.4 0.0 5.1e-77 258.8 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 OAP59303.1 - 1.4e-58 197.6 0.0 2.5e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 OAP59303.1 - 2.8e-35 120.7 0.2 9e-35 119.1 0.1 2.0 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAP59303.1 - 1.7e-34 117.9 0.0 3.4e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain AHS1 PF02682.11 OAP59303.1 - 8e-23 80.9 0.0 1.6e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 OAP59303.1 - 9.2e-14 51.5 0.0 1.6e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 OAP59303.1 - 8.8e-12 44.5 1.1 3.4e-11 42.6 0.5 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 OAP59303.1 - 3.9e-09 35.6 0.0 2.5e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAP59303.1 - 5.7e-07 29.1 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 OAP59303.1 - 1.7e-05 24.3 0.1 0.0072 15.9 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 OAP59303.1 - 8.3e-05 22.1 0.0 0.00036 20.0 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 OAP59303.1 - 0.00046 19.5 0.0 0.00091 18.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 OAP59303.1 - 0.03 13.5 0.0 0.1 11.7 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain PLDc_2 PF13091.1 OAP59304.1 - 1.3e-18 66.9 0.0 2.1e-13 50.1 0.0 3.1 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.17 OAP59304.1 - 6.3e-05 22.6 0.1 0.017 14.9 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF1669 PF07894.7 OAP59304.1 - 0.0012 18.0 0.1 0.26 10.4 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1669) Regulator_TrmB PF11495.3 OAP59304.1 - 0.069 12.1 0.1 0.42 9.5 0.0 2.2 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB p450 PF00067.17 OAP59305.1 - 2e-62 211.2 0.0 2.3e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 OAP59306.1 - 9.8e-21 74.1 0.0 1.4e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP59306.1 - 2.4e-08 34.3 0.0 8.3e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP59306.1 - 1.8e-07 30.8 0.0 2.6e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP59306.1 - 2.9e-07 31.0 0.0 1.7e-06 28.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP59306.1 - 5.8e-05 23.4 0.0 0.00019 21.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP59306.1 - 0.0017 18.3 0.0 0.0051 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP59306.1 - 0.011 16.1 0.0 0.043 14.1 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 OAP59306.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 OAP59306.1 - 0.036 13.6 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) FtsJ PF01728.14 OAP59306.1 - 0.04 13.9 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 OAP59306.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 OAP59306.1 - 0.13 11.6 0.0 0.41 10.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 OAP59308.1 - 1.1e-13 51.2 0.0 8.9e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 OAP59308.1 - 0.00011 22.5 0.0 0.00032 21.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP59308.1 - 0.0063 17.0 0.0 0.018 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP59308.1 - 0.01 16.2 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 OAP59308.1 - 0.013 15.9 0.0 0.085 13.3 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain DAO PF01266.19 OAP59309.1 - 1.4e-49 168.8 0.1 1.7e-49 168.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP59309.1 - 5.9e-05 23.2 0.0 0.012 15.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP59309.1 - 0.00097 18.9 0.4 0.036 13.8 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP59309.1 - 0.0029 17.5 0.0 0.79 9.5 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP59309.1 - 0.01 14.7 0.3 0.056 12.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 OAP59309.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 OAP59309.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.16 OAP59310.1 - 3.8e-70 231.2 0.1 3.7e-35 119.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 OAP59310.1 - 0.00032 20.7 0.0 0.88 9.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ETF_QO PF05187.8 OAP59311.1 - 2.6e-46 156.1 0.0 4.1e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 OAP59311.1 - 5.7e-09 35.3 0.3 0.00031 19.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP59311.1 - 1.7e-07 31.1 0.0 5.5e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP59311.1 - 1.7e-05 24.8 0.1 3.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP59311.1 - 3.1e-05 23.2 0.0 0.00042 19.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 OAP59311.1 - 5.6e-05 22.1 2.3 0.00093 18.1 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 OAP59311.1 - 0.00017 21.4 0.1 0.0013 18.5 0.1 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 OAP59311.1 - 0.00018 20.7 0.2 0.0004 19.5 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 OAP59311.1 - 0.00038 19.0 0.6 0.0006 18.4 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 OAP59311.1 - 0.00042 20.4 0.0 0.00078 19.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP59311.1 - 0.0032 17.8 0.4 3.8 7.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP59311.1 - 0.0088 15.1 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 OAP59311.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 OAP59311.1 - 0.02 13.8 0.2 0.029 13.2 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 OAP59311.1 - 0.087 11.4 0.3 1.4 7.4 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.1 OAP59311.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 OAP59311.1 - 0.16 10.8 0.2 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.20 OAP59312.1 - 9.2e-17 61.4 0.1 1.4e-13 51.1 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59312.1 - 1.5e-07 31.4 0.0 1.2e-05 25.2 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59312.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Fe_hyd_lg_C PF02906.9 OAP59312.1 - 0.031 13.5 0.1 0.068 12.4 0.1 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain adh_short PF00106.20 OAP59313.1 - 1.2e-16 61.1 1.8 1.9e-16 60.4 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59313.1 - 1.3e-06 28.1 0.3 2.2e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP59313.1 - 0.00089 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAP59313.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAP59313.1 - 0.037 13.8 0.8 0.078 12.7 0.1 1.9 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ABC2_membrane PF01061.19 OAP59314.1 - 2.9e-93 310.8 56.1 3.3e-48 163.6 11.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 OAP59314.1 - 1.6e-38 132.1 1.0 4.2e-20 72.4 0.0 3.1 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 OAP59314.1 - 6.1e-30 102.9 0.6 5.3e-26 90.2 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 OAP59314.1 - 1.2e-09 37.6 27.9 2.4e-07 30.1 4.1 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 OAP59314.1 - 2.8e-06 27.3 0.0 1.1e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 OAP59314.1 - 7.2e-06 26.1 2.9 0.015 15.3 1.7 3.6 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 OAP59314.1 - 2.5e-05 23.7 0.3 0.051 12.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 OAP59314.1 - 2.5e-05 23.5 0.2 0.0004 19.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 OAP59314.1 - 0.00013 22.2 0.0 0.0062 16.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP59314.1 - 0.00027 21.0 0.0 0.3 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAP59314.1 - 0.00043 19.7 0.6 0.24 10.9 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 OAP59314.1 - 0.00048 19.6 0.2 0.7 9.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_33 PF13671.1 OAP59314.1 - 0.0006 19.7 0.0 0.033 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP59314.1 - 0.00062 19.8 0.3 0.033 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 OAP59314.1 - 0.0012 19.6 0.0 0.045 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 OAP59314.1 - 0.0013 18.6 0.1 0.0051 16.7 0.1 2.1 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 OAP59314.1 - 0.0027 17.6 0.1 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.14 OAP59314.1 - 0.0031 16.9 0.1 0.027 13.8 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 OAP59314.1 - 0.0039 16.6 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain NACHT PF05729.7 OAP59314.1 - 0.0041 16.7 0.3 0.42 10.2 0.2 2.4 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 OAP59314.1 - 0.007 15.6 0.6 0.053 12.7 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 OAP59314.1 - 0.012 15.1 0.5 0.21 11.2 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 OAP59314.1 - 0.021 13.7 0.1 1.1 8.0 0.2 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 OAP59314.1 - 0.031 14.1 0.5 0.13 12.1 0.0 2.3 3 0 0 3 3 1 0 Dynamin family Septin PF00735.13 OAP59314.1 - 0.069 12.1 0.1 0.25 10.3 0.1 1.8 2 0 0 2 2 2 0 Septin AAA_24 PF13479.1 OAP59314.1 - 0.08 12.5 0.2 0.6 9.6 0.2 2.2 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 OAP59314.1 - 0.14 12.6 0.0 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein PRK PF00485.13 OAP59314.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 OAP59314.1 - 0.17 11.3 1.2 0.28 10.6 0.3 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Cwf_Cwc_15 PF04889.7 OAP59314.1 - 0.21 11.2 4.7 0.17 11.6 0.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AAA_15 PF13175.1 OAP59314.1 - 0.3 10.0 0.0 7.6 5.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 OAP59314.1 - 0.57 8.9 1.9 9.5 4.9 0.3 2.5 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.1 OAP59314.1 - 0.62 9.6 4.5 5.3 6.5 0.3 3.2 3 0 0 3 3 3 0 AAA domain Glyco_hydro_72 PF03198.9 OAP59315.1 - 1.6e-83 280.3 0.3 2.4e-83 279.7 0.2 1.2 1 0 0 1 1 1 1 Glucanosyltransferase GTA_TIM PF13547.1 OAP59316.1 - 0.0045 16.0 0.1 0.0071 15.3 0.1 1.2 1 0 0 1 1 1 1 GTA TIM-barrel-like domain Pkinase PF00069.20 OAP59317.1 - 1.8e-08 33.8 0.0 0.00034 19.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP59317.1 - 7e-06 25.2 0.0 0.0011 18.1 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.2 OAP59319.1 - 7.8e-19 67.8 0.0 6.2e-08 32.8 0.0 4.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP59319.1 - 1.4e-17 63.3 1.8 6.4e-06 26.2 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP59319.1 - 1e-16 60.9 0.5 4.1e-09 36.6 0.0 5.0 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 OAP59319.1 - 2.9e-14 52.0 0.3 0.0058 16.3 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 OAP59319.1 - 1.9e-13 49.1 0.1 0.0029 17.6 0.0 6.2 5 0 0 5 5 5 2 Ankyrin repeat NACHT PF05729.7 OAP59319.1 - 6.5e-10 38.9 0.1 2.2e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP59319.1 - 1.7e-08 34.6 0.6 6.8e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP59319.1 - 1.2e-05 25.4 0.1 0.00017 21.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 OAP59319.1 - 0.00022 20.3 0.1 0.002 17.1 0.0 2.1 1 1 1 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 OAP59319.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase DUF913 PF06025.7 OAP59319.1 - 0.0053 15.5 0.1 0.0094 14.7 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) NB-ARC PF00931.17 OAP59319.1 - 0.07 11.9 0.0 0.16 10.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Methyltransf_11 PF08241.7 OAP59320.1 - 1.9e-09 37.8 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP59320.1 - 9.4e-07 28.5 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP59320.1 - 5.1e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP59320.1 - 0.00047 20.5 0.0 0.0007 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP59320.1 - 0.0007 19.9 0.0 0.0014 18.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PcrB PF01884.12 OAP59320.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 PcrB family adh_short PF00106.20 OAP59321.1 - 0.04 13.8 0.4 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 short chain dehydrogenase HET PF06985.6 OAP59322.1 - 2.3e-11 44.0 0.2 3.5e-10 40.1 0.1 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 OAP59323.1 - 6.1e-34 117.2 43.5 3.1e-32 111.6 21.6 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Aldolase_II PF00596.16 OAP59324.1 - 2e-16 60.1 0.2 2.6e-16 59.7 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain An_peroxidase PF03098.10 OAP59325.1 - 1.2e-72 245.0 0.0 8.9e-55 186.0 0.0 2.3 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 OAP59325.1 - 4.1e-09 35.4 0.0 1.2e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 SspB PF04386.8 OAP59326.1 - 0.36 10.4 2.0 0.81 9.2 1.4 1.5 1 0 0 1 1 1 0 Stringent starvation protein B MIP-T3 PF10243.4 OAP59326.1 - 0.51 8.7 17.6 0.73 8.2 12.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 F-box-like PF12937.2 OAP59326.1 - 1.8 8.3 9.2 0.051 13.3 1.4 2.3 2 1 0 2 2 2 0 F-box-like AAA PF00004.24 OAP59327.1 - 1.7e-40 138.3 0.0 3.7e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAP59327.1 - 6.6e-05 22.6 1.3 0.00024 20.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAP59327.1 - 0.00011 21.2 0.0 0.00041 19.4 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAP59327.1 - 0.0002 21.4 0.5 0.012 15.6 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAP59327.1 - 0.00049 20.2 0.2 0.022 14.8 0.0 2.8 1 1 1 2 2 2 1 AAA domain PhoH PF02562.11 OAP59327.1 - 0.002 17.4 0.2 0.035 13.3 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_2 PF07724.9 OAP59327.1 - 0.0021 18.0 1.8 0.0074 16.2 0.0 2.7 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 OAP59327.1 - 0.0032 16.4 1.2 0.012 14.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 OAP59327.1 - 0.0033 16.6 0.1 0.016 14.3 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 OAP59327.1 - 0.0092 15.8 0.0 0.028 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP59327.1 - 0.013 15.2 0.3 0.036 13.8 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 OAP59327.1 - 0.02 14.3 0.2 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 OAP59327.1 - 0.025 13.9 1.1 0.45 9.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain DUF3608 PF12257.3 OAP59327.1 - 0.032 13.1 0.5 0.052 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) AAA_17 PF13207.1 OAP59327.1 - 0.076 13.8 0.1 0.076 13.8 0.1 3.1 2 2 0 2 2 2 0 AAA domain Herpes_UL25 PF01499.11 OAP59327.1 - 0.17 10.1 1.7 0.25 9.5 1.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family AAA_11 PF13086.1 OAP59327.1 - 0.29 10.6 0.0 0.29 10.6 0.0 2.8 2 2 1 3 3 2 0 AAA domain Cyclin PF08613.6 OAP59328.1 - 1.7e-14 54.5 0.0 2.4e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAP59328.1 - 0.00036 20.1 0.0 0.00063 19.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain CRC_subunit PF08624.5 OAP59329.1 - 7.1e-59 197.6 0.1 1.4e-58 196.7 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit BUD22 PF09073.5 OAP59329.1 - 0.18 10.8 2.6 0.28 10.1 1.8 1.2 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.20 OAP59330.1 - 1.8e-71 240.3 0.0 2.4e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP59330.1 - 1.3e-30 106.3 0.0 1.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAP59330.1 - 7.3e-12 45.6 0.3 3.7e-11 43.3 0.2 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAP59330.1 - 7.7e-09 34.9 0.0 2e-08 33.5 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 OAP59330.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP59330.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 OAP59330.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CsbD PF05532.7 OAP59331.1 - 0.011 15.3 0.6 0.017 14.7 0.4 1.2 1 0 0 1 1 1 0 CsbD-like zf-C2H2_4 PF13894.1 OAP59332.1 - 4.1e-06 26.7 11.8 0.025 14.8 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP59332.1 - 0.0053 17.0 16.6 0.0063 16.7 0.5 3.7 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 OAP59332.1 - 0.0096 16.1 0.2 0.0096 16.1 0.2 3.8 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 OAP59332.1 - 3 8.3 14.4 6.1 7.3 1.4 4.3 4 0 0 4 4 4 0 Zinc-finger double domain Cmc1 PF08583.5 OAP59333.1 - 0.02 14.6 2.5 0.026 14.3 1.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 OAP59333.1 - 0.024 14.0 2.5 1.6 8.1 0.6 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.11 OAP59333.1 - 0.13 12.1 0.8 0.16 11.9 0.6 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein tRNA-synt_1 PF00133.17 OAP59334.1 - 1e-218 727.2 0.2 1.9e-218 726.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAP59334.1 - 3.1e-23 82.2 0.0 5.9e-22 78.0 0.0 2.6 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAP59334.1 - 2.6e-17 62.5 0.2 1.5e-07 30.4 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 OAP59334.1 - 0.002 17.2 0.1 0.046 12.8 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain HET PF06985.6 OAP59335.1 - 5.2e-21 75.2 0.0 1.3e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NAD_binding_2 PF03446.10 OAP59336.1 - 7.7e-31 107.1 0.0 1.3e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP59336.1 - 2.5e-15 56.6 0.1 4.4e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 OAP59336.1 - 0.0054 15.5 0.0 0.0085 14.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 OAP59336.1 - 0.0086 16.4 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Uso1_p115_head PF04869.9 OAP59337.1 - 5.7e-94 314.3 0.0 1.5e-93 312.9 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 OAP59337.1 - 4.5e-05 23.4 42.4 4.5e-05 23.4 29.4 4.0 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region RIX1 PF08167.7 OAP59337.1 - 0.025 14.2 1.3 5.2 6.7 0.0 3.4 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis HEAT PF02985.17 OAP59337.1 - 0.42 10.8 2.9 8 6.8 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Reo_sigmaC PF04582.7 OAP59337.1 - 1 8.4 12.8 0.14 11.3 2.4 2.7 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF3573 PF12097.3 OAP59337.1 - 3.4 6.1 8.1 0.66 8.5 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) NPV_P10 PF05531.7 OAP59337.1 - 9.2 6.5 8.2 3 8.1 0.6 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein AMP-binding PF00501.23 OAP59338.1 - 8e-84 281.4 0.0 1e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP59338.1 - 2.4e-10 41.2 0.0 5.9e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain XRN_N PF03159.13 OAP59339.1 - 2.2e-105 351.3 0.0 2.2e-105 351.3 0.0 1.9 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 OAP59339.1 - 0.033 14.1 3.3 0.076 12.9 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle p450 PF00067.17 OAP59340.1 - 4.4e-53 180.4 0.0 5e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2-Hacid_dh_C PF02826.14 OAP59341.1 - 2.1e-43 147.5 0.0 3.2e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP59341.1 - 1.1e-06 28.1 0.0 2.2e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP59341.1 - 0.045 13.5 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAP59341.1 - 0.092 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.7 OAP59342.1 - 2e-18 66.1 0.1 3.2e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP59342.1 - 8.2e-14 51.2 0.4 2.9e-13 49.5 0.2 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 OAP59342.1 - 0.00046 20.7 0.0 0.0013 19.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 OAP59342.1 - 0.11 12.4 0.2 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding Fungal_trans PF04082.13 OAP59343.1 - 1.3e-11 43.8 0.3 1.3e-11 43.8 0.2 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP59343.1 - 5.6e-06 26.3 1.4 1.5e-05 25.0 1.0 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP59343.1 - 5.1e-05 23.3 1.1 0.00018 21.5 0.7 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger Wyosine_form PF08608.7 OAP59343.1 - 0.095 12.8 2.6 0.096 12.8 0.0 2.3 3 0 0 3 3 3 0 Wyosine base formation zf-H2C2_2 PF13465.1 OAP59343.1 - 0.43 10.9 3.3 1.2 9.5 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double domain tRNA-synt_2b PF00587.20 OAP59344.1 - 2.4e-19 69.5 0.0 3.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 OAP59344.1 - 1.2e-07 31.7 1.4 2.2e-07 30.8 1.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Myosin_tail_1 PF01576.14 OAP59344.1 - 0.038 11.7 0.1 0.049 11.3 0.1 1.0 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 OAP59344.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 IncA protein Abhydrolase_6 PF12697.2 OAP59345.1 - 2.6e-29 102.7 0.5 3.6e-29 102.2 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP59345.1 - 1.6e-16 60.5 0.2 4.1e-16 59.2 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP59345.1 - 1.2e-14 54.2 0.0 3.5e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP59345.1 - 0.0034 17.2 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 OAP59345.1 - 0.087 11.2 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family Epimerase PF01370.16 OAP59346.1 - 1.8e-15 56.9 0.0 2.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP59346.1 - 1.1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP59346.1 - 3.6e-06 26.1 0.0 3.8e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 OAP59346.1 - 0.00072 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 OAP59346.1 - 0.0036 16.0 0.0 0.0064 15.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAP59346.1 - 0.013 14.4 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.5 OAP59346.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 KR domain Fungal_trans PF04082.13 OAP59347.1 - 2.1e-05 23.5 0.0 3.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59347.1 - 0.00081 19.2 11.1 0.0016 18.2 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.16 OAP59348.1 - 3e-39 134.5 2.5 3.4e-39 134.3 1.1 1.5 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain CTP_transf_1 PF01148.15 OAP59349.1 - 4.2e-20 72.5 4.7 1.8e-17 63.8 1.1 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Fructosamin_kin PF03881.9 OAP59350.1 - 9.9e-34 116.6 0.0 1.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 OAP59350.1 - 0.05 13.3 0.1 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_2 PF13360.1 OAP59351.1 - 1.3e-08 34.5 0.0 2.7e-07 30.3 0.0 2.6 2 0 0 2 2 2 1 PQQ-like domain Abhydrolase_6 PF12697.2 OAP59351.1 - 4.4e-06 26.7 0.1 5.1e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP59351.1 - 0.00035 20.2 0.0 0.00075 19.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein WD40 PF00400.27 OAP59351.1 - 0.00057 19.6 0.0 0.34 10.8 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF676 PF05057.9 OAP59351.1 - 0.0017 17.6 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 OAP59351.1 - 0.002 17.9 0.0 0.0062 16.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF359 PF04019.7 OAP59351.1 - 0.01 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF359) NACHT PF05729.7 OAP59351.1 - 0.032 13.9 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF830 PF05708.7 OAP59351.1 - 0.13 12.2 0.0 21 5.0 0.0 2.3 2 0 0 2 2 2 0 Orthopoxvirus protein of unknown function (DUF830) AAA_22 PF13401.1 OAP59351.1 - 0.16 12.1 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 OAP59352.1 - 1.3e-41 142.5 19.3 1.3e-41 142.5 13.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59352.1 - 1.1e-07 30.8 3.8 1.1e-07 30.8 2.6 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 OAP59352.1 - 0.0015 17.0 13.9 0.038 12.4 2.7 2.7 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like Cortexin PF11057.3 OAP59352.1 - 0.0063 16.0 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 Cortexin of kidney UPF0197 PF05251.7 OAP59352.1 - 0.012 15.8 1.2 0.11 12.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0197) DIM PF08194.7 OAP59352.1 - 0.79 9.7 4.1 0.51 10.3 0.3 2.6 2 0 0 2 2 2 0 DIM protein Abhydrolase_6 PF12697.2 OAP59353.1 - 8.9e-28 97.7 3.8 1.4e-27 97.0 2.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP59353.1 - 2.1e-12 46.9 0.2 3.4e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP59353.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Iso_dh PF00180.15 OAP59354.1 - 1.3e-87 294.0 0.0 1.5e-87 293.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EIIA-man PF03610.11 OAP59354.1 - 0.049 13.6 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component Tape_meas_lam_C PF09718.5 OAP59354.1 - 0.15 11.9 0.3 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DEAD PF00270.24 OAP59355.1 - 2.6e-35 121.4 0.1 3.2e-34 117.8 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 OAP59355.1 - 1.2e-20 72.7 0.0 2.3e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 OAP59355.1 - 2.8e-17 62.3 0.0 9.8e-17 60.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP59355.1 - 0.00094 19.0 0.0 0.0058 16.4 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Toprim_3 PF13362.1 OAP59355.1 - 0.075 13.2 0.7 0.27 11.4 0.0 2.3 2 0 0 2 2 2 0 Toprim domain AAA_22 PF13401.1 OAP59355.1 - 0.11 12.6 2.1 0.8 9.8 0.2 2.8 2 1 0 2 2 2 0 AAA domain SPATIAL PF15256.1 OAP59355.1 - 0.81 9.7 5.5 1.6 8.7 3.8 1.4 1 0 0 1 1 1 0 SPATIAL Fungal_trans PF04082.13 OAP59356.1 - 2.4e-32 111.8 0.9 4.5e-32 110.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59356.1 - 1.5e-09 37.5 11.3 2.6e-09 36.8 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP59357.1 - 9.3e-37 126.5 39.5 1e-35 123.1 12.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59357.1 - 8.3e-07 27.9 6.0 8.3e-07 27.9 4.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 OAP59357.1 - 6.2 4.8 13.6 0.64 8.0 4.1 2.6 2 1 0 2 2 2 0 Transmembrane secretion effector CoA_transf_3 PF02515.12 OAP59358.1 - 1.5e-58 197.2 0.1 2.5e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III TRI12 PF06609.8 OAP59359.1 - 8.8e-37 126.5 25.8 1.2e-36 126.1 17.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP59359.1 - 2.1e-21 76.0 51.4 4.2e-21 75.0 33.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59359.1 - 8.4e-10 37.8 38.0 3.7e-09 35.6 7.7 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.13 OAP59360.1 - 2.4e-26 92.1 1.0 2.4e-26 92.1 0.7 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59360.1 - 2.7e-07 30.3 4.5 5.1e-07 29.5 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C14 PF00656.17 OAP59361.1 - 7.2e-45 153.6 0.0 1e-44 153.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 OAP59361.1 - 0.22 11.3 1.0 0.72 9.6 0.1 2.1 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain DUF1628 PF07790.6 OAP59362.1 - 0.012 16.3 0.3 0.027 15.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) DUF3169 PF11368.3 OAP59362.1 - 0.17 11.0 0.1 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Herpes_US9 PF06072.6 OAP59362.1 - 0.18 11.6 1.8 0.31 10.8 1.2 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Ish1 PF10281.4 OAP59365.1 - 4.4e-89 292.0 22.4 4e-14 52.3 0.0 7.9 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 OAP59365.1 - 2.8e-15 55.5 0.0 5.9e-05 22.5 0.0 6.4 6 0 0 6 6 6 4 HeH/LEM domain SAP PF02037.22 OAP59365.1 - 5.5e-12 44.8 0.0 0.099 12.1 0.0 7.3 7 1 0 7 7 7 4 SAP domain APC2 PF08672.6 OAP59365.1 - 1.2e-06 28.6 5.0 9 6.6 0.0 7.1 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.5 OAP59365.1 - 1.7e-06 27.7 1.1 12 5.7 0.0 5.7 7 0 0 7 7 7 1 Slx4 endonuclease LEM PF03020.10 OAP59365.1 - 0.00024 20.4 0.0 2.3 7.7 0.0 4.8 4 0 0 4 4 4 1 LEM domain SAM_2 PF07647.12 OAP59365.1 - 0.0013 18.4 4.0 24 4.8 0.0 5.9 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) DUF2795 PF11387.3 OAP59365.1 - 0.034 14.0 7.9 3.7 7.4 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) DUF3612 PF12268.3 OAP59365.1 - 0.078 12.7 0.0 24 4.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3612) Cyt-b5 PF00173.23 OAP59366.1 - 1.1e-15 57.1 0.0 1.6e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sugar_tr PF00083.19 OAP59367.1 - 2.9e-39 134.9 12.9 7e-39 133.6 8.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59367.1 - 3.4e-24 85.2 17.8 7.1e-24 84.1 12.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SMN PF06003.7 OAP59368.1 - 0.0038 16.3 1.3 0.0067 15.5 0.9 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) AAA_27 PF13514.1 OAP59368.1 - 0.043 11.5 1.0 0.057 11.1 0.7 1.1 1 0 0 1 1 1 0 AAA domain MbeD_MobD PF04899.7 OAP59368.1 - 0.061 13.2 0.8 0.26 11.1 0.5 2.0 1 1 0 1 1 1 0 MbeD/MobD like Lum_binding PF00677.12 OAP59369.1 - 9.6e-35 118.3 0.0 7.6e-18 64.1 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain TPP_enzyme_N PF02776.13 OAP59370.1 - 1.4e-56 190.6 0.0 5.4e-56 188.7 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAP59370.1 - 1.4e-47 161.1 0.4 3.3e-45 153.3 0.0 2.9 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP59370.1 - 1.1e-36 125.6 0.4 4.5e-36 123.6 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain AP2 PF00847.15 OAP59370.1 - 0.05 13.7 2.3 0.061 13.4 0.1 2.2 2 0 0 2 2 2 0 AP2 domain Allantoicase PF03561.10 OAP59371.1 - 6.1e-91 301.7 0.1 9.9e-51 171.1 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.20 OAP59371.1 - 0.031 14.0 0.0 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 F5/8 type C domain MFS_1 PF07690.11 OAP59372.1 - 2.2e-40 138.4 37.9 5.7e-40 137.1 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRAPPC9-Trs120 PF08626.6 OAP59372.1 - 0.18 9.0 0.0 0.25 8.6 0.0 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit AMP-binding PF00501.23 OAP59373.1 - 1.2e-94 317.0 0.0 1.5e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP59373.1 - 9.5e-10 39.2 0.3 3.2e-09 37.6 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GalKase_gal_bdg PF10509.4 OAP59374.1 - 2.3e-19 68.4 0.0 4.6e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 OAP59374.1 - 7.1e-14 51.6 2.2 1.6e-13 50.5 1.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAP59374.1 - 3.5e-12 46.3 0.0 9.1e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF2316 PF10078.4 OAP59374.1 - 0.0014 18.5 0.0 0.27 11.2 0.0 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2316) HTH_7 PF02796.10 OAP59374.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 OAP59374.1 - 0.076 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 OAP59374.1 - 0.09 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.17 OAP59374.1 - 0.12 12.2 0.8 0.34 10.7 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix Phage_antiter_Q PF06323.6 OAP59374.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Phage antitermination protein Q MRP-L28 PF09812.4 OAP59375.1 - 3.1e-07 30.3 0.0 4.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.2 OAP59375.1 - 4.5e-06 26.5 6.7 8e-06 25.7 4.6 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 OAP59375.1 - 3.6e-05 23.6 3.8 6.8e-05 22.7 2.6 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 OAP59375.1 - 0.0028 17.4 5.3 0.0046 16.7 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain Ras PF00071.17 OAP59376.1 - 8.7e-50 168.2 0.0 1e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP59376.1 - 5.1e-17 62.4 0.0 7.1e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP59376.1 - 2.5e-07 30.1 0.0 3.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 OAP59376.1 - 0.0013 17.9 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 OAP59376.1 - 0.007 15.8 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 OAP59376.1 - 0.0093 15.1 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAP59376.1 - 0.077 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase NST1 PF13945.1 OAP59377.1 - 6e-62 209.0 5.2 6e-62 209.0 3.6 4.5 3 1 1 4 4 4 1 Salt tolerance down-regulator GTP1_OBG PF01018.17 OAP59378.1 - 3.9e-35 120.8 5.0 5.1e-26 91.2 3.4 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 OAP59378.1 - 2.1e-19 69.5 0.0 3.7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP59378.1 - 0.00012 21.4 0.1 0.0005 19.3 0.0 2.0 2 1 0 3 3 3 1 Ferrous iron transport protein B ArgK PF03308.11 OAP59378.1 - 0.043 12.5 0.1 1.9 7.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Lactamase_B PF00753.22 OAP59379.1 - 1.7e-05 24.5 0.4 3.5e-05 23.5 0.3 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP59379.1 - 0.0015 18.1 0.5 0.0025 17.3 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Mannosyl_trans3 PF11051.3 OAP59379.1 - 0.034 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Aconitase PF00330.15 OAP59380.1 - 3.1e-162 540.3 0.0 3.6e-162 540.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAP59380.1 - 1.8e-36 125.1 0.0 3.3e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 OAP59380.1 - 0.14 10.6 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Iso_dh PF00180.15 OAP59381.1 - 1.3e-99 333.4 0.0 1.6e-99 333.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.11 OAP59382.1 - 3.4e-33 114.8 21.9 5.3e-33 114.2 15.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 OAP59384.1 - 1.5e-68 231.4 0.0 1.9e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sfi1 PF08457.5 OAP59385.1 - 1.6e-33 115.9 61.1 1.3e-15 56.8 17.8 3.7 1 1 1 2 2 2 2 Sfi1 spindle body protein Glyco_hydro_43 PF04616.9 OAP59386.1 - 5.6e-31 107.6 0.0 7.1e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Arylesterase PF01731.15 OAP59387.1 - 0.0014 18.5 0.1 0.0035 17.3 0.0 1.8 1 1 0 1 1 1 1 Arylesterase Glyco_hydro_42C PF08533.5 OAP59387.1 - 0.063 12.8 0.1 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Transp_cyt_pur PF02133.10 OAP59388.1 - 6.7e-97 324.8 37.9 7.9e-97 324.5 26.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PARP PF00644.15 OAP59390.1 - 3.9e-10 39.4 0.0 7.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 OAP59390.1 - 2.9e-09 36.4 0.0 7.3e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Agouti PF05039.7 OAP59390.1 - 0.031 14.6 0.4 0.097 13.0 0.3 1.8 1 0 0 1 1 1 0 Agouti protein BCSC_C PF05420.6 OAP59390.1 - 0.036 13.2 0.1 0.057 12.5 0.1 1.2 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) RWD PF05773.17 OAP59390.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 RWD domain Wbp11 PF09429.5 OAP59391.1 - 4 7.4 8.6 6.4 6.8 0.4 3.4 3 0 0 3 3 3 0 WW domain binding protein 11 Ribosomal_L27e PF01777.13 OAP59392.1 - 1.8e-38 130.5 4.4 2.4e-38 130.1 3.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 OAP59392.1 - 0.0015 18.1 0.2 0.0042 16.7 0.1 1.8 1 0 0 1 1 1 1 KOW motif Desmo_N PF06771.6 OAP59393.1 - 0.025 14.5 0.7 7.8 6.4 0.1 4.0 2 1 0 3 3 3 0 Viral Desmoplakin N-terminus CMD PF02627.15 OAP59393.1 - 0.079 12.8 3.3 0.35 10.7 0.1 3.7 4 0 0 4 4 4 0 Carboxymuconolactone decarboxylase family TRAM_LAG1_CLN8 PF03798.11 OAP59394.1 - 1.5e-49 168.3 9.8 2e-49 167.8 6.8 1.2 1 0 0 1 1 1 1 TLC domain Mo25 PF08569.6 OAP59395.1 - 1.4e-113 379.3 1.4 2.6e-105 352.1 1.3 2.0 2 0 0 2 2 2 2 Mo25-like Ndc80_HEC PF03801.8 OAP59396.1 - 9.9e-59 197.3 0.0 2e-58 196.3 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF3584 PF12128.3 OAP59396.1 - 2.4e-05 21.9 30.4 3.2e-05 21.5 3.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) IncA PF04156.9 OAP59396.1 - 0.0005 19.7 35.2 0.0015 18.2 12.6 3.0 2 1 0 2 2 2 2 IncA protein Filament PF00038.16 OAP59396.1 - 0.0031 17.0 41.3 0.0063 16.0 15.7 2.6 2 1 0 2 2 2 2 Intermediate filament protein Nucleoporin_FG PF13634.1 OAP59396.1 - 0.0058 16.8 10.0 0.012 15.7 6.9 1.6 1 0 0 1 1 1 1 Nucleoporin FG repeat region CENP-F_leu_zip PF10473.4 OAP59396.1 - 0.019 14.8 43.6 0.18 11.6 13.2 4.2 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 OAP59396.1 - 0.099 12.9 13.4 4.2 7.7 0.1 4.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 OAP59396.1 - 0.13 11.4 3.9 0.52 9.4 0.4 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 OAP59396.1 - 3.6 7.4 16.0 6 6.6 3.5 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Pex14_N PF04695.8 OAP59397.1 - 3.3e-40 137.2 0.0 3.3e-40 137.2 0.0 3.4 3 1 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.3 OAP59397.1 - 0.015 12.6 8.0 0.02 12.2 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 OAP59397.1 - 0.035 11.8 10.2 0.046 11.4 7.1 1.1 1 0 0 1 1 1 0 Myosin tail HAUS5 PF14817.1 OAP59397.1 - 0.037 12.5 4.0 0.053 12.0 2.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Baculo_PEP_C PF04513.7 OAP59397.1 - 0.062 13.1 4.6 0.17 11.6 3.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_N PF02465.13 OAP59397.1 - 0.1 12.9 1.9 0.2 12.0 0.3 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Flagellar_rod PF05149.7 OAP59397.1 - 0.1 11.7 4.4 0.15 11.2 3.0 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein DUF3708 PF12501.3 OAP59397.1 - 0.11 12.2 1.3 0.23 11.3 0.9 1.4 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Rsd_AlgQ PF04353.8 OAP59397.1 - 0.12 12.0 0.7 0.2 11.3 0.3 1.4 1 1 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CR6_interact PF10147.4 OAP59397.1 - 0.17 11.1 3.7 0.11 11.7 1.4 1.5 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TBPIP PF07106.8 OAP59397.1 - 0.32 10.5 4.7 2.2 7.7 2.6 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RRF PF01765.14 OAP59397.1 - 0.42 10.0 6.0 0.69 9.3 4.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor CALCOCO1 PF07888.6 OAP59397.1 - 0.61 8.3 7.8 0.9 7.7 5.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C4H2 PF10146.4 OAP59397.1 - 0.74 9.7 9.8 0.048 13.6 2.5 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein ATP-synt_B PF00430.13 OAP59397.1 - 0.77 9.5 10.3 1.6 8.5 7.1 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) ERM PF00769.14 OAP59397.1 - 0.81 9.1 12.5 0.22 11.0 4.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 OAP59397.1 - 1.4 8.5 10.0 3.2 7.3 6.9 1.6 1 1 0 1 1 1 0 IncA protein DUF4404 PF14357.1 OAP59397.1 - 5.8 7.3 8.3 3.4 8.1 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) TTL PF03133.10 OAP59399.1 - 9.4e-55 185.6 0.0 1.5e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 OAP59399.1 - 3e-46 157.2 0.0 4.5e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 OAP59399.1 - 1e-05 25.3 0.0 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 OAP59399.1 - 3.6e-05 22.7 0.0 0.0011 17.8 0.0 2.5 2 1 0 2 2 2 1 YheC/D like ATP-grasp ABC_tran PF00005.22 OAP59400.1 - 3.5e-33 114.8 0.0 9.7e-33 113.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 OAP59400.1 - 6.9e-15 55.1 7.3 1.2e-14 54.3 5.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 OAP59400.1 - 0.00091 18.5 0.2 0.016 14.4 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP59400.1 - 0.0054 16.7 0.0 0.27 11.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 OAP59400.1 - 0.015 14.8 0.3 0.053 13.0 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 OAP59400.1 - 0.033 13.2 0.0 0.093 11.8 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 OAP59400.1 - 0.035 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAP59400.1 - 0.04 14.0 0.1 0.17 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAP59400.1 - 0.098 12.9 0.0 0.63 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 OAP59400.1 - 0.11 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_17 PF13207.1 OAP59400.1 - 0.12 13.1 0.0 0.42 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 OAP59401.1 - 3.6e-23 81.8 48.3 2.3e-13 49.6 15.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1478 PF07349.6 OAP59402.1 - 0.055 12.8 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) Mu-conotoxin PF05374.7 OAP59404.1 - 2.5 7.9 6.4 1.1 9.0 0.5 2.7 2 0 0 2 2 2 0 Mu-Conotoxin Pkinase PF00069.20 OAP59405.1 - 9.8e-68 228.1 0.0 1.3e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP59405.1 - 3.8e-33 114.6 0.0 5.6e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP59405.1 - 7.3e-06 25.1 0.0 1.9e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 OAP59405.1 - 0.00023 20.3 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP59405.1 - 0.0012 18.5 0.0 0.0075 16.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family PH_3 PF14593.1 OAP59405.1 - 0.066 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 PH domain MFS_1 PF07690.11 OAP59407.1 - 2.6e-38 131.6 33.3 3.5e-38 131.2 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59407.1 - 6.9e-08 31.4 12.1 6.9e-08 31.4 8.4 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 OAP59407.1 - 3.5e-07 28.7 3.0 5.2e-07 28.2 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.1 OAP59407.1 - 3.6 7.6 5.1 17 5.4 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Fungal_trans PF04082.13 OAP59408.1 - 3.9e-23 81.6 0.1 6.9e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59408.1 - 2.1e-07 30.7 10.9 3.8e-07 29.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 OAP59409.1 - 1.4e-25 90.1 0.3 1.9e-25 89.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59409.1 - 2.5e-12 47.1 0.0 3.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59409.1 - 8.6e-07 28.7 0.1 1.3e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP59409.1 - 5.2e-05 23.3 0.1 7.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 OAP59409.1 - 0.035 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.5 OAP59409.1 - 0.081 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3278 PF11683.3 OAP59411.1 - 0.0097 15.8 0.8 0.017 15.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3278) Tmpp129 PF10272.4 OAP59411.1 - 0.11 11.1 0.8 0.17 10.5 0.5 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Asp_protease_2 PF13650.1 OAP59412.1 - 6.6e-05 23.3 0.0 0.00015 22.1 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAP59412.1 - 0.00075 19.3 0.0 0.0019 18.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAP59412.1 - 0.022 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease adh_short_C2 PF13561.1 OAP59414.1 - 2.2e-32 112.7 0.0 2.7e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP59414.1 - 7.3e-31 107.3 1.1 9.1e-31 107.0 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59414.1 - 4e-13 49.4 0.6 5.5e-13 48.9 0.4 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP59414.1 - 0.068 12.5 0.3 0.15 11.4 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAP59415.1 - 1.6e-17 63.9 1.1 1.6e-17 63.9 0.8 1.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59415.1 - 1.2e-14 54.7 0.0 2.7e-14 53.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59415.1 - 3.5e-09 36.5 0.9 1.5e-08 34.4 0.6 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP59415.1 - 3.6e-07 30.3 0.4 1.6e-05 24.9 0.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP59415.1 - 2.8e-06 26.9 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP59415.1 - 0.036 12.9 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.14 OAP59416.1 - 4.9e-49 167.0 0.0 6.8e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP59416.1 - 1.1e-32 113.2 0.2 1.8e-32 112.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAP59416.1 - 2e-05 24.4 0.0 5.5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP59416.1 - 0.00046 19.1 0.0 0.0046 15.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP59416.1 - 0.003 17.6 0.0 2.6 8.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP59416.1 - 0.03 13.2 0.3 0.063 12.1 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAP59416.1 - 0.04 13.7 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP59416.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding NmrA PF05368.8 OAP59418.1 - 1.3e-50 171.8 0.0 1.6e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP59418.1 - 7.1e-13 48.9 0.1 1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP59418.1 - 2.9e-07 29.4 0.0 4.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Kinesin PF00225.18 OAP59419.1 - 6.3e-57 192.7 0.0 1e-56 192.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_C58 PF03543.9 OAP59419.1 - 0.082 12.3 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DUF87 PF01935.12 OAP59419.1 - 0.52 10.0 3.8 6.3 6.5 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Amidohydro_2 PF04909.9 OAP59421.1 - 3.7e-43 148.0 0.2 4.5e-43 147.7 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Lactamase_B_2 PF12706.2 OAP59422.1 - 4.8e-36 124.1 0.2 6.7e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP59422.1 - 8.2e-15 54.8 0.1 1.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAP59422.1 - 0.0014 18.3 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily adh_short PF00106.20 OAP59423.1 - 1.4e-09 38.1 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59423.1 - 0.0007 19.3 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP59423.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF3292 PF11696.3 OAP59424.1 - 9.3e-231 767.1 0.0 1.1e-230 766.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 OAP59424.1 - 7.6e-05 22.2 0.2 0.00042 19.8 0.1 1.9 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.6 OAP59424.1 - 0.21 10.3 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF639 PF04842.7 OAP59424.1 - 0.23 9.5 0.2 0.33 9.0 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3433 PF11915.3 OAP59425.1 - 8.4e-46 154.0 15.9 2.7e-26 91.5 1.2 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Presenilin PF01080.12 OAP59425.1 - 1.6 7.4 7.7 4.6 5.9 0.3 2.4 2 0 0 2 2 2 0 Presenilin Peptidase_S24 PF00717.18 OAP59426.1 - 2.2e-08 33.5 0.0 3.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like SLT PF01464.15 OAP59427.1 - 0.0045 16.4 0.1 0.0083 15.6 0.0 1.5 1 1 0 1 1 1 1 Transglycosylase SLT domain DUF3425 PF11905.3 OAP59428.1 - 5.6e-18 65.1 0.2 9.8e-18 64.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3357 PF11837.3 OAP59429.1 - 0.019 14.8 0.5 0.048 13.5 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF788 PF05620.6 OAP59429.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) CorA PF01544.13 OAP59430.1 - 8.7e-08 31.5 0.5 8.7e-08 31.5 0.4 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Acetyltransf_2 PF00797.12 OAP59431.1 - 2.7e-37 128.6 0.0 3.9e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase adh_short PF00106.20 OAP59432.1 - 0.0024 17.7 0.0 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Tim54 PF11711.3 OAP59432.1 - 0.3 9.6 3.3 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SOBP PF15279.1 OAP59432.1 - 1.6 9.0 36.3 0.28 11.5 22.1 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein Band_7 PF01145.20 OAP59433.1 - 6.7e-27 94.5 2.1 1.3e-26 93.6 1.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family adh_short PF00106.20 OAP59434.1 - 9.3e-17 61.4 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59434.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 KR domain CoA_binding_2 PF13380.1 OAP59434.1 - 0.069 13.3 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 CoA binding domain p450 PF00067.17 OAP59435.1 - 2.7e-54 184.4 0.0 4.1e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UQ_con PF00179.21 OAP59435.1 - 2.2e-21 75.7 0.0 5.2e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EAF PF09816.4 OAP59436.1 - 2.5e-13 49.9 0.0 4.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF726 PF05277.7 OAP59437.1 - 2.2e-115 385.2 1.3 3.1e-115 384.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Trypan_PARP PF05887.6 OAP59437.1 - 0.00041 20.1 11.2 0.00041 20.1 7.7 1.9 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) Abhydrolase_6 PF12697.2 OAP59437.1 - 0.00077 19.4 2.1 0.00077 19.4 1.5 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAP59437.1 - 0.008 16.4 0.4 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 OAP59437.1 - 0.064 13.0 0.2 0.064 13.0 0.2 2.0 1 1 0 2 2 2 0 Alpha/beta hydrolase family TcdA_TcdB_pore PF12920.2 OAP59437.1 - 6.1 4.6 5.3 8.8 4.1 3.7 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Rav1p_C PF12234.3 OAP59438.1 - 1.4e-156 522.3 0.0 2e-156 521.7 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 OAP59438.1 - 2.4 8.1 12.8 5.4 7.0 0.0 5.6 7 0 0 7 7 7 0 WD domain, G-beta repeat Peptidase_C12 PF01088.16 OAP59439.1 - 5.8e-48 162.9 0.0 7.1e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PhyH PF05721.8 OAP59440.1 - 2.9e-18 66.6 0.0 9.8e-18 64.9 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 OAP59440.1 - 0.15 10.5 0.0 0.68 8.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) DUF4096 PF13340.1 OAP59441.1 - 0.026 14.3 0.8 9.7 6.1 0.1 2.6 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) DUF3328 PF11807.3 OAP59442.1 - 5.1e-43 147.2 0.0 5.9e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 OAP59443.1 - 1.2e-18 67.5 0.0 1.7e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF663 PF04950.7 OAP59444.1 - 1.9e-90 302.8 0.0 1.9e-90 302.8 0.0 1.9 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 OAP59444.1 - 6.7e-27 92.8 0.0 1.7e-26 91.5 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 OAP59444.1 - 3.3e-06 26.6 0.0 0.00092 18.6 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAP59444.1 - 3.9e-05 23.7 0.0 0.00013 22.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAP59444.1 - 7.4e-05 22.8 0.0 0.00025 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 OAP59444.1 - 0.00017 21.2 0.1 0.0005 19.7 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAP59444.1 - 0.00027 20.6 0.0 0.00057 19.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 OAP59444.1 - 0.00031 20.6 0.0 0.00087 19.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAP59444.1 - 0.00046 20.6 0.0 0.003 18.0 0.0 2.4 2 0 0 2 2 1 1 Miro-like protein AAA PF00004.24 OAP59444.1 - 0.00052 20.2 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAP59444.1 - 0.00055 19.8 0.0 0.0019 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP59444.1 - 0.00057 20.7 0.0 0.00057 20.7 0.0 4.2 3 1 1 4 4 3 1 AAA domain AAA_19 PF13245.1 OAP59444.1 - 0.00083 19.0 0.2 0.0026 17.4 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 OAP59444.1 - 0.0018 17.7 0.4 0.0088 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 OAP59444.1 - 0.0023 18.2 0.7 0.0081 16.4 0.0 2.2 2 0 0 2 2 1 1 ABC transporter PduV-EutP PF10662.4 OAP59444.1 - 0.0053 16.2 0.0 0.037 13.4 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 OAP59444.1 - 0.0093 15.5 0.1 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 OAP59444.1 - 0.01 15.5 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.14 OAP59444.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 OAP59444.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 OAP59444.1 - 0.017 14.3 0.0 0.04 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 OAP59444.1 - 0.017 14.5 0.0 0.048 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 OAP59444.1 - 0.021 14.7 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 OAP59444.1 - 0.028 13.4 0.0 0.063 12.2 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.1 OAP59444.1 - 0.028 14.7 0.0 0.028 14.7 0.0 2.9 3 0 0 3 3 1 0 AAA domain NB-ARC PF00931.17 OAP59444.1 - 0.032 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 OAP59444.1 - 0.071 12.8 0.2 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 OAP59444.1 - 0.22 11.0 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 OAP59444.1 - 0.24 10.6 0.0 0.79 8.9 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Whi5 PF08528.6 OAP59445.1 - 3.8e-07 29.5 0.2 6.7e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Whi5 like adh_short PF00106.20 OAP59446.1 - 2.5e-22 79.5 2.1 1.3e-20 73.9 1.5 2.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59446.1 - 1.2e-21 77.5 0.2 3.7e-21 75.9 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59446.1 - 0.00024 20.8 0.4 0.0056 16.3 0.2 2.8 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 OAP59446.1 - 0.0012 18.2 0.1 0.0082 15.5 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP59446.1 - 0.002 17.8 0.1 0.0051 16.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 OAP59446.1 - 0.043 13.8 0.2 0.26 11.2 0.2 2.2 1 1 0 1 1 1 0 NADH(P)-binding DFP PF04127.10 OAP59446.1 - 0.055 13.0 0.2 0.14 11.7 0.1 1.7 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein PPO1_KFDV PF12143.3 OAP59446.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) AAA PF00004.24 OAP59447.1 - 1e-16 61.3 0.1 4e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 OAP59447.1 - 6.5e-05 22.6 0.1 0.00016 21.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAP59447.1 - 0.00025 21.2 0.2 0.0015 18.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP59447.1 - 0.00034 21.4 0.0 0.0017 19.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAP59447.1 - 0.0022 17.7 0.0 0.0066 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAP59447.1 - 0.01 15.7 0.1 0.094 12.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAP59447.1 - 0.021 14.8 0.2 0.068 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain PspB PF06667.7 OAP59448.1 - 0.047 13.6 0.3 0.092 12.6 0.2 1.4 1 0 0 1 1 1 0 Phage shock protein B Mrr_N PF14338.1 OAP59448.1 - 0.091 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Mrr N-terminal domain ADH_zinc_N PF00107.21 OAP59449.1 - 3e-16 59.1 0.0 5.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP59449.1 - 0.00043 21.1 0.0 0.00091 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 OAP59449.1 - 0.0049 16.8 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding IBR PF01485.16 OAP59450.1 - 2.9e-11 43.0 52.3 1.5e-06 27.9 8.2 4.6 3 1 1 4 4 4 3 IBR domain Nucleoplasmin PF03066.10 OAP59450.1 - 0.2 11.1 8.2 0.34 10.4 5.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 OAP59450.1 - 4.8 4.9 6.4 5.8 4.7 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family VID27 PF08553.5 OAP59450.1 - 8.3 4.4 5.5 11 4.0 3.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ldh_1_C PF02866.13 OAP59451.1 - 8.8e-45 152.5 0.0 1.3e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 OAP59451.1 - 1.3e-42 144.9 0.0 2e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 OAP59451.1 - 0.0018 17.0 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 OAP59451.1 - 0.04 14.2 0.1 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 OAP59452.1 - 2.4e-23 82.4 23.8 2.4e-23 82.4 16.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59452.1 - 1.4e-07 30.4 8.0 1.4e-07 30.4 5.5 3.6 2 2 0 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 OAP59452.1 - 0.00087 17.5 2.4 0.0012 17.1 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Choline_transpo PF04515.7 OAP59453.1 - 0.021 13.5 7.5 0.31 9.7 1.9 2.5 2 1 0 2 2 2 0 Plasma-membrane choline transporter UCH PF00443.24 OAP59454.1 - 6.3e-81 271.4 0.0 4.1e-80 268.7 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAP59454.1 - 6.4e-18 65.2 0.6 1.1e-09 38.2 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PX PF00787.19 OAP59454.1 - 1.1e-16 60.5 0.0 3.6e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 PX domain DUSP PF06337.7 OAP59454.1 - 1.7e-14 53.9 0.0 7.8e-14 51.8 0.0 2.3 1 0 0 1 1 1 1 DUSP domain Vps5 PF09325.5 OAP59454.1 - 4.6e-09 35.8 8.1 7.1e-08 31.9 0.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Shisa PF13908.1 OAP59454.1 - 0.028 14.5 0.0 0.028 14.5 0.0 3.1 4 0 0 4 4 4 0 Wnt and FGF inhibitory regulator FAM91_N PF14647.1 OAP59454.1 - 0.22 10.5 0.4 12 4.8 0.0 3.0 3 0 0 3 3 3 0 FAM91 N-terminus DUF2428 PF10350.4 OAP59455.1 - 2.3e-54 184.1 0.5 5.1e-54 182.9 0.3 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 OAP59455.1 - 4.4e-05 23.2 11.1 6.2 7.1 0.1 7.5 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 OAP59455.1 - 0.00032 20.9 10.9 0.0045 17.2 0.3 4.9 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 OAP59455.1 - 0.35 11.4 10.1 1.2 9.7 0.1 5.6 5 2 1 6 6 6 0 HEAT-like repeat Tim17 PF02466.14 OAP59456.1 - 1.6e-29 102.5 2.0 2.2e-29 102.1 1.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NAD_binding_10 PF13460.1 OAP59457.1 - 2.6e-16 60.1 0.1 3.9e-15 56.3 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP59457.1 - 1.6e-07 30.3 0.0 8.2e-07 27.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP59457.1 - 1.9e-07 30.7 0.0 6.5e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAP59457.1 - 0.0001 22.2 0.0 0.0061 16.4 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 OAP59457.1 - 0.0017 17.3 0.1 0.14 11.0 0.0 2.6 2 2 1 3 3 3 1 Male sterility protein RmlD_sub_bind PF04321.12 OAP59457.1 - 0.0044 15.9 0.1 0.34 9.7 0.0 2.9 2 1 1 3 3 3 1 RmlD substrate binding domain SYF2 PF08231.7 OAP59458.1 - 1.6e-40 138.6 14.4 1.6e-40 138.6 10.0 1.9 2 1 0 2 2 2 1 SYF2 splicing factor Ribosomal_L20 PF00453.13 OAP59458.1 - 0.55 10.1 5.4 0.53 10.2 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein L20 DAO PF01266.19 OAP59459.1 - 7.1e-21 74.5 0.0 9.6e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP59459.1 - 0.0026 17.7 0.1 0.0066 16.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Saccharop_dh PF03435.13 OAP59459.1 - 0.012 14.5 0.2 0.025 13.5 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase FAD_binding_3 PF01494.14 OAP59459.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 OAP59459.1 - 0.023 15.0 0.0 0.098 13.0 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP59459.1 - 0.033 14.0 0.0 0.072 12.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP59459.1 - 0.057 13.1 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 OAP59459.1 - 0.059 11.9 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase YEATS PF03366.11 OAP59460.1 - 1.2e-34 117.8 0.9 1.8e-34 117.2 0.6 1.3 1 0 0 1 1 1 1 YEATS family Velvet PF11754.3 OAP59462.1 - 7.7e-43 146.4 0.0 1.6e-42 145.4 0.0 1.4 2 0 0 2 2 2 1 Velvet factor Glyoxalase_2 PF12681.2 OAP59463.1 - 5.6e-15 55.8 0.0 6.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP59463.1 - 3.2e-09 36.8 0.0 6.5e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 OAP59463.1 - 6.3e-07 29.3 0.1 7.9e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 OAP59463.1 - 0.0081 16.0 0.2 0.023 14.6 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Lipase_3 PF01764.20 OAP59465.1 - 6.6e-19 67.9 0.0 1.4e-18 66.8 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) 7kD_coat PF02495.12 OAP59465.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 7kD viral coat protein DUF1978 PF09321.5 OAP59466.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Transp_cyt_pur PF02133.10 OAP59468.1 - 9.3e-76 255.1 32.8 1.2e-75 254.8 22.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.16 OAP59469.1 - 2.2e-75 254.2 0.0 2.7e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 OAP59469.1 - 6.4e-35 120.6 0.0 3.1e-34 118.4 0.0 2.0 2 0 0 2 2 2 1 Isochorismatase family Ovate PF04844.8 OAP59469.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcriptional repressor, ovate Fungal_trans PF04082.13 OAP59470.1 - 1.1e-27 96.5 0.1 2.3e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59470.1 - 0.0054 16.6 8.3 0.01 15.7 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP59471.1 - 2.5e-21 75.7 67.3 8.6e-12 44.4 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP59471.1 - 2.1e-05 23.1 12.5 2.1e-05 23.1 8.7 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein Beta-lactamase PF00144.19 OAP59472.1 - 3.4e-57 193.9 0.0 4.3e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.3 OAP59474.1 - 0.64 8.5 4.0 0.32 9.5 0.1 2.3 3 0 0 3 3 3 0 Fungal specific transcription factor domain Atg8 PF02991.11 OAP59475.1 - 8.9e-51 170.1 0.2 1e-50 169.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 OAP59475.1 - 3.1e-06 27.2 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 OAP59476.1 - 2.3e-121 403.9 0.0 4.2e-121 403.0 0.0 1.4 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Cu-oxidase_3 PF07732.10 OAP59477.1 - 3.4e-42 142.8 15.2 4.7e-42 142.4 1.8 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP59477.1 - 8.8e-39 132.1 12.8 6.1e-32 110.0 2.2 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 OAP59477.1 - 1.3e-35 122.6 0.0 6.3e-33 113.9 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Glyco_hydro_16 PF00722.16 OAP59480.1 - 2.7e-10 39.8 0.0 4.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1191 PF06697.7 OAP59480.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) PAT1 PF09770.4 OAP59480.1 - 3.6 5.7 24.6 4.5 5.3 17.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 OAP59480.1 - 3.7 6.8 12.9 4.4 6.6 8.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF2076 PF09849.4 OAP59480.1 - 9.1 6.2 12.4 13 5.7 8.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ferritin_2 PF13668.1 OAP59481.1 - 7.3e-19 68.0 0.0 1.4e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Tmemb_9 PF05434.6 OAP59484.1 - 0.026 14.2 0.3 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 TMEM9 AAL_decarboxy PF03306.8 OAP59486.1 - 9.6e-71 237.3 0.2 1.1e-70 237.1 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.13 OAP59487.1 - 7e-44 149.3 2.4 3.9e-43 146.9 1.7 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAP59487.1 - 1.6e-37 128.4 0.6 8.9e-37 126.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP59487.1 - 1.2e-18 67.1 0.0 4e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF1194 PF06707.6 OAP59487.1 - 0.05 12.5 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Zn_clus PF00172.13 OAP59489.1 - 5.4e-08 32.6 10.6 1.3e-07 31.4 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.10 OAP59490.1 - 9.8e-19 67.1 0.0 1.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Transferase family Asp PF00026.18 OAP59491.1 - 5.1e-31 108.1 0.0 4.6e-30 104.9 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.1 OAP59491.1 - 0.0014 18.3 0.0 0.0095 15.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 OAP59491.1 - 0.0072 15.8 0.0 0.021 14.3 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 OAP59491.1 - 0.0092 16.4 0.2 7.4 7.1 0.0 3.2 3 0 0 3 3 3 1 Aspartyl protease Mob1_phocein PF03637.12 OAP59492.1 - 9.4e-33 113.3 2.5 5.7e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 OAP59493.1 - 7.1e-28 97.4 0.0 1.5e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 Leo1-like protein BAH PF01426.13 OAP59494.1 - 5.5e-17 61.6 0.0 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.1 OAP59494.1 - 7.5e-17 61.3 0.2 7.5e-17 61.3 0.2 3.7 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAP59494.1 - 5.4e-16 58.5 0.3 5.4e-16 58.5 0.2 4.3 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.24 OAP59494.1 - 6.8e-12 44.8 45.5 4.3e-07 29.5 3.5 5.8 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.1 OAP59494.1 - 4.5e-09 35.4 3.0 4.5e-09 35.4 2.1 4.0 5 0 0 5 5 5 2 PHD-finger C1_1 PF00130.17 OAP59494.1 - 0.00022 20.9 2.8 0.00022 20.9 2.0 6.3 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 OAP59494.1 - 0.00089 18.9 5.2 0.00089 18.9 3.6 4.2 4 1 0 4 4 4 1 Prokaryotic RING finger family 1 TrkA_C PF02080.16 OAP59494.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-C domain zf-RING-like PF08746.6 OAP59494.1 - 8.2 6.5 29.4 2 8.4 3.0 4.2 4 0 0 4 4 4 0 RING-like domain DEAD PF00270.24 OAP59495.1 - 9.3e-16 57.7 0.0 4.8e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP59495.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP59495.1 - 0.00024 20.9 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 OAP59495.1 - 0.00086 19.4 0.4 0.0036 17.4 0.0 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA_22 PF13401.1 OAP59495.1 - 0.0025 17.9 0.0 0.0071 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF4332 PF14229.1 OAP59495.1 - 0.0039 17.1 0.4 0.011 15.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4332) AAA_5 PF07728.9 OAP59495.1 - 0.068 12.8 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Flavodoxin_1 PF00258.20 OAP59496.1 - 2.7e-08 33.9 0.1 4.2e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin Zn_clus PF00172.13 OAP59496.1 - 2.5e-07 30.5 9.9 4.4e-07 29.6 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_red PF03358.10 OAP59496.1 - 9.5e-07 28.4 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase APH PF01636.18 OAP59497.1 - 2.2e-36 125.7 0.0 3.6e-36 125.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAP59497.1 - 2.5e-05 23.5 0.0 4.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 OAP59497.1 - 0.00013 21.3 0.0 0.15 11.3 0.1 2.3 2 0 0 2 2 2 2 RIO1 family AMP-binding PF00501.23 OAP59498.1 - 4.9e-71 239.3 0.0 5.9e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP59498.1 - 1.5e-11 45.0 0.0 3.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MaoC_dehydratas PF01575.14 OAP59499.1 - 6.2e-26 90.1 0.0 2.2e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAP59499.1 - 1.1e-10 41.4 0.1 1.7e-06 27.8 0.0 2.7 3 1 0 3 3 3 2 N-terminal half of MaoC dehydratase ECH PF00378.15 OAP59500.1 - 3.8e-31 108.0 0.0 4.3e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DEAD PF00270.24 OAP59501.1 - 2.5e-49 167.0 0.0 9.2e-49 165.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP59501.1 - 1.4e-27 95.3 1.1 2e-25 88.4 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP59501.1 - 3.9e-07 30.0 0.0 8.3e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAP59501.1 - 0.00015 20.6 0.0 0.00027 19.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 OAP59501.1 - 0.0016 17.8 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain DUF1253 PF06862.7 OAP59501.1 - 0.0061 15.0 0.1 0.052 11.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_RecD PF05127.9 OAP59501.1 - 0.008 15.8 0.2 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 Helicase CMS1 PF14617.1 OAP59501.1 - 0.009 15.1 2.5 0.12 11.3 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Rft-1 PF04506.8 OAP59502.1 - 1.5e-81 274.4 4.6 2.8e-81 273.5 3.2 1.3 1 1 0 1 1 1 1 Rft protein Proteasome PF00227.21 OAP59503.1 - 1.3e-44 151.7 0.1 1.8e-44 151.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 OAP59503.1 - 2.5e-14 52.2 2.1 5.7e-14 51.0 1.5 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Sugar_tr PF00083.19 OAP59504.1 - 3.3e-78 263.2 24.3 3.8e-78 263.0 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59504.1 - 5.4e-27 94.4 54.5 3.2e-21 75.4 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HD_4 PF13328.1 OAP59504.1 - 0.019 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 HD domain KH_1 PF00013.24 OAP59506.1 - 1e-38 130.7 2.8 9e-16 57.2 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 OAP59506.1 - 3.9e-29 99.7 9.9 2.2e-11 43.1 1.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 OAP59506.1 - 8.4e-11 41.2 1.0 0.013 15.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 OAP59506.1 - 0.0013 18.4 6.3 1.3 8.9 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.1 OAP59506.1 - 0.0021 17.6 0.2 3.5 7.3 0.1 3.1 3 0 0 3 3 3 2 KH domain Meth_synt_2 PF01717.13 OAP59508.1 - 1.1e-12 47.6 0.0 4.4e-10 39.0 0.0 2.8 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 OAP59508.1 - 0.0019 17.5 0.0 0.0084 15.4 0.0 2.0 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain Sugar_tr PF00083.19 OAP59509.1 - 1.6e-80 270.9 27.0 1.8e-80 270.7 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59509.1 - 5.4e-25 87.8 25.3 1.3e-24 86.5 14.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Ost4 PF10215.4 OAP59509.1 - 3 7.3 6.8 0.41 10.1 0.1 2.9 3 0 0 3 3 3 0 Oligosaccaryltransferase adh_short PF00106.20 OAP59511.1 - 1.8e-21 76.7 2.3 2.7e-21 76.2 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59511.1 - 2.4e-19 70.0 0.2 5.1e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59511.1 - 0.0021 17.7 0.9 0.0033 17.1 0.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP59511.1 - 0.067 12.6 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAP59511.1 - 0.23 11.1 3.0 0.21 11.2 0.8 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DLH PF01738.13 OAP59512.1 - 3.6e-24 85.2 0.0 4.2e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP59512.1 - 6e-05 22.8 0.0 7.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Grp1_Fun34_YaaH PF01184.14 OAP59513.1 - 6.4e-31 107.2 17.2 9e-31 106.8 11.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family HET PF06985.6 OAP59515.1 - 0.00012 22.2 0.1 0.045 13.8 0.0 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DSPc PF00782.15 OAP59517.1 - 2.4e-09 36.8 0.0 4.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAP59517.1 - 1.8e-06 27.4 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 OAP59517.1 - 0.026 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 OAP59517.1 - 0.032 14.2 0.0 0.098 12.6 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate PTEN_C2 PF10409.4 OAP59517.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein MFS_1 PF07690.11 OAP59518.1 - 2.4e-44 151.4 70.4 9.3e-42 142.9 35.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 OAP59518.1 - 0.0023 16.0 8.1 0.041 11.9 0.8 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2404 PF10296.4 OAP59519.1 - 0.00039 20.4 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF2683 PF10884.3 OAP59519.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) DUF2763 PF10961.3 OAP59519.1 - 5.7 7.3 7.4 31 5.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) ARD PF03079.9 OAP59521.1 - 5.2e-47 159.6 0.4 6.4e-47 159.4 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 OAP59521.1 - 4e-09 35.8 0.0 7e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 OAP59521.1 - 5.9e-06 25.9 0.0 9.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 OAP59521.1 - 0.0033 16.8 0.0 0.0057 16.0 0.0 1.6 1 1 0 1 1 1 1 Cupin DUF4078 PF13300.1 OAP59521.1 - 0.042 13.9 1.8 0.59 10.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4078) adh_short PF00106.20 OAP59522.1 - 3.4e-19 69.3 0.0 5.1e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59522.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP59522.1 - 3.2e-05 23.5 0.0 6.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP59522.1 - 0.0061 15.4 0.0 0.0081 15.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 OAP59522.1 - 0.007 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 OAP59522.1 - 0.021 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 OAP59522.1 - 0.03 14.2 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 OAP59522.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding CDC45 PF02724.9 OAP59522.1 - 7.3 4.4 5.3 37 2.1 4.3 1.6 2 0 0 2 2 2 0 CDC45-like protein BRE1 PF08647.6 OAP59523.1 - 2.9e-22 78.4 8.6 2.9e-22 78.4 6.0 6.3 5 1 0 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 OAP59523.1 - 2.7e-08 33.7 9.8 4.8e-08 32.8 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP59523.1 - 1.4e-07 31.0 10.7 2.6e-07 30.1 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP59523.1 - 4.5e-07 29.4 6.8 8e-07 28.6 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP59523.1 - 1.5e-05 24.6 10.0 2.7e-05 23.8 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAP59523.1 - 2e-05 24.3 6.5 4.3e-05 23.2 4.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 OAP59523.1 - 0.0006 19.4 5.6 0.0019 17.8 3.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger DUF1272 PF06906.6 OAP59523.1 - 0.0006 19.5 6.1 0.0013 18.4 4.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 OAP59523.1 - 0.0025 17.6 6.7 0.0049 16.7 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DZR PF12773.2 OAP59523.1 - 0.024 14.4 6.5 0.048 13.4 4.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon Cast PF10174.4 OAP59523.1 - 0.04 11.9 68.2 0.29 9.1 22.7 3.6 2 2 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone zf-RING_4 PF14570.1 OAP59523.1 - 0.057 13.0 6.7 0.12 11.9 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 OAP59523.1 - 0.067 13.3 4.1 0.14 12.2 2.0 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_6 PF14835.1 OAP59523.1 - 0.14 11.9 2.5 0.27 11.0 1.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein APG6 PF04111.7 OAP59523.1 - 0.48 9.4 79.1 0.063 12.3 0.6 6.0 3 1 3 6 6 6 0 Autophagy protein Apg6 IncA PF04156.9 OAP59523.1 - 0.5 9.9 80.1 0.045 13.3 9.4 5.9 2 1 5 7 7 7 0 IncA protein CENP-F_leu_zip PF10473.4 OAP59523.1 - 0.67 9.8 71.1 0.52 10.1 0.3 6.7 3 1 3 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 OAP59523.1 - 2.7 8.3 58.5 1 9.7 4.6 7.6 4 2 3 7 7 6 0 Protein of unknown function (DUF972) FYVE PF01363.16 OAP59523.1 - 4 7.3 10.2 6 6.8 3.8 2.6 1 1 1 2 2 2 0 FYVE zinc finger KxDL PF10241.4 OAP59523.1 - 4.3 7.2 35.2 0.02 14.8 3.7 5.6 4 1 1 5 5 5 0 Uncharacterized conserved protein ADIP PF11559.3 OAP59523.1 - 5.6 6.8 79.0 0.05 13.5 5.4 7.2 5 2 2 7 7 7 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 OAP59523.1 - 7.6 6.3 42.2 0.19 11.4 3.1 8.4 8 0 0 8 8 8 0 Homeobox associated leucine zipper UreF PF01730.11 OAP59525.1 - 4.2e-12 46.3 0.1 7.1e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 UreF ABC1 PF03109.11 OAP59526.1 - 7.2e-33 113.0 0.0 1.4e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family AMPKBI PF04739.10 OAP59527.1 - 9.4e-26 89.6 0.3 9.4e-26 89.6 0.2 2.3 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain RelB PF04221.7 OAP59527.1 - 0.067 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 RelB antitoxin Peptidase_M22 PF00814.20 OAP59528.1 - 2.5e-84 282.9 0.0 2.9e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family SET PF00856.23 OAP59529.1 - 3.3e-14 53.5 0.0 9.2e-14 52.0 0.0 1.7 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 OAP59529.1 - 2.1e-05 24.4 0.1 0.00037 20.4 0.0 2.4 1 1 1 2 2 2 1 Rubisco LSMT substrate-binding EPL1 PF10513.4 OAP59530.1 - 7.2e-34 117.3 3.6 1e-32 113.6 0.2 2.5 2 1 0 2 2 2 2 Enhancer of polycomb-like CCDC32 PF14989.1 OAP59530.1 - 0.038 13.8 1.6 0.082 12.7 1.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing 32 EF-hand_1 PF00036.27 OAP59531.1 - 9.1e-26 87.1 16.2 1e-07 30.7 0.2 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 OAP59531.1 - 1.3e-22 79.7 4.0 1.2e-12 47.7 0.3 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 OAP59531.1 - 1.4e-18 64.9 10.1 5.3e-05 22.7 0.0 4.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 OAP59531.1 - 8.2e-18 62.8 15.6 2.4e-06 26.5 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 OAP59531.1 - 1.1e-12 47.3 14.7 6.8e-05 22.4 0.4 4.8 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 OAP59531.1 - 2.9e-06 27.3 0.0 0.0039 17.1 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 OAP59531.1 - 5e-05 22.9 8.4 0.075 12.7 0.2 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Anthrax-tox_M PF09156.5 OAP59531.1 - 0.049 12.7 0.7 0.19 10.7 0.1 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain EF-hand_9 PF14658.1 OAP59531.1 - 0.12 12.3 0.1 1.3 8.9 0.0 2.5 2 1 1 3 3 3 0 EF-hand domain Iso_dh PF00180.15 OAP59532.1 - 2.3e-105 352.3 0.0 3e-105 352.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short PF00106.20 OAP59534.1 - 4.4e-16 59.2 1.2 7.2e-16 58.5 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP59534.1 - 2.9e-07 30.3 0.0 4.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP59534.1 - 9.5e-05 21.9 0.2 0.0015 18.0 0.1 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF3073 PF11273.3 OAP59534.1 - 0.14 12.7 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) DUF544 PF04424.8 OAP59535.1 - 3e-13 49.6 0.0 4.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Cyclin_N PF00134.18 OAP59536.1 - 0.18 11.3 0.1 0.45 10.0 0.0 1.7 1 0 0 1 1 1 0 Cyclin, N-terminal domain VID27 PF08553.5 OAP59536.1 - 0.58 8.3 2.1 1.5 6.9 1.5 1.6 1 0 0 1 1 1 0 VID27 cytoplasmic protein DS PF01916.12 OAP59537.1 - 1.5e-139 464.2 0.0 1.8e-139 464.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 OAP59537.1 - 0.04 13.0 0.1 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase zf-C3HC4_3 PF13920.1 OAP59538.1 - 4.9e-11 42.1 14.6 8e-11 41.4 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 OAP59538.1 - 1.3e-08 34.3 0.0 1.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 OAP59538.1 - 5.7e-08 32.2 0.0 0.00079 18.7 0.0 2.3 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C3HC4_2 PF13923.1 OAP59538.1 - 0.002 18.1 15.5 0.0044 17.0 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.15 OAP59538.1 - 0.023 14.3 0.7 0.023 14.3 0.5 4.3 4 0 0 4 4 4 0 MORN repeat Acyl-CoA_dh_M PF02770.14 OAP59538.1 - 0.067 12.7 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain zf-RING_5 PF14634.1 OAP59538.1 - 0.26 11.0 16.2 0.5 10.1 11.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Abhydrolase_6 PF12697.2 OAP59539.1 - 5.2e-24 85.4 0.0 5.9e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP59539.1 - 5.7e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 OAP59540.1 - 2.7e-09 37.1 0.1 2.6e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase MFS_1 PF07690.11 OAP59541.1 - 5.8e-36 123.9 33.1 1.6e-35 122.4 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Romo1 PF10247.4 OAP59541.1 - 0.044 13.9 2.2 0.45 10.7 0.0 3.4 3 1 1 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 Septin PF00735.13 OAP59542.1 - 3.3e-36 124.7 0.0 1.2e-12 47.4 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.18 OAP59542.1 - 0.002 18.0 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase CDC45 PF02724.9 OAP59542.1 - 0.0035 15.4 0.5 0.0047 15.0 0.3 1.2 1 0 0 1 1 1 1 CDC45-like protein FtsK_SpoIIIE PF01580.13 OAP59542.1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TEX19 PF15553.1 OAP59542.1 - 0.061 13.1 0.4 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 Ras PF00071.17 OAP59542.1 - 0.062 12.6 0.0 0.3 10.4 0.0 2.0 1 1 0 1 1 1 0 Ras family AAA_14 PF13173.1 OAP59542.1 - 0.065 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 OAP59542.1 - 0.08 13.4 0.1 0.35 11.3 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein Nop14 PF04147.7 OAP59542.1 - 0.18 9.6 6.4 0.27 9.0 4.5 1.2 1 0 0 1 1 1 0 Nop14-like family HnRNP_M PF11532.3 OAP59543.1 - 0.045 13.8 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M DOPA_dioxygen PF08883.6 OAP59544.1 - 2e-32 111.3 0.0 2.4e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF2348 PF09807.4 OAP59545.1 - 1.2e-06 27.8 0.0 0.0087 15.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) Phosphoprotein PF00922.12 OAP59545.1 - 1 8.4 3.6 1.6 7.8 2.5 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Glyco_hydro_16 PF00722.16 OAP59546.1 - 2.2e-37 128.1 0.7 7.6e-37 126.3 0.5 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 LysM PF01476.15 OAP59546.1 - 4.5e-18 64.8 0.1 6.4e-09 35.5 0.0 2.7 3 0 0 3 3 3 2 LysM domain DUF814 PF05670.8 OAP59548.1 - 7.7e-17 60.9 0.0 1.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) TBCC PF07986.7 OAP59548.1 - 0.14 11.5 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor C OmpH PF03938.9 OAP59548.1 - 0.36 10.7 5.1 0.48 10.3 3.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1682 PF07946.9 OAP59548.1 - 8.5 5.1 13.1 12 4.6 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Seipin PF06775.9 OAP59549.1 - 0.068 12.6 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) FAM176 PF14851.1 OAP59549.1 - 0.14 11.8 2.9 0.076 12.7 0.3 1.8 2 0 0 2 2 2 0 FAM176 family Thiolase_C PF02803.13 OAP59550.1 - 1.1e-12 47.4 0.3 3.4e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 OAP59550.1 - 4e-08 32.8 0.0 4.7e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 OAP59550.1 - 1.3e-07 30.8 0.0 6.5e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 OAP59550.1 - 3.5e-05 23.4 0.2 0.00019 20.9 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 OAP59550.1 - 0.011 15.5 0.4 0.12 12.2 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DFP PF04127.10 OAP59550.1 - 0.088 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Mito_carr PF00153.22 OAP59551.1 - 2.8e-45 151.9 6.6 5.6e-15 54.8 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Oxidored_FMN PF00724.15 OAP59552.1 - 1.7e-45 155.5 0.0 2.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF202 PF02656.10 OAP59553.1 - 2.8e-15 56.2 1.9 2.8e-15 56.2 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ACR_tran PF00873.14 OAP59553.1 - 0.087 10.2 0.0 0.1 9.9 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family PDEase_I PF00233.14 OAP59555.1 - 1.3e-47 162.6 0.1 4.2e-43 147.7 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase NPL4 PF05021.10 OAP59556.1 - 2.1e-127 424.5 0.0 2.6e-127 424.2 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 OAP59556.1 - 1.7e-73 245.1 0.5 2.5e-73 244.6 0.4 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 OAP59556.1 - 0.029 14.6 0.0 0.52 10.6 0.0 2.4 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF2417 PF10329.4 OAP59557.1 - 7.4e-83 277.4 2.0 1e-82 277.0 1.4 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 OAP59557.1 - 6.4e-06 26.2 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Spo7 PF03907.8 OAP59557.1 - 0.0047 16.5 0.5 0.01 15.4 0.3 1.4 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 OAP59558.1 - 2.8e-23 83.0 0.1 4.2e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP59558.1 - 3.3e-10 39.9 0.1 0.00077 19.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP59558.1 - 3.4e-09 36.5 0.0 6.3e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP59558.1 - 0.0027 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 OAP59558.1 - 0.03 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 OAP59558.1 - 0.039 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 OAP59558.1 - 0.043 13.3 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 OAP59558.1 - 0.09 12.0 0.0 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF3089 PF11288.3 OAP59558.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DEAD PF00270.24 OAP59559.1 - 2.1e-43 147.7 0.0 4.8e-43 146.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP59559.1 - 6.5e-23 80.4 0.0 2.2e-22 78.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MCPsignal PF00015.16 OAP59559.1 - 0.0025 17.4 3.2 0.0058 16.1 2.2 1.6 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1253 PF06862.7 OAP59559.1 - 0.0076 14.6 0.4 0.25 9.6 0.0 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) Pribosyltran PF00156.22 OAP59560.1 - 6.1e-15 55.0 0.0 8.5e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAP59560.1 - 0.058 12.5 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase AMP-binding PF00501.23 OAP59561.1 - 3.8e-59 200.1 1.7 2.1e-23 82.4 0.6 4.6 3 1 0 3 3 3 3 AMP-binding enzyme ADH_N PF08240.7 OAP59561.1 - 8.4e-29 99.5 1.0 2e-28 98.3 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP59561.1 - 1e-15 57.4 0.0 2.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DMAP_binding PF06464.6 OAP59561.1 - 3.5e-10 40.4 0.1 1.4e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 DMAP1-binding Domain ADH_zinc_N_2 PF13602.1 OAP59561.1 - 0.0026 18.6 0.0 0.0099 16.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP59561.1 - 0.0035 16.9 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1212 PF06738.7 OAP59563.1 - 2.5e-38 131.5 7.6 6.5e-34 117.0 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 OAP59563.1 - 4.4e-28 97.8 12.6 4.4e-28 97.8 8.8 3.1 2 1 0 3 3 3 2 Protein of unknown function (DUF3815) Abhydrolase_3 PF07859.8 OAP59564.1 - 1.5e-54 184.8 0.0 1.8e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP59564.1 - 6.8e-07 28.3 1.0 2.4e-06 26.5 0.7 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 OAP59564.1 - 1.5e-06 28.2 0.3 3.2e-06 27.2 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP59564.1 - 4e-06 26.6 0.0 5.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 OAP59564.1 - 0.0016 17.1 0.0 0.0033 16.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydro_lipase PF04083.11 OAP59564.1 - 0.0017 17.6 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Peptidase_S9 PF00326.16 OAP59564.1 - 0.0022 17.2 0.1 0.014 14.6 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 OAP59564.1 - 0.0036 16.6 0.1 0.0071 15.6 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 OAP59564.1 - 0.023 13.2 0.0 0.036 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CoA_transf_3 PF02515.12 OAP59565.1 - 9.9e-63 210.8 0.0 1.6e-62 210.1 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III Ribonuc_L-PSP PF01042.16 OAP59566.1 - 5e-39 132.8 0.0 5.5e-39 132.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ADH_zinc_N PF00107.21 OAP59567.1 - 1.6e-29 102.0 0.2 3.1e-29 101.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP59567.1 - 3.1e-10 41.0 0.0 8.5e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP59567.1 - 9.2e-08 31.8 0.0 4.6e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 OAP59567.1 - 0.0014 18.2 0.2 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HupF_HypC PF01455.13 OAP59567.1 - 0.011 15.6 0.2 0.045 13.7 0.1 2.1 1 1 0 1 1 1 0 HupF/HypC family Ifi-6-16 PF06140.8 OAP59569.1 - 0.0022 17.7 33.0 0.0022 17.7 22.9 2.4 1 1 1 2 2 2 1 Interferon-induced 6-16 family BNR PF02012.15 OAP59570.1 - 0.00066 19.1 1.0 2.7 8.1 0.0 3.6 2 0 0 2 2 2 2 BNR/Asp-box repeat NMO PF03060.10 OAP59571.1 - 6e-69 232.7 1.2 7.2e-69 232.4 0.8 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAP59571.1 - 9.2e-07 28.0 1.0 0.013 14.4 0.0 2.5 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAP59571.1 - 0.00015 20.7 1.1 0.00015 20.7 0.8 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 OAP59571.1 - 0.0039 16.1 0.1 0.0063 15.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 OAP59571.1 - 0.063 12.2 0.3 0.12 11.3 0.2 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase MFS_1 PF07690.11 OAP59572.1 - 1.6e-31 109.3 28.3 3e-31 108.4 19.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP59572.1 - 4.7e-05 22.4 0.3 9.9e-05 21.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.12 OAP59573.1 - 1.4e-37 128.8 0.0 9.3e-35 119.6 0.0 2.4 2 0 0 2 2 2 2 CoA-transferase family III Fungal_trans PF04082.13 OAP59574.1 - 9.6e-27 93.4 0.2 1.7e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59574.1 - 3.2e-09 36.5 8.4 5.2e-09 35.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 OAP59575.1 - 3.1e-31 109.0 0.0 3.8e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP59575.1 - 1.3e-26 93.4 1.4 1.6e-26 93.1 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59575.1 - 6.7e-06 25.8 0.4 1.1e-05 25.1 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP59575.1 - 0.0067 15.8 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP59575.1 - 0.018 14.8 2.0 0.039 13.7 1.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_3 PF13738.1 OAP59576.1 - 2.5e-19 70.1 0.1 1.6e-18 67.5 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP59576.1 - 1.1e-14 53.5 1.7 4e-14 51.7 0.3 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP59576.1 - 3.8e-07 29.3 0.0 4.4e-05 22.5 0.1 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP59576.1 - 0.00024 21.0 0.1 0.00093 19.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP59576.1 - 0.021 14.6 0.0 0.52 10.1 0.0 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP59576.1 - 0.035 13.8 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding adh_short PF00106.20 OAP59577.1 - 1.3e-19 70.6 0.1 1.8e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59577.1 - 9.7e-11 41.8 0.0 1.3e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59577.1 - 1.3e-06 28.2 0.1 7e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP59577.1 - 2.7e-05 23.7 0.0 0.0002 20.8 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Retrotrans_gag PF03732.12 OAP59577.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein 3Beta_HSD PF01073.14 OAP59577.1 - 0.01 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 OAP59578.1 - 6.7e-28 97.4 32.3 6.7e-28 97.4 22.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.13 OAP59578.1 - 0.0068 14.9 2.3 0.0068 14.9 1.6 2.0 3 0 0 3 3 3 1 Reduced folate carrier Lactamase_B PF00753.22 OAP59579.1 - 5.7e-08 32.6 3.9 1.8e-07 30.9 2.1 2.2 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP59579.1 - 1.9e-05 24.2 0.3 0.00013 21.6 0.1 2.1 1 1 0 2 2 2 1 Beta-lactamase superfamily domain Dabb PF07876.7 OAP59580.1 - 4.5e-13 49.4 0.0 4.9e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain adh_short PF00106.20 OAP59581.1 - 9.2e-12 45.1 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59581.1 - 4.5e-11 42.9 0.0 5.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59581.1 - 2.2e-05 24.2 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP59581.1 - 0.015 14.2 0.1 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 OAP59581.1 - 0.12 12.2 0.3 0.38 10.5 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 OAP59583.1 - 1.4e-13 50.6 0.0 2.4e-13 49.8 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP59583.1 - 8.9e-11 42.1 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP59583.1 - 2.7e-06 26.9 0.3 0.00097 18.6 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 OAP59583.1 - 0.0011 18.0 0.1 0.0015 17.6 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 OAP59583.1 - 0.0019 18.5 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 OAP59583.1 - 0.0043 16.9 0.2 0.0068 16.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 OAP59583.1 - 0.0063 15.4 0.1 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 OAP59583.1 - 0.0083 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 OAP59583.1 - 0.033 14.1 0.1 0.073 12.9 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 OAP59584.1 - 1e-25 90.5 0.0 1.5e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59584.1 - 9.3e-13 48.4 0.0 1.2e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59584.1 - 5.5e-07 29.4 0.0 8.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP59584.1 - 5.5e-05 23.2 0.1 0.00021 21.3 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 OAP59584.1 - 6.3e-05 22.2 0.0 8.5e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 OAP59584.1 - 0.038 14.4 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 OAP59584.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 OAP59584.1 - 0.13 11.7 0.2 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Transp_cyt_pur PF02133.10 OAP59585.1 - 2.5e-82 276.8 44.7 3.8e-75 253.1 26.2 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Fic PF02661.13 OAP59586.1 - 0.052 14.2 0.7 40 5.0 0.1 3.8 3 1 0 3 3 3 0 Fic/DOC family PhyH PF05721.8 OAP59586.1 - 0.055 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 OAP59587.1 - 7.8e-15 54.4 0.1 1.3e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 OAP59588.1 - 8e-66 222.4 31.1 1.3e-54 185.4 13.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP59588.1 - 8.8e-26 90.4 24.3 8.8e-26 90.4 16.8 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF791 PF05631.9 OAP59588.1 - 0.00059 18.6 6.7 0.0037 15.9 0.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF791) MFS_3 PF05977.8 OAP59588.1 - 0.096 10.7 2.5 1.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.19 OAP59589.1 - 7.2e-76 255.5 20.9 8.1e-76 255.4 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59589.1 - 3.5e-21 75.3 23.2 3.5e-21 75.3 16.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-Mss51 PF13824.1 OAP59591.1 - 2.5e-28 97.7 5.2 5.2e-28 96.6 3.6 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 OAP59591.1 - 0.00041 20.1 0.2 0.001 18.9 0.2 1.6 1 0 0 1 1 1 1 MYND finger DIM PF08194.7 OAP59592.1 - 0.15 12.0 0.9 0.52 10.2 0.7 1.9 1 0 0 1 1 1 0 DIM protein Laminin_G_3 PF13385.1 OAP59592.1 - 0.54 10.4 12.3 0.52 10.5 7.6 1.9 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily NDUF_B8 PF05821.6 OAP59593.1 - 1.7e-08 34.3 0.0 2.5e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 OAP59594.1 - 2.7e-73 246.3 0.4 5.4e-73 245.4 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP59594.1 - 1.7e-15 56.6 0.1 9.2e-15 54.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP59594.1 - 2.1e-07 30.6 0.0 6e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 OAP59594.1 - 4.8e-06 26.2 13.7 2.4e-05 24.0 9.5 2.3 1 0 0 1 1 1 1 HSA Sugar_tr PF00083.19 OAP59595.1 - 3e-87 293.0 20.0 3.9e-87 292.7 13.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59595.1 - 9.1e-12 44.3 43.2 7.7e-07 28.1 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Grp1_Fun34_YaaH PF01184.14 OAP59596.1 - 2.1e-30 105.6 14.3 2.7e-30 105.2 9.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MARVEL PF01284.18 OAP59597.1 - 8.8e-09 35.3 6.5 2.9e-08 33.6 4.5 1.8 1 1 1 2 2 2 1 Membrane-associating domain DUF373 PF04123.8 OAP59597.1 - 0.031 13.3 0.6 0.053 12.5 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Oxidored_q2 PF00420.19 OAP59597.1 - 0.094 12.3 0.3 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L EmrE PF13536.1 OAP59597.1 - 2.1 8.5 5.9 1.9 8.6 1.0 2.3 1 1 0 2 2 2 0 Multidrug resistance efflux transporter APH PF01636.18 OAP59598.1 - 2.4e-05 24.1 0.0 0.00013 21.7 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4135 PF13575.1 OAP59598.1 - 0.023 13.6 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Choline_kinase PF01633.15 OAP59598.1 - 0.027 14.0 0.1 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1937 PF09152.5 OAP59598.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) DUF3208 PF11482.3 OAP59599.1 - 0.12 12.4 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) Ank_2 PF12796.2 OAP59600.1 - 2.1e-83 274.7 12.2 1.1e-12 48.1 0.1 10.0 3 1 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP59600.1 - 2.8e-67 221.2 28.8 2.2e-10 40.4 0.1 14.3 8 3 7 15 15 15 13 Ankyrin repeats (many copies) Ank PF00023.25 OAP59600.1 - 2.8e-63 206.7 37.3 1.3e-07 31.0 0.9 19.1 19 1 0 19 19 19 15 Ankyrin repeat Ank_4 PF13637.1 OAP59600.1 - 1.4e-62 206.9 16.8 2.5e-06 27.8 0.1 13.6 7 4 4 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP59600.1 - 7.4e-49 158.8 13.3 0.0005 20.0 0.0 17.7 18 0 0 18 18 18 10 Ankyrin repeat HET PF06985.6 OAP59600.1 - 3.3e-22 79.1 0.0 8.3e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SchA_CurD PF04486.7 OAP59600.1 - 0.0022 17.8 1.4 5.4 6.8 0.0 4.4 3 1 1 4 4 4 1 SchA/CurD like domain Peptidase_C97 PF05903.9 OAP59601.1 - 2.3e-07 30.6 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 OAP59601.1 - 0.018 15.0 1.2 0.15 12.0 0.8 2.3 1 1 0 1 1 1 0 Lecithin retinol acyltransferase GrpE PF01025.14 OAP59601.1 - 0.065 12.7 1.9 0.091 12.3 0.0 2.0 2 0 0 2 2 2 0 GrpE Macoilin PF09726.4 OAP59602.1 - 0.022 13.0 6.9 0.028 12.7 4.8 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4192 PF13830.1 OAP59602.1 - 0.12 12.0 7.7 0.22 11.1 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) Bacteriocin_IIc PF10439.4 OAP59602.1 - 0.57 10.3 19.3 0.13 12.3 6.4 2.3 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 OAP59602.1 - 5 6.8 27.3 2.9e+02 1.2 18.7 2.4 1 1 1 2 2 2 0 Glycine zipper eIF-3_zeta PF05091.7 OAP59602.1 - 5.1 5.6 20.7 11 4.4 14.4 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BAF1_ABF1 PF04684.8 OAP59602.1 - 6.1 5.5 25.0 8.9 5.0 17.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AMP-binding PF00501.23 OAP59604.1 - 8.6e-76 254.9 0.0 5.1e-75 252.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAP59604.1 - 6.3e-70 234.9 0.0 1e-69 234.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAP59604.1 - 3.8e-11 42.8 0.0 8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 OAP59604.1 - 2.4e-10 41.1 0.0 7.9e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 OAP59604.1 - 7.1e-09 34.7 0.0 3.5e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 OAP59604.1 - 1.1e-08 35.2 0.0 2.2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.15 OAP59604.1 - 0.00015 20.7 0.1 0.00028 19.8 0.1 1.4 1 0 0 1 1 1 1 Condensation domain NAD_binding_10 PF13460.1 OAP59604.1 - 0.0037 17.3 0.0 0.35 10.8 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAP59604.1 - 0.0078 15.1 0.0 0.075 11.9 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Pyr_redox_3 PF13738.1 OAP59605.1 - 4.6e-21 75.8 0.0 1.3e-20 74.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP59605.1 - 1.5e-11 43.2 0.1 1.4e-09 36.7 0.0 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP59605.1 - 6.7e-08 31.8 0.0 0.0002 20.4 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP59605.1 - 1.8e-07 31.0 0.0 6.4e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 OAP59605.1 - 6.5e-06 26.2 0.0 0.15 12.1 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 OAP59605.1 - 0.00091 19.1 0.0 0.011 15.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP59605.1 - 0.0018 17.3 0.0 0.096 11.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAP59605.1 - 0.018 13.9 0.0 0.18 10.6 0.0 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 OAP59605.1 - 0.026 13.4 0.7 0.49 9.2 0.1 2.7 2 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP59605.1 - 0.076 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 OAP59605.1 - 0.11 12.3 0.1 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 ThiF family adh_short PF00106.20 OAP59606.1 - 3.4e-23 82.3 0.0 6.2e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59606.1 - 1.4e-06 28.1 0.0 9.1e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAP59606.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP59606.1 - 0.00082 18.8 0.0 0.0015 17.9 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.1 OAP59606.1 - 0.0012 18.9 0.1 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 OAP59606.1 - 0.013 14.4 0.1 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 OAP59606.1 - 0.046 12.4 0.0 0.081 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 OAP59606.1 - 0.051 13.5 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 OAP59606.1 - 0.075 13.1 0.1 0.16 12.0 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 OAP59607.1 - 1.9e-11 43.3 0.0 3.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59607.1 - 1.6e-05 24.6 12.0 3.6e-05 23.5 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 OAP59608.1 - 4.2e-17 62.5 0.2 1.2e-16 61.0 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59608.1 - 1.1e-13 51.5 0.0 2e-13 50.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59608.1 - 5.6e-05 22.8 0.1 0.0012 18.5 0.1 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP59608.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding Exotox-A_bind PF09101.5 OAP59608.1 - 0.04 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A binding Eno-Rase_NADH_b PF12242.3 OAP59608.1 - 0.12 12.1 0.4 0.28 10.9 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 OAP59608.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 4HBT PF03061.17 OAP59609.1 - 1.4e-08 34.7 0.8 2.3e-08 34.0 0.5 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 OAP59609.1 - 5.6e-06 26.2 0.0 6.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF726 PF05277.7 OAP59613.1 - 2.4e-115 385.1 2.1 2.4e-115 385.1 1.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 OAP59613.1 - 0.0041 17.0 0.6 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Aha1_N PF09229.6 OAP59614.1 - 2.3e-37 127.8 0.1 3.6e-37 127.2 0.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 OAP59614.1 - 2.6e-17 63.0 0.8 4.5e-17 62.3 0.5 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Med3 PF11593.3 OAP59614.1 - 7.9 5.6 5.8 11 5.0 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MRG PF05712.8 OAP59615.1 - 1.1e-35 122.2 0.0 6.4e-34 116.5 0.0 2.3 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.3 OAP59615.1 - 5.1e-05 22.8 0.8 5.1e-05 22.8 0.5 2.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.5 OAP59616.1 - 3.8e-12 45.6 0.1 7.3e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein RNA_pol_3_Rpc31 PF11705.3 OAP59616.1 - 0.038 13.9 1.4 0.065 13.1 1.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.1 OAP59616.1 - 0.094 13.0 2.7 0.2 11.9 1.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4446 PF14584.1 OAP59616.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FBPase PF00316.15 OAP59617.1 - 1.7e-120 401.7 0.0 1.9e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Sugar_tr PF00083.19 OAP59618.1 - 1.2e-91 307.5 27.4 1.5e-91 307.2 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59618.1 - 3.4e-19 68.7 63.0 2.8e-18 65.7 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.6 OAP59618.1 - 4.2 6.6 5.8 6.9 5.9 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) 6PF2K PF01591.13 OAP59620.1 - 2.8e-74 248.9 0.6 4.6e-74 248.2 0.4 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 OAP59620.1 - 1.8e-33 115.8 0.0 4.1e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.5 OAP59620.1 - 6e-06 25.6 0.1 1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAP59620.1 - 1.7e-05 24.7 0.0 6.1e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAP59620.1 - 0.045 14.5 0.2 0.23 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Aa_trans PF01490.13 OAP59621.1 - 6.1e-34 117.1 25.9 6.1e-34 117.1 17.9 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Mit_KHE1 PF10173.4 OAP59622.1 - 0.02 14.7 0.9 0.025 14.4 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF4163 PF13739.1 OAP59622.1 - 0.079 13.7 1.3 0.13 13.0 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) Sds3 PF08598.6 OAP59622.1 - 0.26 10.7 4.9 0.38 10.2 3.4 1.2 1 0 0 1 1 1 0 Sds3-like Remorin_C PF03763.8 OAP59622.1 - 0.29 10.6 8.9 0.42 10.1 6.1 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region DUF3987 PF13148.1 OAP59622.1 - 1.1 7.7 6.1 1.5 7.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) V-SNARE_C PF12352.3 OAP59624.1 - 6.1e-14 51.8 0.1 3e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 OAP59624.1 - 0.0015 18.2 0.1 0.0046 16.6 0.0 1.8 2 0 0 2 2 2 1 Sec20 CHDCT2 PF08074.6 OAP59624.1 - 0.03 14.0 1.0 4.4 7.0 0.8 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain DUF4047 PF13256.1 OAP59624.1 - 0.046 13.6 0.1 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Sigma70_r4 PF04545.11 OAP59624.1 - 0.053 12.8 0.1 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3160 PF11369.3 OAP59624.1 - 0.066 11.5 0.7 0.091 11.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) KxDL PF10241.4 OAP59624.1 - 0.18 11.7 3.1 0.71 9.8 1.0 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein TPR_MLP1_2 PF07926.7 OAP59624.1 - 0.18 11.5 7.9 0.18 11.5 4.4 1.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 OAP59624.1 - 0.48 10.2 2.6 0.8 9.5 1.1 1.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.9 OAP59624.1 - 2.4 8.0 8.0 3.4 7.5 5.6 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.7 OAP59624.1 - 3 6.1 4.9 4.2 5.6 3.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pyr_redox_3 PF13738.1 OAP59625.1 - 6.1e-28 98.2 0.0 1.6e-27 96.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP59625.1 - 4.2e-19 68.1 0.2 4.4e-18 64.7 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like GYF PF02213.11 OAP59625.1 - 7.7e-16 57.4 0.1 1.5e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 GYF domain K_oxygenase PF13434.1 OAP59625.1 - 9.5e-11 41.1 0.4 2.9e-08 33.0 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP59625.1 - 6.5e-10 39.2 0.0 1.5e-08 34.7 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP59625.1 - 2.2e-07 30.7 0.0 7.2e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP59625.1 - 2.4e-05 23.4 0.0 0.00018 20.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP59625.1 - 0.0019 17.9 0.2 0.043 13.5 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 OAP59625.1 - 0.011 15.8 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 OAP59625.1 - 0.018 14.1 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DUF917 PF06032.7 OAP59626.1 - 3.2e-104 348.2 1.2 6.4e-104 347.2 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 OAP59626.1 - 5.2e-43 147.2 1.4 4.4e-40 137.6 0.1 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 OAP59626.1 - 2.9e-32 111.5 0.1 5.2e-31 107.4 0.0 2.6 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 OAP59626.1 - 0.025 13.8 3.7 0.095 11.9 0.3 3.0 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 OAP59626.1 - 0.17 10.8 2.5 9.2 5.1 0.0 2.9 3 0 0 3 3 3 0 StbA protein DIOX_N PF14226.1 OAP59627.1 - 5.8e-27 94.5 0.0 9e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP59627.1 - 2.5e-20 72.6 0.0 4.5e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 OAP59628.1 - 2.4e-90 303.2 36.3 2.4e-90 303.2 25.2 1.5 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aldo_ket_red PF00248.16 OAP59629.1 - 3e-51 173.9 0.0 3.5e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 OAP59630.1 - 7.7e-28 97.0 0.3 1.2e-27 96.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1989 PF09347.5 OAP59631.1 - 1.9e-51 173.8 0.1 3.7e-51 172.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.16 OAP59631.1 - 1.8e-18 66.3 0.0 3.4e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 OAP59631.1 - 0.00037 19.9 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 OAP59631.1 - 0.15 10.0 0.0 0.22 9.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) GAGA_bind PF06217.7 OAP59632.1 - 0.00018 21.5 7.4 0.00018 21.5 5.1 3.9 1 1 2 4 4 4 1 GAGA binding protein-like family Myosin_tail_1 PF01576.14 OAP59632.1 - 0.0014 16.5 93.4 0.25 8.9 4.6 4.2 2 2 2 4 4 4 4 Myosin tail CENP-F_leu_zip PF10473.4 OAP59632.1 - 0.0036 17.1 13.7 0.0036 17.1 9.5 6.3 2 2 2 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 OAP59632.1 - 0.95 8.6 88.4 0.074 12.2 18.2 6.3 1 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding Sec20 PF03908.8 OAP59632.1 - 1.5 8.5 14.6 2.5 7.8 0.3 4.4 2 2 1 3 3 3 0 Sec20 WEMBL PF05701.6 OAP59632.1 - 4.3 5.6 100.4 0.013 13.9 14.6 3.4 1 1 3 4 4 4 0 Weak chloroplast movement under blue light HAD_2 PF13419.1 OAP59633.1 - 1.7e-15 57.7 0.1 3.9e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Isochorismatase PF00857.15 OAP59634.1 - 5.6e-37 127.3 0.0 1.5e-36 125.9 0.0 1.8 1 0 0 1 1 1 1 Isochorismatase family UPF0239 PF06783.6 OAP59635.1 - 0.082 12.8 2.9 0.33 10.8 2.0 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Zip PF02535.17 OAP59636.1 - 8 5.3 11.2 3.8 6.4 1.0 3.0 3 0 0 3 3 3 0 ZIP Zinc transporter TauD PF02668.11 OAP59639.1 - 7.5e-51 173.2 0.1 8.8e-51 173.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1479 PF07350.7 OAP59639.1 - 0.017 13.5 0.2 0.034 12.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) P16-Arc PF04699.9 OAP59640.1 - 3.8e-53 179.6 0.0 4.4e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Dynactin_p62 PF05502.8 OAP59641.1 - 2.5e-127 425.5 0.1 3.1e-127 425.3 0.1 1.1 1 0 0 1 1 1 1 Dynactin p62 family Methyltransf_23 PF13489.1 OAP59642.1 - 7.2e-11 42.0 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP59642.1 - 2.4e-09 37.5 0.0 5.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP59642.1 - 4.9e-06 26.2 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP59642.1 - 5.9e-06 26.6 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP59642.1 - 0.011 16.0 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 OAP59642.1 - 0.053 12.6 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_S7e PF01251.13 OAP59643.1 - 1.3e-79 266.1 0.1 1.4e-79 265.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_zinc_N PF00107.21 OAP59644.1 - 9.1e-27 93.1 1.0 9.1e-27 93.1 0.7 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP59644.1 - 1e-10 41.3 0.3 2.7e-10 39.9 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP59644.1 - 5.7e-06 27.2 0.0 0.0026 18.6 0.0 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP59644.1 - 0.0001 21.9 0.6 0.00018 21.0 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 OAP59644.1 - 0.00021 21.2 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain GST_N_3 PF13417.1 OAP59645.1 - 2.3e-10 40.5 0.0 4.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP59645.1 - 4e-07 29.9 0.0 7.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP59645.1 - 3.7e-06 26.7 0.0 8.6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAP59645.1 - 8.5e-05 22.4 0.1 0.00018 21.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP59645.1 - 0.005 17.3 0.0 0.011 16.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAP59645.1 - 0.067 13.3 0.0 0.34 11.1 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain zf-RING_2 PF13639.1 OAP59648.1 - 9.8e-14 50.9 5.7 1.6e-13 50.2 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 OAP59648.1 - 5.4e-12 45.3 0.0 3e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 PA domain zf-rbx1 PF12678.2 OAP59648.1 - 1.1e-08 35.0 1.6 2e-08 34.1 1.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 OAP59648.1 - 1.4e-08 34.6 5.2 2.2e-08 33.9 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP59648.1 - 4.5e-08 32.6 3.0 7.1e-08 31.9 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP59648.1 - 5.3e-08 32.4 2.3 8.2e-08 31.8 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAP59648.1 - 5.6e-08 32.3 3.0 8.3e-08 31.7 2.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAP59648.1 - 0.0021 17.8 0.7 0.0042 16.8 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 OAP59648.1 - 0.084 12.7 3.1 0.26 11.2 2.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAP59648.1 - 0.089 12.5 2.7 0.21 11.3 1.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 OAP59648.1 - 0.11 12.5 2.4 0.3 11.0 1.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 OAP59648.1 - 0.12 12.3 3.4 0.23 11.5 2.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 OAP59648.1 - 0.13 11.8 2.6 0.24 11.0 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ABA_GPCR PF12430.3 OAP59648.1 - 0.23 10.5 0.3 0.42 9.7 0.2 1.3 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor PHD PF00628.24 OAP59648.1 - 0.75 9.5 3.2 1.3 8.7 2.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 OAP59648.1 - 1.9 8.5 3.6 3.5 7.7 2.5 1.4 1 0 0 1 1 1 0 RING-like domain MIP PF00230.15 OAP59649.1 - 3.7e-50 170.4 11.3 5.4e-50 169.9 7.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein PRP21_like_P PF12230.3 OAP59650.1 - 1.1e-56 191.9 5.3 1.7e-55 188.0 3.7 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 OAP59650.1 - 2e-36 123.3 0.7 4.9e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 Surp module PMT PF02366.13 OAP59651.1 - 2.3e-76 256.4 15.3 4.1e-76 255.5 10.6 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAP59651.1 - 1e-54 185.0 0.1 1.5e-54 184.4 0.1 1.3 1 0 0 1 1 1 1 MIR domain EB1 PF03271.12 OAP59652.1 - 7.4e-17 61.1 0.1 1.4e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 OAP59652.1 - 6.8e-08 32.5 0.8 1.8e-07 31.1 0.4 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain Syja_N PF02383.13 OAP59652.1 - 0.1 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Whi5 PF08528.6 OAP59654.1 - 8.6e-09 34.7 0.7 1.5e-08 33.9 0.5 1.4 1 0 0 1 1 1 1 Whi5 like Peptidase_C15 PF01470.12 OAP59657.1 - 1.7e-11 44.3 0.0 2.9e-08 33.8 0.0 3.1 2 1 0 2 2 2 2 Pyroglutamyl peptidase Mad3_BUB1_I PF08311.7 OAP59658.1 - 3e-42 143.3 0.0 4.9e-42 142.6 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 OAP59658.1 - 1.5e-10 40.6 0.0 4.8e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 OAP59658.1 - 5e-06 26.3 0.0 1.6e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 OAP59658.1 - 0.0046 16.0 0.0 0.024 13.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase SAYSvFN PF10260.4 OAP59659.1 - 0.056 13.2 0.6 0.24 11.1 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) 7TMR-DISM_7TM PF07695.6 OAP59659.1 - 0.062 12.9 5.2 0.09 12.4 3.6 1.3 1 1 0 1 1 1 0 7TM diverse intracellular signalling Ribosomal_S4e PF00900.15 OAP59660.1 - 7.6e-32 108.8 0.5 1.8e-31 107.6 0.3 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 OAP59660.1 - 7.4e-17 60.9 4.8 1.3e-16 60.0 3.3 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 OAP59660.1 - 0.0002 20.9 1.4 0.0002 20.9 1.0 2.8 3 0 0 3 3 3 1 KOW motif S4 PF01479.20 OAP59660.1 - 0.032 13.6 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 S4 domain Semialdhyde_dhC PF02774.13 OAP59661.1 - 7.4e-36 123.7 0.0 9.8e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 OAP59661.1 - 1.6e-28 99.4 0.0 5.3e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 OAP59661.1 - 0.018 15.5 0.0 0.054 14.0 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 OAP59661.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2062 PF09835.4 OAP59662.1 - 0.03 13.9 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) p450 PF00067.17 OAP59663.1 - 7.8e-67 225.7 0.2 1e-66 225.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mannosyl_trans2 PF04188.8 OAP59664.1 - 2.5e-39 135.4 9.4 2.9e-39 135.2 6.5 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF4064 PF13273.1 OAP59664.1 - 0.033 14.2 1.7 0.033 14.2 1.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF2206 PF09971.4 OAP59664.1 - 7.8 5.2 8.1 0.63 8.8 2.4 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) p450 PF00067.17 OAP59665.1 - 1.6e-62 211.5 0.0 2.1e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.13 OAP59666.1 - 6.6e-55 185.9 0.0 9e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family EPTP PF03736.12 OAP59667.1 - 2.2e-34 116.8 6.2 1.4e-06 27.9 0.4 8.3 7 1 0 7 7 7 6 EPTP domain Abhydrolase_6 PF12697.2 OAP59667.1 - 5.5e-32 111.4 0.0 1.1e-31 110.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP59667.1 - 5.5e-16 58.8 0.0 8.8e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP59667.1 - 1.3e-11 44.3 0.0 3.3e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 OAP59667.1 - 2.7e-05 22.7 0.0 4.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Velvet PF11754.3 OAP59669.1 - 6.3e-27 94.4 1.6 3.9e-25 88.6 1.1 2.3 1 1 0 1 1 1 1 Velvet factor GFA PF04828.9 OAP59670.1 - 1.1e-21 76.5 8.4 9e-12 44.7 0.1 3.1 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 OAP59670.1 - 0.12 12.1 3.0 3.9 7.3 0.3 2.7 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_S27 PF01599.14 OAP59670.1 - 0.19 11.5 3.8 2.3 8.1 0.3 2.9 2 0 0 2 2 2 0 Ribosomal protein S27a Zn_ribbon_recom PF13408.1 OAP59670.1 - 0.2 11.9 7.9 0.5 10.6 0.1 3.4 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.1 OAP59670.1 - 3.1 7.1 8.9 11 5.3 0.6 3.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 OAP59670.1 - 5 6.7 17.0 2 7.9 0.1 3.7 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Sugar_tr PF00083.19 OAP59671.1 - 4.4e-77 259.5 23.1 5.2e-77 259.3 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59671.1 - 6.6e-29 100.7 50.1 8.2e-28 97.1 18.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 OAP59672.1 - 0.00022 21.3 0.0 0.0022 18.0 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_3 PF01494.14 OAP59673.1 - 8e-10 38.3 0.1 3.3e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DUF2407_C PF13373.1 OAP59674.1 - 9.1e-41 139.0 0.0 1.4e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 OAP59674.1 - 9.7e-25 86.5 0.0 2.1e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 OAP59674.1 - 0.00047 19.4 0.0 0.00091 18.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family V-SNARE PF05008.10 OAP59675.1 - 3.4e-22 78.4 3.9 3.4e-22 78.4 2.7 1.9 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 OAP59675.1 - 1.3e-18 66.7 5.4 1.3e-18 66.7 3.7 2.8 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 OAP59675.1 - 0.00019 21.0 2.3 0.00035 20.2 0.1 2.2 2 0 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 OAP59675.1 - 0.023 12.8 1.7 0.03 12.4 0.2 1.8 2 0 0 2 2 2 0 Fusion glycoprotein F0 DUF4407 PF14362.1 OAP59675.1 - 0.048 12.6 7.3 0.066 12.1 5.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TBCA PF02970.11 OAP59675.1 - 0.1 12.6 5.5 0.64 10.1 0.1 2.8 2 1 1 3 3 3 0 Tubulin binding cofactor A Synaptobrevin PF00957.16 OAP59675.1 - 2.1 8.0 4.7 0.44 10.1 0.1 2.2 3 0 0 3 3 3 0 Synaptobrevin Amino_oxidase PF01593.19 OAP59676.1 - 2.3e-12 46.7 0.0 9.5e-12 44.7 0.0 1.9 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP59676.1 - 5.7e-12 45.4 0.1 1.1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP59676.1 - 4.5e-09 36.2 0.3 0.0031 17.3 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 OAP59676.1 - 9.2e-06 24.7 1.2 0.00013 20.9 0.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP59676.1 - 3.3e-05 24.0 0.8 0.025 14.6 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP59676.1 - 0.03 14.1 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP59676.1 - 0.11 12.8 0.1 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATP_bind_3 PF01171.15 OAP59677.1 - 6.6e-20 71.3 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 OAP59677.1 - 0.00027 21.2 0.0 0.00058 20.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 OAP59677.1 - 0.00091 18.6 0.6 0.00091 18.6 0.4 3.2 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.11 OAP59677.1 - 0.028 12.9 0.0 0.049 12.1 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.15 OAP59677.1 - 1.8 8.3 7.3 3 7.6 0.6 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) UPF0547 PF10571.4 OAP59677.1 - 7.2 6.4 9.1 4 7.2 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 AAA PF00004.24 OAP59678.1 - 1.2e-37 129.0 0.0 6.8e-37 126.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP59678.1 - 5.5e-05 23.3 0.5 0.0074 16.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 OAP59678.1 - 0.00022 21.2 2.2 0.041 13.8 0.0 3.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 OAP59678.1 - 0.00085 20.1 0.0 0.0039 18.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 OAP59678.1 - 0.0026 17.6 0.0 0.011 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP59678.1 - 0.0029 17.3 0.5 0.016 14.9 0.2 2.3 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 OAP59678.1 - 0.0034 16.4 0.0 0.0068 15.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 OAP59678.1 - 0.0062 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 OAP59678.1 - 0.012 15.0 2.5 4 6.7 0.2 3.4 2 1 1 3 3 3 0 AAA domain ox_reductase_C PF08635.5 OAP59678.1 - 0.021 14.2 0.1 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal AAA_14 PF13173.1 OAP59678.1 - 0.022 14.6 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAP59678.1 - 0.039 14.2 0.1 0.23 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 OAP59678.1 - 0.042 13.5 0.2 0.13 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 OAP59678.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 OAP59678.1 - 0.051 13.1 2.1 0.14 11.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain Sigma54_activ_2 PF14532.1 OAP59678.1 - 0.06 13.3 0.2 0.22 11.5 0.0 2.0 2 0 0 2 2 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 OAP59678.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 OAP59678.1 - 0.065 12.3 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 OAP59678.1 - 0.16 10.6 0.1 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_17 PF13207.1 OAP59679.1 - 2.8e-06 28.1 0.0 5.1e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP59679.1 - 0.00027 21.2 0.0 0.00081 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 OAP59679.1 - 0.0061 16.1 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 OAP59679.1 - 0.035 14.0 0.2 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 OAP59679.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 OAP59679.1 - 0.083 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein LIM_bind PF01803.11 OAP59680.1 - 4.2e-52 176.6 0.0 4.2e-52 176.6 0.0 3.5 2 1 1 3 3 3 1 LIM-domain binding protein TIP49 PF06068.8 OAP59681.1 - 4.5e-184 611.7 0.0 5.3e-184 611.5 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 OAP59681.1 - 1.4e-10 41.5 0.1 6.2e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAP59681.1 - 2.5e-10 39.8 0.8 1.7e-06 27.2 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAP59681.1 - 1.1e-06 28.8 0.0 0.00025 21.0 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 OAP59681.1 - 2.5e-05 24.4 0.1 0.088 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 OAP59681.1 - 5.4e-05 22.8 0.1 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 OAP59681.1 - 0.00023 21.1 0.1 0.00082 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAP59681.1 - 0.00098 18.8 0.1 0.15 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 OAP59681.1 - 0.001 18.1 0.2 0.0022 17.0 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 OAP59681.1 - 0.0013 18.2 0.1 0.7 9.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 OAP59681.1 - 0.0036 16.7 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAP59681.1 - 0.018 14.2 0.1 0.57 9.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 OAP59681.1 - 0.019 14.8 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 OAP59681.1 - 0.025 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 OAP59681.1 - 0.029 13.4 0.2 0.074 12.1 0.0 1.8 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 OAP59681.1 - 0.03 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 OAP59681.1 - 0.047 13.9 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 OAP59681.1 - 0.048 14.4 0.0 0.13 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 OAP59681.1 - 0.063 13.3 0.0 3.7 7.5 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Ribosomal_L28 PF00830.14 OAP59682.1 - 1.8e-12 46.8 0.3 3.8e-12 45.8 0.2 1.6 1 0 0 1 1 1 1 Ribosomal L28 family DSBA PF01323.15 OAP59683.1 - 2.5e-27 95.7 0.0 3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain SNF2_N PF00176.18 OAP59684.1 - 5.5e-37 127.1 0.1 2.8e-33 114.9 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP59684.1 - 0.0094 15.7 0.0 0.028 14.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP59684.1 - 0.025 14.3 0.0 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Ald_Xan_dh_C2 PF02738.13 OAP59685.1 - 1.2e-195 650.9 0.1 1.7e-195 650.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 OAP59685.1 - 7.4e-47 158.9 0.0 1.3e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 OAP59685.1 - 1.6e-30 105.0 0.2 1.5e-29 101.9 0.0 2.8 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 OAP59685.1 - 1.1e-27 95.6 0.0 2.5e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 OAP59685.1 - 1.8e-27 95.6 0.0 4.7e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 OAP59685.1 - 2.1e-08 33.8 0.1 2.1e-08 33.8 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain KH_1 PF00013.24 OAP59687.1 - 1.5e-33 114.2 8.4 5.7e-12 45.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 OAP59687.1 - 4.1e-25 86.9 13.3 1.8e-09 37.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 OAP59687.1 - 3.8e-06 26.3 3.1 0.04 13.4 0.0 2.8 3 0 0 3 3 3 2 KH domain KH_4 PF13083.1 OAP59687.1 - 0.0009 18.8 4.6 0.057 13.0 0.0 3.1 3 0 0 3 3 3 2 KH domain dUTPase PF00692.14 OAP59687.1 - 0.036 13.5 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 dUTPase YbaJ PF10757.4 OAP59688.1 - 0.18 11.9 2.0 0.9 9.6 0.3 2.7 2 1 1 3 3 3 0 Biofilm formation regulator YbaJ DUF377 PF04041.8 OAP59689.1 - 3.1e-49 167.3 0.0 6.5e-49 166.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_32N PF00251.15 OAP59689.1 - 2.8e-08 33.4 0.9 4.1e-05 23.0 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 OAP59689.1 - 3.2e-08 32.9 0.9 0.0007 18.7 0.0 3.9 3 1 1 4 4 4 2 Glycosyl hydrolases family 43 DNA_pol_E_B PF04042.11 OAP59689.1 - 0.00094 18.4 0.3 0.0014 17.9 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Nup96 PF12110.3 OAP59690.1 - 4.7e-53 180.1 0.2 6.7e-53 179.6 0.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 OAP59690.1 - 1.6e-46 157.6 0.0 2.9e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 OAP59690.1 - 3.7e-09 36.8 87.8 7.4e-08 32.6 29.5 8.9 3 2 4 7 7 7 3 Nucleoporin FG repeat region Sec16_C PF12931.2 OAP59690.1 - 0.19 11.4 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 GET2 PF08690.5 OAP59691.1 - 0.076 12.2 9.0 0.36 10.0 6.3 2.2 1 1 0 1 1 1 0 GET complex subunit GET2 DUF919 PF06034.6 OAP59691.1 - 0.15 11.7 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) AMP-binding PF00501.23 OAP59692.1 - 8.8e-89 297.7 0.2 1.2e-88 297.3 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP59692.1 - 4.3e-22 78.8 0.1 1.7e-20 73.7 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain IMS PF00817.15 OAP59692.1 - 0.14 11.9 0.0 1.8 8.3 0.0 2.4 2 1 1 3 3 3 0 impB/mucB/samB family EF-hand_1 PF00036.27 OAP59693.1 - 5.9e-14 50.2 0.1 2e-05 23.5 0.0 3.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 OAP59693.1 - 3.1e-13 48.4 0.4 2e-05 24.1 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 OAP59693.1 - 4.3e-12 45.9 0.6 2.9e-06 27.3 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAP59693.1 - 2.2e-09 36.7 1.0 3.6e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 OAP59693.1 - 0.0041 16.8 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 OAP59693.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 OAP59693.1 - 0.072 12.4 1.1 3.2 7.2 0.3 2.8 3 0 0 3 3 3 0 EF hand IMS PF00817.15 OAP59694.1 - 1.2e-36 125.7 0.0 2e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAP59694.1 - 8e-08 32.2 0.5 2.2e-07 30.8 0.2 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 OAP59694.1 - 1.6e-06 27.7 0.7 4.1e-05 23.3 0.0 3.1 3 0 0 3 3 3 1 IMS family HHH motif HHH PF00633.18 OAP59694.1 - 0.024 14.3 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.1 OAP59694.1 - 0.041 14.0 0.0 0.56 10.4 0.0 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix domain HHH_8 PF14716.1 OAP59694.1 - 0.051 13.7 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain Amidohydro_4 PF13147.1 OAP59696.1 - 4.5e-12 46.5 1.6 7.6e-11 42.5 1.1 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 OAP59696.1 - 8.3e-07 28.9 0.0 1.6e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 OAP59696.1 - 5.2e-06 25.9 0.0 1.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 OAP59696.1 - 2.2e-05 24.1 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase C2 PF00168.25 OAP59697.1 - 7.7e-20 70.5 0.0 6.7e-15 54.7 0.0 3.0 3 0 0 3 3 3 2 C2 domain Reprolysin_5 PF13688.1 OAP59698.1 - 3.7e-60 203.2 11.7 3.7e-60 203.2 8.1 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 OAP59698.1 - 4.5e-49 166.7 4.7 1e-48 165.6 3.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAP59698.1 - 3.1e-47 160.8 6.0 8.1e-47 159.5 3.6 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAP59698.1 - 1.1e-20 74.4 0.6 1.1e-20 74.4 0.4 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 OAP59698.1 - 2.7e-17 62.7 33.0 2.7e-17 62.7 22.9 4.7 2 2 1 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 OAP59698.1 - 0.00041 20.1 0.1 0.00087 19.0 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 OAP59698.1 - 0.0022 17.5 10.3 0.0022 17.5 7.1 3.5 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Aminotran_1_2 PF00155.16 OAP59699.1 - 2.9e-54 184.4 0.0 3.6e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAP59699.1 - 0.0019 16.5 0.0 0.0029 15.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 OAP59699.1 - 0.0042 16.2 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase MTD PF01993.13 OAP59699.1 - 0.031 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Aminotran_5 PF00266.14 OAP59699.1 - 0.15 10.7 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V MgsA_C PF12002.3 OAP59700.1 - 6.6e-61 204.8 0.2 1.8e-60 203.4 0.0 1.8 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 OAP59700.1 - 1.4e-13 51.1 0.1 4e-13 49.7 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAP59700.1 - 2.2e-10 39.9 0.0 7.3e-10 38.2 0.0 1.6 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 OAP59700.1 - 2.8e-05 23.8 0.0 0.00037 20.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAP59700.1 - 4e-05 22.8 0.2 0.14 11.2 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 OAP59700.1 - 0.0002 20.9 0.1 0.012 15.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 OAP59700.1 - 0.0004 20.0 0.3 0.002 17.8 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 OAP59700.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAP59700.1 - 0.0017 18.4 0.7 0.014 15.5 0.5 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 OAP59700.1 - 0.0018 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 OAP59700.1 - 0.0018 17.8 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 OAP59700.1 - 0.0021 17.9 0.4 2.3 8.0 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_16 PF13191.1 OAP59700.1 - 0.0047 16.9 0.3 0.24 11.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 OAP59700.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 OAP59700.1 - 0.02 15.7 1.0 0.1 13.4 0.0 2.4 2 1 1 3 3 2 0 AAA domain RecO_C PF02565.10 OAP59700.1 - 0.024 14.4 0.0 0.075 12.8 0.0 1.8 1 0 0 1 1 1 0 Recombination protein O C terminal zf-C2HC_2 PF13913.1 OAP59700.1 - 0.04 13.5 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type AAA_30 PF13604.1 OAP59700.1 - 0.068 12.7 0.4 0.23 11.0 0.3 1.8 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 OAP59700.1 - 0.091 11.4 0.0 0.23 10.1 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 OAP59700.1 - 0.097 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-TRAF PF02176.13 OAP59700.1 - 0.13 12.6 0.4 0.24 11.8 0.3 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger NB-ARC PF00931.17 OAP59700.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain LigD_N PF13298.1 OAP59701.1 - 0.036 14.1 1.4 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) Pro_dh PF01619.13 OAP59702.1 - 1.1e-40 139.5 0.1 1.7e-40 138.9 0.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase DAO PF01266.19 OAP59702.1 - 1.2e-33 116.5 0.0 2.2e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP59702.1 - 0.00055 20.0 0.0 0.0017 18.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP59702.1 - 0.011 15.7 0.0 0.041 13.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 OAP59702.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 ThiF family Mito_carr PF00153.22 OAP59703.1 - 7.7e-52 172.9 8.2 1.5e-20 72.7 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 OAP59703.1 - 0.052 13.6 0.9 0.19 11.7 0.1 2.3 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Cupin_2 PF07883.6 OAP59704.1 - 4.8e-08 32.3 0.2 1.3e-06 27.7 0.1 2.3 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 OAP59704.1 - 5.5e-06 25.8 0.0 7.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 OAP59704.1 - 0.054 12.8 0.1 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) P5CR_dimer PF14748.1 OAP59706.1 - 2.8e-19 69.0 0.3 1.6e-18 66.6 0.4 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 OAP59706.1 - 3.1e-15 56.3 0.0 8.3e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 OAP59706.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 OAP59706.1 - 0.02 14.9 0.4 0.034 14.1 0.2 1.5 1 1 0 1 1 1 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 OAP59706.1 - 0.12 12.0 2.8 0.24 11.1 0.6 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DHDPS PF00701.17 OAP59707.1 - 1.9e-12 46.3 0.2 2.2e-09 36.3 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family WTF PF03303.8 OAP59707.1 - 0.087 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 WTF protein Fungal_trans PF04082.13 OAP59708.1 - 4e-21 75.0 0.2 8.5e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 OAP59709.1 - 5.2e-94 315.1 0.0 6.5e-94 314.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP59709.1 - 0.038 12.7 0.0 0.26 9.9 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 OAP59710.1 - 1.2e-136 455.7 0.2 1.4e-136 455.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP59710.1 - 0.0075 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Calreticulin PF00262.13 OAP59711.1 - 5.6e-165 548.4 18.1 7.7e-165 547.9 12.5 1.2 1 0 0 1 1 1 1 Calreticulin family YtxH PF12732.2 OAP59711.1 - 1.9 8.9 6.5 7.6 6.9 4.5 2.0 1 0 0 1 1 1 0 YtxH-like protein Aldolase_II PF00596.16 OAP59712.1 - 1.4e-40 138.8 0.0 1.7e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GCN5L1 PF06320.8 OAP59713.1 - 2.3e-09 37.1 2.1 2.9e-09 36.7 1.4 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF2968 PF11180.3 OAP59713.1 - 0.0011 18.3 2.4 0.0016 17.9 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Tektin PF03148.9 OAP59713.1 - 0.0014 17.2 2.1 0.0016 17.0 1.5 1.2 1 0 0 1 1 1 1 Tektin family ATG16 PF08614.6 OAP59713.1 - 0.0015 18.4 4.8 0.0018 18.1 3.3 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF3450 PF11932.3 OAP59713.1 - 0.012 14.9 3.7 0.015 14.5 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3552 PF12072.3 OAP59713.1 - 0.013 14.6 3.4 0.016 14.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2884 PF11101.3 OAP59713.1 - 0.014 14.7 0.6 0.014 14.7 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Taxilin PF09728.4 OAP59713.1 - 0.017 14.2 5.7 0.15 11.1 1.5 2.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein HAUS6_N PF14661.1 OAP59713.1 - 0.024 13.9 2.1 0.027 13.8 1.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Mt_ATP-synt_B PF05405.9 OAP59713.1 - 0.046 13.1 0.8 0.092 12.2 0.6 1.5 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Tropomyosin_1 PF12718.2 OAP59713.1 - 0.052 13.3 7.3 0.082 12.7 5.1 1.3 1 0 0 1 1 1 0 Tropomyosin like UPF0242 PF06785.6 OAP59713.1 - 0.076 11.6 2.0 0.095 11.3 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 OAP59713.1 - 0.1 11.6 5.5 0.13 11.2 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 OAP59713.1 - 0.1 11.0 4.3 0.12 10.8 3.0 1.0 1 0 0 1 1 1 0 AAA domain IL2 PF00715.12 OAP59713.1 - 0.11 12.2 0.2 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 Interleukin 2 NYD-SP28_assoc PF14775.1 OAP59713.1 - 0.12 12.0 1.4 0.31 10.7 0.7 1.9 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF972 PF06156.8 OAP59713.1 - 0.14 12.5 3.9 0.24 11.7 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) LOH1CR12 PF10158.4 OAP59713.1 - 0.2 11.4 1.2 0.25 11.1 0.8 1.2 1 0 0 1 1 1 0 Tumour suppressor protein IncA PF04156.9 OAP59713.1 - 0.21 11.1 2.0 0.24 10.9 1.4 1.2 1 0 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 OAP59713.1 - 0.21 11.7 5.6 0.66 10.1 3.5 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 OAP59713.1 - 0.22 11.3 6.6 0.12 12.1 1.5 2.2 1 1 0 2 2 2 0 Prefoldin subunit Laminin_II PF06009.7 OAP59713.1 - 0.32 10.7 6.2 0.43 10.3 4.0 1.4 1 1 0 1 1 1 0 Laminin Domain II bZIP_1 PF00170.16 OAP59713.1 - 0.36 10.8 6.0 1.1 9.3 3.3 2.4 1 1 1 2 2 2 0 bZIP transcription factor Reo_sigmaC PF04582.7 OAP59713.1 - 0.41 9.7 3.1 0.49 9.5 2.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 OAP59713.1 - 0.43 10.4 3.4 1.2 8.9 2.4 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.10 OAP59713.1 - 3 7.3 4.9 5.9 6.4 3.2 1.8 1 1 0 1 1 1 0 Septum formation initiator Vps39_1 PF10366.4 OAP59714.1 - 8e-32 109.4 0.0 1.3e-30 105.5 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 OAP59714.1 - 5.4e-30 103.7 0.0 2.1e-29 101.8 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 OAP59714.1 - 8.8e-17 61.4 0.0 1.7e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 OAP59714.1 - 2.6e-07 30.3 3.9 1.4e-06 27.9 0.3 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_11 PF13414.1 OAP59714.1 - 0.00024 20.6 2.8 0.3 10.7 0.0 4.3 4 1 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 OAP59714.1 - 0.041 14.5 6.4 9.6 7.0 0.3 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP59714.1 - 0.044 13.4 0.3 4.3 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Gon7 PF08738.5 OAP59715.1 - 2.4e-15 56.3 8.1 2.3e-14 53.2 5.6 1.9 1 1 0 1 1 1 1 Gon7 family GnsAB PF08178.6 OAP59715.1 - 0.016 14.8 1.2 0.026 14.2 0.8 1.5 1 0 0 1 1 1 0 GnsA/GnsB family DUF4611 PF15387.1 OAP59715.1 - 0.19 11.8 7.0 0.74 9.9 4.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) RP-C_C PF11800.3 OAP59715.1 - 0.29 10.7 3.8 0.32 10.6 2.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region AATF-Che1 PF13339.1 OAP59715.1 - 0.43 10.7 5.2 0.54 10.4 3.6 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4163 PF13739.1 OAP59715.1 - 0.56 11.0 3.7 0.76 10.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) Vfa1 PF08432.5 OAP59715.1 - 3 7.8 10.9 3.4 7.6 7.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HbrB PF08539.6 OAP59716.1 - 1.3e-49 168.0 0.0 2.7e-49 167.0 0.0 1.5 2 0 0 2 2 2 1 HbrB-like Abhydrolase_6 PF12697.2 OAP59717.1 - 4.6e-22 79.0 0.0 5.5e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP59717.1 - 1.5e-10 41.0 0.0 3.6e-05 23.4 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP59717.1 - 1.3e-08 34.6 0.0 3.5e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP59717.1 - 0.00036 19.8 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 OAP59717.1 - 0.00065 19.0 0.1 0.00087 18.6 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 OAP59717.1 - 0.0052 16.6 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 OAP59717.1 - 0.0071 16.2 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein PLDc_2 PF13091.1 OAP59717.1 - 0.047 13.4 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain DUF3425 PF11905.3 OAP59718.1 - 5.6e-23 81.3 0.2 9.9e-23 80.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP59718.1 - 7e-05 22.7 5.4 0.00012 21.9 3.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP59718.1 - 0.0032 17.2 5.0 0.0052 16.5 3.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF2275 PF10039.4 OAP59719.1 - 0.11 12.3 0.8 0.33 10.8 0.3 2.0 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) Trp_oprn_chp PF09534.5 OAP59719.1 - 0.15 11.6 4.4 0.035 13.7 0.8 1.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) VSP PF03302.8 OAP59719.1 - 5.2 5.6 8.3 0.076 11.6 0.7 1.5 2 0 0 2 2 2 0 Giardia variant-specific surface protein Abhydrolase_3 PF07859.8 OAP59720.1 - 2.9e-36 125.0 0.0 5.7e-26 91.4 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 OAP59720.1 - 0.062 11.9 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Fis1_TPR_C PF14853.1 OAP59721.1 - 1.8e-25 88.5 1.8 2.8e-25 87.9 1.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 OAP59721.1 - 3.4e-17 61.4 0.0 5.5e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 OAP59721.1 - 0.0015 18.3 3.1 0.0015 18.3 2.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP59721.1 - 0.0066 17.0 0.1 0.013 16.1 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAP59721.1 - 0.026 14.9 0.3 0.077 13.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP59721.1 - 0.53 9.9 3.6 1.1 8.9 2.5 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 OAP59722.1 - 1.1e-37 128.2 5.3 1.8e-36 124.4 0.3 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 OAP59722.1 - 0.0033 17.3 1.5 0.025 14.5 0.0 2.1 1 1 1 2 2 2 1 Lantibiotic streptin immunity protein V_ATPase_I PF01496.14 OAP59722.1 - 0.0068 14.3 3.7 0.0083 14.0 2.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MAD PF05557.8 OAP59722.1 - 0.0074 14.4 5.4 0.011 13.8 3.7 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Laminin_II PF06009.7 OAP59722.1 - 0.043 13.5 6.7 1 9.1 0.8 2.2 1 1 0 2 2 2 0 Laminin Domain II SYCE1 PF15233.1 OAP59722.1 - 0.055 13.4 0.7 0.055 13.4 0.5 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 LMBR1 PF04791.11 OAP59722.1 - 0.065 11.8 0.8 0.065 11.8 0.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6 PF04111.7 OAP59722.1 - 0.092 11.7 6.2 0.12 11.3 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 OAP59722.1 - 0.11 12.4 1.5 15 5.5 0.3 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin PF00804.20 OAP59722.1 - 0.11 12.6 9.1 0.13 12.4 4.2 2.2 1 1 1 2 2 2 0 Syntaxin PEP-utilisers_N PF05524.8 OAP59722.1 - 0.17 11.6 10.4 0.27 11.0 2.0 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Prefoldin_2 PF01920.15 OAP59722.1 - 0.19 11.5 8.4 0.67 9.7 1.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit Viral_P18 PF04521.8 OAP59722.1 - 0.2 11.1 8.5 0.12 11.8 0.9 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein RPN7 PF10602.4 OAP59722.1 - 0.2 11.0 3.3 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Nsp1_C PF05064.8 OAP59722.1 - 0.39 10.3 4.9 1.7 8.3 0.8 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF3847 PF12958.2 OAP59722.1 - 0.43 10.3 8.1 1.8 8.3 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) GAS PF13851.1 OAP59722.1 - 0.5 9.5 9.1 0.27 10.4 2.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 OAP59722.1 - 0.53 9.7 11.0 0.73 9.3 7.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4613 PF15390.1 OAP59722.1 - 0.54 8.3 3.6 0.63 8.1 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF972 PF06156.8 OAP59722.1 - 0.61 10.4 6.2 0.57 10.5 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 OAP59722.1 - 0.62 9.9 11.9 0.93 9.3 8.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1319 PF07028.6 OAP59722.1 - 0.69 10.1 6.4 2.2 8.4 4.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) DUF4164 PF13747.1 OAP59722.1 - 0.71 10.0 11.1 0.46 10.6 5.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) SlyX PF04102.7 OAP59722.1 - 0.9 9.9 6.1 11 6.4 0.6 2.6 2 1 0 2 2 2 0 SlyX Sec2p PF06428.6 OAP59722.1 - 1.5 8.6 9.4 2.3 8.0 1.7 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Atg14 PF10186.4 OAP59722.1 - 2.1 7.2 8.4 2.9 6.7 5.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 OAP59722.1 - 2.2 7.8 6.5 1.6 8.2 1.9 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 OAP59722.1 - 2.2 8.7 11.0 8.7 6.8 1.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 OAP59722.1 - 4.1 7.2 12.9 0.95 9.3 1.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlxA PF14282.1 OAP59722.1 - 4.5 7.2 9.0 9.6 6.2 0.4 2.4 1 1 0 1 1 1 0 FlxA-like protein TMF_DNA_bd PF12329.3 OAP59722.1 - 4.5 7.1 10.8 1.5 8.7 2.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 OAP59722.1 - 5 6.6 7.1 2.7 7.5 2.1 2.4 1 1 0 2 2 2 0 Septum formation initiator DUF607 PF04678.8 OAP59722.1 - 7.5 6.4 7.1 18 5.1 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 S4 PF01479.20 OAP59723.1 - 3.3e-15 55.2 0.0 5.5e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 OAP59723.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 S4 domain Pyr_redox_2 PF07992.9 OAP59724.1 - 3.2e-27 95.7 0.1 4.1e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP59724.1 - 7.5e-17 61.5 0.4 1.2e-14 54.4 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP59724.1 - 2.1e-09 37.7 0.1 2.9e-06 27.5 0.0 3.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 OAP59724.1 - 5.7e-05 23.3 0.1 0.0035 17.5 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 OAP59724.1 - 0.00015 20.9 0.3 0.0021 17.1 0.0 2.4 2 1 1 3 3 3 1 Thi4 family DAO PF01266.19 OAP59724.1 - 0.00023 20.1 3.5 1.6 7.5 0.2 3.5 2 2 1 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP59724.1 - 0.0003 20.7 0.5 0.14 12.2 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP59724.1 - 0.00031 19.7 0.0 0.016 14.1 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 OAP59724.1 - 0.0035 17.4 0.1 1.3 9.1 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 OAP59724.1 - 0.0084 15.2 0.6 0.81 8.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAP59724.1 - 0.011 14.7 0.0 2.5 7.0 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 OAP59724.1 - 0.066 12.0 5.6 2.3 6.9 0.2 3.6 2 2 2 4 4 4 0 FAD binding domain NAD_binding_9 PF13454.1 OAP59724.1 - 0.12 12.2 0.2 40 3.9 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 OAP59724.1 - 0.33 9.7 10.2 2.9 6.6 0.2 4.3 2 2 3 5 5 5 0 Glucose inhibited division protein A Hydrolase_like PF13242.1 OAP59725.1 - 0.039 13.6 0.0 0.086 12.5 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like Malic_M PF03949.10 OAP59726.1 - 3.9e-82 275.6 0.3 5.1e-82 275.2 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 OAP59726.1 - 1.6e-63 213.6 0.0 2.4e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Ribonuclease_T2 PF00445.13 OAP59726.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease T2 family Ldh_2 PF02615.9 OAP59727.1 - 5.6e-59 199.5 0.0 7.7e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Glyoxalase_2 PF12681.2 OAP59730.1 - 1.2e-11 45.2 0.0 1.4e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP59730.1 - 2.9e-05 24.0 0.1 0.0003 20.7 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.20 OAP59731.1 - 2.6e-21 76.2 0.9 2.5e-20 73.0 0.7 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59731.1 - 2.9e-16 59.9 0.0 1.4e-15 57.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59731.1 - 2.4e-08 33.8 0.0 3.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF2493 PF10686.4 OAP59731.1 - 0.052 13.1 0.4 1.1 8.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2493) p450 PF00067.17 OAP59732.1 - 3.8e-42 144.3 0.0 4.8e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Xan_ur_permease PF00860.15 OAP59733.1 - 2.7e-24 85.3 36.1 1.7e-23 82.7 22.4 3.0 2 1 0 2 2 2 1 Permease family ADH_N PF08240.7 OAP59734.1 - 2.2e-17 62.8 0.2 5e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP59734.1 - 3e-09 36.5 0.0 5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 OAP59734.1 - 0.0014 19.1 0.0 0.0041 17.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP59734.1 - 0.0031 17.0 0.1 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP59734.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAP59734.1 - 0.014 15.3 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAP59734.1 - 0.12 12.9 0.1 0.36 11.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 OAP59735.1 - 2e-91 306.8 22.5 4.7e-91 305.6 15.2 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59735.1 - 2.5e-13 49.4 41.9 2.4e-12 46.2 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PspA_IM30 PF04012.7 OAP59736.1 - 0.053 12.8 1.3 0.065 12.5 0.0 1.7 2 0 0 2 2 2 0 PspA/IM30 family adh_short PF00106.20 OAP59737.1 - 5.8e-18 65.3 0.3 2.8e-17 63.1 0.1 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 OAP59737.1 - 6.2e-10 39.0 0.0 9.9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP59737.1 - 6.2e-07 29.4 0.0 5.7e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP59737.1 - 0.0018 17.7 0.1 0.0037 16.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP59737.1 - 0.0038 15.9 0.0 0.007 15.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP59737.1 - 0.023 14.7 0.0 0.05 13.5 0.0 2.0 1 1 1 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAP59737.1 - 0.039 12.8 0.1 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 OAP59737.1 - 0.05 12.5 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase AAA_25 PF13481.1 OAP59738.1 - 1.5e-09 37.5 0.0 4.5e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 OAP59738.1 - 2e-05 23.8 0.0 8.8e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 KaiC Rad51 PF08423.6 OAP59738.1 - 0.00016 20.6 0.0 0.00094 18.1 0.0 2.1 2 1 0 2 2 2 1 Rad51 RecA PF00154.16 OAP59738.1 - 0.001 18.2 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 OAP59738.1 - 0.0022 17.7 0.4 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 OAP59738.1 - 0.0047 17.0 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 OAP59738.1 - 0.01 16.0 0.0 0.083 13.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 OAP59738.1 - 0.016 14.0 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_24 PF13479.1 OAP59738.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAP59738.1 - 0.035 13.8 0.0 0.079 12.6 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase ATP_bind_1 PF03029.12 OAP59738.1 - 0.061 12.8 0.1 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 OAP59738.1 - 0.062 13.2 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 OAP59738.1 - 0.093 12.1 0.0 0.25 10.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein ArgK PF03308.11 OAP59738.1 - 0.15 10.8 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Pkinase PF00069.20 OAP59739.1 - 2e-70 236.9 0.0 2.5e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP59739.1 - 3e-29 101.9 0.0 4.5e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP59739.1 - 7.8e-07 28.3 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAP59739.1 - 0.00028 20.6 0.1 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAP59739.1 - 0.001 18.1 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAP59739.1 - 0.038 13.3 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Cpn60_TCP1 PF00118.19 OAP59740.1 - 2.9e-145 484.6 0.3 3.3e-145 484.4 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop PF01798.13 OAP59741.1 - 1.5e-59 199.6 0.0 3.1e-59 198.5 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAP59741.1 - 1.5e-25 88.7 0.3 5.2e-25 87.0 0.5 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 OAP59741.1 - 2.2e-21 75.7 0.3 1.1e-20 73.5 0.0 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF606 PF04657.8 OAP59741.1 - 0.053 13.6 0.1 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF606 DUF3767 PF12597.3 OAP59743.1 - 6.3e-14 51.6 0.4 3.4e-11 42.8 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) DUF1744 PF08490.7 OAP59744.1 - 3.3e-142 473.7 0.2 4.6e-142 473.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 OAP59744.1 - 1.8e-65 220.9 0.5 3.3e-65 220.1 0.4 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 OAP59744.1 - 3.4e-23 82.1 0.0 4.2e-22 78.5 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 OAP59744.1 - 7.4e-08 32.1 0.0 2.1e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 OAP59744.1 - 0.00012 21.9 0.0 0.00057 19.7 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily TFIID_20kDa PF03847.8 OAP59745.1 - 4.6e-23 81.2 0.0 7.4e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A BAR_2 PF10455.4 OAP59747.1 - 1.8e-57 194.4 5.1 3e-57 193.7 3.5 1.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 OAP59747.1 - 1.3e-17 64.0 8.0 4.8e-16 58.9 5.5 2.0 1 1 0 1 1 1 1 BAR domain Arfaptin PF06456.8 OAP59747.1 - 0.042 13.2 1.5 0.1 11.9 0.0 2.2 2 0 0 2 2 2 0 Arfaptin-like domain zf-C4H2 PF10146.4 OAP59747.1 - 0.23 11.4 2.8 1.4 8.9 0.5 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Mob1_phocein PF03637.12 OAP59748.1 - 1.1e-23 83.7 0.6 1.9e-23 83.0 0.4 1.3 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 OAP59749.1 - 1.5e-11 44.1 0.3 1.7e-11 43.8 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 OAP59749.1 - 0.00058 19.5 0.1 0.00069 19.3 0.1 1.2 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 OAP59749.1 - 0.0014 19.0 0.0 0.0016 18.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAP59749.1 - 0.0048 16.9 0.0 0.0048 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 OAP59749.1 - 0.0048 16.6 0.0 0.0055 16.4 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 OAP59749.1 - 0.0055 16.9 0.2 0.0064 16.8 0.1 1.1 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 OAP59749.1 - 0.006 16.7 0.1 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 OAP59749.1 - 0.0083 15.8 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 OAP59749.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 OAP59749.1 - 0.01 15.3 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 OAP59749.1 - 0.012 15.5 0.1 0.015 15.2 0.1 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 OAP59749.1 - 0.012 14.7 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 OAP59749.1 - 0.012 15.8 0.2 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 OAP59749.1 - 0.012 15.4 0.2 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 OAP59749.1 - 0.016 14.2 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 OAP59749.1 - 0.024 14.3 0.1 0.027 14.1 0.1 1.1 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 OAP59749.1 - 0.025 13.4 0.1 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 OAP59749.1 - 0.035 13.7 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 OAP59749.1 - 0.059 12.9 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 OAP59749.1 - 0.087 11.5 0.0 0.094 11.4 0.0 1.1 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 OAP59750.1 - 3.1e-28 98.4 0.0 4.5e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 OAP59750.1 - 6.6e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Pkinase PF00069.20 OAP59751.1 - 6.5e-13 48.4 0.0 1.1e-11 44.4 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP59751.1 - 1.3e-11 44.0 0.0 1e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP59751.1 - 0.039 12.8 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SAP30_Sin3_bdg PF13867.1 OAP59752.1 - 4.9e-10 39.1 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-H2C2_2 PF13465.1 OAP59753.1 - 3.9e-09 36.3 20.3 2e-06 27.7 2.0 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAP59753.1 - 3.4e-05 23.9 13.5 0.0014 18.8 1.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP59753.1 - 0.0049 17.1 1.5 0.0049 17.1 1.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAP59753.1 - 0.093 12.9 2.9 0.35 11.0 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAP59753.1 - 0.12 12.3 2.1 7 6.7 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger BRO1 PF03097.13 OAP59754.1 - 2.4e-130 434.6 3.1 2.4e-130 434.6 2.2 3.0 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 OAP59754.1 - 1.9e-85 286.4 17.6 1.9e-85 286.4 12.2 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Med30 PF11315.3 OAP59754.1 - 0.91 9.6 9.1 0.031 14.3 1.0 2.5 3 0 0 3 3 3 0 Mediator complex subunit 30 CTDII PF01556.13 OAP59755.1 - 8.7e-27 92.8 0.2 1.1e-20 73.3 0.0 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 OAP59755.1 - 1.6e-22 78.9 2.9 3.1e-22 78.0 2.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 OAP59755.1 - 7.3e-12 45.1 17.7 1.3e-11 44.3 12.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Lon_C PF05362.8 OAP59756.1 - 2e-63 213.4 0.0 4.3e-63 212.3 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 OAP59756.1 - 4.7e-36 124.4 0.1 1.4e-35 122.8 0.1 1.9 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 OAP59756.1 - 6.4e-22 78.1 0.0 1.7e-21 76.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAP59756.1 - 1.2e-06 28.3 0.0 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAP59756.1 - 2.1e-06 27.7 0.0 6.1e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 OAP59756.1 - 5.7e-06 25.8 0.0 1.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 OAP59756.1 - 1.6e-05 25.0 0.0 0.00035 20.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP59756.1 - 3.3e-05 24.6 0.2 0.00028 21.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.6 OAP59756.1 - 3.4e-05 22.7 0.0 6.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 OAP59756.1 - 0.00016 21.6 4.3 0.00053 20.0 0.0 3.1 4 0 0 4 4 3 1 AAA ATPase domain RuvB_N PF05496.7 OAP59756.1 - 0.00018 20.6 0.0 0.0013 17.8 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 OAP59756.1 - 0.0012 19.1 4.8 0.031 14.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain SKI PF01202.17 OAP59756.1 - 0.0018 18.1 0.2 0.18 11.6 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA_14 PF13173.1 OAP59756.1 - 0.0081 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAP59756.1 - 0.015 14.6 0.0 0.075 12.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 OAP59756.1 - 0.029 14.0 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 OAP59756.1 - 0.041 13.0 0.0 0.096 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 OAP59756.1 - 0.058 13.5 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 OAP59756.1 - 0.079 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF445 PF04286.7 OAP59756.1 - 0.47 9.9 7.9 0.36 10.3 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) ABC_tran PF00005.22 OAP59756.1 - 0.62 10.3 4.1 0.71 10.1 0.0 2.9 3 0 0 3 3 3 0 ABC transporter KH_3 PF13014.1 OAP59758.1 - 0.035 13.7 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 KH domain KH_1 PF00013.24 OAP59758.1 - 0.042 13.4 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 KH domain DUF3682 PF12446.3 OAP59758.1 - 6.7 7.0 6.8 11 6.3 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) MFS_1 PF07690.11 OAP59759.1 - 3.3e-14 52.3 43.3 2.3e-13 49.6 30.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59759.1 - 2e-05 23.3 9.3 2e-05 23.3 6.5 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2839 PF10999.3 OAP59759.1 - 0.5 10.4 5.8 2.2 8.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Sugar_tr PF00083.19 OAP59761.1 - 6.2e-103 344.7 33.1 7.1e-103 344.5 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59761.1 - 5.3e-33 114.1 32.2 5.3e-33 114.1 22.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Lig_chan PF00060.21 OAP59761.1 - 0.74 9.5 7.2 2.2 8.0 0.1 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel p450 PF00067.17 OAP59762.1 - 1.2e-62 212.0 0.0 1.6e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 OAP59763.1 - 1.1e-49 168.8 0.0 1.7e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAP59763.1 - 1.4e-26 93.1 0.0 2.8e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAP59763.1 - 2.1e-18 66.8 0.1 5.9e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Pex2_Pex12 PF04757.9 OAP59765.1 - 0.037 13.4 0.1 0.055 12.8 0.1 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Rer1 PF03248.8 OAP59766.1 - 2e-81 271.7 3.5 2.3e-81 271.6 2.4 1.0 1 0 0 1 1 1 1 Rer1 family DUF4400 PF14348.1 OAP59766.1 - 0.23 10.8 5.3 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) ECH PF00378.15 OAP59767.1 - 4.5e-69 232.2 0.3 5.5e-69 231.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Aldedh PF00171.17 OAP59768.1 - 6.7e-160 532.4 0.1 7.5e-160 532.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP59768.1 - 3.6e-05 22.6 0.1 7.7e-05 21.5 0.1 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 OAP59768.1 - 0.00016 21.0 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Fungal_trans PF04082.13 OAP59769.1 - 0.00042 19.2 0.3 0.00072 18.5 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59769.1 - 0.012 15.5 5.4 0.023 14.5 3.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP59770.1 - 6.2e-40 136.9 48.9 1.1e-39 136.2 33.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP59770.1 - 7.6e-09 34.6 5.6 7.6e-09 34.6 3.9 3.6 2 1 2 4 4 4 3 Sugar (and other) transporter TRI12 PF06609.8 OAP59770.1 - 4.9e-08 31.6 21.9 1.1e-07 30.5 15.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.16 OAP59771.1 - 1.8e-21 76.6 0.0 2.4e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP59771.1 - 2.6e-12 46.0 0.0 3.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAP59771.1 - 7.5e-12 44.7 0.0 1.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 OAP59771.1 - 2.1e-09 37.6 0.0 4.6e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAP59771.1 - 1.3e-05 25.2 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAP59771.1 - 8.3e-05 21.6 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 OAP59771.1 - 0.00017 21.3 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 OAP59771.1 - 0.00059 19.1 0.0 0.0048 16.1 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family HHH_5 PF14520.1 OAP59772.1 - 0.0012 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.3 OAP59772.1 - 0.055 13.3 0.0 0.086 12.7 0.0 1.4 1 1 0 1 1 1 0 Pathogenicity locus DUF4332 PF14229.1 OAP59772.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Rtf2 PF04641.7 OAP59773.1 - 1.8e-61 207.6 6.0 3e-61 206.9 4.2 1.3 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 OAP59773.1 - 8.7e-07 28.3 0.0 0.00056 19.3 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 OAP59773.1 - 0.0001 21.9 1.9 0.00014 21.4 0.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 OAP59773.1 - 0.0014 18.2 0.3 0.0033 17.1 0.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAP59773.1 - 0.019 14.6 0.3 0.047 13.3 0.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP59773.1 - 0.033 14.0 2.2 4 7.3 0.0 2.9 3 0 0 3 3 3 0 Ring finger domain Plasmodium_Vir PF05795.6 OAP59773.1 - 0.047 12.8 3.4 0.08 12.1 2.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-C3HC4_2 PF13923.1 OAP59773.1 - 0.078 13.0 0.2 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DiS_P_DiS PF06750.8 OAP59773.1 - 0.17 11.6 0.3 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain MutS_V PF00488.16 OAP59774.1 - 9.9e-83 277.1 0.0 1.6e-82 276.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAP59774.1 - 6.6e-36 124.0 9.6 1.2e-35 123.1 6.6 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 OAP59774.1 - 1.1e-19 70.4 0.0 2.6e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 OAP59774.1 - 1.5e-10 41.2 0.0 9.5e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 OAP59774.1 - 0.016 15.3 0.0 0.078 13.1 0.0 2.1 2 0 0 2 2 2 0 MutS family domain IV AAA_29 PF13555.1 OAP59774.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain 3-HAO PF06052.7 OAP59775.1 - 4.1e-45 152.8 0.0 4.8e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Auxin_BP PF02041.11 OAP59775.1 - 0.0026 17.2 0.1 0.0034 16.8 0.1 1.2 1 0 0 1 1 1 1 Auxin binding protein Cupin_2 PF07883.6 OAP59775.1 - 0.0034 16.8 0.1 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 OAP59775.1 - 0.069 12.8 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC_insert PF05189.8 OAP59776.1 - 6.4e-32 109.6 0.0 1.2e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 OAP59776.1 - 2.2e-29 101.8 0.0 3.7e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PAP2_3 PF14378.1 OAP59777.1 - 1e-18 67.5 17.1 2.1e-10 40.4 0.2 4.2 4 1 0 4 4 4 3 PAP2 superfamily PWWP PF00855.12 OAP59778.1 - 2.7e-15 56.3 0.0 2.7e-15 56.3 0.0 2.8 3 1 0 3 3 3 1 PWWP domain DNA_mis_repair PF01119.14 OAP59778.1 - 0.0015 17.9 0.1 0.033 13.6 0.0 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain DUF2935 PF11155.3 OAP59778.1 - 0.027 14.5 0.4 0.059 13.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Pkinase PF00069.20 OAP59779.1 - 4.6e-37 127.5 0.0 5.5e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP59779.1 - 1.5e-11 43.9 0.0 0.00081 18.5 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 OAP59779.1 - 1.7e-06 27.9 0.5 6.6e-06 26.0 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP59779.1 - 0.053 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3456 PF11938.3 OAP59779.1 - 0.081 12.9 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP DUF3043 PF11241.3 OAP59779.1 - 4.2 6.9 6.7 7.6 6.0 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Sec63 PF02889.11 OAP59780.1 - 3e-188 624.5 0.0 7.1e-105 350.6 0.0 2.8 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 OAP59780.1 - 4e-53 179.3 0.1 1.5e-30 105.9 0.0 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 OAP59780.1 - 3e-18 66.3 0.0 3.8e-09 36.6 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAP59780.1 - 3.6e-10 39.5 0.0 2.1e-08 33.8 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 OAP59780.1 - 3.2e-08 33.7 0.0 0.00054 20.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 OAP59780.1 - 0.00083 18.6 0.0 0.1 11.8 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 OAP59780.1 - 0.001 18.5 0.1 7.2 5.9 0.0 4.6 4 1 1 5 5 5 2 AAA-like domain T2SE PF00437.15 OAP59780.1 - 0.0015 17.4 0.0 0.39 9.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.1 OAP59780.1 - 0.012 15.3 0.0 1.4 8.6 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 OAP59780.1 - 0.051 13.0 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 OAP59780.1 - 1.3 9.2 4.3 7.4 6.8 0.0 3.7 4 0 0 4 4 4 0 AAA domain Acetyltransf_1 PF00583.19 OAP59781.1 - 0.007 16.3 0.0 0.035 14.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP59781.1 - 0.033 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP59781.1 - 0.07 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein Ank_4 PF13637.1 OAP59781.1 - 0.071 13.6 0.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Thiolase_N PF00108.18 OAP59782.1 - 7.1e-79 264.4 0.3 9.5e-79 264.0 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAP59782.1 - 4.7e-41 139.0 0.2 1.3e-40 137.6 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAP59782.1 - 0.0055 16.2 0.7 0.017 14.6 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 OAP59782.1 - 0.055 13.1 0.9 3 7.5 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_L50 PF10501.4 OAP59783.1 - 0.00011 22.1 0.1 0.00037 20.4 0.0 2.0 2 1 0 2 2 2 1 Ribosomal subunit 39S TerB-C PF15615.1 OAP59783.1 - 6.8 6.9 9.7 1.7 8.8 3.6 2.4 2 1 0 2 2 2 0 TerB-C domain Methyltransf_16 PF10294.4 OAP59784.1 - 1.4e-20 73.4 0.0 2.3e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAP59784.1 - 0.0071 16.9 0.0 0.023 15.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP59784.1 - 0.0071 16.0 0.0 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP59784.1 - 0.009 16.0 0.1 0.031 14.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP59784.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.11 OAP59785.1 - 3.4e-34 118.1 29.2 3.4e-34 118.1 20.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 OAP59785.1 - 3.7 7.6 8.3 1.7 8.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Fungal_trans_2 PF11951.3 OAP59786.1 - 0.026 13.1 0.0 0.046 12.3 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF899 PF05988.7 OAP59787.1 - 1.6e-72 243.3 0.0 2e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.16 OAP59787.1 - 0.067 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family p450 PF00067.17 OAP59788.1 - 3.9e-60 203.6 0.0 4.8e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhzC-PhzF PF02567.11 OAP59790.1 - 1.3e-19 70.5 0.0 6.8e-17 61.5 0.0 2.3 1 1 0 2 2 2 2 Phenazine biosynthesis-like protein Zn_clus PF00172.13 OAP59790.1 - 1.2e-08 34.7 7.6 3.5e-08 33.2 5.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_5 PF13857.1 OAP59791.1 - 0.0027 17.8 0.0 0.0082 16.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAP59791.1 - 0.067 13.5 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF1294 PF06961.8 OAP59791.1 - 0.13 12.2 1.3 0.31 11.0 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) polyprenyl_synt PF00348.12 OAP59792.1 - 2.8e-50 170.5 0.0 2e-47 161.2 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase HTH_Tnp_Tc3_2 PF01498.13 OAP59792.1 - 0.015 15.3 0.7 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Transposase HEPPP_synt_1 PF07307.6 OAP59792.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 AMMECR1 PF01871.12 OAP59793.1 - 1.5e-39 134.8 0.0 3e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 AMMECR1 Prothymosin PF03247.9 OAP59793.1 - 0.0055 16.8 15.8 0.0091 16.1 11.0 1.2 1 0 0 1 1 1 1 Prothymosin/parathymosin family Macoilin PF09726.4 OAP59793.1 - 0.014 13.7 1.7 0.012 13.9 1.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Nop14 PF04147.7 OAP59793.1 - 0.63 7.8 10.5 0.82 7.5 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 OAP59793.1 - 1 7.7 11.3 1.4 7.2 7.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PBP1_TM PF14812.1 OAP59793.1 - 1.3 9.3 10.2 2.7 8.3 7.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 OAP59793.1 - 4.1 5.1 10.2 7.2 4.3 7.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 OAP59793.1 - 9.2 4.1 11.4 12 3.7 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.2 OAP59794.1 - 1.6e-44 150.1 1.5 1e-13 51.3 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 OAP59794.1 - 9.3e-30 100.9 1.4 2.4e-07 30.2 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 OAP59794.1 - 1.1e-28 99.0 8.8 2.6e-08 34.1 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP59794.1 - 3.3e-23 81.1 2.6 7.7e-08 32.3 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP59794.1 - 3.6e-17 60.7 6.4 0.0014 18.6 0.0 5.9 5 1 0 5 5 5 4 Ankyrin repeat adh_short PF00106.20 OAP59795.1 - 2.1e-21 76.5 0.0 3.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59795.1 - 1.8e-09 37.6 0.0 2.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59795.1 - 0.00015 21.4 0.1 0.00041 20.0 0.0 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP59795.1 - 0.00025 21.0 0.0 0.00068 19.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Peptidase_S21 PF00716.12 OAP59795.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Erg28 PF03694.8 OAP59796.1 - 1.3e-30 105.6 0.1 1.8e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Erg28 like protein Cellsynth_D PF03500.8 OAP59796.1 - 0.099 12.3 0.2 0.15 11.7 0.1 1.3 1 1 0 1 1 1 0 Cellulose synthase subunit D GalP_UDP_transf PF01087.17 OAP59797.1 - 3.6e-68 229.2 0.0 8.1e-67 224.8 0.0 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 OAP59797.1 - 8.3e-57 191.3 0.0 1.6e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 OAP59797.1 - 0.0014 19.0 0.0 0.005 17.3 0.0 1.9 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 OAP59797.1 - 0.08 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding F-box-like PF12937.2 OAP59798.1 - 2.5e-07 30.2 0.5 5.2e-07 29.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP59798.1 - 0.0013 18.3 2.3 0.0013 18.3 1.6 1.7 2 0 0 2 2 2 1 F-box domain DUF566 PF04484.7 OAP59799.1 - 7.1 6.0 8.7 9 5.7 6.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Clr5 PF14420.1 OAP59800.1 - 5.3e-14 51.8 0.2 1.5e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_10 PF13374.1 OAP59800.1 - 0.013 15.3 0.2 36 4.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Gag_spuma PF03276.9 OAP59801.1 - 0.081 11.2 2.6 0.081 11.2 1.8 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF1283 PF06932.6 OAP59801.1 - 0.32 11.0 2.1 0.38 10.8 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1283) Pneumo_att_G PF05539.6 OAP59801.1 - 0.67 9.2 3.7 0.63 9.3 2.6 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G APH PF01636.18 OAP59802.1 - 3.4e-11 43.3 0.1 5.1e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sirohm_synth_C PF14823.1 OAP59802.1 - 0.24 10.7 0.9 13 5.1 0.0 2.7 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal Glyco_hydro_47 PF01532.15 OAP59804.1 - 4.3e-130 434.3 0.0 5.4e-130 434.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 EcoRII-C PF09019.6 OAP59804.1 - 0.23 11.2 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 EcoRII C terminal Epimerase PF01370.16 OAP59805.1 - 7.3e-15 55.0 0.1 1.9e-14 53.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP59805.1 - 2.6e-14 52.5 0.0 3.5e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAP59805.1 - 2.9e-11 42.7 0.1 3.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 OAP59805.1 - 4e-11 43.2 0.0 1.3e-10 41.5 0.0 1.8 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 OAP59805.1 - 1.8e-06 28.0 0.0 1.8e-06 28.0 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 OAP59805.1 - 1.5e-05 24.7 0.0 4.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 OAP59805.1 - 0.0014 17.9 0.1 0.0055 15.9 0.1 2.0 1 1 0 1 1 1 1 NmrA-like family Fungal_trans PF04082.13 OAP59806.1 - 2.8e-17 62.4 0.8 4.1e-17 61.9 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59806.1 - 3e-05 23.8 13.6 5.3e-05 23.0 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP59807.1 - 1e-25 90.1 0.6 1.6e-25 89.4 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59807.1 - 6.5e-07 29.1 13.4 1.3e-06 28.2 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain chaperone_DMP PF10448.4 OAP59808.1 - 0.0075 16.1 0.0 0.0077 16.1 0.0 1.1 1 0 0 1 1 1 1 20S proteasome chaperone N2227 PF07942.7 OAP59809.1 - 1.4e-85 286.5 0.0 1.8e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 OAP59809.1 - 0.00066 19.4 0.0 0.0018 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP59809.1 - 0.022 15.2 0.0 0.76 10.2 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAP59809.1 - 0.087 13.3 0.0 0.7 10.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain HSP70 PF00012.15 OAP59810.1 - 2.5e-11 42.2 0.5 1.2e-09 36.6 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 OAP59810.1 - 0.0044 16.6 0.1 0.0098 15.5 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 OAP59810.1 - 0.051 12.1 0.1 0.22 10.0 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.15 OAP59811.1 - 4.8e-61 206.4 0.4 1.1e-56 192.0 0.1 2.3 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 OAP59811.1 - 0.013 14.1 0.0 0.03 12.9 0.0 1.6 1 0 0 1 1 1 0 MreB/Mbl protein Tubulin_3 PF14881.1 OAP59812.1 - 2.3e-77 258.5 0.2 1.2e-76 256.2 0.1 2.1 3 0 0 3 3 3 1 Tubulin domain Misat_Tub_SegII PF10644.4 OAP59812.1 - 2.4e-39 133.9 0.0 6.2e-39 132.6 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 OAP59812.1 - 1.8e-05 24.6 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Sec66 PF09802.4 OAP59812.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF1479 PF07350.7 OAP59814.1 - 1.9e-120 402.1 0.0 2.1e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sugar_tr PF00083.19 OAP59815.1 - 1.8e-78 264.1 28.1 2.1e-78 263.9 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59815.1 - 2e-21 76.1 34.4 2e-21 76.1 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2762 PF10960.3 OAP59815.1 - 0.059 13.0 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) DUF1628 PF07790.6 OAP59815.1 - 0.2 12.4 1.9 0.58 10.9 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) Fungal_trans PF04082.13 OAP59816.1 - 5.9e-16 58.1 0.0 9.4e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59816.1 - 0.0068 16.2 2.2 0.013 15.4 1.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PMI_typeI PF01238.16 OAP59817.1 - 7.6e-73 245.6 0.0 1.8e-72 244.4 0.0 1.5 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 OAP59817.1 - 3.1e-05 23.6 0.1 0.00039 20.1 0.0 2.7 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_2 PF07883.6 OAP59817.1 - 0.00064 19.1 0.1 0.043 13.3 0.1 2.3 2 0 0 2 2 2 1 Cupin domain AraC_N PF06719.8 OAP59817.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus C1_3 PF07649.7 OAP59818.1 - 0.0071 16.3 3.8 0.0071 16.3 2.7 2.0 2 0 0 2 2 2 1 C1-like domain zinc-ribbons_6 PF07191.7 OAP59818.1 - 8.4 6.2 9.4 1.8 8.4 3.3 2.1 2 0 0 2 2 2 0 zinc-ribbons CoA_binding_2 PF13380.1 OAP59819.1 - 5.6e-24 84.5 0.0 6.9e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 OAP59819.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.4 1 1 0 1 1 1 0 CoA binding domain AA_permease PF00324.16 OAP59822.1 - 3e-91 306.1 43.7 3.8e-91 305.8 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP59822.1 - 2.9e-25 88.6 47.3 3.6e-25 88.3 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 OAP59822.1 - 0.039 13.6 0.3 0.039 13.6 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) PEP_mutase PF13714.1 OAP59823.1 - 1.6e-57 194.5 2.1 1.8e-57 194.3 1.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF3253 PF11625.3 OAP59823.1 - 0.027 14.3 0.1 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Fungal_trans_2 PF11951.3 OAP59824.1 - 2e-09 36.5 2.1 2.4e-09 36.2 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain NRDE PF05742.7 OAP59825.1 - 5.6e-45 153.7 0.0 4.3e-44 150.8 0.0 1.9 1 1 0 1 1 1 1 NRDE protein TB2_DP1_HVA22 PF03134.14 OAP59826.1 - 7.8e-26 89.6 6.5 1.2e-25 89.1 4.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family zf-RING_2 PF13639.1 OAP59827.1 - 6.5e-15 54.6 4.3 1.1e-14 53.9 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAP59827.1 - 1.1e-07 31.8 1.2 2e-07 31.0 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 OAP59827.1 - 2.4e-07 30.6 4.9 4e-07 29.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP59827.1 - 8e-07 28.6 3.7 1.3e-06 27.8 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP59827.1 - 2e-06 27.4 2.8 3.3e-06 26.7 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAP59827.1 - 5.2e-05 22.8 1.9 9e-05 22.0 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAP59827.1 - 0.0047 16.7 1.4 0.01 15.6 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 OAP59827.1 - 0.0063 16.0 2.9 0.011 15.3 2.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.24 OAP59827.1 - 0.04 13.6 2.9 0.073 12.7 2.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 OAP59827.1 - 0.076 13.0 3.2 0.14 12.2 2.2 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 OAP59827.1 - 0.77 9.7 3.8 3.8 7.5 2.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Pyr_redox_3 PF13738.1 OAP59829.1 - 1.3e-10 41.6 0.0 2.3e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP59829.1 - 4.5e-05 22.5 0.0 6.6e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP59829.1 - 0.00044 20.1 0.0 0.00048 20.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FA_desaturase PF00487.19 OAP59831.1 - 2e-20 73.2 11.0 4e-20 72.3 7.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 OAP59831.1 - 2.6e-16 59.1 0.1 6.6e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain U-box PF04564.10 OAP59832.1 - 2.1e-22 78.8 0.1 5.1e-22 77.6 0.0 1.7 2 0 0 2 2 1 1 U-box domain TPR_11 PF13414.1 OAP59832.1 - 1e-14 53.9 7.1 6.9e-13 48.0 0.3 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAP59832.1 - 4.5e-09 35.5 9.7 0.014 15.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAP59832.1 - 1.5e-05 25.5 7.9 0.0094 16.6 0.9 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAP59832.1 - 4.7e-05 22.8 5.9 0.0023 17.4 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 OAP59832.1 - 0.0036 17.3 4.9 0.016 15.2 3.2 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 OAP59832.1 - 0.0057 16.5 11.7 0.35 10.8 0.1 3.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAP59832.1 - 0.042 13.6 0.0 0.042 13.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAP59832.1 - 0.044 13.9 1.8 19 5.8 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAP59832.1 - 0.047 13.6 9.6 4.5 7.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAP59832.1 - 0.056 13.7 6.8 27 5.2 4.7 2.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP59832.1 - 0.12 13.0 11.7 1.9 9.3 0.0 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat zf-Nse PF11789.3 OAP59832.1 - 0.14 11.6 0.0 0.4 10.2 0.0 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_6 PF13174.1 OAP59832.1 - 0.25 11.8 4.8 5.6 7.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ACBP PF00887.14 OAP59833.1 - 2.5e-23 81.5 0.5 2.8e-23 81.3 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.27 OAP59834.1 - 4.4e-18 64.4 6.7 0.00093 18.9 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF822 PF05687.8 OAP59834.1 - 1.1 9.6 9.1 1.7 8.9 6.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) SOG2 PF10428.4 OAP59834.1 - 2.4 6.7 11.4 3.4 6.2 7.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Nucleoplasmin PF03066.10 OAP59834.1 - 8.6 5.8 8.3 15 5.1 5.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Glycos_transf_4 PF00953.16 OAP59835.1 - 6.7e-31 107.2 9.0 6.7e-31 107.2 6.3 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 4 Tyr-DNA_phospho PF06087.7 OAP59836.1 - 2.6e-124 415.2 0.0 3.3e-124 414.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 OAP59836.1 - 5.8e-05 22.8 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Rad4 PF03835.10 OAP59837.1 - 3.8e-33 113.9 0.1 1.3e-32 112.2 0.0 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 OAP59837.1 - 3e-29 100.5 0.2 5e-29 99.8 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 OAP59837.1 - 1e-16 60.9 0.5 5.8e-16 58.5 0.4 2.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 OAP59837.1 - 1.4e-16 59.7 0.0 3.4e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 OAP59837.1 - 0.0013 18.9 0.0 0.0066 16.6 0.0 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily EF-hand_7 PF13499.1 OAP59838.1 - 4.3e-14 52.4 0.1 2.7e-09 37.0 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 OAP59838.1 - 2.2e-11 42.6 0.2 0.0012 18.5 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 OAP59838.1 - 1.6e-09 36.3 0.6 0.013 14.7 0.0 3.7 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 OAP59838.1 - 2.5e-08 33.6 0.0 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 OAP59838.1 - 2.3e-06 27.1 1.0 0.00014 21.4 0.1 3.0 2 2 2 4 4 4 1 EF-hand domain pair UPF0154 PF03672.8 OAP59838.1 - 0.042 13.4 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3216 PF11505.3 OAP59838.1 - 0.057 13.2 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) EF-hand_5 PF13202.1 OAP59838.1 - 0.12 11.7 1.5 2.2 7.7 0.7 3.0 3 0 0 3 3 3 0 EF hand 2OG-FeII_Oxy PF03171.15 OAP59839.1 - 7e-19 67.9 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP59839.1 - 2.5e-16 60.2 0.0 1e-10 42.1 0.0 2.4 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal Transp_cyt_pur PF02133.10 OAP59840.1 - 7.7e-34 116.9 28.3 9.8e-34 116.6 19.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AA_permease_2 PF13520.1 OAP59841.1 - 1.6e-36 125.8 55.9 2e-36 125.4 38.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP59841.1 - 7.8e-18 64.0 45.2 1.1e-17 63.5 31.3 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_M13_N PF05649.8 OAP59842.1 - 7.6e-92 308.3 0.0 1.2e-91 307.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 OAP59842.1 - 4.4e-57 192.5 0.0 7.3e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 SET PF00856.23 OAP59843.1 - 1.3e-05 25.5 0.0 0.0081 16.4 0.0 2.8 1 1 1 2 2 2 2 SET domain Protocadherin PF08374.6 OAP59843.1 - 0.14 11.7 0.9 0.19 11.3 0.6 1.2 1 0 0 1 1 1 0 Protocadherin p450 PF00067.17 OAP59844.1 - 1.6e-31 109.3 0.0 2.4e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Response_reg PF00072.19 OAP59846.1 - 6.8e-25 87.2 0.4 1.6e-24 86.0 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 OAP59846.1 - 3.8e-24 84.5 0.0 1e-23 83.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAP59846.1 - 2.2e-17 62.7 1.2 3.7e-17 62.0 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 OAP59846.1 - 2.3e-16 60.0 0.0 1.6e-14 54.1 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 OAP59846.1 - 7.4e-16 58.1 0.0 6.2e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 OAP59846.1 - 2e-12 46.9 0.0 1.2e-08 34.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold Acetyltransf_1 PF00583.19 OAP59848.1 - 2e-09 37.3 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP59848.1 - 4.4e-07 29.9 0.0 7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP59848.1 - 0.00045 20.0 0.0 0.075 12.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP59848.1 - 0.022 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP59848.1 - 0.029 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Asp_protease PF09668.5 OAP59849.1 - 1.3e-57 192.7 0.1 2.1e-57 192.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 OAP59849.1 - 2e-12 47.4 0.2 6.1e-12 45.8 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 OAP59849.1 - 4.5e-10 39.0 0.0 9.2e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 OAP59849.1 - 4.3e-08 33.1 0.0 7.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAP59849.1 - 1.9e-07 30.8 0.3 6e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.18 OAP59849.1 - 3.9e-07 29.3 0.0 7.3e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RVP PF00077.15 OAP59849.1 - 4.5e-07 29.7 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 OAP59849.1 - 0.014 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.11 OAP59849.1 - 0.025 14.0 0.0 0.086 12.3 0.0 2.0 2 0 0 2 2 2 0 CUE domain NOT2_3_5 PF04153.13 OAP59850.1 - 2.2e-29 102.0 0.4 4.4e-29 101.0 0.3 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family AAA_13 PF13166.1 OAP59851.1 - 0.01 14.3 0.3 0.014 13.8 0.2 1.1 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 OAP59851.1 - 0.021 15.0 0.3 2 8.7 0.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 OAP59851.1 - 0.64 9.8 8.1 1.2 9.0 3.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 dCMP_cyt_deam_1 PF00383.17 OAP59852.1 - 4e-08 32.8 0.0 1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 OAP59852.1 - 0.085 12.7 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase Pribosyltran PF00156.22 OAP59853.1 - 9.3e-16 57.6 0.3 1.7e-15 56.8 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PEP-utilisers_N PF05524.8 OAP59853.1 - 0.024 14.4 0.4 0.041 13.6 0.3 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal PRTase_2 PF15609.1 OAP59853.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase MTHFR PF02219.12 OAP59854.1 - 6.6e-115 383.1 0.0 8.9e-115 382.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Hexokinase_2 PF03727.11 OAP59856.1 - 2.7e-35 121.7 0.0 3.9e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 OAP59856.1 - 3.6e-33 114.6 0.0 5.7e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase YgaB PF14182.1 OAP59857.1 - 0.065 13.4 1.8 1.9 8.8 0.1 2.4 2 0 0 2 2 2 0 YgaB-like protein FAA_hydrolase PF01557.13 OAP59858.1 - 3.8e-51 173.6 0.0 4.9e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Gly-zipper_OmpA PF13436.1 OAP59859.1 - 0.018 14.7 1.6 0.018 14.7 1.1 2.3 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DEAD PF00270.24 OAP59860.1 - 2.9e-43 147.2 1.3 5.5e-43 146.3 0.5 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP59860.1 - 7.3e-28 96.2 0.4 3.7e-27 93.9 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP59860.1 - 0.00055 19.8 0.0 0.0013 18.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 OAP59860.1 - 0.0074 15.3 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 OAP59860.1 - 0.0076 15.8 0.0 0.025 14.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP59860.1 - 0.026 14.6 0.5 0.12 12.5 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAP59860.1 - 0.041 13.6 0.1 0.16 11.7 0.1 2.0 1 1 0 1 1 1 0 Part of AAA domain SNF2_N PF00176.18 OAP59860.1 - 0.063 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain CobA_CobO_BtuR PF02572.10 OAP59860.1 - 0.08 12.5 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Cupin_8 PF13621.1 OAP59861.1 - 4.4e-16 59.1 0.6 4.3e-15 55.9 0.1 2.5 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 OAP59861.1 - 3.3e-10 40.2 0.1 1.1e-09 38.5 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 OAP59861.1 - 1.6e-05 24.5 0.1 3.6e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP59861.1 - 4e-05 23.1 0.0 0.00012 21.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ctr PF04145.10 OAP59862.1 - 3.3e-32 111.4 5.6 5.1e-32 110.9 3.9 1.3 1 1 0 1 1 1 1 Ctr copper transporter family NuA4 PF09340.5 OAP59863.1 - 3.8e-26 90.5 0.6 9.4e-26 89.2 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Toxin_42 PF15522.1 OAP59863.1 - 0.044 12.9 0.1 0.082 12.0 0.0 1.5 1 1 0 1 1 1 0 Putative toxin 42 NUDIX PF00293.23 OAP59864.1 - 2.2e-13 50.0 0.1 3.8e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain GHL12 PF14882.1 OAP59864.1 - 0.057 13.5 3.1 0.13 12.3 2.1 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 Cren7 PF11520.3 OAP59864.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin protein Cren7 Glyco_hydro_38 PF01074.17 OAP59866.1 - 6.7e-91 304.3 1.0 6.7e-91 304.3 0.7 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 OAP59866.1 - 3.1e-71 240.5 0.0 7.6e-71 239.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 OAP59866.1 - 1.3e-26 92.5 0.1 2.6e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain AAA_11 PF13086.1 OAP59866.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain CAP_GLY PF01302.20 OAP59867.1 - 2.2e-16 59.2 0.3 4.6e-16 58.2 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain Fez1 PF06818.10 OAP59867.1 - 0.00038 20.5 30.6 0.13 12.2 13.2 3.1 3 0 0 3 3 3 2 Fez1 Myosin_tail_1 PF01576.14 OAP59867.1 - 0.081 10.6 42.2 0.0051 14.6 4.2 2.8 2 1 1 3 3 3 0 Myosin tail DELLA PF12041.3 OAP59867.1 - 0.081 12.5 0.8 0.24 11.0 0.6 1.8 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DUF812 PF05667.6 OAP59867.1 - 0.23 9.9 31.7 0.0053 15.3 11.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF812) NPV_P10 PF05531.7 OAP59867.1 - 0.24 11.6 21.5 0.15 12.2 2.3 4.6 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 OAP59867.1 - 0.31 10.7 29.1 0.024 14.4 8.2 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 OAP59867.1 - 0.35 9.2 22.6 0.02 13.4 8.5 2.4 2 1 1 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 OAP59867.1 - 0.95 8.5 6.7 5 6.2 0.5 3.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TcdB_N PF12918.2 OAP59867.1 - 1 9.5 6.8 11 6.1 0.2 3.4 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain PilJ PF13675.1 OAP59867.1 - 1.1 9.5 17.4 0.099 12.9 1.9 3.8 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fib_alpha PF08702.5 OAP59867.1 - 1.1 9.3 19.5 0.16 12.0 1.0 3.9 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family EAP30 PF04157.11 OAP59867.1 - 1.4 7.9 11.6 0.29 10.2 1.0 3.0 1 1 2 3 3 3 0 EAP30/Vps36 family Tropomyosin_1 PF12718.2 OAP59867.1 - 3.6 7.4 48.7 1.3 8.8 5.4 4.1 2 1 1 4 4 4 0 Tropomyosin like Laminin_II PF06009.7 OAP59867.1 - 3.8 7.2 21.2 0.41 10.3 1.3 3.2 2 2 0 3 3 3 0 Laminin Domain II DUF3584 PF12128.3 OAP59867.1 - 7.6 3.7 31.1 23 2.1 21.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) EzrA PF06160.7 OAP59867.1 - 7.9 4.5 26.5 0.43 8.6 1.3 3.2 2 1 2 4 4 4 0 Septation ring formation regulator, EzrA ATP-synt_DE PF00401.15 OAP59868.1 - 0.17 11.7 1.9 0.32 10.9 1.3 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain AA_permease PF00324.16 OAP59869.1 - 5.2e-138 460.3 38.2 5.9e-138 460.1 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP59869.1 - 1.3e-37 129.3 40.9 1.7e-37 129.0 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease FMN_dh PF01070.13 OAP59870.1 - 6.4e-120 400.2 0.0 8.1e-120 399.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAP59870.1 - 2.1e-24 85.0 0.0 4.2e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAP59870.1 - 2.9e-09 36.3 0.0 5.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 OAP59870.1 - 0.00028 20.1 1.0 0.00038 19.7 0.1 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.20 OAP59870.1 - 0.00047 19.1 0.6 0.00085 18.3 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 OAP59870.1 - 0.034 13.4 0.9 0.67 9.1 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein Toxin_55 PF15606.1 OAP59870.1 - 0.11 12.4 0.4 0.28 11.1 0.3 1.6 1 0 0 1 1 1 0 Putative toxin 55 ThiG PF05690.9 OAP59870.1 - 0.11 11.5 0.1 6.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF676 PF05057.9 OAP59871.1 - 3.6e-40 137.5 0.1 8.7e-26 90.5 0.0 3.7 4 0 0 4 4 4 3 Putative serine esterase (DUF676) DUF3597 PF12200.3 OAP59871.1 - 0.0093 16.3 0.7 0.046 14.1 0.5 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3597) MFS_1 PF07690.11 OAP59872.1 - 2.4e-18 66.0 27.4 3.9e-18 65.2 19.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAP59872.1 - 1.4e-10 40.8 6.9 1.4e-10 40.8 4.8 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Amidohydro_4 PF13147.1 OAP59873.1 - 2.4e-13 50.7 0.0 1.1e-06 28.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 OAP59873.1 - 3.1e-13 50.1 0.0 5.4e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 OAP59873.1 - 2.6e-05 23.9 0.0 5.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP59873.1 - 0.00021 20.6 0.0 0.00052 19.3 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase family Peptidase_S9 PF00326.16 OAP59874.1 - 1.3e-51 174.9 0.0 2.1e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP59874.1 - 1.2e-09 38.1 0.0 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAP59874.1 - 0.0037 15.8 0.2 0.21 10.0 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) PD40 PF07676.7 OAP59874.1 - 0.017 14.7 0.1 0.38 10.4 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat YqeY PF09424.5 OAP59875.1 - 3.8e-14 52.7 5.3 4.4e-14 52.5 3.7 1.1 1 0 0 1 1 1 1 Yqey-like protein Nucleoporin_C PF03177.9 OAP59876.1 - 6.1e-127 424.5 8.5 8.9e-127 424.0 5.9 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 OAP59876.1 - 2e-87 293.6 0.1 2.8e-87 293.2 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like SUI1 PF01253.17 OAP59876.1 - 0.028 14.2 0.0 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor SUI1 DUF2781 PF10914.3 OAP59877.1 - 1.8e-33 115.4 13.3 2.2e-33 115.1 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) LacAB_rpiB PF02502.13 OAP59878.1 - 3.2e-43 146.7 0.5 3.7e-43 146.5 0.4 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 OAP59878.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.4 1 1 0 1 1 1 0 Glycine-rich SFCGS BTB PF00651.26 OAP59879.1 - 2.5e-16 59.6 0.0 4.1e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-HIT PF04438.11 OAP59879.1 - 0.0016 18.0 2.9 0.003 17.1 2.0 1.3 1 0 0 1 1 1 1 HIT zinc finger Zn_Tnp_IS1595 PF12760.2 OAP59879.1 - 0.0075 16.0 4.3 0.016 14.9 3.0 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain TIM PF00121.13 OAP59881.1 - 4.1e-39 134.0 0.0 3.2e-38 131.1 0.0 1.9 2 0 0 2 2 2 1 Triosephosphate isomerase SMC_N PF02463.14 OAP59882.1 - 1.1e-70 237.3 0.0 2.7e-70 236.0 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAP59882.1 - 1.5e-23 83.0 0.6 1.3e-21 76.7 0.1 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAP59882.1 - 2.9e-12 47.1 3.1 5.4e-05 23.3 0.1 3.4 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.22 OAP59882.1 - 0.00052 20.3 0.0 0.00052 20.3 0.0 6.6 5 2 0 5 5 4 2 ABC transporter AAA_29 PF13555.1 OAP59882.1 - 0.00053 19.4 0.1 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 OAP59882.1 - 0.00099 18.3 7.2 0.00099 18.3 5.0 7.4 2 2 3 7 7 6 3 Growth-arrest specific micro-tubule binding IncA PF04156.9 OAP59882.1 - 0.0017 17.9 108.9 0.15 11.6 5.8 6.7 2 2 4 6 6 6 4 IncA protein Reo_sigmaC PF04582.7 OAP59882.1 - 0.0023 17.1 39.7 0.039 13.1 1.9 5.8 3 2 3 6 6 6 3 Reovirus sigma C capsid protein AAA_23 PF13476.1 OAP59882.1 - 0.003 17.9 39.6 0.003 17.9 27.4 6.4 2 2 2 4 4 3 1 AAA domain Mnd1 PF03962.10 OAP59882.1 - 0.0051 16.4 10.7 0.0051 16.4 7.4 7.5 3 2 4 7 7 5 2 Mnd1 family MscS_porin PF12795.2 OAP59882.1 - 7.3 5.8 95.8 0.12 11.6 16.3 5.8 3 2 3 6 6 6 0 Mechanosensitive ion channel porin domain MRP-L47 PF06984.8 OAP59883.1 - 6e-22 77.3 0.2 9.2e-22 76.7 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Fungal_trans PF04082.13 OAP59884.1 - 1.9e-14 53.1 3.5 2.6e-14 52.7 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 OAP59885.1 - 7.9e-06 25.2 0.0 8.9e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 OAP59885.1 - 0.00014 21.4 0.0 0.0044 16.4 0.0 2.5 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP59885.1 - 0.00051 20.0 0.0 0.0025 17.8 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 OAP59886.1 - 3.8e-29 102.1 0.1 4.6e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP59886.1 - 1.2e-25 90.3 0.5 1.4e-25 90.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP59886.1 - 1.4e-08 34.5 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP59886.1 - 0.02 14.6 1.2 0.032 14.0 0.3 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AdoHcyase_NAD PF00670.16 OAP59886.1 - 0.082 12.7 1.2 0.17 11.6 0.8 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TPP_enzyme_N PF02776.13 OAP59887.1 - 3.6e-33 114.4 0.2 6.3e-33 113.6 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP59887.1 - 1.4e-21 76.7 0.0 7.5e-21 74.3 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 OAP59887.1 - 4.7e-15 55.4 0.2 1.1e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GDI PF00996.13 OAP59888.1 - 1.1e-181 603.9 0.0 1.5e-181 603.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 OAP59888.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Hep_59 PF07052.6 OAP59889.1 - 0.0058 16.9 0.7 0.063 13.6 0.1 2.5 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Fungal_trans_2 PF11951.3 OAP59890.1 - 5.3e-19 68.0 0.3 2.2e-18 66.0 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.10 OAP59891.1 - 2e-55 187.7 0.0 6e-52 176.4 0.0 2.9 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 OAP59891.1 - 0.0016 18.9 0.0 0.006 17.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Spc97_Spc98 PF04130.8 OAP59894.1 - 1.4e-122 409.8 1.6 2e-122 409.3 1.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family SoxD PF04267.7 OAP59894.1 - 0.24 11.2 1.5 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family Polysacc_deac_1 PF01522.16 OAP59896.1 - 3.6e-13 49.2 0.0 5.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Oxidored_FMN PF00724.15 OAP59897.1 - 8.7e-75 251.8 0.0 1.2e-74 251.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Polysacc_deac_1 PF01522.16 OAP59898.1 - 9.3e-10 38.1 0.0 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.16 OAP59899.1 - 1.7e-86 290.8 0.1 2.5e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Amidase Aa_trans PF01490.13 OAP59900.1 - 1.1e-23 83.4 30.0 1.4e-23 83.0 20.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 OAP59900.1 - 0.15 10.5 42.5 0.22 10.0 6.2 2.2 1 1 0 2 2 2 0 Amino acid permease Proteasome PF00227.21 OAP59901.1 - 5.7e-56 188.8 0.0 7.3e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAP59901.1 - 1e-13 50.3 0.2 2.3e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 OAP59901.1 - 0.021 14.5 0.1 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) TauD PF02668.11 OAP59902.1 - 3.7e-51 174.2 0.0 4.6e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 OAP59902.1 - 0.019 15.5 0.1 0.46 11.0 0.0 2.3 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily TMEMspv1-c74-12 PF11044.3 OAP59904.1 - 0.14 11.7 0.1 0.31 10.5 0.1 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Peptidase_M3 PF01432.15 OAP59905.1 - 1.2e-160 535.5 0.0 2.9e-160 534.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M3 DUF948 PF06103.6 OAP59905.1 - 0.054 13.3 0.1 0.27 11.1 0.1 2.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Arf PF00025.16 OAP59906.1 - 1.6e-72 242.4 0.0 1.8e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 OAP59906.1 - 3e-11 42.6 0.5 1.6e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 OAP59906.1 - 6.8e-11 41.7 0.0 8.4e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 OAP59906.1 - 1.6e-09 37.3 0.0 1.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP59906.1 - 4.5e-08 33.5 0.0 6.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 OAP59906.1 - 5.5e-08 32.2 0.0 6.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAP59906.1 - 2.1e-06 27.6 0.0 3.4e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAP59906.1 - 0.0038 16.6 0.0 0.45 9.9 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 OAP59906.1 - 0.013 14.3 0.6 0.099 11.3 0.1 2.4 2 1 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 OAP59906.1 - 0.036 13.3 0.3 0.15 11.3 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Actin PF00022.14 OAP59907.1 - 6.9e-30 103.7 0.0 4.6e-18 64.8 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 OAP59907.1 - 1.2e-06 27.3 0.0 0.00081 18.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 OAP59907.1 - 0.0039 16.1 0.2 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FtsA PF14450.1 OAP59907.1 - 0.082 12.7 0.1 0.18 11.6 0.1 1.8 1 1 0 1 1 1 0 Cell division protein FtsA Abhydrolase_6 PF12697.2 OAP59908.1 - 1.1e-27 97.3 0.0 2e-27 96.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP59908.1 - 4.9e-14 52.4 0.0 2.3e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP59908.1 - 1e-10 41.5 0.0 4.1e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 OAP59908.1 - 3.4e-05 22.4 0.0 5.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 OAP59908.1 - 0.0001 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Helicase_C PF00271.26 OAP59909.1 - 2.3e-13 49.7 0.0 4.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 OAP59909.1 - 3.5e-12 46.2 0.1 1.3e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 OAP59909.1 - 2.2e-08 33.7 0.1 9.2e-08 31.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 OAP59909.1 - 0.051 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 OAP59909.1 - 0.067 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain adh_short PF00106.20 OAP59910.1 - 4e-21 75.6 0.2 6.1e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP59910.1 - 3.2e-15 56.5 0.0 3.9e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP59910.1 - 0.0018 17.9 0.1 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 OAP59910.1 - 0.0025 17.3 0.2 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Phage_Mu_Gam PF07352.7 OAP59910.1 - 0.026 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein NAD_binding_10 PF13460.1 OAP59910.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 OAP59910.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Metallophos PF00149.23 OAP59912.1 - 9.2e-07 28.4 0.9 9.2e-07 28.4 0.6 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Transket_pyr PF02779.19 OAP59913.1 - 3.1e-49 166.8 0.0 4.7e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAP59913.1 - 9.8e-35 119.1 0.1 2.8e-34 117.7 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain LRR_4 PF12799.2 OAP59914.1 - 0.036 13.6 0.1 7.9 6.2 0.0 3.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF1691 PF07950.6 OAP59915.1 - 4.1e-31 107.1 1.9 1.7e-14 53.6 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 OAP59915.1 - 1.5 8.6 4.3 1.9 8.3 0.3 2.1 1 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF869 PF05911.6 OAP59916.1 - 0.06 11.5 27.1 0.11 10.7 1.0 2.4 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) Cytochrom_B562 PF07361.6 OAP59916.1 - 0.23 11.8 8.9 0.79 10.1 2.2 3.3 3 0 0 3 3 3 0 Cytochrome b562 CALCOCO1 PF07888.6 OAP59916.1 - 0.24 9.6 28.9 0.53 8.5 5.7 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Shugoshin_N PF07558.6 OAP59916.1 - 0.83 9.4 4.2 1.8 8.3 0.4 3.0 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region APG6 PF04111.7 OAP59916.1 - 2.3 7.2 39.9 0.047 12.7 3.1 4.1 2 2 2 4 4 4 0 Autophagy protein Apg6 RTBV_P46 PF06216.6 OAP59916.1 - 9.7 4.9 8.3 0.68 8.7 0.8 2.5 2 1 1 3 3 3 0 Rice tungro bacilliform virus P46 protein zf-C2H2_jaz PF12171.3 OAP59917.1 - 1.8e-05 24.7 3.5 3.1e-05 23.9 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP59917.1 - 0.0082 16.3 0.7 0.015 15.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Peptidase_M48 PF01435.13 OAP59917.1 - 0.07 12.6 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 zf-C2H2_4 PF13894.1 OAP59917.1 - 0.11 12.8 0.2 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP59917.1 - 0.19 12.1 1.0 0.36 11.2 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type IncA PF04156.9 OAP59917.1 - 0.34 10.4 1.3 0.47 10.0 0.9 1.2 1 0 0 1 1 1 0 IncA protein TRM PF02005.11 OAP59919.1 - 2.9e-105 352.2 0.0 2.3e-92 309.8 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 OAP59919.1 - 1.4e-06 28.0 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 OAP59919.1 - 0.008 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 OAP59919.1 - 0.017 15.6 0.0 0.049 14.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAP59919.1 - 0.051 13.1 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAP59919.1 - 0.068 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Gag_p12 PF01141.13 OAP59920.1 - 0.084 13.0 2.0 0.56 10.3 0.1 2.5 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Fe-S_biosyn PF01521.15 OAP59921.1 - 2.2e-10 40.4 0.1 1.5e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_5 PF00266.14 OAP59922.1 - 8.8e-08 31.2 0.0 3.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 OAP59922.1 - 0.07 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family F-box-like PF12937.2 OAP59923.1 - 0.0044 16.7 0.6 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 OAP59923.1 - 0.09 12.4 8.7 15 5.3 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Rad9 PF04139.8 OAP59924.1 - 7.4e-63 212.0 0.0 9.6e-63 211.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 OAP59924.1 - 1.2e-05 24.2 0.0 4.2e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RCC1 PF00415.13 OAP59925.1 - 1e-22 80.0 19.7 2.3e-07 30.9 0.7 7.3 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAP59925.1 - 2.3e-21 74.8 15.9 2.7e-05 23.6 1.1 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_3 PF00933.16 OAP59926.1 - 1.5e-84 283.5 0.0 2.2e-84 282.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAP59926.1 - 3.5e-67 226.2 0.0 7.6e-67 225.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 OAP59926.1 - 1.1e-23 82.9 1.0 2.4e-23 81.8 0.7 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 OAP59926.1 - 7.8e-10 38.5 0.0 1.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 PA14 domain Nucleo_P87 PF07267.6 OAP59927.1 - 0.011 14.4 2.0 0.012 14.3 1.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Bac_surface_Ag PF01103.18 OAP59929.1 - 7.3e-41 140.6 0.9 1.4e-40 139.7 0.7 1.5 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.12 OAP59929.1 - 0.00046 19.7 15.4 0.0028 17.1 10.7 2.0 1 1 0 1 1 1 1 Yip1 domain UQ_con PF00179.21 OAP59930.1 - 6.2e-25 87.2 0.0 8.4e-25 86.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAP59930.1 - 0.054 13.3 0.2 0.083 12.7 0.1 1.3 1 0 0 1 1 1 0 RWD domain DUF2631 PF10939.3 OAP59930.1 - 0.094 12.5 0.6 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) Fungal_trans_2 PF11951.3 OAP59931.1 - 2e-05 23.3 1.5 0.016 13.8 0.1 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.12 OAP59932.1 - 5.5e-77 258.8 0.1 7.2e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Paf1 PF03985.8 OAP59933.1 - 2.8e-36 125.1 1.4 4.5e-24 85.0 0.0 3.0 3 0 0 3 3 3 3 Paf1 Paf67 PF10255.4 OAP59934.1 - 9.3e-151 502.2 0.0 1.1e-150 502.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 OAP59934.1 - 0.029 14.2 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 OAP59934.1 - 0.044 13.5 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 CN_hydrolase PF00795.17 OAP59935.1 - 4.2e-22 78.3 0.0 5.6e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-MYND PF01753.13 OAP59937.1 - 8.6e-12 44.7 10.7 1.5e-11 43.9 7.4 1.4 1 0 0 1 1 1 1 MYND finger DUF805 PF05656.9 OAP59938.1 - 0.0063 16.3 4.1 0.019 14.8 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF805) Rhodanese PF00581.15 OAP59939.1 - 7.3e-09 35.9 0.1 5.5e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 Rhodanese-like domain Ribosomal_60s PF00428.14 OAP59939.1 - 0.053 13.9 1.9 0.082 13.3 1.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_S21 PF01165.15 OAP59940.1 - 1.4e-07 30.8 2.7 1.4e-07 30.8 1.8 1.9 2 0 0 2 2 2 1 Ribosomal protein S21 zf-C3HC4 PF00097.20 OAP59941.1 - 0.0013 18.3 1.8 0.0029 17.2 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP59941.1 - 0.0046 16.9 3.7 0.0086 16.0 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP59941.1 - 0.016 14.8 6.1 0.033 13.9 4.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAP59941.1 - 0.025 14.2 0.4 0.19 11.4 0.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger DASH_Dad2 PF08654.5 OAP59941.1 - 0.032 14.2 0.4 0.032 14.2 0.3 2.1 3 0 0 3 3 3 0 DASH complex subunit Dad2 zf-C3HC4_4 PF15227.1 OAP59941.1 - 0.038 13.8 0.7 0.087 12.7 0.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HAUS-augmin3 PF14932.1 OAP59941.1 - 0.054 12.6 1.7 0.088 11.9 1.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 zf-C3HC4_3 PF13920.1 OAP59941.1 - 0.055 13.1 5.6 0.094 12.3 3.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 OAP59941.1 - 0.073 12.8 2.6 0.16 11.7 1.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Filament PF00038.16 OAP59941.1 - 0.097 12.1 3.1 0.055 12.9 0.8 1.4 2 0 0 2 2 2 0 Intermediate filament protein DIL PF01843.14 OAP59941.1 - 0.11 12.3 1.0 0.27 11.1 0.7 1.6 1 0 0 1 1 1 0 DIL domain GLE1 PF07817.8 OAP59941.1 - 0.19 10.6 2.5 0.14 11.0 0.5 1.5 2 0 0 2 2 2 0 GLE1-like protein Vps51 PF08700.6 OAP59941.1 - 0.3 10.9 3.4 1.3 8.9 2.3 2.0 1 1 0 1 1 1 0 Vps51/Vps67 zf-RING_2 PF13639.1 OAP59941.1 - 0.38 10.6 3.8 0.8 9.5 2.6 1.6 1 0 0 1 1 1 0 Ring finger domain DUF4404 PF14357.1 OAP59941.1 - 5.3 7.5 6.5 3 8.3 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) FAD_binding_7 PF03441.9 OAP59942.1 - 9.4e-75 251.3 0.7 9.4e-75 251.3 0.5 1.4 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAP59942.1 - 4.7e-40 137.0 0.9 1.7e-39 135.2 0.0 2.1 2 1 1 3 3 3 1 DNA photolyase Usp PF00582.21 OAP59942.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Universal stress protein family Fungal_trans PF04082.13 OAP59943.1 - 3.3e-18 65.5 0.3 6.6e-18 64.5 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 OAP59943.1 - 7.6e-08 32.2 7.2 2.4e-06 27.5 0.7 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP59943.1 - 6.1e-06 26.2 11.7 0.0014 18.8 2.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP59943.1 - 0.00092 19.4 14.6 0.0067 16.7 3.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 OAP59943.1 - 0.042 13.9 4.0 0.079 13.0 2.8 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 OAP59943.1 - 0.44 10.7 3.1 16 5.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sugar_tr PF00083.19 OAP59944.1 - 3.3e-73 246.7 19.8 3.8e-73 246.5 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP59944.1 - 2.1e-24 85.8 41.1 1.4e-23 83.1 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ORC4_C PF14629.1 OAP59945.1 - 6.4e-31 107.3 0.0 1e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 OAP59945.1 - 5.6e-19 68.8 0.4 5.6e-19 68.8 0.3 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP59945.1 - 4.9e-07 29.9 0.0 1.5e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 OAP59945.1 - 3.6e-05 23.4 0.0 0.00013 21.6 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 OAP59945.1 - 6e-05 23.2 0.0 0.00031 20.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 OAP59945.1 - 7.1e-05 22.6 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 OAP59945.1 - 0.0021 17.0 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 OAP59945.1 - 0.021 13.8 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Mg_chelatase PF01078.16 OAP59945.1 - 0.028 13.5 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAP59945.1 - 0.039 13.6 0.0 0.77 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TPR_12 PF13424.1 OAP59947.1 - 7.4e-10 38.6 2.0 3.4e-06 26.9 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat Clr5 PF14420.1 OAP59947.1 - 4.4e-05 23.2 2.6 9.3e-05 22.2 1.8 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_11 PF13414.1 OAP59947.1 - 0.0023 17.5 1.0 0.11 12.1 0.1 3.0 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 OAP59947.1 - 0.0032 17.2 5.1 0.14 12.1 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP59947.1 - 0.0033 17.9 7.5 0.25 12.0 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAP59947.1 - 0.0034 17.2 4.9 21 5.2 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP59947.1 - 0.012 16.2 2.7 4.1 8.1 0.2 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP59947.1 - 0.027 14.2 4.4 0.11 12.3 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAP59947.1 - 0.031 14.0 0.1 3.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAP59947.1 - 0.21 12.0 10.9 2.7 8.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.11 OAP59948.1 - 6.6e-48 163.2 12.2 2e-42 145.1 4.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 OAP59948.1 - 0.0035 16.1 0.3 0.074 11.7 0.0 2.2 2 0 0 2 2 2 1 BT1 family OATP PF03137.15 OAP59948.1 - 0.0055 14.8 0.0 0.79 7.7 0.4 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF697 PF05128.7 OAP59948.1 - 0.54 9.7 4.0 0.71 9.3 1.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF697) PUCC PF03209.10 OAP59948.1 - 1.1 7.9 15.3 0.17 10.5 4.1 3.1 2 2 1 3 3 3 0 PUCC protein Pterin_bind PF00809.17 OAP59949.1 - 1.1e-62 211.1 0.0 2.2e-62 210.1 0.0 1.5 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 OAP59949.1 - 4.1e-42 142.8 0.0 9.9e-42 141.6 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 OAP59950.1 - 1.1e-69 235.1 0.5 1.3e-69 234.8 0.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAP59950.1 - 5.7e-09 35.3 0.0 1.7e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAP59950.1 - 1.4e-05 24.1 0.8 2.4e-05 23.3 0.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 OAP59950.1 - 0.00054 19.0 0.1 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 OAP59950.1 - 0.014 14.3 0.2 0.027 13.3 0.1 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase HSP70 PF00012.15 OAP59951.1 - 6.9e-16 57.2 0.0 1.3e-15 56.3 0.0 1.4 2 0 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.15 OAP59951.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family GAS PF13851.1 OAP59952.1 - 0.0019 17.4 3.3 0.0035 16.5 2.3 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 OAP59952.1 - 0.018 14.9 6.5 0.038 13.8 4.5 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 OAP59952.1 - 0.022 14.2 3.3 0.035 13.5 2.3 1.2 1 0 0 1 1 1 0 Intermediate filament protein CorA PF01544.13 OAP59952.1 - 0.15 11.0 0.5 0.25 10.3 0.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 OAP59952.1 - 0.2 11.2 6.0 0.34 10.4 4.2 1.3 1 0 0 1 1 1 0 IncA protein HAP1_N PF04849.8 OAP59952.1 - 0.27 10.1 7.6 0.1 11.5 3.0 1.8 2 1 1 3 3 3 0 HAP1 N-terminal conserved region DUF4404 PF14357.1 OAP59952.1 - 0.94 9.9 4.5 35 4.9 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) HALZ PF02183.13 OAP59952.1 - 1.4 8.7 5.6 0.42 10.3 0.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 OAP59952.1 - 4.7 6.7 7.4 2.1 7.9 1.9 2.3 1 1 1 2 2 2 0 Septum formation initiator eIF3g PF12353.3 OAP59953.1 - 9.6e-42 141.9 3.9 1.5e-41 141.2 2.7 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 OAP59953.1 - 2.8e-17 62.1 0.0 5.6e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP59953.1 - 4.8e-14 52.0 0.1 8.9e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP59953.1 - 5.1e-08 32.6 0.0 8.5e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.7 OAP59955.1 - 5.5e-36 124.3 0.0 8.1e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family GCV_T PF01571.16 OAP59956.1 - 2.2e-61 206.9 0.0 2.8e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 OAP59956.1 - 1.5e-19 69.8 0.1 2.3e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain CHD5 PF04420.9 OAP59957.1 - 6.1e-47 159.2 0.1 7.7e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 CHD5-like protein Adaptin_N PF01602.15 OAP59958.1 - 1.1e-131 439.7 10.3 1.4e-131 439.4 7.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAP59958.1 - 1.1e-17 64.4 3.8 5.2e-17 62.2 0.2 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 OAP59958.1 - 6.7e-16 58.3 5.0 8e-10 38.8 0.1 5.0 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 OAP59958.1 - 1.7e-10 40.0 5.0 0.033 14.2 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 OAP59958.1 - 9e-07 29.2 9.5 0.022 15.2 0.0 5.9 4 1 1 5 5 5 1 HEAT-like repeat Arm PF00514.18 OAP59958.1 - 3.2e-05 23.5 0.8 5.9 6.8 0.0 5.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 OAP59958.1 - 0.0019 17.6 1.9 2.9 7.1 0.0 3.8 2 1 0 3 3 3 2 CLASP N terminal Atx10homo_assoc PF09759.4 OAP59958.1 - 0.0039 16.9 0.0 1.6 8.4 0.0 3.5 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Lipoprotein_Ltp PF07553.6 OAP59958.1 - 0.084 12.7 0.2 0.55 10.1 0.0 2.4 3 0 0 3 3 3 0 Host cell surface-exposed lipoprotein FANCI_S2 PF14676.1 OAP59958.1 - 0.15 11.9 4.6 16 5.3 0.0 4.0 4 1 0 4 4 4 0 FANCI solenoid 2 DUF1077 PF06417.7 OAP59959.1 - 4.2e-53 178.0 0.7 4.9e-53 177.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) RPAP2_Rtr1 PF04181.8 OAP59960.1 - 3.7e-15 55.7 0.1 7.4e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_2 PF07653.12 OAP59961.1 - 8.5e-10 37.9 0.0 1.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAP59961.1 - 2.1e-09 36.5 0.1 6.2e-09 35.1 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAP59961.1 - 1.1e-08 34.5 0.1 2.7e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Nop14 PF04147.7 OAP59961.1 - 1.8 6.4 17.3 0.11 10.3 8.0 1.8 2 0 0 2 2 2 0 Nop14-like family CUE PF02845.11 OAP59962.1 - 6.9e-08 31.8 0.0 1.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain DAG1 PF05454.6 OAP59962.1 - 0.011 14.8 4.4 0.022 13.9 3.1 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) MitoNEET_N PF10660.4 OAP59962.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Sld5 PF05916.6 OAP59963.1 - 1.7e-27 95.8 0.0 2.7e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DIE2_ALG10 PF04922.7 OAP59964.1 - 3.4e-79 266.6 16.2 4.2e-79 266.3 11.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family AA_permease_2 PF13520.1 OAP59965.1 - 8.5e-47 159.6 49.6 3.6e-45 154.2 30.1 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 OAP59965.1 - 1.4e-22 79.7 36.3 1.4e-22 79.7 25.2 2.0 2 0 0 2 2 2 1 Amino acid permease DUF2235 PF09994.4 OAP59966.1 - 2.3e-35 122.3 0.0 5.5e-34 117.7 0.0 2.5 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fis1_TPR_C PF14853.1 OAP59968.1 - 0.11 12.3 0.1 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat 4HB_MCP_1 PF12729.2 OAP59968.1 - 0.17 11.2 0.2 0.24 10.7 0.2 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction RRM_1 PF00076.17 OAP59969.1 - 8e-10 38.2 0.0 1.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP59969.1 - 1.2e-06 28.4 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAP59969.1 - 8.2e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 OAP59969.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Alkyl_sulf_dimr PF14863.1 OAP59973.1 - 2.7 8.1 7.4 0.4 10.9 2.1 1.7 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation APH PF01636.18 OAP59974.1 - 1e-13 51.6 0.1 1.3e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAP59974.1 - 3.1e-05 23.2 0.0 8.7e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 OAP59974.1 - 0.00066 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF2458 PF10454.4 OAP59977.1 - 4.9e-35 120.6 0.0 4.9e-35 120.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) COX14 PF14880.1 OAP59978.1 - 2.3e-11 43.1 0.1 2.3e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DAHP_synth_1 PF00793.15 OAP59980.1 - 3.8e-95 317.6 0.1 4.7e-95 317.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family FAT PF02259.18 OAP59981.1 - 2.1e-114 382.1 0.9 6.4e-114 380.5 0.6 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 OAP59981.1 - 9.8e-60 201.9 0.7 2e-59 200.9 0.5 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 OAP59981.1 - 7.1e-55 185.3 0.7 1.1e-53 181.4 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 OAP59981.1 - 7.3e-40 135.1 1.2 6.9e-39 131.9 0.0 3.1 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 OAP59981.1 - 2.7e-21 75.6 14.3 9.3e-06 25.8 0.0 9.0 6 2 3 9 9 9 6 HEAT repeats FATC PF02260.15 OAP59981.1 - 4e-16 58.1 0.2 1.6e-15 56.1 0.1 2.2 2 0 0 2 2 2 1 FATC domain HEAT PF02985.17 OAP59981.1 - 5.9e-13 47.7 19.0 1.4 9.2 0.0 12.0 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 OAP59981.1 - 7.7e-10 38.9 20.1 0.93 10.0 0.0 12.5 9 3 5 14 14 14 3 HEAT-like repeat TPR_19 PF14559.1 OAP59981.1 - 0.06 13.6 7.9 0.94 9.8 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP59981.1 - 0.67 10.7 0.0 0.67 10.7 0.0 6.3 9 0 0 9 9 9 0 Tetratricopeptide repeat PAP_assoc PF03828.14 OAP59982.1 - 3.6e-10 39.6 0.0 7.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 OAP59982.1 - 2.9e-06 27.5 0.0 6.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Zn_clus PF00172.13 OAP59983.1 - 1.6e-07 31.0 10.5 2.9e-07 30.2 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP59983.1 - 2.5e-07 29.6 0.0 4.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ndc1_Nup PF09531.5 OAP59983.1 - 9.1 4.5 7.1 14 3.9 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING_2 PF13639.1 OAP59985.1 - 4.7e-06 26.3 0.6 8.3e-06 25.5 0.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAP59985.1 - 0.41 10.3 0.6 0.72 9.5 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_pol_I_TF PF04090.7 OAP59986.1 - 1.1e-05 24.8 0.0 7.9e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor Cut8_N PF14482.1 OAP59986.1 - 2.1 8.4 5.0 0.53 10.3 0.1 2.4 3 0 0 3 3 3 0 Cut8 proteasome-binding domain DUF3419 PF11899.3 OAP59987.1 - 8.6e-148 492.0 0.1 1.3e-147 491.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 OAP59987.1 - 7.5e-11 41.8 0.0 2.2e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP59987.1 - 3e-09 37.2 0.0 2.1e-07 31.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP59987.1 - 4.2e-09 36.7 0.0 5.1e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP59987.1 - 1.3e-08 34.7 0.0 1.9e-07 30.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP59987.1 - 2.2e-08 33.5 0.0 4.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 OAP59987.1 - 5.2e-07 29.4 0.0 8.8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 OAP59987.1 - 7.2e-07 29.7 0.0 2.5e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP59987.1 - 2.6e-06 27.4 0.0 7.9e-05 22.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP59987.1 - 8.4e-06 26.0 0.0 2.7e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Rsm22 PF09243.5 OAP59987.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 ADP_ribosyl_GH PF03747.9 OAP59989.1 - 2.9e-69 234.0 0.0 3.4e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Yip1 PF04893.12 OAP59990.1 - 8.4e-15 54.6 9.6 1.3e-14 54.0 6.7 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 OAP59990.1 - 0.28 10.8 7.5 0.48 10.0 5.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Ran_BP1 PF00638.13 OAP59991.1 - 6e-16 58.6 0.0 7.4e-10 38.9 0.1 2.4 2 0 0 2 2 2 2 RanBP1 domain Zn_Tnp_IS91 PF14319.1 OAP59992.1 - 0.026 14.0 0.1 0.026 14.0 0.1 2.0 2 0 0 2 2 2 0 Transposase zinc-binding domain RWD PF05773.17 OAP59994.1 - 5.4e-06 26.2 0.0 2.1e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 RWD domain Amidohydro_2 PF04909.9 OAP59995.1 - 2.7e-34 119.0 0.3 3.4e-34 118.6 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 OAP59996.1 - 4.1e-16 58.6 0.4 7.7e-16 57.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP59996.1 - 5e-10 39.1 9.0 1.1e-09 38.0 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 OAP59997.1 - 1.8e-22 79.8 0.0 2.7e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP59997.1 - 3.5e-07 29.4 11.7 0.0015 17.5 3.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP59997.1 - 2.8e-05 24.0 1.9 8.6e-05 22.4 1.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP59997.1 - 4.3e-05 22.5 5.4 5.6e-05 22.1 2.1 2.0 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 OAP59997.1 - 8.8e-05 21.2 6.2 0.0025 16.5 0.6 2.1 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 OAP59997.1 - 0.00087 17.8 3.6 0.0039 15.7 1.4 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 OAP59997.1 - 0.00092 19.5 2.4 0.033 14.5 0.8 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP59997.1 - 0.0024 17.0 1.8 0.0035 16.4 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP59997.1 - 0.0043 16.9 1.3 0.0079 16.0 0.9 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP59997.1 - 0.011 14.7 4.0 0.024 13.5 2.8 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP59997.1 - 0.011 15.8 0.3 0.029 14.4 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 OAP59997.1 - 0.026 13.3 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.13 OAP59997.1 - 0.033 13.8 0.2 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 OAP59997.1 - 0.37 9.5 2.2 0.54 9.0 1.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Transp_cyt_pur PF02133.10 OAP59998.1 - 1.2e-20 73.4 32.9 1.8e-20 72.9 22.8 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 OAP59999.1 - 5.6e-16 58.1 2.8 5.6e-16 58.1 1.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 OAP60001.1 - 3.6e-30 104.7 0.0 8.6e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60001.1 - 2.5e-08 33.6 7.3 4.1e-08 32.9 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2339 PF10101.4 OAP60001.1 - 0.33 9.1 1.0 0.49 8.6 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) AAA PF00004.24 OAP60002.1 - 5.5e-37 126.9 0.0 1.3e-36 125.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAP60002.1 - 5.1e-06 26.6 2.2 0.0006 19.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 OAP60002.1 - 9.3e-06 25.5 0.0 2.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP60002.1 - 2.6e-05 24.3 0.1 0.00079 19.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAP60002.1 - 3e-05 23.1 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 OAP60002.1 - 4.7e-05 23.1 0.1 0.00034 20.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 OAP60002.1 - 0.00016 22.4 0.1 0.00067 20.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 OAP60002.1 - 0.00022 20.6 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 OAP60002.1 - 0.00023 21.0 0.0 0.0006 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 OAP60002.1 - 0.00061 19.7 0.3 0.0086 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAP60002.1 - 0.00063 19.8 0.1 0.0019 18.2 0.0 1.8 2 0 0 2 2 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 OAP60002.1 - 0.00073 18.7 0.1 0.0014 17.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 OAP60002.1 - 0.0018 18.4 0.0 0.0058 16.7 0.0 1.9 2 1 0 2 2 1 1 RNA helicase NACHT PF05729.7 OAP60002.1 - 0.0022 17.6 0.1 0.01 15.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_2 PF07724.9 OAP60002.1 - 0.0025 17.7 0.0 0.0072 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 OAP60002.1 - 0.0027 18.0 0.0 0.018 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAP60002.1 - 0.0036 17.0 0.3 0.02 14.6 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 OAP60002.1 - 0.0039 16.6 6.2 0.025 13.9 0.1 3.1 3 1 0 4 4 3 1 AAA domain Zeta_toxin PF06414.7 OAP60002.1 - 0.0049 15.9 0.0 0.0092 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 OAP60002.1 - 0.0064 15.4 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 OAP60002.1 - 0.0073 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 OAP60002.1 - 0.0074 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 OAP60002.1 - 0.013 15.1 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein Guanylate_kin PF00625.16 OAP60002.1 - 0.019 14.3 0.0 0.2 11.0 0.0 2.6 3 0 0 3 3 3 0 Guanylate kinase Parvo_NS1 PF01057.12 OAP60002.1 - 0.021 13.6 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 OAP60002.1 - 0.027 14.1 0.1 0.27 10.9 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 OAP60002.1 - 0.031 13.7 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 OAP60002.1 - 0.043 14.1 0.3 0.14 12.4 0.0 2.0 2 0 0 2 2 1 0 ABC transporter NB-ARC PF00931.17 OAP60002.1 - 0.077 11.8 0.0 0.18 10.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.13 OAP60002.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 OAP60002.1 - 0.094 11.4 0.1 0.22 10.1 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus Rad17 PF03215.10 OAP60002.1 - 0.095 11.3 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CPT PF07931.7 OAP60002.1 - 0.095 12.3 0.2 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.17 OAP60002.1 - 0.098 12.5 0.2 0.32 10.8 0.0 2.0 2 0 0 2 2 1 0 Shikimate kinase Csm1 PF12539.3 OAP60003.1 - 2.6e-24 85.5 0.2 4.9e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Cep57_CLD PF14073.1 OAP60003.1 - 0.0025 17.6 5.8 0.0088 15.8 4.0 1.9 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 NYD-SP28 PF14772.1 OAP60003.1 - 0.0042 17.1 4.0 0.0042 17.1 2.8 2.8 2 1 1 3 3 3 1 Sperm tail APG6 PF04111.7 OAP60003.1 - 0.0058 15.7 5.9 0.013 14.5 4.1 1.5 1 0 0 1 1 1 1 Autophagy protein Apg6 Reo_sigmaC PF04582.7 OAP60003.1 - 0.0077 15.4 1.0 0.013 14.6 0.7 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Atg14 PF10186.4 OAP60003.1 - 0.037 12.9 5.1 0.1 11.5 3.5 1.8 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FANCI_S4 PF14678.1 OAP60003.1 - 0.038 13.0 0.6 0.071 12.1 0.4 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 CheZ PF04344.8 OAP60003.1 - 0.12 12.0 6.4 0.13 11.9 2.7 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ GAS PF13851.1 OAP60003.1 - 0.36 10.0 9.9 0.86 8.7 5.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding THOC7 PF05615.8 OAP60003.1 - 0.38 11.0 7.7 0.7 10.1 3.7 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 TMF_DNA_bd PF12329.3 OAP60003.1 - 1.7 8.5 12.3 0.66 9.8 3.1 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 OAP60003.1 - 2.2 8.1 17.6 0.071 13.0 5.8 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding HR1 PF02185.11 OAP60003.1 - 3 7.6 11.6 1.5 8.5 0.7 2.7 1 1 1 2 2 2 0 Hr1 repeat adh_short PF00106.20 OAP60005.1 - 5.3e-13 49.2 2.7 3.6e-11 43.2 1.9 2.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60005.1 - 1e-05 25.4 0.0 1.6e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 OAP60005.1 - 6.8e-05 22.1 0.0 8.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 OAP60005.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Retinal PF15449.1 OAP60005.1 - 0.068 10.8 0.6 0.09 10.4 0.4 1.0 1 0 0 1 1 1 0 Retinal protein MTP18 PF10558.4 OAP60007.1 - 3e-68 228.3 0.1 3.9e-68 228.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2611 PF11022.3 OAP60008.1 - 1.3e-28 98.8 0.0 1.4e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Peroxin-13_N PF04088.8 OAP60008.1 - 0.091 12.7 0.5 0.69 9.8 0.0 1.9 2 0 0 2 2 2 0 Peroxin 13, N-terminal region AAT PF03417.11 OAP60009.1 - 6.9e-30 104.1 0.0 8.7e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 OAP60009.1 - 3e-05 24.2 0.0 0.00011 22.4 0.0 1.9 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ACPS PF01648.15 OAP60010.1 - 1e-13 51.1 0.1 1.8e-13 50.2 0.1 1.4 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Rossmann-like PF10727.4 OAP60010.1 - 0.042 13.5 0.1 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 Rossmann-like domain Methyltransf_3 PF01596.12 OAP60011.1 - 1.4e-28 99.3 0.0 1e-21 76.9 0.0 2.0 1 1 1 2 2 2 2 O-methyltransferase Methyltransf_24 PF13578.1 OAP60011.1 - 1.8e-09 38.3 0.0 4e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP60011.1 - 0.0012 19.4 0.1 0.0074 16.8 0.0 2.2 2 1 1 3 3 3 1 Methyltransferase domain Thioredoxin_2 PF13098.1 OAP60012.1 - 0.0031 17.7 0.1 0.0032 17.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain NACHT PF05729.7 OAP60013.1 - 2.1e-08 34.0 0.1 7.4e-08 32.2 0.1 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 OAP60013.1 - 0.0005 20.2 0.2 0.0035 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAP60013.1 - 0.009 15.4 0.4 0.039 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 OAP60013.1 - 0.033 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 OAP60013.1 - 0.041 14.2 0.0 0.041 14.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 OAP60013.1 - 0.069 13.9 0.2 0.61 10.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 OAP60013.1 - 0.09 12.2 0.0 0.7 9.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Lipoxygenase PF00305.14 OAP60015.1 - 1.6e-31 109.0 0.1 2.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase EthD PF07110.6 OAP60016.1 - 1.2e-14 55.0 0.5 1.5e-14 54.7 0.4 1.1 1 0 0 1 1 1 1 EthD domain adh_short PF00106.20 OAP60017.1 - 6.4e-23 81.4 0.0 2.5e-22 79.5 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60017.1 - 3.3e-10 40.1 0.0 1.1e-09 38.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP60017.1 - 2.8e-06 27.1 0.0 2.2e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 OAP60017.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP60017.1 - 0.018 13.7 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 OAP60018.1 - 3.3e-24 85.2 35.1 3.3e-24 85.2 24.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ABM PF03992.11 OAP60019.1 - 9.1e-09 35.2 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PigN PF04987.9 OAP60021.1 - 3.7e-160 533.4 34.6 4.9e-160 533.0 24.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 OAP60021.1 - 6.4e-09 35.6 1.0 2.1e-07 30.5 0.8 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 OAP60021.1 - 1.4e-07 31.0 0.1 2.1e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 OAP60021.1 - 2.2e-05 23.9 0.3 0.00011 21.6 0.0 2.0 2 0 0 2 2 2 1 Metalloenzyme superfamily EAP30 PF04157.11 OAP60022.1 - 1e-49 168.7 0.0 1.2e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family SAC3_GANP PF03399.11 OAP60023.1 - 2.6e-57 193.7 1.5 4e-35 121.2 0.2 2.3 1 1 1 2 2 2 2 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 OAP60023.1 - 7.9e-07 28.9 0.0 1.9e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 OAP60024.1 - 2.4e-23 81.2 0.1 3e-10 39.3 0.0 3.3 4 0 0 4 4 4 2 SH3 domain SH3_9 PF14604.1 OAP60024.1 - 6.6e-14 51.2 2.8 4.8e-07 29.2 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 OAP60024.1 - 3.1e-12 46.2 0.0 7.2e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 OAP60024.1 - 2.2e-09 36.6 0.0 5.2e-06 25.8 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 OAP60024.1 - 5.5e-09 35.5 0.4 1e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 PB1 domain AP2 PF00847.15 OAP60024.1 - 0.0023 18.0 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 AP2 domain AFG1_ATPase PF03969.11 OAP60025.1 - 1e-96 323.9 0.0 2.2e-91 306.3 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 OAP60025.1 - 4.8e-06 26.6 5.5 0.39 10.6 0.5 3.6 3 1 0 4 4 4 3 AAA ATPase domain Bac_DnaA PF00308.13 OAP60025.1 - 0.0018 17.9 0.2 0.7 9.4 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.1 OAP60025.1 - 0.0023 17.8 0.0 0.0077 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 OAP60025.1 - 0.0031 16.3 0.1 0.38 9.5 0.1 2.3 2 0 0 2 2 2 2 MCM2/3/5 family AAA_22 PF13401.1 OAP60025.1 - 0.004 17.2 0.1 0.036 14.2 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 OAP60025.1 - 0.015 15.0 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 OAP60025.1 - 0.029 14.5 1.9 0.087 13.0 0.0 2.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 OAP60025.1 - 0.12 12.5 0.0 0.46 10.6 0.0 2.0 1 1 0 1 1 1 0 RNA helicase LysM PF01476.15 OAP60026.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 LysM domain Mitofilin PF09731.4 OAP60027.1 - 3.2 6.3 7.5 4.8 5.7 5.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cys_Met_Meta_PP PF01053.15 OAP60028.1 - 4.1e-137 456.5 0.0 4.9e-137 456.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAP60028.1 - 1.1e-06 27.9 0.0 1.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAP60028.1 - 2.2e-05 23.3 0.0 3.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 OAP60028.1 - 8.8e-05 21.6 0.1 0.00018 20.6 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 OAP60028.1 - 0.00065 18.5 0.0 0.00095 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 OAP60028.1 - 0.025 13.7 0.0 0.069 12.2 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase PHP PF02811.14 OAP60029.1 - 2.8e-10 40.2 0.0 7.6e-10 38.8 0.0 1.7 1 1 0 1 1 1 1 PHP domain FKBP_C PF00254.23 OAP60030.1 - 3.1e-13 49.5 0.0 4.2e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PRK PF00485.13 OAP60031.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 OAP60031.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.9 OAP60031.1 - 0.082 11.8 0.0 0.15 11.0 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain adh_short PF00106.20 OAP60032.1 - 1.3e-60 204.1 6.3 1.3e-30 106.4 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 OAP60032.1 - 8.7e-29 99.4 0.0 2.3e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 OAP60032.1 - 2.9e-28 98.7 1.5 3.6e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 OAP60032.1 - 0.001 18.1 0.8 0.0068 15.4 0.2 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 OAP60032.1 - 0.0036 16.7 3.9 0.049 13.0 0.1 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAP60032.1 - 0.67 9.5 6.3 3.8 7.1 0.8 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IBR PF01485.16 OAP60033.1 - 8.4e-07 28.7 3.7 8.4e-07 28.7 2.5 4.4 4 2 1 5 5 5 2 IBR domain DUF1444 PF07285.6 OAP60033.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) Aldo_ket_red PF00248.16 OAP60034.1 - 1.9e-57 194.2 0.0 2.5e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Bclx_interact PF08945.5 OAP60034.1 - 0.085 12.4 0.7 0.23 11.0 0.5 1.7 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Pam16 PF03656.8 OAP60035.1 - 3.1e-32 111.0 0.6 3.7e-32 110.7 0.4 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.6 OAP60036.1 - 3.3e-94 315.6 0.1 4.6e-94 315.1 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Chlorosome_CsmC PF11098.3 OAP60037.1 - 0.17 11.6 8.2 0.24 11.0 5.7 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C SseC PF04888.7 OAP60037.1 - 0.2 10.9 2.7 0.23 10.7 1.9 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Glycoprotein_B PF00606.13 OAP60037.1 - 0.21 9.5 1.3 0.21 9.5 0.9 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Lipase_3 PF01764.20 OAP60038.1 - 3.7e-05 23.3 0.0 7.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAP60038.1 - 0.0043 16.8 0.0 0.018 14.7 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family VPS9 PF02204.13 OAP60039.1 - 3.1e-24 85.0 0.0 5.3e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain KdpC PF02669.10 OAP60039.1 - 3.2 7.4 6.4 15 5.2 0.0 3.6 4 0 0 4 4 4 0 K+-transporting ATPase, c chain ECM11 PF15463.1 OAP60040.1 - 5.1e-24 85.1 0.2 5.1e-24 85.1 0.2 2.9 3 0 0 3 3 3 1 Extracellular mutant protein 11 PAS_3 PF08447.6 OAP60041.1 - 8.6e-14 51.4 0.0 1.8e-10 40.7 0.1 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 OAP60041.1 - 2.2e-11 44.0 0.0 1.2e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 OAP60041.1 - 1.2e-06 28.4 0.0 0.0003 20.7 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 OAP60041.1 - 5.3e-06 26.1 0.0 0.0028 17.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 OAP60041.1 - 5.2e-05 23.2 0.0 0.0071 16.3 0.0 3.0 3 0 0 3 3 3 1 PAS fold Bac_luciferase PF00296.15 OAP60042.1 - 4.4e-61 206.6 0.4 7e-61 206.0 0.3 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.7 OAP60043.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Pyr_redox_3 PF13738.1 OAP60044.1 - 5.3e-22 78.8 0.0 1.7e-21 77.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP60044.1 - 5.9e-15 54.4 0.0 1.5e-14 53.1 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP60044.1 - 2e-09 37.3 0.0 7.3e-09 35.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP60044.1 - 1.1e-06 27.7 0.2 3.8e-05 22.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP60044.1 - 9.1e-05 22.4 0.0 0.00078 19.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP60044.1 - 0.003 17.3 0.0 0.3 10.8 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 OAP60044.1 - 0.0094 14.8 0.0 2.7 6.7 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 OAP60044.1 - 0.026 13.6 0.1 0.082 11.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 OAP60044.1 - 0.039 12.1 0.6 4.5 5.3 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.9 OAP60044.1 - 0.61 8.4 1.3 1.2 7.5 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 OAP60045.1 - 2.3e-29 102.2 33.6 6.6e-29 100.7 23.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CreD PF06123.7 OAP60045.1 - 0.14 10.6 2.5 0.22 10.0 1.7 1.2 1 0 0 1 1 1 0 Inner membrane protein CreD Bac_luciferase PF00296.15 OAP60046.1 - 4.4e-61 206.6 0.1 6.4e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 OAP60047.1 - 3.3e-30 104.9 23.8 3.3e-30 104.9 16.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1614 PF07758.6 OAP60047.1 - 2.2 7.9 8.1 0.29 10.8 2.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1614) BPL_N PF09825.4 OAP60048.1 - 5e-135 450.0 5.9 4.9e-133 443.4 4.1 2.1 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 OAP60048.1 - 2.7e-18 66.1 0.0 5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 OAP60048.1 - 0.00019 21.0 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain CHCH PF06747.8 OAP60049.1 - 7.4e-07 28.9 8.9 1.2e-06 28.2 6.2 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 OAP60049.1 - 0.037 14.0 3.6 0.055 13.5 2.5 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 OAP60049.1 - 0.12 12.1 7.3 0.33 10.7 0.7 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Toxin_25 PF08095.6 OAP60049.1 - 0.29 10.9 0.4 0.29 10.9 0.2 2.2 2 0 0 2 2 2 0 Hefutoxin family Mgm101p PF06420.7 OAP60050.1 - 2e-89 297.3 0.0 2.5e-89 297.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Usp PF00582.21 OAP60051.1 - 2.7e-18 66.5 0.0 8.8e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Universal stress protein family ABA_GPCR PF12430.3 OAP60052.1 - 4.4e-48 163.0 2.8 4.4e-48 163.0 2.0 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 OAP60052.1 - 5.2e-19 68.0 0.7 2.8e-18 65.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) MitoNEET_N PF10660.4 OAP60052.1 - 0.027 14.3 0.1 0.099 12.5 0.1 2.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Syntaxin-18_N PF10496.4 OAP60053.1 - 2.4e-12 46.5 0.3 9.8e-12 44.5 0.1 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 OAP60053.1 - 5.8e-08 32.2 2.3 5.8e-08 32.2 1.6 2.8 3 0 0 3 3 3 1 SNARE domain DUF1043 PF06295.7 OAP60053.1 - 0.68 9.5 3.4 1.2 8.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) DUF948 PF06103.6 OAP60053.1 - 1.1 9.1 4.3 12 5.8 0.2 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Aminotran_1_2 PF00155.16 OAP60054.1 - 1.3e-83 280.9 0.0 1.5e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Acetyltransf_7 PF13508.1 OAP60055.1 - 0.089 12.9 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Neur_chan_memb PF02932.11 OAP60056.1 - 3.6 7.4 5.1 4.5 7.0 3.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 OAP60056.1 - 4.5 5.3 10.5 5.1 5.2 7.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hex_IIIa PF02455.11 OAP60056.1 - 8.7 4.9 7.6 9.7 4.7 5.2 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MS_channel PF00924.13 OAP60057.1 - 4.3e-20 71.9 0.8 7.4e-20 71.1 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 OAP60057.1 - 0.0063 15.7 0.3 0.018 14.2 0.2 1.9 1 0 0 1 1 1 1 EF hand Mcm10 PF09332.6 OAP60057.1 - 0.047 13.0 0.3 0.11 11.7 0.2 1.6 1 0 0 1 1 1 0 Mcm10 replication factor EF-hand_5 PF13202.1 OAP60057.1 - 0.064 12.6 0.0 0.2 11.0 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 OAP60057.1 - 0.066 13.3 0.3 0.2 11.7 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 OAP60057.1 - 0.12 12.0 0.9 0.34 10.5 0.6 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 OAP60057.1 - 0.19 11.7 0.5 2.3 8.3 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Serglycin PF04360.7 OAP60058.1 - 0.0082 15.8 7.5 0.014 15.0 5.2 1.5 1 0 0 1 1 1 1 Serglycin Orbi_VP6 PF01516.11 OAP60058.1 - 4.9 6.1 10.6 6.8 5.6 7.4 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF1654 PF07867.6 OAP60059.1 - 0.11 11.8 0.9 2.1 7.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Med12 PF09497.5 OAP60061.1 - 1.4e-24 85.8 0.1 3.6e-24 84.5 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Zn_clus PF00172.13 OAP60063.1 - 3.9e-08 33.0 10.3 6.5e-08 32.3 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP60063.1 - 8.6e-07 27.8 1.6 1.5e-06 27.1 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 OAP60064.1 - 2.9e-45 154.4 0.4 3.9e-45 154.0 0.3 1.1 1 0 0 1 1 1 1 RTA1 like protein GST_N_3 PF13417.1 OAP60065.1 - 1.2e-13 51.0 0.0 2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP60065.1 - 2e-10 40.6 0.0 3.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP60065.1 - 7e-10 38.7 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP60065.1 - 1.4e-08 34.6 0.0 2.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP60065.1 - 5.7e-06 26.7 0.0 9.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAP60065.1 - 1.3e-05 24.9 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cupin_2 PF07883.6 OAP60066.1 - 1.7e-25 88.2 0.0 7.8e-13 47.7 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 OAP60066.1 - 1.6e-06 27.8 0.0 0.005 16.5 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.3 OAP60066.1 - 2.4e-05 24.1 0.0 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Mif2/CENP-C like ARD PF03079.9 OAP60066.1 - 0.0019 18.1 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 2 ARD/ARD' family Cupin_3 PF05899.7 OAP60066.1 - 0.0025 17.1 0.0 1.4 8.3 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF861) DUF4437 PF14499.1 OAP60066.1 - 0.0029 16.5 0.1 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) Cupin_1 PF00190.17 OAP60066.1 - 0.05 13.0 0.0 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Cupin Aldedh PF00171.17 OAP60067.1 - 2.5e-127 425.0 0.1 2.8e-127 424.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 OAP60068.1 - 6.2e-36 123.6 0.0 1e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.1 OAP60068.1 - 0.077 12.9 0.8 0.2 11.6 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 OAP60069.1 - 8.2e-166 552.1 0.0 2.9e-165 550.3 0.0 1.9 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 OAP60069.1 - 1e-42 142.5 10.5 7.6e-10 38.3 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 OAP60069.1 - 4.1e-06 25.2 1.7 0.027 12.6 0.0 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Guanylate_cyc PF00211.15 OAP60070.1 - 1.5e-20 73.3 0.0 7.9e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Aconitase PF00330.15 OAP60071.1 - 4.1e-185 615.7 0.1 4.8e-185 615.4 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAP60071.1 - 2.8e-45 153.6 0.0 5.8e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RGS PF00615.14 OAP60072.1 - 3.1e-29 101.4 0.3 1.3e-28 99.4 0.1 2.1 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 OAP60072.1 - 4.4e-21 74.4 0.0 2.9e-17 62.1 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73 PF05179.9 OAP60073.1 - 2.5e-45 154.9 0.1 8.2e-44 150.0 0.1 2.4 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family OsmC PF02566.14 OAP60075.1 - 1.5e-17 63.5 0.0 2.3e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein MFS_1 PF07690.11 OAP60076.1 - 3.4e-11 42.4 43.3 3.4e-11 42.4 30.0 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily G-alpha PF00503.15 OAP60077.1 - 1.4e-40 139.2 0.4 2.1e-40 138.6 0.3 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Glutaredoxin PF00462.19 OAP60078.1 - 8.7e-19 67.2 0.0 1.8e-16 59.8 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.15 OAP60078.1 - 9.5e-14 50.9 0.0 3.9e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 OAP60078.1 - 0.0038 17.2 0.0 0.17 12.0 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like DUF834 PF05754.9 OAP60078.1 - 0.14 11.9 2.6 0.67 9.7 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF834) TauD PF02668.11 OAP60079.1 - 2.7e-37 128.8 0.1 1.4e-28 100.2 0.2 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.27 OAP60080.1 - 1.5e-14 53.1 2.3 0.14 12.1 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat NTR2 PF15458.1 OAP60081.1 - 1.6e-60 204.4 10.0 2.3e-60 203.9 7.0 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 ERM PF00769.14 OAP60081.1 - 0.031 13.8 6.8 0.19 11.2 0.3 2.7 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Acetyltransf_3 PF13302.1 OAP60082.1 - 1.3e-16 61.0 0.0 1.9e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP60082.1 - 0.0045 16.9 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family p450 PF00067.17 OAP60083.1 - 5.7e-58 196.5 0.0 7.4e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LSM PF01423.17 OAP60084.1 - 3e-18 65.1 0.5 3.4e-18 64.9 0.4 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1 PF01433.15 OAP60085.1 - 2.7e-08 33.3 0.0 0.011 14.8 0.0 3.3 2 1 1 3 3 3 3 Peptidase family M1 CDP-OH_P_transf PF01066.16 OAP60086.1 - 2.5e-13 50.1 12.3 2.5e-13 50.1 8.5 3.0 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HpcH_HpaI PF03328.9 OAP60087.1 - 5.5e-41 139.8 0.0 7.7e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 OAP60087.1 - 2.1e-14 53.1 0.1 3.4e-09 35.9 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Pkinase PF00069.20 OAP60088.1 - 1.3e-70 237.5 0.0 1.8e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP60088.1 - 1.5e-32 112.6 0.0 2.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAP60088.1 - 4.1e-09 36.8 0.2 1.2e-08 35.2 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAP60088.1 - 0.00024 20.1 0.0 0.00039 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SWIRM PF04433.12 OAP60089.1 - 1.6e-13 50.5 0.0 4.7e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 OAP60089.1 - 3.1e-10 39.4 5.4 5.6e-10 38.5 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 OAP60089.1 - 2.3e-06 27.5 0.0 6.5e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF737 PF05300.6 OAP60090.1 - 0.029 14.3 7.5 0.037 14.0 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ATP-synt_B PF00430.13 OAP60090.1 - 1.6 8.5 10.0 2.4 7.9 6.9 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) GDC-P PF02347.11 OAP60091.1 - 3.9e-178 592.5 0.0 5.6e-163 542.5 0.0 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 OAP60091.1 - 1.4e-08 34.2 0.0 3.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 OAP60091.1 - 7.2e-07 28.2 0.2 0.00012 20.9 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 OAP60091.1 - 0.018 13.4 0.1 0.083 11.3 0.0 2.1 3 0 0 3 3 3 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Cys_Met_Meta_PP PF01053.15 OAP60091.1 - 0.043 12.0 0.2 0.47 8.6 0.1 2.1 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme zf-C4_ClpX PF06689.8 OAP60091.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 ClpX C4-type zinc finger Senescence PF06911.7 OAP60092.1 - 0.013 15.1 2.8 0.019 14.6 2.0 1.2 1 0 0 1 1 1 0 Senescence-associated protein SseC PF04888.7 OAP60092.1 - 0.57 9.4 2.6 0.67 9.2 1.8 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Sporozoite_P67 PF05642.6 OAP60094.1 - 2.6 5.8 10.7 3 5.5 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Arylsulfotran_2 PF14269.1 OAP60095.1 - 6.2e-51 173.3 2.3 9e-51 172.7 1.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAP60095.1 - 3.4e-21 75.3 0.5 6.8e-21 74.3 0.3 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) F-box PF00646.28 OAP60096.1 - 0.00027 20.5 0.2 0.00075 19.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP60096.1 - 0.003 17.2 0.6 0.019 14.7 0.2 2.4 2 0 0 2 2 2 1 F-box-like UFD1 PF03152.9 OAP60097.1 - 1.6e-25 89.2 0.0 3.2e-22 78.4 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zf-TFIIB PF13453.1 OAP60097.1 - 0.11 11.7 2.3 0.68 9.1 0.0 2.9 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-ribbon_3 PF13248.1 OAP60097.1 - 3.6 6.9 6.9 16 4.8 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Ring_hydroxyl_A PF00848.14 OAP60099.1 - 3.4e-35 121.6 2.3 5.6e-35 120.9 1.6 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 OAP60099.1 - 5.2e-15 54.7 0.1 9.8e-15 53.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans_2 PF11951.3 OAP60100.1 - 8.5e-37 126.6 0.1 5.3e-36 124.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60100.1 - 0.00012 21.9 9.2 0.00012 21.9 6.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 OAP60101.1 - 2.6e-25 89.7 0.0 3.5e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 OAP60101.1 - 0.1 11.0 0.0 0.15 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AA_permease_2 PF13520.1 OAP60102.1 - 2.6e-39 134.9 49.2 3.1e-39 134.7 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease ABC1 PF03109.11 OAP60104.1 - 6.5e-24 84.1 0.2 1.1e-20 73.7 0.0 3.1 2 1 0 2 2 2 1 ABC1 family APH PF01636.18 OAP60104.1 - 0.035 13.8 1.5 0.15 11.7 0.6 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.11 OAP60105.1 - 1.4e-33 116.0 33.1 1.9e-33 115.6 22.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 OAP60110.1 - 7.1e-15 54.5 21.7 1.1e-11 44.1 4.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_2 PF00328.17 OAP60111.1 - 2.4e-39 135.6 0.0 3.4e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Latrophilin PF02354.11 OAP60111.1 - 0.027 13.1 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region Voltage_CLC PF00654.15 OAP60112.1 - 0.013 14.5 1.7 0.013 14.5 1.2 2.1 1 1 1 2 2 2 0 Voltage gated chloride channel DUF3464 PF11947.3 OAP60112.1 - 0.29 10.5 1.4 0.73 9.2 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Tetraspannin PF00335.15 OAP60112.1 - 0.88 8.7 12.7 0.017 14.4 1.5 2.0 1 1 1 2 2 2 0 Tetraspanin family FAD_binding_3 PF01494.14 OAP60114.1 - 3.8e-12 45.9 2.5 2.6e-05 23.4 0.2 3.3 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 OAP60114.1 - 0.00016 20.7 0.0 0.00043 19.3 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP60114.1 - 0.0079 16.2 0.0 0.034 14.1 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP60114.1 - 0.011 15.5 0.1 2.1 8.0 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding MTBP_C PF14920.1 OAP60114.1 - 0.017 14.6 0.7 0.017 14.6 0.5 2.0 2 0 0 2 2 2 0 MDM2-binding Herpes_UL14 PF03580.9 OAP60114.1 - 0.087 12.6 1.4 0.21 11.3 1.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL14-like protein IQ PF00612.22 OAP60115.1 - 7.1e-05 22.1 0.7 0.0002 20.7 0.5 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Fungal_trans PF04082.13 OAP60116.1 - 4.5e-35 120.7 0.0 7.9e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60116.1 - 1.9e-05 24.4 12.3 4.8e-05 23.1 8.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S10 PF00450.17 OAP60117.1 - 4.7e-98 329.0 3.3 5.6e-98 328.8 2.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3659 PF12396.3 OAP60119.1 - 8.1e-292 941.5 155.6 5.9e-26 89.9 0.3 14.2 14 0 0 14 14 14 13 Protein of unknown function (DUF3659) FCD PF07729.7 OAP60119.1 - 0.14 12.5 5.3 2.9 8.2 4.8 2.5 2 0 0 2 2 2 0 FCD domain RPW8 PF05659.6 OAP60119.1 - 0.96 8.9 4.5 0.27 10.7 0.6 1.9 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Phage_fiber_C PF06820.7 OAP60119.1 - 1.4 9.1 10.7 1.2e+02 2.8 0.0 7.5 8 1 0 8 8 8 0 Putative prophage tail fibre C-terminus Syntaxin_2 PF14523.1 OAP60119.1 - 8.9 6.4 6.0 1.1 9.3 0.1 2.5 3 0 0 3 3 3 0 Syntaxin-like protein Acetyltransf_7 PF13508.1 OAP60120.1 - 6.3e-05 23.0 0.0 0.00013 22.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP60120.1 - 0.0059 16.5 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 OAP60120.1 - 0.0082 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP60120.1 - 0.041 13.9 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NMO PF03060.10 OAP60121.1 - 2.5e-71 240.5 5.2 3e-71 240.2 3.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAP60121.1 - 2.6e-08 33.1 2.2 4.8e-08 32.2 1.5 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAP60121.1 - 8.8e-07 28.0 2.6 1.7e-06 27.1 1.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 OAP60121.1 - 0.0041 16.0 1.4 0.0074 15.2 1.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase TIM-br_sig_trns PF09370.5 OAP60121.1 - 0.036 13.1 0.0 0.099 11.6 0.0 1.7 1 0 0 1 1 1 0 TIM-barrel signal transduction protein DHO_dh PF01180.16 OAP60121.1 - 0.065 12.1 0.2 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NmrA PF05368.8 OAP60122.1 - 2.7e-08 33.3 0.0 4.7e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP60122.1 - 0.018 15.0 1.4 0.65 9.9 0.4 2.5 2 1 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 OAP60122.1 - 0.089 12.6 0.9 0.14 12.1 0.2 1.7 2 0 0 2 2 2 0 short chain dehydrogenase AAA PF00004.24 OAP60123.1 - 1.5e-48 164.3 1.3 2.4e-41 141.0 0.0 3.6 3 1 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAP60123.1 - 7e-09 35.9 0.0 0.00039 20.4 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 OAP60123.1 - 2e-07 30.8 0.4 0.00057 19.6 0.1 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.8 OAP60123.1 - 2.4e-06 26.6 0.0 0.0036 16.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_22 PF13401.1 OAP60123.1 - 3.6e-06 27.1 0.0 0.27 11.3 0.0 3.7 3 1 0 3 3 2 2 AAA domain AAA_28 PF13521.1 OAP60123.1 - 7.3e-06 26.0 0.0 0.074 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAP60123.1 - 3e-05 24.8 0.0 0.11 13.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 OAP60123.1 - 0.00026 21.1 0.0 0.57 10.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 OAP60123.1 - 0.00029 19.9 0.0 0.0028 16.7 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 OAP60123.1 - 0.00035 20.6 0.0 0.0098 15.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 OAP60123.1 - 0.0009 18.7 0.7 1.7 8.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain Arch_ATPase PF01637.13 OAP60123.1 - 0.00092 18.9 0.0 7.2 6.2 0.0 3.2 2 1 0 3 3 3 0 Archaeal ATPase AAA_2 PF07724.9 OAP60123.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 OAP60123.1 - 0.0012 17.6 0.1 0.03 13.0 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus Rad17 PF03215.10 OAP60123.1 - 0.0015 17.3 0.0 0.01 14.5 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Bac_DnaA PF00308.13 OAP60123.1 - 0.0016 18.1 0.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein IstB_IS21 PF01695.12 OAP60123.1 - 0.0016 17.8 0.0 0.32 10.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 OAP60123.1 - 0.0027 17.6 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAP60123.1 - 0.005 16.7 0.1 6.6 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 OAP60123.1 - 0.0052 16.5 0.0 3.3 7.5 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_3 PF07726.6 OAP60123.1 - 0.0065 16.0 0.1 0.041 13.4 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 OAP60123.1 - 0.01 15.3 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain CDC48_N PF02359.13 OAP60123.1 - 0.01 15.7 0.0 0.035 14.0 0.0 1.9 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain ABC_tran PF00005.22 OAP60123.1 - 0.011 16.0 0.0 9.5 6.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 OAP60123.1 - 0.013 15.2 0.4 15 5.2 0.0 3.5 3 1 1 4 4 4 0 NACHT domain Mg_chelatase PF01078.16 OAP60123.1 - 0.031 13.4 0.1 1.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Miro PF08477.8 OAP60123.1 - 0.038 14.4 0.0 0.21 12.0 0.0 2.3 3 0 0 3 3 2 0 Miro-like protein UPF0079 PF02367.12 OAP60123.1 - 0.066 12.8 0.1 4 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2296 PF10058.4 OAP60124.1 - 2e-18 65.8 0.1 3.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Ima1_N PF09779.4 OAP60124.1 - 0.17 12.3 0.4 0.54 10.7 0.1 2.0 1 1 1 2 2 2 0 Ima1 N-terminal domain ADH_zinc_N PF00107.21 OAP60125.1 - 4.8e-15 55.2 0.0 9.5e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP60125.1 - 0.00024 20.8 0.0 0.00058 19.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyridoxal_deC PF00282.14 OAP60126.1 - 3.7e-119 397.4 0.0 4.6e-119 397.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_65m PF03632.10 OAP60127.1 - 4.8e-83 278.8 0.9 2.1e-82 276.7 0.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 OAP60127.1 - 7.2e-38 130.3 0.1 1.1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain SMC_Nse1 PF07574.8 OAP60127.1 - 8e-34 117.0 0.0 1.2e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Glyco_hydro_65C PF03633.10 OAP60127.1 - 0.00043 20.3 0.3 0.0072 16.3 0.1 2.8 3 0 0 3 3 3 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.20 OAP60127.1 - 0.0015 18.3 0.3 0.007 16.1 0.0 2.3 2 0 0 2 2 2 1 F5/8 type C domain CBFD_NFYB_HMF PF00808.18 OAP60128.1 - 8.5e-11 41.7 0.1 4.7e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Rrf2 PF02082.15 OAP60128.1 - 0.091 12.8 0.0 0.24 11.5 0.0 1.6 1 1 1 2 2 2 0 Transcriptional regulator tRNA_synt_2f PF02092.12 OAP60128.1 - 0.13 10.8 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit adh_short PF00106.20 OAP60129.1 - 5.8e-27 94.6 0.1 9.8e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP60129.1 - 8.8e-11 41.7 0.5 8.7e-09 35.2 0.1 2.1 1 1 1 2 2 2 2 KR domain adh_short_C2 PF13561.1 OAP60129.1 - 2.2e-06 27.6 0.0 2.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 OAP60129.1 - 0.0088 15.2 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 OAP60129.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 OAP60129.1 - 0.062 12.7 0.0 0.29 10.5 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP60129.1 - 0.092 11.6 0.1 0.29 9.9 0.1 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FAA_hydrolase PF01557.13 OAP60130.1 - 3.1e-61 206.5 0.0 4e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family p450 PF00067.17 OAP60131.1 - 7.1e-73 245.6 0.0 8.7e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fasciclin PF02469.17 OAP60132.1 - 4.7e-22 78.3 0.0 6e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain DUF2437 PF10370.4 OAP60132.1 - 0.1 12.9 0.0 1 9.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) VSP PF03302.8 OAP60132.1 - 0.27 9.8 1.4 0.4 9.2 1.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein adh_short PF00106.20 OAP60133.1 - 6.1e-29 101.0 5.4 9.2e-29 100.5 3.3 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60133.1 - 7.6e-21 74.9 0.0 9.3e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP60133.1 - 8.4e-14 51.6 2.8 2.7e-13 49.9 2.0 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP60133.1 - 3e-06 26.3 0.0 4.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 OAP60133.1 - 0.00054 19.4 0.5 0.00077 18.9 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP60133.1 - 0.056 12.1 0.1 0.082 11.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family E1-E2_ATPase PF00122.15 OAP60134.1 - 5.2e-60 202.3 7.1 1.1e-59 201.3 4.9 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAP60134.1 - 6.1e-23 82.3 0.0 1.3e-22 81.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAP60134.1 - 1.4e-12 48.2 0.0 3.7e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAP60134.1 - 6.9e-09 35.0 0.0 1.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAP60134.1 - 0.0012 18.4 0.3 0.0034 17.0 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP60134.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit RRM_1 PF00076.17 OAP60135.1 - 2.1e-07 30.4 0.0 3.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP60135.1 - 2.8e-05 23.8 0.0 5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 OAP60135.1 - 0.00054 20.1 0.0 0.0016 18.6 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_6 PF14259.1 OAP60135.1 - 0.0013 18.6 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.16 OAP60136.1 - 1.4e-100 336.4 0.0 1.7e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 OAP60136.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.22 OAP60137.1 - 2.1e-27 94.6 6.0 1.3e-10 40.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PALP PF00291.20 OAP60139.1 - 2e-61 207.9 0.1 2.4e-61 207.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TroA PF01297.12 OAP60139.1 - 0.024 13.8 0.1 0.19 10.9 0.5 1.8 1 1 1 2 2 2 0 Periplasmic solute binding protein family Amidohydro_4 PF13147.1 OAP60140.1 - 6.3e-24 85.4 0.1 1.7e-22 80.8 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP60140.1 - 2.1e-14 53.5 0.1 3.9e-09 36.2 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.15 OAP60140.1 - 6.6e-13 49.0 0.1 2.9e-08 33.7 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP60140.1 - 1.1e-12 47.5 0.2 3.4e-12 46.0 0.2 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 OAP60140.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Urease_alpha PF00449.15 OAP60140.1 - 0.051 13.7 0.4 0.13 12.4 0.3 1.7 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain tRNA-synt_1c PF00749.16 OAP60141.1 - 7.4e-98 327.0 0.0 1e-97 326.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 OAP60141.1 - 2e-32 112.2 0.8 5.1e-32 110.9 0.6 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_L1 PF00687.16 OAP60142.1 - 1.9e-27 96.0 0.0 2.4e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.6 OAP60143.1 - 1.6e-30 105.7 1.9 1.6e-30 105.7 1.3 1.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 OAP60143.1 - 3e-07 30.1 1.3 3e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 OAP60143.1 - 0.00014 21.8 0.8 0.00014 21.8 0.5 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 OAP60143.1 - 0.01 15.0 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 OAP60143.1 - 0.011 14.3 0.6 0.023 13.3 0.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.7 OAP60143.1 - 0.057 13.6 6.0 0.65 10.2 0.2 3.2 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.11 OAP60143.1 - 0.9 9.7 6.1 0.23 11.7 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 TSC22 PF01166.13 OAP60143.1 - 2.1 8.3 9.1 0.1 12.5 1.2 2.5 3 0 0 3 3 3 0 TSC-22/dip/bun family SGS PF05002.10 OAP60144.1 - 1.2e-23 82.6 9.8 3.6e-23 81.0 6.8 1.9 1 1 0 1 1 1 1 SGS domain CS PF04969.11 OAP60144.1 - 2.6e-16 59.9 0.0 5.4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 OAP60144.1 - 2.9e-05 23.6 0.2 6.5e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 OAP60144.1 - 0.00035 21.1 6.4 0.0051 17.4 0.9 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP60144.1 - 0.0045 17.2 0.9 2.6 8.4 0.4 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF2057 PF09829.4 OAP60144.1 - 0.0093 15.6 2.5 1.6 8.3 1.8 2.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2057) TPR_14 PF13428.1 OAP60144.1 - 0.062 13.9 6.5 0.59 10.9 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP60144.1 - 0.18 11.7 3.1 2.1 8.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PIH1 PF08190.7 OAP60144.1 - 4.4 6.6 8.2 20 4.4 0.1 2.1 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 7tm_3 PF00003.17 OAP60145.1 - 0.019 14.3 11.5 0.032 13.5 8.0 1.3 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR RdRP PF05183.7 OAP60146.1 - 1.4e-103 347.6 0.0 1.8e-103 347.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Metallophos PF00149.23 OAP60147.1 - 1.1e-41 142.5 0.9 1.6e-41 141.9 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase p450 PF00067.17 OAP60148.1 - 6e-70 236.0 0.0 9e-70 235.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Transaldolase PF00923.14 OAP60149.1 - 1.4e-65 221.2 0.1 1.7e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Creb_binding PF09030.5 OAP60150.1 - 0.0014 18.7 2.1 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 1 Creb binding Zn_clus PF00172.13 OAP60150.1 - 0.0029 17.4 0.9 0.0029 17.4 0.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1192 PF06698.6 OAP60150.1 - 0.74 9.6 4.1 1.5 8.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Aldedh PF00171.17 OAP60151.1 - 2.2e-167 557.0 0.1 2.5e-167 556.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sugar_tr PF00083.19 OAP60152.1 - 3.3e-119 398.4 19.9 3.8e-119 398.2 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60152.1 - 1.1e-28 100.0 19.9 1.1e-28 100.0 13.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclase PF04199.8 OAP60153.1 - 6.1e-14 52.0 0.2 9e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase VAD1-2 PF15310.1 OAP60154.1 - 0.056 13.1 0.1 0.081 12.5 0.1 1.3 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling 2OG-FeII_Oxy PF03171.15 OAP60157.1 - 1.3e-12 47.8 0.1 3.3e-12 46.5 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP60157.1 - 3.1e-08 34.1 0.1 5.7e-07 30.0 0.1 2.2 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DAO PF01266.19 OAP60158.1 - 2.9e-34 118.5 0.9 7.6e-34 117.1 0.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP60158.1 - 5.3e-06 26.7 0.0 0.1 13.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP60158.1 - 0.007 16.2 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP60158.1 - 0.011 15.7 0.2 0.03 14.3 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP60158.1 - 0.16 10.3 0.0 0.31 9.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein His_Phos_1 PF00300.17 OAP60159.1 - 4.8e-12 46.2 0.0 7.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3245 PF11595.3 OAP60161.1 - 0.00053 20.2 5.3 0.00053 20.2 3.7 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3245) HSF_DNA-bind PF00447.12 OAP60162.1 - 2.5e-36 123.9 2.3 3.8e-36 123.4 1.6 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Bystin PF05291.6 OAP60163.1 - 1.3e-120 401.8 0.0 1.9e-120 401.3 0.0 1.1 1 0 0 1 1 1 1 Bystin WSK PF03832.8 OAP60163.1 - 0.28 10.5 1.3 2.5 7.5 0.1 2.5 2 0 0 2 2 2 0 WSK motif HET PF06985.6 OAP60164.1 - 2.6e-32 111.8 1.5 4.1e-32 111.2 1.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidase PF01425.16 OAP60165.1 - 1.1e-106 357.3 1.7 3.8e-105 352.2 1.2 2.0 1 1 0 1 1 1 1 Amidase Fungal_trans PF04082.13 OAP60166.1 - 6.5e-09 35.0 0.1 9.6e-09 34.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TatD_DNase PF01026.16 OAP60166.1 - 2.3e-08 33.5 0.0 1e-07 31.4 0.0 1.8 1 1 0 2 2 2 1 TatD related DNase HAD_2 PF13419.1 OAP60167.1 - 2.9e-32 112.2 0.0 3.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SAP30_Sin3_bdg PF13867.1 OAP60167.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 ATP-grasp_2 PF08442.5 OAP60168.1 - 8.3e-81 270.1 0.3 1.3e-80 269.5 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 OAP60168.1 - 3.4e-23 81.9 0.3 6.2e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 OAP60168.1 - 2.1e-08 33.6 0.7 4.6e-08 32.5 0.1 1.8 2 0 0 2 2 2 1 ATP-grasp domain Peripla_BP_2 PF01497.13 OAP60168.1 - 0.0019 17.3 0.7 0.0034 16.5 0.2 1.6 2 0 0 2 2 2 1 Periplasmic binding protein GARS_A PF01071.14 OAP60168.1 - 0.0084 15.6 0.3 0.029 13.9 0.0 2.0 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 OAP60168.1 - 0.043 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain zf-His_Me_endon PF05551.6 OAP60169.1 - 9.4e-12 45.0 2.1 9.4e-12 45.0 1.5 1.8 2 0 0 2 2 2 1 Zinc-binding loop region of homing endonuclease Myb_DNA-bind_2 PF08914.6 OAP60170.1 - 2.7e-09 36.6 0.0 7.1e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 OAP60170.1 - 0.069 13.7 0.0 0.17 12.4 0.0 1.7 1 1 0 1 1 1 0 Rap1, DNA-binding DUF4191 PF13829.1 OAP60170.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Kinesin PF00225.18 OAP60171.1 - 4.4e-14 51.9 0.0 2.9e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain IncA PF04156.9 OAP60171.1 - 0.0058 16.2 3.5 0.012 15.1 2.4 1.5 1 0 0 1 1 1 1 IncA protein HALZ PF02183.13 OAP60171.1 - 0.014 15.0 2.8 0.54 10.0 0.5 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 OAP60171.1 - 0.027 13.9 0.3 0.027 13.9 0.2 2.7 3 0 0 3 3 3 0 Septum formation initiator bZIP_1 PF00170.16 OAP60171.1 - 0.03 14.2 2.3 0.13 12.2 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 OAP60171.1 - 0.17 12.2 2.3 4.5 7.6 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 OAP60171.1 - 0.29 10.9 9.4 0.1 12.4 3.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 OAP60171.1 - 0.73 9.4 2.6 1.2 8.8 0.9 1.9 1 1 1 2 2 2 0 Mnd1 family DUF4140 PF13600.1 OAP60171.1 - 1.7 9.1 9.4 3.1 8.2 0.0 4.2 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 OAP60171.1 - 3.7 7.4 5.8 11 5.9 0.3 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.1 OAP60171.1 - 4.3 7.3 15.0 1.4 8.9 0.4 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 SNF2_N PF00176.18 OAP60172.1 - 1.3e-17 63.5 0.0 1.8e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP60172.1 - 8e-09 35.2 0.0 1.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PepSY_TM_3 PF13706.1 OAP60173.1 - 3.1 7.2 6.6 7.1 6.1 4.6 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix DUF4193 PF13834.1 OAP60176.1 - 0.0063 16.6 1.2 0.55 10.4 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4193) GATA PF00320.22 OAP60176.1 - 0.082 12.2 6.0 1.9 7.9 0.1 2.7 2 0 0 2 2 2 0 GATA zinc finger zf-UDP PF14569.1 OAP60176.1 - 0.4 10.4 5.5 3.5 7.4 0.9 2.8 1 1 0 2 2 2 0 Zinc-binding RING-finger FYVE PF01363.16 OAP60176.1 - 0.55 10.1 8.6 19 5.2 6.0 2.4 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_2 PF13923.1 OAP60176.1 - 1.9 8.5 6.1 0.23 11.5 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP60176.1 - 2 8.1 5.4 0.82 9.3 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.18 OAP60180.1 - 1.4e-08 33.9 0.0 4.7e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP60180.1 - 0.00013 21.7 0.1 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Gon7 PF08738.5 OAP60180.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Gon7 family DUF4527 PF15030.1 OAP60182.1 - 0.12 11.6 0.1 0.25 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) DUF3225 PF11533.3 OAP60183.1 - 0.06 13.0 0.0 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) AAA_27 PF13514.1 OAP60185.1 - 0.033 11.8 0.3 0.04 11.6 0.2 1.1 1 0 0 1 1 1 0 AAA domain Penicil_amidase PF01804.13 OAP60186.1 - 0.07 12.1 0.5 0.077 12.0 0.4 1.0 1 0 0 1 1 1 0 Penicillin amidase SLAC1 PF03595.12 OAP60189.1 - 3.6e-76 255.9 54.6 4.1e-76 255.7 37.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pro_CA PF00484.14 OAP60190.1 - 1e-27 97.0 0.0 1.3e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase GCIP PF13324.1 OAP60191.1 - 5.3e-11 42.2 0.5 7.6e-11 41.7 0.3 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 OAP60191.1 - 0.0045 16.6 0.6 0.0069 16.0 0.4 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region PMC2NT PF08066.7 OAP60191.1 - 0.055 13.7 0.2 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Lactamase_B PF00753.22 OAP60192.1 - 6e-09 35.8 2.2 1.4e-08 34.6 1.5 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP60192.1 - 4.1e-05 23.1 0.0 5.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lipoprotein_3 PF00938.12 OAP60192.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein MFS_1 PF07690.11 OAP60193.1 - 1.4e-36 125.9 22.8 2e-36 125.4 15.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 OAP60194.1 - 3.9e-60 203.6 0.0 4.6e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.1 OAP60195.1 - 1.3e-13 50.9 0.0 2.6e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP60195.1 - 3e-10 39.9 0.0 7.7e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP60195.1 - 1.2e-07 31.6 0.0 2.5e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAP60195.1 - 8.3e-06 25.6 0.7 0.0016 18.3 0.0 2.6 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 OAP60195.1 - 0.00019 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.1 OAP60195.1 - 0.00043 20.7 0.0 0.0036 17.7 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAP60195.1 - 0.003 17.7 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NMT1 PF09084.6 OAP60196.1 - 2.9e-05 23.7 0.0 0.0029 17.2 0.0 2.4 2 0 0 2 2 2 2 NMT1/THI5 like Phosphonate-bd PF12974.2 OAP60196.1 - 0.014 14.7 0.0 0.099 12.0 0.0 2.1 2 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein GMC_oxred_N PF00732.14 OAP60197.1 - 1.8e-45 155.3 0.0 2.7e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP60197.1 - 5.3e-32 111.0 0.0 8.1e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP60197.1 - 6.5e-07 28.5 0.1 0.0011 17.9 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP60197.1 - 0.0014 17.5 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP60197.1 - 0.0018 18.2 0.7 0.0056 16.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 OAP60197.1 - 0.14 10.7 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Fungal_trans PF04082.13 OAP60198.1 - 1.8e-33 115.5 0.2 2.7e-33 114.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60198.1 - 5.2e-10 39.0 6.5 8.7e-10 38.3 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.9 OAP60199.1 - 3.1e-42 145.0 0.2 3.7e-42 144.7 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Cupin_2 PF07883.6 OAP60200.1 - 2e-20 72.0 1.3 2.4e-18 65.4 0.2 2.5 2 1 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 OAP60200.1 - 2.7e-05 23.8 0.2 5.4e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 OAP60200.1 - 3.4e-05 23.1 0.1 0.02 14.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Auxin_BP PF02041.11 OAP60200.1 - 4e-05 23.1 0.0 0.027 13.9 0.0 2.4 2 0 0 2 2 2 2 Auxin binding protein Cupin_1 PF00190.17 OAP60200.1 - 0.00016 21.1 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 Cupin DUF3932 PF13068.1 OAP60200.1 - 0.048 13.7 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) FAD_binding_3 PF01494.14 OAP60201.1 - 2.2e-26 92.7 0.0 2.7e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP60201.1 - 6.5e-10 38.4 6.5 2.5e-05 23.3 1.3 3.1 1 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP60201.1 - 5.5e-08 32.7 0.3 1.5e-07 31.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP60201.1 - 7.9e-08 32.4 0.0 1.9e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP60201.1 - 2.6e-07 29.6 2.5 0.002 16.8 0.0 2.9 1 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 OAP60201.1 - 2.9e-07 30.7 1.4 0.001 19.4 0.6 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP60201.1 - 8.1e-07 27.8 0.6 0.00067 18.2 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 OAP60201.1 - 1.2e-06 27.9 0.0 1.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP60201.1 - 1.5e-06 27.3 0.2 8.8e-06 24.8 0.1 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.19 OAP60201.1 - 1.2e-05 24.5 0.1 0.078 12.0 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 OAP60201.1 - 5.7e-05 22.1 4.1 8.3e-05 21.6 2.3 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 OAP60201.1 - 0.00037 20.2 0.9 0.0013 18.4 0.2 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 OAP60201.1 - 0.00058 18.8 0.7 0.00094 18.1 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 OAP60201.1 - 0.0008 18.5 0.6 0.0016 17.5 0.4 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 OAP60201.1 - 0.0017 17.9 0.2 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 OAP60201.1 - 0.076 13.0 0.1 0.25 11.3 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 OAP60201.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.13 OAP60201.1 - 0.18 11.4 1.0 0.32 10.6 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 OAP60202.1 - 3.5e-92 309.3 26.1 4.1e-92 309.1 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60202.1 - 6.3e-25 87.6 23.5 6.3e-25 87.6 16.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.1 OAP60203.1 - 6e-23 81.8 0.0 8e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP60203.1 - 3.3e-21 75.9 2.0 1.2e-20 74.0 0.4 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP60203.1 - 5.4e-11 42.4 0.1 4.2e-10 39.5 0.1 2.4 1 1 0 1 1 1 1 KR domain Aldedh PF00171.17 OAP60204.1 - 8e-164 545.3 0.2 9.4e-164 545.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cyclase PF04199.8 OAP60205.1 - 5.5e-13 48.9 0.1 7.9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Glyoxalase_2 PF12681.2 OAP60206.1 - 5.2e-14 52.7 0.0 6.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP60206.1 - 3.4e-11 43.2 0.0 4.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 OAP60206.1 - 2e-09 37.4 0.0 7.1e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 OAP60206.1 - 3.7e-05 23.6 0.0 0.00018 21.4 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Aldo_ket_red PF00248.16 OAP60207.1 - 2.7e-52 177.3 0.0 3.1e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 OAP60208.1 - 5.5e-18 64.7 0.3 8.6e-18 64.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60208.1 - 7.2e-05 22.6 14.3 0.00015 21.6 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 OAP60209.1 - 2.7e-28 97.9 0.4 5.6e-28 96.8 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP60209.1 - 5.4e-24 84.2 0.0 8.3e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP60209.1 - 0.00066 20.5 0.0 0.0013 19.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAP60209.1 - 0.0029 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAP60209.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 OAP60209.1 - 0.071 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_N PF08240.7 OAP60210.1 - 1.1e-28 99.1 1.8 1.3e-28 98.9 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP60210.1 - 5.7e-16 58.2 0.9 1.1e-15 57.3 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP60210.1 - 3.2e-07 31.2 0.1 1e-06 29.6 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 OAP60210.1 - 0.052 12.0 1.6 0.075 11.4 1.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 OAP60211.1 - 6.8e-26 91.5 0.0 2.1e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP60211.1 - 7.5e-13 47.5 0.0 1.9e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP60211.1 - 4.7e-10 38.9 0.1 1.3e-07 30.9 0.1 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP60211.1 - 2.9e-09 36.8 0.0 7.9e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP60211.1 - 6.3e-09 36.0 0.0 2e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP60211.1 - 0.0014 17.6 0.1 0.98 8.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP60211.1 - 0.0079 15.9 0.1 0.17 11.6 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAP60211.1 - 0.043 12.7 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Transketolase_N PF00456.16 OAP60212.1 - 7.8e-101 337.2 0.1 1.1e-100 336.7 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 OAP60212.1 - 1.6e-35 122.1 0.3 3.7e-35 120.9 0.2 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAP60212.1 - 2.1e-11 43.8 0.0 5.3e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 OAP60212.1 - 2.7e-07 29.7 0.0 0.0021 17.0 0.0 2.3 2 0 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 OAP60212.1 - 0.039 12.6 0.0 0.076 11.7 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component adh_short_C2 PF13561.1 OAP60213.1 - 6.3e-27 94.8 0.2 8.8e-27 94.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP60213.1 - 6.7e-26 91.1 5.9 2e-25 89.6 4.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP60213.1 - 3.6e-09 36.5 4.0 6.9e-09 35.6 2.4 1.7 2 1 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP60213.1 - 0.013 15.2 0.2 0.035 13.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP60214.1 - 1.8e-11 43.9 0.2 1.8e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 OAP60214.1 - 9.5e-08 32.3 0.2 6.1e-07 29.7 0.0 2.3 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 OAP60214.1 - 0.00024 19.9 0.0 0.026 13.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 OAP60214.1 - 0.0036 16.6 0.1 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP60214.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 OAP60214.1 - 0.0078 15.2 0.0 0.011 14.6 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 OAP60214.1 - 0.032 13.1 0.2 0.33 9.8 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DXP_reductoisom PF02670.11 OAP60214.1 - 0.05 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.7 OAP60214.1 - 0.052 12.4 0.0 0.18 10.7 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein Abhydrolase_6 PF12697.2 OAP60215.1 - 6e-30 104.8 2.1 8.9e-30 104.2 1.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP60215.1 - 4e-20 72.3 0.7 1.2e-19 70.7 0.5 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP60215.1 - 2.8e-12 46.5 0.0 2.8e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP60215.1 - 3.6e-05 23.5 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase FAD_binding_4 PF01565.18 OAP60216.1 - 2.1e-21 75.8 2.9 4.8e-21 74.6 2.0 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAP60216.1 - 2.5e-13 49.6 0.0 6.3e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 OAP60216.1 - 0.013 14.6 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Bul1_N PF04425.7 OAP60217.1 - 0.02 13.4 0.0 0.056 12.0 0.0 1.6 2 0 0 2 2 2 0 Bul1 N terminus Bul1_C PF04426.7 OAP60217.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus AIG1 PF04548.11 OAP60218.1 - 1.2e-09 37.5 0.0 2.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 OAP60218.1 - 2.3e-09 37.2 0.0 1.1e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 OAP60218.1 - 3.8e-05 23.2 0.1 0.00031 20.2 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 OAP60218.1 - 4.3e-05 23.3 1.6 0.049 13.4 0.1 2.9 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 OAP60218.1 - 0.00021 20.5 0.0 0.00068 18.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 OAP60218.1 - 0.00085 18.2 0.0 0.0018 17.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.13 OAP60218.1 - 0.0011 18.0 0.1 0.0078 15.2 0.0 2.1 1 1 0 1 1 1 1 Septin T2SE PF00437.15 OAP60218.1 - 0.0069 15.3 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein UPF0079 PF02367.12 OAP60218.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 OAP60218.1 - 0.023 13.3 0.0 0.049 12.2 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 OAP60218.1 - 0.03 14.2 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 OAP60218.1 - 0.031 14.5 0.1 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.5 OAP60218.1 - 0.039 13.1 0.2 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.12 OAP60218.1 - 0.044 13.2 0.1 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 OAP60218.1 - 0.044 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 OAP60218.1 - 0.046 13.6 0.6 0.17 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 OAP60218.1 - 0.053 13.3 1.3 0.1 12.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF87 PRP1_N PF06424.7 OAP60218.1 - 0.084 13.2 2.6 0.14 12.4 1.8 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal AAA_29 PF13555.1 OAP60218.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 OAP60218.1 - 0.15 12.2 0.8 0.66 10.1 0.0 2.5 3 1 1 4 4 3 0 AAA domain MobB PF03205.9 OAP60218.1 - 0.15 11.7 0.5 0.75 9.5 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 OAP60218.1 - 0.2 11.0 0.0 0.2 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA-like domain Macoilin PF09726.4 OAP60219.1 - 0.048 11.9 0.1 0.074 11.3 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein HSP70 PF00012.15 OAP60220.1 - 7.7e-08 30.7 0.1 7.2e-07 27.5 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Amidase PF01425.16 OAP60221.1 - 3.2e-80 270.1 0.0 3.9e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Amino_oxidase PF01593.19 OAP60222.1 - 8.5e-51 173.4 0.1 3.4e-50 171.4 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 OAP60222.1 - 5.7e-19 68.0 0.0 1.3e-18 66.9 0.0 1.6 2 0 0 2 2 2 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 OAP60222.1 - 4.4e-13 49.0 0.1 1e-12 47.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP60222.1 - 7.2e-10 38.2 1.5 1.8e-08 33.6 1.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP60222.1 - 2.3e-07 29.9 1.7 4e-07 29.2 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAP60222.1 - 6.7e-07 28.6 0.1 1.1e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 OAP60222.1 - 7.7e-07 29.3 0.1 4e-06 27.0 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP60222.1 - 4.9e-05 22.5 1.0 7.1e-05 22.0 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 OAP60222.1 - 6.7e-05 23.2 0.1 0.00016 22.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP60222.1 - 0.00047 19.1 0.1 0.006 15.5 0.3 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAP60222.1 - 0.00048 20.0 0.2 0.00075 19.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP60222.1 - 0.00074 18.1 0.1 0.0022 16.5 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 OAP60222.1 - 0.00096 18.1 0.2 0.0013 17.6 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 OAP60222.1 - 0.0011 18.1 2.2 0.0017 17.4 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF2231 PF09990.4 OAP60223.1 - 3.4e-08 33.7 0.1 6.5e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) 2OG-FeII_Oxy PF03171.15 OAP60224.1 - 7.3e-07 29.4 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP60224.1 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DJ-1_PfpI PF01965.19 OAP60225.1 - 1.6e-10 40.5 0.0 7.1e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 OAP60225.1 - 0.0015 17.8 0.0 0.0092 15.2 0.0 1.9 1 1 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 OAP60225.1 - 0.05 13.2 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GMC_oxred_N PF00732.14 OAP60226.1 - 8.2e-09 35.0 0.0 4.1e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP60226.1 - 1.8e-08 34.8 0.3 7.1e-08 32.8 0.2 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAP60226.1 - 4.3e-05 22.5 0.2 7.1e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_5 PF12695.2 OAP60226.1 - 0.00025 20.8 0.0 0.011 15.5 0.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family DAO PF01266.19 OAP60226.1 - 0.0025 16.7 0.7 0.037 12.9 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP60226.1 - 0.0055 16.7 0.5 0.016 15.1 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 OAP60226.1 - 0.015 14.4 0.5 0.023 13.7 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP60226.1 - 0.021 14.7 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP60226.1 - 0.069 11.6 0.1 0.12 10.8 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 OAP60226.1 - 0.075 12.0 0.2 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 OAP60226.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF95 PF01944.12 OAP60227.1 - 0.051 13.2 4.9 0.095 12.3 3.4 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF95 DUF3089 PF11288.3 OAP60227.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lipase_GDSL_2 PF13472.1 OAP60228.1 - 8.1e-18 65.1 1.4 1.1e-17 64.7 1.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 OAP60228.1 - 9.4e-09 35.4 1.7 2.7e-08 33.9 1.2 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.19 OAP60229.1 - 1.2e-93 314.1 17.8 1.4e-93 313.9 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60229.1 - 3.7e-14 52.2 33.6 1e-09 37.5 9.4 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 OAP60229.1 - 0.00081 19.3 3.8 0.16 11.9 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) DUF4216 PF13952.1 OAP60229.1 - 0.07 12.6 0.1 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4216) Cytochrom_B561 PF03188.11 OAP60230.1 - 9.1e-07 28.7 9.5 9.1e-07 28.7 6.6 2.0 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DOMON PF03351.12 OAP60230.1 - 0.00027 20.8 0.0 0.00066 19.5 0.0 1.7 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 OAP60230.1 - 0.0011 18.4 3.8 0.0011 18.4 2.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) SdpI PF13630.1 OAP60230.1 - 0.0031 17.1 2.8 0.2 11.3 0.3 2.5 2 0 0 2 2 2 2 SdpI/YhfL protein family Ribosomal_S11 PF00411.14 OAP60232.1 - 3.5e-41 139.8 0.4 4.3e-41 139.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 OAP60232.1 - 0.042 12.7 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) AAR2 PF05282.6 OAP60233.1 - 1.2e-65 221.8 0.0 1.8e-65 221.2 0.0 1.2 1 1 0 1 1 1 1 AAR2 protein Gp49 PF05973.9 OAP60233.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) Ribosomal_S9 PF00380.14 OAP60234.1 - 1.7e-40 138.0 0.3 1.9e-40 137.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 OAP60234.1 - 0.083 10.3 0.0 0.092 10.2 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Ribosomal_L13 PF00572.13 OAP60235.1 - 2.6e-42 143.9 0.0 3.3e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 OAP60236.1 - 4.5e-84 279.4 3.1 3.7e-46 156.6 1.0 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.1 OAP60237.1 - 2.7e-130 434.2 1.6 4.3e-130 433.6 1.1 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 OAP60237.1 - 3.3e-83 278.1 0.0 2.7e-82 275.1 0.0 2.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 OAP60237.1 - 6.8e-39 132.3 0.1 2.9e-38 130.3 0.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 OAP60237.1 - 3.6e-25 87.6 1.9 5.2e-24 83.9 0.1 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 OAP60237.1 - 4.1e-13 48.8 7.7 9e-13 47.7 5.4 1.6 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.4 OAP60237.1 - 4.8e-06 25.1 0.0 1.2 7.2 0.0 4.5 4 1 1 5 5 5 2 Proteasome non-ATPase 26S subunit Uds1 PF15456.1 OAP60237.1 - 0.0022 17.9 6.8 0.0059 16.6 4.7 1.7 1 0 0 1 1 1 1 Up-regulated During Septation Arm PF00514.18 OAP60237.1 - 0.0087 15.8 0.1 0.1 12.4 0.1 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat OmpH PF03938.9 OAP60237.1 - 0.086 12.7 5.4 0.17 11.8 3.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_GPO PF05929.6 OAP60237.1 - 3.2 6.9 6.6 2.1 7.5 1.3 2.5 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase LON PF02190.11 OAP60238.1 - 1.6e-25 89.9 0.0 2.4e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-RING_5 PF14634.1 OAP60238.1 - 4.8e-11 42.2 20.8 4.2e-08 32.7 6.9 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.1 OAP60238.1 - 8.8e-11 41.4 20.2 2.3e-08 33.7 7.7 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 OAP60238.1 - 1.2e-09 37.6 17.8 2.7e-06 26.9 6.8 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAP60238.1 - 1.3e-09 37.7 20.5 6.9e-06 25.8 6.3 2.7 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 OAP60238.1 - 4e-09 36.3 21.5 6.7e-07 29.2 6.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP60238.1 - 9.6e-08 31.5 17.4 7.2e-07 28.7 5.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 OAP60238.1 - 0.0022 17.5 7.6 0.0022 17.5 5.3 2.8 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 OAP60238.1 - 0.0023 17.6 11.0 0.058 13.1 3.0 2.5 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 OAP60238.1 - 0.0029 17.6 3.3 0.01 15.9 2.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 OAP60238.1 - 0.0033 17.0 14.9 0.042 13.5 3.5 2.8 3 0 0 3 3 3 2 RING-type zinc-finger zf-P11 PF03854.9 OAP60238.1 - 0.11 12.0 5.1 0.4 10.1 3.6 1.9 1 0 0 1 1 1 0 P-11 zinc finger Baculo_IE-1 PF05290.6 OAP60238.1 - 0.8 9.4 4.4 1.7 8.3 0.3 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Amidase PF01425.16 OAP60239.1 - 8e-57 193.0 0.0 2.7e-55 187.9 0.0 2.3 1 1 0 1 1 1 1 Amidase Glyco_hydro_43 PF04616.9 OAP60240.1 - 2.9e-74 249.7 0.5 3.7e-74 249.4 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 OAP60241.1 - 5.1e-77 259.3 21.1 6.3e-77 259.0 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60241.1 - 5.1e-26 91.2 19.9 1.8e-21 76.2 4.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP60241.1 - 1.4e-05 23.5 2.3 1.4e-05 23.5 1.6 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Thioredoxin PF00085.15 OAP60242.1 - 6e-06 25.8 0.0 1.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAP60242.1 - 0.001 19.2 0.0 0.0036 17.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAP60242.1 - 0.15 12.1 0.0 0.91 9.6 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like PWI PF01480.12 OAP60244.1 - 3.3e-12 46.3 0.1 8.5e-12 45.0 0.1 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 OAP60244.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP60244.1 - 0.022 14.7 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 OAP60245.1 - 0.0002 21.2 11.7 0.00066 19.5 8.1 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NCA2 PF08637.5 OAP60246.1 - 8e-89 297.3 0.1 1.3e-88 296.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.17 OAP60247.1 - 3.9e-65 218.1 0.0 4.7e-65 217.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP60247.1 - 3.5e-19 69.4 0.0 4.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP60247.1 - 4.2e-13 48.9 0.0 5.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAP60247.1 - 5.4e-06 25.7 0.0 6.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAP60247.1 - 9.2e-06 25.2 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAP60247.1 - 0.0055 16.6 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAP60247.1 - 0.019 14.1 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 OAP60247.1 - 0.046 12.9 0.0 0.18 11.0 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 OAP60247.1 - 0.085 12.0 0.1 0.35 10.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAP60247.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Profilin PF00235.14 OAP60248.1 - 2.4e-44 150.3 0.3 2.7e-44 150.1 0.2 1.0 1 0 0 1 1 1 1 Profilin Tox-ODYAM1 PF15642.1 OAP60248.1 - 0.074 11.7 0.1 0.092 11.3 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus adh_short PF00106.20 OAP60249.1 - 4.5e-30 104.7 0.4 5.9e-30 104.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60249.1 - 1.5e-27 96.9 0.5 1.8e-27 96.7 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP60249.1 - 2.9e-09 36.8 0.2 4.4e-09 36.2 0.2 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 OAP60249.1 - 0.0013 19.0 1.8 0.0054 17.1 1.1 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAP60249.1 - 0.0013 18.3 0.4 0.002 17.7 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 OAP60249.1 - 0.0093 15.4 0.3 0.019 14.4 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP60249.1 - 0.027 13.3 1.1 0.037 12.9 0.8 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AdoHcyase_NAD PF00670.16 OAP60249.1 - 0.11 12.3 0.7 0.21 11.3 0.4 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 OAP60249.1 - 0.14 12.4 0.5 0.27 11.5 0.3 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding HET PF06985.6 OAP60250.1 - 1.7e-23 83.3 0.6 1.7e-23 83.3 0.4 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Utp21 PF04192.7 OAP60252.1 - 4.7e-61 205.9 0.4 7e-61 205.3 0.3 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 OAP60252.1 - 5.5e-17 60.9 16.9 0.0057 16.4 0.0 9.3 9 0 0 9 9 9 5 WD domain, G-beta repeat Utp12 PF04003.7 OAP60252.1 - 4.6e-05 23.2 0.0 9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family PQQ PF01011.16 OAP60252.1 - 0.0046 16.4 0.1 3.6 7.2 0.0 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat Cytochrom_D1 PF02239.11 OAP60252.1 - 0.0068 14.7 0.0 0.047 11.9 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain UTP15_C PF09384.5 OAP60252.1 - 0.19 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 UTP15 C terminal His_Phos_2 PF00328.17 OAP60253.1 - 8.9e-116 387.0 0.3 1.3e-115 386.4 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 OAP60253.1 - 3e-08 33.3 0.0 6.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain RNase_T PF00929.19 OAP60254.1 - 1.6e-10 41.5 0.0 1.1e-08 35.4 0.0 2.2 2 0 0 2 2 2 2 Exonuclease BTK PF00779.14 OAP60254.1 - 1 9.0 6.4 0.12 12.0 1.3 1.8 2 0 0 2 2 2 0 BTK motif PGI PF00342.14 OAP60255.1 - 2.1e-214 712.4 0.3 2.4e-214 712.2 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Arc_PepC PF06819.6 OAP60255.1 - 0.16 11.9 0.8 0.89 9.5 0.2 2.3 1 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain GMC_oxred_N PF00732.14 OAP60258.1 - 6.6e-67 225.7 0.0 2.6e-66 223.7 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP60258.1 - 5.6e-35 120.7 0.2 1e-34 119.8 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAP60258.1 - 1.5e-06 27.3 0.6 0.024 13.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP60258.1 - 0.0003 19.8 2.8 0.023 13.6 0.4 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP60258.1 - 0.0013 17.7 0.0 0.0038 16.1 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP60258.1 - 0.0024 17.8 0.0 0.0068 16.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP60258.1 - 0.031 14.3 0.1 2.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP60258.1 - 0.1 12.4 0.3 4.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAGK_cat PF00781.19 OAP60259.1 - 7.5e-10 38.3 0.0 1.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PAS_3 PF08447.6 OAP60259.1 - 0.043 13.9 0.4 3 8.0 0.0 2.4 2 0 0 2 2 2 0 PAS fold Metallophos PF00149.23 OAP60261.1 - 4e-07 29.6 2.6 1.6e-06 27.6 1.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP60261.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peripla_BP_3 PF13377.1 OAP60261.1 - 0.16 12.0 0.1 1.9 8.4 0.0 2.3 2 1 0 2 2 2 0 Periplasmic binding protein-like domain Pkinase PF00069.20 OAP60262.1 - 5.2e-41 140.5 0.0 1.6e-24 86.4 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP60262.1 - 1e-13 50.9 0.1 2.3e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase P3A PF08727.6 OAP60263.1 - 0.024 13.9 0.2 0.05 12.9 0.1 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like Phytochelatin_C PF09328.5 OAP60263.1 - 0.1 12.0 1.8 0.13 11.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Mei4 PF13971.1 OAP60263.1 - 0.12 11.3 2.7 0.057 12.3 0.4 1.4 2 0 0 2 2 2 0 Meiosis-specific protein Mei4 FRG2 PF15315.1 OAP60263.1 - 0.19 11.6 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Pup PF05639.6 OAP60263.1 - 2.6 8.5 6.1 6.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Pup-like protein Gemini_mov PF01708.11 OAP60264.1 - 0.097 12.2 0.0 0.33 10.5 0.0 1.9 1 0 0 1 1 1 0 Geminivirus putative movement protein FTR1 PF03239.9 OAP60264.1 - 0.15 11.0 0.4 0.2 10.5 0.2 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family SLAC1 PF03595.12 OAP60265.1 - 9.1e-62 208.6 57.5 1e-61 208.4 39.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TMEM141 PF15110.1 OAP60265.1 - 0.061 13.6 0.8 0.29 11.4 0.1 2.4 2 0 0 2 2 2 0 TMEM141 protein family eIF-3c_N PF05470.7 OAP60266.1 - 5e-174 579.7 27.9 4.3e-136 454.4 1.3 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 OAP60266.1 - 9.5e-15 54.8 1.1 6.6e-13 48.8 0.0 3.2 2 0 0 2 2 2 1 PCI domain Pkinase PF00069.20 OAP60267.1 - 2.5e-52 177.6 0.0 6.5e-52 176.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP60267.1 - 9.2e-24 83.8 0.1 3.7e-23 81.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 OAP60267.1 - 8.4e-05 22.4 7.6 0.00055 19.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 OAP60267.1 - 0.003 16.9 0.2 0.014 14.7 0.1 2.0 1 1 0 1 1 1 1 RIO1 family SNF2_N PF00176.18 OAP60268.1 - 1.5e-69 234.1 0.0 2.4e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP60268.1 - 2e-14 53.1 0.0 5.4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EAP30 PF04157.11 OAP60269.1 - 8.1e-55 185.4 0.0 9.1e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family TSKS PF15358.1 OAP60269.1 - 0.018 13.2 0.1 0.025 12.7 0.1 1.2 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Chlorophyllase PF07224.6 OAP60269.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ribosomal_L30_N PF08079.7 OAP60270.1 - 3.3e-24 84.6 14.6 6.5e-24 83.7 10.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 OAP60270.1 - 1.2e-17 63.1 3.6 1.6e-17 62.7 1.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e GFA PF04828.9 OAP60271.1 - 2.2e-08 33.9 0.1 2.2e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Tnp_zf-ribbon_2 PF13842.1 OAP60271.1 - 0.37 11.2 4.1 0.61 10.5 0.1 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DNA_pol_B PF00136.16 OAP60273.1 - 1.6e-113 379.9 3.7 1.6e-113 379.9 2.6 2.2 3 0 0 3 3 3 1 DNA polymerase family B zf-DNA_Pol PF08996.5 OAP60273.1 - 3.9e-65 218.7 4.1 9.9e-65 217.4 2.8 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 OAP60273.1 - 1.7e-37 129.0 0.0 3e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 OAP60273.1 - 6.1e-25 86.8 8.5 6.1e-25 86.8 5.9 3.2 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal MGDG_synth PF06925.6 OAP60273.1 - 0.15 11.9 0.1 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase Phos_pyr_kin PF08543.7 OAP60274.1 - 1.6e-78 263.3 3.6 2.3e-78 262.7 2.5 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 OAP60274.1 - 8.9e-50 169.3 0.4 1.3e-49 168.7 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 OAP60274.1 - 2.4e-06 26.9 0.2 4.1e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 OAP60274.1 - 0.0034 16.5 2.0 0.015 14.4 0.2 2.2 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Methyltransf_28 PF02636.12 OAP60275.1 - 1.3e-71 240.9 0.0 1.6e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PPR_2 PF13041.1 OAP60277.1 - 6.1e-24 83.7 0.0 8.7e-18 64.0 0.0 3.3 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 OAP60277.1 - 4.2e-06 26.3 0.4 0.0029 17.4 0.0 4.3 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.2 OAP60277.1 - 6.6e-06 25.5 0.0 0.9 9.0 0.0 4.0 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 OAP60277.1 - 6.3e-05 22.9 0.8 0.68 10.3 0.0 5.1 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Polysacc_deac_1 PF01522.16 OAP60277.1 - 0.098 12.2 0.2 0.65 9.6 0.1 2.4 2 1 1 3 3 3 0 Polysaccharide deacetylase DUF4557 PF15101.1 OAP60277.1 - 1.3 8.8 5.7 2.8 7.7 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF972 PF06156.8 OAP60278.1 - 8.5 6.7 6.7 3.3 8.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DEAD PF00270.24 OAP60280.1 - 1.1e-45 155.1 0.0 4.4e-44 149.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP60280.1 - 4.4e-28 96.9 0.0 1.1e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP60280.1 - 7.7e-05 22.6 0.0 0.00025 20.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 OAP60280.1 - 0.00041 20.3 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 OAP60280.1 - 0.0074 14.7 0.0 0.41 8.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) DUF2443 PF10398.4 OAP60280.1 - 0.068 12.9 0.3 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Fungal_trans PF04082.13 OAP60281.1 - 3e-13 49.2 1.7 5.1e-13 48.5 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ctr PF04145.10 OAP60281.1 - 0.12 12.3 0.1 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Ctr copper transporter family Chitin_synth_1 PF01644.12 OAP60283.1 - 8.3e-85 282.5 0.2 1.2e-84 282.0 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAP60283.1 - 1.7e-33 114.1 0.1 4.1e-33 112.9 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAP60283.1 - 1.3e-20 73.3 0.7 2.3e-19 69.2 0.0 2.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 OAP60283.1 - 6.7e-08 32.4 0.2 6.7e-08 32.4 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAP60283.1 - 4.1e-05 23.5 0.0 7.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Hist_deacetyl PF00850.14 OAP60285.1 - 5.6e-57 193.3 0.4 8.3e-57 192.8 0.3 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ApbA_C PF08546.6 OAP60286.1 - 1.6e-27 96.0 0.0 3.6e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 OAP60286.1 - 1.3e-24 86.3 0.0 1.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TGT PF01702.13 OAP60287.1 - 4.7e-41 140.6 0.0 6.6e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DND1_DSRM PF14709.1 OAP60288.1 - 0.059 13.6 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 WxL PF13731.1 OAP60288.1 - 0.092 12.5 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 WxL domain surface cell wall-binding dsrm PF00035.20 OAP60288.1 - 0.098 13.2 0.1 0.22 12.1 0.0 1.6 1 1 0 1 1 1 0 Double-stranded RNA binding motif R3H-assoc PF13902.1 OAP60290.1 - 8.6e-11 41.9 0.4 2.8e-10 40.2 0.2 1.9 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.17 OAP60290.1 - 0.027 14.1 0.0 0.097 12.3 0.0 2.0 1 0 0 1 1 1 0 R3H domain Peptidase_M28 PF04389.12 OAP60291.1 - 3.2e-26 92.1 0.1 6.1e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 OAP60291.1 - 8.4e-07 28.6 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1774 PF08611.5 OAP60292.1 - 1.5e-34 118.0 1.9 5e-34 116.3 1.3 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1774) Mtp PF03821.11 OAP60292.1 - 0.26 10.6 2.3 0.19 11.1 0.1 1.8 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter zf-RING_2 PF13639.1 OAP60293.1 - 0.016 15.0 3.0 0.032 14.0 2.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 OAP60293.1 - 0.027 14.3 2.0 0.053 13.3 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Virulence_RhuM PF13310.1 OAP60293.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Virulence protein RhuM family zf-rbx1 PF12678.2 OAP60293.1 - 0.22 11.6 2.9 0.49 10.5 2.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger ADH_N PF08240.7 OAP60297.1 - 5.2e-26 90.5 0.1 9.5e-26 89.7 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP60297.1 - 3.6e-20 71.8 0.4 7.9e-20 70.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP60297.1 - 0.0023 18.8 0.1 0.017 16.0 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.15 OAP60297.1 - 0.042 13.7 0.7 0.12 12.2 0.5 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-AN1 PF01428.11 OAP60298.1 - 2.1e-23 81.8 27.6 1.2e-11 44.3 7.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 OAP60298.1 - 0.00094 19.0 17.4 0.013 15.3 3.6 2.4 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 OAP60298.1 - 0.79 9.9 20.2 2.2 8.5 2.9 2.5 2 1 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.7 OAP60298.1 - 6.5 6.8 20.2 8.1 6.5 3.1 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain zf-RING_5 PF14634.1 OAP60298.1 - 9.2 6.0 20.5 1.5 8.6 1.5 2.5 2 0 0 2 2 2 0 zinc-RING finger domain Zn-ribbon_8 PF09723.5 OAP60298.1 - 9.9 6.2 10.9 2.7 8.0 0.9 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Thymidylat_synt PF00303.14 OAP60299.1 - 3e-113 377.3 0.0 3.4e-113 377.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Tyrosinase PF00264.15 OAP60301.1 - 3.7e-29 102.4 0.0 6.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Ank PF00023.25 OAP60302.1 - 4.9e-26 89.1 10.1 1.6e-07 30.7 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 OAP60302.1 - 3.4e-24 85.0 0.0 2.3e-14 53.4 0.1 4.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP60302.1 - 1.8e-15 56.5 6.4 0.00012 22.1 0.0 5.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP60302.1 - 2.4e-15 56.5 4.5 4e-10 39.9 0.0 5.1 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP60302.1 - 5.3e-14 50.9 4.1 0.0011 19.0 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat NACHT PF05729.7 OAP60302.1 - 3.7e-06 26.6 0.1 1.4e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP60302.1 - 2.5e-05 24.3 0.1 0.00011 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP60302.1 - 0.00056 20.0 0.0 0.0083 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 OAP60302.1 - 0.00074 19.4 0.0 0.0027 17.6 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP60302.1 - 0.0052 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 OAP60302.1 - 0.0098 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 OAP60302.1 - 0.018 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RNA_helicase PF00910.17 OAP60302.1 - 0.046 13.8 0.4 0.17 12.0 0.0 2.2 2 0 0 2 2 1 0 RNA helicase KAP_NTPase PF07693.9 OAP60302.1 - 0.06 12.3 0.2 0.55 9.1 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.17 OAP60302.1 - 0.1 11.4 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 OAP60302.1 - 0.16 11.6 0.1 0.54 9.9 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase FMN_dh PF01070.13 OAP60304.1 - 1.8e-115 385.6 0.0 2.3e-115 385.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 OAP60304.1 - 2.5e-05 23.3 0.1 4e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAP60304.1 - 0.00028 19.8 0.8 0.00077 18.4 0.1 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 OAP60304.1 - 0.00043 19.4 0.0 0.58 9.1 0.0 2.5 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 OAP60304.1 - 0.0032 16.6 0.7 0.0061 15.7 0.2 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 OAP60304.1 - 0.0034 16.6 0.4 0.32 10.2 0.0 3.0 2 1 2 4 4 4 1 Histidine biosynthesis protein IGPS PF00218.16 OAP60304.1 - 0.1 11.6 0.0 0.31 10.0 0.0 1.7 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Anoctamin PF04547.7 OAP60305.1 - 5e-120 401.2 1.3 5.9e-120 400.9 0.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel ABC_membrane PF00664.18 OAP60305.1 - 0.0011 18.4 0.0 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region F-box PF00646.28 OAP60306.1 - 4.2e-05 23.0 0.1 0.00011 21.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP60306.1 - 0.00032 20.3 0.2 0.00088 18.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like Na_Ca_ex PF01699.19 OAP60307.1 - 4.2e-31 107.4 22.8 1e-19 70.5 5.4 3.6 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 OAP60307.1 - 2.1e-10 40.8 14.5 2.1e-10 40.8 10.1 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF307) AAA PF00004.24 OAP60308.1 - 2.3e-44 150.7 0.0 3.6e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 OAP60308.1 - 1.7e-07 31.3 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAP60308.1 - 1.9e-07 30.8 0.0 4.7e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAP60308.1 - 1.3e-06 28.5 0.1 3.1e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAP60308.1 - 4.3e-06 26.8 0.1 0.00019 21.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP60308.1 - 4.7e-05 23.0 0.1 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 OAP60308.1 - 7.8e-05 23.4 0.0 0.00019 22.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAP60308.1 - 9.7e-05 21.5 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 OAP60308.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAP60308.1 - 0.001 17.9 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 OAP60308.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAP60308.1 - 0.0025 17.7 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAP60308.1 - 0.0025 16.9 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 OAP60308.1 - 0.0039 17.1 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 OAP60308.1 - 0.0045 16.5 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 OAP60308.1 - 0.0065 15.6 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 OAP60308.1 - 0.0066 15.5 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 OAP60308.1 - 0.015 14.7 0.1 0.075 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 OAP60308.1 - 0.015 15.5 0.0 0.049 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.8 OAP60308.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 OAP60308.1 - 0.017 14.3 0.0 0.052 12.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 OAP60308.1 - 0.019 14.4 0.0 0.086 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 OAP60308.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAP60308.1 - 0.033 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 OAP60308.1 - 0.049 13.6 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 OAP60308.1 - 0.05 13.2 0.0 0.37 10.4 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 OAP60308.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 OAP60308.1 - 0.092 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 OAP60308.1 - 0.094 12.6 0.1 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NTPase_1 PF03266.10 OAP60308.1 - 0.14 11.8 0.7 0.81 9.3 0.0 2.5 3 1 1 4 4 4 0 NTPase Inositol_P PF00459.20 OAP60309.1 - 7.7e-62 209.0 0.1 8.8e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family SKG6 PF08693.5 OAP60310.1 - 0.27 10.5 2.5 0.88 8.9 1.7 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pterin_4a PF01329.14 OAP60311.1 - 7.5e-10 38.4 0.0 1.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase ENT PF03735.9 OAP60311.1 - 0.02 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 ENT domain DUF123 PF01986.11 OAP60311.1 - 0.045 13.8 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF123 EFG_II PF14492.1 OAP60311.1 - 0.12 12.2 0.2 0.49 10.2 0.0 2.1 3 0 0 3 3 3 0 Elongation Factor G, domain II FA_hydroxylase PF04116.8 OAP60312.1 - 1.5e-16 60.7 19.5 1.5e-16 60.7 13.5 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.11 OAP60313.1 - 5e-46 157.0 49.4 1.9e-36 125.5 25.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.22 OAP60316.1 - 7.9e-07 28.9 1.2 3e-06 27.0 0.8 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP60316.1 - 8.8e-05 22.1 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1775 PF07987.6 OAP60316.1 - 0.065 13.0 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) p450 PF00067.17 OAP60317.1 - 7.6e-61 206.0 0.0 1e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ComX PF05952.7 OAP60317.1 - 0.011 15.1 0.3 0.031 13.7 0.1 1.8 2 0 0 2 2 2 0 Bacillus competence pheromone ComX PRC PF05239.11 OAP60317.1 - 0.12 12.2 0.1 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 PRC-barrel domain Ank_2 PF12796.2 OAP60319.1 - 1.4e-82 272.1 4.5 3.1e-16 59.5 0.0 6.8 4 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 OAP60319.1 - 1.8e-52 172.6 13.9 8.7e-05 22.1 0.0 15.8 16 0 0 16 16 16 13 Ankyrin repeat Ank_4 PF13637.1 OAP60319.1 - 4.9e-48 160.6 4.7 1.1e-07 32.1 0.0 11.3 5 4 6 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP60319.1 - 4.3e-45 147.2 3.6 0.0001 22.1 0.0 15.5 15 0 0 15 15 15 9 Ankyrin repeat Ank_5 PF13857.1 OAP60319.1 - 4.9e-43 144.1 8.6 2.8e-05 24.1 0.0 11.6 5 5 9 14 14 14 12 Ankyrin repeats (many copies) p450 PF00067.17 OAP60320.1 - 2e-34 118.9 0.0 1.5e-25 89.7 0.0 2.8 2 1 1 3 3 3 2 Cytochrome P450 adh_short PF00106.20 OAP60321.1 - 8.9e-21 74.5 0.1 5.7e-20 71.8 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP60321.1 - 2.8e-05 23.8 0.0 7.5e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.13 OAP60321.1 - 6.6e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 OAP60321.1 - 0.00024 20.6 0.0 0.00085 18.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAP60321.1 - 0.00078 19.2 0.0 0.0045 16.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DFP PF04127.10 OAP60321.1 - 0.0072 15.9 0.2 0.013 15.1 0.2 1.4 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Methyltransf_18 PF12847.2 OAP60321.1 - 0.025 15.1 0.0 0.04 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.8 OAP60321.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) FAD_binding_3 PF01494.14 OAP60321.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 OAP60321.1 - 0.13 12.2 0.1 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP60322.1 - 2.5e-17 63.6 0.0 4.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP60322.1 - 2.8e-07 29.1 0.0 2.9e-06 25.7 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 OAP60322.1 - 6.8e-07 29.4 0.6 0.0015 18.6 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 OAP60322.1 - 1.2e-05 25.2 0.0 3.6e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP60322.1 - 2e-05 24.5 0.1 0.025 14.4 0.0 3.3 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP60322.1 - 0.00019 20.4 0.0 0.021 13.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAP60322.1 - 0.00076 18.4 3.8 0.19 10.6 0.8 2.7 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP60322.1 - 0.0018 17.2 0.2 0.0031 16.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 OAP60322.1 - 0.011 14.9 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP60322.1 - 0.022 15.0 0.0 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 OAP60322.1 - 0.023 14.4 0.6 1.1 8.9 0.2 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAP60322.1 - 0.037 12.9 0.0 0.13 11.1 0.0 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 OAP60322.1 - 0.058 13.8 0.9 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 OAP60323.1 - 8.5e-14 51.0 53.0 6.3e-08 31.7 31.1 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 OAP60324.1 - 5.3e-69 232.9 0.0 6.5e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.1 OAP60325.1 - 1.9e-06 27.9 0.0 3.2e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP60325.1 - 0.00012 21.8 0.1 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP60325.1 - 0.00017 21.5 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF3970 PF13113.1 OAP60325.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) GST_N_3 PF13417.1 OAP60326.1 - 9.8e-07 28.9 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP60326.1 - 6.8e-05 22.6 0.6 0.00017 21.3 0.4 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP60326.1 - 0.00046 20.1 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP60326.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HET PF06985.6 OAP60327.1 - 5.7e-07 29.7 0.0 6.8e-05 23.0 0.0 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ammonium_transp PF00909.16 OAP60329.1 - 2.1e-106 355.7 32.2 2.6e-106 355.4 22.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UQ_con PF00179.21 OAP60330.1 - 2.1e-20 72.5 0.1 3.1e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP60330.1 - 0.0013 18.4 0.1 0.03 14.0 0.0 2.4 2 1 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 OAP60330.1 - 0.014 15.2 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 RWD domain MIF4G PF02854.14 OAP60331.1 - 4.9e-28 97.9 0.3 1e-27 96.9 0.1 1.6 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 OAP60331.1 - 3.2e-26 91.2 0.2 1.2e-25 89.3 0.0 2.1 2 0 0 2 2 2 1 MA3 domain DPM2 PF07297.7 OAP60332.1 - 2.4e-31 107.8 2.6 2.8e-31 107.6 1.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 OAP60332.1 - 2.3e-05 24.0 0.9 2.3e-05 24.0 0.7 1.1 1 0 0 1 1 1 1 PIG-P DUF4083 PF13314.1 OAP60332.1 - 0.0036 17.0 2.3 0.019 14.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) DUF4229 PF14012.1 OAP60332.1 - 0.0048 16.7 0.9 0.0048 16.7 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.1 OAP60332.1 - 0.032 13.8 0.1 0.032 13.8 0.1 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Baculo_p26 PF04766.7 OAP60333.1 - 0.035 13.3 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein PFK PF00365.15 OAP60334.1 - 1e-154 513.5 0.0 1.2e-114 382.0 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase CPSF_A PF03178.10 OAP60335.1 - 1.7e-85 286.9 0.0 5.6e-84 281.9 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region CTDII PF01556.13 OAP60335.1 - 0.15 11.9 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 DnaJ C terminal domain DUF2457 PF10446.4 OAP60335.1 - 0.87 8.2 4.4 2.3 6.8 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LMBR1 PF04791.11 OAP60336.1 - 6.7e-17 61.2 3.0 6.7e-17 61.2 2.1 2.4 1 1 1 2 2 2 1 LMBR1-like membrane protein DUF3357 PF11837.3 OAP60336.1 - 1.7 8.5 10.9 1.3e+02 2.4 0.2 5.8 6 1 1 7 7 7 0 Domain of unknown function (DUF3357) stn_TNFRSF12A PF12191.3 OAP60336.1 - 9 6.3 10.9 0.57 10.2 0.6 3.5 4 0 0 4 4 4 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TFIIA PF03153.8 OAP60337.1 - 0.023 14.6 4.4 0.034 14.0 3.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit X PF00739.14 OAP60338.1 - 0.18 11.6 2.1 0.31 10.9 1.5 1.4 1 0 0 1 1 1 0 Trans-activation protein X WD40 PF00400.27 OAP60339.1 - 1.3e-11 43.8 3.0 0.0024 17.6 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4611 PF15387.1 OAP60339.1 - 7.2 6.8 8.4 5 7.3 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Fungal_trans_2 PF11951.3 OAP60340.1 - 2.7e-11 42.7 3.1 3.8e-11 42.2 2.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain APG6 PF04111.7 OAP60341.1 - 6.9e-103 343.9 0.0 1.1e-102 343.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 AAA_28 PF13521.1 OAP60341.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrkA_N PF02254.13 OAP60341.1 - 0.04 13.9 0.1 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Scm3 PF10384.4 OAP60342.1 - 1e-18 66.5 0.1 2.3e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 PALP PF00291.20 OAP60343.1 - 1.4e-58 198.5 0.2 1.8e-58 198.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UPF0181 PF03701.9 OAP60343.1 - 0.039 13.2 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Methyltransf_28 PF02636.12 OAP60344.1 - 4.9e-37 127.6 0.0 7.3e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase P34-Arc PF04045.9 OAP60345.1 - 3.3e-104 347.4 0.5 4e-104 347.1 0.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 OAP60345.1 - 9.8e-05 21.8 1.5 0.00031 20.1 0.8 1.9 2 1 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) Hemerythrin PF01814.18 OAP60345.1 - 0.2 11.8 5.0 1.2 9.2 0.7 2.5 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain NAD_binding_1 PF00175.16 OAP60346.1 - 2.1e-14 53.9 0.0 4.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 OAP60346.1 - 1.6e-11 44.5 0.0 9.8e-11 41.9 0.0 2.2 3 0 0 3 3 3 1 Globin FAD_binding_6 PF00970.19 OAP60346.1 - 3.2e-09 36.7 0.0 5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 OAP60346.1 - 3.3e-07 30.0 0.1 5.8e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 OAP60346.1 - 2.2e-05 24.4 0.0 0.00058 19.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain MamL-1 PF09596.5 OAP60347.1 - 0.58 10.0 2.8 2 8.3 0.5 2.4 2 0 0 2 2 2 0 MamL-1 domain WD40 PF00400.27 OAP60348.1 - 4.1e-69 226.2 26.6 7.4e-09 35.1 0.0 13.0 13 1 0 13 13 13 11 WD domain, G-beta repeat Utp12 PF04003.7 OAP60348.1 - 1e-16 60.8 0.1 1.7e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 OAP60348.1 - 9.8e-05 21.2 3.7 0.51 9.0 0.0 4.4 3 1 1 5 5 5 2 Nup133 N terminal like Nup160 PF11715.3 OAP60348.1 - 0.0001 20.6 8.6 0.046 11.8 0.0 5.1 4 2 1 5 5 5 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 OAP60348.1 - 0.0018 16.6 0.9 0.026 12.7 0.0 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3312) eIF2A PF08662.6 OAP60348.1 - 0.0077 15.9 0.1 8.1 6.1 0.0 4.5 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Myb_DNA-binding PF00249.26 OAP60349.1 - 4.8e-24 84.1 1.8 1.4e-12 47.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAP60349.1 - 6.4e-21 74.2 1.5 1e-13 51.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_23 PF13384.1 OAP60349.1 - 0.033 13.8 0.4 0.09 12.4 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain DUF2774 PF11242.3 OAP60349.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Glyco_transf_41 PF13844.1 OAP60350.1 - 6.9e-91 304.5 1.6 8.4e-46 155.8 0.2 3.3 3 1 0 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 OAP60350.1 - 5.2e-19 67.6 16.2 3.9e-07 29.6 0.6 4.7 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 OAP60350.1 - 1e-16 59.7 9.9 7.3e-05 22.2 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAP60350.1 - 1.6e-16 58.7 10.8 0.00071 19.3 0.2 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAP60350.1 - 5.4e-13 48.6 13.0 1.1e-05 25.2 0.7 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP60350.1 - 7.3e-13 47.9 14.1 3.9e-05 23.9 1.0 5.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAP60350.1 - 4.3e-11 43.1 16.7 1.1e-05 25.9 0.5 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAP60350.1 - 1.9e-09 36.9 6.2 0.24 11.7 0.0 5.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAP60350.1 - 1.9e-08 33.4 2.6 0.67 9.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAP60350.1 - 2.4e-08 33.6 18.7 0.098 12.6 1.3 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAP60350.1 - 6.2e-08 31.8 5.1 0.1 12.4 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAP60350.1 - 1.6e-05 25.1 4.9 0.18 12.1 0.9 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 OAP60350.1 - 0.0011 19.0 4.6 0.15 12.2 0.2 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 OAP60350.1 - 0.0081 16.5 7.4 6 7.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.12 OAP60350.1 - 0.12 12.6 7.5 1.4 9.2 0.0 3.5 4 0 0 4 4 4 0 Bacterial transcriptional activator domain ADK PF00406.17 OAP60351.1 - 1.7e-35 122.1 0.0 9.8e-21 74.2 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 OAP60351.1 - 2.4e-13 49.4 0.0 3.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 OAP60351.1 - 2.6e-06 27.7 0.0 8.1e-06 26.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAP60351.1 - 0.00025 21.8 0.0 0.00092 20.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAP60351.1 - 0.0004 20.2 0.0 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 OAP60351.1 - 0.038 13.0 0.1 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 OAP60351.1 - 0.048 13.6 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain PH_11 PF15413.1 OAP60351.1 - 0.08 13.2 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain AAA_5 PF07728.9 OAP60351.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 OAP60351.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DNA_primase_lrg PF04104.9 OAP60352.1 - 1.2e-81 273.7 0.0 2.5e-81 272.7 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit DUF3533 PF12051.3 OAP60353.1 - 5e-85 285.5 14.2 7.3e-85 285.0 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Cys_Met_Meta_PP PF01053.15 OAP60354.1 - 1e-132 442.0 0.0 1.2e-132 441.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 OAP60354.1 - 1e-06 28.0 0.0 4.7e-06 25.8 0.1 2.0 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 OAP60354.1 - 1.1e-06 27.9 0.0 2.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAP60354.1 - 1.4e-05 24.1 0.0 2.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAP60354.1 - 1.5e-05 23.9 0.1 4.6e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 OAP60354.1 - 0.00054 18.3 0.0 0.00075 17.9 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 OAP60354.1 - 0.0021 16.5 0.0 0.0031 16.0 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) FAD-oxidase_C PF02913.14 OAP60354.1 - 0.0035 16.7 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain GDC-P PF02347.11 OAP60354.1 - 0.0069 15.1 0.0 0.0099 14.6 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein AA_kinase PF00696.23 OAP60355.1 - 1.5e-33 116.3 0.1 2.5e-33 115.6 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 OAP60355.1 - 7.4e-11 41.3 5.9 3.7e-09 35.8 0.3 2.9 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 OAP60355.1 - 1.3e-09 37.3 1.9 1.3e-09 37.3 1.3 2.2 2 0 0 2 2 2 1 ACT domain Abhydrolase_1 PF00561.15 OAP60356.1 - 4.3e-34 118.0 0.1 6.9e-34 117.3 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP60356.1 - 3.5e-13 49.9 0.0 6.4e-13 49.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 OAP60356.1 - 2.5e-05 24.0 0.0 5.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.2 OAP60356.1 - 0.0049 16.6 0.0 0.071 12.8 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family CN_hydrolase PF00795.17 OAP60357.1 - 2.8e-36 124.6 0.0 3.8e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Zn_clus PF00172.13 OAP60358.1 - 1e-07 31.7 10.9 1e-07 31.7 7.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP60358.1 - 6.9e-07 28.4 1.4 1.6e-06 27.1 1.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 OAP60359.1 - 2.7e-53 181.1 0.0 2.7e-52 177.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 OAP60360.1 - 1.6e-37 129.0 34.4 4e-37 127.7 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP60360.1 - 3.5e-12 45.6 28.5 4.1e-11 42.1 19.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter PUCC PF03209.10 OAP60360.1 - 0.00027 19.8 7.5 0.00027 19.8 5.2 2.5 2 1 1 3 3 3 1 PUCC protein Fungal_trans_2 PF11951.3 OAP60361.1 - 1.4e-52 178.6 0.9 1.6e-52 178.3 0.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60361.1 - 2e-07 30.7 12.0 4.2e-07 29.7 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 OAP60362.1 - 0.0002 20.5 1.3 0.00042 19.4 0.1 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Acetyltransf_1 PF00583.19 OAP60363.1 - 1.4e-07 31.3 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP60363.1 - 4.8e-07 29.8 0.0 9.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP60363.1 - 8.7e-06 25.6 0.0 0.0067 16.2 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP60363.1 - 0.00022 21.3 0.0 0.0029 17.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP60363.1 - 0.00053 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 OAP60363.1 - 0.08 13.0 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP60363.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase 2OG-FeII_Oxy PF03171.15 OAP60364.1 - 1.1e-13 51.3 0.0 2.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP60364.1 - 5e-13 49.6 0.0 8.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sugar_tr PF00083.19 OAP60365.1 - 6.1e-27 94.2 33.1 4.5e-20 71.6 5.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP60365.1 - 6e-18 64.6 40.8 4.7e-10 38.7 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 OAP60365.1 - 0.011 14.2 1.0 0.011 14.2 0.7 2.6 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like BT1 PF03092.11 OAP60365.1 - 0.05 12.2 2.9 0.24 10.0 0.7 2.3 2 1 0 2 2 2 0 BT1 family Pyr_redox_3 PF13738.1 OAP60367.1 - 3.1e-26 92.6 0.0 5.3e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP60367.1 - 2.4e-18 65.6 0.0 6.4e-16 57.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP60367.1 - 1.4e-12 47.3 0.0 2.9e-11 43.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP60367.1 - 8.5e-12 44.6 0.0 1.3e-09 37.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP60367.1 - 1.8e-08 34.4 0.0 1.3e-06 28.4 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP60367.1 - 2.9e-08 33.6 0.3 0.008 15.9 0.1 4.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 OAP60367.1 - 1.8e-07 30.3 0.0 0.0052 15.7 0.0 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP60367.1 - 0.00018 21.8 0.1 0.23 11.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP60367.1 - 0.00098 19.2 0.2 0.13 12.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 OAP60367.1 - 0.002 17.2 0.4 0.0064 15.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 OAP60367.1 - 0.015 14.2 0.0 0.39 9.5 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 OAP60367.1 - 0.077 13.2 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 OAP60367.1 - 0.18 11.7 0.2 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding Sugar_tr PF00083.19 OAP60368.1 - 7.3e-55 186.3 13.3 9.1e-55 186.0 9.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60368.1 - 6.8e-22 77.6 28.1 4.4e-21 74.9 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP60368.1 - 1.1e-05 24.1 20.3 0.025 13.0 1.6 3.3 2 2 1 3 3 3 3 MFS/sugar transport protein PhyH PF05721.8 OAP60369.1 - 2e-20 73.7 0.0 2.8e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease_2 PF13520.1 OAP60370.1 - 2.8e-52 177.7 54.5 3.3e-52 177.4 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP60370.1 - 2.1e-20 72.5 44.9 2.9e-20 72.0 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 OAP60371.1 - 3.7e-32 111.3 3.2 5.4e-32 110.8 2.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-Mss51 PF13824.1 OAP60373.1 - 5.1e-07 29.4 2.1 1.6e-06 27.8 1.5 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 OAP60373.1 - 1.1e-05 25.1 4.1 3.2e-05 23.7 2.8 1.8 1 0 0 1 1 1 1 MYND finger DUF3712 PF12505.3 OAP60374.1 - 2.2e-09 37.4 0.6 2.8e-07 30.5 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 OAP60374.1 - 4e-08 33.5 0.2 0.022 15.1 0.0 4.6 4 0 0 4 4 4 2 Late embryogenesis abundant protein SprA-related PF12118.3 OAP60374.1 - 0.038 13.3 22.9 0.052 12.8 15.9 1.2 1 0 0 1 1 1 0 SprA-related family UNC-50 PF05216.8 OAP60374.1 - 0.23 10.6 0.2 6.2 5.9 0.0 2.2 2 0 0 2 2 2 0 UNC-50 family DDHD PF02862.12 OAP60374.1 - 0.63 9.8 20.5 1.3 8.7 14.2 1.5 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.1 OAP60374.1 - 1.5 8.3 20.3 3.3 7.2 14.1 1.5 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.9 OAP60374.1 - 4.1 5.3 27.3 6 4.7 18.9 1.1 1 0 0 1 1 1 0 CDC45-like protein S-methyl_trans PF02574.11 OAP60375.1 - 8.8e-42 143.4 0.0 1e-41 143.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase OTCace PF00185.19 OAP60376.1 - 3.7e-40 137.3 0.0 5.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 OAP60376.1 - 7e-40 135.9 0.0 1e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF3984 PF13136.1 OAP60377.1 - 1.4e-29 103.3 29.4 1.9e-27 96.3 20.4 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) S1-P1_nuclease PF02265.11 OAP60378.1 - 1.5e-62 211.5 0.4 1.7e-62 211.3 0.3 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Nucleoporin_C PF03177.9 OAP60379.1 - 2.3e-56 191.5 0.6 2.1e-55 188.4 0.4 2.3 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 OAP60379.1 - 1.9e-50 171.8 0.0 2.5e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.10 OAP60380.1 - 0.0047 17.4 2.8 0.0093 16.4 1.9 1.5 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CIAPIN1 PF05093.8 OAP60381.1 - 1.1e-34 118.5 4.7 1.7e-34 117.8 3.3 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis ALAD PF00490.16 OAP60382.1 - 3.1e-117 391.0 0.0 3.7e-117 390.8 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Zn_clus PF00172.13 OAP60383.1 - 2.7e-09 36.7 11.5 5.4e-09 35.8 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ldl_recept_a PF00057.13 OAP60383.1 - 0.23 11.3 4.4 0.6 10.0 3.1 1.7 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A GRAB PF10375.4 OAP60384.1 - 7.5e-09 34.8 0.2 1.4e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CALCOCO1 PF07888.6 OAP60384.1 - 0.00012 20.5 39.5 0.00012 20.5 27.4 2.3 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 OAP60384.1 - 0.00039 19.7 15.3 0.0097 15.1 0.9 3.0 2 1 1 3 3 3 2 Reovirus sigma C capsid protein HALZ PF02183.13 OAP60384.1 - 0.025 14.3 1.1 0.025 14.3 0.8 5.5 5 3 1 7 7 7 0 Homeobox associated leucine zipper DUF3584 PF12128.3 OAP60384.1 - 0.3 8.3 53.5 0.074 10.3 13.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.1 OAP60384.1 - 0.9 8.4 42.3 1.6 7.6 15.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.16 OAP60384.1 - 2.2 7.6 52.7 0.34 10.3 3.6 2.9 1 1 2 3 3 3 0 Intermediate filament protein IncA PF04156.9 OAP60384.1 - 3.1 7.3 62.6 0.13 11.8 18.2 3.5 1 1 2 3 3 3 0 IncA protein DUF4239 PF14023.1 OAP60384.1 - 3.8 6.8 13.6 1.6 8.0 2.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) Tup_N PF08581.5 OAP60384.1 - 4.9 7.4 39.9 3.9 7.7 0.6 6.2 1 1 5 6 6 6 0 Tup N-terminal HAUS-augmin3 PF14932.1 OAP60384.1 - 5.9 6.0 47.9 2.2 7.3 11.8 2.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.7 OAP60384.1 - 9.2 6.0 24.3 0.2 11.4 0.7 4.0 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spindle_Spc25 PF08234.7 OAP60385.1 - 1.4e-07 31.3 0.0 4e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Chromosome segregation protein Spc25 Striatin PF08232.7 OAP60385.1 - 0.011 16.0 12.5 0.032 14.5 3.3 2.2 1 1 1 2 2 2 0 Striatin family HAP1_N PF04849.8 OAP60385.1 - 0.055 12.3 10.2 0.078 11.9 7.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region RasGAP_C PF03836.10 OAP60385.1 - 0.12 12.0 4.6 0.18 11.4 3.2 1.3 1 0 0 1 1 1 0 RasGAP C-terminus ADIP PF11559.3 OAP60385.1 - 0.13 12.1 17.0 0.21 11.4 7.3 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 OAP60385.1 - 0.43 10.6 5.7 0.69 10.0 3.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 OAP60385.1 - 0.51 10.7 10.6 0.12 12.8 3.1 2.5 1 1 1 2 2 2 0 SlyX GBP_C PF02841.9 OAP60385.1 - 0.51 9.4 11.8 0.73 8.9 8.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain BRE1 PF08647.6 OAP60385.1 - 0.63 10.0 9.5 1.1 9.3 6.6 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TBPIP PF07106.8 OAP60385.1 - 1 8.8 9.1 2.1 7.8 5.5 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 OAP60385.1 - 1.1 8.7 9.5 0.83 9.1 4.7 2.2 1 1 1 2 2 2 0 Septum formation initiator Cortex-I_coil PF09304.5 OAP60385.1 - 1.2 9.1 12.3 1.5 8.8 3.2 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil APG6 PF04111.7 OAP60385.1 - 1.3 7.9 11.1 2.5 7.0 0.1 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4407 PF14362.1 OAP60385.1 - 1.3 7.8 11.3 0.86 8.5 5.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 OAP60385.1 - 1.8 7.3 11.1 2.7 6.8 7.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 OAP60385.1 - 2.5 7.4 14.9 4 6.7 9.5 1.5 1 1 0 1 1 1 0 Intermediate filament protein DUF3373 PF11853.3 OAP60385.1 - 6.5 5.1 8.2 9.5 4.6 5.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Sigma70_ner PF04546.8 OAP60386.1 - 0.27 10.8 8.9 0.55 9.8 6.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Methyltransf_11 PF08241.7 OAP60387.1 - 1.9e-07 31.4 0.0 5.2e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP60387.1 - 2.4e-06 26.8 0.0 3.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 OAP60387.1 - 5.5e-06 26.1 0.0 9.7e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP60387.1 - 1.1e-05 25.8 0.0 2.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP60387.1 - 2.8e-05 23.7 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP60387.1 - 3.4e-05 24.1 0.0 0.0001 22.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP60387.1 - 0.00036 21.0 0.0 0.0015 19.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain cobW PF02492.14 OAP60388.1 - 4.9e-44 149.8 2.0 3e-32 111.5 0.2 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 OAP60388.1 - 4.9e-18 64.6 0.2 2.2e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.1 OAP60388.1 - 0.015 14.7 0.2 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 OAP60388.1 - 0.022 13.6 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 OAP60388.1 - 0.032 14.1 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 OAP60388.1 - 0.032 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 OAP60388.1 - 0.043 13.8 0.2 0.17 11.8 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 OAP60388.1 - 0.051 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase UPF0079 PF02367.12 OAP60388.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 OAP60388.1 - 0.08 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAP60388.1 - 0.086 12.5 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain CDC45 PF02724.9 OAP60388.1 - 0.28 9.1 2.7 0.41 8.6 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_18 PF13238.1 OAP60388.1 - 0.33 11.2 3.5 0.46 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain adh_short PF00106.20 OAP60389.1 - 2.2e-20 73.2 0.9 5.9e-20 71.8 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60389.1 - 1.1e-15 58.0 0.9 1.9e-15 57.3 0.1 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP60389.1 - 9.6e-10 38.4 1.0 1.8e-08 34.2 0.1 2.2 2 0 0 2 2 2 1 KR domain DUF2650 PF10853.3 OAP60389.1 - 0.066 12.6 7.6 0.19 11.2 5.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) TPR_11 PF13414.1 OAP60390.1 - 3e-22 78.0 4.4 1.8e-18 65.9 2.0 2.5 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAP60390.1 - 1e-14 53.1 4.8 3.1e-05 23.5 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAP60390.1 - 4.9e-13 48.0 5.2 0.00033 20.1 0.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAP60390.1 - 5.4e-10 39.6 10.7 2e-06 28.3 0.7 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAP60390.1 - 9.1e-08 31.3 0.4 0.031 14.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP60390.1 - 3.9e-07 30.1 3.0 0.0026 18.2 0.5 3.8 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAP60390.1 - 5.6e-07 29.2 3.3 0.0027 17.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAP60390.1 - 0.00018 21.4 3.1 0.0087 15.9 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAP60390.1 - 0.0002 21.1 1.1 0.034 14.0 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP60390.1 - 0.00027 21.2 4.2 0.00046 20.4 0.4 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAP60390.1 - 0.0008 19.0 5.1 1.5 8.7 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat XPC-binding PF09280.6 OAP60390.1 - 0.0028 17.0 1.8 0.0028 17.0 1.3 2.5 2 0 0 2 2 2 1 XPC-binding domain BTAD PF03704.12 OAP60390.1 - 0.0044 17.3 0.6 0.075 13.3 0.1 2.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 OAP60390.1 - 0.022 13.8 0.9 0.037 13.0 0.6 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP60390.1 - 0.024 15.0 7.1 1.6 9.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 OAP60390.1 - 0.18 11.9 1.0 35 4.6 0.4 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 OAP60390.1 - 0.2 11.7 0.1 0.2 11.7 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) Peptidase_S28 PF05577.7 OAP60391.1 - 1.3e-35 122.8 0.0 1.7e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 OAP60391.1 - 0.00074 18.8 0.1 0.002 17.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAP60391.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PBP PF01161.15 OAP60394.1 - 3.3e-15 56.1 0.0 6.2e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GKAP PF03359.8 OAP60394.1 - 0.99 8.9 8.5 1.4 8.4 5.9 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein DUF3633 PF12315.3 OAP60394.1 - 1.1 8.4 2.6 1.5 8.0 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3633) DNA_pol_viral_N PF00242.12 OAP60394.1 - 2.7 6.9 8.0 3.4 6.5 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF572 PF04502.8 OAP60394.1 - 7.2 5.7 6.1 9.3 5.3 4.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAF-AH_p_II PF03403.8 OAP60397.1 - 1.1e-07 30.5 0.0 1.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 OAP60397.1 - 8.5e-07 28.8 0.1 1.2e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP60397.1 - 9e-06 25.7 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP60397.1 - 2.3e-05 24.0 0.0 2.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 OAP60397.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 OAP60397.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mit_ribos_Mrp51 PF11709.3 OAP60398.1 - 1.7e-55 188.4 0.0 2.5e-36 125.4 0.5 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 OAP60399.1 - 2.1e-58 195.4 0.3 2.5e-58 195.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 OAP60399.1 - 0.0067 17.1 0.1 0.0093 16.6 0.0 1.2 1 0 0 1 1 1 1 Blue/Ultraviolet sensing protein C terminal Thioredoxin PF00085.15 OAP60400.1 - 1.2e-45 153.4 0.0 2.4e-24 84.9 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 OAP60400.1 - 3.4e-15 56.3 0.0 0.0014 18.4 0.0 4.1 3 1 1 4 4 4 3 Thioredoxin-like domain HyaE PF07449.6 OAP60400.1 - 3.4e-05 23.6 0.0 0.5 10.2 0.0 3.9 4 0 0 4 4 4 2 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.1 OAP60400.1 - 4.5e-05 23.6 1.4 0.24 11.5 0.0 4.4 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAP60400.1 - 4.6e-05 23.4 0.2 0.13 12.4 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 OAP60400.1 - 0.024 14.6 2.1 0.53 10.3 0.0 3.5 4 0 0 4 4 4 0 Thioredoxin-like Thioredoxin_3 PF13192.1 OAP60400.1 - 0.16 11.8 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain Trypsin_2 PF13365.1 OAP60401.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain E1_DerP2_DerF2 PF02221.10 OAP60402.1 - 1.5e-23 83.4 0.7 1.8e-23 83.2 0.5 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 OAP60402.1 - 0.00077 19.4 0.1 0.0023 17.9 0.1 1.7 1 1 0 1 1 1 1 ML-like domain Amidohydro_2 PF04909.9 OAP60403.1 - 9.8e-20 71.2 0.1 1.2e-19 70.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 OAP60404.1 - 1.5e-26 92.9 30.1 1.5e-26 92.9 20.8 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.11 OAP60404.1 - 0.0025 16.5 0.3 0.0025 16.5 0.2 2.5 2 1 1 3 3 3 1 BT1 family PDGLE PF13190.1 OAP60404.1 - 0.011 15.3 0.0 0.042 13.5 0.0 2.1 1 0 0 1 1 1 0 PDGLE domain DUF1201 PF06716.6 OAP60404.1 - 1.1 9.1 11.8 0.11 12.2 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) HATPase_c PF02518.21 OAP60405.1 - 6e-21 74.2 0.2 1.1e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP60405.1 - 3.2e-20 72.2 0.0 7.3e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 OAP60405.1 - 1.6e-13 50.4 0.0 4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ETC_C1_NDUFA5 PF04716.9 OAP60406.1 - 2.8e-21 74.7 1.6 2.8e-21 74.7 1.1 2.1 2 0 0 2 2 2 1 ETC complex I subunit conserved region QCR10 PF09796.4 OAP60407.1 - 4.6e-28 96.6 0.1 6.5e-28 96.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Acetyltransf_3 PF13302.1 OAP60408.1 - 6.3e-19 68.5 0.0 9.3e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP60408.1 - 2.9e-13 50.0 0.0 3.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP60408.1 - 1.9e-09 37.3 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 OAP60408.1 - 1.5e-06 28.1 0.0 3e-06 27.1 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain ATP-synt_F PF01990.12 OAP60409.1 - 2.9e-32 110.9 0.1 3.4e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF1086 PF06461.6 OAP60409.1 - 0.063 13.0 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) PDT PF00800.13 OAP60409.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.4 1 1 1 2 2 2 0 Prephenate dehydratase DUF2418 PF10332.4 OAP60410.1 - 1.1e-32 112.2 2.0 2.7e-32 111.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) DUF4534 PF15049.1 OAP60410.1 - 0.62 9.6 0.2 1.6 8.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) Fungal_trans PF04082.13 OAP60411.1 - 3.9e-11 42.3 3.6 7.5e-11 41.3 2.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 OAP60412.1 - 3e-73 246.6 0.1 1.6e-72 244.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP60412.1 - 3.8e-12 46.9 0.1 7.9e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2376 PF09550.5 OAP60412.1 - 0.032 14.3 0.5 3.2 7.9 0.0 3.1 2 0 0 2 2 2 0 Conserved hypothetical phage protein (DUF2376) adh_short PF00106.20 OAP60413.1 - 2.1e-23 83.0 0.5 2.3e-22 79.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60413.1 - 1.1e-21 77.7 0.0 1.4e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP60413.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 OAP60413.1 - 0.029 14.3 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain TPP_enzyme_C PF02775.16 OAP60413.1 - 0.039 13.5 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2089 PF09862.4 OAP60413.1 - 0.11 12.3 0.0 0.79 9.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2089) HET PF06985.6 OAP60414.1 - 3.4e-07 30.5 1.2 0.00038 20.6 0.0 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF1819 PF08849.6 OAP60414.1 - 0.16 11.3 0.1 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) HET PF06985.6 OAP60415.1 - 1.2e-11 44.9 1.9 3.1e-08 33.8 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 OAP60416.1 - 2.7e-32 111.8 25.1 3.7e-32 111.4 17.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ILVD_EDD PF00920.16 OAP60417.1 - 1.1e-193 644.4 0.8 1.3e-193 644.2 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans PF04082.13 OAP60418.1 - 1.5e-20 73.1 3.1 1.1e-19 70.3 1.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain YusW PF14039.1 OAP60419.1 - 0.025 14.8 0.4 0.037 14.3 0.3 1.2 1 0 0 1 1 1 0 YusW-like protein BsuPI PF12690.2 OAP60419.1 - 0.092 12.4 0.1 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 Intracellular proteinase inhibitor T2SM PF04612.7 OAP60419.1 - 0.54 10.0 3.6 0.56 9.9 1.8 1.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M zinc-ribbons_6 PF07191.7 OAP60420.1 - 0.02 14.6 1.1 0.024 14.4 0.8 1.1 1 0 0 1 1 1 0 zinc-ribbons Cytochrom_c3_2 PF14537.1 OAP60420.1 - 0.097 13.0 0.6 0.11 12.8 0.4 1.1 1 0 0 1 1 1 0 Cytochrome c3 DUF1752 PF08550.5 OAP60421.1 - 0.012 15.1 0.4 0.023 14.2 0.3 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) zf-C2H2 PF00096.21 OAP60422.1 - 6.8e-09 35.5 18.0 5.4e-05 23.2 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 OAP60422.1 - 1.2e-08 34.1 0.6 3.5e-08 32.6 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 OAP60422.1 - 1.3e-08 34.7 16.5 6.1e-08 32.5 4.5 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP60422.1 - 1.3e-08 34.5 16.7 0.00013 22.0 0.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 OAP60422.1 - 0.00032 20.7 7.8 0.042 14.0 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAP60422.1 - 0.015 15.4 7.3 1.3 9.2 1.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAP60422.1 - 0.14 12.0 11.5 0.85 9.6 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 OAP60422.1 - 0.71 9.6 8.7 0.27 10.9 0.4 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 OAP60422.1 - 5.1 6.9 7.4 3 7.6 2.3 2.3 1 1 1 2 2 2 0 BED zinc finger p450 PF00067.17 OAP60423.1 - 9.2e-77 258.5 0.0 1.2e-76 258.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.8 OAP60424.1 - 7.1e-49 166.5 22.5 9.2e-49 166.1 15.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP60424.1 - 8.5e-25 87.1 42.5 8.5e-25 87.1 29.4 2.8 2 2 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP60424.1 - 7.5e-12 44.5 12.3 7.5e-12 44.5 8.5 4.1 3 2 1 4 4 4 2 Sugar (and other) transporter COesterase PF00135.23 OAP60425.1 - 1.6e-78 264.7 0.1 2e-78 264.4 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP60425.1 - 8.9e-07 28.6 0.4 9.9e-06 25.2 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold NmrA PF05368.8 OAP60426.1 - 1.3e-29 103.0 0.0 1.7e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP60426.1 - 1.9e-05 24.7 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAP60426.1 - 0.063 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 OAP60426.1 - 0.084 11.5 0.0 0.13 10.9 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP60426.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 OAP60427.1 - 5.7e-43 146.9 34.5 5.7e-43 146.9 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP60427.1 - 3.6e-11 42.3 24.3 7.3e-10 37.9 16.9 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 OAP60427.1 - 4.9e-10 38.2 0.8 4.9e-10 38.2 0.5 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CBM_14 PF01607.19 OAP60428.1 - 7.9e-09 35.3 4.2 9.7e-09 35.0 2.3 1.6 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Rootletin PF15035.1 OAP60430.1 - 0.0029 17.6 14.2 0.0055 16.7 9.8 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CorA PF01544.13 OAP60430.1 - 6.4 5.7 8.5 14 4.6 5.9 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.10 OAP60430.1 - 7.2 6.1 14.0 2 7.9 2.2 2.5 1 1 1 2 2 2 0 Septum formation initiator DHO_dh PF01180.16 OAP60431.1 - 5.8e-70 235.5 0.2 6e-58 196.1 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 OAP60431.1 - 0.00092 18.5 0.1 1.3 8.2 0.1 2.4 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 OAP60431.1 - 0.0074 15.1 0.0 0.41 9.4 0.0 2.7 3 0 0 3 3 3 1 FMN-dependent dehydrogenase NOGCT PF08155.6 OAP60432.1 - 1.3e-27 95.1 2.3 2.6e-27 94.2 1.6 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 OAP60432.1 - 1.2e-26 92.2 0.3 2.7e-26 91.1 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 OAP60432.1 - 3.7e-15 55.8 0.0 7.8e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP60432.1 - 1.1e-07 31.2 0.1 2.5e-07 30.0 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 OAP60432.1 - 0.00026 21.4 0.0 0.00078 19.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 OAP60432.1 - 0.0018 17.4 1.5 0.0031 16.6 0.1 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 OAP60432.1 - 0.014 15.2 0.0 4.6 7.0 0.0 2.6 1 1 1 2 2 2 0 Dynamin family AAA_14 PF13173.1 OAP60432.1 - 0.077 12.9 0.2 0.88 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain ADH_N PF08240.7 OAP60433.1 - 2.5e-08 33.6 0.0 4.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP60433.1 - 1.3e-07 31.1 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 OAP60437.1 - 3.3e-10 39.2 3.1 5.3e-10 38.6 2.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60437.1 - 2.2e-08 33.8 7.4 4e-08 33.0 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Got1 PF04178.7 OAP60438.1 - 4.2e-18 65.5 14.9 5.2e-18 65.2 10.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 OAP60438.1 - 0.3 10.7 9.4 0.043 13.4 2.6 2.3 2 0 0 2 2 2 0 YrhK-like protein DUF3353 PF11833.3 OAP60438.1 - 0.96 8.8 2.9 1.1 8.7 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Fungal_trans PF04082.13 OAP60439.1 - 1.4e-15 56.9 4.6 3.1e-15 55.7 0.2 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain End_N_terminal PF12218.3 OAP60439.1 - 0.079 12.4 0.0 0.64 9.5 0.0 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Glyoxalase PF00903.20 OAP60440.1 - 1.3e-23 83.3 0.6 2.5e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 OAP60440.1 - 6.6e-16 58.2 0.3 5.9e-07 29.4 0.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP60440.1 - 2.6e-10 40.8 0.1 0.00026 21.5 0.0 2.7 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 OAP60440.1 - 3e-06 27.2 0.2 0.42 10.4 0.0 4.0 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 OAP60440.1 - 7.2e-06 25.9 0.3 0.0002 21.3 0.2 2.5 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_11 PF13414.1 OAP60441.1 - 0.00015 21.3 0.1 0.00053 19.5 0.0 2.0 1 1 1 2 2 2 1 TPR repeat FMO-like PF00743.14 OAP60442.1 - 1.5e-49 168.6 0.0 2.1e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAP60442.1 - 1.3e-20 74.3 0.0 3e-20 73.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP60442.1 - 9.6e-05 22.3 0.0 0.00032 20.6 0.0 1.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP60442.1 - 0.00091 19.0 0.0 0.0049 16.6 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAP60442.1 - 0.0073 16.3 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP60442.1 - 0.0085 15.0 0.0 0.041 12.7 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAP60442.1 - 0.013 14.6 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 OAP60442.1 - 0.045 12.2 0.0 1.9 6.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 OAP60442.1 - 0.059 12.4 0.2 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 OAP60442.1 - 0.088 13.2 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Snf7 PF03357.16 OAP60443.1 - 1e-17 64.0 7.1 1.5e-17 63.5 4.9 1.2 1 0 0 1 1 1 1 Snf7 Mmp37 PF09139.6 OAP60443.1 - 0.067 12.2 1.6 0.11 11.5 1.1 1.3 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Anp1 PF03452.9 OAP60443.1 - 0.072 12.2 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Anp1 REV PF00424.13 OAP60443.1 - 0.27 11.1 3.9 0.3 11.0 0.7 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) GrpE PF01025.14 OAP60443.1 - 0.97 8.9 4.9 0.33 10.4 1.3 1.7 2 0 0 2 2 2 0 GrpE Amidase PF01425.16 OAP60444.1 - 2.8e-92 309.8 0.0 4.2e-92 309.2 0.0 1.3 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 OAP60445.1 - 2.3e-11 42.9 0.3 2.9e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.17 OAP60446.1 - 3.3e-63 214.2 0.3 5.1e-63 213.6 0.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Aminotran_1_2 PF00155.16 OAP60447.1 - 1.1e-39 136.4 0.0 8.4e-33 113.7 0.0 2.9 3 0 0 3 3 3 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAP60447.1 - 0.025 13.7 0.0 0.066 12.3 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DUF3471 PF11954.3 OAP60449.1 - 0.092 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Na_Ca_ex PF01699.19 OAP60450.1 - 3.5e-31 107.6 32.5 2.9e-18 65.8 9.7 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Peptidase_S10 PF00450.17 OAP60451.1 - 4.4e-80 269.8 0.0 5.2e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CoA_trans PF01144.18 OAP60452.1 - 6.3e-90 300.1 3.7 1.1e-48 165.2 0.0 3.1 3 0 0 3 3 3 3 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 OAP60452.1 - 0.00013 21.6 0.2 0.0004 20.0 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain TauD PF02668.11 OAP60453.1 - 2.6e-49 168.2 0.3 3e-49 168.0 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 OAP60454.1 - 4.5e-30 104.5 32.2 4.5e-30 104.5 22.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Actin PF00022.14 OAP60455.1 - 5.2e-22 77.8 0.0 6.8e-19 67.5 0.0 2.8 3 0 0 3 3 3 2 Actin Podoplanin PF05808.6 OAP60455.1 - 0.62 9.6 3.0 0.38 10.2 0.6 1.8 1 1 0 1 1 1 0 Podoplanin Pkinase PF00069.20 OAP60456.1 - 5.2e-14 52.0 0.0 1.1e-13 50.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP60456.1 - 9.9e-13 47.7 0.0 5.2e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase bZIP_2 PF07716.10 OAP60457.1 - 8.3e-06 25.5 17.5 2.2e-05 24.2 12.1 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 OAP60457.1 - 2.3e-05 24.2 15.9 4.9e-05 23.2 11.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor Arv1 PF04161.8 OAP60459.1 - 2.9e-43 148.1 0.0 4.5e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Arv1-like family MFS_1 PF07690.11 OAP60460.1 - 1.1e-29 103.2 50.9 2e-27 95.8 10.1 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP60460.1 - 1.3e-10 40.1 10.0 2.9e-10 39.0 6.9 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage-MuB_C PF09077.6 OAP60460.1 - 0.0076 15.8 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Mu B transposition protein, C terminal FHIPEP PF00771.15 OAP60460.1 - 0.17 10.1 0.1 0.28 9.4 0.1 1.2 1 0 0 1 1 1 0 FHIPEP family DUF2611 PF11022.3 OAP60460.1 - 1 9.4 5.8 25 5.0 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2611) DUF619 PF04768.8 OAP60461.1 - 1.3e-51 174.4 0.0 9e-51 171.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF619) DUF4404 PF14357.1 OAP60461.1 - 0.77 10.2 6.9 1.3 9.4 0.1 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) NAD_binding_2 PF03446.10 OAP60462.1 - 2.7e-31 108.6 0.1 4.1e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAP60462.1 - 8.2e-14 51.8 0.1 2.6e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 OAP60462.1 - 1e-09 38.4 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 OAP60462.1 - 2.5e-08 34.0 0.0 4.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 OAP60462.1 - 8.8e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain GFO_IDH_MocA PF01408.17 OAP60462.1 - 0.011 16.3 0.1 0.044 14.3 0.0 2.0 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold PDH PF02153.12 OAP60462.1 - 0.04 12.7 0.1 0.06 12.2 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase IlvN PF07991.7 OAP60462.1 - 0.041 13.2 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Glyco_tran_WecB PF03808.8 OAP60462.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family UDPG_MGDP_dh_N PF03721.9 OAP60462.1 - 0.07 12.5 0.3 0.28 10.5 0.2 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ham1p_like PF01725.11 OAP60462.1 - 0.11 11.8 0.0 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 Ham1 family FAD_binding_3 PF01494.14 OAP60463.1 - 1.2e-30 106.7 0.0 3e-30 105.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP60463.1 - 4.2e-05 22.6 0.0 0.0014 17.6 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein SE PF08491.5 OAP60463.1 - 0.00013 20.8 0.0 0.00032 19.6 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 OAP60463.1 - 0.0003 21.1 0.6 1 9.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP60463.1 - 0.00038 20.4 0.8 0.00091 19.2 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP60463.1 - 0.0011 17.9 3.2 0.25 10.2 0.5 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP60463.1 - 0.0012 18.9 0.0 0.004 17.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP60463.1 - 0.0089 15.9 0.2 0.029 14.2 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP60463.1 - 0.011 14.6 2.7 0.034 13.0 1.8 2.2 1 1 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 OAP60463.1 - 0.067 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.9 OAP60463.1 - 0.64 8.4 2.0 9.5 4.5 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein TPR_12 PF13424.1 OAP60464.1 - 8.8e-16 57.6 4.5 2.2e-09 37.0 1.3 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat Clr5 PF14420.1 OAP60464.1 - 1.3e-14 53.8 0.7 3e-14 52.6 0.1 2.0 2 0 0 2 2 2 1 Clr5 domain TPR_10 PF13374.1 OAP60464.1 - 2.2e-11 43.3 7.6 0.00078 19.2 0.4 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAP60464.1 - 4.5e-05 24.0 8.6 0.00039 21.0 1.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP60464.1 - 0.00053 20.2 0.2 0.003 17.8 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAP60464.1 - 0.0013 18.3 1.4 0.041 13.6 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAP60464.1 - 0.017 15.4 8.9 4.3 8.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP60464.1 - 0.02 15.5 14.9 1.2 9.9 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP60464.1 - 0.078 12.9 1.9 11 6.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PAT1 PF09770.4 OAP60465.1 - 4.5 5.3 23.6 5.2 5.1 16.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_31 PF01055.21 OAP60466.1 - 1.8e-170 567.5 3.5 2.3e-170 567.1 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 OAP60466.1 - 1.1e-10 41.2 1.5 4.5e-10 39.2 0.8 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Amidase PF01425.16 OAP60467.1 - 9.9e-78 261.9 1.7 1.3e-77 261.5 1.2 1.1 1 0 0 1 1 1 1 Amidase Glyco_transf_28 PF03033.15 OAP60468.1 - 2.6e-19 69.3 0.0 1.8e-18 66.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 OAP60468.1 - 2.5e-06 26.3 0.0 4.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 OAP60468.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.6 3 1 1 4 4 4 0 Glycosyltransferase family 28 C-terminal domain UIM PF02809.15 OAP60468.1 - 0.8 9.4 17.8 1.7 8.3 0.5 4.8 5 0 0 5 5 5 0 Ubiquitin interaction motif adh_short PF00106.20 OAP60469.1 - 4e-19 69.1 0.1 8.4e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_deac_1 PF01522.16 OAP60469.1 - 1.9e-16 59.8 0.0 4e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase adh_short_C2 PF13561.1 OAP60469.1 - 8.3e-15 55.2 0.0 1.3e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP60469.1 - 1.8e-05 24.4 0.0 4.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP60469.1 - 8.3e-05 22.1 0.0 0.00083 18.8 0.0 2.3 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family DUF2334 PF10096.4 OAP60469.1 - 0.0023 17.4 0.0 0.006 16.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) NAD_binding_10 PF13460.1 OAP60469.1 - 0.0031 17.5 0.1 0.0087 16.0 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP60469.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 OAP60469.1 - 0.034 13.3 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family AA_permease_2 PF13520.1 OAP60470.1 - 5e-50 170.2 46.3 5.8e-50 170.0 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP60470.1 - 3.6e-25 88.2 40.9 5.1e-25 87.7 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.6 OAP60470.1 - 0.00022 21.0 1.9 0.002 17.9 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF962) Ribosomal_S7 PF00177.16 OAP60471.1 - 2.8e-39 134.0 1.8 3.4e-39 133.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Zn_clus PF00172.13 OAP60472.1 - 0.0013 18.5 3.5 0.0029 17.4 2.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SDA1 PF05285.7 OAP60473.1 - 1.7e-89 300.3 35.8 1.7e-89 300.3 24.8 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 OAP60473.1 - 5.1e-23 81.1 0.0 1.6e-22 79.5 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain RNR_inhib PF08591.5 OAP60475.1 - 2.9e-12 47.3 3.8 6.2e-12 46.2 0.3 2.5 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor HET PF06985.6 OAP60476.1 - 0.00069 19.7 0.3 0.0018 18.4 0.2 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GAS PF13851.1 OAP60477.1 - 0.56 9.3 27.2 0.83 8.8 7.5 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 OAP60477.1 - 2 6.9 17.8 5.2 5.6 12.3 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein Ank_2 PF12796.2 OAP60478.1 - 3.2e-13 49.8 0.9 2.2e-12 47.1 0.3 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAP60478.1 - 2.9e-08 33.1 4.6 5.2e-06 26.0 0.1 3.9 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 OAP60478.1 - 2.5e-07 30.7 6.3 0.00062 19.9 0.1 3.8 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP60478.1 - 2.3e-05 24.2 3.8 0.0036 17.4 0.1 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 OAP60478.1 - 5.6e-05 23.5 2.3 0.001 19.5 0.3 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Corona_S1 PF01600.11 OAP60478.1 - 0.13 10.5 0.0 0.21 9.8 0.0 1.2 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein PNP_UDP_1 PF01048.15 OAP60479.1 - 1.4e-13 50.4 0.4 4.9e-13 48.6 0.3 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily AIG2 PF06094.7 OAP60480.1 - 0.0027 18.1 0.0 0.0058 17.0 0.0 1.8 1 1 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 OAP60480.1 - 0.043 13.9 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 AIG2-like family Transferase PF02458.10 OAP60481.1 - 2.7e-24 85.4 0.0 1.7e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Transferase family BTB PF00651.26 OAP60482.1 - 9.7e-13 48.0 0.0 3.1e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain BTB_2 PF02214.17 OAP60482.1 - 0.047 13.8 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain DUF2023 PF09633.5 OAP60482.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2023) HIT PF01230.18 OAP60483.1 - 3.3e-21 75.6 0.0 5e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAP60483.1 - 1.2e-05 25.5 0.0 1.8e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 OAP60483.1 - 0.00046 19.8 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.12 OAP60483.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.4 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Nbs1_C PF08599.5 OAP60483.1 - 0.17 11.8 0.6 0.25 11.2 0.4 1.3 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 HD_3 PF13023.1 OAP60484.1 - 1e-43 148.9 0.0 1.4e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 OAP60484.1 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 HD domain Cytochrom_B561 PF03188.11 OAP60485.1 - 2.6e-08 33.7 9.7 6.3e-08 32.5 6.7 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2306 PF10067.4 OAP60485.1 - 0.00011 22.3 0.1 0.00011 22.3 0.1 2.7 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF373 PF04123.8 OAP60485.1 - 0.00011 21.3 1.6 0.00015 20.8 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF373) PepSY_TM_1 PF13172.1 OAP60485.1 - 0.002 17.8 0.2 0.002 17.8 0.1 4.1 4 1 0 4 4 4 1 PepSY-associated TM helix DUF347 PF03988.7 OAP60485.1 - 0.033 14.0 2.0 1.7 8.5 0.0 3.2 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) TraQ PF09679.5 OAP60485.1 - 0.097 12.6 4.2 1.4 8.8 0.5 3.5 2 1 2 4 4 4 0 Type-F conjugative transfer system pilin chaperone (TraQ) EphA2_TM PF14575.1 OAP60485.1 - 0.7 10.3 0.0 0.7 10.3 0.0 2.9 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain MFS_1 PF07690.11 OAP60485.1 - 2.1 7.0 15.9 3.6 6.1 5.9 2.6 1 1 0 2 2 2 0 Major Facilitator Superfamily Cytochrom_B_N PF00033.14 OAP60485.1 - 2.2 7.6 15.9 1.5e+02 1.6 0.0 3.1 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF1634 PF07843.6 OAP60485.1 - 2.6 7.7 7.5 0.23 11.1 0.6 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF1634) DUF4079 PF13301.1 OAP60485.1 - 3.5 7.6 17.0 0.49 10.3 0.3 3.5 2 1 0 4 4 4 0 Protein of unknown function (DUF4079) HET PF06985.6 OAP60486.1 - 1.8e-32 112.3 0.1 3.3e-32 111.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAUS6_N PF14661.1 OAP60487.1 - 3.9e-36 124.6 0.3 1.3e-35 122.9 0.1 1.9 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Vir_act_alpha_C PF10400.4 OAP60487.1 - 0.0039 17.5 0.6 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 Virulence activator alpha C-term HrpB2 PF09487.5 OAP60487.1 - 0.048 13.8 0.1 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) FAD_binding_2 PF00890.19 OAP60489.1 - 2.2e-59 201.3 0.6 2.7e-59 201.0 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP60489.1 - 3.8e-11 42.4 0.4 9.3e-10 37.9 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP60489.1 - 6.1e-08 32.5 0.4 3.2e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAP60489.1 - 3.4e-06 26.3 1.2 1.2e-05 24.5 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 OAP60489.1 - 4.1e-06 26.1 0.1 8.6e-06 25.0 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP60489.1 - 6e-06 25.5 0.8 0.00039 19.6 0.2 2.6 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 OAP60489.1 - 8.7e-06 25.7 0.7 0.00022 21.1 0.1 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP60489.1 - 1e-05 25.8 0.2 0.0014 18.9 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP60489.1 - 1.1e-05 25.6 0.0 5.1e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP60489.1 - 1.6e-05 24.0 0.8 0.0013 17.7 0.0 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 OAP60489.1 - 0.0008 17.9 2.2 0.01 14.3 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 OAP60489.1 - 0.0062 15.6 0.0 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 OAP60489.1 - 0.027 14.0 0.3 0.065 12.8 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fis1_TPR_C PF14853.1 OAP60491.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat HET PF06985.6 OAP60492.1 - 2.8e-26 92.3 0.5 4.6e-26 91.6 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.13 OAP60493.1 - 9.4e-08 31.8 8.5 9.4e-08 31.8 5.9 1.8 2 0 0 2 2 2 1 MYND finger SET PF00856.23 OAP60493.1 - 1.8e-06 28.3 0.0 1e-05 25.9 0.0 2.2 1 1 0 1 1 1 1 SET domain Alpha-amylase PF00128.19 OAP60494.1 - 1.4e-37 129.8 0.0 2.5e-36 125.6 0.0 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 OAP60494.1 - 0.0013 18.7 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.1 OAP60494.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme adh_short_C2 PF13561.1 OAP60495.1 - 2.4e-21 76.6 0.0 2.6e-20 73.2 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 OAP60495.1 - 5.2e-21 75.2 0.0 1.1e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 OAP60495.1 - 7.6e-18 64.4 0.0 2.5e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 OAP60495.1 - 1e-10 41.4 0.0 3.3e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 OAP60495.1 - 6.7e-05 22.8 0.0 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP60495.1 - 0.0036 16.9 0.0 0.0097 15.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 OAP60496.1 - 2e-84 283.6 0.0 7.4e-82 275.2 0.0 2.7 3 0 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 OAP60496.1 - 8.3e-40 134.9 0.0 1.8e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 OAP60496.1 - 9.4e-33 111.7 1.3 5.7e-32 109.2 0.3 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 OAP60496.1 - 2.9e-21 75.6 0.0 1.6e-20 73.2 0.0 2.3 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase NMO PF03060.10 OAP60496.1 - 7.2e-05 22.0 0.5 0.00095 18.4 0.4 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase Peptidase_C1 PF00112.18 OAP60498.1 - 0.00063 19.6 4.8 0.033 14.0 0.9 3.0 2 1 0 3 3 3 1 Papain family cysteine protease Peptidase_C39_2 PF13529.1 OAP60498.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase_C39 like family Transpep_BrtH PF14399.1 OAP60498.1 - 0.044 13.0 0.1 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase DUF1999 PF09390.5 OAP60498.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) Abhydrolase_6 PF12697.2 OAP60499.1 - 2.3e-26 93.1 0.1 2.8e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP60499.1 - 8.4e-11 41.8 0.1 5.2e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP60499.1 - 4.7e-07 29.6 0.0 6.3e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 OAP60499.1 - 0.0094 14.7 0.0 0.089 11.5 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) TPR_12 PF13424.1 OAP60500.1 - 1.2e-24 86.0 10.5 2.6e-08 33.6 0.6 5.9 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAP60500.1 - 1.9e-17 62.5 20.7 3.7e-06 26.6 0.7 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAP60500.1 - 2e-06 27.3 1.8 0.23 11.1 0.0 5.0 5 0 0 5 5 5 1 TPR repeat TPR_16 PF13432.1 OAP60500.1 - 3.7e-06 27.4 8.7 0.003 18.1 0.4 5.4 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP60500.1 - 4.4e-06 26.2 2.1 11 6.2 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 OAP60500.1 - 0.005 16.9 1.0 0.46 10.6 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 OAP60500.1 - 0.0087 16.1 0.1 6.9 7.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAP60500.1 - 0.012 15.1 2.0 3.6 7.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAP60500.1 - 0.073 13.5 14.8 26 5.6 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAP60500.1 - 0.2 11.7 7.1 0.51 10.4 0.6 4.1 2 2 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP60500.1 - 0.83 10.4 15.9 1.4e+02 3.5 0.1 6.8 5 2 3 8 8 8 0 Tetratricopeptide repeat DUF1841 PF08897.6 OAP60500.1 - 1.6 8.5 7.7 7.3 6.4 0.2 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1841) Fungal_trans_2 PF11951.3 OAP60503.1 - 1.6e-37 129.0 0.2 2e-37 128.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M1 PF01433.15 OAP60504.1 - 3.2e-115 385.3 0.0 4.8e-115 384.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 OAP60504.1 - 6.6e-45 153.7 0.0 9.6e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 OAP60504.1 - 9e-21 74.2 0.3 2e-20 73.1 0.2 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Transp_cyt_pur PF02133.10 OAP60505.1 - 3.4e-103 345.5 34.6 3.9e-103 345.3 24.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.7 OAP60506.1 - 2.2e-98 329.0 0.0 4.7e-98 328.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 OAP60506.1 - 8.8e-51 172.7 12.8 2.5e-49 167.9 2.5 3.0 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 OAP60506.1 - 4.3e-30 104.4 9.3 8.3e-28 97.0 0.0 3.8 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 OAP60506.1 - 0.0015 16.9 1.0 0.11 10.7 0.0 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 OAP60506.1 - 0.0021 17.4 1.6 0.037 13.3 0.1 2.6 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 OAP60506.1 - 0.05 13.4 5.2 3.1 7.6 0.0 3.9 4 2 0 4 4 4 0 Cell division protein FtsA Amidohydro_5 PF13594.1 OAP60507.1 - 4.9e-08 32.6 0.1 7.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 OAP60507.1 - 0.008 16.2 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase ATG22 PF11700.3 OAP60509.1 - 2.8e-111 372.3 17.5 3.2e-111 372.1 12.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SHOCT PF09851.4 OAP60509.1 - 0.0018 17.6 2.9 0.0033 16.8 2.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain TcpE PF12648.2 OAP60509.1 - 0.37 10.9 4.2 0.31 11.1 0.8 2.6 2 0 0 2 2 2 0 TcpE family Peptidase_S15 PF02129.13 OAP60510.1 - 5.4e-57 193.2 0.1 7.3e-57 192.8 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 OAP60510.1 - 3.1e-40 138.3 0.0 4.7e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 OAP60510.1 - 8.4e-15 55.2 0.3 1.7e-14 54.2 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP60510.1 - 8.2e-09 35.3 0.0 4e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP60510.1 - 8.3e-05 22.2 0.1 0.00027 20.5 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP60510.1 - 8.9e-05 21.8 0.2 0.00024 20.4 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 OAP60510.1 - 0.0035 15.8 0.0 0.0061 15.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF2048 PF09752.4 OAP60510.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DLH PF01738.13 OAP60510.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.6 OAP60510.1 - 0.19 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fungal_trans_2 PF11951.3 OAP60512.1 - 3e-15 55.7 2.3 1.5e-11 43.5 0.1 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 OAP60513.1 - 5.2e-18 65.1 0.0 6.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 OAP60513.1 - 4.1e-07 28.9 0.0 6e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 OAP60513.1 - 0.0054 15.8 0.2 0.056 12.4 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family AA_permease PF00324.16 OAP60514.1 - 1.5e-98 330.2 38.1 1.8e-98 329.9 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP60514.1 - 9.6e-27 93.5 42.5 1.2e-26 93.2 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease TPP_enzyme_N PF02776.13 OAP60515.1 - 2.2e-34 118.3 0.5 2.2e-34 118.3 0.3 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAP60515.1 - 3.4e-17 62.4 0.1 2.8e-16 59.4 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP60515.1 - 3.2e-16 59.3 0.0 6.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ChlI PF13541.1 OAP60515.1 - 0.072 12.6 0.0 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase HET PF06985.6 OAP60516.1 - 7.3e-17 61.8 0.0 1.4e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YkuD PF03734.9 OAP60516.1 - 0.15 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain DUF1446 PF07287.6 OAP60517.1 - 4e-124 413.7 0.0 4.7e-124 413.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) DUF1446 PF07287.6 OAP60518.1 - 1.1e-124 415.5 0.2 1.4e-124 415.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Sec63 PF02889.11 OAP60520.1 - 2e-138 460.8 0.0 8.8e-93 310.9 0.4 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 OAP60520.1 - 7e-54 181.8 0.5 4.3e-28 97.9 0.5 3.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 OAP60520.1 - 2.3e-16 60.1 0.0 3.7e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAP60520.1 - 2.1e-15 56.3 0.0 3.4e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_19 PF13245.1 OAP60520.1 - 1.4e-06 27.9 0.1 0.014 15.0 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 OAP60520.1 - 1.7e-06 28.1 0.1 0.17 12.0 0.0 3.4 2 2 0 2 2 2 2 AAA domain SNF2_N PF00176.18 OAP60520.1 - 9e-06 24.6 0.3 0.097 11.4 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain IstB_IS21 PF01695.12 OAP60520.1 - 0.0048 16.3 0.1 5.6 6.3 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_10 PF12846.2 OAP60520.1 - 0.056 12.8 0.0 9.2 5.6 0.0 3.2 3 1 1 4 4 4 0 AAA-like domain Synaptobrevin PF00957.16 OAP60521.1 - 5.1e-14 51.6 0.4 8.6e-14 50.9 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 OAP60521.1 - 2.8e-13 49.2 0.0 4.6e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 OAP60521.1 - 0.093 12.5 0.2 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Acetyltransf_1 PF00583.19 OAP60522.1 - 3.4e-19 68.6 0.0 5.3e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP60522.1 - 1.3e-09 38.0 0.0 2.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP60522.1 - 2.9e-09 37.0 0.0 4.8e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAP60522.1 - 4.8e-06 26.7 0.0 6.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP60522.1 - 5e-06 26.1 0.0 7.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAP60522.1 - 0.00011 22.0 0.1 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP60522.1 - 0.0014 18.6 0.0 0.0047 16.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP60522.1 - 0.004 17.0 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 OAP60522.1 - 0.0044 16.8 0.0 0.0095 15.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.3 OAP60523.1 - 0.0038 15.8 0.0 0.088 11.3 0.0 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain DUF2755 PF10954.3 OAP60524.1 - 0.0032 17.1 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2755) Spc97_Spc98 PF04130.8 OAP60524.1 - 0.048 11.9 0.3 0.064 11.5 0.2 1.2 1 0 0 1 1 1 0 Spc97 / Spc98 family adh_short PF00106.20 OAP60526.1 - 1.7e-19 70.3 0.1 2.4e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60526.1 - 3e-14 53.3 0.0 3.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 OAP60526.1 - 1.8e-06 27.3 0.0 2.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP60526.1 - 5.8e-06 26.4 0.1 9.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 OAP60526.1 - 0.00061 18.8 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 OAP60526.1 - 0.0012 18.5 0.1 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP60526.1 - 0.0051 16.2 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 OAP60526.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 OAP60526.1 - 0.092 12.5 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Brr6_like_C_C PF10104.4 OAP60527.1 - 1.3e-43 147.7 1.2 1.6e-43 147.4 0.8 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DNA_binding_1 PF01035.15 OAP60528.1 - 5.7e-20 70.8 0.0 9.9e-20 70.0 0.0 1.3 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Abhydrolase_6 PF12697.2 OAP60529.1 - 0.0008 19.3 0.0 0.00088 19.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Umbravirus_LDM PF04817.7 OAP60530.1 - 0.047 12.8 2.6 0.062 12.4 1.8 1.2 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Bud13 PF09736.4 OAP60531.1 - 4.3e-40 137.3 6.8 4.3e-40 137.3 4.7 3.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex HSP70 PF00012.15 OAP60532.1 - 0.007 14.3 0.0 0.0093 13.9 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAP60532.1 - 0.018 13.6 0.5 0.11 11.1 0.2 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Hydantoinase_A PF01968.13 OAP60532.1 - 0.13 11.3 0.2 0.39 9.7 0.1 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase SKG6 PF08693.5 OAP60533.1 - 0.0014 17.9 0.1 0.0034 16.6 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 OAP60533.1 - 0.02 14.3 0.2 0.044 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Rax2 PF12768.2 OAP60533.1 - 0.034 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF1517 PF07466.6 OAP60535.1 - 6.6e-05 22.0 0.9 9.1e-05 21.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) Herpes_gE PF02480.11 OAP60535.1 - 0.0001 20.6 0.2 0.00015 20.1 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 OAP60535.1 - 0.00023 20.7 1.6 0.0005 19.6 0.0 2.3 2 0 0 2 2 2 1 Syndecan domain DAG1 PF05454.6 OAP60535.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.1 OAP60535.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Rax2 PF12768.2 OAP60535.1 - 0.032 13.4 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Gly-zipper_Omp PF13488.1 OAP60535.1 - 0.1 12.2 9.4 0.24 11.0 6.5 1.6 1 0 0 1 1 1 0 Glycine zipper CoA_transf_3 PF02515.12 OAP60536.1 - 6.9e-53 178.7 0.1 9.5e-53 178.2 0.1 1.2 1 0 0 1 1 1 1 CoA-transferase family III Fungal_trans PF04082.13 OAP60537.1 - 5.7e-11 41.7 2.0 1e-10 40.9 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4211 PF13926.1 OAP60537.1 - 0.062 12.6 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) p450 PF00067.17 OAP60538.1 - 7e-63 212.7 0.0 9e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_4 PF13577.1 OAP60539.1 - 3.4e-13 49.6 3.4 4.1e-13 49.3 2.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 OAP60539.1 - 1.5e-05 25.3 0.8 2.3e-05 24.7 0.4 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 OAP60539.1 - 0.00011 22.3 1.5 0.00015 21.9 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) FAD_binding_3 PF01494.14 OAP60540.1 - 3.7e-43 147.9 0.0 5.1e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP60540.1 - 3e-05 23.1 0.0 0.00097 18.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP60540.1 - 0.00022 20.2 0.3 0.0035 16.2 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 OAP60540.1 - 0.00054 19.9 0.2 0.002 18.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP60540.1 - 0.0017 17.3 0.1 0.042 12.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 OAP60540.1 - 0.0027 16.2 0.3 0.018 13.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAP60540.1 - 0.0035 17.2 0.0 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP60540.1 - 0.0068 15.5 0.2 0.015 14.3 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP60540.1 - 0.0073 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family ThiF PF00899.16 OAP60540.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 OAP60540.1 - 0.045 12.6 0.0 0.2 10.5 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP60540.1 - 0.076 13.0 0.1 0.45 10.5 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.6 OAP60541.1 - 3.2e-23 82.4 0.0 8.3e-23 81.0 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF383 PF04063.9 OAP60544.1 - 1.9e-68 229.7 0.0 7.9e-68 227.7 0.0 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 OAP60544.1 - 5.4e-22 77.1 2.1 5.4e-22 77.1 1.5 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 OAP60544.1 - 0.028 14.6 0.5 4.8 7.5 0.1 3.3 2 1 0 2 2 2 0 HEAT repeats DUF3361 PF11841.3 OAP60544.1 - 0.19 11.4 0.4 0.37 10.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) PI3_PI4_kinase PF00454.22 OAP60545.1 - 1.7e-51 174.9 0.1 4.3e-51 173.6 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 OAP60545.1 - 6.8e-38 130.5 0.3 9.5e-37 126.7 0.3 2.6 2 0 0 2 2 2 1 FAT domain UME PF08064.8 OAP60545.1 - 1.7e-30 105.1 0.7 1.2e-29 102.4 0.0 3.0 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 OAP60545.1 - 3e-14 52.1 0.0 1.2e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 FATC domain TPR_19 PF14559.1 OAP60545.1 - 0.0016 18.7 0.7 0.032 14.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAP60545.1 - 0.041 13.5 0.2 3.8 7.2 0.0 3.8 4 1 0 4 4 4 0 TPR repeat TPR_14 PF13428.1 OAP60545.1 - 2.8 8.8 9.0 41 5.2 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Swi3 PF07962.7 OAP60546.1 - 1.9e-26 91.5 1.1 2.1e-26 91.3 0.0 1.6 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 NADH_u_ox_C PF12853.2 OAP60547.1 - 2.7e-32 110.3 0.1 4.9e-32 109.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 OAP60547.1 - 2e-26 92.0 0.5 3.7e-26 91.1 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Rop-like PF05082.8 OAP60547.1 - 0.013 14.9 0.0 0.062 12.7 0.0 2.2 1 0 0 1 1 1 0 Rop-like DUF1795 PF08786.6 OAP60548.1 - 0.041 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) Sec3_C_2 PF15278.1 OAP60549.1 - 0.16 12.1 1.1 25 5.0 0.0 3.3 3 0 0 3 3 3 0 Sec3 exocyst complex subunit PRKCSH-like PF12999.2 OAP60550.1 - 2.3e-47 160.8 2.8 5e-26 91.3 0.4 2.6 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 OAP60550.1 - 3.5e-33 114.2 0.6 1.7e-32 112.0 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 OAP60550.1 - 2.5e-11 44.2 0.2 6.2e-11 42.9 0.2 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF970 PF06153.6 OAP60550.1 - 0.055 13.4 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF970) DNA_pol3_beta_3 PF02768.10 OAP60550.1 - 0.084 12.4 3.7 0.17 11.4 2.6 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain MutS_IV PF05190.13 OAP60550.1 - 0.19 11.8 5.4 0.94 9.6 0.5 3.1 3 0 0 3 3 3 0 MutS family domain IV Fib_alpha PF08702.5 OAP60550.1 - 0.21 11.6 3.0 8.7 6.4 0.7 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 OAP60550.1 - 0.29 11.4 4.8 2 8.7 0.0 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Tropomyosin PF00261.15 OAP60550.1 - 1.3 8.0 21.6 0.15 11.1 5.5 3.0 3 0 0 3 3 3 0 Tropomyosin OEP PF02321.13 OAP60550.1 - 7.1 6.1 15.3 8.8 5.8 0.7 2.5 2 1 0 2 2 2 0 Outer membrane efflux protein F-box-like PF12937.2 OAP60551.1 - 0.013 15.1 2.5 0.033 13.9 0.1 2.7 3 0 0 3 3 3 0 F-box-like Kinetocho_Slk19 PF12709.2 OAP60552.1 - 5.8e-16 58.3 5.3 5.8e-16 58.3 3.7 4.1 3 2 1 4 4 4 2 Central kinetochore-associated IncA PF04156.9 OAP60552.1 - 4.1e-05 23.2 4.5 4.1e-05 23.2 3.1 2.6 2 1 0 2 2 2 1 IncA protein Myosin_tail_1 PF01576.14 OAP60552.1 - 0.0043 14.8 38.3 0.2 9.3 11.1 2.3 1 1 1 2 2 2 2 Myosin tail AHS1 PF02682.11 OAP60552.1 - 0.069 12.6 0.4 0.19 11.1 0.2 1.7 1 1 0 1 1 1 0 Allophanate hydrolase subunit 1 Filament PF00038.16 OAP60552.1 - 0.96 8.8 28.3 0.83 9.0 3.6 2.9 2 2 0 2 2 2 0 Intermediate filament protein HALZ PF02183.13 OAP60552.1 - 1.5 8.5 9.0 0.66 9.7 0.3 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3584 PF12128.3 OAP60552.1 - 1.7 5.8 27.3 0.046 11.0 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Nup54 PF13874.1 OAP60552.1 - 5.4 6.6 15.9 0.023 14.3 1.8 3.0 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Spc7 PF08317.6 OAP60552.1 - 9.2 4.8 26.0 1.7 7.1 6.3 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein Lyase_1 PF00206.15 OAP60554.1 - 2.6e-39 135.2 0.0 4.3e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 OAP60554.1 - 1.3e-22 79.6 0.0 2.5e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Crp PF00325.15 OAP60554.1 - 0.11 11.9 0.0 2.9 7.4 0.0 2.7 1 1 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF3505 PF12013.3 OAP60554.1 - 0.11 12.6 0.1 6.9 6.9 0.0 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3505) GST_C_3 PF14497.1 OAP60555.1 - 1.9e-11 44.3 0.0 3.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAP60555.1 - 1.9e-08 34.1 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAP60555.1 - 0.0036 17.4 0.0 0.017 15.2 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ADH_zinc_N PF00107.21 OAP60556.1 - 1.6e-09 37.4 0.0 2.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP60556.1 - 0.001 18.7 0.2 0.0029 17.3 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RST PF12174.3 OAP60556.1 - 0.0061 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain HC2 PF07382.6 OAP60557.1 - 2.6e-05 24.1 13.9 2.6e-05 24.1 9.6 1.6 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 DUF1680 PF07944.7 OAP60558.1 - 1e-104 350.7 0.0 1.2e-104 350.4 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) QRPTase_C PF01729.14 OAP60558.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain MFS_1 PF07690.11 OAP60559.1 - 4.3e-09 35.5 23.8 4.3e-09 35.5 16.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAP60559.1 - 5.5e-05 22.6 3.3 5.5e-05 22.6 2.3 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Bac_luciferase PF00296.15 OAP60560.1 - 3.8e-59 200.3 4.8 6.5e-59 199.5 3.3 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase NMO PF03060.10 OAP60560.1 - 0.017 14.2 0.2 0.92 8.5 0.0 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase HrpB4 PF09502.5 OAP60560.1 - 0.064 12.4 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) MFS_1 PF07690.11 OAP60561.1 - 1.8e-34 119.0 34.8 1.8e-34 119.0 24.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 OAP60561.1 - 3 8.2 4.5 45 4.5 0.1 3.3 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF202 PF02656.10 OAP60561.1 - 3.1 8.0 16.5 2.3 8.4 0.7 5.2 4 2 0 5 5 5 0 Domain of unknown function (DUF202) adh_short PF00106.20 OAP60562.1 - 3.5e-10 40.0 0.2 5.6e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60562.1 - 0.0025 17.6 0.1 0.0035 17.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP60562.1 - 0.003 17.2 0.1 0.0044 16.7 0.1 1.3 1 0 0 1 1 1 1 KR domain ApoLp-III PF07464.6 OAP60562.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Shikimate_DH PF01488.15 OAP60562.1 - 0.032 14.3 0.2 0.065 13.3 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 OAP60563.1 - 1.6e-12 47.2 0.3 2.9e-06 26.6 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 OAP60563.1 - 2.1e-06 26.8 0.1 3.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP60563.1 - 4.1e-06 26.7 0.1 1.2e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP60563.1 - 0.00034 20.5 0.1 0.00061 19.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP60563.1 - 0.00037 19.1 0.0 0.0013 17.2 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 OAP60563.1 - 0.00049 19.0 0.1 0.0008 18.3 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 OAP60563.1 - 0.0005 19.2 0.1 0.0021 17.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 OAP60563.1 - 0.001 18.0 0.8 0.0035 16.3 0.3 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP60563.1 - 0.0014 19.0 0.2 0.046 14.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP60563.1 - 0.03 13.3 0.1 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 OAP60563.1 - 0.062 12.2 0.0 7.4 5.3 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 OAP60563.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XPG_I_2 PF12813.2 OAP60564.1 - 1.8e-47 161.9 0.0 2.7e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 OAP60564.1 - 0.0024 17.9 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region NAD_binding_4 PF07993.7 OAP60565.1 - 2.3e-42 144.6 0.0 4.3e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 OAP60565.1 - 1.1e-36 126.1 0.0 5e-36 123.9 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 OAP60565.1 - 1.8e-10 40.6 0.0 4.8e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 OAP60565.1 - 6.5e-10 39.1 0.0 2e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AAA_33 PF13671.1 OAP60565.1 - 3.4e-08 33.4 0.3 6.9e-07 29.2 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 OAP60565.1 - 7.9e-06 26.2 0.7 0.00018 21.8 0.5 3.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP60565.1 - 1.5e-05 25.7 0.0 6.6e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 OAP60565.1 - 1.9e-05 24.5 1.5 0.00012 21.9 0.1 2.8 2 1 0 2 2 2 1 Shikimate kinase adh_short PF00106.20 OAP60565.1 - 3.6e-05 23.7 0.7 0.00034 20.5 0.5 2.6 1 1 0 1 1 1 1 short chain dehydrogenase AAA_16 PF13191.1 OAP60565.1 - 6.9e-05 22.9 0.1 0.00023 21.2 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain 3Beta_HSD PF01073.14 OAP60565.1 - 8.3e-05 21.4 0.1 0.0012 17.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAP60565.1 - 0.00028 20.6 1.1 0.001 18.7 0.1 2.6 3 1 0 3 3 3 1 KR domain NACHT PF05729.7 OAP60565.1 - 0.00086 19.0 0.1 0.39 10.3 0.0 3.6 3 0 0 3 3 3 1 NACHT domain NAD_binding_10 PF13460.1 OAP60565.1 - 0.0034 17.4 0.6 0.013 15.5 0.1 2.2 3 0 0 3 3 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAP60565.1 - 0.024 13.5 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AAA_22 PF13401.1 OAP60565.1 - 0.024 14.7 0.0 0.25 11.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 OAP60565.1 - 0.027 14.6 0.0 0.12 12.5 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NmrA PF05368.8 OAP60565.1 - 0.041 13.1 0.1 0.083 12.1 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family DUF258 PF03193.11 OAP60565.1 - 0.042 13.0 0.0 0.098 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Semialdhyde_dh PF01118.19 OAP60565.1 - 0.064 13.5 0.0 0.24 11.6 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RNA_helicase PF00910.17 OAP60565.1 - 0.14 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CbiA PF01656.18 OAP60565.1 - 0.15 11.4 0.1 3.1 7.1 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fungal_trans PF04082.13 OAP60567.1 - 1.5e-26 92.8 0.5 2.3e-26 92.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60567.1 - 2.4e-06 27.3 5.8 4.6e-06 26.4 4.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 OAP60568.1 - 3.7e-57 193.3 0.0 4.5e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HlyIII PF03006.15 OAP60569.1 - 4.4e-52 176.6 18.2 5.3e-52 176.4 12.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related SnAC PF14619.1 OAP60569.1 - 0.0049 17.0 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex MaoC_dehydratas PF01575.14 OAP60570.1 - 3.1e-11 42.7 0.1 5.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain RibD_C PF01872.12 OAP60571.1 - 3e-28 98.8 0.0 6.3e-28 97.7 0.0 1.6 1 1 0 1 1 1 1 RibD C-terminal domain CDC45 PF02724.9 OAP60571.1 - 1.1 7.1 2.1 1.5 6.7 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 OAP60572.1 - 6.4e-14 51.3 0.0 9.2e-14 50.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP60572.1 - 2.2e-12 46.7 0.0 3.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP60572.1 - 0.0002 21.1 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cellulase-like PF12876.2 OAP60573.1 - 0.058 13.8 0.1 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like Kinesin PF00225.18 OAP60574.1 - 3.1e-28 98.4 0.1 7.6e-21 74.1 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Nop53 PF07767.6 OAP60574.1 - 0.027 13.4 0.4 0.037 13.0 0.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) AMP-binding PF00501.23 OAP60575.1 - 6.3e-85 285.0 0.0 9.5e-85 284.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP60575.1 - 4.6e-10 40.3 0.3 1.3e-09 38.8 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 OAP60575.1 - 2.8e-06 27.1 4.7 5.1e-06 26.2 3.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 OAP60575.1 - 1.9 8.1 5.6 4.5 6.9 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DSBA PF01323.15 OAP60576.1 - 8.7e-19 67.8 0.0 9.7e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Oxidored_molyb PF00174.14 OAP60577.1 - 3.3e-42 143.7 0.0 4.8e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 OAP60577.1 - 2.2e-12 46.7 0.0 3.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Gmad2 PF10648.4 OAP60577.1 - 0.00032 20.8 0.0 0.00065 19.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin-like domain of bacterial spore germination Big_3_4 PF13754.1 OAP60577.1 - 0.001 19.3 0.0 0.016 15.5 0.0 2.7 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 3) Y_Y_Y PF07495.8 OAP60577.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain Fungal_trans PF04082.13 OAP60578.1 - 5.6e-13 48.3 0.2 1e-12 47.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60578.1 - 3.2e-06 26.9 11.0 5.5e-06 26.1 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP_mutase PF13714.1 OAP60579.1 - 7.8e-53 179.1 0.4 9.1e-53 178.9 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 OAP60579.1 - 5.2e-22 77.7 0.4 6.9e-22 77.3 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 OAP60579.1 - 0.002 17.3 0.1 0.019 14.0 0.1 2.3 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase AMP-binding PF00501.23 OAP60580.1 - 1.4e-79 267.4 0.1 1.8e-79 267.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP60580.1 - 9e-17 61.7 0.3 1e-15 58.3 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PIP5K PF01504.13 OAP60581.1 - 1.7e-33 115.7 0.0 2.2e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Oxysterol_BP PF01237.13 OAP60582.1 - 3e-63 213.4 0.0 9.2e-63 211.8 0.0 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein TMEM171 PF15471.1 OAP60582.1 - 0.076 11.7 1.4 0.15 10.8 0.9 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Zn_clus PF00172.13 OAP60583.1 - 1.5e-08 34.3 11.4 2.8e-08 33.5 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP60583.1 - 0.00026 19.9 0.3 0.00049 19.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1712 PF08217.6 OAP60584.1 - 1.5e-14 53.1 0.0 6e-12 44.6 0.0 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Ras PF00071.17 OAP60585.1 - 3.5e-57 192.3 0.0 4.1e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP60585.1 - 2.6e-16 60.1 0.0 4.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP60585.1 - 2e-06 27.1 0.0 3.1e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAP60585.1 - 0.00061 19.2 0.0 0.0028 17.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAP60585.1 - 0.0064 15.7 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 OAP60585.1 - 0.022 13.8 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Abhydrolase_6 PF12697.2 OAP60586.1 - 6.6e-24 85.0 0.0 7.9e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP60586.1 - 1e-10 41.5 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family His_Phos_1 PF00300.17 OAP60586.1 - 0.026 14.6 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) DLH PF01738.13 OAP60586.1 - 0.079 12.2 0.0 8.2 5.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family E1-E2_ATPase PF00122.15 OAP60587.1 - 1.3e-52 178.1 0.4 2.7e-52 177.0 0.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAP60587.1 - 2.2e-36 125.0 5.7 2.2e-36 125.0 3.9 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAP60587.1 - 6e-28 98.7 0.0 3.8e-27 96.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAP60587.1 - 3.5e-16 59.9 0.0 9.6e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP60587.1 - 3.7e-13 49.2 0.0 7.6e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAP60587.1 - 9.4e-11 41.0 0.0 2.2e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2231 PF09990.4 OAP60587.1 - 0.0062 16.8 0.6 0.0062 16.8 0.5 2.7 3 0 0 3 3 3 1 Predicted membrane protein (DUF2231) HET PF06985.6 OAP60588.1 - 1e-25 90.5 0.1 1.6e-25 89.9 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) C1_3 PF07649.7 OAP60588.1 - 0.00076 19.4 9.4 0.0018 18.2 6.5 1.7 1 0 0 1 1 1 1 C1-like domain ZZ PF00569.12 OAP60588.1 - 0.0071 15.8 9.0 0.015 14.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.15 OAP60588.1 - 0.47 10.2 10.3 0.028 14.1 3.3 1.9 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) C1_2 PF03107.11 OAP60588.1 - 1.2 9.2 10.1 3.3 7.8 7.0 1.8 1 0 0 1 1 1 0 C1 domain MARVEL PF01284.18 OAP60589.1 - 1.6 8.5 7.6 0.29 10.9 1.9 2.1 2 1 0 2 2 2 0 Membrane-associating domain PhoD PF09423.5 OAP60590.1 - 5.9e-09 35.0 0.0 5.7e-07 28.4 0.1 2.4 2 1 0 2 2 2 2 PhoD-like phosphatase Rad51 PF08423.6 OAP60591.1 - 5.3e-138 458.0 0.0 6.5e-138 457.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 OAP60591.1 - 8.6e-14 51.3 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 OAP60591.1 - 1.5e-09 37.3 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 OAP60591.1 - 3e-07 30.4 0.0 9.3e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 OAP60591.1 - 2.6e-06 26.7 0.0 4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.6 OAP60591.1 - 0.028 13.2 0.2 0.13 11.1 0.1 1.8 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.10 OAP60591.1 - 0.064 12.1 0.1 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Erythro_esteras PF05139.9 OAP60591.1 - 0.13 11.4 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Erythromycin esterase Transferase PF02458.10 OAP60592.1 - 1.9e-23 82.6 0.0 6.7e-17 61.0 0.0 2.8 2 1 0 2 2 2 2 Transferase family PXA PF02194.10 OAP60593.1 - 7.5e-51 172.3 0.3 7.5e-51 172.3 0.2 2.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 OAP60593.1 - 3.9e-24 84.9 2.5 1e-23 83.5 0.1 2.8 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 OAP60593.1 - 9.2e-22 76.9 1.3 2.6e-21 75.5 0.5 2.2 2 0 0 2 2 2 1 PX domain RGS PF00615.14 OAP60593.1 - 5.6e-12 45.7 0.1 2.1e-11 43.9 0.1 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain CPDase PF07823.6 OAP60593.1 - 0.1 12.0 0.0 13 5.1 0.0 2.7 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein Pyr_redox_3 PF13738.1 OAP60594.1 - 1.1e-19 71.3 0.0 4.8e-19 69.2 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP60594.1 - 5.7e-10 39.0 0.0 1.7e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 OAP60594.1 - 1e-09 37.2 0.0 2.1e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP60594.1 - 1.1e-05 24.4 0.1 0.0042 16.0 0.0 3.6 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP60594.1 - 0.027 14.2 0.1 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Cupin_8 PF13621.1 OAP60595.1 - 4.8e-25 88.4 0.0 5.5e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain DUF3701 PF12482.3 OAP60595.1 - 0.0045 16.7 0.7 0.0081 15.8 0.5 1.4 1 0 0 1 1 1 1 Phage integrase protein Cupin_4 PF08007.7 OAP60595.1 - 0.0058 15.9 0.0 0.013 14.7 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 OAP60595.1 - 0.016 15.4 0.0 0.12 12.6 0.0 2.3 3 0 0 3 3 3 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 OAP60595.1 - 0.05 13.1 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Cupin domain CK_II_beta PF01214.13 OAP60596.1 - 1e-74 250.0 0.0 3.3e-74 248.3 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Myc_N PF01056.13 OAP60596.1 - 2.2 7.3 7.3 7.9 5.5 0.6 2.3 2 0 0 2 2 2 0 Myc amino-terminal region DUF2890 PF11081.3 OAP60596.1 - 2.4 8.1 11.5 4.1 7.4 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Spt5_N PF11942.3 OAP60596.1 - 9 6.9 20.0 7.2 7.3 2.3 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Fungal_trans PF04082.13 OAP60597.1 - 3.6e-18 65.3 0.0 5.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60597.1 - 2e-05 24.3 6.5 3.8e-05 23.5 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.5 OAP60597.1 - 0.069 13.1 0.2 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 HalX domain CIA30 PF08547.7 OAP60598.1 - 1.5e-24 86.6 0.0 2.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.16 OAP60598.1 - 2.3e-05 24.2 4.7 3.8e-05 23.5 3.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP60598.1 - 0.0024 17.6 6.7 0.0039 16.9 4.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 OAP60598.1 - 0.27 11.5 6.6 0.49 10.7 4.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Col_cuticle_N PF01484.12 OAP60600.1 - 5.7 6.7 9.1 10 5.9 6.3 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DEAD PF00270.24 OAP60601.1 - 6.2e-47 159.2 0.0 3e-46 157.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP60601.1 - 1.5e-24 85.5 0.2 9.1e-24 83.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAP60601.1 - 0.0023 16.8 0.0 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 OAP60601.1 - 0.017 14.9 0.0 0.11 12.2 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit HMG_box PF00505.14 OAP60602.1 - 1.2e-13 51.0 11.6 3.1e-10 40.1 0.9 3.2 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAP60602.1 - 1.4e-13 51.0 13.5 2.5e-11 43.7 0.3 3.4 2 1 1 3 3 3 2 HMG-box domain Ribosomal_L10 PF00466.15 OAP60603.1 - 0.013 15.3 0.0 0.073 12.9 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L10 SCP1201-deam PF14428.1 OAP60603.1 - 0.046 13.4 0.0 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 SCP1.201-like deaminase Toxin_39 PF15500.1 OAP60603.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNase-like toxin SSF PF00474.12 OAP60604.1 - 1.4e-17 63.4 31.9 2.2e-17 62.8 22.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family p450 PF00067.17 OAP60605.1 - 1.6e-72 244.4 0.0 2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 OAP60606.1 - 2.1e-14 53.7 0.0 4.8e-14 52.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP60606.1 - 6.8e-12 45.9 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP60606.1 - 2e-11 44.1 0.0 3.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP60606.1 - 8.6e-10 38.5 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP60606.1 - 2.7e-09 36.7 0.0 3.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP60606.1 - 1.6e-07 31.3 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP60606.1 - 4.2e-07 29.5 0.0 7.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 OAP60606.1 - 6.7e-07 29.7 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 OAP60606.1 - 2.2e-05 23.3 0.0 2.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Ubie_methyltran PF01209.13 OAP60606.1 - 0.00013 21.1 0.0 0.0019 17.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 OAP60606.1 - 0.00055 19.0 0.0 0.00071 18.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 OAP60606.1 - 0.00068 19.0 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.9 OAP60606.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.5 OAP60606.1 - 0.0092 15.5 0.1 0.02 14.4 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 OAP60606.1 - 0.016 14.3 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.13 OAP60606.1 - 0.062 12.5 0.0 2.4 7.4 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.4 OAP60606.1 - 0.075 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UPF0146 PF03686.8 OAP60606.1 - 0.13 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) MFS_1 PF07690.11 OAP60607.1 - 2e-20 72.7 43.1 7.6e-19 67.6 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP60607.1 - 0.00024 19.8 8.9 0.00024 19.8 6.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter 2OG-FeII_Oxy_3 PF13640.1 OAP60608.1 - 5.6e-06 26.7 0.0 9.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAP60608.1 - 0.0001 22.4 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 OAP60609.1 - 1.6e-18 67.1 0.1 4.2e-18 65.8 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60609.1 - 3e-08 33.7 0.0 1.3e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP60609.1 - 2.4e-07 30.6 0.1 0.00063 19.4 0.0 2.2 2 0 0 2 2 2 2 KR domain Glyco_hydr_30_2 PF14587.1 OAP60609.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Mito_carr PF00153.22 OAP60609.1 - 0.39 10.4 2.3 1.8 8.3 0.0 2.9 4 0 0 4 4 4 0 Mitochondrial carrier protein adh_short PF00106.20 OAP60610.1 - 1.5e-25 90.0 0.0 2.9e-25 89.1 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP60610.1 - 2e-16 60.4 0.1 2.8e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP60610.1 - 2.9e-08 33.5 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP60610.1 - 1.1e-05 24.9 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP60610.1 - 0.013 15.2 2.1 0.53 10.0 0.6 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 OAP60610.1 - 0.098 12.3 0.1 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.23 OAP60611.1 - 4.4e-64 216.4 0.0 5.2e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP60611.1 - 1.1e-15 58.2 0.0 2.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_4 PF12799.2 OAP60612.1 - 3.9e-13 48.6 9.7 0.24 11.0 0.0 8.0 7 1 1 8 8 8 5 Leucine Rich repeats (2 copies) F-box-like PF12937.2 OAP60612.1 - 2.1e-10 40.1 0.7 8e-10 38.2 0.5 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 OAP60612.1 - 3.8e-09 36.1 15.1 0.067 12.9 0.4 6.9 3 2 3 7 7 7 7 Leucine rich repeat F-box PF00646.28 OAP60612.1 - 5.5e-05 22.7 0.2 0.00024 20.6 0.1 2.3 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.6 OAP60612.1 - 0.51 9.8 1.7 1.2 8.7 0.1 2.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1699) NigD PF12667.2 OAP60613.1 - 0.063 13.0 0.2 0.095 12.4 0.1 1.2 1 0 0 1 1 1 0 NigD-like protein Glyco_hydro_15 PF00723.16 OAP60614.1 - 0.027 13.0 0.4 0.042 12.3 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Mpv17_PMP22 PF04117.7 OAP60614.1 - 0.028 14.0 0.3 0.07 12.7 0.2 1.6 1 0 0 1 1 1 0 Mpv17 / PMP22 family TPR_12 PF13424.1 OAP60614.1 - 0.03 14.2 0.0 2.2 8.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.9 OAP60614.1 - 0.098 12.1 0.2 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain MFS_1 PF07690.11 OAP60615.1 - 9.8e-20 70.5 67.0 5e-19 68.2 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM237 PF15383.1 OAP60616.1 - 0.011 14.8 1.4 0.017 14.2 1.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Ribosomal_L1 PF00687.16 OAP60618.1 - 2e-52 177.7 0.7 2.4e-52 177.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Acetyltransf_1 PF00583.19 OAP60619.1 - 2.2e-14 53.2 0.0 4.6e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 OAP60619.1 - 4.9e-10 39.0 0.0 1.2e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAP60619.1 - 3.9e-09 36.5 0.0 6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP60619.1 - 2.9e-06 27.4 0.0 4.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP60619.1 - 4.1e-06 26.5 0.0 7.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 OAP60619.1 - 3.1e-05 23.9 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAP60619.1 - 6.3e-05 23.1 0.0 8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP60619.1 - 0.02 14.7 0.0 0.052 13.4 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 OAP60620.1 - 6.2e-80 266.5 0.1 7.3e-80 266.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 OAP60620.1 - 4e-14 52.2 0.0 4.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 OAP60620.1 - 5.8e-13 48.5 0.0 6.3e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 OAP60620.1 - 2e-12 46.5 1.6 2.2e-09 36.5 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 OAP60620.1 - 4.6e-11 42.3 0.0 5.3e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 OAP60620.1 - 1.9e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAP60620.1 - 2.8e-06 27.2 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 OAP60620.1 - 0.0094 15.0 0.4 0.017 14.2 0.3 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 OAP60620.1 - 0.013 14.9 0.1 0.11 11.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 OAP60620.1 - 0.044 13.6 0.2 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain Aconitase PF00330.15 OAP60621.1 - 7.6e-65 219.1 0.0 2.2e-31 108.8 0.0 3.1 1 1 2 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAP60621.1 - 5.7e-20 71.7 0.0 1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2686 PF10887.3 OAP60621.1 - 0.00059 18.6 0.1 0.001 17.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2686) WH2 PF02205.15 OAP60622.1 - 2.9e-10 39.4 3.2 5.1e-10 38.6 0.4 2.3 2 0 0 2 2 2 1 WH2 motif Ribosomal_60s PF00428.14 OAP60623.1 - 0.15 12.4 20.2 0.79 10.1 4.1 2.4 1 1 1 2 2 2 0 60s Acidic ribosomal protein DUF3431 PF11913.3 OAP60624.1 - 5.8e-15 55.3 0.0 2.1e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) CHORD PF04968.7 OAP60625.1 - 8.6e-34 115.5 11.8 5.6e-24 84.1 5.3 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.11 OAP60625.1 - 2.9e-13 50.1 0.0 6.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 CS domain SIR2 PF02146.12 OAP60628.1 - 4.2e-28 98.2 0.0 2.3e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.3 OAP60629.1 - 2.2e-57 194.6 0.0 2.6e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 Ribosomal_L29 PF00831.18 OAP60630.1 - 2.3e-19 68.7 0.1 2.3e-19 68.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal L29 protein DUF3585 PF12130.3 OAP60630.1 - 0.2 11.5 2.0 0.26 11.1 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) Cortex-I_coil PF09304.5 OAP60630.1 - 1.5 8.9 5.3 0.45 10.5 1.2 1.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil V-SNARE_C PF12352.3 OAP60631.1 - 1e-15 57.5 0.6 1e-15 57.5 0.4 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.1 OAP60631.1 - 0.00061 18.4 7.5 0.00079 18.0 5.2 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 AAA_13 PF13166.1 OAP60631.1 - 0.0093 14.4 1.7 0.011 14.2 1.2 1.1 1 0 0 1 1 1 1 AAA domain P16-Arc PF04699.9 OAP60631.1 - 0.021 14.8 1.0 0.038 14.0 0.3 1.7 1 1 1 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Surfac_D-trimer PF09006.6 OAP60631.1 - 0.041 13.5 0.6 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation MtrG PF04210.8 OAP60631.1 - 0.14 11.8 0.3 0.32 10.6 0.2 1.8 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Syntaxin-6_N PF09177.6 OAP60631.1 - 0.18 12.1 5.8 0.46 10.9 1.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 OAP60631.1 - 0.32 10.5 14.2 0.27 10.8 8.9 1.6 1 1 0 1 1 1 0 IncA protein Syntaxin_2 PF14523.1 OAP60631.1 - 0.62 10.1 6.9 16 5.5 0.1 3.0 1 1 1 2 2 2 0 Syntaxin-like protein Pox_A_type_inc PF04508.7 OAP60631.1 - 0.77 9.7 8.9 6.2 6.8 0.3 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FliD_N PF02465.13 OAP60631.1 - 1.1 9.6 3.4 6.6 7.1 0.3 2.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Syntaxin PF00804.20 OAP60631.1 - 2.3 8.4 6.5 2.9 8.1 3.1 2.1 1 1 1 2 2 2 0 Syntaxin ATP-synt_10 PF05176.9 OAP60632.1 - 9e-73 244.6 0.0 1.2e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.1 OAP60633.1 - 2.1e-27 95.3 0.0 9.4e-27 93.2 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 OAP60633.1 - 5.4e-20 70.6 0.6 1.1e-19 69.6 0.4 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 OAP60633.1 - 1.3e-10 41.2 0.1 2.8e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Zn_clus PF00172.13 OAP60633.1 - 0.0014 18.4 4.6 0.0034 17.2 3.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTP_transf_2 PF01909.18 OAP60633.1 - 0.0026 18.0 0.0 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PsbU PF06514.6 OAP60633.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) BRCT PF00533.21 OAP60633.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain zf-BED PF02892.10 OAP60633.1 - 0.017 14.8 0.1 0.05 13.3 0.1 1.8 1 0 0 1 1 1 0 BED zinc finger PTCB-BRCT PF12738.2 OAP60633.1 - 0.098 12.5 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain 5_3_exonuc PF01367.15 OAP60633.1 - 0.14 12.4 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF2619 PF10942.3 OAP60633.1 - 0.26 11.2 0.0 0.5 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2619) CRC_subunit PF08624.5 OAP60634.1 - 7.4e-55 184.6 0.1 1e-54 184.2 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit FAD_binding_3 PF01494.14 OAP60635.1 - 2.6e-22 79.3 0.3 7.3e-22 77.8 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP60635.1 - 1.3e-11 44.0 4.7 4.6e-05 22.4 1.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP60635.1 - 6.1e-07 29.7 1.0 8.8e-05 22.8 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP60635.1 - 2.1e-06 27.6 0.6 4.6e-06 26.5 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP60635.1 - 4.9e-06 25.2 2.3 0.0024 16.3 0.9 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 OAP60635.1 - 6.1e-06 25.3 5.2 1.6e-05 23.9 1.7 2.3 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.12 OAP60635.1 - 9.5e-06 24.8 0.4 0.011 14.7 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 OAP60635.1 - 1.6e-05 24.8 0.9 2.9e-05 24.0 0.3 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP60635.1 - 4.3e-05 22.5 1.1 5.9e-05 22.0 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAP60635.1 - 5.2e-05 22.3 1.6 0.00061 18.8 1.1 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 OAP60635.1 - 0.00087 18.4 1.0 0.0015 17.7 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAP60635.1 - 0.0011 17.6 3.2 0.0054 15.4 0.7 2.5 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 OAP60635.1 - 0.0013 18.7 0.1 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP60635.1 - 0.0025 16.9 0.2 0.7 8.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAP60635.1 - 0.0044 16.7 0.3 0.015 15.0 0.1 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 OAP60635.1 - 0.047 13.2 1.9 0.049 13.1 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 OAP60635.1 - 0.15 11.7 0.3 0.4 10.3 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 OAP60636.1 - 1e-29 103.4 26.1 1e-29 103.4 18.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP60636.1 - 5.4e-05 21.5 1.1 8.8e-05 20.8 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 OAP60637.1 - 3.5e-08 32.6 0.4 1.6e-07 30.5 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain SLD3 PF08639.5 OAP60638.1 - 3.9e-90 302.8 8.1 7.3e-90 301.9 5.5 1.5 1 1 1 2 2 2 1 DNA replication regulator SLD3 IncA PF04156.9 OAP60638.1 - 2.2 7.8 5.2 1.4 8.4 1.0 2.1 2 0 0 2 2 2 0 IncA protein SNARE PF05739.14 OAP60639.1 - 1.1e-19 69.8 1.7 3.3e-19 68.3 1.2 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.1 OAP60639.1 - 1.5e-18 66.7 2.0 1.5e-18 66.7 1.4 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.20 OAP60639.1 - 0.032 14.3 4.1 0.04 14.0 0.4 2.3 2 0 0 2 2 2 0 Syntaxin PMC2NT PF08066.7 OAP60639.1 - 0.051 13.8 0.3 0.58 10.4 0.0 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Nitr_red_assoc PF09655.5 OAP60639.1 - 0.051 13.8 0.1 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF883 PF05957.8 OAP60639.1 - 0.093 13.1 4.3 0.31 11.4 0.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1352 PF07086.7 OAP60639.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) T2SF PF00482.18 OAP60639.1 - 0.71 9.7 3.3 2.3 8.1 0.3 2.7 2 2 1 3 3 3 0 Type II secretion system (T2SS), protein F Ndc1_Nup PF09531.5 OAP60640.1 - 2.8e-100 336.5 0.1 3.2e-100 336.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup IKI3 PF04762.7 OAP60641.1 - 3.3e-292 971.7 0.0 4e-292 971.4 0.0 1.1 1 0 0 1 1 1 1 IKI3 family DUF2298 PF10060.4 OAP60641.1 - 0.19 10.5 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) TPR_7 PF13176.1 OAP60641.1 - 3.3 7.7 8.2 1.1 9.2 0.3 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat COX7C PF02935.11 OAP60642.1 - 2e-15 56.3 1.2 2.2e-15 56.1 0.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 OAP60643.1 - 9.3e-97 323.3 0.4 9.3e-97 323.3 0.2 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 OAP60643.1 - 2.8e-56 189.6 1.2 2.8e-56 189.6 0.8 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain Cut8_C PF08559.5 OAP60643.1 - 3.7e-47 159.7 0.0 8.1e-47 158.6 0.0 1.6 1 0 0 1 1 1 1 Cut8 six-helix bundle DEAD PF00270.24 OAP60643.1 - 1.9e-21 76.2 0.0 5.1e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP60643.1 - 1.4e-07 31.2 0.0 3.7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP60643.1 - 0.0044 16.8 0.0 0.037 13.8 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 OAP60643.1 - 0.028 13.3 0.0 0.069 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein HAMP PF00672.20 OAP60643.1 - 0.21 11.7 0.2 26 5.0 0.0 2.6 2 0 0 2 2 2 0 HAMP domain Cyto_heme_lyase PF01265.12 OAP60644.1 - 8.6e-74 248.3 0.9 1.1e-73 248.1 0.7 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 OAP60645.1 - 4.6e-10 39.4 0.6 1.1e-09 38.1 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAP60645.1 - 0.0032 17.6 0.0 0.014 15.5 0.0 2.1 3 0 0 3 3 3 1 GHMP kinases C terminal FANCI_S3 PF14677.1 OAP60645.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 Pyr_redox_3 PF13738.1 OAP60646.1 - 1.2e-23 84.2 0.0 1.9e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP60646.1 - 2.3e-14 52.5 0.1 1.6e-13 49.7 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP60646.1 - 1.4e-10 41.0 0.0 7.6e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP60646.1 - 9.2e-09 34.6 0.1 2.5e-07 29.9 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAP60646.1 - 2.3e-06 26.7 0.0 2e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP60646.1 - 2.3e-05 23.6 0.0 0.00025 20.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.10 OAP60646.1 - 0.00029 19.1 0.1 0.063 11.4 0.0 2.7 2 1 1 3 3 3 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 OAP60646.1 - 0.00071 19.5 0.1 0.036 13.9 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP60646.1 - 0.0033 17.8 0.1 0.39 11.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP60646.1 - 0.0058 15.5 0.0 0.041 12.7 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.15 OAP60646.1 - 0.0097 16.0 0.0 0.41 10.7 0.0 3.0 4 0 0 4 4 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 OAP60646.1 - 0.026 14.2 1.3 10 5.8 0.1 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAP60646.1 - 0.046 12.5 0.3 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 OAP60646.1 - 0.059 13.6 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding zf-met2 PF12907.2 OAP60647.1 - 1.1e-11 44.4 2.4 1.8e-11 43.8 1.6 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 OAP60647.1 - 7.5e-08 32.9 9.7 7.5e-08 32.9 6.7 1.9 2 0 0 2 2 2 1 4F5 protein family Sigma70_ner PF04546.8 OAP60647.1 - 0.21 11.1 1.6 0.23 11.0 1.1 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Aminotran_3 PF00202.16 OAP60648.1 - 2.3e-78 263.4 0.0 3.3e-78 262.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 OAP60648.1 - 0.013 14.4 0.0 0.029 13.3 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II Halo_GVPC PF05465.8 OAP60649.1 - 0.092 12.6 0.6 0.18 11.7 0.4 1.4 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat AAA PF00004.24 OAP60651.1 - 2.9e-85 283.1 0.0 1.1e-41 142.1 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAP60651.1 - 7.3e-13 48.1 0.0 6.8e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAP60651.1 - 1.9e-12 47.5 3.3 2.3e-06 27.7 0.0 4.2 3 1 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 OAP60651.1 - 3.9e-11 43.8 0.1 3.1e-07 31.2 0.0 3.1 2 1 1 3 3 2 2 AAA domain AAA_22 PF13401.1 OAP60651.1 - 2.8e-10 40.4 2.1 0.00095 19.3 0.1 4.4 3 2 1 4 4 3 2 AAA domain AAA_14 PF13173.1 OAP60651.1 - 2.9e-10 40.1 0.0 4.1e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 OAP60651.1 - 3.9e-10 39.9 0.0 0.00014 21.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 OAP60651.1 - 1.4e-09 38.0 0.0 0.00012 21.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 OAP60651.1 - 2.1e-09 37.2 0.3 0.001 18.8 0.0 3.9 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 OAP60651.1 - 1.3e-08 34.1 1.7 0.00084 18.4 0.0 3.6 4 0 0 4 4 4 2 Zeta toxin AAA_28 PF13521.1 OAP60651.1 - 3.1e-08 33.7 0.0 8e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 OAP60651.1 - 3.1e-08 33.2 0.5 0.0064 16.2 0.0 3.7 4 0 0 4 4 3 2 Part of AAA domain RNA_helicase PF00910.17 OAP60651.1 - 4.8e-08 33.1 0.0 0.0011 19.1 0.0 3.1 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 OAP60651.1 - 2.6e-07 30.2 0.3 0.0037 16.7 0.0 2.5 2 1 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 OAP60651.1 - 3.4e-07 29.6 0.7 0.0045 16.1 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 OAP60651.1 - 3.8e-07 30.4 0.2 0.00053 20.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 OAP60651.1 - 9.3e-07 27.8 0.0 0.00018 20.3 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 OAP60651.1 - 2.3e-06 27.1 6.0 0.43 9.9 0.0 4.1 2 2 2 4 4 4 3 AAA domain ABC_tran PF00005.22 OAP60651.1 - 4.3e-06 27.0 0.8 0.4 10.9 0.0 4.2 4 0 0 4 4 4 2 ABC transporter AAA_3 PF07726.6 OAP60651.1 - 7.3e-06 25.6 0.0 0.0049 16.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 OAP60651.1 - 8.1e-06 25.5 3.3 0.095 12.3 0.0 5.2 5 2 2 7 7 6 1 NACHT domain Cytidylate_kin2 PF13189.1 OAP60651.1 - 2.7e-05 24.1 0.0 0.00062 19.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 OAP60651.1 - 3e-05 23.9 1.5 0.086 12.7 0.0 3.3 3 0 0 3 3 3 2 Shikimate kinase KaiC PF06745.8 OAP60651.1 - 4.5e-05 22.6 0.2 0.22 10.6 0.0 3.4 2 1 1 3 3 3 1 KaiC Sigma54_activ_2 PF14532.1 OAP60651.1 - 0.0002 21.4 0.4 0.063 13.3 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 OAP60651.1 - 0.00021 20.8 0.0 0.33 10.4 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 OAP60651.1 - 0.00041 19.1 0.0 0.025 13.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 OAP60651.1 - 0.00041 19.3 0.1 0.24 10.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 OAP60651.1 - 0.00043 20.1 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 OAP60651.1 - 0.00056 19.2 0.1 0.89 8.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Arch_ATPase PF01637.13 OAP60651.1 - 0.00064 19.5 0.1 1 9.0 0.0 3.5 3 1 1 4 4 4 1 Archaeal ATPase AAA_11 PF13086.1 OAP60651.1 - 0.00064 19.3 0.2 0.56 9.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 OAP60651.1 - 0.00066 19.1 0.0 1.6 8.2 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain ATP-synt_ab PF00006.20 OAP60651.1 - 0.00085 18.8 0.0 0.65 9.4 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 OAP60651.1 - 0.0043 16.0 0.0 0.27 10.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 OAP60651.1 - 0.007 15.9 0.0 0.83 9.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 OAP60651.1 - 0.0071 15.2 0.6 1.3 7.8 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AFG1_ATPase PF03969.11 OAP60651.1 - 0.019 13.8 0.1 0.5 9.1 0.0 2.8 3 0 0 3 3 3 0 AFG1-like ATPase DAP3 PF10236.4 OAP60651.1 - 0.02 13.8 0.0 11 4.8 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Bac_DnaA PF00308.13 OAP60651.1 - 0.023 14.3 0.0 16 5.0 0.0 3.4 3 1 0 3 3 3 0 Bacterial dnaA protein Guanylate_kin PF00625.16 OAP60651.1 - 0.024 14.0 1.5 1.5 8.2 0.0 3.8 3 2 1 4 4 4 0 Guanylate kinase DUF2075 PF09848.4 OAP60651.1 - 0.027 13.4 0.1 0.92 8.4 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 OAP60651.1 - 0.045 13.4 0.1 19 4.9 0.0 3.2 2 1 1 3 3 3 0 NTPase AAA_24 PF13479.1 OAP60651.1 - 0.046 13.2 0.1 6.9 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.5 OAP60651.1 - 0.085 12.7 0.0 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain AAA_23 PF13476.1 OAP60651.1 - 0.12 12.6 5.9 2.5 8.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain DUF4260 PF14079.1 OAP60652.1 - 5.8e-42 142.1 0.2 6.6e-42 141.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4260) Ank_5 PF13857.1 OAP60653.1 - 7.8e-18 64.0 0.1 7.1e-12 45.1 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) VPS9 PF02204.13 OAP60653.1 - 8.5e-15 54.6 0.0 2.6e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 OAP60653.1 - 4.9e-13 49.2 0.1 4.7e-05 23.6 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAP60653.1 - 1.2e-09 37.4 0.0 0.00027 20.5 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAP60653.1 - 2.1e-09 37.6 0.1 0.0025 18.2 0.0 5.1 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP60653.1 - 5.2e-09 35.4 0.4 0.043 14.0 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat PX PF00787.19 OAP60653.1 - 1.2e-05 25.0 2.3 1.3e-05 24.9 0.2 2.1 2 0 0 2 2 2 1 PX domain DUF447 PF04289.7 OAP60653.1 - 0.07 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Inhibitor_I78 PF11720.3 OAP60654.1 - 4.8e-12 45.4 0.0 6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 OAP60654.1 - 0.00028 20.9 0.0 0.00039 20.5 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family FTP PF07504.8 OAP60654.1 - 0.09 12.2 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Tim44 PF04280.10 OAP60655.1 - 3.7e-32 111.3 0.0 7.3e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain PBP_sp32 PF07222.7 OAP60655.1 - 9.8 5.2 16.1 0.059 12.5 3.5 2.3 3 0 0 3 3 3 0 Proacrosin binding protein sp32 Ribosomal_S11 PF00411.14 OAP60656.1 - 1.4e-06 28.4 0.4 0.0082 16.3 0.0 2.9 3 0 0 3 3 3 2 Ribosomal protein S11 Sporozoite_P67 PF05642.6 OAP60656.1 - 0.066 11.0 0.4 0.1 10.4 0.1 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RIC1 PF07064.8 OAP60657.1 - 1.4e-74 250.8 0.0 2e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 OAP60657.1 - 0.0016 18.2 2.0 1.7 8.6 0.2 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat M16C_assoc PF08367.6 OAP60657.1 - 0.3 9.9 0.0 0.48 9.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase M16C associated Sigma54_AID PF00309.15 OAP60658.1 - 0.091 12.2 0.1 0.091 12.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Abhydrolase_3 PF07859.8 OAP60659.1 - 2.3e-48 164.5 0.0 3.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP60659.1 - 5.4e-07 28.7 0.0 1.2e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 OAP60659.1 - 3.1e-05 23.9 0.1 4.5e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP60659.1 - 5.5e-05 22.4 0.0 0.00054 19.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP60659.1 - 8e-05 22.4 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAP60659.1 - 0.15 10.5 0.0 0.3 9.5 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Sugar_tr PF00083.19 OAP60660.1 - 1.9e-63 214.5 23.4 2.4e-63 214.2 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60660.1 - 5.6e-17 61.4 24.2 1.6e-16 59.9 12.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AcetylCoA_hydro PF02550.10 OAP60662.1 - 2.1e-51 174.5 0.0 3.3e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 OAP60662.1 - 8.4e-40 135.9 0.0 1.4e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SBP56 PF05694.6 OAP60663.1 - 1.4e-195 650.1 0.0 1.7e-195 649.9 0.0 1.1 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Sugar_tr PF00083.19 OAP60663.1 - 7.8e-82 275.2 20.6 9.9e-82 274.8 14.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60663.1 - 2e-12 46.4 35.0 3.5e-10 39.1 5.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LVIVD PF08309.6 OAP60663.1 - 0.0045 15.9 0.0 0.012 14.5 0.0 1.7 1 0 0 1 1 1 1 LVIVD repeat DUF1228 PF06779.9 OAP60663.1 - 0.0076 16.2 3.5 0.24 11.4 0.4 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) SET PF00856.23 OAP60664.1 - 2.1e-06 28.1 0.1 2.1e-06 28.1 0.0 2.9 3 2 0 3 3 3 1 SET domain PHD PF00628.24 OAP60664.1 - 9.5e-05 22.0 10.7 0.00018 21.0 7.4 1.5 1 0 0 1 1 1 1 PHD-finger FGGY_C PF02782.11 OAP60665.1 - 9.8e-49 165.6 0.1 1.6e-48 164.9 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 OAP60665.1 - 1.2e-21 77.1 0.2 4.7e-20 71.9 0.1 2.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain zf-RING_2 PF13639.1 OAP60666.1 - 2.4e-12 46.4 3.9 3.9e-12 45.8 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAP60666.1 - 4.9e-07 29.2 2.1 8e-07 28.6 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP60666.1 - 1.7e-06 27.9 2.5 2.7e-06 27.2 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAP60666.1 - 1.8e-05 24.7 5.4 4.5e-05 23.4 3.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 OAP60666.1 - 2e-05 24.2 1.7 3.3e-05 23.5 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PIG-L PF02585.12 OAP60666.1 - 0.00068 20.1 0.0 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase zf-C3HC4_3 PF13920.1 OAP60666.1 - 0.006 16.2 1.6 0.011 15.3 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAP60666.1 - 0.0068 16.1 1.2 0.014 15.0 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 OAP60666.1 - 0.0072 16.1 0.6 0.014 15.2 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 OAP60666.1 - 0.009 15.8 1.5 0.018 14.9 1.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 OAP60666.1 - 0.014 15.0 1.2 0.032 13.8 0.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 OAP60666.1 - 0.028 14.4 4.1 0.053 13.5 2.9 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 OAP60666.1 - 0.061 13.0 3.0 0.12 12.1 2.1 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 OAP60666.1 - 3.5 7.6 5.0 12 5.9 3.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain HSP20 PF00011.16 OAP60668.1 - 1.2e-08 34.7 0.0 1.4e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family PIH1 PF08190.7 OAP60668.1 - 0.17 11.3 2.4 0.81 9.0 1.7 2.0 1 1 0 1 1 1 0 pre-RNA processing PIH1/Nop17 FAP PF07174.6 OAP60668.1 - 0.23 10.7 9.4 0.3 10.3 6.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF2360 PF10152.4 OAP60668.1 - 0.48 10.7 3.1 0.66 10.2 2.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Neogenin_C PF06583.7 OAP60669.1 - 0.00088 18.9 6.9 0.00098 18.7 4.8 1.1 1 0 0 1 1 1 1 Neogenin C-terminus Abhydrolase_9 PF10081.4 OAP60669.1 - 0.05 12.3 4.6 0.068 11.8 3.2 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Zip PF02535.17 OAP60669.1 - 0.056 12.4 2.4 0.051 12.5 1.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PBP_sp32 PF07222.7 OAP60669.1 - 0.37 9.9 3.2 0.51 9.4 2.2 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nucleo_P87 PF07267.6 OAP60669.1 - 1 7.9 4.0 1.1 7.7 2.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SelP_N PF04592.9 OAP60669.1 - 1.2 8.4 8.2 1.7 7.9 5.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF605 PF04652.11 OAP60670.1 - 1.5 8.1 11.2 1.8 7.8 7.8 1.1 1 0 0 1 1 1 0 Vta1 like Cyclase PF04199.8 OAP60671.1 - 1.8e-05 24.5 0.0 3.7e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase RCC1 PF00415.13 OAP60672.1 - 1.8e-48 162.5 8.0 6.7e-09 35.8 0.0 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAP60672.1 - 6.9e-32 108.3 33.1 2.6e-08 33.2 0.7 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat dCMP_cyt_deam_1 PF00383.17 OAP60673.1 - 8e-25 86.4 0.0 1.1e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 OAP60673.1 - 0.0018 18.1 0.7 0.14 12.0 0.1 2.3 1 1 1 2 2 2 2 Bd3614-like deaminase F-box-like PF12937.2 OAP60675.1 - 0.00035 20.2 0.2 0.0054 16.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like ADH_N PF08240.7 OAP60676.1 - 6.7e-26 90.1 0.4 1.9e-25 88.7 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP60676.1 - 1.2e-18 66.9 0.1 2.1e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP60676.1 - 1.5e-10 42.0 0.2 5.6e-10 40.2 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP60676.1 - 0.00085 18.9 0.2 0.0015 18.1 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF849 PF05853.7 OAP60676.1 - 0.0017 17.2 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic protein of unknown function (DUF849) Romo1 PF10247.4 OAP60676.1 - 0.069 13.3 3.3 2.8 8.1 0.1 3.0 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 DapB_N PF01113.15 OAP60676.1 - 0.13 12.1 0.4 0.49 10.3 0.3 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 OAP60676.1 - 2 8.3 5.5 0.27 11.1 0.4 2.2 2 1 0 2 2 2 0 short chain dehydrogenase Aldedh PF00171.17 OAP60677.1 - 2.7e-158 527.1 0.0 3e-158 526.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 OAP60677.1 - 0.00021 20.5 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 OAP60677.1 - 0.067 11.9 0.3 0.12 11.0 0.2 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Tetraspannin PF00335.15 OAP60678.1 - 0.048 12.9 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Tetraspanin family CRPA PF05745.6 OAP60678.1 - 0.063 13.0 0.7 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Mem_trans PF03547.13 OAP60678.1 - 0.07 11.4 1.7 0.44 8.7 0.0 2.1 1 1 1 2 2 2 0 Membrane transport protein Y_phosphatase PF00102.22 OAP60679.1 - 2.7e-61 206.9 0.0 4.6e-60 202.8 0.0 2.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 OAP60679.1 - 6.6e-08 32.8 0.0 1.9e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.15 OAP60679.1 - 0.0041 16.6 0.1 0.0086 15.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 OAP60679.1 - 0.012 15.9 0.1 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Zip PF02535.17 OAP60679.1 - 6.3 5.7 4.8 10 5.0 3.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter COX16 PF14138.1 OAP60680.1 - 9.6e-27 92.9 0.1 1.3e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 HET PF06985.6 OAP60681.1 - 4.9e-10 39.7 0.0 4.9e-06 26.7 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HLH PF00010.21 OAP60682.1 - 9.4e-09 34.8 0.0 2.1e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4171 PF13775.1 OAP60682.1 - 0.029 14.5 4.7 0.043 13.9 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Host_attach PF10116.4 OAP60682.1 - 0.12 12.5 0.4 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein required for attachment to host cells MARVEL PF01284.18 OAP60684.1 - 0.00015 21.5 14.9 0.00024 20.9 10.2 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF4131 PF13567.1 OAP60684.1 - 0.72 9.2 3.0 1.9 7.8 2.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Zn_clus PF00172.13 OAP60685.1 - 2.5e-08 33.6 11.5 4.5e-08 32.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A2M_comp PF07678.9 OAP60685.1 - 0.052 12.7 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 A-macroglobulin complement component Nic96 PF04097.9 OAP60686.1 - 5.1e-174 579.8 0.0 6.3e-174 579.5 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 OPT PF03169.10 OAP60687.1 - 1e-204 681.5 37.5 1.3e-204 681.2 26.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fe-ADH PF00465.14 OAP60689.1 - 1.2e-66 224.8 0.0 1.6e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAP60689.1 - 2.6e-08 33.5 0.1 0.00079 18.8 0.0 2.2 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase AA_permease PF00324.16 OAP60691.1 - 8.7e-101 337.6 37.3 1.1e-100 337.3 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP60691.1 - 8.5e-24 83.8 40.6 1.1e-23 83.5 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 OAP60691.1 - 0.2 11.3 10.9 0.11 12.2 1.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Dabb PF07876.7 OAP60692.1 - 1.1e-18 67.4 0.0 1.2e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3638 PF12340.3 OAP60693.1 - 9.3e-97 322.5 0.0 2e-96 321.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 OAP60693.1 - 3.2e-11 42.1 0.0 6.5e-11 41.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Lyase_aromatic PF00221.14 OAP60694.1 - 2.6e-150 501.0 0.4 1.4e-97 327.1 0.2 2.1 1 1 1 2 2 2 2 Aromatic amino acid lyase Beta-lactamase PF00144.19 OAP60695.1 - 2.1e-42 145.3 0.0 3.3e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 OAP60695.1 - 0.0083 15.4 0.0 0.048 12.9 0.0 1.9 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.1 OAP60695.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family PAM2 PF07145.10 OAP60696.1 - 0.001 18.3 15.0 1.8 8.2 0.0 5.0 4 0 0 4 4 4 3 Ataxin-2 C-terminal region Thioredoxin_6 PF13848.1 OAP60697.1 - 2.8e-20 72.8 0.1 5.3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Fungal_trans_2 PF11951.3 OAP60697.1 - 3e-09 35.9 0.1 4.6e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy PF03171.15 OAP60698.1 - 0.00077 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 OAP60698.1 - 0.005 17.3 0.1 0.062 13.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.21 OAP60699.1 - 3.8e-34 117.1 0.0 5.3e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PIR PF00399.14 OAP60700.1 - 0.053 12.8 0.1 0.053 12.8 0.1 2.9 3 0 0 3 3 3 0 Yeast PIR protein repeat MMgT PF10270.4 OAP60701.1 - 2e-29 102.1 0.0 2.3e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter PEX11 PF05648.9 OAP60702.1 - 5.3e-22 78.2 0.2 9.8e-22 77.3 0.2 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Pex14_N PF04695.8 OAP60702.1 - 0.015 15.3 0.4 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Synaphin PF05835.7 OAP60702.1 - 0.067 13.3 0.4 0.097 12.8 0.3 1.2 1 0 0 1 1 1 0 Synaphin protein Phosphoesterase PF04185.9 OAP60703.1 - 2.9e-60 204.4 5.0 1.8e-59 201.8 3.5 1.9 1 1 0 1 1 1 1 Phosphoesterase family Antimicrobial10 PF08105.6 OAP60703.1 - 0.0048 16.5 0.7 1.8 8.2 0.1 2.4 2 0 0 2 2 2 2 Metchnikowin family VIT1 PF01988.14 OAP60704.1 - 1.8e-58 197.5 4.3 2.4e-58 197.1 3.0 1.1 1 0 0 1 1 1 1 VIT family MARVEL PF01284.18 OAP60704.1 - 0.042 13.6 1.8 0.071 12.9 1.3 1.4 1 0 0 1 1 1 0 Membrane-associating domain FIST PF08495.5 OAP60704.1 - 0.19 10.8 0.1 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 FIST N domain Phosphoesterase PF04185.9 OAP60705.1 - 5.9e-37 127.7 3.2 1.1e-36 126.8 2.2 1.4 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.10 OAP60706.1 - 1e-44 151.0 2.9 6e-44 148.5 0.5 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 OAP60706.1 - 2e-41 141.5 0.9 3.1e-40 137.6 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP60706.1 - 4.4e-35 120.2 9.2 1.7e-33 115.0 0.5 3.9 3 1 0 3 3 3 2 Multicopper oxidase Glyco_hydro_17 PF00332.13 OAP60707.1 - 4.1e-19 68.7 0.2 6.6e-19 68.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF3405 PF11885.3 OAP60708.1 - 1.9e-211 702.6 1.5 2.3e-211 702.3 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Cupin_2 PF07883.6 OAP60709.1 - 4.3e-07 29.3 0.0 6.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 OAP60709.1 - 0.044 13.1 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) MFS_1 PF07690.11 OAP60710.1 - 6e-37 127.1 29.5 9.1e-37 126.5 20.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAP60710.1 - 0.044 13.2 4.2 0.038 13.4 1.3 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 CoA_trans PF01144.18 OAP60712.1 - 2.8e-100 333.9 2.3 3.1e-58 196.5 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 OAP60712.1 - 0.0021 17.7 0.2 0.0041 16.7 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mito_carr PF00153.22 OAP60713.1 - 1e-49 166.1 0.5 1.5e-16 59.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glycoamylase PF10091.4 OAP60713.1 - 0.053 12.5 0.1 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative glucoamylase Fungal_trans PF04082.13 OAP60714.1 - 6.9e-08 31.6 0.2 1.5e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60714.1 - 2.6e-07 30.4 7.8 5e-07 29.5 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 OAP60714.1 - 8.8 6.5 10.9 28 4.9 7.6 1.8 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region bZIP_1 PF00170.16 OAP60715.1 - 1.2e-07 31.5 15.3 2.1e-07 30.8 10.0 1.7 1 1 1 2 2 2 1 bZIP transcription factor ATG16 PF08614.6 OAP60715.1 - 0.001 18.9 8.5 0.0014 18.4 5.9 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF724 PF05266.9 OAP60715.1 - 0.0014 18.2 6.7 0.0023 17.5 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 OAP60715.1 - 0.0016 18.1 6.3 0.0019 17.9 3.9 1.4 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF869 PF05911.6 OAP60715.1 - 0.0021 16.3 1.8 0.0026 16.0 1.2 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 OAP60715.1 - 0.0024 17.6 6.8 0.0038 16.9 4.7 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein OEP PF02321.13 OAP60715.1 - 0.0025 17.4 5.7 0.0034 16.9 3.9 1.3 1 0 0 1 1 1 1 Outer membrane efflux protein DUF3450 PF11932.3 OAP60715.1 - 0.0026 17.0 4.4 0.0026 17.0 3.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) bZIP_2 PF07716.10 OAP60715.1 - 0.0056 16.4 20.8 0.097 12.5 10.3 2.2 1 1 1 2 2 2 2 Basic region leucine zipper ADIP PF11559.3 OAP60715.1 - 0.014 15.3 11.7 0.015 15.2 7.5 1.5 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding DUF1978 PF09321.5 OAP60715.1 - 0.017 14.5 10.1 0.059 12.7 6.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) COG7 PF10191.4 OAP60715.1 - 0.018 12.9 5.1 0.025 12.5 3.6 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Atg14 PF10186.4 OAP60715.1 - 0.019 13.9 7.7 0.032 13.1 5.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 OAP60715.1 - 0.02 13.9 4.2 0.023 13.7 2.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 OAP60715.1 - 0.027 14.0 9.9 0.041 13.4 6.9 1.3 1 0 0 1 1 1 0 IncA protein DUF4618 PF15397.1 OAP60715.1 - 0.028 13.7 5.6 0.04 13.2 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4613 PF15390.1 OAP60715.1 - 0.029 12.5 3.5 0.031 12.4 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) CAF-1_p150 PF11600.3 OAP60715.1 - 0.037 13.4 9.9 0.052 12.9 6.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 OAP60715.1 - 0.039 12.2 6.6 0.043 12.1 4.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Fib_alpha PF08702.5 OAP60715.1 - 0.041 13.9 9.6 0.029 14.4 5.4 1.6 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family DUF3323 PF11796.3 OAP60715.1 - 0.047 13.0 0.5 0.06 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) HemX PF04375.9 OAP60715.1 - 0.056 12.0 6.2 0.078 11.5 4.3 1.2 1 0 0 1 1 1 0 HemX M_domain PF12938.2 OAP60715.1 - 0.058 13.2 3.6 0.12 12.2 2.5 1.4 1 0 0 1 1 1 0 M domain of GW182 DUF342 PF03961.8 OAP60715.1 - 0.062 11.7 1.6 0.078 11.3 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 OAP60715.1 - 0.071 13.1 3.7 0.12 12.3 2.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.8 OAP60715.1 - 0.073 12.1 3.9 0.098 11.7 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Effector_1 PF04518.7 OAP60715.1 - 0.097 11.6 5.4 0.16 10.9 3.7 1.4 1 1 0 1 1 1 0 Effector from type III secretion system RmuC PF02646.11 OAP60715.1 - 0.11 11.3 5.3 0.079 11.7 2.4 1.7 2 1 0 2 2 2 0 RmuC family Ax_dynein_light PF10211.4 OAP60715.1 - 0.11 12.3 8.3 0.2 11.4 5.8 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain SOBP PF15279.1 OAP60715.1 - 0.15 12.4 6.2 0.17 12.2 4.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein bZIP_Maf PF03131.12 OAP60715.1 - 0.19 12.0 16.5 0.33 11.2 11.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 OAP60715.1 - 0.21 9.3 2.5 0.25 9.1 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family U1snRNP70_N PF12220.3 OAP60715.1 - 0.21 11.9 4.4 0.51 10.7 3.1 1.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TMF_TATA_bd PF12325.3 OAP60715.1 - 0.23 11.2 8.1 1 9.1 5.8 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DDHD PF02862.12 OAP60715.1 - 0.59 9.8 7.4 0.77 9.5 5.2 1.3 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.1 OAP60715.1 - 0.6 9.0 7.1 0.46 9.3 3.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin PF00804.20 OAP60715.1 - 0.61 10.2 8.7 0.049 13.7 1.4 2.1 1 1 1 2 2 2 0 Syntaxin Bap31 PF05529.7 OAP60715.1 - 0.72 9.2 6.0 1 8.7 4.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like HJURP_C PF12347.3 OAP60715.1 - 0.83 9.2 5.6 2 8.0 3.1 2.2 2 1 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF3682 PF12446.3 OAP60715.1 - 0.83 9.9 4.5 1.2 9.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DivIC PF04977.10 OAP60715.1 - 1.3 8.5 12.5 0.19 11.2 2.2 2.3 1 1 1 2 2 2 0 Septum formation initiator FadA PF09403.5 OAP60715.1 - 2.2 8.2 7.5 4 7.4 3.9 1.9 2 0 0 2 2 2 0 Adhesion protein FadA DUF4200 PF13863.1 OAP60715.1 - 2.5 8.0 15.5 2.8 7.8 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF2058 PF09831.4 OAP60715.1 - 3.9 7.3 11.1 5.7 6.7 7.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Mnd1 PF03962.10 OAP60715.1 - 9.8 5.7 12.3 29 4.2 8.5 1.8 1 1 0 1 1 1 0 Mnd1 family DUF4131 PF13567.1 OAP60716.1 - 0.31 10.4 3.2 0.76 9.1 2.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Glycophorin_A PF01102.13 OAP60716.1 - 0.55 10.0 6.2 1.6 8.5 4.3 1.8 1 1 0 1 1 1 0 Glycophorin A Rcd1 PF04078.8 OAP60717.1 - 1.9e-123 410.4 0.5 1.1e-122 407.9 0.3 1.9 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like SbcCD_C PF13558.1 OAP60717.1 - 0.02 14.7 2.4 0.026 14.4 0.9 1.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Ribosomal_60s PF00428.14 OAP60717.1 - 4.6 7.7 7.7 9.2 6.7 5.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein ThylakoidFormat PF11264.3 OAP60717.1 - 7.7 6.0 7.5 25 4.3 4.0 2.5 2 1 0 2 2 2 0 Thylakoid formation protein Aldo_ket_red PF00248.16 OAP60718.1 - 1e-58 198.4 0.0 1.2e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DbpA PF03880.10 OAP60718.1 - 0.11 12.1 0.0 0.36 10.5 0.0 1.9 1 0 0 1 1 1 0 DbpA RNA binding domain DUF2256 PF10013.4 OAP60719.1 - 0.053 13.2 4.7 0.18 11.5 3.2 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4129 PF13559.1 OAP60719.1 - 0.2 11.6 2.9 1.2 9.1 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4129) Fungal_trans_2 PF11951.3 OAP60720.1 - 6e-07 28.3 0.8 6e-07 28.3 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MdoG PF04349.7 OAP60720.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG Sugar_tr PF00083.19 OAP60721.1 - 7.3e-65 219.2 22.8 8.8e-65 219.0 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60721.1 - 1.9e-21 76.1 27.8 7e-18 64.4 11.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease_C PF13906.1 OAP60721.1 - 0.041 13.7 2.8 0.066 13.0 0.5 2.5 2 0 0 2 2 2 0 C-terminus of AA_permease zf-C2H2_4 PF13894.1 OAP60722.1 - 8.2e-07 28.9 10.1 5.9e-05 23.1 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP60722.1 - 1.1e-05 25.5 11.5 0.00018 21.6 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP60722.1 - 4.6e-05 23.5 2.2 4.6e-05 23.5 1.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 OAP60722.1 - 6e-05 23.0 9.3 0.00092 19.3 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAP60722.1 - 0.02 15.0 1.8 0.02 15.0 1.2 2.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF1178 PF06676.6 OAP60722.1 - 0.07 13.3 1.9 0.13 12.4 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) zf-Di19 PF05605.7 OAP60722.1 - 0.26 11.4 4.9 0.52 10.4 3.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FAD_binding_3 PF01494.14 OAP60725.1 - 4.2e-22 78.6 0.0 8.1e-22 77.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP60725.1 - 2.2e-09 36.6 1.8 4.4e-06 25.8 0.7 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP60725.1 - 3.4e-06 26.9 0.8 1.1e-05 25.2 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP60725.1 - 3.6e-06 27.0 0.9 2e-05 24.5 0.6 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP60725.1 - 3.9e-06 26.0 0.2 1.3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP60725.1 - 4.9e-06 25.6 1.2 4.9e-06 25.6 0.8 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAP60725.1 - 8.6e-06 26.0 0.1 0.00037 20.8 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP60725.1 - 4.7e-05 22.0 0.6 0.004 15.6 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 OAP60725.1 - 0.0002 20.1 0.3 0.01 14.5 0.1 2.5 2 1 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.12 OAP60725.1 - 0.0042 16.2 0.7 0.0061 15.6 0.5 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 OAP60725.1 - 0.0054 15.6 2.2 0.011 14.6 1.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAP60725.1 - 0.0067 16.5 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP60725.1 - 0.011 14.7 0.2 1.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 OAP60725.1 - 0.012 15.4 0.3 0.088 12.5 0.1 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 OAP60725.1 - 0.016 14.8 0.2 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 OAP60725.1 - 0.049 12.7 0.5 0.43 9.6 0.5 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF2564 PF10819.3 OAP60725.1 - 0.058 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) UDPG_MGDP_dh_N PF03721.9 OAP60725.1 - 0.22 10.8 0.3 0.37 10.1 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain bZIP_2 PF07716.10 OAP60726.1 - 0.011 15.5 15.9 0.15 11.8 10.4 2.2 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 OAP60726.1 - 0.022 14.7 19.0 3.1 7.8 13.2 2.3 1 1 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.8 OAP60726.1 - 0.052 13.8 0.6 0.052 13.8 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 OAP60726.1 - 0.064 13.5 15.7 0.11 12.8 10.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Methyltransf_23 PF13489.1 OAP60727.1 - 1.8e-14 53.7 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP60727.1 - 5.3e-07 30.0 0.0 1.4e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP60727.1 - 1.2e-06 29.0 0.0 1.8e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP60727.1 - 3.6e-06 27.3 0.0 6.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP60727.1 - 4.9e-05 22.9 0.0 0.00016 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP60727.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 OAP60727.1 - 0.14 11.0 0.0 12 4.6 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase Ubie_methyltran PF01209.13 OAP60727.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SLAC1 PF03595.12 OAP60728.1 - 2.6e-104 348.4 53.8 3e-104 348.2 37.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel K1 PF02960.9 OAP60728.1 - 0.031 14.3 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 K1 glycoprotein Oxidored_molyb PF00174.14 OAP60729.1 - 2.5e-55 186.4 0.0 4e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 OAP60729.1 - 9.8e-26 89.9 0.0 2.3e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 OAP60729.1 - 6.5e-10 38.6 0.1 1.2e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Amidase PF01425.16 OAP60730.1 - 1.2e-73 248.5 0.0 1.4e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Zn_clus PF00172.13 OAP60731.1 - 2.5e-05 24.0 14.9 4.1e-05 23.3 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rpp20 PF12328.3 OAP60732.1 - 6.2e-31 106.9 7.9 1e-29 103.0 5.5 2.2 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 OAP60732.1 - 3e-17 61.9 2.3 9.4e-16 57.1 1.6 2.2 1 1 0 1 1 1 1 Alba NOA36 PF06524.7 OAP60732.1 - 2.4 7.3 5.8 4.3 6.5 4.0 1.4 1 0 0 1 1 1 0 NOA36 protein LZ_Tnp_IS66 PF13007.2 OAP60732.1 - 7.9 7.2 9.8 1.2 9.8 1.6 2.8 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Metallophos_2 PF12850.2 OAP60733.1 - 4e-16 59.2 0.0 4.8e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pex2_Pex12 PF04757.9 OAP60734.1 - 0.0092 15.4 0.2 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region TFIIF_beta PF02270.10 OAP60735.1 - 2e-56 191.8 1.5 2.4e-56 191.5 1.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 OAP60735.1 - 0.0048 16.2 0.1 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit 2-Hacid_dh_C PF02826.14 OAP60736.1 - 6.5e-56 188.2 0.0 9.2e-56 187.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP60736.1 - 3.7e-13 49.0 0.0 4.6e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP60736.1 - 3.5e-05 23.7 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 OAP60736.1 - 0.033 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain CTP_transf_2 PF01467.21 OAP60738.1 - 9.7e-18 64.7 0.0 2.1e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase Glutaredoxin PF00462.19 OAP60740.1 - 3.4e-09 36.5 0.2 1.5e-07 31.3 0.1 2.7 1 1 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 OAP60740.1 - 0.013 15.6 0.1 0.11 12.7 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.13 OAP60741.1 - 1.1e-08 34.7 9.9 1.9e-08 34.0 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.7 OAP60742.1 - 3.6e-11 42.4 0.3 6.1e-11 41.6 0.2 1.4 1 0 0 1 1 1 1 U1 zinc finger APG6 PF04111.7 OAP60742.1 - 0.55 9.2 3.4 0.15 11.0 0.4 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 PRELI PF04707.9 OAP60743.1 - 3.8e-43 146.7 0.4 4.4e-43 146.5 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 OAP60743.1 - 0.061 12.9 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Abhydrolase_6 PF12697.2 OAP60744.1 - 2.3e-19 70.2 2.9 9.6e-19 68.1 0.6 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP60744.1 - 3.6e-07 29.9 0.0 5.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP60744.1 - 3.3e-06 26.8 0.0 7.9e-05 22.4 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family CRF PF00473.12 OAP60745.1 - 0.2 11.7 1.2 0.73 9.9 0.8 1.9 1 0 0 1 1 1 0 Corticotropin-releasing factor family PGA2 PF07543.7 OAP60745.1 - 1.4 8.7 7.4 0.18 11.6 2.2 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 SelP_N PF04592.9 OAP60745.1 - 4.3 6.6 8.0 6.9 5.9 5.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Acetyltransf_1 PF00583.19 OAP60746.1 - 7.5e-09 35.4 0.1 1.2e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP60746.1 - 5.3e-07 29.6 0.0 1.2e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP60746.1 - 0.00026 20.8 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 OAP60746.1 - 0.003 17.4 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP60746.1 - 0.0052 16.5 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein CDC45 PF02724.9 OAP60746.1 - 3.9 5.3 6.2 5.7 4.8 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 OAP60746.1 - 9.5 3.9 17.1 13 3.5 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family GST_N_3 PF13417.1 OAP60747.1 - 5.8e-18 64.8 0.0 1.2e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP60747.1 - 3.4e-13 49.3 0.3 7.9e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP60747.1 - 1.2e-08 34.9 0.0 7.9e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP60747.1 - 1.8e-06 27.7 0.1 4.1e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4109 PF13397.1 OAP60747.1 - 0.14 12.5 1.2 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4109) DUF1453 PF07301.6 OAP60748.1 - 0.0052 16.6 1.3 0.006 16.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1453) Pkinase PF00069.20 OAP60749.1 - 1.4e-54 185.0 0.1 3.1e-38 131.4 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP60749.1 - 6.5e-26 90.9 0.2 2e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAP60749.1 - 0.0002 20.4 0.0 0.00046 19.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAP60749.1 - 0.00066 18.8 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP60749.1 - 0.00084 19.1 0.1 0.03 14.0 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 OAP60749.1 - 0.0089 16.5 0.2 0.034 14.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 OAP60749.1 - 0.026 13.3 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 OAP60749.1 - 0.03 13.6 1.0 0.51 9.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family SpoIIIAH PF12685.2 OAP60749.1 - 0.071 12.6 5.0 0.15 11.5 3.5 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Tim54 PF11711.3 OAP60750.1 - 1.1e-132 442.3 0.5 1.3e-132 442.0 0.3 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF3292 PF11696.3 OAP60750.1 - 2.7 5.7 7.5 4.2 5.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CAP_GLY PF01302.20 OAP60751.1 - 2.8e-16 58.9 0.0 5.1e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 OAP60751.1 - 4.2e-12 45.3 25.6 5.9e-05 22.5 2.1 6.5 4 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 OAP60751.1 - 6.8e-09 34.8 19.9 0.065 13.3 0.1 8.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.1 OAP60751.1 - 1.4e-05 24.6 12.8 0.011 15.4 2.6 4.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 OAP60751.1 - 0.00014 21.4 0.0 0.48 9.9 0.0 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 OAP60751.1 - 0.00039 20.0 17.0 0.61 10.3 0.7 7.3 6 1 1 7 7 7 1 Leucine Rich Repeat LRR_7 PF13504.1 OAP60751.1 - 0.00058 19.6 16.9 15 6.3 0.1 7.5 8 0 0 8 8 8 2 Leucine rich repeat Dna2 PF08696.6 OAP60752.1 - 3.7e-63 212.6 0.0 9e-63 211.3 0.0 1.7 2 0 0 2 2 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 OAP60752.1 - 8.4e-51 172.1 0.0 1.4e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAP60752.1 - 4.8e-40 137.6 0.2 5.1e-20 72.0 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 OAP60752.1 - 3.1e-16 59.5 0.0 7.9e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP60752.1 - 3.8e-12 45.7 0.5 2e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Cas_Cas4 PF01930.12 OAP60752.1 - 4.7e-10 39.6 1.2 8.3e-09 35.5 0.7 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 OAP60752.1 - 6.2e-05 22.6 3.6 0.31 10.5 0.0 3.7 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 OAP60752.1 - 0.00022 20.6 0.0 0.00069 19.0 0.0 1.9 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 OAP60752.1 - 0.0004 19.8 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.9 OAP60752.1 - 0.0012 18.4 0.0 0.0039 16.8 0.0 1.9 1 0 0 1 1 1 1 Helicase CbiA PF01656.18 OAP60752.1 - 0.0017 17.8 0.0 0.0039 16.6 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 OAP60752.1 - 0.0018 18.0 0.1 0.0045 16.6 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 OAP60752.1 - 0.0031 17.5 0.1 0.016 15.1 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain T2SE PF00437.15 OAP60752.1 - 0.0055 15.6 0.2 0.046 12.6 0.1 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein DNA_mis_repair PF01119.14 OAP60752.1 - 0.011 15.2 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 DNA mismatch repair protein, C-terminal domain AAA_10 PF12846.2 OAP60752.1 - 0.012 15.0 1.4 0.23 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 OAP60752.1 - 0.027 14.3 0.2 0.12 12.1 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF2075 PF09848.4 OAP60752.1 - 0.027 13.4 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 OAP60752.1 - 0.036 13.0 0.1 0.24 10.3 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase ResIII PF04851.10 OAP60752.1 - 0.047 13.5 0.1 0.15 11.8 0.1 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 OAP60752.1 - 0.066 12.6 0.0 0.066 12.6 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 OAP60752.1 - 0.073 13.2 0.2 0.38 10.8 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 OAP60752.1 - 0.097 12.8 0.1 0.37 11.0 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 OAP60752.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 OAP60752.1 - 0.12 12.0 0.2 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 NTPase SIR2 PF02146.12 OAP60753.1 - 3e-42 144.3 0.0 6.1e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 Sir2 family DUF592 PF04574.8 OAP60753.1 - 3.3e-05 23.4 0.0 5.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) Mito_carr PF00153.22 OAP60754.1 - 1.1e-68 226.9 0.7 2.7e-23 81.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HLH PF00010.21 OAP60755.1 - 4.7e-12 45.4 0.0 1.3e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 OAP60756.1 - 9.4e-33 112.8 15.8 1.2e-32 112.4 10.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 OAP60756.1 - 0.046 12.6 0.6 0.14 11.0 0.4 1.8 1 1 0 1 1 1 0 Peptidase family M50 Claudin_2 PF13903.1 OAP60756.1 - 2.7 7.6 14.2 3.1 7.4 3.6 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ank_5 PF13857.1 OAP60757.1 - 4e-11 42.7 0.3 6.7e-10 38.8 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP60757.1 - 1.2e-08 35.2 0.1 4.2e-08 33.4 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAP60757.1 - 7.1e-06 26.2 0.4 2.9e-05 24.3 0.3 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAP60757.1 - 1.1e-05 24.9 0.5 0.00022 20.8 0.1 2.8 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 OAP60757.1 - 3.1e-05 23.8 1.7 0.00049 20.0 0.2 2.8 3 0 0 3 3 3 1 Ankyrin repeat YejG PF13989.1 OAP60757.1 - 0.081 12.9 0.1 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 YejG-like protein RNA_lig_T4_1 PF09511.5 OAP60758.1 - 9.3e-85 283.5 0.0 2e-84 282.5 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 OAP60758.1 - 8.1e-73 244.7 0.0 1.2e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 OAP60758.1 - 6.1e-49 166.1 0.2 1.1e-48 165.2 0.1 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 OAP60758.1 - 0.0036 18.1 0.0 0.022 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Cyclin_N PF00134.18 OAP60759.1 - 6.7e-46 154.9 0.0 1.9e-44 150.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAP60759.1 - 1.3e-31 108.9 0.1 2.5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.18 OAP60760.1 - 1.2e-19 70.6 0.1 1.9e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAP60760.1 - 4.5e-06 26.8 0.1 1.2e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 OAP60760.1 - 0.14 11.8 0.4 0.36 10.4 0.3 1.9 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.13 OAP60761.1 - 3.5e-10 39.7 0.1 4e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 OAP60761.1 - 6.8e-09 35.7 0.0 1.7e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 OAP60761.1 - 0.0011 18.4 0.0 0.011 15.2 0.0 2.3 3 0 0 3 3 3 1 DNA methylase RWD PF05773.17 OAP60762.1 - 3.8e-21 75.0 0.0 6.8e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain Mpp10 PF04006.7 OAP60763.1 - 9.8e-86 288.4 68.3 3.9e-83 279.8 47.5 2.7 1 1 1 2 2 2 1 Mpp10 protein SPX PF03105.14 OAP60764.1 - 1.1e-14 54.8 11.3 8.5e-14 51.9 1.3 3.9 2 1 0 3 3 3 1 SPX domain VTC PF09359.5 OAP60764.1 - 0.00085 18.4 0.6 0.21 10.5 0.0 2.7 2 1 0 2 2 2 1 VTC domain Voltage_CLC PF00654.15 OAP60765.1 - 1.4e-87 293.9 19.0 1.4e-87 293.9 13.2 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 OAP60765.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 CBS domain PDR_assoc PF08370.6 OAP60765.1 - 0.049 13.1 0.3 0.18 11.3 0.2 2.0 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Sulfate_transp PF00916.15 OAP60766.1 - 2e-39 135.2 5.1 4.8e-39 134.0 3.6 1.7 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 OAP60766.1 - 1.7e-15 56.5 0.0 3.2e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 OAP60766.1 - 1.4e-13 50.3 0.1 2.4e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 STAS domain PH_6 PF15406.1 OAP60767.1 - 2.5e-33 114.4 4.2 2.5e-33 114.4 2.9 3.4 4 0 0 4 4 4 1 Pleckstrin homology domain PH PF00169.24 OAP60767.1 - 0.0057 16.8 0.3 0.022 14.9 0.0 2.2 2 1 0 2 2 2 1 PH domain bZIP_2 PF07716.10 OAP60768.1 - 2e-08 33.9 7.2 3.3e-08 33.2 5.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 OAP60768.1 - 1.3e-05 25.0 7.2 2.1e-05 24.3 5.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor zf-H2C2_2 PF13465.1 OAP60769.1 - 1.3e-09 37.9 5.0 1.3e-06 28.4 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAP60769.1 - 3.6e-07 30.1 4.2 3.4e-05 23.9 0.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP60769.1 - 5.8e-05 23.1 6.5 0.0026 17.9 0.1 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 OAP60769.1 - 0.13 12.5 1.7 13 6.1 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAP60769.1 - 2 8.6 0.0 2 8.6 0.0 3.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FAD_binding_3 PF01494.14 OAP60770.1 - 2.8e-25 89.1 0.6 1.4e-24 86.7 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP60770.1 - 2.3e-12 46.5 6.1 1.1e-05 24.5 0.1 2.7 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAP60770.1 - 3.1e-07 29.3 1.0 0.016 13.8 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 OAP60770.1 - 1.2e-05 25.2 0.2 7.5e-05 22.6 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP60770.1 - 2.5e-05 23.3 0.8 0.13 11.2 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 OAP60770.1 - 9.8e-05 21.5 0.1 0.0018 17.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP60770.1 - 0.00016 21.6 0.0 0.00016 21.6 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP60770.1 - 0.00024 19.6 0.7 0.0024 16.3 0.5 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 OAP60770.1 - 0.00069 19.9 0.7 1.1 9.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP60770.1 - 0.0016 17.3 0.9 0.003 16.4 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP60770.1 - 0.0016 18.5 0.0 0.018 15.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 OAP60770.1 - 0.0064 15.3 0.0 0.49 9.1 0.0 2.3 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.1 OAP60770.1 - 0.016 15.0 3.8 0.19 11.5 0.1 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF4398 PF14346.1 OAP60770.1 - 0.031 14.3 0.1 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) K_oxygenase PF13434.1 OAP60770.1 - 0.036 12.9 0.0 3 6.6 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 OAP60770.1 - 0.052 12.6 0.1 0.086 11.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family tRNA_SAD PF07973.9 OAP60771.1 - 1.1e-06 28.3 0.8 1.9e-06 27.6 0.5 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 OAP60771.1 - 5.8e-06 24.8 0.0 7.2e-06 24.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) 6PGD PF00393.14 OAP60772.1 - 8.6e-65 218.8 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 OAP60772.1 - 1.1e-33 116.4 0.0 4.4e-33 114.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 OAP60772.1 - 1.5e-05 24.7 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAP60772.1 - 0.00037 19.7 0.1 0.0016 17.5 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 OAP60772.1 - 0.00063 19.5 0.0 0.0019 17.9 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_18 PF12847.2 OAP60772.1 - 0.0032 18.0 0.0 0.0086 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ApbA PF02558.11 OAP60772.1 - 0.0049 16.3 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 OAP60772.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 OAP60772.1 - 0.027 13.4 0.0 0.087 11.7 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 OAP60772.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.19 OAP60773.1 - 1.4e-31 109.4 0.0 2.1e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.11 OAP60774.1 - 3.1e-36 124.8 59.3 1.9e-35 122.2 39.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Lig_chan PF00060.21 OAP60774.1 - 1.7 8.3 8.2 0.083 12.6 0.4 2.5 2 1 0 2 2 2 0 Ligand-gated ion channel CR6_interact PF10147.4 OAP60775.1 - 0.0051 16.1 3.7 0.0064 15.8 2.6 1.1 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Atg14 PF10186.4 OAP60775.1 - 0.0091 14.9 5.8 0.01 14.8 4.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Sec2p PF06428.6 OAP60775.1 - 0.011 15.5 2.4 0.015 15.0 1.6 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p TMF_DNA_bd PF12329.3 OAP60775.1 - 0.013 15.2 1.1 0.023 14.5 0.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 OAP60775.1 - 0.019 14.2 2.7 0.024 13.9 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HAUS6_N PF14661.1 OAP60775.1 - 0.03 13.6 4.2 0.035 13.4 2.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 OAP60775.1 - 0.061 12.3 2.2 0.07 12.1 1.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 FlxA PF14282.1 OAP60775.1 - 0.063 13.2 1.5 0.085 12.8 1.1 1.2 1 0 0 1 1 1 0 FlxA-like protein IncA PF04156.9 OAP60775.1 - 0.075 12.6 4.7 0.096 12.2 3.3 1.1 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 OAP60775.1 - 0.088 12.5 1.5 0.15 11.7 1.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper HCMV_UL139 PF12507.3 OAP60775.1 - 0.2 11.7 6.6 0.53 10.4 4.6 1.6 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein Seryl_tRNA_N PF02403.17 OAP60775.1 - 0.24 11.4 4.2 0.33 10.9 2.9 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 OAP60775.1 - 0.29 10.8 5.3 0.4 10.4 3.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Nop53 PF07767.6 OAP60775.1 - 1.2 8.0 10.0 1.4 7.8 6.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DivIC PF04977.10 OAP60775.1 - 1.4 8.4 7.3 2.3 7.7 3.5 2.0 1 1 1 2 2 2 0 Septum formation initiator FUSC PF04632.7 OAP60775.1 - 9.1 4.5 6.6 9.8 4.4 4.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.1 OAP60775.1 - 9.2 6.7 9.4 35 4.9 6.5 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Adenylsucc_synt PF00709.16 OAP60776.1 - 4.6e-145 483.4 0.0 1.8e-144 481.5 0.0 1.7 1 1 0 1 1 1 1 Adenylosuccinate synthetase CFEM PF05730.6 OAP60777.1 - 0.95 9.3 5.3 0.7 9.7 0.6 2.2 2 0 0 2 2 2 0 CFEM domain AAA_17 PF13207.1 OAP60778.1 - 1.5e-05 25.8 0.5 5.2e-05 24.0 0.4 2.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 OAP60778.1 - 3.9e-05 23.3 0.0 8e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 OAP60778.1 - 0.00015 21.7 0.0 0.0092 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 OAP60778.1 - 0.00082 19.0 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 OAP60778.1 - 0.0014 18.9 3.2 0.0023 18.2 0.1 2.7 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.17 OAP60778.1 - 0.002 17.0 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 OAP60778.1 - 0.0032 17.6 0.0 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAP60778.1 - 0.0043 16.7 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 OAP60778.1 - 0.0047 17.1 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 OAP60778.1 - 0.0056 16.0 0.2 0.46 9.8 0.0 2.6 3 0 0 3 3 3 1 Thymidylate kinase AAA_23 PF13476.1 OAP60778.1 - 0.021 15.1 2.5 0.053 13.8 1.7 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAP60778.1 - 0.023 14.7 0.1 0.085 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 OAP60778.1 - 0.035 13.8 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 OAP60778.1 - 0.037 13.4 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 OAP60778.1 - 0.037 13.4 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 OAP60778.1 - 0.04 12.8 0.0 0.091 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 OAP60778.1 - 0.044 13.2 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 OAP60778.1 - 0.088 12.7 0.2 0.24 11.3 0.0 1.9 2 1 1 3 3 3 0 AAA domain MBOAT_2 PF13813.1 OAP60780.1 - 2e-19 69.4 3.2 5.7e-19 67.9 2.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Pkinase PF00069.20 OAP60781.1 - 5.5e-70 235.4 0.0 2.5e-69 233.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP60781.1 - 7.9e-50 169.3 0.0 1.4e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP60781.1 - 0.0013 17.7 0.0 0.0044 16.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Proteasom_PSMB PF10508.4 OAP60781.1 - 0.016 13.5 3.8 1.8 6.7 0.6 2.7 1 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Arfaptin PF06456.8 OAP60781.1 - 0.07 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Arfaptin-like domain DUF3425 PF11905.3 OAP60783.1 - 3.6e-21 75.4 3.7 1.8e-19 69.9 2.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) VPS9 PF02204.13 OAP60784.1 - 2.7e-30 104.4 0.0 4.4e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 OAP60784.1 - 2.1e-08 33.4 0.2 1.9e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.16 OAP60785.1 - 1.1e-50 172.5 0.0 1.5e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 OAP60785.1 - 4.1e-07 29.7 0.0 1.1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 OAP60785.1 - 7.2e-05 22.7 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 OAP60785.1 - 0.0047 16.1 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein MFS_1 PF07690.11 OAP60786.1 - 2.6e-37 128.3 75.2 6.2e-34 117.2 33.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP60786.1 - 2.9e-07 29.4 36.5 9.2e-05 21.1 8.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP60787.1 - 1.4e-22 79.9 43.7 1.4e-22 79.9 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.17 OAP60788.1 - 1.9e-13 49.8 0.0 3.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP60788.1 - 1.2e-12 47.5 0.1 2.7e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP60788.1 - 0.00024 20.8 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF812 PF05667.6 OAP60788.1 - 0.32 9.4 2.3 0.4 9.1 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HAP1_N PF04849.8 OAP60788.1 - 1.1 8.1 6.6 1.5 7.7 4.6 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region IncA PF04156.9 OAP60788.1 - 1.6 8.2 5.3 2.2 7.8 3.7 1.1 1 0 0 1 1 1 0 IncA protein HECT PF00632.20 OAP60789.1 - 2.5e-95 319.3 0.0 3.6e-95 318.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 OAP60789.1 - 5.4e-33 112.4 17.9 6.9e-11 41.7 1.2 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 OAP60789.1 - 3e-16 59.0 0.0 6.4e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain LSM PF01423.17 OAP60791.1 - 2e-17 62.4 0.1 2.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.11 OAP60792.1 - 1.9e-28 99.2 34.1 2.1e-28 99.0 23.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2762 PF10960.3 OAP60792.1 - 0.077 12.7 0.5 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) DUF1616 PF07760.6 OAP60792.1 - 0.17 11.0 5.5 0.044 12.9 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF1772 PF08592.6 OAP60792.1 - 4.9 6.8 11.1 1.8 8.2 1.7 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) DUF4231 PF14015.1 OAP60792.1 - 6.2 6.8 8.6 1.3 9.0 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Alpha-amylase PF00128.19 OAP60793.1 - 3.6e-91 305.8 0.4 5.2e-91 305.3 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 OAP60793.1 - 0.00039 19.4 0.0 0.00068 18.6 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_42C PF08533.5 OAP60793.1 - 0.013 15.0 0.2 0.048 13.1 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Alpha-amylase_C PF02806.13 OAP60793.1 - 0.018 15.1 0.0 0.066 13.3 0.0 1.9 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain FAA_hydrolase PF01557.13 OAP60794.1 - 2e-44 151.6 0.0 2.6e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 OAP60794.1 - 1.1e-26 92.8 0.0 1.8e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal p450 PF00067.17 OAP60795.1 - 5.9e-60 203.1 0.0 6.6e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.8 OAP60796.1 - 9.9e-178 590.8 0.1 1.1e-177 590.6 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HLH PF00010.21 OAP60797.1 - 3.4e-13 49.0 0.0 6.7e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4611 PF15387.1 OAP60797.1 - 0.0075 16.3 2.0 0.017 15.2 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) RXT2_N PF08595.6 OAP60797.1 - 0.0085 15.9 1.3 0.017 14.9 0.9 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 OAP60797.1 - 0.057 13.6 12.6 0.11 12.7 8.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAP60797.1 - 0.11 11.9 7.9 0.18 11.3 5.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAP60797.1 - 0.13 11.8 4.7 0.22 11.1 3.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 OAP60797.1 - 3.5 7.9 11.1 0.47 10.7 4.4 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aminotran_4 PF01063.14 OAP60798.1 - 5.5e-26 91.4 0.0 7.9e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase_Tyr PF07714.12 OAP60799.1 - 4.6e-13 48.8 0.0 2.4e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 OAP60799.1 - 2.8e-10 39.8 0.0 5.1e-10 38.9 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Kdo PF06293.9 OAP60799.1 - 0.03 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 OAP60800.1 - 2.2e-18 66.3 0.0 6.1e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP60800.1 - 4.7e-10 38.9 0.0 2.5e-09 36.6 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase MIP PF00230.15 OAP60801.1 - 4.3e-44 150.6 9.8 8.4e-44 149.7 6.8 1.4 1 1 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 OAP60802.1 - 5.1e-27 94.5 32.5 5.1e-27 94.5 22.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 OAP60803.1 - 7.8e-75 251.8 0.0 9.4e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP60803.1 - 1.4e-13 51.5 0.1 3.9e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 OAP60804.1 - 1.6e-23 82.8 3.8 2.6e-23 82.2 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH PF00378.15 OAP60805.1 - 4.3e-23 81.6 0.0 1.1e-22 80.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Glycos_transf_3 PF00591.16 OAP60806.1 - 3.3e-62 210.1 0.0 2.1e-50 171.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 OAP60806.1 - 1.3e-08 34.2 0.0 3.8e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 OAP60807.1 - 1.1e-15 56.7 4.3 1.4e-15 56.3 3.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit RRN7 PF11781.3 OAP60807.1 - 0.0083 15.6 1.7 0.55 9.7 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 OAP60807.1 - 0.014 15.2 0.2 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 OAP60807.1 - 0.02 14.5 0.8 0.028 14.1 0.5 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.5 OAP60807.1 - 0.032 13.6 3.5 1.5 8.3 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain HypA PF01155.14 OAP60807.1 - 0.037 13.7 0.3 0.044 13.4 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family PhnA_Zn_Ribbon PF08274.7 OAP60807.1 - 0.082 12.7 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon TFIIS_C PF01096.13 OAP60807.1 - 0.092 12.3 0.4 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2296 PF10058.4 OAP60807.1 - 0.17 11.6 1.2 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) UPF0547 PF10571.4 OAP60807.1 - 0.36 10.5 2.6 1.2 8.9 1.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 OAP60807.1 - 0.48 10.1 2.4 6.4 6.5 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal DUF164 PF02591.10 OAP60807.1 - 0.48 10.2 3.4 7.7 6.4 2.3 2.1 1 1 0 1 1 1 0 Putative zinc ribbon domain zinc_ribbon_4 PF13717.1 OAP60807.1 - 1.2 8.8 3.5 11 5.8 2.4 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 OAP60807.1 - 9.4 6.5 7.0 5.6 7.2 1.0 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain HET PF06985.6 OAP60808.1 - 2.7e-38 131.2 0.4 5e-38 130.4 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Thaumatin PF00314.12 OAP60809.1 - 0.0014 18.1 2.3 0.43 10.0 0.0 2.8 1 1 1 3 3 3 2 Thaumatin family Bys1 PF04681.7 OAP60809.1 - 0.0017 18.0 2.5 0.0055 16.4 1.8 1.7 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein VIT1 PF01988.14 OAP60810.1 - 1.2e-56 191.5 1.9 1.5e-56 191.3 1.3 1.0 1 0 0 1 1 1 1 VIT family Mod_r PF07200.8 OAP60812.1 - 3.9e-08 33.3 1.3 5.9e-08 32.7 0.9 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.10 OAP60812.1 - 0.28 10.7 1.7 0.92 9.0 0.5 2.1 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 OAP60812.1 - 0.37 10.5 2.6 0.65 9.7 1.2 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ATG16 PF08614.6 OAP60812.1 - 0.57 9.9 7.0 1.4 8.6 1.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) zf-met PF12874.2 OAP60813.1 - 1.5e-05 25.0 1.9 3.7e-05 23.7 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 OAP60813.1 - 0.043 13.0 0.9 0.094 12.0 0.6 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Ank_2 PF12796.2 OAP60815.1 - 6.5e-13 48.8 0.0 1.3e-12 47.9 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAP60815.1 - 1.4e-12 46.7 0.3 8.8e-10 37.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAP60815.1 - 1.9e-12 46.1 0.1 5.8e-07 29.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 OAP60815.1 - 2.5e-11 43.4 0.3 1.4e-07 31.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP60815.1 - 4.8e-11 42.8 0.1 1.9e-07 31.3 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Esterase_phd PF10503.4 OAP60816.1 - 1.9e-13 50.2 0.7 4.1e-12 45.8 0.2 2.2 2 1 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 OAP60816.1 - 4.9e-10 39.3 0.1 6.3e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP60816.1 - 1.6e-06 27.7 0.0 0.00016 21.2 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 OAP60816.1 - 1.3e-05 24.7 0.0 0.00075 19.0 0.0 2.2 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 OAP60816.1 - 1.7e-05 24.7 3.5 0.00026 20.9 0.7 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAP60816.1 - 0.00067 19.2 0.0 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP60816.1 - 0.0018 17.5 3.5 0.07 12.3 0.2 2.9 2 1 1 3 3 3 1 Prolyl oligopeptidase family Esterase PF00756.15 OAP60816.1 - 0.013 14.9 0.1 0.039 13.3 0.1 1.6 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.7 OAP60816.1 - 0.021 13.3 0.4 0.065 11.7 0.1 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 OAP60816.1 - 0.046 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 OAP60816.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2263 PF10021.4 OAP60818.1 - 5.5e-30 104.3 0.0 8.7e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 OAP60818.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Macro domain Enkurin PF13864.1 OAP60819.1 - 0.013 15.7 0.2 0.022 14.9 0.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding DUF3278 PF11683.3 OAP60819.1 - 0.06 13.3 1.8 0.092 12.7 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF3899 PF13038.1 OAP60819.1 - 0.86 9.8 0.0 0.86 9.8 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) Ribosomal_L3 PF00297.17 OAP60820.1 - 3.7e-34 118.3 1.5 2.5e-32 112.3 0.3 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 DUF4267 PF14087.1 OAP60822.1 - 1.7e-16 59.8 4.5 2.2e-16 59.4 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Sugar_tr PF00083.19 OAP60823.1 - 6.8e-52 176.5 25.8 8.9e-52 176.1 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60823.1 - 1.3e-10 40.5 45.8 3.9e-09 35.6 24.8 2.4 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP60823.1 - 0.0042 16.8 6.2 0.51 10.1 0.0 3.4 3 0 0 3 3 3 2 MFS_1 like family Ank_2 PF12796.2 OAP60824.1 - 3.7e-55 184.2 18.7 1.2e-14 54.3 0.1 4.2 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP60824.1 - 7.5e-32 109.1 10.8 2.3e-11 43.8 0.0 6.5 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 OAP60824.1 - 1.2e-26 91.1 11.4 9.7e-05 21.9 0.0 7.9 7 0 0 7 7 7 7 Ankyrin repeat SPX PF03105.14 OAP60824.1 - 5.8e-26 91.8 8.7 2.8e-13 50.2 1.0 2.6 1 1 1 2 2 2 2 SPX domain Ank_3 PF13606.1 OAP60824.1 - 8.3e-21 72.0 10.3 0.0003 20.7 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 OAP60824.1 - 3.5e-18 65.2 12.0 1e-05 25.5 0.1 6.9 3 1 5 8 8 8 6 Ankyrin repeats (many copies) GDPD PF03009.12 OAP60824.1 - 3.9e-07 29.8 0.0 1.4e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DRAT PF07357.6 OAP60824.1 - 0.026 13.7 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Mito_carr PF00153.22 OAP60827.1 - 1.1e-66 220.6 6.3 5.3e-25 86.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1_C PF12936.2 OAP60828.1 - 1.8e-28 98.2 0.4 1.8e-28 98.2 0.3 4.9 4 2 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 OAP60828.1 - 9e-27 93.3 20.1 9e-27 93.3 13.9 5.1 5 1 0 5 5 5 1 KRI1-like family PH PF00169.24 OAP60829.1 - 6.5e-08 32.7 0.2 2e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 OAP60829.1 - 0.00034 20.0 0.0 0.00094 18.6 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Solute_trans_a PF03619.11 OAP60831.1 - 3.6e-55 187.1 6.6 5e-55 186.7 4.5 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Acyl-CoA_dh_1 PF00441.19 OAP60832.1 - 1.2e-33 116.3 4.1 1.9e-33 115.7 2.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP60832.1 - 2.5e-20 71.7 0.7 4.1e-20 71.0 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAP60832.1 - 1.4e-11 44.9 2.9 2e-11 44.4 0.1 2.5 2 2 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAP60832.1 - 4.6e-08 33.3 2.9 8e-08 32.6 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4158 PF13700.1 OAP60832.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) HpcH_HpaI PF03328.9 OAP60833.1 - 8.7e-34 116.3 0.0 1.2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2156 PF09924.4 OAP60833.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) DUF836 PF05768.9 OAP60834.1 - 4.3e-10 39.7 0.2 1.2e-08 35.0 0.1 2.0 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) IPP-2 PF04979.9 OAP60834.1 - 0.015 15.5 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) DUF3164 PF11363.3 OAP60834.1 - 0.027 13.8 0.1 0.036 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) MFS_1 PF07690.11 OAP60835.1 - 4.5e-35 120.9 58.5 1e-32 113.2 24.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 OAP60835.1 - 0.22 11.7 6.6 1.2 9.3 0.1 3.1 3 0 0 3 3 3 0 Divalent cation transporter Fungal_trans PF04082.13 OAP60836.1 - 7.7e-05 21.6 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BCD PF15461.1 OAP60836.1 - 0.093 12.1 0.6 2.6 7.4 0.0 2.8 3 0 0 3 3 3 0 Beta-carotene 15,15'-dioxygenase p450 PF00067.17 OAP60837.1 - 9.5e-62 209.0 0.0 1.2e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4536 PF15055.1 OAP60837.1 - 0.19 11.7 1.5 14 5.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Acetyltransf_1 PF00583.19 OAP60838.1 - 1.2e-10 41.2 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP60838.1 - 2.7e-08 33.8 0.0 1e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP60838.1 - 4.1e-05 23.6 0.0 0.00014 21.9 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP60838.1 - 0.00029 20.7 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP60838.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein End3 PF12761.2 OAP60839.1 - 0.0089 15.6 1.8 0.041 13.5 0.3 2.2 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 DUF3138 PF11336.3 OAP60839.1 - 0.32 9.1 0.1 0.88 7.6 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Anp1 PF03452.9 OAP60841.1 - 3.7e-109 364.0 0.0 4.4e-109 363.7 0.0 1.0 1 0 0 1 1 1 1 Anp1 SART-1 PF03343.8 OAP60842.1 - 0.036 12.4 1.0 0.044 12.1 0.7 1.1 1 0 0 1 1 1 0 SART-1 family Nbs1_C PF08599.5 OAP60842.1 - 0.41 10.5 2.1 3.8 7.4 0.6 2.3 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Sugar_tr PF00083.19 OAP60844.1 - 6.7e-127 423.7 30.1 7.8e-127 423.5 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60844.1 - 8.9e-22 77.2 30.7 6.7e-13 48.0 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TAF1_subA PF14929.1 OAP60844.1 - 0.19 10.1 0.0 0.29 9.5 0.0 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A MscS_TM PF12794.2 OAP60844.1 - 0.68 8.4 7.8 0.16 10.5 0.6 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 MFS_1 PF07690.11 OAP60845.1 - 1e-13 50.7 32.8 1e-13 50.7 22.8 3.8 2 2 1 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.11 OAP60846.1 - 0.00018 20.3 6.6 0.00019 20.2 4.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Barwin PF00967.12 OAP60847.1 - 0.0019 17.8 1.4 0.0029 17.2 1.0 1.3 1 0 0 1 1 1 1 Barwin family ABC1 PF03109.11 OAP60848.1 - 4.1e-30 104.1 0.0 7.3e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Acetyltransf_7 PF13508.1 OAP60848.1 - 1.1e-05 25.4 0.0 3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP60848.1 - 0.0044 17.1 0.1 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP60848.1 - 0.01 15.8 0.0 0.044 13.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF3650 PF12368.3 OAP60848.1 - 0.022 14.2 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) RIO1 PF01163.17 OAP60848.1 - 0.025 13.9 0.0 0.06 12.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Mur_ligase_M PF08245.7 OAP60849.1 - 4.7e-10 39.8 0.0 2.5e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Mur ligase middle domain Acetyltransf_1 PF00583.19 OAP60850.1 - 1e-07 31.8 0.0 3.1e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP60850.1 - 8.1e-07 29.1 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP60850.1 - 0.00053 20.0 0.1 0.0033 17.5 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain EHN PF06441.7 OAP60851.1 - 3.5e-38 129.9 0.1 7.1e-38 128.9 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 OAP60851.1 - 3e-07 30.2 0.0 5.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP60851.1 - 2.7e-06 27.4 0.0 4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mrr_cat PF04471.7 OAP60851.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease Fungal_trans_2 PF11951.3 OAP60852.1 - 5.3e-09 35.1 0.0 7.1e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Choline_kinase PF01633.15 OAP60853.1 - 9.2e-44 149.5 0.0 2.7e-42 144.7 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 OAP60853.1 - 1.8e-08 34.4 0.7 2.5e-08 33.9 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAP60853.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase CPL PF08144.6 OAP60854.1 - 3.8e-20 72.2 0.3 2.7e-18 66.2 0.0 3.5 2 2 2 4 4 4 1 CPL (NUC119) domain PUF PF00806.14 OAP60854.1 - 0.0019 17.5 0.6 1.5 8.4 0.0 3.8 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat Guanylate_kin PF00625.16 OAP60858.1 - 3e-58 196.2 0.0 4.4e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 OAP60858.1 - 9.4e-08 32.0 0.1 7.5e-07 29.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAP60858.1 - 2.3e-05 24.5 0.1 0.00044 20.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP60858.1 - 5.4e-05 23.2 0.0 0.00028 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 OAP60858.1 - 5.5e-05 23.4 0.1 0.00028 21.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 OAP60858.1 - 0.00022 20.4 0.0 0.00044 19.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAP60858.1 - 0.00053 20.7 1.0 0.0024 18.6 0.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 OAP60858.1 - 0.0007 19.5 0.0 0.0064 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 OAP60858.1 - 0.00099 19.4 0.0 0.0017 18.6 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 OAP60858.1 - 0.0016 17.8 0.5 0.0078 15.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 OAP60858.1 - 0.0025 18.0 0.6 0.099 12.8 0.4 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 OAP60858.1 - 0.0094 15.0 0.1 0.024 13.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 OAP60858.1 - 0.019 14.3 0.0 0.045 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 OAP60858.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.12 OAP60858.1 - 0.025 13.9 0.1 1.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase RNA_helicase PF00910.17 OAP60858.1 - 0.026 14.7 0.1 0.098 12.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 OAP60858.1 - 0.046 13.6 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAP60858.1 - 0.051 13.8 3.2 0.2 11.9 2.2 1.9 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 OAP60858.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein DUF1895 PF08988.5 OAP60858.1 - 0.069 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) Rad17 PF03215.10 OAP60858.1 - 0.07 11.8 0.0 0.095 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 OAP60858.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 OAP60858.1 - 0.087 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 OAP60858.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain CPT PF07931.7 OAP60858.1 - 0.11 12.0 0.0 1.4 8.4 0.0 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.16 OAP60858.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SPC22 PF04573.7 OAP60858.1 - 0.13 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Signal peptidase subunit Septin PF00735.13 OAP60859.1 - 1.9e-112 374.9 0.5 2.2e-112 374.6 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 OAP60859.1 - 9.4e-07 28.7 0.0 1.7e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 OAP60859.1 - 3e-06 26.4 0.0 5.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 OAP60859.1 - 1e-05 24.7 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAP60859.1 - 2.7e-05 23.6 0.3 0.0018 17.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 OAP60859.1 - 0.00062 19.6 0.4 0.68 9.7 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 OAP60859.1 - 0.0035 16.8 0.1 0.0035 16.8 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 OAP60859.1 - 0.0049 17.2 0.0 0.0085 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 OAP60859.1 - 0.0083 16.4 0.5 0.013 15.8 0.4 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 OAP60859.1 - 0.011 15.9 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 OAP60859.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 OAP60859.1 - 0.019 13.8 0.0 0.053 12.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Gtr1_RagA PF04670.7 OAP60859.1 - 0.019 14.1 0.0 0.08 12.0 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 OAP60859.1 - 0.023 14.7 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 OAP60859.1 - 0.051 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 OAP60859.1 - 0.087 13.3 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 OAP60859.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 OAP60860.1 - 2.8e-30 103.0 10.5 1.3e-11 43.9 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 OAP60860.1 - 2e-06 27.6 0.0 0.0056 16.4 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAP60860.1 - 7e-05 21.2 0.0 0.00052 18.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome D1 heme domain Ribosomal_L32p PF01783.18 OAP60860.1 - 0.0017 18.4 1.8 0.0034 17.5 1.3 1.5 1 0 0 1 1 1 1 Ribosomal L32p protein family Nup160 PF11715.3 OAP60860.1 - 0.0084 14.2 0.2 0.12 10.4 0.1 2.5 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Lactonase PF10282.4 OAP60860.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Nbas_N PF15492.1 OAP60860.1 - 0.022 13.8 0.3 9 5.3 0.0 3.4 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 OAP60860.1 - 0.063 12.4 0.6 2.1 7.4 0.0 2.8 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF2416 PF10315.4 OAP60861.1 - 0.0089 16.2 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) DUF4536 PF15055.1 OAP60861.1 - 0.16 12.0 1.1 0.4 10.7 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) NdhL PF10716.4 OAP60861.1 - 0.31 10.8 1.6 5 6.9 0.9 2.2 1 1 1 2 2 2 0 NADH dehydrogenase transmembrane subunit DUF1977 PF09320.6 OAP60862.1 - 1.3e-23 83.2 0.0 2.4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 OAP60862.1 - 9e-23 79.7 1.2 1.6e-22 78.9 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain ADP_ribosyl_GH PF03747.9 OAP60862.1 - 0.026 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Ufd2P_core PF10408.4 OAP60863.1 - 4e-194 646.4 11.1 4.8e-194 646.1 7.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 OAP60863.1 - 9.6e-25 86.3 2.6 2.4e-24 85.0 1.1 2.3 2 0 0 2 2 2 1 U-box domain Methyltransf_23 PF13489.1 OAP60864.1 - 1.4e-12 47.6 0.0 3.2e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP60864.1 - 5.1e-08 32.6 0.0 7.2e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP60864.1 - 2e-07 31.5 0.0 3.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP60864.1 - 9.9e-07 29.1 0.0 2.6e-06 27.8 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP60864.1 - 3.1e-06 27.5 0.0 7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP60864.1 - 0.18 10.8 0.0 0.66 9.0 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family NIPSNAP PF07978.8 OAP60865.1 - 8e-28 96.4 0.1 8.9e-28 96.2 0.1 1.0 1 0 0 1 1 1 1 NIPSNAP Peptidase_M19 PF01244.16 OAP60866.1 - 3.2e-98 328.5 0.0 3.8e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Imm42 PF15601.1 OAP60866.1 - 0.049 13.0 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 42 DIOX_N PF14226.1 OAP60867.1 - 1.6e-21 76.9 0.0 2.5e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP60867.1 - 1.6e-19 70.0 0.0 3.7e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MARVEL PF01284.18 OAP60869.1 - 4.4 7.1 9.6 11 5.7 6.6 1.7 1 1 0 1 1 1 0 Membrane-associating domain RRM_1 PF00076.17 OAP60870.1 - 6.8e-15 54.4 0.0 1.8e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP60870.1 - 4.6e-11 42.5 0.0 8.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP60870.1 - 2.1e-10 40.2 0.1 4e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_6 PF13344.1 OAP60870.1 - 0.065 13.1 0.2 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Nup35_RRM_2 PF14605.1 OAP60870.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RTC PF01137.16 OAP60871.1 - 9.1e-34 116.2 0.0 2.3e-22 78.9 0.0 3.4 2 1 0 2 2 2 2 RNA 3'-terminal phosphate cyclase Ricin_B_lectin PF00652.17 OAP60872.1 - 4.2e-19 68.7 0.0 1.1e-06 28.6 0.0 4.2 3 1 1 4 4 4 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 OAP60872.1 - 0.00041 20.6 0.0 2.8 8.3 0.0 4.5 2 2 1 5 5 5 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 OAP60872.1 - 0.011 15.1 3.2 2.2 7.6 0.0 3.9 2 2 2 4 4 4 0 Cytolethal distending toxin A/C family FAD_binding_3 PF01494.14 OAP60873.1 - 9.6e-18 64.3 1.7 2.3e-11 43.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 OAP60873.1 - 2.6e-08 34.1 0.2 9.1e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP60873.1 - 9.2e-07 28.0 2.0 1.5e-05 24.0 0.6 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP60873.1 - 0.0004 20.3 0.2 0.001 19.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP60873.1 - 0.0025 17.7 0.3 0.0057 16.5 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP60873.1 - 0.04 12.7 0.5 0.054 12.3 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 OAP60873.1 - 0.048 13.0 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 OAP60873.1 - 0.049 12.5 1.2 0.057 12.3 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 OAP60873.1 - 0.062 12.8 0.1 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 OAP60873.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 OAP60873.1 - 0.17 11.5 0.2 0.26 10.9 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 OAP60873.1 - 0.49 8.9 2.7 0.68 8.4 0.4 1.9 1 1 0 2 2 2 0 Tryptophan halogenase Peptidase_M49 PF03571.10 OAP60874.1 - 7.3e-229 760.4 0.0 9.2e-229 760.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 ADH_zinc_N PF00107.21 OAP60875.1 - 1.4e-11 44.0 0.1 2.3e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP60875.1 - 1.8e-08 34.0 0.1 3.7e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP60875.1 - 4.3e-05 24.4 0.0 9.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 OAP60876.1 - 2.3e-09 37.0 9.0 3.6e-09 36.3 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP60876.1 - 1.2e-06 27.4 0.2 0.017 13.7 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain E1-E2_ATPase PF00122.15 OAP60877.1 - 3e-48 163.8 3.4 3e-48 163.8 2.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 OAP60877.1 - 3e-23 83.3 0.3 1e-22 81.6 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAP60877.1 - 7.4e-15 55.6 0.0 1.5e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 OAP60877.1 - 3.9e-12 46.1 1.6 5.4e-12 45.6 0.1 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain dsrm PF00035.20 OAP60878.1 - 0.00033 21.1 0.0 0.0008 19.9 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif OTT_1508_deam PF14441.1 OAP60879.1 - 4e-17 62.3 0.0 6.6e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase PBAN PF05874.6 OAP60880.1 - 0.099 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) Abhydrolase_6 PF12697.2 OAP60882.1 - 4.6e-25 88.8 0.0 9.6e-25 87.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP60882.1 - 0.00013 21.7 0.0 0.00017 21.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP60882.1 - 0.00046 19.8 0.0 0.0021 17.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 OAP60882.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PTCB-BRCT PF12738.2 OAP60883.1 - 2.8e-34 116.7 1.6 3.5e-20 71.6 0.2 5.3 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.21 OAP60883.1 - 2e-32 111.1 0.0 4.2e-10 39.6 0.0 6.0 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.7 OAP60884.1 - 8.4e-51 171.5 0.6 1.4e-50 170.8 0.2 1.4 1 1 1 2 2 2 1 ESCRT-II complex subunit alpha-hel2 PF14456.1 OAP60884.1 - 0.068 11.9 0.1 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 Phg_2220_C PF09524.5 OAP60884.1 - 0.073 13.0 0.2 0.3 11.1 0.0 2.0 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) CLAMP PF14769.1 OAP60884.1 - 0.36 11.0 2.5 1.5 9.0 0.5 2.4 2 1 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 PHD PF00628.24 OAP60885.1 - 9.7e-09 34.7 9.2 2e-08 33.7 6.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAP60885.1 - 0.21 10.9 10.6 0.012 14.8 3.7 1.7 2 0 0 2 2 2 0 PHD-finger 2-Hacid_dh_C PF02826.14 OAP60886.1 - 2.4e-34 118.0 0.0 3.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP60886.1 - 2.5e-14 52.8 0.0 3.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NmrA PF05368.8 OAP60887.1 - 3.2e-26 92.0 0.0 3.7e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP60887.1 - 4.1e-06 26.9 0.0 1.3e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP60887.1 - 2.5e-05 23.8 0.1 0.00064 19.2 0.1 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 OAP60887.1 - 0.0049 17.1 0.1 0.033 14.4 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 OAP60887.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 OAP60887.1 - 0.029 13.0 0.2 0.043 12.5 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAP60887.1 - 0.077 12.9 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase S1-P1_nuclease PF02265.11 OAP60888.1 - 4.7e-70 236.0 0.9 5.3e-70 235.9 0.6 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Aconitase PF00330.15 OAP60889.1 - 1.4e-160 534.7 0.0 4.2e-160 533.2 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAP60889.1 - 3.1e-38 130.8 0.0 4.9e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain MACPF PF01823.14 OAP60890.1 - 3.7e-16 59.4 0.3 5.8e-16 58.8 0.2 1.3 1 0 0 1 1 1 1 MAC/Perforin domain Fungal_trans PF04082.13 OAP60891.1 - 7.4e-16 57.8 0.2 1.1e-15 57.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP60891.1 - 0.00011 21.9 7.0 0.00026 20.8 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2408 PF10303.4 OAP60892.1 - 3e-49 166.5 7.5 4.3e-30 104.5 0.9 5.3 2 2 3 5 5 5 3 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.7 OAP60892.1 - 0.00033 20.5 1.3 0.0037 17.1 0.0 3.1 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF241 PF03087.9 OAP60892.1 - 0.0072 15.8 0.4 0.0072 15.8 0.3 1.8 2 0 0 2 2 2 1 Arabidopsis protein of unknown function DUF4631 PF15450.1 OAP60892.1 - 0.0089 14.3 4.8 0.0098 14.2 0.3 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4631) Spc24 PF08286.6 OAP60892.1 - 0.015 15.0 2.6 0.41 10.3 0.0 2.8 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 GvpG PF05120.7 OAP60892.1 - 0.015 15.0 1.7 2.2 8.1 0.0 3.4 3 0 0 3 3 3 0 Gas vesicle protein G HisKA_3 PF07730.8 OAP60892.1 - 0.021 15.1 1.4 0.52 10.7 0.1 3.3 3 0 0 3 3 3 0 Histidine kinase XhlA PF10779.4 OAP60892.1 - 0.044 13.6 3.0 9.7 6.1 0.1 3.2 3 0 0 3 3 3 0 Haemolysin XhlA PTRF_SDPR PF15237.1 OAP60892.1 - 0.057 12.8 0.2 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 PTRF/SDPR family Band_7 PF01145.20 OAP60892.1 - 0.085 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 SPFH domain / Band 7 family FUSC PF04632.7 OAP60892.1 - 0.086 11.2 0.5 0.12 10.8 0.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HR1 PF02185.11 OAP60892.1 - 0.13 12.0 8.9 0.62 9.8 1.7 3.4 3 1 0 3 3 3 0 Hr1 repeat DUF4201 PF13870.1 OAP60892.1 - 0.18 11.2 11.4 0.28 10.6 0.6 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 OAP60892.1 - 1.6 9.0 6.1 4 7.7 0.0 3.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.15 OAP60892.1 - 9.7 6.0 10.9 2.9 7.7 0.1 3.5 4 1 0 4 4 4 0 Prefoldin subunit Glyco_hydro_88 PF07470.8 OAP60893.1 - 7.8e-12 44.8 0.0 1.3e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Amidohydro_3 PF07969.6 OAP60894.1 - 2.8e-32 112.4 3.3 3.5e-32 112.1 2.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 OAP60894.1 - 3.1e-06 27.1 1.5 0.00017 21.3 0.2 2.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP60894.1 - 5.5e-06 26.1 0.1 2.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 OAP60894.1 - 0.00077 19.5 1.0 0.18 11.7 0.1 2.6 2 0 0 2 2 2 2 Amidohydrolase HATPase_c PF02518.21 OAP60895.1 - 2.5e-24 85.1 0.0 4.5e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP60895.1 - 3e-19 69.0 0.2 9.1e-19 67.5 0.2 1.9 1 1 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 OAP60895.1 - 1e-16 61.1 0.0 3.2e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 OAP60895.1 - 1.1e-13 51.1 0.0 1.5e-06 28.2 0.0 3.0 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 OAP60895.1 - 1.4e-09 37.7 0.1 1.4e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 OAP60895.1 - 8.4e-06 25.9 0.0 2.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 OAP60895.1 - 2.7e-05 24.7 0.0 0.00022 21.7 0.0 2.6 3 0 0 3 3 3 1 GAF domain PAS_3 PF08447.6 OAP60895.1 - 4.4e-05 23.5 0.4 0.00052 20.0 0.3 2.6 1 1 0 1 1 1 1 PAS fold GAF PF01590.21 OAP60895.1 - 0.00016 21.8 0.0 0.00051 20.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain PAS PF00989.19 OAP60895.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 OAP60895.1 - 0.0012 18.5 0.0 0.004 16.9 0.0 1.9 1 0 0 1 1 1 1 PAS domain Toprim_N PF08275.6 OAP60895.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain Zn_clus PF00172.13 OAP60896.1 - 1.4e-07 31.2 4.5 3e-07 30.2 3.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Smac_DIABLO PF09057.5 OAP60896.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases PrsW-protease PF13367.1 OAP60897.1 - 1.4e-18 66.7 10.5 7.6e-18 64.3 7.3 2.0 1 1 0 1 1 1 1 Protease prsW family DUF2324 PF10086.4 OAP60897.1 - 0.0024 17.1 7.0 0.0048 16.1 2.4 2.9 2 1 1 3 3 3 1 Putative membrane peptidase family (DUF2324) DUF805 PF05656.9 OAP60897.1 - 0.55 10.0 5.7 2 8.2 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Rtt106 PF08512.7 OAP60898.1 - 6.1e-24 83.8 0.0 1e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF2890 PF11081.3 OAP60898.1 - 0.011 15.8 8.0 0.011 15.8 5.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) G-patch PF01585.18 OAP60899.1 - 8e-12 44.7 1.1 1.8e-11 43.5 0.8 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 OAP60899.1 - 7.7e-05 22.2 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP60899.1 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP60899.1 - 0.0052 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Med3 PF11593.3 OAP60899.1 - 0.44 9.7 4.7 0.61 9.2 3.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AMP-binding PF00501.23 OAP60900.1 - 8e-91 304.4 0.0 9.3e-91 304.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP60900.1 - 0.00021 22.1 0.7 0.0011 19.8 0.1 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 OAP60900.1 - 0.003 16.1 0.0 0.0079 14.7 0.0 1.6 2 0 0 2 2 2 1 GH3 auxin-responsive promoter YCII PF03795.9 OAP60901.1 - 7.6e-13 48.4 0.0 9.1e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF3680 PF12441.3 OAP60901.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) Sod_Cu PF00080.15 OAP60902.1 - 5.3e-17 62.2 0.5 1.5e-16 60.7 0.4 1.7 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Sld5 PF05916.6 OAP60903.1 - 4.6e-13 49.3 0.0 9.8e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 GINS complex protein zf-rbx1 PF12678.2 OAP60904.1 - 4.9e-06 26.5 5.3 4.9e-06 26.5 3.7 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 OAP60904.1 - 3.6e-05 23.4 12.3 0.00012 21.8 8.5 2.0 1 1 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 OAP60904.1 - 0.0028 17.4 4.2 0.0067 16.2 2.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 OAP60904.1 - 0.0057 16.5 10.0 0.014 15.3 3.6 2.4 1 1 0 2 2 2 1 FANCL C-terminal domain zf-Di19 PF05605.7 OAP60904.1 - 0.017 15.2 4.1 0.71 10.0 0.0 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HMG_box PF00505.14 OAP60905.1 - 6.5e-10 39.1 0.6 1.1e-09 38.4 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box DUF2981 PF11200.3 OAP60907.1 - 0.19 10.8 2.5 0.39 9.7 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SURF4 PF02077.10 OAP60908.1 - 8.8e-95 317.0 9.2 1e-94 316.8 6.4 1.0 1 0 0 1 1 1 1 SURF4 family DUF2929 PF11151.3 OAP60908.1 - 2.8 8.0 11.5 0.12 12.4 2.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) IU_nuc_hydro PF01156.14 OAP60909.1 - 8.5e-57 192.7 0.0 1.2e-45 156.0 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase GST_C PF00043.20 OAP60910.1 - 4.1e-07 29.8 0.0 6.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP60910.1 - 8.2e-07 29.4 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP60910.1 - 4.3e-06 26.8 0.0 7.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP60910.1 - 7.9e-05 22.4 9.0 0.00068 19.4 5.1 3.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ribonuc_L-PSP PF01042.16 OAP60911.1 - 7.3e-14 51.5 0.0 8.3e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HgmA PF04209.8 OAP60913.1 - 4.4e-122 407.5 0.0 5.6e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF3425 PF11905.3 OAP60914.1 - 2.2e-15 56.7 1.5 4.5e-15 55.7 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Omptin PF01278.15 OAP60914.1 - 0.11 11.5 0.3 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Omptin family SnoaL_2 PF12680.2 OAP60915.1 - 8.5e-08 32.5 1.0 1.1e-07 32.1 0.7 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 OAP60915.1 - 1.9e-06 28.0 0.3 2.7e-06 27.5 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.2 OAP60915.1 - 3.9e-05 24.1 0.0 0.00025 21.5 0.0 1.9 2 0 0 2 2 2 1 Putative lumazine-binding SnoaL_3 PF13474.1 OAP60915.1 - 6.9e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 OAP60915.1 - 0.00086 19.2 0.9 0.0012 18.7 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd PF12870.2 OAP60915.1 - 0.029 14.4 0.0 0.081 12.9 0.0 1.8 2 0 0 2 2 2 0 Lumazine-binding domain LEH PF07858.7 OAP60915.1 - 0.03 14.3 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain DUF1843 PF08898.5 OAP60915.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Aa_trans PF01490.13 OAP60916.1 - 3.8e-20 71.7 33.7 6.5e-20 70.9 23.4 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein NACHT PF05729.7 OAP60917.1 - 4.2e-08 33.0 0.0 3.2e-07 30.1 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP60917.1 - 3.7e-05 23.7 0.0 3.7e-05 23.7 0.0 3.9 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 OAP60917.1 - 0.00071 19.7 0.2 0.0083 16.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAP60917.1 - 0.0076 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 OAP60917.1 - 0.028 14.1 0.1 0.24 11.1 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 OAP60917.1 - 0.098 12.9 0.0 0.098 12.9 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 OAP60917.1 - 0.29 11.4 10.1 0.54 10.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 OAP60917.1 - 0.32 10.7 0.0 0.32 10.7 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF87 COesterase PF00135.23 OAP60918.1 - 1.2e-50 172.7 0.0 2.9e-50 171.5 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP60918.1 - 0.031 13.8 0.1 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Arginase PF00491.16 OAP60919.1 - 2.8e-72 243.3 0.2 3.6e-72 242.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family MatE PF01554.13 OAP60920.1 - 7.6e-40 136.1 30.1 7.6e-27 93.9 3.5 2.6 3 0 0 3 3 3 2 MatE Fungal_trans_2 PF11951.3 OAP60921.1 - 2.2e-38 131.8 0.9 2.8e-38 131.5 0.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.14 OAP60922.1 - 1.5e-29 102.9 0.0 2.1e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAP60922.1 - 0.032 12.5 0.0 0.052 11.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 OAP60922.1 - 0.045 13.6 0.1 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 B12 binding domain MFS_1 PF07690.11 OAP60923.1 - 9.7e-50 169.2 31.3 5.9e-49 166.6 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP60923.1 - 3.1e-12 45.8 13.3 3.1e-12 45.8 9.2 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAP60923.1 - 6.3e-09 34.5 1.0 1e-08 33.9 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 OAP60923.1 - 7.4 7.0 5.7 1.5 9.3 0.1 2.8 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_1_2 PF00155.16 OAP60924.1 - 6.7e-38 130.5 0.0 8.4e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAP60924.1 - 0.00054 18.3 0.0 0.00085 17.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 OAP60924.1 - 0.013 14.5 0.0 0.024 13.6 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 OAP60925.1 - 1.4e-15 56.9 17.9 2.1e-15 56.3 12.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.14 OAP60925.1 - 0.049 13.6 1.0 0.095 12.7 0.7 1.4 1 0 0 1 1 1 0 Cellulose binding domain DUF308 PF03729.8 OAP60925.1 - 0.4 10.6 5.3 1 9.4 2.8 2.5 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF2842 PF11003.3 OAP60925.1 - 2 8.3 8.3 0.14 12.0 0.2 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2842) NAD_binding_6 PF08030.7 OAP60926.1 - 6.7e-18 65.0 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAP60926.1 - 1.8e-16 60.3 17.0 1.8e-16 60.3 11.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 OAP60926.1 - 3.3e-11 42.9 0.0 8.2e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain DASH_Hsk3 PF08227.6 OAP60926.1 - 0.04 14.0 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Fasciclin PF02469.17 OAP60927.1 - 8.8e-32 109.8 0.0 1.2e-20 73.8 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain FTA2 PF13095.1 OAP60928.1 - 7.8e-25 87.6 0.0 1.4e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Fungal_trans PF04082.13 OAP60930.1 - 2.5e-09 36.4 0.1 4.8e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Serglycin PF04360.7 OAP60930.1 - 0.056 13.1 0.7 0.39 10.4 0.2 2.1 2 0 0 2 2 2 0 Serglycin SBP_bac_10 PF07596.6 OAP60931.1 - 0.043 13.8 8.7 0.054 13.5 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) GIDA_assoc_3 PF13932.1 OAP60932.1 - 0.09 12.8 0.1 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 GidA associated domain 3 PCI PF01399.22 OAP60933.1 - 2.5e-20 72.7 0.0 7.3e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 OAP60933.1 - 0.0015 17.8 1.2 0.37 10.0 0.0 2.5 2 1 0 2 2 2 2 Putative aspartate racemase ATP-sulfurylase PF01747.12 OAP60934.1 - 4.6e-86 287.5 0.1 6.6e-86 287.0 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 OAP60934.1 - 2.4e-54 183.2 0.0 3.7e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 OAP60934.1 - 1.3e-52 177.3 0.0 2e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 OAP60934.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.7 OAP60934.1 - 0.12 11.9 0.0 0.48 10.0 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PAPS_reduct PF01507.14 OAP60935.1 - 6.5e-46 156.3 0.1 1.1e-45 155.5 0.0 1.4 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Sin3_corepress PF08295.7 OAP60935.1 - 0.049 13.3 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Sin3 family co-repressor HAD PF12710.2 OAP60936.1 - 2.3e-14 53.9 0.0 3.2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP60936.1 - 8.9e-11 42.6 0.0 1.3e-09 38.7 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAP60936.1 - 2.8e-10 40.2 0.0 9.8e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 OAP60936.1 - 0.012 14.8 0.0 0.048 12.8 0.0 1.8 1 1 0 1 1 1 0 Putative Phosphatase DUF705 PF05152.7 OAP60936.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) HAD_2 PF13419.1 OAP60936.1 - 0.087 13.0 0.1 0.32 11.2 0.0 1.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SP_C-Propep PF08999.5 OAP60937.1 - 0.086 12.3 0.2 0.23 10.9 0.2 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide hEGF PF12661.2 OAP60937.1 - 0.16 12.1 1.7 0.33 11.1 1.2 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 OAP60937.1 - 0.19 11.9 12.4 0.34 11.1 8.6 1.4 1 0 0 1 1 1 0 EGF-like domain OppC_N PF12911.2 OAP60937.1 - 0.3 10.4 3.2 0.68 9.3 2.3 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Adeno_52K PF03052.10 OAP60938.1 - 0.011 14.9 0.3 0.47 9.6 0.0 2.2 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa ATP-synt_D PF01813.12 OAP60939.1 - 0.0042 16.6 0.0 0.022 14.2 0.0 1.9 2 0 0 2 2 2 1 ATP synthase subunit D Complex1_LYR_1 PF13232.1 OAP60940.1 - 5.2e-23 81.0 2.6 6.8e-23 80.6 1.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAP60940.1 - 2.3e-21 75.3 2.6 3.2e-21 74.8 1.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 OAP60940.1 - 0.013 15.9 3.2 0.023 15.1 2.2 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Gpi16 PF04113.9 OAP60940.1 - 0.044 11.8 0.1 0.047 11.7 0.1 1.0 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Ribonuclease_P PF00825.13 OAP60940.1 - 0.11 12.3 2.0 1.8 8.5 0.7 2.0 1 1 1 2 2 2 0 Ribonuclease P zf-C2H2 PF00096.21 OAP60941.1 - 0.82 10.1 4.5 1.4 9.4 3.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP60941.1 - 0.96 9.9 3.8 1.7 9.1 2.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1761 PF08570.5 OAP60942.1 - 3.9e-23 81.8 2.0 4.4e-23 81.6 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Methyltransf_16 PF10294.4 OAP60943.1 - 2.3e-48 163.9 0.0 3.3e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAP60943.1 - 0.0015 19.1 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP60943.1 - 0.061 12.6 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 OAP60943.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GrpE PF01025.14 OAP60944.1 - 0.0075 15.8 3.9 0.99 8.9 1.0 2.2 2 0 0 2 2 2 2 GrpE DUF2563 PF10817.3 OAP60944.1 - 0.081 13.3 0.5 0.4 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2563) Fib_alpha PF08702.5 OAP60944.1 - 0.4 10.8 3.7 1.6 8.8 0.7 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Aminotran_4 PF01063.14 OAP60945.1 - 2.1e-22 79.7 0.0 3.1e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Nse4-Nse3_bdg PF15412.1 OAP60945.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Glutaredoxin PF00462.19 OAP60946.1 - 2.1e-15 56.4 0.0 1.4e-14 53.8 0.0 2.3 3 0 0 3 3 3 1 Glutaredoxin Flavoprotein PF02441.14 OAP60947.1 - 8.1e-40 135.4 0.0 9.8e-40 135.2 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein UbiA PF01040.13 OAP60948.1 - 8.2e-32 110.4 14.5 1e-31 110.0 10.0 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.17 OAP60949.1 - 7e-10 39.1 0.6 1.2e-08 35.1 0.4 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 OAP60949.1 - 3.9e-07 30.1 5.2 3.9e-07 30.1 3.6 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 OAP60949.1 - 0.00082 18.8 0.2 0.004 16.6 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Nucleic_acid_bd PF13820.1 OAP60949.1 - 0.086 12.4 0.5 0.22 11.1 0.3 1.6 1 0 0 1 1 1 0 Putative nucleic acid-binding region DUF1279 PF06916.8 OAP60950.1 - 7e-29 99.9 0.0 1.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Coa1 PF08695.5 OAP60951.1 - 6.9e-37 125.5 0.1 1.1e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF777 PF05606.6 OAP60952.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) Ribosomal_L2_C PF03947.13 OAP60953.1 - 2.1e-44 150.4 1.2 4.4e-34 117.0 0.2 2.4 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 OAP60953.1 - 3.3e-27 94.2 0.7 6.4e-27 93.3 0.5 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Fungal_trans PF04082.13 OAP60954.1 - 2.6e-29 101.9 0.2 5.4e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.1 OAP60955.1 - 1.4e-08 34.5 1.7 1.4 8.8 0.0 5.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAP60955.1 - 6e-06 25.8 1.2 0.069 12.8 0.0 4.3 3 1 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 OAP60955.1 - 4.9e-05 22.9 1.5 2.2 8.4 0.0 5.8 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP60955.1 - 0.0044 16.6 6.0 1.9 8.4 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP60955.1 - 0.0064 17.1 3.6 13 6.5 0.7 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAP60955.1 - 0.37 10.8 4.7 47 4.0 1.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP60955.1 - 0.69 10.7 13.2 16 6.5 0.1 5.4 6 1 1 7 7 7 0 Tetratricopeptide repeat NmrA PF05368.8 OAP60956.1 - 1e-17 64.2 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP60956.1 - 7.4e-07 29.3 0.0 1.1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 OAP60956.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 OAP60956.1 - 0.022 13.7 0.1 0.22 10.4 0.0 2.2 1 1 1 2 2 2 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 OAP60956.1 - 0.037 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Mito_carr PF00153.22 OAP60957.1 - 8e-43 144.0 0.6 1.1e-15 57.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.16 OAP60958.1 - 1.3e-08 34.6 0.2 2.7e-07 30.3 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Neugrin PF06413.6 OAP60959.1 - 0.033 14.0 1.4 0.035 13.9 1.0 1.1 1 0 0 1 1 1 0 Neugrin zf-C2H2 PF00096.21 OAP60960.1 - 3.2e-07 30.2 19.6 0.00063 19.9 1.7 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP60960.1 - 1.3e-05 25.1 18.6 0.0019 18.4 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 OAP60960.1 - 0.00046 20.2 3.6 0.12 12.6 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 OAP60960.1 - 0.0026 17.8 0.2 0.005 16.9 0.2 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 OAP60960.1 - 0.0067 16.5 3.6 1.2 9.3 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 OAP60960.1 - 0.019 15.2 7.6 4.5 7.7 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 OAP60960.1 - 0.37 10.7 7.9 0.76 9.7 1.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3795 PF12675.2 OAP60960.1 - 1.3 9.2 6.7 1.5 9.0 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) PNK3P PF08645.6 OAP60962.1 - 4.2e-53 179.0 0.1 6.5e-53 178.4 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 OAP60962.1 - 5.7e-12 45.7 0.0 3.4e-11 43.2 0.0 2.3 3 1 0 3 3 3 1 AAA domain HAD_2 PF13419.1 OAP60962.1 - 2.9e-06 27.5 0.2 0.15 12.2 0.0 3.4 1 1 2 3 3 3 2 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.7 OAP60962.1 - 0.002 17.2 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.10 OAP60962.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 OAP60962.1 - 0.12 12.5 0.0 0.92 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2130 PF09903.4 OAP60962.1 - 0.41 9.3 2.0 7 5.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Med18 PF09637.5 OAP60963.1 - 1.2e-42 146.2 0.0 1.3e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 OAP60964.1 - 5.6e-33 114.3 3.9 1.4e-31 109.8 2.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) BTG PF07742.7 OAP60965.1 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 BTG family RGS PF00615.14 OAP60966.1 - 1.8e-11 44.1 0.0 2.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF647 PF04884.9 OAP60967.1 - 7.3e-82 274.3 0.4 1.1e-81 273.7 0.3 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PITH PF06201.8 OAP60970.1 - 6.6e-46 155.8 0.0 8.1e-46 155.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.16 OAP60971.1 - 7.5e-31 106.8 12.9 7.5e-31 106.8 9.0 1.8 1 1 1 2 2 2 1 Snf7 MR_MLE_N PF02746.11 OAP60971.1 - 0.0079 16.1 0.6 0.021 14.8 0.1 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Abhydrolase_5 PF12695.2 OAP60972.1 - 5.5e-11 42.4 0.1 9.1e-10 38.4 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP60972.1 - 1.1e-10 41.3 0.0 9.8e-08 31.6 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 OAP60972.1 - 1.2e-10 40.9 0.1 2.4e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Esterase_phd PF10503.4 OAP60972.1 - 2.3e-08 33.5 0.0 0.00017 20.9 0.0 3.3 2 1 1 3 3 3 2 Esterase PHB depolymerase DLH PF01738.13 OAP60972.1 - 5.5e-08 32.3 0.0 9.4e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 OAP60972.1 - 9.6e-08 32.1 0.9 0.00071 19.5 0.1 3.0 2 1 1 3 3 3 2 Alpha/beta hydrolase family Esterase PF00756.15 OAP60972.1 - 5.5e-07 29.2 0.0 0.00029 20.3 0.0 2.4 2 0 0 2 2 2 2 Putative esterase Zn_clus PF00172.13 OAP60973.1 - 8.7e-08 31.9 8.7 1.9e-07 30.8 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP60974.1 - 7.5e-43 146.5 46.8 7.5e-43 146.5 32.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP60974.1 - 1.4e-10 40.0 24.5 2.3e-10 39.2 17.0 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAP60974.1 - 1.2e-08 34.0 10.9 1.2e-08 34.0 7.5 4.1 4 0 0 4 4 4 3 Sugar (and other) transporter EMP24_GP25L PF01105.19 OAP60975.1 - 5.1e-39 133.8 0.1 6.2e-39 133.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Big_1 PF02369.11 OAP60975.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) p450 PF00067.17 OAP60976.1 - 1.3e-63 215.1 0.0 2e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 OAP60976.1 - 7.2e-12 44.5 4.2 1.5e-11 43.5 2.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Band_7 PF01145.20 OAP60976.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 SPFH domain / Band 7 family Sugar_tr PF00083.19 OAP60977.1 - 1.8e-83 280.6 25.4 2.2e-83 280.3 17.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60977.1 - 1.2e-15 57.0 46.1 4.7e-09 35.4 16.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mur_ligase PF01225.20 OAP60977.1 - 0.11 12.5 0.1 0.63 10.1 0.0 2.4 3 0 0 3 3 3 0 Mur ligase family, catalytic domain Sugar_tr PF00083.19 OAP60978.1 - 2.9e-120 401.8 21.1 3.3e-120 401.7 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP60978.1 - 2.6e-26 92.2 51.9 3.3e-24 85.2 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 OAP60978.1 - 0.0023 16.6 10.2 0.0061 15.3 7.1 1.7 1 0 0 1 1 1 1 PUCC protein PIRT PF15099.1 OAP60978.1 - 0.079 12.1 2.8 0.21 10.8 0.1 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Lipase_GDSL PF00657.17 OAP60980.1 - 1.2e-16 61.2 0.1 1.7e-16 60.8 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peptidase_M28 PF04389.12 OAP60982.1 - 6e-28 97.7 0.0 9.1e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 OAP60982.1 - 0.042 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF3767 PF12597.3 OAP60982.1 - 0.067 12.8 0.4 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) DUF443 PF04276.7 OAP60982.1 - 3.2 7.1 10.4 0.13 11.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF443) TraI_2 PF07514.6 OAP60983.1 - 0.087 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative helicase HSP70 PF00012.15 OAP60983.1 - 0.26 9.1 0.0 3.4 5.4 0.0 2.0 2 0 0 2 2 2 0 Hsp70 protein Rad10 PF03834.9 OAP60985.1 - 2.7e-31 107.0 0.1 4.3e-31 106.4 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 OAP60985.1 - 0.00013 22.0 0.4 0.00035 20.6 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 OAP60985.1 - 0.0011 18.5 0.1 0.0028 17.2 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 OAP60985.1 - 0.018 14.8 1.0 0.059 13.2 0.0 2.2 3 0 0 3 3 3 0 Helix-hairpin-helix motif RRM_1 PF00076.17 OAP60986.1 - 1.6e-41 139.7 0.1 7.2e-17 60.7 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP60986.1 - 9.6e-31 105.5 0.0 1.9e-15 56.5 0.0 4.8 5 0 0 5 5 5 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP60986.1 - 5.9e-17 61.2 0.1 6.4e-09 35.5 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.23 OAP60987.1 - 2.2e-11 43.3 0.0 3.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arginase PF00491.16 OAP60988.1 - 1.9e-75 253.7 0.7 2.5e-75 253.3 0.5 1.1 1 0 0 1 1 1 1 Arginase family AA_permease PF00324.16 OAP60989.1 - 3.5e-109 365.2 35.4 4.4e-109 364.9 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP60989.1 - 3e-18 65.5 38.4 4e-18 65.1 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 OAP60989.1 - 0.0015 18.3 3.4 0.0015 18.3 2.3 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF1772) Orthoreo_P10 PF07204.6 OAP60989.1 - 0.43 10.3 2.7 1.4 8.7 1.9 1.9 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Orai-1 PF07856.7 OAP60989.1 - 0.69 9.4 13.6 0.55 9.7 4.3 2.5 2 0 0 2 2 2 0 Mediator of CRAC channel activity DUF3602 PF12223.3 OAP60990.1 - 2.8e-15 56.4 9.9 5.1e-05 23.5 0.4 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 OAP60990.1 - 0.052 13.2 0.9 3.3 7.3 0.0 3.0 3 0 0 3 3 3 0 GTP1/OBG zf-C2H2 PF00096.21 OAP60991.1 - 0.023 14.9 3.2 0.078 13.3 2.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-BED PF02892.10 OAP60991.1 - 0.026 14.2 1.0 0.056 13.2 0.7 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.1 OAP60991.1 - 0.3 11.5 1.8 0.88 10.0 1.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Abhydrolase_6 PF12697.2 OAP60992.1 - 1e-21 77.8 0.1 1.3e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP60992.1 - 3.8e-09 36.4 0.0 9.6e-05 22.0 0.0 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP60992.1 - 2.9e-08 33.5 0.0 5.4e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP60992.1 - 0.0069 15.8 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.8 OAP60992.1 - 0.029 13.9 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.3 OAP60992.1 - 0.069 13.0 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Pam16 PF03656.8 OAP60993.1 - 3.4e-08 33.3 0.1 7.3e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.26 OAP60993.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.1 OAP60993.1 - 0.0032 16.7 0.5 0.0079 15.4 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3918) AA_permease_2 PF13520.1 OAP60995.1 - 3.5e-46 157.6 50.7 4.7e-46 157.1 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP60995.1 - 5.5e-22 77.7 45.3 7.1e-22 77.3 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease PetN PF03742.9 OAP60995.1 - 0.012 15.1 2.7 0.012 15.1 1.9 2.7 2 0 0 2 2 2 0 PetN Hemerythrin PF01814.18 OAP60996.1 - 4.2e-13 49.6 0.9 5.4e-13 49.2 0.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MARVEL PF01284.18 OAP60997.1 - 4.6e-07 29.7 9.6 8.9e-07 28.8 6.6 1.4 1 0 0 1 1 1 1 Membrane-associating domain ATG27 PF09451.5 OAP60997.1 - 0.49 9.5 0.0 0.49 9.5 0.0 1.7 2 0 0 2 2 2 0 Autophagy-related protein 27 TMEMspv1-c74-12 PF11044.3 OAP60997.1 - 5.9 6.5 5.2 0.68 9.5 0.5 1.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF3425 PF11905.3 OAP60998.1 - 7.4e-22 77.7 0.1 1.6e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.13 OAP60998.1 - 3.8e-09 36.2 6.5 6.6e-09 35.5 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L24e PF01246.15 OAP60999.1 - 7.4e-27 93.0 1.9 1.7e-26 91.8 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF2175 PF09943.4 OAP60999.1 - 1.5 8.9 4.7 2 8.5 0.3 2.4 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Sugar_tr PF00083.19 OAP61000.1 - 1.5e-76 257.8 20.5 1.7e-76 257.6 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61000.1 - 1.8e-12 46.6 29.2 1.8e-12 46.6 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP61000.1 - 2.7e-05 22.7 20.7 0.00069 18.1 1.5 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein DUF2574 PF10836.3 OAP61000.1 - 0.06 13.0 0.2 0.17 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Zn_clus PF00172.13 OAP61001.1 - 1.9e-05 24.5 9.3 1.9e-05 24.5 6.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP61001.1 - 0.0023 16.8 0.1 0.0036 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 OAP61002.1 - 1.7e-09 37.7 0.0 2.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 OAP61002.1 - 0.12 11.8 0.0 0.8 9.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.5 OAP61002.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 OAP61003.1 - 7.6e-08 32.5 0.0 9.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP61003.1 - 9.2e-05 21.4 0.0 0.012 14.5 0.0 2.7 2 1 1 3 3 3 1 Male sterility protein Semialdhyde_dh PF01118.19 OAP61003.1 - 0.0016 18.7 0.0 0.0053 17.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 OAP61003.1 - 0.002 16.8 0.0 0.0043 15.7 0.0 1.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAP61003.1 - 0.01 14.7 0.0 0.067 12.0 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 OAP61003.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 OAP61003.1 - 0.095 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 OAP61004.1 - 2.2e-09 36.3 2.4 3.2e-08 32.6 1.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 OAP61005.1 - 3.1e-25 89.4 0.5 3.8e-25 89.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP61005.1 - 5e-14 52.4 0.0 1e-13 51.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP61005.1 - 6.7e-09 35.6 0.0 4.3e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 OAP61005.1 - 0.045 12.6 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) PhyH PF05721.8 OAP61006.1 - 5e-23 82.2 0.1 6.3e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 OAP61006.1 - 0.0081 16.4 0.0 0.023 14.9 0.0 1.8 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Fer2_BFD PF04324.10 OAP61007.1 - 0.14 12.2 1.3 0.2 11.7 0.2 1.8 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain CDP-OH_P_transf PF01066.16 OAP61008.1 - 9.2e-15 54.7 8.2 9.2e-15 54.7 5.7 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Zn_Tnp_IS1595 PF12760.2 OAP61009.1 - 0.012 15.3 1.2 0.022 14.5 0.8 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 OAP61009.1 - 0.098 12.3 0.9 0.17 11.5 0.6 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PSCyt3 PF07627.6 OAP61009.1 - 0.14 12.0 1.0 0.28 11.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) Mito_fiss_reg PF05308.6 OAP61009.1 - 0.36 10.1 2.8 0.52 9.6 2.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_L13 PF00572.13 OAP61010.1 - 1e-27 96.7 0.0 2.6e-27 95.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L13 WD40 PF00400.27 OAP61011.1 - 1.9e-15 56.0 13.6 1.2e-06 28.1 0.5 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAP61011.1 - 1.8e-07 30.2 2.4 0.02 13.6 0.6 3.5 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_3 PF13570.1 OAP61011.1 - 0.005 17.0 0.4 7 7.0 0.0 4.1 4 1 1 5 5 5 1 PQQ-like domain DUF3312 PF11768.3 OAP61011.1 - 0.016 13.5 0.0 0.15 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) adh_short PF00106.20 OAP61012.1 - 6.5e-18 65.2 0.2 1e-17 64.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61012.1 - 1.3e-09 37.9 0.2 2.1e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Toprim_4 PF13662.1 OAP61012.1 - 0.023 14.6 0.1 5.7 7.0 0.0 2.5 1 1 1 2 2 2 0 Toprim domain YchF-GTPase_C PF06071.8 OAP61013.1 - 4.8e-34 115.9 0.3 1e-33 114.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 OAP61013.1 - 4.7e-12 45.8 0.0 1.1e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 OAP61013.1 - 0.00046 19.9 0.0 0.0016 18.2 0.0 1.9 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.13 OAP61013.1 - 0.00051 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 OAP61013.1 - 0.026 14.2 0.6 3.6 7.3 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SecA_PP_bind PF01043.15 OAP61013.1 - 0.027 14.8 0.1 0.072 13.4 0.1 1.8 1 1 0 1 1 1 0 SecA preprotein cross-linking domain AAA_23 PF13476.1 OAP61013.1 - 0.27 11.5 3.6 1.1 9.5 2.5 1.9 1 1 0 1 1 1 0 AAA domain Glyco_transf_15 PF01793.11 OAP61014.1 - 1.2e-115 385.9 1.8 1.6e-115 385.6 1.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Hira PF07569.6 OAP61015.1 - 4.6e-81 271.1 0.0 1.2e-80 269.8 0.0 1.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 OAP61015.1 - 1.5e-41 138.7 17.1 2.3e-07 30.4 0.0 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat HIRA_B PF09453.5 OAP61015.1 - 1.9e-08 33.5 0.1 5.6e-08 32.1 0.1 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 OAP61015.1 - 0.03 14.0 0.7 2.5 7.8 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 OAP61015.1 - 0.14 9.9 0.0 1.4 6.6 0.0 2.2 2 0 0 2 2 2 0 IKI3 family Band_7 PF01145.20 OAP61016.1 - 1.7e-30 106.2 1.2 3e-30 105.4 0.8 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 OAP61016.1 - 0.011 15.3 0.1 0.028 13.9 0.0 1.8 2 0 0 2 2 2 0 SPFH domain-Band 7 family ATP-cone PF03477.11 OAP61016.1 - 0.064 13.7 0.4 0.28 11.6 0.1 2.2 2 0 0 2 2 2 0 ATP cone domain Fungal_trans PF04082.13 OAP61017.1 - 1.2e-14 53.8 0.0 2.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Catalase PF00199.14 OAP61018.1 - 1e-146 488.5 0.7 2e-146 487.5 0.5 1.5 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAP61018.1 - 1e-11 44.5 0.3 2.5e-11 43.2 0.2 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Oxidored_molyb PF00174.14 OAP61019.1 - 8.4e-44 148.9 0.0 1.5e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 OAP61019.1 - 1.6e-23 82.7 3.9 2.9e-23 81.9 2.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.4 OAP61019.1 - 0.056 13.3 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 SLBB domain Cytochrom_B561 PF03188.11 OAP61020.1 - 0.00011 22.0 7.6 0.00011 22.0 5.2 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2306 PF10067.4 OAP61020.1 - 0.025 14.7 1.7 0.025 14.7 1.2 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2306) PRA1 PF03208.14 OAP61020.1 - 1.1 8.5 7.8 1.2 8.4 0.2 3.2 2 2 2 4 4 4 0 PRA1 family protein MFS_1 PF07690.11 OAP61021.1 - 2.2e-30 105.6 18.2 2.9e-30 105.1 11.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP61022.1 - 9.1e-07 28.0 0.0 1.7e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tautomerase_3 PF14832.1 OAP61023.1 - 4.8e-08 33.1 0.1 8.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme COesterase PF00135.23 OAP61024.1 - 6e-67 226.5 0.0 8.4e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP61024.1 - 5.3e-05 22.8 0.1 0.00098 18.7 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold ECM1 PF05782.6 OAP61024.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Pkinase PF00069.20 OAP61025.1 - 1.5e-38 132.4 0.0 1.9e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61025.1 - 8.6e-14 51.2 0.0 1.2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP61025.1 - 1.9e-05 24.5 0.0 0.0015 18.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family AhpC-TSA PF00578.16 OAP61026.1 - 1.3e-23 82.9 0.0 2.3e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAP61026.1 - 6.6e-14 51.6 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 OAP61026.1 - 0.0039 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Sedlin_N PF04628.8 OAP61027.1 - 1.6e-26 92.6 0.0 1.9e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Oxidored_q6 PF01058.17 OAP61028.1 - 3.3e-22 78.4 0.0 5.5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HMA PF00403.21 OAP61030.1 - 2.6e-17 62.7 2.0 3e-17 62.5 1.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1280 PF06918.9 OAP61030.1 - 0.12 11.5 0.4 0.13 11.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) DUF2293 PF10056.4 OAP61031.1 - 8.7e-26 89.7 0.1 2.7e-25 88.1 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Abhydrolase_6 PF12697.2 OAP61032.1 - 6.1e-17 62.2 0.1 6.5e-17 62.1 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP61032.1 - 6.2e-10 39.0 0.1 1.5e-08 34.4 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP61032.1 - 1.1e-09 38.2 0.0 3e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 OAP61032.1 - 7.3e-05 23.0 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 OAP61032.1 - 0.00012 21.7 0.0 0.001 18.7 0.0 1.9 1 1 1 2 2 2 1 Serine hydrolase Abhydrolase_2 PF02230.11 OAP61032.1 - 0.00095 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 OAP61032.1 - 0.0012 18.3 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Acyl_transf_1 PF00698.16 OAP61032.1 - 0.0027 17.1 0.1 0.0032 16.8 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain PGAP1 PF07819.8 OAP61032.1 - 0.0051 16.4 0.3 0.0093 15.5 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.8 OAP61032.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TauD PF02668.11 OAP61033.1 - 1.7e-33 116.3 0.1 3.1e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.13 OAP61034.1 - 5.6e-06 26.1 10.4 9.3e-06 25.4 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 OAP61035.1 - 5.8e-35 121.2 0.0 9.1e-35 120.5 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.1 OAP61036.1 - 2.9e-26 92.2 0.0 4.9e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP61036.1 - 6.9e-22 77.6 0.0 1.3e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 OAP61037.1 - 2.4e-26 91.8 0.0 2.5e-15 56.5 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP61037.1 - 4e-22 77.7 0.7 9.2e-09 35.2 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP61037.1 - 1.1e-21 76.7 0.1 1.5e-07 31.6 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 OAP61037.1 - 8.1e-19 66.4 0.2 4.8e-05 22.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 OAP61037.1 - 1.7e-13 49.3 0.0 0.0029 17.6 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat F-box PF00646.28 OAP61037.1 - 5.3e-05 22.7 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP61037.1 - 0.00037 20.1 0.1 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF1353 PF07087.6 OAP61037.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) HNH_2 PF13391.1 OAP61038.1 - 1.8e-08 34.0 0.0 4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Complex1_LYR PF05347.10 OAP61039.1 - 8.7e-08 31.8 4.7 1.5e-07 31.0 3.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAP61039.1 - 0.0016 18.6 5.0 0.0016 18.6 3.5 1.8 1 1 0 1 1 1 1 Complex1_LYR-like YjcZ PF13990.1 OAP61039.1 - 0.074 12.1 0.1 0.09 11.8 0.1 1.1 1 0 0 1 1 1 0 YjcZ-like protein Complex1_LYR_2 PF13233.1 OAP61039.1 - 1.4 9.4 4.1 4.7 7.7 2.8 1.9 1 1 0 1 1 1 0 Complex1_LYR-like MFS_1 PF07690.11 OAP61040.1 - 1.1e-41 142.7 44.8 1.1e-41 142.7 31.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP61040.1 - 1.8e-07 30.1 12.4 1.8e-07 30.1 8.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1446 PF07287.6 OAP61041.1 - 2.7e-136 453.7 0.1 3.3e-136 453.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) CoA_transf_3 PF02515.12 OAP61042.1 - 1.9e-29 102.2 0.0 7.1e-28 97.1 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III bZIP_C PF12498.3 OAP61043.1 - 6.6 8.0 8.5 0.93 10.7 1.8 2.1 2 0 0 2 2 2 0 Basic leucine-zipper C terminal HSP20 PF00011.16 OAP61044.1 - 7e-20 70.8 1.4 1.6e-14 53.5 0.1 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family Cys_rich_CWC PF14375.1 OAP61045.1 - 0.095 12.6 3.9 1.7 8.6 0.1 2.7 3 0 0 3 3 3 0 Cysteine-rich CWC Troponin-I_N PF11636.3 OAP61045.1 - 5.9 6.6 7.4 2 8.1 0.3 2.6 2 0 0 2 2 2 0 Troponin I residues 1-32 HSP20 PF00011.16 OAP61046.1 - 1.2e-08 34.7 0.0 1.1e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Hsp20/alpha crystallin family HLH PF00010.21 OAP61047.1 - 4.6e-08 32.6 0.0 1.3e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3918 PF13056.1 OAP61048.1 - 0.22 10.8 2.7 0.13 11.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) HNH_2 PF13391.1 OAP61049.1 - 0.0011 18.6 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease T4SS PF07996.6 OAP61049.1 - 0.095 12.5 1.0 0.14 11.9 0.7 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins Nop14 PF04147.7 OAP61050.1 - 3.2 5.5 8.1 3.6 5.3 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family Acetyltransf_3 PF13302.1 OAP61051.1 - 2.8e-21 76.1 0.0 7.6e-21 74.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP61051.1 - 1.5e-06 28.0 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 OAP61051.1 - 0.0001 22.2 0.1 0.00017 21.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP61051.1 - 0.004 17.1 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAP61051.1 - 0.029 14.5 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ion_trans PF00520.26 OAP61053.1 - 2.9e-07 29.9 2.9 5.3e-07 29.0 2.0 1.4 1 0 0 1 1 1 1 Ion transport protein DUF904 PF06005.7 OAP61053.1 - 0.0009 19.4 0.5 0.0015 18.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF2216 PF10226.4 OAP61053.1 - 0.012 15.1 0.1 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) Med21 PF11221.3 OAP61053.1 - 0.044 13.7 1.6 0.075 13.0 1.1 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Myosin_tail_1 PF01576.14 OAP61053.1 - 0.045 11.4 0.8 0.059 11.0 0.5 1.0 1 0 0 1 1 1 0 Myosin tail V-ATPase_H_C PF11698.3 OAP61053.1 - 0.091 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H MLANA PF14991.1 OAP61054.1 - 1.1 9.2 6.7 0.29 11.1 2.1 1.8 1 1 1 2 2 2 0 Protein melan-A HpcH_HpaI PF03328.9 OAP61055.1 - 5.9e-34 116.8 0.0 7.7e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 OAP61055.1 - 0.037 12.8 0.2 0.091 11.6 0.2 1.6 2 1 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain PK PF00224.16 OAP61055.1 - 0.068 11.7 0.2 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Aminotran_3 PF00202.16 OAP61056.1 - 4.5e-100 334.7 0.0 5.6e-100 334.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 OAP61056.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Spt4 PF06093.8 OAP61057.1 - 2e-32 110.8 0.2 2.4e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Metallophos PF00149.23 OAP61058.1 - 1.4e-38 132.3 0.1 2.1e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 OAP61058.1 - 3.2e-30 103.9 1.2 1.2e-29 102.1 0.8 2.0 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 OAP61058.1 - 1.4e-16 59.8 11.0 8.9e-15 54.1 3.1 2.6 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 OAP61058.1 - 3.1e-09 36.0 9.1 0.00059 19.3 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP61058.1 - 5.6e-08 32.1 7.9 0.0077 16.0 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAP61058.1 - 0.00042 20.7 0.9 0.71 10.6 0.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAP61058.1 - 0.0023 18.5 5.5 0.88 10.3 0.5 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP61058.1 - 0.016 15.5 2.8 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAP61058.1 - 0.039 13.8 0.3 0.22 11.3 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP61058.1 - 0.056 13.9 0.8 7.9 7.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAP61058.1 - 0.061 13.5 3.8 1.7 9.0 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 OAP61058.1 - 3 7.7 9.0 9.1 6.2 0.4 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain F-box PF00646.28 OAP61059.1 - 0.0027 17.3 0.0 0.0083 15.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF3669 PF12417.3 OAP61061.1 - 3.2e-19 68.4 0.1 7.3e-19 67.2 0.1 1.6 1 0 0 1 1 1 1 Zinc finger protein AMP-binding PF00501.23 OAP61062.1 - 4.2e-77 259.3 0.0 5.5e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP61062.1 - 1.2e-09 38.9 1.0 7.3e-09 36.4 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CMD PF02627.15 OAP61063.1 - 0.00012 21.7 2.0 0.11 12.4 0.1 2.6 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Pep3_Vps18 PF05131.9 OAP61064.1 - 1.9e-45 153.8 0.0 1.8e-44 150.7 0.0 2.4 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 OAP61064.1 - 3.5e-10 39.6 8.9 1.6e-06 27.7 0.1 3.5 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.4 OAP61064.1 - 0.00059 19.9 0.1 0.0013 18.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 OAP61064.1 - 0.0017 18.1 4.1 0.0045 16.8 2.8 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAP61064.1 - 0.0026 17.4 0.5 0.0066 16.1 0.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAP61064.1 - 0.024 14.2 0.3 0.061 12.9 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 OAP61064.1 - 0.05 13.6 0.0 0.21 11.6 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF1664 PF07889.7 OAP61064.1 - 0.082 12.7 1.6 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C3HC4_2 PF13923.1 OAP61064.1 - 0.084 12.9 0.7 0.22 11.5 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.1 OAP61064.1 - 0.094 13.0 4.0 0.26 11.6 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 OAP61064.1 - 0.1 12.7 0.1 0.54 10.4 0.1 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger PspA_IM30 PF04012.7 OAP61064.1 - 0.23 10.7 4.2 0.22 10.8 0.1 2.6 3 0 0 3 3 3 0 PspA/IM30 family TPR_21 PF09976.4 OAP61064.1 - 0.54 10.1 7.4 0.043 13.7 0.5 2.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 OAP61065.1 - 1.4e-30 106.2 35.9 1.4e-30 106.2 24.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Spo12 PF05032.7 OAP61066.1 - 0.00012 21.6 0.1 0.0004 19.9 0.1 2.0 1 0 0 1 1 1 1 Spo12 family KdpD PF02702.12 OAP61066.1 - 0.008 15.3 0.0 0.0097 15.0 0.0 1.0 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain PQ-loop PF04193.9 OAP61067.1 - 5.4e-40 134.7 9.8 3.9e-21 74.3 1.0 2.6 2 0 0 2 2 2 2 PQ loop repeat RskA PF10099.4 OAP61067.1 - 0.011 15.5 0.1 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3784 PF12650.2 OAP61067.1 - 2.9 7.9 6.3 0.31 11.0 0.1 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) FA_desaturase PF00487.19 OAP61067.1 - 3.1 7.1 12.5 0.028 13.8 0.9 2.8 2 1 1 3 3 3 0 Fatty acid desaturase Zn_clus PF00172.13 OAP61069.1 - 9.7e-07 28.6 8.6 3.3e-06 26.9 6.0 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP61069.1 - 0.093 11.3 10.9 3.7 6.0 7.6 2.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain PUF PF00806.14 OAP61070.1 - 1.3e-58 191.2 18.0 1.7e-09 36.6 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Toxin_38 PF14866.1 OAP61070.1 - 0.38 10.8 1.1 5.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Potassium channel toxin Mcp5_PH PF12814.2 OAP61072.1 - 2.8e-43 146.7 0.1 5.7e-43 145.7 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology CCDC155 PF14662.1 OAP61072.1 - 6.6 6.2 39.5 0.0079 15.8 16.8 3.2 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 CLTH PF10607.4 OAP61073.1 - 1e-27 96.6 0.1 2.8e-27 95.2 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 OAP61073.1 - 5e-05 22.9 0.0 0.00014 21.5 0.0 1.8 1 0 0 1 1 1 1 LisH Glt_symporter PF03616.9 OAP61074.1 - 0.015 13.8 0.6 0.025 13.0 0.4 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter MARVEL PF01284.18 OAP61074.1 - 5.2 6.8 16.7 12 5.7 11.4 1.6 1 1 0 1 1 1 0 Membrane-associating domain RDD PF06271.7 OAP61074.1 - 9 6.1 11.3 1.4 8.8 1.5 2.2 2 0 0 2 2 2 0 RDD family PhyH PF05721.8 OAP61075.1 - 8.3e-07 29.2 0.2 2.2e-06 27.8 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.3 OAP61076.1 - 0.076 11.5 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain SSF PF00474.12 OAP61079.1 - 1.2e-21 76.8 28.3 1.9e-21 76.1 19.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family SSB PF00436.20 OAP61081.1 - 1.1e-14 54.1 0.0 1.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 OAP61082.1 - 1.2e-74 250.9 10.5 1.4e-74 250.7 7.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor Got1 PF04178.7 OAP61082.1 - 1.2 9.2 7.4 0.34 11.0 0.9 2.6 2 0 0 2 2 2 0 Got1/Sft2-like family Vip3A_N PF12495.3 OAP61083.1 - 0.022 14.4 0.2 0.046 13.3 0.1 1.5 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal OmpH PF03938.9 OAP61083.1 - 0.043 13.7 0.4 0.083 12.8 0.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 OAP61083.1 - 0.07 12.7 1.3 0.13 11.8 0.9 1.3 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 OAP61083.1 - 0.14 10.7 1.7 0.2 10.2 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GSH_synth_ATP PF03917.12 OAP61084.1 - 3.4e-100 335.2 0.0 1.9e-99 332.7 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 OAP61084.1 - 2.1e-29 101.6 0.0 3.6e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 OAP61085.1 - 2.8e-47 160.9 0.1 6.2e-47 159.8 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP61085.1 - 1.9e-14 53.2 0.0 5.9e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAM_2 PF07647.12 OAP61085.1 - 8.4e-06 25.5 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2305 PF10230.4 OAP61086.1 - 1.8e-46 158.7 0.0 5.9e-36 124.2 0.0 3.0 2 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 OAP61086.1 - 0.00054 19.7 1.1 0.012 15.3 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP61086.1 - 0.02 14.4 0.8 0.02 14.4 0.5 2.1 3 0 0 3 3 3 0 PGAP1-like protein Thioesterase PF00975.15 OAP61086.1 - 0.055 13.6 3.0 0.056 13.6 0.3 2.2 1 1 1 2 2 2 0 Thioesterase domain DUF2660 PF10859.3 OAP61086.1 - 0.17 12.1 1.0 0.33 11.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Peptidase_S49_N PF08496.5 OAP61086.1 - 0.21 11.3 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Abhydrolase_6 PF12697.2 OAP61086.1 - 1.5 8.6 11.7 0.058 13.2 2.6 2.5 2 2 0 2 2 2 0 Alpha/beta hydrolase family Suf PF05843.9 OAP61086.1 - 1.7 8.2 5.8 3.1 7.4 4.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DCP1 PF06058.8 OAP61087.1 - 1.3e-14 54.2 0.0 1.9e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Septin PF00735.13 OAP61088.1 - 5.6e-106 353.6 0.1 1.4e-105 352.4 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 OAP61088.1 - 0.00022 21.1 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAP61088.1 - 0.00057 19.7 3.7 0.66 9.7 0.0 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 OAP61088.1 - 0.0031 16.6 0.1 0.0079 15.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAP61088.1 - 0.0046 16.4 0.0 0.11 11.8 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAP61088.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 OAP61088.1 - 0.052 14.0 0.1 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein GBP_C PF02841.9 OAP61088.1 - 0.14 11.3 6.1 0.21 10.7 4.3 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF3653 PF12375.3 OAP61088.1 - 0.2 11.8 2.0 4 7.7 0.7 2.7 2 0 0 2 2 2 0 Phage protein FtsK_SpoIIIE PF01580.13 OAP61088.1 - 0.23 10.9 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 OAP61088.1 - 0.24 12.2 5.4 0.41 11.4 0.1 2.9 2 2 0 2 2 2 0 AAA domain TPD52 PF04201.10 OAP61088.1 - 1.3 8.6 6.0 2.2 7.9 4.2 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Pkinase PF00069.20 OAP61089.1 - 1.1e-57 195.1 0.0 1.4e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61089.1 - 2.9e-28 98.6 0.0 7e-28 97.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP61089.1 - 0.034 13.0 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 OAP61089.1 - 0.15 11.4 0.2 0.36 10.1 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Y_phosphatase3 PF13350.1 OAP61090.1 - 1.5e-34 119.6 0.0 3.8e-34 118.3 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 OAP61090.1 - 3.7e-09 36.5 0.1 1.3e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 OAP61090.1 - 0.0021 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 OAP61090.1 - 0.0035 16.7 0.0 0.0049 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 OAP61090.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate IucA_IucC PF04183.7 OAP61090.1 - 0.091 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 IucA / IucC family DLIC PF05783.6 OAP61091.1 - 3.9e-31 108.2 5.1 2.1e-29 102.5 0.0 3.1 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) Utp12 PF04003.7 OAP61091.1 - 0.05 13.5 0.6 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Dip2/Utp12 Family RRM_1 PF00076.17 OAP61092.1 - 2.9e-15 55.6 0.1 6.4e-15 54.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP61092.1 - 1.2e-09 37.9 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP61092.1 - 0.00029 20.6 0.0 0.00052 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2992 PF11208.3 OAP61092.1 - 6.9 6.5 12.8 13 5.6 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) AMP-binding PF00501.23 OAP61093.1 - 2.9e-93 312.5 0.0 3.4e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP61093.1 - 1.2e-16 61.3 0.1 3.2e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2052 PF09747.4 OAP61095.1 - 8e-36 123.6 7.3 8e-36 123.6 5.1 3.1 3 1 0 3 3 3 1 Coiled-coil domain containing protein (DUF2052) ThiF PF00899.16 OAP61096.1 - 1.7e-18 66.7 0.1 3.3e-18 65.8 0.0 1.5 2 0 0 2 2 2 1 ThiF family Init_tRNA_PT PF04179.7 OAP61097.1 - 1.1e-122 410.1 0.0 9e-87 291.7 0.0 2.2 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase Aldo_ket_red PF00248.16 OAP61098.1 - 3e-51 173.9 0.0 3.6e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.6 OAP61098.1 - 0.091 12.1 0.4 17 4.8 0.1 2.6 2 0 0 2 2 2 0 Poliovirus 3A protein like ALMT PF11744.3 OAP61098.1 - 0.092 11.3 0.1 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Pro_CA PF00484.14 OAP61099.1 - 3.3e-15 56.4 0.0 5.1e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase DrrA_P4M PF14860.1 OAP61100.1 - 0.019 14.6 0.0 0.42 10.3 0.0 2.5 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain PLA2_B PF01735.13 OAP61102.1 - 3.2e-15 55.2 0.2 3.4e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Zn_clus PF00172.13 OAP61103.1 - 0.00048 19.9 12.9 0.00093 19.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2250 PF10007.4 OAP61103.1 - 0.053 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Fungal_trans PF04082.13 OAP61103.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cauli_DNA-bind PF03310.8 OAP61104.1 - 0.12 12.2 0.1 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein vATP-synt_E PF01991.13 OAP61105.1 - 3.4e-61 206.0 12.5 3.9e-61 205.7 8.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Mg_trans_NIPA PF05653.9 OAP61106.1 - 3e-14 52.6 8.5 8.7e-09 34.7 0.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 OAP61106.1 - 1.7 8.7 24.0 0.042 13.8 3.3 3.3 3 1 0 3 3 3 0 EamA-like transporter family DUF4619 PF15398.1 OAP61107.1 - 0.017 14.5 0.9 0.034 13.5 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) Ribosom_S12_S23 PF00164.20 OAP61108.1 - 1.8e-40 137.1 0.5 2.1e-40 136.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CTP_transf_2 PF01467.21 OAP61109.1 - 2.3e-22 79.7 0.0 4e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase PP2C PF00481.16 OAP61110.1 - 4.9e-80 268.6 0.1 9.7e-80 267.6 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 OAP61110.1 - 0.00011 21.6 0.3 0.00028 20.3 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C He_PIG PF05345.7 OAP61111.1 - 6.4e-11 42.0 7.8 0.0022 17.9 0.1 4.9 4 0 0 4 4 4 3 Putative Ig domain Peptidase_M7 PF02031.11 OAP61111.1 - 0.061 13.0 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family SUR7 PF06687.7 OAP61112.1 - 3.6e-37 128.0 6.6 4.2e-37 127.7 4.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 OAP61112.1 - 0.0011 18.7 5.0 0.0011 18.7 3.5 1.9 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF202 PF02656.10 OAP61112.1 - 0.16 12.1 9.8 8.2 6.7 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Fig1 PF12351.3 OAP61112.1 - 1.3 8.8 17.5 0.016 15.1 6.9 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Mannitol_dh_C PF08125.8 OAP61113.1 - 2.6e-51 174.1 0.0 3.8e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 OAP61113.1 - 3.1e-21 75.8 0.6 1.8e-20 73.4 0.1 2.3 2 1 1 3 3 3 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 OAP61113.1 - 0.00025 20.7 1.5 0.0067 16.0 0.0 3.0 4 0 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 OAP61113.1 - 0.0027 17.4 0.5 0.041 13.6 0.1 2.8 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 OAP61113.1 - 0.019 14.4 0.0 0.47 9.8 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 OAP61113.1 - 0.022 14.1 1.2 0.027 13.8 0.2 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 OAP61113.1 - 0.05 13.6 0.4 0.96 9.4 0.0 2.6 3 0 0 3 3 3 0 NADH(P)-binding Methyltransf_23 PF13489.1 OAP61113.1 - 0.068 12.8 0.0 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF3425 PF11905.3 OAP61114.1 - 1.9e-19 69.9 0.1 3.6e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 OAP61115.1 - 3.1e-15 56.5 1.4 1.4e-14 54.3 0.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61115.1 - 6.1e-06 26.0 0.4 1.3e-05 24.8 0.3 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP61115.1 - 0.00026 20.8 0.0 0.0005 19.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 OAP61115.1 - 0.098 11.8 0.2 0.32 10.2 0.1 1.9 1 1 0 1 1 1 0 NmrA-like family ECH PF00378.15 OAP61116.1 - 8.2e-44 149.5 0.0 1.1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PGPGW PF09656.5 OAP61116.1 - 0.023 13.9 0.1 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) SRF-TF PF00319.13 OAP61117.1 - 1.4e-23 81.8 0.2 1.9e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) adh_short PF00106.20 OAP61118.1 - 3.7e-06 26.9 0.0 3.6e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Tetraspannin PF00335.15 OAP61119.1 - 3.9e-12 45.9 10.0 4.8e-12 45.6 6.9 1.1 1 0 0 1 1 1 1 Tetraspanin family Ferric_reduct PF01794.14 OAP61119.1 - 0.12 12.4 3.5 0.069 13.2 0.9 1.6 2 0 0 2 2 2 0 Ferric reductase like transmembrane component Fungal_trans_2 PF11951.3 OAP61120.1 - 8.9e-07 27.8 2.9 1.2e-06 27.4 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61120.1 - 0.013 15.3 2.1 0.029 14.2 1.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DbpA PF03880.10 OAP61121.1 - 0.0046 16.5 0.0 0.0097 15.5 0.0 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_5 PF13893.1 OAP61121.1 - 0.0057 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_Tnp_1_4 PF13701.1 OAP61121.1 - 0.38 8.8 3.5 0.21 9.7 1.0 1.5 2 0 0 2 2 2 0 Transposase DDE domain group 1 Peptidase_S49_N PF08496.5 OAP61122.1 - 0.0098 15.6 4.5 0.0098 15.6 3.1 2.0 2 0 0 2 2 2 1 Peptidase family S49 N-terminal RNA_polI_A34 PF08208.6 OAP61122.1 - 5.4 6.6 17.3 3.2 7.3 5.7 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 CENP-F_N PF10481.4 OAP61123.1 - 0.0044 16.4 11.1 0.0064 15.9 7.7 1.2 1 0 0 1 1 1 1 Cenp-F N-terminal domain IncA PF04156.9 OAP61123.1 - 0.0089 15.6 1.4 0.7 9.4 0.8 2.2 2 0 0 2 2 2 1 IncA protein HALZ PF02183.13 OAP61123.1 - 0.012 15.3 3.8 0.4 10.4 1.6 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2046 PF09755.4 OAP61123.1 - 0.029 13.2 4.3 0.17 10.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) PV-1 PF06637.6 OAP61123.1 - 0.19 10.2 8.7 0.028 12.9 3.0 1.8 2 0 0 2 2 2 0 PV-1 protein (PLVAP) Macoilin PF09726.4 OAP61123.1 - 0.27 9.4 20.7 0.39 8.9 14.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1640 PF07798.6 OAP61123.1 - 0.32 11.0 5.1 0.19 11.7 0.7 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) DUF4140 PF13600.1 OAP61123.1 - 0.37 11.2 10.3 0.046 14.1 1.7 2.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 OAP61123.1 - 0.59 9.6 10.9 0.39 10.2 4.8 2.1 2 0 0 2 2 2 0 Septum formation initiator GreA_GreB_N PF03449.10 OAP61123.1 - 0.72 9.9 9.1 0.096 12.7 3.0 1.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal FlaC_arch PF05377.6 OAP61123.1 - 0.79 9.6 3.1 1.9 8.4 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DegS PF05384.6 OAP61123.1 - 0.97 8.6 9.6 0.053 12.7 1.9 2.2 3 0 0 3 3 3 0 Sensor protein DegS SlyX PF04102.7 OAP61123.1 - 2.4 8.5 7.3 8.3 6.8 1.7 2.6 2 0 0 2 2 2 0 SlyX LCD1 PF09798.4 OAP61123.1 - 6.9 4.5 6.9 3.3 5.5 0.6 2.0 2 0 0 2 2 2 0 DNA damage checkpoint protein DivIVA PF05103.8 OAP61123.1 - 7.8 6.5 10.5 0.25 11.3 1.6 2.4 3 0 0 3 3 3 0 DivIVA protein DUF972 PF06156.8 OAP61123.1 - 8.5 6.7 6.2 5.7 7.3 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CAML PF14963.1 OAP61124.1 - 0.0092 15.3 2.5 0.2 10.9 0.6 2.2 2 0 0 2 2 2 2 Calcium signal-modulating cyclophilin ligand RapA_C PF12137.3 OAP61124.1 - 0.018 13.8 1.2 0.094 11.5 0.9 1.7 1 1 1 2 2 2 0 RNA polymerase recycling family C-terminal MRP-L46 PF11788.3 OAP61124.1 - 0.13 12.9 0.7 0.19 12.4 0.5 1.3 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 DUF1444 PF07285.6 OAP61124.1 - 0.21 10.9 1.3 0.28 10.4 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) YtxH PF12732.2 OAP61124.1 - 6.3 7.2 13.4 2.3 8.6 4.7 2.8 2 1 0 2 2 2 0 YtxH-like protein Beta-lactamase PF00144.19 OAP61125.1 - 0.025 13.5 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase Beta-lactamase PF00144.19 OAP61126.1 - 1.3e-05 24.4 0.0 1.3e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Rgp1 PF08737.5 OAP61127.1 - 0.019 14.0 0.0 0.078 12.0 0.0 1.8 2 0 0 2 2 2 0 Rgp1 Arrestin_N PF00339.24 OAP61127.1 - 0.023 14.5 0.0 0.065 13.0 0.0 1.8 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain SH3_2 PF07653.12 OAP61128.1 - 1.7e-13 49.8 0.0 2.9e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 OAP61128.1 - 4.2e-13 48.4 0.2 1.3e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain G-alpha PF00503.15 OAP61128.1 - 5.1e-13 48.4 0.0 1.2e-12 47.3 0.0 1.5 2 0 0 2 2 2 1 G-protein alpha subunit SH3_9 PF14604.1 OAP61128.1 - 2.9e-12 45.9 0.0 1.1e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain FlaC_arch PF05377.6 OAP61128.1 - 0.16 11.8 0.3 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HisKA_3 PF07730.8 OAP61128.1 - 0.82 10.0 3.6 1.1 9.6 0.7 2.3 2 0 0 2 2 2 0 Histidine kinase DUF3176 PF11374.3 OAP61129.1 - 1.4e-36 124.7 0.2 3.6e-36 123.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF4131 PF13567.1 OAP61129.1 - 0.68 9.3 4.4 0.93 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AMP-binding PF00501.23 OAP61130.1 - 5.2e-70 235.9 0.1 6.7e-70 235.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP61130.1 - 7.8e-16 58.7 0.1 3.2e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_L17 PF01196.14 OAP61131.1 - 1.9e-27 95.6 0.0 3e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 IF-2B PF01008.12 OAP61132.1 - 5e-44 150.3 0.0 4.2e-23 81.7 0.0 2.1 1 1 1 2 2 2 2 Initiation factor 2 subunit family NIF PF03031.13 OAP61133.1 - 1.2e-53 181.0 0.0 1.9e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EamA PF00892.15 OAP61134.1 - 3.9e-14 52.7 22.7 5e-08 33.0 5.7 3.5 3 1 0 3 3 3 3 EamA-like transporter family SUZ PF12752.2 OAP61135.1 - 1.6e-14 54.1 0.6 1.6e-14 54.1 0.4 5.3 5 0 0 5 5 5 1 SUZ domain R3H PF01424.17 OAP61135.1 - 2e-07 30.5 0.0 5.4e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 R3H domain cwf18 PF08315.7 OAP61136.1 - 9.6e-41 139.2 3.1 9.6e-41 139.2 2.2 2.0 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF3811 PF11656.3 OAP61136.1 - 1.1 9.4 7.3 0.63 10.1 2.9 2.2 2 1 0 2 2 2 0 YjbD family (DUF3811) PPR_2 PF13041.1 OAP61137.1 - 4.9e-09 36.0 0.0 0.013 15.4 0.0 4.1 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 OAP61137.1 - 6.6e-07 29.1 0.2 0.51 10.7 0.0 5.6 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 OAP61137.1 - 1.2e-05 24.9 2.8 0.12 12.3 0.0 4.7 4 1 0 4 4 4 2 PPR repeat UPF0547 PF10571.4 OAP61138.1 - 0.15 11.8 0.2 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 TFIID-18kDa PF02269.11 OAP61139.1 - 3e-17 62.1 0.0 7e-16 57.8 0.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit MitMem_reg PF13012.1 OAP61140.1 - 1.3e-18 67.1 0.2 2e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 OAP61140.1 - 2.8e-15 56.0 0.0 4.8e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BTB PF00651.26 OAP61141.1 - 1.5e-24 86.0 0.0 7e-12 45.3 0.1 3.1 4 0 0 4 4 4 2 BTB/POZ domain Ank PF00023.25 OAP61141.1 - 1.1e-12 47.0 0.4 2.4e-06 27.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 OAP61141.1 - 9.3e-12 45.1 0.0 2.4e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP61141.1 - 5.2e-09 36.0 0.1 1.5e-07 31.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP61141.1 - 9.9e-09 35.4 0.1 3e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP61141.1 - 9.3e-07 28.5 0.2 0.0038 17.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat DEAD PF00270.24 OAP61142.1 - 8.9e-35 119.6 0.0 1.4e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP61142.1 - 6.9e-24 83.5 0.0 4.3e-23 80.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP61142.1 - 9e-06 25.6 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 OAP61142.1 - 0.0029 16.7 0.0 0.027 13.5 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF2365 PF10157.4 OAP61143.1 - 3.1e-05 23.9 0.1 3.8e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) MAP65_ASE1 PF03999.7 OAP61143.1 - 0.00049 18.8 0.3 0.00076 18.2 0.2 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Poty_PP PF08440.5 OAP61143.1 - 0.0031 16.6 0.6 0.0041 16.2 0.4 1.1 1 0 0 1 1 1 1 Potyviridae polyprotein Syntaxin-6_N PF09177.6 OAP61143.1 - 0.0034 17.7 1.8 2.5 8.5 0.4 2.3 1 1 1 2 2 2 2 Syntaxin 6, N-terminal BLOC1_2 PF10046.4 OAP61143.1 - 0.0062 16.6 1.8 0.05 13.7 0.6 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 OAP61143.1 - 0.0065 16.4 1.7 0.011 15.6 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) DivIVA PF05103.8 OAP61143.1 - 0.0068 16.4 0.7 0.012 15.6 0.5 1.5 1 0 0 1 1 1 1 DivIVA protein Mnd1 PF03962.10 OAP61143.1 - 0.0069 16.0 0.4 0.0095 15.6 0.3 1.2 1 0 0 1 1 1 1 Mnd1 family Syntaxin PF00804.20 OAP61143.1 - 0.0092 16.1 5.1 0.1 12.7 0.5 2.7 1 1 2 3 3 3 1 Syntaxin DUF1664 PF07889.7 OAP61143.1 - 0.01 15.6 1.2 0.016 14.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.8 OAP61143.1 - 0.015 16.0 0.7 0.22 12.2 0.6 2.2 1 1 0 1 1 1 0 Occludin homology domain EzrA PF06160.7 OAP61143.1 - 0.015 13.5 0.1 0.02 13.0 0.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APG17 PF04108.7 OAP61143.1 - 0.02 13.7 0.3 0.028 13.2 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 GAS PF13851.1 OAP61143.1 - 0.021 14.0 0.3 0.27 10.4 0.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GAT PF03127.9 OAP61143.1 - 0.033 14.1 0.0 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 GAT domain Vps53_N PF04100.7 OAP61143.1 - 0.043 12.6 1.0 0.063 12.0 0.7 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal Perilipin PF03036.11 OAP61143.1 - 0.045 12.5 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Perilipin family Spc7 PF08317.6 OAP61143.1 - 0.048 12.3 0.6 0.071 11.7 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin_2 PF14523.1 OAP61143.1 - 0.051 13.6 0.8 0.44 10.5 0.2 2.2 1 1 1 2 2 2 0 Syntaxin-like protein DUF4570 PF15134.1 OAP61143.1 - 0.056 13.2 1.9 1.8 8.4 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Med3 PF11593.3 OAP61143.1 - 0.057 12.6 0.4 0.091 11.9 0.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TBPIP PF07106.8 OAP61143.1 - 0.057 12.9 1.9 2.8 7.4 1.0 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 OAP61143.1 - 0.083 12.7 0.1 0.4 10.4 0.1 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 OAP61143.1 - 0.085 12.8 3.7 1.7 8.7 2.5 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fzo_mitofusin PF04799.8 OAP61143.1 - 0.095 12.0 1.7 0.21 10.9 1.2 1.7 1 1 0 1 1 1 0 fzo-like conserved region Prefoldin PF02996.12 OAP61143.1 - 0.1 12.2 0.3 1 9.0 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit BAR_2 PF10455.4 OAP61143.1 - 0.12 11.2 1.1 0.2 10.5 0.8 1.4 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking CorA PF01544.13 OAP61143.1 - 0.12 11.3 3.9 1 8.3 2.9 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4164 PF13747.1 OAP61143.1 - 0.15 12.2 5.9 2.4 8.3 4.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) CK2S PF15011.1 OAP61143.1 - 0.15 11.8 0.5 1.3 8.7 0.1 2.2 1 1 1 2 2 2 0 Casein Kinase 2 substrate Tropomyosin_1 PF12718.2 OAP61143.1 - 0.21 11.4 2.0 1 9.1 1.5 1.9 1 1 0 1 1 1 0 Tropomyosin like DUF1515 PF07439.6 OAP61143.1 - 0.21 11.4 3.2 0.29 10.9 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Sipho_Gp157 PF05565.6 OAP61143.1 - 0.24 10.9 4.1 0.5 9.9 2.8 1.6 1 1 0 1 1 1 0 Siphovirus Gp157 Vps51 PF08700.6 OAP61143.1 - 0.31 10.9 2.6 4.6 7.1 0.7 2.8 2 1 0 2 2 2 0 Vps51/Vps67 DUF883 PF05957.8 OAP61143.1 - 0.35 11.2 2.8 5.3 7.5 0.0 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) FlaC_arch PF05377.6 OAP61143.1 - 0.49 10.3 3.5 0.58 10.1 0.6 2.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) zf-C4H2 PF10146.4 OAP61143.1 - 0.53 10.2 3.8 1.9 8.4 2.7 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein Atg14 PF10186.4 OAP61143.1 - 1 8.2 4.0 0.86 8.4 2.0 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 OAP61143.1 - 2.6 8.4 11.4 0.39 11.0 2.6 2.8 2 1 0 2 2 2 0 Snapin/Pallidin Rabaptin PF03528.10 OAP61143.1 - 3.5 7.5 7.3 0.24 11.3 0.8 2.0 2 1 0 2 2 2 0 Rabaptin CtIP_N PF10482.4 OAP61143.1 - 9.4 6.0 7.6 0.89 9.3 1.4 2.1 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Wbp11 PF09429.5 OAP61144.1 - 1.1e-21 76.5 16.5 1.1e-21 76.5 11.5 2.2 3 1 0 3 3 3 1 WW domain binding protein 11 DUF3040 PF11239.3 OAP61144.1 - 0.78 9.8 4.9 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Pkinase PF00069.20 OAP61145.1 - 3e-59 200.2 0.0 4.4e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61145.1 - 1.5e-35 122.5 0.0 1.8e-25 89.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAP61145.1 - 0.0017 17.3 0.0 0.0081 15.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pol_alpha_B_N PF08418.5 OAP61145.1 - 0.0046 16.5 14.2 0.055 12.9 3.6 2.3 2 0 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal NCA2 PF08637.5 OAP61145.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 APH PF01636.18 OAP61145.1 - 0.054 13.2 0.4 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.21 OAP61146.1 - 5e-09 35.9 13.5 2.9e-05 24.1 1.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP61146.1 - 8e-07 29.0 1.1 8e-07 29.0 0.8 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP61146.1 - 0.00034 20.7 9.7 0.086 13.2 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAP61146.1 - 0.00069 19.6 3.9 0.18 12.0 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP61146.1 - 0.0038 17.3 1.4 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 OAP61146.1 - 0.075 12.9 3.1 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 OAP61146.1 - 2 8.2 10.3 2.6 7.8 0.4 2.4 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 OAP61146.1 - 4.7 7.6 8.7 0.14 12.4 0.5 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DDRGK PF09756.4 OAP61147.1 - 0.31 10.4 2.3 0.53 9.6 0.0 2.1 2 1 0 2 2 2 0 DDRGK domain RNA_pol_3_Rpc31 PF11705.3 OAP61148.1 - 2.2 8.1 11.6 2.8 7.8 8.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2058 PF09831.4 OAP61148.1 - 2.8 7.7 10.9 3.7 7.4 7.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Sugar_tr PF00083.19 OAP61149.1 - 2.3e-75 253.8 29.0 2.7e-75 253.6 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61149.1 - 4.1e-26 91.5 32.8 1e-24 86.9 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP61149.1 - 4.7e-06 25.2 3.7 4.7e-06 25.2 2.5 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein PhyH PF05721.8 OAP61150.1 - 1.2e-16 61.4 0.1 1.5e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 OAP61150.1 - 0.007 16.8 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 OAP61150.1 - 0.034 14.4 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PPP4R2 PF09184.6 OAP61151.1 - 2 7.8 11.7 2.4 7.6 8.1 1.2 1 0 0 1 1 1 0 PPP4R2 BTV_NS2 PF04514.7 OAP61151.1 - 6.1 5.6 10.7 7.9 5.2 7.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FCP1_C PF09309.5 OAP61151.1 - 8.1 5.6 15.3 11 5.2 10.6 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Pkinase PF00069.20 OAP61152.1 - 7.9e-34 116.9 0.0 1.2e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61152.1 - 6.8e-16 58.1 0.0 9.5e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Chromo PF00385.19 OAP61152.1 - 0.027 14.1 0.1 0.066 12.9 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain APH PF01636.18 OAP61152.1 - 0.028 14.1 0.1 0.15 11.7 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family CorA PF01544.13 OAP61154.1 - 4.7e-17 61.9 0.0 1.1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CK2S PF15011.1 OAP61154.1 - 0.00038 20.2 1.0 0.26 11.0 0.2 2.8 3 0 0 3 3 3 2 Casein Kinase 2 substrate DUF1253 PF06862.7 OAP61155.1 - 5.1e-146 486.5 0.0 7.4e-146 486.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) FAM75 PF14650.1 OAP61155.1 - 0.17 11.2 3.3 0.29 10.4 2.3 1.3 1 0 0 1 1 1 0 FAM75 family Hydrolase_6 PF13344.1 OAP61156.1 - 8.8e-23 80.1 0.0 1.8e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP61156.1 - 5.2e-16 58.1 0.0 5.1e-15 54.9 0.0 2.6 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 OAP61156.1 - 0.012 16.0 0.0 3.8 7.8 0.0 2.7 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAP61156.1 - 0.016 15.4 0.1 3.1 7.9 0.0 3.1 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3665 PF12427.3 OAP61156.1 - 0.11 11.8 0.3 0.28 10.5 0.2 1.7 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Alpha-amylase PF00128.19 OAP61157.1 - 1.7e-18 67.0 1.7 1.3e-17 64.2 1.2 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 OAP61157.1 - 6e-14 52.1 0.0 1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 OAP61157.1 - 5.7e-07 29.1 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAP61157.1 - 5.8e-07 29.7 0.0 2e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 OAP61157.1 - 0.12 12.9 2.4 0.66 10.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain SMI1_KNR4 PF09346.5 OAP61158.1 - 1.1e-36 125.7 0.0 1.6e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DUF3321 PF11968.3 OAP61159.1 - 7.5e-69 231.7 0.0 1.6e-67 227.3 0.0 2.4 2 1 0 2 2 2 1 Putative methyltransferase (DUF3321) Kin17_mid PF10357.4 OAP61160.1 - 2.1e-51 172.8 1.0 3.8e-51 172.0 0.7 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 OAP61160.1 - 0.00012 22.0 1.4 0.00026 21.0 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP61160.1 - 0.0012 19.0 2.1 0.0022 18.1 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAP61160.1 - 0.0037 17.3 2.6 0.013 15.5 0.1 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Phage_min_cap2 PF06152.6 OAP61160.1 - 0.1 11.5 3.0 0.2 10.5 2.1 1.4 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF2263 PF10021.4 OAP61161.1 - 3.6e-09 36.7 0.0 7.4e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DIOX_N PF14226.1 OAP61162.1 - 5.7e-18 65.5 0.1 1.1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP61162.1 - 1e-10 41.8 0.0 1.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 OAP61162.1 - 0.08 12.4 0.0 0.57 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) CorA PF01544.13 OAP61163.1 - 1.9e-48 164.9 0.0 3e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein YmdB PF13277.1 OAP61163.1 - 0.048 12.6 0.3 0.077 12.0 0.2 1.2 1 0 0 1 1 1 0 YmdB-like protein ELMO_CED12 PF04727.8 OAP61163.1 - 0.3 10.6 1.1 0.42 10.1 0.1 1.6 2 0 0 2 2 2 0 ELMO/CED-12 family zf-rbx1 PF12678.2 OAP61164.1 - 8.6e-36 121.9 13.2 1.1e-35 121.5 9.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAP61164.1 - 3.5e-17 62.0 10.0 4.7e-17 61.6 7.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 OAP61164.1 - 3.1e-07 30.1 12.2 1.5e-06 27.8 8.5 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAP61164.1 - 0.0013 18.2 11.5 0.019 14.5 8.0 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP61164.1 - 0.0033 17.0 9.3 0.25 11.0 6.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP61164.1 - 0.065 13.2 13.0 1.5 8.9 9.1 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 OAP61164.1 - 0.1 12.5 8.5 0.43 10.5 6.0 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 OAP61164.1 - 0.6 10.1 9.6 1.4 8.9 6.7 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 OAP61164.1 - 0.96 9.2 7.0 0.95 9.2 1.5 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 OAP61164.1 - 1.1 9.0 11.6 8.7 6.1 8.0 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 OAP61164.1 - 2.1 8.5 10.8 49 4.1 7.5 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain PNRC PF15365.1 OAP61165.1 - 2.8e-05 24.0 8.9 2.8e-05 24.0 6.2 3.8 3 0 0 3 3 3 2 Proline-rich nuclear receptor coactivator G10 PF01125.12 OAP61166.1 - 2.9e-62 208.5 1.2 3.3e-62 208.3 0.9 1.0 1 0 0 1 1 1 1 G10 protein zf-Tim10_DDP PF02953.10 OAP61167.1 - 1.7e-21 75.2 2.1 2.1e-21 74.9 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pepsin-I3 PF06394.8 OAP61167.1 - 0.0037 16.8 0.5 0.0049 16.4 0.4 1.2 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain Pas_Saposin PF09016.5 OAP61167.1 - 0.041 13.8 0.1 0.071 13.1 0.0 1.4 1 1 0 1 1 1 0 Pas factor saposin fold GlutR_dimer PF00745.15 OAP61167.1 - 0.047 13.6 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF842 PF05811.8 OAP61167.1 - 0.052 13.0 2.5 0.086 12.3 1.7 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Ribosomal_L23eN PF03939.8 OAP61168.1 - 1.4e-21 76.2 10.5 1.4e-21 76.2 7.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 OAP61168.1 - 6.3e-17 61.3 1.7 1.3e-16 60.2 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 P2 PF07194.6 OAP61168.1 - 0.0042 16.8 0.3 0.0084 15.9 0.2 1.4 1 0 0 1 1 1 1 P2 response regulator binding domain SRPRB PF09439.5 OAP61168.1 - 0.037 13.2 0.1 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PHA-1 PF06542.6 OAP61168.1 - 0.043 12.5 0.6 0.056 12.1 0.4 1.1 1 0 0 1 1 1 0 Regulator protein PHA-1 DUF1323 PF07037.6 OAP61168.1 - 0.063 13.4 0.2 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) Thioredoxin PF00085.15 OAP61169.1 - 8.4e-05 22.2 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin UAA PF08449.6 OAP61170.1 - 6.2e-10 38.4 18.7 8.6e-10 38.0 13.0 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 OAP61170.1 - 4.5e-09 36.1 7.5 4.5e-09 36.1 5.2 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family Peptidase_A24 PF01478.13 OAP61170.1 - 1.1 9.3 16.5 0.1 12.7 0.3 3.8 2 2 1 3 3 3 0 Type IV leader peptidase family KH_1 PF00013.24 OAP61171.1 - 4.9e-08 32.4 0.0 1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 OAP61171.1 - 3.5e-05 23.3 0.1 0.00016 21.2 0.1 2.2 1 0 0 1 1 1 1 KH domain DUF2431 PF10354.4 OAP61172.1 - 7.7e-45 152.8 0.0 4.9e-33 114.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) WD40 PF00400.27 OAP61173.1 - 5.9e-13 48.1 15.8 1.1e-05 25.0 0.3 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 OAP61173.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain FAD_binding_3 PF01494.14 OAP61174.1 - 2.8e-36 125.3 0.0 6.7e-36 124.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 OAP61174.1 - 4.7e-14 51.8 1.2 5.8e-14 51.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Tenui_PVC2 PF06656.6 OAP61174.1 - 0.25 9.0 0.1 0.6 7.8 0.0 1.5 2 0 0 2 2 2 0 Tenuivirus PVC2 protein Thi4 PF01946.12 OAP61174.1 - 0.33 10.0 0.0 0.68 8.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family UQ_con PF00179.21 OAP61175.1 - 4.7e-48 162.1 0.0 5.2e-48 162.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP61175.1 - 0.00024 20.8 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 OAP61175.1 - 0.012 15.3 0.1 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 OAP61175.1 - 0.035 13.9 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain Ribosomal_L24e PF01246.15 OAP61177.1 - 2.5e-29 100.9 0.4 2.5e-29 100.9 0.3 2.2 2 1 1 3 3 3 1 Ribosomal protein L24e PVL_ORF50 PF07768.6 OAP61177.1 - 1.7 8.6 8.2 2.7 8.0 5.7 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family DUF1770 PF08589.5 OAP61178.1 - 1.2e-15 57.9 5.5 1.4e-14 54.5 3.8 2.1 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) FAP PF07174.6 OAP61178.1 - 6.5 5.9 12.7 8.9 5.5 8.8 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PfkB PF00294.19 OAP61179.1 - 1.3e-63 214.9 0.0 1.5e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 OAP61179.1 - 0.0032 16.7 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 OAP61180.1 - 2.1e-43 148.5 0.3 2.1e-43 148.5 0.2 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 OAP61180.1 - 2.2e-19 69.7 0.6 6.3e-19 68.2 0.4 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 OAP61180.1 - 2.7e-05 23.7 0.3 5.8e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.1 OAP61180.1 - 0.0094 16.0 0.3 0.06 13.5 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP61180.1 - 0.024 15.2 0.0 0.14 12.8 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP61180.1 - 0.029 13.9 0.5 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP61180.1 - 0.59 10.8 4.1 0.59 10.8 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L5_C PF00673.16 OAP61181.1 - 2.3e-24 84.9 0.0 3.3e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Beta-lactamase PF00144.19 OAP61182.1 - 2.6e-46 158.1 0.0 8.1e-46 156.5 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 OAP61182.1 - 0.045 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase UCH_1 PF13423.1 OAP61183.1 - 3.3e-68 230.2 0.0 2.2e-67 227.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NDUFA12 PF05071.11 OAP61184.1 - 5e-27 94.4 1.0 6.5e-27 94.0 0.7 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WHIM2 PF15613.1 OAP61184.1 - 0.033 14.1 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 LTV PF04180.9 OAP61185.1 - 4e-73 247.3 6.7 5e-73 247.0 4.6 1.1 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 OAP61186.1 - 2.3e-18 66.2 0.3 2.2e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP61186.1 - 1.9e-07 30.4 0.2 2.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 OAP61186.1 - 3.5e-05 23.0 0.0 7.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 OAP61186.1 - 9.1e-05 22.3 2.2 0.015 15.1 0.0 3.5 4 0 0 4 4 4 1 Dynamin family AIG1 PF04548.11 OAP61186.1 - 0.0074 15.4 0.1 0.0074 15.4 0.1 2.2 3 0 0 3 3 3 1 AIG1 family Med17 PF10156.4 OAP61186.1 - 0.0081 14.4 4.8 0.015 13.5 3.3 1.4 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Miro PF08477.8 OAP61186.1 - 0.047 14.1 0.0 0.18 12.2 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 OAP61186.1 - 0.17 11.2 1.2 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MFS_1 PF07690.11 OAP61187.1 - 2.5e-38 131.7 50.1 4.7e-38 130.7 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 OAP61187.1 - 0.006 14.6 1.2 0.006 14.6 0.8 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family SIT PF15330.1 OAP61188.1 - 0.017 15.2 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TadE PF07811.7 OAP61188.1 - 0.076 12.9 0.9 0.11 12.4 0.6 1.1 1 0 0 1 1 1 0 TadE-like protein zf-met PF12874.2 OAP61189.1 - 2.1e-08 34.0 2.9 0.00061 19.8 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAP61189.1 - 3.9e-08 33.2 3.5 0.0044 17.1 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 OAP61189.1 - 1e-05 25.4 15.8 0.012 15.8 0.4 4.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAP61189.1 - 1.5e-05 24.6 11.0 0.00011 21.9 0.2 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 OAP61189.1 - 0.0011 19.0 3.7 0.26 11.3 0.4 2.6 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 OAP61189.1 - 0.0067 16.7 17.0 0.013 15.8 0.2 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 OAP61189.1 - 0.019 14.5 8.5 0.3 10.8 0.5 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-AN1 PF01428.11 OAP61189.1 - 0.25 11.2 9.3 0.92 9.4 0.6 3.1 3 0 0 3 3 3 0 AN1-like Zinc finger zf-H2C2_2 PF13465.1 OAP61189.1 - 0.43 10.9 0.1 0.43 10.9 0.0 3.6 5 0 0 5 5 5 0 Zinc-finger double domain zf-LYAR PF08790.6 OAP61189.1 - 1.4 8.6 0.1 1.4 8.6 0.0 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger C1_1 PF00130.17 OAP61189.1 - 4.9 6.9 9.8 1.3 8.7 1.0 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.16 OAP61190.1 - 2.9e-11 43.0 41.8 9.9e-07 28.5 5.8 3.7 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 OAP61190.1 - 0.00024 20.8 9.1 0.00024 20.8 6.3 4.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP61190.1 - 0.0011 18.9 10.5 0.0011 18.9 7.3 4.9 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 OAP61190.1 - 0.0097 15.5 0.0 2.3 7.9 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.14 OAP61190.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain DNA_topoisoIV PF00521.15 OAP61190.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Abhydrolase_3 PF07859.8 OAP61191.1 - 1.4e-53 181.6 0.0 1.7e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP61191.1 - 2.4e-05 24.1 0.0 3.6e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP61191.1 - 3.3e-05 23.1 0.0 0.002 17.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 OAP61191.1 - 0.00017 20.4 1.3 0.0017 17.1 0.9 2.0 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 OAP61191.1 - 0.12 10.9 0.0 0.27 9.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) DUF1899 PF08953.6 OAP61191.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Sad1_UNC PF07738.8 OAP61192.1 - 3.3e-35 120.8 0.1 6.1e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PLDc_2 PF13091.1 OAP61194.1 - 8.6e-12 44.9 0.0 4.1e-06 26.5 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 OAP61194.1 - 5.8e-06 25.9 0.1 0.35 10.7 0.0 3.5 3 0 0 3 3 3 3 Phospholipase D Active site motif Pkinase PF00069.20 OAP61195.1 - 3.6e-54 183.6 0.0 5.2e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61195.1 - 3.5e-29 101.6 0.0 5e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP61195.1 - 5.3e-15 55.1 0.0 2.4e-11 43.1 0.0 3.1 2 1 1 3 3 3 3 Kinase-like Kdo PF06293.9 OAP61195.1 - 0.012 14.6 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl-CoA_dh_1 PF00441.19 OAP61196.1 - 2.5e-27 95.8 0.8 2.5e-27 95.8 0.5 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAP61196.1 - 5e-14 52.8 0.0 1.1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAP61196.1 - 5.6e-13 49.2 0.6 1e-12 48.4 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP61196.1 - 8.7e-13 47.5 0.0 1.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SAC3_GANP PF03399.11 OAP61197.1 - 3e-44 151.0 0.0 4.9e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2841 PF11001.3 OAP61198.1 - 1.3e-29 102.6 1.7 2.3e-29 101.8 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.18 OAP61199.1 - 5.2e-73 245.8 31.4 7.4e-41 140.3 4.8 3.2 4 0 0 4 4 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAP61199.1 - 2.2e-51 173.7 0.3 3e-30 105.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 OAP61199.1 - 2.3e-10 40.0 7.1 0.00085 18.6 0.1 4.7 3 2 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP61199.1 - 1.8e-06 28.1 0.1 0.085 12.7 0.0 4.2 3 1 1 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 OAP61199.1 - 5.3e-06 26.3 0.3 0.12 12.3 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 OAP61199.1 - 1e-05 25.5 1.1 0.19 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 OAP61199.1 - 1.2e-05 25.7 0.1 0.00086 19.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAP61199.1 - 2.4e-05 23.7 2.8 0.025 14.1 0.0 3.6 4 0 0 4 4 4 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAP61199.1 - 6.6e-05 22.1 0.4 0.026 13.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAP61199.1 - 0.0001 21.7 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 OAP61199.1 - 0.00012 22.5 0.1 0.53 10.7 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 OAP61199.1 - 0.0011 18.8 0.5 0.17 11.6 0.0 2.7 2 0 0 2 2 2 1 Dynamin family RNA_helicase PF00910.17 OAP61199.1 - 0.008 16.3 0.0 0.48 10.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.12 OAP61199.1 - 0.013 15.3 1.1 1 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 GTP_EFTU PF00009.22 OAP61199.1 - 0.028 13.8 0.1 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 OAP61199.1 - 0.049 13.1 0.1 5.2 6.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 OAP61199.1 - 0.05 13.1 3.1 6.3 6.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 OAP61199.1 - 0.06 12.4 0.2 3.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 OAP61199.1 - 0.076 13.1 3.3 3.5 7.7 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 OAP61199.1 - 0.16 12.7 0.1 15 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 OAP61199.1 - 0.87 8.9 4.9 6.5 6.0 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain Peptidase_C2 PF00648.16 OAP61200.1 - 4.8e-61 206.3 6.1 3.9e-40 137.7 1.5 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Herpes_capsid PF06112.6 OAP61200.1 - 0.17 11.9 3.9 0.42 10.6 2.7 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RabGAP-TBC PF00566.13 OAP61201.1 - 1.7e-47 161.6 0.0 2.9e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 OAP61201.1 - 0.0019 17.9 2.4 0.091 12.7 0.2 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 OAP61201.1 - 0.037 13.3 0.1 0.37 10.2 0.3 2.6 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.1 OAP61201.1 - 0.055 12.8 1.5 0.23 10.8 1.0 2.2 1 0 0 1 1 1 0 EF hand CNH PF00780.17 OAP61202.1 - 1e-68 231.7 0.0 1.5e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 OAP61202.1 - 4.2e-29 101.7 0.0 1e-28 100.4 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 OAP61202.1 - 7.2e-14 51.8 0.0 8.8e-12 45.1 0.0 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAP61202.1 - 8.4e-06 25.9 0.0 3.1e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 PH domain FAD_binding_3 PF01494.14 OAP61204.1 - 3.5e-49 167.7 0.0 4.9e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP61204.1 - 1e-05 24.6 0.0 0.033 13.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP61204.1 - 3.2e-05 23.8 0.3 0.00011 22.1 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP61204.1 - 0.00061 19.9 0.3 0.0055 16.7 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP61204.1 - 0.00069 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 OAP61204.1 - 0.00088 17.8 0.0 0.0095 14.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 OAP61204.1 - 0.0012 19.2 0.0 0.019 15.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP61204.1 - 0.0012 17.7 0.6 0.062 12.2 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.2 OAP61204.1 - 0.005 15.9 0.0 0.013 14.5 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP61204.1 - 0.01 14.7 0.4 0.056 12.2 0.3 1.8 1 1 1 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 OAP61204.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP61204.1 - 0.059 13.1 0.8 0.56 9.9 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding ApbA PF02558.11 OAP61204.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 OAP61205.1 - 1.3e-42 145.8 37.2 5.7e-36 123.9 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP61205.1 - 3.3e-12 45.5 0.0 1.7e-05 23.4 0.5 3.7 2 2 2 4 4 4 3 MFS/sugar transport protein Sugar_tr PF00083.19 OAP61205.1 - 5.2e-11 41.7 11.6 8.4e-10 37.8 0.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 OAP61205.1 - 0.00086 19.0 1.5 0.0088 15.8 0.1 2.9 2 0 0 2 2 2 1 MFS_1 like family Folate_carrier PF01770.13 OAP61205.1 - 0.017 13.6 0.0 0.027 12.9 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier 5_nucleotid_C PF02872.13 OAP61207.1 - 9.6e-33 113.3 0.0 1.6e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 OAP61207.1 - 6e-06 25.8 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP61207.1 - 0.00018 21.3 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_1_2 PF00155.16 OAP61208.1 - 1.7e-84 283.8 0.0 2.3e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAP61208.1 - 1.6e-07 30.4 0.0 2.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAP61208.1 - 2.9e-06 25.8 0.0 4.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 OAP61208.1 - 9.9e-06 24.8 0.2 2.7e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 OAP61208.1 - 0.0082 15.3 0.1 0.017 14.2 0.1 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3405 PF11885.3 OAP61208.1 - 0.0082 14.4 0.2 0.012 13.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DsrH PF04077.7 OAP61208.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 DsrH like protein RNA_pol_I_A49 PF06870.7 OAP61209.1 - 4.2e-46 157.2 0.0 6.2e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor OxoDH_E1alpha_N PF12573.3 OAP61209.1 - 0.036 13.6 0.1 0.092 12.3 0.1 1.7 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Haem_oxygenas_2 PF14518.1 OAP61211.1 - 1.6e-11 44.2 0.1 6.2e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Iron-containing redox enzyme 2OG-FeII_Oxy PF03171.15 OAP61212.1 - 4.3e-11 42.9 0.0 8.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP61212.1 - 1.1e-07 32.3 0.0 1.8e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal tRNA-synt_1b PF00579.20 OAP61214.1 - 2.7e-32 112.0 0.0 4.6e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ub-Mut7C PF14451.1 OAP61214.1 - 0.1 12.1 0.0 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Mut7-C ubiquitin Pyridox_ox_2 PF12900.2 OAP61215.1 - 2.8e-39 134.2 0.0 3.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M20 PF01546.23 OAP61216.1 - 2.2e-16 59.9 0.1 3.3e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAP61216.1 - 2.6e-13 49.6 0.0 6.4e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.20 OAP61217.1 - 1.3e-59 201.4 0.0 8.5e-54 182.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61217.1 - 2.5e-24 85.7 0.0 1.7e-21 76.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 OAP61217.1 - 2.2e-10 40.4 0.0 5.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 OAP61217.1 - 1e-06 27.9 0.0 1.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 OAP61217.1 - 0.021 14.1 0.2 0.057 12.7 0.2 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL AA_permease_2 PF13520.1 OAP61218.1 - 1.3e-53 182.0 52.3 1.7e-53 181.7 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP61218.1 - 5.8e-23 80.9 44.4 8.1e-23 80.5 30.8 1.2 1 0 0 1 1 1 1 Amino acid permease SNF2_N PF00176.18 OAP61219.1 - 7.2e-72 241.7 2.9 1.1e-71 241.1 2.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP61219.1 - 1.3e-16 60.1 0.0 3.4e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP61219.1 - 4.8e-06 26.5 0.1 1.7e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAP61219.1 - 0.00028 20.4 0.0 0.00083 18.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.1 OAP61220.1 - 5.5e-52 175.5 20.4 5.5e-52 175.5 14.2 3.2 3 0 0 3 3 3 1 DNA-binding domain Rotamase_3 PF13616.1 OAP61221.1 - 1.9e-16 60.3 0.1 2.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 OAP61221.1 - 2.9e-16 59.9 0.8 3.7e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 OAP61221.1 - 0.00041 20.9 0.0 0.00052 20.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Abhydrolase_6 PF12697.2 OAP61224.1 - 3.9e-26 92.3 0.0 9.2e-26 91.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP61224.1 - 7.8e-11 41.9 0.0 3.1e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP61224.1 - 4.7e-09 36.1 0.0 4.9e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ferric_reduct PF01794.14 OAP61226.1 - 6.9e-14 52.0 9.6 6.9e-14 52.0 6.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAP61226.1 - 1.3e-11 44.6 0.0 3.2e-11 43.3 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAP61226.1 - 0.0027 17.5 0.0 0.0069 16.2 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 OAP61226.1 - 0.044 14.3 0.0 12 6.5 0.0 2.4 1 1 0 2 2 2 0 Oxidoreductase NAD-binding domain Glyco_transf_8 PF01501.15 OAP61227.1 - 2.1e-34 118.9 0.0 3.6e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 OAP61227.1 - 0.038 13.3 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative Zip PF02535.17 OAP61227.1 - 8.9 5.2 11.7 14 4.6 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SNF2_N PF00176.18 OAP61228.1 - 4.3e-68 229.2 0.0 6.5e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 OAP61228.1 - 4e-13 49.2 0.0 8.6e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 OAP61228.1 - 5.8e-11 42.1 0.1 4e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 OAP61228.1 - 6.8e-10 38.6 13.3 1.8e-09 37.2 9.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP61228.1 - 6.7e-09 35.6 14.3 6.7e-09 35.6 9.9 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP61228.1 - 1.5e-08 34.1 12.0 1.5e-08 34.1 8.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP61228.1 - 1.1e-06 28.2 14.1 1.1e-06 28.2 9.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAP61228.1 - 3.1e-06 26.9 12.9 6.2e-06 25.9 8.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 OAP61228.1 - 7.9e-06 25.5 12.5 1.8e-05 24.3 8.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 OAP61228.1 - 4.2e-05 23.5 6.5 0.00012 22.1 4.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 OAP61228.1 - 0.0056 16.4 6.4 0.013 15.3 4.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 OAP61228.1 - 0.0062 16.2 9.1 0.017 14.7 6.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 OAP61228.1 - 0.013 15.3 3.6 0.033 14.0 2.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 OAP61228.1 - 0.016 14.7 8.9 0.018 14.5 5.3 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit HDA2-3 PF11496.3 OAP61228.1 - 0.028 13.2 0.1 0.41 9.4 0.0 2.6 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 zf-RING_4 PF14570.1 OAP61228.1 - 0.041 13.4 9.5 0.079 12.5 6.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 OAP61228.1 - 0.063 12.7 9.5 0.091 12.2 5.0 2.2 2 0 0 2 2 2 0 P-11 zinc finger K1377 PF15352.1 OAP61228.1 - 0.33 8.8 2.9 0.52 8.1 2.0 1.2 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy Prok-RING_4 PF14447.1 OAP61228.1 - 0.59 9.7 7.3 1.3 8.5 5.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RIX1 PF08167.7 OAP61229.1 - 9.5e-40 135.9 1.7 3e-39 134.3 0.5 2.2 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TPR_8 PF13181.1 OAP61230.1 - 1.1e-07 31.0 1.7 0.31 10.9 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP61230.1 - 7.2e-05 23.0 5.6 0.2 12.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAP61230.1 - 0.00043 19.8 6.4 2 8.1 0.3 5.0 5 0 0 5 5 5 1 TPR repeat TPR_2 PF07719.12 OAP61230.1 - 0.0011 18.6 11.9 2.6 8.1 0.1 6.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAP61230.1 - 0.002 18.7 10.0 0.88 10.3 0.2 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAP61230.1 - 0.0042 17.4 2.5 5.7 7.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAP61230.1 - 0.011 15.9 0.3 0.34 11.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP61230.1 - 0.046 13.6 8.5 0.32 10.9 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP61230.1 - 0.068 12.9 8.4 38 4.4 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP61230.1 - 0.21 12.3 15.3 3.4 8.5 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP61230.1 - 0.56 9.9 5.9 29 4.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Asp PF00026.18 OAP61231.1 - 9.2e-74 248.5 6.4 1.1e-73 248.2 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAP61231.1 - 1.9e-08 34.4 2.2 3.3e-08 33.6 0.3 2.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAP61231.1 - 2.8e-07 30.9 1.8 0.00041 20.7 0.3 3.4 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 OAP61231.1 - 5.8e-05 22.6 0.0 0.00016 21.2 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Abhydro_lipase PF04083.11 OAP61232.1 - 3.3e-22 77.6 0.1 6.6e-22 76.6 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 OAP61232.1 - 9.2e-19 67.9 2.3 3.6e-17 62.6 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP61232.1 - 0.00012 21.8 0.0 0.00053 19.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 OAP61232.1 - 0.00033 20.1 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Ku PF02735.11 OAP61233.1 - 3.7e-37 127.6 0.0 8.7e-37 126.4 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 OAP61233.1 - 6.9e-33 113.9 0.0 1e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 OAP61233.1 - 4.2e-15 56.0 0.0 1.3e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 OAP61233.1 - 1.6e-11 43.3 0.0 3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 SAP domain Complex1_51K PF01512.12 OAP61233.1 - 0.094 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Ferrochelatase PF00762.14 OAP61234.1 - 4.2e-93 311.7 0.0 5e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase adh_short_C2 PF13561.1 OAP61235.1 - 1.1e-30 107.2 0.3 1.3e-30 106.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP61235.1 - 1.7e-26 93.1 8.7 6.3e-25 88.0 6.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61235.1 - 4.7e-09 36.1 5.8 1.8e-08 34.2 4.0 1.7 1 1 0 1 1 1 1 KR domain LtrA PF06772.6 OAP61237.1 - 2.1e-11 43.3 9.4 4.1e-11 42.4 6.5 1.4 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) MFS_1 PF07690.11 OAP61238.1 - 1.6e-28 99.4 47.2 2e-27 95.8 18.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 OAP61238.1 - 4.9e-06 25.3 27.8 4.8e-05 22.0 0.1 3.1 2 1 1 3 3 3 3 Vacuole effluxer Atg22 like HemY_N PF07219.8 OAP61238.1 - 4.3 6.9 5.9 33 4.1 0.0 3.2 3 0 0 3 3 3 0 HemY protein N-terminus Pkinase PF00069.20 OAP61239.1 - 3.6e-70 236.0 0.0 6.4e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61239.1 - 1.7e-51 174.7 0.0 1.7e-51 174.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 OAP61239.1 - 3.5e-23 81.7 1.6 1.5e-22 79.7 0.1 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 OAP61239.1 - 7.9e-17 61.5 0.8 1.9e-16 60.3 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.1 OAP61239.1 - 2.2e-06 26.8 0.0 4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 OAP61239.1 - 3.3e-06 27.2 0.0 8.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.6 OAP61239.1 - 0.028 13.2 0.1 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 OAP61239.1 - 0.26 10.9 5.7 0.17 11.6 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.27 OAP61240.1 - 2e-36 122.5 2.9 2.3e-07 30.4 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 OAP61240.1 - 0.0003 20.2 0.0 0.74 9.3 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C25_C PF03785.9 OAP61240.1 - 0.06 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain adh_short_C2 PF13561.1 OAP61241.1 - 6.7e-22 78.4 0.0 8.1e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP61241.1 - 3.3e-14 53.1 0.0 4.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61241.1 - 1.2e-07 31.5 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 OAP61241.1 - 0.017 15.4 0.0 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 OAP61241.1 - 0.092 11.8 0.1 0.57 9.2 0.0 2.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 OAP61241.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAP61241.1 - 0.15 12.0 0.3 0.31 11.0 0.3 1.6 1 1 0 1 1 1 0 NADH(P)-binding FSH1 PF03959.8 OAP61242.1 - 9.9e-26 90.4 0.0 1.3e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 OAP61242.1 - 0.00028 20.8 0.0 0.037 13.8 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP61242.1 - 0.1 12.0 0.2 0.49 9.7 0.0 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase FlgD_ig PF13860.1 OAP61243.1 - 0.07 12.8 0.0 0.36 10.6 0.0 2.2 1 0 0 1 1 1 0 FlgD Ig-like domain SecE PF00584.15 OAP61243.1 - 0.11 12.1 1.1 0.21 11.1 0.8 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Mit_KHE1 PF10173.4 OAP61243.1 - 0.59 9.9 1.7 1.3 8.8 1.0 1.7 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related PIG-X PF08320.7 OAP61244.1 - 6.9e-62 208.4 0.0 9.9e-62 207.8 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 EST1_DNA_bind PF10373.4 OAP61247.1 - 8.8e-13 48.0 0.0 1.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain ALMS_motif PF15309.1 OAP61247.1 - 0.064 13.1 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 ALMS motif Mid1 PF12929.2 OAP61248.1 - 1.1e-144 482.3 3.5 1.4e-144 482.0 2.4 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 OAP61248.1 - 0.24 11.7 3.5 1.9 8.8 0.5 2.4 2 0 0 2 2 2 0 Fz domain Es2 PF09751.4 OAP61249.1 - 1.7e-83 281.3 4.2 2e-83 281.1 2.9 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 TPR_11 PF13414.1 OAP61250.1 - 4.7e-22 77.4 33.8 3.2e-05 23.4 0.5 11.6 7 2 5 13 13 13 8 TPR repeat TPR_2 PF07719.12 OAP61250.1 - 7.3e-17 59.8 28.9 0.015 15.2 0.2 13.0 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAP61250.1 - 2.2e-16 59.5 36.2 0.0012 18.7 0.2 11.6 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.1 OAP61250.1 - 4.2e-15 55.9 43.6 0.00011 22.8 0.0 11.5 9 2 2 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAP61250.1 - 3.4e-13 49.7 33.6 0.00012 22.3 0.6 9.8 6 3 4 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.1 OAP61250.1 - 5.6e-11 42.0 37.7 0.018 15.5 0.2 13.4 10 3 4 14 14 13 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAP61250.1 - 6e-11 41.3 18.6 0.28 11.0 0.3 10.1 11 0 0 11 11 11 3 Tetratricopeptide repeat Apc3 PF12895.2 OAP61250.1 - 1.3e-09 38.0 19.9 0.054 13.6 0.9 7.6 6 2 2 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 OAP61250.1 - 7e-09 34.9 28.7 0.003 17.0 0.2 11.5 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAP61250.1 - 4.1e-06 26.5 21.3 1.6 9.1 0.1 10.7 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP61250.1 - 0.017 14.8 21.1 0.28 11.1 0.3 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF2422 PF10337.4 OAP61250.1 - 0.059 12.1 3.1 0.13 11.0 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) TPR_3 PF07720.7 OAP61250.1 - 0.13 12.0 7.5 9.3 6.1 0.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP61250.1 - 0.28 11.7 29.6 2.6 8.6 0.1 11.7 13 0 0 13 13 12 0 Tetratricopeptide repeat DUF221 PF02714.10 OAP61251.1 - 1.1e-106 356.4 15.9 1.6e-106 355.8 11.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 OAP61251.1 - 1.2e-23 82.7 0.1 4.4e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 OAP61251.1 - 1.4e-14 54.3 0.1 3.4e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_5 PF13893.1 OAP61251.1 - 0.0059 16.4 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP61251.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.3 OAP61252.1 - 3.3e-08 32.5 3.4 7.9e-08 31.2 0.2 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 OAP61253.1 - 4.3e-51 173.8 7.0 5.1e-51 173.6 4.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61253.1 - 1.9e-07 30.1 24.8 9.7e-06 24.5 13.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B_N PF00033.14 OAP61253.1 - 0.054 12.8 7.1 0.1 11.9 4.9 1.5 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Sugar_tr PF00083.19 OAP61254.1 - 3.6e-34 118.1 5.0 3.6e-34 118.1 3.5 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61254.1 - 3.8e-11 42.2 11.9 3.8e-11 42.2 8.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAP61254.1 - 0.00022 20.7 1.2 0.00032 20.2 0.8 1.3 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 TRI12 PF06609.8 OAP61254.1 - 0.0012 17.1 1.1 0.0015 16.7 0.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 OAP61254.1 - 0.0022 16.7 0.3 0.0023 16.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 OAP61254.1 - 0.22 9.6 1.9 0.29 9.2 1.3 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector p450 PF00067.17 OAP61255.1 - 2.9e-63 214.0 0.0 3.6e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dioxygenase_C PF00775.16 OAP61257.1 - 4.8e-40 136.7 0.0 6e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 OAP61257.1 - 1.1e-16 60.5 0.0 2.6e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 OAP61257.1 - 0.00088 19.2 0.0 0.0024 17.8 0.0 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain ET PF01684.11 OAP61259.1 - 0.97 9.5 7.8 0.13 12.2 0.4 2.8 2 1 1 3 3 3 0 ET module DUF3433 PF11915.3 OAP61260.1 - 4.4e-13 49.1 0.1 1.5e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Zn_clus PF00172.13 OAP61261.1 - 0.00025 20.8 13.3 0.00051 19.9 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP61261.1 - 0.0017 16.9 2.5 0.0028 16.3 1.4 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 OAP61262.1 - 2e-16 60.5 0.2 3.1e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP61262.1 - 8.4e-08 32.0 0.1 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP61262.1 - 0.002 17.7 0.1 0.0063 16.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP61262.1 - 0.029 13.5 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2305 PF10230.4 OAP61262.1 - 0.037 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 OAP61262.1 - 0.14 11.9 0.1 0.49 10.2 0.1 1.9 1 1 0 1 1 1 0 Putative lysophospholipase RsgI_N PF12791.2 OAP61263.1 - 0.021 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma factor N-terminus HCV_NS4a PF01006.15 OAP61263.1 - 0.24 10.9 1.3 0.4 10.2 0.9 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DUF500 PF04366.7 OAP61264.1 - 4.3e-35 119.8 0.4 6.4e-35 119.3 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF500) HET PF06985.6 OAP61265.1 - 1.2e-14 54.5 0.0 1.7e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hydrophobin_2 PF06766.6 OAP61268.1 - 7.2e-25 86.4 9.7 7.2e-25 86.4 6.7 1.5 2 0 0 2 2 2 1 Fungal hydrophobin Hydrolase PF00702.21 OAP61269.1 - 1.3e-30 107.4 0.1 2.9e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 OAP61269.1 - 2.3e-22 79.1 0.0 4.5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAP61269.1 - 8.3e-10 39.1 0.0 2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 OAP61269.1 - 4.5e-06 26.7 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF4124 PF13511.1 OAP61270.1 - 4.3 7.4 8.6 22 5.1 3.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4124) MFS_1 PF07690.11 OAP61271.1 - 1.5e-27 96.2 22.4 1.5e-27 96.2 15.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Herpes_LMP1 PF05297.6 OAP61271.1 - 0.14 11.0 1.7 0.44 9.4 1.2 1.8 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FAD_binding_3 PF01494.14 OAP61272.1 - 1.5e-14 53.8 0.1 8.3e-14 51.4 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 OAP61272.1 - 3.5e-09 36.0 0.4 7.1e-09 34.9 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 OAP61272.1 - 6.5e-08 31.8 0.1 9.2e-06 24.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP61272.1 - 9.8e-08 32.1 0.0 2.4e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP61272.1 - 6.3e-07 28.2 0.1 1.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 OAP61272.1 - 8.6e-06 25.6 0.1 3.4e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 OAP61272.1 - 9.5e-06 24.9 0.2 1.7e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 OAP61272.1 - 0.00011 21.1 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 OAP61272.1 - 0.00044 20.6 0.3 0.075 13.4 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP61272.1 - 0.0025 17.8 0.1 0.0072 16.4 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP61272.1 - 0.02 13.9 0.1 0.04 13.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 OAP61272.1 - 0.024 13.5 1.4 0.062 12.2 0.2 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 OAP61272.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.17 OAP61273.1 - 3.8e-75 253.1 0.0 4.7e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ank_5 PF13857.1 OAP61274.1 - 4.7e-07 29.8 0.2 1.1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 OAP61274.1 - 0.0089 15.8 0.3 0.021 14.6 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 OAP61274.1 - 0.028 14.6 0.1 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.2 OAP61274.1 - 0.096 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) PilP PF04351.8 OAP61274.1 - 0.17 11.7 1.9 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 Pilus assembly protein, PilP CBP4 PF07960.6 OAP61274.1 - 1.1 8.8 8.0 8.7 5.9 0.8 2.9 2 0 0 2 2 2 0 CBP4 PARP PF00644.15 OAP61275.1 - 4.2e-58 196.1 0.0 1.3e-57 194.5 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 OAP61275.1 - 4.5e-40 136.4 0.4 6.9e-40 135.8 0.3 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 OAP61275.1 - 3.1e-20 71.8 0.2 6.7e-20 70.8 0.2 1.5 1 0 0 1 1 1 1 WGR domain PTCB-BRCT PF12738.2 OAP61275.1 - 0.019 14.7 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.21 OAP61275.1 - 0.073 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain API5 PF05918.6 OAP61276.1 - 5.3 5.4 7.4 6.9 5.0 5.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Macoilin PF09726.4 OAP61276.1 - 5.5 5.1 12.9 6.7 4.8 9.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DER1 PF04511.10 OAP61277.1 - 1.1e-25 90.3 2.6 1.2e-25 90.1 1.8 1.0 1 0 0 1 1 1 1 Der1-like family DKCLD PF08068.7 OAP61278.1 - 3.6e-24 84.4 3.7 1.4e-22 79.3 0.1 3.5 4 0 0 4 4 4 1 DKCLD (NUC011) domain TruB_N PF01509.13 OAP61278.1 - 4.2e-24 85.4 0.2 2.9e-21 76.1 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 OAP61278.1 - 7.6e-21 73.6 1.4 1.5e-20 72.6 1.0 1.5 1 0 0 1 1 1 1 PUA domain GAGA_bind PF06217.7 OAP61278.1 - 0.075 12.9 4.3 0.11 12.4 3.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_DNAp_acc PF04929.7 OAP61278.1 - 1.2 7.9 7.3 1.8 7.4 5.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RR_TM4-6 PF06459.7 OAP61278.1 - 7.3 6.3 16.7 10 5.8 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 OAP61278.1 - 8.4 6.0 25.1 14 5.3 17.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Pkinase PF00069.20 OAP61279.1 - 7.6e-63 212.0 0.0 1.1e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61279.1 - 5.6e-26 91.1 0.0 7.7e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAP61279.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAP61279.1 - 0.018 14.0 0.0 0.038 12.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 OAP61279.1 - 0.027 14.2 0.5 2.3 7.8 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family BAR PF03114.13 OAP61281.1 - 3.5e-56 190.2 2.4 5.2e-56 189.7 1.6 1.2 1 0 0 1 1 1 1 BAR domain SH3BP5 PF05276.9 OAP61281.1 - 0.033 13.5 2.8 0.071 12.4 0.3 2.1 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) FliD_N PF02465.13 OAP61281.1 - 0.09 13.1 1.8 5.9 7.3 0.4 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Mgr1 PF08602.5 OAP61281.1 - 0.096 11.6 1.4 2.2 7.1 0.0 2.0 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Arfaptin PF06456.8 OAP61281.1 - 0.41 9.9 4.2 2 7.7 2.9 2.0 1 1 0 1 1 1 0 Arfaptin-like domain ETF PF01012.16 OAP61282.1 - 1.3e-40 138.8 0.4 2e-40 138.2 0.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SSXRD PF09514.5 OAP61282.1 - 0.088 12.1 0.3 0.19 11.0 0.2 1.5 1 0 0 1 1 1 0 SSXRD motif Skp1 PF01466.14 OAP61283.1 - 1.3e-39 134.0 2.0 2e-39 133.4 1.4 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 OAP61283.1 - 9e-24 83.3 0.3 2e-23 82.2 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 OAP61283.1 - 0.013 15.5 0.4 0.021 14.8 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DUF2385 PF09539.5 OAP61285.1 - 0.059 13.7 1.0 2.2 8.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) NSP13 PF06460.7 OAP61285.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NSP13 Glyco_trans_2_3 PF13632.1 OAP61286.1 - 1e-44 152.5 4.8 1e-44 152.5 3.3 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAP61286.1 - 3e-08 33.7 0.0 1.9e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 OAP61286.1 - 0.0006 19.5 0.0 0.0022 17.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 OAP61286.1 - 0.0024 17.1 0.0 0.0079 15.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_22 PF03901.12 OAP61287.1 - 3.1e-61 207.6 23.8 4.4e-61 207.1 16.5 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_16 PF00722.16 OAP61287.1 - 4.9e-19 68.3 3.6 1.3e-18 66.9 2.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 XPC-binding PF09280.6 OAP61288.1 - 1.5e-21 75.5 11.9 2.9e-21 74.6 8.2 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 OAP61288.1 - 2.1e-19 68.6 0.1 3.1e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 OAP61288.1 - 1.8e-17 62.5 0.3 1.8e-09 37.1 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain Rad60-SLD PF11976.3 OAP61288.1 - 1.2e-08 34.4 0.2 1.9e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAP61288.1 - 0.00088 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 OAP61288.1 - 0.0043 16.9 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 OAP61288.1 - 0.024 14.2 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Pex14_N PF04695.8 OAP61288.1 - 0.046 13.7 7.5 3.7 7.5 2.5 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ubiquitin_2 PF14560.1 OAP61288.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Rap1_C PF11626.3 OAP61288.1 - 0.058 13.2 0.0 6 6.8 0.0 2.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Med6 PF04934.9 OAP61289.1 - 1e-33 115.8 0.0 1.5e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Mito_fiss_reg PF05308.6 OAP61289.1 - 5.3 6.3 11.2 0.053 12.8 1.8 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Chorismate_bind PF00425.13 OAP61290.1 - 1.7e-61 207.8 0.2 5e-61 206.2 0.1 1.8 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 OAP61290.1 - 4.8e-27 94.6 0.0 5.8e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 OAP61290.1 - 5.1e-18 65.4 0.0 7.1e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 OAP61290.1 - 6.3e-07 29.0 0.5 9.9e-06 25.1 0.4 2.3 1 1 0 1 1 1 1 Peptidase C26 Methyltransf_11 PF08241.7 OAP61291.1 - 2.2e-24 85.7 0.0 4.5e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP61291.1 - 1.2e-19 70.4 0.0 1.6e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP61291.1 - 4e-17 62.3 0.2 7.8e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP61291.1 - 8e-16 58.3 0.0 2.2e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP61291.1 - 2.2e-15 56.8 0.0 4.7e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61291.1 - 2.3e-15 57.1 0.0 5.5e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP61291.1 - 2.8e-14 53.1 0.0 4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP61291.1 - 3.1e-13 49.3 0.0 5.2e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAP61291.1 - 1.4e-07 31.0 0.0 2.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 OAP61291.1 - 1.1e-05 25.0 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 OAP61291.1 - 1.4e-05 24.5 0.0 6.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 OAP61291.1 - 2.4e-05 23.6 0.0 0.0016 17.7 0.0 2.3 1 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.6 OAP61291.1 - 6.3e-05 22.4 0.0 0.00019 20.9 0.0 1.7 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 OAP61291.1 - 0.00058 18.9 0.0 0.017 14.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase RrnaAD PF00398.15 OAP61291.1 - 0.0016 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 OAP61291.1 - 0.0016 17.6 0.0 0.0055 15.8 0.0 1.9 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 OAP61291.1 - 0.0016 18.0 0.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 OAP61291.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 OAP61291.1 - 0.0023 16.7 0.0 0.0039 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DUF938 PF06080.7 OAP61291.1 - 0.0037 16.8 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_24 PF13578.1 OAP61291.1 - 0.012 16.4 0.0 0.042 14.6 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_29 PF03141.11 OAP61291.1 - 0.017 13.4 0.0 0.027 12.8 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 OAP61291.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_PK PF05891.7 OAP61291.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 OAP61291.1 - 0.026 13.6 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 OAP61291.1 - 0.043 13.7 0.0 0.086 12.8 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase FmrO PF07091.6 OAP61291.1 - 0.069 12.1 0.0 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) DUF3684 PF12449.3 OAP61292.1 - 0 1390.0 0.0 0 1389.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 OAP61292.1 - 6e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAP61292.1 - 0.00018 21.2 0.0 0.00046 19.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRAPPC9-Trs120 PF08626.6 OAP61293.1 - 4.2e-109 365.5 0.0 4.9e-108 362.0 0.0 2.5 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit HA2 PF04408.18 OAP61294.1 - 4.8e-16 58.6 2.1 7.5e-16 58.0 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAP61294.1 - 9.9e-12 44.5 0.0 2.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP61294.1 - 6e-10 38.8 0.0 9.7e-08 31.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 OAP61294.1 - 1.7e-08 34.2 0.0 4.7e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 OAP61294.1 - 0.00068 19.7 0.2 0.0039 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 OAP61294.1 - 0.0019 18.0 1.5 1.1 9.0 0.0 3.5 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_19 PF13245.1 OAP61294.1 - 0.031 14.0 0.1 0.086 12.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 OAP61294.1 - 0.53 10.5 17.3 0.26 11.5 0.3 3.2 3 1 0 3 3 3 0 AAA domain APH PF01636.18 OAP61295.1 - 6.6e-15 55.5 0.0 7.6e-14 52.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 OAP61295.1 - 0.00033 19.4 0.0 0.003 16.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 OAP61295.1 - 0.002 17.7 0.2 0.0045 16.5 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 OAP61295.1 - 0.047 12.8 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Big_3_3 PF13750.1 OAP61295.1 - 0.13 11.6 0.0 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) T5orf172 PF10544.4 OAP61296.1 - 2e-17 63.4 1.0 3.8e-17 62.4 0.7 1.5 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 OAP61296.1 - 5.6e-15 55.5 3.1 1.5e-14 54.1 2.2 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 HET PF06985.6 OAP61297.1 - 1.8e-22 80.0 7.4 3e-19 69.5 5.2 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 OAP61299.1 - 4e-09 36.0 0.1 7.6e-09 35.0 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61299.1 - 4.7e-08 32.4 0.0 6.8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAP61299.1 - 0.016 14.2 0.2 0.024 13.7 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP61299.1 - 0.023 14.4 0.7 0.074 12.7 0.2 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP61299.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase p450 PF00067.17 OAP61300.1 - 9.7e-54 182.6 0.0 3.6e-53 180.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 CRCB PF02537.10 OAP61301.1 - 7e-29 100.0 14.4 7.4e-18 64.5 4.6 3.5 3 0 0 3 3 3 3 CrcB-like protein adh_short_C2 PF13561.1 OAP61302.1 - 1e-27 97.4 0.0 1.2e-27 97.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP61302.1 - 1.2e-26 93.6 0.0 1.5e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61302.1 - 1.4e-12 47.6 0.0 1.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Phosphodiest PF01663.17 OAP61303.1 - 6e-15 55.4 0.2 9.9e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 OAP61303.1 - 3.3e-05 23.4 0.5 5.8e-05 22.6 0.4 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 OAP61303.1 - 8e-05 21.9 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Gly-zipper_YMGG PF13441.1 OAP61303.1 - 0.14 11.7 11.2 0.32 10.5 7.7 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper zf-CCCH PF00642.19 OAP61304.1 - 3.8e-08 32.8 2.4 6.7e-08 32.0 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 OAP61304.1 - 5.3e-08 32.4 4.5 8.5e-08 31.7 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP61304.1 - 1.3e-07 31.5 9.9 2.3e-07 30.7 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP61304.1 - 4.1e-06 26.4 8.2 7.1e-06 25.6 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAP61304.1 - 1.7e-05 24.5 6.5 2.8e-05 23.8 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAP61304.1 - 1.8e-05 24.2 9.8 3.4e-05 23.4 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAP61304.1 - 0.00047 19.8 2.2 0.0014 18.3 1.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAP61304.1 - 0.0042 16.9 8.1 0.0098 15.7 5.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF903 PF06004.7 OAP61304.1 - 0.024 14.1 1.4 0.034 13.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) DUF4630 PF15443.1 OAP61304.1 - 0.19 11.5 2.8 0.12 12.2 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) Prok-RING_4 PF14447.1 OAP61304.1 - 0.2 11.2 3.4 0.38 10.3 2.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PolC_DP2 PF03833.8 OAP61304.1 - 0.25 8.9 2.9 0.34 8.5 2.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 SOG2 PF10428.4 OAP61304.1 - 2 7.0 6.2 21 3.5 4.4 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein Cript PF10235.4 OAP61304.1 - 3.4 8.0 9.4 2.9 8.3 5.0 2.1 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT CN_hydrolase PF00795.17 OAP61305.1 - 6e-15 55.0 0.1 8.8e-14 51.2 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase HLH PF00010.21 OAP61306.1 - 3.8e-10 39.3 0.6 6.9e-10 38.4 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2229 PF09989.4 OAP61306.1 - 0.035 13.5 0.4 0.07 12.5 0.1 1.5 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2235 PF09994.4 OAP61307.1 - 4.7e-65 219.7 0.0 8.8e-65 218.8 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) But2 PF09792.4 OAP61308.1 - 6.1e-27 94.1 0.5 1.3e-26 93.0 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain GATase_2 PF00310.16 OAP61309.1 - 1.5e-19 69.9 0.0 1.8e-14 53.2 0.0 2.9 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAP61309.1 - 1.1e-16 61.0 0.1 3.8e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 OAP61309.1 - 5.2e-15 55.2 0.1 2.2e-14 53.2 0.0 2.1 3 0 0 3 3 3 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 OAP61309.1 - 1.7e-12 47.1 0.1 3.5e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 OAP61309.1 - 3.2e-05 22.7 0.0 6.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.1 OAP61309.1 - 0.025 13.8 0.0 0.061 12.6 0.0 1.5 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_methylase PF00145.12 OAP61310.1 - 3e-39 135.0 0.0 1.2e-26 93.6 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 OAP61310.1 - 0.0011 19.0 0.0 0.0043 17.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 OAP61310.1 - 0.038 13.5 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 OAP61310.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RNase_PH PF01138.16 OAP61311.1 - 2.7e-19 69.7 0.0 9.6e-19 68.0 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 FAD_binding_3 PF01494.14 OAP61312.1 - 6.3e-71 239.2 0.0 9e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 OAP61312.1 - 1.5e-48 164.5 0.0 4.5e-48 163.0 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 OAP61312.1 - 0.0032 16.3 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 OAP61312.1 - 0.0035 16.2 2.1 0.27 10.1 0.2 3.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP61312.1 - 0.017 14.0 0.7 0.037 12.8 0.5 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 OAP61312.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 OAP61312.1 - 0.033 14.0 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP61312.1 - 0.059 13.3 0.0 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Phosphodiest PF01663.17 OAP61313.1 - 1.5e-16 60.7 0.8 2.9e-15 56.4 0.6 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 OAP61313.1 - 0.027 13.6 0.2 0.082 12.0 0.0 1.8 2 0 0 2 2 2 0 Sulfatase Methyltransf_23 PF13489.1 OAP61314.1 - 3e-12 46.5 0.0 4.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP61314.1 - 0.0075 16.7 0.0 0.052 14.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP61314.1 - 0.019 15.4 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 OAP61315.1 - 2.8e-69 233.8 0.0 3.2e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SAP PF02037.22 OAP61316.1 - 4.5e-08 32.3 0.2 9.1e-08 31.4 0.1 1.6 1 0 0 1 1 1 1 SAP domain RAI1 PF08652.6 OAP61317.1 - 2e-26 91.5 0.0 6e-26 90.0 0.0 1.8 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease HrpB_C PF08482.5 OAP61317.1 - 0.088 12.9 0.1 0.36 10.9 0.0 2.0 2 1 0 2 2 2 0 ATP-dependent helicase C-terminal LT-IIB PF06453.6 OAP61317.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) IPPT PF01715.12 OAP61318.1 - 5.1e-52 176.3 0.2 1.6e-51 174.8 0.1 1.7 1 1 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 OAP61318.1 - 1.1e-07 32.7 1.0 1.7e-06 28.8 0.5 2.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP61318.1 - 1.4e-06 28.6 3.2 0.0012 19.1 0.4 3.0 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.1 OAP61318.1 - 4.1e-05 23.4 0.5 0.0021 17.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain IPT PF01745.11 OAP61318.1 - 7.6e-05 21.9 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase AAA_16 PF13191.1 OAP61318.1 - 0.00058 19.8 1.7 0.057 13.3 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain zf-C2H2_jaz PF12171.3 OAP61318.1 - 0.0097 16.0 0.1 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_22 PF13401.1 OAP61318.1 - 0.0099 16.0 0.0 0.062 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain zf-met PF12874.2 OAP61318.1 - 0.02 15.0 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAP61318.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_5 PF07728.9 OAP61318.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 OAP61318.1 - 0.026 14.4 0.2 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain zf-C2H2_6 PF13912.1 OAP61318.1 - 0.043 13.7 0.1 0.091 12.7 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger GAGA PF09237.6 OAP61318.1 - 0.072 12.6 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 GAGA factor AAA PF00004.24 OAP61318.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hpr_kinase_C PF07475.7 OAP61318.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PPV_E1_C PF00519.12 OAP61318.1 - 0.078 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_25 PF13481.1 OAP61318.1 - 0.084 12.2 0.1 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 OAP61318.1 - 0.093 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Aconitase_2_N PF06434.8 OAP61318.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus RNA_helicase PF00910.17 OAP61318.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RRM_1 PF00076.17 OAP61319.1 - 7.6e-08 31.8 0.0 1.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP61319.1 - 2.7e-06 27.1 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP61319.1 - 0.00017 21.4 0.1 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAP61319.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 OAP61319.1 - 0.13 11.9 2.3 0.23 11.2 1.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glyco_hydro_63 PF03200.11 OAP61320.1 - 1.7e-238 793.5 0.0 1.6e-237 790.2 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Pkinase PF00069.20 OAP61321.1 - 5.8e-67 225.5 0.6 5.2e-36 124.1 0.0 4.2 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61321.1 - 6.5e-38 130.2 0.0 2.1e-17 63.0 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 OAP61321.1 - 2e-16 59.9 4.8 8.1e-16 57.9 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 OAP61321.1 - 1.4e-15 57.1 1.0 1.6e-13 50.4 0.0 2.6 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 OAP61321.1 - 5.4e-10 39.1 0.1 2.2e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 RWD domain APH PF01636.18 OAP61321.1 - 0.0015 18.3 0.0 0.0048 16.6 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAP61321.1 - 0.015 14.3 0.0 0.15 10.9 0.0 2.5 3 0 0 3 3 3 0 Kinase-like TGS PF02824.16 OAP61322.1 - 3.7e-21 74.7 0.5 6.9e-21 73.8 0.1 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 OAP61322.1 - 1.4e-19 70.1 0.1 4.4e-19 68.5 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP61322.1 - 7.2e-14 51.3 0.0 1.2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAP61322.1 - 2.1e-05 24.4 0.3 0.035 13.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 OAP61322.1 - 0.00082 19.8 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 OAP61322.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 OAP61322.1 - 0.052 12.3 0.0 0.13 11.0 0.0 1.7 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 OAP61322.1 - 0.086 13.1 2.0 1.8 8.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain MCM PF00493.18 OAP61322.1 - 0.096 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family Med29 PF11568.3 OAP61322.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 29 DAO PF01266.19 OAP61323.1 - 2e-51 175.0 0.8 2.3e-50 171.5 0.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP61323.1 - 9.9e-05 22.2 0.3 0.00027 20.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAP61323.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP61323.1 - 0.015 13.9 0.1 0.075 11.6 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Strep_67kDa_ant PF06100.6 OAP61323.1 - 0.051 11.9 0.1 0.078 11.3 0.1 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family GIDA PF01134.17 OAP61323.1 - 0.17 10.7 0.0 3.6 6.3 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A CRT10 PF08728.5 OAP61324.1 - 1.7e-19 69.3 0.1 8.1e-12 43.9 0.0 2.7 3 0 0 3 3 3 2 CRT10 MMtag PF10159.4 OAP61325.1 - 7.7e-33 112.3 4.7 1.4e-32 111.5 3.3 1.4 1 0 0 1 1 1 1 Kinase phosphorylation protein adh_short PF00106.20 OAP61326.1 - 7.7e-10 38.9 0.0 1.9e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP61326.1 - 1.2e-07 31.7 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CLPTM1 PF05602.7 OAP61327.1 - 8.7e-168 558.5 0.4 1.1e-167 558.2 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1453 PF07301.6 OAP61327.1 - 0.03 14.1 2.4 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) DUF4044 PF13253.1 OAP61327.1 - 0.092 11.9 1.0 0.33 10.1 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Zip PF02535.17 OAP61327.1 - 0.093 11.7 0.0 0.59 9.0 0.0 2.1 3 0 0 3 3 3 0 ZIP Zinc transporter DUF1240 PF06836.7 OAP61327.1 - 0.22 11.7 4.7 0.71 10.1 3.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) eIF-5_eIF-2B PF01873.12 OAP61328.1 - 0.0016 18.1 1.5 0.0023 17.6 1.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Transcrip_reg PF01709.15 OAP61330.1 - 5.4e-57 192.6 2.2 6e-57 192.4 1.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF3646 PF12362.3 OAP61330.1 - 0.0075 16.2 0.8 0.032 14.1 0.4 2.0 1 1 1 2 2 2 1 DNA polymerase III gamma and tau subunits C terminal DUF2711 PF10924.3 OAP61330.1 - 0.06 12.8 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) PTR2 PF00854.16 OAP61331.1 - 8e-38 130.1 5.7 2.7e-36 125.1 4.0 2.4 1 1 0 1 1 1 1 POT family Vps51 PF08700.6 OAP61331.1 - 5.1e-10 39.0 0.1 2.7e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 MFS_1 PF07690.11 OAP61331.1 - 9.6e-07 27.8 24.4 9.6e-07 27.8 16.9 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily FUN14 PF04930.10 OAP61332.1 - 2.4e-08 34.1 0.2 4.4e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 FUN14 family DUF1622 PF07784.6 OAP61332.1 - 0.068 12.8 0.6 4.5 6.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1622) DUF4321 PF14209.1 OAP61332.1 - 2.8 7.7 6.3 6.3 6.5 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4321) FAD_binding_3 PF01494.14 OAP61333.1 - 4.2e-82 276.0 0.0 6.8e-82 275.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP61333.1 - 0.033 13.1 0.0 3 6.6 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP61333.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4192 PF13830.1 OAP61334.1 - 0.033 13.8 1.7 0.071 12.7 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) IncA PF04156.9 OAP61336.1 - 0.00029 20.4 46.2 0.089 12.3 12.8 3.2 1 1 2 3 3 3 3 IncA protein TPR_MLP1_2 PF07926.7 OAP61336.1 - 0.00035 20.3 42.4 0.0018 18.0 3.2 4.4 2 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Mod_r PF07200.8 OAP61336.1 - 0.0029 17.5 35.1 0.41 10.5 5.7 5.2 1 1 2 5 5 5 4 Modifier of rudimentary (Mod(r)) protein DUF904 PF06005.7 OAP61336.1 - 0.014 15.6 30.2 0.63 10.3 1.5 5.5 4 1 1 5 5 5 0 Protein of unknown function (DUF904) Myosin_tail_1 PF01576.14 OAP61336.1 - 0.36 8.4 36.5 0.59 7.7 2.3 3.0 1 1 1 3 3 3 0 Myosin tail Filament PF00038.16 OAP61336.1 - 0.43 9.9 35.5 0.19 11.1 1.9 2.8 1 1 1 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 OAP61336.1 - 0.45 10.8 31.8 0.79 10.0 2.0 5.0 1 1 3 4 4 4 0 Protein of unknown function (DUF972) TSC22 PF01166.13 OAP61336.1 - 0.49 10.4 13.0 0.86 9.6 0.1 4.9 5 0 0 5 5 5 0 TSC-22/dip/bun family Spc7 PF08317.6 OAP61336.1 - 0.51 8.9 34.0 0.26 9.9 4.5 3.2 1 1 3 4 4 4 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 OAP61336.1 - 0.67 9.9 25.2 0.44 10.5 1.1 5.1 3 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.4 OAP61336.1 - 0.81 9.8 18.6 2.9 8.0 1.1 4.4 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 OAP61336.1 - 1 8.3 37.2 0.91 8.5 10.0 2.6 2 1 0 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 OAP61336.1 - 1.7 8.6 37.9 0.44 10.4 2.4 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) DUF3573 PF12097.3 OAP61336.1 - 2.2 6.7 12.2 1.6 7.2 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) MCPsignal PF00015.16 OAP61336.1 - 2.5 7.5 20.7 0.73 9.3 3.2 3.0 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fez1 PF06818.10 OAP61336.1 - 4.6 7.2 35.2 4.9 7.1 8.4 2.4 2 0 0 2 2 2 0 Fez1 Lebercilin PF15619.1 OAP61336.1 - 6.7 6.0 33.1 1.9 7.8 1.6 4.5 3 1 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Reo_sigmaC PF04582.7 OAP61336.1 - 8.1 5.5 11.1 8.5 5.4 0.5 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein GATase PF00117.23 OAP61337.1 - 2e-45 154.5 0.0 2.8e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 OAP61337.1 - 6.9e-45 151.7 0.0 1.3e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 OAP61337.1 - 1.5e-05 24.5 0.1 0.00093 18.6 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 Fungal_trans_2 PF11951.3 OAP61338.1 - 4.1e-05 22.3 0.0 0.00019 20.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61338.1 - 0.0099 15.7 0.6 0.018 14.9 0.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP61341.1 - 2e-17 62.9 0.1 4.4e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP61342.1 - 5.2e-23 81.3 43.2 5.2e-23 81.3 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily D123 PF07065.9 OAP61343.1 - 6.7e-92 307.7 0.0 1.4e-90 303.4 0.0 2.3 1 1 0 1 1 1 1 D123 Cut12 PF11500.3 OAP61344.1 - 3.8e-07 29.9 2.7 1.1e-06 28.4 1.9 1.7 1 0 0 1 1 1 1 Spindle pole body formation-associated protein HAUS-augmin3 PF14932.1 OAP61344.1 - 0.0073 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 CENP-Q PF13094.1 OAP61344.1 - 0.023 14.7 2.1 0.035 14.1 0.8 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HAUS6_N PF14661.1 OAP61344.1 - 0.17 11.2 2.4 0.34 10.2 1.6 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF972 PF06156.8 OAP61344.1 - 0.17 12.2 1.2 0.47 10.8 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1640 PF07798.6 OAP61345.1 - 2.1e-10 40.9 4.2 4.4e-10 39.8 2.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4407 PF14362.1 OAP61345.1 - 8.8 5.1 13.8 2.8 6.8 5.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) 2-Hacid_dh_C PF02826.14 OAP61346.1 - 9.4e-51 171.4 0.0 1.8e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP61346.1 - 1.8e-15 56.5 0.0 2.6e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP61346.1 - 0.0017 18.2 0.0 0.0052 16.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase FimP PF09766.4 OAP61347.1 - 1.2e-07 31.1 0.8 1.2e-07 31.1 0.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein Pex14_N PF04695.8 OAP61347.1 - 0.00068 19.6 8.7 0.00096 19.2 6.1 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region EIIBC-GUT_N PF03612.9 OAP61347.1 - 0.014 15.0 1.5 0.016 14.8 1.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Suf PF05843.9 OAP61347.1 - 0.018 14.7 5.7 0.022 14.5 4.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Raftlin PF15250.1 OAP61347.1 - 0.021 13.3 3.3 0.026 13.0 2.3 1.0 1 0 0 1 1 1 0 Raftlin LIM_bind PF01803.11 OAP61347.1 - 0.056 12.5 6.7 0.073 12.1 4.6 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Dpy19 PF10034.4 OAP61347.1 - 0.069 11.3 0.4 0.082 11.0 0.3 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF3464 PF11947.3 OAP61347.1 - 0.094 12.1 1.3 0.13 11.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Spt20 PF12090.3 OAP61347.1 - 0.1 11.9 8.0 0.13 11.5 5.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF2232 PF09991.4 OAP61347.1 - 0.17 10.8 0.8 0.22 10.4 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PAT1 PF09770.4 OAP61347.1 - 0.29 9.3 17.1 0.35 9.0 11.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4199 PF13858.1 OAP61347.1 - 0.3 11.0 1.0 0.34 10.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) FHIPEP PF00771.15 OAP61347.1 - 0.62 8.3 3.0 0.79 7.9 2.1 1.1 1 0 0 1 1 1 0 FHIPEP family Peptidase_S49_N PF08496.5 OAP61347.1 - 0.62 9.8 6.9 0.91 9.3 4.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ofd1_CTDD PF10637.4 OAP61347.1 - 0.73 8.9 5.7 1 8.4 3.4 1.4 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term BAF1_ABF1 PF04684.8 OAP61347.1 - 1.2 7.8 23.9 1.8 7.3 16.3 1.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Dicty_REP PF05086.7 OAP61347.1 - 1.3 6.6 4.1 1.5 6.4 2.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FCP1_C PF09309.5 OAP61347.1 - 2.2 7.5 8.4 3.3 6.9 5.8 1.2 1 0 0 1 1 1 0 FCP1, C-terminal RRP14 PF15459.1 OAP61347.1 - 3.1 7.9 12.4 5.2 7.2 8.6 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 DUF4557 PF15101.1 OAP61347.1 - 4 7.2 17.3 2 8.2 10.6 1.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4557) Shisa PF13908.1 OAP61347.1 - 5.8 7.0 10.3 9.1 6.4 7.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator F-box PF00646.28 OAP61348.1 - 6.7e-07 28.8 0.6 4.9e-06 26.0 0.4 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 OAP61348.1 - 6e-06 25.8 0.4 1.8e-05 24.3 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 OAP61348.1 - 0.14 11.8 0.2 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain SOR_SNZ PF01680.12 OAP61349.1 - 1.9e-109 364.0 6.8 2.9e-109 363.4 4.7 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 OAP61349.1 - 8.1e-07 28.3 12.2 4.6e-06 25.9 2.0 2.5 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 OAP61349.1 - 0.00029 19.7 0.5 0.098 11.4 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 OAP61349.1 - 0.00029 20.1 0.9 0.023 13.9 0.0 3.0 2 1 1 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 OAP61349.1 - 0.0011 18.0 0.9 0.022 13.7 0.0 2.6 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 OAP61349.1 - 0.0056 15.7 0.2 0.052 12.6 0.0 2.2 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 OAP61349.1 - 0.0096 15.1 1.4 0.0096 15.1 1.0 2.4 2 1 0 2 2 2 1 Nitronate monooxygenase ORC2 PF04084.9 OAP61350.1 - 1.5e-89 300.0 0.0 2.6e-89 299.3 0.0 1.3 1 1 0 1 1 1 1 Origin recognition complex subunit 2 Cohesin_HEAT PF12765.2 OAP61350.1 - 0.058 13.3 0.5 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion ArgJ PF01960.13 OAP61351.1 - 4.8e-142 472.9 1.2 5.5e-142 472.7 0.8 1.0 1 0 0 1 1 1 1 ArgJ family HTH_16 PF12645.2 OAP61351.1 - 0.069 13.0 0.0 0.39 10.6 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain SecY PF00344.15 OAP61352.1 - 5.6e-95 318.2 8.9 6.9e-95 317.8 6.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 OAP61352.1 - 3.8e-18 64.6 0.3 1.1e-17 63.1 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p SdpI PF13630.1 OAP61352.1 - 2.3 7.9 6.8 0.48 10.1 0.1 3.3 3 0 0 3 3 3 0 SdpI/YhfL protein family FMN_bind_2 PF04299.7 OAP61353.1 - 5.9e-54 182.0 0.1 7.3e-54 181.7 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain SEN1_N PF12726.2 OAP61354.1 - 6.6e-166 553.4 7.6 9.2e-166 552.9 5.2 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 OAP61354.1 - 7.7e-68 228.5 0.1 7.7e-68 228.5 0.1 2.1 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 OAP61354.1 - 1.7e-61 207.1 0.0 4.7e-61 205.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP61354.1 - 8e-11 41.5 0.1 2.1e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAP61354.1 - 3.2e-08 33.4 0.1 3.9e-05 23.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 OAP61354.1 - 2e-05 24.2 0.1 0.054 13.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 OAP61354.1 - 0.00026 21.4 0.6 0.0032 17.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 OAP61354.1 - 0.0035 16.7 0.1 0.0095 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAP61354.1 - 0.077 12.5 0.2 0.19 11.2 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CCHC_4 PF14392.1 OAP61354.1 - 3.1 7.5 15.9 2.1 8.0 0.5 3.9 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC PF00098.18 OAP61354.1 - 5 7.2 16.4 0.73 9.8 1.6 3.4 3 0 0 3 3 3 0 Zinc knuckle E1-E2_ATPase PF00122.15 OAP61355.1 - 3.3e-13 49.2 0.0 2.1e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 OAP61355.1 - 1.1e-11 45.2 0.0 3.5e-11 43.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP61355.1 - 3.4e-11 42.9 0.0 8.8e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 OAP61355.1 - 6.8e-11 42.9 1.2 4.6e-09 37.0 0.8 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAP61355.1 - 0.026 14.1 0.3 0.049 13.1 0.2 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ApbA PF02558.11 OAP61356.1 - 3e-26 91.6 0.0 4.4e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 OAP61356.1 - 6.1e-21 74.7 0.0 9.6e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal bZIP_1 PF00170.16 OAP61357.1 - 1.2e-08 34.8 4.8 1.8e-08 34.1 3.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 OAP61357.1 - 7.3e-05 22.4 1.3 0.00016 21.3 0.9 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_Maf PF03131.12 OAP61357.1 - 0.00055 20.1 5.7 0.00094 19.4 4.0 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 OAP61357.1 - 0.00076 19.2 9.3 0.0021 17.8 6.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Prefoldin_2 PF01920.15 OAP61357.1 - 0.067 12.9 0.7 0.099 12.4 0.5 1.2 1 0 0 1 1 1 0 Prefoldin subunit SOG2 PF10428.4 OAP61358.1 - 7.7e-87 291.7 0.1 7.7e-87 291.7 0.0 2.5 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 OAP61358.1 - 1.6e-14 53.1 11.4 1.4e-06 27.7 0.1 4.5 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAP61358.1 - 1.4e-13 50.4 12.5 1.6e-07 30.9 0.2 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 OAP61358.1 - 3.6e-06 26.2 6.7 0.48 10.6 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 OAP61358.1 - 0.015 15.3 0.6 2e+02 2.9 0.0 5.5 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 OAP61358.1 - 0.045 13.8 0.9 44 4.5 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich repeat zf-C2HC5 PF06221.8 OAP61359.1 - 2.9e-21 74.9 6.3 4.4e-21 74.3 4.3 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Hexokinase_2 PF03727.11 OAP61360.1 - 1.7e-68 230.4 0.1 3.7e-68 229.3 0.1 1.6 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 OAP61360.1 - 4.3e-67 225.4 0.9 5.4e-67 225.1 0.1 1.5 2 0 0 2 2 2 1 Hexokinase Kinesin PF00225.18 OAP61360.1 - 0.14 10.8 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain 4HBT PF03061.17 OAP61362.1 - 0.012 15.7 0.2 0.32 11.1 0.0 2.6 2 1 0 2 2 2 0 Thioesterase superfamily DASH_Hsk3 PF08227.6 OAP61363.1 - 4.9e-22 77.8 2.8 7e-22 77.3 1.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Mating_C PF12737.2 OAP61363.1 - 0.0064 15.4 0.8 0.0071 15.2 0.5 1.0 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 FlxA PF14282.1 OAP61363.1 - 0.022 14.6 0.2 0.032 14.1 0.2 1.2 1 0 0 1 1 1 0 FlxA-like protein FTA4 PF13093.1 OAP61363.1 - 0.1 11.9 0.3 0.13 11.7 0.2 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RIC3 PF15361.1 OAP61363.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF446 PF04287.7 OAP61363.1 - 0.11 12.2 0.1 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA pseudouridine synthase C GST_C_2 PF13410.1 OAP61363.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NmrA PF05368.8 OAP61364.1 - 3.7e-12 46.0 0.0 4.6e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP61364.1 - 2e-06 27.9 0.0 3.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 OAP61364.1 - 0.00098 19.4 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.7 OAP61365.1 - 9.2e-31 105.8 0.4 1.9e-30 104.8 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP61365.1 - 4.2e-24 84.5 5.2 1e-23 83.3 1.6 2.4 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP61365.1 - 2.6e-08 34.7 1.9 7e-08 33.4 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 OAP61365.1 - 0.00096 19.1 0.8 0.0032 17.4 0.4 1.9 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 OAP61365.1 - 0.0015 18.6 0.4 0.0035 17.4 0.3 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MTS PF05175.9 OAP61365.1 - 0.0016 17.8 0.4 0.003 16.9 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAP61365.1 - 0.002 18.1 0.8 0.035 14.1 0.1 2.3 1 1 1 2 2 2 1 Methyltransferase domain TP_methylase PF00590.15 OAP61365.1 - 0.0081 15.8 0.7 0.22 11.2 0.2 2.7 2 1 1 3 3 3 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Methyltransf_31 PF13847.1 OAP61365.1 - 0.04 13.5 0.1 0.11 12.0 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61365.1 - 0.055 14.0 0.3 6.9 7.3 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.13 OAP61365.1 - 0.32 10.6 2.3 0.6 9.7 1.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 OAP61366.1 - 1.2e-67 228.4 0.0 1.5e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cas_Cas5d PF09704.5 OAP61366.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) Alpha-amylase PF00128.19 OAP61367.1 - 9.3e-33 113.9 0.2 2.1e-32 112.7 0.2 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.5 OAP61367.1 - 4.4e-05 23.2 0.0 8.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.11 OAP61367.1 - 6.3e-05 20.9 0.2 0.0034 15.2 0.0 2.8 2 1 1 3 3 3 1 Glycosyl hydrolase family 70 SAM_PNT PF02198.11 OAP61367.1 - 0.38 10.5 2.6 0.31 10.8 0.2 2.0 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain 4HBT PF03061.17 OAP61368.1 - 4.9e-08 32.9 0.3 7.8e-08 32.3 0.2 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 OAP61368.1 - 0.0043 16.8 0.9 0.011 15.5 0.2 1.7 1 1 1 2 2 2 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.14 OAP61368.1 - 0.11 11.8 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 MaoC like domain p450 PF00067.17 OAP61369.1 - 6.9e-49 166.6 0.0 1.2e-48 165.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 CHAT PF12770.2 OAP61370.1 - 2.1e-36 125.5 0.2 4e-36 124.6 0.1 1.5 1 0 0 1 1 1 1 CHAT domain Abhydrolase_3 PF07859.8 OAP61371.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP61371.1 - 0.0022 17.8 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP61371.1 - 0.004 16.9 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP61371.1 - 0.0066 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 OAP61372.1 - 3.2e-38 131.3 42.7 3.2e-38 131.3 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP61372.1 - 1.1e-10 40.6 9.9 1.1e-10 40.6 6.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Imm2 PF14426.1 OAP61373.1 - 0.039 13.9 0.1 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm2 Zn_clus PF00172.13 OAP61373.1 - 3.6 7.5 14.4 22 5.0 10.0 2.4 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.1 OAP61374.1 - 5.1e-13 48.8 1.9 1.1e-12 47.8 0.8 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_1 PF00175.16 OAP61374.1 - 2.8e-09 37.4 0.0 6.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_2 PF00890.19 OAP61374.1 - 6.4e-08 31.8 5.0 6.6e-07 28.5 3.5 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_6 PF00970.19 OAP61374.1 - 1.1e-07 31.8 0.0 2.7e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DAO PF01266.19 OAP61374.1 - 5.5e-07 28.8 1.3 1.4e-06 27.5 0.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 OAP61374.1 - 0.00028 20.0 0.6 0.00028 20.0 0.4 2.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 OAP61374.1 - 0.00078 18.5 0.3 0.0014 17.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 OAP61374.1 - 0.0015 17.6 0.9 0.0027 16.8 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP61374.1 - 0.011 15.6 0.6 0.02 14.7 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP61374.1 - 0.02 14.0 1.1 0.032 13.3 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP61374.1 - 0.036 12.5 0.4 0.43 8.9 0.8 1.9 2 0 0 2 2 2 0 HI0933-like protein Tn7_Tnp_TnsA_C PF08721.6 OAP61374.1 - 0.063 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 TnsA endonuclease C terminal GIDA PF01134.17 OAP61374.1 - 0.28 10.0 1.4 0.43 9.3 1.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2207 PF09972.4 OAP61375.1 - 1.2 7.6 2.6 1.7 7.1 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Catalase PF00199.14 OAP61376.1 - 7e-156 518.7 0.2 9.2e-156 518.3 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAP61376.1 - 3.5e-19 68.4 0.0 6.3e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Autophagy_N PF03986.8 OAP61377.1 - 2.6e-44 150.5 0.3 5.5e-44 149.4 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 OAP61377.1 - 2.8e-22 78.6 1.0 5.3e-22 77.7 0.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 OAP61377.1 - 1.6e-14 52.6 0.4 2.6e-14 51.9 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal ATG2_CAD PF13329.1 OAP61377.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF1777 PF08648.7 OAP61378.1 - 7.5e-13 48.6 44.9 7.5e-13 48.6 31.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 OAP61378.1 - 0.00097 17.7 25.7 0.0015 17.1 17.8 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 p450 PF00067.17 OAP61380.1 - 5.4e-47 160.3 0.0 7.3e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4019 PF13211.1 OAP61380.1 - 0.004 17.3 0.5 0.0076 16.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4019) Methyltransf_23 PF13489.1 OAP61381.1 - 4.7e-14 52.4 0.0 7.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP61381.1 - 5.9e-14 51.9 0.0 8.2e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP61381.1 - 5e-11 42.9 0.0 9.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61381.1 - 2.5e-10 40.9 0.0 5.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP61381.1 - 9.2e-10 38.0 0.0 4.8e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 OAP61381.1 - 7.8e-09 35.9 0.0 1.6e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP61381.1 - 1e-08 35.4 0.0 2.3e-08 34.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 OAP61381.1 - 4.6e-05 23.0 0.0 0.00016 21.2 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 OAP61381.1 - 0.00025 21.0 0.0 0.0004 20.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP61381.1 - 0.00053 19.4 0.0 0.0017 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 OAP61381.1 - 0.00071 19.6 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase FmrO PF07091.6 OAP61381.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF4593 PF15263.1 OAP61382.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) DUF2153 PF09921.4 OAP61382.1 - 0.021 14.4 0.3 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Cyclin_N PF00134.18 OAP61384.1 - 2.9e-06 26.8 0.0 2.4e-05 23.9 0.0 2.2 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 OAP61384.1 - 0.0017 18.1 0.0 0.5 10.2 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat PNGaseA PF12222.3 OAP61385.1 - 4.2e-125 417.9 11.1 2.7e-124 415.2 7.7 1.8 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Elong_Iki1 PF10483.4 OAP61386.1 - 8.2e-65 218.9 0.0 1.2e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.1 OAP61387.1 - 3e-29 100.4 1.2 3e-29 100.4 0.8 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 OAP61387.1 - 1.1e-15 57.0 0.0 1.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 OAP61387.1 - 0.12 12.1 1.7 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PilJ PF13675.1 OAP61387.1 - 0.32 11.3 2.3 1.3 9.4 0.1 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Nsp1_C PF05064.8 OAP61387.1 - 0.96 9.1 3.6 2.9 7.5 0.3 2.9 2 1 2 4 4 4 0 Nsp1-like C-terminal region DUF706 PF05153.10 OAP61388.1 - 4.4e-129 429.2 1.5 5.4e-129 428.8 1.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 OAP61388.1 - 0.07 13.1 0.5 0.99 9.4 0.0 2.5 3 0 0 3 3 3 0 HD domain RF-1 PF00472.15 OAP61388.1 - 0.085 12.6 0.6 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 RF-1 domain Aldo_ket_red PF00248.16 OAP61389.1 - 5.5e-48 163.2 0.0 6.5e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.17 OAP61390.1 - 2.5e-25 89.3 0.5 6.5e-25 87.9 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP61390.1 - 1.6e-05 24.6 0.1 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 OAP61390.1 - 0.021 14.6 0.1 0.079 12.7 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 OAP61390.1 - 0.076 13.2 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Glyco_transf_8 PF01501.15 OAP61393.1 - 1.7e-26 93.1 0.2 2.6e-26 92.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 HAD_2 PF13419.1 OAP61393.1 - 1.2e-18 67.9 0.3 3.9e-18 66.2 0.0 1.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP61393.1 - 1.1e-06 29.2 0.0 9.2e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP61393.1 - 9.8e-05 21.9 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Nucleotid_trans PF03407.11 OAP61393.1 - 0.0053 16.5 2.8 0.011 15.4 1.9 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 OAP61393.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative CH PF00307.26 OAP61394.1 - 1.5e-37 127.9 0.0 1e-18 67.3 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 OAP61394.1 - 2.5e-12 46.2 0.3 4.7e-07 29.3 0.0 3.7 3 1 1 4 4 4 2 CAMSAP CH domain EF-hand_6 PF13405.1 OAP61394.1 - 1.7e-05 24.3 0.1 8e-05 22.2 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 OAP61394.1 - 0.00022 20.3 0.1 0.00079 18.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 OAP61394.1 - 0.0009 18.8 0.1 0.0034 16.9 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EFhand_Ca_insen PF08726.5 OAP61394.1 - 0.0021 17.9 0.8 0.0098 15.8 0.1 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1943 PF09172.6 OAP61394.1 - 0.004 16.0 0.2 0.0069 15.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) EF-hand_7 PF13499.1 OAP61394.1 - 0.014 15.4 0.1 0.014 15.4 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 OAP61394.1 - 0.028 13.7 0.0 0.074 12.4 0.0 1.8 1 0 0 1 1 1 0 EF hand Spectrin PF00435.16 OAP61394.1 - 0.082 13.2 6.0 7.7 6.8 0.0 2.8 2 0 0 2 2 2 0 Spectrin repeat AMP-binding PF00501.23 OAP61395.1 - 1.6e-65 221.1 0.0 2e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP61395.1 - 1.4e-13 51.5 0.0 3.3e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_6 PF00970.19 OAP61396.1 - 1e-13 51.2 0.0 2.6e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAP61396.1 - 1.4e-07 32.0 0.0 0.0014 19.2 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Pyr_redox_2 PF07992.9 OAP61397.1 - 1.9e-21 76.8 3.9 1.8e-19 70.4 2.7 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP61397.1 - 5.6e-20 71.5 4.6 4.2e-17 62.3 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 OAP61397.1 - 8.7e-16 57.9 0.0 2.1e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GIDA PF01134.17 OAP61397.1 - 1.7e-09 37.0 3.8 3.2e-06 26.2 0.1 2.6 2 1 1 3 3 3 2 Glucose inhibited division protein A 3HCDH_N PF02737.13 OAP61397.1 - 8.2e-07 28.8 2.6 0.003 17.2 0.1 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 OAP61397.1 - 1.1e-06 28.9 4.0 0.00019 21.5 0.6 3.4 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 OAP61397.1 - 4.2e-06 26.9 1.5 0.034 14.3 0.0 3.0 2 1 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.19 OAP61397.1 - 5.2e-06 25.6 7.2 0.038 12.8 0.2 3.6 3 1 0 3 3 3 3 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP61397.1 - 2.5e-05 23.4 2.2 0.02 13.8 0.1 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP61397.1 - 4.6e-05 22.4 3.6 0.036 12.9 0.1 3.7 4 0 0 4 4 4 2 FAD binding domain 2-Hacid_dh_C PF02826.14 OAP61397.1 - 0.00011 21.3 0.5 0.17 11.0 0.0 3.8 4 0 0 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 OAP61397.1 - 0.00031 19.9 0.3 0.0095 15.0 0.0 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 OAP61397.1 - 0.00041 19.3 0.4 0.0023 16.9 0.0 2.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 OAP61397.1 - 0.00066 18.2 7.1 0.14 10.5 0.0 3.5 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.14 OAP61397.1 - 0.0013 17.8 1.8 0.12 11.4 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 OAP61397.1 - 0.003 16.6 3.0 0.18 10.8 0.4 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase TrkA_N PF02254.13 OAP61397.1 - 0.0033 17.3 0.6 3.8 7.5 0.1 3.0 2 0 0 2 2 2 2 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 OAP61397.1 - 0.0055 16.0 0.2 0.75 9.1 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 OAP61397.1 - 0.0095 15.5 4.2 0.15 11.6 0.0 3.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 OAP61397.1 - 0.0095 16.2 0.1 2.8 8.2 0.0 2.7 2 0 0 2 2 2 1 XdhC Rossmann domain CPSase_L_chain PF00289.17 OAP61397.1 - 0.015 15.4 0.1 9.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain F420_oxidored PF03807.12 OAP61397.1 - 0.098 13.0 1.0 9.5 6.7 0.0 3.1 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 OAP61397.1 - 0.11 12.2 3.1 15 5.3 0.0 3.5 4 0 0 4 4 4 0 ThiF family MutL PF13941.1 OAP61399.1 - 0.0072 14.6 0.1 0.013 13.8 0.1 1.3 1 0 0 1 1 1 1 MutL protein EutA PF06277.6 OAP61399.1 - 0.024 13.2 0.4 0.27 9.7 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA Hydantoinase_A PF01968.13 OAP61399.1 - 0.033 13.3 0.4 0.058 12.4 0.3 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase SrfB PF07520.6 OAP61399.1 - 0.1 10.0 0.0 0.15 9.4 0.0 1.1 1 0 0 1 1 1 0 Virulence factor SrfB Ppx-GppA PF02541.11 OAP61399.1 - 0.2 10.8 0.1 0.36 9.9 0.1 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family MreB_Mbl PF06723.8 OAP61399.1 - 0.25 9.8 0.5 0.58 8.7 0.3 1.5 1 0 0 1 1 1 0 MreB/Mbl protein AA_permease_2 PF13520.1 OAP61401.1 - 1.7e-65 221.2 38.0 2.4e-65 220.7 26.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP61401.1 - 1.3e-27 96.2 24.4 1.3e-27 96.2 16.9 2.1 2 0 0 2 2 2 2 Amino acid permease NADHdeh_related PF10125.4 OAP61401.1 - 0.0014 17.8 4.0 0.0034 16.5 2.8 1.6 1 0 0 1 1 1 1 NADH dehydrogenase I, subunit N related protein GFO_IDH_MocA PF01408.17 OAP61403.1 - 1e-23 84.1 0.0 1.7e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP61403.1 - 2.6e-15 56.2 0.0 4.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 OAP61403.1 - 0.0059 16.9 0.1 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain LolB PF03550.9 OAP61403.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Cyclin_N PF00134.18 OAP61404.1 - 5.6e-07 29.1 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain UQ_con PF00179.21 OAP61405.1 - 1.2e-41 141.4 0.0 1.6e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 OAP61405.1 - 9.9e-05 21.8 0.1 0.00018 21.0 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 OAP61405.1 - 0.0028 17.4 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAP61405.1 - 0.061 13.2 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 OAP61405.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain AAA PF00004.24 OAP61406.1 - 5.2e-41 139.9 0.0 9.9e-41 139.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP61406.1 - 5e-07 29.9 0.1 0.00019 21.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 OAP61406.1 - 4.4e-06 26.7 0.0 9.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 OAP61406.1 - 1.1e-05 24.4 0.0 1.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 OAP61406.1 - 4.6e-05 23.1 0.1 0.00013 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAP61406.1 - 0.00024 21.1 0.3 0.00079 19.4 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.7 OAP61406.1 - 0.00029 19.9 0.0 0.00052 19.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 OAP61406.1 - 0.0017 18.3 0.1 0.0045 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAP61406.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAP61406.1 - 0.0032 18.2 0.1 0.01 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 OAP61406.1 - 0.0058 16.3 0.1 0.35 10.5 0.1 2.6 1 1 1 2 2 2 1 NACHT domain IstB_IS21 PF01695.12 OAP61406.1 - 0.0058 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 OAP61406.1 - 0.006 16.1 0.0 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 OAP61406.1 - 0.006 16.2 0.3 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 OAP61406.1 - 0.0087 15.1 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 OAP61406.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAP61406.1 - 0.011 16.0 0.1 0.022 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 OAP61406.1 - 0.016 13.9 0.1 0.039 12.6 0.0 1.5 1 1 0 1 1 1 0 TIP49 C-terminus KaiC PF06745.8 OAP61406.1 - 0.021 13.9 0.2 0.46 9.5 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.1 OAP61406.1 - 0.024 14.0 1.5 0.26 10.6 0.3 2.3 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 OAP61406.1 - 0.038 12.8 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 OAP61406.1 - 0.04 14.1 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 OAP61406.1 - 0.041 13.1 0.3 0.21 10.7 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 OAP61406.1 - 0.052 12.7 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 OAP61406.1 - 0.057 12.9 0.2 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 OAP61406.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TRAM_LAG1_CLN8 PF03798.11 OAP61407.1 - 1.3e-44 152.1 20.9 1.3e-44 152.1 14.5 2.0 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 OAP61407.1 - 1.3e-18 66.1 0.2 3.5e-18 64.8 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein FAM177 PF14774.1 OAP61407.1 - 0.055 13.3 2.3 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 FAM177 family WD40 PF00400.27 OAP61408.1 - 2.2e-34 116.0 16.2 1.2e-11 44.0 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 OAP61408.1 - 0.0021 16.2 0.9 0.083 11.0 0.4 2.4 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 OAP61408.1 - 0.0026 16.4 0.0 0.045 12.3 0.0 2.2 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) GAS PF13851.1 OAP61409.1 - 0.0042 16.3 3.3 0.0065 15.6 2.3 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding PEP-utilisers_N PF05524.8 OAP61409.1 - 0.073 12.8 4.7 4.2 7.1 0.9 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF2570 PF10828.3 OAP61409.1 - 0.15 11.6 4.5 0.28 10.7 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Tropomyosin_1 PF12718.2 OAP61409.1 - 0.19 11.5 2.3 0.37 10.6 1.6 1.4 1 0 0 1 1 1 0 Tropomyosin like Mod_r PF07200.8 OAP61409.1 - 0.24 11.3 3.4 0.47 10.3 2.3 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF972 PF06156.8 OAP61409.1 - 0.62 10.4 2.3 3 8.2 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CCDC-167 PF15188.1 OAP61409.1 - 0.72 9.8 4.8 3.3 7.7 0.2 2.5 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 CPSase_L_D2 PF02786.12 OAP61410.1 - 1e-75 253.6 0.0 1.9e-75 252.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 OAP61410.1 - 6.7e-38 128.9 0.0 1.7e-37 127.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 OAP61410.1 - 1.8e-35 121.3 0.0 5.1e-35 119.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 OAP61410.1 - 1e-20 74.2 0.0 4.1e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 OAP61410.1 - 9.8e-15 53.9 1.3 2.3e-14 52.7 0.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 OAP61410.1 - 1.3e-14 53.6 0.0 2.3e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAP61410.1 - 2e-09 37.1 0.0 4.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 OAP61410.1 - 1.8e-07 30.6 0.0 3.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 OAP61410.1 - 3.9e-06 26.4 0.7 8.7e-05 22.1 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 OAP61410.1 - 3e-05 23.5 0.0 0.0005 19.6 0.0 2.4 3 0 0 3 3 3 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 OAP61410.1 - 6.9e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 OAP61410.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 OAP61410.1 - 0.083 11.9 0.1 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Toxin_59 PF15537.1 OAP61410.1 - 0.11 12.5 0.0 0.46 10.5 0.0 2.1 1 0 0 1 1 1 0 Putative toxin 59 TAF4 PF05236.9 OAP61412.1 - 3.6 6.7 10.3 15 4.7 0.1 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family MARVEL PF01284.18 OAP61413.1 - 0.00044 20.0 8.6 0.0007 19.4 6.0 1.3 1 1 0 1 1 1 1 Membrane-associating domain PgpA PF04608.8 OAP61413.1 - 0.16 11.7 5.9 0.3 10.8 3.4 1.7 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A adh_short_C2 PF13561.1 OAP61414.1 - 1.5e-29 103.4 0.1 2e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP61414.1 - 6.4e-24 84.7 0.5 9.2e-24 84.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61414.1 - 2.9e-13 49.8 0.5 4.5e-13 49.2 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP61414.1 - 0.00021 20.7 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1752 PF08550.5 OAP61415.1 - 0.036 13.6 1.2 0.11 12.0 0.8 1.9 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1752) BSP_II PF05432.6 OAP61415.1 - 0.054 12.7 10.8 0.11 11.7 7.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sec62 PF03839.11 OAP61415.1 - 5.3 6.3 6.1 8.6 5.7 4.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 PHD PF00628.24 OAP61416.1 - 2.2e-09 36.8 6.1 5.3e-09 35.6 4.2 1.7 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAP61416.1 - 0.0089 15.3 2.8 0.015 14.5 1.9 1.4 1 0 0 1 1 1 1 PHD-finger DUF3425 PF11905.3 OAP61417.1 - 1.7e-21 76.5 7.1 3.2e-21 75.6 1.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP61417.1 - 0.0057 16.5 6.9 0.0099 15.8 4.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP61417.1 - 0.039 13.7 6.7 0.073 12.9 4.6 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Ras PF00071.17 OAP61418.1 - 5.8e-24 84.3 0.0 6.9e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP61418.1 - 1e-06 29.2 0.0 2.1e-06 28.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 OAP61418.1 - 0.022 14.0 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Carboxyl_trans PF01039.17 OAP61419.1 - 2.3e-145 484.7 0.1 3.2e-145 484.2 0.1 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain BAF1_ABF1 PF04684.8 OAP61419.1 - 0.17 10.7 0.1 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HET PF06985.6 OAP61420.1 - 2.4e-06 27.7 0.0 3.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.18 OAP61421.1 - 2.2e-07 30.8 0.1 3.6e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 OAP61421.1 - 1.2e-06 27.8 0.0 2.8e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 OAP61421.1 - 0.0021 17.5 0.1 0.0053 16.2 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF258 PF03193.11 OAP61421.1 - 0.0057 15.8 0.5 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 OAP61421.1 - 0.014 15.2 1.5 0.82 9.4 0.0 2.4 1 1 1 2 2 2 0 Dynamin family AAA_33 PF13671.1 OAP61421.1 - 0.015 15.1 0.1 0.048 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAP61421.1 - 0.016 15.5 0.0 0.084 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 OAP61421.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Peptidase_S9 PF00326.16 OAP61421.1 - 0.023 13.9 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Viral_helicase1 PF01443.13 OAP61421.1 - 0.033 13.6 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 OAP61421.1 - 0.039 14.4 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 OAP61421.1 - 0.046 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 OAP61421.1 - 0.049 13.1 0.1 0.14 11.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 OAP61421.1 - 0.068 12.9 0.3 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF815 PF05673.8 OAP61421.1 - 0.077 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 OAP61421.1 - 0.078 13.7 0.1 0.16 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 OAP61421.1 - 0.1 11.4 0.1 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_P4 PF11602.3 OAP61421.1 - 0.1 11.5 0.0 0.78 8.6 0.0 2.0 2 0 0 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 Septin PF00735.13 OAP61421.1 - 0.14 11.1 0.0 0.3 10.0 0.0 1.5 1 0 0 1 1 1 0 Septin Cupin_2 PF07883.6 OAP61422.1 - 6e-07 28.8 0.0 9.9e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 OAP61422.1 - 0.078 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pro_isomerase PF00160.16 OAP61424.1 - 1.8e-52 177.6 0.1 2.1e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NAD_binding_6 PF08030.7 OAP61425.1 - 2.8e-20 72.7 0.0 1.8e-19 70.1 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAP61425.1 - 3.3e-17 62.7 11.5 3.3e-17 62.7 8.0 2.7 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 OAP61425.1 - 1.8e-14 53.5 0.0 3.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 OAP61425.1 - 6.3e-06 26.7 0.0 0.049 14.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain POP1 PF06978.6 OAP61426.1 - 1.8e-59 200.5 20.3 1.8e-59 200.5 14.1 2.8 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 OAP61426.1 - 4e-25 87.4 1.2 1e-24 86.1 0.3 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain Fungal_trans_2 PF11951.3 OAP61427.1 - 9e-13 47.5 0.0 1.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.16 OAP61428.1 - 4.8e-06 26.4 12.3 4.8e-06 26.4 5.8 2.0 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 OAP61428.1 - 0.013 15.3 12.6 0.032 14.0 4.7 2.2 1 1 1 2 2 2 0 Basic region leucine zipper TMCO5 PF14992.1 OAP61428.1 - 0.019 14.0 0.6 0.029 13.4 0.4 1.2 1 0 0 1 1 1 0 TMCO5 family FlxA PF14282.1 OAP61428.1 - 0.046 13.6 1.2 2.7 8.0 1.2 2.5 1 1 1 2 2 2 0 FlxA-like protein CENP-F_leu_zip PF10473.4 OAP61428.1 - 0.053 13.3 2.3 0.076 12.8 1.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4094 PF13334.1 OAP61428.1 - 0.085 13.2 1.0 0.14 12.5 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Vac_Fusion PF02346.11 OAP61428.1 - 0.13 11.6 0.5 0.22 10.9 0.4 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein IncA PF04156.9 OAP61428.1 - 1.8 8.1 5.7 2.7 7.5 4.0 1.2 1 0 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 OAP61428.1 - 4.3 7.7 9.5 9.9 6.5 6.6 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor Redoxin PF08534.5 OAP61429.1 - 1.5e-33 115.4 0.0 1.7e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAP61429.1 - 9.3e-13 47.9 0.0 1.3e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 OAP61430.1 - 7e-43 145.8 1.5 8.8e-43 145.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 OAP61430.1 - 1e-05 25.7 0.1 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 OAP61430.1 - 0.00031 21.0 0.1 0.00075 19.8 0.1 1.8 1 1 0 1 1 1 1 SnoaL-like domain DUF3132 PF11330.3 OAP61430.1 - 0.097 12.5 0.3 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) PknH_C PF14032.1 OAP61430.1 - 2.3 7.7 4.6 1.7 8.1 0.1 2.4 3 0 0 3 3 3 0 PknH-like extracellular domain Fasciclin PF02469.17 OAP61431.1 - 8.7e-45 151.8 0.0 3.5e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Pkinase PF00069.20 OAP61432.1 - 1.6e-71 240.4 0.0 2.7e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61432.1 - 2.1e-36 125.3 0.0 1.2e-33 116.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 OAP61432.1 - 0.00039 20.2 0.0 0.013 15.2 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 OAP61432.1 - 0.0056 15.7 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 OAP61432.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 OAP61432.1 - 0.04 12.8 0.0 0.081 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like HET PF06985.6 OAP61433.1 - 6.5e-24 84.6 0.0 1.8e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMO-like PF00743.14 OAP61434.1 - 3.8e-36 124.3 0.0 4.7e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAP61434.1 - 2.5e-17 63.6 0.0 9e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP61434.1 - 5.7e-08 32.0 0.0 1.3e-05 24.3 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP61434.1 - 1.7e-07 31.3 0.0 7.1e-05 22.7 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP61434.1 - 3.2e-06 27.0 0.0 2.9e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAP61434.1 - 0.00016 21.6 0.0 0.0004 20.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP61434.1 - 0.0085 15.0 0.2 0.27 10.1 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP61434.1 - 0.16 12.3 0.2 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1690 PF07956.6 OAP61435.1 - 2.7e-26 92.2 10.7 1.6e-23 83.2 7.4 2.1 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) MutS_II PF05188.12 OAP61435.1 - 0.0031 17.5 0.3 0.0069 16.4 0.1 1.6 1 1 0 1 1 1 1 MutS domain II Rootletin PF15035.1 OAP61435.1 - 0.0071 16.3 1.0 0.0071 16.3 0.7 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Tup_N PF08581.5 OAP61435.1 - 0.27 11.4 7.6 0.82 9.9 0.2 3.1 2 1 1 3 3 3 0 Tup N-terminal Lzipper-MIP1 PF14389.1 OAP61435.1 - 2.8 8.1 9.1 0.61 10.2 1.9 2.3 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Apolipoprotein PF01442.13 OAP61435.1 - 3 7.2 9.7 29 4.1 6.7 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Acetyltransf_1 PF00583.19 OAP61436.1 - 5.1e-09 36.0 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP61436.1 - 2.8e-05 24.1 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP61436.1 - 0.002 18.2 0.0 0.0042 17.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP61436.1 - 0.0024 17.6 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Methyltransf_2 PF00891.13 OAP61438.1 - 1.1e-32 113.1 0.0 1.9e-32 112.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 OAP61438.1 - 0.018 14.7 0.0 0.044 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain HTH_27 PF13463.1 OAP61438.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Methyltransf_23 PF13489.1 OAP61439.1 - 9.2e-21 74.2 0.1 5.8e-20 71.6 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP61439.1 - 7e-13 48.4 0.0 3.2e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP61439.1 - 9.2e-11 42.0 0.0 2.8e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61439.1 - 8.1e-10 39.2 0.1 6.4e-09 36.3 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP61439.1 - 7.3e-09 35.9 0.0 4.2e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP61439.1 - 2.3e-07 31.1 0.0 1.6e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 OAP61439.1 - 1.3e-05 24.4 0.0 2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 OAP61439.1 - 2.2e-05 24.4 0.0 0.00012 22.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAP61439.1 - 0.00044 19.6 0.0 0.0017 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 OAP61439.1 - 0.0021 17.1 0.0 0.0079 15.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 OAP61439.1 - 0.029 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 OAP61439.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 OAP61439.1 - 0.09 11.8 0.0 0.24 10.4 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family SNF5 PF04855.7 OAP61439.1 - 0.093 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 CMAS PF02353.15 OAP61439.1 - 0.097 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 OAP61439.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_S28 PF05577.7 OAP61440.1 - 3e-33 115.0 0.0 4.5e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 OAP61440.1 - 2.6e-05 23.5 0.0 0.0028 16.8 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAP61440.1 - 0.0034 17.3 0.3 0.0093 15.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family GDPD PF03009.12 OAP61441.1 - 1.7e-13 50.6 0.0 2.1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CorA PF01544.13 OAP61442.1 - 0.0036 16.3 1.9 0.0039 16.2 0.3 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SLAC1 PF03595.12 OAP61442.1 - 0.0085 14.7 3.2 0.012 14.2 2.2 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4149 PF13664.1 OAP61442.1 - 0.057 13.4 2.4 0.11 12.5 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Sugar_tr PF00083.19 OAP61443.1 - 8.9e-45 153.0 14.3 1.4e-44 152.4 9.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61443.1 - 3.4e-20 72.0 19.8 7e-20 71.0 13.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CMAS PF02353.15 OAP61444.1 - 2.4e-60 203.9 0.0 3e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 OAP61444.1 - 8.2e-12 45.1 0.0 1.6e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP61444.1 - 0.00076 19.9 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 OAP61444.1 - 0.0047 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 OAP61444.1 - 0.016 15.6 0.1 0.099 13.1 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAP61444.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61444.1 - 0.032 14.8 0.0 0.14 12.7 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain EXS PF03124.9 OAP61445.1 - 3.6e-104 348.5 8.2 4.1e-104 348.3 5.6 1.0 1 0 0 1 1 1 1 EXS family Sugar_tr PF00083.19 OAP61446.1 - 9.6e-39 133.1 34.2 8.9e-22 77.2 7.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP61446.1 - 7.1e-24 84.1 33.8 2.9e-12 45.9 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 OAP61447.1 - 7.3e-25 88.2 0.0 1.1e-24 87.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HD PF01966.17 OAP61447.1 - 5.8e-08 32.7 0.0 8.6e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 HD domain 2OG-FeII_Oxy_5 PF13759.1 OAP61447.1 - 0.00047 20.4 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase HDOD PF08668.7 OAP61447.1 - 0.0049 16.1 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 HDOD domain HD_4 PF13328.1 OAP61447.1 - 0.007 16.0 0.1 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 HD domain Peptidase_A25 PF03418.9 OAP61447.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Germination protease CRAL_TRIO PF00650.15 OAP61448.1 - 3.4e-19 68.9 0.0 4.3e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAP61448.1 - 1.2e-07 31.6 0.0 2.9e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ribosomal_S16 PF00886.14 OAP61449.1 - 1.8e-22 78.8 0.0 3.3e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 OAP61450.1 - 6.2e-37 126.7 0.0 7.6e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Glyco_trans_1_4 PF13692.1 OAP61450.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 DnaJ PF00226.26 OAP61451.1 - 9.1e-28 95.7 3.6 1.5e-27 95.1 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAP61451.1 - 9.1e-24 83.1 0.7 3.2e-21 74.9 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain Fungal_trans_2 PF11951.3 OAP61452.1 - 9.1e-06 24.5 0.4 1.4e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1620 PF07774.8 OAP61453.1 - 3.9e-68 228.9 0.0 6e-68 228.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 OAP61453.1 - 1.9e-15 56.9 16.3 3.1e-09 36.6 2.8 3.8 2 2 1 4 4 4 2 PQQ-like domain PQQ PF01011.16 OAP61453.1 - 0.00074 18.9 4.2 9.5 5.9 0.0 5.3 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.1 OAP61453.1 - 0.001 19.2 14.8 0.55 10.5 0.1 6.6 7 0 0 7 7 7 2 PQQ-like domain PFU PF09070.6 OAP61454.1 - 1.5e-42 144.2 0.3 2.8e-42 143.3 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 OAP61454.1 - 1.1e-32 110.6 14.3 2.1e-08 33.7 0.0 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat PUL PF08324.6 OAP61454.1 - 1e-27 96.6 0.0 1.5e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 OAP61454.1 - 0.029 14.1 0.0 3.7 7.3 0.0 3.2 1 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Zn_clus PF00172.13 OAP61455.1 - 2.7e-07 30.3 7.2 6.2e-07 29.2 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 OAP61456.1 - 5.1e-13 49.5 1.0 1.5e-12 48.0 0.4 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family ERG2_Sigma1R PF04622.7 OAP61457.1 - 1.8e-76 256.1 1.4 1.4e-75 253.2 1.0 1.9 1 1 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PepSY_TM PF03929.11 OAP61457.1 - 7.2 7.2 7.7 5.2 7.6 3.5 2.2 2 0 0 2 2 2 0 PepSY-associated TM helix 3Beta_HSD PF01073.14 OAP61458.1 - 1.3e-29 102.8 0.0 5.3e-29 100.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP61458.1 - 3e-17 62.8 0.0 8.5e-17 61.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP61458.1 - 9.5e-10 37.8 0.0 3.4e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 OAP61458.1 - 5.8e-07 29.5 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61458.1 - 1.4e-06 28.1 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP61458.1 - 4.6e-06 25.7 0.0 1.7e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAP61458.1 - 9.5e-06 25.7 0.0 4.6e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 OAP61458.1 - 5.8e-05 22.1 0.0 0.0014 17.5 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain DUF3712 PF12505.3 OAP61459.1 - 5.8e-20 71.5 0.0 1.3e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) CoA_transf_3 PF02515.12 OAP61461.1 - 3.1e-43 147.2 0.2 4.5e-38 130.4 0.1 2.3 2 0 0 2 2 2 2 CoA-transferase family III An_peroxidase PF03098.10 OAP61462.1 - 1.8e-92 310.4 0.0 3.9e-90 302.7 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 OAP61462.1 - 0.00019 20.0 0.0 0.00042 18.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.4 OAP61463.1 - 3.9e-102 341.3 2.1 7.1e-102 340.4 1.5 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DPM3 PF08285.6 OAP61464.1 - 0.12 12.2 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4203 PF13886.1 OAP61465.1 - 8.9e-37 126.5 27.0 1.2e-36 126.2 18.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Pept_tRNA_hydro PF01195.14 OAP61467.1 - 1.1e-30 106.4 0.0 1.7e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase MFS_1 PF07690.11 OAP61468.1 - 3.7e-24 85.0 28.7 5.9e-24 84.4 19.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_15 PF01793.11 OAP61469.1 - 9.7e-134 445.4 8.5 1.2e-133 445.2 5.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Voldacs PF03517.8 OAP61470.1 - 2.2e-29 102.0 0.9 3.3e-29 101.4 0.0 1.7 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Spc97_Spc98 PF04130.8 OAP61471.1 - 3.9e-54 183.9 6.1 5.1e-54 183.5 4.2 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Abhydrolase_2 PF02230.11 OAP61473.1 - 1.2e-14 54.2 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 OAP61473.1 - 3e-06 27.0 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP61473.1 - 4.7e-05 23.3 0.9 0.00017 21.5 0.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAP61473.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 0 Putative esterase DUF3759 PF12585.3 OAP61474.1 - 4.9e-41 138.5 7.2 5.9e-41 138.2 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) XRCC4 PF06632.7 OAP61475.1 - 2.1e-14 53.1 13.1 2.8e-14 52.7 9.1 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 V_ATPase_I PF01496.14 OAP61475.1 - 0.094 10.5 3.6 0.13 10.0 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 OAP61475.1 - 0.098 11.0 4.7 0.16 10.3 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NPV_P10 PF05531.7 OAP61475.1 - 0.52 10.6 7.0 0.38 11.0 2.5 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AP_endonuc_2 PF01261.19 OAP61477.1 - 1.1e-26 93.5 0.1 1.8e-26 92.7 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Glyco_hydro_43 PF04616.9 OAP61478.1 - 9.8e-23 80.6 0.1 1.3e-22 80.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 OAP61478.1 - 0.0094 15.3 0.0 0.1 11.9 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Alk_phosphatase PF00245.15 OAP61479.1 - 2.1e-70 237.5 0.2 1.8e-69 234.4 0.2 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 OAP61479.1 - 1.4e-08 34.5 0.1 2.4e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 OAP61479.1 - 1.5e-07 30.9 0.3 5.3e-07 29.1 0.2 1.8 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 OAP61479.1 - 0.0036 15.7 0.2 0.0053 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 OAP61479.1 - 0.056 12.8 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily HET PF06985.6 OAP61481.1 - 0.00015 21.9 0.4 0.0012 19.0 0.0 2.4 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF1479 PF07350.7 OAP61482.1 - 0.27 9.6 0.1 0.43 9.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Arch_ATPase PF01637.13 OAP61484.1 - 0.37 10.4 0.0 36 3.9 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase DUF3425 PF11905.3 OAP61486.1 - 1.5e-23 83.1 1.3 3.6e-23 81.9 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_6 PF12697.2 OAP61488.1 - 8.1e-15 55.3 0.1 1.3e-14 54.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP61488.1 - 5.7e-05 22.8 0.0 0.0001 22.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP61488.1 - 0.0022 17.6 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 OAP61488.1 - 0.035 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Acetate_kinase PF00871.12 OAP61489.1 - 1.1e-97 327.1 0.2 1.3e-97 326.8 0.1 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.5 OAP61490.1 - 2.4e-102 342.3 0.1 3e-102 342.0 0.1 1.0 1 0 0 1 1 1 1 XFP N-terminal domain TPP_enzyme_C PF02775.16 OAP61490.1 - 0.023 14.2 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP PF03894.10 OAP61491.1 - 1.5e-69 233.1 0.0 2.5e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 OAP61491.1 - 3.1e-69 232.4 0.0 4.4e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP_N PF09364.5 OAP61491.1 - 8e-45 153.0 0.0 1.1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain SH3_9 PF14604.1 OAP61491.1 - 0.018 14.6 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Transketolase_C PF02780.15 OAP61491.1 - 0.091 12.7 0.2 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Transketolase, C-terminal domain SH3_2 PF07653.12 OAP61491.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain MFS_1 PF07690.11 OAP61493.1 - 2.6e-33 115.2 37.6 9.3e-33 113.3 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP61493.1 - 5.1e-06 24.9 1.1 5.1e-06 24.9 0.8 2.4 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) CHCH PF06747.8 OAP61494.1 - 7.4e-11 41.6 6.4 1.9e-08 33.9 1.4 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 OAP61494.1 - 0.0091 15.7 8.8 0.42 10.4 1.7 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 OAP61494.1 - 0.38 10.8 7.0 0.58 10.2 0.7 2.7 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Elf1 PF05129.8 OAP61495.1 - 2.1 8.1 5.1 3.9 7.2 3.5 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like RHD3 PF05879.7 OAP61496.1 - 0 1038.2 0.0 0 1037.8 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 OAP61496.1 - 3e-07 29.7 0.2 5.1e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 OAP61496.1 - 9e-07 28.8 0.1 2.7e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 OAP61496.1 - 2.1e-05 24.4 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 OAP61496.1 - 0.00019 21.3 0.0 0.00059 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 OAP61496.1 - 0.0012 19.3 0.0 0.0026 18.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 OAP61496.1 - 0.0087 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Septin FtsK_SpoIIIE PF01580.13 OAP61496.1 - 0.053 12.9 0.4 6.4 6.1 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Peptidase_M18 PF02127.10 OAP61497.1 - 6.4e-133 443.4 0.0 7.3e-133 443.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) MFS_1 PF07690.11 OAP61499.1 - 3.7e-33 114.7 36.9 3.7e-33 114.7 25.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.8 OAP61500.1 - 3.1e-38 131.3 0.0 4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP61500.1 - 2.8e-09 37.2 0.0 3.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP61500.1 - 1e-05 24.3 0.0 1.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP61500.1 - 1.2e-05 24.9 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 OAP61500.1 - 0.0035 17.3 0.1 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 OAP61500.1 - 0.0054 16.4 0.1 0.0085 15.7 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 OAP61500.1 - 0.037 13.9 0.3 0.075 12.9 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase UQ_con PF00179.21 OAP61501.1 - 2.4e-51 172.8 0.0 2.6e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP61501.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B TP6A_N PF04406.9 OAP61502.1 - 2.9e-19 68.5 0.2 5.6e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Prenyltrans PF00432.16 OAP61503.1 - 1.5e-34 117.2 0.7 1.1e-12 47.2 0.0 5.1 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAP61503.1 - 6.9e-29 100.5 1.4 5.7e-15 55.6 0.1 4.5 3 1 1 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAP61503.1 - 3.3e-27 94.6 0.1 5.4e-17 61.7 0.1 5.3 5 1 1 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 OAP61503.1 - 0.0001 21.5 4.1 1.1 8.3 0.0 4.9 5 1 1 6 6 6 3 Pectic acid lyase A2M_comp PF07678.9 OAP61503.1 - 0.00034 19.9 0.1 0.32 10.2 0.0 3.7 3 1 1 4 4 4 2 A-macroglobulin complement component FAD_binding_3 PF01494.14 OAP61504.1 - 3.1e-06 26.4 3.4 0.00017 20.7 2.4 2.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP61504.1 - 0.0028 17.5 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP61504.1 - 0.0039 16.1 0.0 0.011 14.7 0.0 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 OAP61504.1 - 0.0046 15.4 1.7 0.0095 14.4 0.2 2.1 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 OAP61504.1 - 0.0049 16.8 0.4 0.0049 16.8 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP61504.1 - 0.0075 15.2 0.4 0.011 14.6 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP61504.1 - 0.01 15.6 0.4 0.24 11.1 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 OAP61504.1 - 0.021 14.3 0.1 0.043 13.3 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 OAP61504.1 - 0.037 14.4 0.3 0.095 13.1 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP61504.1 - 0.052 12.3 0.4 0.08 11.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 OAP61504.1 - 0.079 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 OAP61504.1 - 0.094 12.7 0.1 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP61504.1 - 0.26 9.8 1.1 0.84 8.1 0.3 2.0 1 1 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.11 OAP61505.1 - 6.1e-14 51.4 80.9 2.5e-11 42.9 33.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 OAP61506.1 - 2.6e-19 69.7 1.4 3.1e-19 69.5 0.2 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.3 OAP61507.1 - 1.7e-13 49.9 1.8 3.2e-13 49.0 0.2 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Ank_2 PF12796.2 OAP61509.1 - 4.4e-100 328.2 9.3 7.6e-18 64.6 0.1 10.0 6 3 4 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 OAP61509.1 - 2.7e-74 241.5 30.6 5.2e-07 29.1 0.0 20.6 21 0 0 21 21 21 16 Ankyrin repeat Ank_4 PF13637.1 OAP61509.1 - 1.3e-58 194.4 9.3 4.3e-09 36.6 0.0 15.3 11 5 5 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP61509.1 - 2.4e-57 185.1 11.1 3.3e-05 23.7 0.0 20.5 21 1 1 22 22 22 10 Ankyrin repeat Ank_5 PF13857.1 OAP61509.1 - 2.1e-42 142.2 13.9 3.2e-05 24.0 0.0 15.6 7 4 11 18 18 18 9 Ankyrin repeats (many copies) DUF3447 PF11929.3 OAP61509.1 - 5.3e-07 29.3 0.0 0.02 14.6 0.0 5.3 5 1 1 6 6 6 1 Domain of unknown function (DUF3447) Phage_T7_Capsid PF05396.6 OAP61509.1 - 0.00043 20.4 2.5 6.7 6.8 0.1 4.8 4 1 0 5 5 5 2 Phage T7 capsid assembly protein Shigella_OspC PF06128.6 OAP61509.1 - 0.0019 17.7 0.4 4.8 6.6 0.0 5.0 6 0 0 6 6 6 1 Shigella flexneri OspC protein gag-asp_proteas PF13975.1 OAP61509.1 - 0.086 12.6 2.4 0.71 9.7 0.0 3.6 5 0 0 5 5 5 0 gag-polyprotein putative aspartyl protease DUF4243 PF14027.1 OAP61511.1 - 7.8e-105 350.9 2.4 9.1e-105 350.7 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3632 PF12311.3 OAP61511.1 - 0.0091 15.8 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) adh_short PF00106.20 OAP61512.1 - 9.1e-22 77.7 0.0 1.4e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP61512.1 - 6.3e-20 71.9 0.0 8.6e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP61512.1 - 9.2e-07 28.6 0.0 4.4e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAP61512.1 - 0.00036 20.2 0.0 0.00086 19.0 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAP61512.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP61512.1 - 0.003 17.0 0.0 0.0036 16.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 OAP61512.1 - 0.0047 16.7 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 OAP61512.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 OAP61512.1 - 0.046 13.0 0.0 0.096 12.0 0.0 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 OAP61512.1 - 0.053 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_25 PF13649.1 OAP61512.1 - 0.07 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 OAP61512.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain TTKRSYEDQ PF10212.4 OAP61512.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Methyltransf_11 PF08241.7 OAP61512.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain APC8 PF04049.8 OAP61515.1 - 3.5e-49 166.2 0.7 1.1e-47 161.2 0.0 2.5 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 OAP61515.1 - 9.7e-21 72.4 3.7 0.00022 20.6 0.0 6.7 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAP61515.1 - 4.4e-18 64.6 16.2 5.1e-07 29.2 0.1 6.7 6 1 1 7 7 6 3 TPR repeat TPR_2 PF07719.12 OAP61515.1 - 7.9e-16 56.6 16.6 0.017 15.0 0.0 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAP61515.1 - 1.3e-15 56.4 17.6 0.0061 17.1 0.0 8.5 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 OAP61515.1 - 7.8e-13 48.7 27.2 2.8e-05 24.6 0.1 7.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAP61515.1 - 3.2e-12 45.2 9.2 0.00012 21.6 0.0 6.8 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAP61515.1 - 3.3e-09 36.2 4.1 3.1 8.2 0.0 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAP61515.1 - 6.1e-09 35.6 18.6 0.15 11.9 1.3 7.2 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAP61515.1 - 3.8e-07 30.1 17.6 5 7.8 0.0 9.2 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 OAP61515.1 - 3.9e-07 30.1 17.8 0.24 11.5 0.3 5.7 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 OAP61515.1 - 2.3e-06 27.8 18.0 0.008 16.4 0.2 6.7 8 1 0 8 8 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAP61515.1 - 3.6e-06 26.3 9.8 0.73 9.7 0.0 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAP61515.1 - 0.00025 20.8 11.3 0.0016 18.2 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAP61515.1 - 0.0031 17.3 5.9 6.4 6.8 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat ChAPs PF09295.5 OAP61515.1 - 0.012 14.3 0.1 14 4.3 0.0 3.2 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.15 OAP61515.1 - 1 9.4 4.5 30 4.8 0.1 3.8 4 0 0 4 4 4 0 PPR repeat Pro_racemase PF05544.6 OAP61516.1 - 2e-61 207.6 0.0 2.7e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Proline racemase SNARE PF05739.14 OAP61517.1 - 9.7e-08 31.5 0.7 9.7e-08 31.5 0.5 1.8 1 1 1 2 2 2 1 SNARE domain Apc15p PF05841.6 OAP61518.1 - 4.1e-11 43.6 1.3 9.8e-11 42.4 0.1 2.3 2 0 0 2 2 2 1 Apc15p protein Glu_synthase PF01645.12 OAP61519.1 - 1.5e-159 530.8 0.0 3e-159 529.8 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 OAP61519.1 - 1.2e-138 461.7 0.0 1.6e-138 461.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 OAP61519.1 - 2.4e-120 401.1 0.0 4.3e-120 400.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 OAP61519.1 - 1.5e-66 223.2 4.2 2.8e-66 222.3 2.9 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 OAP61519.1 - 3.7e-22 78.0 0.1 9.5e-22 76.7 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 OAP61519.1 - 1.7e-18 67.2 0.0 6.1e-18 65.4 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP61519.1 - 1.7e-09 38.0 0.4 0.00025 21.1 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP61519.1 - 3.4e-07 30.1 0.0 1.2e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAP61519.1 - 2.7e-05 24.4 0.0 0.014 15.8 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP61519.1 - 9.9e-05 21.5 0.1 0.00017 20.8 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 OAP61519.1 - 0.00025 19.6 0.2 0.00054 18.5 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 OAP61519.1 - 0.00066 18.6 0.0 0.003 16.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 OAP61519.1 - 0.0014 17.5 2.1 0.0017 17.3 0.2 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 OAP61519.1 - 0.0016 18.0 0.1 0.007 15.9 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 OAP61519.1 - 0.0016 17.5 0.5 0.014 14.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 OAP61519.1 - 0.0027 16.8 0.4 0.013 14.6 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 OAP61519.1 - 0.009 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAP61519.1 - 0.017 15.3 4.2 2.5 8.3 0.1 3.1 4 0 0 4 4 2 0 Putative NAD(P)-binding FMN_dh PF01070.13 OAP61519.1 - 0.03 13.1 2.0 0.14 10.9 0.9 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DJ-1_PfpI PF01965.19 OAP61519.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.8 1 1 1 2 2 2 0 DJ-1/PfpI family GIDA PF01134.17 OAP61519.1 - 0.13 11.0 1.1 0.32 9.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.14 OAP61519.1 - 0.27 9.4 0.1 2.3 6.3 0.0 2.3 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Nup54 PF13874.1 OAP61520.1 - 1.4e-33 115.4 6.0 1.4e-33 115.4 4.2 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 OAP61520.1 - 9.1e-13 48.4 77.5 4.7e-09 36.4 35.5 3.0 1 1 1 2 2 2 2 Nucleoporin FG repeat region Spc7 PF08317.6 OAP61520.1 - 0.00071 18.3 6.5 0.00071 18.3 4.5 1.8 1 1 1 2 2 2 1 Spc7 kinetochore protein Prominin PF05478.6 OAP61520.1 - 0.11 10.0 1.8 0.16 9.4 1.2 1.2 1 0 0 1 1 1 0 Prominin DUF342 PF03961.8 OAP61520.1 - 0.53 8.6 10.0 0.12 10.7 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Sporozoite_P67 PF05642.6 OAP61520.1 - 1.5 6.5 8.2 2.1 6.1 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tom5 PF10642.4 OAP61521.1 - 2.4e-10 39.8 0.0 3.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase MFS_1 PF07690.11 OAP61522.1 - 8.5e-29 100.3 32.2 1.3e-28 99.7 22.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TcpE PF12648.2 OAP61522.1 - 7.7 6.7 7.2 4 7.6 1.4 2.7 2 0 0 2 2 2 0 TcpE family Gly-zipper_OmpA PF13436.1 OAP61523.1 - 0.035 13.7 0.8 0.067 12.8 0.5 1.6 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PAN_4 PF14295.1 OAP61523.1 - 0.17 11.6 5.2 1.9 8.2 1.4 2.8 2 1 0 2 2 2 0 PAN domain Flp_Fap PF04964.9 OAP61523.1 - 0.22 11.1 1.6 0.42 10.2 1.1 1.4 1 0 0 1 1 1 0 Flp/Fap pilin component DUF822 PF05687.8 OAP61523.1 - 0.93 9.8 6.7 0.19 12.0 0.6 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) Med26 PF08711.6 OAP61524.1 - 1.7e-14 53.0 0.0 3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF2413 PF10310.4 OAP61524.1 - 3.4 6.3 11.2 5.9 5.5 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) HIG_1_N PF04588.8 OAP61525.1 - 6e-08 32.3 1.1 1.2e-07 31.3 0.8 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Romo1 PF10247.4 OAP61525.1 - 1.3 9.3 4.9 2.4 8.3 0.5 2.8 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 4HBT_2 PF13279.1 OAP61526.1 - 3.2e-10 40.5 0.0 6.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Chitin_bind_3 PF03067.10 OAP61527.1 - 0.0017 18.6 0.0 0.021 15.0 0.0 2.4 3 0 0 3 3 3 1 Chitin binding domain Glyco_hydro_61 PF03443.9 OAP61527.1 - 0.0029 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 His_Phos_2 PF00328.17 OAP61528.1 - 8.7e-33 114.0 0.0 1.2e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 OAP61528.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Ank_2 PF12796.2 OAP61529.1 - 2.9e-109 357.6 19.6 7.7e-19 67.8 0.0 10.5 2 2 8 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 OAP61529.1 - 3.7e-104 335.7 18.7 1.5e-08 34.0 0.0 17.7 19 0 0 19 19 19 15 Ankyrin repeat Ank_4 PF13637.1 OAP61529.1 - 2.2e-75 247.8 16.1 8.1e-10 38.9 0.0 13.8 8 4 6 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP61529.1 - 3.6e-75 240.3 9.6 1.2e-05 25.0 0.0 18.6 19 0 0 19 19 19 13 Ankyrin repeat Ank_5 PF13857.1 OAP61529.1 - 6.8e-73 239.0 19.5 9.5e-11 41.5 0.0 16.1 3 3 16 19 19 19 14 Ankyrin repeats (many copies) CorA PF01544.13 OAP61529.1 - 1.7e-09 37.1 0.9 3.7e-09 36.0 0.6 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Blt1 PF12754.2 OAP61530.1 - 5.9e-34 118.0 0.0 7.6e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Cell-cycle control medial ring component ubiquitin PF00240.18 OAP61530.1 - 0.033 13.5 0.4 0.067 12.5 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family Cadherin_C PF01049.12 OAP61531.1 - 0.26 11.3 2.0 0.42 10.6 0.1 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic region DUF2072 PF09845.4 OAP61531.1 - 7.8 6.4 9.7 0.046 13.6 0.6 1.8 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) ketoacyl-synt PF00109.21 OAP61532.1 - 5e-70 235.8 0.0 9.6e-70 234.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 OAP61532.1 - 1.1e-42 146.5 0.0 3.1e-42 145.0 0.0 1.8 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 OAP61532.1 - 1.7e-34 118.2 0.0 5.8e-34 116.4 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 OAP61532.1 - 2.9e-25 89.8 0.0 8.6e-25 88.3 0.0 1.9 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 OAP61532.1 - 9e-21 73.9 6.9 4.3e-11 42.9 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 OAP61532.1 - 6.2e-15 55.1 0.0 1.2e-13 50.8 0.0 2.4 2 0 0 2 2 2 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 OAP61532.1 - 2.2e-07 30.7 0.0 0.0085 15.8 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP61532.1 - 7.9e-07 29.1 0.4 0.00026 20.9 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 OAP61532.1 - 0.0061 15.5 0.0 0.015 14.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Fungal_trans_2 PF11951.3 OAP61533.1 - 5.4e-27 94.3 1.0 9.1e-26 90.3 0.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61533.1 - 0.00044 20.1 3.8 0.00077 19.3 2.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 OAP61534.1 - 3e-22 78.5 0.0 7.3e-22 77.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain MFS_1 PF07690.11 OAP61535.1 - 3.6e-07 29.2 37.1 4.3e-05 22.3 22.1 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 OAP61535.1 - 4.4e-06 26.2 7.2 4.4e-06 26.2 5.0 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2755 PF10954.3 OAP61535.1 - 0.017 14.7 0.3 1.9 8.2 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) LAB_N PF07578.6 OAP61535.1 - 0.48 10.3 8.2 0.28 11.1 2.2 3.1 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain Amidase PF01425.16 OAP61536.1 - 3.3e-94 316.2 0.0 3.8e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Amidase PhyH PF05721.8 OAP61537.1 - 1.1e-20 74.5 0.0 1.9e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-CHY PF05495.7 OAP61537.1 - 0.0055 16.8 2.4 0.01 15.9 1.7 1.4 1 0 0 1 1 1 1 CHY zinc finger HypA PF01155.14 OAP61537.1 - 0.016 14.8 0.2 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 OAP61537.1 - 0.03 14.3 3.0 0.06 13.3 2.1 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain DUF2197 PF09963.4 OAP61537.1 - 0.093 12.7 1.4 0.17 11.8 0.5 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-RING_3 PF14369.1 OAP61537.1 - 0.14 12.1 1.8 0.38 10.7 1.2 1.8 1 1 1 2 2 2 0 zinc-finger Evr1_Alr PF04777.8 OAP61537.1 - 0.23 11.3 2.0 0.84 9.5 1.3 1.9 1 1 0 1 1 1 0 Erv1 / Alr family Zn-ribbon_8 PF09723.5 OAP61537.1 - 0.29 11.1 3.4 0.5 10.3 2.4 1.4 1 0 0 1 1 1 0 Zinc ribbon domain TALPID3 PF15324.1 OAP61537.1 - 7.8 3.7 6.9 11 3.2 4.8 1.1 1 0 0 1 1 1 0 Hedgehog signalling target zf-H2C2_2 PF13465.1 OAP61537.1 - 8.2 6.9 7.0 4.7 7.6 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Proteasome PF00227.21 OAP61538.1 - 2.3e-54 183.5 0.1 3e-54 183.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAP61538.1 - 1.2e-13 50.1 0.1 2.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CHCC PF10276.4 OAP61539.1 - 6.6e-14 51.4 2.4 1e-13 50.8 1.7 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 OAP61539.1 - 0.17 11.5 1.1 7.2 6.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb MFS_1 PF07690.11 OAP61540.1 - 7.4e-42 143.3 49.4 1.5e-41 142.3 34.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP61540.1 - 3.3e-11 42.0 16.6 4.5e-11 41.6 11.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cu-oxidase_2 PF07731.9 OAP61541.1 - 3.3e-41 140.0 1.9 8.4e-36 122.5 0.0 3.5 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 OAP61541.1 - 6.3e-38 129.1 16.4 7.3e-37 125.6 1.4 5.0 4 1 1 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.17 OAP61541.1 - 8.9e-26 90.6 1.5 4.7e-25 88.3 0.3 2.5 2 0 0 2 2 2 1 Multicopper oxidase DUF4267 PF14087.1 OAP61542.1 - 1.2e-20 73.2 2.6 1.5e-20 72.9 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Fungal_trans PF04082.13 OAP61543.1 - 5.3e-18 64.8 0.0 8.9e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61543.1 - 1.5e-08 34.3 12.1 2.6e-08 33.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NuA4 PF09340.5 OAP61543.1 - 0.23 11.1 0.2 0.49 10.0 0.2 1.5 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DLH PF01738.13 OAP61544.1 - 4.1e-19 68.7 0.0 1e-18 67.4 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP61544.1 - 2.2e-06 27.4 0.0 3.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family 2H-phosphodiest PF08975.5 OAP61545.1 - 1.5e-35 121.4 0.0 2.3e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) 2_5_RNA_ligase2 PF13563.1 OAP61545.1 - 0.00026 20.7 0.8 0.00077 19.2 0.5 1.7 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily HVSL PF09749.4 OAP61545.1 - 0.018 14.0 0.1 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein CutC PF03932.9 OAP61546.1 - 8e-64 214.6 0.0 9.6e-64 214.3 0.0 1.0 1 0 0 1 1 1 1 CutC family Aldolase PF01081.14 OAP61546.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase DHquinase_I PF01487.10 OAP61546.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Type I 3-dehydroquinase UPF0047 PF01894.12 OAP61547.1 - 4.3e-41 139.4 0.0 5e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 FoP_duplication PF13865.1 OAP61549.1 - 1.6 9.2 7.2 3.2 8.2 5.0 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Histone PF00125.19 OAP61550.1 - 4.1e-22 78.0 0.0 5.6e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAP61550.1 - 4.8e-05 23.3 0.0 7.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 OAP61551.1 - 1.1e-12 47.4 0.3 2.1e-12 46.5 0.2 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 OAP61551.1 - 1.8e-07 31.0 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP61551.1 - 2.1e-06 27.2 0.0 4.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP61551.1 - 0.00047 19.9 0.0 0.00099 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 OAP61551.1 - 0.038 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Aldo_ket_red PF00248.16 OAP61552.1 - 8.2e-18 64.2 0.1 4e-17 61.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family CO_deh_flav_C PF03450.12 OAP61552.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain HSF_DNA-bind PF00447.12 OAP61553.1 - 7.5e-29 99.9 0.1 1.9e-28 98.6 0.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Tmemb_cc2 PF10267.4 OAP61553.1 - 0.0077 14.8 0.7 0.014 13.9 0.5 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein CCDC-167 PF15188.1 OAP61553.1 - 0.061 13.2 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Occludin_ELL PF07303.8 OAP61553.1 - 0.56 10.9 3.3 0.52 11.0 0.7 2.0 2 0 0 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.7 OAP61553.1 - 3.3 7.5 7.0 4.2 7.1 2.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.11 OAP61554.1 - 3.7e-15 55.4 50.6 5e-08 32.0 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EmrE PF13536.1 OAP61555.1 - 0.11 12.7 9.2 1.5 9.0 0.6 2.2 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DUF1011 PF06237.7 OAP61555.1 - 0.32 10.9 2.5 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) HET PF06985.6 OAP61556.1 - 2.1e-19 70.0 0.7 1e-12 48.3 0.1 2.9 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_jaz PF12171.3 OAP61557.1 - 0.024 14.7 1.5 0.21 11.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAP61557.1 - 0.097 12.6 0.6 5.8 6.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 OAP61557.1 - 2.9 8.4 6.3 6 7.4 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Pyr_redox_3 PF13738.1 OAP61558.1 - 8.9e-22 78.1 0.1 3.8e-21 76.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP61558.1 - 3.5e-11 43.3 0.0 4.5e-06 26.6 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP61558.1 - 3.5e-10 38.7 0.0 6.4e-10 37.8 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP61558.1 - 1.2e-08 34.2 0.0 3.2e-06 26.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 OAP61558.1 - 0.00011 22.5 0.5 3.6 8.0 0.0 4.0 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP61558.1 - 0.00081 18.5 0.1 0.01 14.9 0.0 2.7 4 0 0 4 4 4 1 Thi4 family Lycopene_cycl PF05834.7 OAP61558.1 - 0.0018 17.2 0.1 0.038 12.9 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.15 OAP61558.1 - 0.002 18.2 0.2 0.066 13.3 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 OAP61558.1 - 0.0041 16.7 0.1 0.8 9.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 OAP61558.1 - 0.0054 16.7 0.0 0.028 14.4 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAP61558.1 - 0.0064 15.5 0.0 0.017 14.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 OAP61558.1 - 0.023 13.2 0.5 0.44 8.9 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 OAP61558.1 - 0.033 13.0 1.5 0.11 11.3 0.3 2.3 2 1 0 2 2 2 0 FAD binding domain F420_oxidored PF03807.12 OAP61558.1 - 0.047 14.1 0.1 15 6.0 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 OAP61558.1 - 0.063 12.7 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 OAP61558.1 - 0.086 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 OAP61558.1 - 0.3 11.1 2.3 15 5.5 0.0 2.9 4 0 0 4 4 4 0 TrkA-N domain DAO PF01266.19 OAP61558.1 - 1.8 7.3 8.1 0.25 10.2 0.1 3.3 5 0 0 5 5 5 0 FAD dependent oxidoreductase Phosphoprotein PF00922.12 OAP61560.1 - 3 6.9 10.7 0.14 11.3 0.7 2.1 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein Glug PF07581.7 OAP61561.1 - 7.8 6.9 10.6 1.7 8.9 2.7 3.3 3 0 0 3 3 3 0 The GLUG motif FMN_dh PF01070.13 OAP61562.1 - 4.9e-108 361.1 0.0 7.9e-108 360.4 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAP61562.1 - 2.5e-18 65.6 0.0 4.6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAP61562.1 - 4.3e-05 22.5 0.0 6.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAP61562.1 - 0.00022 20.2 0.8 0.00072 18.5 0.1 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 OAP61562.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 OAP61562.1 - 0.014 14.4 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Shisa PF13908.1 OAP61563.1 - 0.47 10.6 4.2 0.16 12.1 0.2 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF3218 PF11508.3 OAP61567.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) Fibrinogen_aC PF12160.3 OAP61567.1 - 0.3 10.5 1.5 0.43 10.0 1.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha C domain Pro_isomerase PF00160.16 OAP61568.1 - 1.2e-35 122.9 0.0 2.1e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pyr_redox_3 PF13738.1 OAP61569.1 - 1.2e-24 87.5 0.0 5.9e-24 85.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP61569.1 - 5e-24 84.4 0.0 4.2e-22 78.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP61569.1 - 5.4e-10 39.1 0.0 1.4e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP61569.1 - 7.1e-08 31.7 0.0 2.3e-05 23.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP61569.1 - 0.0056 16.4 0.4 0.17 11.6 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD-oxidase_C PF02913.14 OAP61570.1 - 1.1e-58 198.4 0.0 1.5e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAP61570.1 - 3.5e-38 130.2 0.2 1e-37 128.6 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain PBP_like_2 PF12849.2 OAP61570.1 - 0.029 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain Aldolase_II PF00596.16 OAP61572.1 - 2.1e-28 99.1 0.8 2.7e-28 98.8 0.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GatB_N PF02934.10 OAP61572.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 GatB/GatE catalytic domain ABM PF03992.11 OAP61573.1 - 0.068 13.2 0.2 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase FAD_binding_3 PF01494.14 OAP61574.1 - 1e-17 64.2 5.4 9.1e-10 38.1 1.6 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP61574.1 - 2.9e-07 29.7 0.0 1.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP61574.1 - 1.1e-05 25.3 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP61574.1 - 9.6e-05 21.3 0.0 0.00018 20.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 OAP61574.1 - 0.00015 22.1 0.9 0.016 15.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP61574.1 - 0.00035 20.6 0.1 0.00056 20.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP61574.1 - 0.0045 15.9 0.1 0.0064 15.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAP61574.1 - 0.0068 16.3 0.1 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAP61574.1 - 0.0085 16.0 0.2 0.021 14.8 0.1 1.7 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.12 OAP61574.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 OAP61574.1 - 0.02 13.3 0.2 0.28 9.5 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 OAP61574.1 - 0.043 13.3 0.3 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 OAP61574.1 - 0.049 13.2 0.1 0.095 12.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Beta_helix PF13229.1 OAP61575.1 - 9.1e-09 35.2 15.3 1.9e-06 27.7 6.9 2.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 OAP61575.1 - 0.00011 21.4 6.3 0.018 14.1 4.4 2.2 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Methyltransf_23 PF13489.1 OAP61576.1 - 1.6e-19 70.1 0.0 2.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61576.1 - 1.7e-10 41.4 0.0 5.8e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP61576.1 - 4.9e-08 32.7 0.0 0.002 17.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 OAP61576.1 - 1.6e-07 31.6 0.0 3.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP61576.1 - 2e-05 25.0 0.0 5.2e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP61576.1 - 0.00024 21.1 0.0 0.003 17.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAP61576.1 - 0.0015 17.6 0.0 0.0034 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 OAP61576.1 - 0.0035 16.4 0.0 0.0086 15.1 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 OAP61576.1 - 0.006 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 OAP61576.1 - 0.0099 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 OAP61576.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 OAP61576.1 - 0.037 13.4 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 OAP61576.1 - 0.039 14.2 0.0 0.22 11.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 OAP61576.1 - 0.062 12.8 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Glyco_transf_4 PF13439.1 OAP61576.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 p450 PF00067.17 OAP61577.1 - 8.3e-56 189.4 0.0 9.8e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C1 PF00112.18 OAP61580.1 - 7.5e-05 22.7 0.0 0.0053 16.6 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Abhydrolase_6 PF12697.2 OAP61581.1 - 9.5e-22 77.9 3.2 1.5e-21 77.3 2.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP61581.1 - 7.5e-10 38.7 0.0 1.2e-09 38.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hexokinase_2 PF03727.11 OAP61582.1 - 7.7e-72 241.4 0.0 1.4e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 OAP61582.1 - 1.5e-68 230.2 0.0 2e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Isochorismatase PF00857.15 OAP61582.1 - 0.057 13.3 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Isochorismatase family TAFII28 PF04719.9 OAP61583.1 - 2.7e-14 52.7 0.2 9.6e-14 50.9 0.1 1.9 2 0 0 2 2 2 1 hTAFII28-like protein conserved region AT_hook PF02178.14 OAP61583.1 - 0.0032 16.9 1.9 0.014 14.9 1.3 2.2 1 0 0 1 1 1 1 AT hook motif Tannase PF07519.6 OAP61584.1 - 4.3e-81 273.0 0.3 5.8e-81 272.5 0.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 OAP61584.1 - 0.0023 17.8 0.0 0.009 15.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP61584.1 - 0.004 16.7 0.0 0.0086 15.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ank_2 PF12796.2 OAP61585.1 - 1.6e-21 76.4 0.2 3e-14 53.1 0.0 3.5 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAP61585.1 - 1.4e-13 49.9 3.7 0.00051 19.7 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 OAP61585.1 - 4.6e-11 41.8 0.8 0.016 15.4 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 OAP61585.1 - 2.5e-10 40.5 0.9 4.5e-07 30.2 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP61585.1 - 9.9e-07 28.8 0.9 0.00048 20.2 0.0 4.2 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Pyr_redox_3 PF13738.1 OAP61586.1 - 4.5e-20 72.5 0.0 6.3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP61586.1 - 4.1e-14 51.6 0.5 3.2e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP61586.1 - 8.3e-10 38.8 0.0 1.4e-08 34.9 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP61586.1 - 2.1e-09 37.2 0.0 3.3e-07 30.2 0.0 3.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP61586.1 - 3.9e-09 35.8 0.0 1.7e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAP61586.1 - 4.9e-09 35.5 0.0 0.00013 20.9 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP61586.1 - 0.00053 19.0 0.1 0.0025 16.8 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP61586.1 - 0.0018 17.2 0.0 0.0033 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAP61586.1 - 0.0026 16.8 0.3 0.0062 15.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 OAP61586.1 - 0.014 15.2 6.0 2.1 8.0 0.9 4.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 OAP61586.1 - 0.016 14.3 0.1 0.031 13.3 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 OAP61586.1 - 0.019 13.8 1.0 0.51 9.1 0.1 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.9 OAP61586.1 - 0.022 13.2 1.2 0.26 9.6 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.22 OAP61586.1 - 0.06 13.7 0.9 12 6.4 0.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Beta-lactamase PF00144.19 OAP61587.1 - 3e-44 151.4 0.0 6e-44 150.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 OAP61587.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Zn_clus PF00172.13 OAP61588.1 - 4.5e-06 26.4 12.4 2.4e-05 24.1 8.6 2.1 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 OAP61588.1 - 1.8 8.7 7.6 13 6.0 2.0 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region HET PF06985.6 OAP61589.1 - 8.3e-22 77.8 9.6 6.2e-19 68.5 2.2 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SAM_decarbox PF01536.11 OAP61590.1 - 2.3e-86 289.4 0.0 9.3e-85 284.2 0.0 2.4 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.4 OAP61591.1 - 1.7e-33 114.3 0.7 7.1e-33 112.3 0.5 2.1 1 1 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAP61591.1 - 3.7e-13 49.3 0.0 1.8e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 OAP61591.1 - 1.2e-08 34.3 0.0 3e-07 29.7 0.0 2.1 1 1 1 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 OAP61591.1 - 6.9e-08 32.5 0.0 2.4e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 OAP61591.1 - 1.6e-05 24.0 0.1 3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 OAP61591.1 - 0.00031 20.2 0.0 0.00058 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 OAP61591.1 - 0.00052 19.4 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 YhjQ protein ArgK PF03308.11 OAP61591.1 - 0.00097 17.9 0.2 0.0015 17.3 0.1 1.2 1 0 0 1 1 1 1 ArgK protein AAA_26 PF13500.1 OAP61591.1 - 0.016 14.8 0.8 0.41 10.2 0.2 2.4 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.15 OAP61591.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.17 OAP61591.1 - 0.024 14.0 0.0 0.82 9.0 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Desulfoferrod_N PF06397.7 OAP61591.1 - 0.028 13.7 1.0 0.06 12.7 0.7 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain DUF258 PF03193.11 OAP61591.1 - 0.082 12.0 1.4 0.14 11.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 OAP61591.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Amidohydro_1 PF01979.15 OAP61593.1 - 9.1e-33 114.2 0.1 1.2e-32 113.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAP61593.1 - 6.2e-08 32.9 1.4 0.00011 22.2 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 OAP61593.1 - 1.2e-06 28.0 0.3 1.6e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 OAP61593.1 - 8.8e-05 22.2 0.0 0.00029 20.5 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 OAP61593.1 - 0.084 11.7 0.0 0.22 10.4 0.0 1.6 2 0 0 2 2 2 0 Adenosine/AMP deaminase SnoaL_4 PF13577.1 OAP61594.1 - 1.9e-24 85.9 0.6 2.7e-24 85.4 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain RPE65 PF03055.10 OAP61595.1 - 1e-123 413.4 0.0 1.2e-123 413.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Aldedh PF00171.17 OAP61596.1 - 8.2e-159 528.8 1.1 9.2e-159 528.6 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 OAP61596.1 - 8.1e-05 21.9 0.1 0.23 10.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 OAP61596.1 - 0.0024 16.6 0.8 0.0046 15.7 0.6 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) His_Phos_2 PF00328.17 OAP61598.1 - 3.9e-28 98.7 0.0 1.1e-27 97.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) 2-Hacid_dh_C PF02826.14 OAP61599.1 - 3.3e-38 130.5 0.0 4.4e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP61599.1 - 7.7e-19 67.4 0.0 9.2e-19 67.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP61599.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase H_lectin PF09458.5 OAP61600.1 - 3.7e-35 119.4 0.0 6.2e-14 51.4 0.0 3.2 3 0 0 3 3 3 3 H-type lectin domain Peptidase_M10 PF00413.19 OAP61601.1 - 4.9e-06 26.3 1.1 0.00047 19.8 0.8 2.2 1 1 0 1 1 1 1 Matrixin Astacin PF01400.19 OAP61601.1 - 5.6e-06 25.8 0.2 1.5e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M43 PF05572.8 OAP61601.1 - 0.00058 19.5 0.0 0.00087 18.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 OAP61601.1 - 0.0017 18.4 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAP61601.1 - 0.0022 18.4 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAP61601.1 - 0.0077 16.1 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 OAP61601.1 - 0.027 13.8 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 OAP61601.1 - 0.027 13.9 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF1025 PF06262.6 OAP61601.1 - 0.073 12.8 0.1 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Metallopep PF12044.3 OAP61601.1 - 0.2 10.0 0.8 0.41 9.0 0.6 1.4 2 0 0 2 2 2 0 Putative peptidase family FAD_binding_3 PF01494.14 OAP61604.1 - 3.4e-86 289.5 0.0 6.2e-86 288.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 OAP61604.1 - 2e-57 193.4 0.0 3.3e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 OAP61604.1 - 0.0006 18.3 0.0 0.0012 17.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 OAP61604.1 - 0.0007 18.7 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 OAP61604.1 - 0.0021 17.9 0.1 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP61604.1 - 0.014 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 OAP61604.1 - 0.017 15.4 0.0 0.048 14.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP61604.1 - 0.021 14.8 0.0 0.084 12.9 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP61604.1 - 0.024 13.5 0.0 0.059 12.2 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 OAP61604.1 - 0.082 11.7 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3425 PF11905.3 OAP61605.1 - 3.8e-18 65.6 0.5 7.9e-18 64.6 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Ribonuc_L-PSP PF01042.16 OAP61606.1 - 4.8e-19 68.2 0.0 5.4e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Flavin_Reduct PF01613.13 OAP61607.1 - 6.7e-19 68.2 0.0 9.7e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Dabb PF07876.7 OAP61608.1 - 1.4e-09 38.2 0.0 1.7e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain p450 PF00067.17 OAP61609.1 - 1.4e-67 228.2 0.0 1.8e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 OAP61610.1 - 6.6e-23 81.3 0.3 5.5e-21 75.1 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP61610.1 - 8.5e-13 48.0 0.3 5.5e-05 22.4 0.1 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP61610.1 - 8.4e-12 45.0 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAP61610.1 - 4.6e-09 35.5 0.0 6.4e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.15 OAP61610.1 - 6.6e-07 29.0 0.0 1.2e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 OAP61610.1 - 8.7e-07 27.7 0.2 0.0019 16.7 0.0 2.2 1 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 OAP61610.1 - 3.5e-06 26.0 0.0 4.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.23 OAP61610.1 - 4.2e-06 25.7 0.2 3.2e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 OAP61610.1 - 5.2e-06 26.5 0.2 6.8e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 OAP61610.1 - 5.1e-05 22.6 0.2 0.22 10.7 0.0 2.3 2 1 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S15 PF02129.13 OAP61610.1 - 5.6e-05 22.7 0.0 0.00022 20.7 0.0 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 OAP61610.1 - 0.0002 20.8 0.6 0.063 12.7 0.0 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 OAP61610.1 - 0.0011 18.2 0.1 0.031 13.5 0.1 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2424 PF10340.4 OAP61610.1 - 0.016 13.9 0.1 2.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) DUF2920 PF11144.3 OAP61610.1 - 0.081 11.9 0.0 0.39 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) BAAT_C PF08840.6 OAP61610.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 OAP61610.1 - 0.11 11.6 0.1 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase MFS_1 PF07690.11 OAP61611.1 - 3.3e-28 98.4 24.6 3.3e-28 98.4 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3938 PF13074.1 OAP61611.1 - 0.04 13.7 2.3 4.4 7.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) Dioxygenase_C PF00775.16 OAP61612.1 - 2.3e-49 167.1 0.0 3.1e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 OAP61612.1 - 2.8e-18 65.6 0.0 6.7e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus ADH_zinc_N PF00107.21 OAP61613.1 - 6.6e-22 77.4 0.0 1.1e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP61613.1 - 1.8e-10 41.7 0.0 3.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_43 PF04616.9 OAP61614.1 - 7e-36 123.7 4.5 9.3e-36 123.3 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fe-ADH PF00465.14 OAP61615.1 - 3.2e-63 213.5 0.0 3.7e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAP61615.1 - 1.4e-11 44.2 0.0 1.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldo_ket_red PF00248.16 OAP61617.1 - 6.7e-46 156.3 0.0 8.5e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.17 OAP61618.1 - 1e-38 132.2 0.1 1.3e-38 131.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP61618.1 - 6.9e-12 45.9 0.0 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP61618.1 - 5.4e-10 38.7 0.1 6.9e-10 38.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAP61618.1 - 1.8e-07 30.7 0.0 2.4e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAP61618.1 - 5.9e-05 22.3 0.0 7e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Choline_transpo PF04515.7 OAP61619.1 - 1.4e-08 33.9 17.5 1.4e-08 33.9 12.1 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter PMT PF02366.13 OAP61620.1 - 1.1e-84 283.6 19.3 1.1e-84 283.6 13.4 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAP61620.1 - 6.7e-38 130.1 0.2 9.4e-38 129.6 0.2 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 OAP61620.1 - 6.9 6.2 7.4 0.84 9.1 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Fungal_trans PF04082.13 OAP61621.1 - 1.3e-13 50.4 0.7 2.7e-13 49.3 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61621.1 - 6.1e-06 26.0 13.7 1.1e-05 25.2 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 OAP61622.1 - 1.4e-33 116.3 0.2 1e-32 113.4 0.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP61622.1 - 0.0075 16.3 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase CAF1A PF12253.3 OAP61623.1 - 6.2e-18 64.6 7.0 6.2e-18 64.6 4.8 3.3 3 1 0 3 3 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 OAP61623.1 - 3.3e-06 26.6 46.7 2.1e-05 24.0 32.4 2.3 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spore_coat_CotO PF14153.1 OAP61623.1 - 0.0049 16.3 12.8 0.0049 16.3 8.9 1.6 2 0 0 2 2 2 1 Spore coat protein CotO MIP-T3 PF10243.4 OAP61623.1 - 0.36 9.2 33.0 0.17 10.3 20.4 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 OAP61623.1 - 0.96 7.8 22.7 0.38 9.1 8.8 2.2 2 0 0 2 2 2 0 Daxx Family CDC27 PF09507.5 OAP61623.1 - 1 8.4 30.2 0.011 15.0 14.5 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Ycf1 PF05758.7 OAP61623.1 - 1.2 6.7 16.6 1.8 6.1 11.5 1.1 1 0 0 1 1 1 0 Ycf1 Hex_IIIa PF02455.11 OAP61623.1 - 3.5 6.2 7.4 5.4 5.5 5.1 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) V_ATPase_I PF01496.14 OAP61623.1 - 3.5 5.3 8.5 5.3 4.7 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.7 OAP61623.1 - 7.3 6.3 27.2 0.02 14.8 11.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 OAP61623.1 - 7.8 6.2 13.1 17 5.1 9.0 1.5 1 0 0 1 1 1 0 DDHD domain Pmp3 PF01679.12 OAP61625.1 - 1.5e-20 72.6 9.8 1.9e-20 72.2 6.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ank PF00023.25 OAP61626.1 - 1.6e-22 78.1 0.0 2e-06 27.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 OAP61626.1 - 2.1e-21 76.0 0.0 1.5e-10 41.3 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 OAP61626.1 - 2.2e-16 58.3 0.6 5.5e-05 23.0 0.0 4.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 OAP61626.1 - 1.3e-14 53.8 0.2 0.00045 20.3 0.0 5.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP61626.1 - 7.8e-13 48.5 0.0 0.0058 17.1 0.0 4.7 4 1 0 4 4 4 3 Ankyrin repeats (many copies) TPR_12 PF13424.1 OAP61626.1 - 1.4e-09 37.7 5.8 4.1e-07 29.8 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP61626.1 - 1.3e-08 34.1 4.4 0.00014 21.4 0.6 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAP61626.1 - 6.6e-08 32.0 1.3 4e-06 26.3 0.3 3.3 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 OAP61626.1 - 9.4e-07 28.1 1.1 0.0031 17.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP61626.1 - 2.6e-06 27.6 1.2 4.8e-05 23.6 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP61626.1 - 5.6e-06 25.7 0.2 0.52 10.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP61626.1 - 7.4e-05 23.0 6.7 1.3 9.8 0.2 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAP61626.1 - 7.6e-05 22.2 0.2 0.35 10.7 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP61626.1 - 8e-05 23.2 0.1 8e-05 23.2 0.1 3.5 5 0 0 5 5 2 1 Tetratricopeptide repeat Apc3 PF12895.2 OAP61626.1 - 0.00075 19.5 0.1 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 OAP61626.1 - 0.00097 19.1 1.8 0.0028 17.6 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4398) TPR_10 PF13374.1 OAP61626.1 - 0.0028 17.5 4.8 3 7.9 0.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat HemY_N PF07219.8 OAP61626.1 - 0.01 15.3 0.8 0.029 13.9 0.1 2.0 2 0 0 2 2 2 0 HemY protein N-terminus TPR_6 PF13174.1 OAP61626.1 - 0.24 11.9 3.9 15 6.3 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 OAP61627.1 - 2.8e-20 72.2 0.0 4.4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HRDC PF00570.18 OAP61627.1 - 0.12 12.0 0.0 0.38 10.5 0.0 1.9 1 0 0 1 1 1 0 HRDC domain Ribosomal_L27 PF01016.14 OAP61629.1 - 1.3e-26 92.1 0.1 1.3e-26 92.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L27 protein TPR_11 PF13414.1 OAP61630.1 - 6.4e-11 41.7 0.1 1e-09 37.8 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 OAP61630.1 - 1.2e-07 31.0 0.0 0.11 12.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAP61630.1 - 3.2e-07 29.7 0.0 0.059 13.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.26 OAP61630.1 - 5.4e-06 26.0 0.0 1.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_12 PF13424.1 OAP61630.1 - 1.4e-05 24.8 0.4 0.00018 21.3 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.26 OAP61630.1 - 0.059 13.1 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain DUF1688 PF07958.6 OAP61631.1 - 4.3e-183 608.6 0.0 4.9e-183 608.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.7 OAP61632.1 - 1.8e-92 308.6 0.4 2.2e-92 308.3 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 OAP61632.1 - 4.4e-10 39.1 0.0 8.2e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.16 OAP61632.1 - 1.1e-07 31.3 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAP61632.1 - 3.4e-07 30.2 0.0 6.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAP61632.1 - 3.6e-06 27.4 0.2 8.3e-06 26.2 0.0 1.7 2 0 0 2 2 1 1 Miro-like protein GTP_EFTU PF00009.22 OAP61632.1 - 0.00011 21.7 0.1 0.0003 20.2 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 OAP61632.1 - 0.0019 17.6 0.5 0.0061 16.0 0.2 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 OAP61632.1 - 0.0068 16.7 0.6 0.015 15.5 0.1 1.9 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.11 OAP61632.1 - 0.014 14.4 1.2 0.05 12.7 0.2 2.3 2 1 0 2 2 2 0 AIG1 family SRPRB PF09439.5 OAP61632.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.8 OAP61632.1 - 0.017 14.0 0.1 0.039 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 OAP61632.1 - 0.041 13.0 0.1 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 OAP61632.1 - 0.072 12.1 0.2 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 OAP61632.1 - 0.11 11.9 0.2 0.24 10.7 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 OAP61632.1 - 0.15 11.5 0.2 0.83 9.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 OAP61632.1 - 0.82 8.2 3.6 2.3 6.8 0.7 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Zn_clus PF00172.13 OAP61633.1 - 1.3e-05 24.9 10.5 2.2e-05 24.2 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 OAP61634.1 - 5.2e-20 72.1 0.0 1.2e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP61634.1 - 4.5e-16 58.9 0.0 7.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.6 OAP61635.1 - 1.1e-09 37.6 0.0 1.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain CoA_transf_3 PF02515.12 OAP61638.1 - 2.2e-51 173.8 0.0 2.8e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Rhabdo_matrix PF03397.9 OAP61640.1 - 0.045 13.0 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus matrix protein Glyco_hydro_16 PF00722.16 OAP61641.1 - 0.00053 19.3 0.2 0.0007 18.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Amidase02_C PF12123.3 OAP61643.1 - 0.46 10.1 1.1 16 5.2 0.0 2.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase IPP-2 PF04979.9 OAP61644.1 - 7.4e-12 45.6 15.1 1.3e-06 28.7 0.8 2.4 1 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Pinin_SDK_memA PF04696.8 OAP61644.1 - 0.098 12.2 4.8 0.7 9.5 0.7 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Rad9_Rad53_bind PF08605.5 OAP61645.1 - 5.1e-17 61.8 0.0 7.9e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 OAP61645.1 - 0.0015 18.6 0.0 0.0039 17.3 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Presenilin PF01080.12 OAP61645.1 - 9.3 4.9 4.0 20 3.8 2.8 1.6 1 0 0 1 1 1 0 Presenilin Syndecan PF01034.15 OAP61646.1 - 0.00016 21.2 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.6 OAP61646.1 - 0.0013 18.3 0.2 0.029 14.0 0.0 2.2 2 0 0 2 2 2 1 Protocadherin Adeno_E3_CR2 PF02439.10 OAP61646.1 - 0.002 17.6 0.4 0.0039 16.7 0.3 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.13 OAP61646.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.1 OAP61646.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Fungal_trans PF04082.13 OAP61648.1 - 6.5e-10 38.3 1.2 1.1e-09 37.5 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61648.1 - 1e-09 38.1 13.0 2.1e-09 37.1 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_int_endo PF01974.12 OAP61649.1 - 3.3e-20 71.6 0.0 6.6e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 OAP61649.1 - 7.8e-08 31.7 0.0 3.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Ribosomal_L6e PF01159.14 OAP61649.1 - 0.15 12.2 0.8 0.32 11.2 0.5 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e Nop10p PF04135.7 OAP61650.1 - 2.2e-19 68.9 0.3 3.3e-19 68.3 0.2 1.3 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 OAP61651.1 - 1.7e-31 107.8 4.1 2.9e-31 107.1 2.8 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 OAP61651.1 - 0.0044 16.8 3.1 0.016 15.1 2.2 2.0 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator HypA PF01155.14 OAP61651.1 - 0.028 14.0 0.9 0.62 9.7 0.9 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-NADH-PPase PF09297.6 OAP61651.1 - 0.031 13.7 0.9 0.031 13.7 0.6 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF2890 PF11081.3 OAP61651.1 - 0.23 11.5 4.9 0.46 10.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DZR PF12773.2 OAP61651.1 - 1.1 9.1 5.1 2.1 8.2 3.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon MFS_1 PF07690.11 OAP61652.1 - 8.7e-22 77.3 36.2 1.2e-21 76.8 21.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily m04gp34like PF12216.3 OAP61652.1 - 0.11 11.8 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Immune evasion protein Glyco_hydro_16 PF00722.16 OAP61653.1 - 2.6e-08 33.3 0.0 6.5e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3103 PF11301.3 OAP61653.1 - 0.19 10.4 0.1 0.27 9.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) POT1 PF02765.12 OAP61654.1 - 2.1e-10 40.6 0.0 4.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Sdh_cyt PF01127.17 OAP61655.1 - 4.1e-22 78.2 6.9 5.6e-22 77.8 4.8 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Longin PF13774.1 OAP61656.1 - 0.038 13.5 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Regulated-SNARE-like domain Phosphoesterase PF04185.9 OAP61658.1 - 1.7e-55 188.7 4.0 1.2e-54 185.9 2.7 1.9 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.14 OAP61659.1 - 5e-60 202.6 1.8 5.9e-60 202.3 1.2 1.0 1 0 0 1 1 1 1 VIT family MFS_1 PF07690.11 OAP61660.1 - 2.2e-29 102.3 34.5 2.2e-29 102.3 23.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 OAP61660.1 - 0.041 11.9 4.8 0.083 10.9 0.3 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.23 OAP61661.1 - 7.4e-59 199.1 0.0 9.5e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP61661.1 - 4e-11 43.6 0.0 2.5e-10 41.1 0.0 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 OAP61662.1 - 1.8e-92 310.3 20.4 2.2e-92 310.0 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61662.1 - 2.6e-18 65.8 36.5 8e-14 51.1 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP61663.1 - 3.8e-18 65.2 0.0 6.9e-18 64.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Gpi1 PF05024.10 OAP61663.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) Acetyltransf_1 PF00583.19 OAP61664.1 - 4.1e-15 55.5 0.0 6.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP61664.1 - 1.5e-08 34.7 0.0 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAP61664.1 - 1.9e-06 28.0 0.0 2.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP61664.1 - 2.2e-06 27.3 0.0 5.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAP61664.1 - 4.1e-06 26.8 0.0 6.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP61664.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP61664.1 - 0.014 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 OAP61664.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4436 PF14494.1 OAP61665.1 - 0.00092 18.5 2.8 0.0014 18.0 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) SpoIIIAH PF12685.2 OAP61665.1 - 0.083 12.3 0.3 0.083 12.3 0.2 1.8 2 0 0 2 2 2 0 SpoIIIAH-like protein SPC22 PF04573.7 OAP61666.1 - 4e-34 117.3 0.0 2.6e-24 85.4 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit adh_short_C2 PF13561.1 OAP61667.1 - 5.9e-22 78.6 0.0 6.7e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP61667.1 - 1.4e-14 54.3 2.4 2.7e-14 53.4 1.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61667.1 - 4.1e-08 33.1 0.6 1.5e-07 31.2 0.5 1.7 2 0 0 2 2 2 1 KR domain Oxidored_nitro PF00148.14 OAP61667.1 - 0.00014 20.5 0.1 0.00019 20.2 0.1 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Eno-Rase_NADH_b PF12242.3 OAP61667.1 - 0.0023 17.6 0.7 0.0053 16.5 0.5 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 OAP61667.1 - 0.027 14.7 0.1 0.052 13.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding HHH_5 PF14520.1 OAP61667.1 - 0.061 13.5 0.0 10 6.3 0.0 2.5 2 1 0 2 2 2 0 Helix-hairpin-helix domain Pkinase PF00069.20 OAP61669.1 - 3.3e-70 236.1 0.0 5.2e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61669.1 - 1.2e-33 116.3 0.0 3.3e-33 114.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAP61669.1 - 0.0001 21.4 0.1 0.00024 20.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAP61669.1 - 0.0024 16.8 0.0 0.01 14.8 0.0 1.9 1 1 2 3 3 3 1 Kinase-like AAA PF00004.24 OAP61671.1 - 8.3e-16 58.3 0.0 2.5e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 OAP61671.1 - 5.5e-15 55.1 0.0 2.2e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 OAP61671.1 - 4.9e-13 49.0 0.0 1.6e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 OAP61671.1 - 1.1e-10 40.8 0.0 1.3e-07 30.7 0.0 2.1 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 OAP61671.1 - 1.2e-07 31.8 0.1 5.4e-07 29.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 OAP61671.1 - 1.5e-06 27.9 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 OAP61671.1 - 2e-06 27.4 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 OAP61671.1 - 2.2e-06 27.7 0.1 7.3e-05 22.8 0.0 2.7 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.7 OAP61671.1 - 6.4e-06 25.3 0.1 6.9e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 OAP61671.1 - 3.7e-05 23.3 0.0 9.6e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 OAP61671.1 - 4.6e-05 23.3 0.0 0.00088 19.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.1 OAP61671.1 - 5.8e-05 22.7 0.0 0.00024 20.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 OAP61671.1 - 6.5e-05 21.8 0.0 0.092 11.4 0.0 2.1 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 OAP61671.1 - 7.5e-05 22.4 0.2 0.00067 19.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 OAP61671.1 - 0.00045 19.2 0.0 0.0008 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 OAP61671.1 - 0.00084 18.9 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 OAP61671.1 - 0.0019 17.2 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 OAP61671.1 - 0.0028 17.2 0.1 0.015 14.8 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 OAP61671.1 - 0.003 17.0 0.1 0.028 13.8 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_10 PF12846.2 OAP61671.1 - 0.0033 16.9 0.1 1.5 8.1 0.0 2.3 1 1 1 2 2 2 2 AAA-like domain PhoH PF02562.11 OAP61671.1 - 0.0093 15.2 0.0 0.75 8.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 OAP61671.1 - 0.013 14.9 0.0 0.043 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 OAP61671.1 - 0.013 15.3 0.0 0.1 12.3 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 OAP61671.1 - 0.017 15.3 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 OAP61671.1 - 0.018 14.1 0.1 0.09 11.9 0.0 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAP61671.1 - 0.021 14.8 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TAFII28 PF04719.9 OAP61671.1 - 0.031 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region IstB_IS21 PF01695.12 OAP61671.1 - 0.082 12.3 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 OAP61671.1 - 0.094 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 OAP61671.1 - 0.13 13.1 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain P21-Arc PF04062.9 OAP61672.1 - 2e-80 268.6 0.0 2.3e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 OAP61672.1 - 0.066 13.2 0.2 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Pancreatic hormone peptide Gcd10p PF04189.8 OAP61673.1 - 4.3e-89 298.5 0.0 7e-89 297.8 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family HAD_2 PF13419.1 OAP61674.1 - 8.5e-10 39.1 0.0 2.5e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP61674.1 - 4.6e-08 32.6 0.0 7.6e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 OAP61674.1 - 0.0001 22.8 0.0 0.00013 22.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2627 PF11118.3 OAP61675.1 - 0.13 12.3 2.5 0.25 11.4 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) Rab5ip PF07019.7 OAP61675.1 - 0.32 11.1 3.4 0.44 10.7 2.3 1.4 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) YtpI PF14007.1 OAP61675.1 - 1.2 9.1 5.5 2.4 8.1 3.8 1.6 1 1 0 1 1 1 0 YtpI-like protein Mito_carr PF00153.22 OAP61676.1 - 2.1e-52 174.7 2.2 9.4e-18 63.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 OAP61676.1 - 0.075 12.8 0.4 0.26 11.1 0.2 1.9 2 0 0 2 2 2 0 UcrQ family HET PF06985.6 OAP61677.1 - 1.1e-23 83.9 0.1 2.3e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFO_IDH_MocA PF01408.17 OAP61678.1 - 1.8e-14 54.2 0.0 2.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans PF04082.13 OAP61679.1 - 1.2e-26 93.2 0.2 2.2e-26 92.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugarporin_N PF11471.3 OAP61679.1 - 0.48 10.0 3.8 1.3 8.7 1.1 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Abhydrolase_6 PF12697.2 OAP61680.1 - 1.9e-24 86.7 0.1 2.3e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP61680.1 - 3.2e-18 66.1 0.0 6e-17 61.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP61680.1 - 4.5e-12 45.9 0.0 1.6e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP61680.1 - 1.2e-05 24.8 0.1 0.064 12.6 0.0 3.1 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Ndr PF03096.9 OAP61680.1 - 5.4e-05 21.8 0.0 0.0018 16.7 0.0 2.0 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.16 OAP61680.1 - 0.0042 16.3 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 OAP61680.1 - 0.04 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 OAP61680.1 - 0.11 10.9 0.1 0.21 10.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 OAP61680.1 - 0.15 11.7 0.0 1.6 8.3 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FAD_binding_3 PF01494.14 OAP61681.1 - 6.6e-22 78.0 0.5 1.1e-21 77.3 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 OAP61681.1 - 2.6e-10 39.7 6.3 0.00027 19.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP61681.1 - 2.3e-07 30.7 3.1 5.7e-07 29.4 2.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAP61681.1 - 7.5e-07 29.4 2.6 7.7e-06 26.2 0.8 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP61681.1 - 1.8e-06 26.6 0.9 4.8e-06 25.2 0.6 1.6 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 OAP61681.1 - 1.4e-05 24.4 4.4 0.065 12.2 1.8 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 OAP61681.1 - 2.7e-05 24.1 3.6 0.00015 21.7 2.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP61681.1 - 3.5e-05 23.9 0.0 7.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP61681.1 - 3.9e-05 22.9 0.6 6e-05 22.2 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAP61681.1 - 0.0003 19.5 4.7 0.0022 16.6 2.5 2.4 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.19 OAP61681.1 - 0.00037 19.4 7.1 0.0008 18.3 4.9 1.5 1 0 0 1 1 1 1 FAD binding domain Rossmann-like PF10727.4 OAP61681.1 - 0.0038 16.9 0.4 0.009 15.7 0.2 1.7 1 0 0 1 1 1 1 Rossmann-like domain GIDA PF01134.17 OAP61681.1 - 0.0052 15.6 2.9 0.01 14.7 2.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 OAP61681.1 - 0.01 14.9 0.8 0.018 14.1 0.6 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 OAP61681.1 - 0.15 11.6 1.7 0.31 10.5 1.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 OAP61681.1 - 0.18 10.6 1.9 7.1 5.4 1.9 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 OAP61681.1 - 0.23 11.0 2.2 0.48 10.0 1.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 OAP61682.1 - 4.3e-31 107.9 23.6 4.3e-31 107.9 16.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF318 PF03773.8 OAP61682.1 - 0.0028 16.6 5.7 0.034 13.1 0.2 2.6 2 0 0 2 2 2 2 Predicted permease Aldedh PF00171.17 OAP61683.1 - 1.4e-147 491.7 0.1 1.6e-147 491.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 OAP61683.1 - 0.06 12.5 0.0 0.24 10.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) MFS_1 PF07690.11 OAP61684.1 - 1.7e-18 66.4 71.0 2e-14 53.0 30.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 OAP61685.1 - 3.3e-16 58.9 33.9 3.3e-16 58.9 23.5 3.1 1 1 1 3 3 3 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 OAP61686.1 - 2.3e-59 200.5 0.0 2.6e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DHHA1 PF02272.14 OAP61686.1 - 0.0081 15.8 0.2 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 DHHA1 domain Claudin_3 PF06653.6 OAP61686.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Epimerase PF01370.16 OAP61687.1 - 1.6e-05 24.4 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Helicase_C_3 PF13625.1 OAP61688.1 - 4.3e-26 91.1 0.0 1.1e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP61688.1 - 2.2e-14 53.7 0.0 4.5e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAP61688.1 - 7.4e-11 41.7 0.0 1.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAP61688.1 - 3.2e-09 36.0 0.1 5.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.1 OAP61688.1 - 0.00011 21.1 0.1 0.00019 20.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 AIF-MLS PF14962.1 OAP61689.1 - 0.00051 19.7 0.7 0.00088 18.9 0.5 1.6 1 1 0 1 1 1 1 Mitochondria Localisation Sequence CTD_bind PF04818.8 OAP61690.1 - 3e-10 40.1 0.1 3.4e-08 33.6 0.0 3.1 2 1 1 3 3 3 1 RNA polymerase II-binding domain. Peptidase_C48 PF02902.14 OAP61691.1 - 2e-33 115.8 0.1 3.7e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.13 OAP61692.1 - 2.4e-50 170.2 0.0 3.7e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Phage_B PF02304.10 OAP61692.1 - 0.11 12.8 0.1 0.29 11.4 0.0 1.7 2 0 0 2 2 2 0 Scaffold protein B BCDHK_Adom3 PF10436.4 OAP61693.1 - 3.6e-33 114.4 0.3 9.5e-33 113.0 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAP61693.1 - 1.1e-09 38.0 0.0 7.3e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 OAP61693.1 - 9.6e-05 22.1 0.0 0.056 13.2 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 OAP61693.1 - 0.00055 19.6 0.0 0.00094 18.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.3 OAP61694.1 - 4e-81 271.9 0.0 1.7e-80 269.8 0.0 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 OAP61694.1 - 4.8e-65 218.9 5.1 3.5e-64 216.1 0.5 3.6 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 OAP61694.1 - 8e-51 172.7 0.7 1.3e-50 171.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAP61694.1 - 1.7e-28 99.9 0.1 3.3e-28 98.9 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 OAP61694.1 - 5.9e-08 32.9 0.0 3.8e-06 27.1 0.0 3.0 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 OAP61694.1 - 0.00026 20.6 0.2 1.3 8.7 0.0 4.2 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like PspC PF04024.7 OAP61694.1 - 0.035 13.5 0.1 7.5 6.1 0.0 3.0 3 0 0 3 3 3 0 PspC domain NAD_binding_4 PF07993.7 OAP61695.1 - 9.5e-38 129.5 0.0 1.4e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 OAP61695.1 - 8.9e-28 96.8 0.0 1.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 OAP61695.1 - 1.5e-12 47.4 0.0 2.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 OAP61695.1 - 8.1e-07 29.2 0.1 1.7e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 OAP61695.1 - 0.00017 20.4 0.0 0.00038 19.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAP61695.1 - 0.075 11.9 0.0 0.33 9.7 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GH3 PF03321.8 OAP61695.1 - 0.42 9.0 0.0 0.67 8.4 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter DHQ_synthase PF01761.15 OAP61696.1 - 9.2e-54 182.0 0.0 1.4e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 OAP61696.1 - 9.9e-12 44.6 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.12 OAP61697.1 - 2.9e-14 52.6 0.0 4.8e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 OAP61697.1 - 1.6e-10 41.7 0.0 3.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 OAP61697.1 - 0.0093 15.2 0.0 0.026 13.8 0.0 1.7 1 1 0 1 1 1 1 Cephalosporin hydroxylase Cons_hypoth95 PF03602.10 OAP61697.1 - 0.053 12.9 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 OAP61697.1 - 0.055 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Corona_3 PF04694.7 OAP61697.1 - 0.059 13.2 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Coronavirus ORF3 protein ATP-grasp_4 PF13535.1 OAP61698.1 - 2.4e-07 30.6 0.0 3.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAP61698.1 - 7.6e-06 24.8 0.1 4.7e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Abhydrolase_3 PF07859.8 OAP61699.1 - 3.4e-28 98.6 0.1 4.9e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP61699.1 - 0.011 14.5 0.0 0.028 13.1 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family EMP24_GP25L PF01105.19 OAP61700.1 - 3.4e-46 157.2 0.6 3.9e-46 157.0 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD adh_short PF00106.20 OAP61701.1 - 1.6e-26 93.1 0.0 2.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP61701.1 - 3.9e-15 56.2 0.0 5.6e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP61701.1 - 6.5e-10 38.9 0.0 9.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP61701.1 - 7.2e-05 22.8 0.0 0.00013 22.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 OAP61701.1 - 7.5e-05 22.0 0.0 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 OAP61701.1 - 0.00098 18.6 0.0 0.0021 17.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 OAP61701.1 - 0.047 12.5 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 OAP61701.1 - 0.051 13.3 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DHHA2 PF02833.9 OAP61702.1 - 6.3e-11 42.5 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 OAP61702.1 - 1.1e-05 25.0 0.0 3.5e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 DHH family vMSA PF00695.14 OAP61702.1 - 0.13 11.4 0.6 0.18 10.9 0.4 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus CAP_N PF01213.14 OAP61702.1 - 2.6 7.2 4.7 4 6.6 2.3 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TGT PF01702.13 OAP61703.1 - 6.2e-45 153.3 0.0 9.2e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.12 OAP61704.1 - 4.7e-42 143.4 0.0 5.3e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase CPT PF07931.7 OAP61704.1 - 0.0013 18.3 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Resolvase PF00239.16 OAP61704.1 - 0.0014 18.5 0.0 0.0044 16.8 0.0 1.8 2 1 0 2 2 2 1 Resolvase, N terminal domain AAA_35 PF14516.1 OAP61704.1 - 0.012 14.3 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain KTI12 PF08433.5 OAP61704.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 OAP61704.1 - 0.023 14.6 0.0 0.031 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 OAP61704.1 - 0.03 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 OAP61704.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAP61704.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain GIY-YIG PF01541.19 OAP61705.1 - 1.4e-06 28.5 0.0 3.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain PHD PF00628.24 OAP61705.1 - 0.014 15.0 4.2 0.027 14.1 2.9 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 OAP61705.1 - 0.015 15.2 4.4 0.025 14.5 3.1 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 OAP61705.1 - 0.027 14.5 2.5 0.062 13.4 1.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 OAP61705.1 - 0.05 13.5 1.4 0.1 12.6 1.0 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Thioredoxin_2 PF13098.1 OAP61705.1 - 0.057 13.6 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain C1_1 PF00130.17 OAP61705.1 - 0.057 13.1 0.8 0.057 13.1 0.5 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 OAP61705.1 - 0.065 13.0 6.6 0.12 12.2 4.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C4_Topoisom PF01396.14 OAP61705.1 - 0.31 10.5 1.9 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Prok-RING_1 PF14446.1 OAP61705.1 - 1.3 8.8 7.0 0.26 11.0 1.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PLU-1 PF08429.6 OAP61706.1 - 7.8e-83 278.1 14.2 8.7e-81 271.4 8.4 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 OAP61706.1 - 2.2e-43 147.1 0.2 5e-43 145.9 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 OAP61706.1 - 9.5e-26 89.4 0.1 2.5e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 OAP61706.1 - 1.6e-16 59.5 0.7 3.8e-16 58.2 0.5 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 OAP61706.1 - 6.5e-14 51.7 6.6 1.9e-13 50.2 4.6 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 OAP61706.1 - 2.9e-13 49.2 39.7 2.1e-08 33.6 7.6 3.5 3 0 0 3 3 3 2 PHD-finger Prok-RING_1 PF14446.1 OAP61706.1 - 9.1e-05 22.1 5.1 9.1e-05 22.1 3.6 2.9 2 1 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 OAP61706.1 - 0.023 14.0 10.2 0.068 12.4 1.7 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 OAP61706.1 - 0.68 9.3 19.5 0.041 13.2 4.5 2.9 2 0 0 2 2 2 0 PHD-finger zf-RanBP PF00641.13 OAP61706.1 - 0.76 8.9 9.1 1.6 7.8 0.3 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others MTHFR PF02219.12 OAP61707.1 - 2.4e-92 309.0 0.0 6.2e-92 307.7 0.0 1.6 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase Abhydrolase_3 PF07859.8 OAP61708.1 - 2.8e-59 200.2 0.0 3.6e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP61708.1 - 3.5e-11 42.5 0.2 1e-10 41.0 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 OAP61708.1 - 8.3e-06 25.1 0.0 0.068 12.3 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP61708.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 OAP61708.1 - 0.034 13.4 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Pyr_redox_3 PF13738.1 OAP61709.1 - 7.6e-21 75.1 0.0 1.6e-20 74.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP61709.1 - 5.3e-13 48.0 0.2 2.4e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP61709.1 - 7e-11 42.3 0.0 6.2e-09 36.0 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP61709.1 - 9.3e-10 38.3 0.3 3.1e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP61709.1 - 8.3e-09 34.8 0.0 2.2e-07 30.1 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 OAP61709.1 - 0.00023 21.5 0.2 0.21 12.0 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP61709.1 - 0.00058 19.6 4.4 0.0054 16.5 0.3 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 OAP61709.1 - 0.0015 17.7 0.0 0.027 13.6 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP61709.1 - 0.006 16.8 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.19 OAP61709.1 - 0.03 13.2 0.0 0.21 10.4 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP61709.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain SnoaL_4 PF13577.1 OAP61710.1 - 1.6e-20 73.3 0.4 2e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.13 OAP61710.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Sugar_tr PF00083.19 OAP61711.1 - 8.9e-62 209.1 31.2 1.1e-61 208.8 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61711.1 - 6.8e-22 77.6 31.0 6.8e-22 77.6 21.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 OAP61712.1 - 2e-30 105.9 1.9 2.5e-30 105.6 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP61712.1 - 8.5e-29 101.0 0.1 1e-28 100.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP61712.1 - 3.1e-10 40.0 0.7 4.7e-10 39.4 0.5 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 OAP61712.1 - 0.022 15.1 0.5 0.047 14.0 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 OAP61712.1 - 0.061 12.2 0.3 0.094 11.6 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pyr_redox_3 PF13738.1 OAP61713.1 - 1.3e-21 77.6 0.1 5.2e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP61713.1 - 8.2e-15 53.9 1.0 7.6e-12 44.1 0.7 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP61713.1 - 2.1e-09 37.2 0.0 4.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP61713.1 - 1.9e-08 34.4 0.0 1.1e-06 28.6 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP61713.1 - 4.4e-07 29.1 0.6 0.069 12.0 0.0 3.8 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP61713.1 - 0.00015 21.5 0.1 0.0035 17.1 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 OAP61713.1 - 0.0021 17.0 0.0 0.42 9.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 OAP61713.1 - 0.0028 17.2 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 OAP61713.1 - 0.017 15.2 0.0 8.1 6.5 0.0 3.3 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 OAP61713.1 - 0.049 12.4 0.1 6.3 5.5 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Fib_alpha PF08702.5 OAP61714.1 - 0.0097 16.0 0.2 0.031 14.4 0.2 1.7 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family DALR_1 PF05746.10 OAP61714.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 DALR anticodon binding domain DUF1212 PF06738.7 OAP61714.1 - 0.039 13.4 0.3 0.047 13.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) BRCA-2_OB3 PF09104.5 OAP61714.1 - 0.089 12.6 0.2 0.13 12.0 0.1 1.3 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Fungal_trans PF04082.13 OAP61715.1 - 3.7e-19 68.6 0.5 5.6e-19 68.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ycf66_N PF07444.6 OAP61715.1 - 0.059 13.0 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ycf66 protein N-terminus Abhydrolase_3 PF07859.8 OAP61716.1 - 3.7e-58 196.5 0.0 4.7e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP61716.1 - 4.4e-05 22.3 0.1 0.00021 20.1 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 OAP61716.1 - 0.0013 17.9 0.0 0.0085 15.3 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family ADH_N PF08240.7 OAP61717.1 - 7.3e-22 77.1 0.2 1.3e-21 76.4 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP61717.1 - 9.5e-21 73.7 0.1 1.5e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP61717.1 - 0.0001 21.8 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 OAP61717.1 - 0.00011 22.1 0.3 0.0002 21.3 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 OAP61717.1 - 0.00016 20.9 0.0 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 OAP61717.1 - 0.0042 17.5 0.2 0.0091 16.4 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAP61717.1 - 0.0062 15.6 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase 3HCDH_N PF02737.13 OAP61717.1 - 0.019 14.6 0.3 0.029 14.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 OAP61717.1 - 0.02 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 OAP61717.1 - 0.033 14.0 0.5 0.068 12.9 0.2 1.6 2 0 0 2 2 2 0 ThiF family GFO_IDH_MocA PF01408.17 OAP61717.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SnoaL_4 PF13577.1 OAP61718.1 - 9.8e-15 54.5 0.4 1.4e-14 54.0 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain ATP_synth_reg PF14960.1 OAP61718.1 - 0.34 10.1 1.5 1.2 8.3 0.1 2.3 2 0 0 2 2 2 0 ATP synthase regulation Fungal_trans PF04082.13 OAP61719.1 - 1.2e-06 27.6 1.7 3.8e-06 25.9 1.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_2 PF12681.2 OAP61720.1 - 0.0013 19.3 0.0 0.16 12.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 OAP61720.1 - 0.021 14.8 0.0 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.13 OAP61721.1 - 1.6e-17 63.2 0.2 2.3e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61721.1 - 6.1e-05 22.8 20.2 6.6e-05 22.7 11.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OrfB_Zn_ribbon PF07282.6 OAP61721.1 - 0.5 10.0 12.7 2.7 7.7 8.0 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain HpcH_HpaI PF03328.9 OAP61722.1 - 3.1e-31 107.9 0.0 3.7e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEPcase_2 PF14010.1 OAP61722.1 - 0.022 13.0 0.0 0.033 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Cyclase PF04199.8 OAP61723.1 - 4.9e-14 52.3 0.0 6.9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 OAP61724.1 - 4.5e-73 246.3 20.9 5.4e-73 246.0 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61724.1 - 1.9e-20 72.8 38.1 8.2e-16 57.6 16.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.11 OAP61725.1 - 9.6e-44 149.9 0.2 1.1e-43 149.7 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pyr_redox_3 PF13738.1 OAP61726.1 - 2.3e-20 73.5 0.0 3.6e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP61726.1 - 5.1e-18 64.5 0.1 5e-16 58.0 0.1 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP61726.1 - 2.2e-08 33.9 0.2 6.2e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP61726.1 - 5.4e-06 26.4 0.0 1.1e-05 25.4 0.0 1.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP61726.1 - 1.1e-05 24.4 0.0 0.0013 17.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 OAP61726.1 - 0.13 12.3 0.0 1.1e+02 2.9 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 OAP61726.1 - 0.38 9.1 0.8 0.8 8.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein adh_short_C2 PF13561.1 OAP61727.1 - 1.3e-27 97.1 1.4 1.5e-27 96.9 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP61727.1 - 5.9e-26 91.3 8.0 8.5e-26 90.8 5.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61727.1 - 1.9e-10 40.6 5.3 2.7e-10 40.1 3.7 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 OAP61727.1 - 0.00047 19.9 2.2 0.00048 19.9 0.2 1.9 2 1 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 OAP61727.1 - 0.0016 17.8 0.3 0.0054 16.1 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAP61727.1 - 0.01 15.4 0.5 0.021 14.4 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 OAP61727.1 - 0.039 12.8 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAP61727.1 - 0.043 13.8 0.4 0.043 13.8 0.3 1.7 2 0 0 2 2 2 0 NADH(P)-binding ApbA PF02558.11 OAP61727.1 - 0.054 12.9 0.9 0.18 11.2 0.2 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 OAP61727.1 - 0.062 12.6 0.1 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DapB_N PF01113.15 OAP61727.1 - 0.41 10.5 3.6 1.4 8.8 0.2 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus p450 PF00067.17 OAP61728.1 - 1.7e-63 214.7 0.0 2.1e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMN_dh PF01070.13 OAP61729.1 - 1.9e-99 332.9 0.0 3e-99 332.2 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase adh_short PF00106.20 OAP61729.1 - 1.1e-23 84.0 0.4 2e-23 83.1 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Cyt-b5 PF00173.23 OAP61729.1 - 1.3e-23 82.6 0.0 2.3e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain adh_short_C2 PF13561.1 OAP61729.1 - 5.9e-08 32.7 0.1 9.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NMO PF03060.10 OAP61729.1 - 6.7e-06 25.4 0.0 1.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAP61729.1 - 0.00026 19.9 0.1 0.00068 18.6 0.0 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain KR PF08659.5 OAP61729.1 - 0.00042 20.0 0.7 0.0012 18.5 0.5 1.7 1 1 0 1 1 1 1 KR domain Glu_synthase PF01645.12 OAP61729.1 - 0.0059 15.5 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Epimerase PF01370.16 OAP61729.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 OAP61730.1 - 6e-20 71.2 0.7 8.9e-20 70.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61730.1 - 0.00017 21.4 7.1 0.00032 20.5 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.22 OAP61731.1 - 3.1e-06 26.9 4.8 9.5e-06 25.3 3.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP61731.1 - 0.00018 21.1 0.2 0.00046 19.7 0.0 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain adh_short_C2 PF13561.1 OAP61732.1 - 2.8e-17 63.3 0.0 3.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP61732.1 - 2.3e-15 56.9 0.5 3.1e-15 56.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF3638 PF12340.3 OAP61733.1 - 1.4e-69 233.6 0.0 2.5e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 OAP61733.1 - 1.3e-11 43.4 0.2 3.2e-11 42.1 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Herpes_BMRF2 PF04633.7 OAP61733.1 - 0.31 9.9 0.3 0.51 9.2 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein CRISPR_Cse2 PF09485.5 OAP61734.1 - 0.00092 19.2 0.9 0.0014 18.7 0.6 1.2 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) HSP9_HSP12 PF04119.7 OAP61734.1 - 0.021 14.8 0.1 0.069 13.2 0.1 1.8 1 0 0 1 1 1 0 Heat shock protein 9/12 Hex_IIIa PF02455.11 OAP61734.1 - 0.04 12.6 4.1 0.055 12.1 2.8 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Dehydrin PF00257.14 OAP61734.1 - 0.2 11.9 9.3 0.29 11.4 6.5 1.4 1 1 0 1 1 1 0 Dehydrin AIG2 PF06094.7 OAP61736.1 - 5e-16 59.0 0.1 8.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Septin PF00735.13 OAP61737.1 - 3.2e-115 384.0 0.3 4.7e-115 383.4 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 OAP61737.1 - 5.7e-07 29.5 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAP61737.1 - 4.2e-06 26.3 0.1 5e-05 22.8 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 OAP61737.1 - 1.1e-05 24.6 0.0 2.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAP61737.1 - 0.0027 17.8 0.5 0.0087 16.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 OAP61737.1 - 0.0028 18.1 0.5 0.0086 16.5 0.1 2.1 2 0 0 2 2 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 OAP61737.1 - 0.0042 16.5 0.0 0.013 14.9 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.1 OAP61737.1 - 0.0048 16.5 0.1 0.0098 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 OAP61737.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 OAP61737.1 - 0.0066 15.2 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 OAP61737.1 - 0.0088 15.3 0.1 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein Ras PF00071.17 OAP61737.1 - 0.014 14.7 0.2 0.056 12.8 0.1 2.0 2 0 0 2 2 2 0 Ras family NACHT PF05729.7 OAP61737.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 OAP61737.1 - 0.024 13.5 0.2 0.067 12.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 OAP61737.1 - 0.032 14.0 5.5 0.4 10.5 0.0 3.0 2 1 1 3 3 3 0 Dynamin family ABC_tran PF00005.22 OAP61737.1 - 0.045 14.0 0.1 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 OAP61737.1 - 0.048 13.1 0.3 2.2 7.7 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 OAP61737.1 - 0.051 13.5 1.2 0.69 9.8 0.0 2.7 2 1 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.21 OAP61737.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 OAP61737.1 - 0.083 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ArgK PF03308.11 OAP61737.1 - 0.091 11.5 1.4 0.94 8.1 0.0 2.7 3 0 0 3 3 3 0 ArgK protein ATP_bind_1 PF03029.12 OAP61737.1 - 0.17 11.4 0.5 8.7 5.8 0.1 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 OAP61737.1 - 0.25 10.2 2.8 0.37 9.7 1.9 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.1 OAP61737.1 - 6.9 6.9 17.1 1.6e+02 2.4 11.9 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 OAP61738.1 - 2.5e-46 153.9 34.6 6.4e-12 44.8 0.2 12.5 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 OAP61738.1 - 6.1e-20 71.1 0.0 9.6e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Coatomer_WDAD PF04053.9 OAP61738.1 - 0.21 10.3 0.0 15 4.2 0.0 2.5 2 1 0 2 2 2 0 Coatomer WD associated region MFS_1 PF07690.11 OAP61739.1 - 2.2e-26 92.4 40.8 2.2e-26 92.4 28.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 OAP61739.1 - 4.7 5.8 8.3 1.7 7.3 0.3 2.5 2 0 0 2 2 2 0 MMPL family RskA PF10099.4 OAP61739.1 - 7.5 6.2 6.5 6.3 6.4 0.2 3.2 4 0 0 4 4 4 0 Anti-sigma-K factor rskA Methyltransf_32 PF13679.1 OAP61740.1 - 4.9e-21 74.8 2.8 4.9e-21 74.8 1.9 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP61740.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61740.1 - 0.13 12.8 0.0 0.39 11.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NUDIX PF00293.23 OAP61741.1 - 2.3e-15 56.4 0.1 4.1e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 OAP61741.1 - 3.2e-10 40.2 0.0 6.9e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 OAP61741.1 - 1.2e-07 31.0 2.2 2.2e-07 30.2 1.5 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain CN_hydrolase PF00795.17 OAP61742.1 - 2e-25 89.2 0.0 3.1e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 OAP61742.1 - 7.7e-24 83.9 0.0 4.6e-23 81.3 0.0 1.9 1 1 0 1 1 1 1 NAD synthase GTP_cyclohydroI PF01227.17 OAP61743.1 - 1e-73 246.4 0.1 2.3e-73 245.3 0.1 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase I QueF PF14489.1 OAP61743.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein Abhydrolase_6 PF12697.2 OAP61744.1 - 8.9e-22 78.0 0.0 1.1e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP61744.1 - 3.3e-07 30.1 0.0 5.2e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP61744.1 - 0.16 11.5 0.0 0.54 9.7 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Ubie_methyltran PF01209.13 OAP61745.1 - 2.9e-16 59.3 0.0 8.1e-16 57.8 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 OAP61745.1 - 4.1e-15 56.0 0.0 8.5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP61745.1 - 4.1e-10 39.4 0.0 5.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP61745.1 - 1.5e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP61745.1 - 1.7e-07 31.6 0.0 3.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP61745.1 - 3.3e-07 30.3 0.0 8.6e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP61745.1 - 4.2e-06 27.0 0.0 1.1e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61745.1 - 3e-05 24.5 0.0 6.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Transglut_core PF01841.14 OAP61746.1 - 3.4e-10 40.1 0.0 7.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily HET PF06985.6 OAP61747.1 - 0.063 13.4 4.5 0.25 11.4 3.1 1.9 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) SpoIIAA-like PF11964.3 OAP61747.1 - 0.081 13.2 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 SpoIIAA-like MFS_1 PF07690.11 OAP61748.1 - 1.3e-35 122.7 25.7 3.5e-35 121.3 17.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily 5TM-5TMR_LYT PF07694.7 OAP61748.1 - 0.32 10.3 10.3 0.53 9.6 0.0 3.2 4 1 0 4 4 4 0 5TMR of 5TMR-LYT SDA1 PF05285.7 OAP61749.1 - 2.3 7.3 15.0 3.4 6.8 10.4 1.2 1 0 0 1 1 1 0 SDA1 adh_short PF00106.20 OAP61750.1 - 1.6e-23 83.4 0.2 2.3e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAP61750.1 - 3.4e-09 36.0 0.1 4.6e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 OAP61750.1 - 8.4e-09 35.3 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 OAP61750.1 - 8.1e-05 21.7 0.3 0.00013 21.1 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Methyltransf_25 PF13649.1 OAP61750.1 - 0.00058 20.1 0.0 0.0018 18.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 OAP61750.1 - 0.0012 17.6 0.3 0.0017 17.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP61750.1 - 0.002 17.5 1.1 0.022 14.2 0.7 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAP61750.1 - 0.0032 17.5 0.3 0.0062 16.6 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAP61750.1 - 0.014 15.6 1.0 0.026 14.7 0.2 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 OAP61750.1 - 0.02 14.6 0.4 0.035 13.9 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 OAP61750.1 - 0.02 15.4 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Urocanase PF01175.13 OAP61750.1 - 0.044 11.8 0.1 0.069 11.1 0.1 1.3 1 0 0 1 1 1 0 Urocanase F420_oxidored PF03807.12 OAP61750.1 - 0.062 13.7 0.8 0.1 13.0 0.2 1.7 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAP61750.1 - 0.073 12.7 0.5 0.12 12.0 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 OAP61750.1 - 0.082 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.1 OAP61750.1 - 0.14 12.1 1.2 0.23 11.4 0.9 1.5 1 1 0 1 1 1 0 NADH(P)-binding ELFV_dehydrog PF00208.16 OAP61750.1 - 0.22 11.0 4.2 2.1 7.8 0.4 2.1 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.20 OAP61751.1 - 1.6e-16 60.6 1.0 3.1e-16 59.7 0.2 1.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP61751.1 - 5.2e-11 42.7 0.0 1.6e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAP61751.1 - 0.0054 16.7 0.3 0.015 15.2 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAP61751.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP61751.1 - 0.014 14.7 0.1 0.04 13.3 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.5 OAP61751.1 - 0.022 14.4 0.1 0.85 9.2 0.1 2.4 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 OAP61752.1 - 4.1e-28 98.3 1.5 5.2e-28 98.0 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP61752.1 - 1.5e-26 93.6 0.3 1.8e-26 93.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP61752.1 - 5e-12 45.8 1.4 6.9e-12 45.3 1.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP61752.1 - 0.056 12.8 0.2 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GST_N_3 PF13417.1 OAP61753.1 - 3.2e-17 62.4 0.0 6.1e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP61753.1 - 4.1e-14 52.3 0.0 5.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAP61753.1 - 8.4e-14 51.5 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP61753.1 - 2.1e-13 50.0 0.0 3.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP61753.1 - 8.8e-09 35.1 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP61753.1 - 1.1e-06 29.0 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 OAP61754.1 - 3.6e-24 85.1 27.9 3.6e-24 85.1 19.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP61754.1 - 7.3e-09 34.7 12.0 7.3e-09 34.7 8.3 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter GCS PF03074.11 OAP61755.1 - 1.7e-104 349.8 0.0 2.1e-104 349.5 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 OAP61755.1 - 0.00049 19.3 0.0 0.00084 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) 2OG-FeII_Oxy_3 PF13640.1 OAP61756.1 - 0.029 14.8 0.0 0.049 14.1 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 OAP61756.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase PhyH PF05721.8 OAP61757.1 - 8.8e-20 71.6 0.0 1.1e-19 71.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.3 OAP61758.1 - 5.9e-51 173.2 0.8 7.6e-51 172.8 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 OAP61759.1 - 4.8e-33 111.8 13.8 7.6e-10 38.2 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ PF01011.16 OAP61759.1 - 0.0001 21.6 0.0 0.035 13.6 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat BBS2_Mid PF14783.1 OAP61759.1 - 0.0015 18.3 0.3 0.38 10.5 0.1 4.2 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 OAP61759.1 - 0.0026 17.2 1.9 0.035 13.5 0.4 2.0 1 1 0 1 1 1 1 PQQ-like domain NUMOD4 PF07463.6 OAP61759.1 - 0.0086 15.9 2.0 4.9 7.1 0.1 3.1 3 0 0 3 3 3 2 NUMOD4 motif PQQ_3 PF13570.1 OAP61759.1 - 3 8.2 15.4 0.41 10.9 0.1 5.2 5 1 1 6 6 6 0 PQQ-like domain ACT_7 PF13840.1 OAP61760.1 - 3.2e-26 90.6 0.0 2.4e-16 59.0 0.0 3.6 3 0 0 3 3 3 3 ACT domain XRN_N PF03159.13 OAP61761.1 - 6.6e-104 346.4 0.0 6.6e-104 346.4 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF1789 PF08748.6 OAP61761.1 - 0.031 14.3 1.0 0.089 12.8 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) R3H PF01424.17 OAP61761.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 R3H domain WD40 PF00400.27 OAP61762.1 - 1.9e-41 138.5 3.4 6.2e-09 35.3 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 OAP61762.1 - 1.9e-29 101.3 0.3 4.6e-29 100.1 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 OAP61762.1 - 0.011 13.9 0.5 3.6 5.6 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Fungal_trans_2 PF11951.3 OAP61763.1 - 1.1e-11 44.0 0.6 1.7e-11 43.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61763.1 - 2.2e-05 24.2 8.7 3.5e-05 23.6 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 OAP61764.1 - 2.9e-10 39.8 0.0 5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP61764.1 - 1e-08 34.7 0.0 1.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1546 PF07571.8 OAP61765.1 - 3.9e-32 110.2 0.0 7.5e-32 109.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 OAP61765.1 - 2.8e-24 84.8 0.1 7e-24 83.5 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 OAP61765.1 - 0.003 17.5 0.1 0.012 15.6 0.0 2.1 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAP61765.1 - 0.0032 17.5 0.0 0.0078 16.3 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Rifin_STEVOR PF02009.11 OAP61766.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family TMEM51 PF15345.1 OAP61766.1 - 0.033 13.8 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DAP10 PF07213.6 OAP61766.1 - 0.058 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 DAP10 membrane protein MGC-24 PF05283.6 OAP61766.1 - 0.064 13.0 7.8 0.091 12.5 5.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF1191 PF06697.7 OAP61766.1 - 0.11 11.2 0.1 0.21 10.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) MAGE_N PF12440.3 OAP61766.1 - 3.5 7.9 7.5 8.5 6.7 5.2 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal PRT_C PF08372.5 OAP61768.1 - 0.02 14.4 3.1 0.061 12.8 0.0 2.5 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Fungal_trans_2 PF11951.3 OAP61769.1 - 3.9e-07 29.0 0.0 6.8e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RmlD_sub_bind PF04321.12 OAP61770.1 - 6.5e-58 195.8 0.0 7.7e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 OAP61770.1 - 4.6e-27 94.9 0.0 5.9e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP61770.1 - 3.3e-12 45.8 0.1 1.4e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 OAP61770.1 - 1.4e-11 43.6 0.1 1.6e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAP61770.1 - 2.1e-11 43.2 1.3 2.5e-09 36.4 0.2 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAP61770.1 - 2e-06 27.9 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAP61770.1 - 1.7e-05 24.7 0.5 0.018 14.9 0.0 2.5 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.5 OAP61770.1 - 0.0018 17.9 0.2 0.17 11.5 0.0 2.3 2 0 0 2 2 2 1 KR domain SET PF00856.23 OAP61771.1 - 8e-14 52.2 0.1 7.9e-13 49.0 0.1 2.8 1 1 0 1 1 1 1 SET domain Pil1 PF13805.1 OAP61772.1 - 1.5e-155 516.1 0.1 2e-155 515.8 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 OAP61772.1 - 0.011 15.1 2.4 0.014 14.7 0.7 1.7 1 1 1 2 2 2 0 FAM92 protein SUR7 PF06687.7 OAP61773.1 - 5e-36 124.2 14.8 6.1e-36 123.9 10.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Wzy_C PF04932.10 OAP61773.1 - 0.13 12.0 6.2 0.98 9.1 2.5 2.3 2 0 0 2 2 2 0 O-Antigen ligase LigD_N PF13298.1 OAP61774.1 - 1.3e-24 86.3 0.1 5e-24 84.4 0.1 1.9 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) Pirin PF02678.11 OAP61775.1 - 1e-21 76.8 1.3 3.8e-21 74.9 0.9 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 OAP61775.1 - 1.9e-07 30.4 3.5 2e-05 23.9 0.8 3.1 2 1 0 2 2 2 2 Cupin domain MelC1 PF06236.6 OAP61775.1 - 0.029 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 ABC_tran PF00005.22 OAP61776.1 - 1.3e-48 164.7 0.1 2.3e-29 102.4 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 OAP61776.1 - 1.9e-27 96.4 26.0 2.8e-17 63.0 9.3 4.2 5 1 1 6 6 4 2 ABC transporter transmembrane region SMC_N PF02463.14 OAP61776.1 - 2.1e-11 43.4 0.8 3e-05 23.3 0.1 4.6 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAP61776.1 - 2.1e-05 24.5 0.2 0.031 14.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 OAP61776.1 - 3.9e-05 23.1 0.0 0.085 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 OAP61776.1 - 3.9e-05 24.0 1.0 0.018 15.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 OAP61776.1 - 0.00018 20.9 0.4 0.78 9.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 OAP61776.1 - 0.00021 20.8 0.1 0.56 9.5 0.0 2.9 2 1 0 3 3 3 2 AAA-like domain T2SE PF00437.15 OAP61776.1 - 0.001 18.0 0.0 0.2 10.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 OAP61776.1 - 0.0012 18.7 0.0 0.3 11.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAP61776.1 - 0.0013 17.9 0.0 1.7 7.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 OAP61776.1 - 0.0038 17.2 1.8 0.7 9.8 0.1 3.9 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 OAP61776.1 - 0.0053 16.8 0.2 11 6.1 0.0 3.6 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 OAP61776.1 - 0.0063 16.3 3.3 0.8 9.4 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 Miro PF08477.8 OAP61776.1 - 0.012 16.1 0.0 3.7 8.0 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 OAP61776.1 - 0.012 15.0 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 OAP61776.1 - 0.018 14.9 0.1 3.5 7.6 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 OAP61776.1 - 0.028 14.1 0.1 1.2 8.9 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain ATG27 PF09451.5 OAP61776.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein 27 Peptidase_M28 PF04389.12 OAP61777.1 - 6.9e-34 117.1 0.0 9.6e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Mitofilin PF09731.4 OAP61779.1 - 1.6 7.2 22.2 2.1 6.8 15.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MutS_V PF00488.16 OAP61780.1 - 1.2e-77 260.4 0.0 2.1e-77 259.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAP61780.1 - 5.3e-51 173.3 0.0 1e-50 172.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 OAP61780.1 - 3.4e-33 114.0 0.1 1e-32 112.5 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 OAP61780.1 - 7.4e-15 55.2 0.0 1.8e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 OAP61780.1 - 3.3e-07 30.3 0.0 1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV SPT6_acidic PF14632.1 OAP61780.1 - 0.00065 19.8 5.5 0.00065 19.8 3.8 2.7 3 0 0 3 3 3 1 Acidic N-terminal SPT6 AAA_23 PF13476.1 OAP61780.1 - 0.0066 16.7 0.0 0.0066 16.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 OAP61780.1 - 0.013 15.0 0.1 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 OAP61780.1 - 0.03 14.3 0.3 0.32 10.9 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 OAP61780.1 - 0.12 12.2 0.5 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.20 OAP61781.1 - 3.5e-73 246.2 0.0 4.7e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 OAP61781.1 - 0.027 13.9 0.0 0.093 12.1 0.0 1.9 1 0 0 1 1 1 0 S4 domain Zn_clus PF00172.13 OAP61783.1 - 9.5e-06 25.4 8.7 2.4e-05 24.1 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN9 PF10680.4 OAP61784.1 - 8.6e-12 44.6 0.3 4.2e-11 42.4 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Zn_clus PF00172.13 OAP61784.1 - 0.032 14.1 7.0 0.083 12.8 4.8 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PALP PF00291.20 OAP61785.1 - 8.7e-70 235.3 0.1 1.3e-69 234.8 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 OAP61785.1 - 5.2e-46 154.1 0.0 6.6e-23 80.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 OAP61786.1 - 3.1e-23 81.2 0.2 4.4e-23 80.7 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region FTCD_C PF04961.7 OAP61786.1 - 0.059 12.7 3.4 0.1 12.0 2.0 1.6 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase MAS20 PF02064.10 OAP61786.1 - 0.63 9.9 4.4 0.36 10.7 1.5 1.8 2 1 0 2 2 2 0 MAS20 protein import receptor Nup88 PF10168.4 OAP61786.1 - 0.69 7.6 5.5 0.88 7.3 3.8 1.0 1 0 0 1 1 1 0 Nuclear pore component V_ATPase_I PF01496.14 OAP61786.1 - 0.71 7.6 3.2 0.88 7.3 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAP7 PF05672.6 OAP61786.1 - 0.91 8.8 21.0 1.4 8.2 14.6 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF2681 PF10883.3 OAP61786.1 - 2 8.6 5.3 0.79 9.9 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Phage_Gp23 PF10669.4 OAP61786.1 - 3.7 7.6 7.8 8.2 6.5 5.4 1.6 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Complex1_LYR PF05347.10 OAP61787.1 - 5.1e-11 42.1 0.5 2e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAP61787.1 - 9.3e-11 41.7 0.5 4.1e-10 39.7 0.0 2.4 3 0 0 3 3 3 1 Complex1_LYR-like zf-C3HC4 PF00097.20 OAP61787.1 - 0.00033 20.2 3.9 0.00064 19.3 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP61787.1 - 0.00043 19.8 4.9 0.00075 19.1 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP61787.1 - 0.01 15.8 7.1 0.019 14.9 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP61787.1 - 0.039 13.7 4.7 0.075 12.8 3.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 OAP61787.1 - 0.077 12.7 2.4 0.19 11.4 1.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 OAP61787.1 - 0.46 10.2 6.8 1.8 8.3 4.9 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAP61787.1 - 5 7.0 9.0 9.3 6.2 6.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1223 PF06764.6 OAP61788.1 - 0.11 12.2 0.9 0.18 11.5 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) RCC_reductase PF06405.6 OAP61788.1 - 0.26 10.2 0.0 0.26 10.2 0.0 1.5 2 0 0 2 2 2 0 Red chlorophyll catabolite reductase (RCC reductase) Pyr_redox_3 PF13738.1 OAP61789.1 - 4.3e-20 72.6 0.0 6.8e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP61789.1 - 1.8e-13 49.5 0.2 3.8e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP61789.1 - 9.3e-11 41.9 0.0 1.7e-08 34.5 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP61789.1 - 5.5e-10 38.6 0.0 2e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP61789.1 - 1.1e-09 38.1 0.0 2.4e-08 33.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP61789.1 - 1.1e-06 27.8 0.4 0.0032 16.4 0.0 3.5 3 2 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 OAP61789.1 - 0.00022 20.4 0.2 0.00053 19.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 OAP61789.1 - 0.00048 19.0 0.0 0.0012 17.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAP61789.1 - 0.0041 16.0 0.0 0.026 13.4 0.0 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 OAP61789.1 - 0.097 11.1 0.2 4.8 5.5 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.22 OAP61789.1 - 0.11 12.8 0.2 5.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP61789.1 - 0.13 12.3 0.0 27 4.8 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 OAP61789.1 - 0.18 11.5 2.4 14 5.3 0.1 3.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 OAP61789.1 - 1.8 7.3 4.3 3.1 6.5 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A WD40 PF00400.27 OAP61791.1 - 7.7e-31 104.8 15.2 4.3e-08 32.7 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 OAP61791.1 - 0.034 13.8 0.0 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Tom37_C PF11801.3 OAP61792.1 - 2.8e-34 118.3 0.0 4e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 OAP61792.1 - 3.5e-25 88.0 0.4 3.9e-24 84.6 0.0 2.7 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 OAP61792.1 - 4e-06 26.6 0.3 2e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAP61792.1 - 0.0022 17.9 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP61792.1 - 0.0085 16.5 0.2 0.038 14.4 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP61792.1 - 0.028 14.6 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Zip PF02535.17 OAP61793.1 - 1.1e-58 198.7 5.8 1.3e-58 198.4 4.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter COX7C PF02935.11 OAP61793.1 - 0.22 11.3 2.2 2.3 8.0 0.0 3.3 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc bZIP_1 PF00170.16 OAP61794.1 - 2.1e-05 24.4 13.3 0.00031 20.6 2.8 2.3 1 1 1 2 2 2 2 bZIP transcription factor GAS PF13851.1 OAP61794.1 - 0.014 14.5 1.2 0.021 14.0 0.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 OAP61794.1 - 0.021 15.1 0.3 0.031 14.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 OAP61794.1 - 0.087 12.6 14.0 0.43 10.4 1.8 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DUF904 PF06005.7 OAP61794.1 - 0.17 12.2 2.4 0.29 11.4 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Fmp27_WPPW PF10359.4 OAP61794.1 - 0.18 10.1 1.4 0.24 9.7 1.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mnd1 PF03962.10 OAP61794.1 - 0.23 11.1 5.8 0.32 10.6 4.0 1.1 1 0 0 1 1 1 0 Mnd1 family HAUS6_N PF14661.1 OAP61794.1 - 0.45 9.8 3.7 0.64 9.3 2.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HALZ PF02183.13 OAP61794.1 - 0.49 10.1 3.3 0.93 9.2 2.3 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper APG6 PF04111.7 OAP61794.1 - 0.62 9.0 3.9 0.84 8.6 2.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NYD-SP28_assoc PF14775.1 OAP61794.1 - 0.71 9.6 2.5 1.3 8.7 1.7 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain ADIP PF11559.3 OAP61794.1 - 0.83 9.5 6.7 1.2 8.9 4.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Methyltransf_31 PF13847.1 OAP61795.1 - 5.6e-27 94.1 0.0 7.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP61795.1 - 6.1e-20 71.5 0.0 1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61795.1 - 2.6e-14 53.7 0.0 4.9e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP61795.1 - 8.6e-13 48.5 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP61795.1 - 1.5e-12 47.5 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP61795.1 - 2.3e-11 44.0 0.0 3.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP61795.1 - 8.8e-10 38.6 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP61795.1 - 1.4e-08 34.1 0.0 1.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 OAP61795.1 - 3.2e-05 23.5 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 OAP61795.1 - 3.7e-05 22.9 0.0 5.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 OAP61795.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 OAP61795.1 - 0.0027 17.3 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.15 OAP61795.1 - 0.016 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 OAP61795.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GTP_CH_N PF12471.3 OAP61796.1 - 1.4e-91 305.3 0.0 2.3e-91 304.7 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 OAP61796.1 - 3.7e-18 65.3 0.0 7.1e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.16 OAP61796.1 - 0.04 13.3 0.0 1.6 8.1 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF1688 PF07958.6 OAP61797.1 - 2.3e-147 490.8 0.0 2.6e-147 490.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) UPRTase PF14681.1 OAP61798.1 - 3.4e-55 186.4 0.1 1.3e-50 171.5 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAP61798.1 - 5.1e-09 35.9 0.0 7.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Aldedh PF00171.17 OAP61799.1 - 3.2e-127 424.6 0.7 4e-127 424.3 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP61799.1 - 8e-06 24.8 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Cellulase PF00150.13 OAP61799.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Pribosyltran_N PF13793.1 OAP61800.1 - 1.2e-41 141.0 0.1 1.3e-40 137.7 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAP61800.1 - 3.1e-31 108.5 2.4 1.4e-28 99.8 0.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAP61800.1 - 4.1e-07 29.7 2.8 1.2e-06 28.2 1.9 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAP61800.1 - 0.0053 15.9 0.7 0.0089 15.2 0.2 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Mito_morph_reg PF14972.1 OAP61800.1 - 0.065 12.6 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator UPRTase PF14681.1 OAP61801.1 - 5.6e-64 215.1 0.0 6.6e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAP61801.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Transp_cyt_pur PF02133.10 OAP61802.1 - 1.3e-127 426.0 37.4 1.5e-127 425.7 25.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MOSC PF03473.12 OAP61803.1 - 3.9e-21 74.9 0.0 8.2e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 OAP61803.1 - 8.2e-14 51.1 0.3 1.8e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 OAP61803.1 - 3.8e-08 33.8 0.0 3.7e-07 30.6 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 OAP61803.1 - 0.0011 18.9 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Fer2_4 PF13510.1 OAP61803.1 - 0.0059 16.3 0.4 0.023 14.4 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.9 OAP61803.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 3-alpha domain DIOX_N PF14226.1 OAP61804.1 - 1.9e-34 118.6 0.0 2.9e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP61804.1 - 3.4e-22 78.5 0.0 5.9e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ADH_zinc_N PF00107.21 OAP61806.1 - 2.5e-13 49.6 0.0 5.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP61806.1 - 0.0018 19.1 0.0 0.0045 17.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP61806.1 - 0.0054 16.3 0.1 0.0093 15.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Tautomerase_3 PF14832.1 OAP61808.1 - 2.1e-08 34.2 0.0 2.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme YTH PF04146.10 OAP61809.1 - 1.5e-52 176.9 0.0 2.2e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 OAP61809.1 - 1.3e-06 28.3 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP61809.1 - 3.5e-06 26.5 0.0 6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP61809.1 - 0.0037 17.0 0.3 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.13 OAP61810.1 - 1.4e-33 115.0 1.6 3.1e-33 114.0 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 OAP61810.1 - 8.1e-14 51.6 0.1 2.1e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 PH domain RRM_1 PF00076.17 OAP61811.1 - 2.4e-08 33.4 0.0 6.6e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP61811.1 - 8.8e-06 25.4 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP61811.1 - 0.00044 20.1 0.0 0.00092 19.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Autophagy_act_C PF03987.10 OAP61812.1 - 1.9e-12 47.1 0.0 3.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain GST_N_2 PF13409.1 OAP61812.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF336 PF03928.9 OAP61813.1 - 9.1e-20 70.7 0.1 1.2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Plug_translocon PF10559.4 OAP61814.1 - 0.13 11.7 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Plug domain of Sec61p Rotamase PF00639.16 OAP61815.1 - 4.5e-24 85.0 0.0 7e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 OAP61815.1 - 3.7e-16 59.4 0.1 4.6e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 OAP61815.1 - 1.5e-09 37.5 2.5 3e-09 36.5 1.7 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 OAP61815.1 - 1.9e-06 28.4 0.0 3.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Ribosomal_L14 PF00238.14 OAP61816.1 - 3.1e-45 152.8 1.5 3.4e-45 152.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 OAP61817.1 - 2.5e-10 40.9 0.4 1.5e-07 31.9 0.0 3.4 3 0 0 3 3 3 2 SET domain Pyocin_S PF06958.7 OAP61817.1 - 0.027 14.8 0.2 0.027 14.8 0.1 2.4 2 1 0 2 2 2 0 S-type Pyocin adh_short_C2 PF13561.1 OAP61818.1 - 2.5e-15 56.9 0.0 5.5e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP61818.1 - 2.4e-13 50.3 0.0 4.9e-13 49.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61818.1 - 5e-05 23.0 0.0 8.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain MRP-L46 PF11788.3 OAP61819.1 - 8.3e-28 97.2 0.2 2.5e-27 95.7 0.0 1.9 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Exo_endo_phos PF03372.18 OAP61820.1 - 6.4e-07 29.5 1.5 1.2e-06 28.6 1.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.7 OAP61821.1 - 1e-72 244.5 0.5 1.6e-72 243.8 0.4 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.19 OAP61822.1 - 1.7e-11 44.1 0.0 2.5e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 BLVR PF06375.6 OAP61822.1 - 0.0034 17.2 3.2 0.0081 15.9 2.2 1.6 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Sigma70_ner PF04546.8 OAP61822.1 - 0.47 10.0 9.1 19 4.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 OAP61822.1 - 7.1 7.0 10.4 16 5.8 7.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD PF00628.24 OAP61823.1 - 6.4e-18 64.1 14.3 8.9e-12 44.5 5.7 2.4 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 OAP61823.1 - 0.0027 17.4 13.4 0.0053 16.4 1.6 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 OAP61823.1 - 0.0037 16.5 5.0 0.0078 15.5 1.0 2.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 OAP61823.1 - 0.089 12.5 9.0 1.3 8.7 1.9 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 OAP61823.1 - 0.12 11.7 12.0 0.026 13.8 3.0 3.1 3 0 0 3 3 3 0 PHD-finger CENP-B_dimeris PF09026.5 OAP61823.1 - 0.5 10.6 8.5 21 5.4 5.2 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain APP_amyloid PF10515.4 OAP61823.1 - 3.7 7.8 4.5 9.8 6.5 0.0 3.0 3 0 0 3 3 3 0 beta-amyloid precursor protein C-terminus Ras PF00071.17 OAP61824.1 - 1.2e-52 177.6 0.0 1.4e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP61824.1 - 8.6e-16 58.5 0.0 1.5e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP61824.1 - 1.5e-06 27.5 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_6 PF14259.1 OAP61825.1 - 6.2e-38 128.6 0.0 1.3e-09 37.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP61825.1 - 3.3e-36 122.7 0.0 4.1e-11 42.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP61825.1 - 3e-17 62.1 0.0 0.00099 18.9 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 OAP61825.1 - 1.6e-13 50.0 6.0 7.9e-13 47.7 4.2 2.3 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 OAP61825.1 - 2.3e-05 24.1 0.0 0.016 15.0 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 OAP61825.1 - 0.045 13.7 0.0 1.3 9.0 0.0 3.2 4 0 0 4 4 4 0 RNA binding domain DUF4523 PF15023.1 OAP61825.1 - 0.1 12.1 0.0 8.2 5.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) tRNA-synt_2 PF00152.15 OAP61826.1 - 1.1e-70 238.0 0.0 2e-70 237.2 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAP61826.1 - 4e-09 36.1 0.0 7.7e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 OAP61826.1 - 0.085 12.7 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Lectin_leg-like PF03388.8 OAP61827.1 - 1.3e-27 96.4 0.2 2.8e-27 95.3 0.0 1.5 2 0 0 2 2 2 1 Legume-like lectin family IncA PF04156.9 OAP61827.1 - 0.03 13.9 1.6 0.042 13.4 1.1 1.2 1 0 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 OAP61827.1 - 0.059 13.1 1.6 0.24 11.1 1.0 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 OAP61827.1 - 0.099 12.4 0.5 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit TBPIP PF07106.8 OAP61827.1 - 0.16 11.5 0.7 0.33 10.4 0.5 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Alg6_Alg8 PF03155.10 OAP61828.1 - 3.6e-144 481.1 28.2 4.5e-144 480.7 19.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 OAP61829.1 - 8.6e-39 131.8 0.1 2.4e-38 130.4 0.0 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 OAP61829.1 - 7.3e-17 60.8 4.8 1.2e-16 60.1 3.4 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 OAP61829.1 - 2.8e-11 42.8 0.2 6.6e-11 41.6 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 OAP61829.1 - 0.00016 21.3 0.1 0.00048 19.8 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 OAP61829.1 - 0.0036 17.1 0.3 0.021 14.7 0.0 2.4 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Dynamin_N PF00350.18 OAP61829.1 - 0.26 11.1 1.1 0.72 9.6 0.8 1.7 1 0 0 1 1 1 0 Dynamin family Arginase PF00491.16 OAP61830.1 - 6.5e-88 294.6 0.0 7.6e-88 294.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 OAP61830.1 - 0.058 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain ketoacyl-synt PF00109.21 OAP61831.1 - 2.3e-57 194.3 1.4 1.3e-56 191.8 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 OAP61831.1 - 8.2e-33 112.7 1.2 1.6e-32 111.8 0.8 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 OAP61831.1 - 2e-06 27.0 0.2 1.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAP61831.1 - 0.0086 15.5 2.9 0.15 11.5 0.1 3.1 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 OAP61831.1 - 0.014 15.0 2.6 2.8 7.6 0.1 3.4 2 1 1 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SCA7 PF08313.7 OAP61832.1 - 3.2e-34 116.3 1.6 1.2e-33 114.4 1.1 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.9 OAP61832.1 - 0.0061 14.6 10.0 0.0082 14.2 6.9 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF3505 PF12013.3 OAP61832.1 - 0.027 14.6 0.4 0.068 13.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) SAPS PF04499.10 OAP61832.1 - 0.71 8.4 3.0 0.79 8.2 2.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TLP-20 PF06088.6 OAP61832.1 - 1.2 8.7 8.0 2.3 7.8 5.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) mRNA_cap_enzyme PF01331.14 OAP61833.1 - 2.8e-51 173.9 1.7 4.1e-51 173.4 1.2 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 OAP61833.1 - 2.6e-21 75.9 0.3 7e-21 74.5 0.2 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 OAP61833.1 - 2.8e-09 36.6 0.2 1.1e-07 31.4 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain GrpB PF04229.9 OAP61833.1 - 0.012 15.2 3.0 0.012 15.2 2.1 2.0 2 0 0 2 2 2 0 GrpB protein Fungal_trans PF04082.13 OAP61834.1 - 5.1e-18 64.8 1.0 1.1e-17 63.8 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61834.1 - 1.4e-07 31.2 7.6 2.7e-07 30.3 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 OAP61835.1 - 8.9e-13 48.4 0.3 1.6e-12 47.6 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP61835.1 - 0.00011 21.9 0.1 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 KR domain HEAT PF02985.17 OAP61836.1 - 0.029 14.4 7.5 0.56 10.4 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 OAP61836.1 - 7.6 7.1 18.2 14 6.3 0.2 7.5 9 0 0 9 9 9 0 HEAT-like repeat CFEM PF05730.6 OAP61838.1 - 6.9e-10 38.6 4.2 1.7e-09 37.3 2.9 1.7 1 0 0 1 1 1 1 CFEM domain Rifin_STEVOR PF02009.11 OAP61838.1 - 4.3 6.8 5.0 6.2 6.3 3.5 1.3 1 0 0 1 1 1 0 Rifin/stevor family BSD PF03909.12 OAP61839.1 - 8.1e-14 51.1 2.6 3.7e-13 49.0 1.1 2.5 2 0 0 2 2 2 1 BSD domain Suf PF05843.9 OAP61839.1 - 0.091 12.4 2.5 0.08 12.6 0.5 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DNA_ligase_A_M PF01068.16 OAP61841.1 - 9.5e-57 191.6 0.6 6.4e-46 156.2 0.2 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAP61841.1 - 2.5e-52 177.2 0.3 4.1e-52 176.5 0.2 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 OAP61841.1 - 1.4e-28 99.1 0.1 3.2e-27 94.7 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Adeno_E1B_55K_N PF04623.7 OAP61841.1 - 0.065 13.7 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus Ank_2 PF12796.2 OAP61842.1 - 5.5e-74 244.5 9.4 7.2e-11 42.2 0.0 11.0 3 2 8 11 11 11 10 Ankyrin repeats (3 copies) Ank PF00023.25 OAP61842.1 - 5.7e-55 180.4 16.6 0.00029 20.4 0.0 17.4 16 1 1 17 17 17 11 Ankyrin repeat Ank_4 PF13637.1 OAP61842.1 - 3.2e-47 158.1 14.1 1.1e-07 32.1 0.0 10.9 10 1 2 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP61842.1 - 3.1e-40 132.1 11.7 0.031 14.4 0.0 16.9 17 0 0 17 17 17 10 Ankyrin repeat Ank_5 PF13857.1 OAP61842.1 - 6.1e-31 105.7 22.4 0.00081 19.5 0.0 11.9 9 3 3 12 12 12 9 Ankyrin repeats (many copies) ZZ PF00569.12 OAP61842.1 - 0.027 13.9 9.0 0.058 12.9 6.3 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Peptidase_S8 PF00082.17 OAP61844.1 - 2.8e-18 66.0 0.0 4.5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 OAP61844.1 - 6.8e-09 35.9 0.1 0.004 17.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 OAP61844.1 - 2e-08 33.6 0.1 0.012 15.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 OAP61844.1 - 8.7e-06 26.1 0.0 0.29 11.7 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 OAP61844.1 - 1.6e-05 24.4 0.0 0.05 13.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 OAP61844.1 - 0.032 14.4 0.1 7 7.0 0.0 3.9 3 1 0 3 3 3 0 Ankyrin repeats (many copies) RQC PF09382.5 OAP61846.1 - 1.8e-22 79.0 0.1 5.2e-22 77.5 0.0 1.8 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.26 OAP61846.1 - 3.1e-22 78.2 0.1 9.3e-18 63.8 0.0 3.5 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 OAP61846.1 - 5.6e-22 78.0 0.0 1.7e-21 76.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAP61846.1 - 0.00026 20.8 0.0 0.00075 19.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.18 OAP61846.1 - 0.0019 17.8 0.0 0.0067 16.1 0.0 1.9 1 0 0 1 1 1 1 HRDC domain DUF4254 PF14063.1 OAP61846.1 - 0.044 13.3 2.7 0.26 10.8 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) Kelch_3 PF13415.1 OAP61847.1 - 7.3e-31 105.6 12.0 1.1e-09 38.2 0.0 7.9 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.1 OAP61847.1 - 1.1e-30 105.0 16.1 8.2e-09 35.1 0.0 6.8 6 2 0 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 OAP61847.1 - 5.3e-27 93.5 2.4 5.3e-27 93.5 1.7 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 OAP61847.1 - 5e-19 67.5 4.9 7.4e-06 25.9 0.0 5.9 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 OAP61847.1 - 8.6e-19 67.0 6.8 3.9e-06 26.7 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 OAP61847.1 - 2.7e-15 55.6 7.5 2.6e-10 39.6 0.1 5.9 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 OAP61847.1 - 1.2e-13 50.1 14.8 9.2e-05 22.0 0.0 6.3 6 1 0 6 6 6 4 Kelch motif Gpi16 PF04113.9 OAP61848.1 - 4e-227 754.7 0.0 4.5e-227 754.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Coagulin PF02035.10 OAP61848.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Coagulin LUC7 PF03194.10 OAP61849.1 - 2.9e-68 230.1 0.5 3.6e-68 229.8 0.3 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 OAP61849.1 - 0.036 13.6 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FliJ PF02050.11 OAP61849.1 - 0.76 9.8 4.5 0.18 11.8 0.2 2.1 3 0 0 3 3 3 0 Flagellar FliJ protein GRP PF07172.6 OAP61849.1 - 1.6 9.2 39.0 3.2 8.2 27.0 1.5 1 0 0 1 1 1 0 Glycine rich protein family Pkinase PF00069.20 OAP61850.1 - 6.3e-68 228.7 0.2 6.2e-67 225.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61850.1 - 5.8e-44 150.0 0.0 9.1e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP61850.1 - 7.2e-11 41.5 0.0 1.6e-08 33.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 OAP61850.1 - 0.0014 18.4 4.3 0.66 9.6 0.2 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 OAP61850.1 - 0.021 13.8 0.0 0.067 12.2 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.24 OAP61851.1 - 3.3e-41 140.5 0.0 4.3e-40 136.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP61851.1 - 6.7e-26 89.9 0.1 1.6e-25 88.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2984 PF11203.3 OAP61851.1 - 0.08 13.0 2.8 0.16 12.0 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) DUF2986 PF11661.3 OAP61851.1 - 0.21 11.9 9.2 0.025 14.9 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Spc7_N PF15402.1 OAP61852.1 - 2.8e-261 869.5 66.4 2.8e-261 869.5 46.0 2.2 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 OAP61852.1 - 2.7e-83 279.3 6.0 4.5e-83 278.6 4.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 OAP61852.1 - 0.034 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Spc7_C2 Ribosomal_S17 PF00366.15 OAP61853.1 - 1.1e-29 102.2 0.5 1.7e-29 101.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Oxidored_FMN PF00724.15 OAP61854.1 - 2.2e-51 174.8 0.0 3.5e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.13 OAP61854.1 - 0.036 12.9 0.1 0.1 11.3 0.0 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase WD40 PF00400.27 OAP61855.1 - 7.3e-09 35.1 0.6 0.04 13.8 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Glyco_hydro_2 PF00703.16 OAP61857.1 - 8.6e-12 45.4 0.0 2.2e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 OAP61857.1 - 2.7e-08 33.5 0.0 5.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Fungal_trans PF04082.13 OAP61858.1 - 4.6e-17 61.7 0.1 1.1e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61858.1 - 4.6e-08 32.8 15.1 7.2e-08 32.2 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_2 PF00328.17 OAP61859.1 - 1.1e-54 186.1 0.0 1.5e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GMC_oxred_N PF00732.14 OAP61859.1 - 2.9e-46 157.9 0.0 4.8e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP61859.1 - 1.4e-40 138.8 0.1 2.8e-40 137.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAP61859.1 - 0.013 15.4 0.1 0.044 13.8 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 OAP61860.1 - 2.5e-26 92.2 48.7 2.5e-26 92.2 33.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FGGY_C PF02782.11 OAP61861.1 - 2.7e-72 242.5 1.3 4.3e-72 241.8 0.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 OAP61861.1 - 3.7e-69 232.7 0.0 4.9e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 OAP61861.1 - 0.0083 15.4 0.3 0.98 8.6 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family MIP PF00230.15 OAP61862.1 - 5.2e-56 189.6 6.3 6.7e-56 189.2 4.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans PF04082.13 OAP61864.1 - 1.5e-07 30.5 0.3 2.8e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61864.1 - 3.7e-05 23.5 8.6 3.7e-05 23.5 6.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP61865.1 - 3.5e-43 147.6 49.4 3.5e-43 147.6 34.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP61865.1 - 3.5e-11 42.0 17.1 8.9e-11 40.6 11.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ILVD_EDD PF00920.16 OAP61866.1 - 6.9e-204 678.0 1.6 8e-204 677.8 1.1 1.0 1 0 0 1 1 1 1 Dehydratase family Cyclase PF04199.8 OAP61867.1 - 3.2e-15 56.2 0.1 5.4e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 Putative cyclase Vps54 PF07928.7 OAP61868.1 - 1.3e-48 164.5 0.1 3.9e-48 162.9 0.1 1.9 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 OAP61868.1 - 2e-05 23.6 1.8 2e-05 23.6 1.3 2.6 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 OAP61868.1 - 0.00016 21.3 0.8 0.00038 20.0 0.5 1.6 1 0 0 1 1 1 1 LUC7 N_terminus PAD PF03068.10 OAP61868.1 - 0.023 13.1 0.0 0.047 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) HET PF06985.6 OAP61870.1 - 6.5e-11 42.5 0.8 4.3e-07 30.1 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 OAP61871.1 - 2.8e-36 124.9 30.9 2.8e-36 124.9 21.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MCM PF00493.18 OAP61872.1 - 3.5e-142 473.0 0.6 4.7e-142 472.6 0.4 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAP61872.1 - 8.8e-20 71.4 0.2 2.1e-19 70.1 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAP61872.1 - 1.2e-06 27.8 0.0 0.00023 20.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAP61872.1 - 2.5e-05 24.0 0.0 5.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAP61872.1 - 0.00046 19.8 0.2 0.0019 17.7 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAP61872.1 - 0.021 14.2 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 OAP61872.1 - 0.083 13.0 0.2 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Velvet PF11754.3 OAP61873.1 - 3.4e-05 23.5 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Pkinase PF00069.20 OAP61874.1 - 9.5e-48 162.5 0.0 1.9e-47 161.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61874.1 - 2.4e-24 85.7 0.0 4.3e-24 84.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP61874.1 - 0.047 12.6 0.1 0.21 10.5 0.0 1.9 1 1 0 1 1 1 0 Kinase-like PhyH PF05721.8 OAP61875.1 - 1.1e-24 87.6 0.3 1.6e-24 87.1 0.2 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ADH_zinc_N PF00107.21 OAP61876.1 - 6.4e-22 77.5 0.2 1.2e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP61876.1 - 1.9e-21 75.8 1.5 3.2e-21 75.1 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 OAP61876.1 - 6.2e-05 22.6 1.0 0.0001 21.8 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 OAP61876.1 - 0.12 11.5 0.3 0.22 10.6 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DLH PF01738.13 OAP61878.1 - 2.2e-24 85.9 0.0 2.6e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP61878.1 - 2.6e-08 33.7 0.0 3.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 OAP61878.1 - 0.0025 17.3 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 OAP61878.1 - 0.011 15.5 0.0 0.89 9.3 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP61878.1 - 0.053 12.7 0.0 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 OAP61878.1 - 0.081 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Acyl-CoA_dh_1 PF00441.19 OAP61879.1 - 7.4e-36 123.5 1.0 1.9e-35 122.1 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 OAP61879.1 - 4.5e-13 49.6 0.0 7.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP61879.1 - 5.3e-12 45.0 0.2 1.1e-11 44.0 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAP61879.1 - 3.8e-09 37.1 0.0 1.6e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 OAP61879.1 - 0.0031 16.9 0.1 0.014 14.8 0.1 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Metallophos PF00149.23 OAP61882.1 - 3.6e-11 42.8 3.1 7e-11 41.9 2.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase p450 PF00067.17 OAP61883.1 - 4.6e-49 167.1 0.0 8.2e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 OAP61883.1 - 3.3e-08 32.8 0.0 1.3e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II DUF4077 PF13295.1 OAP61883.1 - 0.21 11.2 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4077) Methyltransf_23 PF13489.1 OAP61884.1 - 1.1e-17 64.2 0.0 1.7e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61884.1 - 3e-07 30.9 0.0 1.3e-05 25.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP61884.1 - 6.4e-07 29.7 0.0 1.4e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP61884.1 - 2.1e-06 28.0 0.0 1.7e-05 25.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP61884.1 - 2.1e-05 24.1 0.0 0.00027 20.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAP61884.1 - 0.005 16.8 0.0 0.0068 16.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 OAP61884.1 - 0.021 13.8 0.0 0.042 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 OAP61884.1 - 0.025 13.6 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) EspA PF03433.8 OAP61884.1 - 0.038 13.4 0.1 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 EspA-like secreted protein Methyltransf_25 PF13649.1 OAP61884.1 - 0.045 14.1 0.0 0.19 12.1 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 OAP61884.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 OAP61884.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain LCCL PF03815.14 OAP61885.1 - 1.3e-20 73.1 0.0 2.2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 LCCL domain AMP-binding PF00501.23 OAP61886.1 - 1e-80 271.2 0.0 1.2e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cys_Met_Meta_PP PF01053.15 OAP61887.1 - 1.8e-147 490.6 0.0 2.1e-147 490.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 OAP61887.1 - 3.5e-10 39.4 0.2 7.1e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 OAP61887.1 - 6.5e-10 38.4 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAP61887.1 - 2.1e-05 23.4 0.1 3.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 OAP61887.1 - 5.5e-05 22.4 0.0 0.0001 21.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 OAP61887.1 - 0.0013 17.3 0.0 0.0018 16.8 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Met_gamma_lyase PF06838.6 OAP61887.1 - 0.022 13.0 0.0 0.03 12.6 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase MFS_1 PF07690.11 OAP61888.1 - 1.8e-50 171.6 31.8 5.4e-37 127.3 10.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP61888.1 - 3.8e-08 32.1 27.8 2.8e-05 22.6 5.4 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 OAP61888.1 - 0.056 11.4 1.0 0.39 8.7 0.5 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MARVEL PF01284.18 OAP61889.1 - 9.5e-20 70.8 17.0 1.1e-19 70.6 11.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain Herpes_UL45 PF05473.7 OAP61889.1 - 0.12 11.8 0.7 0.21 10.9 0.5 1.4 1 0 0 1 1 1 0 UL45 protein DUF3169 PF11368.3 OAP61889.1 - 0.42 9.7 2.6 0.78 8.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF1440 PF07274.7 OAP61889.1 - 0.58 10.1 4.8 0.17 11.8 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) TRP PF06011.7 OAP61889.1 - 1.5 7.2 9.4 1.2 7.5 0.0 2.6 1 1 0 2 2 2 0 Transient receptor potential (TRP) ion channel Fungal_trans_2 PF11951.3 OAP61890.1 - 8.1e-09 34.5 0.6 1.2e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain EF-hand_4 PF12763.2 OAP61891.1 - 1.6e-33 114.5 0.0 7.5e-13 48.1 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 OAP61891.1 - 8.3e-10 38.6 0.0 1.6e-05 24.9 0.0 4.1 4 1 1 5 5 4 1 EF-hand domain pair EF-hand_1 PF00036.27 OAP61891.1 - 1.3e-08 33.5 0.4 0.22 10.9 0.0 5.5 5 0 0 5 5 5 1 EF hand UBA PF00627.26 OAP61891.1 - 6e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 OAP61891.1 - 0.00063 19.4 1.5 18 5.5 0.1 5.2 5 0 0 5 5 5 0 EF-hand domain IncA PF04156.9 OAP61891.1 - 0.0015 18.1 12.7 0.0015 18.1 8.8 2.5 2 1 1 3 3 2 2 IncA protein Reo_sigmaC PF04582.7 OAP61891.1 - 0.0093 15.1 12.9 0.045 12.9 3.1 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein MitMem_reg PF13012.1 OAP61891.1 - 0.02 14.9 13.3 0.12 12.4 3.3 2.8 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function AAA_27 PF13514.1 OAP61891.1 - 0.065 10.9 31.5 0.1 10.2 21.8 1.1 1 0 0 1 1 1 0 AAA domain EF-hand_8 PF13833.1 OAP61891.1 - 0.072 12.7 0.0 5.2 6.7 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair GOLGA2L5 PF15070.1 OAP61891.1 - 0.08 11.4 24.8 0.13 10.7 17.2 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF3584 PF12128.3 OAP61891.1 - 0.18 9.1 33.2 0.26 8.5 23.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF960 PF06124.6 OAP61891.1 - 0.27 11.5 0.0 1.4e+02 2.8 0.0 3.2 3 0 0 3 3 3 0 Staphylococcal protein of unknown function (DUF960) Macoilin PF09726.4 OAP61891.1 - 0.32 9.2 28.8 0.0096 14.2 15.2 1.7 2 0 0 2 2 2 0 Transmembrane protein MbeD_MobD PF04899.7 OAP61891.1 - 0.38 10.6 20.2 0.21 11.5 2.7 4.0 3 1 2 5 5 3 0 MbeD/MobD like Filament PF00038.16 OAP61891.1 - 0.92 8.9 33.7 0.041 13.3 12.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein Atg14 PF10186.4 OAP61891.1 - 0.98 8.3 35.7 0.17 10.7 19.6 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 OAP61891.1 - 1 8.7 38.5 4.2 6.7 26.2 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.6 OAP61891.1 - 1 7.9 34.3 1.5 7.3 4.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 OAP61891.1 - 1.1 7.6 25.6 2 6.7 17.7 1.4 1 0 0 1 1 1 0 AAA domain Myosin_tail_1 PF01576.14 OAP61891.1 - 1.1 6.8 42.1 3 5.4 29.2 1.5 1 1 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.4 OAP61891.1 - 1.2 8.9 41.5 0.053 13.3 15.0 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 OAP61891.1 - 1.7 8.4 19.9 0.075 12.8 3.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.6 OAP61891.1 - 2.1 6.5 25.6 3.7 5.7 17.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MAD PF05557.8 OAP61891.1 - 2.9 5.8 31.4 5.2 5.0 21.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein YlqD PF11068.3 OAP61891.1 - 3.7 7.6 34.7 5 7.1 11.1 2.3 2 0 0 2 2 2 0 YlqD protein GAS PF13851.1 OAP61891.1 - 3.8 6.6 37.2 2.2 7.3 15.1 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 OAP61891.1 - 5.8 5.2 42.1 38 2.5 29.2 1.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light BicD PF09730.4 OAP61891.1 - 6.1 5.0 33.4 67 1.6 22.6 2.0 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D ATG16 PF08614.6 OAP61891.1 - 8 6.2 38.0 0.33 10.7 16.2 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 OAP61891.1 - 9.7 6.3 25.9 1 9.4 6.1 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tubulin PF00091.20 OAP61892.1 - 8.9e-70 234.8 0.0 1.3e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAP61892.1 - 7.8e-50 168.1 0.1 1.4e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 OAP61892.1 - 0.0015 18.0 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 OAP61892.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Dioxygenase_C PF00775.16 OAP61894.1 - 4.9e-49 166.0 0.0 7.5e-49 165.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 OAP61894.1 - 2.5e-12 46.5 0.1 6.1e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Fungal_trans PF04082.13 OAP61894.1 - 9.5e-10 37.7 0.1 1.8e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP61894.1 - 2.8e-05 23.9 16.0 4.8e-05 23.1 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CarboxypepD_reg PF13620.1 OAP61894.1 - 0.003 17.5 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Nol1_Nop2_Fmu PF01189.12 OAP61895.1 - 5.3e-97 324.5 0.0 8.5e-97 323.9 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 OAP61895.1 - 0.00096 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 OAP61895.1 - 0.021 15.3 0.3 0.17 12.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Zn_clus PF00172.13 OAP61896.1 - 2.7e-08 33.5 9.3 7e-08 32.2 6.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRG PF05712.8 OAP61896.1 - 0.078 11.8 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 MRG Glycogen_syn PF05693.8 OAP61897.1 - 0 1114.5 0.0 0 1114.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 OAP61897.1 - 4.4e-06 26.2 0.0 0.0094 15.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAP61897.1 - 2.4e-05 24.5 0.1 4.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Sulfatase PF00884.18 OAP61898.1 - 2.6e-63 214.0 1.3 3.3e-63 213.7 0.9 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 OAP61898.1 - 1.7e-06 27.6 0.6 2.8e-06 26.9 0.4 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 OAP61898.1 - 0.098 11.0 0.1 0.32 9.3 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF229) polyprenyl_synt PF00348.12 OAP61899.1 - 1.8e-71 240.0 0.0 2.1e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase XPA_C PF05181.7 OAP61900.1 - 1.7e-28 97.9 3.1 3.6e-28 96.9 2.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 OAP61900.1 - 7.1e-06 25.6 2.6 7.1e-06 25.6 1.8 1.8 2 0 0 2 2 2 1 XPA protein N-terminal YhfH PF14149.1 OAP61900.1 - 0.1 12.4 1.8 0.64 9.8 0.1 2.7 2 0 0 2 2 2 0 YhfH-like protein Striatin PF08232.7 OAP61901.1 - 3.4e-38 131.0 8.6 3.4e-38 131.0 6.0 2.0 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 OAP61901.1 - 2.6e-16 58.8 6.2 1.9e-05 24.3 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat DivIVA PF05103.8 OAP61901.1 - 6.4 6.8 10.8 0.25 11.3 2.1 2.1 2 0 0 2 2 2 0 DivIVA protein 4HBT PF03061.17 OAP61904.1 - 2.4e-07 30.7 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Sugar_tr PF00083.19 OAP61905.1 - 1.6e-60 204.9 15.2 6.6e-58 196.3 10.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61905.1 - 6.3e-15 54.7 31.1 6.3e-15 54.7 21.5 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MerE PF05052.7 OAP61905.1 - 0.019 14.9 0.4 0.063 13.2 0.3 1.9 1 0 0 1 1 1 0 MerE protein Catalase PF00199.14 OAP61906.1 - 1e-12 47.4 0.0 2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Catalase DUF3405 PF11885.3 OAP61907.1 - 7.1e-131 436.8 0.6 8.5e-131 436.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Dynamin_N PF00350.18 OAP61908.1 - 5e-28 98.0 0.5 1.2e-27 96.7 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 OAP61908.1 - 2.9e-15 55.8 0.1 1.6e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 OAP61908.1 - 0.0011 18.8 0.0 0.0057 16.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 OAP61908.1 - 0.0022 18.0 0.0 0.0069 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain TINF2_N PF14973.1 OAP61908.1 - 0.0034 17.5 1.2 0.031 14.4 0.1 2.8 3 0 0 3 3 3 1 TERF1-interacting nuclear factor 2 N-terminus Miro PF08477.8 OAP61908.1 - 0.0036 17.7 0.0 0.025 15.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 OAP61908.1 - 0.058 13.6 0.1 0.45 10.8 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 OAP61908.1 - 0.067 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AA_permease_2 PF13520.1 OAP61909.1 - 2.9e-94 316.0 36.0 3.6e-94 315.6 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP61909.1 - 9e-20 70.4 29.9 1.2e-19 70.0 20.7 1.2 1 0 0 1 1 1 1 Amino acid permease Vma12 PF11712.3 OAP61909.1 - 0.23 11.1 4.2 1.2 8.8 0.1 2.8 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Alpha-amylase PF00128.19 OAP61910.1 - 5.4e-19 68.7 0.0 1.1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain FtsX PF02687.16 OAP61911.1 - 0.042 13.5 1.7 0.07 12.8 1.2 1.3 1 0 0 1 1 1 0 FtsX-like permease family Zn_clus PF00172.13 OAP61912.1 - 1.8e-08 34.1 7.7 2.8e-08 33.5 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP61912.1 - 5.6e-06 25.2 0.0 8.7e-06 24.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hpre_diP_synt_I PF07456.6 OAP61913.1 - 1 9.1 8.8 4.3 7.1 3.8 2.4 2 1 0 2 2 2 0 Heptaprenyl diphosphate synthase component I DUF427 PF04248.7 OAP61914.1 - 1.4e-27 95.1 0.3 1.6e-27 95.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DEAD PF00270.24 OAP61915.1 - 1.8e-39 134.9 0.8 3.2e-39 134.1 0.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP61915.1 - 7.8e-23 80.1 0.0 7.3e-12 44.9 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 OAP61915.1 - 2.9e-07 30.5 0.6 6.8e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YoaP PF14268.1 OAP61915.1 - 0.094 11.9 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 YoaP-like GMC_oxred_N PF00732.14 OAP61916.1 - 1.4e-65 221.3 0.0 1.9e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase SIR2 PF02146.12 OAP61916.1 - 3.7e-56 189.6 0.0 5.7e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family GMC_oxred_C PF05199.8 OAP61916.1 - 5.1e-19 69.0 0.0 1.3e-18 67.6 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 OAP61916.1 - 0.00058 18.8 0.1 0.00087 18.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein SF-assemblin PF06705.6 OAP61916.1 - 0.046 12.8 0.7 0.071 12.2 0.5 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin UPF0184 PF03670.8 OAP61916.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Phage_NinH PF06322.6 OAP61916.1 - 0.19 11.3 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Phage NinH protein Hexokinase_2 PF03727.11 OAP61918.1 - 3.3e-89 298.2 0.0 4.5e-89 297.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 OAP61918.1 - 2.5e-77 258.8 0.0 1.8e-76 256.0 0.0 1.9 2 0 0 2 2 2 1 Hexokinase WD40 PF00400.27 OAP61919.1 - 1e-06 28.3 0.0 0.03 14.2 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat COG4 PF08318.7 OAP61921.1 - 2e-102 342.3 0.0 3.4e-102 341.6 0.0 1.4 1 0 0 1 1 1 1 COG4 transport protein Sec6 PF06046.8 OAP61921.1 - 0.0079 14.3 0.0 0.098 10.7 0.0 2.2 1 1 0 1 1 1 1 Exocyst complex component Sec6 MitMem_reg PF13012.1 OAP61921.1 - 0.019 15.0 0.6 10 6.2 0.0 3.3 4 0 0 4 4 4 0 Maintenance of mitochondrial structure and function RINT1_TIP1 PF04437.8 OAP61921.1 - 0.075 11.5 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 RINT-1 / TIP-1 family HAUS-augmin3 PF14932.1 OAP61921.1 - 0.12 11.5 4.8 0.22 10.6 3.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Nsp1_C PF05064.8 OAP61921.1 - 0.19 11.4 2.9 1 9.0 0.3 2.8 1 1 1 2 2 2 0 Nsp1-like C-terminal region HSCB_C PF07743.8 OAP61921.1 - 0.68 10.4 7.2 29 5.2 0.4 4.1 4 0 0 4 4 4 0 HSCB C-terminal oligomerisation domain WD40 PF00400.27 OAP61922.1 - 4.7e-61 200.6 27.5 2.8e-12 45.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAP61922.1 - 2.1e-05 22.8 5.9 0.16 10.1 0.1 3.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 OAP61922.1 - 0.001 18.8 0.1 0.14 11.8 0.0 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAP61922.1 - 0.0092 14.3 0.0 0.56 8.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Aldo_ket_red PF00248.16 OAP61923.1 - 3.2e-70 236.1 0.0 3.7e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sdh5 PF03937.11 OAP61924.1 - 1.4e-22 79.1 0.2 3.1e-22 78.0 0.1 1.6 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase MFS_1 PF07690.11 OAP61925.1 - 1.9e-38 132.1 42.2 2.3e-38 131.7 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP61925.1 - 1.5e-09 36.6 2.6 2.5e-09 35.9 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAS PF00989.19 OAP61926.1 - 0.0036 17.0 0.0 0.077 12.7 0.0 2.3 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 OAP61926.1 - 0.0047 16.8 9.3 0.0047 16.8 6.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF874 PF05917.6 OAP61926.1 - 0.016 14.1 0.3 0.031 13.1 0.2 1.4 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Flavokinase PF01687.12 OAP61927.1 - 9.8e-35 119.1 0.0 1.2e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Mito_fiss_reg PF05308.6 OAP61927.1 - 0.056 12.8 5.9 0.079 12.3 4.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator E1-E2_ATPase PF00122.15 OAP61928.1 - 6.4e-78 260.9 0.6 1.4e-77 259.8 0.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAP61928.1 - 1.5e-45 154.9 1.0 1.5e-45 154.9 0.7 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAP61928.1 - 1.2e-30 107.5 0.0 2.8e-29 103.0 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAP61928.1 - 8.1e-21 73.2 0.4 1.7e-20 72.2 0.3 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 OAP61928.1 - 4.7e-15 56.2 0.0 4.7e-14 52.9 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP61928.1 - 8.6e-11 41.6 0.0 1.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAP61928.1 - 5.6e-07 29.3 0.8 1.5e-05 24.7 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 OAP61929.1 - 4.1e-37 126.5 0.0 7.1e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 OAP61929.1 - 1.2e-07 30.8 0.0 2.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3176 PF11374.3 OAP61930.1 - 4.8e-26 90.8 0.2 4.8e-26 90.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Acyltransferase PF01553.16 OAP61931.1 - 1.4e-12 47.2 0.0 5.7e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.4 OAP61932.1 - 1.2e-46 157.0 1.8 1.3e-46 156.8 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Val_tRNA-synt_C PF10458.4 OAP61932.1 - 0.058 13.4 0.4 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF2161 PF09929.4 OAP61932.1 - 0.074 12.9 0.2 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Cas_APE2256 PF09651.5 OAP61932.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) DUF1556 PF07590.6 OAP61933.1 - 5.3 7.3 8.0 0.99 9.6 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) DUF159 PF02586.9 OAP61934.1 - 2.5e-56 190.4 0.5 6.5e-56 189.1 0.4 1.7 1 1 0 1 1 1 1 Uncharacterised ACR, COG2135 Vfa1 PF08432.5 OAP61934.1 - 6 6.8 21.5 0.21 11.6 2.7 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 OAP61934.1 - 7.5 6.9 6.9 6.4 7.1 1.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_2 PF07719.12 OAP61935.1 - 0.0057 16.4 0.8 1.8 8.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP61935.1 - 0.0067 16.1 2.8 3.7 7.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP61935.1 - 0.014 15.9 7.1 5.5 7.9 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 OAP61935.1 - 0.021 14.2 0.0 2.5 7.4 0.0 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_12 PF13424.1 OAP61935.1 - 0.023 14.6 2.4 1.3 8.9 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 OAP61935.1 - 0.057 13.3 4.1 1.7 8.6 1.8 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP61935.1 - 0.12 12.2 0.1 4.9 7.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3433 PF11915.3 OAP61936.1 - 4.6e-40 135.6 13.8 3.7e-21 75.0 0.5 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Glyco_hydro_cc PF11790.3 OAP61937.1 - 6.6e-60 202.5 0.2 8.4e-60 202.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RED_N PF07808.8 OAP61938.1 - 2.5e-10 39.9 7.2 2.5e-10 39.9 5.0 2.1 2 1 1 3 3 3 1 RED-like protein N-terminal region Methyltransf_15 PF09445.5 OAP61939.1 - 1.1e-49 168.1 0.0 1.5e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 OAP61939.1 - 1.1e-09 38.3 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 OAP61939.1 - 8.9e-09 35.1 0.1 3.3e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 OAP61939.1 - 2.2e-08 34.6 0.0 3.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAP61939.1 - 2.9e-07 30.2 0.0 3.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 OAP61939.1 - 0.00013 21.3 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 OAP61939.1 - 0.00015 21.3 0.1 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 OAP61939.1 - 0.0029 17.0 0.0 0.007 15.7 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.8 OAP61939.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.6 OAP61939.1 - 0.12 10.9 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_11 PF08241.7 OAP61939.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.14 OAP61939.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family DUF3591 PF12157.3 OAP61940.1 - 2.5e-177 589.9 4.6 4e-177 589.1 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) OrfB_Zn_ribbon PF07282.6 OAP61940.1 - 0.016 14.8 1.8 0.032 13.8 1.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-CCHC PF00098.18 OAP61940.1 - 0.025 14.4 0.9 0.025 14.4 0.6 2.1 2 0 0 2 2 2 0 Zinc knuckle DUF2310 PF10071.4 OAP61940.1 - 0.046 12.6 0.1 0.081 11.8 0.1 1.3 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Elf1 PF05129.8 OAP61940.1 - 0.072 12.7 0.3 0.19 11.4 0.2 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ADK_lid PF05191.9 OAP61940.1 - 0.44 10.2 3.6 1.2 8.8 2.5 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-CCHC_6 PF15288.1 OAP61940.1 - 3.3 7.4 8.8 0.14 11.8 1.1 2.2 2 0 0 2 2 2 0 Zinc knuckle DAO PF01266.19 OAP61941.1 - 5.1e-50 170.3 0.1 6.6e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP61941.1 - 1.2e-07 31.6 0.2 0.01 15.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP61941.1 - 1.3e-06 28.4 0.1 0.00034 20.5 0.1 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP61941.1 - 1.3e-05 25.3 0.2 0.00091 19.3 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP61941.1 - 2.2e-05 23.2 0.0 0.0014 17.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 OAP61941.1 - 2.7e-05 23.1 0.0 0.00011 21.1 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 OAP61941.1 - 0.00026 20.0 0.0 0.086 11.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP61941.1 - 0.00096 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 OAP61941.1 - 0.0029 16.8 0.0 0.18 10.9 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Shikimate_DH PF01488.15 OAP61941.1 - 0.028 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PALP PF00291.20 OAP61942.1 - 2.8e-10 39.9 0.0 4.8e-10 39.1 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ring_hydroxyl_A PF00848.14 OAP61943.1 - 2.3e-38 131.9 0.2 6.6e-38 130.4 0.2 1.8 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 OAP61943.1 - 2.2e-14 52.7 0.0 4.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.13 OAP61943.1 - 2.1e-06 26.8 0.2 5e-06 25.5 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain PBP_sp32 PF07222.7 OAP61943.1 - 0.31 10.1 1.4 1.5 7.9 0.1 2.5 3 0 0 3 3 3 0 Proacrosin binding protein sp32 DAO PF01266.19 OAP61944.1 - 1.4e-65 221.5 0.1 2.4e-65 220.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 OAP61944.1 - 4.5e-55 186.2 0.1 1.1e-54 185.0 0.0 1.7 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 OAP61944.1 - 1.5e-16 60.1 0.1 3.3e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 OAP61944.1 - 8.9e-06 25.8 0.0 6e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP61944.1 - 3.1e-05 24.2 0.1 0.09 13.1 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 OAP61944.1 - 0.00084 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.1 OAP61944.1 - 0.00085 19.1 0.2 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding SoxG PF04268.7 OAP61944.1 - 0.0014 18.4 0.1 0.038 13.8 0.0 2.6 3 0 0 3 3 3 1 Sarcosine oxidase, gamma subunit family TrkA_N PF02254.13 OAP61944.1 - 0.002 18.0 0.2 0.0082 16.1 0.0 2.1 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.1 OAP61944.1 - 0.0081 16.1 0.0 0.028 14.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAP61944.1 - 0.011 14.8 0.1 1.6 7.7 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 OAP61944.1 - 0.049 13.5 0.0 0.33 10.7 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 OAP61944.1 - 0.098 13.0 0.0 0.58 10.6 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FKBP_C PF00254.23 OAP61945.1 - 1.9e-28 98.3 0.0 5.8e-28 96.7 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase IMS PF00817.15 OAP61946.1 - 1.7e-43 147.9 0.0 3.5e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAP61946.1 - 1.4e-17 63.8 0.0 4.4e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 OAP61946.1 - 2e-09 37.3 26.2 1e-06 28.5 1.0 5.4 5 2 1 6 6 6 3 Domain of unknown function (DUF4414) BRCT PF00533.21 OAP61946.1 - 8.7e-08 32.2 0.0 1.9e-06 27.8 0.0 2.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 OAP61946.1 - 1e-05 25.2 0.4 7.3e-05 22.5 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 OAP61946.1 - 0.00014 21.6 0.1 0.00034 20.4 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain HHH_5 PF14520.1 OAP61946.1 - 0.025 14.7 0.0 0.081 13.1 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF1805 PF08827.6 OAP61946.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Pkinase PF00069.20 OAP61947.1 - 4.2e-33 114.6 1.9 9e-26 90.5 0.1 4.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP61947.1 - 6.9e-14 51.5 0.0 1.6e-12 47.0 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.18 OAP61947.1 - 0.0082 15.8 1.1 0.044 13.5 0.5 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAP61947.1 - 0.07 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Oxidored_FMN PF00724.15 OAP61948.1 - 1.9e-89 300.0 0.0 2.2e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 OAP61951.1 - 2.5e-29 102.0 32.2 3.2e-29 101.7 22.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 OAP61951.1 - 0.03 14.3 0.3 0.03 14.3 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Arf PF00025.16 OAP61952.1 - 1.2e-42 145.0 0.0 1.5e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 OAP61952.1 - 1e-18 67.2 0.0 1.2e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP61952.1 - 7.8e-12 45.7 0.0 1.1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAP61952.1 - 2.3e-08 34.0 0.0 3.7e-08 33.3 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAP61952.1 - 3.4e-08 32.9 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 OAP61952.1 - 1.5e-07 30.8 0.0 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 OAP61952.1 - 9.1e-06 25.2 0.0 0.00034 20.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 OAP61952.1 - 3.1e-05 22.8 0.0 5.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Dynamin_N PF00350.18 OAP61952.1 - 6.2e-05 22.8 0.0 0.019 14.7 0.0 2.2 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.13 OAP61952.1 - 0.00014 21.2 0.4 0.00088 18.5 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.22 OAP61952.1 - 0.023 14.9 0.0 0.027 14.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 OAP61952.1 - 0.03 13.8 0.0 0.29 10.6 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 OAP61952.1 - 0.088 12.5 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RCR PF12273.3 OAP61953.1 - 1.1e-25 90.6 8.9 1.7e-25 90.0 6.2 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF3382 PF11862.3 OAP61953.1 - 0.014 15.2 0.3 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) DUF4131 PF13567.1 OAP61953.1 - 0.021 14.2 0.4 0.025 13.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FtsX PF02687.16 OAP61953.1 - 0.056 13.2 0.9 0.08 12.7 0.6 1.1 1 0 0 1 1 1 0 FtsX-like permease family TF_Otx PF03529.8 OAP61953.1 - 0.18 12.0 3.3 0.28 11.4 2.3 1.2 1 0 0 1 1 1 0 Otx1 transcription factor LSR PF05624.9 OAP61953.1 - 0.5 10.1 1.9 0.75 9.5 1.3 1.3 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Conotoxin PF02950.12 OAP61955.1 - 0.021 15.6 2.4 0.3 11.9 0.0 2.5 2 0 0 2 2 2 0 Conotoxin Proteasome PF00227.21 OAP61957.1 - 9.8e-49 165.2 0.1 1.2e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cupin_5 PF06172.6 OAP61958.1 - 4.6e-25 88.1 0.0 7e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Miro PF08477.8 OAP61959.1 - 8.4e-37 126.3 0.0 4.2e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 OAP61959.1 - 3.3e-34 116.5 0.0 6e-34 115.6 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 OAP61959.1 - 1.3e-30 104.4 0.5 2.7e-30 103.4 0.3 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 OAP61959.1 - 1.9e-25 89.1 0.0 5.6e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 OAP61959.1 - 6.3e-09 35.8 0.0 0.00084 19.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 OAP61959.1 - 2.3e-05 24.4 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 OAP61959.1 - 0.00023 21.3 0.0 0.44 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 OAP61959.1 - 0.0004 20.2 0.1 0.19 11.5 0.0 3.0 2 1 1 3 3 3 1 Dynamin family EF-hand_7 PF13499.1 OAP61959.1 - 0.00049 20.1 1.9 0.067 13.3 0.5 2.7 2 0 0 2 2 2 1 EF-hand domain pair AAA_29 PF13555.1 OAP61959.1 - 0.00075 18.9 0.0 0.29 10.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 OAP61959.1 - 0.0015 18.0 0.0 0.85 9.0 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain EF-hand_1 PF00036.27 OAP61959.1 - 0.0023 17.1 2.2 0.13 11.6 0.3 2.6 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.1 OAP61959.1 - 0.005 16.4 1.5 0.16 11.6 0.1 2.9 3 0 0 3 3 3 1 EF hand RNA_helicase PF00910.17 OAP61959.1 - 0.011 15.9 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 OAP61959.1 - 0.032 14.1 0.0 5 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 OAP61959.1 - 0.044 13.4 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 OAP61959.1 - 0.066 12.9 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 OAP61959.1 - 0.067 12.5 0.0 7.8 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAP61959.1 - 0.077 12.9 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 OAP61959.1 - 0.081 12.3 0.0 3.8 6.9 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_24 PF13479.1 OAP61959.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain EF-hand_6 PF13405.1 OAP61959.1 - 0.14 12.0 4.2 0.45 10.5 0.4 2.7 2 0 0 2 2 2 0 EF-hand domain ABC_tran PF00005.22 OAP61959.1 - 0.15 12.3 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter EF-hand_8 PF13833.1 OAP61959.1 - 0.23 11.1 2.5 8.4 6.0 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain pair DUF500 PF04366.7 OAP61960.1 - 2.5e-44 149.7 0.2 5.1e-44 148.7 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 OAP61960.1 - 1.1e-14 53.4 0.4 3.3e-14 52.0 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 OAP61960.1 - 8.3e-14 50.8 0.2 2.1e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 OAP61960.1 - 1.9e-11 43.3 0.0 3.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 OAP61961.1 - 3.5e-18 65.4 32.1 3.5e-18 65.4 22.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP61961.1 - 3.1e-05 22.7 10.0 3.1e-05 22.7 6.9 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter 7TMR-DISM_7TM PF07695.6 OAP61961.1 - 0.0018 17.9 10.3 0.0018 17.9 7.2 3.5 2 1 1 3 3 3 1 7TM diverse intracellular signalling DUF4149 PF13664.1 OAP61961.1 - 1.3 9.1 9.8 0.16 12.0 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DDHD PF02862.12 OAP61962.1 - 5.2e-70 235.7 3.5 3.4e-69 233.1 0.1 2.4 2 0 0 2 2 2 1 DDHD domain DUF676 PF05057.9 OAP61962.1 - 0.058 12.6 0.2 0.68 9.1 0.0 2.5 3 0 0 3 3 3 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 OAP61962.1 - 0.11 12.2 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family CH PF00307.26 OAP61963.1 - 1.1e-62 208.7 0.0 1.3e-17 63.7 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 OAP61963.1 - 3.3e-09 36.7 1.1 5.5e-08 32.8 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 OAP61963.1 - 1.4e-05 24.0 0.8 0.28 10.5 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 OAP61963.1 - 0.00073 19.2 1.1 0.023 14.5 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain CAMSAP_CH PF11971.3 OAP61963.1 - 0.00078 19.0 0.0 0.29 10.8 0.0 3.9 4 0 0 4 4 4 1 CAMSAP CH domain DLH PF01738.13 OAP61964.1 - 1.1e-28 99.9 0.0 1.4e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP61964.1 - 1.5e-06 28.0 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP61964.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.11 OAP61965.1 - 2e-30 105.6 21.8 3e-30 105.1 15.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.6 OAP61966.1 - 2.6e-33 115.1 0.0 1.2e-27 96.8 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ppx-GppA PF02541.11 OAP61967.1 - 6.3e-42 143.7 0.0 1.9e-31 109.3 0.0 2.1 2 0 0 2 2 2 2 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 OAP61967.1 - 0.02 13.3 0.1 0.037 12.5 0.1 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family SWI-SNF_Ssr4 PF08549.5 OAP61968.1 - 6.9e-156 520.3 29.7 1.6e-88 297.7 3.2 2.4 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) Orbi_VP6 PF01516.11 OAP61968.1 - 0.32 10.0 4.0 0.52 9.3 2.7 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 Sld5 PF05916.6 OAP61969.1 - 7.4e-09 35.8 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Cullin PF00888.17 OAP61970.1 - 8.2e-134 447.3 9.7 1.1e-133 446.9 6.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 OAP61970.1 - 7.2e-29 99.4 0.3 7.2e-29 99.4 0.2 2.8 3 0 0 3 3 3 1 Cullin protein neddylation domain HTH_IclR PF09339.5 OAP61970.1 - 0.0035 16.8 0.0 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain Rrf2 PF02082.15 OAP61970.1 - 0.022 14.8 0.4 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator RHH_3 PF12651.2 OAP61970.1 - 0.029 14.0 0.1 0.19 11.5 0.0 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain zf-DNL PF05180.7 OAP61971.1 - 2.4e-26 91.2 0.4 3.9e-26 90.5 0.3 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 OAP61971.1 - 0.044 13.2 0.3 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_4 PF13717.1 OAP61971.1 - 0.11 12.2 1.3 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 OAP61971.1 - 0.14 11.7 1.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Alpha-amylase PF00128.19 OAP61972.1 - 7.6e-100 334.3 0.2 1.1e-99 333.8 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 OAP61972.1 - 6.7e-06 26.1 0.1 4e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) DUF3533 PF12051.3 OAP61973.1 - 4.8e-80 269.1 3.3 5.5e-80 268.9 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Alpha-L-AF_C PF06964.7 OAP61974.1 - 3.9e-34 117.9 0.3 7.5e-34 117.0 0.2 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus F-box PF00646.28 OAP61975.1 - 0.0012 18.4 0.2 0.0041 16.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP61975.1 - 0.015 14.9 0.1 0.04 13.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like Sugar_tr PF00083.19 OAP61976.1 - 2.4e-73 247.2 24.9 2.7e-73 247.0 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61976.1 - 2.1e-16 59.6 38.4 8.3e-11 41.1 10.2 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP61976.1 - 5.4e-05 21.7 23.9 0.00011 20.7 5.9 2.9 2 2 0 2 2 2 2 MFS/sugar transport protein DUF4243 PF14027.1 OAP61979.1 - 1.1e-71 241.9 4.3 1.3e-71 241.7 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Ldh_2 PF02615.9 OAP61980.1 - 8.1e-100 333.7 0.0 9.2e-100 333.6 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase PHY PF00360.15 OAP61981.1 - 5.7e-27 94.0 0.0 2.7e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.21 OAP61981.1 - 1.3e-17 63.4 0.1 3.7e-17 62.0 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 OAP61981.1 - 4e-16 59.5 0.0 2.2e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 GAF domain Response_reg PF00072.19 OAP61981.1 - 1.2e-12 47.8 0.0 4.8e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 OAP61981.1 - 1.2e-12 47.6 0.3 3.5e-12 46.1 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 OAP61981.1 - 2.6e-09 37.5 0.0 8.6e-09 35.8 0.0 2.0 1 0 0 1 1 1 1 PAS fold DUF1870 PF08965.5 OAP61981.1 - 0.074 12.7 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) Fungal_trans_2 PF11951.3 OAP61982.1 - 0.044 12.3 0.2 0.61 8.6 0.0 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain MARVEL PF01284.18 OAP61983.1 - 0.083 12.7 16.9 0.25 11.1 12.0 1.6 1 1 1 2 2 2 0 Membrane-associating domain UCH_1 PF13423.1 OAP61984.1 - 1.1e-64 218.7 0.2 1.5e-64 218.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 OAP61984.1 - 2.6e-18 66.8 0.0 4.5e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 OAP61984.1 - 5.4e-05 22.4 0.0 0.00051 19.2 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Serglycin PF04360.7 OAP61984.1 - 1.1 9.0 5.9 1.7 8.3 3.4 1.9 2 0 0 2 2 2 0 Serglycin zf-RING_2 PF13639.1 OAP61985.1 - 2.6e-09 36.7 2.3 3.6e-09 36.2 1.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAP61985.1 - 1.2e-05 25.3 0.9 3e-05 24.0 0.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAP61985.1 - 0.0014 18.4 0.1 0.002 17.9 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 OAP61985.1 - 0.011 15.8 2.2 0.018 15.0 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 OAP61985.1 - 0.02 14.8 0.1 0.051 13.5 0.1 1.7 1 0 0 1 1 1 0 zinc-finger zf-C3HC4 PF00097.20 OAP61985.1 - 0.14 11.8 1.2 0.25 11.0 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_zinc_N PF00107.21 OAP61986.1 - 6.4e-25 87.2 0.0 1.5e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP61986.1 - 1.1e-05 26.3 0.0 3.7e-05 24.6 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.15 OAP61986.1 - 0.064 13.1 0.5 0.14 12.0 0.3 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sulfatase PF00884.18 OAP61987.1 - 4.7e-76 255.9 0.0 5.9e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 OAP61987.1 - 0.002 18.4 0.1 0.074 13.3 0.0 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 OAP61987.1 - 0.019 14.2 0.0 0.054 12.8 0.0 1.8 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sugar_tr PF00083.19 OAP61988.1 - 3e-106 355.7 29.0 3.6e-106 355.4 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP61988.1 - 2.2e-18 66.0 30.8 2.2e-18 66.0 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_MCEL PF03291.11 OAP61989.1 - 6.5e-60 202.7 0.0 1.4e-57 195.0 0.0 3.1 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 OAP61989.1 - 5.8e-09 36.3 0.0 2.3e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61989.1 - 1.3e-08 35.3 0.0 2.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP61989.1 - 1.1e-07 32.2 0.0 0.025 15.0 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 OAP61989.1 - 2.3e-07 30.6 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP61989.1 - 1.1e-06 28.3 0.0 0.00013 21.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP61989.1 - 5.7e-06 26.6 0.0 1.4e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 OAP61989.1 - 0.013 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family C1_1 PF00130.17 OAP61990.1 - 0.00079 19.1 1.9 0.0015 18.1 1.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 OAP61990.1 - 0.0016 18.2 4.5 0.0036 17.0 3.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAP61990.1 - 0.0041 17.1 2.4 0.0098 15.9 1.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 OAP61990.1 - 0.089 12.7 4.3 0.21 11.5 3.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 OAP61990.1 - 0.12 12.3 2.6 0.34 10.9 1.8 1.7 1 0 0 1 1 1 0 RING-like domain C1_4 PF07975.7 OAP61990.1 - 0.22 11.5 3.4 0.53 10.3 2.4 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain Apt1 PF10351.4 OAP61990.1 - 1.6 7.5 4.3 2.1 7.0 3.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PHD PF00628.24 OAP61990.1 - 7.4 6.3 8.8 1.3 8.8 3.1 1.9 2 0 0 2 2 2 0 PHD-finger GRASP55_65 PF04495.9 OAP61992.1 - 9.8e-41 138.9 0.0 7.5e-40 136.1 0.0 1.9 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain HD PF01966.17 OAP61993.1 - 8.3e-05 22.5 0.3 0.00048 20.1 0.1 2.2 2 1 0 2 2 2 1 HD domain Methyltransf_2 PF00891.13 OAP61994.1 - 1.1e-36 126.2 0.0 1.6e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 OAP61994.1 - 0.006 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP61994.1 - 0.007 16.8 0.0 0.024 15.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP61994.1 - 0.015 15.8 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HTH_19 PF12844.2 OAP61994.1 - 0.039 14.0 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain bZIP_1 PF00170.16 OAP61995.1 - 1.1e-06 28.5 12.0 1.7e-06 27.9 8.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 OAP61995.1 - 0.00023 21.4 6.9 0.00043 20.5 4.8 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 OAP61995.1 - 0.00066 19.4 12.7 0.001 18.8 8.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper HALZ PF02183.13 OAP61995.1 - 0.0058 16.3 0.3 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper DNA_methylase PF00145.12 OAP61995.1 - 0.041 12.9 0.3 0.048 12.7 0.2 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase CDC45 PF02724.9 OAP61995.1 - 0.06 11.3 4.9 0.074 11.0 3.4 1.0 1 0 0 1 1 1 0 CDC45-like protein EURL PF06937.6 OAP61995.1 - 0.17 11.2 3.9 0.21 10.9 2.7 1.1 1 0 0 1 1 1 0 EURL protein Presenilin PF01080.12 OAP61995.1 - 0.27 10.0 2.7 0.36 9.6 1.9 1.1 1 0 0 1 1 1 0 Presenilin IncA PF04156.9 OAP61995.1 - 0.59 9.6 3.2 0.8 9.2 2.2 1.2 1 0 0 1 1 1 0 IncA protein Bap31 PF05529.7 OAP61995.1 - 2.3 7.6 4.2 3.1 7.2 2.9 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Mnd1 PF03962.10 OAP61995.1 - 3.6 7.2 8.5 4.3 6.9 5.9 1.3 1 1 0 1 1 1 0 Mnd1 family p450 PF00067.17 OAP61996.1 - 6e-76 255.8 0.0 7.7e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AP_endonuc_2 PF01261.19 OAP61997.1 - 3.4e-28 98.3 0.1 5.1e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel YL1 PF05764.8 OAP61998.1 - 4e-43 147.7 34.5 4e-43 147.7 23.9 3.0 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 OAP61998.1 - 5.5e-06 25.8 0.0 9.4e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ecl1 PF12855.2 OAP61999.1 - 2.7e-14 52.1 4.0 4.2e-14 51.5 2.8 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 OAP61999.1 - 0.0011 18.8 4.4 0.0024 17.6 3.1 1.5 1 0 0 1 1 1 1 MYND finger DUF581 PF04570.9 OAP61999.1 - 0.0064 15.7 5.6 0.014 14.6 3.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF581) DUF2256 PF10013.4 OAP61999.1 - 1.8 8.3 4.9 7.3 6.4 3.4 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) E1-E2_ATPase PF00122.15 OAP62000.1 - 2.3e-18 66.0 0.1 4.3e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAP62000.1 - 3.6e-18 66.4 0.1 1.4e-17 64.5 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP62000.1 - 6.4e-13 49.6 1.3 1e-11 45.6 0.9 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP62000.1 - 2.7e-11 43.2 0.0 8.9e-11 41.6 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAP62000.1 - 0.002 17.7 0.4 0.02 14.4 0.1 2.3 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAP62000.1 - 0.023 14.8 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 OAP62001.1 - 1.1e-23 84.0 0.0 1.7e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAP62001.1 - 6.4e-08 32.4 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF348 PF03990.9 OAP62001.1 - 0.059 12.9 0.4 0.19 11.3 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF348) Cwf_Cwc_15 PF04889.7 OAP62002.1 - 1.2e-65 221.5 18.6 1.2e-65 221.5 12.9 2.4 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF1212 PF06738.7 OAP62002.1 - 1e-42 145.7 10.4 5.2e-39 133.7 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 OAP62002.1 - 2.5e-26 92.1 12.2 2.5e-26 92.1 8.5 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3815) GDE_N PF12439.3 OAP62002.1 - 0.023 13.9 0.1 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal DHFR_1 PF00186.14 OAP62004.1 - 1.8e-19 69.8 0.0 4.9e-09 35.9 0.0 4.3 4 0 0 4 4 4 4 Dihydrofolate reductase Med22 PF06179.7 OAP62005.1 - 5.4e-12 45.6 0.2 1.4e-11 44.3 0.2 1.7 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex ATG13 PF10033.4 OAP62007.1 - 5.3e-68 228.9 0.0 1.2e-67 227.7 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 13 RCC1 PF00415.13 OAP62008.1 - 6.2e-22 77.5 0.1 1.2e-06 28.6 0.0 5.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 OAP62008.1 - 4.4e-16 58.8 0.2 7.4e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 OAP62008.1 - 1e-09 38.6 0.5 2.3e-08 34.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 OAP62008.1 - 4.2e-09 35.7 5.2 1.4e-07 30.9 0.7 3.8 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 OAP62008.1 - 8.9e-08 31.6 0.1 0.026 14.7 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 OAP62008.1 - 3.9e-06 27.1 0.0 1.4e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAP62008.1 - 0.00031 20.4 0.1 0.09 12.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 OAP62008.1 - 0.01 16.0 0.1 0.31 11.3 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Asp PF00026.18 OAP62009.1 - 1.1e-63 215.4 5.3 1.5e-63 214.9 3.7 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAP62009.1 - 6.3e-09 35.9 0.3 2.5e-08 34.0 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAP62009.1 - 0.0065 16.0 0.3 0.21 11.1 0.1 2.6 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal BUD22 PF09073.5 OAP62011.1 - 1.2e-73 248.6 7.3 1.4e-73 248.4 5.1 1.1 1 0 0 1 1 1 1 BUD22 YebO PF13974.1 OAP62011.1 - 0.14 11.9 2.2 0.25 11.1 0.7 2.1 2 0 0 2 2 2 0 YebO-like protein Abhydrolase_3 PF07859.8 OAP62012.1 - 2.2e-40 138.4 0.1 1.3e-30 106.5 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold ParA PF10609.4 OAP62012.1 - 1.6e-33 114.3 0.6 3.7e-33 113.2 0.4 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like DUF2424 PF10340.4 OAP62012.1 - 3e-14 52.4 0.0 8e-14 51.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) CbiA PF01656.18 OAP62012.1 - 8e-14 51.4 0.0 1.6e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAP62012.1 - 1.1e-06 28.6 0.0 5.7e-06 26.3 0.0 2.1 3 0 0 3 3 3 1 AAA domain COesterase PF00135.23 OAP62012.1 - 0.00089 18.0 0.1 0.079 11.6 0.0 2.2 2 0 0 2 2 2 1 Carboxylesterase family ArsA_ATPase PF02374.10 OAP62012.1 - 0.001 18.2 1.4 0.0071 15.4 0.2 2.3 3 0 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 OAP62012.1 - 0.0022 17.1 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Abhydrolase_5 PF12695.2 OAP62012.1 - 0.0026 17.5 0.0 0.0082 15.8 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_25 PF13481.1 OAP62012.1 - 0.0058 16.0 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Asp PF00026.18 OAP62013.1 - 1.2e-41 143.0 0.2 1.9e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.1 OAP62013.1 - 3.8e-05 23.4 0.1 9.8e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAP62013.1 - 0.00032 21.1 1.1 0.0062 17.0 0.2 3.2 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 OAP62013.1 - 0.024 14.2 0.0 0.15 11.5 0.0 2.2 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal RVP PF00077.15 OAP62013.1 - 0.076 12.9 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Zn_clus PF00172.13 OAP62014.1 - 2.6e-07 30.4 7.8 4.2e-07 29.7 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 OAP62015.1 - 7.9e-28 96.6 0.0 1.4e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 OAP62015.1 - 3.6e-25 88.7 0.0 5.4e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain LisH PF08513.6 OAP62015.1 - 0.14 11.9 1.9 0.24 11.2 0.1 2.3 3 0 0 3 3 3 0 LisH Sugar_tr PF00083.19 OAP62016.1 - 7e-73 245.7 34.7 8.1e-73 245.5 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62016.1 - 9.3e-30 103.5 44.1 4.1e-25 88.2 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 OAP62017.1 - 5e-22 78.5 2.1 1.3e-21 77.2 1.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP62017.1 - 9e-19 68.1 0.9 7.9e-18 65.1 0.6 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP62017.1 - 9.8e-09 35.1 0.4 1.8e-08 34.2 0.3 1.5 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 OAP62017.1 - 0.0018 17.3 0.2 0.0026 16.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 OAP62017.1 - 0.0039 16.6 0.3 0.0057 16.1 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP62017.1 - 0.0064 15.4 0.0 0.0096 14.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.16 OAP62017.1 - 0.023 14.5 1.4 0.068 12.9 0.4 2.0 2 0 0 2 2 2 0 ThiF family Eno-Rase_NADH_b PF12242.3 OAP62017.1 - 0.058 13.1 1.6 0.19 11.5 1.1 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase VCBS PF13517.1 OAP62017.1 - 0.072 13.4 0.1 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 3HCDH_N PF02737.13 OAP62017.1 - 0.092 12.3 0.2 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAP62017.1 - 1.7 8.7 4.1 3.6 7.6 1.3 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 OAP62018.1 - 2.4e-23 83.2 0.0 7.7e-22 78.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP62018.1 - 9.7e-14 50.4 0.1 6.6e-13 47.7 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP62018.1 - 9.2e-12 44.8 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP62018.1 - 4.8e-08 32.2 0.0 8.2e-07 28.2 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP62018.1 - 5.7e-07 29.6 0.0 0.00038 20.3 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP62018.1 - 0.00066 18.6 0.0 0.95 8.2 0.0 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 OAP62018.1 - 0.0018 18.0 0.0 0.62 9.8 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 OAP62018.1 - 0.0055 15.6 0.0 0.34 9.7 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP62018.1 - 0.0091 15.1 0.0 0.41 9.7 0.0 2.5 2 0 0 2 2 2 1 Thi4 family Malic_M PF03949.10 OAP62018.1 - 0.073 12.6 0.0 21 4.5 0.0 2.9 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain p450 PF00067.17 OAP62019.1 - 2.1e-55 188.1 0.0 1.4e-54 185.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 OAP62020.1 - 5.7e-16 58.8 0.0 1.2e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP62020.1 - 6.5e-07 29.3 0.1 1.7e-06 27.9 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 OAP62020.1 - 2.9e-05 23.0 0.4 4.9e-05 22.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.5 OAP62020.1 - 0.02 14.5 0.4 0.47 10.0 0.2 2.6 2 1 0 2 2 2 0 KR domain LBR_tudor PF09465.5 OAP62020.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Pyr_redox_3 PF13738.1 OAP62021.1 - 1.3e-22 80.9 0.0 2.3e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP62021.1 - 1.7e-11 43.9 0.0 5e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 OAP62021.1 - 1.6e-10 39.8 0.0 6.1e-10 37.9 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP62021.1 - 0.00018 20.5 0.0 0.0032 16.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 OAP62021.1 - 0.002 17.2 0.0 0.13 11.3 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 OAP62021.1 - 0.011 15.5 0.0 0.25 11.0 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 OAP62021.1 - 0.1 11.0 0.0 0.18 10.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF4188 PF13826.1 OAP62021.1 - 0.33 11.0 3.4 3.3 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4188) adh_short PF00106.20 OAP62022.1 - 1.7e-23 83.3 0.4 4.1e-23 82.1 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62022.1 - 2.4e-09 37.1 0.6 5.8e-08 32.6 0.4 2.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP62022.1 - 3.3e-09 36.8 0.0 5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAP62022.1 - 0.0041 16.8 0.0 0.0041 16.8 0.0 3.0 5 0 0 5 5 5 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 OAP62022.1 - 0.0054 16.3 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 OAP62022.1 - 0.0077 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP62022.1 - 0.062 13.3 0.1 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Abhydrolase_3 PF07859.8 OAP62023.1 - 6.5e-50 169.6 0.6 9.5e-50 169.0 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP62023.1 - 4e-05 22.5 0.7 8.9e-05 21.3 0.5 1.5 1 1 0 1 1 1 1 Carboxylesterase family p450 PF00067.17 OAP62024.1 - 1.4e-55 188.6 0.0 2.2e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 OAP62024.1 - 5.7e-29 100.7 2.8 9.7e-29 100.0 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S15 PF02129.13 OAP62025.1 - 2.4e-33 115.7 5.1 1.4e-30 106.6 0.6 3.0 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 OAP62025.1 - 3.1e-25 89.3 0.0 4.1e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain adh_short_C2 PF13561.1 OAP62026.1 - 2.1e-31 109.5 0.0 2.5e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP62026.1 - 5.7e-28 97.9 0.0 8.1e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62026.1 - 2.1e-06 27.5 0.0 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 OAP62026.1 - 0.022 13.8 0.1 2.5 7.2 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 OAP62026.1 - 0.048 13.5 0.1 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 OAP62026.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Acyl-CoA_dh_1 PF00441.19 OAP62027.1 - 9.4e-33 113.4 0.4 1.5e-32 112.7 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP62027.1 - 1.5e-20 72.4 1.0 2.9e-20 71.5 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAP62027.1 - 1.8e-16 60.7 0.0 4.7e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Pox_T4_N PF04491.7 OAP62027.1 - 0.047 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus Abhydrolase_6 PF12697.2 OAP62028.1 - 5.2e-32 111.5 0.2 6e-32 111.3 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62028.1 - 1.7e-16 60.5 0.0 1.9e-11 43.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP62028.1 - 3.4e-08 33.3 0.0 6.7e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP62028.1 - 0.0046 16.7 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Aa_trans PF01490.13 OAP62029.1 - 2.5e-26 92.1 37.8 4.2e-26 91.3 26.2 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Catalase PF00199.14 OAP62030.1 - 7.5e-115 383.6 0.0 9.3e-115 383.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAP62030.1 - 8.7e-10 38.3 0.0 1.7e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 OAP62030.1 - 0.039 13.4 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family MFS_1 PF07690.11 OAP62033.1 - 2.2e-39 135.1 26.7 2.2e-39 135.1 18.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TPP_enzyme_N PF02776.13 OAP62034.1 - 1.4e-37 128.7 0.3 6.5e-35 120.1 0.1 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAP62034.1 - 8.2e-19 67.6 0.1 2e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP62034.1 - 9.9e-19 67.4 0.0 2.2e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TauD PF02668.11 OAP62035.1 - 1.9e-49 168.6 1.0 2.2e-49 168.4 0.7 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lactamase_B PF00753.22 OAP62036.1 - 1.5e-10 41.1 0.3 2.1e-10 40.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP62036.1 - 0.00034 20.2 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.19 OAP62037.1 - 1.2e-80 271.2 28.2 1.4e-80 271.0 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62037.1 - 8.3e-31 106.9 48.0 2.2e-28 99.0 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily B_lectin PF01453.19 OAP62037.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 D-mannose binding lectin SnoaL_4 PF13577.1 OAP62038.1 - 3.4e-12 46.3 5.1 4.3e-12 46.0 3.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF2605 PF10792.4 OAP62038.1 - 0.021 14.5 0.1 0.03 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) SnoaL_2 PF12680.2 OAP62038.1 - 0.034 14.5 2.7 0.071 13.5 1.6 2.0 1 1 0 1 1 1 0 SnoaL-like domain AHSA1 PF08327.6 OAP62038.1 - 0.29 11.2 2.0 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein Oxidored_FMN PF00724.15 OAP62039.1 - 1.2e-63 215.2 0.0 1.6e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GST_N_3 PF13417.1 OAP62040.1 - 1.7e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP62040.1 - 2e-07 30.9 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP62040.1 - 1.5e-06 28.2 0.0 3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain EthD PF07110.6 OAP62041.1 - 1.2e-21 77.4 0.1 1.5e-21 77.1 0.1 1.1 1 0 0 1 1 1 1 EthD domain adh_short PF00106.20 OAP62042.1 - 3.3e-27 95.4 0.1 4.7e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62042.1 - 5e-13 49.0 0.1 7.3e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP62042.1 - 1.1e-08 34.3 0.1 1.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 OAP62042.1 - 2.1e-07 30.9 0.0 3.2e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP62042.1 - 1.2e-06 28.1 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 OAP62042.1 - 0.00019 21.2 0.5 0.00056 19.7 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 OAP62042.1 - 0.00032 19.4 0.1 0.00046 18.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ThiF PF00899.16 OAP62042.1 - 0.048 13.4 0.9 0.1 12.4 0.6 1.5 1 0 0 1 1 1 0 ThiF family RmlD_sub_bind PF04321.12 OAP62042.1 - 0.058 12.2 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 OAP62042.1 - 0.059 13.3 0.4 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF261 PF03196.8 OAP62042.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF261 ABM PF03992.11 OAP62043.1 - 0.0012 18.8 0.4 0.0012 18.8 0.3 1.5 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Caveolin PF01146.12 OAP62043.1 - 0.057 13.0 0.1 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Caveolin ORC6 PF05460.8 OAP62043.1 - 0.1 11.6 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) EHN PF06441.7 OAP62044.1 - 2.8e-38 130.2 0.3 7e-37 125.7 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAP62044.1 - 1.3e-09 38.2 0.3 3.2e-09 37.0 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62044.1 - 5.6e-06 26.0 0.2 1.4e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Aldo_ket_red PF00248.16 OAP62045.1 - 1.6e-47 161.7 0.0 1.8e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.14 OAP62046.1 - 4.5e-76 256.2 0.0 6.5e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 OAP62046.1 - 2.5e-14 53.5 0.0 4.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP62046.1 - 8.2e-05 22.4 0.1 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP62046.1 - 9.7e-05 21.9 0.0 0.0004 19.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 OAP62046.1 - 0.00026 20.7 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 OAP62046.1 - 0.046 13.7 0.1 0.087 12.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 OAP62047.1 - 9.7e-14 51.6 0.0 1.8e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP62047.1 - 1.4e-09 38.0 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP62047.1 - 1.5e-05 24.5 0.6 0.00018 21.0 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 OAP62047.1 - 0.0027 17.3 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain MT PF12777.2 OAP62047.1 - 0.059 12.0 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor NAD_binding_4 PF07993.7 OAP62047.1 - 0.066 12.1 0.4 4.2 6.2 0.0 2.5 2 1 0 2 2 2 0 Male sterility protein Pro_CA PF00484.14 OAP62048.1 - 2.4e-20 73.0 0.0 3.2e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase ARID PF01388.16 OAP62050.1 - 9e-19 67.1 0.1 3e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Rhodanese PF00581.15 OAP62052.1 - 1.3e-11 44.8 0.0 3e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain PNP_UDP_1 PF01048.15 OAP62053.1 - 8.4e-09 34.7 0.3 1.1e-08 34.4 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2694 PF10904.3 OAP62053.1 - 0.078 12.9 0.1 0.095 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) An_peroxidase PF03098.10 OAP62053.1 - 0.11 10.8 0.0 0.11 10.8 0.0 1.0 1 0 0 1 1 1 0 Animal haem peroxidase DUF2011 PF09428.5 OAP62054.1 - 1.8e-26 92.5 6.7 2.8e-26 91.9 4.7 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) ELFV_dehydrog PF00208.16 OAP62055.1 - 1.8e-60 204.5 0.0 4.6e-60 203.2 0.0 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 OAP62055.1 - 4.1e-19 67.6 0.2 2.8e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 OAP62055.1 - 0.0024 17.4 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF3661 PF12400.3 OAP62056.1 - 1.8e-42 144.5 0.6 2.6e-42 143.9 0.4 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein ABC2_membrane_3 PF12698.2 OAP62056.1 - 0.0087 15.1 0.9 0.0087 15.1 0.7 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF4126 PF13548.1 OAP62056.1 - 0.05 13.0 0.6 0.19 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) DUF946 PF06101.6 OAP62057.1 - 1.6e-12 46.2 0.8 1.6e-12 46.2 0.5 1.5 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) DUF1302 PF06980.6 OAP62057.1 - 0.06 11.9 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) AIRC PF00731.15 OAP62059.1 - 1.1e-56 190.2 2.3 2.1e-56 189.3 1.6 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 OAP62059.1 - 2.9e-51 173.2 0.0 4.5e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 OAP62059.1 - 6.6e-11 42.2 0.0 6.8e-10 38.9 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAP62059.1 - 0.002 17.5 0.0 0.0047 16.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 OAP62059.1 - 0.016 13.9 0.0 0.87 8.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon XdhC_C PF13478.1 OAP62059.1 - 0.033 14.4 0.3 0.32 11.3 0.0 2.6 3 0 0 3 3 3 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 OAP62059.1 - 0.1 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.17 OAP62060.1 - 1.3e-17 63.1 0.1 1.9e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP62060.1 - 5e-12 45.6 0.0 7.3e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP62060.1 - 9.6e-12 44.5 0.1 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JmjC PF02373.17 OAP62061.1 - 1.3e-09 38.2 0.1 6.6e-09 36.0 0.1 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 OAP62061.1 - 2.8e-09 36.5 7.4 2.8e-09 36.5 5.1 2.3 3 0 0 3 3 3 1 PHD-finger Cupin_8 PF13621.1 OAP62061.1 - 8.8e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain DUF1423 PF07227.6 OAP62061.1 - 0.0025 16.5 0.7 0.0052 15.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1423) PHD_2 PF13831.1 OAP62061.1 - 0.011 15.0 3.6 0.031 13.5 2.5 1.8 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 OAP62061.1 - 1.5 8.5 9.6 0.054 13.2 1.7 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_clus PF00172.13 OAP62061.1 - 4.5 7.2 32.6 0.05 13.5 2.4 4.2 3 1 1 4 4 4 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 OAP62062.1 - 1.9e-48 162.0 0.2 3.5e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF788 PF05620.6 OAP62063.1 - 2.6e-44 151.0 0.0 2.9e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) TPR_1 PF00515.23 OAP62064.1 - 3.8e-38 127.5 14.8 1.2e-07 31.0 0.1 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 OAP62064.1 - 2e-36 123.4 27.3 2.4e-11 43.0 3.8 7.7 4 1 4 8 8 8 7 TPR repeat TPR_2 PF07719.12 OAP62064.1 - 4.5e-34 113.6 20.6 9.7e-07 28.2 0.1 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat Apc3 PF12895.2 OAP62064.1 - 9e-26 89.8 19.8 6.8e-16 58.1 0.1 5.4 2 1 5 7 7 7 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 OAP62064.1 - 4e-24 84.6 14.8 7.6e-10 39.2 1.6 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAP62064.1 - 2.7e-19 69.2 11.8 0.0001 22.5 0.4 6.6 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAP62064.1 - 3.3e-19 67.1 4.6 0.00052 19.5 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAP62064.1 - 4.8e-19 67.1 17.5 0.0028 18.1 0.0 9.6 5 1 5 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 OAP62064.1 - 6.7e-19 67.6 14.9 1.9e-05 24.4 0.0 7.0 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 OAP62064.1 - 1.7e-18 65.1 9.9 0.01 15.9 0.2 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAP62064.1 - 3.5e-11 42.0 10.3 0.083 12.7 0.0 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 OAP62064.1 - 2.4e-09 37.0 10.1 0.19 12.2 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 OAP62064.1 - 1.3e-07 31.3 11.6 0.0052 16.6 0.1 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat FAT PF02259.18 OAP62064.1 - 0.0019 17.2 3.7 0.0046 15.9 0.3 2.5 2 1 0 2 2 2 1 FAT domain TPR_10 PF13374.1 OAP62064.1 - 0.034 14.0 6.8 13 5.8 0.0 6.1 6 1 1 7 7 6 0 Tetratricopeptide repeat MIT PF04212.13 OAP62064.1 - 0.039 13.8 1.0 6 6.8 0.9 3.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 OAP62064.1 - 0.045 12.5 0.2 3.6 6.2 0.0 3.2 2 2 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) RINGv PF12906.2 OAP62066.1 - 7.6e-16 57.8 8.3 1.3e-15 57.1 5.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 OAP62066.1 - 0.11 12.3 7.2 0.21 11.4 5.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 OAP62066.1 - 0.2 11.4 4.4 0.18 11.6 1.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF823 PF05689.6 OAP62066.1 - 0.23 10.7 0.1 0.45 9.8 0.1 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) AvrPtoB-E3_ubiq PF09046.5 OAP62066.1 - 0.39 10.7 0.3 12 5.9 0.1 2.3 2 0 0 2 2 2 0 AvrPtoB E3 ubiquitin ligase ECH_C PF13766.1 OAP62067.1 - 0.24 11.5 3.8 1 9.5 0.4 2.3 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region DUF1932 PF09130.6 OAP62068.1 - 3.7e-16 58.6 0.0 1.1e-15 57.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 OAP62068.1 - 0.00012 22.4 0.0 0.00047 20.5 0.0 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 OAP62068.1 - 0.002 18.0 0.0 0.016 15.0 0.1 2.4 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 OAP62068.1 - 0.0083 15.8 0.0 0.094 12.4 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 OAP62068.1 - 0.1 11.7 0.3 1.5 7.9 0.0 2.2 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3451 PF11933.3 OAP62068.1 - 1.1 8.9 5.2 0.34 10.6 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3451) ILVD_EDD PF00920.16 OAP62069.1 - 4.9e-154 513.6 0.3 6e-154 513.3 0.2 1.1 1 0 0 1 1 1 1 Dehydratase family Glyoxalase PF00903.20 OAP62070.1 - 2.1e-40 137.6 0.0 4.9e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP62070.1 - 1e-29 103.3 0.0 2.2e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 OAP62070.1 - 6.8e-17 61.4 0.0 5.9e-07 29.4 0.0 3.8 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 OAP62070.1 - 1.8e-06 28.0 0.0 0.051 13.4 0.0 3.2 2 1 0 2 2 2 2 Glyoxalase-like domain MoaF PF10703.4 OAP62070.1 - 0.0016 17.5 0.0 0.078 12.0 0.0 2.1 2 0 0 2 2 2 1 Molybdenum cofactor biosynthesis protein F DUF4105 PF13387.1 OAP62070.1 - 0.0033 16.6 0.0 9.8 5.3 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4105) Fe-ADH PF00465.14 OAP62071.1 - 1.7e-101 339.4 0.0 2.2e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAP62071.1 - 4.3e-16 58.9 0.0 1.4e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 OAP62071.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein 2-Hacid_dh_C PF02826.14 OAP62072.1 - 1.6e-54 183.7 0.0 2.4e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP62072.1 - 4.2e-35 120.0 0.1 8.2e-35 119.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 OAP62072.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 OAP62072.1 - 0.023 14.5 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 OAP62072.1 - 0.029 14.6 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_2 PF03446.10 OAP62072.1 - 0.039 13.7 0.3 0.09 12.6 0.2 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 OAP62072.1 - 0.077 12.5 0.0 0.45 10.0 0.0 2.5 1 1 0 1 1 1 0 ACT domain Glyco_hydro_43 PF04616.9 OAP62073.1 - 1.6e-67 227.6 0.0 2e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Complex1_30kDa PF00329.14 OAP62074.1 - 9e-37 125.4 0.1 1.3e-36 124.9 0.1 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 OAP62075.1 - 2e-17 62.4 13.3 3.6e-17 61.6 9.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 OAP62075.1 - 1.4e-06 27.8 7.2 2.6e-06 27.0 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 OAP62075.1 - 4.3e-05 23.0 0.0 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 OAP62075.1 - 6e-05 22.7 10.0 0.00012 21.7 7.0 1.6 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 OAP62075.1 - 0.00022 20.4 4.5 0.00022 20.4 3.1 2.7 3 0 0 3 3 3 1 Rtf2 RING-finger RRM_5 PF13893.1 OAP62075.1 - 0.00025 20.8 0.0 0.00061 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.1 OAP62075.1 - 0.23 11.2 11.6 0.44 10.3 8.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 OAP62075.1 - 0.25 11.0 12.1 0.5 10.0 8.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 OAP62075.1 - 0.48 10.3 6.1 1.6 8.6 4.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.6 OAP62075.1 - 0.5 10.0 6.7 0.93 9.2 4.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC PF07967.8 OAP62079.1 - 2.9e-32 111.2 5.3 4.7e-29 100.8 0.0 3.2 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 OAP62079.1 - 8e-17 60.8 2.1 1.3e-15 57.0 0.2 3.0 3 0 0 3 3 3 1 Rsm1-like BIR PF00653.16 OAP62079.1 - 0.00026 21.3 1.4 0.024 15.0 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Mito_carr PF00153.22 OAP62080.1 - 5.7e-56 186.2 2.1 9.3e-20 70.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Atx10homo_assoc PF09759.4 OAP62081.1 - 1.4e-27 95.4 0.1 2.6e-26 91.3 0.0 2.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain zf-H2C2_2 PF13465.1 OAP62082.1 - 7.5e-05 22.8 1.9 7.5e-05 22.8 1.3 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP62082.1 - 0.00014 21.9 25.0 0.01 16.1 1.8 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 OAP62082.1 - 0.00083 19.4 5.9 0.0017 18.4 4.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 OAP62082.1 - 0.0019 18.3 1.0 0.0019 18.3 0.7 4.0 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 OAP62082.1 - 0.0031 17.7 23.5 0.033 14.5 2.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type TIR PF01582.15 OAP62082.1 - 0.098 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 TIR domain DUF629 PF04780.7 OAP62082.1 - 5.1 5.5 5.6 9.6 4.5 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF629) adh_short PF00106.20 OAP62083.1 - 7e-15 55.3 0.2 9.4e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP62083.1 - 7.4e-10 39.0 0.1 8.5e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP62083.1 - 1.5e-05 24.5 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 OAP62083.1 - 0.0028 17.3 0.3 0.0052 16.4 0.2 1.4 1 1 0 1 1 1 1 KR domain Herpes_capsid PF06112.6 OAP62084.1 - 0.73 9.8 5.4 2 8.4 3.7 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DIOX_N PF14226.1 OAP62085.1 - 1.8e-18 67.1 0.0 3.9e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP62085.1 - 6.1e-13 48.9 0.1 1.7e-12 47.4 0.0 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily NUDE_C PF04880.8 OAP62086.1 - 9.8e-22 78.0 6.5 9.8e-22 78.0 4.5 4.4 2 1 0 3 3 1 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 OAP62086.1 - 0.0039 15.7 31.3 0.0053 15.2 21.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 OAP62086.1 - 0.088 12.6 41.6 0.29 10.9 19.1 3.4 2 1 1 3 3 3 0 Tropomyosin like IncA PF04156.9 OAP62086.1 - 0.41 10.2 35.4 2.2 7.8 17.5 2.9 2 1 1 3 3 3 0 IncA protein AAA_13 PF13166.1 OAP62086.1 - 0.75 8.1 20.3 1.1 7.5 14.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 OAP62086.1 - 2.1 5.5 28.1 3.2 4.9 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 OAP62086.1 - 2.3 5.9 15.9 3.9 5.2 11.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.4 OAP62086.1 - 2.9 6.1 13.8 4.2 5.6 9.6 1.1 1 0 0 1 1 1 0 Peptidase S46 ATG16 PF08614.6 OAP62086.1 - 3.2 7.5 33.8 2.5 7.8 21.4 2.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 OAP62086.1 - 4 7.7 36.7 0.31 11.3 6.6 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 OAP62086.1 - 4.4 7.0 37.4 2.5 7.8 11.0 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.3 OAP62086.1 - 5.8 5.8 15.8 0.17 10.8 2.4 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF972 PF06156.8 OAP62086.1 - 9.2 6.6 25.4 0.16 12.3 5.3 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Isochorismatase PF00857.15 OAP62087.1 - 3.7e-48 163.7 0.0 4.6e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family NUC153 PF08159.7 OAP62088.1 - 1.2e-13 50.4 0.4 3.2e-13 49.0 0.3 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 OAP62088.1 - 0.00073 19.3 0.0 9.4 6.2 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Med13_C PF06333.7 OAP62089.1 - 1.7e-73 247.5 0.9 2.5e-73 247.0 0.0 1.7 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal MFS_1 PF07690.11 OAP62090.1 - 1.4e-14 53.6 50.6 6.5e-14 51.4 34.0 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP62090.1 - 5.2e-07 28.2 22.3 7.9e-07 27.6 15.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) dCMP_cyt_deam_1 PF00383.17 OAP62093.1 - 1.3e-26 92.2 1.4 1.8e-26 91.7 1.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 OAP62094.1 - 2.7e-05 24.9 0.0 5.6e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP62094.1 - 0.00017 21.9 0.0 0.00042 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAP62094.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.2 1 1 0 1 1 1 0 AAA domain FAM75 PF14650.1 OAP62094.1 - 0.055 12.8 0.5 0.063 12.6 0.3 1.1 1 0 0 1 1 1 0 FAM75 family CoaE PF01121.15 OAP62094.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase Lambda_CIII PF02061.11 OAP62094.1 - 0.061 13.3 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Lambda Phage CIII ThiF PF00899.16 OAP62095.1 - 2.5e-29 101.8 0.0 4.7e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 OAP62095.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FtsJ PF01728.14 OAP62096.1 - 1.3e-58 197.9 0.0 1.6e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 OAP62096.1 - 0.00039 20.1 0.0 0.0019 17.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP62096.1 - 0.049 14.2 0.0 0.16 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF3538 PF12057.3 OAP62097.1 - 0.037 13.6 0.1 0.079 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) DUF4611 PF15387.1 OAP62097.1 - 1.2 9.3 10.8 0.075 13.1 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-F_leu_zip PF10473.4 OAP62098.1 - 0.0017 18.2 42.6 0.22 11.3 7.7 3.2 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 OAP62098.1 - 0.0039 15.0 29.5 0.0048 14.7 20.5 1.1 1 0 0 1 1 1 1 HOOK protein DUF972 PF06156.8 OAP62098.1 - 0.0051 17.1 29.6 0.11 12.8 4.6 3.6 1 1 2 3 3 3 2 Protein of unknown function (DUF972) HsbA PF12296.3 OAP62098.1 - 0.0068 16.2 0.3 0.0068 16.2 0.2 2.1 2 1 0 2 2 2 1 Hydrophobic surface binding protein A Filament PF00038.16 OAP62098.1 - 0.022 14.2 32.7 0.086 12.2 11.3 2.3 1 1 1 2 2 2 0 Intermediate filament protein GAS PF13851.1 OAP62098.1 - 0.024 13.8 32.5 0.018 14.2 14.8 2.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 OAP62098.1 - 0.06 12.5 10.4 0.31 10.1 1.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 OAP62098.1 - 0.095 12.7 30.8 0.033 14.2 3.3 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 OAP62098.1 - 0.11 12.3 14.1 4.2 7.3 0.1 4.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) WEMBL PF05701.6 OAP62098.1 - 0.68 8.3 40.6 0.39 9.1 11.2 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light COG2 PF06148.6 OAP62098.1 - 1 9.2 16.4 0.38 10.6 1.7 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 OAP62098.1 - 1.2 8.9 36.2 3.3 7.4 6.8 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2408 PF10303.4 OAP62098.1 - 1.4 9.0 17.8 0.88 9.6 1.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Rab5-bind PF09311.6 OAP62098.1 - 1.4 8.7 38.6 1.3 8.8 23.3 2.6 1 1 1 2 2 2 0 Rabaptin-like protein AAA_13 PF13166.1 OAP62098.1 - 1.9 6.8 21.3 2.4 6.4 14.8 1.0 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 OAP62098.1 - 2.3 6.8 30.7 0.045 12.4 12.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF489 PF04356.7 OAP62098.1 - 2.7 7.5 11.2 0.47 10.0 3.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF489) ADIP PF11559.3 OAP62098.1 - 3.4 7.5 37.3 1.7 8.5 7.5 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 OAP62098.1 - 4.2 6.3 36.0 0.83 8.6 13.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Phage_Mu_Gam PF07352.7 OAP62098.1 - 4.3 6.8 16.6 0.22 11.0 6.4 2.5 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Baculo_PEP_C PF04513.7 OAP62098.1 - 5 6.9 14.6 2.5 7.9 4.5 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4522 PF15022.1 OAP62098.1 - 6.1 6.5 8.0 4.2 7.0 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4522) TMPIT PF07851.8 OAP62098.1 - 6.2 5.7 17.8 2.7 6.9 5.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF948 PF06103.6 OAP62098.1 - 7.4 6.5 7.9 28 4.6 1.3 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.6 OAP62098.1 - 7.5 6.3 34.2 0.99 9.1 11.6 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 OAP62098.1 - 8.5 6.3 40.4 0.9 9.5 12.0 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 OAP62098.1 - 9.1 6.0 12.5 13 5.6 0.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 OAP62098.1 - 9.9 6.6 29.3 9.4 6.7 4.9 4.2 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) MFS_1 PF07690.11 OAP62100.1 - 3.3e-38 131.3 21.8 4.7e-38 130.7 15.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM89 PF15098.1 OAP62100.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 TMEM89 protein family OST3_OST6 PF04756.8 OAP62102.1 - 1.2e-19 70.3 5.6 2.1e-19 69.6 3.9 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 OAP62102.1 - 0.0041 16.7 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF202 PF02656.10 OAP62102.1 - 3.6 7.8 5.7 57 4.0 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF2231 PF09990.4 OAP62102.1 - 6.6 7.1 7.7 23 5.4 0.4 2.9 4 0 0 4 4 4 0 Predicted membrane protein (DUF2231) GrpE PF01025.14 OAP62103.1 - 0.23 11.0 6.0 0.37 10.3 4.2 1.3 1 0 0 1 1 1 0 GrpE Prenyltrans PF00432.16 OAP62105.1 - 1.8e-27 94.5 13.2 1.7e-06 27.5 0.5 5.8 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAP62105.1 - 9.5e-21 74.3 0.0 5.2e-15 55.8 0.0 3.8 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAP62105.1 - 0.061 13.3 0.0 0.39 10.7 0.0 2.3 1 1 1 2 2 2 0 Prenyltransferase-like MarR PF01047.17 OAP62105.1 - 0.12 12.0 0.0 1 9.0 0.0 2.3 3 0 0 3 3 3 0 MarR family eIF3_subunit PF08597.5 OAP62106.1 - 1.6e-63 214.5 31.5 1.8e-63 214.3 21.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Peptidase_M56 PF05569.6 OAP62106.1 - 0.049 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 Rrn6 PF10214.4 OAP62106.1 - 0.44 8.5 4.6 0.67 7.9 3.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDK5_activator PF03261.10 OAP62106.1 - 2.6 7.2 11.4 0.17 11.1 3.5 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Enolase_C PF00113.17 OAP62107.1 - 6.7e-154 511.1 0.1 8.9e-154 510.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 OAP62107.1 - 1.9e-57 192.8 0.2 4e-57 191.8 0.1 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 OAP62107.1 - 0.0025 17.7 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 OAP62107.1 - 0.0055 15.6 0.5 0.15 10.9 0.1 2.6 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus VSP PF03302.8 OAP62107.1 - 0.085 11.4 0.2 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein AAA PF00004.24 OAP62108.1 - 4.5e-43 146.6 0.0 8.9e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAP62108.1 - 2.7e-07 30.7 0.0 9.3e-06 25.7 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 OAP62108.1 - 1.7e-06 27.8 0.1 4.2e-05 23.2 0.0 2.8 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAP62108.1 - 1.8e-06 28.0 0.0 6.6e-06 26.1 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 OAP62108.1 - 2.5e-06 27.6 0.0 0.00088 19.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 OAP62108.1 - 8e-06 25.0 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 OAP62108.1 - 0.00025 20.0 0.0 0.00081 18.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 OAP62108.1 - 0.00032 21.0 0.2 0.0074 16.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAP62108.1 - 0.00039 21.2 0.4 0.0011 19.8 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 OAP62108.1 - 0.00039 20.1 0.0 0.00096 18.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 OAP62108.1 - 0.0014 17.4 0.0 0.0024 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 OAP62108.1 - 0.0015 18.4 0.0 0.0055 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 OAP62108.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAP62108.1 - 0.0031 16.9 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 OAP62108.1 - 0.0037 16.4 0.0 0.0076 15.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 OAP62108.1 - 0.0051 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 OAP62108.1 - 0.0053 16.1 0.1 0.03 13.7 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 OAP62108.1 - 0.0068 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAP62108.1 - 0.0079 15.6 0.0 0.026 13.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 OAP62108.1 - 0.0094 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ResIII PF04851.10 OAP62108.1 - 0.015 15.1 0.1 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 OAP62108.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAP62108.1 - 0.02 14.5 0.3 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAP62108.1 - 0.026 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 OAP62108.1 - 0.027 13.6 0.4 0.1 11.6 0.0 2.1 3 0 0 3 3 3 0 KaiC HAUS-augmin3 PF14932.1 OAP62108.1 - 0.029 13.5 0.2 0.046 12.9 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Arch_ATPase PF01637.13 OAP62108.1 - 0.032 13.9 0.2 0.15 11.7 0.0 2.2 2 1 0 2 2 1 0 Archaeal ATPase UPF0079 PF02367.12 OAP62108.1 - 0.033 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Thymidylate_kin PF02223.12 OAP62108.1 - 0.036 13.4 0.0 2.5 7.4 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase PhoH PF02562.11 OAP62108.1 - 0.037 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF4200 PF13863.1 OAP62108.1 - 0.038 13.9 1.4 0.038 13.9 1.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Sigma54_activ_2 PF14532.1 OAP62108.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 OAP62108.1 - 0.05 12.4 0.1 0.58 8.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 OAP62108.1 - 0.052 13.1 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 OAP62108.1 - 0.085 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 eIF-1a PF01176.14 OAP62108.1 - 0.099 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Med3 PF11593.3 OAP62108.1 - 0.14 11.3 0.1 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_13 PF13166.1 OAP62108.1 - 0.21 10.0 2.3 7.7 4.8 0.2 2.7 2 1 1 3 3 3 0 AAA domain IncA PF04156.9 OAP62108.1 - 0.34 10.4 3.7 0.69 9.4 2.6 1.4 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 OAP62108.1 - 0.35 11.1 6.2 5.7 7.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF4482 PF14818.1 OAP62108.1 - 3 8.5 7.7 0.59 10.7 2.8 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4482) MFS_1 PF07690.11 OAP62109.1 - 1.3e-25 89.9 63.3 3.2e-20 72.1 29.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Suf PF05843.9 OAP62112.1 - 1.6e-05 24.7 3.3 0.0008 19.2 0.2 3.1 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 OAP62112.1 - 0.00013 22.5 0.5 0.051 14.2 0.0 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP62112.1 - 0.00014 22.1 3.6 8.9 7.2 0.2 6.5 6 2 3 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP62112.1 - 0.00067 19.9 1.6 28 5.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.11 OAP62112.1 - 1.1 9.0 19.1 13 5.6 0.0 6.7 7 1 0 7 7 7 0 HAT (Half-A-TPR) repeat SIS PF01380.17 OAP62113.1 - 6.2e-55 184.3 0.0 1.7e-29 102.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 OAP62113.1 - 1.1e-27 96.7 0.0 1.4e-18 66.7 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAP62113.1 - 4.2e-20 72.0 0.0 9.2e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 OAP62113.1 - 5.1e-13 48.8 0.0 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 OAP62113.1 - 9.3e-08 31.0 0.1 2.2e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 OAP62113.1 - 0.018 14.7 0.0 0.26 10.9 0.0 2.4 2 0 0 2 2 2 0 SIS domain Glyco_transf_22 PF03901.12 OAP62114.1 - 9.2e-75 252.2 19.9 1.1e-74 251.9 13.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family BCHF PF07284.6 OAP62114.1 - 0.81 9.5 7.6 0.043 13.6 0.5 2.3 3 0 0 3 3 3 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) ArfGap PF01412.13 OAP62115.1 - 1.4e-40 137.7 0.3 4.4e-40 136.1 0.2 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 OAP62115.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 OAP62115.1 - 0.077 12.5 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 CUE domain zf-Mss51 PF13824.1 OAP62116.1 - 0.23 11.3 6.1 0.28 11.0 0.9 3.1 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn-ribbon_8 PF09723.5 OAP62116.1 - 0.24 11.3 1.5 0.5 10.3 1.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 OAP62116.1 - 3.3 7.3 5.3 14 5.3 3.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Proteasome PF00227.21 OAP62117.1 - 1.9e-45 154.5 0.0 9.7e-32 109.7 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 OAP62117.1 - 8.7e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DMRL_synthase PF00885.14 OAP62118.1 - 1.7e-41 141.2 1.2 2.7e-23 82.2 0.1 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Aminotran_3 PF00202.16 OAP62119.1 - 1.4e-106 356.1 0.0 1.8e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 OAP62119.1 - 0.0021 17.0 0.0 0.0039 16.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAP62119.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase XdhC_C PF13478.1 OAP62120.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 XdhC Rossmann domain Glycophorin_A PF01102.13 OAP62120.1 - 3.3 7.5 6.5 0.47 10.2 1.0 1.8 2 0 0 2 2 2 0 Glycophorin A Syja_N PF02383.13 OAP62123.1 - 6.3e-84 281.4 0.0 1.4e-83 280.3 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.18 OAP62123.1 - 4e-23 82.6 0.0 7.5e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_11 PF13414.1 OAP62125.1 - 2.1e-07 30.4 0.7 4.4e-05 23.0 0.1 3.5 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.1 OAP62125.1 - 1.1e-06 28.7 0.8 0.17 12.6 0.0 5.0 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP62125.1 - 2.7e-06 26.8 0.0 0.0004 20.0 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAP62125.1 - 0.00029 20.6 1.3 0.41 10.5 0.0 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAP62125.1 - 0.0025 17.3 0.3 0.023 14.2 0.0 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP62125.1 - 0.0026 18.3 0.4 4.7 8.0 0.0 3.4 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAP62125.1 - 0.0053 16.8 0.0 2.5 8.5 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 OAP62125.1 - 0.012 15.7 0.0 0.045 13.8 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TOM20_plant PF06552.7 OAP62125.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_19 PF14559.1 OAP62125.1 - 0.036 14.3 0.0 1.2 9.4 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAP62125.1 - 0.072 12.8 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat HrpJ PF07201.6 OAP62125.1 - 0.097 12.6 1.3 0.3 11.1 0.0 2.3 2 1 0 2 2 2 0 HrpJ-like domain Adaptin_N PF01602.15 OAP62126.1 - 1.7e-85 287.3 0.1 2.2e-85 286.9 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAP62126.1 - 0.00039 20.3 0.2 0.15 11.9 0.0 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 OAP62126.1 - 0.0015 18.4 0.1 3.9 7.8 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat IF4E PF01652.13 OAP62129.1 - 1.5e-60 203.4 0.5 1.8e-60 203.2 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 OAP62130.1 - 1.2e-26 92.1 0.2 1.9e-26 91.4 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.15 OAP62131.1 - 2.9e-28 97.4 1.6 2.9e-28 97.4 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 OAP62131.1 - 1.1e-21 75.8 0.0 2.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain SAP18 PF06487.7 OAP62131.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) DUF3843 PF12954.2 OAP62132.1 - 0.045 12.7 0.3 0.053 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Muted PF14942.1 OAP62132.1 - 0.057 13.2 0.7 0.076 12.8 0.5 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Colicin PF01024.14 OAP62132.1 - 0.057 12.9 1.5 0.078 12.5 1.0 1.2 1 0 0 1 1 1 0 Colicin pore forming domain DUF2057 PF09829.4 OAP62132.1 - 0.098 12.3 1.2 0.23 11.0 0.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) XH PF03469.9 OAP62133.1 - 0.0073 15.9 14.8 0.95 9.1 0.2 4.3 2 1 1 4 4 4 2 XH domain Apolipoprotein PF01442.13 OAP62133.1 - 0.0077 15.7 15.2 0.84 9.1 7.5 3.3 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain YvbH_ext PF11724.3 OAP62133.1 - 0.037 13.7 0.2 0.23 11.1 0.2 2.3 2 0 0 2 2 2 0 YvbH-like oligomerisation region HisKA_3 PF07730.8 OAP62133.1 - 0.092 13.0 1.3 16 5.9 0.1 4.1 4 1 1 5 5 4 0 Histidine kinase Senescence PF06911.7 OAP62133.1 - 0.14 11.8 9.3 6.7 6.3 0.0 4.3 4 2 0 4 4 4 0 Senescence-associated protein Laminin_II PF06009.7 OAP62133.1 - 0.17 11.6 12.7 0.45 10.2 0.2 4.0 2 2 1 4 4 4 0 Laminin Domain II Phasin_2 PF09361.5 OAP62133.1 - 0.25 11.3 10.9 12 6.0 0.1 4.9 4 2 0 4 4 4 0 Phasin protein DUF2937 PF11157.3 OAP62133.1 - 0.33 10.2 3.5 13 5.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Alpha-E PF04168.7 OAP62133.1 - 0.41 9.9 1.6 3.4 6.9 0.0 2.8 4 0 0 4 4 4 0 A predicted alpha-helical domain with a conserved ER motif. DUF643 PF04867.7 OAP62133.1 - 2.3 8.6 16.2 2.5 8.5 0.9 3.7 3 3 0 3 3 3 0 Protein of unknown function (DUF643) IL34 PF15036.1 OAP62133.1 - 3 7.3 6.4 34 3.9 0.1 3.9 2 2 2 4 4 4 0 Interleukin 34 ApoC-I PF04691.7 OAP62133.1 - 4 7.2 13.6 10 5.8 0.0 4.8 5 1 0 5 5 5 0 Apolipoprotein C-I (ApoC-1) SRP_SPB PF02978.14 OAP62133.1 - 4.2 7.6 9.6 1.1 9.4 0.3 3.9 2 1 2 4 4 4 0 Signal peptide binding domain Dynamin_M PF01031.15 OAP62133.1 - 4.5 5.9 8.7 9.4 4.9 1.9 3.5 3 1 0 3 3 3 0 Dynamin central region FlgN PF05130.7 OAP62133.1 - 9.7 6.4 15.2 7.3 6.8 3.6 3.3 2 1 1 3 3 3 0 FlgN protein GST_N_2 PF13409.1 OAP62134.1 - 1.5e-16 60.1 0.0 3.3e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP62134.1 - 3.4e-12 46.0 0.0 8.6e-12 44.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP62134.1 - 9.1e-06 26.0 0.0 1.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAP62134.1 - 0.0013 18.6 0.0 0.0033 17.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP62134.1 - 0.022 14.9 0.0 0.39 10.9 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain LIM PF00412.17 OAP62135.1 - 1.6e-14 53.7 14.1 6.7e-09 35.6 3.4 2.3 2 0 0 2 2 2 2 LIM domain NAD_binding_5 PF07994.7 OAP62136.1 - 1.2e-113 379.5 0.3 1.4e-113 379.2 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 OAP62136.1 - 6.8e-46 154.7 0.9 6.8e-46 154.7 0.6 2.0 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase DUF1459 PF07312.6 OAP62136.1 - 0.083 12.8 0.3 0.48 10.3 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) Asp_Glu_race PF01177.17 OAP62137.1 - 1.5e-12 47.8 2.3 3.1e-11 43.6 1.6 2.1 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase FAM110_C PF14160.1 OAP62137.1 - 0.097 13.6 0.3 0.19 12.6 0.2 1.4 1 0 0 1 1 1 0 Centrosome-associated C terminus SLAC1 PF03595.12 OAP62138.1 - 4e-78 262.3 48.0 4.7e-78 262.1 33.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MLTD_N PF06474.7 OAP62139.1 - 0.011 15.8 0.2 0.011 15.8 0.2 1.8 2 0 0 2 2 2 0 MltD lipid attachment motif PIN_4 PF13638.1 OAP62140.1 - 0.028 14.5 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 PIN domain PSP PF04046.11 OAP62140.1 - 0.074 12.4 0.1 0.25 10.7 0.1 1.9 1 0 0 1 1 1 0 PSP UPF0183 PF03676.9 OAP62141.1 - 8.1e-37 126.7 0.0 1.3e-26 93.1 0.0 3.9 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 OAP62142.1 - 5.6e-109 363.8 0.2 5.6e-109 363.8 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 OAP62142.1 - 3.6e-09 36.9 1.4 3.6e-09 36.9 1.0 4.1 4 1 0 4 4 4 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.7 OAP62142.1 - 0.0012 18.6 0.4 0.0012 18.6 0.3 4.6 4 1 1 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 OAP62142.1 - 0.0037 16.8 17.9 0.0037 16.8 12.4 3.2 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain FAM92 PF06730.6 OAP62142.1 - 0.0047 16.2 4.3 0.0047 16.2 3.0 2.7 2 1 1 3 3 3 1 FAM92 protein MecA_N PF05223.6 OAP62142.1 - 0.76 9.8 7.4 12 6.0 0.2 2.7 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain SnoaL_4 PF13577.1 OAP62144.1 - 2.6e-07 30.5 0.9 3.7e-07 30.0 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 OAP62144.1 - 0.061 13.5 0.3 0.095 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 OAP62144.1 - 0.074 13.4 0.7 0.12 12.7 0.5 1.3 1 0 0 1 1 1 0 SnoaL-like domain P3A PF08727.6 OAP62145.1 - 0.14 11.5 0.8 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Poliovirus 3A protein like Y_phosphatase PF00102.22 OAP62146.1 - 2.3e-49 167.8 0.0 1.1e-22 80.5 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 OAP62146.1 - 0.032 14.4 0.0 0.085 13.1 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 OAP62146.1 - 0.089 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain GATA PF00320.22 OAP62147.1 - 8.5e-15 53.8 5.2 1.6e-14 52.8 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 OAP62147.1 - 0.24 11.4 1.9 0.51 10.3 1.3 1.5 1 0 0 1 1 1 0 zinc-finger Acetyltransf_1 PF00583.19 OAP62148.1 - 3.3e-05 23.8 0.0 6.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 OAP62148.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 OAP62148.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 OAP62149.1 - 2e-29 102.2 0.2 2.8e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP62149.1 - 2.8e-07 30.3 9.0 4.4e-07 29.7 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin PF00022.14 OAP62150.1 - 9.2e-118 393.0 0.0 1.1e-117 392.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAP62150.1 - 0.05 12.1 0.0 0.19 10.3 0.0 1.9 1 1 0 1 1 1 0 MreB/Mbl protein Pap_E4 PF02711.9 OAP62151.1 - 0.069 13.9 1.1 0.069 13.9 0.8 2.6 3 0 0 3 3 3 0 E4 protein DUF2217 PF10265.4 OAP62151.1 - 6.1 5.4 12.8 3.4 6.3 7.4 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SQS_PSY PF00494.14 OAP62152.1 - 2.9e-38 131.7 0.0 4.6e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF2207 PF09972.4 OAP62152.1 - 0.065 11.8 0.0 0.097 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DnaJ-X PF14308.1 OAP62153.1 - 2.7e-74 248.8 2.6 2.7e-74 248.8 1.8 2.7 4 0 0 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.26 OAP62153.1 - 6.5e-25 86.6 0.5 1.8e-24 85.2 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain OrfB_IS605 PF01385.14 OAP62153.1 - 0.0097 15.3 2.6 0.03 13.7 1.8 1.8 1 0 0 1 1 1 1 Probable transposase Homeobox PF00046.24 OAP62153.1 - 0.027 14.0 0.9 0.067 12.8 0.6 1.6 1 0 0 1 1 1 0 Homeobox domain IMS PF00817.15 OAP62155.1 - 3.7e-42 143.6 1.5 5.3e-42 143.1 0.4 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 OAP62155.1 - 1.7e-16 60.3 0.1 4.7e-16 58.8 0.1 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 OAP62155.1 - 2.4e-05 24.1 0.0 6.8e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif VPS28 PF03997.7 OAP62155.1 - 0.045 13.3 0.2 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 VPS28 protein EamA PF00892.15 OAP62156.1 - 3.1e-11 43.3 30.7 8.7e-06 25.7 3.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 OAP62156.1 - 3.5e-05 23.9 0.7 3.5e-05 23.9 0.5 2.7 2 0 0 2 2 2 1 Multidrug resistance efflux transporter PgaD PF13994.1 OAP62156.1 - 0.027 13.9 0.2 0.027 13.9 0.1 2.8 2 2 1 3 3 3 0 PgaD-like protein IncA PF04156.9 OAP62156.1 - 0.066 12.7 0.0 2.1 7.9 0.0 2.8 3 0 0 3 3 3 0 IncA protein TPT PF03151.11 OAP62156.1 - 0.3 10.7 26.0 0.18 11.4 0.8 3.0 3 0 0 3 3 3 0 Triose-phosphate Transporter family UPF0546 PF10639.4 OAP62156.1 - 3.1 7.6 12.7 2 8.2 0.9 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 FAD_binding_4 PF01565.18 OAP62157.1 - 5.8e-16 58.2 0.1 1e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAP62157.1 - 0.00017 21.4 0.4 0.00049 19.9 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like GMC_oxred_N PF00732.14 OAP62158.1 - 8.3e-59 199.1 0.0 1.1e-58 198.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP62158.1 - 1.1e-35 123.0 0.0 1.9e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAP62158.1 - 4.9e-05 23.2 0.0 0.00017 21.5 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP62158.1 - 9.9e-05 21.4 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP62158.1 - 0.00019 20.4 0.0 0.01 14.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP62158.1 - 0.00087 19.4 0.1 0.089 12.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP62158.1 - 0.0013 17.6 0.1 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP62158.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Aldo_ket_red PF00248.16 OAP62159.1 - 3.9e-52 176.8 0.0 4.5e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Alpha_L_fucos PF01120.12 OAP62159.1 - 0.095 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase FHA PF00498.21 OAP62160.1 - 2.2e-10 40.5 0.6 6.6e-10 38.9 0.1 2.0 2 0 0 2 2 2 1 FHA domain OAF PF14941.1 OAP62160.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, Out at first RPEL PF02755.10 OAP62161.1 - 2.7e-25 86.9 25.3 3.5e-09 35.6 0.7 3.7 4 0 0 4 4 4 3 RPEL repeat CRC_subunit PF08624.5 OAP62161.1 - 0.13 12.2 0.3 0.41 10.5 0.1 1.9 1 1 1 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit DUF1992 PF09350.5 OAP62161.1 - 0.52 10.1 3.8 21 5.0 2.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1992) V_ATPase_I PF01496.14 OAP62161.1 - 2 6.1 5.4 2.1 6.0 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Translin PF01997.11 OAP62162.1 - 1.1e-55 188.3 0.2 1.3e-55 188.0 0.1 1.0 1 0 0 1 1 1 1 Translin family EIF_2_alpha PF07541.7 OAP62162.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit HHH_6 PF14579.1 OAP62162.1 - 0.11 12.5 0.3 0.48 10.4 0.0 2.1 2 1 0 2 2 2 0 Helix-hairpin-helix motif Flu_NS2 PF00601.14 OAP62162.1 - 0.18 12.0 0.8 18 5.6 0.1 2.4 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Mannosyl_trans PF05007.8 OAP62163.1 - 2.1e-74 250.4 16.9 3.1e-74 249.8 11.7 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 OAP62163.1 - 9.3e-10 37.9 9.7 9.3e-10 37.9 6.7 2.2 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Bac_rhodopsin PF01036.13 OAP62166.1 - 2.1e-52 177.6 18.2 2.5e-52 177.3 12.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF805 PF05656.9 OAP62166.1 - 2.4 8.0 19.1 2.6 7.8 6.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF805) tRNA-synt_1 PF00133.17 OAP62167.1 - 3e-150 501.0 0.0 4e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAP62167.1 - 7e-21 74.3 0.0 8.7e-12 44.3 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 OAP62167.1 - 5.3e-20 71.7 0.3 9.8e-20 70.8 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 OAP62167.1 - 0.0052 15.9 0.0 0.88 8.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.9 OAP62167.1 - 0.064 12.9 5.0 0.28 10.8 3.5 2.1 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 OAP62167.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 HET PF06985.6 OAP62168.1 - 3.5e-06 27.2 0.2 0.006 16.7 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NPR3 PF03666.8 OAP62169.1 - 3.7 5.9 3.9 3.7 5.9 1.8 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF805 PF05656.9 OAP62169.1 - 4.9 7.0 6.3 0.7 9.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Rhodanese PF00581.15 OAP62171.1 - 5.6e-17 62.1 0.0 2.6e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Peptidase_M24 PF00557.19 OAP62172.1 - 1.9e-45 155.0 0.1 2.3e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 OAP62172.1 - 2.4e-05 24.0 4.9 7.1e-05 22.5 3.4 1.9 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 OAP62172.1 - 0.062 12.9 4.7 0.16 11.6 3.2 1.7 1 0 0 1 1 1 0 HIT zinc finger ZZ PF00569.12 OAP62173.1 - 1.7e-11 43.4 6.3 2.8e-11 42.7 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 OAP62173.1 - 1.7e-10 39.4 5.2 0.0002 20.4 0.3 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 OAP62173.1 - 1e-08 35.1 3.2 1e-08 35.1 2.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 OAP62173.1 - 1.3e-08 34.0 3.6 0.0016 18.1 0.4 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 OAP62173.1 - 0.00019 20.6 6.6 0.19 11.1 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 OAP62173.1 - 0.00033 20.2 2.9 0.18 11.4 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair DUF4519 PF15012.1 OAP62173.1 - 0.35 10.8 1.0 0.75 9.7 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) zf-B_box PF00643.19 OAP62173.1 - 1.2 9.0 7.1 2 8.3 4.9 1.3 1 0 0 1 1 1 0 B-box zinc finger C1_3 PF07649.7 OAP62173.1 - 4.4 7.4 9.0 7.2 6.7 6.3 1.4 1 0 0 1 1 1 0 C1-like domain WD40 PF00400.27 OAP62175.1 - 5.9e-21 73.5 13.3 1.2e-08 34.5 0.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 OAP62175.1 - 0.0037 16.5 0.0 0.0092 15.2 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity IKI3 PF04762.7 OAP62175.1 - 0.13 10.0 0.0 1.4 6.5 0.0 2.3 2 1 0 2 2 2 0 IKI3 family MutS_V PF00488.16 OAP62176.1 - 2.4e-75 252.9 0.0 4.6e-75 252.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAP62176.1 - 1.2e-33 116.5 3.0 2.4e-33 115.6 2.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 OAP62176.1 - 3.2e-12 46.6 0.1 9.5e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 OAP62176.1 - 1.8e-09 37.6 1.3 4.7e-09 36.3 0.9 1.8 1 0 0 1 1 1 1 MutS family domain IV NOA36 PF06524.7 OAP62176.1 - 1.2 8.2 7.0 2.5 7.2 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.27 OAP62177.1 - 1.8e-91 297.0 29.7 2.1e-16 59.0 0.3 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 OAP62177.1 - 5.9e-07 29.3 0.0 0.053 13.2 0.0 3.0 2 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 OAP62177.1 - 1.3e-06 26.8 13.6 0.053 11.6 0.7 6.0 2 2 3 6 6 6 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 OAP62177.1 - 0.00028 20.1 0.5 3.8 6.5 0.0 3.8 4 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal NLE PF08154.7 OAP62177.1 - 0.00039 20.3 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain IKI3 PF04762.7 OAP62177.1 - 0.00092 17.1 0.4 1.7 6.3 0.1 3.1 2 1 1 3 3 3 3 IKI3 family RRN7 PF11781.3 OAP62177.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Proteasome_A_N PF10584.4 OAP62177.1 - 0.14 11.4 0.3 18 4.7 0.0 3.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 OAP62177.1 - 0.15 11.8 1.6 5.9 6.6 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cytochrom_C1 PF02167.10 OAP62178.1 - 3.8e-82 275.1 0.0 4.8e-82 274.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 OAP62178.1 - 0.0063 16.6 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 OAP62178.1 - 0.077 13.8 0.6 0.27 12.0 0.2 2.2 2 1 0 2 2 2 0 Cytochrome c DUF221 PF02714.10 OAP62179.1 - 4.1e-98 328.2 16.1 4.1e-98 328.2 11.1 1.9 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAP62179.1 - 1.7e-40 138.1 0.9 1.7e-40 138.1 0.6 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAP62179.1 - 5.9e-19 68.3 0.3 1.2e-18 67.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 OAP62179.1 - 0.03 14.3 0.0 6.5 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 OAP62180.1 - 3.7e-10 39.3 0.9 3e-06 26.8 0.2 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 OAP62180.1 - 4.9e-09 35.6 0.3 0.001 18.6 0.1 2.7 2 0 0 2 2 2 2 F-box domain AAA_26 PF13500.1 OAP62181.1 - 4e-34 117.9 0.0 6.5e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_3 PF00202.16 OAP62181.1 - 4e-34 117.9 0.0 1.2e-22 80.2 0.0 3.2 3 1 0 3 3 3 2 Aminotransferase class-III CbiA PF01656.18 OAP62181.1 - 0.034 13.5 0.0 0.07 12.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAP62181.1 - 0.06 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain CAP18_C PF12153.3 OAP62182.1 - 0.05 13.2 0.5 0.14 11.8 0.3 1.8 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) Aminotran_1_2 PF00155.16 OAP62184.1 - 6.9e-44 150.2 0.0 8e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAP62184.1 - 2e-09 36.2 0.0 3e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 OAP62184.1 - 0.004 16.0 0.0 0.006 15.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 OAP62184.1 - 0.0054 15.8 0.0 0.018 14.1 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 OAP62184.1 - 0.014 14.2 0.0 0.095 11.4 0.0 2.0 2 1 0 2 2 2 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 OAP62184.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Sulfotransfer_3 PF13469.1 OAP62185.1 - 0.00036 21.4 1.5 0.0011 19.9 0.8 1.8 1 1 0 1 1 1 1 Sulfotransferase family IL22 PF14565.1 OAP62186.1 - 0.062 13.3 0.1 9.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Clp_N PF02861.15 OAP62186.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Clp amino terminal domain bZIP_1 PF00170.16 OAP62186.1 - 0.25 11.3 10.9 1.5 8.8 4.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor adh_short PF00106.20 OAP62187.1 - 1.8e-18 67.0 0.1 2.6e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62187.1 - 7e-09 35.6 0.1 1.1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP62187.1 - 0.00029 20.3 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP62187.1 - 0.0058 15.5 0.0 0.026 13.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Fungal_trans_2 PF11951.3 OAP62188.1 - 2.4e-21 75.7 3.3 3e-14 52.4 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP62188.1 - 1.4e-09 37.7 7.7 2.1e-09 37.1 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecm29 PF13001.2 OAP62189.1 - 8.4e-94 314.8 1.9 2.3e-93 313.3 1.3 1.8 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 OAP62189.1 - 0.016 15.2 8.1 40 4.6 0.0 7.6 10 0 0 10 10 10 0 HEAT repeat Ribosomal_S28e PF01200.13 OAP62190.1 - 2.3e-32 110.5 2.2 2.4e-32 110.4 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 OAP62191.1 - 9.7e-55 184.5 0.2 1.5e-54 184.0 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 OAP62191.1 - 6.3e-28 96.5 0.9 1.1e-27 95.7 0.1 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.6 OAP62191.1 - 0.015 14.8 0.0 0.026 14.1 0.0 1.5 1 1 0 1 1 1 0 NMT1/THI5 like Nit_Regul_Hom PF10126.4 OAP62191.1 - 0.047 13.4 0.6 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF2721 PF11026.3 OAP62192.1 - 0.011 15.3 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) RAMP PF04901.8 OAP62192.1 - 0.078 12.7 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Receptor activity modifying family Fcf1 PF04900.7 OAP62193.1 - 2.4e-41 139.9 1.9 2.5e-41 139.8 0.2 1.7 2 0 0 2 2 2 1 Fcf1 DUF2975 PF11188.3 OAP62194.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Herpes_gE PF02480.11 OAP62194.1 - 0.077 11.2 0.0 0.081 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ATP11 PF06644.6 OAP62195.1 - 9.8e-82 274.4 0.0 1.2e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Z1 PF10593.4 OAP62195.1 - 0.034 13.3 0.1 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Z1 domain Abhydrolase_5 PF12695.2 OAP62196.1 - 8.2e-24 84.0 0.0 1.1e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP62196.1 - 3.7e-20 72.8 0.0 5.1e-19 69.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAP62196.1 - 5.1e-11 41.6 0.0 4.2e-06 25.4 0.0 3.0 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 OAP62196.1 - 1.9e-07 30.9 0.0 0.00067 19.4 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 OAP62196.1 - 8.6e-07 28.7 0.0 0.0013 18.3 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 OAP62196.1 - 3.1e-05 23.6 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 OAP62196.1 - 0.00014 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 OAP62196.1 - 0.00016 20.9 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 OAP62196.1 - 0.00019 20.9 0.0 0.49 9.7 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 OAP62196.1 - 0.00046 19.7 0.1 0.055 12.8 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 OAP62196.1 - 0.00054 19.4 0.0 0.61 9.4 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 OAP62196.1 - 0.0027 17.0 0.0 0.71 9.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 OAP62196.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Acyl_transf_2 PF02273.10 OAP62196.1 - 0.026 13.5 0.0 0.064 12.2 0.0 1.5 2 0 0 2 2 2 0 Acyl transferase Lipase_3 PF01764.20 OAP62196.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF818 PF05677.7 OAP62196.1 - 0.063 11.9 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) UPF0227 PF05728.7 OAP62196.1 - 0.066 12.9 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.5 OAP62196.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Proteasome PF00227.21 OAP62197.1 - 9.5e-47 158.7 0.5 1.3e-46 158.2 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 OAP62197.1 - 1e-37 129.8 0.1 3.6e-22 79.3 0.1 2.4 2 0 0 2 2 2 2 Cyclin SNF2_N PF00176.18 OAP62198.1 - 1.1e-63 214.7 0.1 2.3e-63 213.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP62198.1 - 8.4e-13 47.9 0.0 2.6e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP62198.1 - 4.6e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 OAP62198.1 - 2.9e-05 23.6 6.4 2.9e-05 23.6 4.4 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP62198.1 - 0.00012 21.6 7.3 0.00012 21.6 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP62198.1 - 0.0011 18.7 7.6 0.0011 18.7 5.3 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP62198.1 - 0.0012 18.8 7.0 0.0012 18.8 4.8 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DUF4196 PF13846.1 OAP62198.1 - 0.018 15.3 2.4 0.018 15.3 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) Zn_Tnp_IS91 PF14319.1 OAP62198.1 - 0.091 12.2 13.5 0.082 12.4 1.0 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_UBOX PF13445.1 OAP62198.1 - 0.97 9.2 7.9 0.059 13.0 0.7 2.6 3 0 0 3 3 3 0 RING-type zinc-finger Chorion_2 PF03964.10 OAP62198.1 - 3.6 8.1 8.9 1.3 9.6 1.3 2.7 3 0 0 3 3 3 0 Chorion family 2 LRR_8 PF13855.1 OAP62199.1 - 0.0052 16.5 12.0 0.26 11.0 3.9 4.7 3 2 1 4 4 4 1 Leucine rich repeat INCENP_N PF12178.3 OAP62199.1 - 0.043 13.3 0.1 0.25 10.9 0.0 2.4 3 0 0 3 3 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal FYVE PF01363.16 OAP62199.1 - 0.11 12.4 0.9 0.39 10.6 0.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger LRR_4 PF12799.2 OAP62199.1 - 0.32 10.6 7.2 3.8 7.2 0.8 4.3 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) CDC45 PF02724.9 OAP62199.1 - 9.2 4.1 11.0 15 3.4 7.6 1.3 1 0 0 1 1 1 0 CDC45-like protein MutS_V PF00488.16 OAP62200.1 - 8.2e-88 293.7 0.1 1.5e-87 292.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAP62200.1 - 7.7e-39 133.5 0.6 1.6e-38 132.5 0.3 1.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 OAP62200.1 - 2.7e-28 98.2 0.2 6.8e-28 96.9 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 OAP62200.1 - 3.6e-09 36.8 0.0 9.6e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 OAP62200.1 - 7.7e-05 22.7 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV FAD_binding_3 PF01494.14 OAP62201.1 - 2.9e-22 79.1 0.0 8.6e-22 77.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 OAP62201.1 - 0.0012 18.6 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 OAP62201.1 - 0.0081 15.1 0.1 0.3 9.9 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP62201.1 - 0.073 13.1 0.0 0.54 10.2 0.0 2.4 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP62201.1 - 0.091 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 OAP62201.1 - 0.11 11.3 0.0 0.59 8.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.22 OAP62201.1 - 0.12 12.8 0.1 23 5.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BAF PF02961.9 OAP62202.1 - 0.04 14.2 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 Barrier to autointegration factor ubiquitin PF00240.18 OAP62203.1 - 0.0003 20.1 0.0 0.00075 18.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.20 OAP62204.1 - 7.6e-63 212.0 0.0 1e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP62204.1 - 8.6e-37 126.5 0.0 1.1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP62204.1 - 0.0016 17.4 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAP62204.1 - 0.054 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family IGR PF09597.5 OAP62205.1 - 3.6e-24 84.4 0.4 7.2e-24 83.4 0.3 1.5 1 0 0 1 1 1 1 IGR protein motif Med28 PF11594.3 OAP62205.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 Kinesin PF00225.18 OAP62206.1 - 8.9e-96 320.4 0.0 2.1e-95 319.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain TMF_DNA_bd PF12329.3 OAP62206.1 - 0.042 13.6 0.4 0.042 13.6 0.3 4.3 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 OAP62206.1 - 0.15 11.6 13.7 2.6 7.6 0.1 2.6 2 0 0 2 2 2 0 IncA protein DUF4407 PF14362.1 OAP62206.1 - 0.98 8.3 12.4 0.28 10.0 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2205 PF10224.4 OAP62206.1 - 4.3 6.9 12.4 14 5.3 4.4 3.1 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) RHS PF03527.9 OAP62207.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 RHS protein AMP-binding PF00501.23 OAP62208.1 - 1.4e-62 211.4 0.0 1.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP62208.1 - 1.4e-12 48.3 0.1 3.1e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YL1_C PF08265.6 OAP62208.1 - 0.15 11.6 0.2 0.39 10.3 0.1 1.7 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain DUF3812 PF12757.2 OAP62209.1 - 4.5e-35 120.3 15.5 4.5e-35 120.3 10.7 5.2 5 1 1 6 6 6 1 Protein of unknown function (DUF3812) Y_phosphatase3 PF13350.1 OAP62210.1 - 3.6e-28 98.8 0.0 1.1e-14 54.9 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 OAP62210.1 - 2.1e-06 27.1 0.0 6.6e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 OAP62210.1 - 0.00066 19.7 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 OAP62210.1 - 0.029 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Frag1 PF10277.4 OAP62211.1 - 2.9e-44 151.1 19.3 3.5e-44 150.8 13.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF687 PF05095.7 OAP62211.1 - 0.08 11.2 1.0 0.11 10.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) SLAC1 PF03595.12 OAP62211.1 - 0.46 9.0 20.4 3.7 6.1 14.1 1.9 1 1 0 1 1 1 0 Voltage-dependent anion channel DUF3533 PF12051.3 OAP62212.1 - 4.5e-73 246.2 7.5 5.3e-73 245.9 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DnaJ PF00226.26 OAP62213.1 - 8e-21 73.5 2.8 1.6e-20 72.6 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 OAP62213.1 - 0.0024 17.5 4.0 0.0043 16.7 2.8 1.5 1 1 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 OAP62213.1 - 0.011 15.7 0.2 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF1269 PF06897.7 OAP62213.1 - 0.029 14.3 0.5 0.059 13.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_Omp PF13488.1 OAP62213.1 - 0.062 12.9 6.2 0.11 12.2 4.3 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 OAP62213.1 - 0.1 12.0 7.6 0.18 11.3 5.3 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 OAP62213.1 - 1.2 9.2 8.6 2.6 8.2 6.0 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 OAP62213.1 - 2.6 7.7 12.2 4.7 6.9 8.5 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF605 PF04652.11 OAP62215.1 - 0.14 11.5 23.6 0.13 11.6 15.6 1.3 1 1 0 1 1 1 0 Vta1 like DUF4604 PF15377.1 OAP62215.1 - 5.3 7.2 14.0 0.32 11.1 3.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) PRA1 PF03208.14 OAP62216.1 - 4.1e-39 133.4 1.0 4.7e-39 133.1 0.7 1.1 1 0 0 1 1 1 1 PRA1 family protein DnaJ PF00226.26 OAP62217.1 - 2.9e-08 33.3 0.1 5.8e-08 32.3 0.1 1.6 1 1 0 1 1 1 1 DnaJ domain SpoIISA_toxin PF14171.1 OAP62217.1 - 0.22 10.7 0.1 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Fungal_trans_2 PF11951.3 OAP62218.1 - 0.018 13.6 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4415 PF14384.1 OAP62218.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4415) Cornichon PF03311.9 OAP62219.1 - 7.9e-46 155.3 4.6 9.3e-46 155.1 3.2 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 OAP62220.1 - 1.7e-39 132.2 8.0 2.1e-08 33.7 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 OAP62220.1 - 2.7e-06 27.0 0.0 5.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 OAP62220.1 - 0.01 14.2 0.0 0.02 13.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 OAP62220.1 - 0.039 12.0 0.0 0.07 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Sod_Fe_C PF02777.13 OAP62221.1 - 3.8e-15 55.6 0.3 5.4e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain CS PF04969.11 OAP62223.1 - 9.4e-18 64.5 0.1 1.9e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 CS domain Melibiase PF02065.13 OAP62224.1 - 1.6e-30 106.0 0.0 2.4e-14 52.8 0.0 2.1 1 1 1 2 2 2 2 Melibiase UbiA PF01040.13 OAP62225.1 - 4.4e-32 111.3 14.1 6.4e-32 110.7 9.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Med8 PF10232.4 OAP62226.1 - 1.5e-30 106.4 6.1 2.4e-30 105.7 4.2 1.3 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Sigma70_ner PF04546.8 OAP62226.1 - 1.3 8.5 7.5 2.2 7.8 5.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 OAP62226.1 - 1.5 6.6 7.9 1.8 6.3 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1678 PF07913.6 OAP62227.1 - 0.077 12.5 0.1 0.69 9.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1678) Acyl-CoA_dh_1 PF00441.19 OAP62228.1 - 2.9e-32 111.8 0.4 7e-32 110.6 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 OAP62228.1 - 6.1e-21 74.0 0.1 1.8e-20 72.4 0.1 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 OAP62228.1 - 1.4e-18 66.0 0.6 2.9e-18 65.1 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAP62228.1 - 2.2e-09 37.8 0.0 5.5e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAP62228.1 - 0.00014 22.1 0.0 0.00037 20.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PIG-S PF10510.4 OAP62229.1 - 4.6e-126 421.5 0.0 6e-126 421.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Amidase PF01425.16 OAP62229.1 - 3.4e-11 42.6 0.1 5.7e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Amidase Adhesin_P1 PF03257.8 OAP62229.1 - 0.29 11.4 1.8 1.6 9.1 0.0 2.9 4 0 0 4 4 4 0 Mycoplasma adhesin P1 Polyketide_cyc PF03364.15 OAP62230.1 - 1.9e-22 79.6 0.0 2.2e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 OAP62230.1 - 1.3e-05 25.4 0.1 1.5e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ATP1G1_PLM_MAT8 PF02038.11 OAP62231.1 - 2.2 7.3 5.3 1.1 8.3 0.2 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family 3Beta_HSD PF01073.14 OAP62233.1 - 6.1e-63 212.1 0.0 1.1e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP62233.1 - 1.7e-40 138.9 0.0 2.3e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP62233.1 - 7.8e-23 80.6 0.0 1e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 OAP62233.1 - 1.4e-17 63.5 0.0 3.1e-17 62.3 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 OAP62233.1 - 4.5e-15 55.9 0.0 7e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62233.1 - 6.4e-13 48.7 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP62233.1 - 1.5e-12 47.0 0.0 1e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAP62233.1 - 1.6e-11 44.5 0.1 5.4e-11 42.8 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 OAP62233.1 - 0.0019 17.2 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 OAP62233.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 OAP62233.1 - 0.011 15.6 1.0 0.027 14.4 0.0 2.3 3 0 0 3 3 3 0 TrkA-N domain Spt5-NGN PF03439.8 OAP62234.1 - 7.9e-24 83.2 0.0 1.7e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 OAP62234.1 - 3.2e-15 56.5 10.7 3.2e-15 56.5 7.4 5.2 4 2 1 5 5 5 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 OAP62234.1 - 7e-15 55.5 50.1 4.1e-11 43.3 27.7 4.6 2 1 2 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 OAP62234.1 - 1.1e-06 28.0 13.3 0.0058 16.3 0.0 5.0 5 0 0 5 5 5 2 KOW motif Antimicrobial_5 PF08026.6 OAP62234.1 - 9.1 6.2 9.9 3.6 7.5 1.8 3.5 2 1 1 3 3 3 0 Bee antimicrobial peptide Aldedh PF00171.17 OAP62235.1 - 2.2e-185 616.4 0.1 2.5e-185 616.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 OAP62235.1 - 0.02 14.1 0.0 0.092 11.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) IPI_T4 PF11634.3 OAP62235.1 - 0.061 13.2 0.0 6.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 EVE PF01878.13 OAP62236.1 - 9.5e-51 171.5 0.0 1.4e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 EVE domain Med3 PF11593.3 OAP62236.1 - 0.12 11.5 1.8 0.18 10.9 1.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal bZIP_2 PF07716.10 OAP62237.1 - 0.00058 19.6 5.6 0.0012 18.6 3.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 OAP62237.1 - 0.21 11.5 6.2 0.36 10.7 4.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor SGL PF08450.7 OAP62238.1 - 2.3e-69 233.4 0.1 2.8e-69 233.2 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DUF3848 PF12959.2 OAP62239.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) DUF1062 PF06353.7 OAP62239.1 - 0.038 14.2 0.1 0.046 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) Pup PF05639.6 OAP62239.1 - 0.56 10.7 7.6 1.3 9.6 1.0 2.7 2 1 1 3 3 3 0 Pup-like protein TT_ORF2 PF02957.10 OAP62239.1 - 4.3 8.0 5.7 1.6 9.4 1.2 1.9 1 1 1 2 2 2 0 TT viral ORF2 DAHP_synth_2 PF01474.11 OAP62240.1 - 3e-183 609.1 0.0 8.8e-148 492.3 0.0 2.0 2 0 0 2 2 2 2 Class-II DAHP synthetase family Glyco_hydro_17 PF00332.13 OAP62242.1 - 7.1e-05 21.9 0.6 0.0017 17.4 0.5 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 OAP62242.1 - 0.0093 14.7 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Acyl-CoA_dh_1 PF00441.19 OAP62243.1 - 1.1e-39 135.9 0.4 1.5e-39 135.4 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP62243.1 - 1.2e-20 72.7 0.2 2e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAP62243.1 - 4.3e-18 65.9 0.0 1.2e-17 64.5 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 OAP62243.1 - 1.7e-17 62.9 0.2 2.9e-17 62.2 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 OAP62243.1 - 4.6e-08 33.3 0.0 7.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Kelch_3 PF13415.1 OAP62244.1 - 1.7e-19 69.4 5.8 1.7e-10 40.7 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 OAP62244.1 - 5.7e-19 67.6 5.2 9.8e-09 34.8 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 OAP62244.1 - 3.8e-12 45.8 5.0 3e-05 23.8 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 OAP62244.1 - 3.6e-10 39.5 9.6 0.0081 16.2 0.6 5.8 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 OAP62244.1 - 2.9e-09 36.3 1.8 1.5e-05 24.5 0.0 4.8 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 OAP62244.1 - 1.8e-08 33.7 0.0 0.0057 16.1 0.0 3.8 3 0 0 3 3 3 2 Kelch motif BTB PF00651.26 OAP62244.1 - 0.0012 18.8 0.0 0.048 13.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain AhpC-TSA PF00578.16 OAP62245.1 - 3.7e-33 113.8 0.0 5.2e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAP62245.1 - 9.8e-14 51.1 0.0 1.3e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 OAP62245.1 - 4.6e-12 45.3 0.3 8.7e-12 44.4 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ank_2 PF12796.2 OAP62246.1 - 2e-16 60.0 0.0 2.7e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAP62246.1 - 5.1e-15 54.4 0.4 4e-09 35.8 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 OAP62246.1 - 2.5e-14 52.9 2.5 2.6e-07 30.6 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP62246.1 - 4e-11 42.0 0.0 6.1e-05 22.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 OAP62246.1 - 2.4e-10 40.6 0.1 5.6e-05 23.5 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) GMC_oxred_N PF00732.14 OAP62248.1 - 1.7e-68 230.9 0.0 2.7e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP62248.1 - 4.2e-39 134.1 0.0 6.9e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP62248.1 - 1.6e-07 30.5 0.3 6e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP62248.1 - 6.6e-07 28.5 0.3 0.00024 20.0 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 OAP62248.1 - 0.00013 21.0 0.1 0.00019 20.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP62248.1 - 0.00013 21.9 0.2 0.0003 20.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP62248.1 - 0.00022 21.3 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP62248.1 - 0.00043 20.2 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP62248.1 - 0.0058 15.7 0.1 0.031 13.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Imm21 PF15569.1 OAP62248.1 - 0.0089 15.7 0.0 0.031 14.0 0.0 2.0 2 0 0 2 2 1 1 Immunity protein 21 HI0933_like PF03486.9 OAP62248.1 - 0.034 12.6 0.1 0.056 11.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GTP_EFTU PF00009.22 OAP62249.1 - 1.2e-55 187.8 0.4 2.3e-55 186.9 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 OAP62249.1 - 9.5e-34 115.0 0.0 2.4e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 OAP62249.1 - 2.1e-30 104.7 0.1 3.9e-30 103.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 OAP62249.1 - 7.8e-21 73.7 0.0 2.6e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAP62249.1 - 1.3e-12 47.5 0.1 4.4e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 OAP62249.1 - 0.035 13.6 0.1 0.12 11.8 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Methyltransf_3 PF01596.12 OAP62250.1 - 3.1e-28 98.2 0.0 4e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 OAP62250.1 - 2.3e-12 47.6 0.0 3.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP62250.1 - 7.4e-07 29.7 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP62250.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP62250.1 - 0.00024 20.7 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP62250.1 - 0.062 13.0 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 OAP62250.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Syja_N PF02383.13 OAP62251.1 - 1.8e-92 309.5 0.0 2.2e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 OAP62252.1 - 1.9e-59 199.7 0.4 2.1e-59 199.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP62252.1 - 1.5e-19 70.6 0.1 2.7e-19 69.7 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 OAP62252.1 - 5.9e-15 54.9 0.1 7.3e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAP62252.1 - 8.5e-08 31.8 0.1 1.5e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAP62252.1 - 1.9e-07 30.4 0.1 2.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAP62252.1 - 4.3e-06 26.6 0.0 5.8e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAP62252.1 - 0.005 16.9 0.1 0.89 9.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 OAP62252.1 - 0.03 13.5 0.2 0.11 11.6 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAP62252.1 - 0.032 14.2 0.1 0.12 12.3 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain Shikimate_DH PF01488.15 OAP62252.1 - 0.048 13.7 0.0 0.18 11.9 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAT PF03417.11 OAP62252.1 - 0.14 11.5 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TLD PF07534.11 OAP62253.1 - 4.4e-21 75.3 0.0 9.2e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 TLD Mur_ligase_M PF08245.7 OAP62254.1 - 7.1e-06 26.1 1.6 9.8e-05 22.4 1.1 2.4 1 1 0 1 1 1 1 Mur ligase middle domain Kelch_5 PF13854.1 OAP62255.1 - 1.3e-17 63.3 1.3 6.7e-14 51.4 0.1 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 OAP62255.1 - 0.00039 20.0 1.9 1 9.2 0.0 5.3 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 OAP62255.1 - 0.00046 20.2 2.0 0.087 13.0 0.1 4.3 4 0 0 4 4 4 1 Kelch motif Rax2 PF12768.2 OAP62255.1 - 0.0027 16.9 0.1 0.0092 15.2 0.0 1.9 2 0 0 2 2 2 1 Cortical protein marker for cell polarity SKG6 PF08693.5 OAP62255.1 - 0.0035 16.6 3.9 0.0085 15.3 2.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.20 OAP62255.1 - 0.079 12.5 5.6 0.88 9.1 0.1 4.2 4 1 0 4 4 4 0 Kelch motif EphA2_TM PF14575.1 OAP62255.1 - 0.15 12.4 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amidohydro_1 PF01979.15 OAP62257.1 - 1.4e-12 47.9 1.2 2.2e-12 47.2 0.8 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAP62257.1 - 1.5e-11 44.8 0.3 2.7e-10 40.7 0.2 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 OAP62257.1 - 8.1e-10 38.3 0.0 5.3e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP62257.1 - 0.0058 15.8 2.6 0.53 9.4 0.6 2.9 2 1 0 2 2 2 2 Amidohydrolase family ADH_zinc_N PF00107.21 OAP62257.1 - 0.089 12.3 0.1 0.26 10.8 0.1 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 OAP62258.1 - 4.9e-30 104.5 0.0 6.6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP62258.1 - 3.5e-07 30.2 0.0 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 OAP62258.1 - 6.7e-05 23.2 0.0 0.00017 21.9 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 OAP62258.1 - 0.00013 22.4 0.0 0.00022 21.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.10 OAP62258.1 - 0.00056 18.7 0.0 0.00068 18.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 OAP62258.1 - 0.00099 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 OAP62258.1 - 0.0041 16.4 0.0 0.028 13.7 0.0 2.2 1 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 OAP62258.1 - 0.014 14.8 0.0 0.052 13.0 0.0 1.8 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_3 PF03447.11 OAP62258.1 - 0.076 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 OAP62259.1 - 2e-37 129.3 0.0 2.3e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP62259.1 - 7.7e-23 80.8 0.2 4e-22 78.5 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62259.1 - 5.5e-22 78.4 0.1 2.3e-19 69.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 OAP62259.1 - 2.7e-07 31.0 0.0 3.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 OAP62259.1 - 3.4e-07 29.9 0.1 0.018 14.5 0.0 3.0 1 1 2 3 3 3 2 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 OAP62259.1 - 4.8e-07 29.5 0.2 0.00074 19.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase Hydrolase_4 PF12146.3 OAP62259.1 - 1.3e-06 28.1 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 OAP62259.1 - 1.4e-05 24.6 0.0 5.5e-05 22.7 0.0 2.0 2 1 0 2 2 2 1 Putative esterase PGAP1 PF07819.8 OAP62259.1 - 1.7e-05 24.5 0.1 0.00016 21.3 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 OAP62259.1 - 0.0001 21.6 0.1 0.0087 15.3 0.0 2.7 2 1 0 3 3 3 1 Dienelactone hydrolase family DUF915 PF06028.6 OAP62259.1 - 0.00015 20.9 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.9 OAP62259.1 - 0.00025 19.6 0.0 0.00029 19.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.8 OAP62259.1 - 0.00029 20.4 0.1 0.00052 19.6 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 OAP62259.1 - 0.00035 20.3 0.0 0.0012 18.6 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 OAP62259.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 OAP62259.1 - 0.043 13.5 0.0 0.063 12.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.2 OAP62259.1 - 0.06 12.2 0.5 0.87 8.4 0.0 2.6 3 1 1 4 4 4 0 Chlorophyllase enzyme DUF676 PF05057.9 OAP62259.1 - 0.078 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 OAP62259.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Phenol_Hydrox PF02332.13 OAP62260.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase Fungal_trans PF04082.13 OAP62261.1 - 2.3e-28 98.7 0.1 3.5e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP62261.1 - 4.1e-07 29.8 10.8 8.2e-07 28.8 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 OAP62261.1 - 0.26 10.9 2.7 0.49 9.9 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) NMT_C PF02799.10 OAP62262.1 - 4.7e-74 247.8 0.0 7.1e-74 247.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 OAP62262.1 - 8e-69 230.3 0.3 1.4e-68 229.6 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 OAP62262.1 - 3.6e-05 23.6 0.2 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP62262.1 - 0.13 12.0 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein F-box-like PF12937.2 OAP62263.1 - 0.00017 21.2 0.2 0.00017 21.2 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 OAP62263.1 - 0.0011 18.5 0.1 0.0034 17.0 0.0 1.8 2 0 0 2 2 2 1 F-box domain XPG_N PF00752.12 OAP62264.1 - 6.9e-35 119.3 0.0 1.8e-34 118.0 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAP62264.1 - 3.4e-24 84.7 0.0 1.1e-23 83.0 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 OAP62264.1 - 0.00035 20.7 0.0 0.0011 19.1 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 OAP62264.1 - 0.0034 16.8 1.9 0.0034 16.8 1.3 2.9 2 0 0 2 2 2 1 Ubiquitin interaction motif HHH_2 PF12826.2 OAP62264.1 - 0.086 12.7 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif WD40 PF00400.27 OAP62265.1 - 5.6e-33 111.6 2.1 6.3e-08 32.2 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 OAP62265.1 - 6.3e-05 22.7 0.0 0.066 12.9 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 OAP62265.1 - 0.0075 15.9 0.3 1.3 8.7 0.0 3.4 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PSII_BNR PF14870.1 OAP62265.1 - 0.017 14.0 0.1 0.039 12.9 0.0 1.5 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Metallophos PF00149.23 OAP62266.1 - 3.4e-42 144.1 0.6 4.4e-42 143.7 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LSM PF01423.17 OAP62267.1 - 2e-07 30.4 0.0 2.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAP62267.1 - 7e-06 25.8 0.1 1.3e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF4661 PF15576.1 OAP62268.1 - 0.52 9.9 1.7 0.83 9.2 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) N-SET PF11764.3 OAP62269.1 - 3e-36 124.8 0.1 3e-36 124.8 0.0 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 OAP62269.1 - 5.2e-24 85.3 0.1 5.2e-24 85.3 0.1 2.9 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.3 OAP62269.1 - 6.4e-21 73.4 0.3 1.2e-20 72.5 0.2 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 OAP62269.1 - 8.8e-05 22.0 0.0 0.0003 20.3 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trm112p PF03966.11 OAP62270.1 - 5.3e-15 55.5 0.0 9.3e-15 54.7 0.0 1.4 1 1 0 1 1 1 1 Trm112p-like protein A2L_zn_ribbon PF08792.5 OAP62270.1 - 0.1 12.0 0.2 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain Grp1_Fun34_YaaH PF01184.14 OAP62272.1 - 1.1e-86 289.4 17.1 1.4e-86 289.1 11.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Memo PF01875.12 OAP62273.1 - 1.7e-62 210.8 0.0 2.5e-62 210.2 0.0 1.2 1 1 0 1 1 1 1 Memo-like protein Cut8_N PF14482.1 OAP62274.1 - 1.8 8.5 5.1 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Cut8 proteasome-binding domain zf-RING_2 PF13639.1 OAP62275.1 - 0.00044 20.0 7.1 0.0017 18.1 5.5 1.6 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 OAP62275.1 - 0.0068 16.2 2.3 0.011 15.5 1.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 OAP62275.1 - 0.013 15.1 7.9 0.022 14.4 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 OAP62275.1 - 0.048 13.1 0.9 0.13 11.7 0.6 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Tropomyosin_1 PF12718.2 OAP62275.1 - 0.055 13.3 0.8 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 Tropomyosin like zf-rbx1 PF12678.2 OAP62275.1 - 0.15 12.2 5.5 0.29 11.2 3.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAP62275.1 - 0.72 9.5 8.9 1.2 8.8 6.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP62275.1 - 0.98 9.4 7.7 1.7 8.7 5.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 OAP62275.1 - 1.4 8.9 7.2 2.7 8.0 5.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.1 OAP62275.1 - 1.6 8.4 7.7 2.8 7.7 5.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.2 OAP62275.1 - 8.5 6.5 7.9 18 5.5 5.5 1.5 1 0 0 1 1 1 0 RING-variant domain Cyt-b5 PF00173.23 OAP62276.1 - 1.8e-17 62.8 0.0 4.8e-17 61.5 0.0 1.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.23 OAP62277.1 - 6.9e-32 109.3 0.0 8.4e-32 109.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3987 PF13148.1 OAP62278.1 - 0.49 8.9 7.8 0.84 8.1 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Pol_alpha_B_N PF08418.5 OAP62278.1 - 2.8 7.3 7.5 0.2 11.1 2.1 1.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal UvrD_C PF13361.1 OAP62280.1 - 2.9e-74 250.6 0.1 8.4e-74 249.1 0.0 1.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 OAP62280.1 - 2.1e-59 201.3 0.1 9e-58 196.0 0.0 2.8 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 OAP62280.1 - 2.3e-14 53.4 0.0 9e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 OAP62280.1 - 7.6e-14 51.2 0.4 4.2e-13 48.8 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 OAP62280.1 - 7e-07 28.9 0.2 0.022 14.2 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 OAP62280.1 - 2.1e-06 27.4 0.0 0.00046 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 OAP62280.1 - 9e-05 21.9 0.0 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 OAP62280.1 - 0.00067 19.2 0.2 0.0038 16.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain Ras_bdg_2 PF14847.1 OAP62280.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 PsbR PF04725.7 OAP62281.1 - 0.19 11.7 1.2 0.28 11.1 0.6 1.4 1 1 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR Glyco_hydro_16 PF00722.16 OAP62282.1 - 5e-09 35.7 4.6 7.4e-09 35.1 0.3 2.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Polysacc_synt_4 PF04669.8 OAP62282.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis FAD_binding_3 PF01494.14 OAP62283.1 - 1.5e-16 60.4 0.1 2e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP62283.1 - 2.6e-10 39.7 7.0 0.00024 20.1 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP62283.1 - 5.5e-07 29.5 0.7 1.3e-06 28.3 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAP62283.1 - 1.1e-06 28.8 1.3 0.0089 16.4 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP62283.1 - 2.2e-06 27.0 0.3 0.0052 15.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 OAP62283.1 - 1.5e-05 24.3 0.9 2.2e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP62283.1 - 2.5e-05 24.2 2.5 0.00027 20.9 1.8 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP62283.1 - 7.1e-05 22.0 0.4 0.00014 21.0 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 OAP62283.1 - 0.00022 21.3 0.1 0.0007 19.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP62283.1 - 0.00044 18.8 4.2 0.041 12.3 1.9 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 OAP62283.1 - 0.00053 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.17 OAP62283.1 - 0.001 17.9 4.8 0.0028 16.5 3.0 1.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 OAP62283.1 - 0.0011 17.9 5.3 0.0017 17.2 3.2 1.6 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 OAP62283.1 - 0.0018 16.9 6.1 0.14 10.7 2.3 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 OAP62283.1 - 0.0029 16.5 1.6 0.017 14.0 1.1 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.13 OAP62283.1 - 0.041 13.5 1.0 0.085 12.5 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 OAP62283.1 - 0.17 10.6 0.0 0.32 9.7 0.0 1.4 2 0 0 2 2 2 0 Squalene epoxidase F-box-like PF12937.2 OAP62284.1 - 0.00037 20.1 0.6 0.0011 18.6 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP62284.1 - 0.00051 19.6 0.3 0.0014 18.2 0.2 1.8 1 0 0 1 1 1 1 F-box domain DZR PF12773.2 OAP62284.1 - 0.026 14.3 0.6 4.3 7.2 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 OAP62286.1 - 4.2e-08 32.9 3.1 4.2e-08 32.9 2.2 3.1 2 1 0 2 2 2 1 IBR domain zf-C3HC4_4 PF15227.1 OAP62286.1 - 0.014 15.2 19.6 0.014 15.2 13.6 3.6 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAP62286.1 - 0.043 13.5 12.5 0.13 12.0 8.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 OAP62286.1 - 5 7.2 29.9 0.17 11.9 13.5 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cyclin_N PF00134.18 OAP62287.1 - 6.9e-37 125.8 1.3 4.2e-36 123.2 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAP62287.1 - 5.9e-08 32.6 0.0 1.6e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF605 PF04652.11 OAP62288.1 - 4.1 6.7 16.3 6.2 6.1 11.3 1.2 1 0 0 1 1 1 0 Vta1 like PQ-loop PF04193.9 OAP62289.1 - 4.5e-24 83.7 6.5 3.1e-15 55.4 0.8 2.4 2 0 0 2 2 2 2 PQ loop repeat tRNA-synt_2 PF00152.15 OAP62290.1 - 6.1e-101 337.5 0.0 9.3e-101 336.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Aminotran_1_2 PF00155.16 OAP62290.1 - 1.4e-28 99.8 0.0 2.4e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAP62290.1 - 5e-05 22.2 0.0 7.8e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAP62290.1 - 5.7e-05 21.5 0.0 9e-05 20.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 OAP62290.1 - 0.0007 18.8 0.0 0.0022 17.2 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase tRNA-synt_2b PF00587.20 OAP62290.1 - 0.0021 17.6 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 OAP62290.1 - 0.24 10.5 0.0 0.97 8.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ABC2_membrane PF01061.19 OAP62291.1 - 3.4e-33 114.5 21.5 6.1e-33 113.7 14.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAP62291.1 - 1.1e-26 93.7 0.0 1.9e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAP62291.1 - 1.1e-08 35.4 0.0 0.0016 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 OAP62291.1 - 1.6e-06 27.3 25.8 1.6e-06 27.3 17.9 2.4 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 OAP62291.1 - 0.00017 21.0 0.4 0.014 14.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 OAP62291.1 - 0.0006 19.2 0.1 0.0013 18.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAP62291.1 - 0.002 17.3 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 hEGF PF12661.2 OAP62291.1 - 0.0021 18.0 25.9 0.017 15.1 3.5 4.3 4 0 0 4 4 3 2 Human growth factor-like EGF AAA_15 PF13175.1 OAP62291.1 - 0.014 14.4 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 OAP62291.1 - 0.027 14.6 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAP62291.1 - 0.04 14.7 0.0 0.089 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 OAP62291.1 - 0.049 12.8 0.0 0.55 9.4 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAP62291.1 - 0.1 12.9 0.5 0.19 12.0 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAP62291.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 OAP62291.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAP62291.1 - 0.18 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ZZ PF00569.12 OAP62293.1 - 2.7e-06 26.8 8.3 2.7e-06 26.8 5.8 3.0 3 0 0 3 3 3 1 Zinc finger, ZZ type JmjC PF02373.17 OAP62293.1 - 0.00028 21.0 0.0 0.00066 19.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 OAP62293.1 - 0.001 19.1 11.3 0.001 19.1 7.9 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 FlxA PF14282.1 OAP62293.1 - 0.0014 18.5 0.9 0.0025 17.7 0.6 1.4 1 0 0 1 1 1 1 FlxA-like protein Cupin_2 PF07883.6 OAP62293.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin domain AA_permease PF00324.16 OAP62294.1 - 2.1e-109 366.0 42.9 2.5e-109 365.7 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP62294.1 - 4.8e-26 91.2 47.6 5.8e-26 90.9 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 OAP62295.1 - 9.7e-60 202.3 0.0 3e-59 200.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 HEAT PF02985.17 OAP62297.1 - 1.9e-19 67.9 11.2 0.0028 17.6 0.0 11.5 13 0 0 13 13 12 4 HEAT repeat HEAT_2 PF13646.1 OAP62297.1 - 3.3e-19 68.9 12.1 3.9e-06 27.0 0.2 8.7 4 3 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 OAP62297.1 - 2e-16 59.8 12.6 6.9e-05 23.2 0.0 9.6 9 3 3 12 12 12 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAP62297.1 - 1.6e-09 38.0 0.0 0.056 13.8 0.0 5.7 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAP62297.1 - 1.1e-06 28.2 0.0 0.016 14.5 0.0 4.7 4 1 0 4 4 4 2 CLASP N terminal RIX1 PF08167.7 OAP62297.1 - 6.9e-06 25.8 0.0 0.002 17.8 0.0 4.3 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 OAP62297.1 - 7.8e-06 24.8 0.0 0.00016 20.5 0.1 3.1 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal Arm PF00514.18 OAP62297.1 - 1.7e-05 24.4 6.3 0.12 12.2 0.0 5.9 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 OAP62297.1 - 0.00013 21.8 0.4 0.51 10.2 0.0 4.8 5 1 0 5 5 5 1 Exportin 1-like protein Cnd1 PF12717.2 OAP62297.1 - 0.00017 21.4 0.6 0.5 10.1 0.0 4.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 OAP62297.1 - 0.00075 17.9 0.1 0.5 8.6 0.0 3.7 3 1 0 3 3 3 1 Adaptin N terminal region DUF3385 PF11865.3 OAP62297.1 - 0.0033 17.3 0.5 19 5.1 0.0 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Cohesin_HEAT PF12765.2 OAP62297.1 - 0.0066 16.3 0.0 0.95 9.4 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion IBN_N PF03810.14 OAP62297.1 - 0.026 14.4 0.2 0.21 11.5 0.0 2.8 2 0 0 2 2 2 0 Importin-beta N-terminal domain DUF4042 PF13251.1 OAP62297.1 - 0.038 13.4 0.0 18 4.7 0.0 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) DSHCT PF08148.7 OAP62297.1 - 0.049 12.8 0.5 0.18 11.0 0.0 2.3 3 0 0 3 3 3 0 DSHCT (NUC185) domain Bromodomain PF00439.20 OAP62298.1 - 1.3e-21 76.2 0.5 4.8e-21 74.4 0.2 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 OAP62298.1 - 0.00043 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated VanZ PF04892.7 OAP62299.1 - 3.5e-11 43.1 0.4 5e-11 42.6 0.3 1.2 1 0 0 1 1 1 1 VanZ like family DUF2339 PF10101.4 OAP62299.1 - 0.025 12.8 0.2 0.031 12.5 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) NAD_binding_6 PF08030.7 OAP62300.1 - 3.7e-32 111.3 0.0 7.8e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAP62300.1 - 9.9e-22 76.8 0.0 2.4e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 OAP62300.1 - 3.9e-17 62.4 5.4 3.9e-17 62.4 3.7 2.0 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAP62300.1 - 3.7e-05 23.7 0.0 7.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAP62300.1 - 0.1 13.2 0.2 0.48 10.9 0.0 2.3 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain MIS13 PF08202.6 OAP62303.1 - 7.1e-46 156.6 0.1 2.4e-45 154.9 0.0 1.9 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Lzipper-MIP1 PF14389.1 OAP62303.1 - 0.044 13.8 1.6 0.14 12.2 0.9 2.0 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FAD_binding_3 PF01494.14 OAP62304.1 - 1.9e-06 27.1 1.8 0.0074 15.3 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP62304.1 - 0.0006 18.8 2.2 0.13 11.1 0.3 2.6 1 1 0 2 2 2 2 FAD dependent oxidoreductase DUF2411 PF10304.4 OAP62305.1 - 0.083 12.4 0.0 0.33 10.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) YbfN PF13982.1 OAP62306.1 - 0.081 13.1 0.1 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 YbfN-like lipoprotein ADH_zinc_N PF00107.21 OAP62307.1 - 1.6e-26 92.3 0.1 2.6e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP62307.1 - 1.3e-25 89.3 1.0 2.3e-25 88.4 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 OAP62307.1 - 0.00087 18.8 0.0 0.0022 17.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Pyr_redox_3 PF13738.1 OAP62307.1 - 0.042 13.9 0.2 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.1 OAP62307.1 - 0.043 14.7 0.0 0.083 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAP62307.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAP62307.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Apidaecin PF00807.12 OAP62307.1 - 0.12 12.0 1.2 0.24 11.1 0.9 1.4 1 0 0 1 1 1 0 Apidaecin Macoilin PF09726.4 OAP62308.1 - 0.078 11.2 4.8 0.069 11.4 3.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Plasmodium_Vir PF05795.6 OAP62308.1 - 0.12 11.5 0.1 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RAP1 PF07218.6 OAP62308.1 - 0.52 8.3 14.4 0.72 7.8 10.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Orbi_VP6 PF01516.11 OAP62308.1 - 6.6 5.6 9.4 9 5.2 6.5 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 4HBT PF03061.17 OAP62309.1 - 9.6e-09 35.2 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily PBP PF01161.15 OAP62310.1 - 1.9e-16 60.1 0.0 2.4e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MFS_1 PF07690.11 OAP62311.1 - 6.2e-44 150.1 24.9 9e-44 149.6 15.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily p12I PF12233.3 OAP62311.1 - 0.033 14.4 4.9 5.7 7.2 1.7 2.7 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein Cnd2 PF05786.9 OAP62312.1 - 1.2e-182 609.2 9.5 1.7e-182 608.7 6.6 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 EF-hand_4 PF12763.2 OAP62313.1 - 2.8e-24 84.8 0.0 2.3e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 OAP62313.1 - 1e-07 31.3 0.8 2.9e-07 29.8 0.5 1.9 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 OAP62313.1 - 6.6e-05 22.9 0.0 0.0074 16.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 OAP62313.1 - 0.0036 16.4 0.0 0.29 10.5 0.0 2.5 2 0 0 2 2 2 1 EF hand DUF1720 PF08226.6 OAP62313.1 - 0.0045 17.0 31.7 0.0045 17.0 22.0 7.3 4 3 2 6 6 6 2 Domain of unknown function (DUF1720) E3_binding PF02817.12 OAP62313.1 - 0.025 14.2 1.0 0.065 12.8 0.0 2.2 2 0 0 2 2 2 0 e3 binding domain EF-hand_8 PF13833.1 OAP62313.1 - 0.075 12.6 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain pair Fungal_trans PF04082.13 OAP62314.1 - 1.1e-19 70.2 0.1 2.7e-19 69.0 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 OAP62315.1 - 7e-23 81.7 0.0 1.1e-22 81.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP62315.1 - 1.3e-16 59.9 0.0 2.7e-16 58.8 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP62315.1 - 2.5e-10 40.5 0.0 1.1e-06 28.6 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP62315.1 - 3.3e-10 39.8 0.0 1.1e-07 31.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP62315.1 - 2.6e-09 36.4 0.0 1.5e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP62315.1 - 2.9e-06 27.1 1.2 5.6e-05 22.9 0.2 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 OAP62315.1 - 0.00019 21.7 0.0 0.054 13.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP62315.1 - 0.0051 15.7 0.0 1.5 7.6 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAP62315.1 - 0.011 16.0 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 OAP62315.1 - 0.011 15.7 0.1 0.92 9.5 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Thi4 PF01946.12 OAP62315.1 - 0.017 14.2 0.0 0.17 10.9 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 OAP62315.1 - 0.019 15.0 0.0 0.68 10.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 OAP62315.1 - 0.05 12.6 0.0 3 6.7 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.7 OAP62315.1 - 0.079 12.3 0.1 0.73 9.1 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 OAP62315.1 - 0.11 11.6 0.0 0.26 10.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RNA_pol_L_2 PF13656.1 OAP62316.1 - 8.1e-24 82.8 0.1 1.2e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAP62316.1 - 1.1e-12 46.8 0.0 2.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NMO PF03060.10 OAP62317.1 - 2.3e-39 135.4 8.7 1.7e-33 116.2 2.8 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 OAP62317.1 - 5e-10 38.7 2.1 7.4e-10 38.2 1.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 OAP62317.1 - 1.5e-07 30.6 0.1 5.2e-06 25.5 0.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 OAP62317.1 - 4.6e-05 22.4 0.9 7.9e-05 21.7 0.6 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 OAP62317.1 - 0.044 13.0 0.0 0.09 12.0 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein LSM PF01423.17 OAP62318.1 - 2.4e-15 55.7 0.0 2.7e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain Lipase_3 PF01764.20 OAP62319.1 - 1.4e-29 102.5 0.0 2.4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAP62319.1 - 0.0035 17.0 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP62319.1 - 0.007 16.2 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62319.1 - 0.012 15.2 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 OAP62319.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 OAP62319.1 - 0.02 14.2 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 OAP62319.1 - 0.028 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 OAP62319.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.8 OAP62321.1 - 6.5e-71 238.2 0.0 8.2e-71 237.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP62321.1 - 1.4e-09 37.2 0.1 3.3e-09 36.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 OAP62321.1 - 1.9e-07 30.5 0.1 0.00048 19.4 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAP62321.1 - 7.7e-07 29.2 0.1 1.5e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP62321.1 - 5.5e-06 26.2 0.0 9.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 OAP62321.1 - 0.0087 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.13 OAP62321.1 - 0.011 15.0 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 OAP62321.1 - 0.033 13.0 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.7 OAP62321.1 - 0.04 12.3 0.1 0.83 8.0 0.1 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 OAP62321.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold NGP1NT PF08153.7 OAP62322.1 - 3e-48 163.0 0.8 4.8e-48 162.3 0.6 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 OAP62322.1 - 1e-18 67.3 0.0 2e-14 53.5 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP62322.1 - 1.8e-05 24.0 0.0 0.00032 20.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 OAP62322.1 - 0.00028 20.1 0.0 0.08 12.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.18 OAP62322.1 - 0.00051 19.9 0.0 0.3 10.9 0.0 3.5 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 OAP62322.1 - 0.0014 18.0 0.0 0.28 10.6 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 OAP62322.1 - 0.0064 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SusD-like_3 PF14322.1 OAP62322.1 - 0.084 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Metallophos PF00149.23 OAP62323.1 - 1.4e-10 40.8 0.9 2.8e-10 39.9 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP62323.1 - 3e-05 23.9 0.0 0.00013 21.8 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MRP-S26 PF14943.1 OAP62324.1 - 0.26 10.8 7.5 0.71 9.4 5.2 1.7 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 SWI-SNF_Ssr4 PF08549.5 OAP62324.1 - 0.73 8.0 4.3 0.95 7.6 3.0 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Stk19 PF10494.4 OAP62325.1 - 1.6e-60 204.5 0.0 2e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.16 OAP62326.1 - 5.3e-162 539.5 0.2 7.1e-162 539.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 OAP62326.1 - 4.9e-36 123.8 0.0 1e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 OAP62326.1 - 0.0024 17.5 0.0 0.32 10.5 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.6 OAP62326.1 - 0.052 13.0 0.2 0.22 10.9 0.2 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain GFO_IDH_MocA PF01408.17 OAP62327.1 - 5.1e-18 65.7 0.0 8.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Cupin_2 PF07883.6 OAP62329.1 - 1.5e-09 37.2 0.0 2.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain FAD_binding_4 PF01565.18 OAP62330.1 - 1.5e-30 105.4 2.3 2e-30 105.0 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAP62330.1 - 0.0011 18.7 0.1 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like EthD PF07110.6 OAP62331.1 - 1.1e-13 51.9 0.0 1.3e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 EthD domain Abhydrolase_6 PF12697.2 OAP62332.1 - 2.8e-25 89.5 0.4 3.7e-25 89.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62332.1 - 1.4e-10 41.1 0.1 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP62332.1 - 7.5e-06 25.7 0.0 1.5e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP62332.1 - 0.067 13.0 0.2 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF1476 PF07345.6 OAP62332.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1476) Fungal_trans PF04082.13 OAP62333.1 - 3.7e-12 45.6 0.1 6.4e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Kelch_3 PF13415.1 OAP62333.1 - 0.025 14.7 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain NACHT PF05729.7 OAP62334.1 - 3.3e-09 36.6 0.0 1.8e-08 34.1 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 OAP62334.1 - 0.001 18.9 0.3 1.5 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAP62334.1 - 0.0022 18.1 0.0 0.0096 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP62334.1 - 0.009 16.0 0.0 0.009 16.0 0.0 2.9 4 1 0 4 4 4 1 AAA ATPase domain 3H PF02829.9 OAP62334.1 - 0.018 15.0 0.1 0.049 13.6 0.1 1.7 1 0 0 1 1 1 0 3H domain DivIVA PF05103.8 OAP62334.1 - 0.046 13.7 0.2 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 DivIVA protein AAA_18 PF13238.1 OAP62334.1 - 0.074 13.3 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 OAP62334.1 - 0.19 11.1 1.1 0.33 10.3 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 OAP62334.1 - 1.2 9.3 3.6 41 4.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain OTT_1508_deam PF14441.1 OAP62335.1 - 7.2e-13 48.5 0.0 1.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-MYND PF01753.13 OAP62335.1 - 0.039 13.8 10.5 0.086 12.7 7.3 1.6 1 0 0 1 1 1 0 MYND finger adh_short PF00106.20 OAP62336.1 - 4e-10 39.8 2.7 6e-10 39.2 0.6 2.2 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP62336.1 - 1.6e-07 31.3 0.5 3.3e-07 30.3 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DNA_ligase_IV PF11411.3 OAP62336.1 - 0.11 12.2 0.4 0.45 10.3 0.1 2.1 2 0 0 2 2 2 0 DNA ligase IV 4HBT_3 PF13622.1 OAP62337.1 - 5e-50 170.6 0.1 5.8e-50 170.4 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Na_Ca_ex PF01699.19 OAP62338.1 - 5.2e-49 165.4 36.1 5e-25 87.7 9.8 3.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Vpu PF00558.14 OAP62338.1 - 0.081 12.4 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Vpu protein AMP-binding PF00501.23 OAP62339.1 - 1.3e-85 287.2 0.0 1.6e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP62339.1 - 2.9e-11 44.1 0.2 6.2e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Formyl_trans_N PF00551.14 OAP62340.1 - 1.2e-38 132.4 0.0 1.6e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 OAP62340.1 - 0.025 14.2 0.1 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase C2 PF00168.25 OAP62341.1 - 8.8e-09 35.0 0.0 2.2e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 C2 domain AAA PF00004.24 OAP62342.1 - 7.2e-12 45.6 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP62342.1 - 1.7e-10 41.1 0.0 4.6e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAP62342.1 - 1.9e-10 41.0 0.1 2.5e-09 37.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.6 OAP62342.1 - 5.3e-05 22.8 0.2 0.0002 20.9 0.0 2.1 3 0 0 3 3 2 1 CDC6, C terminal AAA_5 PF07728.9 OAP62342.1 - 0.00033 20.4 0.0 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAP62342.1 - 0.002 17.8 0.6 0.11 12.2 0.2 3.1 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 OAP62342.1 - 0.0072 16.0 0.0 0.017 14.8 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 OAP62342.1 - 0.02 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 OAP62342.1 - 0.047 12.6 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Sigma54_activat PF00158.21 OAP62342.1 - 0.062 12.7 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 OAP62342.1 - 0.067 12.5 0.1 0.27 10.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 OAP62342.1 - 0.073 12.7 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 OAP62342.1 - 0.1 11.6 0.0 1.4 7.9 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.17 OAP62342.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 OAP62342.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thioredoxin_7 PF13899.1 OAP62343.1 - 4e-14 52.3 0.0 9e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 OAP62343.1 - 4e-09 36.3 0.0 1.2e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 OAP62343.1 - 1.3e-08 34.1 0.0 3.4e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_2 PF13098.1 OAP62343.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain UIM PF02809.15 OAP62343.1 - 0.025 14.1 3.1 0.081 12.5 2.1 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredox_DsbH PF03190.10 OAP62343.1 - 0.062 13.0 0.1 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pkinase PF00069.20 OAP62344.1 - 2e-71 240.1 0.0 3.1e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP62344.1 - 1.2e-51 175.2 0.0 2.1e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP62344.1 - 6.3e-05 22.0 0.0 0.0088 15.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like ABC1 PF03109.11 OAP62344.1 - 0.025 14.5 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 ABC1 family DUF3074 PF11274.3 OAP62345.1 - 2e-38 131.8 0.0 2.6e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Peptidase_S8 PF00082.17 OAP62346.1 - 7.6e-41 140.1 0.3 1.1e-40 139.5 0.2 1.2 1 0 0 1 1 1 1 Subtilase family p450 PF00067.17 OAP62347.1 - 5.6e-62 209.7 0.0 7.2e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_2 PF03446.10 OAP62348.1 - 6.6e-33 113.8 0.0 8.8e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAP62348.1 - 2.8e-22 79.0 0.0 4.7e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 OAP62348.1 - 0.00092 19.5 0.0 0.0034 17.7 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 OAP62348.1 - 0.0085 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 OAP62348.1 - 0.046 12.4 0.0 0.063 12.0 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family UDPG_MGDP_dh_N PF03721.9 OAP62348.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CMD PF02627.15 OAP62349.1 - 2.8e-22 78.3 0.1 5.2e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Bestrophin PF01062.16 OAP62350.1 - 1.5e-51 175.0 1.1 5.5e-50 169.9 0.8 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Glyco_transf_25 PF01755.12 OAP62351.1 - 5.9e-13 48.9 0.0 1.8e-11 44.0 0.0 2.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Gly_transf_sug PF04488.10 OAP62352.1 - 1.6e-12 47.7 0.0 3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TPPK_C PF12555.3 OAP62352.1 - 0.055 13.1 1.4 0.11 12.2 1.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Abhydrolase_6 PF12697.2 OAP62353.1 - 1.1e-31 110.5 3.1 1.2e-31 110.3 2.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62353.1 - 5.6e-17 62.0 0.1 1.5e-15 57.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP62353.1 - 1.2e-13 51.0 0.4 1.8e-13 50.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP62353.1 - 2.9e-08 33.4 0.0 5.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 OAP62353.1 - 7.1e-05 23.1 0.1 0.00011 22.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.5 OAP62353.1 - 0.0016 18.3 0.0 0.2 11.5 0.1 2.2 2 0 0 2 2 2 1 TAP-like protein DUF2048 PF09752.4 OAP62353.1 - 0.087 11.6 0.2 5.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) AXE1 PF05448.7 OAP62353.1 - 0.096 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1100 PF06500.6 OAP62353.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF3176 PF11374.3 OAP62354.1 - 1.1e-27 96.1 0.9 3e-27 94.6 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MS_channel PF00924.13 OAP62355.1 - 5.9e-15 55.1 0.6 1.3e-14 54.0 0.4 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF4181 PF13789.1 OAP62355.1 - 0.015 15.2 0.5 0.015 15.2 0.3 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4181) 4HBT PF03061.17 OAP62356.1 - 1.3e-08 34.8 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 OAP62356.1 - 4.9e-06 26.9 0.0 6.1e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 OAP62356.1 - 0.00022 20.2 0.1 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase GLTT PF01744.15 OAP62357.1 - 0.055 12.8 0.3 0.096 12.1 0.2 1.4 1 0 0 1 1 1 0 GLTT repeat (6 copies) MARVEL PF01284.18 OAP62357.1 - 0.055 13.2 1.6 0.06 13.1 0.6 1.6 1 1 0 1 1 1 0 Membrane-associating domain PIP5K PF01504.13 OAP62359.1 - 8.1e-60 202.0 0.3 1.7e-59 201.0 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 OAP62359.1 - 3.1e-28 98.6 0.0 5.2e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 OAP62359.1 - 1.7e-14 53.4 8.9 4.1e-14 52.2 6.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger DZR PF12773.2 OAP62359.1 - 1.9 8.3 8.5 0.26 11.1 2.3 2.2 3 0 0 3 3 3 0 Double zinc ribbon F-box PF00646.28 OAP62360.1 - 0.0019 17.7 2.3 0.0025 17.4 0.1 2.2 2 0 0 2 2 2 1 F-box domain FAD_binding_3 PF01494.14 OAP62361.1 - 1.4e-17 63.7 0.0 3.4e-17 62.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 OAP62361.1 - 5.9e-05 23.4 0.0 0.00039 20.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP62361.1 - 0.00016 20.6 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 OAP62361.1 - 0.00068 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 OAP62361.1 - 0.00071 19.5 0.1 0.0053 16.6 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP62361.1 - 0.00077 19.4 0.2 0.0022 17.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP62361.1 - 0.0023 16.8 0.3 0.0045 15.9 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAP62361.1 - 0.0025 16.4 1.0 0.81 8.2 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.9 OAP62361.1 - 0.003 16.0 0.1 0.005 15.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 OAP62361.1 - 0.0058 15.7 2.4 0.082 11.9 1.8 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 OAP62361.1 - 0.023 14.2 0.0 0.023 14.2 0.0 2.2 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 OAP62361.1 - 0.051 13.2 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP62361.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 OAP62362.1 - 7.5e-20 71.6 0.5 1.2e-19 71.0 0.3 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP62362.1 - 7.8e-14 51.4 0.0 1.8e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 OAP62362.1 - 2.4e-08 34.2 0.6 7.1e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 OAP62362.1 - 0.00021 21.1 0.3 0.00073 19.4 0.1 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 OAP62362.1 - 0.021 14.8 0.7 0.051 13.5 0.4 1.6 1 1 1 2 2 2 0 NADH(P)-binding CoA_binding PF02629.14 OAP62362.1 - 0.068 13.6 1.2 0.084 13.3 0.1 1.7 2 0 0 2 2 2 0 CoA binding domain Amidohydro_2 PF04909.9 OAP62363.1 - 6.2e-32 111.2 0.7 1.1e-31 110.4 0.5 1.4 1 1 0 1 1 1 1 Amidohydrolase PS_Dcarbxylase PF02666.10 OAP62364.1 - 2.7e-52 177.0 0.0 4.6e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 OAP62364.1 - 5.4e-32 109.4 0.0 1e-16 60.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain Ring_hydroxyl_A PF00848.14 OAP62364.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) YL1 PF05764.8 OAP62364.1 - 7.2 6.1 13.0 0.27 10.8 4.3 1.9 2 0 0 2 2 2 0 YL1 nuclear protein HhH-GPD PF00730.20 OAP62365.1 - 2.7e-07 30.8 0.0 4.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DPBB_1 PF03330.13 OAP62366.1 - 4e-06 26.7 0.0 5.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAP62366.1 - 0.093 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Barwin family Amidase PF01425.16 OAP62367.1 - 2.2e-75 254.1 0.5 2.6e-74 250.6 0.4 2.1 1 1 0 1 1 1 1 Amidase Fasciclin PF02469.17 OAP62368.1 - 1.6e-45 154.2 3.2 2.5e-27 95.3 0.7 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF1777 PF08648.7 OAP62369.1 - 8.1e-07 28.9 31.0 8.1e-07 28.9 21.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 OAP62370.1 - 0.005 15.3 3.5 0.0051 15.3 2.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF4611 PF15387.1 OAP62370.1 - 0.0097 16.0 2.2 0.015 15.4 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Vfa1 PF08432.5 OAP62370.1 - 0.13 12.3 1.7 0.18 11.7 1.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TAF4 PF05236.9 OAP62370.1 - 0.19 10.9 4.9 0.24 10.6 3.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CDC45 PF02724.9 OAP62370.1 - 0.21 9.5 4.2 0.26 9.2 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3245 PF11595.3 OAP62370.1 - 0.32 11.2 6.2 0.48 10.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Paf1 PF03985.8 OAP62370.1 - 0.39 9.3 7.3 0.46 9.1 5.0 1.1 1 0 0 1 1 1 0 Paf1 Rad50_zn_hook PF04423.9 OAP62370.1 - 0.55 9.7 2.5 0.47 9.9 0.2 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Trypan_PARP PF05887.6 OAP62370.1 - 4.9 6.9 8.4 2 8.2 0.9 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Acetyltransf_1 PF00583.19 OAP62371.1 - 4.5e-14 52.2 0.0 8.6e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 OAP62371.1 - 6.8e-07 28.9 0.1 1.2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 OAP62371.1 - 0.00053 20.1 0.0 0.0008 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP62371.1 - 0.0061 16.4 0.2 0.0096 15.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAP62371.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 OAP62371.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase adh_short PF00106.20 OAP62372.1 - 7.7e-27 94.2 0.0 1.3e-26 93.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP62372.1 - 6.4e-23 81.7 0.0 1.1e-20 74.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP62372.1 - 8.4e-11 41.8 0.0 1.7e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 OAP62372.1 - 0.0029 16.8 0.0 0.0041 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 OAP62372.1 - 0.0068 15.8 0.1 0.058 12.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HEAT PF02985.17 OAP62373.1 - 7.8e-10 37.9 2.2 0.094 12.8 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat Pkinase PF00069.20 OAP62373.1 - 4.8e-09 35.7 0.0 8.3e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP62373.1 - 1.1e-05 24.5 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 OAP62373.1 - 0.00013 22.1 0.1 0.04 14.1 0.0 3.4 1 1 2 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 OAP62373.1 - 0.0024 18.2 0.1 0.18 12.3 0.0 3.3 2 1 1 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 OAP62373.1 - 0.18 11.6 0.0 1.6 8.5 0.0 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 OAP62373.1 - 0.21 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1857 PF08982.6 OAP62375.1 - 5.7e-36 123.3 0.0 6.4e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Zn_clus PF00172.13 OAP62376.1 - 1.5e-05 24.7 10.5 1.5e-05 24.7 7.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP62376.1 - 0.0012 17.5 0.2 0.012 14.2 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain SUR7 PF06687.7 OAP62377.1 - 5.7e-40 137.1 9.9 7e-40 136.8 6.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family YwiC PF14256.1 OAP62377.1 - 3.4 7.7 11.4 0.14 12.2 3.3 2.0 3 0 0 3 3 3 0 YwiC-like protein TPR_12 PF13424.1 OAP62379.1 - 7.8e-35 118.6 3.8 1.6e-14 53.5 0.0 5.1 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAP62379.1 - 4.4e-27 93.1 3.0 2.4e-08 33.6 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat NACHT PF05729.7 OAP62379.1 - 5.5e-12 45.6 0.0 1.7e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.1 OAP62379.1 - 8.2e-10 37.7 3.8 0.035 13.8 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAP62379.1 - 1.6e-08 34.0 0.0 0.00014 21.4 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 OAP62379.1 - 4.8e-07 29.2 1.5 0.33 10.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.1 OAP62379.1 - 4.8e-07 29.9 0.0 4.8e-07 29.9 0.0 3.5 3 1 1 4 4 4 1 AAA ATPase domain TPR_1 PF00515.23 OAP62379.1 - 1.6e-06 27.4 0.1 0.21 11.2 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 OAP62379.1 - 5.3e-06 26.5 0.0 3.3e-05 24.0 0.0 2.4 2 1 0 2 2 1 1 AAA domain TPR_8 PF13181.1 OAP62379.1 - 1.4e-05 24.5 0.0 1.3 9.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_19 PF13245.1 OAP62379.1 - 0.00037 20.1 0.0 0.0014 18.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain TPR_16 PF13432.1 OAP62379.1 - 0.00087 19.9 1.3 0.11 13.1 0.0 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat AAA_14 PF13173.1 OAP62379.1 - 0.0016 18.3 0.0 0.028 14.3 0.0 2.9 1 1 0 1 1 1 1 AAA domain TPR_14 PF13428.1 OAP62379.1 - 0.0021 18.5 1.2 1.6 9.5 0.0 4.5 3 1 1 4 4 3 1 Tetratricopeptide repeat NB-ARC PF00931.17 OAP62379.1 - 0.003 16.4 0.0 0.0062 15.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 OAP62379.1 - 0.0062 16.6 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 OAP62379.1 - 0.01 15.4 0.0 0.038 13.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 OAP62379.1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 OAP62379.1 - 0.033 15.0 0.1 0.23 12.2 0.0 2.6 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 OAP62379.1 - 0.038 13.4 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 OAP62379.1 - 0.052 12.9 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 OAP62379.1 - 0.055 13.7 0.4 0.5 10.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter MobB PF03205.9 OAP62379.1 - 0.068 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 OAP62379.1 - 0.11 11.9 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 OAP62379.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4551 PF15087.1 OAP62380.1 - 1.6 6.9 4.9 1.4 7.2 2.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4551) vWA-TerF-like PF10138.4 OAP62381.1 - 6e-06 26.2 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 OAP62381.1 - 3.5e-05 23.5 0.0 6.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 OAP62381.1 - 0.00015 21.9 0.0 0.00068 19.7 0.0 2.1 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 OAP62381.1 - 0.0098 15.0 0.0 0.024 13.7 0.0 1.6 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein UPF0270 PF06794.7 OAP62381.1 - 0.15 11.7 0.1 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Ank_2 PF12796.2 OAP62382.1 - 6.1e-45 151.4 0.1 5.7e-16 58.6 0.0 4.6 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 OAP62382.1 - 5.5e-44 145.8 4.5 1.3e-10 40.5 0.0 7.6 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 OAP62382.1 - 5.7e-34 115.8 5.4 3.5e-09 36.9 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP62382.1 - 5.7e-32 106.5 0.8 6e-05 22.9 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 OAP62382.1 - 1.2e-23 82.5 8.8 5.1e-07 29.7 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) DUF676 PF05057.9 OAP62382.1 - 0.00054 19.3 0.0 0.00079 18.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 OAP62382.1 - 0.00069 19.5 0.1 0.0026 17.6 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP62382.1 - 0.0027 17.4 0.0 0.043 13.5 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP62382.1 - 0.0027 17.3 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 OAP62382.1 - 0.0097 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 OAP62382.1 - 0.095 12.0 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) MmgE_PrpD PF03972.9 OAP62383.1 - 1.7e-38 131.9 6.9 1.7e-38 131.9 4.8 1.5 1 1 1 2 2 2 1 MmgE/PrpD family AA_permease PF00324.16 OAP62384.1 - 6.6e-88 295.1 45.6 1.4e-87 294.0 31.6 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP62384.1 - 5.4e-25 87.8 47.8 7.3e-25 87.3 33.1 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 OAP62385.1 - 8.6e-05 22.4 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 OAP62385.1 - 0.0054 16.4 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAP62385.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TauD PF02668.11 OAP62386.1 - 1.9e-36 126.0 0.1 2.4e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ECH PF00378.15 OAP62387.1 - 1.4e-36 125.8 0.1 2.1e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family BACON PF13004.2 OAP62387.1 - 0.085 13.0 0.4 0.16 12.2 0.3 1.3 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal His_Phos_2 PF00328.17 OAP62388.1 - 2.3e-23 83.0 0.0 2.9e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) p450 PF00067.17 OAP62390.1 - 3.6e-69 233.4 0.0 4.5e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 OAP62391.1 - 4.6e-24 85.2 1.1 7.7e-24 84.4 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62391.1 - 1.5e-15 57.2 2.2 7.9e-15 54.9 0.5 2.0 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAP62391.1 - 7e-06 25.9 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAP62391.1 - 3.3e-05 23.5 0.3 0.00031 20.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP62391.1 - 0.0022 17.4 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP62391.1 - 0.026 13.4 0.1 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 OAP62392.1 - 2e-15 56.7 0.0 2.7e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 OAP62392.1 - 1e-05 24.7 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Aldo_ket_red PF00248.16 OAP62393.1 - 6.7e-49 166.2 0.0 7.9e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SLX9 PF15341.1 OAP62394.1 - 2.1e-33 115.2 4.0 3e-33 114.8 2.7 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 EthD PF07110.6 OAP62395.1 - 0.00031 21.6 0.0 0.0011 19.8 0.0 1.7 1 1 0 1 1 1 1 EthD domain DUF1445 PF07286.7 OAP62396.1 - 3.7e-55 185.5 0.0 5e-55 185.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Cellulase PF00150.13 OAP62397.1 - 1.3e-28 99.9 1.0 2.2e-28 99.2 0.7 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Myelin_MBP PF01669.12 OAP62397.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Myelin basic protein Sugar_tr PF00083.19 OAP62398.1 - 2.8e-74 250.3 14.4 3.5e-74 250.0 10.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62398.1 - 6.1e-27 94.2 20.3 2.2e-26 92.4 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP62398.1 - 5.1e-07 28.2 2.2 1.1e-06 27.1 1.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 OAP62398.1 - 3.2e-06 25.8 12.6 0.00013 20.4 2.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF2235 PF09994.4 OAP62399.1 - 7.5e-32 110.8 0.0 1.3e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TauD PF02668.11 OAP62400.1 - 1e-49 169.5 0.0 1.3e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.20 OAP62401.1 - 6.1e-29 100.9 0.0 1.3e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP62401.1 - 3.7e-09 36.0 0.1 2.9e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 OAP62401.1 - 0.047 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family PBP PF01161.15 OAP62402.1 - 2.3e-19 69.7 0.0 3.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.13 OAP62403.1 - 9.8e-08 31.7 10.9 1.9e-07 30.8 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caprin-1_C PF12287.3 OAP62403.1 - 0.22 10.8 1.2 0.39 10.0 0.8 1.4 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Fungal_trans_2 PF11951.3 OAP62404.1 - 8.3e-11 41.0 0.3 1.8e-10 40.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fer2_2 PF01799.15 OAP62404.1 - 0.038 13.9 0.2 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 [2Fe-2S] binding domain WD40 PF00400.27 OAP62405.1 - 1.5e-10 40.5 9.2 0.076 12.9 0.1 8.9 10 1 0 10 10 10 3 WD domain, G-beta repeat DUF1335 PF07056.6 OAP62405.1 - 0.0036 17.0 0.1 0.57 9.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1335) Rad4 PF03835.10 OAP62406.1 - 1.8e-15 56.6 7.4 3.1e-15 55.8 5.1 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 OAP62406.1 - 1.6e-13 50.8 1.4 3.7e-13 49.6 1.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ogr_Delta PF04606.7 OAP62406.1 - 2.2 8.0 5.5 0.4 10.3 0.7 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger AA_permease PF00324.16 OAP62407.1 - 2.8e-121 405.1 43.3 2.2e-109 365.9 17.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 OAP62407.1 - 1e-26 93.4 38.7 3.3e-26 91.8 18.3 2.1 1 1 1 2 2 2 2 Amino acid permease MBOAT_2 PF13813.1 OAP62410.1 - 2.7e-18 65.8 0.7 1e-17 63.9 0.5 2.1 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family peroxidase PF00141.18 OAP62411.1 - 4.6e-52 176.7 0.0 7.9e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase AIF-MLS PF14962.1 OAP62411.1 - 0.028 14.0 1.2 0.046 13.3 0.8 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence MFS_1 PF07690.11 OAP62413.1 - 1.4e-37 129.2 27.7 2.1e-37 128.6 19.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.23 OAP62414.1 - 2.8e-84 283.7 0.2 3.9e-84 283.2 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP62414.1 - 2e-08 34.1 0.9 1.2e-07 31.4 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP62414.1 - 0.0023 17.1 0.1 0.0043 16.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AMP-binding PF00501.23 OAP62415.1 - 1.6e-68 231.0 0.0 2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP62415.1 - 7.2e-14 52.4 0.0 1.9e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PI-PLC-X PF00388.14 OAP62416.1 - 3.2e-48 162.8 0.0 4.9e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 OAP62416.1 - 2.1e-32 111.5 0.2 4.8e-32 110.4 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain BolA PF01722.13 OAP62417.1 - 1.7e-27 95.1 0.1 2.1e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein SNARE PF05739.14 OAP62418.1 - 4.3e-13 48.7 10.4 7.8e-12 44.7 4.0 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 OAP62418.1 - 1.2e-07 31.8 5.8 3.4e-07 30.3 0.1 2.3 2 0 0 2 2 2 1 Syntaxin HHH_2 PF12826.2 OAP62418.1 - 0.0048 16.7 0.4 0.02 14.7 0.2 2.0 1 1 1 2 2 2 1 Helix-hairpin-helix motif Rifin_STEVOR PF02009.11 OAP62418.1 - 0.0052 16.4 2.7 0.0052 16.4 1.9 1.9 2 1 1 3 3 3 1 Rifin/stevor family PTA_PTB PF01515.14 OAP62418.1 - 0.023 13.7 2.3 0.033 13.2 1.6 1.2 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase DUF1634 PF07843.6 OAP62418.1 - 0.03 13.9 0.7 0.056 13.0 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1634) Syntaxin_2 PF14523.1 OAP62418.1 - 0.14 12.2 5.8 0.17 11.9 0.4 2.9 2 1 0 2 2 2 0 Syntaxin-like protein Tweety PF04906.8 OAP62418.1 - 0.26 9.6 4.3 0.073 11.4 1.1 1.5 2 0 0 2 2 2 0 Tweety DUF4094 PF13334.1 OAP62418.1 - 0.37 11.2 4.3 0.73 10.2 0.6 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) MCPsignal PF00015.16 OAP62418.1 - 0.47 9.9 12.3 0.12 11.9 4.8 2.4 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Minor_capsid_3 PF12691.2 OAP62418.1 - 0.92 9.1 3.7 2 8.1 0.1 2.3 2 1 0 2 2 2 0 Minor capsid protein from bacteriophage TBPIP PF07106.8 OAP62418.1 - 1.2 8.6 7.2 6.9 6.1 1.2 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HisKA_3 PF07730.8 OAP62418.1 - 5.3 7.4 9.2 9.1 6.7 0.6 3.6 3 1 1 4 4 4 0 Histidine kinase Spectrin PF00435.16 OAP62418.1 - 6.1 7.1 11.7 3 8.1 1.0 3.5 2 2 1 3 3 3 0 Spectrin repeat NAPRTase PF04095.11 OAP62419.1 - 1.7e-55 187.9 0.0 2.7e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family ADH_N PF08240.7 OAP62420.1 - 9e-13 47.9 0.8 5.2e-11 42.2 0.1 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP62420.1 - 8.9e-09 34.9 0.3 1.4e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 OAP62420.1 - 0.11 12.2 0.6 0.28 11.0 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_16 PF00722.16 OAP62421.1 - 4.5e-41 140.1 3.7 7.4e-41 139.4 2.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Protocadherin PF08374.6 OAP62421.1 - 0.00092 18.9 0.1 0.0015 18.2 0.1 1.2 1 0 0 1 1 1 1 Protocadherin Mid2 PF04478.7 OAP62421.1 - 0.0021 17.5 0.1 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 OAP62421.1 - 0.0083 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Shisa PF13908.1 OAP62421.1 - 0.026 14.7 0.2 0.045 13.9 0.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1191 PF06697.7 OAP62421.1 - 0.041 12.6 0.1 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 OAP62421.1 - 0.059 11.6 0.0 0.086 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Peptidase_M56 PF05569.6 OAP62421.1 - 0.064 12.2 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 CD34_antigen PF06365.7 OAP62421.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Synaptobrevin PF00957.16 OAP62421.1 - 0.12 12.0 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Synaptobrevin Cation_efflux PF01545.16 OAP62425.1 - 2.6e-35 121.9 9.4 3.3e-35 121.5 6.5 1.1 1 0 0 1 1 1 1 Cation efflux family Sugar_tr PF00083.19 OAP62426.1 - 6.3e-43 146.9 2.6 7.3e-43 146.7 1.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62426.1 - 2.4e-08 33.0 5.2 2.8e-08 32.8 3.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 OAP62427.1 - 3.1e-23 82.5 0.0 5.6e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP62427.1 - 5.9e-05 22.8 0.0 0.00031 20.5 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Pkinase PF00069.20 OAP62428.1 - 6.9e-41 140.1 0.0 2.7e-40 138.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP62428.1 - 6.2e-27 94.2 0.0 9.4e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP62428.1 - 0.0015 17.5 0.0 0.0031 16.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 OAP62428.1 - 0.033 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP62428.1 - 0.089 12.5 1.9 0.18 11.5 0.1 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family LHC PF00556.15 OAP62428.1 - 0.32 10.8 5.1 0.88 9.4 1.8 2.4 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit ANTH PF07651.11 OAP62429.1 - 5.2e-61 205.8 0.1 7e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 OAP62429.1 - 4.4e-06 26.5 0.0 7.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 ENTH domain PPP1R35_C PF15503.1 OAP62429.1 - 1.2 8.6 6.3 1.5 8.3 0.2 2.6 1 1 1 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus TPP_enzyme_N PF02776.13 OAP62430.1 - 6.8e-33 113.5 0.4 1.1e-32 112.9 0.3 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAP62430.1 - 2.6e-16 59.5 0.1 2.9e-15 56.1 0.0 2.6 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP62430.1 - 6.1e-16 58.4 0.0 5.5e-15 55.3 0.0 2.3 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Filament PF00038.16 OAP62432.1 - 0.03 13.8 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF3819 PF12842.2 OAP62433.1 - 0.087 12.5 0.4 0.13 11.9 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3819) HsbA PF12296.3 OAP62433.1 - 3.4 7.5 13.7 5.3 6.9 1.1 2.1 1 1 1 2 2 2 0 Hydrophobic surface binding protein A HSP20 PF00011.16 OAP62437.1 - 3.9e-18 65.1 0.8 1.2e-11 44.3 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Abhydrolase_6 PF12697.2 OAP62438.1 - 3.2e-39 135.1 0.1 3.6e-39 134.9 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62438.1 - 7e-29 101.0 0.0 8.5e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP62438.1 - 7.6e-27 93.8 0.3 3.2e-17 62.6 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP62438.1 - 1.2e-12 47.4 0.1 2.7e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 OAP62438.1 - 2.3e-08 33.5 0.0 0.0064 15.7 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 OAP62438.1 - 5.3e-05 22.7 0.0 0.00065 19.2 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 OAP62438.1 - 0.0003 20.6 0.0 0.0021 17.9 0.0 2.3 3 0 0 3 3 3 1 TAP-like protein MTD PF01993.13 OAP62438.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Peptidase_S15 PF02129.13 OAP62438.1 - 0.0016 17.9 0.1 0.26 10.6 0.0 2.3 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Ser_hydrolase PF06821.8 OAP62438.1 - 0.002 17.7 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.9 OAP62438.1 - 0.0031 16.0 0.0 0.021 13.3 0.0 1.9 2 0 0 2 2 2 1 Ndr family FSH1 PF03959.8 OAP62438.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 OAP62438.1 - 0.025 13.8 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.7 OAP62438.1 - 0.033 12.6 0.3 0.13 10.7 0.1 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 OAP62438.1 - 0.036 13.7 0.1 0.13 11.9 0.1 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 OAP62438.1 - 0.036 13.7 0.0 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.8 OAP62438.1 - 0.047 11.9 0.1 8.4 4.5 0.0 2.7 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II DUF915 PF06028.6 OAP62438.1 - 0.082 11.9 0.1 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 OAP62438.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein LIP PF03583.9 OAP62438.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase GST_N_3 PF13417.1 OAP62440.1 - 9.5e-19 67.4 0.1 1.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP62440.1 - 1.1e-14 54.1 0.0 2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP62440.1 - 8.6e-10 38.6 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 OAP62440.1 - 0.00022 21.1 0.0 0.00051 19.9 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 OAP62440.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WW PF00397.21 OAP62441.1 - 5e-09 35.8 0.6 1.4e-08 34.4 0.4 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 OAP62441.1 - 0.051 12.1 0.1 0.11 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoD-like phosphatase Fungal_trans_2 PF11951.3 OAP62442.1 - 2.1e-12 46.3 0.0 3.3e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ISG65-75 PF11727.3 OAP62443.1 - 0.087 11.8 2.2 0.11 11.4 1.5 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF883 PF05957.8 OAP62443.1 - 2.2 8.7 7.6 9.1 6.7 2.5 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1929 PF09118.6 OAP62444.1 - 0.17 11.9 6.0 0.44 10.6 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) MFS_1 PF07690.11 OAP62448.1 - 3.4e-08 32.6 55.9 3.4e-08 32.6 38.7 3.6 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1769 PF08588.5 OAP62449.1 - 1.9e-29 101.3 0.1 4.8e-29 100.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Ycf1 PF05758.7 OAP62449.1 - 0.0025 15.6 0.0 0.0025 15.6 0.0 1.1 1 0 0 1 1 1 1 Ycf1 DUF3086 PF11285.3 OAP62449.1 - 0.043 12.6 1.0 0.063 12.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF874 PF05917.6 OAP62449.1 - 2.7 6.7 9.3 3.7 6.3 6.5 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) YqfQ PF14181.1 OAP62449.1 - 6.7 6.7 6.1 10 6.1 4.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein YwqJ-deaminase PF14431.1 OAP62450.1 - 0.05 13.4 0.7 0.17 11.7 0.5 1.9 1 0 0 1 1 1 0 YwqJ-like deaminase Tropomyosin PF00261.15 OAP62450.1 - 6.3 5.8 56.2 0.99 8.4 0.0 5.0 3 1 1 4 4 4 0 Tropomyosin Filament PF00038.16 OAP62450.1 - 7 6.0 50.0 1.3 8.4 7.8 3.7 2 1 2 4 4 4 0 Intermediate filament protein DUF3584 PF12128.3 OAP62450.1 - 9.4 3.4 48.8 0.51 7.6 11.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) RhoGAP PF00620.22 OAP62451.1 - 1.5e-14 53.9 0.0 1.5e-14 53.9 0.0 2.1 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.18 OAP62451.1 - 1.1e-12 47.9 0.0 4.8e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 OAP62451.1 - 1.9e-10 40.3 0.0 4e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Sipho_Gp157 PF05565.6 OAP62451.1 - 0.13 11.8 1.0 5 6.6 0.0 2.5 2 0 0 2 2 2 0 Siphovirus Gp157 PK PF00224.16 OAP62452.1 - 8.5e-169 560.6 4.8 1.1e-168 560.3 3.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 OAP62452.1 - 1.3e-30 105.3 0.0 3.5e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 OAP62452.1 - 5.2e-05 22.2 0.7 0.00014 20.8 0.4 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 OAP62452.1 - 0.00085 18.3 0.0 0.017 13.9 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF3506 PF12014.3 OAP62453.1 - 8.8e-47 158.3 0.0 2.5e-45 153.5 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 OAP62453.1 - 6.2e-10 38.6 3.6 1.3e-09 37.6 2.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP62453.1 - 1.3e-08 34.2 3.2 1.3e-08 34.2 2.2 1.7 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.6 OAP62453.1 - 0.0039 17.5 0.0 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Antimicrobial10 PF08105.6 OAP62454.1 - 0.057 13.0 0.5 8.2 6.1 0.0 2.9 2 0 0 2 2 2 0 Metchnikowin family Epimerase PF01370.16 OAP62456.1 - 1.1e-07 31.5 0.0 2.4e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP62456.1 - 0.0048 16.9 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAP62456.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 OAP62456.1 - 0.036 13.9 0.1 0.071 13.0 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 OAP62456.1 - 0.088 11.6 0.1 0.17 10.7 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain Glyco_hydro_42 PF02449.10 OAP62457.1 - 0.019 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Macoilin PF09726.4 OAP62457.1 - 1.8 6.7 9.3 2.5 6.2 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein CCDC155 PF14662.1 OAP62458.1 - 0.0096 15.5 4.4 0.016 14.7 3.0 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 APG6 PF04111.7 OAP62458.1 - 0.23 10.4 5.3 0.37 9.8 3.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Iso_dh PF00180.15 OAP62459.1 - 9.6e-98 327.3 0.0 1.3e-96 323.5 0.0 1.9 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Na_trans_assoc PF06512.8 OAP62459.1 - 0.092 12.6 0.2 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated ATP-synt_S1 PF05827.7 OAP62460.1 - 2.7e-43 148.3 0.1 3.4e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) ThiF PF00899.16 OAP62461.1 - 1.6e-37 128.3 0.2 2.8e-37 127.5 0.2 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 OAP62461.1 - 1.2e-21 76.0 1.2 2.6e-18 65.3 0.2 2.3 2 0 0 2 2 2 2 MoeZ/MoeB domain Rhodanese PF00581.15 OAP62461.1 - 0.00038 20.7 0.0 0.13 12.5 0.0 2.7 2 0 0 2 2 2 2 Rhodanese-like domain NAD_binding_7 PF13241.1 OAP62461.1 - 0.12 12.6 0.0 0.57 10.4 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 OAP62462.1 - 5.9e-46 156.0 0.0 5.6e-45 152.8 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 OAP62462.1 - 1.4e-45 154.6 0.0 2.2e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Slp PF03843.8 OAP62462.1 - 0.016 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family Pox_VLTF3 PF04947.9 OAP62462.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Metallophos PF00149.23 OAP62463.1 - 8.7e-13 48.1 0.1 2.1e-12 46.8 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP62463.1 - 1.9e-10 40.7 0.0 4.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acyl-CoA_dh_1 PF00441.19 OAP62465.1 - 4.5e-36 124.2 1.6 7.3e-36 123.5 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP62465.1 - 1.3e-15 56.6 0.7 2.7e-15 55.6 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 OAP62465.1 - 2e-15 56.3 0.0 4e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 OAP62465.1 - 4.1e-09 37.0 0.0 1.1e-08 35.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAP62465.1 - 4e-06 27.1 0.1 7.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_VLP PF14194.1 OAP62465.1 - 0.081 12.6 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich VLP NMO PF03060.10 OAP62466.1 - 5.6e-60 203.2 0.9 7.8e-60 202.7 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAP62466.1 - 3.2e-08 32.8 0.0 0.0013 17.6 0.0 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAP62466.1 - 0.034 12.9 0.7 0.056 12.2 0.5 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Nitro_FeMo-Co PF02579.12 OAP62466.1 - 0.088 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor adh_short PF00106.20 OAP62467.1 - 2.5e-21 76.2 0.1 3.3e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP62467.1 - 2.2e-08 34.1 0.0 2.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAP62467.1 - 4.7e-05 23.4 0.0 8.6e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAP62467.1 - 0.00072 19.2 0.3 0.0014 18.2 0.1 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAP62467.1 - 0.0018 17.9 0.2 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAP62467.1 - 0.032 14.6 0.2 0.066 13.6 0.1 1.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 OAP62467.1 - 0.065 13.3 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 OAP62467.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AMP-binding PF00501.23 OAP62468.1 - 1.1e-92 310.6 0.0 1.3e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP62468.1 - 2.9e-12 47.3 0.1 9.2e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DSBA PF01323.15 OAP62469.1 - 4e-16 59.1 0.0 4.6e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Peptidase_M19 PF01244.16 OAP62470.1 - 2.5e-88 296.1 0.0 3e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Cellulase PF00150.13 OAP62471.1 - 1.7e-27 96.3 0.1 2e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_trans_2_3 PF13632.1 OAP62472.1 - 1.1e-17 64.4 0.8 1.1e-17 64.4 0.5 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAP62472.1 - 1.6e-06 28.1 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 hDGE_amylase PF14701.1 OAP62475.1 - 5.3e-170 565.8 0.0 7.4e-170 565.4 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 OAP62475.1 - 2.6e-114 381.7 0.0 4.8e-114 380.9 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DAHP_synth_1 PF00793.15 OAP62475.1 - 3.8e-99 330.8 0.0 9.2e-98 326.2 0.0 2.1 2 0 0 2 2 2 1 DAHP synthetase I family hGDE_central PF14702.1 OAP62475.1 - 1.7e-83 279.7 0.0 2.6e-83 279.2 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 OAP62475.1 - 1.2e-26 92.3 0.0 2.3e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 OAP62475.1 - 7e-05 22.3 0.0 0.0051 16.2 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF3602 PF12223.3 OAP62476.1 - 5e-16 58.8 14.5 9.7e-14 51.5 2.9 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Vasculin PF15337.1 OAP62476.1 - 0.076 13.4 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Velvet PF11754.3 OAP62477.1 - 3.5e-59 199.8 0.0 5.8e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Sec10 PF07393.6 OAP62478.1 - 7.6e-127 424.3 0.7 1.1e-126 423.7 0.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 OAP62478.1 - 5.1e-06 26.0 0.2 1.1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP62478.1 - 3.4e-05 23.4 0.1 9.8e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like CAP PF00188.21 OAP62480.1 - 1.9e-17 63.8 6.1 2.8e-17 63.3 4.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NAD_binding_10 PF13460.1 OAP62481.1 - 0.028 14.4 0.2 0.93 9.4 0.1 2.3 1 1 0 1 1 1 0 NADH(P)-binding FMN_dh PF01070.13 OAP62482.1 - 8.4e-107 357.0 0.0 1.1e-106 356.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAP62482.1 - 1.8e-18 66.0 0.0 3.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAP62482.1 - 0.00035 19.6 0.0 0.00057 18.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAP62482.1 - 0.0014 17.5 0.7 0.014 14.2 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 OAP62482.1 - 0.0061 15.7 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase RabGAP-TBC PF00566.13 OAP62483.1 - 1.3e-22 80.3 0.0 2e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PGBA_C PF15437.1 OAP62483.1 - 6.9 6.8 13.3 2.2 8.4 0.3 2.6 3 0 0 3 3 3 0 Plasminogen-binding protein pgbA C-terminal Telomerase_RBD PF12009.3 OAP62484.1 - 2.1e-40 137.7 0.3 5.2e-40 136.5 0.0 1.8 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 OAP62484.1 - 9.3e-13 48.0 0.0 8.2e-12 44.9 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NHL PF01436.16 OAP62484.1 - 0.024 14.5 0.4 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 NHL repeat RhoGEF PF00621.15 OAP62485.1 - 7.7e-36 123.6 0.1 1.6e-35 122.5 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 OAP62485.1 - 6.1e-10 38.9 4.4 6.1e-10 38.9 3.0 2.2 2 0 0 2 2 2 1 BAR domain Peptidase_C48 PF02902.14 OAP62486.1 - 5.2e-16 58.9 0.7 1.7e-15 57.2 0.5 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MFS_1 PF07690.11 OAP62487.1 - 1.3e-21 76.7 20.5 1.6e-21 76.4 14.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 OAP62488.1 - 1.7e-06 27.0 0.0 2.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4407 PF14362.1 OAP62489.1 - 0.45 9.4 8.6 0.75 8.6 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4_3 PF13920.1 OAP62490.1 - 1.6e-05 24.4 9.4 1.6e-05 24.4 6.5 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.3 OAP62490.1 - 0.14 11.8 1.2 0.3 10.8 0.9 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain SWIB PF02201.13 OAP62491.1 - 6.5e-24 83.4 0.1 1.1e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 OAP62491.1 - 2.4e-12 46.4 0.4 4.6e-12 45.5 0.3 1.5 1 0 0 1 1 1 1 DEK C terminal domain SRP-alpha_N PF04086.8 OAP62491.1 - 1.4 8.2 11.8 2 7.7 8.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal eIF2A PF08662.6 OAP62492.1 - 4.9e-40 137.3 6.1 8.6e-36 123.4 1.3 4.1 3 3 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 OAP62492.1 - 6.2e-07 28.9 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP62492.1 - 6.8e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP62492.1 - 8.6e-06 25.6 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 OAP62492.1 - 0.077 12.9 0.7 44 4.1 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat Metal_resist PF13801.1 OAP62492.1 - 0.72 9.8 3.0 0.44 10.5 0.5 1.8 2 0 0 2 2 2 0 Heavy-metal resistance Cep57_MT_bd PF06657.8 OAP62493.1 - 0.0057 16.5 3.7 0.008 16.0 0.1 2.5 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Ribosomal_L5_C PF00673.16 OAP62495.1 - 3.1e-23 81.3 0.0 4.4e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 OAP62495.1 - 5.5e-21 74.1 0.0 1.7e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 OAP62496.1 - 3.9e-19 67.9 0.0 6.7e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 LSM domain Nop25 PF09805.4 OAP62497.1 - 1.1e-37 129.1 11.2 1.1e-37 129.1 7.7 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) DUF4504 PF14953.1 OAP62497.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) Tropomyosin_1 PF12718.2 OAP62498.1 - 3.6e-50 169.5 37.2 4.7e-50 169.1 25.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 OAP62498.1 - 2.7e-09 36.4 35.8 0.00024 20.2 13.0 2.6 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 OAP62498.1 - 0.00091 19.2 12.5 0.00091 19.2 8.7 2.6 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Spc7 PF08317.6 OAP62498.1 - 0.0013 17.4 18.4 0.0013 17.4 12.7 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein Herpes_pp85 PF04637.7 OAP62498.1 - 0.0027 16.0 1.9 0.0027 16.0 1.3 1.4 1 1 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4200 PF13863.1 OAP62498.1 - 0.0074 16.2 36.2 0.091 12.7 10.5 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Mod_r PF07200.8 OAP62498.1 - 0.013 15.4 30.7 0.1 12.5 13.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 PF01576.14 OAP62498.1 - 0.016 13.0 35.4 0.018 12.7 24.6 1.0 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 OAP62498.1 - 0.049 13.2 35.0 1.3 8.6 8.7 2.2 1 1 1 2 2 2 0 IncA protein ERM PF00769.14 OAP62498.1 - 0.056 12.9 40.9 0.075 12.5 13.3 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family APG6 PF04111.7 OAP62498.1 - 0.057 12.4 37.8 0.31 10.0 13.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 OAP62498.1 - 0.094 12.8 26.9 0.44 10.7 1.2 3.2 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 OAP62498.1 - 0.11 12.4 36.8 2.4 8.0 25.7 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 OAP62498.1 - 0.11 10.3 21.1 0.13 10.1 14.4 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 OAP62498.1 - 0.11 12.3 33.3 1.1 9.0 8.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 OAP62498.1 - 0.14 12.0 22.3 1.1 9.1 1.2 4.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 OAP62498.1 - 0.14 9.4 34.0 0.76 7.0 23.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Transketolase_N PF00456.16 OAP62498.1 - 0.14 10.9 9.4 0.19 10.5 6.5 1.0 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Filament PF00038.16 OAP62498.1 - 0.15 11.5 30.9 3.3 7.1 21.4 2.0 1 1 0 1 1 1 0 Intermediate filament protein EzrA PF06160.7 OAP62498.1 - 0.15 10.2 27.0 0.012 13.8 4.3 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA GAS PF13851.1 OAP62498.1 - 0.15 11.2 35.4 0.5 9.5 24.5 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 OAP62498.1 - 0.19 11.5 42.3 2.3 8.0 11.5 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.7 OAP62498.1 - 0.2 10.0 9.4 0.24 9.7 6.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 OAP62498.1 - 0.24 10.5 5.6 19 4.3 3.2 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Lebercilin PF15619.1 OAP62498.1 - 0.27 10.6 36.8 1.1 8.6 11.3 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KAR9 PF08580.5 OAP62498.1 - 0.29 9.3 13.2 0.038 12.2 0.7 2.0 1 1 1 2 2 2 0 Yeast cortical protein KAR9 PilJ PF13675.1 OAP62498.1 - 0.31 11.3 19.1 0.25 11.6 2.4 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ADIP PF11559.3 OAP62498.1 - 0.31 10.9 37.0 0.44 10.4 8.9 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Tektin PF03148.9 OAP62498.1 - 0.36 9.3 25.1 1.5 7.2 17.4 1.9 1 1 0 1 1 1 0 Tektin family Striatin PF08232.7 OAP62498.1 - 0.4 10.9 29.7 0.91 9.8 12.8 2.2 1 1 1 2 2 2 0 Striatin family Laminin_II PF06009.7 OAP62498.1 - 0.49 10.1 21.9 0.075 12.7 5.7 2.3 1 1 1 2 2 2 0 Laminin Domain II WXG100 PF06013.7 OAP62498.1 - 0.49 10.4 20.5 0.23 11.5 0.4 3.8 2 1 0 2 2 1 0 Proteins of 100 residues with WXG AAA_13 PF13166.1 OAP62498.1 - 0.55 8.6 27.9 2.2 6.6 7.5 1.7 1 1 0 1 1 1 0 AAA domain DUF4140 PF13600.1 OAP62498.1 - 0.58 10.6 26.1 0.22 12.0 4.2 3.0 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.5 OAP62498.1 - 0.58 10.2 22.0 2.5 8.2 8.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 OAP62498.1 - 1 9.6 14.3 4 7.7 0.1 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein BTAD PF03704.12 OAP62498.1 - 1.1 9.5 16.4 0.087 13.1 1.1 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain DUF724 PF05266.9 OAP62498.1 - 1.1 8.7 31.4 0.53 9.8 8.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IFT46_B_C PF12317.3 OAP62498.1 - 1.2 8.4 10.3 0.15 11.4 3.3 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF904 PF06005.7 OAP62498.1 - 1.5 9.2 39.8 1.1 9.6 5.5 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF904) DUF972 PF06156.8 OAP62498.1 - 1.8 8.9 28.7 1.5e+04 -6.4 20.1 3.2 1 1 0 1 1 0 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 OAP62498.1 - 2 6.7 25.9 0.51 8.6 6.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Vac_Fusion PF02346.11 OAP62498.1 - 2.1 7.8 7.7 6 6.3 0.2 3.3 3 1 0 3 3 3 0 Chordopoxvirus fusion protein Seryl_tRNA_N PF02403.17 OAP62498.1 - 2.2 8.3 34.1 3.4 7.7 1.0 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 OAP62498.1 - 2.3 7.0 30.5 0.23 10.3 15.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 OAP62498.1 - 2.4 7.8 31.5 5.4 6.7 14.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding EHN PF06441.7 OAP62498.1 - 2.5 8.0 13.4 0.55 10.1 3.7 2.6 1 1 2 3 3 3 0 Epoxide hydrolase N terminus DUF2458 PF10454.4 OAP62498.1 - 2.5 7.9 24.0 1.2 8.9 9.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) DUF4201 PF13870.1 OAP62498.1 - 3 7.2 30.5 11 5.3 9.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Nup54 PF13874.1 OAP62498.1 - 3 7.4 26.0 0.79 9.3 8.4 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF725 PF05267.7 OAP62498.1 - 3 7.7 7.0 20 5.1 2.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF725) Spectrin PF00435.16 OAP62498.1 - 3.1 8.1 30.5 4 7.7 13.0 2.4 1 1 1 2 2 2 0 Spectrin repeat HAP1_N PF04849.8 OAP62498.1 - 3.8 6.3 32.4 2.6e+02 0.3 22.4 3.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF948 PF06103.6 OAP62498.1 - 4.2 7.3 15.1 5 7.0 1.5 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Peptidase_S64 PF08192.6 OAP62498.1 - 4.8 5.3 14.8 5.6 5.1 10.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1664 PF07889.7 OAP62498.1 - 5 6.9 16.8 1 9.1 2.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 OAP62498.1 - 5.4 7.5 21.5 1.4 9.3 3.9 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fes1 PF08609.5 OAP62498.1 - 5.6 7.5 9.7 0.88 10.1 1.0 2.7 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 TPR_MLP1_2 PF07926.7 OAP62498.1 - 6.2 6.5 40.5 5.5 6.7 8.6 2.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3138 PF11336.3 OAP62498.1 - 6.4 4.8 5.6 8.8 4.3 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AAA_27 PF13514.1 OAP62498.1 - 7.1 4.1 34.3 1.3e+02 -0.0 23.6 2.2 1 1 0 1 1 1 0 AAA domain MAD PF05557.8 OAP62498.1 - 7.5 4.5 35.7 10 4.0 24.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein PRESAN PF09687.5 OAP62498.1 - 7.6 6.6 9.7 8.3 6.4 0.5 2.5 1 1 0 2 2 2 0 Plasmodium RESA N-terminal DUF342 PF03961.8 OAP62498.1 - 8.6 4.6 28.3 0.64 8.3 8.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF465 PF04325.8 OAP62498.1 - 8.7 6.1 15.2 13 5.6 0.1 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF465) Ax_dynein_light PF10211.4 OAP62498.1 - 9.9 5.9 31.7 10 5.9 4.7 2.9 1 1 1 2 2 2 0 Axonemal dynein light chain Aminotran_4 PF01063.14 OAP62500.1 - 1.3e-22 80.4 0.0 1.6e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Evr1_Alr PF04777.8 OAP62501.1 - 4.3e-25 87.4 0.4 1.8e-24 85.4 0.1 2.0 1 1 1 2 2 2 1 Erv1 / Alr family Toxin-deaminase PF14424.1 OAP62501.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Methyltransf_2 PF00891.13 OAP62502.1 - 1.4e-30 106.2 0.0 2.1e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 OAP62502.1 - 3.3e-07 30.8 0.0 1.5e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAP62502.1 - 6.4e-05 22.3 0.0 0.00022 20.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 OAP62502.1 - 0.00028 20.4 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP62502.1 - 0.00028 21.2 0.0 0.00083 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP62502.1 - 0.0004 20.7 0.0 0.0016 18.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP62502.1 - 0.00073 19.5 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 OAP62502.1 - 0.00075 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 OAP62502.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 OAP62502.1 - 0.033 14.6 0.1 0.24 11.9 0.0 2.5 3 0 0 3 3 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 OAP62502.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.16 OAP62503.1 - 3.9e-68 229.3 0.1 4.5e-68 229.1 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family COG6 PF06419.6 OAP62503.1 - 0.071 11.2 0.1 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DEAD PF00270.24 OAP62504.1 - 2e-46 157.5 0.0 3.6e-45 153.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP62504.1 - 2.8e-27 94.3 0.1 6e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP62504.1 - 0.008 16.0 0.0 0.018 14.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S28e PF01200.13 OAP62504.1 - 0.057 13.1 0.1 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S28e CMS1 PF14617.1 OAP62504.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 OAP62504.1 - 0.31 9.4 0.0 0.7 8.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) Pro_isomerase PF00160.16 OAP62505.1 - 1.6e-46 158.3 0.4 1.9e-46 158.0 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 OAP62506.1 - 1e-21 77.3 0.2 1.5e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Arena_nucleocap PF00843.12 OAP62506.1 - 0.081 10.7 0.1 0.1 10.4 0.1 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein AA_permease PF00324.16 OAP62507.1 - 8.2e-56 189.3 32.3 1.1e-55 188.9 22.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 OAP62508.1 - 1.7e-82 277.1 30.7 2e-82 276.8 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein tRNA-synt_1g PF09334.6 OAP62509.1 - 1e-105 353.5 0.4 2.8e-105 352.1 0.3 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAP62509.1 - 7.4e-18 63.8 2.7 3.3e-09 35.3 0.0 3.3 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 OAP62509.1 - 2.6e-10 39.9 0.0 2.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain SAP PF02037.22 OAP62510.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 SAP domain Ish1 PF10281.4 OAP62510.1 - 0.066 13.2 0.2 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein HATPase_c PF02518.21 OAP62511.1 - 6.2e-19 67.7 0.0 1.1e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP62511.1 - 4.9e-17 61.9 0.2 1.5e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 OAP62511.1 - 2.8e-07 30.4 0.1 6.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AMP-binding PF00501.23 OAP62512.1 - 2.4e-72 243.6 0.0 3.2e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP62512.1 - 5.2e-09 36.9 0.2 1.3e-08 35.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 OAP62512.1 - 0.15 10.5 0.1 0.79 8.1 0.0 1.9 2 0 0 2 2 2 0 GH3 auxin-responsive promoter G_glu_transpept PF01019.16 OAP62513.1 - 1.4e-157 525.2 0.6 1.7e-157 525.0 0.4 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.11 OAP62514.1 - 2.3e-49 167.9 34.3 2.3e-49 167.9 23.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP62514.1 - 1.1e-09 37.3 11.2 1.1e-09 37.3 7.8 2.8 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAP62514.1 - 6.4e-05 21.3 1.7 0.00011 20.5 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_2 PF02230.11 OAP62515.1 - 7.5e-37 126.8 0.0 2.4e-36 125.2 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 OAP62515.1 - 6.1e-10 39.0 0.0 9.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP62515.1 - 8.3e-07 29.1 0.0 0.0002 21.3 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 OAP62515.1 - 5.4e-06 26.0 0.0 8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.17 OAP62515.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_3 PF07859.8 OAP62515.1 - 0.0085 15.6 0.0 0.022 14.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP62515.1 - 0.022 13.9 0.1 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.7 OAP62515.1 - 0.022 13.2 0.1 0.052 12.0 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) RNB PF00773.14 OAP62516.1 - 1.8e-95 319.9 0.1 2.5e-95 319.4 0.1 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 OAP62516.1 - 2.3e-11 43.9 0.1 6.9e-11 42.3 0.1 1.8 1 0 0 1 1 1 1 PIN domain Methyltransf_4 PF02390.12 OAP62517.1 - 3e-49 166.7 0.0 4e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAP62517.1 - 0.00031 21.2 0.0 0.00047 20.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP62517.1 - 0.0041 17.1 0.0 0.0083 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP62517.1 - 0.019 15.2 0.0 0.055 13.8 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 OAP62517.1 - 0.073 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) AA_permease_2 PF13520.1 OAP62518.1 - 1e-53 182.4 52.6 1.3e-53 182.1 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP62518.1 - 1.9e-21 75.9 42.9 2.5e-21 75.5 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease PDR_CDR PF06422.7 OAP62518.1 - 0.7 9.5 3.2 0.56 9.8 0.1 2.5 2 0 0 2 2 2 0 CDR ABC transporter Cation_efflux PF01545.16 OAP62520.1 - 1.1e-29 103.3 3.7 1.6e-29 102.8 2.6 1.1 1 0 0 1 1 1 1 Cation efflux family zf-RING_2 PF13639.1 OAP62521.1 - 7.4e-09 35.3 7.1 7.4e-09 35.3 4.9 1.7 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 OAP62521.1 - 2.9e-06 27.0 1.5 2.9e-06 27.0 1.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 OAP62521.1 - 4.2e-05 23.0 6.6 9.4e-05 21.9 4.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 OAP62521.1 - 5.2e-05 23.2 4.2 5.2e-05 23.2 2.9 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAP62521.1 - 8.3e-05 22.1 4.5 8.3e-05 22.1 3.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP62521.1 - 0.00011 22.1 7.6 0.00024 21.0 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP62521.1 - 0.00049 19.7 7.0 0.001 18.7 4.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAP62521.1 - 0.0012 18.4 2.7 0.0028 17.3 1.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 OAP62521.1 - 0.0014 18.5 7.9 0.0014 18.5 5.5 1.8 2 1 0 2 2 2 1 FANCL C-terminal domain Usp PF00582.21 OAP62521.1 - 0.0078 16.4 0.0 0.023 14.8 0.0 1.7 2 0 0 2 2 2 1 Universal stress protein family zf-C3HC4_4 PF15227.1 OAP62521.1 - 0.0099 15.7 7.1 0.059 13.2 4.9 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-PHD-like PF15446.1 OAP62521.1 - 0.08 12.2 3.6 1.5 8.0 0.9 2.5 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Rad50_zn_hook PF04423.9 OAP62521.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C3HC4 PF00097.20 OAP62521.1 - 0.58 9.8 13.4 0.038 13.6 5.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RasGEF PF00617.14 OAP62522.1 - 2.7e-52 177.2 0.6 5.6e-52 176.2 0.2 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 OAP62522.1 - 2.7e-15 56.3 0.0 1.2e-14 54.2 0.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 OAP62522.1 - 7.7e-08 31.8 0.0 1.9e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAP62522.1 - 4e-06 26.1 0.0 9.3e-06 24.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Hexapep PF00132.19 OAP62523.1 - 1.4e-11 43.3 8.2 2.4e-06 26.7 1.3 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAP62523.1 - 1.4e-07 30.9 4.2 0.00066 19.1 0.4 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 OAP62523.1 - 1.9e-07 30.8 9.9 1.9e-07 30.8 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.3 OAP62523.1 - 0.027 14.4 0.2 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase MutL_C PF08676.6 OAP62524.1 - 1e-11 44.6 0.1 9.5e-11 41.4 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 OAP62524.1 - 4.1e-11 42.6 0.0 8.5e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAP62524.1 - 0.00069 19.3 0.0 0.0019 17.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med5 PF08689.5 OAP62525.1 - 2.7e-56 190.9 0.0 5.2e-53 180.0 0.1 2.5 1 1 1 2 2 2 2 Mediator complex subunit Med5 Zn_clus PF00172.13 OAP62526.1 - 0.011 15.6 3.4 0.022 14.6 2.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.22 OAP62527.1 - 2.1e-07 30.8 0.2 6.4e-06 25.9 0.1 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP62527.1 - 0.0034 16.9 0.0 0.012 15.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans_2 PF11951.3 OAP62529.1 - 0.00015 20.5 1.5 0.0075 14.9 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 OAP62530.1 - 1.9e-13 50.8 0.3 3.6e-13 49.9 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP62530.1 - 2.4e-08 33.8 0.1 1.4e-07 31.3 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62530.1 - 0.0017 17.9 0.0 0.028 13.9 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold LIP PF03583.9 OAP62530.1 - 0.0023 17.2 0.3 0.011 14.9 0.0 2.1 3 0 0 3 3 3 1 Secretory lipase DUF1100 PF06500.6 OAP62530.1 - 0.015 13.8 0.0 0.032 12.8 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 OAP62530.1 - 0.02 14.1 0.2 0.57 9.3 0.0 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.6 OAP62530.1 - 0.13 11.9 0.0 0.7 9.5 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal ABC_tran PF00005.22 OAP62533.1 - 2.6e-38 131.4 0.0 1e-17 64.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAP62533.1 - 1e-13 51.9 1.9 1.5e-05 25.1 0.0 4.1 2 2 0 4 4 4 3 AAA domain ABC_membrane PF00664.18 OAP62533.1 - 2.2e-12 46.9 21.9 4.2e-07 29.6 2.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.1 OAP62533.1 - 2.6e-08 33.2 0.1 0.0016 17.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 OAP62533.1 - 4.9e-08 33.1 1.0 0.0011 18.9 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 OAP62533.1 - 1.2e-07 31.9 0.0 0.033 14.3 0.0 3.4 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 OAP62533.1 - 1.9e-07 30.2 0.2 0.048 12.5 0.0 3.4 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_25 PF13481.1 OAP62533.1 - 4.7e-06 26.1 0.0 0.029 13.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 OAP62533.1 - 4.9e-06 26.2 1.2 0.24 10.8 0.0 3.3 2 1 0 3 3 3 2 AAA-like domain SMC_N PF02463.14 OAP62533.1 - 8.4e-06 25.1 0.4 4.4 6.4 0.0 4.2 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 OAP62533.1 - 2.3e-05 24.2 0.0 0.0077 15.9 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_23 PF13476.1 OAP62533.1 - 2.3e-05 24.8 0.0 0.012 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAP62533.1 - 3.3e-05 23.1 0.7 0.0079 15.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAP62533.1 - 5.9e-05 23.8 0.0 0.22 12.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 OAP62533.1 - 0.0001 22.5 0.3 2 8.6 0.0 4.2 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 OAP62533.1 - 0.00016 22.1 0.1 0.59 10.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 OAP62533.1 - 0.00049 19.6 0.0 0.74 9.2 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_24 PF13479.1 OAP62533.1 - 0.00082 19.0 0.1 0.72 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 OAP62533.1 - 0.00094 19.1 1.7 0.4 10.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase KaiC PF06745.8 OAP62533.1 - 0.001 18.2 0.0 7.9 5.5 0.0 3.6 3 0 0 3 3 3 0 KaiC MobB PF03205.9 OAP62533.1 - 0.0012 18.6 0.2 0.26 10.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 OAP62533.1 - 0.003 17.4 0.0 4.4 7.1 0.0 3.2 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 OAP62533.1 - 0.0036 16.0 0.4 0.23 10.1 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit DUF87 PF01935.12 OAP62533.1 - 0.0038 17.0 2.0 0.022 14.5 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_14 PF13173.1 OAP62533.1 - 0.0038 17.1 0.3 0.19 11.6 0.0 3.7 5 0 0 5 5 5 1 AAA domain RNA_helicase PF00910.17 OAP62533.1 - 0.0045 17.1 0.2 1.8 8.7 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.1 OAP62533.1 - 0.0069 16.6 0.0 12 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 OAP62533.1 - 0.0091 15.5 0.1 1.7 8.0 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 OAP62533.1 - 0.011 15.3 0.1 5 6.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain GTP_EFTU PF00009.22 OAP62533.1 - 0.074 12.4 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF815 PF05673.8 OAP62533.1 - 0.074 11.9 0.1 3.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 OAP62533.1 - 0.083 12.3 1.3 4.5 6.7 0.1 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 OAP62533.1 - 0.092 11.9 0.7 1.2 8.3 0.0 2.9 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 OAP62533.1 - 0.098 12.3 0.9 8 6.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.10 OAP62533.1 - 0.1 11.2 0.1 1.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AIG1 PF04548.11 OAP62533.1 - 0.16 11.0 0.8 2.8 7.0 0.1 2.6 3 0 0 3 3 3 0 AIG1 family Septin PF00735.13 OAP62533.1 - 0.18 10.8 0.0 7 5.5 0.0 2.2 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.18 OAP62533.1 - 0.24 11.1 4.1 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family p450 PF00067.17 OAP62534.1 - 1.9e-58 198.1 0.0 2.7e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DLH PF01738.13 OAP62535.1 - 6.6e-20 71.3 0.0 7.9e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAP62535.1 - 4.3e-06 26.5 0.0 6.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1275 PF06912.6 OAP62536.1 - 3.3e-37 127.7 14.4 4.1e-37 127.4 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Acyl_transf_3 PF01757.17 OAP62536.1 - 0.42 9.3 16.6 0.019 13.8 3.5 2.1 1 1 0 2 2 2 0 Acyltransferase family 7TMR-DISM_7TM PF07695.6 OAP62536.1 - 2.2 7.8 11.7 12 5.4 8.2 2.1 1 1 0 1 1 1 0 7TM diverse intracellular signalling Cupin_1 PF00190.17 OAP62537.1 - 7.3e-30 103.3 0.0 1.3e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 OAP62537.1 - 1.4e-24 85.3 1.2 1.6e-12 46.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 OAP62537.1 - 8.5e-11 41.0 0.0 0.0002 20.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 OAP62537.1 - 4.8e-08 32.7 0.3 0.00031 20.4 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 OAP62537.1 - 0.00025 20.7 0.0 0.26 10.8 0.0 2.2 2 0 0 2 2 2 2 Cupin FdtA PF05523.6 OAP62537.1 - 0.0031 16.9 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 WxcM-like, C-terminal ARD PF03079.9 OAP62537.1 - 0.0072 16.2 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 1 ARD/ARD' family CENP-C_C PF11699.3 OAP62537.1 - 0.011 15.6 0.0 4.1 7.4 0.0 3.0 3 0 0 3 3 3 0 Mif2/CENP-C like MannoseP_isomer PF01050.13 OAP62537.1 - 0.02 14.5 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase Fungal_trans PF04082.13 OAP62538.1 - 4.1e-16 58.6 0.0 6.5e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP62538.1 - 2.9e-08 33.4 9.7 5.2e-08 32.6 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP62539.1 - 1.9e-19 69.5 0.0 3.4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_mRNA-cap PF03341.8 OAP62539.1 - 0.025 13.6 0.7 0.041 12.9 0.2 1.5 2 0 0 2 2 2 0 Poxvirus mRNA capping enzyme, small subunit Sugar_tr PF00083.19 OAP62540.1 - 2.3e-37 128.6 12.4 3.2e-37 128.1 8.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62540.1 - 1.1e-10 40.7 11.6 1.5e-10 40.3 8.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF791 PF05631.9 OAP62540.1 - 1.3e-05 24.0 1.0 1.5e-05 23.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_2 PF13347.1 OAP62540.1 - 0.028 12.8 5.8 0.044 12.1 4.0 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein Sugar_tr PF00083.19 OAP62541.1 - 4.1e-40 137.7 4.0 4.6e-40 137.5 2.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Cytochrom_B_C PF00032.12 OAP62541.1 - 0.062 13.5 2.3 0.078 13.2 0.9 1.6 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD ADH_zinc_N PF00107.21 OAP62542.1 - 1.6e-27 95.6 0.5 2.4e-27 95.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III PF08545.5 OAP62542.1 - 0.014 15.0 0.5 0.029 14.0 0.3 1.6 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GCV_H PF01597.14 OAP62544.1 - 1.5e-42 144.0 1.5 2e-42 143.7 1.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 OAP62544.1 - 0.043 13.4 0.3 0.12 12.0 0.2 1.8 1 0 0 1 1 1 0 Biotin-requiring enzyme RnfC_N PF13375.1 OAP62544.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Ribosomal_S6 PF01250.12 OAP62545.1 - 1.7e-10 40.5 0.0 2.4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Dynamin_N PF00350.18 OAP62546.1 - 1.3e-42 145.4 0.0 2.4e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 OAP62546.1 - 5.7e-12 45.0 0.0 1.7e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 OAP62546.1 - 0.00061 19.7 0.0 0.0021 18.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAP62546.1 - 0.0033 17.9 0.0 0.0082 16.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 OAP62546.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.1 OAP62547.1 - 2e-16 59.4 0.0 1.4e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAP62547.1 - 8.6e-10 38.6 0.0 4.4e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAP62547.1 - 1.3e-06 27.4 0.0 3.7e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 Glutamine amidotransferases class-II ketoacyl-synt PF00109.21 OAP62549.1 - 3.2e-23 82.4 2.0 8.1e-23 81.1 1.1 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 OAP62549.1 - 5.6e-15 55.2 0.0 2.4e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.1 OAP62549.1 - 4.4e-13 49.5 0.0 8.7e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP62549.1 - 2.8e-05 24.0 0.0 0.00053 19.9 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase ACP_syn_III PF08545.5 OAP62549.1 - 0.13 11.9 0.9 4.4 7.0 0.0 3.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cys_Met_Meta_PP PF01053.15 OAP62550.1 - 1.7e-115 385.4 0.0 1.9e-115 385.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 OAP62550.1 - 1.7e-09 36.9 0.3 3.1e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 OAP62550.1 - 3e-08 33.1 0.4 4.5e-08 32.5 0.3 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 OAP62550.1 - 4.9e-08 32.3 0.0 7.5e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.11 OAP62550.1 - 0.00067 18.4 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 OAP62550.1 - 0.0038 16.4 0.0 0.0086 15.2 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 OAP62550.1 - 0.033 12.5 0.0 0.05 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Abhydrolase_1 PF00561.15 OAP62551.1 - 3.8e-16 59.3 0.1 2.1e-15 56.9 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP62551.1 - 8e-14 52.0 0.0 1.4e-13 51.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 OAP62551.1 - 0.00019 20.0 0.0 0.00033 19.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family Cys_Met_Meta_PP PF01053.15 OAP62552.1 - 5e-118 393.7 0.0 5.7e-118 393.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAP62552.1 - 2.1e-11 43.4 0.0 8.1e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 OAP62552.1 - 1.6e-07 30.7 0.1 2.7e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 OAP62552.1 - 1.3e-06 27.4 0.5 2.8e-06 26.3 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V GDC-P PF02347.11 OAP62552.1 - 0.0036 16.0 0.0 0.0052 15.5 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 OAP62552.1 - 0.031 13.3 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Met_gamma_lyase PF06838.6 OAP62552.1 - 0.085 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase ThiG PF05690.9 OAP62552.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG NAS PF03059.11 OAP62553.1 - 7.3e-28 97.5 0.0 8.7e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_25 PF13649.1 OAP62553.1 - 0.0074 16.6 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP62553.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAP62553.1 - 0.04 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 OAP62554.1 - 4.7e-15 55.6 0.0 7.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP62554.1 - 8.9e-08 32.6 0.0 1.8e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 OAP62555.1 - 1.2e-21 76.7 24.2 1.2e-21 76.7 16.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily BIV_Env PF05858.7 OAP62555.1 - 0.13 10.1 0.3 0.61 7.9 0.0 2.0 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) Abhydrolase_1 PF00561.15 OAP62556.1 - 2.8e-35 121.9 0.1 9.3e-34 116.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP62556.1 - 1.1e-15 58.1 0.1 3.8e-15 56.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP62556.1 - 8.6e-05 22.3 0.1 0.00081 19.1 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAP62556.1 - 0.00012 21.5 0.4 0.0002 20.9 0.3 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 OAP62556.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2048 PF09752.4 OAP62556.1 - 0.061 12.1 0.0 7.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Thioesterase PF00975.15 OAP62556.1 - 0.12 12.6 0.1 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain ABC_tran PF00005.22 OAP62557.1 - 7.8e-38 129.8 0.0 7.5e-18 65.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 OAP62557.1 - 3.9e-29 101.9 30.9 4.8e-18 65.5 10.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 OAP62557.1 - 1.6e-07 31.6 0.0 0.096 12.6 0.0 4.2 3 1 0 4 4 4 1 AAA domain SMC_N PF02463.14 OAP62557.1 - 2.1e-07 30.4 0.9 0.23 10.6 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAP62557.1 - 4.3e-07 29.3 2.0 0.0078 15.7 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 OAP62557.1 - 1.5e-06 28.9 0.0 0.0039 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAP62557.1 - 5.6e-06 26.4 0.1 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP62557.1 - 6.6e-06 26.2 0.1 0.2 11.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAP62557.1 - 3.6e-05 23.2 0.5 0.02 14.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 OAP62557.1 - 6.4e-05 23.2 0.3 0.045 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAP62557.1 - 0.00016 21.2 0.0 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 OAP62557.1 - 0.00028 20.5 0.1 0.06 13.0 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 OAP62557.1 - 0.00032 19.9 0.1 0.068 12.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 OAP62557.1 - 0.00038 20.3 0.7 0.021 14.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 OAP62557.1 - 0.00047 19.1 0.0 0.035 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 OAP62557.1 - 0.0005 20.4 0.3 0.52 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 OAP62557.1 - 0.00065 19.6 0.1 1.4 8.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 OAP62557.1 - 0.0012 18.3 0.9 0.14 11.5 0.1 2.9 3 0 0 3 3 3 1 AAA-like domain Dynamin_N PF00350.18 OAP62557.1 - 0.0015 18.3 0.1 0.061 13.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 OAP62557.1 - 0.002 18.0 0.2 0.063 13.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 OAP62557.1 - 0.0049 17.3 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 OAP62557.1 - 0.011 15.3 0.1 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 OAP62557.1 - 0.012 15.0 0.2 0.057 12.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 OAP62557.1 - 0.019 15.1 0.1 5.4 7.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 OAP62557.1 - 0.045 13.6 0.1 0.38 10.7 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 OAP62557.1 - 0.046 13.9 1.0 0.57 10.3 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 OAP62557.1 - 0.1 12.2 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 OAP62557.1 - 0.16 11.0 0.1 9.5 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATP-grasp_4 PF13535.1 OAP62559.1 - 2.2e-25 89.4 0.2 9.6e-24 84.1 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAP62559.1 - 2.1e-13 49.7 0.0 1.8e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAP62559.1 - 3.7e-06 26.4 0.0 9.1e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 OAP62559.1 - 0.0032 17.3 0.0 0.043 13.6 0.0 2.4 3 0 0 3 3 3 1 ATP-grasp domain GARS_A PF01071.14 OAP62559.1 - 0.0096 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 OAP62559.1 - 0.02 14.1 0.0 0.05 12.8 0.0 1.7 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF1635 PF07795.6 OAP62560.1 - 0.61 9.4 6.1 0.092 12.1 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) ATP-grasp_4 PF13535.1 OAP62561.1 - 9.5e-23 80.8 0.0 6.2e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAP62561.1 - 3e-07 30.0 0.0 3.5e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 OAP62561.1 - 0.00011 21.1 0.0 0.00022 20.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 OAP62561.1 - 0.0011 18.3 0.0 0.019 14.2 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GSH-S_ATP PF02955.11 OAP62561.1 - 0.0065 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.9 OAP62561.1 - 0.05 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain 4HBT_2 PF13279.1 OAP62562.1 - 1.1e-07 32.3 0.0 1.5e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Ank PF00023.25 OAP62563.1 - 1.6e-13 49.6 0.3 2.9e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 OAP62563.1 - 3.1e-12 46.6 0.0 4.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP62563.1 - 1.7e-09 37.6 0.1 7.5e-06 26.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP62563.1 - 4e-09 35.8 0.0 3.1e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 OAP62563.1 - 2e-07 31.2 0.0 3.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) bZIP_1 PF00170.16 OAP62563.1 - 0.46 10.4 14.1 0.72 9.8 9.8 1.2 1 0 0 1 1 1 0 bZIP transcription factor Acyl_transf_1 PF00698.16 OAP62564.1 - 1.6e-48 165.7 0.0 4.1e-48 164.3 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain DUF1729 PF08354.5 OAP62564.1 - 7.5e-29 99.2 0.0 2.2e-28 97.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 OAP62564.1 - 1.3e-25 89.1 0.0 3.8e-25 87.6 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAP62564.1 - 4.9e-07 29.5 0.0 2.7e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 OAP62564.1 - 0.0013 17.9 0.1 1 8.4 0.0 2.6 2 0 0 2 2 2 2 Nitronate monooxygenase Aminotran_4 PF01063.14 OAP62565.1 - 3e-16 59.5 0.0 5.1e-16 58.8 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class IV p450 PF00067.17 OAP62566.1 - 8.4e-71 238.8 0.0 1.1e-70 238.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.19 OAP62567.1 - 2.7e-50 171.3 0.0 3.1e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP62567.1 - 6.6e-05 22.7 0.3 0.007 16.1 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAP62567.1 - 0.0001 22.2 0.1 0.00048 20.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP62567.1 - 0.00029 20.9 0.0 0.072 13.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP62567.1 - 0.0019 16.7 0.0 0.23 9.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.19 OAP62567.1 - 0.009 15.1 0.0 0.22 10.5 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 OAP62567.1 - 0.079 11.8 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 OAP62567.1 - 0.1 11.7 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 OAP62567.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.2 OAP62568.1 - 5.7e-13 49.2 0.0 1e-12 48.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62568.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MOSC PF03473.12 OAP62569.1 - 3e-19 68.7 0.0 1.2e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 MOSC domain Fer2 PF00111.22 OAP62569.1 - 3.5e-12 45.8 2.0 7.5e-12 44.8 1.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.9 OAP62569.1 - 1.1e-05 24.9 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.16 OAP62569.1 - 0.022 15.3 0.1 0.15 12.6 0.1 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Glyco_hydro_3 PF00933.16 OAP62570.1 - 7.3e-90 300.9 0.0 1e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAP62570.1 - 1.4e-50 171.9 0.2 3.2e-49 167.4 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 OAP62570.1 - 2.4e-22 78.6 0.0 4.8e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2921 PF11145.3 OAP62571.1 - 0.13 9.9 0.3 0.19 9.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) DUF4059 PF13268.1 OAP62571.1 - 0.71 10.1 5.5 1.1 9.5 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Cation_efflux PF01545.16 OAP62572.1 - 5e-32 111.1 5.7 7.2e-32 110.5 3.9 1.1 1 0 0 1 1 1 1 Cation efflux family IF3_C PF00707.17 OAP62573.1 - 3.6e-13 49.0 3.7 4.1e-13 48.8 1.2 1.9 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 OAP62573.1 - 9.2e-07 28.3 8.1 1.7e-06 27.5 5.6 1.5 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Pep_M12B_propep PF01562.14 OAP62573.1 - 0.026 14.3 0.6 0.043 13.6 0.4 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide AAA_23 PF13476.1 OAP62573.1 - 7.4 6.8 9.5 9.6 6.4 6.6 1.2 1 0 0 1 1 1 0 AAA domain GDA1_CD39 PF01150.12 OAP62574.1 - 6.8e-95 318.1 0.0 8.7e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_C97 PF05903.9 OAP62575.1 - 1.1e-37 129.0 0.0 2.7e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 OAP62575.1 - 2.8e-26 91.9 0.0 5.3e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 OAP62575.1 - 1.3e-11 44.0 0.0 2.8e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAP62575.1 - 0.0002 21.5 0.1 0.00076 19.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2847 PF11009.3 OAP62575.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AhpC-TSA PF00578.16 OAP62575.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family EF-hand_9 PF14658.1 OAP62576.1 - 8.3e-06 25.6 0.0 0.0013 18.6 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain ORC6 PF05460.8 OAP62576.1 - 5.5e-05 22.4 0.5 5.7e-05 22.3 0.3 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_7 PF13499.1 OAP62576.1 - 0.019 15.0 0.1 0.31 11.1 0.0 2.7 4 0 0 4 4 4 0 EF-hand domain pair DUF2185 PF09951.4 OAP62576.1 - 0.11 12.3 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) PalH PF08733.5 OAP62578.1 - 8.9e-101 337.1 0.0 1.5e-100 336.4 0.0 1.3 1 1 0 1 1 1 1 PalH/RIM21 Abhydrolase_2 PF02230.11 OAP62579.1 - 5.3e-24 84.8 0.0 1.5e-16 60.4 0.1 2.8 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 OAP62579.1 - 1.1e-06 28.7 0.1 3.7e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP62579.1 - 1.9e-06 27.2 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP62579.1 - 8.4e-05 22.3 0.0 0.00033 20.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 OAP62579.1 - 0.069 12.3 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 Secretory lipase Zn_clus PF00172.13 OAP62580.1 - 6e-07 29.2 11.6 1e-06 28.5 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.4 OAP62581.1 - 4.6e-22 78.3 0.1 6.4e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 OAP62581.1 - 9.9e-05 21.5 7.0 0.00046 19.3 4.9 1.9 1 1 0 1 1 1 1 Autophagy protein Apg6 KorB PF08535.5 OAP62581.1 - 0.032 14.3 0.2 24 5.1 0.0 3.4 3 0 0 3 3 3 0 KorB domain DUF3557 PF12078.3 OAP62581.1 - 0.034 13.8 0.1 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) CAP PF00188.21 OAP62583.1 - 3.5e-11 43.6 1.8 4.6e-11 43.2 1.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Snf7 PF03357.16 OAP62584.1 - 3.8e-37 127.3 18.0 3.8e-37 127.3 12.5 1.5 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 OAP62584.1 - 0.0049 14.7 3.2 0.006 14.5 2.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ist1 PF03398.9 OAP62584.1 - 0.047 13.1 5.4 0.077 12.4 3.8 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Peptidase_S46 PF10459.4 OAP62584.1 - 0.2 10.0 6.4 0.24 9.7 4.4 1.1 1 0 0 1 1 1 0 Peptidase S46 YlqD PF11068.3 OAP62584.1 - 0.23 11.5 17.7 3.4 7.7 7.3 2.2 1 1 1 2 2 2 0 YlqD protein Remorin_C PF03763.8 OAP62584.1 - 1.6 8.2 8.4 2.3 7.8 5.2 1.7 1 1 0 1 1 1 0 Remorin, C-terminal region Dynamin_N PF00350.18 OAP62585.1 - 5.5e-18 65.3 0.0 5.5e-18 65.3 0.0 2.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 OAP62585.1 - 3.5e-09 36.6 0.2 2.4e-08 33.9 0.0 2.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAP62585.1 - 3.8e-07 29.7 1.9 2.2e-06 27.2 0.4 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 OAP62585.1 - 0.0069 15.2 0.0 0.048 12.4 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 OAP62585.1 - 0.014 15.7 0.4 0.051 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 OAP62585.1 - 0.017 15.6 0.3 0.69 10.4 0.2 2.8 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 OAP62585.1 - 0.08 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 OAP62585.1 - 0.14 11.3 2.2 30 3.8 0.1 3.7 4 0 0 4 4 4 0 Ferrous iron transport protein B PP2C PF00481.16 OAP62586.1 - 3.3e-63 213.4 0.5 3.4e-52 177.3 0.3 3.3 1 1 2 3 3 3 2 Protein phosphatase 2C Mit_KHE1 PF10173.4 OAP62586.1 - 0.011 15.6 0.1 0.036 13.9 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Pyr_redox_2 PF07992.9 OAP62587.1 - 8.6e-28 97.5 0.0 6.6e-17 62.0 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP62587.1 - 2.8e-13 50.0 0.0 1.9e-11 44.2 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP62587.1 - 0.0011 19.0 0.2 0.82 9.7 0.2 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L18e PF00828.14 OAP62588.1 - 1.1e-16 61.4 0.1 1.9e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 MFS_1 PF07690.11 OAP62589.1 - 3.6e-34 118.0 29.6 4.9e-34 117.5 20.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4064 PF13273.1 OAP62589.1 - 1.7 8.8 11.8 11 6.2 0.5 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) EcKinase PF02958.15 OAP62590.1 - 8.6e-26 90.7 0.0 2.2e-25 89.3 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 OAP62590.1 - 1.1e-19 71.1 0.1 2.3e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 OAP62590.1 - 9e-07 27.8 0.0 1.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 OAP62590.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase p450 PF00067.17 OAP62591.1 - 2.2e-61 207.7 0.0 3.2e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_90 PF05686.7 OAP62592.1 - 9.7e-15 54.1 7.8 5.3e-06 25.3 0.1 4.2 4 1 0 4 4 4 3 Glycosyl transferase family 90 Myotub-related PF06602.9 OAP62592.1 - 0.11 11.1 0.2 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Trypan_PARP PF05887.6 OAP62592.1 - 6 6.6 15.9 12 5.6 11.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spb1_C PF07780.7 OAP62593.1 - 1.9e-72 243.2 12.7 1.9e-72 243.2 8.8 3.5 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 OAP62593.1 - 7.9e-55 185.6 0.1 1.5e-54 184.7 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 OAP62593.1 - 2.7e-54 182.9 13.3 2.7e-54 182.9 9.2 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) Ribosomal_L4 PF00573.17 OAP62594.1 - 1.4e-44 151.7 0.0 2.2e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Fungal_trans PF04082.13 OAP62595.1 - 9.7e-39 132.7 0.3 1.4e-38 132.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP62595.1 - 3.9e-08 33.0 8.7 6.9e-08 32.2 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Snf7 PF03357.16 OAP62596.1 - 3.4e-19 68.8 19.7 7.9e-19 67.6 12.1 2.5 2 1 0 2 2 2 1 Snf7 MutS_III PF05192.13 OAP62596.1 - 3.1 7.5 10.7 5.9 6.6 6.2 2.3 1 1 1 2 2 2 0 MutS domain III Fib_alpha PF08702.5 OAP62596.1 - 7.6 6.6 14.6 1.2 9.3 1.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family zf-C3HC4 PF00097.20 OAP62597.1 - 1.1e-07 31.3 13.5 1.1e-07 31.3 9.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP62597.1 - 5.6e-07 29.4 13.9 5.6e-07 29.4 9.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP62597.1 - 1.6e-06 27.6 11.2 1.6e-06 27.6 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP62597.1 - 2.4e-06 27.1 13.2 2.4e-06 27.1 9.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAP62597.1 - 1.2e-05 25.0 13.8 1.2e-05 25.0 9.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 OAP62597.1 - 1.7e-05 24.4 8.2 4.8e-05 22.9 5.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAP62597.1 - 2.5e-05 24.0 13.0 2.5e-05 24.0 9.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 OAP62597.1 - 0.00012 21.8 4.4 0.00012 21.8 3.0 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C2HC_2 PF13913.1 OAP62597.1 - 0.0014 18.2 2.1 0.0044 16.6 1.5 2.0 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-RING_4 PF14570.1 OAP62597.1 - 0.0016 17.9 7.0 0.0016 17.9 4.9 2.6 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 OAP62597.1 - 0.0025 17.8 5.6 0.0025 17.8 3.8 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 OAP62597.1 - 0.02 14.8 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 U-box domain zf-Apc11 PF12861.2 OAP62597.1 - 6.6 6.6 8.5 0.41 10.5 2.3 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TRAPPC-Trs85 PF12739.2 OAP62598.1 - 4.7e-107 358.1 5.3 7e-107 357.6 2.9 1.6 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.12 OAP62598.1 - 0.99 9.4 5.9 2.4 8.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.22 OAP62599.1 - 2e-66 219.7 1.6 2.4e-21 75.2 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 OAP62599.1 - 4.4e-24 84.3 2.9 1.1e-13 51.0 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 OAP62599.1 - 5.1e-21 72.3 1.5 8.5e-07 27.8 0.5 4.5 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 OAP62599.1 - 3.5e-17 60.8 4.3 1.1e-06 27.6 0.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 OAP62599.1 - 4.4e-17 60.3 4.0 0.00028 20.5 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 OAP62599.1 - 4.5e-16 58.2 1.5 4.3e-09 35.8 0.0 3.6 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 OAP62599.1 - 2.2e-08 34.0 0.2 0.00011 22.1 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 OAP62599.1 - 0.0047 16.6 2.4 0.066 12.9 0.2 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 OAP62599.1 - 0.017 14.8 1.3 17 5.1 0.0 3.7 3 1 1 4 4 4 0 EF hand Cyclin_N PF00134.18 OAP62600.1 - 2.1e-12 46.7 0.6 3.4e-11 42.7 0.2 2.5 1 1 1 2 2 2 2 Cyclin, N-terminal domain TFCD_C PF12612.3 OAP62601.1 - 4.8e-24 84.8 1.8 4.8e-24 84.8 1.3 3.2 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 OAP62601.1 - 0.00023 20.9 7.6 0.012 15.6 0.0 5.9 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 OAP62601.1 - 0.00033 20.8 2.8 0.014 15.6 0.2 4.3 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 OAP62601.1 - 0.0087 16.5 0.1 0.0087 16.5 0.0 5.6 7 1 0 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAP62601.1 - 0.022 15.1 0.1 4.9 7.6 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region 2OG-FeII_Oxy_5 PF13759.1 OAP62602.1 - 0.035 14.3 0.0 0.092 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DNA_pol_B PF00136.16 OAP62603.1 - 4.8e-145 483.8 4.1 6.5e-145 483.4 2.9 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 OAP62603.1 - 1.6e-84 283.5 1.2 2.9e-84 282.7 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 OAP62603.1 - 1.6e-22 79.2 5.1 1.6e-22 79.2 3.6 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 OAP62603.1 - 0.00058 19.4 0.1 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 OAP62603.1 - 0.00077 19.3 0.2 0.0031 17.3 0.2 2.1 1 1 0 1 1 1 1 RNase_H superfamily DASH_Spc19 PF08287.6 OAP62603.1 - 0.0091 15.6 0.0 0.8 9.3 0.0 2.9 3 0 0 3 3 3 1 Spc19 C1_1 PF00130.17 OAP62603.1 - 0.026 14.2 7.8 0.12 12.1 1.0 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rho_GDI PF02115.12 OAP62604.1 - 1.5e-60 204.0 0.1 1.6e-60 203.9 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 OAP62605.1 - 1e-40 139.2 0.6 1.4e-40 138.8 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.20 OAP62607.1 - 5.5e-33 114.2 0.3 8.5e-33 113.6 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP62607.1 - 1.8e-15 57.0 0.1 4.1e-15 55.8 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP62607.1 - 1.8e-14 54.0 0.0 2.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAP62607.1 - 0.0014 18.3 0.2 0.0043 16.8 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 OAP62607.1 - 0.007 15.3 0.2 0.015 14.2 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 OAP62607.1 - 0.018 14.4 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP62607.1 - 0.028 14.4 1.0 0.056 13.4 0.2 2.0 2 1 0 2 2 2 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 OAP62607.1 - 0.03 13.3 1.2 0.38 9.8 0.1 2.8 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RasGEF PF00617.14 OAP62608.1 - 3.7e-62 209.3 0.6 7.9e-62 208.3 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAP62608.1 - 1.7e-28 98.7 0.1 4.4e-28 97.4 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 OAP62608.1 - 7e-15 54.1 0.6 2.4e-14 52.4 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 OAP62608.1 - 1.5e-13 50.1 0.1 3.7e-13 48.8 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAP62608.1 - 5.7e-10 38.5 0.0 1.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 OAP62608.1 - 3.2e-05 23.6 0.0 0.00012 21.8 0.0 2.0 1 0 0 1 1 1 1 WW domain FAD_binding_3 PF01494.14 OAP62609.1 - 1.7e-19 70.1 7.2 3.4e-15 55.9 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP62609.1 - 5.4e-12 45.2 7.3 8.9e-07 28.1 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP62609.1 - 2.2e-07 31.1 4.1 0.003 17.9 1.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP62609.1 - 7.5e-07 29.0 3.0 2.2e-06 27.5 2.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAP62609.1 - 4.1e-06 27.0 0.1 1e-05 25.7 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP62609.1 - 7.3e-05 22.0 1.2 0.00012 21.3 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP62609.1 - 7.6e-05 22.6 4.2 0.00056 19.8 2.9 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP62609.1 - 0.00011 21.4 3.5 0.16 11.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 OAP62609.1 - 0.00026 20.1 1.3 0.00045 19.3 0.9 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 OAP62609.1 - 0.00094 18.1 0.4 0.0014 17.6 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 OAP62609.1 - 0.0011 17.6 4.6 0.34 9.4 0.0 2.6 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 OAP62609.1 - 0.0015 17.5 0.4 0.0039 16.1 0.3 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP62609.1 - 0.0016 17.3 9.2 0.0046 15.8 4.8 2.1 2 0 0 2 2 2 1 FAD binding domain SE PF08491.5 OAP62609.1 - 0.0049 15.7 0.0 0.011 14.5 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase PaRep2a PF07903.6 OAP62609.1 - 0.014 15.0 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 PaRep2a protein HI0933_like PF03486.9 OAP62609.1 - 0.019 13.4 7.0 0.13 10.7 3.1 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 OAP62609.1 - 0.2 11.4 5.5 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 OAP62610.1 - 3.8e-16 58.7 2.6 6.3e-16 58.0 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 OAP62610.1 - 6.8e-07 29.2 17.8 3.4e-05 23.8 4.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP62610.1 - 2.7e-06 27.3 13.7 0.0018 18.4 3.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP62610.1 - 1.5e-05 25.0 14.7 0.0065 16.7 3.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type PyrI_C PF02748.10 OAP62610.1 - 1.2 8.6 3.9 0.48 9.8 0.6 1.9 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 OAP62610.1 - 2 8.4 6.4 4.9 7.1 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger DivIC PF04977.10 OAP62611.1 - 0.00066 19.1 2.8 0.00066 19.1 2.0 3.5 3 0 0 3 3 3 1 Septum formation initiator bZIP_2 PF07716.10 OAP62611.1 - 0.00095 18.9 26.9 0.066 13.0 1.8 4.6 4 1 1 5 5 5 4 Basic region leucine zipper bZIP_1 PF00170.16 OAP62611.1 - 0.0073 16.2 16.7 0.66 9.9 3.6 3.6 3 0 0 3 3 3 3 bZIP transcription factor ADIP PF11559.3 OAP62611.1 - 0.01 15.7 1.9 0.01 15.7 1.3 3.3 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding Cortex-I_coil PF09304.5 OAP62611.1 - 0.026 14.5 2.3 0.026 14.5 1.6 3.5 4 1 0 4 4 4 0 Cortexillin I, coiled coil Seryl_tRNA_N PF02403.17 OAP62611.1 - 0.81 9.7 9.5 0.14 12.1 1.0 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PAH PF02671.16 OAP62611.1 - 1.1 8.9 3.3 0.71 9.5 0.1 2.3 3 0 0 3 3 3 0 Paired amphipathic helix repeat WD40_alt PF14077.1 OAP62611.1 - 1.2 8.8 6.0 2.6 7.7 0.0 3.4 3 0 0 3 3 3 0 Alternative WD40 repeat motif HALZ PF02183.13 OAP62611.1 - 2 8.2 11.6 7.3 6.3 0.3 3.6 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF904 PF06005.7 OAP62611.1 - 3.5 7.9 15.2 2.1 8.7 2.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 OAP62611.1 - 7 7.1 11.2 16 6.0 3.3 3.0 2 2 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 OAP62611.1 - 8.4 6.7 14.5 1.1 9.5 1.2 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF972) TSC22 PF01166.13 OAP62611.1 - 9.2 6.3 11.6 12 5.9 1.6 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family UQ_con PF00179.21 OAP62612.1 - 1.5e-19 69.8 0.0 2.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Lin-8 PF03353.10 OAP62612.1 - 0.053 12.7 3.8 0.078 12.2 2.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.8 OAP62612.1 - 9.1 6.0 13.5 14 5.4 9.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-DHHC PF01529.15 OAP62613.1 - 2.8e-17 62.6 5.3 4.5e-17 61.9 3.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 OAP62613.1 - 0.0013 18.2 2.0 0.0022 17.5 1.4 1.2 1 0 0 1 1 1 1 Yip1 domain Acetyltransf_1 PF00583.19 OAP62614.1 - 2.1e-07 30.8 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP62614.1 - 4.1e-07 30.0 0.0 6.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP62614.1 - 7.6e-05 22.8 0.0 0.0009 19.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP62614.1 - 0.00019 21.2 0.0 0.00078 19.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP62614.1 - 0.0038 16.9 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 OAP62614.1 - 0.007 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Sugar_tr PF00083.19 OAP62615.1 - 7.3e-113 377.5 22.3 8.3e-113 377.3 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62615.1 - 4.6e-20 71.6 45.0 4.6e-17 61.7 7.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.4 OAP62616.1 - 8.6e-122 406.2 3.6 3.3e-119 397.7 2.5 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) TSC21 PF15217.1 OAP62616.1 - 0.038 13.6 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 TSC21 family RPA_C PF08784.6 OAP62617.1 - 6.1e-17 61.9 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 OAP62617.1 - 3.3e-07 30.0 0.0 7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Polysacc_syn_2C PF08485.5 OAP62617.1 - 0.089 12.3 0.0 0.84 9.1 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal DEAD PF00270.24 OAP62618.1 - 3.5e-46 156.7 0.3 1.5e-45 154.7 0.0 2.1 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP62618.1 - 3.9e-23 81.0 0.1 8.4e-23 80.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 OAP62618.1 - 8.1e-21 73.6 3.3 1.8e-20 72.4 2.3 1.6 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DUF2788 PF10981.3 OAP62619.1 - 0.11 12.2 0.3 0.11 12.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2788) Abi PF02517.11 OAP62619.1 - 5.8 7.1 6.7 0.56 10.3 1.4 1.7 2 0 0 2 2 2 0 CAAX protease self-immunity LDB19 PF13002.2 OAP62620.1 - 3.7e-48 163.5 0.4 7.6e-48 162.5 0.2 1.5 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 OAP62620.1 - 0.0082 15.9 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Oxidored_molyb PF00174.14 OAP62621.1 - 2.7e-49 166.8 0.0 4.5e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 OAP62621.1 - 2.8e-24 85.2 4.5 5.7e-24 84.2 3.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Epimerase PF01370.16 OAP62622.1 - 5.9e-16 58.6 0.0 7.8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP62622.1 - 5.3e-11 41.7 0.0 7.1e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAP62622.1 - 3.4e-09 35.9 0.0 1.1e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 OAP62622.1 - 1.1e-05 25.5 0.0 3e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAP62622.1 - 0.033 14.1 0.0 0.26 11.2 0.0 2.2 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 OAP62622.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DUF3866 PF12982.2 OAP62622.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) SNF2_N PF00176.18 OAP62623.1 - 5.8e-70 235.4 0.0 7.9e-70 234.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 OAP62623.1 - 5.5e-22 77.7 0.0 1.2e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 OAP62623.1 - 7.6e-13 48.1 0.0 1.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 OAP62623.1 - 3.3e-07 30.2 8.7 6.1e-07 29.3 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP62623.1 - 8.6e-06 25.3 5.7 1.5e-05 24.5 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP62623.1 - 0.00062 19.3 8.6 0.0012 18.4 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C_4 PF13871.1 OAP62623.1 - 0.0014 18.0 0.0 0.033 13.6 0.1 2.3 2 0 0 2 2 2 1 Helicase_C-like zf-RING_2 PF13639.1 OAP62623.1 - 0.002 17.8 6.6 0.0039 16.9 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAP62623.1 - 0.0025 17.5 6.6 0.0049 16.5 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAP62623.1 - 0.0057 16.3 6.0 0.014 15.1 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger UBA_4 PF14555.1 OAP62623.1 - 0.0061 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Cut8_N PF14482.1 OAP62623.1 - 0.22 11.5 5.5 1.9 8.5 1.9 2.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain zf-C3HC4_4 PF15227.1 OAP62623.1 - 0.34 10.8 6.2 0.74 9.7 4.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.14 OAP62624.1 - 5e-45 153.8 0.0 7.8e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase UPF0052 PF01933.13 OAP62625.1 - 1.7e-52 178.6 0.0 2.3e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 CorA PF01544.13 OAP62626.1 - 1.1e-30 106.7 4.2 2.3e-20 72.8 0.1 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein YL1 PF05764.8 OAP62626.1 - 0.0011 18.6 4.0 0.0019 17.8 2.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Methyltransf_12 PF08242.7 OAP62626.1 - 0.0097 16.3 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Spt5_N PF11942.3 OAP62626.1 - 5.8 7.6 12.2 0.69 10.5 4.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-C3HC4_2 PF13923.1 OAP62627.1 - 8.1e-10 38.5 5.2 2.6e-09 36.9 3.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP62627.1 - 1.9e-09 37.0 5.9 3.4e-09 36.2 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP62627.1 - 3.6e-09 36.2 6.7 5.8e-09 35.6 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAP62627.1 - 4.1e-09 35.9 3.2 1.3e-08 34.3 2.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP62627.1 - 2.5e-08 33.5 5.6 5e-08 32.5 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAP62627.1 - 1.1e-07 31.6 4.0 1.5e-07 31.1 0.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAP62627.1 - 8.9e-06 25.3 2.6 0.00018 21.1 0.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 OAP62627.1 - 0.00053 19.4 0.1 0.0012 18.2 0.1 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 OAP62627.1 - 0.0029 17.0 1.5 0.056 12.9 0.1 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-rbx1 PF12678.2 OAP62627.1 - 0.03 14.4 5.6 0.2 11.7 4.2 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 OAP62627.1 - 0.052 13.0 8.9 0.71 9.4 2.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 OAP62627.1 - 0.071 12.7 6.8 0.31 10.6 4.8 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 OAP62627.1 - 0.09 12.6 6.2 3.3 7.6 4.3 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.16 OAP62627.1 - 0.15 11.9 5.1 0.34 10.8 3.5 1.7 1 1 0 1 1 1 0 FYVE zinc finger FANCL_C PF11793.3 OAP62627.1 - 0.17 11.8 4.2 0.7 9.8 2.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 OAP62627.1 - 0.75 9.6 8.2 11 5.8 3.8 2.9 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 OAP62627.1 - 1.5 8.3 4.7 0.49 9.9 1.5 1.6 1 1 0 1 1 1 0 Transposase zinc-binding domain Baculo_IE-1 PF05290.6 OAP62627.1 - 2.7 7.6 5.8 6.5 6.4 4.0 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) AMP-binding PF00501.23 OAP62628.1 - 7.3e-45 153.0 0.0 1.1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP62628.1 - 0.00061 20.6 0.1 0.0026 18.6 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 OAP62629.1 - 7.9e-60 202.7 0.0 1.4e-59 201.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAP62629.1 - 0.001 18.3 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 OAP62629.1 - 0.034 12.8 0.0 0.071 11.8 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAP62629.1 - 0.062 11.5 0.0 0.12 10.6 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme FAA_hydrolase PF01557.13 OAP62631.1 - 1.5e-59 201.0 0.1 2.6e-59 200.3 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 OAP62631.1 - 1.1e-38 133.3 1.5 3.3e-38 131.8 1.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62631.1 - 1.7e-19 70.3 0.0 7.3e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP62631.1 - 1.9e-18 66.6 0.3 8.5e-18 64.4 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_5 PF13594.1 OAP62631.1 - 2.9e-08 33.4 0.0 2.3e-07 30.4 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 OAP62631.1 - 3.5e-06 26.9 0.9 9.6e-06 25.4 0.6 1.8 1 1 0 1 1 1 1 Amidohydrolase family Hydrolase_4 PF12146.3 OAP62631.1 - 4e-06 26.5 0.2 2.8e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 OAP62631.1 - 0.00019 21.2 0.0 0.0015 18.4 0.0 2.6 3 0 0 3 3 3 1 TAP-like protein Ser_hydrolase PF06821.8 OAP62631.1 - 0.00021 20.9 0.5 0.012 15.2 0.0 2.7 2 1 1 3 3 3 1 Serine hydrolase BAAT_C PF08840.6 OAP62631.1 - 0.00057 19.6 0.0 0.002 17.8 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Amidohydro_3 PF07969.6 OAP62631.1 - 0.0014 17.9 1.7 0.01 15.0 0.1 2.8 2 1 0 3 3 3 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAP62631.1 - 0.0015 18.6 1.5 0.0085 16.1 0.7 2.7 2 1 0 2 2 2 1 Amidohydrolase Ndr PF03096.9 OAP62631.1 - 0.0025 16.3 0.0 0.0039 15.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.15 OAP62631.1 - 0.039 14.1 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 OAP62631.1 - 0.068 12.7 0.2 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) BAP PF06639.6 OAP62631.1 - 0.17 11.6 1.5 4.3 7.1 0.1 2.6 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) Fungal_trans PF04082.13 OAP62632.1 - 1.5e-14 53.5 0.1 2.3e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP62632.1 - 2.2e-07 30.6 12.8 4.5e-07 29.6 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRI12 PF06609.8 OAP62633.1 - 4.4e-50 170.4 16.3 5.6e-50 170.1 11.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP62633.1 - 1.1e-20 73.6 48.0 1.1e-20 73.6 33.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP62633.1 - 6.4e-11 41.4 4.0 6.4e-11 41.4 2.8 3.5 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 OAP62634.1 - 5.4e-53 180.1 20.4 7e-53 179.7 14.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP62634.1 - 1.4e-31 109.5 42.5 1.4e-31 109.5 29.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP62634.1 - 1.2e-11 43.9 16.3 1.2e-11 43.9 11.3 3.8 3 1 1 4 4 4 1 Sugar (and other) transporter MFS_3 PF05977.8 OAP62634.1 - 0.0002 19.6 16.2 0.0042 15.2 1.1 3.2 2 1 1 3 3 3 3 Transmembrane secretion effector Myco_19_kDa PF05481.7 OAP62634.1 - 0.19 11.5 3.8 0.059 13.1 0.3 1.8 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen DUF2823 PF11034.3 OAP62636.1 - 5e-22 77.8 3.5 5.7e-22 77.6 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) ETC_C1_NDUFA4 PF04800.7 OAP62637.1 - 2e-34 117.4 0.4 2.9e-34 116.9 0.3 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region PhzC-PhzF PF02567.11 OAP62638.1 - 3e-39 134.9 4.0 2.5e-38 131.9 2.8 2.3 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Catalase PF00199.14 OAP62639.1 - 2.7e-159 529.9 0.0 3.8e-159 529.4 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAP62639.1 - 2e-18 66.0 0.0 4.1e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 OAP62639.1 - 2.4e-09 36.7 0.0 6.6e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family PQ-loop PF04193.9 OAP62640.1 - 1.7e-29 101.1 7.2 2.2e-18 65.5 1.5 2.4 2 0 0 2 2 2 2 PQ loop repeat Lactamase_B PF00753.22 OAP62640.1 - 6.6e-23 81.3 0.6 1.1e-22 80.6 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP62640.1 - 0.0014 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain YrhC PF14143.1 OAP62640.1 - 0.49 10.3 2.1 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 YrhC-like protein NUC153 PF08159.7 OAP62642.1 - 2.7e-15 55.6 8.4 3.6e-13 48.8 0.2 4.0 3 0 0 3 3 3 3 NUC153 domain Epimerase PF01370.16 OAP62643.1 - 9.5e-44 149.5 0.0 1.4e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 OAP62643.1 - 1.5e-26 92.1 0.1 2.7e-26 91.2 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 OAP62643.1 - 1e-17 63.7 0.0 1.4e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAP62643.1 - 2.2e-13 49.7 0.0 3.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 OAP62643.1 - 6.2e-13 48.2 0.0 2.3e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 OAP62643.1 - 3.6e-10 39.9 0.0 6.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 OAP62643.1 - 1.4e-08 34.0 0.0 1e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 OAP62643.1 - 3.5e-07 30.3 0.0 6.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 OAP62643.1 - 2.1e-06 27.4 0.0 4.6e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 OAP62643.1 - 0.0091 15.2 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family DAO PF01266.19 OAP62643.1 - 0.012 14.5 0.2 0.024 13.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 OAP62643.1 - 0.025 13.9 0.1 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 OAP62643.1 - 0.14 12.7 0.0 26 5.4 0.0 2.6 3 0 0 3 3 2 0 Methyltransferase domain FAD_binding_3 PF01494.14 OAP62644.1 - 4e-17 62.3 1.2 6.2e-15 55.1 0.9 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAP62644.1 - 0.028 14.4 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3722 PF12519.3 OAP62645.1 - 4.1e-72 242.5 0.5 5.8e-72 242.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Aa_trans PF01490.13 OAP62646.1 - 3.6e-22 78.4 36.0 4.4e-22 78.1 25.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBV_3C PF03620.8 OAP62646.1 - 0.0067 16.3 0.4 0.0067 16.3 0.3 2.8 3 0 0 3 3 3 1 IBV 3C protein NADH_Oxid_Nqo15 PF11497.3 OAP62646.1 - 0.097 12.3 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 Abhydrolase_6 PF12697.2 OAP62647.1 - 8.4e-34 117.4 0.2 1e-33 117.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62647.1 - 1.8e-08 34.2 0.0 8.7e-07 28.7 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP62647.1 - 8.1e-08 32.1 0.0 1.9e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family TPR_7 PF13176.1 OAP62647.1 - 0.016 14.9 0.0 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Amidohydro_1 PF01979.15 OAP62647.1 - 0.044 13.4 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase family Abhydrolase_3 PF07859.8 OAP62648.1 - 6.7e-09 35.6 0.0 5e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP62648.1 - 3.9e-07 29.5 0.0 6.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP62648.1 - 4.1e-07 29.8 0.0 5.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP62648.1 - 1.4e-06 28.3 0.1 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 OAP62648.1 - 1.1e-05 24.3 0.0 1.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 OAP62648.1 - 0.0014 17.4 0.1 0.0023 16.6 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Pyr_redox_3 PF13738.1 OAP62649.1 - 5.1e-09 36.4 3.4 0.0013 18.8 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP62649.1 - 3e-08 32.3 0.0 3e-05 22.4 0.0 2.5 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP62649.1 - 0.00012 21.1 1.2 0.013 14.4 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP62649.1 - 0.00025 20.9 0.0 0.0085 15.9 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP62649.1 - 0.014 14.4 2.4 0.014 14.4 1.7 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 OAP62649.1 - 0.057 13.8 0.3 2 8.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP62649.1 - 0.48 9.2 4.4 0.5 9.1 1.9 1.8 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 OAP62649.1 - 3.7 6.3 6.2 11 4.7 2.7 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase adh_short PF00106.20 OAP62650.1 - 5.3e-06 26.4 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAP62650.1 - 0.00086 19.3 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP62650.1 - 0.018 14.2 0.1 0.064 12.5 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family 2-Hacid_dh_C PF02826.14 OAP62650.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 OAP62651.1 - 2.5e-33 115.8 0.9 2.8e-33 115.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP62651.1 - 1.2e-22 80.6 3.2 1.5e-22 80.3 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62651.1 - 5.7e-09 35.8 1.2 8.6e-09 35.3 0.9 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 OAP62651.1 - 0.0026 17.3 0.3 0.0041 16.7 0.2 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus Dak1_2 PF13684.1 OAP62651.1 - 0.0095 14.9 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Dihydroxyacetone kinase family 2-Hacid_dh_C PF02826.14 OAP62651.1 - 0.033 13.3 2.1 0.051 12.7 0.6 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 OAP62651.1 - 0.054 12.4 1.4 0.13 11.1 0.3 2.0 2 1 1 3 3 3 0 Male sterility protein DFP PF04127.10 OAP62651.1 - 0.13 11.8 4.1 0.52 9.8 2.8 1.9 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein HHH_5 PF14520.1 OAP62651.1 - 0.16 12.1 0.9 8.3 6.6 0.4 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix domain DUF2620 PF10941.3 OAP62651.1 - 0.49 10.4 4.7 12 5.9 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF2620 3HCDH_N PF02737.13 OAP62651.1 - 2 8.0 8.3 0.039 13.6 1.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 OAP62652.1 - 1.6e-22 80.0 0.0 3.1e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 OAP62652.1 - 0.0082 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 OAP62652.1 - 0.014 15.3 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SHOCT PF09851.4 OAP62652.1 - 0.035 13.5 2.1 0.046 13.2 0.1 2.1 2 0 0 2 2 2 0 Short C-terminal domain Pyr_redox_2 PF07992.9 OAP62652.1 - 0.095 12.5 0.2 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 OAP62652.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AraC_binding PF02311.14 OAP62653.1 - 0.0037 16.9 0.0 0.0086 15.7 0.0 1.5 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.6 OAP62653.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain IF-2B PF01008.12 OAP62656.1 - 2e-16 59.8 0.9 1.9e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Initiation factor 2 subunit family NUDIX PF00293.23 OAP62656.1 - 1.8e-09 37.3 0.1 3.7e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.19 OAP62657.1 - 1.5e-118 396.2 24.4 1.8e-118 395.9 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62657.1 - 3e-25 88.6 46.9 8.2e-21 74.1 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.6 OAP62657.1 - 0.02 14.3 1.3 0.02 14.3 0.9 4.0 4 1 0 4 4 4 0 7TM receptor with intracellular HD hydrolase DUF3154 PF11351.3 OAP62657.1 - 0.043 13.5 0.3 0.47 10.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Zn_clus PF00172.13 OAP62658.1 - 5.2e-06 26.2 11.6 9.1e-06 25.4 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP62659.1 - 3.4e-25 88.5 21.6 3.4e-25 88.5 15.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.15 OAP62659.1 - 1.8 7.8 11.6 1.3 8.3 1.2 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF21 Amidohydro_3 PF07969.6 OAP62660.1 - 2.7e-55 188.2 6.1 3.3e-55 187.9 4.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 OAP62660.1 - 8.2e-10 38.3 0.0 2.2e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 OAP62660.1 - 3e-07 30.3 0.3 0.0024 17.5 0.2 3.1 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 OAP62660.1 - 3.3e-07 30.6 9.8 0.00014 22.0 0.0 2.4 1 1 1 2 2 2 2 Amidohydrolase Asp PF00026.18 OAP62661.1 - 4.3e-67 226.6 10.0 5.3e-67 226.3 6.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAP62661.1 - 1.7e-09 37.8 0.2 5.1e-08 33.0 0.0 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAP62661.1 - 9.5e-05 22.8 4.5 0.015 15.8 0.2 3.6 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 OAP62661.1 - 0.0087 15.6 0.1 0.039 13.4 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal DUF462 PF04315.7 OAP62661.1 - 0.026 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF462 Lipocalin_6 PF13944.1 OAP62661.1 - 0.037 14.1 0.6 0.1 12.6 0.2 1.9 2 0 0 2 2 2 0 Lipocalin-like domain Fimbrial_PilY2 PF14481.1 OAP62661.1 - 0.048 13.0 0.4 0.12 11.8 0.3 1.6 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 zf-C3HC4_3 PF13920.1 OAP62662.1 - 2.6e-08 33.3 12.0 4.3e-08 32.7 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FbpA PF05833.6 OAP62662.1 - 0.22 10.0 0.2 0.31 9.5 0.1 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Herpes_LMP1 PF05297.6 OAP62662.1 - 0.25 10.2 0.0 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) TFIIF_alpha PF05793.7 OAP62662.1 - 0.35 9.1 0.8 0.52 8.6 0.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C3HC4_2 PF13923.1 OAP62662.1 - 9.5 6.3 14.9 17 5.5 10.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4449 PF14613.1 OAP62664.1 - 1.3e-65 220.2 4.1 1.3e-65 220.2 2.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.10 OAP62664.1 - 1.5 8.6 11.5 2 8.2 0.0 3.3 3 1 1 4 4 4 0 Prp18 domain DUF4211 PF13926.1 OAP62665.1 - 2.3e-31 108.2 0.5 1.3e-30 105.8 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) ResB PF05140.9 OAP62665.1 - 0.2 10.1 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 ResB-like family DNA_pol_alpha_N PF12254.3 OAP62665.1 - 2 8.3 17.3 2 8.3 1.0 4.3 3 1 1 4 4 4 0 DNA polymerase alpha subunit p180 N terminal Tom22 PF04281.8 OAP62666.1 - 4.3e-42 142.9 0.2 4.8e-42 142.7 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 TIM PF00121.13 OAP62667.1 - 3.6e-90 301.3 0.0 4e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 OAP62667.1 - 0.033 13.4 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 CutC family OB_NTP_bind PF07717.11 OAP62668.1 - 8.6e-26 90.0 0.0 2e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAP62668.1 - 3.8e-23 81.4 0.2 1.4e-22 79.5 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAP62668.1 - 1.5e-11 43.9 0.0 5.6e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP62668.1 - 4.5e-07 29.5 0.3 1.1e-06 28.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAP62668.1 - 2.6e-06 27.5 0.2 9.8e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 OAP62668.1 - 0.00015 21.2 0.1 0.00039 19.9 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 OAP62668.1 - 0.00044 20.0 0.1 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 OAP62668.1 - 0.0046 15.8 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 OAP62668.1 - 0.0055 16.5 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_16 PF13191.1 OAP62668.1 - 0.069 13.1 0.0 0.27 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 OAP62668.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 OAP62668.1 - 0.18 11.3 0.0 0.58 9.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 OAP62668.1 - 0.18 12.1 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain EphA2_TM PF14575.1 OAP62669.1 - 0.028 14.7 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LAT PF15234.1 OAP62669.1 - 0.43 10.0 4.0 0.12 11.8 0.1 1.9 1 1 1 2 2 2 0 Linker for activation of T-cells TMEM154 PF15102.1 OAP62669.1 - 0.52 10.0 2.4 1.1 8.9 1.7 1.5 1 1 0 1 1 1 0 TMEM154 protein family tRNA_U5-meth_tr PF05958.6 OAP62670.1 - 5.3e-15 54.9 0.0 2e-14 53.0 0.0 1.9 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 OAP62670.1 - 1.7e-06 28.0 0.0 3.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAP62670.1 - 1.9e-06 27.2 0.0 3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 OAP62670.1 - 1.1e-05 25.0 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 OAP62670.1 - 1.4e-05 24.7 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 OAP62670.1 - 1.4e-05 25.6 0.0 2.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP62670.1 - 0.00042 20.7 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP62670.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.11 OAP62670.1 - 0.025 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 OAP62670.1 - 0.05 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Actin PF00022.14 OAP62672.1 - 2.4e-89 299.5 0.0 5.4e-89 298.3 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAP62672.1 - 0.027 13.0 0.0 0.85 8.1 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 OAP62673.1 - 5.2e-35 120.6 1.5 1.1e-21 76.9 0.0 2.2 2 0 0 2 2 2 2 Asparaginase MBT PF02820.13 OAP62673.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 mbt repeat Tfb4 PF03850.9 OAP62674.1 - 4.7e-90 301.5 0.0 8.4e-54 182.6 0.0 2.5 2 1 0 2 2 2 2 Transcription factor Tfb4 UNC45-central PF11701.3 OAP62675.1 - 1.5e-29 102.7 0.0 3.1e-28 98.4 0.0 3.1 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.4 OAP62675.1 - 0.016 14.9 0.0 0.16 11.7 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 OAP62675.1 - 0.18 11.6 11.0 11 6.0 0.0 6.3 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat THOC7 PF05615.8 OAP62676.1 - 0.12 12.6 15.0 1.7 8.9 0.3 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 BLOC1_2 PF10046.4 OAP62676.1 - 0.49 10.5 8.3 0.12 12.5 0.7 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 OAP62676.1 - 2.7 7.5 24.2 0.63 9.6 9.5 2.9 3 0 0 3 3 3 0 IncA protein DSPc PF00782.15 OAP62678.1 - 9.8e-29 99.6 0.0 1.3e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAP62678.1 - 6.3e-06 25.7 0.1 0.00023 20.5 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Cupin_8 PF13621.1 OAP62679.1 - 1.7e-31 109.6 0.0 2.9e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 OAP62679.1 - 4.1e-21 75.3 0.0 8.9e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 OAP62679.1 - 4.1e-08 32.8 7.4 1.9e-06 27.5 0.0 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.1 OAP62679.1 - 0.0013 18.8 1.6 0.85 9.8 0.1 4.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 OAP62679.1 - 0.016 15.1 0.1 1.8 8.6 0.0 3.1 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 OAP62679.1 - 0.022 14.5 0.4 10 6.0 0.0 2.9 2 0 0 2 2 2 0 Kelch motif TAP42 PF04177.7 OAP62680.1 - 4.9e-100 334.8 0.4 5.5e-100 334.6 0.2 1.0 1 0 0 1 1 1 1 TAP42-like family HisKA PF00512.20 OAP62680.1 - 0.017 15.1 0.1 0.053 13.5 0.1 1.9 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Porphobil_deam PF01379.15 OAP62681.1 - 2.6e-72 242.2 0.0 4e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 OAP62681.1 - 3e-15 56.0 0.0 5.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.8 OAP62682.1 - 1.1e-73 246.9 0.7 7.3e-73 244.2 0.5 2.3 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 OAP62682.1 - 4.9e-28 98.2 0.6 1.1e-27 97.0 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 OAP62682.1 - 2.1e-23 82.9 0.0 5e-22 78.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 OAP62682.1 - 8.5e-08 31.7 0.0 2.2e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 OAP62682.1 - 9.9e-08 31.8 0.0 2.5e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 OAP62682.1 - 8e-06 24.8 0.0 7.1e-05 21.6 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_16 PF13191.1 OAP62682.1 - 9.3e-06 25.7 0.6 3.2e-05 23.9 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 OAP62682.1 - 2.9e-05 23.5 0.0 6.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 OAP62682.1 - 5.9e-05 22.6 0.0 0.00023 20.7 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAP62682.1 - 0.0001 23.0 0.0 0.00054 20.7 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP62682.1 - 0.00012 21.7 0.0 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 OAP62682.1 - 0.00016 20.8 0.0 0.0027 16.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Birna_VP4 PF01768.11 OAP62682.1 - 0.00033 19.8 0.1 0.00083 18.4 0.0 1.6 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_22 PF13401.1 OAP62682.1 - 0.00037 20.6 0.0 0.003 17.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 OAP62682.1 - 0.00078 19.3 0.0 0.0026 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 OAP62682.1 - 0.00088 18.7 0.0 0.0024 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAP62682.1 - 0.0039 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAP62682.1 - 0.0057 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAP62682.1 - 0.0058 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.1 OAP62682.1 - 0.013 15.8 0.0 0.013 15.8 0.0 2.8 1 1 0 2 2 1 0 AAA domain PhoH PF02562.11 OAP62682.1 - 0.014 14.6 0.0 0.034 13.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 OAP62682.1 - 0.017 14.7 0.1 0.087 12.4 0.0 2.3 3 0 0 3 3 1 0 NACHT domain UPF0079 PF02367.12 OAP62682.1 - 0.022 14.3 0.1 0.066 12.8 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 OAP62682.1 - 0.03 14.6 0.1 0.11 12.7 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 OAP62682.1 - 0.038 13.5 0.1 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 OAP62682.1 - 0.038 13.1 0.1 0.09 11.9 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 OAP62682.1 - 0.04 12.6 0.1 0.44 9.1 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain Hydrolase_like PF13242.1 OAP62682.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like AAA_11 PF13086.1 OAP62682.1 - 0.05 13.1 0.9 0.26 10.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAP62682.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 OAP62682.1 - 0.074 13.3 0.1 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DUF2461 PF09365.5 OAP62682.1 - 0.14 11.4 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Ribosomal_L23 PF00276.15 OAP62683.1 - 3.2e-13 49.4 0.0 5.5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 PC_rep PF01851.17 OAP62684.1 - 2.6e-21 74.5 12.9 3.3e-05 23.8 0.1 9.2 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 OAP62684.1 - 1.2e-07 31.8 0.3 0.031 14.5 0.0 5.0 4 1 0 4 4 4 2 HEAT repeats TPR_5 PF12688.2 OAP62684.1 - 0.057 13.4 0.2 2.8 8.0 0.0 2.8 2 0 0 2 2 2 0 Tetratrico peptide repeat MFS_1 PF07690.11 OAP62685.1 - 3.1e-16 59.0 15.5 8e-16 57.6 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 OAP62685.1 - 0.0018 17.5 5.5 0.006 15.8 1.8 2.4 2 1 0 2 2 2 1 Nodulin-like Transglut_core PF01841.14 OAP62686.1 - 1.2e-11 44.7 0.0 2.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 OAP62686.1 - 0.023 13.9 0.0 0.33 10.2 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like domain NmrA PF05368.8 OAP62687.1 - 7.7e-23 80.9 0.0 9.2e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP62687.1 - 6.8e-14 52.2 0.0 9.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 OAP62687.1 - 9.3e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 OAP62687.1 - 5.9e-05 22.9 0.1 0.00019 21.3 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 OAP62687.1 - 7.7e-05 21.8 0.0 0.0001 21.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 OAP62687.1 - 0.0004 20.4 0.0 0.00079 19.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 OAP62687.1 - 0.0014 18.1 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP62687.1 - 0.0015 17.5 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein GFO_IDH_MocA PF01408.17 OAP62687.1 - 0.0029 18.1 0.0 0.0048 17.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.11 OAP62687.1 - 0.011 16.3 0.1 0.13 12.8 0.0 2.2 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.14 OAP62687.1 - 0.041 12.5 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2874 PF11396.3 OAP62687.1 - 0.078 12.9 0.3 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) IBR PF01485.16 OAP62688.1 - 6.3e-11 41.9 38.2 2e-05 24.3 10.8 3.6 2 2 1 3 3 3 2 IBR domain zf-RING_2 PF13639.1 OAP62688.1 - 4.3e-06 26.4 7.7 4.3e-06 26.4 5.4 3.8 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP62688.1 - 3.4e-05 23.7 4.3 3.4e-05 23.7 3.0 4.8 2 2 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP62688.1 - 0.0031 17.1 7.2 0.0031 17.1 5.0 4.1 2 1 0 2 2 1 1 zinc-RING finger domain RWD PF05773.17 OAP62688.1 - 0.0032 17.3 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.20 OAP62688.1 - 0.0032 17.0 6.4 0.0032 17.0 4.4 3.8 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAP62688.1 - 0.026 14.4 6.1 0.026 14.4 4.2 3.8 3 2 0 3 3 1 0 zinc finger of C3HC4-type, RING zf-ribbon_3 PF13248.1 OAP62688.1 - 0.075 12.2 0.1 0.075 12.2 0.1 3.4 4 1 1 5 5 5 0 zinc-ribbon domain UPF0547 PF10571.4 OAP62688.1 - 0.14 11.8 11.7 1.2 8.9 0.1 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 OAP62688.1 - 0.96 9.0 0.0 0.96 9.0 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_UBOX PF13445.1 OAP62688.1 - 2 8.1 9.7 4 7.2 3.6 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Sugar_tr PF00083.19 OAP62689.1 - 7.5e-89 298.3 33.6 1.5e-86 290.8 23.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62689.1 - 1.2e-21 76.8 29.8 1.2e-21 76.8 20.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily OppC_N PF12911.2 OAP62689.1 - 0.029 13.7 0.3 0.82 9.0 0.0 3.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C adh_short PF00106.20 OAP62690.1 - 5.4e-20 71.9 2.0 1.9e-19 70.1 1.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP62690.1 - 4.4e-16 59.3 1.2 2.4e-15 57.0 0.8 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP62690.1 - 2.9e-09 36.8 0.3 4.4e-09 36.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP62690.1 - 1.5e-07 31.0 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 OAP62690.1 - 1.9e-07 30.9 0.5 2.7e-07 30.3 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 OAP62690.1 - 2.5e-05 23.4 0.2 3.8e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 OAP62690.1 - 3.3e-05 22.7 0.2 5.1e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP62690.1 - 0.00034 20.6 0.7 0.00099 19.1 0.3 1.8 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAP62690.1 - 0.017 13.9 0.1 0.029 13.2 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 OAP62690.1 - 0.028 14.3 0.1 0.046 13.7 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 OAP62690.1 - 0.03 14.7 0.2 0.058 13.8 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 OAP62690.1 - 0.048 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 OAP62690.1 - 0.076 11.8 0.5 0.15 10.9 0.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_25 PF13649.1 OAP62690.1 - 0.094 13.0 0.0 0.36 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_3 PF13738.1 OAP62691.1 - 1.2e-26 94.0 0.0 2e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP62691.1 - 2.1e-11 42.7 0.0 8.6e-11 40.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP62691.1 - 4.3e-08 33.2 0.0 1.2e-06 28.5 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP62691.1 - 1.6e-07 31.2 0.0 1.1e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP62691.1 - 4.8e-05 22.4 0.0 0.0023 16.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP62691.1 - 0.0001 22.0 4.1 0.0013 18.5 0.1 3.3 3 1 1 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAP62691.1 - 0.00046 19.2 0.0 0.0011 18.0 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 OAP62691.1 - 0.0012 17.8 0.4 0.01 14.7 0.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 OAP62691.1 - 0.0056 15.8 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP62691.1 - 0.03 14.5 0.1 5 7.4 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 OAP62691.1 - 0.035 12.9 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 OAP62691.1 - 0.097 11.7 0.1 5.3 5.9 0.2 2.2 1 1 1 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 OAP62691.1 - 0.12 12.8 0.2 14 6.1 0.3 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Rick_17kDa_Anti PF05433.10 OAP62692.1 - 0.013 15.1 8.6 0.033 13.8 6.0 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF456 PF04306.8 OAP62692.1 - 0.1 12.6 0.4 0.13 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF533 PF04391.7 OAP62692.1 - 4.4 6.6 10.9 1.1 8.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Amidase PF01425.16 OAP62693.1 - 1.3e-97 327.4 0.0 1.6e-97 327.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Citrate_synt PF00285.16 OAP62694.1 - 9.6e-19 67.3 0.0 1e-15 57.3 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 OAP62694.1 - 5.9e-18 65.1 0.0 1.3e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 OAP62694.1 - 6.6e-16 58.2 0.0 1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 OAP62694.1 - 5.5e-05 22.7 0.0 0.00023 20.7 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 OAP62695.1 - 3.2e-07 29.9 0.0 4.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain DNA_pol_delta_4 PF04081.8 OAP62696.1 - 1.7e-26 92.8 7.2 1.2e-25 90.1 5.0 2.1 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 GAGA_bind PF06217.7 OAP62696.1 - 0.59 10.0 4.6 0.74 9.7 3.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 OAP62696.1 - 2.7 7.8 14.9 3.5 7.4 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.5 OAP62696.1 - 3.2 6.8 20.0 4 6.5 13.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pkinase PF00069.20 OAP62697.1 - 1.7e-49 168.2 0.0 2.5e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP62697.1 - 4.9e-23 81.5 0.0 6.3e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 OAP62697.1 - 0.00074 19.5 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 OAP62697.1 - 0.017 14.1 0.1 1.2 8.0 0.0 2.5 1 1 0 2 2 2 0 Kinase-like APH PF01636.18 OAP62697.1 - 0.12 12.1 0.1 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1877 PF08974.5 OAP62697.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) RIO1 PF01163.17 OAP62697.1 - 0.3 10.3 1.3 0.73 9.1 0.9 1.5 1 1 0 1 1 1 0 RIO1 family Voltage_CLC PF00654.15 OAP62699.1 - 6e-91 305.1 22.8 6e-91 305.1 15.8 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 OAP62699.1 - 4.6e-11 42.3 0.1 9.9e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 OAP62700.1 - 1.3e-12 47.6 0.6 1.5e-11 44.1 0.6 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAP62700.1 - 0.0009 19.3 0.4 0.0014 18.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 OAP62700.1 - 0.04 13.7 0.1 0.061 13.1 0.1 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Pkinase PF00069.20 OAP62701.1 - 6.4e-18 64.8 0.0 1.2e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP62701.1 - 0.012 14.7 0.0 0.032 13.2 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1490 PF07371.7 OAP62701.1 - 0.12 12.2 0.1 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) CorA PF01544.13 OAP62702.1 - 2.7e-07 29.9 1.7 4.5e-07 29.1 1.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Methyltransf_23 PF13489.1 OAP62705.1 - 1.1e-20 73.9 0.0 1.6e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP62705.1 - 2.2e-18 66.5 0.0 3.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP62705.1 - 1.2e-17 63.8 0.0 1.7e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP62705.1 - 3.1e-16 59.9 0.0 5.3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAP62705.1 - 1.5e-14 53.7 0.0 2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 OAP62705.1 - 5.2e-14 52.5 0.0 8.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP62705.1 - 2.1e-13 50.3 0.1 4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP62705.1 - 3.2e-10 40.2 0.0 5.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP62705.1 - 1.1e-09 37.7 0.0 4e-08 32.6 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAP62705.1 - 8.1e-08 31.8 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 OAP62705.1 - 2.8e-07 30.2 0.0 3.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 OAP62705.1 - 1.2e-05 24.8 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.6 OAP62705.1 - 1.9e-05 24.2 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.6 OAP62705.1 - 2.5e-05 23.1 0.0 3.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 OAP62705.1 - 4.8e-05 22.6 0.0 7.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 OAP62705.1 - 0.00018 21.1 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 OAP62705.1 - 0.00025 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 OAP62705.1 - 0.00042 19.9 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 OAP62705.1 - 0.0005 19.1 0.0 0.0011 18.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 OAP62705.1 - 0.0026 17.4 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAP62705.1 - 0.0067 17.2 0.0 0.013 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 OAP62705.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB N2227 PF07942.7 OAP62705.1 - 0.015 14.2 0.0 2.3 7.1 0.0 2.1 1 1 1 2 2 2 0 N2227-like protein DUF633 PF04816.7 OAP62705.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF633) RrnaAD PF00398.15 OAP62705.1 - 0.025 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_S5_C PF03719.10 OAP62705.1 - 0.056 12.7 0.0 11 5.3 0.0 3.0 3 1 0 3 3 2 0 Ribosomal protein S5, C-terminal domain GCD14 PF08704.5 OAP62705.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_16 PF10294.4 OAP62705.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UCR_TM PF02921.9 OAP62706.1 - 2.2e-19 69.4 0.4 4.6e-19 68.4 0.3 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 OAP62706.1 - 1.1e-17 63.3 0.0 1.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain She9_MDM33 PF05546.6 OAP62707.1 - 2.8e-90 301.4 4.2 6.4e-90 300.2 2.9 1.6 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 OAP62707.1 - 0.011 15.3 0.8 0.011 15.3 0.6 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein TBCA PF02970.11 OAP62707.1 - 0.31 11.1 0.1 0.31 11.1 0.0 2.8 3 0 0 3 3 3 0 Tubulin binding cofactor A CENP-Q PF13094.1 OAP62707.1 - 5.3 7.0 9.2 0.43 10.5 1.4 2.7 4 0 0 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit HAD PF12710.2 OAP62708.1 - 2.7e-09 37.4 0.0 4.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAP62708.1 - 0.0001 22.5 0.0 0.001 19.3 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 OAP62708.1 - 0.00035 19.8 0.1 0.003 16.7 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 OAP62708.1 - 0.0016 17.7 0.0 0.0041 16.4 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) p450 PF00067.17 OAP62709.1 - 1.2e-68 231.7 0.0 1.5e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YiiD_Cterm PF09500.5 OAP62709.1 - 0.15 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) GFA PF04828.9 OAP62710.1 - 1e-15 57.4 0.9 1.6e-15 56.8 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 OAP62710.1 - 0.0016 18.1 0.2 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 Nudix N-terminal adh_short PF00106.20 OAP62711.1 - 5.2e-14 52.5 0.0 4.1e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62711.1 - 3.1e-07 30.2 0.0 6.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP62711.1 - 1.6e-05 24.5 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAP62711.1 - 0.00022 21.0 0.0 0.0057 16.4 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAP62711.1 - 0.0022 18.0 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding G-patch PF01585.18 OAP62712.1 - 1.3e-08 34.4 0.0 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 G-patch domain PRCC PF10253.4 OAP62712.1 - 0.11 13.2 2.9 0.2 12.3 2.0 1.4 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting OB_RNB PF08206.6 OAP62712.1 - 0.5 9.8 1.9 3.1 7.3 0.2 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Sec1 PF00995.18 OAP62713.1 - 1.2e-128 430.2 0.0 1.4e-128 430.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SUV3_C PF12513.3 OAP62714.1 - 1.4e-16 59.6 2.2 2.9e-16 58.6 1.5 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 OAP62714.1 - 2.9e-09 36.6 0.0 6.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.13 OAP62714.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase HA2 PF04408.18 OAP62716.1 - 8.5e-29 99.5 0.1 2.9e-28 97.8 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAP62716.1 - 6.9e-26 90.3 0.0 1.8e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAP62716.1 - 4.4e-12 45.6 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 OAP62716.1 - 6.9e-09 35.6 0.2 1.5e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 OAP62716.1 - 2.5e-06 27.1 0.1 5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAP62716.1 - 0.00012 22.1 0.0 0.00032 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAP62716.1 - 0.00013 20.9 0.0 0.00042 19.3 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 OAP62716.1 - 0.00082 19.0 0.4 0.011 15.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 OAP62716.1 - 0.0047 16.6 0.2 0.013 15.2 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAP62716.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 OAP62716.1 - 3.4 7.9 6.6 1.9 8.8 0.1 3.4 3 1 1 4 4 4 0 ABC transporter SlyX PF04102.7 OAP62717.1 - 1.4 9.3 6.9 0.27 11.6 1.9 2.0 2 0 0 2 2 2 0 SlyX Aldo_ket_red PF00248.16 OAP62718.1 - 7.7e-51 172.5 0.0 9.3e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Catalase PF00199.14 OAP62719.1 - 5.2e-169 561.9 0.1 6.5e-169 561.6 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAP62719.1 - 5.3e-15 55.0 0.1 1.3e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 Catalase-related immune-responsive SGT1 PF07093.6 OAP62720.1 - 0.15 10.4 11.9 0.18 10.1 8.2 1.2 1 0 0 1 1 1 0 SGT1 protein PLA2_B PF01735.13 OAP62721.1 - 6.2e-77 258.8 0.7 3.8e-76 256.2 0.5 2.0 1 1 0 1 1 1 1 Lysophospholipase catalytic domain PLAC8 PF04749.12 OAP62722.1 - 1.1e-18 67.7 9.0 1.5e-18 67.2 6.3 1.2 1 0 0 1 1 1 1 PLAC8 family Ank_2 PF12796.2 OAP62723.1 - 8.8e-17 61.2 0.2 1.9e-08 34.5 0.0 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAP62723.1 - 4.2e-15 54.6 9.2 6.9e-06 25.6 0.1 5.1 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 OAP62723.1 - 6.4e-13 48.8 0.8 2.7e-06 27.7 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP62723.1 - 4e-10 38.9 1.8 0.0025 17.8 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAP62723.1 - 1.2e-09 38.1 0.8 6.4e-05 23.0 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.7 OAP62723.1 - 2.9e-09 36.7 0.1 8.3e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain RVP PF00077.15 OAP62723.1 - 0.002 18.0 0.3 6.9 6.6 0.0 3.5 2 1 0 2 2 2 1 Retroviral aspartyl protease AAA_22 PF13401.1 OAP62723.1 - 0.013 15.6 0.0 0.053 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.13 OAP62724.1 - 9.1e-29 100.1 17.6 1.8e-28 99.2 12.2 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1680 PF07944.7 OAP62724.1 - 2e-16 59.3 0.0 1.1e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Peptidase_S26 PF10502.4 OAP62725.1 - 5.1e-08 32.5 0.0 5.5e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 OAP62725.1 - 0.00012 21.6 0.1 0.0003 20.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase S24-like PBP PF01161.15 OAP62726.1 - 4.1e-12 46.1 0.0 6.3e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3761 PF12587.3 OAP62726.1 - 0.039 14.0 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) DUF2422 PF10337.4 OAP62727.1 - 1.1e-68 232.0 4.1 9e-68 229.1 0.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 OAP62727.1 - 6.9e-14 51.8 14.4 6.9e-14 51.8 10.0 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 OAP62727.1 - 6.1e-11 42.3 0.6 1.2e-10 41.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) Med2 PF11214.3 OAP62728.1 - 5.6e-07 29.5 1.4 1.2e-06 28.4 1.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 PAT1 PF09770.4 OAP62728.1 - 1 7.5 22.8 1.4 7.0 15.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.17 OAP62729.1 - 6.4e-59 195.5 0.0 5.4e-21 74.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP62729.1 - 5.3e-42 141.6 0.0 1.2e-13 50.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP62729.1 - 2.6e-29 100.8 0.0 8.5e-10 38.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAP62729.1 - 1.9e-07 30.7 0.0 0.0084 15.8 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Myosin_tail_1 PF01576.14 OAP62731.1 - 0.00022 19.1 6.3 0.00022 19.1 4.4 1.4 2 0 0 2 2 2 1 Myosin tail DUF972 PF06156.8 OAP62731.1 - 0.0032 17.7 2.4 0.011 16.1 1.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF972) AAA_16 PF13191.1 OAP62731.1 - 0.0077 16.2 1.1 0.028 14.4 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF2951 PF11166.3 OAP62731.1 - 0.18 11.6 4.8 0.55 10.1 3.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Fez1 PF06818.10 OAP62731.1 - 0.58 10.1 9.1 0.16 12.0 3.0 2.2 2 0 0 2 2 2 0 Fez1 AAA PF00004.24 OAP62732.1 - 5.1e-14 52.5 0.1 1.7e-13 50.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP62732.1 - 0.00015 21.9 0.4 0.0062 16.6 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAP62732.1 - 0.00015 21.4 0.0 0.00037 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAP62732.1 - 0.00062 19.4 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 OAP62732.1 - 0.0012 19.7 0.5 0.0035 18.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 OAP62732.1 - 0.0013 18.8 0.0 0.0034 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 OAP62732.1 - 0.0023 17.8 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAP62732.1 - 0.0026 18.0 3.7 0.0042 17.4 0.2 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAP62732.1 - 0.0032 16.5 0.5 0.026 13.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAP62732.1 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Staphylokinase PF02821.11 OAP62732.1 - 0.0058 16.4 1.7 0.072 12.8 0.4 2.7 2 1 0 2 2 2 1 Staphylokinase/Streptokinase family AAA_11 PF13086.1 OAP62732.1 - 0.0081 15.7 0.4 0.015 14.9 0.2 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAP62732.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 OAP62732.1 - 0.016 15.2 0.3 0.047 13.7 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain ArgK PF03308.11 OAP62732.1 - 0.017 13.9 0.2 0.031 13.0 0.1 1.4 1 0 0 1 1 1 0 ArgK protein Sigma54_activat PF00158.21 OAP62732.1 - 0.033 13.6 0.1 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.10 OAP62732.1 - 0.035 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Torsin PF06309.6 OAP62732.1 - 0.042 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.1 OAP62732.1 - 0.057 13.0 0.2 0.18 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 OAP62732.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAP62732.1 - 0.065 13.4 0.1 0.21 11.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.7 OAP62732.1 - 0.078 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 OAP62732.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 OAP62732.1 - 0.11 12.3 1.2 0.38 10.6 0.0 2.3 3 0 0 3 3 2 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 OAP62733.1 - 3.4e-13 49.6 1.7 2.6e-11 43.4 0.5 3.1 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 OAP62733.1 - 3e-08 33.8 0.0 7.1e-06 26.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 OAP62733.1 - 5.6e-05 23.2 4.5 0.025 14.5 0.0 4.3 3 2 2 5 5 5 1 AAA ATPase domain AAA_10 PF12846.2 OAP62733.1 - 0.001 18.5 0.0 0.019 14.4 0.0 2.8 2 1 0 3 3 3 1 AAA-like domain AAA_17 PF13207.1 OAP62733.1 - 0.0047 17.7 0.1 0.03 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 OAP62733.1 - 0.0071 16.5 0.0 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 OAP62733.1 - 0.0074 16.5 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 OAP62733.1 - 0.01 16.2 0.2 0.058 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAP62733.1 - 0.01 15.3 0.1 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 OAP62733.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAP62733.1 - 0.022 14.4 0.0 0.81 9.3 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 OAP62733.1 - 0.042 13.5 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA PF00004.24 OAP62733.1 - 0.066 13.4 0.0 6.7 6.9 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 OAP62733.1 - 0.12 11.5 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 OAP62733.1 - 0.13 12.7 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein CMD PF02627.15 OAP62734.1 - 1.5e-12 47.1 6.6 2.3e-09 36.9 2.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Dioxygenase_C PF00775.16 OAP62735.1 - 2.3e-48 163.8 0.0 3.1e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 OAP62735.1 - 4.2e-12 45.8 0.0 7.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 OAP62735.1 - 0.0013 18.7 0.3 0.068 13.2 0.0 2.7 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Lactonase PF10282.4 OAP62736.1 - 6.5e-18 64.9 0.0 1.1e-17 64.1 0.0 1.4 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.15 OAP62736.1 - 0.063 13.2 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Arylesterase DUF4394 PF14339.1 OAP62736.1 - 0.12 11.5 0.0 0.28 10.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4394) Abhydrolase_6 PF12697.2 OAP62737.1 - 7.2e-23 81.6 1.1 1.3e-22 80.7 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62737.1 - 3e-09 36.7 0.0 5e-08 32.7 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP62737.1 - 1.3e-07 31.5 0.1 4e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAP62737.1 - 0.0095 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Putative esterase PIF1 PF05970.9 OAP62738.1 - 4.7e-62 210.0 1.5 9.8e-47 159.6 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 OAP62738.1 - 4.8e-17 62.1 0.0 9.4e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAP62738.1 - 2.1e-07 31.1 0.0 6.4e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP62738.1 - 5.4e-05 22.8 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 OAP62738.1 - 7.9e-05 22.7 0.0 0.00038 20.5 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 OAP62738.1 - 0.00092 18.4 0.0 0.0035 16.6 0.0 1.9 1 0 0 1 1 1 1 PhoH-like protein Herpes_Helicase PF02689.9 OAP62738.1 - 0.00095 17.0 0.1 0.0029 15.4 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA PF00004.24 OAP62738.1 - 0.0019 18.4 0.0 0.0056 16.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAP62738.1 - 0.003 17.5 0.0 0.012 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 OAP62738.1 - 0.0038 17.1 0.0 0.016 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAP62738.1 - 0.004 16.5 0.0 0.0097 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAP62738.1 - 0.0052 15.7 0.0 0.0099 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 OAP62738.1 - 0.0086 15.0 0.1 0.028 13.3 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 OAP62738.1 - 0.0088 16.3 0.1 0.031 14.5 0.1 2.1 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 OAP62738.1 - 0.0093 15.6 0.0 0.034 13.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 OAP62738.1 - 0.012 15.1 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 OAP62738.1 - 0.016 15.4 0.0 0.05 13.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase UvrD-helicase PF00580.16 OAP62738.1 - 0.028 13.7 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.2 OAP62738.1 - 0.044 12.8 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 DUF258 PF03193.11 OAP62738.1 - 0.05 12.7 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 OAP62738.1 - 0.061 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 OAP62738.1 - 0.067 12.7 0.9 1.1 8.7 0.0 3.0 2 1 0 3 3 3 0 AAA domain MobB PF03205.9 OAP62738.1 - 0.093 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B YjeF_N PF03853.10 OAP62739.1 - 1.3e-32 112.7 0.0 1.9e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 OAP62739.1 - 3.9e-11 43.3 0.5 8.5e-11 42.3 0.4 1.5 1 0 0 1 1 1 1 FDF domain Amidoligase_2 PF12224.3 OAP62741.1 - 6e-13 48.9 0.0 8.1e-12 45.2 0.0 2.7 1 1 0 1 1 1 1 Putative amidoligase enzyme Pro_isomerase PF00160.16 OAP62742.1 - 4.8e-42 143.7 0.0 1e-41 142.7 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 OAP62742.1 - 1.4e-05 24.4 0.8 1.4e-05 24.4 0.5 2.5 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 OAP62742.1 - 1.5e-05 24.8 0.0 5.7e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 U-box domain PGA2 PF07543.7 OAP62742.1 - 0.0039 16.9 3.7 0.018 14.8 0.1 2.5 2 0 0 2 2 2 1 Protein trafficking PGA2 ATP_transf PF09830.4 OAP62743.1 - 1.2e-13 50.6 0.0 3.9e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 ATP adenylyltransferase HIT PF01230.18 OAP62743.1 - 0.14 12.7 0.1 0.58 10.7 0.1 2.1 1 1 0 1 1 1 0 HIT domain GTP_EFTU PF00009.22 OAP62744.1 - 3e-61 206.1 0.1 4.1e-61 205.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAP62744.1 - 9.8e-24 83.4 0.2 6e-23 80.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAP62744.1 - 1.1e-16 60.7 2.8 2.5e-16 59.5 1.9 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAP62744.1 - 9.1e-05 22.3 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 OAP62744.1 - 0.00011 21.8 1.3 0.00024 20.6 0.9 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 OAP62744.1 - 0.025 15.0 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 OAP62744.1 - 0.026 14.0 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 OAP62744.1 - 0.1 12.0 0.2 0.91 8.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain adh_short PF00106.20 OAP62745.1 - 0.036 13.9 0.9 0.15 11.9 0.3 1.9 1 1 1 2 2 2 0 short chain dehydrogenase Bac_luciferase PF00296.15 OAP62746.1 - 2.4e-60 204.2 0.2 3.3e-60 203.7 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pyr_redox_3 PF13738.1 OAP62747.1 - 4.4e-22 79.1 0.0 1.2e-21 77.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP62747.1 - 2.7e-11 43.3 0.0 1.3e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP62747.1 - 5.3e-09 35.4 0.0 2.1e-06 26.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 OAP62747.1 - 5.2e-07 28.2 0.1 6.6e-06 24.5 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP62747.1 - 2.3e-06 27.6 0.0 0.00016 21.6 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP62747.1 - 0.00026 20.8 0.2 0.016 14.9 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 OAP62747.1 - 0.00065 18.7 0.0 0.036 12.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase MFS_1 PF07690.11 OAP62748.1 - 3.8e-25 88.3 35.9 3.8e-25 88.3 24.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2046 PF09755.4 OAP62749.1 - 0.0035 16.2 1.0 0.0039 16.1 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Tropomyosin_1 PF12718.2 OAP62749.1 - 0.0095 15.7 1.1 0.013 15.3 0.7 1.2 1 0 0 1 1 1 1 Tropomyosin like Afi1 PF07792.7 OAP62749.1 - 0.12 12.3 0.2 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PAD_porph PF04371.10 OAP62750.1 - 1.4e-85 287.2 0.0 1.6e-85 287.1 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.12 OAP62750.1 - 0.15 11.0 0.1 0.31 10.0 0.0 1.6 2 0 0 2 2 2 0 Amidinotransferase Amidase PF01425.16 OAP62751.1 - 1.6e-48 165.6 0.1 8.6e-48 163.2 0.0 1.9 1 1 0 1 1 1 1 Amidase DUF3055 PF11256.3 OAP62752.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3055) Lip_prot_lig_C PF10437.4 OAP62753.1 - 0.068 12.8 0.0 4.2 7.1 0.0 2.1 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus TPR_12 PF13424.1 OAP62754.1 - 1.3e-35 121.1 22.0 2.9e-11 43.1 0.0 5.3 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAP62754.1 - 4.9e-28 96.2 17.9 8.9e-05 22.2 0.5 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat NB-ARC PF00931.17 OAP62754.1 - 4.3e-16 58.6 0.1 1.4e-15 56.9 0.0 1.9 3 0 0 3 3 3 1 NB-ARC domain TPR_11 PF13414.1 OAP62754.1 - 7.2e-12 44.7 7.8 4.5e-05 23.0 0.1 4.4 2 1 3 5 5 5 4 TPR repeat TPR_4 PF07721.9 OAP62754.1 - 2e-11 43.1 26.3 0.11 12.9 1.2 8.5 9 0 0 9 9 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 OAP62754.1 - 4.4e-11 41.8 11.7 0.0036 17.1 0.1 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP62754.1 - 1.5e-10 40.0 14.6 0.14 12.0 0.2 7.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAP62754.1 - 2.5e-10 39.4 0.7 0.033 13.8 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP62754.1 - 7.3e-09 35.8 15.6 0.0014 18.9 1.4 6.1 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAP62754.1 - 8e-08 32.7 18.9 0.0019 18.8 0.3 6.5 4 3 1 6 6 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 OAP62754.1 - 2.1e-07 31.1 0.3 8e-06 26.0 0.0 3.6 3 1 1 4 4 4 1 AAA domain DUF676 PF05057.9 OAP62754.1 - 3.4e-06 26.5 0.0 5e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 Putative serine esterase (DUF676) Apc3 PF12895.2 OAP62754.1 - 6.9e-06 26.1 4.8 0.013 15.6 2.0 4.4 1 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 OAP62754.1 - 1.6e-05 25.1 29.0 0.032 14.8 0.3 8.7 5 2 4 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAP62754.1 - 4.4e-05 23.3 6.3 8.5 6.8 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAP62754.1 - 0.00011 22.2 7.2 0.26 11.4 0.1 5.1 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAP62754.1 - 0.00013 21.4 6.1 7 6.6 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 OAP62754.1 - 0.00017 21.5 3.5 0.00039 20.3 0.7 2.5 1 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP62754.1 - 0.00079 19.0 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 OAP62754.1 - 0.0017 18.0 0.0 0.11 12.1 0.0 2.8 2 1 0 2 2 2 1 NACHT domain TPR_9 PF13371.1 OAP62754.1 - 0.0021 17.9 3.8 0.43 10.4 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat AAA_33 PF13671.1 OAP62754.1 - 0.0032 17.3 0.0 0.0097 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAP62754.1 - 0.0037 17.2 2.4 0.0045 16.9 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain Zeta_toxin PF06414.7 OAP62754.1 - 0.0056 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AA_kinase PF00696.23 OAP62754.1 - 0.022 14.3 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Amino acid kinase family TPR_21 PF09976.4 OAP62754.1 - 0.038 13.9 2.9 0.3 11.0 1.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Cutinase PF01083.17 OAP62754.1 - 0.075 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Cutinase Sas10_Utp3 PF04000.10 OAP62754.1 - 0.075 13.2 0.1 0.27 11.4 0.1 1.9 1 0 0 1 1 1 0 Sas10/Utp3/C1D family AAA PF00004.24 OAP62754.1 - 0.083 13.0 0.1 9 6.5 0.0 2.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_6 PF13174.1 OAP62754.1 - 0.14 12.6 13.2 45 4.8 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Tubulin PF00091.20 OAP62754.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Arch_ATPase PF01637.13 OAP62754.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase PIF1 PF05970.9 OAP62754.1 - 0.22 10.4 0.0 0.41 9.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase GFA PF04828.9 OAP62755.1 - 3.7e-13 49.2 3.0 1.3e-05 25.0 0.3 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF2197 PF09963.4 OAP62755.1 - 0.1 12.5 3.3 0.62 10.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Cys_rich_CWC PF14375.1 OAP62755.1 - 0.77 9.7 5.6 0.95 9.4 1.7 2.2 2 0 0 2 2 2 0 Cysteine-rich CWC HATPase_c PF02518.21 OAP62757.1 - 1e-25 89.6 0.0 1.9e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP62757.1 - 1.6e-24 86.0 0.1 3.4e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 OAP62757.1 - 9.4e-15 54.3 0.0 2.2e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 OAP62757.1 - 0.00046 20.3 1.7 0.26 11.4 0.0 3.3 3 0 0 3 3 3 2 HAMP domain Myc_target_1 PF15179.1 OAP62757.1 - 0.16 11.5 3.2 0.36 10.4 2.2 1.5 1 0 0 1 1 1 0 Myc target protein 1 COMPASS-Shg1 PF05205.7 OAP62758.1 - 6.2e-29 100.4 1.7 1e-27 96.5 0.1 2.7 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.13 OAP62759.1 - 3.1e-23 82.0 0.1 4.1e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HNH_2 PF13391.1 OAP62760.1 - 0.00041 20.0 0.0 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease Catalase PF00199.14 OAP62761.1 - 1e-144 481.9 0.3 1e-144 481.9 0.2 1.4 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.7 OAP62761.1 - 4.9e-14 51.9 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive NAD_binding_10 PF13460.1 OAP62762.1 - 5.7e-08 32.9 0.0 9.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP62762.1 - 2.8e-07 30.0 0.0 6.4e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 OAP62762.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribonucleas_3_3 PF14622.1 OAP62763.1 - 4.9e-08 32.9 0.0 6.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 OAP62763.1 - 1.6e-05 25.3 0.3 4.7e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Ribonuclease III domain DUF4543 PF15076.1 OAP62764.1 - 0.011 15.7 0.1 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) B PF02216.11 OAP62764.1 - 0.071 12.8 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 B domain AAA PF00004.24 OAP62765.1 - 9.3e-43 145.5 0.7 2.9e-15 56.6 0.0 5.7 6 0 0 6 6 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 OAP62765.1 - 5.2e-35 120.6 0.0 1.5e-34 119.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAP62765.1 - 9e-28 97.4 17.4 8.9e-22 77.8 0.0 6.5 4 2 0 5 5 4 2 AAA domain AAA_19 PF13245.1 OAP62765.1 - 4.5e-22 77.5 1.4 7e-06 25.7 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_22 PF13401.1 OAP62765.1 - 1.6e-18 67.0 0.5 2.5e-06 27.6 0.0 6.7 4 3 0 4 4 4 3 AAA domain AAA_17 PF13207.1 OAP62765.1 - 5.1e-16 59.5 8.6 6.8e-05 23.6 0.0 6.2 5 0 0 5 5 5 4 AAA domain AAA_5 PF07728.9 OAP62765.1 - 8.2e-15 54.7 1.3 0.023 14.4 0.0 5.2 5 0 0 5 5 5 4 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 OAP62765.1 - 5.3e-12 45.7 0.3 0.031 13.7 0.0 5.7 6 0 0 6 6 6 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 OAP62765.1 - 6.8e-10 38.8 15.8 0.015 14.9 0.0 6.4 6 0 0 6 6 5 4 AAA domain Mg_chelatase PF01078.16 OAP62765.1 - 4.7e-09 35.7 0.2 0.31 10.1 0.0 4.8 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 OAP62765.1 - 6.1e-09 36.0 0.4 0.36 11.0 0.0 4.6 4 0 0 4 4 4 2 RNA helicase AAA_18 PF13238.1 OAP62765.1 - 1.7e-08 34.8 10.5 0.037 14.3 0.0 5.9 5 1 0 5 5 5 2 AAA domain RuvB_N PF05496.7 OAP62765.1 - 7.6e-08 31.6 0.1 0.086 11.8 0.0 4.6 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 OAP62765.1 - 3.5e-07 30.2 9.6 0.087 12.7 0.0 5.6 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.1 OAP62765.1 - 1e-06 28.6 0.0 0.23 11.3 0.0 4.5 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 OAP62765.1 - 1.6e-06 27.6 0.4 3.1 7.1 0.0 4.6 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_28 PF13521.1 OAP62765.1 - 6.2e-06 26.2 2.7 0.26 11.2 0.0 4.8 4 0 0 4 4 4 1 AAA domain Torsin PF06309.6 OAP62765.1 - 2.1e-05 24.3 0.2 7.6 6.4 0.0 4.4 4 0 0 4 4 4 0 Torsin PhoH PF02562.11 OAP62765.1 - 2.6e-05 23.5 1.9 0.73 9.0 0.0 4.5 5 0 0 5 5 5 2 PhoH-like protein KaiC PF06745.8 OAP62765.1 - 4.5e-05 22.6 1.0 0.92 8.5 0.0 4.3 4 0 0 4 4 4 1 KaiC AAA_25 PF13481.1 OAP62765.1 - 5e-05 22.7 2.1 1.1 8.6 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.1 OAP62765.1 - 0.00015 21.4 4.0 0.84 9.1 0.2 4.4 4 0 0 4 4 4 1 AAA domain DUF2075 PF09848.4 OAP62765.1 - 0.00052 19.0 14.1 0.033 13.1 0.0 6.1 6 1 0 6 6 5 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 OAP62765.1 - 0.00057 19.9 24.2 0.33 10.8 0.0 6.5 7 0 0 7 7 6 3 AAA ATPase domain MobB PF03205.9 OAP62765.1 - 0.001 18.8 1.4 12 5.6 0.0 4.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAP62765.1 - 0.011 15.3 1.3 14 5.2 0.0 4.3 4 0 0 4 4 4 0 NACHT domain SRP54 PF00448.17 OAP62765.1 - 0.049 13.0 2.1 8.6 5.7 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 OAP62765.1 - 0.067 12.8 5.3 5.6 6.6 0.0 4.1 4 0 0 4 4 4 0 NTPase 6PF2K PF01591.13 OAP62765.1 - 0.067 12.2 0.5 0.38 9.7 0.0 2.4 3 0 0 3 3 3 0 6-phosphofructo-2-kinase SKI PF01202.17 OAP62765.1 - 0.85 9.4 15.7 5 6.9 0.0 5.9 5 0 0 5 5 4 0 Shikimate kinase Piwi PF02171.12 OAP62766.1 - 1.1e-73 247.9 0.0 1.5e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 OAP62766.1 - 5.3e-15 54.9 0.0 1.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 OAP62766.1 - 9e-11 40.9 0.0 2.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Ribonuclease_3 PF00636.21 OAP62767.1 - 1.4e-44 151.2 0.0 1.1e-21 77.4 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAP62767.1 - 5.1e-32 110.5 0.0 1.5e-16 60.5 0.0 3.7 2 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 OAP62767.1 - 7.9e-21 73.6 0.1 3e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 OAP62767.1 - 4e-18 65.0 0.0 1.2e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP62767.1 - 5.5e-10 38.9 0.0 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAP62767.1 - 0.002 18.0 0.0 0.0048 16.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 OAP62769.1 - 0.0016 18.0 2.2 0.0016 18.0 1.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP62769.1 - 0.0086 15.7 4.8 0.0086 15.7 3.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 OAP62769.1 - 0.0094 15.8 12.1 0.012 15.4 0.6 2.6 2 1 0 2 2 2 1 IBR domain zf-RING_UBOX PF13445.1 OAP62769.1 - 0.026 14.2 0.3 0.063 13.0 0.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Motilin_ghrelin PF04644.7 OAP62769.1 - 0.12 12.1 0.8 0.2 11.4 0.6 1.4 1 0 0 1 1 1 0 Motilin/ghrelin zf-RING_5 PF14634.1 OAP62769.1 - 0.32 10.7 12.4 0.031 14.0 4.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 OAP62769.1 - 0.44 10.4 11.9 0.05 13.4 3.8 2.3 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 OAP62769.1 - 0.58 10.3 3.5 0.42 10.7 0.8 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 OAP62769.1 - 0.69 9.9 12.7 0.04 13.9 3.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPRTase PF14681.1 OAP62770.1 - 1.4e-32 112.6 1.0 2.6e-32 111.7 0.7 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.2 OAP62770.1 - 6.1e-08 33.0 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP62770.1 - 2.5e-06 28.0 0.2 6.1e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 OAP62770.1 - 8.5e-06 26.5 0.0 3.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAP62770.1 - 1.5e-05 24.9 0.2 4.9e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Pribosyltran PF00156.22 OAP62770.1 - 0.00027 20.6 2.3 0.029 14.0 1.3 3.1 2 1 0 2 2 2 1 Phosphoribosyl transferase domain AAA_18 PF13238.1 OAP62770.1 - 0.0007 19.8 0.1 0.0022 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 OAP62770.1 - 0.0051 15.8 0.0 0.0088 15.0 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 OAP62770.1 - 0.0077 16.2 1.4 0.027 14.4 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain PRTase_2 PF15609.1 OAP62770.1 - 0.015 14.6 0.6 0.036 13.3 0.4 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase AAA_23 PF13476.1 OAP62770.1 - 0.018 15.3 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 OAP62770.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TPP_enzyme_M PF00205.17 OAP62770.1 - 0.055 13.2 0.8 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain AAA_30 PF13604.1 OAP62770.1 - 0.11 12.1 2.9 0.2 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.1 OAP62770.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CYTH PF01928.16 OAP62771.1 - 5.1e-11 42.5 0.0 7.6e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 CYTH domain Reg_prop PF07494.6 OAP62771.1 - 0.079 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Two component regulator propeller FAD_binding_3 PF01494.14 OAP62772.1 - 6.4e-23 81.3 0.1 3.4e-22 78.9 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP62772.1 - 6.4e-09 35.1 2.4 1.9e-07 30.3 1.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP62772.1 - 7.9e-07 29.0 0.7 2.2e-06 27.5 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP62772.1 - 3e-05 23.9 0.6 0.00013 21.8 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP62772.1 - 5e-05 23.6 0.5 0.00014 22.2 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP62772.1 - 0.0001 21.3 2.9 0.00017 20.5 2.0 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 OAP62772.1 - 0.0013 18.3 0.5 0.0062 16.1 0.3 2.1 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 OAP62772.1 - 0.0021 16.6 0.1 0.0031 16.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 OAP62772.1 - 0.0021 16.7 2.4 0.33 9.5 0.7 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.17 OAP62772.1 - 0.0034 16.3 0.2 0.0043 15.9 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 OAP62772.1 - 0.0058 16.4 0.3 0.21 11.3 0.2 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAP62772.1 - 0.0098 15.0 0.4 0.014 14.4 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 OAP62772.1 - 0.017 14.2 0.3 0.026 13.6 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 OAP62772.1 - 0.03 13.9 1.0 0.053 13.1 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 OAP62772.1 - 0.041 13.8 0.2 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 OAP62772.1 - 0.056 13.7 0.4 0.23 11.7 0.3 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 OAP62772.1 - 0.12 11.6 0.2 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SE PF08491.5 OAP62772.1 - 0.22 10.3 0.0 1.1 8.0 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase DUF4598 PF15370.1 OAP62773.1 - 3.7e-15 56.1 4.3 3.7e-15 56.1 3.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4598) LpxB PF02684.10 OAP62773.1 - 0.036 12.6 0.1 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase SDA1 PF05285.7 OAP62773.1 - 4.2 6.5 27.5 1e+02 2.0 19.2 2.1 1 1 0 1 1 1 0 SDA1 DUF3827 PF12877.2 OAP62773.1 - 4.7 5.1 8.6 5.1 5.0 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ECIST_Cterm PF14784.1 OAP62773.1 - 7.2 6.5 7.1 0.76 9.7 1.8 1.7 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein RRN3 PF05327.6 OAP62773.1 - 7.3 4.5 12.4 9.6 4.1 8.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CytochromB561_N PF09786.4 OAP62773.1 - 7.7 4.8 8.7 9.3 4.5 6.0 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pkinase PF00069.20 OAP62774.1 - 2e-15 56.6 0.0 4.5e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP62774.1 - 2.8e-15 56.0 0.0 8.2e-15 54.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP62774.1 - 0.088 11.7 0.0 0.43 9.5 0.0 1.9 1 1 0 1 1 1 0 Kinase-like Kinesin PF00225.18 OAP62775.1 - 3.9e-114 380.8 0.0 6.8e-114 380.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF87 PF01935.12 OAP62775.1 - 0.1 12.4 8.4 0.57 9.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 HAD PF12710.2 OAP62776.1 - 7e-12 45.9 0.1 1e-11 45.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1593 PF07632.6 OAP62777.1 - 1.1e-92 310.0 0.0 1.5e-92 309.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 OAP62777.1 - 1.5e-06 26.8 0.0 2.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 REJ domain Sugar_tr PF00083.19 OAP62778.1 - 1.3e-63 215.1 23.9 1.5e-63 214.9 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62778.1 - 4.8e-16 58.4 30.2 4.9e-15 55.1 20.4 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP62778.1 - 1.1e-06 28.3 1.4 1.8e-06 27.6 0.2 2.0 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.1 OAP62778.1 - 0.0022 16.4 3.9 0.0022 16.4 2.7 3.4 2 2 2 4 4 4 2 MFS/sugar transport protein ADH_N PF08240.7 OAP62779.1 - 4.5e-28 97.1 2.5 7.7e-28 96.4 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP62779.1 - 2.9e-11 43.0 0.0 7.3e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 OAP62779.1 - 0.023 14.7 0.1 0.079 13.0 0.0 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.16 OAP62780.1 - 2.9e-50 170.6 0.0 3.4e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Transketolase_N PF00456.16 OAP62781.1 - 1.2e-119 398.9 0.0 1.7e-119 398.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 OAP62781.1 - 5.6e-42 143.2 0.1 1.1e-41 142.2 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 OAP62781.1 - 1e-07 31.1 0.0 4.7e-07 29.0 0.0 1.9 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 OAP62781.1 - 4.6e-07 29.8 0.0 1.2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 OAP62781.1 - 0.00046 19.7 0.4 0.0038 16.8 0.3 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PepSY_2 PF13670.1 OAP62781.1 - 0.032 14.1 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain E1_dh PF00676.15 OAP62781.1 - 0.037 12.7 0.0 0.066 11.9 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Peptidase_S41 PF03572.13 OAP62782.1 - 3.2e-12 46.2 0.0 6.3e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 ODV-E18 PF10717.4 OAP62783.1 - 0.085 12.3 0.1 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Fungal_trans PF04082.13 OAP62784.1 - 5.7e-25 87.6 0.0 8.9e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP62784.1 - 4e-08 33.0 12.3 1e-07 31.7 8.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP62785.1 - 7.7e-16 57.7 0.9 1.3e-15 57.0 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IF-2B PF01008.12 OAP62786.1 - 1.6e-68 230.7 0.0 2.3e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ribosomal_S14 PF00253.16 OAP62787.1 - 5.5e-17 60.8 3.5 7.3e-17 60.4 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 OAP62787.1 - 0.02 14.6 0.4 0.027 14.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.7 OAP62787.1 - 1.8 8.7 4.3 12 6.1 0.3 2.2 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Epimerase PF01370.16 OAP62788.1 - 3.2e-26 92.2 0.0 4.8e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP62788.1 - 2.7e-16 59.1 0.2 3.1e-15 55.6 0.2 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP62788.1 - 3.7e-11 43.3 0.0 1.8e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP62788.1 - 5.4e-10 38.6 0.0 5.3e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 OAP62788.1 - 2.5e-09 36.4 0.0 5e-09 35.4 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 OAP62788.1 - 7.1e-08 32.5 0.0 1.8e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAP62788.1 - 2.4e-05 23.4 0.0 0.00022 20.2 0.2 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 OAP62788.1 - 0.0045 16.6 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 OAP62788.1 - 0.026 13.7 0.1 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Apc13p PF05839.6 OAP62790.1 - 8.6e-17 60.9 0.0 1.3e-12 47.4 0.0 2.6 2 0 0 2 2 2 2 Apc13p protein FYDLN_acid PF09538.5 OAP62790.1 - 0.0069 16.9 1.8 0.015 15.8 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) TFIIA PF03153.8 OAP62790.1 - 0.074 12.9 4.4 0.029 14.2 1.4 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pol_alpha_B_N PF08418.5 OAP62791.1 - 1.4e-58 198.4 0.0 1.9e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 OAP62791.1 - 9.6e-33 113.1 0.0 1.5e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CBS PF00571.23 OAP62792.1 - 2.7e-21 75.0 6.5 2.2e-10 40.1 0.0 4.3 4 0 0 4 4 4 3 CBS domain PrpR_N PF06506.6 OAP62792.1 - 0.026 13.9 0.0 0.082 12.3 0.0 1.8 1 1 0 1 1 1 0 Propionate catabolism activator CRAL_TRIO PF00650.15 OAP62793.1 - 1.2e-37 128.8 0.0 1.9e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAP62793.1 - 8.2e-11 41.8 0.0 1.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAP62793.1 - 0.097 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Lipocalin_5 PF13924.1 OAP62794.1 - 1.3e-27 96.2 0.0 1.5e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Prp19_bind PF06991.6 OAP62795.1 - 5.9e-41 140.5 31.4 5.9e-41 140.5 21.7 2.1 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain TRAPP PF04051.11 OAP62796.1 - 6.4e-33 113.4 0.0 8.3e-33 113.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.16 OAP62797.1 - 1.2e-69 234.3 0.0 1.8e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase UCH PF00443.24 OAP62798.1 - 3.9e-38 131.1 0.0 6.3e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAP62798.1 - 1.2e-12 47.9 0.0 9.3e-12 44.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Las1 PF04031.8 OAP62799.1 - 1.8e-37 128.3 1.1 4.4e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Las1-like CDC45 PF02724.9 OAP62800.1 - 0.23 9.4 5.0 0.31 9.0 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein HCMVantigenic_N PF12154.3 OAP62800.1 - 0.43 10.5 8.8 2.6 8.0 3.8 2.6 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Nop14 PF04147.7 OAP62800.1 - 0.96 7.2 7.6 1.2 6.9 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family PAT1 PF09770.4 OAP62801.1 - 3.1e-251 836.0 15.4 1.4e-250 833.9 10.7 1.7 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 OAP62802.1 - 5e-143 475.9 2.7 6e-143 475.7 1.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 OAP62802.1 - 9.9 6.0 7.3 0.45 10.3 0.7 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Ribosom_S12_S23 PF00164.20 OAP62803.1 - 3.4e-39 133.0 1.2 4.8e-39 132.5 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acetyltransf_1 PF00583.19 OAP62804.1 - 4.2e-11 42.7 0.0 6.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP62804.1 - 2.2e-05 24.5 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP62804.1 - 3.4e-05 23.5 0.0 5.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAP62804.1 - 3.6e-05 23.8 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP62804.1 - 0.0015 18.4 0.0 0.0044 16.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 OAP62804.1 - 0.011 15.4 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF3749 PF12568.3 OAP62804.1 - 0.053 13.1 0.1 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.1 OAP62805.1 - 4.9e-36 124.7 0.0 5.7e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP62805.1 - 1.9e-32 112.5 0.2 2.3e-32 112.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62805.1 - 5e-14 52.3 0.1 7.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 OAP62805.1 - 3.9e-05 22.9 0.0 9.4e-05 21.6 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 OAP62805.1 - 0.00015 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.1 OAP62805.1 - 0.028 14.5 0.2 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain NAD_binding_7 PF13241.1 OAP62805.1 - 0.028 14.6 0.3 0.057 13.6 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 OAP62805.1 - 0.076 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Nup54 PF13874.1 OAP62807.1 - 0.013 15.2 1.0 0.042 13.5 0.0 2.2 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DcpS_C PF11969.3 OAP62808.1 - 2.6e-16 59.8 3.3 8.7e-16 58.2 2.3 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 OAP62808.1 - 5.4e-15 55.7 0.3 1.5e-14 54.3 0.2 1.7 1 1 0 1 1 1 1 HIT domain Nup160 PF11715.3 OAP62808.1 - 0.047 11.8 0.0 0.066 11.3 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ras PF00071.17 OAP62809.1 - 7e-60 201.0 0.1 8.2e-60 200.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP62809.1 - 1e-18 67.9 0.0 1.5e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP62809.1 - 5.7e-08 32.2 0.0 6.3e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAP62809.1 - 2.1e-07 30.5 0.1 1e-06 28.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAP62809.1 - 0.0032 17.3 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP62809.1 - 0.0044 16.2 0.0 0.0072 15.6 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.4 OAP62809.1 - 0.012 14.5 0.1 1.2 8.0 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 OAP62809.1 - 0.016 14.5 0.3 0.22 10.9 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 OAP62809.1 - 0.044 12.9 0.1 0.1 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MoCF_biosynth PF00994.19 OAP62810.1 - 1.2e-33 115.5 0.0 7.5e-33 112.9 0.0 2.0 2 0 0 2 2 2 1 Probable molybdopterin binding domain FAD_syn PF06574.7 OAP62810.1 - 0.1 12.1 0.0 5.6 6.5 0.0 2.1 2 0 0 2 2 2 0 FAD synthetase Cofilin_ADF PF00241.15 OAP62811.1 - 7.3e-09 35.5 0.0 8.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FAD_binding_3 PF01494.14 OAP62812.1 - 8.3e-72 242.1 0.0 1e-71 241.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 OAP62812.1 - 5.9e-36 123.6 0.0 9.1e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 OAP62812.1 - 0.0008 18.4 0.0 0.0025 16.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP62812.1 - 0.00097 19.4 0.0 0.032 14.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP62812.1 - 0.0058 15.5 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP62812.1 - 0.018 15.0 0.0 0.07 13.1 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP62812.1 - 0.022 13.2 0.0 0.048 12.1 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 OAP62812.1 - 0.022 14.6 0.1 0.059 13.2 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 OAP62812.1 - 0.024 14.0 0.1 0.057 12.8 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF3414 PF11894.3 OAP62814.1 - 0 1054.0 6.1 0 1053.7 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 OAP62815.1 - 1.2e-44 152.5 0.0 2.8e-44 151.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 OAP62815.1 - 4.4e-29 101.2 2.0 9.4e-28 96.9 0.0 2.9 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 OAP62815.1 - 2.1e-12 46.2 0.0 5.1e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 FATC domain DNA_pol_A PF00476.15 OAP62816.1 - 3.4e-101 338.6 0.0 4.5e-101 338.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 OAP62816.1 - 0.026 14.0 0.1 0.41 10.1 0.0 2.5 1 1 0 1 1 1 0 3'-5' exonuclease RIB43A PF05914.7 OAP62816.1 - 0.21 10.1 2.8 0.1 11.2 0.3 1.5 2 0 0 2 2 2 0 RIB43A DUF4604 PF15377.1 OAP62817.1 - 1.7e-21 77.0 12.3 2.1e-21 76.8 8.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Adaptin_binding PF10199.4 OAP62818.1 - 1.5e-12 47.9 7.8 1.7e-11 44.5 4.0 2.6 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 AATF-Che1 PF13339.1 OAP62818.1 - 1.5 9.0 4.9 11 6.2 0.1 3.2 3 1 0 3 3 3 0 Apoptosis antagonizing transcription factor LSM PF01423.17 OAP62819.1 - 3.9e-14 51.9 0.1 5.7e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAP62819.1 - 0.057 13.3 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.4 OAP62819.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 Phage tail tube protein PGP_phosphatase PF09419.5 OAP62820.1 - 1.3e-52 177.6 0.0 1.5e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 OAP62820.1 - 4.5e-07 29.4 0.0 7.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 OAP62820.1 - 0.02 15.1 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Turandot PF07240.6 OAP62822.1 - 0.0064 15.9 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Stress-inducible humoral factor Turandot Cullin_binding PF03556.10 OAP62824.1 - 1.2e-29 102.7 0.1 1.8e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Cullin binding vWA-TerF-like PF10138.4 OAP62825.1 - 7.1e-07 29.2 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 OAP62825.1 - 0.037 14.1 0.1 0.16 12.1 0.1 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain DnaG_DnaB_bind PF08278.6 OAP62825.1 - 0.16 12.1 0.0 6.9 6.9 0.0 2.3 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding Sugar_tr PF00083.19 OAP62827.1 - 1.8e-83 280.6 20.9 2e-83 280.4 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP62827.1 - 7.1e-24 84.1 17.9 7.1e-24 84.1 12.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP62827.1 - 2.1e-08 32.9 21.4 6.6e-07 28.0 1.2 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 OAP62827.1 - 2.1e-06 26.2 6.2 3.5e-05 22.2 0.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) SpoVAB PF13782.1 OAP62827.1 - 0.0049 16.8 0.3 2.4 8.1 0.1 3.1 3 0 0 3 3 3 2 Stage V sporulation protein AB S_locus_glycop PF00954.15 OAP62828.1 - 0.022 15.0 4.0 0.022 15.0 2.8 2.7 3 0 0 3 3 3 0 S-locus glycoprotein family DUF3504 PF12012.3 OAP62828.1 - 0.12 12.1 4.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) Plasmodium_Vir PF05795.6 OAP62828.1 - 0.33 10.1 5.2 0.48 9.5 3.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pol_alpha_B_N PF08418.5 OAP62828.1 - 3.5 7.1 13.0 4.8 6.6 9.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Mito_fiss_reg PF05308.6 OAP62828.1 - 5.2 6.3 9.1 8.6 5.6 6.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Med13_C PF06333.7 OAP62828.1 - 7.8 4.9 10.6 10 4.5 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DNA_pol_viral_N PF00242.12 OAP62828.1 - 8.4 5.3 7.8 11 4.8 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ribosomal_L10 PF00466.15 OAP62829.1 - 2.4e-17 62.7 0.0 3.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 AA_permease_2 PF13520.1 OAP62830.1 - 1.3e-60 205.2 61.1 1.3e-60 205.2 42.4 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP62830.1 - 1.1e-24 86.6 50.4 1.5e-24 86.1 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease PNP_UDP_1 PF01048.15 OAP62831.1 - 9.6e-16 57.4 0.0 2.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily Avirulence PF03377.8 OAP62831.1 - 0.014 14.0 0.6 0.023 13.4 0.4 1.2 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA MatE PF01554.13 OAP62832.1 - 1.5e-34 118.9 21.8 1.2e-32 112.7 5.5 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 OAP62832.1 - 0.00083 19.1 8.6 0.00083 19.1 5.9 3.2 1 1 2 3 3 3 1 Polysaccharide biosynthesis C-terminal domain PTPLA PF04387.9 OAP62833.1 - 8.1e-49 165.2 4.0 8.1e-49 165.2 2.8 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA GTP_EFTU PF00009.22 OAP62834.1 - 6.2e-54 182.2 0.0 9.8e-54 181.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 OAP62834.1 - 6.2e-15 54.8 0.0 1.7e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 OAP62834.1 - 6e-09 35.6 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 OAP62834.1 - 3.2e-07 30.3 0.0 1e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 OAP62834.1 - 0.00031 20.2 0.1 0.0033 16.9 0.0 2.7 3 0 0 3 3 3 1 Elongation factor G, domain IV SET PF00856.23 OAP62834.1 - 0.0093 16.2 0.2 0.079 13.2 0.0 2.4 3 0 0 3 3 3 1 SET domain MMR_HSR1 PF01926.18 OAP62834.1 - 0.0095 15.8 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FAD_binding_3 PF01494.14 OAP62836.1 - 2.9e-18 66.0 3.1 1.1e-12 47.7 0.3 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAP62836.1 - 1.5e-05 24.0 0.0 4.6e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP62836.1 - 0.00044 20.6 2.3 0.31 11.4 0.5 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP62836.1 - 0.00061 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 OAP62836.1 - 0.029 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 OAP62836.1 - 0.16 11.0 0.1 0.29 10.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Methyltransf_23 PF13489.1 OAP62837.1 - 1.8e-25 89.5 0.0 2.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP62837.1 - 1.3e-10 41.6 0.0 1.8e-09 37.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP62837.1 - 4.5e-09 36.8 0.0 4.9e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP62837.1 - 2.1e-08 33.8 0.0 3.2e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP62837.1 - 6.1e-08 33.0 0.0 5.4e-07 30.0 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP62837.1 - 6.7e-05 23.1 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP62837.1 - 0.0023 17.9 0.0 0.032 14.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP62837.1 - 0.0029 16.7 0.0 0.3 10.1 0.0 2.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 OAP62837.1 - 0.0071 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 OAP62837.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 OAP62837.1 - 0.061 12.4 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 OAP62837.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase EXOSC1 PF10447.4 OAP62838.1 - 8e-22 77.0 0.5 1.2e-21 76.4 0.3 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 OAP62838.1 - 3.8e-12 45.2 0.1 8.6e-12 44.1 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Arm PF00514.18 OAP62839.1 - 6.4e-71 232.0 29.6 1.5e-12 46.8 0.1 11.1 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAP62839.1 - 2.7e-24 85.2 12.4 5.6e-07 29.7 0.1 7.6 1 1 4 6 6 6 6 HEAT repeats HEAT PF02985.17 OAP62839.1 - 5.7e-19 66.4 15.1 0.043 13.9 0.0 9.2 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.1 OAP62839.1 - 1.5e-14 53.9 13.7 0.0022 18.3 0.0 8.2 6 2 3 9 9 9 6 HEAT-like repeat Arm_2 PF04826.8 OAP62839.1 - 4.6e-11 42.2 6.1 0.0025 16.9 0.1 3.6 2 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 OAP62839.1 - 8.6e-11 40.8 9.7 2.6e-06 26.0 0.1 2.8 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.7 OAP62839.1 - 2.6e-09 35.6 1.5 3.4e-09 35.2 0.1 1.8 2 1 1 3 3 3 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 OAP62839.1 - 6e-08 32.1 1.5 0.00072 18.7 1.0 3.7 2 1 1 3 3 3 2 V-ATPase subunit H HEAT_PBS PF03130.11 OAP62839.1 - 0.0022 18.3 10.1 3 8.5 0.6 6.8 7 0 0 7 7 6 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 OAP62839.1 - 0.028 14.3 6.3 28 4.6 0.0 4.9 2 1 3 6 6 6 0 V-ATPase subunit H eRF1_1 PF03463.10 OAP62839.1 - 0.054 13.0 1.3 0.087 12.3 0.2 1.8 2 0 0 2 2 2 0 eRF1 domain 1 Proteasom_PSMB PF10508.4 OAP62839.1 - 0.055 11.7 4.3 0.22 9.7 1.8 2.4 1 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.2 OAP62839.1 - 0.09 13.1 0.2 2.2 8.7 0.0 3.2 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Trypan_PARP PF05887.6 OAP62840.1 - 0.001 18.9 1.8 0.0024 17.7 1.3 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Mucin PF01456.12 OAP62840.1 - 0.081 12.6 14.3 0.068 12.9 9.1 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein NESP55 PF06390.7 OAP62840.1 - 0.11 11.8 7.4 0.18 11.1 5.1 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) U1snRNP70_N PF12220.3 OAP62841.1 - 6.2e-27 93.7 5.7 9.3e-27 93.1 4.0 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 OAP62841.1 - 1.7e-13 49.9 0.0 3.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP62841.1 - 2.8e-08 33.6 0.0 5.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP62841.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_4 PF01565.18 OAP62842.1 - 3.4e-21 75.1 3.6 8.2e-21 73.9 2.5 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAP62842.1 - 2.4e-12 46.5 0.0 5.9e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like L51_S25_CI-B8 PF05047.11 OAP62843.1 - 5.8e-08 32.3 0.1 8.8e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zf-C3HC4_2 PF13923.1 OAP62844.1 - 0.001 19.0 2.5 0.004 17.1 1.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP62844.1 - 0.0012 18.4 0.1 0.0021 17.6 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP62844.1 - 0.0027 17.5 0.3 0.005 16.6 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAP62844.1 - 0.0029 17.3 0.4 0.0054 16.4 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAP62844.1 - 0.28 11.0 1.4 0.73 9.7 0.1 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING VEFS-Box PF09733.4 OAP62844.1 - 2.6 7.7 4.0 4.5 6.9 0.3 2.2 2 0 0 2 2 2 0 VEFS-Box of polycomb protein Prp19 PF08606.6 OAP62845.1 - 7.8e-30 102.4 2.8 1.6e-29 101.4 1.9 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 OAP62845.1 - 3.3e-17 61.6 0.7 2e-05 24.2 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 OAP62845.1 - 3.4e-07 29.4 0.0 0.019 13.8 0.0 2.3 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 OAP62845.1 - 2e-05 24.4 0.0 0.00075 19.2 0.0 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A zf-Nse PF11789.3 OAP62845.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SnoaL_4 PF13577.1 OAP62845.1 - 0.026 14.4 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain DUF3312 PF11768.3 OAP62845.1 - 0.047 11.9 0.0 0.32 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Mito_fiss_reg PF05308.6 OAP62845.1 - 0.088 12.1 1.7 0.14 11.5 1.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Na_H_Exchanger PF00999.16 OAP62846.1 - 7e-35 120.2 31.5 3.2e-25 88.4 18.5 2.3 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family HTH_Tnp_1 PF01527.15 OAP62847.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Transposase MMR_HSR1 PF01926.18 OAP62848.1 - 1.3e-08 34.7 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 OAP62848.1 - 2.1e-05 23.7 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.1 OAP62848.1 - 0.0034 17.3 0.0 0.009 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.13 OAP62848.1 - 0.0045 16.2 0.0 0.009 15.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAP62848.1 - 0.006 16.4 1.1 5.8 6.7 0.0 3.3 3 1 1 4 4 4 1 Dynamin family DUF258 PF03193.11 OAP62848.1 - 0.0062 15.7 0.1 0.014 14.6 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 OAP62848.1 - 0.023 14.3 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase DUF3597 PF12200.3 OAP62848.1 - 0.075 13.4 0.1 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Miro PF08477.8 OAP62848.1 - 0.092 13.2 0.0 0.4 11.2 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_5 PF07728.9 OAP62848.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Fungal_trans_2 PF11951.3 OAP62849.1 - 9.1e-06 24.5 0.9 0.00082 18.0 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP62849.1 - 1.1e-05 25.2 11.2 2.2e-05 24.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1980 PF09323.5 OAP62850.1 - 0.42 10.3 3.6 0.16 11.7 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) DUF202 PF02656.10 OAP62850.1 - 5.7 7.2 11.8 5.7 7.2 0.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF202) AA_permease_2 PF13520.1 OAP62851.1 - 2.5e-50 171.2 45.6 3.5e-50 170.7 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP62851.1 - 1.6e-20 72.9 42.7 2.2e-20 72.4 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 OAP62852.1 - 1.2e-12 47.7 0.0 4.9e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP62852.1 - 1.3e-09 38.0 0.0 3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP62852.1 - 5.8e-09 35.8 0.3 1e-06 28.5 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP62852.1 - 3.2e-06 27.2 0.0 1.4e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAP62852.1 - 0.0026 17.5 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 OAP62852.1 - 0.0043 16.7 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein AA_permease_2 PF13520.1 OAP62854.1 - 4.2e-56 190.2 47.5 5.2e-56 189.9 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP62854.1 - 1.9e-29 102.3 38.7 2.5e-29 101.9 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease NACHT PF05729.7 OAP62855.1 - 8.8e-05 22.2 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 OAP62855.1 - 0.0036 16.3 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 OAP62855.1 - 0.0098 15.8 2.5 0.028 14.4 0.1 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 OAP62855.1 - 0.01 15.5 0.1 0.041 13.6 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 OAP62855.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SE PF00437.15 OAP62855.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 OAP62855.1 - 0.19 10.9 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 OAP62855.1 - 0.2 10.4 0.0 0.61 8.8 0.0 1.9 3 0 0 3 3 3 0 NB-ARC domain Homeobox PF00046.24 OAP62856.1 - 3.8e-18 64.8 4.8 7.9e-18 63.8 3.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 OAP62856.1 - 2.1e-05 24.1 1.8 6.2e-05 22.6 1.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Ndc1_Nup PF09531.5 OAP62856.1 - 1.4 7.2 4.8 2.1 6.6 3.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup E1-E2_ATPase PF00122.15 OAP62857.1 - 7.2e-24 84.0 0.0 2.1e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAP62857.1 - 4.7e-18 66.3 1.1 1.6e-13 51.6 0.8 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAP62857.1 - 1.8e-15 57.5 1.8 2.9e-14 53.6 0.6 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP62857.1 - 2.1e-09 37.2 0.0 5.9e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAP62857.1 - 0.00029 20.4 0.1 0.00079 19.0 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 OAP62858.1 - 1.4e-41 142.3 16.9 1.9e-41 141.9 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP62858.1 - 1.8e-10 39.9 7.5 1.8e-10 39.9 5.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 OAP62858.1 - 8.8e-07 27.4 5.1 1.2e-06 27.0 3.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 OAP62858.1 - 1.5e-05 23.7 5.7 0.0051 15.3 1.1 2.3 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_3 PF05977.8 OAP62858.1 - 0.01 14.0 6.2 0.013 13.6 4.3 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector WD40 PF00400.27 OAP62860.1 - 2.9e-05 23.7 5.8 0.6 10.0 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_2 PF13360.1 OAP62860.1 - 0.072 12.5 0.1 0.54 9.6 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain Apc4_WD40 PF12894.2 OAP62860.1 - 0.073 12.5 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.8 OAP62861.1 - 1.8e-10 40.8 0.0 3.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 OAP62861.1 - 1.2e-08 35.0 0.1 2.1e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 OAP62861.1 - 2.4e-06 27.0 0.0 4.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.7 OAP62861.1 - 6.8e-06 25.8 0.2 2e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 NACHT domain LCAT PF02450.10 OAP62861.1 - 7.8e-05 21.8 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 OAP62861.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 OAP62861.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 OAP62861.1 - 0.0027 17.9 0.0 0.0072 16.5 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain AAA_22 PF13401.1 OAP62861.1 - 0.0075 16.4 0.0 0.089 12.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 OAP62861.1 - 0.0075 15.9 0.0 0.028 14.1 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain DUF2075 PF09848.4 OAP62861.1 - 0.034 13.1 0.0 0.068 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 OAP62861.1 - 0.041 13.2 0.0 0.36 10.2 0.0 2.6 4 0 0 4 4 4 0 AAA domain Abhydrolase_1 PF00561.15 OAP62861.1 - 0.048 13.1 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 OAP62861.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 1 0 Cutinase Lipase_3 PF01764.20 OAP62861.1 - 0.083 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) ArgK PF03308.11 OAP62861.1 - 0.086 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 OAP62861.1 - 0.088 13.6 0.2 0.61 10.9 0.1 2.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAP62861.1 - 0.13 11.6 0.1 0.95 8.8 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 OAP62861.1 - 0.14 12.2 0.2 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Fructosamin_kin PF03881.9 OAP62862.1 - 1.8e-34 119.0 0.0 2.3e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 OAP62862.1 - 2.2e-13 50.5 0.1 3.2e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAP62862.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase PSD5 PF07637.6 OAP62862.1 - 0.14 12.2 0.5 18 5.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) adh_short_C2 PF13561.1 OAP62864.1 - 1.3e-28 100.4 0.1 1.5e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP62864.1 - 5e-24 85.0 0.2 6.5e-24 84.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62864.1 - 2.8e-08 33.6 0.1 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP62864.1 - 5.7e-05 22.6 0.0 0.00085 18.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP62864.1 - 0.012 15.3 1.2 0.033 13.9 0.8 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 OAP62864.1 - 0.025 14.9 0.2 0.2 12.1 0.2 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 OAP62864.1 - 0.082 11.9 0.1 0.26 10.3 0.0 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_M16_C PF05193.16 OAP62866.1 - 1.3e-46 158.5 0.0 4e-46 157.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 OAP62866.1 - 4e-40 136.9 0.0 6.7e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FHA PF00498.21 OAP62867.1 - 1.9e-12 47.0 0.0 3.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 OAP62867.1 - 1.2e-08 34.6 6.6 2.4e-08 33.6 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAP62867.1 - 0.0009 18.8 6.2 0.0019 17.8 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAP62867.1 - 0.00096 19.2 4.8 0.0025 17.8 3.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 OAP62867.1 - 0.001 18.6 3.9 0.0019 17.8 2.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_3 PF13920.1 OAP62867.1 - 0.0014 18.2 4.0 0.0026 17.4 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP62867.1 - 0.0021 17.7 5.3 0.0036 16.9 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAP62867.1 - 0.012 15.6 8.2 0.022 14.7 5.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAP62867.1 - 0.039 13.7 1.5 0.085 12.7 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 OAP62867.1 - 1.6 8.8 4.7 3.5 7.7 3.3 1.6 1 0 0 1 1 1 0 RING-like domain Alb1 PF09135.6 OAP62869.1 - 3.6e-16 59.7 8.3 3.6e-16 59.7 5.7 1.6 2 0 0 2 2 2 1 Alb1 Vps16_N PF04841.8 OAP62870.1 - 7.9e-100 334.2 0.0 1e-99 333.8 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 OAP62870.1 - 1.8e-80 270.2 0.0 2.5e-80 269.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region RCC1_2 PF13540.1 OAP62870.1 - 0.046 13.3 1.8 9.9 5.9 0.0 3.5 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat lci PF12197.3 OAP62870.1 - 0.048 13.2 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein GCR PF02155.10 OAP62870.1 - 0.15 10.7 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Glucocorticoid receptor DUF4652 PF15525.1 OAP62870.1 - 0.16 11.4 0.7 6.8 6.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4652) Abhydrolase_3 PF07859.8 OAP62872.1 - 1.7e-51 174.8 0.0 2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP62872.1 - 9.3e-09 35.1 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 OAP62872.1 - 6.1e-07 28.5 0.3 1.3e-06 27.4 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 OAP62872.1 - 4.9e-05 22.6 0.0 0.00033 19.9 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 OAP62872.1 - 0.00089 17.8 0.0 0.0012 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 OAP62872.1 - 0.0011 18.9 0.4 0.0019 18.0 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 OAP62872.1 - 0.0018 17.6 0.1 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2424 PF10340.4 OAP62872.1 - 0.0027 16.3 0.0 0.0035 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF1237 PF06824.6 OAP62874.1 - 6.6e-169 561.9 0.0 7.7e-169 561.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Trehalase PF01204.13 OAP62874.1 - 0.032 12.8 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 Trehalase CDC27 PF09507.5 OAP62875.1 - 1.6e-71 241.7 30.9 2.5e-70 237.8 21.4 2.0 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Fungal_trans PF04082.13 OAP62876.1 - 3.7e-12 45.6 0.5 1.3e-11 43.8 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain OPT PF03169.10 OAP62876.1 - 0.16 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF829 PF05705.9 OAP62877.1 - 1.3e-35 123.2 0.0 8.8e-34 117.2 0.0 2.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) TIP120 PF08623.5 OAP62878.1 - 5.7e-50 169.1 0.1 3.6e-48 163.3 0.0 3.2 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 OAP62878.1 - 2.5e-19 69.3 21.2 0.00057 20.1 0.0 9.0 8 3 1 9 9 9 6 HEAT repeats HEAT PF02985.17 OAP62878.1 - 6.5e-15 53.8 13.5 0.24 11.5 0.0 11.1 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 OAP62878.1 - 1.5e-09 38.0 29.8 0.5 10.9 0.0 13.4 12 4 4 16 16 16 2 HEAT-like repeat DUF2435 PF10363.4 OAP62878.1 - 5.6e-06 26.1 2.3 0.031 14.1 0.1 5.0 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 OAP62878.1 - 2.5e-05 24.5 3.1 0.051 13.9 0.0 5.7 7 1 1 8 8 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAP62878.1 - 0.023 14.0 0.2 7.3 5.8 0.0 4.3 3 1 1 4 4 4 0 CLASP N terminal GSH_synth_ATP PF03917.12 OAP62878.1 - 0.034 12.7 0.0 0.2 10.2 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic glutathione synthase, ATP binding domain MMS19_N PF14500.1 OAP62878.1 - 0.051 12.8 0.4 4.2 6.5 0.0 3.6 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF3385 PF11865.3 OAP62878.1 - 0.064 13.1 0.2 2.9 7.7 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) HEAT_PBS PF03130.11 OAP62878.1 - 0.78 10.3 7.9 15 6.3 0.0 5.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat SpoIIIAH PF12685.2 OAP62879.1 - 0.00076 19.0 2.3 0.00076 19.0 1.6 2.1 1 1 1 2 2 2 1 SpoIIIAH-like protein DUF1510 PF07423.6 OAP62879.1 - 0.069 12.5 22.5 0.043 13.1 14.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Mitofilin PF09731.4 OAP62879.1 - 0.36 9.4 18.4 0.44 9.1 12.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Presenilin PF01080.12 OAP62879.1 - 3.6 6.2 6.0 4.5 6.0 4.2 1.1 1 0 0 1 1 1 0 Presenilin TRAM_LAG1_CLN8 PF03798.11 OAP62880.1 - 5.3e-35 120.7 21.8 8.8e-35 120.0 15.1 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 OAP62880.1 - 2.2e-24 84.7 0.0 7.8e-24 82.9 0.0 2.0 1 0 0 1 1 1 1 TRAM1-like protein Ferric_reduct PF01794.14 OAP62881.1 - 3.7e-19 69.0 13.0 3.7e-19 69.0 9.0 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 OAP62881.1 - 1.3e-07 31.3 0.0 4.4e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 OAP62881.1 - 2.8e-06 27.3 1.4 0.0043 16.9 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 OAP62881.1 - 0.014 15.9 0.7 0.091 13.3 0.5 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain YTH PF04146.10 OAP62882.1 - 1.8e-29 102.1 0.0 2.8e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 OAP62882.1 - 0.0005 19.9 0.0 0.0016 18.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP62882.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) peroxidase PF00141.18 OAP62883.1 - 5.9e-26 91.3 0.0 1.4e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 Peroxidase FAD_binding_8 PF08022.7 OAP62884.1 - 8.6e-18 64.1 0.0 1.7e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 OAP62884.1 - 9.2e-16 58.0 14.8 9.2e-16 58.0 10.2 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAP62884.1 - 2.9e-07 30.5 0.0 5.1e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 OAP62884.1 - 0.0051 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fasciclin PF02469.17 OAP62885.1 - 7.9e-22 77.6 0.1 1.1e-09 38.3 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain DUF165 PF02592.10 OAP62885.1 - 0.074 13.2 1.2 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 MFS_1 PF07690.11 OAP62886.1 - 9.2e-16 57.4 56.5 4.7e-14 51.8 21.2 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 OAP62887.1 - 4.2e-34 117.6 0.0 5e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 OAP62888.1 - 2.3e-20 72.3 1.1 3.2e-20 71.9 0.8 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_3 PF13738.1 OAP62890.1 - 6.7e-18 65.4 0.0 1e-17 64.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP62890.1 - 3.7e-16 58.4 0.9 1.5e-15 56.4 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP62890.1 - 3.8e-10 39.6 0.0 8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP62890.1 - 2.6e-07 29.9 0.0 0.00018 20.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP62890.1 - 9.7e-07 28.6 0.0 8.9e-06 25.5 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP62890.1 - 0.039 13.8 0.0 1.2 8.9 0.0 2.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP62890.1 - 0.18 11.9 0.0 25 4.9 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.17 OAP62891.1 - 4.3e-59 200.2 0.0 5.9e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 OAP62892.1 - 4.4e-21 75.5 0.1 8.7e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.1 OAP62893.1 - 1.2e-08 34.6 11.0 0.00041 20.4 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP62893.1 - 1.5e-08 34.5 20.5 0.00061 19.9 0.2 5.0 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-BED PF02892.10 OAP62893.1 - 1.6e-05 24.5 10.3 0.014 15.1 0.1 3.9 2 2 1 3 3 3 2 BED zinc finger zf-C2H2_6 PF13912.1 OAP62893.1 - 0.00035 20.3 0.1 0.00035 20.3 0.1 2.9 4 0 0 4 4 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 OAP62893.1 - 0.00041 20.4 2.9 0.028 14.5 0.5 2.4 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-CHY PF05495.7 OAP62893.1 - 0.0022 18.1 3.9 0.077 13.1 2.7 2.3 1 1 0 1 1 1 1 CHY zinc finger GAGA PF09237.6 OAP62893.1 - 0.0041 16.6 3.6 0.0049 16.4 0.2 2.7 3 0 0 3 3 3 1 GAGA factor zf-Di19 PF05605.7 OAP62893.1 - 0.0048 16.9 9.8 0.034 14.2 0.2 3.1 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 OAP62893.1 - 0.017 15.3 13.5 0.11 12.7 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zinc_ribbon_5 PF13719.1 OAP62893.1 - 0.032 13.8 7.1 2.9 7.5 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain PyrI_C PF02748.10 OAP62893.1 - 0.035 13.5 3.5 1.1 8.7 0.0 3.2 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_4 PF13717.1 OAP62893.1 - 0.18 11.5 8.0 5 6.8 0.0 3.7 4 0 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.17 OAP62893.1 - 0.24 11.1 6.2 1.1 9.0 0.9 3.3 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHCC PF10276.4 OAP62893.1 - 0.25 11.2 3.9 20 5.1 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_7 PF15269.1 OAP62893.1 - 0.55 10.1 6.4 3.6 7.5 1.8 2.3 2 0 0 2 2 2 0 Zinc-finger PhnA_Zn_Ribbon PF08274.7 OAP62893.1 - 0.88 9.4 5.6 5.5 6.8 0.1 2.9 2 1 1 3 3 3 0 PhnA Zinc-Ribbon zf-RING_3 PF14369.1 OAP62893.1 - 1 9.3 7.6 58 3.8 4.0 3.3 2 1 1 3 3 3 0 zinc-finger zf-AN1 PF01428.11 OAP62893.1 - 3 7.8 8.1 4.7 7.1 1.1 3.6 3 1 1 4 4 4 0 AN1-like Zinc finger DZR PF12773.2 OAP62893.1 - 3.8 7.3 9.6 91 2.9 6.6 2.5 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 OAP62893.1 - 5.8 6.3 6.8 0.57 9.5 0.1 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding Cytochrome_C7 PF14522.1 OAP62893.1 - 5.9 6.5 9.7 2 8.0 1.5 2.2 1 1 1 2 2 2 0 Cytochrome c7 zf-C2H2_jaz PF12171.3 OAP62893.1 - 6.1 7.1 0.0 6.1 7.1 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 OAP62893.1 - 6.5 6.8 7.5 98 3.0 4.4 2.7 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 OAP62893.1 - 8.5 6.2 8.9 2 8.2 2.3 2.5 1 1 1 2 2 2 0 Transposase zinc-ribbon domain RRM_1 PF00076.17 OAP62894.1 - 6.8e-26 89.6 0.5 2.9e-12 46.0 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP62894.1 - 3.3e-16 58.8 0.0 2.8e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP62894.1 - 1.5e-15 56.9 0.1 2.5e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 OAP62894.1 - 0.015 14.7 0.0 0.14 11.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) ATP-synt_D PF01813.12 OAP62895.1 - 2e-65 220.0 1.7 2.5e-65 219.7 1.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF4578 PF15147.1 OAP62896.1 - 0.038 14.3 0.2 0.04 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Suf PF05843.9 OAP62897.1 - 8.2e-13 48.7 1.6 0.01 15.6 0.1 5.3 3 1 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_12 PF13424.1 OAP62897.1 - 4.5e-12 45.7 0.4 0.019 14.9 0.0 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP62897.1 - 1.1e-11 44.2 19.5 0.05 14.2 0.0 11.1 12 3 2 14 14 11 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP62897.1 - 3.5e-08 33.6 2.8 0.0056 16.9 0.2 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 OAP62897.1 - 9.8e-08 31.3 5.5 7.2e-05 21.9 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAP62897.1 - 7.3e-06 25.3 0.8 0.52 10.2 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP62897.1 - 1.1e-05 24.9 8.3 1.3 9.0 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAP62897.1 - 2.5e-05 23.8 4.7 1.6 8.4 0.0 6.2 8 0 0 8 8 6 1 TPR repeat TPR_16 PF13432.1 OAP62897.1 - 3.8e-05 24.2 17.3 0.00093 19.8 0.0 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP62897.1 - 0.00012 21.5 6.0 4 7.4 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat NRDE-2 PF08424.5 OAP62897.1 - 0.00019 20.4 3.6 0.64 8.8 0.0 4.5 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.7 OAP62897.1 - 0.0004 20.1 6.6 2.5 7.9 0.0 6.2 7 0 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_17 PF13431.1 OAP62897.1 - 0.00044 20.2 4.2 0.37 11.1 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat RPN7 PF10602.4 OAP62897.1 - 0.0031 16.9 0.2 0.033 13.5 0.1 2.7 3 1 0 3 3 3 1 26S proteasome subunit RPN7 PPR_3 PF13812.1 OAP62897.1 - 0.16 12.3 0.6 4.9 7.6 0.0 4.0 3 0 0 3 3 2 0 Pentatricopeptide repeat domain TPR_4 PF07721.9 OAP62897.1 - 0.31 11.5 14.6 1.2 9.8 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP62897.1 - 0.36 11.3 9.6 6.4 7.4 0.0 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat HAT PF02184.11 OAP62897.1 - 0.51 10.1 14.6 3.1 7.6 0.0 6.2 7 0 0 7 7 6 0 HAT (Half-A-TPR) repeat Aldedh PF00171.17 OAP62898.1 - 1.9e-122 408.9 0.0 2.2e-122 408.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP62898.1 - 0.0017 17.1 0.0 0.0065 15.2 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Chromate_transp PF02417.10 OAP62900.1 - 2e-51 173.9 29.5 2.4e-27 95.5 9.2 2.3 2 0 0 2 2 2 2 Chromate transporter Abhydrolase_6 PF12697.2 OAP62901.1 - 2.8e-33 115.7 1.3 3.5e-33 115.4 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP62901.1 - 2.1e-19 69.6 0.1 3.7e-19 68.9 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP62901.1 - 4.5e-08 32.9 0.1 2e-05 24.2 0.1 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAP62901.1 - 4e-05 23.3 0.1 0.00071 19.3 0.0 2.8 3 0 0 3 3 3 1 Putative lysophospholipase DUF2305 PF10230.4 OAP62901.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 OAP62901.1 - 0.017 14.7 0.2 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase DLH PF01738.13 OAP62901.1 - 0.037 13.2 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family GUN4 PF05419.7 OAP62901.1 - 0.09 12.5 0.3 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 GUN4-like TPR_12 PF13424.1 OAP62902.1 - 0.011 15.7 1.3 0.26 11.2 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP62902.1 - 0.033 14.8 2.9 33 5.4 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP62902.1 - 0.086 12.7 0.1 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.19 OAP62903.1 - 5.2e-143 477.1 15.0 6e-143 476.9 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PHO4 PF01384.15 OAP62904.1 - 3e-100 335.0 14.7 3.6e-100 334.7 10.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family ProRS-C_1 PF09180.6 OAP62905.1 - 9.3e-22 76.7 0.3 2.1e-21 75.5 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 OAP62905.1 - 7.2e-21 74.5 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAP62905.1 - 2.4e-12 46.6 0.0 6.5e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Acetyltransf_1 PF00583.19 OAP62906.1 - 1.4e-05 25.0 0.1 2.3e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP62906.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pho86 PF11124.3 OAP62906.1 - 0.043 12.8 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_10 PF13673.1 OAP62906.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Metallophos PF00149.23 OAP62907.1 - 4e-36 124.3 0.7 3.3e-29 101.7 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Methyltransf_33 PF10017.4 OAP62910.1 - 1.5e-30 105.6 3.7 1.9e-27 95.6 0.5 2.5 2 0 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 OAP62910.1 - 7.9e-19 68.0 1.9 7.5e-10 38.5 0.2 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 OAP62910.1 - 8.6e-06 26.1 0.6 3.9e-05 23.9 0.1 2.4 2 1 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 OAP62910.1 - 5.2e-05 23.5 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP62910.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.15 OAP62911.1 - 1.1e-10 41.7 0.2 2.4e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 OAP62911.1 - 2.9e-06 26.9 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) WD40 PF00400.27 OAP62912.1 - 1.6e-27 94.2 4.9 1.1e-07 31.4 0.2 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 OAP62912.1 - 0.00035 18.8 0.1 0.0068 14.5 0.0 2.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 S1 PF00575.18 OAP62913.1 - 2.2e-83 274.3 31.6 2.3e-15 56.4 1.9 12.4 12 0 0 12 12 12 11 S1 RNA binding domain TPR_14 PF13428.1 OAP62913.1 - 9.4e-08 32.0 0.1 0.12 13.1 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat Suf PF05843.9 OAP62913.1 - 1.5e-07 31.4 13.1 0.0031 17.2 0.1 4.5 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 OAP62913.1 - 2.4e-05 24.6 0.1 0.46 10.8 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAP62913.1 - 7.4e-05 22.6 0.1 0.01 15.7 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP62913.1 - 0.0042 17.7 0.0 0.54 11.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat S1_2 PF13509.1 OAP62913.1 - 0.0084 16.0 0.0 0.065 13.1 0.0 2.7 2 0 0 2 2 2 1 S1 domain TPR_11 PF13414.1 OAP62913.1 - 0.012 15.2 0.0 0.49 10.0 0.0 2.5 1 1 0 2 2 2 0 TPR repeat TPR_7 PF13176.1 OAP62913.1 - 0.037 13.8 0.0 0.037 13.8 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 OAP62913.1 - 0.062 12.3 0.2 0.51 9.3 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat YajC PF02699.10 OAP62913.1 - 9.9 5.9 11.6 19 5.0 0.7 4.9 5 0 0 5 5 5 0 Preprotein translocase subunit DNA_ligase_A_M PF01068.16 OAP62915.1 - 2.6e-48 164.0 0.0 6e-48 162.8 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAP62915.1 - 7.8e-38 130.0 0.0 1.7e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 OAP62915.1 - 2.9e-14 53.2 0.9 1.4e-12 47.7 0.0 3.2 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 OAP62915.1 - 1.8e-07 31.2 0.0 1.8e-07 31.2 0.0 2.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 OAP62915.1 - 0.016 14.9 0.1 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 DNA ligase IV EF-hand_4 PF12763.2 OAP62916.1 - 0.0017 18.0 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand GSK-3_bind PF05350.7 OAP62917.1 - 0.014 14.8 0.5 0.022 14.2 0.4 1.3 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding CPSase_L_D2 PF02786.12 OAP62918.1 - 4.6e-114 378.9 0.3 2e-83 278.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 OAP62918.1 - 1.3e-45 155.2 0.0 4.2e-45 153.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 OAP62918.1 - 6.2e-45 151.9 0.0 1.3e-44 150.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 OAP62918.1 - 1.1e-41 141.4 0.0 2.4e-41 140.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 OAP62918.1 - 2.7e-41 140.5 0.0 5.6e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 OAP62918.1 - 4.2e-39 133.0 0.0 6e-18 64.9 0.0 3.6 4 0 0 4 4 4 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 OAP62918.1 - 2.7e-35 121.7 0.2 2.3e-21 76.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 OAP62918.1 - 1.3e-34 119.4 0.0 3.1e-34 118.1 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 OAP62918.1 - 1.2e-21 76.3 0.0 5.6e-21 74.2 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 OAP62918.1 - 6.8e-21 74.3 0.0 3.6e-10 39.0 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 OAP62918.1 - 1.5e-16 60.4 0.4 3e-08 33.2 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 OAP62918.1 - 5.7e-16 58.3 0.1 1.7e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 OAP62918.1 - 4.2e-07 29.6 0.1 0.00011 21.7 0.1 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 OAP62918.1 - 1.2e-06 28.1 0.1 5.5e-05 22.7 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 OAP62918.1 - 7.1e-06 25.9 0.4 0.043 13.6 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 OAP62918.1 - 0.003 17.0 0.0 0.0077 15.6 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Ion_trans PF00520.26 OAP62919.1 - 2.3e-05 23.7 18.3 5.6e-05 22.4 12.7 1.6 1 0 0 1 1 1 1 Ion transport protein VID27 PF08553.5 OAP62919.1 - 4.3 5.4 10.3 8.2 4.5 7.1 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Synaptobrevin PF00957.16 OAP62920.1 - 3.9e-32 109.7 0.0 5.3e-32 109.2 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 OAP62920.1 - 3.6e-24 84.1 0.1 6.9e-24 83.2 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2628 PF10947.3 OAP62920.1 - 0.21 11.4 1.7 0.4 10.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) RRM_1 PF00076.17 OAP62922.1 - 3.7e-15 55.3 0.0 8.9e-15 54.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP62922.1 - 5.6e-13 48.6 0.0 8.9e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 OAP62922.1 - 6.6e-08 32.8 0.6 6.6e-08 32.8 0.4 2.7 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 OAP62922.1 - 2e-05 24.3 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Snf7 PF03357.16 OAP62923.1 - 1.2e-24 86.5 6.5 1.2e-24 86.5 4.5 1.9 1 1 1 2 2 2 1 Snf7 CS PF04969.11 OAP62924.1 - 6.4e-08 33.0 0.1 1e-07 32.3 0.1 1.3 1 0 0 1 1 1 1 CS domain Rep_1 PF01446.12 OAP62924.1 - 0.0078 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Replication protein LtrA PF06772.6 OAP62925.1 - 2.3e-20 72.8 17.5 3.2e-20 72.3 12.1 1.2 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF1129 PF06570.6 OAP62925.1 - 0.45 9.7 4.3 1.1 8.5 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF872 PF05915.7 OAP62925.1 - 4.5 7.1 6.9 0.52 10.1 0.6 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3021 PF11457.3 OAP62925.1 - 8.6 6.2 13.4 0.18 11.6 1.5 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3021) Sensor PF13796.1 OAP62926.1 - 0.59 9.7 4.0 0.17 11.4 0.2 1.9 2 0 0 2 2 2 0 Putative sensor zf-CCCH PF00642.19 OAP62927.1 - 1.1e-06 28.1 2.7 1.1e-06 28.1 1.9 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.27 OAP62929.1 - 0.027 14.3 0.1 0.74 9.7 0.1 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF3822 PF12864.2 OAP62929.1 - 0.57 9.3 0.0 1.3 8.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Phage_XkdX PF09693.5 OAP62929.1 - 0.66 9.5 0.0 1.3 8.6 0.0 1.5 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) MAS20 PF02064.10 OAP62930.1 - 2e-19 69.6 0.3 2.9e-18 65.9 0.2 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor PsbN PF02468.10 OAP62930.1 - 0.039 13.5 2.2 0.077 12.6 1.6 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Cu_amine_oxid PF01179.15 OAP62931.1 - 1.2e-162 541.3 0.0 1.6e-162 541.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 OAP62931.1 - 1.2e-07 31.7 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 OAP62931.1 - 0.00025 21.0 0.0 0.00078 19.4 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Aldedh PF00171.17 OAP62932.1 - 1.1e-181 604.1 0.5 1.3e-181 604.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hemerythrin PF01814.18 OAP62933.1 - 1.7e-10 41.1 2.8 2.4e-10 40.6 1.9 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ABC1 PF03109.11 OAP62933.1 - 0.11 12.5 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 ABC1 family DUF775 PF05603.7 OAP62934.1 - 4.3e-52 176.6 0.0 4.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ABC_membrane PF00664.18 OAP62935.1 - 1.2e-68 231.5 29.3 6.5e-41 140.5 5.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAP62935.1 - 1.4e-65 219.7 0.0 2e-32 112.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 OAP62935.1 - 3.4e-12 46.7 0.4 2.4e-05 24.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 OAP62935.1 - 6.5e-12 45.1 0.6 0.0037 16.5 0.1 4.4 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP62935.1 - 1.4e-11 44.9 0.0 0.015 15.2 0.0 4.2 4 0 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 OAP62935.1 - 1.5e-10 40.2 0.0 0.0014 17.2 0.1 3.8 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 OAP62935.1 - 2.1e-09 38.2 0.0 0.0002 22.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP62935.1 - 3.9e-08 32.6 0.0 0.005 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAP62935.1 - 9.8e-08 31.3 0.0 0.016 14.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Rad17 PF03215.10 OAP62935.1 - 1.4e-06 27.3 0.0 0.0024 16.6 0.0 2.7 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 OAP62935.1 - 1.6e-06 28.6 0.1 0.04 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAP62935.1 - 1.9e-06 28.0 1.6 0.099 12.7 0.1 3.6 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 OAP62935.1 - 6.4e-06 25.9 2.2 0.1 12.4 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 OAP62935.1 - 1.8e-05 24.4 0.0 0.056 13.1 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 OAP62935.1 - 5e-05 23.6 0.3 0.034 14.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 OAP62935.1 - 6.3e-05 22.8 0.0 0.31 10.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 OAP62935.1 - 0.00014 21.3 0.0 0.44 9.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 OAP62935.1 - 0.00051 19.7 0.1 0.3 10.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 OAP62935.1 - 0.00054 19.9 0.2 0.056 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 OAP62935.1 - 0.0013 18.3 0.0 0.84 9.1 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 OAP62935.1 - 0.0014 18.7 0.3 3.1 7.9 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 OAP62935.1 - 0.0016 18.6 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.20 OAP62935.1 - 0.0023 17.4 3.6 0.19 11.1 0.0 3.4 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 OAP62935.1 - 0.0048 16.3 0.2 5.3 6.4 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.2 OAP62935.1 - 0.0057 16.1 0.1 2.5 7.4 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain APS_kinase PF01583.15 OAP62935.1 - 0.0089 15.7 0.0 2.7 7.6 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_15 PF13175.1 OAP62935.1 - 0.009 15.1 0.0 3.1 6.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 OAP62935.1 - 0.013 14.5 0.1 6.7 5.7 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin G-alpha PF00503.15 OAP62935.1 - 0.016 13.9 0.0 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 OAP62935.1 - 0.016 15.0 0.0 5 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 OAP62935.1 - 0.048 13.6 0.0 6 6.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 OAP62935.1 - 0.048 13.4 0.0 2.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_24 PF13479.1 OAP62935.1 - 0.05 13.1 0.0 1.3 8.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 OAP62935.1 - 0.22 11.2 1.5 1.2 8.8 0.0 2.6 3 0 0 3 3 2 0 NTPase NUDIX PF00293.23 OAP62936.1 - 7.6e-08 32.0 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 OAP62937.1 - 9.3e-36 123.0 0.3 1.1e-35 122.8 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 OAP62938.1 - 2.6e-111 371.9 0.0 2.9e-111 371.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 OAP62940.1 - 1.3e-16 60.1 0.0 2.8e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain UPF0086 PF01868.11 OAP62941.1 - 6.5e-25 86.5 0.0 9.7e-25 86.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 MFS_1 PF07690.11 OAP62942.1 - 1.3e-07 30.6 21.0 1.3e-07 30.6 14.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAP62942.1 - 0.0035 16.8 5.0 0.0035 16.8 3.5 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF1129 PF06570.6 OAP62942.1 - 9.7 5.4 6.0 2.8 7.1 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Polysacc_deac_1 PF01522.16 OAP62943.1 - 8.6e-23 80.3 0.0 1.3e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 OAP62943.1 - 2.3e-06 27.1 0.0 5.4e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.10 OAP62943.1 - 0.0097 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Propeptide_C1 PF08127.8 OAP62943.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Peptidase family C1 propeptide Methyltransf_31 PF13847.1 OAP62944.1 - 5.8e-25 87.6 0.0 7.2e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP62944.1 - 1.1e-23 83.5 0.0 1.8e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP62944.1 - 1.6e-15 56.8 0.0 2.3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 OAP62944.1 - 4.1e-14 53.1 0.0 6.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP62944.1 - 1.5e-13 51.0 0.0 2.3e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP62944.1 - 2.8e-11 43.4 0.1 5.5e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP62944.1 - 1.1e-10 41.7 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP62944.1 - 4.9e-10 39.3 0.0 6.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP62944.1 - 6.8e-08 32.0 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 OAP62944.1 - 3.3e-05 23.3 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 OAP62944.1 - 0.0002 20.4 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 OAP62944.1 - 0.00021 20.9 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 OAP62944.1 - 0.00041 19.1 0.0 0.00057 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 OAP62944.1 - 0.00045 19.4 0.0 0.00059 19.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 OAP62944.1 - 0.00078 19.0 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 OAP62944.1 - 0.0026 16.8 0.0 0.0036 16.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 OAP62944.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF938 PF06080.7 OAP62944.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_8 PF05148.10 OAP62944.1 - 0.021 14.4 0.0 0.064 12.8 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.13 OAP62944.1 - 0.034 13.4 0.0 2.2 7.5 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_3 PF01596.12 OAP62944.1 - 0.045 12.7 0.0 0.063 12.3 0.0 1.3 1 1 0 1 1 1 0 O-methyltransferase Ceramidase PF05875.7 OAP62945.1 - 0.064 12.3 6.1 0.13 11.3 0.2 2.3 2 0 0 2 2 2 0 Ceramidase DUF3043 PF11241.3 OAP62945.1 - 2.7 7.5 5.1 0.68 9.4 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Fungal_trans_2 PF11951.3 OAP62946.1 - 2.5e-08 32.9 5.0 2.6e-06 26.2 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP62946.1 - 3.2e-07 30.1 11.0 6.7e-07 29.1 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RestrictionSfiI PF11487.3 OAP62946.1 - 0.0032 16.6 0.1 0.0061 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II restriction enzyme SfiI Integrin_b_cyt PF08725.6 OAP62946.1 - 0.034 13.5 0.8 0.099 12.0 0.6 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain MIT PF04212.13 OAP62946.1 - 0.057 13.3 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain WD40 PF00400.27 OAP62947.1 - 5.3e-18 64.1 10.4 0.00098 18.9 0.1 7.8 9 0 0 9 9 9 4 WD domain, G-beta repeat DUF829 PF05705.9 OAP62947.1 - 0.08 12.6 0.0 1.1 8.8 0.0 2.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Pantoate_ligase PF02569.10 OAP62948.1 - 4.5e-68 229.0 0.0 2.3e-67 226.7 0.0 1.9 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 OAP62949.1 - 1.4e-40 138.5 0.2 2e-40 138.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 OAP62949.1 - 3.8e-20 71.1 0.0 7.7e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 OAP62949.1 - 1e-18 66.9 0.0 2.1e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP62949.1 - 0.008 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.27 OAP62950.1 - 1.2e-18 66.1 11.1 0.00015 21.5 0.0 6.0 5 1 0 5 5 5 5 WD domain, G-beta repeat Rib_5-P_isom_A PF06026.9 OAP62951.1 - 7.3e-36 123.0 0.0 1.1e-32 112.6 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) ThiF PF00899.16 OAP62952.1 - 4.9e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 OAP62952.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 MoeZ/MoeB domain LRR_4 PF12799.2 OAP62953.1 - 3.1e-39 131.9 45.1 1.1e-07 31.2 1.1 11.1 7 2 6 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAP62953.1 - 6.7e-36 121.8 33.6 8.5e-08 31.8 0.8 9.3 5 2 3 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 OAP62953.1 - 9.7e-27 88.8 35.5 0.09 12.8 0.0 16.7 17 2 0 17 17 17 10 Leucine Rich Repeat LRR_7 PF13504.1 OAP62953.1 - 1.9e-21 72.3 32.5 1.2 9.5 0.0 16.3 16 1 1 17 17 17 7 Leucine rich repeat LRR_6 PF13516.1 OAP62953.1 - 2e-14 51.9 32.6 1.1 9.4 0.0 14.6 12 3 3 15 15 15 6 Leucine Rich repeat LRR_9 PF14580.1 OAP62953.1 - 0.15 11.6 9.1 1.1 8.7 0.9 3.7 2 1 1 4 4 4 0 Leucine-rich repeat TMEM192 PF14802.1 OAP62954.1 - 0.23 10.2 0.7 0.36 9.6 0.5 1.3 1 0 0 1 1 1 0 TMEM192 family DUF972 PF06156.8 OAP62954.1 - 0.9 9.9 8.3 0.17 12.2 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 OAP62954.1 - 1.9 8.3 12.4 1 9.1 6.0 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain Ribosomal_L13e PF01294.13 OAP62955.1 - 6.9e-61 204.8 3.8 6.9e-61 204.8 2.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L13e N_methyl_2 PF13544.1 OAP62955.1 - 0.53 9.8 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Type IV pilin N-term methylation site GFxxxE Pex19 PF04614.7 OAP62956.1 - 0.0047 16.5 3.7 0.0076 15.9 2.6 1.3 1 0 0 1 1 1 1 Pex19 protein family IncA PF04156.9 OAP62956.1 - 0.071 12.6 2.9 0.13 11.8 2.0 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 OAP62956.1 - 0.19 11.2 1.5 0.59 9.6 1.0 1.8 1 0 0 1 1 1 0 Septum formation initiator Sigma70_ner PF04546.8 OAP62956.1 - 0.78 9.3 12.0 0.047 13.3 4.6 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 OAP62956.1 - 3.2 5.6 10.7 0.82 7.6 5.2 1.6 2 0 0 2 2 2 0 CDC45-like protein DUF3433 PF11915.3 OAP62957.1 - 2.2e-28 98.2 9.5 3.6e-18 65.5 2.8 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Fungal_trans_2 PF11951.3 OAP62958.1 - 7e-08 31.4 0.0 6.7e-07 28.2 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP62960.1 - 1.7e-25 89.4 28.9 1.7e-25 89.4 20.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily GPI-anchored PF10342.4 OAP62961.1 - 1.1e-19 70.6 0.1 1.1e-19 70.6 0.1 2.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CLTH PF10607.4 OAP62963.1 - 2.6e-32 111.4 0.4 3.6e-32 111.0 0.3 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 OAP62963.1 - 2.3e-09 36.6 0.0 5.4e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 LisH MOZ_SAS PF01853.13 OAP62964.1 - 8.5e-79 263.1 0.3 4.1e-76 254.4 0.2 2.2 2 0 0 2 2 2 2 MOZ/SAS family Tudor-knot PF11717.3 OAP62964.1 - 3.8e-23 80.9 0.0 7.3e-23 80.0 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 OAP62964.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family WD40 PF00400.27 OAP62965.1 - 2.1e-26 90.8 5.6 2e-09 36.9 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 OAP62965.1 - 1.2e-06 27.0 1.2 0.00019 19.7 0.2 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cmc1 PF08583.5 OAP62966.1 - 6.1e-18 64.3 1.8 7.2e-18 64.1 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Flu_B_M2 PF04772.7 OAP62966.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) DUF726 PF05277.7 OAP62967.1 - 1.4e-127 425.3 2.0 2.1e-127 424.7 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glyco_tranf_2_3 PF13641.1 OAP62968.1 - 7.8e-20 71.6 0.3 7.8e-20 71.6 0.2 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAP62968.1 - 1.1e-07 31.3 0.1 6e-07 28.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 GRIP PF01465.15 OAP62969.1 - 5e-17 61.1 0.0 1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 GRIP domain YL1_C PF08265.6 OAP62969.1 - 5e-16 57.9 0.6 8.6e-16 57.1 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CENP-F_leu_zip PF10473.4 OAP62969.1 - 0.00012 21.9 20.3 0.00012 21.9 14.1 10.7 3 2 7 10 10 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 OAP62969.1 - 0.00045 18.1 72.3 0.00045 18.1 50.1 4.7 2 2 1 4 4 4 2 Myosin tail Fib_alpha PF08702.5 OAP62969.1 - 0.0013 18.9 3.4 0.0013 18.9 2.3 9.7 4 4 4 9 9 9 2 Fibrinogen alpha/beta chain family Uds1 PF15456.1 OAP62969.1 - 0.0033 17.3 10.5 0.0033 17.3 7.3 10.7 4 2 5 10 10 8 1 Up-regulated During Septation IncA PF04156.9 OAP62969.1 - 0.062 12.8 173.4 0.097 12.2 8.9 9.7 3 3 7 10 10 10 0 IncA protein Reo_sigmaC PF04582.7 OAP62969.1 - 0.062 12.4 66.2 0.14 11.2 1.6 7.6 3 2 5 8 8 8 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 OAP62969.1 - 0.091 12.0 162.8 0.073 12.3 15.7 9.8 4 2 5 9 9 9 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 OAP62969.1 - 0.13 10.6 122.7 2.6 6.4 20.8 6.5 2 1 2 5 5 5 0 AAA domain GAS PF13851.1 OAP62969.1 - 0.18 10.9 155.9 0.0071 15.5 8.0 9.8 3 3 4 8 8 8 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 OAP62969.1 - 3.6 6.5 149.9 0.11 11.5 13.1 7.7 3 2 3 7 7 7 0 Autophagy protein Apg6 Sulfotransfer_3 PF13469.1 OAP62970.1 - 1e-06 29.7 0.5 3.5e-06 28.0 0.3 1.8 1 1 0 1 1 1 1 Sulfotransferase family NmrA PF05368.8 OAP62971.1 - 5e-29 101.2 0.0 6.5e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP62971.1 - 4.1e-11 43.2 0.0 6.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP62971.1 - 3.6e-07 29.8 0.1 0.00078 18.9 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP62971.1 - 4.2e-07 28.9 0.4 6.8e-07 28.2 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 OAP62971.1 - 2.2e-05 24.7 0.0 0.0004 20.6 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 OAP62971.1 - 0.00089 18.3 0.2 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 OAP62971.1 - 0.008 16.0 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 OAP62971.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 OAP62971.1 - 0.015 15.2 0.0 0.034 14.0 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAP62971.1 - 0.057 12.3 0.1 0.082 11.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Actin PF00022.14 OAP62972.1 - 3.2e-49 167.4 0.0 3e-26 91.7 0.0 2.3 2 0 0 2 2 2 2 Actin bZIP_1 PF00170.16 OAP62974.1 - 1.2e-07 31.6 8.3 6.6e-07 29.1 5.8 1.9 1 1 0 1 1 1 1 bZIP transcription factor DUF501 PF04417.7 OAP62974.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF501) HALZ PF02183.13 OAP62974.1 - 0.038 13.7 0.3 0.065 12.9 0.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 OAP62974.1 - 0.15 11.8 9.5 14 5.6 6.6 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Peptidase_S10 PF00450.17 OAP62975.1 - 5.2e-76 256.4 0.1 8.8e-76 255.7 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_pol_A_bac PF01000.21 OAP62976.1 - 1.7e-28 98.9 0.0 2.7e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 OAP62976.1 - 1.9e-10 39.7 0.0 2.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Transketolase_N PF00456.16 OAP62977.1 - 3.7e-149 496.0 0.0 4.8e-149 495.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 OAP62977.1 - 2.7e-45 154.0 0.0 5.4e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAP62977.1 - 2.6e-11 43.5 0.0 4.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 OAP62977.1 - 2e-06 26.9 0.0 1.8e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 OAP62977.1 - 0.0019 16.9 0.1 0.0029 16.3 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Beta_elim_lyase PF01212.16 OAP62977.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase adh_short PF00106.20 OAP62978.1 - 4e-19 69.1 0.4 9.6e-19 67.9 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP62978.1 - 1.1e-07 31.6 0.2 1.5e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAP62978.1 - 5e-07 29.7 0.0 1.1e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAP62978.1 - 3.8e-06 27.0 0.2 2.3e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 OAP62978.1 - 2.6e-05 23.7 0.0 0.0037 16.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP62978.1 - 0.0068 15.1 0.0 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 OAP62978.1 - 0.016 14.4 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Spore_IV_A PF09547.5 OAP62978.1 - 0.056 12.1 0.0 0.072 11.7 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Semialdhyde_dh PF01118.19 OAP62978.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 OAP62978.1 - 0.13 12.0 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RRM_1 PF00076.17 OAP62979.1 - 3.8e-83 273.1 3.7 2e-21 75.3 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP62979.1 - 6.1e-57 189.5 0.6 1.1e-15 57.3 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP62979.1 - 5.2e-41 138.2 0.2 3e-09 36.5 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 OAP62979.1 - 7.9e-31 105.5 2.2 1.4e-30 104.7 0.2 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 OAP62979.1 - 8e-09 35.1 2.3 0.048 13.4 0.1 4.3 4 0 0 4 4 4 3 Limkain b1 Nup35_RRM_2 PF14605.1 OAP62979.1 - 2e-05 24.2 0.1 9 6.1 0.0 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 OAP62979.1 - 0.00092 19.4 0.0 3.2 8.0 0.0 3.1 2 0 0 2 2 2 2 Cobalamin biosynthesis central region OB_RNB PF08206.6 OAP62979.1 - 0.021 14.3 0.8 11 5.6 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.3 OAP62979.1 - 0.067 13.3 7.4 0.32 11.1 0.4 3.2 3 0 0 3 3 3 0 Heat induced stress protein YflT TC1 PF15063.1 OAP62979.1 - 0.073 12.6 0.1 5.1 6.7 0.0 3.1 3 0 0 3 3 3 0 Thyroid cancer protein 1 Mpv17_PMP22 PF04117.7 OAP62982.1 - 8e-15 54.2 1.7 4e-13 48.7 0.7 2.2 2 0 0 2 2 2 2 Mpv17 / PMP22 family DUF1275 PF06912.6 OAP62982.1 - 0.015 14.4 1.2 0.16 11.1 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1275) Serinc PF03348.10 OAP62982.1 - 0.056 12.1 1.5 0.081 11.6 1.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Cullin PF00888.17 OAP62983.1 - 1.5e-124 416.7 1.3 1.9e-124 416.3 0.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 OAP62983.1 - 1.6e-24 85.5 1.7 3.5e-24 84.3 1.2 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain TrmB PF01978.14 OAP62983.1 - 0.032 13.9 0.0 1.3 8.7 0.0 3.0 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Rep_fac-A_3 PF08661.6 OAP62984.1 - 3.6e-18 65.4 0.0 4.3e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1_2 PF15490.1 OAP62984.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit GATA PF00320.22 OAP62985.1 - 2.4e-05 23.5 8.7 0.0034 16.6 0.1 3.5 3 0 0 3 3 3 2 GATA zinc finger Dak1 PF02733.12 OAP62986.1 - 8.2e-111 369.6 1.9 1.4e-110 368.9 1.3 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 OAP62986.1 - 8.5e-48 162.3 1.7 2.2e-47 160.9 1.2 1.7 1 0 0 1 1 1 1 DAK2 domain RIO1 PF01163.17 OAP62987.1 - 4.2e-45 153.4 0.0 6.2e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 OAP62987.1 - 6.4e-29 99.8 0.0 1.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 OAP62987.1 - 1.5e-08 34.7 0.5 0.00059 19.6 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 OAP62987.1 - 2.6e-07 29.8 0.0 0.015 14.3 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA_bind_2 PF13725.1 OAP62987.1 - 0.095 12.8 0.1 0.46 10.6 0.0 2.1 3 0 0 3 3 3 0 Possible tRNA binding domain Kinesin PF00225.18 OAP62988.1 - 2.1e-92 309.4 1.1 3.9e-92 308.5 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Filament PF00038.16 OAP62988.1 - 0.00092 18.7 31.9 0.00092 18.7 22.1 8.3 3 2 3 6 6 6 2 Intermediate filament protein DUF787 PF05619.6 OAP62988.1 - 0.012 14.2 14.2 0.055 12.1 1.1 3.4 3 0 0 3 3 3 0 Borrelia burgdorferi protein of unknown function (DUF787) S-AdoMet_synt_C PF02773.11 OAP62989.1 - 1.1e-75 251.9 0.1 2.4e-75 250.8 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 OAP62989.1 - 3.6e-49 165.7 0.0 5.8e-49 165.0 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 OAP62989.1 - 1.3e-42 144.0 0.7 2e-42 143.5 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.12 OAP62990.1 - 3.6e-73 246.0 0.0 6.6e-73 245.1 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 OAP62990.1 - 4.6e-07 30.6 0.0 1.1e-06 29.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP62990.1 - 9.6e-05 22.0 0.1 0.00022 20.9 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 OAP62990.1 - 0.00039 20.3 0.0 0.00093 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAP62990.1 - 0.0016 18.6 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAP62990.1 - 0.002 18.1 0.0 0.0059 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 OAP62990.1 - 0.0021 18.3 0.0 0.0098 16.2 0.0 2.1 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 OAP62990.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 OAP62990.1 - 0.0025 17.3 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 OAP62990.1 - 0.0028 16.6 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.1 OAP62990.1 - 0.0034 17.0 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 OAP62990.1 - 0.0038 16.7 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 OAP62990.1 - 0.0064 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAP62990.1 - 0.0067 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein CbiA PF01656.18 OAP62990.1 - 0.007 15.7 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF463 PF04317.7 OAP62990.1 - 0.0091 14.6 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 1 YcjX-like family, DUF463 AAA PF00004.24 OAP62990.1 - 0.01 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 OAP62990.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ArsA_ATPase PF02374.10 OAP62990.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase NTPase_1 PF03266.10 OAP62990.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 NTPase UPF0079 PF02367.12 OAP62990.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 OAP62990.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 OAP62990.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 OAP62990.1 - 0.045 13.3 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 OAP62990.1 - 0.05 13.0 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 OAP62990.1 - 0.055 12.8 0.2 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 OAP62990.1 - 0.057 13.0 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.17 OAP62990.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 OAP62990.1 - 0.072 12.5 0.1 10 5.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain KaiC PF06745.8 OAP62990.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_31 PF13614.1 OAP62990.1 - 0.098 12.5 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 OAP62990.1 - 0.1 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Apq12 PF12716.2 OAP62991.1 - 8.4e-11 41.3 6.7 1.5e-10 40.5 4.7 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis CoatB PF10389.4 OAP62991.1 - 0.018 14.8 0.7 0.04 13.7 0.5 1.6 1 0 0 1 1 1 0 Bacteriophage coat protein B DUF2593 PF10767.4 OAP62991.1 - 0.06 13.0 1.9 0.082 12.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) V-ATPase_H_N PF03224.9 OAP62993.1 - 5.8e-79 265.4 0.0 7.8e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 OAP62993.1 - 8.2e-40 135.4 0.0 2.8e-39 133.7 0.0 2.0 1 0 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.17 OAP62993.1 - 0.019 14.9 0.1 0.15 12.2 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.1 OAP62993.1 - 0.027 14.7 0.2 0.32 11.3 0.0 2.8 2 2 0 2 2 2 0 HEAT repeats DUF619 PF04768.8 OAP62993.1 - 0.03 13.7 0.0 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF619) TMF_TATA_bd PF12325.3 OAP62994.1 - 1.4e-40 137.7 13.7 1.4e-40 137.7 9.5 7.0 2 1 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 OAP62994.1 - 1.8e-10 40.4 8.3 1.8e-10 40.4 5.8 9.8 7 2 2 10 10 10 3 TATA element modulatory factor 1 DNA binding IncA PF04156.9 OAP62994.1 - 0.0049 16.4 9.5 0.0049 16.4 6.6 5.9 2 1 4 6 6 6 2 IncA protein DUF3407 PF11887.3 OAP62994.1 - 9.7 5.3 11.6 0.12 11.6 1.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3407) Ank_2 PF12796.2 OAP62995.1 - 3e-46 155.6 4.9 1.6e-22 79.6 0.7 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 OAP62995.1 - 4.2e-37 124.1 8.7 2.5e-08 33.3 0.0 6.2 5 1 1 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 OAP62995.1 - 2.4e-36 123.4 14.9 6.8e-10 39.1 0.1 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP62995.1 - 1.8e-34 116.9 4.2 1.7e-10 40.8 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP62995.1 - 2.5e-31 104.5 1.4 4e-05 23.4 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Shal-type PF11601.3 OAP62995.1 - 0.016 14.7 1.5 0.2 11.1 0.0 2.3 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels Fungal_trans PF04082.13 OAP62996.1 - 6.2e-15 54.7 0.1 1.4e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FA_desaturase PF00487.19 OAP62996.1 - 0.14 11.5 0.6 0.27 10.6 0.4 1.4 1 0 0 1 1 1 0 Fatty acid desaturase K_trans PF02705.11 OAP62997.1 - 2.1e-178 594.0 16.7 2.1e-178 594.0 11.5 2.0 2 0 0 2 2 2 1 K+ potassium transporter GAGA_bind PF06217.7 OAP62997.1 - 0.00018 21.6 15.5 0.00028 20.9 10.8 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 OAP62997.1 - 0.023 13.9 25.8 0.044 12.9 17.9 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SET PF00856.23 OAP62997.1 - 0.11 12.7 0.9 0.23 11.7 0.6 1.5 1 0 0 1 1 1 0 SET domain DDHD PF02862.12 OAP62997.1 - 0.28 10.9 9.3 0.52 10.0 6.5 1.4 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 OAP62997.1 - 0.52 8.2 8.4 0.88 7.5 5.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3807 PF12720.2 OAP62997.1 - 0.64 10.1 20.2 1.6 8.8 14.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Neur_chan_memb PF02932.11 OAP62997.1 - 1 9.2 7.3 3.1 7.6 5.0 1.8 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region U79_P34 PF03064.11 OAP62997.1 - 1.6 8.1 19.2 2.9 7.3 13.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RR_TM4-6 PF06459.7 OAP62997.1 - 2 8.2 19.5 4.3 7.1 13.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rot1 PF10681.4 OAP62997.1 - 2.1 7.6 6.9 4.1 6.6 4.8 1.4 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Peptidase_U57 PF05582.7 OAP62997.1 - 2.6 6.9 14.2 5.4 5.8 9.8 1.4 1 0 0 1 1 1 0 YabG peptidase U57 LicD PF04991.8 OAP62997.1 - 3 7.8 15.1 5.7 6.9 10.5 1.3 1 0 0 1 1 1 0 LicD family Band_3_cyto PF07565.8 OAP62997.1 - 3.4 7.1 9.7 5.8 6.3 6.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NARP1 PF12569.3 OAP62997.1 - 4.9 5.7 31.5 7.8 5.1 21.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GCD14 PF08704.5 OAP62997.1 - 7.7 5.9 8.7 12 5.2 6.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit zf-RING_2 PF13639.1 OAP62998.1 - 3e-12 46.1 6.5 5.8e-12 45.2 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAP62998.1 - 5.2e-07 29.2 3.0 7.7e-07 28.7 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAP62998.1 - 5.8e-07 29.4 5.0 9.1e-07 28.8 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP62998.1 - 1.3e-06 27.9 2.5 2e-06 27.3 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAP62998.1 - 4.5e-06 26.6 3.4 4.5e-06 26.6 2.4 1.9 1 1 1 2 2 2 2 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAP62998.1 - 6.9e-06 25.6 3.3 1.2e-05 24.9 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MafB19-deam PF14437.1 OAP62998.1 - 0.00089 18.9 0.3 0.0014 18.2 0.0 1.4 2 0 0 2 2 2 1 MafB19-like deaminase zf-Apc11 PF12861.2 OAP62998.1 - 0.0053 16.5 2.2 0.012 15.3 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 OAP62998.1 - 0.015 15.0 5.2 0.12 12.1 3.6 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Baculo_IE-1 PF05290.6 OAP62998.1 - 0.081 12.6 0.7 0.14 11.9 0.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING-like PF08746.6 OAP62998.1 - 0.11 12.4 3.8 0.18 11.7 2.6 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 OAP62998.1 - 0.12 12.0 3.4 0.18 11.4 2.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 OAP62998.1 - 0.18 11.7 2.0 0.41 10.5 1.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2681 PF10883.3 OAP62998.1 - 0.22 11.7 1.4 0.32 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) RINGv PF12906.2 OAP62998.1 - 0.25 11.4 2.4 0.57 10.2 1.7 1.6 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.1 OAP62998.1 - 0.29 10.7 5.5 0.88 9.1 3.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 VPR PF00522.13 OAP63000.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 VPR/VPX protein Draxin PF15550.1 OAP63002.1 - 2.5 7.6 10.4 0.27 10.8 2.9 2.0 2 0 0 2 2 2 0 Draxin DUF1761 PF08570.5 OAP63003.1 - 0.26 11.2 2.3 2.6 8.0 1.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) IncA PF04156.9 OAP63003.1 - 6.7 6.2 5.9 17 4.9 4.1 1.7 1 1 0 1 1 1 0 IncA protein gag-asp_proteas PF13975.1 OAP63005.1 - 1.1e-05 25.1 0.0 3.3e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAP63005.1 - 0.0011 19.3 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 OAP63005.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.15 OAP63005.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease eIF3_subunit PF08597.5 OAP63006.1 - 3.3 7.1 14.3 4.5 6.7 9.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit WD40 PF00400.27 OAP63007.1 - 1.5e-55 183.1 13.0 1.6e-09 37.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAP63007.1 - 0.001 17.3 4.8 6.6 4.7 0.0 4.4 1 1 3 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 OAP63007.1 - 0.0094 15.4 0.2 4.2 6.7 0.0 2.6 2 1 0 2 2 2 2 PQQ-like domain DUF2269 PF10027.4 OAP63008.1 - 0.028 14.2 2.1 0.035 13.8 1.5 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) ADH_N PF08240.7 OAP63011.1 - 5.1e-28 96.9 0.5 9.8e-28 96.0 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 OAP63011.1 - 3.5e-10 39.3 0.3 8.4e-10 38.1 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 OAP63011.1 - 1.1e-09 37.9 0.8 2.5e-09 36.7 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 OAP63011.1 - 0.0048 15.4 0.4 0.012 14.0 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 OAP63011.1 - 0.022 13.6 0.8 0.03 13.1 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_18 PF12847.2 OAP63011.1 - 0.044 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 OAP63011.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP63011.1 - 0.06 13.7 0.3 0.21 12.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP63011.1 - 0.073 11.9 0.2 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 OAP63011.1 - 0.074 12.6 0.2 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 OAP63011.1 - 0.092 12.7 0.1 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 OAP63011.1 - 0.11 12.8 0.8 0.62 10.5 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Arm PF00514.18 OAP63012.1 - 2.2e-92 300.0 11.7 5.5e-14 51.3 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAP63012.1 - 2.1e-24 85.6 0.4 2e-10 40.8 0.0 5.5 1 1 5 6 6 6 4 HEAT repeats IBB PF01749.15 OAP63012.1 - 9.2e-21 73.8 4.2 1.6e-20 73.0 2.9 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 OAP63012.1 - 1.6e-20 72.9 8.3 6.4e-10 39.2 0.1 6.1 5 1 2 7 7 7 3 HEAT-like repeat HEAT PF02985.17 OAP63012.1 - 6.9e-20 69.2 0.1 1.2e-06 28.0 0.0 6.5 6 0 0 6 6 6 4 HEAT repeat Arm_2 PF04826.8 OAP63012.1 - 7.3e-12 44.9 0.0 0.00031 19.9 0.0 4.2 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 OAP63012.1 - 2.2e-06 26.2 0.0 0.00034 19.0 0.0 2.5 1 1 0 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 OAP63012.1 - 0.00019 21.3 0.0 1.5 8.7 0.0 4.5 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.11 OAP63012.1 - 0.00049 20.3 1.0 0.66 10.6 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 OAP63012.1 - 0.002 16.5 0.3 0.29 9.3 0.0 3.0 3 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 OAP63012.1 - 0.054 13.0 0.0 67 3.1 0.0 3.7 4 0 0 4 4 4 0 Glycosyl transferase family, helical bundle domain Mo25 PF08569.6 OAP63012.1 - 0.14 11.1 0.0 0.47 9.4 0.0 1.9 1 1 1 2 2 2 0 Mo25-like SURF6 PF04935.7 OAP63012.1 - 3.9 6.6 10.1 5.8 6.1 7.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 POT1 PF02765.12 OAP63013.1 - 1.5e-12 47.6 0.0 4.5e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Fungal_trans PF04082.13 OAP63014.1 - 7.4e-22 77.4 0.0 1.3e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAP63014.1 - 2.7e-08 33.6 12.7 0.00026 21.1 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP63014.1 - 2.6e-05 24.3 16.5 3e-05 24.0 4.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAP63014.1 - 0.0064 16.7 20.1 0.053 13.8 2.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger Nha1_C PF08619.5 OAP63015.1 - 4e-71 240.5 42.4 5.5e-71 240.1 29.4 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 OAP63015.1 - 8.1e-65 218.8 23.9 9.7e-65 218.5 16.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FlgD_ig PF13860.1 OAP63015.1 - 0.014 15.1 1.2 3.7 7.3 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain YrhC PF14143.1 OAP63015.1 - 0.042 13.7 2.8 0.12 12.3 0.1 2.8 3 0 0 3 3 3 0 YrhC-like protein DUF21 PF01595.15 OAP63015.1 - 0.24 10.6 9.5 0.28 10.4 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF21 Npa1 PF11707.3 OAP63016.1 - 2.5e-62 210.8 0.0 9.2e-62 208.9 0.0 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NA37 PF04245.8 OAP63016.1 - 0.019 14.2 0.3 0.065 12.5 0.0 1.8 2 0 0 2 2 2 0 37-kD nucleoid-associated bacterial protein Pyr_redox_2 PF07992.9 OAP63017.1 - 2.8e-20 73.0 0.0 4.3e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP63017.1 - 4.9e-12 46.0 0.0 3.1e-10 40.2 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 OAP63017.1 - 2.5e-06 26.3 0.1 1.1e-05 24.3 0.2 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 OAP63017.1 - 0.0002 21.3 0.0 0.00049 20.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 OAP63017.1 - 0.00034 20.2 0.2 0.0014 18.3 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 OAP63017.1 - 0.0014 17.9 0.2 0.0036 16.5 0.2 1.8 1 0 0 1 1 1 1 EF hand Nipped-B_C PF12830.2 OAP63018.1 - 3.2e-35 121.4 0.8 3.2e-35 121.4 0.6 3.3 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 OAP63018.1 - 3.8e-07 29.9 0.4 2.5e-06 27.3 0.2 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 OAP63018.1 - 8.4e-05 22.4 0.5 0.0062 16.4 0.1 3.6 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 OAP63018.1 - 0.2 11.7 9.9 0.73 10.0 0.1 5.8 7 0 0 7 7 7 0 HEAT repeat TFIIS_C PF01096.13 OAP63019.1 - 3.1e-13 49.0 2.8 3.1e-13 49.0 2.0 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 OAP63019.1 - 0.012 15.9 4.1 1.9 8.8 0.6 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.2 OAP63019.1 - 0.021 14.6 6.3 0.022 14.5 0.2 2.4 2 1 1 3 3 3 0 Double zinc ribbon Cytochrom_NNT PF03264.9 OAP63019.1 - 0.061 12.7 2.5 0.15 11.4 1.7 1.6 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region C1_1 PF00130.17 OAP63019.1 - 0.074 12.7 1.3 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cytochrome_C554 PF13435.1 OAP63019.1 - 0.2 11.7 2.6 0.66 10.0 1.0 1.7 1 1 0 1 1 1 0 Cytochrome c554 and c-prime zf-RING_4 PF14570.1 OAP63019.1 - 0.21 11.1 5.2 2.2 7.9 0.1 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Fer4_21 PF14697.1 OAP63019.1 - 0.54 10.1 7.1 1.5 8.7 1.7 2.4 2 1 0 2 2 1 0 4Fe-4S dicluster domain RNA_POL_M_15KD PF02150.11 OAP63019.1 - 0.87 9.3 5.1 0.85 9.3 1.0 2.6 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Cytochrom_c3_2 PF14537.1 OAP63019.1 - 1.2 9.5 5.5 4.5 7.6 3.8 2.0 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 OAP63019.1 - 2 8.1 7.8 65 3.2 5.4 2.3 1 1 0 1 1 1 0 Cytochrome c7 zf-UBR PF02207.15 OAP63019.1 - 2 8.1 6.5 1.8 8.3 0.1 2.5 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Nudix_N_2 PF14803.1 OAP63019.1 - 2.3 7.9 7.1 0.4 10.4 1.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal Zn-ribbon_8 PF09723.5 OAP63019.1 - 3.7 7.5 9.8 10 6.1 1.3 3.3 3 1 0 3 3 3 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 OAP63019.1 - 4.4 7.6 6.6 16 5.8 0.3 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain OrfB_Zn_ribbon PF07282.6 OAP63019.1 - 8.7 6.0 8.6 3.4 7.4 0.3 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain HEAT_2 PF13646.1 OAP63020.1 - 6.4e-31 106.4 4.8 1.5e-15 57.2 0.0 3.4 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.11 OAP63020.1 - 1e-19 68.9 2.8 0.041 14.3 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 OAP63020.1 - 7.6e-10 38.9 10.7 0.00025 21.4 0.1 4.6 2 2 2 4 4 4 3 HEAT-like repeat HEAT PF02985.17 OAP63020.1 - 1.1e-06 28.1 7.3 1.1 9.5 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.18 OAP63020.1 - 0.00061 19.5 0.1 0.59 10.0 0.0 3.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Choline_kin_N PF04428.9 OAP63020.1 - 0.033 13.6 0.0 4.3 6.8 0.0 3.4 3 1 0 3 3 3 0 Choline kinase N terminus DnaJ-X PF14308.1 OAP63020.1 - 0.11 11.8 0.3 1 8.5 0.1 2.0 2 0 0 2 2 2 0 X-domain of DnaJ-containing RuvA_C PF07499.8 OAP63020.1 - 0.13 12.4 1.4 5.1 7.3 0.0 3.4 4 0 0 4 4 4 0 RuvA, C-terminal domain DIM1 PF02966.11 OAP63021.1 - 1e-69 232.1 0.2 1.1e-69 232.0 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 OAP63021.1 - 0.00064 19.7 0.5 0.0014 18.6 0.3 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 OAP63021.1 - 0.0065 16.1 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin PIG-L PF02585.12 OAP63022.1 - 1.6e-22 80.3 0.0 3.8e-22 79.1 0.0 1.6 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase NQR2_RnfD_RnfE PF03116.10 OAP63022.1 - 0.014 14.6 0.0 0.37 9.9 0.0 2.2 2 0 0 2 2 2 0 NQR2, RnfD, RnfE family ATP13 PF12921.2 OAP63023.1 - 1.4e-24 85.7 0.0 2.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase expression LSM PF01423.17 OAP63024.1 - 7.8e-19 67.0 0.2 1.6e-18 66.0 0.2 1.5 1 1 0 1 1 1 1 LSM domain Flu_B_NS1 PF02942.9 OAP63024.1 - 0.082 11.7 0.1 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) GTP_EFTU PF00009.22 OAP63025.1 - 9.2e-22 77.3 0.0 1.9e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAP63025.1 - 1.2e-14 54.2 0.0 3.2e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAP63025.1 - 1.3e-09 37.9 1.2 1e-07 31.9 0.3 3.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 OAP63025.1 - 0.0039 16.6 0.1 0.55 9.7 0.0 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 OAP63025.1 - 0.015 15.8 0.0 0.096 13.1 0.0 2.4 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 OAP63025.1 - 0.018 15.0 0.1 0.058 13.3 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 OAP63025.1 - 0.039 13.5 1.2 0.063 12.9 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 OAP63025.1 - 0.1 12.4 0.1 0.36 10.6 0.1 1.9 1 0 0 1 1 1 0 Dynamin family CART PF06373.6 OAP63025.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) EamA PF00892.15 OAP63026.1 - 7e-06 26.0 15.2 1.9e-05 24.6 10.5 1.6 1 1 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 OAP63026.1 - 0.0025 17.5 5.3 0.0059 16.4 3.6 1.6 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 OAP63026.1 - 0.02 15.1 11.8 0.034 14.3 5.5 2.1 1 1 1 2 2 2 0 Multidrug resistance efflux transporter TPT PF03151.11 OAP63026.1 - 1.4 8.5 14.2 0.48 10.0 4.4 2.1 1 1 1 2 2 2 0 Triose-phosphate Transporter family DUF4452 PF14618.1 OAP63027.1 - 6e-59 198.5 13.6 7.5e-59 198.2 9.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Het-C PF07217.6 OAP63028.1 - 5.7e-267 886.8 0.0 1.3e-266 885.6 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C ECH PF00378.15 OAP63029.1 - 2e-41 141.7 0.0 7.1e-41 139.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 OAP63029.1 - 0.013 15.3 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 DUF221 PF02714.10 OAP63030.1 - 2.4e-103 345.4 26.1 3.9e-103 344.7 18.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAP63030.1 - 1.8e-41 141.3 7.2 1e-40 138.8 0.2 3.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 OAP63030.1 - 1.6e-14 53.5 0.0 4.7e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 OAP63030.1 - 3.9e-11 43.2 3.4 0.00011 22.6 1.6 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) OmpH PF03938.9 OAP63030.1 - 1.1 9.1 13.5 2.6 7.9 0.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF946 PF06101.6 OAP63031.1 - 1.9e-16 59.2 1.8 1.1e-15 56.7 0.2 2.3 2 1 0 2 2 2 1 Plant protein of unknown function (DUF946) NPP1 PF05630.6 OAP63031.1 - 0.16 11.7 0.0 0.37 10.4 0.0 1.6 2 0 0 2 2 2 0 Necrosis inducing protein (NPP1) Sec2p PF06428.6 OAP63032.1 - 1.2e-10 41.1 8.6 1.2e-10 41.1 6.0 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 OAP63032.1 - 1e-05 25.2 7.7 0.00088 18.9 1.2 2.2 2 0 0 2 2 2 2 IncA protein HSBP1 PF06825.7 OAP63032.1 - 0.0025 17.3 0.6 0.061 12.9 0.2 2.4 2 0 0 2 2 2 1 Heat shock factor binding protein 1 Med4 PF10018.4 OAP63032.1 - 0.0092 15.4 0.1 0.0092 15.4 0.1 2.8 2 1 1 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 Laminin_II PF06009.7 OAP63032.1 - 0.037 13.7 9.6 0.5 10.1 2.9 2.2 2 0 0 2 2 2 0 Laminin Domain II Jnk-SapK_ap_N PF09744.4 OAP63032.1 - 0.25 11.3 14.6 0.097 12.6 0.6 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Tektin PF03148.9 OAP63032.1 - 0.3 9.5 12.4 0.19 10.2 3.8 2.0 2 0 0 2 2 2 0 Tektin family DUF4140 PF13600.1 OAP63032.1 - 0.51 10.8 17.2 2.3 8.7 1.8 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Myosin_tail_1 PF01576.14 OAP63032.1 - 0.52 7.9 28.0 0.025 12.3 1.5 2.8 2 1 1 3 3 3 0 Myosin tail DUF2360 PF10152.4 OAP63032.1 - 0.83 9.9 10.6 3.5 7.8 7.3 2.2 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MscS_porin PF12795.2 OAP63032.1 - 1.5 8.0 23.6 1.6 7.9 4.2 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF972 PF06156.8 OAP63032.1 - 2.1 8.7 7.1 7.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF3403 PF11883.3 OAP63032.1 - 2.3 8.5 8.7 0.99 9.7 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) EMP24_GP25L PF01105.19 OAP63032.1 - 3 7.5 6.4 6.3 6.4 0.1 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Tropomyosin_1 PF12718.2 OAP63032.1 - 3.3 7.5 20.0 1.6 8.5 1.1 2.2 2 0 0 2 2 2 0 Tropomyosin like Kinesin-relat_1 PF12711.2 OAP63032.1 - 3.3 8.1 10.8 1.3 9.4 0.1 2.4 2 0 0 2 2 2 0 Kinesin motor CorA PF01544.13 OAP63032.1 - 3.3 6.6 5.5 1.7 7.6 0.2 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ATG16 PF08614.6 OAP63032.1 - 4.1 7.1 21.5 0.87 9.3 7.0 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) YlqD PF11068.3 OAP63032.1 - 4.9 7.2 13.1 0.6 10.1 3.0 2.3 2 0 0 2 2 2 0 YlqD protein V_ATPase_I PF01496.14 OAP63032.1 - 6.4 4.5 7.4 12 3.5 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family HAUS6_N PF14661.1 OAP63032.1 - 6.8 5.9 11.9 1.9 7.7 3.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus KilA-N PF04383.8 OAP63033.1 - 0.00064 19.3 0.4 0.0025 17.3 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain PseudoU_synth_2 PF00849.17 OAP63034.1 - 4.6e-26 91.6 0.0 9.2e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 OAP63034.1 - 6.9e-07 28.5 0.0 1.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain Auto_anti-p27 PF06677.7 OAP63034.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.9 OAP63034.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-DNL PF05180.7 OAP63034.1 - 0.16 11.7 0.0 0.49 10.1 0.0 1.8 1 0 0 1 1 1 0 DNL zinc finger Rad50_zn_hook PF04423.9 OAP63034.1 - 1.3 8.4 3.3 0.62 9.5 0.0 2.1 3 0 0 3 3 3 0 Rad50 zinc hook motif Ribosomal_L32e PF01655.13 OAP63035.1 - 2e-48 162.9 1.2 3.2e-48 162.3 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.17 OAP63036.1 - 2.4e-17 63.5 0.0 4.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP63036.1 - 2.2e-05 24.1 0.1 7.1e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Heme_oxygenase PF01126.15 OAP63037.1 - 3.2e-12 46.4 0.0 5.6e-12 45.6 0.0 1.3 1 1 0 1 1 1 1 Heme oxygenase DUF3134 PF11332.3 OAP63037.1 - 0.094 12.8 0.4 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) TT_ORF2a PF08197.6 OAP63038.1 - 0.0087 15.8 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 pORF2a truncated protein FYVE_2 PF02318.11 OAP63038.1 - 0.019 14.8 12.1 0.6 10.0 1.2 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Nucleo_P87 PF07267.6 OAP63038.1 - 1 7.9 5.0 1.4 7.5 3.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-C3HC4 PF00097.20 OAP63038.1 - 3.5 7.3 22.8 2.7 7.7 4.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.7 OAP63038.1 - 6.5 6.6 15.3 6.3 6.6 2.8 2.6 2 0 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS91 PF14319.1 OAP63038.1 - 8.5 5.9 19.9 2.1 7.8 4.5 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain Adaptin_N PF01602.15 OAP63039.1 - 2.2e-106 356.3 0.1 2.7e-106 355.9 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 OAP63039.1 - 1.3e-10 41.4 0.3 0.00019 21.6 0.0 4.8 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 OAP63039.1 - 1.4e-07 30.9 0.2 0.17 12.0 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 OAP63039.1 - 0.0018 18.7 2.5 23 5.6 0.0 5.4 5 0 0 5 5 5 0 HEAT-like repeat Cohesin_HEAT PF12765.2 OAP63039.1 - 0.0045 16.9 2.4 1.7 8.7 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Daxx PF03344.10 OAP63039.1 - 2.2 6.6 19.4 3.2 6.1 13.4 1.2 1 0 0 1 1 1 0 Daxx Family DNA_pol_phi PF04931.8 OAP63039.1 - 2.7 5.6 26.4 5 4.7 18.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Trypan_PARP PF05887.6 OAP63039.1 - 4.9 6.9 17.6 11 5.7 12.2 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.9 OAP63039.1 - 6.9 4.5 13.3 10 3.9 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 OAP63039.1 - 7.7 5.1 14.7 13 4.4 10.2 1.2 1 0 0 1 1 1 0 Paf1 Nuf2 PF03800.9 OAP63041.1 - 6.8e-41 139.6 0.3 6.8e-41 139.6 0.2 2.3 2 0 0 2 2 2 1 Nuf2 family SlyX PF04102.7 OAP63041.1 - 0.038 14.3 0.4 0.038 14.3 0.2 6.0 2 2 1 5 5 5 0 SlyX Reo_sigmaC PF04582.7 OAP63041.1 - 1.1 8.3 7.3 2 7.5 0.9 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein GAS PF13851.1 OAP63041.1 - 5.8 6.0 56.3 2.3 7.3 19.0 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SLA_LP_auto_ag PF05889.8 OAP63041.1 - 5.8 5.2 11.3 0.094 11.1 2.6 1.9 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) IF-2B PF01008.12 OAP63042.1 - 3e-32 111.7 0.0 5.3e-32 110.9 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family GATA PF00320.22 OAP63043.1 - 1.9e-30 103.8 19.4 3.8e-15 54.9 5.0 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 OAP63043.1 - 3.8e-06 26.1 4.1 0.0032 16.7 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 OAP63043.1 - 0.0026 17.5 1.6 1.1 9.1 0.2 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.7 OAP63043.1 - 0.0086 15.8 5.0 0.34 10.7 0.3 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.5 OAP63043.1 - 0.011 15.6 2.4 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 OAP63043.1 - 0.011 14.9 8.8 0.21 10.8 0.2 2.9 2 1 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 OAP63043.1 - 0.012 15.2 6.5 0.4 10.3 0.4 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.12 OAP63043.1 - 0.083 12.5 4.8 2.4 7.8 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-Sec23_Sec24 PF04810.10 OAP63043.1 - 0.11 12.0 0.2 0.11 12.0 0.2 2.7 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger HypA PF01155.14 OAP63043.1 - 0.69 9.6 2.8 3.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 OAP63043.1 - 2 8.3 16.3 0.59 10.0 0.6 3.3 2 2 1 3 3 3 0 Double zinc ribbon Nudix_N_2 PF14803.1 OAP63043.1 - 2.4 7.9 12.8 0.31 10.7 1.4 3.4 2 1 1 3 3 3 0 Nudix N-terminal ADK_lid PF05191.9 OAP63043.1 - 5 6.8 8.5 33 4.2 0.1 4.1 3 1 1 4 4 4 0 Adenylate kinase, active site lid Zn_Tnp_IS1595 PF12760.2 OAP63043.1 - 7.1 6.5 8.9 6.1 6.7 0.5 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain COPI_assoc PF08507.5 OAP63044.1 - 3e-44 150.0 4.3 3.3e-44 149.9 3.0 1.0 1 0 0 1 1 1 1 COPI associated protein ExoD PF06055.7 OAP63044.1 - 0.35 9.9 9.0 0.053 12.6 2.8 1.9 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD OTU PF02338.14 OAP63045.1 - 2.3e-15 57.2 0.0 6.2e-15 55.8 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease DAO PF01266.19 OAP63046.1 - 4.3e-26 91.6 0.5 5.2e-26 91.3 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP63046.1 - 0.0001 22.2 0.1 0.00037 20.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP63046.1 - 0.00045 19.1 0.5 0.00069 18.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 OAP63046.1 - 0.0029 16.7 0.1 0.0029 16.7 0.0 2.0 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 OAP63046.1 - 0.0029 17.4 0.2 0.0064 16.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP63046.1 - 0.054 12.5 0.1 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thioredoxin PF00085.15 OAP63048.1 - 8.2e-30 102.5 0.5 1.1e-29 102.1 0.3 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAP63048.1 - 5.8e-07 29.6 1.9 3.3e-06 27.2 0.5 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAP63048.1 - 2.4e-06 27.5 0.1 4.1e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 OAP63048.1 - 0.00027 20.4 0.2 0.00043 19.8 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.16 OAP63048.1 - 0.00037 20.1 0.1 0.00057 19.5 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 OAP63048.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 OAP63048.1 - 0.0014 18.1 0.7 0.065 12.7 0.2 2.0 1 1 1 2 2 2 1 Redoxin DIM1 PF02966.11 OAP63048.1 - 0.016 14.7 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_4 PF13462.1 OAP63048.1 - 0.091 12.7 0.2 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin Thioredox_DsbH PF03190.10 OAP63048.1 - 0.13 11.9 0.1 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Glutaredoxin PF00462.19 OAP63048.1 - 1.3 9.0 3.7 5.5 7.0 2.6 2.1 1 1 0 1 1 1 0 Glutaredoxin WD40 PF00400.27 OAP63049.1 - 4.7e-34 115.0 3.4 2.4e-08 33.5 0.0 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 OAP63049.1 - 0.0016 18.1 0.0 0.011 15.4 0.0 2.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.4 OAP63049.1 - 0.018 14.1 0.0 2.5 7.0 0.0 3.1 3 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Zn_Tnp_IS1595 PF12760.2 OAP63049.1 - 0.11 12.3 0.6 0.21 11.4 0.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 OAP63049.1 - 0.18 11.8 1.4 0.44 10.5 1.0 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 OAP63049.1 - 0.38 10.4 2.2 7.5 6.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 OAP63049.1 - 5.5 6.6 5.6 11 5.7 0.3 2.5 1 1 1 2 2 2 0 zinc-ribbon domain DCP2 PF05026.8 OAP63050.1 - 1.2e-36 124.5 0.8 2.3e-36 123.5 0.5 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 OAP63050.1 - 6.2e-18 64.7 0.1 1.3e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 OAP63051.1 - 7.2e-31 106.2 0.1 9.7e-31 105.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2392 PF10288.4 OAP63052.1 - 5e-19 68.6 0.0 8.1e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DZR PF12773.2 OAP63052.1 - 0.11 12.3 7.4 0.069 12.9 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 OAP63052.1 - 0.93 9.2 8.2 0.24 11.0 0.8 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Rad50_zn_hook PF04423.9 OAP63052.1 - 1.2 8.6 3.6 5.1 6.6 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif Lar_restr_allev PF14354.1 OAP63052.1 - 1.9 8.8 4.9 0.36 11.1 0.5 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar adh_short PF00106.20 OAP63054.1 - 1.1e-17 64.4 0.1 1e-16 61.3 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP63054.1 - 3.1e-14 53.3 0.0 2.5e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP63054.1 - 5.7e-09 35.8 0.1 9.4e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP63054.1 - 4.1e-06 25.9 0.0 5.3e-05 22.2 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 OAP63054.1 - 0.00029 20.3 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAP63054.1 - 0.00081 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 OAP63054.1 - 0.0049 15.8 0.1 0.0079 15.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 OAP63054.1 - 0.0082 16.5 0.1 0.022 15.1 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 OAP63054.1 - 0.023 13.3 0.1 0.039 12.6 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP63054.1 - 0.035 14.1 0.1 0.15 12.0 0.1 1.8 1 1 1 2 2 2 0 NADH(P)-binding HMG_CoA_synt_C PF08540.5 OAP63055.1 - 2.5e-102 342.1 0.6 3.2e-101 338.5 0.4 2.0 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 OAP63055.1 - 9.9e-94 311.7 0.2 1.6e-93 311.0 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal NTF2 PF02136.15 OAP63056.1 - 1.4e-33 115.7 0.4 2.4e-33 115.0 0.3 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Cg6151-P PF10233.4 OAP63057.1 - 4e-40 136.3 13.1 4.9e-40 136.0 9.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2207 PF09972.4 OAP63057.1 - 0.42 9.1 7.5 0.51 8.8 5.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-DHHC PF01529.15 OAP63057.1 - 4.8 6.5 5.9 6.2 6.1 4.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3040 PF11239.3 OAP63057.1 - 9.3 6.3 8.2 16 5.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF3433 PF11915.3 OAP63058.1 - 5.6e-32 109.7 14.9 1.9e-19 69.5 0.6 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) TPR_10 PF13374.1 OAP63059.1 - 8.9e-87 282.8 10.0 3.1e-13 49.1 0.1 8.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 OAP63059.1 - 1e-82 272.1 8.9 1.6e-16 59.9 0.2 6.8 3 1 6 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 OAP63059.1 - 1.1e-22 77.9 10.2 0.0065 16.1 0.0 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat HET PF06985.6 OAP63059.1 - 2.2e-21 76.5 10.4 8.5e-20 71.3 7.2 2.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_11 PF13414.1 OAP63059.1 - 1e-16 60.3 8.5 1.9e-08 33.8 0.1 6.5 7 0 0 7 7 7 3 TPR repeat TPR_1 PF00515.23 OAP63059.1 - 1.4e-13 49.7 19.3 0.0017 17.8 0.9 8.9 10 0 0 10 10 9 4 Tetratricopeptide repeat NB-ARC PF00931.17 OAP63059.1 - 2e-13 49.8 0.3 2e-12 46.5 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain TPR_2 PF07719.12 OAP63059.1 - 1.8e-12 46.1 18.7 0.2 11.6 1.0 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAP63059.1 - 2e-11 43.1 4.4 0.89 9.9 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAP63059.1 - 1.3e-10 40.6 4.1 1.8 9.2 0.0 7.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAP63059.1 - 7e-09 34.8 9.0 0.02 14.6 0.3 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP63059.1 - 1.5e-08 34.5 10.5 0.6 10.9 0.0 8.7 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP63059.1 - 1.4e-07 31.7 4.0 0.29 11.4 0.0 7.2 5 2 4 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 OAP63059.1 - 1.2e-06 28.5 0.1 0.74 9.9 0.0 5.7 2 1 4 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.1 OAP63059.1 - 2e-06 27.8 1.7 2.8e-05 24.1 1.2 2.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 OAP63059.1 - 3.2e-06 26.9 0.0 8e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_16 PF13432.1 OAP63059.1 - 7.6e-06 26.4 9.8 2.3 8.9 0.0 7.7 5 2 3 9 9 7 2 Tetratricopeptide repeat AAA_22 PF13401.1 OAP63059.1 - 2e-05 24.7 0.1 0.00041 20.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 OAP63059.1 - 0.014 15.1 0.1 0.034 13.8 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase DNAJ_related PF12339.3 OAP63059.1 - 0.023 14.5 2.2 7.8 6.3 0.0 3.7 3 1 1 4 4 4 0 DNA-J related protein CSTF2_hinge PF14327.1 OAP63059.1 - 0.22 11.6 0.5 0.55 10.3 0.3 1.6 1 1 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DIOX_N PF14226.1 OAP63060.1 - 1.7e-25 89.7 0.1 2.7e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP63060.1 - 6.6e-21 74.4 0.0 1.6e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glucosamine_iso PF01182.15 OAP63060.1 - 0.046 13.4 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Amidohydro_2 PF04909.9 OAP63061.1 - 3.3e-37 128.5 0.5 6.2e-37 127.6 0.3 1.5 1 1 0 1 1 1 1 Amidohydrolase Mei4 PF13971.1 OAP63062.1 - 0.031 13.2 0.0 0.068 12.1 0.0 1.5 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 TAFH PF07531.9 OAP63062.1 - 0.13 11.9 0.2 9.4 5.9 0.0 3.5 3 1 0 4 4 4 0 NHR1 homology to TAF DnaJ PF00226.26 OAP63063.1 - 1.8e-18 66.0 0.2 4.8e-18 64.6 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain ZYG-11_interact PF05884.7 OAP63063.1 - 0.044 12.8 0.4 0.062 12.3 0.3 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Med9 PF07544.8 OAP63063.1 - 0.054 13.2 2.5 0.12 12.0 1.7 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 GCV_T PF01571.16 OAP63064.1 - 9.2e-16 57.8 0.0 4.4e-13 49.0 0.0 2.1 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 OAP63064.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.7 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain zf-H2C2_2 PF13465.1 OAP63064.1 - 8.1 6.9 6.5 32 5.0 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain ABM PF03992.11 OAP63065.1 - 0.00091 19.2 0.2 0.0014 18.6 0.2 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Vir_act_alpha_C PF10400.4 OAP63065.1 - 0.038 14.3 0.2 0.2 12.0 0.0 1.9 1 1 1 2 2 2 0 Virulence activator alpha C-term QLQ PF08880.6 OAP63065.1 - 0.11 11.9 1.4 0.18 11.2 1.0 1.4 1 0 0 1 1 1 0 QLQ ABC2_membrane PF01061.19 OAP63066.1 - 9.8e-89 296.0 59.0 1.6e-46 158.0 12.6 3.3 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 OAP63066.1 - 1.1e-35 121.3 0.0 7.6e-31 105.8 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 OAP63066.1 - 1.8e-35 122.2 0.0 2.2e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 OAP63066.1 - 2.6e-17 62.6 0.0 6.7e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 OAP63066.1 - 4.1e-10 39.2 44.6 2.1e-07 30.3 13.5 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 OAP63066.1 - 5.9e-09 35.6 0.0 0.00039 19.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAP63066.1 - 6.1e-06 26.3 0.5 0.01 15.8 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 OAP63066.1 - 2.2e-05 23.7 0.0 0.001 18.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 OAP63066.1 - 4.4e-05 23.8 0.0 0.033 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAP63066.1 - 6.4e-05 22.8 0.0 0.042 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAP63066.1 - 0.0001 23.1 0.0 0.056 14.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAP63066.1 - 0.00028 20.3 2.1 0.038 13.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 OAP63066.1 - 0.00044 20.4 0.1 0.28 11.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 OAP63066.1 - 0.00049 19.5 1.7 0.0077 15.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 OAP63066.1 - 0.0099 15.8 0.0 0.98 9.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 OAP63066.1 - 0.021 14.4 1.5 3.7 7.1 0.2 2.7 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 OAP63066.1 - 0.032 13.4 0.0 1 8.5 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 OAP63066.1 - 0.036 13.8 1.5 8.8 6.1 0.3 2.6 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 OAP63066.1 - 0.037 13.5 0.1 1 8.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 OAP63066.1 - 0.086 13.0 0.2 11 6.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 OAP63066.1 - 0.094 12.6 0.1 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 OAP63066.1 - 0.1 12.0 0.1 11 5.3 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_30 PF13604.1 OAP63066.1 - 0.16 11.4 0.1 4.7 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 OAP63066.1 - 0.25 10.9 3.0 0.88 9.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRP9-21 PF05486.7 OAP63067.1 - 2.1e-23 81.8 0.7 4.5e-23 80.7 0.5 1.5 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 OAP63068.1 - 2.9e-119 397.2 0.9 3.6e-119 396.9 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.5 OAP63068.1 - 0.12 11.1 0.2 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 XcyI restriction endonuclease Mito_carr PF00153.22 OAP63069.1 - 3.6e-59 196.4 3.1 1.9e-20 72.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 OAP63070.1 - 4.5e-16 58.0 1.4 1.5e-08 34.1 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat MRG PF05712.8 OAP63070.1 - 0.0069 15.3 0.2 0.015 14.2 0.1 1.5 1 1 0 1 1 1 1 MRG DUF4613 PF15390.1 OAP63070.1 - 0.062 11.4 0.0 0.14 10.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) DUF3312 PF11768.3 OAP63070.1 - 0.2 9.8 0.0 0.32 9.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1308 PF07000.6 OAP63071.1 - 1e-60 205.3 0.1 1.5e-60 204.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Lung_7-TM_R PF06814.8 OAP63072.1 - 6e-71 238.7 17.7 7.2e-71 238.5 12.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor OHCU_decarbox PF09349.5 OAP63073.1 - 1.8e-27 96.5 0.1 2.2e-27 96.2 0.1 1.1 1 0 0 1 1 1 1 OHCU decarboxylase HHH_5 PF14520.1 OAP63073.1 - 0.017 15.3 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain Thioredoxin PF00085.15 OAP63075.1 - 3.9e-63 209.6 0.0 1.6e-30 104.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 OAP63075.1 - 5.3e-21 75.0 0.5 2.3e-20 73.0 0.1 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 OAP63075.1 - 3.6e-20 72.2 0.0 4.4e-09 36.5 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAP63075.1 - 2.3e-13 50.0 0.0 3.9e-05 23.6 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 OAP63075.1 - 3e-12 46.3 0.0 2.2e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 OAP63075.1 - 4.5e-09 36.0 0.1 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 OAP63075.1 - 5.7e-08 32.4 0.3 0.001 18.6 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 OAP63075.1 - 6.5e-06 26.0 0.0 0.06 13.1 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.1 OAP63075.1 - 3.8e-05 23.7 0.2 0.39 10.7 0.0 3.5 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_9 PF14595.1 OAP63075.1 - 0.00016 21.2 0.0 0.17 11.4 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 OAP63075.1 - 0.00084 19.1 0.0 0.21 11.4 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin domain Glutaredoxin PF00462.19 OAP63075.1 - 0.023 14.6 0.1 8.8 6.4 0.0 3.2 2 1 0 2 2 2 0 Glutaredoxin DDE_Tnp_1_2 PF13586.1 OAP63075.1 - 0.05 13.8 0.0 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain HSBP1 PF06825.7 OAP63076.1 - 1.4e-11 43.7 0.8 2e-11 43.2 0.6 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 PhoU_div PF01865.11 OAP63076.1 - 0.016 14.3 0.0 0.018 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF47 DUF935 PF06074.7 OAP63076.1 - 0.022 13.4 0.1 0.024 13.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Lipoprotein_7 PF01540.11 OAP63076.1 - 0.089 11.8 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Adhesin lipoprotein FAD_binding_3 PF01494.14 OAP63079.1 - 2e-96 323.1 0.0 2.6e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP63079.1 - 5.8e-11 41.8 0.0 8.8e-05 21.5 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP63079.1 - 3.4e-08 33.6 0.2 3.9e-07 30.1 0.2 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP63079.1 - 1.5e-07 31.7 0.9 0.0016 18.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP63079.1 - 6.5e-06 25.2 0.7 0.01 14.7 0.2 2.2 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 OAP63079.1 - 1.3e-05 25.3 0.1 6.3e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP63079.1 - 0.00037 20.4 0.2 0.00095 19.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 OAP63079.1 - 0.017 14.2 0.2 0.098 11.7 0.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 OAP63079.1 - 0.026 13.1 0.8 1.8 7.0 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 OAP63079.1 - 0.032 13.3 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 OAP63079.1 - 0.041 12.3 0.5 4.4 5.6 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Ebp2 PF05890.7 OAP63080.1 - 2.7e-84 282.6 13.4 2.7e-84 282.6 9.3 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Nop14 PF04147.7 OAP63081.1 - 0.0017 16.4 11.6 0.0021 16.0 8.0 1.2 1 0 0 1 1 1 1 Nop14-like family CobT PF06213.7 OAP63081.1 - 0.0021 17.2 13.4 0.0035 16.5 9.3 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DNMT1-RFD PF12047.3 OAP63081.1 - 0.0037 16.9 1.1 0.0065 16.1 0.0 1.9 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Mpp10 PF04006.7 OAP63081.1 - 0.0038 15.6 11.0 0.0054 15.1 7.6 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF2722 PF10846.3 OAP63081.1 - 0.058 12.4 4.7 0.091 11.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.9 OAP63081.1 - 0.083 10.9 10.4 0.12 10.4 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.4 OAP63081.1 - 0.13 9.8 2.0 0.14 9.6 1.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit VID27 PF08553.5 OAP63081.1 - 0.26 9.4 11.0 0.35 9.0 7.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 OAP63081.1 - 0.4 9.1 15.5 0.63 8.4 10.8 1.2 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 OAP63081.1 - 0.73 9.8 6.6 1.3 9.0 4.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 OAP63081.1 - 1.8 7.8 14.0 2.9 7.1 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AIF-MLS PF14962.1 OAP63081.1 - 2.5 7.7 6.0 4.7 6.8 4.2 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence TFIIA PF03153.8 OAP63081.1 - 3.2 7.5 14.9 5.7 6.7 10.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.5 OAP63081.1 - 4.1 6.3 15.8 6.7 5.6 11.0 1.3 1 0 0 1 1 1 0 BUD22 TLP-20 PF06088.6 OAP63081.1 - 7.5 6.1 7.6 2.8 7.5 3.2 1.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NOA36 PF06524.7 OAP63081.1 - 8.5 5.5 11.0 14 4.8 7.6 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2201_N PF13203.1 OAP63081.1 - 8.7 5.4 11.7 1.9 7.5 3.6 2.4 2 1 0 2 2 2 0 Putative metallopeptidase domain TruB_N PF01509.13 OAP63082.1 - 7.8e-43 146.1 0.0 6.4e-42 143.2 0.0 2.1 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DOT1 PF08123.8 OAP63083.1 - 5.6e-73 244.6 0.0 9.8e-73 243.8 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 OAP63083.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ORC6 PF05460.8 OAP63083.1 - 1.6 7.7 11.9 2.5 7.1 8.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ATG16 PF08614.6 OAP63084.1 - 5.5e-40 137.2 10.3 6.3e-40 137.0 7.1 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Metal_resist PF13801.1 OAP63084.1 - 0.0037 17.2 2.5 0.0037 17.2 1.7 2.0 3 0 0 3 3 2 1 Heavy-metal resistance Atg14 PF10186.4 OAP63084.1 - 0.0042 16.0 9.7 0.007 15.3 6.7 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CCDC144C PF14915.1 OAP63084.1 - 0.0044 15.9 11.4 0.0044 15.9 7.9 1.7 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region DUF2353 PF09789.4 OAP63084.1 - 0.0093 15.2 9.7 0.014 14.6 6.8 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Reo_sigmaC PF04582.7 OAP63084.1 - 0.015 14.5 1.6 0.019 14.1 1.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Leu_zip PF15294.1 OAP63084.1 - 0.018 14.1 13.2 0.011 14.8 7.9 1.5 2 0 0 2 2 2 0 Leucine zipper KIAA1430 PF13879.1 OAP63084.1 - 0.025 14.9 4.6 0.051 14.0 2.7 1.9 1 1 0 1 1 1 0 KIAA1430 homologue DUF4201 PF13870.1 OAP63084.1 - 0.036 13.4 12.1 0.069 12.5 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Pox_A_type_inc PF04508.7 OAP63084.1 - 0.07 12.9 0.3 0.96 9.3 0.2 2.9 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DUF3584 PF12128.3 OAP63084.1 - 0.078 10.2 11.2 0.096 9.9 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GvpG PF05120.7 OAP63084.1 - 0.098 12.4 8.2 0.12 12.1 2.3 2.5 1 1 0 2 2 2 0 Gas vesicle protein G DUF4140 PF13600.1 OAP63084.1 - 0.15 12.5 0.4 0.15 12.5 0.3 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.7 OAP63084.1 - 0.2 11.3 21.0 2.9 7.6 10.7 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.4 OAP63084.1 - 0.37 9.2 11.4 0.29 9.5 6.0 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 Lebercilin PF15619.1 OAP63084.1 - 0.49 9.7 17.9 0.098 12.0 9.8 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF972 PF06156.8 OAP63084.1 - 0.63 10.4 11.8 4.4 7.6 3.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) CENP-H PF05837.7 OAP63084.1 - 0.77 9.9 12.9 0.84 9.8 2.1 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.3 OAP63084.1 - 0.96 9.3 18.7 0.24 11.2 1.7 3.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.7 OAP63084.1 - 1.1 7.5 5.4 1.8 6.8 3.7 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2570 PF10828.3 OAP63084.1 - 1.4 8.5 7.6 2.9 7.5 3.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) IncA PF04156.9 OAP63084.1 - 1.5 8.4 17.9 28 4.2 9.9 2.6 1 1 0 2 2 2 0 IncA protein Filament PF00038.16 OAP63084.1 - 1.6 8.1 16.3 1.4 8.3 7.9 2.3 2 1 1 3 3 3 0 Intermediate filament protein DUF4407 PF14362.1 OAP63084.1 - 2 7.2 12.6 3.5 6.5 8.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Nup54 PF13874.1 OAP63084.1 - 2.5 7.7 13.2 2.3 7.8 0.7 2.6 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF4164 PF13747.1 OAP63084.1 - 3.1 7.9 22.5 0.55 10.3 5.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) WXG100 PF06013.7 OAP63084.1 - 4.4 7.3 8.8 51 3.9 2.6 3.1 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Laminin_II PF06009.7 OAP63084.1 - 4.8 6.9 10.9 8 6.2 4.6 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF2968 PF11180.3 OAP63084.1 - 5.8 6.2 15.9 0.47 9.7 6.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Spc7 PF08317.6 OAP63084.1 - 7.4 5.1 13.5 10 4.6 8.5 1.8 2 1 0 2 2 2 0 Spc7 kinetochore protein Ras PF00071.17 OAP63085.1 - 2.8e-57 192.6 0.1 3.3e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP63085.1 - 3.8e-20 72.5 0.0 5.4e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP63085.1 - 1.8e-13 50.1 0.0 2.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAP63085.1 - 1.2e-07 31.1 0.0 1.4e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAP63085.1 - 1.6e-07 31.2 0.0 2.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAP63085.1 - 3.7e-07 29.7 0.0 7.5e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 OAP63085.1 - 0.00065 19.1 0.0 0.0077 15.6 0.0 2.0 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 OAP63085.1 - 0.00077 18.6 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAP63085.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 OAP63085.1 - 0.0014 18.1 0.0 0.077 12.4 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 OAP63085.1 - 0.0028 16.8 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 OAP63085.1 - 0.0033 16.9 0.1 0.13 11.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 OAP63085.1 - 0.0036 17.3 0.0 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 OAP63085.1 - 0.004 16.7 0.1 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAP63085.1 - 0.0059 16.3 0.1 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Septin PF00735.13 OAP63085.1 - 0.0084 15.1 0.1 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_10 PF12846.2 OAP63085.1 - 0.0087 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain NTPase_1 PF03266.10 OAP63085.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase MobB PF03205.9 OAP63085.1 - 0.024 14.3 0.1 0.056 13.1 0.1 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IL17 PF06083.6 OAP63085.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Interleukin-17 NACHT PF05729.7 OAP63085.1 - 0.085 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 OAP63085.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) WD40 PF00400.27 OAP63086.1 - 3.7e-51 169.2 20.1 2.9e-08 33.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 OAP63086.1 - 1.6e-05 24.6 0.0 0.07 12.8 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF423 PF04241.10 OAP63087.1 - 3e-24 84.7 2.2 4.1e-24 84.3 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Epimerase PF01370.16 OAP63088.1 - 8.7e-06 25.3 0.0 1.7e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-MYND PF01753.13 OAP63089.1 - 7.3e-08 32.1 20.1 1.7e-07 31.0 13.9 1.6 1 0 0 1 1 1 1 MYND finger DIOX_N PF14226.1 OAP63090.1 - 2.2e-18 66.8 0.0 3.5e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP63090.1 - 3.5e-14 52.8 0.0 6.7e-14 51.9 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 OAP63091.1 - 1.2e-50 171.7 0.0 1.7e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 OAP63091.1 - 9.3e-25 86.7 0.0 2.9e-24 85.2 0.0 1.9 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 OAP63091.1 - 4.9e-10 39.3 0.5 1.2e-09 38.0 0.1 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 OAP63091.1 - 0.0011 19.1 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain EamA PF00892.15 OAP63092.1 - 2.7e-07 30.6 33.0 1e-06 28.8 4.7 3.1 3 1 1 4 4 4 2 EamA-like transporter family UAA PF08449.6 OAP63092.1 - 6.1e-07 28.6 3.1 1.1e-06 27.8 2.1 1.4 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 OAP63092.1 - 0.00015 21.4 25.6 0.0031 17.1 4.7 2.5 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 OAP63092.1 - 0.00019 21.5 8.6 0.00019 21.5 5.9 3.5 4 1 0 4 4 4 1 Multidrug resistance efflux transporter DUF914 PF06027.7 OAP63092.1 - 0.023 13.5 10.7 0.5 9.1 4.8 3.2 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) RCC1_2 PF13540.1 OAP63093.1 - 6e-12 44.8 8.9 0.00084 18.9 0.0 4.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.28 OAP63093.1 - 1.2e-05 24.7 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain RCC1 PF00415.13 OAP63093.1 - 0.00032 20.8 0.9 0.45 10.7 0.1 4.1 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 OAP63093.1 - 0.074 12.7 0.8 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 F-box-like Ran_BP1 PF00638.13 OAP63094.1 - 6.7e-51 171.4 1.3 1.2e-50 170.6 0.9 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 OAP63094.1 - 6.8e-05 22.5 0.1 0.00049 19.7 0.1 2.1 1 1 0 1 1 1 1 WH1 domain Cwf_Cwc_15 PF04889.7 OAP63094.1 - 0.0089 15.7 11.7 0.015 15.0 8.1 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF1681 PF07933.9 OAP63094.1 - 0.045 13.3 0.9 0.078 12.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1681) CDC27 PF09507.5 OAP63094.1 - 0.071 12.3 23.0 0.092 11.9 15.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 OAP63094.1 - 0.096 11.1 11.4 0.12 10.8 7.9 1.3 1 0 0 1 1 1 0 Daxx Family Nucleo_P87 PF07267.6 OAP63094.1 - 1.9 7.1 8.0 2.5 6.7 5.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 YEATS PF03366.11 OAP63095.1 - 2e-17 62.6 0.0 3.3e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 YEATS family Phosducin PF02114.11 OAP63096.1 - 4e-11 42.1 0.3 9.5e-11 40.9 0.0 1.7 2 0 0 2 2 2 1 Phosducin PTCB-BRCT PF12738.2 OAP63097.1 - 1.4e-44 149.7 0.1 2.9e-19 68.6 0.0 4.4 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 OAP63097.1 - 1.4e-30 105.2 0.0 3.6e-10 39.8 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Arrestin_C PF02752.17 OAP63098.1 - 1.7e-20 73.5 0.0 7.9e-20 71.3 0.0 2.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAP63098.1 - 7.2e-11 42.1 0.0 2.4e-06 27.4 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Mhr1 PF12829.2 OAP63099.1 - 1.1e-26 92.5 0.2 3.4e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination OmpH PF03938.9 OAP63099.1 - 0.0089 15.9 2.5 0.026 14.4 1.7 1.8 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF883 PF05957.8 OAP63099.1 - 5 7.5 7.6 5.9 7.3 0.4 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PH PF00169.24 OAP63100.1 - 5.4e-28 97.2 0.7 1.7e-13 50.7 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 OAP63100.1 - 1.6e-13 50.8 4.5 1.2e-05 25.4 0.5 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 OAP63100.1 - 3.5e-09 36.8 2.1 0.0016 18.5 0.2 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 OAP63100.1 - 1.1e-05 25.2 0.1 0.23 11.3 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_6 PF15406.1 OAP63100.1 - 1.8e-05 24.7 0.1 0.089 12.8 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 OAP63100.1 - 0.00019 21.3 0.8 0.00097 19.0 0.1 2.1 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.1 OAP63100.1 - 0.00079 19.4 0.4 0.3 11.2 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain Glyco_transf_15 PF01793.11 OAP63101.1 - 8e-135 449.0 5.1 1e-134 448.6 3.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase 3H PF02829.9 OAP63102.1 - 0.036 14.0 0.2 0.083 12.9 0.2 1.6 1 0 0 1 1 1 0 3H domain SPT6_acidic PF14632.1 OAP63102.1 - 0.29 11.3 4.4 0.13 12.4 0.3 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Chs3p PF12271.3 OAP63103.1 - 2.5e-133 443.5 14.6 2.9e-133 443.3 10.1 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF1625 PF07787.7 OAP63103.1 - 2.7 7.1 6.8 5.5 6.1 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Lactamase_B_2 PF12706.2 OAP63104.1 - 6.7e-22 77.9 1.6 9.2e-22 77.5 1.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP63104.1 - 2e-14 53.6 0.5 3.6e-14 52.7 0.3 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAP63104.1 - 0.51 9.9 12.2 5.4 6.6 6.8 3.1 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily Cyclin PF08613.6 OAP63105.1 - 1.4e-16 61.2 0.0 2.1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAP63105.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Abhydrolase_5 PF12695.2 OAP63106.1 - 3.5e-06 26.8 0.2 1.7e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP63106.1 - 2.8e-05 24.1 3.1 7.7e-05 22.6 2.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP63106.1 - 0.00016 21.3 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 OAP63106.1 - 0.0049 16.1 0.0 0.011 15.0 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) 4HBT_3 PF13622.1 OAP63108.1 - 3.6e-36 125.2 9.5 5.9e-36 124.5 6.6 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAP63108.1 - 5.8e-07 29.1 0.4 0.024 14.2 0.0 2.5 2 1 0 2 2 2 2 Acyl-CoA thioesterase Tax PF02959.11 OAP63108.1 - 0.095 12.1 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 HTLV Tax Acetyltransf_7 PF13508.1 OAP63109.1 - 3.3e-07 30.3 0.0 1.1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP63109.1 - 2.6e-06 27.3 0.0 3.9e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP63109.1 - 5.7e-06 26.4 0.0 1.2e-05 25.4 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP63109.1 - 6.3e-05 22.8 0.0 0.23 11.3 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP63109.1 - 0.00052 19.7 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 OAP63109.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_N PF08240.7 OAP63110.1 - 1.5e-26 92.2 2.5 2.4e-26 91.6 1.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP63110.1 - 1.1e-17 63.7 0.0 1.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP63110.1 - 0.0012 19.7 0.0 0.0023 18.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 OAP63110.1 - 0.0069 15.9 0.2 0.015 14.8 0.1 1.5 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 OAP63110.1 - 0.041 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF572 PF04502.8 OAP63111.1 - 2.8 7.0 9.7 3.5 6.7 6.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.8 OAP63111.1 - 3.8 7.2 10.1 4.4 7.0 7.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.6 OAP63112.1 - 0.32 9.6 1.4 0.37 9.4 1.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Arrestin_C PF02752.17 OAP63113.1 - 2.5e-15 56.7 0.1 1e-14 54.8 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 OAP63114.1 - 4.1e-43 147.2 0.0 4.8e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_1 PF00018.23 OAP63115.1 - 1.9e-05 23.9 0.0 3.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAP63115.1 - 0.0069 15.9 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 OAP63116.1 - 4.6e-43 147.2 0.0 7.5e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63116.1 - 2.5e-25 89.0 0.0 5.9e-19 68.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Methyltransf_25 PF13649.1 OAP63117.1 - 3.2e-06 27.4 0.3 6.8e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP63117.1 - 0.045 13.3 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAP63117.1 - 0.088 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 OAP63119.1 - 1.3e-62 211.8 0.0 6.3e-62 209.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Tad PF13400.1 OAP63119.1 - 0.088 12.8 1.2 0.2 11.7 0.9 1.6 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Fungal_trans_2 PF11951.3 OAP63120.1 - 0.027 13.0 0.6 0.1 11.1 0.2 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain Presenilin PF01080.12 OAP63121.1 - 8.6 5.0 5.9 8.8 5.0 3.5 1.4 1 1 0 1 1 1 0 Presenilin AA_permease_2 PF13520.1 OAP63122.1 - 8e-46 156.4 60.2 1e-45 156.0 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP63122.1 - 4.2e-30 104.5 52.2 5.7e-30 104.0 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.11 OAP63123.1 - 2.5e-41 142.0 0.0 3.8e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 OAP63123.1 - 3.1e-05 24.3 0.2 0.00019 21.8 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 OAP63123.1 - 0.015 15.7 0.4 5.6 7.5 0.0 2.7 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily Mei5 PF10376.4 OAP63124.1 - 0.29 10.6 3.5 0.19 11.2 0.5 1.8 2 0 0 2 2 2 0 Double-strand recombination repair protein Actin PF00022.14 OAP63125.1 - 9.4e-16 57.2 0.0 1e-13 50.5 0.0 2.8 2 1 0 2 2 2 2 Actin XPG_I PF00867.13 OAP63126.1 - 2.8e-25 88.1 0.0 5e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 OAP63126.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing FolB PF02152.13 OAP63127.1 - 5.6e-28 97.3 0.1 1.8e-19 69.9 0.5 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.20 OAP63128.1 - 2.7e-60 203.7 0.0 3.7e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63128.1 - 1.7e-27 96.1 0.0 2.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAP63128.1 - 0.0017 18.8 0.6 0.028 14.9 0.0 2.8 2 1 0 2 2 2 1 Protein kinase C terminal domain Corona_nucleoca PF00937.13 OAP63128.1 - 0.98 8.2 5.7 0.31 9.9 1.6 1.8 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein F-box-like PF12937.2 OAP63129.1 - 0.033 13.9 0.9 0.27 10.9 0.0 2.8 3 0 0 3 3 3 0 F-box-like WSC PF01822.14 OAP63130.1 - 7.2e-07 29.0 5.9 7.2e-07 29.0 4.1 2.4 2 0 0 2 2 2 1 WSC domain FlgH PF02107.11 OAP63130.1 - 2 7.9 6.3 0.22 11.0 0.7 1.9 2 0 0 2 2 2 0 Flagellar L-ring protein DUF2124 PF09897.4 OAP63131.1 - 0.073 12.7 0.8 5.4 6.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2124) Inhibitor_I53 PF11714.3 OAP63132.1 - 0.36 10.8 4.3 1.5 8.8 3.0 2.1 1 0 0 1 1 1 0 Thrombin inhibitor Madanin SDA1 PF05285.7 OAP63132.1 - 0.59 9.3 5.1 0.73 9.0 3.5 1.1 1 0 0 1 1 1 0 SDA1 PAN_1 PF00024.21 OAP63133.1 - 0.0012 18.5 2.2 0.0026 17.4 0.0 2.5 3 0 0 3 3 3 1 PAN domain MFS_1 PF07690.11 OAP63134.1 - 1.4e-29 102.9 40.3 2.8e-26 92.0 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 OAP63134.1 - 0.049 13.6 0.1 0.049 13.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF2158 PF09926.4 OAP63135.1 - 0.025 13.9 0.2 0.062 12.7 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) HMG_box PF00505.14 OAP63136.1 - 1.8e-24 85.7 2.1 3.3e-24 84.9 1.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAP63136.1 - 1.2e-19 70.3 2.6 2.3e-19 69.5 1.8 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 OAP63136.1 - 0.00031 20.4 0.9 0.0008 19.1 0.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box 5 YABBY PF04690.8 OAP63136.1 - 0.024 14.8 1.1 0.027 14.7 0.5 1.3 1 1 0 1 1 1 0 YABBY protein DUF1014 PF06244.7 OAP63136.1 - 0.038 14.1 0.2 0.038 14.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) TPPII_N PF12583.3 OAP63136.1 - 0.045 13.8 4.3 0.064 13.3 3.0 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal ATG11 PF10377.4 OAP63137.1 - 3.7e-41 140.0 2.8 1.5e-40 138.1 0.0 3.2 2 0 0 2 2 2 1 Autophagy-related protein 11 DUF3445 PF11927.3 OAP63138.1 - 1.2e-78 263.9 0.0 1.5e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Oxidored_q1_N PF00662.15 OAP63138.1 - 0.46 10.0 1.9 1 8.9 1.3 1.5 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus PY_rept_46 PF09689.5 OAP63138.1 - 1.3 9.3 0.0 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 Plasmodium yoelii repeat (PY_rept_46) Homoserine_dh PF00742.14 OAP63139.1 - 7.2e-53 178.9 0.0 9.3e-53 178.5 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 OAP63139.1 - 9.4e-13 48.5 0.0 1.8e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CAP_GLY PF01302.20 OAP63139.1 - 0.084 12.5 0.3 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 CAP-Gly domain TSKS PF15358.1 OAP63140.1 - 0.16 10.1 0.3 0.24 9.5 0.2 1.2 1 0 0 1 1 1 0 Testis-specific serine kinase substrate AJAP1_PANP_C PF15298.1 OAP63141.1 - 0.00082 19.3 0.6 0.0012 18.7 0.4 1.2 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Herpes_gE PF02480.11 OAP63141.1 - 0.0052 15.1 0.0 0.0061 14.8 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E NPDC1 PF06809.6 OAP63141.1 - 0.0076 15.0 0.9 0.013 14.3 0.6 1.3 1 1 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) CD34_antigen PF06365.7 OAP63141.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.1 OAP63141.1 - 0.013 15.1 0.0 0.021 14.5 0.0 1.4 1 1 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.1 OAP63141.1 - 0.032 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1180 PF06679.7 OAP63141.1 - 0.062 13.1 1.2 0.096 12.5 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3609 PF12259.3 OAP63141.1 - 0.09 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) EphA2_TM PF14575.1 OAP63141.1 - 0.12 12.7 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4215 PF13948.1 OAP63142.1 - 0.00023 21.2 8.1 0.00023 21.2 5.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) MAD PF05557.8 OAP63144.1 - 6.3e-57 193.1 55.5 1.1e-56 192.3 38.5 1.4 1 0 0 1 1 1 1 Mitotic checkpoint protein Reo_sigmaC PF04582.7 OAP63144.1 - 0.00079 18.6 23.9 0.0019 17.4 2.5 3.7 3 1 0 3 3 3 3 Reovirus sigma C capsid protein Fib_alpha PF08702.5 OAP63144.1 - 0.00099 19.2 3.7 0.00099 19.2 2.6 5.5 3 3 2 5 5 5 1 Fibrinogen alpha/beta chain family Rootletin PF15035.1 OAP63144.1 - 0.0018 18.2 7.0 0.0018 18.2 4.8 5.4 1 1 4 5 5 5 1 Ciliary rootlet component, centrosome cohesion Fungal_trans_2 PF11951.3 OAP63145.1 - 0.0046 15.5 0.3 0.03 12.9 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Metal_resist PF13801.1 OAP63146.1 - 0.07 13.1 0.2 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Heavy-metal resistance zf-C2H2 PF00096.21 OAP63149.1 - 2.3e-09 37.0 15.0 0.00026 21.1 0.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP63149.1 - 7.4e-07 29.0 15.8 0.0021 18.2 0.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.10 OAP63149.1 - 0.11 12.2 1.5 0.25 11.1 1.0 1.6 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.7 OAP63149.1 - 1.5 9.0 7.7 1.6 8.9 1.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Histone PF00125.19 OAP63150.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 OAP63150.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 OAP63150.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAP63150.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAP63150.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 OAP63150.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 OAP63151.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAP63151.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAP63151.1 - 0.0042 17.0 0.4 0.0073 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAP63151.1 - 0.039 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Mpv17_PMP22 PF04117.7 OAP63152.1 - 3.7e-16 58.5 1.1 7.9e-16 57.4 0.8 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Exo5 PF09810.4 OAP63153.1 - 9e-115 383.3 0.0 2.3e-114 381.9 0.0 1.6 2 0 0 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 OAP63153.1 - 6.2e-07 29.0 0.6 8.7e-06 25.2 0.0 2.8 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF3445 PF11927.3 OAP63154.1 - 1e-80 270.7 0.0 1.7e-80 270.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.12 OAP63155.1 - 3.2e-88 296.5 20.2 3.7e-88 296.3 14.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 OAP63155.1 - 0.0063 16.4 9.0 0.0063 16.4 6.3 2.4 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase EHN PF06441.7 OAP63158.1 - 2.8e-30 104.4 0.3 6.5e-30 103.3 0.1 1.6 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAP63158.1 - 4.1e-06 26.8 0.0 6.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family tRNA_bind_2 PF13725.1 OAP63158.1 - 0.0097 15.9 0.0 6.5 6.9 0.0 2.4 2 0 0 2 2 2 2 Possible tRNA binding domain FPN1 PF06963.7 OAP63159.1 - 6.7e-126 420.1 18.2 7.8e-126 419.9 12.6 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Gar1 PF04410.9 OAP63160.1 - 2.2e-43 147.3 0.7 2.2e-43 147.3 0.5 2.5 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region EPSP_synthase PF00275.15 OAP63161.1 - 6.7e-129 429.9 0.0 2e-128 428.3 0.0 1.8 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 OAP63161.1 - 2.7e-96 321.5 0.0 4.7e-96 320.7 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 OAP63161.1 - 3.2e-59 200.3 0.0 8e-59 199.0 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 OAP63161.1 - 9.5e-38 129.5 1.0 6.8e-37 126.7 0.0 2.8 4 0 0 4 4 4 1 Shikimate kinase Shikimate_dh_N PF08501.6 OAP63161.1 - 1.1e-24 86.2 0.0 2.6e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.1 OAP63161.1 - 4.7e-10 39.2 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.15 OAP63161.1 - 1.8e-08 34.5 0.0 5.5e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 OAP63161.1 - 0.005 17.6 0.0 0.014 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain MAF_flag10 PF01973.13 OAP63161.1 - 0.021 14.3 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF115 AAA_33 PF13671.1 OAP63161.1 - 0.021 14.6 0.0 0.23 11.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain MOSC_N PF03476.11 OAP63162.1 - 2.2e-15 56.3 0.0 4.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 OAP63162.1 - 9e-12 44.6 0.1 5.5e-11 42.0 0.0 2.3 2 1 0 2 2 2 1 MOSC domain Epimerase PF01370.16 OAP63163.1 - 9e-12 44.9 0.0 1.9e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP63163.1 - 1.1e-05 24.2 0.0 0.00013 20.7 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP63163.1 - 9.8e-05 22.4 0.1 0.00014 21.8 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP63163.1 - 0.00033 19.9 0.1 0.00048 19.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 OAP63163.1 - 0.0007 19.5 0.4 0.0038 17.1 0.2 2.2 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.10 OAP63163.1 - 0.0029 17.4 0.1 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 OAP63163.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 OAP63163.1 - 0.0087 16.1 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.21 OAP63163.1 - 0.0089 15.5 0.1 0.02 14.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 OAP63163.1 - 0.013 15.1 0.2 0.019 14.6 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAP63163.1 - 0.041 14.3 0.1 0.14 12.5 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 OAP63163.1 - 0.11 11.6 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.19 OAP63164.1 - 1.8e-70 237.7 21.1 2.1e-70 237.5 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63164.1 - 8.6e-13 47.7 31.3 1e-09 37.5 6.5 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP63164.1 - 4.2e-07 28.7 20.5 2.9e-05 22.6 3.4 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein RuvB_C PF05491.8 OAP63164.1 - 0.11 12.0 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB C-terminus Lipase_GDSL_2 PF13472.1 OAP63165.1 - 1.3e-22 80.8 1.6 2.3e-22 79.9 1.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 OAP63165.1 - 1.7e-18 67.2 0.0 2.1e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fungal_trans PF04082.13 OAP63166.1 - 1.6e-29 102.5 0.0 2.9e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.1 OAP63167.1 - 2.3e-19 69.3 0.1 6.7e-18 64.6 0.0 2.7 3 0 0 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 OAP63167.1 - 5.8e-14 52.3 2.9 1.2e-13 51.3 0.1 2.6 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 OAP63167.1 - 1.9e-05 24.6 0.0 4.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 OAP63167.1 - 0.00017 20.6 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Glyco_hyd_65N_2 PF14498.1 OAP63168.1 - 9.8e-37 126.8 0.0 1.6e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 OAP63168.1 - 0.0027 16.4 0.0 0.0044 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain COX2-transmemb PF09125.5 OAP63169.1 - 1.5 8.4 5.8 0.24 10.9 0.3 2.4 2 1 1 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane Ribosomal_S2 PF00318.15 OAP63170.1 - 5.5e-44 149.9 0.0 4.2e-23 81.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 OAP63171.1 - 8.6e-18 63.8 0.8 1.4e-17 63.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 RRXRR PF14239.1 OAP63171.1 - 1.5 8.2 7.3 0.64 9.4 0.6 2.8 2 1 1 3 3 3 0 RRXRR protein adh_short_C2 PF13561.1 OAP63172.1 - 3e-25 89.3 0.0 3.6e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP63172.1 - 1.3e-24 87.0 0.0 2.5e-24 86.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP63172.1 - 4.7e-09 36.1 0.0 1.3e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 OAP63172.1 - 1.6e-06 27.7 0.2 3.8e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP63172.1 - 0.002 18.1 0.4 0.004 17.1 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP63172.1 - 0.0029 16.3 0.0 0.0043 15.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 OAP63172.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 OAP63172.1 - 0.017 14.8 0.5 0.037 13.8 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 OAP63172.1 - 0.031 13.3 0.1 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.12 OAP63172.1 - 0.069 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.13 OAP63172.1 - 0.1 12.5 0.3 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 OAP63172.1 - 0.13 11.4 0.1 0.27 10.3 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 OAP63172.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 OAP63173.1 - 7.8e-22 78.2 0.2 1.4e-21 77.4 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP63173.1 - 4.8e-11 42.6 0.0 7.7e-10 38.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP63173.1 - 1.6e-05 24.6 0.0 5.2e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAP63173.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase NmrA PF05368.8 OAP63174.1 - 5.3e-17 61.8 0.0 7.1e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP63174.1 - 4e-12 46.5 0.8 7.5e-12 45.6 0.6 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP63174.1 - 0.00028 20.3 0.1 0.00042 19.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 OAP63174.1 - 0.00035 20.4 0.1 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 OAP63174.1 - 0.00098 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.11 OAP63174.1 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 OAP63174.1 - 0.0051 17.2 1.0 0.0093 16.3 0.2 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 OAP63174.1 - 0.0056 15.4 0.0 0.0092 14.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 OAP63174.1 - 0.0076 16.2 0.3 0.016 15.2 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 OAP63174.1 - 0.015 15.1 0.2 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 OAP63174.1 - 0.019 14.6 0.2 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 OAP63174.1 - 0.035 12.9 0.2 0.059 12.2 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GFO_IDH_MocA PF01408.17 OAP63174.1 - 0.05 14.1 0.1 0.087 13.3 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ldh_1_N PF00056.18 OAP63174.1 - 0.076 12.8 0.4 0.13 12.0 0.3 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF2196 PF09962.4 OAP63176.1 - 6.4e-23 80.3 1.9 1.1e-22 79.5 1.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) TFIIA PF03153.8 OAP63176.1 - 0.76 9.6 23.7 0.88 9.3 16.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 OAP63176.1 - 0.76 7.9 32.4 0.81 7.8 22.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 OAP63176.1 - 2.4 7.4 26.2 2.8 7.2 18.1 1.1 1 0 0 1 1 1 0 Vta1 like Neur_chan_memb PF02932.11 OAP63176.1 - 5.4 6.8 6.2 7.1 6.4 4.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.17 OAP63177.1 - 1.1e-10 41.1 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ras family CYSTM PF12734.2 OAP63178.1 - 3.5e-09 36.5 5.7 3.5e-09 36.5 4.0 4.5 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance Pkinase PF00069.20 OAP63179.1 - 8.9e-62 208.5 0.0 1.2e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63179.1 - 4.8e-33 114.3 0.0 5.7e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP63179.1 - 2e-05 23.7 0.0 8e-05 21.7 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 OAP63179.1 - 0.00069 19.4 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAP63179.1 - 0.023 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 OAP63179.1 - 0.037 12.8 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 OAP63179.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LIP PF03583.9 OAP63180.1 - 6e-71 239.0 0.1 8.4e-71 238.5 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Amidohydro_1 PF01979.15 OAP63181.1 - 1.1e-31 110.7 0.8 1.4e-31 110.4 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAP63181.1 - 7.7e-13 49.0 2.8 9.7e-11 42.2 1.9 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP63181.1 - 1.6e-09 37.5 0.7 1.3e-06 27.8 0.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP63181.1 - 3.9e-06 26.5 0.8 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase DJ-1_PfpI PF01965.19 OAP63181.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family DUF1275 PF06912.6 OAP63182.1 - 4.5e-39 133.8 8.1 5.5e-39 133.5 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1686 PF07937.6 OAP63182.1 - 0.026 14.1 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) MBOAT_2 PF13813.1 OAP63182.1 - 0.13 12.3 1.3 6.8 6.8 0.0 3.3 2 1 0 3 3 3 0 Membrane bound O-acyl transferase family PGM_PMM_I PF02878.11 OAP63183.1 - 9.8e-31 106.0 0.0 1.5e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 OAP63183.1 - 3.1e-23 81.9 0.0 5.3e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 OAP63183.1 - 3.5e-15 56.1 0.0 8.5e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 OAP63183.1 - 4.9e-09 36.0 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 OAP63185.1 - 7.8e-14 52.2 0.0 9.1e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease SWIB PF02201.13 OAP63186.1 - 4.1e-14 52.0 0.0 9.8e-14 50.8 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain OmdA PF13376.1 OAP63186.1 - 0.034 13.7 0.3 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated His_Phos_1 PF00300.17 OAP63187.1 - 5.5e-32 111.0 0.1 3e-31 108.6 0.1 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 OAP63187.1 - 0.0018 17.6 0.0 0.004 16.5 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Dor1 PF04124.7 OAP63188.1 - 3.3e-45 154.0 0.4 5.1e-33 113.9 0.5 2.3 2 0 0 2 2 2 2 Dor1-like family SHS2_Rpb7-N PF03876.12 OAP63190.1 - 2.6e-12 46.6 0.0 3.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 OAP63190.1 - 2.6e-06 27.4 0.0 4.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain Fungal_trans PF04082.13 OAP63192.1 - 7.8e-17 61.0 0.1 7.8e-17 61.0 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63192.1 - 6.1e-07 29.2 12.2 9.7e-07 28.5 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 OAP63192.1 - 0.14 11.7 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Na_Ca_ex PF01699.19 OAP63193.1 - 5.3e-25 87.6 20.0 4.8e-14 52.1 4.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 OAP63193.1 - 0.11 12.3 0.2 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) PIP5K PF01504.13 OAP63194.1 - 7.8e-81 270.8 0.0 1.4e-80 270.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pmp3 PF01679.12 OAP63195.1 - 1.2e-22 79.3 4.7 1.4e-22 79.1 3.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RseC_MucC PF04246.7 OAP63195.1 - 0.18 11.3 0.4 0.21 11.1 0.3 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC EMG1 PF03587.9 OAP63196.1 - 4.5e-79 264.4 0.0 5.3e-79 264.2 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyoxalase_2 PF12681.2 OAP63197.1 - 5.3e-06 26.9 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAP63197.1 - 0.067 13.1 0.0 0.067 13.1 0.0 2.9 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ada_Zn_binding PF02805.11 OAP63198.1 - 2.1e-27 94.4 5.7 4.1e-27 93.5 4.0 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.2 OAP63198.1 - 0.0013 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.18 OAP63198.1 - 0.0043 16.8 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Glyco_transf_90 PF05686.7 OAP63199.1 - 5.3e-13 48.4 0.2 3.9e-09 35.6 0.1 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 GNAT_acetyltr_2 PF13718.1 OAP63200.1 - 3.4e-81 271.2 0.0 6.5e-81 270.3 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 OAP63200.1 - 3.1e-66 222.3 0.0 1.1e-65 220.6 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 OAP63200.1 - 1.1e-39 134.0 0.1 2.7e-39 132.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 OAP63200.1 - 2.6e-35 120.5 1.3 7.2e-35 119.1 0.9 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 OAP63200.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2796 PF10986.3 OAP63200.1 - 1.6 8.6 4.0 1.1 9.2 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Thioredoxin PF00085.15 OAP63202.1 - 1.5e-29 101.6 0.0 3.9e-25 87.5 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 OAP63202.1 - 5.6e-07 29.5 0.0 1.4e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 OAP63202.1 - 5.9e-06 26.4 0.1 0.00082 19.5 0.1 2.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAP63202.1 - 0.00034 20.6 0.0 0.059 13.5 0.0 3.6 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 OAP63202.1 - 0.0066 16.4 0.1 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 OAP63202.1 - 0.01 15.4 0.0 0.077 12.6 0.0 2.3 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_3 PF13192.1 OAP63202.1 - 0.046 13.5 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Zn_clus PF00172.13 OAP63203.1 - 0.00013 21.7 5.0 0.00013 21.7 3.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3752 PF12572.3 OAP63204.1 - 2e-27 96.1 12.6 3.4e-17 62.9 2.9 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3752) Cut8_N PF14482.1 OAP63204.1 - 0.0058 16.6 1.8 0.0058 16.6 1.2 2.5 2 1 0 2 2 2 1 Cut8 proteasome-binding domain Pro_isomerase PF00160.16 OAP63206.1 - 2.7e-43 147.8 0.1 3.1e-43 147.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Epimerase PF01370.16 OAP63208.1 - 3.5e-11 43.0 0.0 5.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP63208.1 - 6.8e-11 41.3 0.0 1.1e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAP63208.1 - 5.2e-06 26.5 0.2 2e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP63208.1 - 2.5e-05 23.3 0.0 0.0038 16.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 OAP63208.1 - 0.00097 18.4 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family FAD_binding_2 PF00890.19 OAP63209.1 - 4.2e-82 276.2 0.4 5.2e-82 275.9 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 OAP63209.1 - 9.3e-21 73.4 2.2 1.2e-18 66.7 0.1 3.7 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 OAP63209.1 - 1.1e-13 50.8 0.5 1.2e-12 47.4 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP63209.1 - 1.7e-09 37.5 2.2 3e-08 33.5 0.1 3.3 3 1 1 4 4 4 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 OAP63209.1 - 8.4e-09 34.9 0.1 3.3e-08 33.0 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP63209.1 - 7.3e-05 21.4 2.3 0.00026 19.5 0.3 2.6 2 1 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 OAP63209.1 - 0.0001 22.2 0.1 0.0029 17.5 0.1 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP63209.1 - 0.00028 20.0 0.3 0.015 14.3 0.0 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 OAP63209.1 - 0.00042 19.2 1.3 0.13 11.1 0.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 OAP63209.1 - 0.0019 17.3 0.3 1.6 7.6 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 OAP63209.1 - 0.0025 17.9 0.0 0.0061 16.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP63209.1 - 0.0075 15.3 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.13 OAP63209.1 - 0.05 11.9 0.1 0.079 11.2 0.1 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.22 OAP63209.1 - 0.08 13.3 0.2 1.7 9.1 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4341 PF14241.1 OAP63209.1 - 1.7 8.3 6.4 3.1 7.5 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4341) TFIIS_M PF07500.9 OAP63210.1 - 1.6e-26 92.5 0.5 2.9e-26 91.7 0.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 OAP63210.1 - 4.4e-19 67.8 5.4 7.9e-19 67.0 3.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 OAP63210.1 - 6.1e-13 48.0 0.1 1.2e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Cytochrome_C554 PF13435.1 OAP63210.1 - 0.0035 17.3 7.0 0.0078 16.2 4.9 1.5 1 0 0 1 1 1 1 Cytochrome c554 and c-prime Chordopox_A33R PF05966.7 OAP63210.1 - 0.043 12.5 2.5 0.35 9.6 0.0 2.3 1 1 1 2 2 2 0 Chordopoxvirus A33R protein Borrelia_REV PF03978.8 OAP63210.1 - 0.065 12.9 1.2 0.1 12.3 0.8 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Cytochrome_C7 PF14522.1 OAP63210.1 - 0.14 11.7 4.2 0.29 10.7 2.9 1.6 1 0 0 1 1 1 0 Cytochrome c7 Cytochrom_NNT PF03264.9 OAP63210.1 - 0.26 10.6 7.1 0.45 9.9 4.9 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Acetyltransf_1 PF00583.19 OAP63211.1 - 7.3e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP63211.1 - 0.0005 20.1 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP63211.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 OAP63211.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CorA PF01544.13 OAP63212.1 - 1.6e-05 24.1 0.0 6e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ZYG-11_interact PF05884.7 OAP63212.1 - 0.31 10.0 0.0 0.57 9.2 0.0 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 APC_CDC26 PF10471.4 OAP63213.1 - 4.4e-14 52.9 0.0 9.5e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 VWA_2 PF13519.1 OAP63214.1 - 2.5e-12 47.2 0.0 4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 OAP63214.1 - 1.3e-05 24.9 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 OAP63214.1 - 0.00025 20.8 0.1 0.00037 20.2 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Salt_tol_Pase PF09506.5 OAP63214.1 - 0.0058 15.2 0.0 0.0085 14.6 0.0 1.1 1 0 0 1 1 1 1 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) UIM PF02809.15 OAP63214.1 - 0.013 15.0 2.8 0.047 13.2 2.0 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Phage_Gp23 PF10669.4 OAP63214.1 - 0.94 9.6 4.8 1.8 8.6 3.3 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Sybindin PF04099.7 OAP63215.1 - 1.4e-35 122.1 0.0 2.1e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family HNH_2 PF13391.1 OAP63215.1 - 2.5e-15 56.0 0.0 6.4e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Sedlin_N PF04628.8 OAP63215.1 - 0.00034 20.4 0.0 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Fungal_trans PF04082.13 OAP63216.1 - 5.9e-13 48.2 0.8 8.7e-13 47.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63216.1 - 1.2e-05 25.0 9.3 2.3e-05 24.2 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF59 PF01883.14 OAP63217.1 - 7.6e-06 25.8 0.1 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Pheromone PF08015.6 OAP63217.1 - 1.3 9.9 5.4 4.4 8.2 0.0 2.7 2 1 0 2 2 2 0 Fungal mating-type pheromone Sugar_tr PF00083.19 OAP63218.1 - 1.9e-16 59.7 25.6 9.8e-10 37.5 5.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TMEM213 PF15192.1 OAP63218.1 - 4 7.5 6.0 12 6.0 1.2 2.5 2 0 0 2 2 2 0 TMEM213 family Ph1570 PF09638.5 OAP63219.1 - 0.094 12.5 0.1 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Ph1570 protein Pkinase PF00069.20 OAP63220.1 - 9e-59 198.7 0.0 1.4e-58 198.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63220.1 - 5.1e-40 137.1 0.0 7.8e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP63220.1 - 1e-05 24.6 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAP63220.1 - 0.0013 17.8 0.0 0.0029 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP63220.1 - 0.0048 16.6 0.8 0.0048 16.6 0.6 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 OAP63220.1 - 0.0093 15.3 0.0 0.0093 15.3 0.0 1.7 2 0 0 2 2 2 1 RIO1 family OB_NTP_bind PF07717.11 OAP63221.1 - 2.6e-25 88.4 0.0 6e-24 84.0 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAP63221.1 - 5.2e-25 87.4 1.2 1.3e-24 86.1 0.0 2.4 3 0 0 3 3 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAP63221.1 - 9e-13 47.8 0.0 2.5e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP63221.1 - 1.8e-07 30.8 0.1 4.6e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAP63221.1 - 7.9e-05 22.8 0.1 0.0003 20.9 0.1 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAP63221.1 - 0.00023 20.1 0.0 0.0006 18.7 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein SRP54 PF00448.17 OAP63221.1 - 0.00044 19.7 0.2 0.0012 18.3 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 OAP63221.1 - 0.00066 19.5 0.0 0.31 10.8 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 OAP63221.1 - 0.003 17.4 0.3 0.027 14.3 0.2 2.4 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 OAP63221.1 - 0.007 16.1 0.1 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.4 OAP63221.1 - 0.01 14.8 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 OAP63221.1 - 0.013 15.1 1.2 0.53 9.9 0.2 3.0 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.17 OAP63221.1 - 0.015 14.1 0.1 0.027 13.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 OAP63221.1 - 0.028 14.1 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase KaiC PF06745.8 OAP63221.1 - 0.035 13.2 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC Glug PF07581.7 OAP63221.1 - 0.14 12.3 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 The GLUG motif AAA_23 PF13476.1 OAP63221.1 - 0.38 11.0 2.5 0.83 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 OAP63221.1 - 0.43 11.4 2.9 0.72 10.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 OAP63221.1 - 1.6 9.0 5.1 0.52 10.6 0.3 2.6 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 OAP63221.1 - 2.5 6.7 7.9 0.092 11.4 0.2 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Prefoldin_2 PF01920.15 OAP63222.1 - 3.1e-23 81.5 9.6 3.7e-23 81.2 6.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tho2 PF11262.3 OAP63222.1 - 0.0056 15.7 1.8 0.05 12.6 0.0 1.9 1 1 1 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Spuma_A9PTase PF03539.9 OAP63222.1 - 0.0086 16.0 2.0 0.011 15.6 0.1 1.8 1 1 1 2 2 2 1 Spumavirus aspartic protease (A9) Prefoldin PF02996.12 OAP63222.1 - 0.0097 15.5 7.3 1.4 8.5 5.1 2.3 1 1 0 1 1 1 1 Prefoldin subunit Baculo_PEP_C PF04513.7 OAP63222.1 - 0.01 15.6 0.5 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UBN2 PF14223.1 OAP63222.1 - 0.014 15.1 1.9 0.068 12.9 0.2 2.3 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type V_ATPase_I PF01496.14 OAP63222.1 - 0.056 11.3 1.8 0.072 10.9 0.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 OAP63222.1 - 0.14 12.1 5.4 0.17 11.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) PhageMin_Tail PF10145.4 OAP63222.1 - 0.14 11.7 0.6 0.17 11.4 0.4 1.1 1 0 0 1 1 1 0 Phage-related minor tail protein FliJ PF02050.11 OAP63222.1 - 0.18 11.8 11.3 0.12 12.4 1.8 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 OAP63222.1 - 0.33 10.6 9.4 1.9 8.2 0.8 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 OAP63222.1 - 0.41 10.3 10.7 0.13 11.9 1.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DASH_Dad3 PF08656.5 OAP63222.1 - 0.46 10.2 5.6 0.43 10.2 1.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 Erp_C PF06780.6 OAP63222.1 - 0.54 10.0 5.6 0.95 9.2 0.1 2.1 1 1 1 2 2 2 0 Erp protein C-terminus WXG100 PF06013.7 OAP63222.1 - 0.59 10.1 4.0 1.5 8.9 0.6 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 OAP63222.1 - 0.65 10.4 5.1 2.2 8.7 0.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2205 PF10224.4 OAP63222.1 - 0.71 9.4 6.7 0.16 11.5 0.7 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4559 PF15112.1 OAP63222.1 - 0.88 8.6 8.1 0.54 9.3 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) FlaC_arch PF05377.6 OAP63222.1 - 0.94 9.4 3.4 2.6 8.0 0.4 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 OAP63222.1 - 1.1 9.3 8.5 2.8 8.0 5.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 OAP63222.1 - 1.1 9.1 3.6 3.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.5 OAP63222.1 - 1.4 9.0 7.6 0.46 10.5 0.6 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil IncA PF04156.9 OAP63222.1 - 2.3 7.7 10.1 6.1 6.3 7.0 1.6 1 1 0 1 1 1 0 IncA protein DUF904 PF06005.7 OAP63222.1 - 2.4 8.4 8.7 7 7.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Tup_N PF08581.5 OAP63222.1 - 2.6 8.2 7.9 12 6.2 1.6 2.2 2 0 0 2 2 2 0 Tup N-terminal Sulfate_transp PF00916.15 OAP63225.1 - 1.9e-48 164.9 6.9 3.8e-48 163.8 4.8 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 OAP63225.1 - 8.5e-26 89.4 2.8 8.5e-26 89.4 1.9 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 OAP63225.1 - 4.4e-06 26.0 0.0 9.7e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 STAS domain DUF1843 PF08898.5 OAP63225.1 - 0.15 12.1 0.1 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Aldose_epim PF01263.15 OAP63227.1 - 1.3e-53 182.0 0.5 1.8e-53 181.6 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Sds3 PF08598.6 OAP63228.1 - 2e-40 138.5 19.5 1e-39 136.2 13.5 2.0 1 1 0 1 1 1 1 Sds3-like Amidohydro_1 PF01979.15 OAP63229.1 - 1.3e-12 48.0 1.7 1.4e-06 28.2 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 OAP63229.1 - 4.1e-12 46.7 5.2 3.3e-11 43.7 3.6 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 OAP63229.1 - 4.7e-09 35.9 1.5 1.1e-08 34.7 0.3 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP63229.1 - 3.8e-07 29.6 2.6 8.4e-05 21.9 0.4 2.7 2 1 0 2 2 2 2 Amidohydrolase family M-inducer_phosp PF06617.8 OAP63230.1 - 0.65 9.0 3.4 1.1 8.2 2.3 1.3 1 0 0 1 1 1 0 M-phase inducer phosphatase Methyltransf_2 PF00891.13 OAP63231.1 - 2e-32 112.3 0.0 2.8e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Grp1_Fun34_YaaH PF01184.14 OAP63233.1 - 3.2e-27 95.2 19.6 4.4e-27 94.7 13.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1212 PF06738.7 OAP63236.1 - 1 8.8 9.3 1.7 8.0 6.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) Thioredoxin_4 PF13462.1 OAP63237.1 - 1.1e-10 41.7 0.0 2.4e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 OAP63237.1 - 0.11 12.0 0.5 0.23 10.9 0.1 1.8 2 1 0 2 2 2 0 DSBA-like thioredoxin domain CKS PF01111.14 OAP63238.1 - 2.5e-34 116.9 0.9 3.6e-34 116.3 0.1 1.5 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.20 OAP63239.1 - 1.2e-39 134.1 6.7 1.4e-19 69.7 0.4 2.3 2 0 0 2 2 2 2 Bromodomain Mucin PF01456.12 OAP63239.1 - 0.0071 16.1 12.0 0.019 14.7 8.3 1.7 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3844 PF12955.2 OAP63240.1 - 1e-35 121.9 6.0 1.5e-35 121.3 4.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 OAP63240.1 - 0.22 11.7 11.5 0.52 10.5 7.9 1.6 1 0 0 1 1 1 0 EGF-like domain NAGidase PF07555.8 OAP63241.1 - 0.049 12.5 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase TPT PF03151.11 OAP63242.1 - 8.3e-07 28.7 6.8 9.3e-07 28.6 0.5 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 OAP63242.1 - 0.011 15.8 0.1 0.011 15.8 0.1 3.8 4 1 1 5 5 5 0 EamA-like transporter family RRF PF01765.14 OAP63243.1 - 1.9e-25 89.2 1.6 1.1e-24 86.7 1.1 2.0 1 1 0 1 1 1 1 Ribosome recycling factor DUF1310 PF07006.6 OAP63243.1 - 0.16 11.4 0.6 0.33 10.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) ATP-synt_B PF00430.13 OAP63243.1 - 0.56 10.0 6.2 0.92 9.3 3.4 2.0 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) DUF3391 PF11871.3 OAP63243.1 - 2.9 8.1 6.7 0.44 10.7 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) HSP70 PF00012.15 OAP63244.1 - 7.7e-215 714.3 16.6 4.6e-197 655.6 2.1 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 OAP63244.1 - 7.7e-16 57.5 0.3 1.4e-14 53.4 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 OAP63244.1 - 0.00023 20.8 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2408 PF10303.4 OAP63244.1 - 0.15 12.1 1.2 0.26 11.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) FtsA PF14450.1 OAP63244.1 - 0.41 10.4 7.3 1 9.2 0.1 3.8 3 2 0 3 3 3 0 Cell division protein FtsA RTA1 PF04479.8 OAP63245.1 - 4.9e-47 160.3 6.0 4.9e-47 160.3 4.2 1.4 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.3 OAP63246.1 - 0.00044 18.9 0.0 0.00079 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.22 OAP63247.1 - 5.6e-45 153.0 0.0 8.1e-45 152.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAP63247.1 - 6.7e-26 90.2 0.0 2.4e-25 88.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 OAP63247.1 - 2e-16 59.6 0.0 6.1e-16 58.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAP63247.1 - 1.8e-07 31.1 0.0 7.2e-07 29.2 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 OAP63247.1 - 8.7e-07 28.7 0.1 3.3e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 OAP63247.1 - 9.5e-05 22.8 0.1 0.00027 21.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAP63247.1 - 0.00014 21.8 0.1 0.00025 20.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 OAP63247.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Ras family Thiolase_N PF00108.18 OAP63248.1 - 2.1e-97 325.2 0.1 3.9e-97 324.3 0.0 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAP63248.1 - 4.1e-45 152.1 2.0 1.2e-44 150.6 1.4 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAP63248.1 - 2.4e-05 23.9 2.1 5.8e-05 22.6 0.8 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 OAP63248.1 - 0.0072 15.9 2.9 0.13 11.9 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III IBR PF01485.16 OAP63249.1 - 3e-08 33.4 8.0 3e-08 33.4 5.5 3.6 3 1 0 3 3 3 2 IBR domain HSP20 PF00011.16 OAP63250.1 - 7.7e-09 35.3 0.0 3.2e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.16 OAP63251.1 - 2.1e-08 33.9 0.0 3.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family RhoGAP PF00620.22 OAP63252.1 - 1.4e-37 128.6 0.1 3.1e-37 127.5 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 OAP63252.1 - 6.4e-33 112.6 32.7 5.9e-13 48.6 3.9 4.9 5 0 0 5 5 5 4 LIM domain DZR PF12773.2 OAP63252.1 - 0.39 10.5 19.3 0.53 10.1 0.9 4.2 3 1 0 3 3 3 0 Double zinc ribbon Beta_elim_lyase PF01212.16 OAP63253.1 - 2.9e-70 236.7 0.0 3.6e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAP63253.1 - 1.4e-05 24.2 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAP63253.1 - 0.00039 18.8 0.0 0.00064 18.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 OAP63253.1 - 0.058 12.4 0.1 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Yippee-Mis18 PF03226.9 OAP63254.1 - 0.00011 22.2 1.8 0.001 19.0 1.5 2.3 1 1 1 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FlaC_arch PF05377.6 OAP63254.1 - 0.14 12.0 0.7 0.43 10.4 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pkinase PF00069.20 OAP63255.1 - 8.1e-68 228.3 0.0 1.1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63255.1 - 4.2e-33 114.5 0.0 7.1e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 OAP63255.1 - 5.7e-10 39.1 0.1 1.7e-09 37.6 0.1 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 OAP63255.1 - 0.0031 16.5 0.0 0.02 13.8 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 OAP63255.1 - 0.018 13.8 0.1 0.028 13.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 OAP63255.1 - 0.035 13.8 0.1 0.31 10.7 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 OAP63255.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_34 PF05637.7 OAP63256.1 - 3.5e-45 154.3 0.0 1e-41 143.0 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Peptidase_S9 PF00326.16 OAP63257.1 - 0.00012 21.4 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP63257.1 - 0.022 14.5 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 OAP63257.1 - 0.081 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein FAM176 PF14851.1 OAP63258.1 - 2.2 7.9 5.1 3.1 7.4 3.6 1.2 1 0 0 1 1 1 0 FAM176 family Tom22 PF04281.8 OAP63258.1 - 2.6 7.5 6.6 3.9 7.0 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NARP1 PF12569.3 OAP63258.1 - 3.3 6.3 7.0 4.1 6.0 4.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.5 OAP63258.1 - 3.5 7.4 6.5 5.3 6.8 4.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1777 PF08648.7 OAP63258.1 - 5.4 6.7 20.8 7.7 6.2 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) p450 PF00067.17 OAP63259.1 - 2.6e-50 171.3 0.0 3.5e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WSC PF01822.14 OAP63261.1 - 9.1e-99 323.5 121.8 2e-19 69.3 5.5 7.1 7 0 0 7 7 7 6 WSC domain PQQ_3 PF13570.1 OAP63261.1 - 0.09 13.0 10.2 1.1 9.6 0.1 4.8 4 0 0 4 4 4 0 PQQ-like domain DUF386 PF04074.7 OAP63261.1 - 0.33 10.4 0.0 0.62 9.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF386) GFA PF04828.9 OAP63263.1 - 3.7e-13 49.2 0.1 7.6e-13 48.2 0.1 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sugar_tr PF00083.19 OAP63264.1 - 1.7e-73 247.7 24.7 2e-73 247.5 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63264.1 - 2.3e-21 75.9 28.8 2.3e-21 75.9 20.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP63265.1 - 5.3e-29 100.8 0.0 9.4e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 OAP63265.1 - 0.0016 17.1 2.4 0.042 12.4 0.0 2.7 3 0 0 3 3 3 2 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP63266.1 - 2.3e-52 177.8 32.6 2.3e-52 177.8 22.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP63266.1 - 2.8e-11 42.6 26.0 1.5e-10 40.2 17.8 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 OAP63266.1 - 1e-06 27.2 3.4 1e-06 27.2 2.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 OAP63266.1 - 0.00025 19.2 1.8 0.00025 19.2 1.3 1.9 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Milton PF12448.3 OAP63267.1 - 0.18 11.9 4.9 0.23 11.6 3.4 1.2 1 0 0 1 1 1 0 Kinesin associated protein Septin PF00735.13 OAP63268.1 - 4.4e-12 45.6 0.0 7e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Septin Miro PF08477.8 OAP63268.1 - 0.0036 17.8 0.0 0.0073 16.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAP63268.1 - 0.005 16.7 0.0 0.013 15.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 OAP63268.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 NTPase Arch_ATPase PF01637.13 OAP63268.1 - 0.0075 15.9 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 OAP63268.1 - 0.022 14.7 0.1 0.088 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 OAP63268.1 - 0.028 14.6 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 OAP63268.1 - 0.049 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 OAP63268.1 - 0.053 12.7 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 OAP63268.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTF2 PF02136.15 OAP63269.1 - 6e-24 84.6 0.1 9.6e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 OAP63269.1 - 1.9e-07 30.6 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP63269.1 - 3.8e-07 30.0 0.0 6.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP63269.1 - 0.00015 21.5 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAP63269.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Moulting_cycle PF04870.11 OAP63270.1 - 0.0015 17.7 1.2 0.0017 17.5 0.9 1.2 1 0 0 1 1 1 1 Moulting cycle Ubiquitin_3 PF14836.1 OAP63270.1 - 0.12 12.0 2.5 0.17 11.5 1.5 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain Muted PF14942.1 OAP63270.1 - 0.2 11.5 7.1 0.26 11.1 4.9 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF572 PF04502.8 OAP63270.1 - 0.43 9.7 5.4 0.5 9.5 3.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3775 PF12616.3 OAP63270.1 - 0.5 10.2 2.6 0.82 9.4 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3775) DUF1654 PF07867.6 OAP63270.1 - 0.71 9.2 4.7 0.72 9.2 1.5 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1654) DUF217 PF02697.9 OAP63270.1 - 4.2 7.6 7.1 0.21 11.8 1.2 1.6 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Peptidase_C50 PF03568.12 OAP63271.1 - 9.7e-95 317.4 0.0 3.1e-94 315.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.1 OAP63271.1 - 2e-05 24.4 0.1 2e-05 24.4 0.1 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAP63271.1 - 0.0012 18.4 0.5 0.094 12.3 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP63271.1 - 0.0016 18.7 5.1 0.24 11.7 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAP63271.1 - 0.0048 16.5 1.1 3.1 7.4 0.0 3.6 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 OAP63271.1 - 0.016 14.9 0.9 17 5.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP63271.1 - 0.038 13.8 11.0 0.77 9.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP63271.1 - 0.075 12.8 1.8 9.1 6.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAP63271.1 - 0.43 10.5 7.2 0.45 10.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 OAP63273.1 - 5.4e-17 61.9 0.0 7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP63273.1 - 1.3e-14 54.4 0.0 2.4e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP63273.1 - 4.3e-14 52.3 0.0 4.4e-13 49.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP63273.1 - 1.8e-13 50.7 0.0 4.4e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP63273.1 - 3.5e-12 46.8 0.0 6.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP63273.1 - 1.7e-07 31.5 0.0 3.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 OAP63273.1 - 5.1e-05 22.4 0.0 6.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 OAP63273.1 - 0.0002 20.8 0.0 0.0017 17.7 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 OAP63273.1 - 0.00028 20.0 0.0 0.001 18.2 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAP63273.1 - 0.00088 18.6 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAP63273.1 - 0.0064 16.5 0.1 0.026 14.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 OAP63273.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TPP_enzyme_M PF00205.17 OAP63274.1 - 1.1e-34 119.1 0.1 3.4e-34 117.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 OAP63274.1 - 1.6e-32 112.3 0.3 4.7e-32 110.8 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAP63274.1 - 4.9e-19 68.3 0.4 5.6e-18 64.9 0.3 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Chal_sti_synt_N PF00195.14 OAP63276.1 - 6e-26 91.0 0.0 8.8e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 OAP63276.1 - 8.9e-17 61.4 0.0 2.5e-16 59.9 0.0 1.8 2 1 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.5 OAP63276.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 OAP63276.1 - 0.00084 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.7 OAP63276.1 - 0.0037 16.3 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein p450 PF00067.17 OAP63277.1 - 2.7e-51 174.5 0.0 2.1e-50 171.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 YlqD PF11068.3 OAP63277.1 - 0.026 14.5 0.7 0.048 13.7 0.5 1.3 1 0 0 1 1 1 0 YlqD protein Ank_2 PF12796.2 OAP63278.1 - 5.2e-41 138.8 0.0 4.4e-18 65.4 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 OAP63278.1 - 2.6e-37 124.7 3.2 1.1e-10 40.7 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 OAP63278.1 - 4.7e-37 127.0 8.1 4.7e-37 127.0 5.6 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 OAP63278.1 - 5.7e-27 93.6 7.0 2.9e-08 33.9 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP63278.1 - 4e-26 90.4 4.7 9.1e-10 38.4 0.1 5.6 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP63278.1 - 5.2e-24 81.9 3.1 1.4e-07 31.0 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat ATP-synt_ab PF00006.20 OAP63279.1 - 2.1e-70 236.5 0.0 3e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAP63279.1 - 2.8e-27 95.4 0.7 2e-26 92.6 0.5 2.4 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAP63279.1 - 2.2e-15 56.6 4.2 3.1e-15 56.1 1.5 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 OAP63279.1 - 0.014 15.2 0.5 0.06 13.2 0.4 2.1 1 1 0 1 1 1 0 HAS barrel domain AAA_25 PF13481.1 OAP63279.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ADH_N PF08240.7 OAP63280.1 - 1.2e-07 31.4 0.1 3.9e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP63280.1 - 0.017 14.6 0.1 0.05 13.1 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Sulfatase_C PF14707.1 OAP63281.1 - 3.9 7.7 6.1 6.3 7.1 0.1 2.5 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase tRNA-synt_His PF13393.1 OAP63282.1 - 2.2e-41 141.9 0.0 3.4e-35 121.6 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 OAP63282.1 - 1e-15 57.7 0.0 2.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAP63282.1 - 7.6e-11 41.8 0.0 1.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 OAP63282.1 - 0.0091 14.7 0.0 0.67 8.6 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 OAP63282.1 - 0.051 12.7 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) RNase_P_p30 PF01876.11 OAP63284.1 - 2.7e-49 166.2 0.0 4.1e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.20 OAP63285.1 - 5.8e-58 196.0 0.0 6.9e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63285.1 - 1.8e-18 66.5 0.0 2.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP63285.1 - 1e-06 28.6 0.2 0.00016 21.4 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 OAP63285.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 OAP63285.1 - 0.024 14.2 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 OAP63285.1 - 0.059 12.4 0.2 0.1 11.6 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_2 PF00891.13 OAP63286.1 - 1.1e-29 103.4 0.0 1.6e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 OAP63286.1 - 0.00064 19.4 0.2 0.0017 18.1 0.1 1.8 1 0 0 1 1 1 1 Dimerisation domain tRNA-synt_1 PF00133.17 OAP63288.1 - 1.5e-208 693.6 1.0 8.2e-208 691.2 0.7 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAP63288.1 - 1.1e-33 116.1 5.0 1.7e-33 115.5 0.1 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAP63288.1 - 8.5e-15 54.3 1.9 9.8e-05 21.1 0.1 4.8 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 OAP63288.1 - 1.4e-07 31.0 9.7 3.6e-07 29.6 0.1 4.0 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 OAP63288.1 - 0.0028 16.8 0.0 0.025 13.7 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain IncA PF04156.9 OAP63288.1 - 3.8 7.0 5.6 8.7 5.8 3.9 1.5 1 0 0 1 1 1 0 IncA protein Cation_efflux PF01545.16 OAP63289.1 - 6.8e-57 192.7 0.1 9.7e-57 192.2 0.1 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 OAP63289.1 - 0.02 13.8 7.5 0.22 10.4 0.9 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter SelP_N PF04592.9 OAP63289.1 - 1.1 8.6 14.8 0.023 14.0 1.6 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region FGGY_C PF02782.11 OAP63290.1 - 9e-31 107.0 0.0 1.5e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 OAP63290.1 - 5.2e-20 71.7 0.0 1.4e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain DUF846 PF05832.7 OAP63291.1 - 4.8e-47 159.2 9.5 5.7e-47 158.9 6.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) MpPF26 PF07666.6 OAP63291.1 - 0.054 13.3 7.0 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 TMEM220 PF15071.1 OAP63291.1 - 0.36 11.2 3.9 0.13 12.7 0.6 1.7 2 0 0 2 2 2 0 Transmembrane family 220, helix Tic20 PF09685.5 OAP63291.1 - 6.7 6.7 12.5 1.7 8.6 1.0 2.2 2 0 0 2 2 2 0 Tic20-like protein LRR_4 PF12799.2 OAP63293.1 - 2.3e-17 62.1 17.7 4.7e-10 38.8 0.3 3.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.18 OAP63293.1 - 8.8e-16 58.5 0.2 1.6e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.1 OAP63293.1 - 3.9e-08 32.9 3.5 1e-07 31.5 2.4 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 OAP63293.1 - 1e-06 27.9 7.4 0.012 15.5 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 OAP63293.1 - 5.4e-05 22.7 9.5 0.15 12.3 0.1 4.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 OAP63293.1 - 0.072 13.1 0.1 0.072 13.1 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat Complex1_LYR_2 PF13233.1 OAP63294.1 - 2.7e-08 34.2 0.4 3e-08 34.0 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAP63294.1 - 9.6e-08 31.7 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAP63294.1 - 6.5e-06 26.2 0.0 8.9e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Peptidase_S15 PF02129.13 OAP63295.1 - 5.1e-36 124.4 0.0 1.4e-33 116.4 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 OAP63295.1 - 7.2e-25 88.1 0.0 9.6e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 OAP63295.1 - 1.2e-06 28.5 0.1 3.1e-06 27.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 OAP63296.1 - 3.7e-37 127.8 28.3 3.7e-37 127.8 19.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 OAP63297.1 - 2.5e-18 65.9 37.7 1.4e-16 60.1 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 OAP63297.1 - 0.0006 18.4 14.6 0.0052 15.3 9.8 2.1 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like ECH PF00378.15 OAP63298.1 - 2e-37 128.6 0.0 2.4e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Abhydrolase_3 PF07859.8 OAP63299.1 - 4.6e-35 121.1 0.0 3.1e-34 118.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 OAP63300.1 - 2.5e-09 36.2 0.3 2.5e-09 36.2 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63300.1 - 3.4e-08 33.2 5.0 5.4e-08 32.6 3.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 OAP63301.1 - 4.8e-37 127.6 7.5 7.5e-37 126.9 5.2 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1700 PF08006.6 OAP63301.1 - 0.035 13.4 1.1 0.3 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Cyclin_N PF00134.18 OAP63303.1 - 3.5e-16 58.9 0.4 6e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAP63303.1 - 4.6e-08 33.0 0.0 3.2e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 OAP63303.1 - 0.027 14.2 0.3 0.061 13.1 0.1 1.7 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Fungal_trans_2 PF11951.3 OAP63304.1 - 0.0012 17.5 1.1 0.56 8.7 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP63305.1 - 3.1e-31 108.3 32.6 3.1e-31 108.3 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OPT PF03169.10 OAP63306.1 - 4.7e-160 534.0 24.2 5.3e-160 533.8 16.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein A1_Propeptide PF07966.7 OAP63306.1 - 0.0025 17.5 1.1 0.28 11.0 0.0 2.4 2 0 0 2 2 2 2 A1 Propeptide HATPase_c PF02518.21 OAP63307.1 - 7.1e-21 74.0 0.1 1.8e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP63307.1 - 6.4e-19 68.0 0.0 1.4e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 OAP63307.1 - 1.2e-12 47.6 0.0 5.5e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain NKAIN PF05640.9 OAP63307.1 - 0.046 12.6 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein HATPase_c_5 PF14501.1 OAP63307.1 - 0.1 12.2 0.0 0.89 9.2 0.0 2.3 2 0 0 2 2 2 0 GHKL domain MFS_1 PF07690.11 OAP63309.1 - 1.7e-36 125.6 56.7 1.8e-36 125.6 37.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 OAP63310.1 - 3.3e-32 111.6 0.1 4.4e-32 111.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP63310.1 - 1.5e-24 87.1 0.0 8.4e-24 84.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP63310.1 - 4e-15 55.9 0.0 5.6e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAP63310.1 - 0.0026 17.4 0.2 0.0041 16.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 OAP63310.1 - 0.0081 16.0 0.5 0.016 15.0 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain YrhK PF14145.1 OAP63311.1 - 1.7e-05 24.3 19.4 0.0012 18.5 0.2 4.3 4 1 0 4 4 4 3 YrhK-like protein Clr5 PF14420.1 OAP63312.1 - 9.5e-06 25.4 0.4 2.7e-05 23.9 0.2 1.9 2 0 0 2 2 2 1 Clr5 domain adh_short_C2 PF13561.1 OAP63313.1 - 1.4e-35 123.1 0.9 1.6e-35 123.0 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP63313.1 - 4.7e-32 111.1 3.0 6.1e-32 110.8 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP63313.1 - 1.3e-13 51.0 0.9 1.8e-13 50.5 0.6 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAP63313.1 - 0.0051 16.4 0.2 0.0087 15.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 OAP63313.1 - 0.011 15.5 1.2 0.019 14.8 0.8 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IMPDH PF00478.20 OAP63313.1 - 0.28 10.0 4.9 0.062 12.1 0.8 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain CoA_binding_2 PF13380.1 OAP63313.1 - 0.37 10.9 2.2 17 5.5 0.2 2.9 1 1 1 2 2 2 0 CoA binding domain Fungal_trans_2 PF11951.3 OAP63314.1 - 2.4e-07 29.7 0.0 3.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF336 PF03928.9 OAP63316.1 - 9.4e-27 93.4 0.0 1.1e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) SLAC1 PF03595.12 OAP63317.1 - 4.5e-82 275.3 35.7 5.1e-82 275.1 24.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2945 PF11160.3 OAP63318.1 - 0.017 14.9 1.9 0.017 14.9 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2945) AT_hook PF02178.14 OAP63318.1 - 0.99 9.2 5.4 0.59 9.9 0.8 3.1 2 0 0 2 2 2 0 AT hook motif CHZ PF09649.5 OAP63319.1 - 0.0036 16.5 1.2 0.0078 15.4 0.8 1.6 1 0 0 1 1 1 1 Histone chaperone domain CHZ CPDase PF07823.6 OAP63320.1 - 1.7e-30 106.0 0.0 1.9e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 OAP63320.1 - 0.00012 21.8 0.1 0.13 11.9 0.0 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily p450 PF00067.17 OAP63321.1 - 7.8e-67 225.7 0.0 9.3e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 OAP63322.1 - 2.2e-22 80.1 0.0 4.6e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP63322.1 - 8.8e-08 32.0 0.4 4e-07 29.9 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP63322.1 - 6.9e-05 22.6 0.0 0.0028 17.4 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP63322.1 - 0.00026 20.9 0.0 0.024 14.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP63322.1 - 0.00028 20.0 0.8 0.00065 18.8 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 OAP63322.1 - 0.00081 19.4 0.1 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 OAP63322.1 - 0.0012 17.1 0.0 0.032 12.4 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP63322.1 - 0.0014 17.6 0.0 0.0041 16.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 OAP63322.1 - 0.011 14.6 1.1 0.023 13.5 0.8 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 OAP63322.1 - 0.036 14.4 0.6 9.5 6.7 0.5 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 OAP63322.1 - 0.038 13.1 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 OAP63322.1 - 0.14 12.0 2.1 0.33 10.7 0.6 2.1 2 0 0 2 2 2 0 ThiF family DUF3425 PF11905.3 OAP63323.1 - 2.7e-16 59.6 0.0 7.5e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP63323.1 - 5.8e-08 32.5 3.1 1.1e-07 31.7 2.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor Med9 PF07544.8 OAP63323.1 - 0.016 14.9 0.9 0.045 13.4 0.4 1.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_2 PF07716.10 OAP63323.1 - 0.025 14.4 11.2 0.03 14.1 5.1 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Striatin PF08232.7 OAP63323.1 - 0.11 12.7 2.1 0.19 12.0 1.5 1.4 1 0 0 1 1 1 0 Striatin family PEP-utilisers_N PF05524.8 OAP63323.1 - 0.12 12.1 2.6 0.27 11.0 1.8 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal bZIP_Maf PF03131.12 OAP63323.1 - 0.27 11.5 7.4 0.54 10.5 5.1 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor ERCC4 PF02732.10 OAP63325.1 - 1.1e-31 109.5 0.0 1.7e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 OAP63325.1 - 0.00057 20.0 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain MutL PF13941.1 OAP63325.1 - 0.15 10.3 0.0 0.23 9.7 0.0 1.2 1 0 0 1 1 1 0 MutL protein MARVEL PF01284.18 OAP63326.1 - 0.0026 17.5 5.4 0.0042 16.8 3.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain UPF0542 PF15086.1 OAP63326.1 - 0.022 14.4 0.4 0.061 13.0 0.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 ATP-synt_B PF00430.13 OAP63326.1 - 0.095 12.5 0.2 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) VKOR PF07884.9 OAP63326.1 - 0.65 9.8 5.2 0.34 10.7 0.8 2.3 2 1 1 3 3 3 0 Vitamin K epoxide reductase family Pyr_redox_2 PF07992.9 OAP63328.1 - 9.9e-25 87.5 0.0 1.8e-15 57.3 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP63328.1 - 1.8e-09 37.9 0.0 3.5e-07 30.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP63328.1 - 0.00053 20.1 0.0 0.057 13.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP63328.1 - 0.018 15.0 0.0 3.5 7.7 0.0 3.4 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP63328.1 - 0.071 12.8 0.2 6.6 6.4 0.1 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 OAP63328.1 - 0.075 12.0 0.4 2.1 7.3 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain CUE PF02845.11 OAP63329.1 - 3.3e-05 23.2 0.0 5.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 OAP63329.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF1296 PF06972.6 OAP63329.1 - 0.2 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) TPR_16 PF13432.1 OAP63330.1 - 9.1 7.0 7.3 40 5.0 0.3 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat GST_N PF02798.15 OAP63331.1 - 6.7e-15 55.0 0.0 1.8e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP63331.1 - 6.5e-13 48.4 0.0 1.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP63331.1 - 7.3e-13 48.5 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP63331.1 - 6.9e-10 38.7 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP63331.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP63331.1 - 0.00097 19.5 0.1 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Oxysterol_BP PF01237.13 OAP63332.1 - 2.7e-84 282.6 0.9 3.4e-84 282.3 0.6 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein F_bP_aldolase PF01116.15 OAP63333.1 - 6e-98 327.4 0.0 6.8e-98 327.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DAG_kinase_N PF14513.1 OAP63333.1 - 0.048 13.8 0.1 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF2973 PF11189.3 OAP63333.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Arginosuc_synth PF00764.14 OAP63334.1 - 5.8e-146 486.4 0.0 6.6e-146 486.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 OAP63334.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.8 OAP63334.1 - 0.026 13.7 0.1 0.072 12.3 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC UCH PF00443.24 OAP63335.1 - 8.2e-40 136.6 0.0 2.6e-33 115.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAP63335.1 - 1.3e-12 47.7 0.2 7e-09 35.5 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HET PF06985.6 OAP63336.1 - 6e-23 81.5 0.3 1.3e-22 80.4 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GrpB PF04229.9 OAP63337.1 - 9.2e-27 93.7 0.0 2.3e-22 79.4 0.0 2.0 1 1 1 2 2 2 2 GrpB protein DUF221 PF02714.10 OAP63338.1 - 3e-88 295.8 21.9 3e-88 295.8 15.2 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAP63338.1 - 3.9e-39 133.7 0.5 1.2e-38 132.1 0.4 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAP63338.1 - 1.1e-15 57.9 0.0 2.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) TMF_TATA_bd PF12325.3 OAP63338.1 - 0.26 11.0 0.1 2.3 7.9 0.0 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TMEM237 PF15383.1 OAP63339.1 - 1.8 7.6 3.8 3 6.9 2.6 1.5 1 1 0 1 1 1 0 Transmembrane protein 237 Fungal_trans PF04082.13 OAP63340.1 - 1.7e-17 63.1 2.8 2.8e-17 62.4 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TarH PF02203.10 OAP63340.1 - 0.026 14.3 0.2 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Peptidase_M19 PF01244.16 OAP63341.1 - 1.2e-100 336.6 0.0 1.4e-100 336.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Imm42 PF15601.1 OAP63341.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 42 Beta-lactamase PF00144.19 OAP63342.1 - 3.1e-30 105.3 0.0 5e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.11 OAP63343.1 - 1.9e-27 95.9 35.5 2.8e-27 95.3 24.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 OAP63343.1 - 0.006 16.5 3.5 0.019 15.0 0.5 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Ank_4 PF13637.1 OAP63344.1 - 0.001 19.5 0.0 0.094 13.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAP63344.1 - 0.018 15.3 0.0 0.23 11.8 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP63344.1 - 0.032 14.4 0.2 1.6 9.1 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP63344.1 - 0.046 13.9 0.0 6.2 7.3 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Kinesin-relat_1 PF12711.2 OAP63345.1 - 0.0025 18.1 1.9 0.0025 18.1 1.3 1.6 1 1 0 1 1 1 1 Kinesin motor PRP3 PF08572.5 OAP63345.1 - 0.19 11.0 2.9 0.17 11.2 1.2 1.4 1 1 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Cep57_MT_bd PF06657.8 OAP63345.1 - 0.76 9.7 5.6 1.6 8.7 3.9 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 NUDIX PF00293.23 OAP63347.1 - 2.7e-15 56.1 0.1 6.7e-15 54.9 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain WD-3 PF09765.4 OAP63347.1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 1 WD-repeat region Cyt-b5 PF00173.23 OAP63347.1 - 0.044 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Sugar_tr PF00083.19 OAP63348.1 - 1.4e-93 313.9 31.6 1.6e-93 313.7 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63348.1 - 4.2e-23 81.6 43.0 5.1e-16 58.3 12.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily BTB PF00651.26 OAP63349.1 - 0.0021 18.0 0.1 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Romo1 PF10247.4 OAP63350.1 - 0.0045 17.1 0.1 2.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 DUF456 PF04306.8 OAP63350.1 - 0.039 13.9 0.1 8.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Fungal_trans PF04082.13 OAP63351.1 - 2e-20 72.7 0.1 3e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4078 PF13300.1 OAP63352.1 - 9.7e-30 102.5 13.7 9.7e-30 102.5 9.5 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Dec-1 PF04624.9 OAP63352.1 - 0.024 14.2 0.0 0.099 12.2 0.0 2.1 1 0 0 1 1 1 0 Dec-1 repeat Bunya_RdRp PF04196.7 OAP63352.1 - 2.1 6.2 5.4 0.12 10.3 0.4 1.4 2 0 0 2 2 2 0 Bunyavirus RNA dependent RNA polymerase AAA PF00004.24 OAP63353.1 - 5.7e-15 55.6 0.0 8.5e-14 51.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 OAP63353.1 - 7e-11 42.0 0.2 3.2e-10 39.9 0.1 2.0 1 1 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.1 OAP63353.1 - 9.5e-06 25.7 0.9 2.3e-05 24.4 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 OAP63353.1 - 0.00022 22.0 0.1 0.00096 19.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAP63353.1 - 0.00034 20.3 0.0 0.00086 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAP63353.1 - 0.00049 19.5 0.0 0.00099 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAP63353.1 - 0.0064 16.3 0.1 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP63353.1 - 0.0079 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 OAP63353.1 - 0.0082 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP63353.1 - 0.0086 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 OAP63353.1 - 0.018 14.5 0.0 0.056 12.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 OAP63353.1 - 0.029 14.5 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 OAP63353.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 OAP63353.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 OAP63353.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 OAP63353.1 - 0.085 12.0 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 OAP63353.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Retinal PF15449.1 OAP63354.1 - 0.0071 14.0 3.6 0.0096 13.6 2.5 1.1 1 0 0 1 1 1 1 Retinal protein C1_3 PF07649.7 OAP63354.1 - 0.019 14.9 4.8 0.019 14.9 3.4 5.4 5 0 0 5 5 5 0 C1-like domain BAF1_ABF1 PF04684.8 OAP63354.1 - 0.092 11.5 3.9 0.18 10.6 2.7 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-LITAF-like PF10601.4 OAP63355.1 - 1.6e-22 79.0 6.0 2.1e-22 78.7 4.2 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 OAP63355.1 - 0.12 12.3 0.3 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-ISL3 PF14690.1 OAP63355.1 - 1 9.4 5.0 5.5 7.1 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PepSY_TM_3 PF13706.1 OAP63355.1 - 1.1 8.6 6.5 1.5 8.2 1.9 2.1 2 0 0 2 2 2 0 PepSY-associated TM helix Asp PF00026.18 OAP63356.1 - 7.6e-53 179.8 0.0 8.9e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAP63356.1 - 1.6e-07 31.4 0.1 7.3e-07 29.2 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAP63356.1 - 8.3e-06 25.4 0.0 0.0078 15.7 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 OAP63356.1 - 0.00032 20.4 0.1 0.0087 15.8 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAP63356.1 - 0.03 14.8 0.3 2.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Aspartyl protease MtN3_slv PF03083.11 OAP63356.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange CFEM PF05730.6 OAP63357.1 - 3.9e-05 23.3 6.4 3.9e-05 23.3 4.4 2.7 3 0 0 3 3 3 1 CFEM domain HATPase_c PF02518.21 OAP63358.1 - 8.9e-30 102.6 0.0 2e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP63358.1 - 6.3e-23 80.9 0.6 5e-22 78.0 0.1 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 OAP63358.1 - 2e-20 72.5 0.0 7.4e-20 70.7 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 OAP63358.1 - 6.9e-14 52.2 0.0 3.6e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.1 OAP63358.1 - 2.6e-13 50.7 0.2 3.6e-12 47.0 0.0 2.6 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 OAP63358.1 - 2.7e-10 40.4 0.0 6.2e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 OAP63358.1 - 1.1e-06 28.8 0.1 3.7e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 OAP63358.1 - 2.1e-06 27.1 0.0 3.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HATPase_c_3 PF13589.1 OAP63358.1 - 0.00042 19.9 0.0 0.0053 16.4 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.12 OAP63358.1 - 0.0017 17.4 0.0 0.0047 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Arch_ATPase PF01637.13 OAP63358.1 - 0.012 15.3 0.0 0.068 12.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase TPR_12 PF13424.1 OAP63358.1 - 0.014 15.3 1.3 0.06 13.2 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_29 PF13555.1 OAP63358.1 - 0.034 13.6 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 OAP63358.1 - 0.09 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DEC-1_N PF04625.8 OAP63359.1 - 0.21 10.2 9.3 0.02 13.6 2.7 1.8 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Baculo_PEP_C PF04513.7 OAP63360.1 - 0.0069 16.2 23.9 0.039 13.7 16.5 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4160 PF13711.1 OAP63361.1 - 0.12 12.2 0.5 0.58 10.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) TMA7 PF09072.5 OAP63362.1 - 1.6e-26 92.5 20.5 1.7e-26 92.4 14.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF4646 PF15496.1 OAP63363.1 - 0.0064 16.5 0.5 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) TilS PF09179.6 OAP63363.1 - 0.016 15.1 0.1 0.065 13.2 0.0 2.0 1 0 0 1 1 1 0 TilS substrate binding domain DUF3669 PF12417.3 OAP63365.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein Pkinase PF00069.20 OAP63366.1 - 4.8e-51 173.4 0.0 1.2e-50 172.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63366.1 - 3.3e-24 85.3 0.0 4.1e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 OAP63366.1 - 0.0044 15.8 0.0 0.0066 15.3 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 OAP63366.1 - 0.03 13.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family FAD_binding_2 PF00890.19 OAP63367.1 - 9.8e-37 126.7 0.0 1.4e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP63367.1 - 1.5e-05 24.0 0.2 4.3e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP63367.1 - 0.00029 20.7 0.2 0.0088 15.9 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP63367.1 - 0.0038 17.5 0.1 1.9 8.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP63367.1 - 0.025 14.3 0.4 0.7 9.6 0.0 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding GFA PF04828.9 OAP63368.1 - 6e-09 35.7 0.1 8.8e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_2_N PF02837.13 OAP63369.1 - 1.5e-07 31.1 0.0 3.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 OAP63369.1 - 2.1e-07 31.3 0.0 1.4e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 OAP63369.1 - 2.4e-05 23.4 0.1 0.00011 21.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Abhydrolase_6 PF12697.2 OAP63370.1 - 5.8e-21 75.4 0.0 6.9e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP63370.1 - 8.9e-09 35.2 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP63370.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 OAP63370.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF3425 PF11905.3 OAP63371.1 - 5.2e-17 62.0 7.5 1.6e-15 57.2 5.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) TPT PF03151.11 OAP63374.1 - 1.5e-25 89.6 12.0 1.5e-25 89.6 8.3 2.3 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 OAP63374.1 - 0.016 14.0 17.3 0.25 10.2 11.8 2.3 1 1 0 1 1 1 0 UAA transporter family NAD_binding_8 PF13450.1 OAP63375.1 - 4.5e-09 36.1 0.0 1.5e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAP63375.1 - 2.9e-06 26.6 0.0 3.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 OAP63375.1 - 4.3e-05 23.6 0.3 0.00016 21.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP63375.1 - 0.0023 17.8 0.0 0.0095 15.8 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP63375.1 - 0.0046 16.0 0.0 0.0087 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAP63375.1 - 0.041 12.9 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 OAP63375.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 OAP63375.1 - 0.088 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 OAP63375.1 - 0.097 12.4 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3210 PF11489.3 OAP63376.1 - 9.6e-167 556.7 68.4 9.6e-167 556.7 47.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3210) Surp PF01805.15 OAP63377.1 - 4.3e-19 67.9 0.0 7.6e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Surp module Tannase PF07519.6 OAP63378.1 - 1e-14 54.1 0.0 1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.11 OAP63379.1 - 8.2e-18 64.2 5.6 1.1e-17 63.8 3.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RuBisCO_large_N PF02788.11 OAP63379.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain CoA_transf_3 PF02515.12 OAP63381.1 - 1.3e-31 109.3 0.0 1.7e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III GXWXG PF14231.1 OAP63381.1 - 0.078 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 GXWXG protein Methyltransf_PK PF05891.7 OAP63382.1 - 1.1e-54 185.1 0.0 2.4e-41 141.4 0.0 2.9 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 OAP63382.1 - 3.1e-05 23.7 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP63382.1 - 0.0025 18.3 0.0 0.0056 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RTA1 PF04479.8 OAP63383.1 - 2.6e-44 151.4 7.4 3.7e-44 150.8 5.1 1.2 1 0 0 1 1 1 1 RTA1 like protein NDUF_B12 PF08122.7 OAP63383.1 - 0.74 9.5 2.8 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family adh_short PF00106.20 OAP63385.1 - 2.4e-16 60.0 0.1 3.8e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP63385.1 - 3.6e-09 36.7 0.0 4.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP63385.1 - 1.4e-05 24.8 0.1 1.9e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Hexokinase_1 PF00349.16 OAP63385.1 - 0.035 13.4 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Hexokinase Lyase_1 PF00206.15 OAP63386.1 - 1.5e-47 162.3 0.0 2.9e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 OAP63386.1 - 6.7e-23 80.4 0.1 1e-20 73.5 0.0 2.5 2 0 0 2 2 2 2 Adenylosuccinate lyase C-terminus YkyA PF10368.4 OAP63386.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein TFIIB PF00382.14 OAP63387.1 - 5.7e-27 93.3 1.5 6.1e-17 61.1 0.0 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 OAP63387.1 - 1.4e-14 54.0 9.3 1.4e-14 54.0 6.4 4.7 4 2 0 4 4 4 1 Brf1-like TBP-binding domain EBV-NA3 PF05009.7 OAP63390.1 - 0.16 11.1 0.7 0.32 10.2 0.5 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Otopetrin PF03189.8 OAP63391.1 - 0.049 12.6 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Cas_CT1975 PF09344.5 OAP63391.1 - 0.36 10.1 5.6 0.25 10.6 0.3 2.2 2 0 0 2 2 2 0 CT1975-like protein YWFCY PF14293.1 OAP63391.1 - 0.92 9.3 3.4 16 5.4 2.4 2.3 1 1 0 1 1 1 0 YWFCY protein Myb_DNA-bind_6 PF13921.1 OAP63392.1 - 0.0093 16.0 0.3 0.13 12.3 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Talin_middle PF09141.5 OAP63392.1 - 0.022 14.4 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Talin, middle domain BTB PF00651.26 OAP63393.1 - 4.9e-09 36.1 0.0 8.6e-08 32.1 0.0 2.7 2 1 1 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.10 OAP63393.1 - 0.13 12.3 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain ADH_N PF08240.7 OAP63395.1 - 7.9e-27 93.1 1.9 1.8e-26 92.0 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP63395.1 - 3.8e-21 74.9 0.5 4e-15 55.5 0.5 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP63395.1 - 0.001 19.9 0.0 0.0028 18.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF4453 PF14627.1 OAP63395.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Amidinotransf PF02274.12 OAP63395.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Amidinotransferase CFEM PF05730.6 OAP63398.1 - 1.9e-10 40.3 7.6 1.9e-10 40.3 5.3 1.8 2 0 0 2 2 2 1 CFEM domain Cu-oxidase_2 PF07731.9 OAP63400.1 - 1.1e-39 135.1 3.9 5.3e-35 119.9 0.7 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 OAP63400.1 - 2.3e-37 127.3 8.9 3.1e-36 123.6 0.1 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 OAP63400.1 - 1.8e-35 122.1 0.1 2.4e-30 105.5 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Shisa PF13908.1 OAP63400.1 - 0.021 15.0 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Cupredoxin_1 PF13473.1 OAP63400.1 - 0.18 11.7 0.0 23 4.9 0.0 2.8 2 1 0 2 2 2 0 Cupredoxin-like domain Fungal_trans PF04082.13 OAP63401.1 - 6e-06 25.3 0.0 1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 OAP63402.1 - 2.7e-12 46.1 0.1 9.9e-12 44.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ferric_reduct PF01794.14 OAP63403.1 - 3.6e-11 43.2 11.0 3.6e-11 43.2 7.6 2.2 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 OAP63403.1 - 3.3e-09 36.5 0.1 8.4e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 FAD-binding domain Fungal_trans PF04082.13 OAP63404.1 - 1.5e-23 83.0 0.2 3.5e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63404.1 - 7.2e-07 29.0 13.1 1.1e-06 28.3 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCMA-Tall_bind PF09257.5 OAP63404.1 - 0.01 15.7 5.4 0.023 14.6 3.7 1.6 1 0 0 1 1 1 0 BCMA, TALL-1 binding Glyco_hydro_2 PF00703.16 OAP63405.1 - 7.9e-11 42.3 0.0 2.7e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 OAP63405.1 - 2.7e-09 36.7 0.0 1.1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 OAP63405.1 - 0.0036 16.2 0.1 0.0071 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF427 PF04248.7 OAP63406.1 - 2.4e-28 97.6 0.1 3.1e-28 97.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Sulf_transp PF04143.9 OAP63407.1 - 3.4e-14 52.5 41.9 8.6e-10 38.4 9.9 4.3 4 1 1 5 5 5 2 Sulphur transport DUF4341 PF14241.1 OAP63407.1 - 5.5e-05 22.7 1.1 5.5e-05 22.7 0.7 5.0 5 1 0 5 5 5 1 Domain of unknown function (DUF4341) FCH PF00611.18 OAP63409.1 - 3e-19 68.9 0.0 6.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 OAP63409.1 - 5.5e-12 44.8 0.0 1.6e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAP63409.1 - 1.6e-10 40.3 0.0 1.7e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 OAP63409.1 - 1.9e-10 40.1 0.0 4.7e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Asp_Glu_race PF01177.17 OAP63410.1 - 5.3e-19 68.9 0.0 6.2e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase NmrA PF05368.8 OAP63412.1 - 6.9e-36 123.6 0.1 8.3e-36 123.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP63412.1 - 1.6e-15 57.5 0.2 2.3e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP63412.1 - 1e-05 24.6 0.2 0.00049 19.1 0.1 2.3 1 1 1 2 2 2 1 Male sterility protein Epimerase PF01370.16 OAP63412.1 - 2.8e-05 23.6 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAP63412.1 - 0.0002 21.3 0.6 0.00037 20.4 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 OAP63412.1 - 0.00071 18.3 0.0 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAP63412.1 - 0.0039 16.8 0.5 0.012 15.3 0.2 1.9 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 OAP63412.1 - 0.011 14.6 0.1 0.23 10.3 0.1 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 OAP63412.1 - 0.043 13.7 0.2 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 OAP63412.1 - 0.11 12.8 0.1 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 OAP63412.1 - 0.11 11.4 0.2 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF3553 PF12073.3 OAP63412.1 - 0.13 11.5 0.1 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Zn_clus PF00172.13 OAP63413.1 - 0.0019 18.0 7.0 0.0057 16.5 4.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.18 OAP63414.1 - 4.7e-73 246.0 0.0 5.9e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 OAP63414.1 - 0.0054 16.0 0.0 0.035 13.4 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 OAP63414.1 - 0.05 13.9 0.0 1 9.6 0.0 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase PSRT PF07636.6 OAP63414.1 - 0.17 11.3 1.2 0.43 10.0 0.8 1.7 1 0 0 1 1 1 0 PSRT Sugar_tr PF00083.19 OAP63415.1 - 1.9e-97 326.6 25.8 2.3e-97 326.4 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63415.1 - 2.1e-23 82.6 25.5 2.1e-23 82.6 17.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP63416.1 - 1.7e-18 66.4 0.0 2.5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tic20 PF09685.5 OAP63418.1 - 5.9e-05 23.0 3.1 8.4e-05 22.5 2.2 1.1 1 0 0 1 1 1 1 Tic20-like protein Retinal PF15449.1 OAP63418.1 - 9.9 3.6 7.0 11 3.4 4.9 1.0 1 0 0 1 1 1 0 Retinal protein DASH_Duo1 PF08651.5 OAP63419.1 - 2.3e-28 97.5 3.0 4.1e-28 96.7 2.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 Flagellin_C PF00700.16 OAP63419.1 - 0.019 15.1 0.8 0.047 13.8 0.6 1.7 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Macoilin PF09726.4 OAP63419.1 - 1 7.5 13.9 1.3 7.1 9.6 1.1 1 0 0 1 1 1 0 Transmembrane protein CENP-H PF05837.7 OAP63419.1 - 2 8.6 11.4 2.2 8.5 1.4 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF745 PF05335.8 OAP63419.1 - 2.1 7.8 21.2 4 6.9 13.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF745) PcfK PF14058.1 OAP63419.1 - 2.6 8.1 13.3 0.52 10.4 4.6 2.1 2 0 0 2 2 2 0 PcfK-like protein Syntaxin-6_N PF09177.6 OAP63419.1 - 2.6 8.4 12.1 1.6 9.1 3.2 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2229 PF09989.4 OAP63419.1 - 3.3 7.1 8.7 0.78 9.1 2.0 2.0 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Spc7 PF08317.6 OAP63419.1 - 4.7 5.7 15.0 0.028 13.0 2.7 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2422 PF10337.4 OAP63419.1 - 5 5.7 9.9 6.3 5.4 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) GAGA_bind PF06217.7 OAP63419.1 - 6.1 6.7 9.1 8.5 6.2 6.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DDRGK PF09756.4 OAP63419.1 - 9 5.6 15.5 7.3 5.9 6.0 2.1 2 0 0 2 2 2 0 DDRGK domain DAGK_cat PF00781.19 OAP63420.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Not1 PF04054.10 OAP63421.1 - 5.2e-93 311.9 0.0 1.5e-92 310.4 0.0 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 OAP63421.1 - 3.1e-47 159.9 1.1 3.1e-47 159.9 0.7 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) DUF221 PF02714.10 OAP63422.1 - 1.1e-109 366.2 20.6 2.3e-109 365.1 12.8 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAP63422.1 - 5.5e-36 123.4 0.2 5.5e-36 123.4 0.1 3.0 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 OAP63422.1 - 9.3e-19 67.1 1.6 4e-18 65.0 0.2 2.2 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 OAP63422.1 - 1.3e-15 57.6 7.0 2.4e-15 56.7 4.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4212 PF13937.1 OAP63422.1 - 1.8 8.5 11.1 0.24 11.4 1.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Seipin PF06775.9 OAP63423.1 - 1.2e-50 171.8 1.5 1.5e-50 171.4 1.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) AMP-binding PF00501.23 OAP63424.1 - 2.7e-48 164.3 0.0 3.8e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP63424.1 - 9.6e-06 26.4 0.1 2.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain E1-E2_ATPase PF00122.15 OAP63425.1 - 6.5e-52 175.8 0.3 3.3e-51 173.5 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 OAP63425.1 - 1.5e-45 156.2 0.0 3.3e-45 155.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 OAP63425.1 - 5.5e-39 132.1 0.1 2.5e-11 43.5 0.0 4.8 5 0 0 5 5 5 4 Heavy-metal-associated domain HAD PF12710.2 OAP63425.1 - 6.3e-19 68.8 0.0 1.5e-18 67.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAP63425.1 - 0.00013 21.6 0.0 0.0079 15.8 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PBP_like PF12727.2 OAP63425.1 - 0.043 12.7 0.0 0.092 11.6 0.0 1.5 1 0 0 1 1 1 0 PBP superfamily domain Toxin-deaminase PF14424.1 OAP63425.1 - 0.2 11.6 1.4 20 5.1 0.0 3.3 3 1 0 3 3 3 0 The BURPS668_1122 family of deaminases PHD PF00628.24 OAP63426.1 - 2.8e-07 30.1 12.5 5.2e-07 29.2 8.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 OAP63426.1 - 0.029 14.0 13.8 0.099 12.3 5.9 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 OAP63426.1 - 0.64 9.3 11.3 2.1 7.7 7.8 1.9 1 1 0 1 1 1 0 PHD-finger AAA_12 PF13087.1 OAP63427.1 - 9.4e-31 106.7 0.0 2.3e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAP63427.1 - 5.8e-19 68.5 0.0 1.4e-18 67.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP63427.1 - 2.1e-05 24.1 0.0 9.2e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 OAP63427.1 - 0.00035 20.2 0.0 0.031 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 OAP63427.1 - 0.0034 16.6 0.0 0.035 13.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.13 OAP63427.1 - 0.0035 16.9 0.1 4.5 6.7 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 OAP63427.1 - 0.021 14.9 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 OAP63427.1 - 0.037 13.4 0.0 0.095 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 OAP63427.1 - 0.052 12.5 0.0 0.78 8.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 OAP63427.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ECH PF00378.15 OAP63428.1 - 8.6e-36 123.2 0.0 1.1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HET PF06985.6 OAP63429.1 - 4.4e-09 36.6 0.4 1.2e-06 28.6 0.0 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 OAP63430.1 - 3e-46 157.7 37.6 3e-46 157.7 26.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP63430.1 - 7.3e-08 31.4 16.5 7.3e-08 31.4 11.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAP63430.1 - 1.4e-06 26.8 3.0 2.3e-06 26.1 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 OAP63430.1 - 0.042 13.8 4.0 0.047 13.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) AAA_12 PF13087.1 OAP63432.1 - 5.1e-41 140.2 0.0 1e-40 139.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAP63432.1 - 1.6e-29 103.1 0.2 3.7e-29 101.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP63432.1 - 2.3e-08 33.6 0.1 8.3e-08 31.8 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 OAP63432.1 - 7.3e-05 21.9 0.0 0.17 10.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 OAP63432.1 - 0.00026 20.6 0.3 0.015 14.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 OAP63432.1 - 0.0078 16.3 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.10 OAP63432.1 - 0.029 14.1 0.0 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DZR PF12773.2 OAP63432.1 - 4.8 7.0 7.2 2.8 7.8 0.7 2.9 3 0 0 3 3 3 0 Double zinc ribbon Tannase PF07519.6 OAP63433.1 - 2.3e-102 343.1 0.7 3.2e-102 342.6 0.5 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 OAP63433.1 - 2.2e-06 27.0 0.1 1.7e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAP63433.1 - 1.1e-05 25.4 1.5 2.3e-05 24.4 1.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP63433.1 - 0.0083 15.7 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold APH PF01636.18 OAP63434.1 - 5.7e-11 42.6 0.1 1.5e-09 37.9 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAP63434.1 - 2e-08 34.0 0.0 3.1e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 OAP63434.1 - 0.054 12.8 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Fungal_trans PF04082.13 OAP63435.1 - 6.2e-31 107.2 0.0 1e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63435.1 - 1.1e-11 44.4 4.0 2e-11 43.6 2.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MscS_porin PF12795.2 OAP63435.1 - 0.22 10.7 0.6 0.48 9.6 0.1 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain p450 PF00067.17 OAP63436.1 - 1.3e-43 149.2 0.0 2.1e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 OAP63437.1 - 1.1e-23 83.9 0.0 1.6e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP63437.1 - 6.6e-10 38.4 0.4 0.00059 18.8 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP63437.1 - 4.9e-05 23.1 0.1 0.0059 16.3 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAP63437.1 - 0.0028 17.6 1.4 0.0057 16.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 OAP63437.1 - 0.0029 16.2 2.3 0.97 7.9 0.6 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.19 OAP63437.1 - 0.0081 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 OAP63437.1 - 0.035 13.9 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 OAP63437.1 - 0.057 12.2 0.0 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Glyoxalase PF00903.20 OAP63438.1 - 4.7e-10 39.5 0.0 6.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP63438.1 - 1.4e-07 32.0 0.0 2.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 OAP63438.1 - 0.039 13.9 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sugar_tr PF00083.19 OAP63439.1 - 4.8e-93 312.1 33.1 5.6e-93 311.9 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63439.1 - 4.5e-22 78.2 36.6 2.2e-19 69.3 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP63440.1 - 1e-19 70.4 0.2 1.8e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63440.1 - 1.1e-07 31.5 13.5 1.1e-07 31.5 9.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 OAP63440.1 - 1.8e-05 24.7 0.5 1.8e-05 24.7 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP63440.1 - 0.00067 19.8 0.8 0.00067 19.8 0.5 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAP63440.1 - 0.013 15.7 5.3 0.62 10.4 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Ketoacyl-synt_C PF02801.17 OAP63443.1 - 2.5e-15 56.3 0.0 3.6e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 OAP63443.1 - 0.00082 18.9 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ank_2 PF12796.2 OAP63444.1 - 7.6e-59 196.0 1.5 4.1e-12 46.2 0.0 7.3 4 1 4 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP63444.1 - 9.5e-51 169.3 2.2 1.3e-07 31.8 0.0 9.2 3 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP63444.1 - 6.7e-42 140.5 10.8 3.2e-08 33.5 0.0 8.8 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.25 OAP63444.1 - 2.1e-41 137.6 0.3 6.7e-05 22.4 0.0 12.5 12 1 0 12 12 12 7 Ankyrin repeat Ank_3 PF13606.1 OAP63444.1 - 4.3e-31 103.8 0.3 0.028 14.6 0.0 11.8 12 0 0 12 12 12 7 Ankyrin repeat SPRY PF00622.23 OAP63444.1 - 7.7e-14 51.8 0.1 4.6e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 SPRY domain NACHT PF05729.7 OAP63444.1 - 1e-06 28.4 0.1 2.7e-05 23.8 0.1 2.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP63444.1 - 0.0029 17.6 0.8 0.022 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 OAP63444.1 - 0.0044 17.1 0.1 0.61 10.2 0.0 3.2 3 0 0 3 3 3 1 RNA helicase RPOL_N PF14700.1 OAP63444.1 - 7.9 5.6 10.4 3.5 6.7 0.7 3.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase N-terminal LtrA PF06772.6 OAP63445.1 - 4.6e-18 65.2 12.7 7.1e-18 64.6 8.8 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) RTC4 PF14474.1 OAP63446.1 - 6.1e-26 90.7 0.0 1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain MIP PF00230.15 OAP63447.1 - 6.2e-31 107.6 5.7 8.2e-31 107.2 3.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein zf-B_box PF00643.19 OAP63448.1 - 0.03 14.2 2.7 0.047 13.5 1.8 1.2 1 0 0 1 1 1 0 B-box zinc finger RNA_polI_A34 PF08208.6 OAP63448.1 - 0.06 13.0 2.1 0.75 9.4 0.0 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2937 PF11157.3 OAP63449.1 - 0.005 16.1 2.1 0.0057 15.9 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2937) DUF1041 PF06292.12 OAP63449.1 - 0.0076 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) Atg14 PF10186.4 OAP63450.1 - 1.6e-64 217.7 1.5 2.1e-64 217.3 1.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF555 PF04475.7 OAP63450.1 - 0.036 14.0 0.2 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF555) zf-C3HC4_4 PF15227.1 OAP63450.1 - 0.23 11.3 1.6 0.44 10.4 1.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING AAA_23 PF13476.1 OAP63450.1 - 1.3 9.3 9.6 2.3 8.4 6.7 1.4 1 0 0 1 1 1 0 AAA domain Phlebovirus_NSM PF07246.6 OAP63450.1 - 8.8 5.3 12.0 15 4.6 8.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF2401 PF10287.4 OAP63451.1 - 3.5e-83 278.6 0.1 5.1e-83 278.1 0.1 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 OAP63451.1 - 4.1e-22 78.0 0.2 1.2e-21 76.5 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) MFS_1 PF07690.11 OAP63452.1 - 1.2e-34 119.5 26.5 1.8e-34 119.0 18.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.20 OAP63453.1 - 1.1e-28 100.1 0.0 1.6e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63453.1 - 5.4e-14 51.8 0.0 9.9e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pyr_redox_3 PF13738.1 OAP63454.1 - 2.7e-22 79.8 0.0 4.7e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP63454.1 - 9.2e-15 53.8 0.1 7e-13 47.6 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP63454.1 - 4.9e-13 48.7 0.1 1.8e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP63454.1 - 3.5e-11 43.3 0.0 1.6e-06 28.1 0.0 3.4 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP63454.1 - 1.2e-10 41.2 0.0 7.7e-09 35.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP63454.1 - 7e-07 28.4 0.2 0.073 11.9 0.0 4.3 5 0 0 5 5 5 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP63454.1 - 7.9e-06 25.7 1.4 0.019 14.7 0.1 4.3 3 2 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 OAP63454.1 - 1.3e-05 25.5 0.1 0.096 13.1 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 OAP63454.1 - 7.1e-05 22.8 0.1 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 1 NADH(P)-binding Thi4 PF01946.12 OAP63454.1 - 0.00012 21.3 0.2 0.0034 16.5 0.0 2.5 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.9 OAP63454.1 - 0.0018 16.8 0.3 0.11 10.9 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein 2-Hacid_dh_C PF02826.14 OAP63454.1 - 0.002 17.3 0.0 0.0054 15.9 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 OAP63454.1 - 0.0033 16.3 0.1 0.51 9.1 0.0 3.1 3 1 0 3 3 3 1 Glucose inhibited division protein A ApbA PF02558.11 OAP63454.1 - 0.0037 16.7 0.0 0.023 14.1 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 OAP63454.1 - 0.0045 17.2 0.9 0.19 11.9 0.3 3.2 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 OAP63454.1 - 0.0097 14.7 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_2 PF03446.10 OAP63454.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.8 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 OAP63454.1 - 0.02 15.0 0.2 0.25 11.4 0.0 2.4 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 OAP63454.1 - 0.023 13.8 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 OAP63454.1 - 0.041 13.5 0.2 0.13 11.8 0.0 2.0 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAP63454.1 - 0.062 13.7 0.1 0.37 11.2 0.0 2.3 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 OAP63454.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Phasin PF05597.6 OAP63454.1 - 0.11 12.3 0.0 0.5 10.1 0.0 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF896 PF05979.7 OAP63454.1 - 0.15 11.7 2.2 1.8 8.2 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) ThiF PF00899.16 OAP63454.1 - 0.19 11.5 0.2 1.2 9.0 0.0 2.4 3 0 0 3 3 2 0 ThiF family Aminotran_1_2 PF00155.16 OAP63455.1 - 1.1e-14 54.1 0.0 1.7e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 OAP63455.1 - 4.2e-05 22.3 0.0 9.2e-05 21.1 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 OAP63455.1 - 0.00042 19.4 0.0 0.0066 15.5 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family CBFD_NFYB_HMF PF00808.18 OAP63456.1 - 8.6e-30 102.5 0.9 1.2e-29 102.1 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAP63456.1 - 3.5e-07 30.2 0.0 5.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 OAP63456.1 - 0.00065 19.4 0.0 0.00095 18.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 OAP63456.1 - 0.0013 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 OAP63456.1 - 0.045 14.0 0.1 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A SH3_9 PF14604.1 OAP63458.1 - 2.9e-31 106.7 1.5 2.7e-15 55.6 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 OAP63458.1 - 3.6e-29 99.8 1.7 2.6e-14 52.3 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 OAP63458.1 - 1.2e-14 53.5 0.1 3e-07 29.8 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 OAP63458.1 - 4.3e-09 36.3 0.0 7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CPSase_L_D2 PF02786.12 OAP63459.1 - 1.6e-110 367.3 0.0 2.2e-84 281.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 OAP63459.1 - 3.8e-40 136.4 0.1 8.3e-40 135.3 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 OAP63459.1 - 5.9e-39 133.7 0.4 1.2e-21 77.2 0.1 3.0 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 OAP63459.1 - 9.9e-35 118.9 0.0 2.7e-16 59.6 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 OAP63459.1 - 3.3e-24 85.2 0.0 9e-10 37.7 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 OAP63459.1 - 6e-20 71.3 0.0 6.5e-09 35.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAP63459.1 - 2.7e-16 59.5 0.6 1.3e-07 31.2 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 OAP63459.1 - 1.3e-08 34.5 0.0 0.00016 21.2 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 OAP63459.1 - 1.9e-06 27.8 0.1 0.075 12.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 OAP63459.1 - 1.6e-05 24.5 0.1 0.027 14.0 0.1 2.8 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 OAP63459.1 - 0.00011 21.4 0.3 0.094 11.9 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain MGS PF02142.17 OAP63459.1 - 0.00051 19.9 0.0 0.0024 17.7 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain Epimerase PF01370.16 OAP63459.1 - 0.014 14.7 0.0 0.082 12.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AhpC-TSA PF00578.16 OAP63459.1 - 0.061 13.0 0.2 0.33 10.6 0.0 2.5 3 0 0 3 3 3 0 AhpC/TSA family KR PF08659.5 OAP63459.1 - 0.14 11.8 0.0 0.43 10.2 0.0 1.8 1 0 0 1 1 1 0 KR domain Fungal_trans PF04082.13 OAP63460.1 - 3e-25 88.5 0.2 4.8e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63460.1 - 1.3e-06 28.2 11.6 2.5e-06 27.2 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UAA PF08449.6 OAP63461.1 - 2.5e-74 249.9 0.5 3.5e-74 249.4 0.3 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 OAP63461.1 - 7.8e-08 32.1 2.6 7.8e-08 32.1 1.8 2.5 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 OAP63461.1 - 0.0067 16.4 28.5 0.19 11.7 4.1 4.1 3 1 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 OAP63461.1 - 0.0087 16.2 20.1 0.035 14.3 2.4 3.0 3 1 1 4 4 4 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 OAP63461.1 - 0.032 13.3 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-sugar transporter AAA PF00004.24 OAP63462.1 - 6.6e-51 171.9 0.0 2.1e-42 144.4 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAP63462.1 - 1e-07 32.1 0.1 4.5e-06 26.7 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 OAP63462.1 - 5.8e-07 29.0 0.0 3.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 OAP63462.1 - 7.7e-06 25.9 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 OAP63462.1 - 6.8e-05 22.9 0.0 0.088 12.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 OAP63462.1 - 0.00013 22.1 0.3 0.0038 17.3 0.1 3.1 3 1 0 3 3 1 1 AAA domain AAA_14 PF13173.1 OAP63462.1 - 0.00018 21.4 0.0 0.0045 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Bromodomain PF00439.20 OAP63462.1 - 0.00023 20.9 0.0 0.00059 19.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.9 OAP63462.1 - 0.00024 20.8 0.0 0.00096 18.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 OAP63462.1 - 0.00051 20.1 0.0 0.004 17.3 0.0 2.5 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.1 OAP63462.1 - 0.00068 19.0 0.0 0.0024 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 OAP63462.1 - 0.0014 18.2 0.1 0.023 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAP63462.1 - 0.0027 17.6 0.1 0.025 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 OAP63462.1 - 0.0039 17.4 0.2 0.025 14.8 0.0 2.5 2 0 0 2 2 2 1 ABC transporter TIP49 PF06068.8 OAP63462.1 - 0.004 15.9 0.0 0.0066 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 OAP63462.1 - 0.0047 16.4 0.0 1.1 8.7 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain Torsin PF06309.6 OAP63462.1 - 0.0052 16.6 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 1 Torsin AAA_19 PF13245.1 OAP63462.1 - 0.0071 16.0 0.0 0.033 13.9 0.1 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 OAP63462.1 - 0.013 15.7 0.0 0.078 13.2 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAP63462.1 - 0.018 15.8 2.4 0.04 14.7 0.0 2.9 3 0 0 3 3 1 0 AAA domain Mg_chelatase PF01078.16 OAP63462.1 - 0.023 13.8 0.1 0.063 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 OAP63462.1 - 0.024 14.3 0.6 0.14 11.8 0.1 2.6 2 1 0 2 2 2 0 NACHT domain PhoH PF02562.11 OAP63462.1 - 0.03 13.5 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RuvB_N PF05496.7 OAP63462.1 - 0.046 12.7 0.0 0.098 11.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 OAP63462.1 - 0.076 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 OAP63462.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 OAP63462.1 - 0.29 10.0 0.0 0.5 9.2 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF3336 PF11815.3 OAP63463.1 - 5.6e-46 155.6 2.2 9.4e-46 154.9 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 OAP63463.1 - 5.1e-20 72.2 0.1 2.5e-19 70.0 0.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4363 PF14276.1 OAP63463.1 - 0.058 13.0 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) LRR_4 PF12799.2 OAP63464.1 - 3e-17 61.8 15.2 5.5e-07 29.0 3.4 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAP63464.1 - 8.2e-11 41.4 18.1 1.6e-07 30.9 2.5 4.7 3 1 4 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 OAP63464.1 - 2.6e-06 26.7 15.0 0.21 11.7 0.8 6.5 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 OAP63464.1 - 7.2e-05 22.4 11.2 0.61 10.3 0.2 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 OAP63464.1 - 0.00046 19.9 8.9 14 6.3 0.1 6.5 7 0 0 7 7 7 2 Leucine rich repeat Metallophos PF00149.23 OAP63465.1 - 1.4e-44 151.8 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.16 OAP63466.1 - 9.8e-65 217.0 0.0 1.1e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 OAP63466.1 - 2.3e-09 36.4 0.1 8.6e-06 24.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 OAP63466.1 - 1.2e-07 31.1 0.0 1.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 OAP63466.1 - 3.8e-07 30.0 0.0 5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAP63466.1 - 4.8e-06 27.0 0.0 6.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 OAP63466.1 - 2e-05 24.0 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 OAP63466.1 - 0.00011 21.3 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAP63466.1 - 0.013 14.9 0.0 0.63 9.4 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 OAP63466.1 - 0.045 13.1 0.0 3.7 6.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 OAP63466.1 - 0.076 12.5 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2457 PF10446.4 OAP63467.1 - 5.3e-134 447.4 33.6 5.3e-134 447.4 23.3 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2457) ERp29 PF07749.7 OAP63468.1 - 0.17 12.5 2.1 3.7 8.2 0.8 2.7 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain FAA_hydrolase PF01557.13 OAP63469.1 - 1.7e-47 161.7 0.0 2.2e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ca_chan_IQ PF08763.6 OAP63469.1 - 0.046 12.9 0.4 0.078 12.2 0.3 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Glyoxalase PF00903.20 OAP63470.1 - 4.4e-06 26.7 3.8 3.9e-05 23.6 1.2 2.8 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP63470.1 - 1.8e-05 25.2 1.2 0.069 13.7 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 OAP63470.1 - 0.039 13.9 0.2 0.19 11.7 0.1 2.2 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rdx PF10262.4 OAP63471.1 - 3.5e-29 100.6 0.0 5.1e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Rdx family Fungal_trans PF04082.13 OAP63472.1 - 0.007 15.2 0.0 0.0082 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain G-gamma PF00631.17 OAP63474.1 - 1.8e-21 75.6 0.1 3.3e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 GGL domain Phage_B PF02304.10 OAP63474.1 - 0.053 13.8 1.6 0.1 12.8 1.1 1.5 1 0 0 1 1 1 0 Scaffold protein B Metal_resist PF13801.1 OAP63474.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.5 2 0 0 2 2 2 0 Heavy-metal resistance Rab5-bind PF09311.6 OAP63474.1 - 0.73 9.6 9.8 2.1 8.2 2.8 2.2 2 0 0 2 2 2 0 Rabaptin-like protein ADIP PF11559.3 OAP63474.1 - 1 9.2 7.8 1.7 8.5 2.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Peptidase_S49_N PF08496.5 OAP63474.1 - 1.5 8.5 4.0 0.56 9.9 1.1 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PCI PF01399.22 OAP63475.1 - 2.4e-10 40.6 4.8 4.8e-10 39.6 0.0 3.3 3 0 0 3 3 3 1 PCI domain SRR1 PF07985.7 OAP63477.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 SRR1 Acetyltransf_3 PF13302.1 OAP63478.1 - 4.9e-10 39.7 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP63478.1 - 0.0086 16.0 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family KGG PF10685.4 OAP63479.1 - 4e-26 90.3 19.9 9.9e-12 44.4 1.7 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif MFS_1 PF07690.11 OAP63480.1 - 3e-29 101.8 34.6 3e-29 101.8 24.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FAA_hydrolase PF01557.13 OAP63481.1 - 1.9e-59 200.7 0.0 2.4e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 OAP63482.1 - 3.9e-38 130.8 0.3 6.8e-38 130.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63482.1 - 1.4e-10 40.9 4.5 2.3e-10 40.1 3.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 OAP63482.1 - 0.17 11.8 1.3 0.66 9.9 0.8 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Lactamase_B PF00753.22 OAP63483.1 - 5.8e-10 39.1 3.3 1.9e-09 37.4 2.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP63483.1 - 2e-05 24.2 0.0 2.9e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP63483.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Amidohydro_2 PF04909.9 OAP63484.1 - 1.8e-37 129.4 0.0 2.1e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 OAP63484.1 - 0.039 13.1 0.0 0.076 12.2 0.0 1.6 1 0 0 1 1 1 0 TatD related DNase MFS_1 PF07690.11 OAP63485.1 - 1.7e-33 115.8 33.4 1.8e-32 112.4 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 OAP63486.1 - 1.1e-29 102.6 0.3 1.5e-29 102.1 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP63486.1 - 4.3e-19 68.2 1.1 1.2e-18 66.8 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP63486.1 - 6.6e-06 27.0 0.0 1.2e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1049 PF06305.6 OAP63487.1 - 0.00067 19.0 0.2 0.0013 18.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 OAP63487.1 - 0.0074 14.6 0.0 0.0096 14.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 OAP63487.1 - 0.009 15.3 0.7 0.021 14.1 0.0 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 OAP63487.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A DUF1180 PF06679.7 OAP63487.1 - 0.012 15.4 2.4 0.051 13.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TraL PF07178.6 OAP63487.1 - 0.015 15.2 0.5 0.043 13.8 0.1 1.8 2 0 0 2 2 2 0 TraL protein Plasmodium_Vir PF05795.6 OAP63487.1 - 0.11 11.6 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 OAP63487.1 - 0.32 9.2 2.7 0.37 9.0 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 OAP63487.1 - 4.6 5.2 13.6 5.6 4.9 9.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Patatin PF01734.17 OAP63488.1 - 1.4e-28 100.2 0.0 4e-28 98.7 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase FAD_binding_3 PF01494.14 OAP63489.1 - 3.1e-14 52.8 0.1 6.4e-14 51.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP63489.1 - 2.8e-13 49.4 0.3 5e-06 25.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP63489.1 - 1.5e-09 37.6 0.1 3.3e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP63489.1 - 9.6e-08 31.2 1.1 2e-07 30.2 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP63489.1 - 4e-06 26.8 1.1 1.2e-05 25.2 0.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP63489.1 - 4.3e-06 25.4 0.6 0.00013 20.6 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 OAP63489.1 - 3.3e-05 23.1 0.0 5.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP63489.1 - 3.5e-05 24.1 0.1 0.00049 20.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAP63489.1 - 3.9e-05 22.9 0.2 0.01 14.9 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 OAP63489.1 - 4.2e-05 22.6 1.2 0.00056 18.9 0.2 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 OAP63489.1 - 4.5e-05 22.5 0.4 0.00027 19.9 0.3 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 OAP63489.1 - 6e-05 21.8 3.0 0.011 14.3 0.0 2.3 1 1 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.12 OAP63489.1 - 0.00035 19.7 0.1 0.00073 18.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 OAP63489.1 - 0.0009 19.3 0.0 0.0017 18.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP63489.1 - 0.0023 17.7 0.2 0.0092 15.7 0.1 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 OAP63489.1 - 0.031 13.9 1.8 0.073 12.7 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 OAP63489.1 - 0.033 13.9 0.2 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AAA_27 PF13514.1 OAP63489.1 - 0.093 10.4 0.1 0.12 9.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain Cupin_2 PF07883.6 OAP63490.1 - 2.2e-24 84.7 0.5 3e-16 58.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 OAP63490.1 - 2.5e-07 30.4 0.2 0.0079 15.8 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 OAP63490.1 - 1.1e-06 27.9 0.0 0.018 14.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 OAP63490.1 - 3.4e-05 23.2 0.1 0.095 12.1 0.0 2.2 2 0 0 2 2 2 2 Cupin CENP-C_C PF11699.3 OAP63490.1 - 6.4e-05 22.8 0.0 0.00035 20.4 0.0 1.9 2 0 0 2 2 2 1 Mif2/CENP-C like ARD PF03079.9 OAP63490.1 - 0.039 13.8 0.0 0.21 11.5 0.0 2.1 3 0 0 3 3 3 0 ARD/ARD' family SPT2 PF08243.6 OAP63491.1 - 0.00014 22.1 22.5 0.00014 22.1 15.6 2.5 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 OAP63492.1 - 2.6e-27 95.0 11.7 3.1e-27 94.7 8.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RibD_C PF01872.12 OAP63492.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 RibD C-terminal domain Shadoo PF14999.1 OAP63492.1 - 0.47 10.3 7.4 0.63 9.8 5.2 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_S19 PF00203.16 OAP63493.1 - 2.2e-34 116.9 0.3 3.3e-34 116.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 HEAT_2 PF13646.1 OAP63494.1 - 0.044 14.0 0.2 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 HEAT repeats DUF4187 PF13821.1 OAP63495.1 - 1.4e-17 63.0 2.4 5e-17 61.2 1.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 OAP63495.1 - 5.6e-09 35.6 0.2 1.3e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 G-patch domain DUF732 PF05305.9 OAP63495.1 - 0.015 15.3 0.2 0.037 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF732) DUF3533 PF12051.3 OAP63496.1 - 8.5e-104 347.3 3.6 1e-103 347.0 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Nop14 PF04147.7 OAP63497.1 - 4.7e-255 848.5 24.3 5.5e-255 848.3 16.8 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.8 OAP63497.1 - 0.026 13.3 0.0 0.061 12.1 0.0 1.6 1 0 0 1 1 1 0 Noc2p family adh_short PF00106.20 OAP63498.1 - 5e-24 85.0 0.6 8e-24 84.4 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP63498.1 - 1.9e-18 67.1 0.1 2.5e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 OAP63498.1 - 6.2e-09 35.4 0.1 1.2e-08 34.4 0.1 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 OAP63498.1 - 4e-06 26.6 0.3 7.6e-06 25.7 0.1 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 OAP63498.1 - 0.00075 19.5 0.1 0.00097 19.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP63498.1 - 0.0084 15.3 0.1 0.018 14.2 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family ADH_zinc_N PF00107.21 OAP63498.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.16 OAP63498.1 - 0.011 15.2 0.1 0.024 14.0 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GntP_permease PF02447.11 OAP63498.1 - 0.012 14.1 0.1 0.015 13.7 0.1 1.1 1 0 0 1 1 1 0 GntP family permease Eno-Rase_NADH_b PF12242.3 OAP63498.1 - 0.022 14.5 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 OAP63498.1 - 0.052 12.9 0.2 0.25 10.7 0.0 2.1 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Sec66 PF09802.4 OAP63499.1 - 2e-61 206.6 0.0 2.6e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4407 PF14362.1 OAP63499.1 - 0.053 12.4 4.6 0.072 12.0 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med3 PF11593.3 OAP63499.1 - 0.16 11.1 4.9 0.21 10.8 3.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPR_MLP1_2 PF07926.7 OAP63499.1 - 1.2 8.8 4.7 0.28 10.9 0.6 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PPR_2 PF13041.1 OAP63500.1 - 4.3e-07 29.7 0.0 0.19 11.7 0.0 5.7 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 OAP63500.1 - 2.7e-06 27.2 7.7 5 7.6 0.0 7.7 9 0 0 9 9 9 2 Pentatricopeptide repeat domain Siah-Interact_N PF09032.6 OAP63500.1 - 0.028 14.4 0.5 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal HET PF06985.6 OAP63501.1 - 3.1e-06 27.3 0.3 5.5e-05 23.3 0.2 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ORC3_N PF07034.6 OAP63502.1 - 1.7e-23 83.1 1.4 4.3e-23 81.8 0.9 1.6 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus PBP1_TM PF14812.1 OAP63502.1 - 0.0098 16.1 7.2 0.031 14.5 5.0 1.8 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.11 OAP63502.1 - 0.012 14.5 1.6 0.023 13.7 1.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 OAP63502.1 - 0.035 13.7 4.3 0.11 12.0 3.0 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region TLP-20 PF06088.6 OAP63502.1 - 0.28 10.8 4.5 0.62 9.7 3.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CobT PF06213.7 OAP63502.1 - 2 7.4 11.4 4.9 6.2 7.9 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleoplasmin PF03066.10 OAP63502.1 - 3.2 7.2 9.6 6.2 6.3 6.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 OAP63502.1 - 4.3 5.2 10.0 8.5 4.2 7.0 1.4 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.21 OAP63503.1 - 0.011 16.0 1.5 0.011 16.0 1.1 7.9 7 1 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP63503.1 - 0.027 14.7 50.6 0.14 12.5 0.3 7.9 9 0 0 9 9 9 0 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP63504.1 - 2.3 8.7 28.9 0.7 10.3 0.6 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type Macoilin PF09726.4 OAP63505.1 - 4.5e-05 21.9 28.4 0.017 13.4 0.0 2.9 1 1 1 2 2 2 1 Transmembrane protein Filament PF00038.16 OAP63505.1 - 6 6.2 63.2 1 8.7 7.6 3.1 1 1 1 2 2 2 0 Intermediate filament protein Carb_kinase PF01256.12 OAP63507.1 - 3.2e-51 173.9 0.0 4.3e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Epimerase PF01370.16 OAP63508.1 - 6.5e-14 51.9 0.0 8.5e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP63508.1 - 4.6e-11 43.0 0.0 7.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP63508.1 - 2e-08 33.2 0.0 2.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAP63508.1 - 3.8e-05 22.7 0.0 0.00036 19.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 OAP63508.1 - 0.0075 15.5 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TGT_C1 PF14809.1 OAP63508.1 - 0.064 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation DUF3807 PF12720.2 OAP63509.1 - 8.1e-26 91.2 1.8 9.8e-26 90.9 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) E1-E2_ATPase PF00122.15 OAP63511.1 - 3.6e-67 225.7 0.3 3.6e-67 225.7 0.2 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 OAP63511.1 - 3.8e-23 83.0 0.0 1.5e-22 81.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAP63511.1 - 3.1e-13 50.3 0.0 6.6e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAP63511.1 - 3.6e-11 42.3 0.0 7.4e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAP63511.1 - 0.0016 18.0 0.1 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP63511.1 - 0.0024 17.7 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Abhydrolase_3 PF07859.8 OAP63513.1 - 1.3e-40 139.2 0.0 1.5e-29 103.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 OAP63513.1 - 2.6e-10 39.6 0.1 1e-09 37.7 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 OAP63513.1 - 0.15 11.4 0.0 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase tRNA-synt_2 PF00152.15 OAP63514.1 - 3.4e-76 256.1 0.1 5.4e-76 255.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 OAP63514.1 - 2.4e-17 62.7 0.0 3.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 OAP63514.1 - 0.011 15.5 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAP63514.1 - 0.014 14.6 0.5 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) WLM PF08325.5 OAP63515.1 - 2.5e-50 170.9 0.0 4.2e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 OAP63515.1 - 0.00024 20.1 0.3 0.00024 20.1 0.2 3.0 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 OAP63515.1 - 0.2 11.4 6.6 1.8 8.4 3.6 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF1776 PF08643.5 OAP63516.1 - 6.8e-58 196.1 0.0 8.6e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CcdB PF01845.12 OAP63516.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 CcdB protein Clr5 PF14420.1 OAP63517.1 - 1.6e-19 69.4 0.3 4.6e-19 68.0 0.2 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_2 PF07719.12 OAP63517.1 - 0.041 13.8 0.4 0.2 11.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Kdo PF06293.9 OAP63518.1 - 2.4e-05 23.4 0.0 3.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.1 OAP63518.1 - 3.6e-05 23.4 0.0 5.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.18 OAP63518.1 - 0.042 13.5 0.1 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.6 OAP63518.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 OAP63518.1 - 0.16 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain zf-H2C2_2 PF13465.1 OAP63520.1 - 7.1e-11 41.8 13.6 6e-06 26.2 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 OAP63520.1 - 5.4e-10 39.0 11.6 1.9e-05 24.7 3.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP63520.1 - 2e-07 30.8 8.3 0.00019 21.5 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 OAP63520.1 - 5.4e-06 26.4 1.5 1.8e-05 24.7 1.0 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAP63520.1 - 0.00011 22.1 2.1 0.00011 22.1 1.4 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAP63520.1 - 0.00024 20.8 7.5 0.0038 17.0 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 OAP63520.1 - 0.55 9.9 3.8 5.6 6.7 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 OAP63520.1 - 0.9 9.6 7.6 0.057 13.5 1.0 2.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 OAP63520.1 - 1.1 9.0 5.3 0.43 10.3 0.5 2.2 2 0 0 2 2 2 0 BED zinc finger SNARE PF05739.14 OAP63521.1 - 4.9e-06 26.1 1.4 4.9e-06 26.1 0.9 2.4 2 0 0 2 2 2 1 SNARE domain Sec1 PF00995.18 OAP63522.1 - 4.4e-122 408.5 0.0 5e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MobC PF05713.6 OAP63522.1 - 0.06 13.3 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) Exo_endo_phos PF03372.18 OAP63523.1 - 4.4e-09 36.6 0.0 5.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Zn_clus PF00172.13 OAP63524.1 - 7.6e-06 25.7 10.0 1.6e-05 24.6 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.16 OAP63525.1 - 2.6e-40 137.3 0.0 5.1e-40 136.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.5 OAP63525.1 - 2.5e-30 104.0 0.0 4.6e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 OAP63525.1 - 2.9e-26 90.8 0.2 5.1e-26 90.0 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 OAP63525.1 - 7.1e-14 50.9 2.5 7.1e-14 50.9 1.7 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 OAP63525.1 - 3e-05 24.1 0.0 5.3e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 OAP63525.1 - 0.00087 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain NAD_binding_7 PF13241.1 OAP63525.1 - 0.09 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 OAP63525.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAP63525.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.19 OAP63525.1 - 0.13 11.1 0.0 0.39 9.5 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ecm33 PF12454.3 OAP63525.1 - 0.16 11.8 2.3 0.32 10.8 1.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein RNA_pol_A_bac PF01000.21 OAP63526.1 - 2.5e-24 85.5 0.0 5.6e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 OAP63526.1 - 1.5e-15 56.0 0.0 2.6e-15 55.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 OAP63527.1 - 7.1e-133 441.7 0.0 1.1e-132 441.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Pkinase PF00069.20 OAP63528.1 - 9.6e-71 237.9 0.0 1.3e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63528.1 - 1.7e-36 125.6 0.0 2.7e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP63528.1 - 8.6e-05 21.6 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 OAP63528.1 - 0.00093 18.5 0.2 0.0035 16.7 0.0 2.0 1 1 1 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 OAP63528.1 - 0.0053 15.8 0.0 0.0099 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family 5_nucleotid PF05761.9 OAP63528.1 - 0.025 13.0 0.1 0.042 12.3 0.1 1.3 1 0 0 1 1 1 0 5' nucleotidase family adh_short_C2 PF13561.1 OAP63529.1 - 8.2e-26 91.2 0.0 1e-25 90.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP63529.1 - 6.9e-21 74.8 0.3 1.4e-20 73.9 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP63529.1 - 2.9e-08 33.5 0.4 7.2e-08 32.2 0.3 1.7 1 1 0 1 1 1 1 KR domain 4HBT_2 PF13279.1 OAP63530.1 - 3.7e-24 85.4 0.0 5.7e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 OAP63530.1 - 0.0035 17.4 0.0 0.0068 16.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Pal1 PF08316.6 OAP63531.1 - 1.7e-07 31.7 1.5 3.1e-07 30.9 0.2 2.1 3 0 0 3 3 3 1 Pal1 cell morphology protein HVSL PF09749.4 OAP63532.1 - 2e-71 239.8 0.0 2.5e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Mito_fiss_reg PF05308.6 OAP63532.1 - 0.9 8.8 4.7 0.36 10.1 1.5 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator Cgr1 PF03879.9 OAP63533.1 - 2.1e-36 124.4 26.2 2.6e-36 124.1 18.1 1.1 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 OAP63533.1 - 0.19 12.0 12.3 0.29 11.4 8.5 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF3140 PF11338.3 OAP63533.1 - 0.2 11.7 6.3 0.27 11.3 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) LTXXQ PF07813.7 OAP63533.1 - 0.47 10.9 13.2 0.12 12.8 7.3 1.5 2 0 0 2 2 2 0 LTXXQ motif family protein DUF262 PF03235.9 OAP63533.1 - 1.5 8.7 5.9 1.6 8.6 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF4419 PF14388.1 OAP63533.1 - 2.6 7.1 4.9 3.5 6.7 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) DDHD PF02862.12 OAP63533.1 - 4.1 7.1 7.5 4.5 7.0 5.2 1.1 1 0 0 1 1 1 0 DDHD domain AIF_C PF14721.1 OAP63533.1 - 4.4 7.5 6.4 6.6 6.9 4.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term GAGA_bind PF06217.7 OAP63533.1 - 6.2 6.7 11.4 6.9 6.5 7.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CCDC74_C PF14917.1 OAP63533.1 - 8.1 6.5 12.7 0.35 10.9 4.0 2.3 2 1 0 2 2 2 0 Coiled coil protein 74, C terminal Adeno_VII PF03228.9 OAP63533.1 - 8.5 6.9 12.2 15 6.1 8.5 1.4 1 0 0 1 1 1 0 Adenoviral core protein VII Mito_carr PF00153.22 OAP63534.1 - 2.2e-59 197.1 0.9 1.1e-22 79.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1925 PF09094.6 OAP63534.1 - 0.14 12.1 0.1 11 6.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1925) RRM_1 PF00076.17 OAP63536.1 - 3.2e-33 113.1 0.3 1.6e-18 66.1 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP63536.1 - 2.5e-30 104.2 0.4 9.4e-17 60.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Telomere_reg-2 PF10193.4 OAP63536.1 - 1e-22 80.5 0.0 3.9e-22 78.6 0.0 2.1 2 0 0 2 2 2 1 Telomere length regulation protein RRM_5 PF13893.1 OAP63536.1 - 1.4e-17 63.2 0.0 1e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAP63536.1 - 0.00045 19.9 0.1 0.53 10.0 0.0 2.9 2 0 0 2 2 2 2 Limkain b1 p450 PF00067.17 OAP63537.1 - 6.6e-62 209.5 0.0 8.4e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_11 PF13414.1 OAP63538.1 - 1.5e-25 88.6 5.1 2.7e-09 36.5 0.4 4.4 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 OAP63538.1 - 1.1e-23 81.7 1.3 1.9e-05 24.0 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAP63538.1 - 2e-21 74.1 5.4 0.00054 19.6 0.1 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAP63538.1 - 4.5e-18 64.1 3.9 5.8e-05 23.3 1.7 5.5 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAP63538.1 - 9e-17 59.8 2.0 0.012 15.7 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 OAP63538.1 - 3.4e-16 59.4 5.3 3.1e-05 24.4 2.0 4.7 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAP63538.1 - 8.5e-14 51.6 4.2 0.0021 18.3 0.4 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAP63538.1 - 9.3e-13 47.9 1.8 2.6e-06 27.2 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAP63538.1 - 1.7e-12 46.1 0.0 0.0025 17.4 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAP63538.1 - 5.7e-09 35.1 4.7 0.14 12.0 0.0 6.3 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 OAP63538.1 - 5.4e-08 32.8 7.3 0.001 19.1 0.1 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAP63538.1 - 8.3e-08 31.9 2.7 0.0013 18.4 0.9 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 OAP63538.1 - 7.9e-06 25.9 0.2 0.049 13.7 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 OAP63538.1 - 0.014 15.8 5.9 24 5.6 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 OAP63538.1 - 0.021 13.8 3.3 0.45 9.5 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TOM20_plant PF06552.7 OAP63538.1 - 0.03 13.8 2.9 2.1 7.9 0.0 4.1 4 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 OAP63538.1 - 0.048 13.5 0.5 1.4 8.8 0.0 3.3 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain CorA PF01544.13 OAP63539.1 - 0.0011 18.0 11.9 0.061 12.3 8.3 2.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PX PF00787.19 OAP63540.1 - 3.5e-18 65.4 0.6 1.3e-17 63.6 0.1 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 OAP63540.1 - 7.9e-14 51.4 7.1 1.6e-07 30.7 0.2 2.1 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.13 OAP63540.1 - 0.00014 21.4 4.2 0.00042 19.8 2.9 1.8 1 1 0 1 1 1 1 BAR domain ADIP PF11559.3 OAP63540.1 - 0.0081 16.0 4.0 0.22 11.4 0.1 3.0 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 OAP63540.1 - 0.021 15.5 1.9 1.5 9.5 0.0 3.4 4 0 0 4 4 4 0 Occludin homology domain DASH_Dad3 PF08656.5 OAP63540.1 - 0.033 13.8 0.1 0.23 11.1 0.0 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 DUF724 PF05266.9 OAP63540.1 - 0.099 12.2 1.3 0.33 10.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 OAP63540.1 - 1.8 8.1 3.6 3.1 7.3 0.4 2.2 2 1 0 2 2 2 0 IncA protein Dynamitin PF04912.9 OAP63541.1 - 1.5e-21 76.7 12.3 6.4e-12 44.9 0.1 3.3 2 1 0 2 2 2 2 Dynamitin FtsH_ext PF06480.10 OAP63541.1 - 0.0096 16.0 0.2 0.024 14.7 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular Phage_Gp23 PF10669.4 OAP63541.1 - 1.7 8.7 7.0 0.56 10.3 2.1 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) HWE_HK PF07536.9 OAP63541.1 - 2 8.9 13.8 0.36 11.3 0.8 3.8 2 1 2 4 4 4 0 HWE histidine kinase APG6 PF04111.7 OAP63541.1 - 6.3 5.7 16.3 0.29 10.1 5.1 2.7 2 1 2 4 4 4 0 Autophagy protein Apg6 Glyco_transf_22 PF03901.12 OAP63542.1 - 4.3e-34 118.2 20.4 5.6e-34 117.8 14.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Cupin_2 PF07883.6 OAP63543.1 - 2e-07 30.3 0.1 3.5e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain UCH PF00443.24 OAP63544.1 - 1.4e-61 207.9 0.0 1.4e-61 207.9 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAP63544.1 - 4.2e-30 105.1 4.0 6.5e-24 84.8 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase YSIRK_signal PF04650.12 OAP63544.1 - 0.00054 19.4 1.0 0.00095 18.6 0.7 1.4 1 0 0 1 1 1 1 YSIRK type signal peptide Peptidase_C98 PF15499.1 OAP63544.1 - 0.15 11.3 1.8 1.8 7.7 0.6 2.6 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4407 PF14362.1 OAP63544.1 - 1.2 8.0 8.9 1.7 7.5 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NusB PF01029.13 OAP63544.1 - 1.3 9.0 8.3 13 5.7 4.5 2.4 2 0 0 2 2 2 0 NusB family GBP_C PF02841.9 OAP63544.1 - 1.7 7.7 17.9 4.3 6.4 12.4 1.6 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain EF-hand_6 PF13405.1 OAP63545.1 - 7.5e-15 53.4 1.3 1.4e-05 24.5 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 OAP63545.1 - 1.5e-12 47.4 0.1 2.3e-09 37.2 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 OAP63545.1 - 1.7e-12 45.6 2.2 1.4e-05 23.9 0.0 4.7 4 1 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 OAP63545.1 - 3.7e-09 35.5 1.4 0.00025 20.2 0.1 3.8 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 OAP63545.1 - 2.8e-08 33.2 1.0 0.00038 20.0 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair ChaC PF04752.7 OAP63546.1 - 5.1e-45 153.6 0.1 3.8e-28 98.6 0.0 2.1 1 1 1 2 2 2 2 ChaC-like protein RRM_1 PF00076.17 OAP63547.1 - 1.4e-23 82.2 0.1 1.9e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP63547.1 - 1.5e-16 60.1 0.0 2.4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP63547.1 - 1e-10 41.2 0.0 1.4e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAP63547.1 - 0.0055 16.5 0.1 0.0083 15.9 0.1 1.3 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.3 OAP63547.1 - 0.11 12.2 0.1 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 CYTL1 PF15153.1 OAP63548.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytokine-like protein 1 Abhydrolase_5 PF12695.2 OAP63549.1 - 4.2e-05 23.3 0.2 7.8e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAP63549.1 - 0.0036 16.9 0.1 0.0036 16.9 0.1 2.2 2 1 0 3 3 3 1 alpha/beta hydrolase fold DUF915 PF06028.6 OAP63549.1 - 0.012 14.7 0.0 0.73 8.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 OAP63549.1 - 0.017 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3657 PF12394.3 OAP63549.1 - 0.021 14.8 1.0 0.047 13.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3657) DUF2305 PF10230.4 OAP63549.1 - 0.036 13.4 0.1 5.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Nnf1 PF03980.9 OAP63550.1 - 1.9e-23 82.5 4.2 1.9e-23 82.5 2.9 1.8 2 0 0 2 2 2 1 Nnf1 DUF4600 PF15372.1 OAP63550.1 - 0.00085 19.5 6.3 0.29 11.3 2.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4600) IncA PF04156.9 OAP63550.1 - 0.041 13.4 14.1 0.012 15.1 7.8 1.6 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 OAP63550.1 - 0.087 12.7 4.7 0.15 11.9 3.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 OAP63550.1 - 0.11 11.1 5.6 0.018 13.7 1.5 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 OAP63550.1 - 0.11 12.8 4.1 0.069 13.5 1.3 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Filament PF00038.16 OAP63550.1 - 0.14 11.6 10.2 0.088 12.2 6.0 1.4 1 1 0 1 1 1 0 Intermediate filament protein Cortex-I_coil PF09304.5 OAP63550.1 - 0.15 12.1 5.1 0.1 12.6 1.8 1.9 1 1 0 1 1 1 0 Cortexillin I, coiled coil FUSC PF04632.7 OAP63550.1 - 0.35 9.2 4.0 0.46 8.8 2.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MitMem_reg PF13012.1 OAP63550.1 - 0.47 10.5 3.6 0.41 10.7 0.3 2.2 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function CENP-F_leu_zip PF10473.4 OAP63550.1 - 1.3 8.8 13.2 0.12 12.2 6.1 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 OAP63550.1 - 2.3 7.0 7.3 3.7 6.4 5.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 OAP63550.1 - 3.9 7.5 6.2 3.8 7.5 1.8 2.5 2 0 0 2 2 2 0 bZIP transcription factor Phage_GP20 PF06810.6 OAP63552.1 - 2.8 7.3 7.4 0.14 11.6 0.3 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 MFS_1 PF07690.11 OAP63553.1 - 7.1e-21 74.2 21.3 7.1e-21 74.2 14.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SIR2 PF02146.12 OAP63554.1 - 8.2e-31 107.0 0.0 1.5e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF202 PF02656.10 OAP63555.1 - 4.5e-10 39.5 0.3 7.8e-10 38.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Cation_efflux PF01545.16 OAP63556.1 - 8.3e-78 261.3 5.9 3.1e-77 259.4 4.1 1.7 1 1 0 1 1 1 1 Cation efflux family Metallophos PF00149.23 OAP63557.1 - 2.3e-12 46.7 0.1 1.2e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ank_2 PF12796.2 OAP63558.1 - 2.1e-86 284.3 15.6 3.6e-17 62.4 0.1 7.5 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 OAP63558.1 - 3.1e-79 257.0 25.3 4.5e-07 29.3 0.1 12.8 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 OAP63558.1 - 1.1e-62 207.3 15.0 4.6e-12 46.0 0.0 9.0 6 2 2 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP63558.1 - 2.3e-56 186.5 24.1 8.5e-10 38.5 0.3 12.3 3 3 9 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP63558.1 - 1.4e-54 176.5 10.8 0.00034 20.5 0.2 12.9 12 0 0 12 12 12 10 Ankyrin repeat NACHT PF05729.7 OAP63558.1 - 1.5e-08 34.4 0.0 4.5e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP63558.1 - 1e-06 28.8 0.0 1e-06 28.8 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 OAP63558.1 - 0.00011 22.2 0.0 0.00062 19.9 0.0 2.3 1 0 0 1 1 1 1 AAA domain EspA PF03433.8 OAP63558.1 - 0.035 13.5 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 EspA-like secreted protein DUF1949 PF09186.6 OAP63558.1 - 0.051 13.1 0.6 9.6 5.9 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1949) Saccharop_dh PF03435.13 OAP63558.1 - 0.054 12.4 1.4 5.7 5.8 0.3 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase Tyrosinase PF00264.15 OAP63560.1 - 5.6e-48 164.0 5.4 5.6e-48 164.0 3.7 2.7 2 1 0 2 2 2 1 Common central domain of tyrosinase GPI-anchored PF10342.4 OAP63560.1 - 3.5e-14 53.0 0.3 3.5e-14 53.0 0.2 2.8 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ADIP PF11559.3 OAP63560.1 - 0.00025 20.9 30.7 0.027 14.3 5.4 2.5 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding RTBV_P46 PF06216.6 OAP63560.1 - 0.41 9.4 7.5 0.073 11.9 1.2 2.0 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein CENP-F_leu_zip PF10473.4 OAP63560.1 - 0.48 10.2 26.2 0.39 10.5 9.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 OAP63560.1 - 0.75 9.6 8.7 0.043 13.6 1.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF641 PF04859.7 OAP63560.1 - 1.3 8.8 21.8 0.33 10.7 2.3 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 OAP63560.1 - 5.6 7.3 19.9 1 9.7 7.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Crl PF07417.7 OAP63561.1 - 1.7e-06 27.7 0.3 2.7e-06 27.1 0.2 1.3 1 1 0 1 1 1 1 Transcriptional regulator Crl PGA2 PF07543.7 OAP63561.1 - 5.1e-06 26.3 0.2 7.1e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 Arylsulfotran_2 PF14269.1 OAP63563.1 - 1.4e-58 198.3 4.1 2.1e-58 197.8 2.9 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAP63563.1 - 1.4e-20 73.2 5.9 3.4e-20 72.0 4.1 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 OAP63563.1 - 0.023 14.1 0.0 0.9 8.9 0.0 3.0 2 1 1 3 3 3 0 PQQ-like domain HSP20 PF00011.16 OAP63563.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Hsp20/alpha crystallin family STT3 PF02516.9 OAP63564.1 - 6.8e-131 437.5 40.4 4.1e-126 421.7 26.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF2498 PF10692.4 OAP63564.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) RNase_T PF00929.19 OAP63565.1 - 1.5e-20 74.1 0.0 3e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Dict-STAT-coil PF09267.5 OAP63565.1 - 0.041 14.1 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil RRM_1 PF00076.17 OAP63566.1 - 5.5e-14 51.5 0.6 3e-12 45.9 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP63566.1 - 6.3e-12 45.1 0.0 3.5e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP63566.1 - 5.3e-10 39.1 0.1 2.7e-08 33.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Hid1 PF12722.2 OAP63566.1 - 8.6 3.8 7.6 12 3.4 5.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sds3 PF08598.6 OAP63567.1 - 4.4e-26 91.6 2.9 4.4e-26 91.6 2.0 3.5 2 2 0 2 2 2 1 Sds3-like Peptidase_S64 PF08192.6 OAP63567.1 - 5.2 5.2 12.4 8.4 4.5 8.6 1.3 1 0 0 1 1 1 0 Peptidase family S64 MFS_1 PF07690.11 OAP63568.1 - 1.7e-29 102.6 17.4 1.7e-29 102.6 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1576 PF07613.6 OAP63568.1 - 1.8 8.0 10.0 5.6 6.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1576) Amino_oxidase PF01593.19 OAP63569.1 - 3.9e-57 194.3 0.1 3.2e-41 141.8 0.0 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP63569.1 - 2.9e-13 49.6 0.3 6.8e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP63569.1 - 6.4e-07 28.5 0.1 0.0001 21.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAP63569.1 - 7.7e-07 28.4 0.4 1.2e-06 27.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 OAP63569.1 - 7.3e-06 25.0 1.3 1.4e-05 24.1 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 OAP63569.1 - 2.1e-05 24.1 1.0 5.1e-05 22.9 0.7 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 OAP63569.1 - 6.8e-05 22.8 0.1 0.00018 21.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP63569.1 - 0.00013 22.3 1.3 0.00077 19.8 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP63569.1 - 0.00014 21.0 0.2 0.00029 20.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 OAP63569.1 - 0.00024 20.1 0.1 0.0046 15.9 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 OAP63569.1 - 0.0004 18.9 0.2 0.00069 18.2 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 OAP63569.1 - 0.0004 19.3 0.9 0.00056 18.8 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAP63569.1 - 0.0012 18.9 0.2 0.0025 17.9 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 OAP63569.1 - 0.0042 17.1 0.1 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain 3HCDH_N PF02737.13 OAP63569.1 - 0.01 15.4 0.2 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 OAP63569.1 - 0.013 14.4 0.2 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 OAP63569.1 - 0.054 12.8 0.4 0.094 12.0 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 OAP63569.1 - 0.096 12.7 0.2 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 OAP63569.1 - 0.12 12.3 0.4 0.29 11.1 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.7 OAP63569.1 - 0.12 11.6 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_oxidored PF12831.2 OAP63569.1 - 0.21 10.6 1.4 0.33 9.9 1.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.20 OAP63571.1 - 2.6e-16 59.9 0.1 5.4e-16 58.9 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 OAP63571.1 - 2.4e-05 23.5 0.1 4.1e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 OAP63571.1 - 4.3e-05 23.2 0.0 7.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 OAP63571.1 - 0.00073 19.6 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 OAP63571.1 - 0.0013 18.0 0.2 0.0024 17.1 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family 3HCDH_N PF02737.13 OAP63571.1 - 0.0039 16.8 0.1 0.006 16.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 OAP63571.1 - 0.0058 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDI PF00996.13 OAP63571.1 - 0.14 10.4 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF336 PF03928.9 OAP63572.1 - 9.2e-32 109.6 1.1 1.1e-31 109.4 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) MFS_1 PF07690.11 OAP63574.1 - 2.2e-20 72.6 28.2 5.2e-11 41.8 4.9 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 OAP63574.1 - 0.00012 20.5 17.0 0.0005 18.5 1.7 3.8 3 1 1 4 4 4 3 MFS/sugar transport protein LacY_symp PF01306.14 OAP63574.1 - 0.001 17.7 4.4 0.0064 15.0 0.4 2.9 3 0 0 3 3 3 2 LacY proton/sugar symporter Kdo PF06293.9 OAP63577.1 - 0.0056 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 OAP63578.1 - 7.4e-20 71.2 0.0 2.2e-17 63.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 OAP63578.1 - 0.019 14.7 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold HET PF06985.6 OAP63579.1 - 3.4e-23 82.3 0.0 5.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Coiled-coil_56 PF09813.4 OAP63580.1 - 0.00018 21.4 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Cyclase PF04199.8 OAP63581.1 - 5.8e-10 39.1 0.0 8.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Tannase PF07519.6 OAP63582.1 - 6.1e-98 328.5 3.9 7.5e-98 328.2 2.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 OAP63582.1 - 0.00021 21.0 0.1 0.0031 17.2 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 OAP63583.1 - 5.2e-31 107.6 0.0 9.9e-31 106.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PilX_N PF14341.1 OAP63583.1 - 0.13 11.9 1.6 0.36 10.5 0.8 1.9 2 0 0 2 2 2 0 PilX N-terminal DUF3431 PF11913.3 OAP63584.1 - 1.2e-84 283.2 0.1 1.5e-84 282.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) zf-rbx1 PF12678.2 OAP63585.1 - 6.5e-13 48.6 0.4 1.4e-12 47.5 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 OAP63585.1 - 9.4e-10 38.1 7.3 4.9e-09 35.8 5.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAP63585.1 - 1.8e-06 27.5 2.8 3.1e-06 26.7 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP63585.1 - 1.6e-05 24.5 4.5 6.2e-05 22.5 1.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP63585.1 - 1.8e-05 24.6 2.3 1.8e-05 24.6 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP63585.1 - 0.00016 21.3 3.0 0.00054 19.6 2.2 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAP63585.1 - 0.00041 20.1 2.7 0.0015 18.3 1.8 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 OAP63585.1 - 0.0033 17.1 7.4 0.0093 15.6 5.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAP63585.1 - 0.068 13.0 1.5 0.14 12.0 1.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zip PF02535.17 OAP63585.1 - 0.3 10.0 1.7 0.74 8.7 1.2 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 OAP63585.1 - 4.1 6.1 11.3 7.7 5.2 7.8 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 OAP63585.1 - 6.4 6.0 9.9 13 5.0 6.8 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RCR PF12273.3 OAP63586.1 - 1.7e-06 28.6 12.5 3.5e-06 27.6 8.7 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red tRNA-synt_2c PF01411.14 OAP63588.1 - 1.3e-217 723.4 0.0 1.9e-217 722.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 OAP63588.1 - 2.8e-17 62.3 1.2 6.4e-17 61.1 0.8 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 OAP63588.1 - 2.5e-05 23.9 0.2 6.7e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 DHHA1 domain PolyA_pol_arg_C PF12626.2 OAP63588.1 - 0.019 14.6 0.5 0.038 13.6 0.4 1.4 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus KMP11 PF03037.11 OAP63588.1 - 0.39 11.3 3.9 1.1 9.8 2.7 1.8 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 GFA PF04828.9 OAP63589.1 - 2.5e-19 68.9 0.0 3.3e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme adh_short PF00106.20 OAP63591.1 - 4.9e-18 65.5 0.0 8.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP63591.1 - 1.4e-06 28.0 0.0 3.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Asp_Glu_race PF01177.17 OAP63592.1 - 1.3e-27 97.1 0.0 1.5e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.6 OAP63592.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 AroM protein CN_hydrolase PF00795.17 OAP63593.1 - 2.9e-20 72.4 0.0 1.2e-19 70.4 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_4 PF13147.1 OAP63594.1 - 2.9e-25 89.8 0.2 4.4e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 OAP63594.1 - 1.8e-14 53.2 2.8 7.1e-14 51.3 1.6 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 OAP63594.1 - 9.8e-14 51.7 1.6 3.1e-06 27.0 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 OAP63594.1 - 3.3e-10 39.7 0.3 4.8e-05 22.7 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 OAP63594.1 - 0.0011 19.0 0.6 0.0023 18.0 0.4 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain YdjC PF04794.7 OAP63594.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 YdjC-like protein Amidohydro_1 PF01979.15 OAP63595.1 - 6e-25 88.6 0.0 1.2e-11 44.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP63595.1 - 5.4e-17 61.3 0.1 1.8e-16 59.7 0.1 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 OAP63595.1 - 2.4e-12 47.5 0.5 7.8e-06 26.1 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 OAP63595.1 - 5.1e-06 25.9 0.4 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family RPN7 PF10602.4 OAP63596.1 - 4.7e-57 192.2 0.4 7.4e-57 191.5 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 OAP63596.1 - 4.5e-10 39.7 0.0 1.6e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 PCI domain DUF2225 PF09986.4 OAP63596.1 - 0.018 14.5 0.3 0.029 13.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_4 PF13894.1 OAP63597.1 - 2e-05 24.6 17.0 0.092 13.1 0.0 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP63597.1 - 0.0018 18.4 21.0 0.76 10.2 0.1 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 OAP63597.1 - 0.0021 17.8 0.5 0.12 12.3 0.4 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger CDC45 PF02724.9 OAP63597.1 - 0.047 11.7 2.8 0.068 11.2 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-met PF12874.2 OAP63597.1 - 0.068 13.3 1.9 3.4 7.9 0.4 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TT_ORF2 PF02957.10 OAP63597.1 - 0.078 13.6 4.8 0.11 13.1 2.0 2.2 1 1 1 2 2 2 0 TT viral ORF2 Nucleoplasmin PF03066.10 OAP63597.1 - 0.11 12.0 10.1 0.18 11.2 7.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 OAP63597.1 - 0.48 10.5 8.0 0.99 9.5 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-C2H2_jaz PF12171.3 OAP63597.1 - 1.5 9.0 5.3 30 4.9 0.6 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CENP-B_dimeris PF09026.5 OAP63597.1 - 2 8.6 12.1 3.9 7.7 7.5 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 OAP63597.1 - 4.4 7.1 6.8 9.4 6.0 4.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 OAP63597.1 - 5.8 6.4 9.6 9.5 5.7 6.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region ATP_transf PF09830.4 OAP63598.1 - 4.5e-21 74.4 0.0 7.3e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Tetradecapep PF08187.6 OAP63599.1 - 0.079 12.8 0.7 17 5.4 0.1 2.7 2 0 0 2 2 2 0 Myoactive tetradecapeptides family Sugar_tr PF00083.19 OAP63600.1 - 4.7e-69 233.1 26.1 5.8e-69 232.8 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63600.1 - 8.1e-20 70.8 30.0 8.1e-20 70.8 20.8 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily DAD PF02109.11 OAP63600.1 - 0.035 14.1 3.2 0.053 13.5 0.6 2.5 1 1 1 2 2 2 0 DAD family SNF2_N PF00176.18 OAP63602.1 - 5.3e-60 202.7 0.0 8.9e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP63602.1 - 6.4e-15 54.7 0.0 2.4e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_3 PF12836.2 OAP63602.1 - 0.00049 19.9 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DEAD PF00270.24 OAP63602.1 - 0.00078 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_2 PF12796.2 OAP63603.1 - 1.1e-27 96.1 0.0 1.6e-13 50.7 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP63603.1 - 1e-20 73.6 0.2 1e-06 29.0 0.0 5.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 OAP63603.1 - 6.4e-20 69.8 5.1 0.00085 19.0 0.0 7.7 5 3 2 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 OAP63603.1 - 3.1e-18 64.0 0.1 0.0017 18.4 0.0 6.4 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 OAP63603.1 - 1.5e-12 47.3 1.0 0.0014 18.7 0.0 5.7 3 2 3 6 6 6 4 Ankyrin repeats (many copies) VMA21 PF09446.5 OAP63604.1 - 1.3e-15 57.0 9.7 1.8e-15 56.5 6.7 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.4 OAP63605.1 - 6.4e-19 68.2 0.9 6.4e-19 68.2 0.6 2.7 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) G6PD_C PF02781.11 OAP63606.1 - 4.7e-134 445.8 0.0 6.4e-134 445.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 OAP63606.1 - 1.6e-64 217.5 0.0 2.8e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_L35Ae PF01247.13 OAP63607.1 - 5.5e-45 151.0 0.4 6.2e-45 150.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 OAP63607.1 - 0.00014 21.6 0.0 0.054 13.4 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain stn_TNFRSF12A PF12191.3 OAP63608.1 - 0.13 12.3 0.5 0.68 9.9 0.1 2.3 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MFS_2 PF13347.1 OAP63609.1 - 8.3e-11 40.9 4.6 8.3e-11 40.9 3.2 2.1 3 0 0 3 3 3 1 MFS/sugar transport protein Patched PF02460.13 OAP63609.1 - 1.8 6.3 4.2 0.95 7.2 1.3 1.6 2 0 0 2 2 2 0 Patched family Pyrophosphatase PF00719.14 OAP63610.1 - 1.2e-51 174.2 0.1 1.5e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 OAP63611.1 - 1.7e-43 148.6 0.0 1.7e-43 148.6 0.0 1.9 1 1 0 2 2 2 1 Dihydrouridine synthase (Dus) Sec20 PF03908.8 OAP63612.1 - 6.2e-11 41.8 0.1 6.2e-11 41.8 0.1 2.8 3 1 1 4 4 4 1 Sec20 AAA PF00004.24 OAP63613.1 - 2.3e-11 44.0 0.0 4.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 OAP63613.1 - 2.9e-09 36.7 0.0 3.5e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 OAP63613.1 - 4.1e-07 29.0 0.1 0.0002 20.2 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 OAP63613.1 - 2.1e-06 27.6 0.0 8.9e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 OAP63613.1 - 8.6e-06 25.9 0.0 6e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAP63613.1 - 9.2e-06 24.8 0.0 2.4e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAP63613.1 - 0.00013 22.0 0.2 0.00062 19.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 OAP63613.1 - 0.00017 21.2 0.0 0.00097 18.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAP63613.1 - 0.00022 20.4 0.0 0.0036 16.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 OAP63613.1 - 0.00032 20.3 0.0 0.001 18.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 OAP63613.1 - 0.0063 16.4 0.0 0.02 14.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.4 OAP63613.1 - 0.013 14.5 0.0 0.028 13.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 OAP63613.1 - 0.021 13.7 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 OAP63613.1 - 0.024 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAP63613.1 - 0.04 14.0 0.1 0.19 11.9 0.0 2.2 2 1 0 2 2 1 0 RNA helicase GVQW PF13900.1 OAP63613.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative binding domain SPAN-X PF07458.7 OAP63613.1 - 0.11 12.7 1.9 0.28 11.4 0.9 1.9 2 0 0 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome TBPIP PF07106.8 OAP63614.1 - 0.04 13.4 4.5 0.097 12.2 3.1 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HSP70 PF00012.15 OAP63615.1 - 3.1e-09 35.3 0.2 1.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Hsp70 protein DUF3431 PF11913.3 OAP63616.1 - 1.4e-84 283.0 0.2 1.9e-84 282.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF1746 PF08508.5 OAP63617.1 - 5.1e-13 48.9 6.5 2.5e-12 46.7 4.5 1.9 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.18 OAP63618.1 - 6.5e-68 227.9 0.1 8.4e-68 227.6 0.0 1.1 1 0 0 1 1 1 1 Clp protease TPR_2 PF07719.12 OAP63619.1 - 5.8e-05 22.7 2.3 0.0036 17.1 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAP63619.1 - 0.00012 21.9 0.3 0.00037 20.3 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP63619.1 - 0.00021 21.6 1.7 0.53 11.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAP63619.1 - 0.0014 19.1 1.9 0.015 15.9 0.6 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP63619.1 - 0.0019 18.5 1.3 0.013 15.8 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Clr5 PF14420.1 OAP63619.1 - 0.0031 17.3 0.8 0.0083 15.9 0.5 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_11 PF13414.1 OAP63619.1 - 0.0064 16.1 2.3 0.38 10.4 0.0 3.2 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.23 OAP63619.1 - 0.013 15.1 0.8 0.49 10.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAP63619.1 - 0.18 11.7 3.6 1.9 8.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1152 PF06626.7 OAP63620.1 - 0.0052 15.9 0.8 0.95 8.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1152) dCMP_cyt_deam_1 PF00383.17 OAP63621.1 - 1.2e-13 50.6 0.1 1.7e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 OAP63621.1 - 7e-07 29.2 0.3 1.5e-05 25.0 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 OAP63621.1 - 0.00082 18.8 0.6 0.13 11.6 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases COesterase PF00135.23 OAP63622.1 - 4.7e-27 94.9 0.3 2.8e-24 85.7 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP63622.1 - 0.0017 17.9 0.2 0.0049 16.4 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Acetyltransf_1 PF00583.19 OAP63623.1 - 1.9e-16 59.8 0.0 2.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 OAP63623.1 - 7.2e-09 35.2 0.0 1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 OAP63623.1 - 8.7e-09 35.4 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP63623.1 - 2.2e-06 27.7 0.0 3.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP63623.1 - 0.00014 21.8 0.1 0.00024 21.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP63623.1 - 0.00031 20.5 0.0 0.00047 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAP63623.1 - 0.00061 19.7 0.0 0.00084 19.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SOG2 PF10428.4 OAP63624.1 - 7 5.1 13.5 0.68 8.5 5.2 2.2 2 1 0 2 2 2 0 RAM signalling pathway protein But2 PF09792.4 OAP63625.1 - 4.8e-29 100.9 3.3 6.1e-29 100.6 2.3 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF4381 PF14316.1 OAP63626.1 - 0.34 11.0 4.3 0.71 9.9 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) DNAP_B_exo_N PF08452.5 OAP63626.1 - 2.4 7.4 4.6 15 4.9 0.1 2.8 3 0 0 3 3 3 0 DNA polymerase family B exonuclease domain, N-terminal GPI PF06560.6 OAP63628.1 - 0.041 12.8 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) MARVEL PF01284.18 OAP63629.1 - 2e-07 30.9 13.0 2.7e-07 30.5 9.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain HLH PF00010.21 OAP63630.1 - 1.8e-07 30.6 0.0 4.6e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PspB PF06667.7 OAP63630.1 - 0.017 15.0 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 Phage shock protein B Flavodoxin_5 PF12724.2 OAP63632.1 - 1.8e-24 86.3 0.0 2.5e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.20 OAP63632.1 - 6.2e-06 26.2 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.2 OAP63632.1 - 0.0034 16.8 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain RNase_H_2 PF13482.1 OAP63632.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily Flavodoxin_4 PF12682.2 OAP63632.1 - 0.048 13.0 0.0 0.12 11.6 0.0 1.7 1 1 1 2 2 2 0 Flavodoxin PaRep2b PF07775.6 OAP63632.1 - 0.074 11.2 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 PaRep2b protein Zn_clus PF00172.13 OAP63633.1 - 2.6e-07 30.4 15.3 4.5e-07 29.6 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.14 OAP63634.1 - 1.3e-26 93.1 0.3 1.7e-26 92.7 0.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4149 PF13664.1 OAP63634.1 - 0.13 12.2 1.7 1.2 9.2 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Brix PF04427.13 OAP63635.1 - 1.3e-28 99.9 0.0 1.9e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Transferase PF02458.10 OAP63636.1 - 2.1e-24 85.7 0.0 1e-22 80.1 0.0 2.0 2 0 0 2 2 2 2 Transferase family Sulfotransfer_3 PF13469.1 OAP63637.1 - 5.6e-07 30.6 0.2 8e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Arylsulfotran_2 PF14269.1 OAP63638.1 - 3.1e-57 193.9 3.1 4.7e-57 193.4 2.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAP63638.1 - 1.8e-14 53.1 2.9 1.2e-13 50.3 2.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 OAP63639.1 - 8.4e-17 60.9 9.5 8.4e-17 60.9 6.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 OAP63640.1 - 2.7e-24 83.6 48.1 0.00073 19.7 0.5 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP63640.1 - 4.4e-24 83.3 58.8 0.00025 21.1 0.3 10.0 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP63640.1 - 3.5e-14 52.2 67.4 1.2e-05 25.3 2.0 10.5 11 0 0 11 11 11 7 Zinc-finger double domain zf-Di19 PF05605.7 OAP63640.1 - 0.0001 22.3 42.1 0.01 15.9 0.1 7.4 5 2 2 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 OAP63640.1 - 0.0032 17.5 19.1 0.86 9.8 0.0 6.8 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 OAP63640.1 - 0.0072 15.8 11.1 0.025 14.1 0.2 4.3 5 0 0 5 5 5 1 GAGA factor zf-met PF12874.2 OAP63640.1 - 0.11 12.7 18.9 0.14 12.4 0.0 7.4 9 0 0 9 9 9 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 OAP63640.1 - 3.6 8.0 44.6 0.13 12.5 0.3 9.4 9 1 0 9 9 9 0 C2H2-type zinc-finger domain RNA_pol_Rpb6 PF01192.17 OAP63641.1 - 1.8e-24 85.2 0.2 3.1e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Merozoite_SPAM PF07133.6 OAP63641.1 - 0.11 12.4 2.0 0.12 12.2 1.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Abhydrolase_6 PF12697.2 OAP63643.1 - 1.6e-18 67.4 0.1 2.1e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP63643.1 - 1.3e-14 53.8 0.0 2.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 OAP63643.1 - 2.5e-13 50.0 0.0 4.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 OAP63643.1 - 0.00029 20.1 0.0 0.16 11.2 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 OAP63643.1 - 0.00046 19.6 0.0 4.7 6.6 0.0 3.2 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 OAP63643.1 - 0.00084 18.6 0.0 0.73 9.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAP63643.1 - 0.0019 17.7 0.1 0.0048 16.4 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 OAP63643.1 - 0.0026 17.2 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF1749 PF08538.5 OAP63643.1 - 0.04 12.7 0.0 0.087 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Chlorophyllase PF07224.6 OAP63643.1 - 0.044 12.5 0.2 0.21 10.3 0.2 1.9 1 1 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 OAP63643.1 - 0.049 12.5 0.1 0.59 8.9 0.1 2.3 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.6 OAP63643.1 - 0.053 12.5 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) WD40 PF00400.27 OAP63644.1 - 0.0038 17.0 12.8 0.73 9.8 0.1 5.5 7 0 0 7 7 7 3 WD domain, G-beta repeat SNase PF00565.12 OAP63645.1 - 2.9e-24 85.4 0.2 4.6e-24 84.7 0.2 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Pex14_N PF04695.8 OAP63645.1 - 0.02 14.9 0.4 0.039 13.9 0.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.9 OAP63646.1 - 2.3 6.1 6.9 3.8 5.4 4.8 1.4 1 0 0 1 1 1 0 CDC45-like protein TauD PF02668.11 OAP63647.1 - 1.4e-54 185.5 0.1 1.6e-54 185.3 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2414 PF10309.4 OAP63648.1 - 4.4e-18 64.7 0.8 7.8e-18 63.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 OAP63648.1 - 0.002 18.0 0.1 0.0038 17.1 0.1 1.4 1 0 0 1 1 1 1 RNA binding domain DUF605 PF04652.11 OAP63649.1 - 5.7e-91 305.7 31.4 4.1e-90 302.9 21.8 2.1 1 1 0 1 1 1 1 Vta1 like MMR_HSR1 PF01926.18 OAP63650.1 - 3.3e-05 23.8 0.0 7.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 OAP63650.1 - 0.0034 18.2 0.8 0.0091 16.8 0.1 2.2 2 1 0 2 2 1 1 AAA domain AIG1 PF04548.11 OAP63650.1 - 0.0035 16.4 0.0 0.007 15.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family ArgK PF03308.11 OAP63650.1 - 0.005 15.6 1.1 0.025 13.3 0.1 2.3 3 0 0 3 3 3 1 ArgK protein T2SE PF00437.15 OAP63650.1 - 0.007 15.2 0.2 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Miro PF08477.8 OAP63650.1 - 0.0087 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_18 PF13238.1 OAP63650.1 - 0.016 15.4 0.1 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAP63650.1 - 0.023 14.6 0.4 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 OAP63650.1 - 0.031 13.7 0.9 0.064 12.7 0.7 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 OAP63650.1 - 0.036 14.3 0.2 0.09 13.0 0.2 1.6 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 OAP63650.1 - 0.036 13.0 0.2 0.064 12.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 OAP63650.1 - 0.046 14.0 1.0 0.096 12.9 0.7 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAP63650.1 - 0.049 13.7 0.2 0.4 10.8 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 OAP63650.1 - 0.07 12.3 0.5 0.19 10.8 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAP63650.1 - 0.075 12.4 0.1 0.19 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain zf-C2H2_jaz PF12171.3 OAP63651.1 - 2.7e-10 40.0 18.5 0.002 18.2 1.0 6.3 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP63651.1 - 1.2e-07 31.6 19.0 0.29 11.3 0.5 6.4 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 OAP63651.1 - 1.5e-07 31.3 32.9 0.0044 17.2 0.7 7.0 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP63651.1 - 4.4e-06 26.6 22.8 0.024 14.9 0.3 7.0 7 0 0 7 7 7 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAP63651.1 - 0.00012 21.8 0.1 0.00012 21.8 0.1 6.0 7 0 0 7 7 7 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 OAP63651.1 - 0.00029 20.8 4.8 0.00029 20.8 3.3 5.0 2 1 3 5 5 5 3 C2H2 type zinc-finger (2 copies) GATA PF00320.22 OAP63651.1 - 0.00085 18.6 2.2 0.068 12.5 0.1 3.3 3 0 0 3 3 3 1 GATA zinc finger DUF4187 PF13821.1 OAP63651.1 - 0.0016 17.9 3.5 1.7 8.3 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4187) HypA PF01155.14 OAP63651.1 - 0.15 11.7 15.2 0.16 11.6 0.2 4.2 2 1 2 4 4 4 0 Hydrogenase expression/synthesis hypA family DUF35_N PF12172.3 OAP63651.1 - 0.54 10.2 0.0 0.54 10.2 0.0 4.0 5 1 0 5 5 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rep_fac-A_C PF08646.5 OAP63651.1 - 0.8 9.3 7.1 8.1 6.1 0.0 4.0 3 1 0 3 3 3 0 Replication factor-A C terminal domain TPR_11 PF13414.1 OAP63652.1 - 3.8e-09 36.0 1.7 6.8e-09 35.2 0.3 2.0 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAP63652.1 - 6.8e-08 31.8 1.6 0.0045 16.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAP63652.1 - 3.1e-07 29.7 1.5 0.00024 20.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 OAP63652.1 - 3.7e-05 23.7 3.0 7.2e-05 22.8 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 OAP63652.1 - 0.004 17.7 4.2 4.9 7.9 2.5 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAP63652.1 - 0.012 15.9 0.8 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAP63652.1 - 0.047 13.5 1.2 1.1 9.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP63652.1 - 0.15 12.0 1.8 3.3 7.7 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.20 OAP63653.1 - 2.2e-15 56.7 0.1 2.8e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP63653.1 - 7.2e-11 42.6 0.0 1.1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 OAP63653.1 - 0.0014 18.6 0.0 0.0035 17.3 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 OAP63653.1 - 0.06 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 CppA N-terminal Hanta_G2 PF01561.11 OAP63653.1 - 0.11 10.8 0.1 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 EthD PF07110.6 OAP63654.1 - 3.6e-19 69.4 0.2 6.6e-19 68.6 0.2 1.4 1 1 0 1 1 1 1 EthD domain SpoIIE PF07228.7 OAP63655.1 - 1.5e-10 41.0 0.1 7.5e-10 38.8 0.1 2.0 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 OAP63655.1 - 2.4e-09 36.9 0.0 5.2e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 OAP63655.1 - 4.2e-08 32.9 0.0 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C p450 PF00067.17 OAP63656.1 - 4.9e-97 325.3 0.0 5.9e-97 325.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PCI PF01399.22 OAP63657.1 - 3.6e-14 52.9 0.0 1e-13 51.4 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 OAP63657.1 - 0.0026 18.0 7.5 0.0035 17.6 0.7 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Aldedh PF00171.17 OAP63658.1 - 2.2e-148 494.4 0.0 2.4e-148 494.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2188 PF09954.4 OAP63658.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) GFO_IDH_MocA PF01408.17 OAP63659.1 - 1e-20 74.4 0.0 2.2e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 OAP63659.1 - 0.041 14.1 0.2 1.9 8.8 0.0 3.0 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain ABC_membrane PF00664.18 OAP63660.1 - 2.9e-79 266.3 37.9 3.5e-42 144.7 10.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAP63660.1 - 8.2e-69 230.2 0.0 4.2e-33 114.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAP63660.1 - 7.7e-13 49.0 0.0 0.014 15.3 0.0 4.3 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 OAP63660.1 - 1.5e-12 47.2 0.7 0.00023 20.4 0.3 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 OAP63660.1 - 4.7e-12 45.2 2.2 0.00027 19.6 0.0 4.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 OAP63660.1 - 1.6e-10 41.2 2.6 5.9e-05 23.1 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 OAP63660.1 - 9.4e-09 34.6 0.0 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAP63660.1 - 4.6e-08 32.4 0.9 0.0025 17.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAP63660.1 - 3.6e-06 26.5 2.1 0.023 14.1 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAP63660.1 - 5.2e-06 26.6 3.1 0.12 12.5 0.2 4.0 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAP63660.1 - 7.7e-06 26.7 0.0 0.18 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 OAP63660.1 - 3.7e-05 23.5 3.6 0.052 13.4 0.3 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 OAP63660.1 - 8.7e-05 22.5 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 OAP63660.1 - 0.00029 20.7 0.0 0.68 9.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 OAP63660.1 - 0.00044 19.9 0.6 3.6 7.3 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAP63660.1 - 0.001 18.9 0.0 1.9 8.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 OAP63660.1 - 0.005 16.3 1.1 4 6.7 0.1 3.4 4 0 0 4 4 4 1 AAA-like domain AAA_18 PF13238.1 OAP63660.1 - 0.0051 17.1 0.0 3.2 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 OAP63660.1 - 0.0056 16.2 0.2 1.2 8.6 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 OAP63660.1 - 0.01 15.7 0.0 9.2 6.2 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 OAP63660.1 - 0.015 15.4 0.1 7.3 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 OAP63660.1 - 0.019 14.6 0.0 7.3 6.2 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dala_Dala_lig_N PF01820.16 OAP63660.1 - 0.038 14.2 0.0 0.67 10.2 0.0 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus NACHT PF05729.7 OAP63660.1 - 0.039 13.6 0.4 8.5 6.0 0.1 2.9 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 OAP63660.1 - 0.043 12.7 0.0 5.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.15 OAP63660.1 - 0.064 11.9 0.0 7.1 5.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.1 OAP63660.1 - 0.07 13.4 0.1 6.2 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 OAP63660.1 - 0.082 13.1 1.6 68 3.6 0.2 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2753 PF10952.3 OAP63660.1 - 0.13 12.2 0.0 5.1 7.0 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2753) Miro PF08477.8 OAP63660.1 - 0.17 12.3 0.0 36 4.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein SRF-TF PF00319.13 OAP63661.1 - 1.2e-23 82.1 0.1 1.8e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.6 OAP63662.1 - 7.2e-149 496.1 0.0 1.1e-148 495.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) PX PF00787.19 OAP63663.1 - 3.5e-21 75.1 0.0 5.8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 PX domain Pkinase PF00069.20 OAP63665.1 - 1.8e-47 161.6 0.0 2.8e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63665.1 - 2.9e-18 65.8 0.0 4.3e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP63665.1 - 0.00028 19.9 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 OAP63665.1 - 0.0013 18.1 0.3 0.0023 17.3 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 OAP63665.1 - 0.018 14.1 0.3 0.042 12.9 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 OAP63665.1 - 0.042 13.4 0.1 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase UPF0261 PF06792.6 OAP63666.1 - 3e-146 487.0 1.8 3.6e-146 486.7 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 OAP63667.1 - 2.3e-135 449.8 0.4 2.7e-135 449.6 0.3 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 OAP63667.1 - 1.2e-05 24.5 0.1 1.7e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase RNA_pol_Rpb4 PF03874.11 OAP63669.1 - 5.1e-17 61.9 0.1 6.2e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Met_10 PF02475.11 OAP63671.1 - 6.9e-64 215.1 0.0 1.1e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cupin_2 PF07883.6 OAP63672.1 - 0.0005 19.5 1.5 0.0014 18.1 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 OAP63672.1 - 0.0011 18.3 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 OAP63672.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 OAP63672.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.14 OAP63672.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 AraC-like ligand binding domain 2OG-FeII_Oxy_2 PF13532.1 OAP63673.1 - 2.3e-28 99.3 0.0 3.8e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TetR_C_6 PF13977.1 OAP63674.1 - 0.023 14.7 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor DUF2235 PF09994.4 OAP63675.1 - 3.1e-66 223.5 0.0 3.9e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PhoD PF09423.5 OAP63676.1 - 7.5e-08 31.3 0.1 5.7e-07 28.4 0.1 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.17 OAP63677.1 - 7.9e-51 172.8 1.3 1.1e-50 172.4 0.9 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 OAP63677.1 - 1.1e-27 95.6 0.2 2e-27 94.7 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain SAS4 PF15460.1 OAP63678.1 - 1.1e-32 111.9 7.1 2.3e-32 110.8 4.9 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Peptidase_S41 PF03572.13 OAP63679.1 - 5e-07 29.2 0.0 1.9e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 A_deaminase PF00962.17 OAP63680.1 - 3e-109 364.9 0.1 4.2e-109 364.4 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF4355 PF14265.1 OAP63682.1 - 0.2 11.5 13.5 0.56 10.1 9.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) APG6 PF04111.7 OAP63682.1 - 1.1 8.2 6.8 1.4 7.9 4.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cyclin PF08613.6 OAP63683.1 - 2e-34 119.1 0.0 2.9e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAP63683.1 - 0.047 13.2 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Sugar_tr PF00083.19 OAP63684.1 - 1.1e-76 258.2 19.2 1.3e-76 258.0 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63684.1 - 8.8e-11 41.1 31.1 2.3e-08 33.1 6.6 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Herpes_glycop_D PF01537.12 OAP63686.1 - 0.099 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain SLH PF00395.15 OAP63687.1 - 0.0017 18.0 0.0 0.3 10.8 0.1 2.5 2 0 0 2 2 2 2 S-layer homology domain ProRS-C_1 PF09180.6 OAP63687.1 - 0.0076 16.1 0.7 0.017 15.0 0.5 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal zf-C2H2_4 PF13894.1 OAP63687.1 - 0.017 15.4 14.1 1.4 9.4 1.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Prenyltransf PF01255.14 OAP63688.1 - 0.04 13.0 0.0 2.2 7.3 0.0 2.9 2 1 0 2 2 2 0 Putative undecaprenyl diphosphate synthase Mito_carr PF00153.22 OAP63689.1 - 3.3e-67 222.2 1.6 2e-21 75.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DRMBL PF07522.9 OAP63690.1 - 1.6e-34 118.2 0.0 3.8e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 OAP63690.1 - 1.4e-09 37.7 0.0 2.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LSM PF01423.17 OAP63691.1 - 1.2e-15 56.7 0.5 1.6e-15 56.4 0.3 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L30 PF00327.15 OAP63691.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e SM-ATX PF14438.1 OAP63691.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Abhydro_lipase PF04083.11 OAP63692.1 - 1.1e-19 69.5 0.0 4.5e-19 67.5 0.0 2.1 2 1 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 OAP63692.1 - 2.9e-08 33.8 2.1 6.4e-08 32.7 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP63692.1 - 0.00015 21.4 0.1 0.00044 19.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP63692.1 - 0.00074 19.2 0.0 0.0014 18.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AA_permease_2 PF13520.1 OAP63693.1 - 5.6e-59 199.7 47.6 7.1e-59 199.4 33.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP63693.1 - 2.1e-14 52.7 37.2 2.8e-14 52.3 25.8 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_S10 PF00450.17 OAP63694.1 - 6e-82 276.0 0.1 8.6e-82 275.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase VRR_NUC PF08774.6 OAP63695.1 - 1.4e-14 53.9 0.0 3.6e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Mito_carr PF00153.22 OAP63696.1 - 3.5e-75 247.8 0.1 3.9e-25 87.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 OAP63696.1 - 4e-17 60.5 4.5 1.4e-07 30.8 0.0 6.0 6 0 0 6 6 6 3 EF-hand domain EF-hand_7 PF13499.1 OAP63696.1 - 2.6e-15 56.3 4.2 2.1e-06 27.7 0.0 4.8 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 OAP63696.1 - 2.9e-14 51.1 3.5 2.5e-07 29.4 0.0 5.5 6 0 0 6 6 6 2 EF hand EF-hand_5 PF13202.1 OAP63696.1 - 4e-09 35.4 3.3 0.00017 20.7 0.1 5.1 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 OAP63696.1 - 2e-08 33.7 0.5 0.28 10.8 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 OAP63696.1 - 0.008 16.0 0.1 12 5.8 0.0 3.7 3 1 0 3 3 3 1 EF-hand domain BCNT PF07572.7 OAP63696.1 - 0.15 11.9 0.3 85 3.1 0.0 3.2 3 0 0 3 3 3 0 Bucentaur or craniofacial development Myb_DNA-bind_6 PF13921.1 OAP63697.1 - 4.2e-05 23.5 0.9 9.8e-05 22.3 0.6 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Abi_C PF14355.1 OAP63697.1 - 0.012 15.5 0.2 0.026 14.4 0.0 1.5 2 0 0 2 2 2 0 Abortive infection C-terminus Phage_fiber PF03335.8 OAP63697.1 - 2.1 8.3 4.5 1.3 8.9 0.3 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat RRM_1 PF00076.17 OAP63699.1 - 7.5e-21 73.5 0.0 1.1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP63699.1 - 1.1e-16 60.5 0.0 1.6e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP63699.1 - 1.7e-10 40.5 0.0 2.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H_2 PF13832.1 OAP63700.1 - 9.9e-35 118.8 1.9 9.9e-35 118.8 1.3 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAP63700.1 - 3e-27 94.5 0.6 3e-27 94.5 0.4 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 OAP63700.1 - 9.4e-21 74.7 0.0 5.1e-20 72.3 0.0 2.4 1 1 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 OAP63700.1 - 1.8e-14 52.7 3.2 5.2e-14 51.2 2.2 1.8 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 OAP63700.1 - 1.4e-08 34.2 25.0 5.7e-08 32.3 6.8 2.7 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 OAP63700.1 - 0.02 14.2 3.2 0.058 12.6 2.2 1.8 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 OAP63700.1 - 0.072 12.8 12.9 0.94 9.2 0.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_S13_N PF08069.7 OAP63702.1 - 8.1e-28 96.0 0.1 1.5e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 OAP63702.1 - 1.1e-21 76.4 0.1 1.5e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 OAP63702.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain Dpy-30 PF05186.8 OAP63703.1 - 0.0029 17.0 0.0 0.011 15.2 0.0 1.9 1 1 0 1 1 1 1 Dpy-30 motif SSFA2_C PF14723.1 OAP63703.1 - 0.064 12.9 1.2 0.096 12.4 0.9 1.2 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus PAT1 PF09770.4 OAP63703.1 - 5.8 5.0 12.4 6.8 4.7 8.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans_2 PF11951.3 OAP63706.1 - 5.5e-39 133.8 0.0 7.2e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain SnoaL_2 PF12680.2 OAP63706.1 - 0.047 14.0 0.1 0.18 12.2 0.1 1.9 1 0 0 1 1 1 0 SnoaL-like domain adh_short PF00106.20 OAP63707.1 - 1.5e-14 54.2 0.1 3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP63707.1 - 6.3e-08 32.4 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP63707.1 - 1.3e-06 28.0 0.0 2.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP63707.1 - 0.015 14.2 0.0 0.057 12.3 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 OAP63707.1 - 0.026 13.4 0.0 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 OAP63707.1 - 0.053 12.4 0.1 0.16 10.8 0.1 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain AAA PF00004.24 OAP63708.1 - 3e-53 179.5 0.0 2.8e-43 147.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAP63708.1 - 2.4e-05 25.1 0.0 0.0014 19.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAP63708.1 - 0.00023 21.1 1.0 0.02 14.8 0.0 3.8 4 1 1 5 5 4 1 AAA ATPase domain RuvB_N PF05496.7 OAP63708.1 - 0.00028 19.9 0.0 0.00065 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 OAP63708.1 - 0.00029 20.9 0.3 0.0091 16.1 0.0 3.2 3 1 1 4 4 3 1 AAA domain RNA_helicase PF00910.17 OAP63708.1 - 0.00031 20.9 0.0 0.015 15.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 OAP63708.1 - 0.00033 20.1 0.1 0.0024 17.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAP63708.1 - 0.00066 19.1 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Parvo_NS1 PF01057.12 OAP63708.1 - 0.0011 17.9 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.9 OAP63708.1 - 0.0021 17.9 0.0 0.0073 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 OAP63708.1 - 0.0065 16.1 0.0 0.025 14.3 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 OAP63708.1 - 0.0069 15.1 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 OAP63708.1 - 0.0076 15.9 0.0 0.08 12.6 0.0 2.6 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 OAP63708.1 - 0.0076 16.1 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 OAP63708.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.16 OAP63708.1 - 0.023 13.8 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 OAP63708.1 - 0.035 13.3 0.0 0.097 11.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 OAP63708.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAP63708.1 - 0.072 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAP63708.1 - 0.084 12.7 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 OAP63708.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 OAP63708.1 - 0.41 9.1 0.0 0.65 8.5 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase K_oxygenase PF13434.1 OAP63709.1 - 2.4e-111 371.9 0.0 2.8e-111 371.7 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP63709.1 - 5.7e-10 39.1 0.0 6.7e-07 29.2 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAP63709.1 - 3.1e-09 37.2 0.0 3.3e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP63709.1 - 0.00092 19.1 0.0 0.047 13.5 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 OAP63709.1 - 0.15 11.1 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) AMP-binding PF00501.23 OAP63710.1 - 1.4e-229 761.5 0.0 2.8e-77 259.8 0.0 4.6 4 1 0 4 4 4 3 AMP-binding enzyme Condensation PF00668.15 OAP63710.1 - 2.8e-170 564.9 1.1 5.9e-30 104.1 1.5 9.0 6 3 2 8 8 8 8 Condensation domain PP-binding PF00550.20 OAP63710.1 - 4.3e-58 193.4 1.7 1.5e-09 37.9 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 OAP63710.1 - 6.9e-16 58.9 0.0 1.7e-06 28.8 0.0 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 OAP63712.1 - 3.6e-37 127.8 25.1 4.9e-37 127.4 17.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP63712.1 - 0.012 15.3 0.8 0.061 13.1 0.0 2.4 2 0 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.11 OAP63713.1 - 4.5e-21 74.9 31.4 4.5e-21 74.9 21.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP63713.1 - 4.8e-16 58.3 28.4 6.8e-16 57.8 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ELMO_CED12 PF04727.8 OAP63714.1 - 1.1e-46 158.4 0.0 1.7e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 OAP63715.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) SUI1 PF01253.17 OAP63716.1 - 2.1e-23 81.9 0.2 4.7e-23 80.7 0.1 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 TnpV PF14198.1 OAP63716.1 - 0.00083 19.2 0.7 0.0013 18.6 0.5 1.3 1 0 0 1 1 1 1 Transposon-encoded protein TnpV tRNA_edit PF04073.10 OAP63716.1 - 0.041 13.7 1.7 0.064 13.1 1.2 1.3 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain Arfaptin PF06456.8 OAP63716.1 - 0.042 13.1 2.1 0.73 9.1 0.0 2.0 1 1 1 2 2 2 0 Arfaptin-like domain tRNA-synt_1g PF09334.6 OAP63716.1 - 0.095 11.3 0.1 1.3 7.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (M) HrpA_pilin PF09589.5 OAP63716.1 - 0.096 13.1 1.3 0.15 12.4 0.9 1.3 1 0 0 1 1 1 0 HrpA pilus formation protein Jnk-SapK_ap_N PF09744.4 OAP63716.1 - 0.4 10.6 4.4 0.58 10.1 3.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1752 PF08550.5 OAP63717.1 - 1.9e-07 30.5 1.0 3.5e-07 29.6 0.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GPI-anchored PF10342.4 OAP63718.1 - 5.6e-14 52.3 0.2 5.6e-14 52.3 0.1 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.4 OAP63718.1 - 0.051 11.8 12.5 0.055 11.7 8.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2076 PF09849.4 OAP63718.1 - 0.07 13.1 3.8 0.076 13.0 2.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF605 PF04652.11 OAP63718.1 - 0.75 9.1 9.5 0.79 9.0 6.6 1.1 1 0 0 1 1 1 0 Vta1 like DHHW PF14286.1 OAP63718.1 - 1.7 7.9 5.6 2 7.6 3.9 1.1 1 0 0 1 1 1 0 DHHW protein DNA_pol_viral_N PF00242.12 OAP63718.1 - 7.8 5.4 12.0 9.5 5.1 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain BNR PF02012.15 OAP63720.1 - 1.9e-12 44.9 36.0 0.13 12.1 0.1 10.8 11 0 0 11 11 11 7 BNR/Asp-box repeat PSII_BNR PF14870.1 OAP63720.1 - 1.5e-08 33.9 0.2 0.067 12.1 0.0 5.3 4 2 0 5 5 5 2 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.1 OAP63720.1 - 5.4e-07 29.1 8.5 1.6 7.9 0.1 6.9 4 2 0 5 5 5 3 BNR repeat-like domain CHB_HEX_C_1 PF13290.1 OAP63720.1 - 0.015 15.0 0.8 0.29 10.9 0.0 2.8 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF2167 PF09935.4 OAP63720.1 - 0.061 12.1 0.2 3.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) CsbD PF05532.7 OAP63721.1 - 0.00064 19.3 1.3 0.00093 18.8 0.9 1.2 1 0 0 1 1 1 1 CsbD-like PqqD PF05402.7 OAP63721.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DUF4061 PF13270.1 OAP63722.1 - 0.0079 16.2 3.1 0.014 15.4 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4061) Codanin-1_C PF15296.1 OAP63722.1 - 0.09 12.6 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Codanin-1 C-terminus GST_N_2 PF13409.1 OAP63722.1 - 0.23 11.4 1.7 3.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain Abhydrolase_3 PF07859.8 OAP63723.1 - 3.9e-13 49.4 0.1 5.5e-10 39.1 0.0 3.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 OAP63723.1 - 0.21 10.2 0.0 0.35 9.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) NUFIP1 PF10453.4 OAP63724.1 - 1e-09 37.7 9.2 1e-09 37.7 6.4 2.5 1 1 1 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 OAP63724.1 - 0.0001 21.8 1.2 0.00017 21.1 0.8 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Adenosine_kin PF04008.9 OAP63725.1 - 8.8e-72 239.6 0.0 1.1e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine specific kinase RNA_pol_Rbc25 PF08292.7 OAP63726.1 - 9.3e-35 119.4 0.0 1.5e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 OAP63726.1 - 1.8e-15 56.7 0.0 4.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 OAP63726.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 S1 RNA binding domain SeleniumBinding PF11524.3 OAP63726.1 - 0.086 12.9 0.0 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 Selenium binding protein Cys_Met_Meta_PP PF01053.15 OAP63727.1 - 2.5e-139 463.8 0.0 2.8e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAP63727.1 - 7.1e-09 35.0 0.1 1.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAP63727.1 - 6.2e-07 28.4 0.2 1.4e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 OAP63727.1 - 5.4e-06 25.6 0.2 9.4e-06 24.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 OAP63727.1 - 0.0031 16.7 0.1 0.0064 15.6 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DUF607 PF04678.8 OAP63728.1 - 0.012 15.5 3.5 0.06 13.2 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 EMP24_GP25L PF01105.19 OAP63728.1 - 0.016 14.9 2.9 0.017 14.8 0.2 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD AAA_13 PF13166.1 OAP63728.1 - 0.065 11.6 0.9 0.082 11.3 0.6 1.1 1 0 0 1 1 1 0 AAA domain Synaptobrevin PF00957.16 OAP63728.1 - 0.13 11.9 0.4 0.39 10.3 0.3 1.8 1 0 0 1 1 1 0 Synaptobrevin VIT1 PF01988.14 OAP63728.1 - 0.47 9.9 1.8 0.59 9.5 0.4 1.8 1 1 1 2 2 2 0 VIT family DUF2077 PF09850.4 OAP63728.1 - 0.54 9.6 3.6 0.23 10.8 0.4 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF2203 PF09969.4 OAP63728.1 - 2.2 8.4 5.6 5.6 7.1 0.1 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Tubulin PF00091.20 OAP63729.1 - 1.3e-66 224.4 0.0 1.8e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAP63729.1 - 5.5e-44 149.2 0.0 8.7e-44 148.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 OAP63729.1 - 0.00069 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.13 OAP63730.1 - 4.7e-23 81.6 0.9 7.3e-23 80.9 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 OAP63730.1 - 0.00011 21.1 0.3 0.00036 19.6 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 OAP63730.1 - 0.00025 20.2 0.0 0.00062 18.9 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 OAP63730.1 - 0.00028 20.4 0.1 0.0035 17.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 OAP63730.1 - 0.0003 20.8 0.3 0.0011 19.1 0.2 1.9 1 1 0 1 1 1 1 EF-hand domain pair Phage_1_1 PF08200.6 OAP63730.1 - 0.023 14.9 1.4 0.059 13.5 0.9 1.7 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein EF-hand_8 PF13833.1 OAP63730.1 - 0.29 10.7 1.8 0.63 9.6 1.2 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF2244 PF10003.4 OAP63730.1 - 8.4 5.7 9.3 2.5 7.4 1.9 2.5 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) adh_short PF00106.20 OAP63731.1 - 7.9e-23 81.1 2.6 1.1e-22 80.7 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP63731.1 - 3e-10 40.0 0.2 4.4e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP63731.1 - 9.1e-10 38.3 0.2 1.2e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP63731.1 - 2.7e-07 29.7 1.0 3.4e-07 29.4 0.7 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 OAP63731.1 - 5.3e-06 26.3 1.4 7.7e-06 25.8 1.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 OAP63731.1 - 0.00017 21.7 0.1 0.00032 20.7 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAP63731.1 - 0.00025 20.2 0.1 0.067 12.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 OAP63731.1 - 0.00093 19.5 0.8 0.0022 18.4 0.6 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_WecB PF03808.8 OAP63731.1 - 0.001 18.4 0.1 0.0038 16.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family SBP_bac_1 PF01547.20 OAP63731.1 - 0.0024 17.6 0.5 0.011 15.4 0.1 2.0 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein ApbA PF02558.11 OAP63731.1 - 0.0032 16.9 0.1 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_3 PF03447.11 OAP63731.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAP63731.1 - 0.036 13.7 0.3 0.068 12.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 OAP63731.1 - 0.039 12.8 0.2 0.071 11.9 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 OAP63731.1 - 0.058 13.3 0.6 0.14 12.0 0.4 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 OAP63731.1 - 0.086 12.8 3.1 0.47 10.4 2.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 OAP63731.1 - 0.12 11.0 0.3 0.48 9.0 0.2 1.9 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family ThiF PF00899.16 OAP63731.1 - 1.1 9.0 5.4 1.1 9.1 1.6 2.0 1 1 1 2 2 2 0 ThiF family PRC PF05239.11 OAP63732.1 - 0.015 15.1 1.1 0.41 10.5 0.0 2.8 3 0 0 3 3 3 0 PRC-barrel domain Myosin_head PF00063.16 OAP63733.1 - 3.4e-230 765.7 3.2 5.3e-230 765.1 2.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 OAP63733.1 - 4.1e-40 137.2 0.0 7.1e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 OAP63733.1 - 8.2e-13 47.5 0.1 1.9e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAP63733.1 - 4.2e-12 45.4 0.0 1.2e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAP63733.1 - 3.3e-11 42.4 0.0 9.9e-11 40.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 OAP63733.1 - 0.0042 17.2 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 OAP63733.1 - 0.011 15.1 0.4 1.6 8.0 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IQ PF00612.22 OAP63733.1 - 0.017 14.7 8.1 0.9 9.3 0.9 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_17 PF13207.1 OAP63733.1 - 0.021 15.6 0.0 0.063 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 OAP63733.1 - 0.036 13.1 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 OAP63733.1 - 0.078 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAP63733.1 - 0.12 12.0 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain HNH_2 PF13391.1 OAP63734.1 - 6.6e-17 61.0 0.0 1.2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Mst1_SARAH PF11629.3 OAP63735.1 - 0.026 14.3 0.1 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 OPA3 PF07047.7 OAP63736.1 - 2e-31 108.4 2.5 2e-31 108.4 1.7 2.4 2 1 0 2 2 2 1 Optic atrophy 3 protein (OPA3) SieB PF14163.1 OAP63736.1 - 0.01 15.3 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Superinfection exclusion protein B Pkinase PF00069.20 OAP63737.1 - 1.2e-71 240.9 0.1 1.7e-71 240.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63737.1 - 1.1e-44 152.4 0.2 1.7e-44 151.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP63737.1 - 2.5e-08 33.2 0.0 1e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like POLO_box PF00659.13 OAP63737.1 - 6.6e-06 25.9 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 OAP63737.1 - 0.046 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-Hacid_dh_C PF02826.14 OAP63738.1 - 2.2e-33 114.8 0.5 1.2e-20 73.4 0.0 3.7 3 1 0 3 3 3 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 OAP63739.1 - 1.5e-08 34.2 0.1 0.00033 20.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.9 OAP63739.1 - 0.00028 20.5 3.7 0.0054 16.3 0.2 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase DHDPS PF00701.17 OAP63740.1 - 3.2e-37 127.7 0.0 3.7e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-DHHC PF01529.15 OAP63741.1 - 2.6e-11 43.2 2.7 3.7e-11 42.7 1.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DNA_mis_repair PF01119.14 OAP63742.1 - 2.6e-14 52.7 0.0 6e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 OAP63742.1 - 2.2e-11 43.4 0.2 4.9e-11 42.3 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAP63742.1 - 2.8e-10 39.9 0.1 6e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ACT_7 PF13840.1 OAP63743.1 - 1e-10 40.9 0.0 1.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT_3 PF10000.4 OAP63743.1 - 7.2e-10 38.4 0.1 1.6e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 ACT domain Pkinase PF00069.20 OAP63746.1 - 8.3e-30 103.7 0.0 1.8e-28 99.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63746.1 - 4.8e-20 71.7 0.0 7.5e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP63746.1 - 0.0017 17.3 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAP63746.1 - 0.029 14.0 0.1 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Patatin PF01734.17 OAP63747.1 - 2.9e-05 24.0 0.0 4.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase ApoLp-III PF07464.6 OAP63747.1 - 0.078 12.9 0.4 0.23 11.4 0.2 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) IncA PF04156.9 OAP63747.1 - 0.19 11.2 4.9 0.29 10.6 0.4 2.4 2 1 0 2 2 2 0 IncA protein HeLo PF14479.1 OAP63748.1 - 5e-19 68.9 0.0 8.4e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 OAP63748.1 - 0.032 13.3 0.0 0.14 11.2 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 OAP63748.1 - 0.084 12.0 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Transp_cyt_pur PF02133.10 OAP63750.1 - 1.6e-103 346.6 44.3 1.9e-103 346.4 30.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CcmD PF04995.9 OAP63750.1 - 0.12 12.0 0.1 0.12 12.0 0.1 4.2 3 1 1 4 4 4 0 Heme exporter protein D (CcmD) DUF917 PF06032.7 OAP63751.1 - 5.3e-110 367.2 0.0 1.2e-109 366.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 OAP63751.1 - 8.3e-48 162.9 10.1 6.9e-47 159.9 2.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 OAP63751.1 - 2.3e-30 105.3 2.3 8.8e-27 93.7 0.0 3.9 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 OAP63751.1 - 3.2e-06 25.7 1.6 0.0091 14.3 0.0 2.3 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 OAP63751.1 - 0.0023 17.2 2.2 0.0029 16.9 0.0 2.2 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family PGM_PMM_I PF02878.11 OAP63751.1 - 0.006 16.0 0.1 0.059 12.8 0.0 2.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF3453 PF11935.3 OAP63752.1 - 2.6e-68 229.9 0.0 4.3e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DUF615 PF04751.9 OAP63752.1 - 0.0034 17.0 0.4 1.4 8.4 0.0 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF615) PhoU PF01895.14 OAP63752.1 - 0.25 11.8 1.6 37 4.8 0.1 3.5 3 0 0 3 3 3 0 PhoU domain MFS_1 PF07690.11 OAP63753.1 - 5e-40 137.3 46.3 5e-40 137.3 32.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP63753.1 - 4e-10 38.5 13.7 7.1e-10 37.7 9.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RSF PF14876.1 OAP63754.1 - 0.032 13.0 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Thiolase_N PF00108.18 OAP63755.1 - 1.5e-70 237.2 0.0 2e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAP63755.1 - 2.3e-39 133.5 0.0 4.2e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 OAP63755.1 - 0.0041 16.7 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PS_Dcarbxylase PF02666.10 OAP63756.1 - 2e-49 167.6 0.0 2.7e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase WD40 PF00400.27 OAP63757.1 - 2e-45 151.0 16.4 3.3e-11 42.6 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 OAP63757.1 - 2.4e-14 52.2 3.4 2.4e-14 52.2 2.3 2.3 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 OAP63757.1 - 0.038 13.1 0.0 9.7 5.2 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Fungal_trans PF04082.13 OAP63758.1 - 1.2e-07 30.8 0.1 2.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63758.1 - 0.00016 21.5 7.8 0.00041 20.2 5.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1772 PF08592.6 OAP63760.1 - 3.4e-09 36.5 0.5 5.6e-09 35.8 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF308 PF03729.8 OAP63760.1 - 0.1 12.5 1.9 6.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Cm_res_leader PF08077.6 OAP63760.1 - 6 6.7 5.4 21 5.1 0.0 2.7 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide MFS_1 PF07690.11 OAP63761.1 - 6.1e-16 58.0 52.5 9e-11 41.0 11.0 3.3 1 1 0 3 3 3 3 Major Facilitator Superfamily EXS PF03124.9 OAP63761.1 - 0.0037 16.3 1.8 0.0077 15.2 1.2 1.5 1 0 0 1 1 1 1 EXS family PLAC8 PF04749.12 OAP63761.1 - 8.2 7.0 7.9 1.7 9.2 1.5 3.0 3 1 0 3 3 3 0 PLAC8 family Peptidase_S9 PF00326.16 OAP63762.1 - 1.1e-53 181.6 2.6 2.1e-53 180.6 1.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP63762.1 - 1.2e-07 31.6 0.2 2.2e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 OAP63762.1 - 0.0043 16.6 1.8 0.13 11.9 0.1 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF218 PF02698.12 OAP63763.1 - 4.6e-11 42.4 0.0 6.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Sugar_tr PF00083.19 OAP63765.1 - 4.1e-81 272.8 29.6 4.8e-81 272.6 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63765.1 - 1.2e-27 96.6 37.7 4.4e-16 58.5 12.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily IRK PF01007.15 OAP63765.1 - 0.18 10.5 1.2 0.38 9.4 0.8 1.5 1 0 0 1 1 1 0 Inward rectifier potassium channel Fungal_trans PF04082.13 OAP63766.1 - 4.5e-31 107.6 1.0 7e-31 107.0 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63766.1 - 1.5e-07 31.2 8.7 2.8e-07 30.3 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_3 PF01757.17 OAP63767.1 - 1.7e-19 69.8 29.1 2.2e-19 69.4 20.2 1.2 1 0 0 1 1 1 1 Acyltransferase family Phospho_p8 PF10195.4 OAP63768.1 - 0.068 13.0 0.5 0.21 11.5 0.3 1.8 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 ubiquitin PF00240.18 OAP63769.1 - 9.8e-103 335.6 15.6 6.5e-34 115.1 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 OAP63769.1 - 1.8e-59 197.3 13.8 2.5e-19 68.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAP63769.1 - 6.1e-19 68.0 6.5 9e-05 22.6 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAP63769.1 - 7.6e-17 61.4 0.5 0.00041 20.0 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAP63769.1 - 6.7e-11 42.0 1.2 0.078 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAP63769.1 - 1.2e-10 41.4 0.7 0.076 13.2 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 OAP63769.1 - 5.1e-08 32.8 0.0 0.99 9.4 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 OAP63769.1 - 2e-05 24.3 2.6 2.8 7.9 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 OAP63769.1 - 0.00019 21.0 0.5 8.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) FlgD_ig PF13860.1 OAP63769.1 - 0.00044 19.9 2.4 9.2 6.0 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Methyltrans_RNA PF04452.9 OAP63769.1 - 0.00081 18.5 0.1 1.2 8.2 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Plexin_cytopl PF08337.7 OAP63769.1 - 0.00084 17.7 8.1 1.5 7.0 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 OAP63769.1 - 0.011 15.2 0.0 30 3.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.2 OAP63769.1 - 0.015 15.3 2.7 31 4.7 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_4 PF13291.1 OAP63769.1 - 0.02 15.2 0.4 68 3.9 0.0 3.2 3 0 0 3 3 3 0 ACT domain GABP-alpha PF11620.3 OAP63769.1 - 0.032 14.1 3.9 26 4.8 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain Tash_PEST PF07708.6 OAP63769.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif CTDII PF01556.13 OAP63769.1 - 0.052 13.4 9.2 5 7.0 0.2 3.4 1 1 2 3 3 3 0 DnaJ C terminal domain EMG1 PF03587.9 OAP63769.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase FERM_N PF09379.5 OAP63769.1 - 0.092 12.8 8.6 28 4.8 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 OAP63769.1 - 0.29 11.1 3.6 70 3.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 OAP63769.1 - 3.3 7.4 7.5 46 3.7 0.1 3.1 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 KID PF02524.9 OAP63769.1 - 6.8 7.2 8.1 2.1e+02 2.8 0.1 4.8 3 0 0 3 3 3 0 KID repeat Cu_amine_oxid PF01179.15 OAP63770.1 - 3.4e-05 22.7 1.5 0.091 11.4 0.0 3.7 2 1 1 3 3 3 2 Copper amine oxidase, enzyme domain Cupin_2 PF07883.6 OAP63771.1 - 6.2e-15 54.4 0.1 4.7e-08 32.4 0.0 2.7 2 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 OAP63771.1 - 2.7e-06 26.8 0.0 0.0066 15.8 0.0 2.2 2 0 0 2 2 2 2 Cupin MannoseP_isomer PF01050.13 OAP63771.1 - 7.1e-05 22.4 0.0 0.00068 19.2 0.0 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.7 OAP63771.1 - 0.015 14.7 0.0 1.4 8.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF861) FdtA PF05523.6 OAP63771.1 - 0.064 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 WxcM-like, C-terminal Auxin_BP PF02041.11 OAP63771.1 - 0.084 12.3 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Auxin binding protein TPR_10 PF13374.1 OAP63772.1 - 3.3e-96 312.8 7.0 7.5e-12 44.7 0.0 11.0 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 OAP63772.1 - 1e-74 246.4 14.1 1.7e-15 56.6 0.1 7.2 5 1 2 8 8 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 OAP63772.1 - 1.8e-23 80.4 19.6 0.017 14.8 0.0 9.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 OAP63772.1 - 7.7e-23 79.9 2.4 8.2e-05 22.1 0.0 6.8 4 1 3 7 7 7 6 TPR repeat TPR_2 PF07719.12 OAP63772.1 - 3.3e-21 73.4 8.8 0.013 15.4 0.0 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 OAP63772.1 - 1.2e-20 73.6 8.1 0.00047 20.7 0.0 8.2 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAP63772.1 - 1.2e-19 68.9 3.9 0.094 12.3 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_4 PF07721.9 OAP63772.1 - 1.7e-16 58.9 11.8 0.023 15.0 0.0 10.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAP63772.1 - 3.6e-14 52.8 12.6 0.0033 17.7 0.3 8.7 2 2 9 11 11 11 5 Tetratricopeptide repeat Apc3 PF12895.2 OAP63772.1 - 9.8e-14 51.2 0.7 0.0018 18.3 0.0 6.9 1 1 8 9 9 9 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 OAP63772.1 - 4.3e-13 48.3 0.7 2.4 8.5 0.0 9.2 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP63772.1 - 3e-12 46.0 20.3 0.12 13.0 0.1 10.5 5 2 6 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAP63772.1 - 1.2e-09 37.2 2.1 18 5.3 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 OAP63772.1 - 6.5e-06 25.2 0.8 0.00014 20.9 0.6 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_6 PF13174.1 OAP63772.1 - 1.1e-05 25.5 17.1 5.1 7.7 0.0 9.1 9 0 0 9 9 8 1 Tetratricopeptide repeat NB-ARC PF00931.17 OAP63772.1 - 6.4e-05 21.9 0.0 0.00036 19.4 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.1 OAP63772.1 - 0.013 14.9 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAP63772.1 - 0.016 15.3 0.0 0.32 11.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain Fis1_TPR_C PF14853.1 OAP63772.1 - 0.041 13.7 0.3 54 3.7 0.0 4.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 OAP63772.1 - 0.065 13.0 0.2 27 4.6 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAP63772.1 - 0.12 12.5 12.0 23 5.1 0.1 6.7 6 2 4 10 10 8 0 Tetratricopeptide repeat PPR_3 PF13812.1 OAP63772.1 - 0.15 12.4 2.6 1e+02 3.5 0.0 5.1 6 0 0 6 6 3 0 Pentatricopeptide repeat domain BRAP2 PF07576.7 OAP63773.1 - 2.1e-24 85.2 0.0 4.6e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 OAP63773.1 - 3.1e-19 68.8 3.7 8.2e-19 67.4 2.6 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 OAP63773.1 - 1.3e-10 40.9 9.5 1.3e-10 40.9 6.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 OAP63773.1 - 1.6e-05 24.4 7.2 4.1e-05 23.1 5.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP63773.1 - 3.3e-05 23.4 5.2 3.3e-05 23.4 3.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP63773.1 - 3.8e-05 23.3 6.5 3.8e-05 23.3 4.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAP63773.1 - 0.0001 22.2 8.7 0.0001 22.2 6.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAP63773.1 - 0.00025 20.7 4.2 0.00045 19.8 1.4 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 OAP63773.1 - 0.0023 17.9 4.4 0.0023 17.9 3.1 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger DUF892 PF05974.7 OAP63773.1 - 0.0067 16.2 8.3 0.0067 16.2 5.8 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF892) zf-Apc11 PF12861.2 OAP63773.1 - 0.0079 16.0 5.0 0.018 14.8 3.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 OAP63773.1 - 0.027 14.2 4.2 0.086 12.6 2.9 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 OAP63773.1 - 0.19 11.3 6.1 0.4 10.2 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1759 PF03564.10 OAP63773.1 - 0.21 11.3 5.3 0.39 10.5 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) AAA_23 PF13476.1 OAP63773.1 - 1.1 9.4 7.2 2.2 8.5 5.0 1.5 1 0 0 1 1 1 0 AAA domain Baculo_RING PF05883.6 OAP63773.1 - 2 8.2 6.9 0.45 10.3 0.6 2.4 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Imm6 PF14434.1 OAP63773.1 - 2.1 8.0 6.0 0.39 10.4 0.8 2.2 3 0 0 3 3 3 0 Immunity protein Imm6 Exonuc_VII_L PF02601.10 OAP63773.1 - 7.6 5.6 14.9 14 4.7 10.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Transp_cyt_pur PF02133.10 OAP63774.1 - 8.1e-94 314.6 36.3 9.3e-94 314.4 25.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 OAP63775.1 - 2.7e-25 89.1 0.0 4.6e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP63775.1 - 1.6e-14 53.9 0.0 1.4e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 OAP63776.1 - 1.2e-23 83.3 2.0 1.8e-23 82.7 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.1 OAP63777.1 - 7.2e-19 68.0 0.0 1.4e-18 67.0 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP63777.1 - 4.8e-15 55.8 0.0 8.2e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP63777.1 - 1.1e-14 54.3 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP63777.1 - 2.1e-13 50.5 0.0 3.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP63777.1 - 2.2e-13 50.7 0.0 2e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP63777.1 - 2.8e-07 30.8 0.0 4.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAP63777.1 - 7e-06 25.3 0.0 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 OAP63777.1 - 1.6e-05 24.8 0.0 7.1e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP63777.1 - 3.5e-05 23.2 0.0 8e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 OAP63777.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.11 OAP63777.1 - 0.19 10.0 0.0 0.28 9.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Fungal_trans PF04082.13 OAP63778.1 - 3.5e-19 68.6 0.1 5.6e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 OAP63779.1 - 2.4e-09 37.3 0.0 8.7e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP63779.1 - 0.00071 19.4 0.0 0.0011 18.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.11 OAP63780.1 - 2.8e-34 118.3 34.9 4.1e-34 117.8 24.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 OAP63781.1 - 2.1e-05 24.3 6.8 3.6e-05 23.5 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3HCDH_N PF02737.13 OAP63782.1 - 1.8e-28 99.3 0.0 2.6e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 OAP63782.1 - 3.4e-23 81.8 0.0 6.8e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.11 OAP63782.1 - 0.012 15.0 0.0 0.033 13.6 0.0 1.8 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 OAP63782.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 OAP63782.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 OAP63782.1 - 0.097 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase E1-E2_ATPase PF00122.15 OAP63783.1 - 1.9e-65 220.1 2.5 3.3e-65 219.3 1.7 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAP63783.1 - 6.2e-36 123.6 0.9 6.2e-36 123.6 0.6 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAP63783.1 - 6.2e-28 98.6 0.3 5.3e-23 82.5 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAP63783.1 - 6.8e-20 70.8 0.0 1.8e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAP63783.1 - 2.6e-15 55.6 0.0 7.5e-15 54.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 OAP63783.1 - 2.2e-11 44.2 0.1 6.9e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAP63783.1 - 9.9e-05 22.0 1.2 0.0039 16.7 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cullin PF00888.17 OAP63784.1 - 0.028 12.9 2.4 0.057 11.9 1.6 1.5 1 1 0 1 1 1 0 Cullin family DUF155 PF02582.9 OAP63784.1 - 0.075 12.9 0.4 0.3 10.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 DUF2935 PF11155.3 OAP63784.1 - 0.079 13.0 4.1 0.88 9.6 0.2 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.5 OAP63784.1 - 0.68 10.0 3.5 1.5 8.9 0.4 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Vps51 PF08700.6 OAP63784.1 - 0.82 9.5 8.0 16 5.3 0.3 3.7 3 1 0 3 3 3 0 Vps51/Vps67 Zwint PF15556.1 OAP63784.1 - 1 8.5 14.9 1.4 8.0 0.8 2.8 2 1 0 2 2 2 0 ZW10 interactor Allexi_40kDa PF05549.6 OAP63784.1 - 1.7 7.8 8.9 3.1 7.0 0.1 3.1 2 1 1 3 3 3 0 Allexivirus 40kDa protein STAT_alpha PF01017.15 OAP63784.1 - 2.3 7.8 8.4 0.16 11.6 1.2 2.5 3 0 0 3 3 3 0 STAT protein, all-alpha domain DUF962 PF06127.6 OAP63785.1 - 3.9e-26 90.7 0.0 7.3e-26 89.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) MIG-14_Wnt-bd PF06664.7 OAP63785.1 - 0.22 10.3 2.8 0.98 8.1 0.1 2.0 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Cytochrom_B561 PF03188.11 OAP63786.1 - 1.3e-13 50.9 3.3 1.3e-13 50.9 2.3 2.5 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 OAP63786.1 - 0.0036 16.8 2.3 0.0036 16.8 1.6 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF2427) PepSY_TM_3 PF13706.1 OAP63786.1 - 0.05 13.0 0.1 7.5 6.0 0.0 3.1 2 0 0 2 2 2 0 PepSY-associated TM helix Cytochrom_B_N PF00033.14 OAP63786.1 - 0.91 8.8 17.0 1.5 8.1 8.6 2.8 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF418 PF04235.7 OAP63786.1 - 9.3 5.8 15.9 37 3.9 9.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF418) PNTB PF02233.11 OAP63787.1 - 3.5e-170 566.7 23.3 3.5e-170 566.7 16.2 1.4 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 OAP63787.1 - 1.1e-52 177.9 0.9 2.1e-52 177.0 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 OAP63787.1 - 1.2e-44 151.6 0.0 2.3e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 OAP63787.1 - 3.2e-29 100.9 2.9 3.2e-29 100.9 2.0 5.2 4 2 2 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 OAP63787.1 - 0.00016 20.8 0.1 1.2 8.2 0.0 3.4 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 OAP63787.1 - 0.003 17.1 0.0 0.0076 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 OAP63787.1 - 0.0086 15.6 0.1 0.037 13.5 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 OAP63787.1 - 0.012 15.4 0.1 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.17 OAP63787.1 - 0.044 13.5 1.0 0.24 11.1 0.4 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_3 PF13738.1 OAP63787.1 - 0.055 13.5 0.2 10 6.0 0.4 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAP63787.1 - 0.081 13.0 3.7 3.8 7.6 0.0 3.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 OAP63787.1 - 0.14 12.7 0.0 0.43 11.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 OAP63787.1 - 0.26 11.3 3.0 1 9.4 0.8 3.1 2 2 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Acetyltransf_3 PF13302.1 OAP63788.1 - 1.2e-19 70.8 0.0 2e-19 70.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP63788.1 - 3.2e-08 33.4 0.0 5.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 OAP63788.1 - 0.00028 20.8 0.0 0.00065 19.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAP63788.1 - 0.0021 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.14 OAP63790.1 - 2.9e-37 128.5 0.0 1.8e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DDE_3 PF13358.1 OAP63791.1 - 1.8e-13 50.5 0.9 3.3e-13 49.6 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Fungal_trans PF04082.13 OAP63792.1 - 3.4e-13 49.0 0.3 5e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.17 OAP63793.1 - 2.1e-51 174.8 0.0 2.4e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Aa_trans PF01490.13 OAP63794.1 - 4.3e-27 94.6 26.7 4.9e-27 94.4 18.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1129 PF06570.6 OAP63794.1 - 0.72 9.1 6.2 1.8 7.8 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) CBS PF00571.23 OAP63795.1 - 2.1e-06 27.4 0.0 0.023 14.4 0.0 2.9 3 0 0 3 3 3 2 CBS domain Mito_carr PF00153.22 OAP63796.1 - 1.6e-46 155.9 9.7 6e-18 64.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3602 PF12223.3 OAP63796.1 - 2.7e-11 43.6 9.8 7.7e-09 35.8 2.3 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) DUF3484 PF11983.3 OAP63796.1 - 0.14 13.0 1.1 1.3 9.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3484) BAH PF01426.13 OAP63797.1 - 1.4e-05 24.8 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 OAP63797.1 - 0.0047 16.5 2.7 0.01 15.4 1.8 1.5 1 0 0 1 1 1 1 PHD-finger MFS_1 PF07690.11 OAP63798.1 - 2.3e-51 174.5 48.1 4.6e-49 167.0 34.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP63798.1 - 1e-17 63.6 21.0 2.1e-17 62.5 14.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAP63798.1 - 2.3e-12 46.2 11.3 2.3e-12 46.2 7.8 4.4 2 1 2 4 4 4 2 Sugar (and other) transporter zf-CCCH PF00642.19 OAP63799.1 - 1.4e-21 75.6 34.8 2.7e-07 30.1 0.5 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 OAP63799.1 - 0.00028 20.7 40.1 0.021 14.7 0.0 6.0 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_60s PF00428.14 OAP63799.1 - 0.05 14.0 1.8 0.082 13.3 1.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Toxin_34 PF08396.5 OAP63799.1 - 0.66 10.5 13.2 0.72 10.4 6.2 2.7 2 1 0 2 2 2 0 Spider toxin omega agatoxin/Tx1 family LRV_FeS PF05484.6 OAP63799.1 - 2.5 7.7 21.3 3.8 7.1 0.3 4.9 3 2 3 6 6 6 0 LRV protein FeS4 cluster Esterase PF00756.15 OAP63800.1 - 7.7e-50 169.6 0.0 1.1e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAP63800.1 - 3.3e-06 26.9 0.0 5.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 OAP63800.1 - 6.8e-06 25.4 0.0 0.00058 19.1 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 OAP63800.1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP63800.1 - 0.00028 20.3 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 OAP63800.1 - 0.0004 19.6 0.0 0.00091 18.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 OAP63800.1 - 0.0092 14.8 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.8 OAP63800.1 - 0.011 14.0 0.0 0.019 13.3 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 OAP63800.1 - 0.021 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 OAP63800.1 - 0.04 13.4 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 OAP63800.1 - 0.044 13.0 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AXE1 PF05448.7 OAP63800.1 - 0.048 12.1 0.0 0.11 10.9 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF1772 PF08592.6 OAP63800.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) MFS_1 PF07690.11 OAP63801.1 - 1e-32 113.2 30.6 1e-32 113.2 21.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP63801.1 - 5.9e-06 24.7 3.4 5.9e-06 24.7 2.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAP63801.1 - 1.7e-05 23.6 29.8 0.00012 20.7 20.7 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1049 PF06305.6 OAP63801.1 - 0.11 12.0 16.4 3.1 7.3 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) GP41 PF00517.12 OAP63801.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral envelope protein Alpha_E2_glycop PF00943.14 OAP63801.1 - 0.21 10.1 0.3 0.32 9.5 0.2 1.2 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Xpo1 PF08389.7 OAP63802.1 - 3e-37 127.8 0.8 2.3e-36 124.9 0.0 2.9 3 1 1 4 4 4 1 Exportin 1-like protein Ribosomal_L29e PF01779.12 OAP63803.1 - 9.8e-15 54.1 12.1 2.7e-07 30.3 0.3 2.4 2 0 0 2 2 2 2 Ribosomal L29e protein family CD34_antigen PF06365.7 OAP63803.1 - 0.079 12.6 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2749 PF10907.3 OAP63803.1 - 0.26 11.2 1.1 0.68 9.8 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) 7tm_2 PF00002.19 OAP63804.1 - 7.3e-06 25.2 10.2 1.3e-05 24.3 7.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 OAP63804.1 - 0.00025 20.0 2.6 0.00025 20.0 1.8 2.1 1 1 0 2 2 2 1 Slime mold cyclic AMP receptor DUF2277 PF10041.4 OAP63804.1 - 0.093 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) Pox_A14 PF05767.7 OAP63804.1 - 1.5 8.7 7.2 0.39 10.7 0.2 3.1 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Internalin_N PF12354.3 OAP63804.1 - 1.7 8.2 7.3 0.12 12.0 0.3 2.7 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal Sybindin PF04099.7 OAP63805.1 - 8.7e-25 87.0 0.0 1.2e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 OAP63805.1 - 0.0048 16.7 0.0 0.0067 16.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 OAP63806.1 - 1.6e-56 191.3 0.0 2.5e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63806.1 - 2.9e-34 118.3 0.3 2.9e-32 111.7 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 OAP63806.1 - 1.8e-09 36.9 0.0 2.1e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAP63806.1 - 0.0093 15.7 0.0 0.0093 15.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family SRI PF08236.6 OAP63807.1 - 1.5e-21 76.1 11.5 1.5e-21 76.1 8.0 2.5 1 1 1 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 OAP63807.1 - 1.2e-20 74.4 0.3 1.2e-20 74.4 0.2 3.9 3 2 0 3 3 3 1 SET domain Med26 PF08711.6 OAP63807.1 - 9.1e-05 21.8 2.1 0.00028 20.3 0.2 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.21 OAP63807.1 - 0.019 14.8 1.2 0.045 13.6 0.9 1.7 1 0 0 1 1 1 0 WW domain eIF-6 PF01912.13 OAP63808.1 - 4.7e-83 277.1 0.7 6.2e-83 276.7 0.5 1.1 1 0 0 1 1 1 1 eIF-6 family Thaumatin PF00314.12 OAP63809.1 - 0.12 11.8 5.9 2 7.7 0.0 2.9 2 1 1 3 3 3 0 Thaumatin family Lipase_3 PF01764.20 OAP63810.1 - 1.9e-17 63.2 0.0 5.4e-16 58.4 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAP63810.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family TAP_C PF03943.8 OAP63811.1 - 8.9e-11 41.0 0.2 1.7e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 OAP63811.1 - 3.6e-08 32.8 2.8 6.9e-05 22.3 0.1 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 OAP63811.1 - 0.00093 18.9 2.7 2.6 8.4 0.1 3.8 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.1 OAP63811.1 - 0.0021 17.7 0.9 0.0049 16.5 0.6 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.1 OAP63811.1 - 0.024 14.6 0.9 11 6.5 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat DUF3849 PF12960.2 OAP63811.1 - 0.043 13.7 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) LRR_7 PF13504.1 OAP63811.1 - 0.047 13.8 1.8 1.7 9.1 0.1 3.6 3 0 0 3 3 3 0 Leucine rich repeat Vps53_N PF04100.7 OAP63812.1 - 1.8e-103 346.2 7.5 2.6e-103 345.7 5.2 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 OAP63812.1 - 2.3e-05 23.4 11.1 4e-05 22.6 7.7 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 OAP63812.1 - 0.0018 18.0 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sigma70_ner PF04546.8 OAP63812.1 - 0.0038 16.8 8.3 0.22 11.1 3.8 2.4 2 0 0 2 2 2 2 Sigma-70, non-essential region MutS_III PF05192.13 OAP63812.1 - 0.0098 15.6 0.2 0.083 12.6 0.1 2.8 1 1 0 1 1 1 1 MutS domain III HAP1_N PF04849.8 OAP63812.1 - 0.12 11.3 16.5 0.25 10.2 10.4 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF342 PF03961.8 OAP63812.1 - 0.13 10.7 4.3 0.2 10.0 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Zw10 PF06248.8 OAP63812.1 - 0.19 9.8 9.3 0.34 8.9 6.4 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 COG2 PF06148.6 OAP63812.1 - 0.29 11.0 10.8 0.025 14.4 3.8 2.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.14 OAP63812.1 - 0.66 7.7 4.4 0.98 7.1 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family adh_short PF00106.20 OAP63813.1 - 1.3e-17 64.1 1.5 1.8e-12 47.4 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAP63813.1 - 9.6e-06 25.3 2.2 3.1e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 OAP63813.1 - 0.074 12.4 0.3 0.2 11.0 0.0 1.8 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family COPIIcoated_ERV PF07970.7 OAP63814.1 - 1.8e-69 233.7 0.0 1.2e-45 155.8 0.0 2.3 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 OAP63814.1 - 4.1e-34 116.4 0.0 8.4e-34 115.4 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) HSP90 PF00183.13 OAP63815.1 - 2.6e-257 854.4 37.4 3.1e-257 854.2 25.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 OAP63815.1 - 5.4e-12 45.5 0.2 5.4e-12 45.5 0.1 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAP63815.1 - 1.2e-11 44.2 0.1 2.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 OAP63815.1 - 0.11 12.3 0.2 0.11 12.3 0.1 2.5 3 0 0 3 3 3 0 Tumour suppressor protein DUF1676 PF07898.8 OAP63815.1 - 4.2 7.7 9.4 0.43 10.9 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) HLH PF00010.21 OAP63816.1 - 2.9e-13 49.2 1.2 5.5e-13 48.3 0.0 2.1 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain TPR_11 PF13414.1 OAP63817.1 - 4.5e-07 29.4 7.8 0.02 14.5 0.3 5.0 3 2 2 5 5 5 2 TPR repeat Nro1 PF12753.2 OAP63817.1 - 0.0065 15.4 0.9 0.0065 15.4 0.6 2.1 2 1 0 2 2 2 1 Nuclear pore complex subunit Nro1 TPR_17 PF13431.1 OAP63817.1 - 0.025 14.7 2.2 7.1 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAP63817.1 - 0.22 11.8 0.1 0.22 11.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP63817.1 - 1.1 10.0 0.0 1.1 10.0 0.0 4.9 5 3 1 6 6 6 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 OAP63819.1 - 0.0037 17.4 19.6 0.041 14.2 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP63819.1 - 0.0094 16.2 2.4 0.0094 16.2 1.6 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAP63819.1 - 1.9 8.9 18.7 4.1 7.8 2.3 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 OAP63819.1 - 2.2 8.5 7.9 17 5.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Peptidase_M22 PF00814.20 OAP63820.1 - 8.6e-49 166.4 0.0 1.6e-47 162.2 0.0 2.6 1 1 0 1 1 1 1 Glycoprotease family Cornifin PF02389.10 OAP63821.1 - 0.014 15.1 7.3 0.015 15.0 5.1 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family AA_permease_2 PF13520.1 OAP63822.1 - 1.3e-50 172.2 47.9 1.6e-50 171.8 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP63822.1 - 5e-20 71.2 40.7 7.3e-20 70.7 28.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1254 PF06863.7 OAP63823.1 - 1.9e-27 95.5 2.9 3.2e-27 94.8 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.6 OAP63823.1 - 6e-16 58.7 2.7 6.8e-16 58.6 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) DUF1180 PF06679.7 OAP63823.1 - 0.05 13.4 3.8 0.069 13.0 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4449 PF14613.1 OAP63824.1 - 2.1e-06 27.7 2.6 3e-06 27.2 0.1 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) Malic_M PF03949.10 OAP63825.1 - 2.8e-86 289.2 0.0 4e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 OAP63825.1 - 1.9e-63 213.3 0.0 3e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Mob1_phocein PF03637.12 OAP63826.1 - 2.8e-71 238.7 0.0 3.8e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family MIP-T3 PF10243.4 OAP63827.1 - 9.5 4.5 28.2 0.48 8.8 12.7 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Methyltransf_2 PF00891.13 OAP63828.1 - 2.2e-24 85.9 0.0 3.7e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 OAP63829.1 - 4.9e-19 68.6 0.0 9e-19 67.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP63829.1 - 1.2e-09 37.9 0.0 3e-08 33.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP63829.1 - 2.1e-08 34.7 0.2 4.4e-07 30.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP63829.1 - 4.9e-08 33.3 0.0 9.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP63829.1 - 2.8e-06 27.7 0.0 1.9e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP63829.1 - 5.1e-05 23.5 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP63829.1 - 9.9e-05 22.3 0.1 0.0011 19.0 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAP63829.1 - 0.00045 19.4 0.0 0.0006 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 OAP63829.1 - 0.018 14.3 0.0 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.15 OAP63829.1 - 0.032 13.2 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 OAP63829.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ribosomal_L31 PF01197.13 OAP63830.1 - 0.039 13.9 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 Vps5 PF09325.5 OAP63831.1 - 8.4e-86 287.0 1.3 8.4e-86 287.0 0.9 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 OAP63831.1 - 1.5e-25 89.1 0.0 3.7e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 PX domain G6PD_bact PF10786.4 OAP63831.1 - 0.12 11.8 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DUF605 PF04652.11 OAP63832.1 - 0.46 9.8 13.8 0.54 9.5 9.6 1.1 1 0 0 1 1 1 0 Vta1 like Zip PF02535.17 OAP63833.1 - 0.6 9.0 3.4 1.2 8.0 2.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter ATP-synt_DE_N PF02823.11 OAP63834.1 - 3.7e-20 71.4 0.1 5.2e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HECT_2 PF09814.4 OAP63835.1 - 5.2e-60 203.0 0.0 2.1e-59 201.0 0.0 1.7 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PI-PLC-X PF00388.14 OAP63836.1 - 7.1e-58 194.1 0.0 1e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 OAP63836.1 - 3.8e-36 123.6 0.0 6.9e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Cob_adeno_trans PF01923.13 OAP63837.1 - 0.041 13.6 1.7 0.069 12.9 1.2 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Exonuc_VII_L PF02601.10 OAP63837.1 - 3.6 6.6 5.3 4.3 6.4 3.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CAP PF00188.21 OAP63839.1 - 8e-08 32.8 0.1 2.3e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Cupin_2 PF07883.6 OAP63840.1 - 0.011 15.2 1.3 0.014 14.8 0.9 1.2 1 0 0 1 1 1 0 Cupin domain FAD_binding_2 PF00890.19 OAP63841.1 - 4.9e-125 417.6 2.9 6.3e-125 417.2 2.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 OAP63841.1 - 5.7e-48 162.0 1.2 8.5e-48 161.4 0.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 OAP63841.1 - 2.4e-06 27.5 2.6 0.0014 18.5 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP63841.1 - 1.3e-05 24.3 0.2 0.0078 15.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 OAP63841.1 - 3e-05 23.0 1.9 0.02 13.7 1.5 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 OAP63841.1 - 0.00031 19.7 0.1 0.0019 17.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAP63841.1 - 0.0034 16.4 0.2 0.0089 15.1 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 OAP63841.1 - 0.18 10.2 2.0 0.32 9.4 0.4 2.1 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 OAP63841.1 - 0.31 11.0 3.3 1.2 9.1 0.4 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.24 OAP63842.1 - 4.7e-41 140.0 0.0 8.2e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP63842.1 - 5.2e-06 26.6 0.0 0.00059 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAP63842.1 - 4.6e-05 23.1 0.1 0.00026 20.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAP63842.1 - 0.00011 22.1 0.0 0.00059 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 OAP63842.1 - 0.00013 22.0 0.1 0.00095 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 OAP63842.1 - 0.0016 17.4 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 OAP63842.1 - 0.0045 17.8 0.1 0.013 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAP63842.1 - 0.0087 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 OAP63842.1 - 0.0087 15.7 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 OAP63842.1 - 0.018 15.0 0.1 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAP63842.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAP63842.1 - 0.032 14.0 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAP63842.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 OAP63842.1 - 0.048 12.7 0.0 4.1 6.4 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.1 OAP63842.1 - 0.051 13.1 0.3 0.6 9.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain Sigma54_activ_2 PF14532.1 OAP63842.1 - 0.055 13.5 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 OAP63842.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 OAP63842.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Antigen_Bd37 PF11641.3 OAP63842.1 - 0.08 12.2 0.2 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein AAA_11 PF13086.1 OAP63842.1 - 0.084 12.4 0.4 0.84 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 OAP63842.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 OAP63842.1 - 0.1 11.7 0.1 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 OAP63842.1 - 0.11 12.2 0.2 11 5.6 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 OAP63842.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Cpn60_TCP1 PF00118.19 OAP63843.1 - 1.5e-139 465.7 11.2 1.9e-139 465.4 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 OAP63843.1 - 0.035 13.5 0.0 0.086 12.3 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X p450 PF00067.17 OAP63844.1 - 4.5e-51 173.8 0.0 5.8e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Linker_histone PF00538.14 OAP63845.1 - 4.9e-26 90.6 0.6 1.2e-25 89.3 0.4 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family XPG_I PF00867.13 OAP63846.1 - 2.2e-31 107.7 0.0 5.7e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 OAP63846.1 - 5.3e-28 97.2 0.0 1.8e-27 95.5 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 OAP63846.1 - 1.3e-05 25.3 1.2 6.2e-05 23.1 0.0 2.5 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.6 OAP63846.1 - 0.1 11.4 5.7 0.16 10.8 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Acyl-CoA_dh_N PF02771.11 OAP63847.1 - 3.6e-26 91.9 0.2 8.1e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 OAP63847.1 - 4.3e-24 85.3 0.1 7e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP63847.1 - 2.9e-17 61.9 0.0 5.6e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAP63847.1 - 4.2e-06 27.0 0.1 6.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 OAP63848.1 - 1.7e-51 173.2 0.0 1.9e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP63848.1 - 7e-05 22.6 0.0 8.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAP63848.1 - 0.0051 16.6 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 OAP63848.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.7 OAP63849.1 - 9.9e-34 116.5 0.0 3e-33 114.9 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAP63849.1 - 2.7e-21 75.3 0.0 6.5e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 OAP63849.1 - 3.8e-16 59.3 9.5 3.8e-16 59.3 6.6 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAP63849.1 - 1.8e-05 24.7 0.0 4.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAP63849.1 - 0.019 15.5 0.0 0.28 11.7 0.0 2.7 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain RTA1 PF04479.8 OAP63850.1 - 2.3e-55 187.5 10.8 2.3e-55 187.5 7.5 1.7 2 0 0 2 2 2 1 RTA1 like protein LCCL PF03815.14 OAP63851.1 - 3.2e-21 75.1 0.0 6.3e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 LCCL domain DsbB PF02600.11 OAP63851.1 - 0.051 13.3 0.3 0.051 13.3 0.2 2.8 3 1 0 3 3 3 0 Disulfide bond formation protein DsbB Nuc_sug_transp PF04142.10 OAP63852.1 - 1.7e-86 289.3 14.8 2.6e-86 288.7 10.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 OAP63852.1 - 2.7e-10 39.6 13.0 2.7e-10 39.6 9.0 1.9 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 OAP63852.1 - 6.1e-07 29.6 4.2 6.1e-07 29.6 2.9 2.9 3 0 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 OAP63852.1 - 4e-06 26.5 29.9 4.3e-06 26.4 2.4 2.8 2 1 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 OAP63852.1 - 4.2e-06 26.8 25.4 0.00012 22.0 3.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family Fungal_trans_2 PF11951.3 OAP63853.1 - 8.6e-14 50.9 1.1 2.1e-13 49.6 0.7 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain TF_Zn_Ribbon PF08271.7 OAP63854.1 - 0.0052 16.0 0.5 1.4 8.2 0.0 2.7 2 0 0 2 2 2 2 TFIIB zinc-binding DUF3505 PF12013.3 OAP63854.1 - 0.018 15.2 3.1 0.8 9.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) zf-C2H2 PF00096.21 OAP63854.1 - 0.65 10.4 4.7 0.76 10.2 0.1 2.7 2 1 0 2 2 2 0 Zinc finger, C2H2 type UPF0547 PF10571.4 OAP63854.1 - 3 7.6 6.6 1.6 8.4 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 adh_short PF00106.20 OAP63855.1 - 8.6e-26 90.8 0.0 2.6e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 OAP63855.1 - 1.8e-22 80.2 0.0 5.1e-21 75.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP63855.1 - 6.9e-11 42.1 0.0 0.00011 21.9 0.0 2.2 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.5 OAP63855.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 OAP63855.1 - 0.033 13.6 0.0 1.6 8.0 0.0 2.5 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family TPR_12 PF13424.1 OAP63856.1 - 2e-110 360.8 45.4 1.1e-20 73.3 0.6 6.7 1 1 6 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 OAP63856.1 - 3.6e-108 350.8 27.4 2.1e-13 49.7 0.1 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.1 OAP63856.1 - 7.9e-47 153.3 18.8 0.00017 21.1 0.1 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.23 OAP63856.1 - 4.3e-39 130.5 27.2 0.0031 17.0 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_4 PF07721.9 OAP63856.1 - 2.7e-30 101.6 0.1 0.49 10.9 0.0 9.9 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 OAP63856.1 - 1.7e-29 101.2 21.2 4.9e-06 26.0 0.1 5.5 3 1 3 6 6 6 6 TPR repeat TPR_16 PF13432.1 OAP63856.1 - 1.6e-24 85.9 22.9 8.3e-05 23.1 0.2 5.7 2 1 3 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 OAP63856.1 - 1.7e-23 80.6 27.5 0.1 12.5 0.1 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 OAP63856.1 - 1.5e-19 68.5 19.4 0.16 12.2 0.0 9.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 OAP63856.1 - 1.4e-17 62.6 27.9 0.12 13.1 0.2 9.7 5 1 4 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 OAP63856.1 - 6.9e-14 50.4 30.7 0.46 10.3 0.1 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_3 PF07720.7 OAP63856.1 - 1.6e-13 50.1 14.3 0.17 11.6 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 OAP63856.1 - 8.4e-12 45.0 5.2 4.3e-05 23.5 0.1 5.7 1 1 6 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 OAP63856.1 - 4.5e-08 32.6 4.9 3.1 7.1 0.0 5.5 1 1 4 5 5 5 4 26S proteasome subunit RPN7 TPR_19 PF14559.1 OAP63856.1 - 1.1e-05 25.6 34.5 0.32 11.3 1.7 6.5 2 2 7 9 9 9 6 Tetratricopeptide repeat Rab5-bind PF09311.6 OAP63856.1 - 0.00025 20.9 8.7 1.1 9.1 0.0 5.7 1 1 4 6 6 6 1 Rabaptin-like protein LST1 PF05083.8 OAP63856.1 - 0.15 12.0 3.6 2.3 8.2 0.1 3.0 3 0 0 3 3 3 0 LST-1 protein TPR_6 PF13174.1 OAP63856.1 - 2.8 8.6 36.7 69 4.2 0.1 9.6 9 0 0 9 9 9 0 Tetratricopeptide repeat Peptidase_S8 PF00082.17 OAP63857.1 - 1.1e-13 50.9 0.0 1.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DDE_3 PF13358.1 OAP63858.1 - 2.4e-11 43.5 0.2 3.3e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PCI_Csn8 PF10075.4 OAP63858.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 AMP-binding PF00501.23 OAP63860.1 - 2.2e-80 270.1 0.0 2.8e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP63860.1 - 1.9e-13 51.1 0.0 6e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SMC_N PF02463.14 OAP63861.1 - 1.1e-22 80.3 0.0 8.1e-22 77.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAP63861.1 - 2.4e-20 73.7 0.0 2.4e-20 73.7 0.0 4.3 3 1 0 4 4 2 1 AAA domain AAA_21 PF13304.1 OAP63861.1 - 2.7e-05 24.2 0.0 0.00053 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAP63861.1 - 0.00025 20.4 0.0 0.00055 19.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAP63861.1 - 0.033 13.6 1.0 0.15 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 OAP63861.1 - 0.042 14.1 0.0 0.042 14.1 0.0 3.6 3 1 0 3 3 2 0 ABC transporter NPV_P10 PF05531.7 OAP63861.1 - 0.16 12.2 10.7 12 6.1 0.1 5.7 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 OAP63861.1 - 0.34 10.0 9.5 7.6 5.6 0.4 3.8 2 2 2 4 4 4 0 Reovirus sigma C capsid protein AAA_17 PF13207.1 OAP63861.1 - 0.37 11.6 0.0 0.37 11.6 0.0 4.1 4 2 0 4 4 4 0 AAA domain HALZ PF02183.13 OAP63861.1 - 3.2 7.5 11.5 0.29 10.8 1.9 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF2730 PF10805.3 OAP63861.1 - 3.4 7.4 18.1 3.5 7.4 0.9 4.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2730) DUF3573 PF12097.3 OAP63861.1 - 3.6 6.1 5.1 4.8 5.6 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) RGS PF00615.14 OAP63862.1 - 0.00027 21.0 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF4341 PF14241.1 OAP63862.1 - 0.64 9.7 11.1 0.024 14.3 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) ORMDL PF04061.9 OAP63863.1 - 6.4e-60 200.6 5.1 7.6e-60 200.3 3.5 1.1 1 0 0 1 1 1 1 ORMDL family DUF3497 PF12003.3 OAP63863.1 - 0.072 12.4 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3497) DUF2206 PF09971.4 OAP63863.1 - 0.3 9.8 3.2 3.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) DEAD PF00270.24 OAP63865.1 - 4.3e-20 71.8 0.0 7.8e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAP63865.1 - 2.7e-08 33.8 0.0 1.7e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAP63865.1 - 2.8e-06 27.0 0.1 8.1e-06 25.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 OAP63865.1 - 0.019 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CCHC PF00098.18 OAP63866.1 - 0.059 13.3 13.0 0.41 10.6 1.0 3.5 4 0 0 4 4 4 0 Zinc knuckle DUF2890 PF11081.3 OAP63866.1 - 0.67 9.9 11.1 1.4 8.9 7.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-CCHC_6 PF15288.1 OAP63866.1 - 1.6 8.4 9.3 4.1 7.1 0.1 3.3 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAP63866.1 - 2 8.1 25.0 0.4 10.3 0.3 4.7 4 1 0 4 4 4 0 Zinc knuckle CDC45 PF02724.9 OAP63866.1 - 4.2 5.2 13.1 5.7 4.8 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein UCH PF00443.24 OAP63867.1 - 3.2e-43 147.8 0.0 1.1e-42 146.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 OAP63867.1 - 7.7e-35 118.1 0.8 1.3e-12 46.9 0.0 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 OAP63867.1 - 1.4e-12 47.6 5.0 4.6e-10 39.4 3.4 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 OAP63867.1 - 0.033 13.9 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 PUB domain Tim17 PF02466.14 OAP63868.1 - 7.4e-08 32.5 8.3 1.1e-07 31.9 5.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PH PF00169.24 OAP63869.1 - 5.1e-09 36.2 0.1 1.1e-08 35.1 0.1 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 OAP63869.1 - 0.0022 15.6 0.2 0.0032 15.1 0.1 1.1 1 0 0 1 1 1 1 Prominin Abhydrolase_6 PF12697.2 OAP63870.1 - 2.6e-13 50.3 0.9 3.5e-13 49.9 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP63870.1 - 0.00032 20.4 0.0 0.00065 19.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family KAR9 PF08580.5 OAP63871.1 - 8.9 4.4 12.1 11 4.0 8.4 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Macoilin PF09726.4 OAP63871.1 - 10 4.2 9.4 13 3.9 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein CorA PF01544.13 OAP63872.1 - 6.9e-12 44.9 1.6 5.5e-11 42.0 0.6 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Zip PF02535.17 OAP63872.1 - 0.025 13.5 3.8 0.039 12.9 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_S15 PF00312.17 OAP63872.1 - 0.045 13.5 0.5 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S15 CENP-Q PF13094.1 OAP63873.1 - 1.2e-25 90.4 9.7 1.4e-24 86.9 6.7 2.2 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit SCIMP PF15050.1 OAP63873.1 - 0.02 14.8 0.1 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 SCIMP protein DUF2762 PF10960.3 OAP63873.1 - 0.092 12.4 0.5 0.23 11.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) MFS_1 PF07690.11 OAP63874.1 - 3.4e-32 111.5 25.6 3.4e-32 111.5 17.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily PMT PF02366.13 OAP63876.1 - 4.6e-82 275.0 18.1 8.7e-82 274.1 12.6 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAP63876.1 - 5.9e-16 58.5 0.1 7.1e-15 55.0 0.0 2.2 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 OAP63876.1 - 6.3e-08 32.6 11.5 6.3e-08 32.6 8.0 4.3 5 1 0 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Sulfatase PF00884.18 OAP63877.1 - 8.5e-58 195.9 0.0 1.1e-57 195.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 OAP63877.1 - 2.1e-22 78.6 4.3 5.9e-21 74.0 1.5 2.6 1 1 1 2 2 2 2 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 OAP63877.1 - 3.5e-12 46.3 0.2 6.4e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 OAP63877.1 - 3.1e-05 24.2 0.9 0.00014 22.1 0.1 2.4 2 1 1 3 3 3 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 OAP63877.1 - 0.016 13.6 0.0 0.025 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 OAP63877.1 - 0.1 11.9 0.0 3.5 6.9 0.0 2.4 2 1 0 2 2 2 0 Metalloenzyme superfamily BTB PF00651.26 OAP63878.1 - 6.9e-06 26.0 0.0 3.8e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain SnoaL_2 PF12680.2 OAP63879.1 - 0.037 14.4 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain SPO22 PF08631.5 OAP63880.1 - 1e-15 57.5 1.7 3.3e-15 55.9 1.2 1.9 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like HLH PF00010.21 OAP63881.1 - 0.00018 21.1 0.1 0.00054 19.5 0.1 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 OAP63883.1 - 0.0042 17.0 6.6 0.0098 15.8 4.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF4174 PF13778.1 OAP63883.1 - 0.049 13.7 0.2 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) NmrA PF05368.8 OAP63884.1 - 5e-20 71.7 0.0 4.1e-14 52.4 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 OAP63884.1 - 4.5e-07 30.0 0.3 0.008 16.1 0.0 2.8 3 1 0 3 3 3 2 NADH(P)-binding MM_CoA_mutase PF01642.17 OAP63884.1 - 0.043 11.9 0.0 0.063 11.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase DUF883 PF05957.8 OAP63884.1 - 0.081 13.3 0.4 0.081 13.3 0.3 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.20 OAP63886.1 - 3.9e-27 95.0 0.0 4.7e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63886.1 - 8.5e-11 41.4 0.0 1.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP63886.1 - 0.00062 19.5 0.1 0.58 9.8 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.11 OAP63886.1 - 0.015 15.2 0.0 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.9 OAP63886.1 - 0.027 13.5 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4618 PF15397.1 OAP63887.1 - 0.0019 17.5 1.5 0.0035 16.7 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Synaptonemal_3 PF15191.1 OAP63887.1 - 0.047 13.4 0.3 0.13 12.0 0.1 1.8 1 1 0 1 1 1 0 Synaptonemal complex central element protein 3 DUF746 PF05344.6 OAP63887.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Apolipoprotein PF01442.13 OAP63887.1 - 0.33 10.4 2.7 0.46 9.9 0.5 2.1 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain Cortex-I_coil PF09304.5 OAP63887.1 - 0.39 10.7 2.9 0.63 10.0 0.9 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF148 PF02520.12 OAP63887.1 - 0.72 9.6 4.5 3 7.6 2.0 2.6 2 2 1 3 3 3 0 Domain of unknown function DUF148 YgaB PF14182.1 OAP63887.1 - 1.3 9.2 4.3 2 8.7 0.1 2.9 3 1 0 3 3 3 0 YgaB-like protein APH PF01636.18 OAP63888.1 - 0.0016 18.2 0.4 0.013 15.2 0.3 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.24 OAP63889.1 - 1.7e-14 54.1 0.0 3.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAP63889.1 - 0.036 14.3 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 OAP63889.1 - 0.065 12.9 0.3 0.59 9.8 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAP63889.1 - 0.11 12.6 0.1 0.37 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAP63889.1 - 0.12 13.2 0.1 0.5 11.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 OAP63889.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein eIF-3_zeta PF05091.7 OAP63890.1 - 8.3e-194 644.9 0.1 1.3e-193 644.3 0.0 1.2 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2530 PF10745.4 OAP63890.1 - 0.48 10.4 2.8 1.1 9.2 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Pirin PF02678.11 OAP63891.1 - 3.6e-31 107.1 0.1 9.1e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 OAP63891.1 - 4.9e-25 87.6 0.0 6.6e-24 83.9 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 OAP63891.1 - 2.7e-08 33.2 0.4 6.3e-05 22.3 0.2 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 OAP63891.1 - 0.066 12.6 0.3 3.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF861) ATP_bind_2 PF03668.10 OAP63892.1 - 2.6e-05 23.4 0.0 4.6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 P-loop ATPase protein family Zn_clus PF00172.13 OAP63893.1 - 3.9e-10 39.4 11.2 7.3e-10 38.5 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP63893.1 - 0.00087 18.2 2.0 0.0091 14.8 1.1 2.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 OAP63894.1 - 1.9e-23 83.6 0.0 3.7e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP63894.1 - 1.7e-20 72.7 0.1 3.4e-18 65.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP63894.1 - 7.1e-09 35.0 0.2 3.5e-06 26.1 0.0 3.7 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP63894.1 - 1.8e-07 31.0 0.0 6e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP63894.1 - 0.00067 19.4 0.2 0.0042 16.8 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding adh_short PF00106.20 OAP63895.1 - 7.6e-24 84.5 2.8 1.3e-23 83.7 1.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP63895.1 - 9.2e-10 38.4 5.1 4e-09 36.3 0.1 2.6 2 1 1 3 3 3 1 KR domain adh_short_C2 PF13561.1 OAP63895.1 - 1.4e-06 28.2 0.1 3.8e-06 26.8 0.1 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP63895.1 - 0.00031 20.2 0.1 0.00069 19.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 OAP63895.1 - 0.00033 19.8 0.0 0.00062 18.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 OAP63895.1 - 0.0083 15.8 4.8 0.015 15.1 0.2 2.9 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ELFV_dehydrog PF00208.16 OAP63895.1 - 0.0091 15.6 0.2 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ldh_1_N PF00056.18 OAP63895.1 - 0.12 12.1 0.9 0.39 10.5 0.6 1.8 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glu_synthase PF01645.12 OAP63895.1 - 0.35 9.7 2.1 7.4 5.3 0.1 2.2 2 0 0 2 2 2 0 Conserved region in glutamate synthase MFS_1 PF07690.11 OAP63896.1 - 3.6e-28 98.3 31.3 4.5e-28 97.9 21.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABM PF03992.11 OAP63897.1 - 1.6e-05 24.8 0.3 0.048 13.6 0.2 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dabb PF07876.7 OAP63897.1 - 4.4e-05 23.8 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 2 Stress responsive A/B Barrel Domain Oxidored_FMN PF00724.15 OAP63898.1 - 2.4e-71 240.5 0.0 6.9e-68 229.1 0.0 2.3 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Lactamase_B PF00753.22 OAP63899.1 - 8.3e-13 48.4 0.3 1e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP63899.1 - 0.00018 21.1 0.3 0.00035 20.1 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.20 OAP63900.1 - 9.8e-24 84.1 5.4 1.5e-23 83.5 3.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP63900.1 - 2.1e-08 34.0 2.9 3.5e-08 33.3 2.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP63900.1 - 0.014 14.8 0.3 0.021 14.2 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aldolase_II PF00596.16 OAP63901.1 - 2.1e-46 157.8 0.0 2.6e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.13 OAP63902.1 - 1.8e-27 95.8 0.1 3.4e-27 94.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63902.1 - 6.3e-07 29.1 7.7 1.1e-06 28.3 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps4_C PF09336.5 OAP63902.1 - 0.012 15.4 0.1 0.13 12.2 0.0 2.7 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain adh_short_C2 PF13561.1 OAP63903.1 - 1e-30 107.2 2.4 1.2e-30 107.0 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP63903.1 - 1.3e-29 103.2 4.9 1.7e-29 102.8 3.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP63903.1 - 2.5e-13 50.0 3.7 3.6e-13 49.5 2.6 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 OAP63903.1 - 1.9e-05 23.8 0.0 0.00093 18.2 0.2 2.0 1 1 0 2 2 2 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 OAP63903.1 - 0.00028 20.6 0.5 0.00028 20.6 0.3 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 OAP63903.1 - 0.00028 19.8 0.1 0.00049 19.0 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAP63903.1 - 0.00028 20.9 0.5 0.00028 20.9 0.4 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 OAP63903.1 - 0.00038 19.9 0.8 0.0023 17.3 0.6 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 OAP63903.1 - 0.01 15.6 0.3 0.022 14.6 0.2 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF2673 PF10880.3 OAP63903.1 - 0.035 14.1 0.4 0.11 12.5 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) UDPG_MGDP_dh_N PF03721.9 OAP63903.1 - 0.047 13.0 0.4 0.2 11.0 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.19 OAP63904.1 - 2.4e-75 253.8 20.3 2.7e-75 253.6 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63904.1 - 1.4e-22 79.8 50.4 8.2e-19 67.5 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAD PF02109.11 OAP63904.1 - 1.3 9.1 7.7 0.58 10.2 0.1 2.8 2 1 1 3 3 3 0 DAD family Flavin_Reduct PF01613.13 OAP63905.1 - 2.4e-23 82.7 0.2 3.3e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.20 OAP63907.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase T4-Gluco-transf PF09198.5 OAP63907.1 - 0.044 13.1 0.1 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase Fungal_trans_2 PF11951.3 OAP63908.1 - 0.0056 15.3 0.2 0.088 11.3 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Flavin_Reduct PF01613.13 OAP63909.1 - 1.5e-26 93.1 0.0 1.7e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain FAD_binding_3 PF01494.14 OAP63910.1 - 5.2e-22 78.3 0.0 8.8e-20 71.0 0.0 2.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 OAP63910.1 - 0.00018 20.4 0.0 0.00027 19.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 OAP63910.1 - 0.00022 20.3 0.1 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAP63910.1 - 0.038 13.7 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAP63910.1 - 0.07 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP63910.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_C2 PF00648.16 OAP63911.1 - 2e-19 69.7 0.0 3.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 OAP63911.1 - 1.1e-15 57.5 0.0 3e-13 49.6 0.0 2.4 2 0 0 2 2 2 2 Calpain large subunit, domain III DUF4164 PF13747.1 OAP63911.1 - 0.053 13.6 0.4 0.098 12.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Mito_carr PF00153.22 OAP63912.1 - 1.4e-57 191.3 0.5 8.5e-22 76.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF925 PF06042.6 OAP63912.1 - 0.023 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF925) GCD14 PF08704.5 OAP63913.1 - 4.3e-08 32.9 0.0 3.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Metallophos PF00149.23 OAP63914.1 - 2.4e-13 49.9 1.6 4.3e-13 49.1 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NAD_binding_1 PF00175.16 OAP63915.1 - 1.1e-05 25.9 0.6 8.4e-05 23.0 0.4 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 OAP63915.1 - 5.5e-05 23.1 0.1 0.0076 16.1 0.1 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 OAP63915.1 - 0.00074 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Amino_oxidase PF01593.19 OAP63916.1 - 1e-96 324.8 0.0 1.9e-96 323.8 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 OAP63916.1 - 2e-09 37.4 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 OAP63916.1 - 2.2e-08 34.0 0.0 7.3e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 OAP63916.1 - 2.7e-06 27.5 5.1 2.7e-05 24.3 2.8 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 OAP63916.1 - 4.1e-06 25.9 0.0 1.8e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HMG_box_2 PF09011.5 OAP63916.1 - 6e-06 26.5 3.2 1.8e-05 25.0 2.2 1.9 1 0 0 1 1 1 1 HMG-box domain NAD_binding_9 PF13454.1 OAP63916.1 - 0.00028 20.6 0.0 0.016 15.0 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP63916.1 - 0.012 15.5 0.1 0.047 13.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP63916.1 - 0.027 14.5 0.0 0.41 10.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyridox_oxidase PF01243.15 OAP63917.1 - 0.0056 16.6 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 OAP63919.1 - 1.9e-38 132.1 0.0 2.6e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63919.1 - 4.4e-13 48.8 0.0 7.4e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP63919.1 - 0.0084 15.8 0.0 0.031 13.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAP63919.1 - 0.017 14.1 0.0 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Abhydrolase_6 PF12697.2 OAP63921.1 - 1.1e-29 103.9 0.1 1.9e-29 103.1 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP63921.1 - 3.1e-13 49.7 0.0 2.5e-12 46.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP63921.1 - 4.2e-11 42.8 0.0 1.7e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 OAP63921.1 - 0.023 13.9 0.0 0.56 9.4 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Glucosamine_iso PF01182.15 OAP63922.1 - 6e-59 199.1 0.0 7.2e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RRM_1 PF00076.17 OAP63923.1 - 5.3e-15 54.7 0.0 2.7e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP63923.1 - 9.2e-07 28.7 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP63923.1 - 0.03 14.1 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myosin_HC-like PF07058.6 OAP63923.1 - 1.6 7.7 14.6 2.6 7.0 10.1 1.3 1 0 0 1 1 1 0 Myosin II heavy chain-like MIP-T3 PF10243.4 OAP63923.1 - 2.3 6.5 18.2 4.1 5.7 12.6 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TFIIA PF03153.8 OAP63923.1 - 2.3 8.0 20.3 4.2 7.1 14.1 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.1 OAP63924.1 - 2.7e-22 79.1 0.0 9.5e-22 77.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP63924.1 - 8e-11 41.7 0.0 0.00018 21.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 OAP63924.1 - 1e-10 41.9 0.0 2.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP63924.1 - 1.9e-10 41.0 0.0 2.9e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP63924.1 - 5.7e-09 36.5 0.0 3.3e-07 30.8 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP63924.1 - 2.6e-05 24.2 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP63924.1 - 0.0002 20.7 0.0 0.0081 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 OAP63924.1 - 0.0042 17.4 0.0 0.021 15.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAP63924.1 - 0.0045 16.0 0.0 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 OAP63924.1 - 0.007 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.7 OAP63924.1 - 0.0083 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.8 OAP63924.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 OAP63924.1 - 0.036 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase 4HBT_3 PF13622.1 OAP63924.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Ribosomal_L29 PF00831.18 OAP63924.1 - 0.071 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein Methyltransf_2 PF00891.13 OAP63925.1 - 1.1e-20 73.8 0.0 1.4e-19 70.2 0.0 2.2 1 1 0 1 1 1 1 O-methyltransferase Phage_lysozyme PF00959.14 OAP63927.1 - 0.00018 21.7 0.1 0.00033 20.9 0.1 1.6 1 1 0 1 1 1 1 Phage lysozyme MMR_HSR1 PF01926.18 OAP63928.1 - 2.9e-05 23.9 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PTS_EIIC PF02378.13 OAP63928.1 - 0.045 12.5 0.1 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF3597 PF12200.3 OAP63928.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Peroxin-13_N PF04088.8 OAP63929.1 - 2.1e-52 177.2 0.0 4.6e-52 176.1 0.0 1.6 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 OAP63929.1 - 5.5e-09 35.2 0.0 9.2e-09 34.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAP63929.1 - 5.6e-09 35.3 0.0 9.4e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 OAP63929.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GRP PF07172.6 OAP63929.1 - 3.2 8.2 20.8 8 7.0 14.0 1.9 2 0 0 2 2 2 0 Glycine rich protein family Vps8 PF12816.2 OAP63930.1 - 1.3e-54 184.4 0.0 2.3e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 OAP63930.1 - 5.6e-05 22.7 0.0 0.05 13.2 0.0 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 OAP63930.1 - 0.0056 16.4 0.3 0.015 15.1 0.2 1.7 1 0 0 1 1 1 1 Ring finger domain Syntaxin-18_N PF10496.4 OAP63930.1 - 0.016 15.0 0.4 1.1 9.1 0.0 3.0 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus zf-RING_5 PF14634.1 OAP63930.1 - 0.058 13.1 0.6 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAP63930.1 - 0.17 11.9 0.2 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_16 PF00722.16 OAP63931.1 - 1.9e-08 33.8 0.1 6e-08 32.1 0.0 1.8 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 DUF4448 PF14610.1 OAP63933.1 - 9.8e-05 21.9 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 OAP63933.1 - 0.0026 17.4 0.1 0.0038 16.9 0.1 1.1 1 0 0 1 1 1 1 Rifin/stevor family SKG6 PF08693.5 OAP63933.1 - 0.0062 15.8 0.1 0.015 14.5 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 OAP63933.1 - 0.014 15.0 1.4 0.014 15.0 0.9 2.2 2 1 1 3 3 3 0 TMEM154 protein family DUF3609 PF12259.3 OAP63933.1 - 0.018 13.7 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF2749 PF10907.3 OAP63933.1 - 6.7 6.6 6.7 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF2976 PF11190.3 OAP63934.1 - 0.022 14.2 0.2 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) EF-hand_6 PF13405.1 OAP63935.1 - 3.8e-08 32.5 0.0 0.0012 18.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 OAP63935.1 - 2.1e-07 29.7 0.0 0.0023 17.1 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 OAP63935.1 - 2.9e-07 29.5 0.5 0.00047 19.3 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 OAP63935.1 - 2.5e-06 27.5 0.1 0.0001 22.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAP63935.1 - 0.073 12.7 0.0 0.82 9.3 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Afi1 PF07792.7 OAP63936.1 - 5.6e-59 198.3 0.0 8.8e-59 197.6 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 OAP63936.1 - 2e-38 130.5 0.0 6.2e-38 128.9 0.0 1.8 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.4 OAP63936.1 - 9.6e-09 34.1 0.0 0.02 13.3 0.0 3.8 3 1 1 4 4 4 3 Transport protein Avl9 TFIIF_alpha PF05793.7 OAP63936.1 - 0.0038 15.6 1.8 0.0061 14.9 1.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2347 PF09804.4 OAP63936.1 - 0.017 14.4 0.0 0.054 12.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Nop14 PF04147.7 OAP63936.1 - 0.8 7.5 5.7 1.1 7.0 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 OAP63939.1 - 1.1e-36 126.2 49.1 4.8e-35 120.9 28.2 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP63939.1 - 2.2e-09 36.4 26.1 1e-08 34.2 10.2 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter Cation_ATPase_C PF00689.16 OAP63939.1 - 0.0004 19.9 8.6 0.0004 19.9 6.0 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Chitin_synth_2 PF03142.10 OAP63942.1 - 4.7e-292 969.0 0.1 2e-291 966.9 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 OAP63942.1 - 9.1e-18 64.6 2.1 5.3e-17 62.1 1.4 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAP63942.1 - 1.2e-15 57.9 0.0 1.2e-12 48.1 0.0 2.6 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 OAP63942.1 - 1.2e-07 31.3 0.3 4.9e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 OAP63942.1 - 4.4e-05 22.8 0.0 0.00082 18.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAP63942.1 - 0.0038 16.9 0.0 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.7 OAP63943.1 - 2.7e-37 126.3 30.0 1.2e-05 25.7 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat MFS_1 PF07690.11 OAP63944.1 - 5.4e-39 133.8 28.9 5.4e-39 133.8 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RPAP3_C PF13877.1 OAP63945.1 - 0.012 15.5 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 UPF0075 PF03702.9 OAP63946.1 - 7.3e-72 242.2 0.0 3.6e-69 233.3 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0075) Sugar_tr PF00083.19 OAP63947.1 - 3.6e-74 249.9 29.9 4.2e-74 249.7 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP63947.1 - 2.6e-18 65.8 23.3 2.6e-18 65.8 16.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 OAP63948.1 - 1.3e-67 227.6 0.0 1.5e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2757 PF10955.3 OAP63948.1 - 0.061 13.5 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) RHH_1 PF01402.16 OAP63948.1 - 0.073 12.9 0.3 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family AMP-binding PF00501.23 OAP63949.1 - 6.7e-88 294.8 0.0 8.4e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP63949.1 - 2e-11 44.6 0.0 5.2e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 OAP63951.1 - 6.3e-34 117.2 66.6 7.1e-34 117.0 44.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP63951.1 - 3e-09 35.9 15.9 3e-09 35.9 11.0 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter HATPase_c PF02518.21 OAP63953.1 - 6.7e-27 93.4 0.2 1.2e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAP63953.1 - 9.1e-21 73.6 0.2 3.4e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 OAP63953.1 - 4.8e-17 61.9 0.0 1.5e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 OAP63953.1 - 3.4e-16 59.5 0.0 2.9e-10 40.4 0.0 4.5 4 0 0 4 4 4 2 PAS domain PAS_3 PF08447.6 OAP63953.1 - 1.8e-15 56.7 0.4 5e-15 55.3 0.2 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 OAP63953.1 - 2.7e-12 46.7 0.0 4e-07 30.0 0.0 4.5 4 1 0 4 4 4 2 PAS fold PAS PF00989.19 OAP63953.1 - 6.6e-07 29.1 0.0 0.035 13.8 0.0 4.1 4 0 0 4 4 4 2 PAS fold HATPase_c_3 PF13589.1 OAP63953.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4172 PF13776.1 OAP63953.1 - 0.077 13.0 0.3 0.27 11.3 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) UQ_con PF00179.21 OAP63954.1 - 4.8e-43 145.9 0.1 1.6e-28 98.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAP63954.1 - 2.6e-07 30.4 0.0 0.0069 16.1 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.17 OAP63954.1 - 0.0013 18.5 0.7 0.92 9.4 0.0 3.0 2 1 0 2 2 2 2 RWD domain UEV PF05743.8 OAP63954.1 - 0.0023 17.6 0.1 0.0073 15.9 0.0 1.8 2 0 0 2 2 2 1 UEV domain DUF1528 PF07515.6 OAP63954.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1528) 3Beta_HSD PF01073.14 OAP63955.1 - 8.5e-40 136.2 0.0 2.7e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAP63955.1 - 6.5e-18 65.0 0.0 3.8e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP63955.1 - 2.2e-13 49.6 0.0 1.5e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 OAP63955.1 - 7.2e-09 34.9 0.1 6.1e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 OAP63955.1 - 0.0018 17.2 0.0 0.81 8.5 0.0 2.8 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAP63955.1 - 0.003 17.5 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 OAP63955.1 - 0.018 14.9 0.0 1.8 8.4 0.0 2.8 2 1 0 2 2 2 0 short chain dehydrogenase Pkinase PF00069.20 OAP63956.1 - 4.8e-61 206.1 0.0 3.6e-39 134.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63956.1 - 2.3e-26 92.4 0.0 2.3e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 OAP63956.1 - 2.5e-12 46.7 0.0 6.5e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 OAP63956.1 - 7.4e-08 31.6 0.0 1.5e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 OAP63956.1 - 5.3e-06 26.3 0.1 0.0039 16.9 0.1 3.2 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 OAP63956.1 - 0.0071 15.4 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 OAP63956.1 - 0.016 15.6 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 OAP63956.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS PF00989.19 OAP63956.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 OAP63956.1 - 0.11 11.2 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PTR2 PF00854.16 OAP63958.1 - 8.9e-52 176.1 11.0 1.2e-50 172.4 7.7 2.2 1 1 0 1 1 1 1 POT family DUF4094 PF13334.1 OAP63958.1 - 0.013 15.8 1.7 0.65 10.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) CsrA PF02599.11 OAP63958.1 - 0.18 11.5 0.4 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Global regulator protein family zf-RING_2 PF13639.1 OAP63959.1 - 7e-13 48.1 7.2 1.1e-12 47.6 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAP63959.1 - 1.2e-07 31.7 3.1 2.5e-07 30.6 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAP63959.1 - 5.2e-07 29.2 5.3 8.5e-07 28.5 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP63959.1 - 1.8e-05 24.3 4.8 2.8e-05 23.7 3.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAP63959.1 - 2e-05 24.4 6.7 3.3e-05 23.8 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP63959.1 - 2.2e-05 24.0 3.1 3.4e-05 23.4 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAP63959.1 - 0.0022 17.8 4.2 0.0049 16.6 2.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 OAP63959.1 - 0.0053 16.3 7.6 0.0087 15.6 5.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Neur_chan_memb PF02932.11 OAP63959.1 - 0.11 12.3 0.1 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PHD PF00628.24 OAP63959.1 - 0.15 11.8 6.8 0.3 10.7 4.7 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 OAP63959.1 - 0.35 10.8 4.3 1 9.3 3.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 OAP63959.1 - 0.51 10.2 4.3 1.4 8.8 3.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 OAP63959.1 - 0.56 10.2 6.6 0.99 9.5 4.6 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 OAP63959.1 - 9.8 5.9 9.7 0.57 9.9 1.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 TRI12 PF06609.8 OAP63960.1 - 1.6e-25 89.4 23.0 2.3e-25 88.8 16.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP63960.1 - 4.1e-21 75.0 38.2 4.1e-21 75.0 26.5 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MscL PF01741.13 OAP63960.1 - 0.021 14.9 7.0 0.94 9.6 0.0 4.5 4 1 1 5 5 5 0 Large-conductance mechanosensitive channel, MscL Fst_toxin PF13955.1 OAP63960.1 - 0.022 14.4 5.0 0.089 12.4 3.5 2.1 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system p450 PF00067.17 OAP63961.1 - 6.2e-52 176.6 0.0 8.1e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 OAP63962.1 - 9.5e-41 139.6 45.9 3e-40 138.0 31.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP63962.1 - 0.63 9.8 9.0 5.5 6.8 0.1 2.8 2 0 0 2 2 2 0 MFS_1 like family Fungal_trans PF04082.13 OAP63963.1 - 4e-17 61.9 0.0 6.7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP63963.1 - 7.1e-10 38.6 9.4 7.1e-10 38.6 6.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 OAP63964.1 - 0.00085 19.4 4.0 0.0016 18.6 0.8 2.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FliO PF04347.8 OAP63964.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO TAFII55_N PF04658.8 OAP63965.1 - 1e-46 158.3 0.0 2.3e-46 157.2 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region ApoL PF05461.6 OAP63965.1 - 0.0053 16.0 0.1 0.0075 15.5 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein L DUF1664 PF07889.7 OAP63965.1 - 0.054 13.2 3.3 0.12 12.1 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pox_RNA_Pol_19 PF05320.7 OAP63965.1 - 2.9 7.5 10.3 7 6.3 7.1 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Bromo_TP PF07524.8 OAP63966.1 - 2.5e-11 43.1 0.0 4.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TPR_12 PF13424.1 OAP63968.1 - 0.072 13.0 0.8 22 5.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ferritin_2 PF13668.1 OAP63969.1 - 5e-19 68.6 0.0 1.1e-18 67.4 0.0 1.5 2 0 0 2 2 2 1 Ferritin-like domain Ubiq_cyt_C_chap PF03981.7 OAP63970.1 - 6.4e-28 97.3 0.3 2.5e-26 92.1 0.4 2.1 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Lamp PF01299.12 OAP63971.1 - 0.22 10.6 1.0 0.28 10.2 0.7 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DnaJ PF00226.26 OAP63972.1 - 1.8e-23 82.0 1.5 1.8e-23 82.0 1.0 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 OAP63972.1 - 3.4e-15 55.8 18.0 6e-15 55.0 12.5 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 OAP63972.1 - 8.4e-14 51.2 0.0 2.4e-12 46.5 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain SRR PF07709.6 OAP63972.1 - 0.019 15.0 0.3 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 Seven Residue Repeat HypA PF01155.14 OAP63972.1 - 0.092 12.4 7.3 2.1 8.0 0.6 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 OAP63972.1 - 1.6 8.8 6.4 2.7 8.1 0.5 2.3 2 0 0 2 2 2 0 Stc1 domain IMS_C PF11799.3 OAP63973.1 - 0.041 13.8 2.8 0.61 10.0 1.1 2.1 1 1 1 2 2 2 0 impB/mucB/samB family C-terminal domain CCDC50_N PF15295.1 OAP63973.1 - 0.079 12.8 4.3 0.12 12.3 2.8 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF2326 PF10088.4 OAP63976.1 - 0.0032 17.1 0.2 0.43 10.2 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2326) DUF1054 PF06335.7 OAP63976.1 - 0.12 11.9 1.3 0.18 11.4 0.7 1.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) Fungal_trans PF04082.13 OAP63977.1 - 1.5e-13 50.2 3.7 5.1e-13 48.4 0.6 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain MMS19_N PF14500.1 OAP63978.1 - 9e-91 303.7 0.5 3.9e-90 301.6 0.0 2.4 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 OAP63978.1 - 2.9e-89 299.6 11.2 7.1e-88 295.1 3.5 3.2 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 OAP63978.1 - 0.00021 21.4 11.9 0.52 10.6 0.1 6.7 7 1 1 8 8 8 2 HEAT repeats Cnd1 PF12717.2 OAP63978.1 - 0.063 13.1 1.2 4.5 7.0 0.0 4.0 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Acyl-CoA_dh_C PF12806.2 OAP63978.1 - 0.069 13.0 0.9 0.24 11.2 0.1 2.3 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like TcdB_N PF12918.2 OAP63978.1 - 0.087 12.9 0.6 9.7 6.3 0.0 3.0 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain HEAT_EZ PF13513.1 OAP63978.1 - 0.092 13.2 11.9 0.59 10.6 0.0 6.1 7 1 0 7 7 7 0 HEAT-like repeat Complex1_51K PF01512.12 OAP63978.1 - 0.16 11.6 0.2 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit HEAT PF02985.17 OAP63978.1 - 0.31 11.2 5.3 15 5.9 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat OB_NTP_bind PF07717.11 OAP63979.1 - 7e-30 103.1 0.0 2e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAP63979.1 - 4.4e-24 84.4 0.1 4.4e-24 84.4 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAP63979.1 - 1e-12 47.7 0.0 2.9e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP63979.1 - 5.2e-07 29.2 0.1 1.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 OAP63979.1 - 2e-05 23.6 0.1 6e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 OAP63979.1 - 4.1e-05 23.7 0.0 0.00014 21.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 OAP63979.1 - 0.0026 17.7 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 OAP63979.1 - 0.0053 16.4 0.3 0.05 13.3 0.0 2.7 3 0 0 3 3 3 1 Part of AAA domain ResIII PF04851.10 OAP63979.1 - 0.03 14.1 3.1 1.1 9.0 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 OAP63979.1 - 0.041 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 OAP63979.1 - 0.042 14.1 3.1 0.059 13.6 0.1 2.6 1 1 1 2 2 2 0 ABC transporter AAA_23 PF13476.1 OAP63979.1 - 0.08 13.2 0.0 0.08 13.2 0.0 3.6 1 1 1 2 2 1 0 AAA domain cobW PF02492.14 OAP63979.1 - 0.12 11.8 0.4 2 7.8 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain THF_DHG_CYH PF00763.18 OAP63980.1 - 1e-16 61.0 0.0 2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 OAP63980.1 - 1.1e-11 44.0 0.1 1.2e-08 34.2 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RTBV_P12 PF06361.6 OAP63980.1 - 0.072 13.3 0.4 0.18 12.0 0.3 1.6 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein bZIP_1 PF00170.16 OAP63982.1 - 3.9e-06 26.7 12.2 6.4e-06 26.0 8.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.3 OAP63982.1 - 0.00024 20.8 1.0 0.00039 20.1 0.7 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF3631 PF12307.3 OAP63982.1 - 0.00036 20.4 1.2 0.00052 19.9 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3631) DUF4618 PF15397.1 OAP63982.1 - 0.0024 17.2 1.0 0.0031 16.8 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Laps PF10169.4 OAP63982.1 - 0.0088 16.2 1.9 0.012 15.8 1.3 1.2 1 0 0 1 1 1 1 Learning-associated protein IncA PF04156.9 OAP63982.1 - 0.014 14.9 5.2 0.021 14.4 3.6 1.2 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 OAP63982.1 - 0.024 14.4 11.7 0.06 13.1 7.6 1.9 1 1 1 2 2 2 0 Basic region leucine zipper HSP70 PF00012.15 OAP63982.1 - 0.034 12.0 0.2 0.042 11.7 0.1 1.0 1 0 0 1 1 1 0 Hsp70 protein SPX PF03105.14 OAP63982.1 - 0.075 12.7 2.2 0.1 12.3 1.5 1.2 1 0 0 1 1 1 0 SPX domain bZIP_Maf PF03131.12 OAP63982.1 - 0.077 13.3 6.6 0.16 12.2 4.6 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2400 PF09674.5 OAP63982.1 - 0.094 12.4 0.7 0.13 11.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Cyt-b5 PF00173.23 OAP63983.1 - 5.2e-19 67.8 0.1 5.7e-19 67.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 OAP63983.1 - 0.027 14.3 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H bZIP_1 PF00170.16 OAP63984.1 - 3.8e-06 26.7 3.7 3.8e-06 26.7 2.6 2.0 2 1 1 3 3 3 1 bZIP transcription factor PBP_sp32 PF07222.7 OAP63984.1 - 0.093 11.8 0.4 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ribosomal_L44 PF00935.14 OAP63987.1 - 3.1e-35 120.0 11.6 5.2e-35 119.3 8.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 DUF3813 PF12758.2 OAP63988.1 - 5.8 7.1 10.7 9.1 6.5 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3813) DUF3824 PF12868.2 OAP63989.1 - 4.2e-07 30.9 48.1 4.2e-07 30.9 33.4 8.8 3 3 7 10 10 10 4 Domain of unknwon function (DUF3824) Vac7 PF12751.2 OAP63990.1 - 2.9e-141 470.8 3.4 5.3e-141 469.9 2.4 1.5 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 OMPdecase PF00215.19 OAP63991.1 - 2.5e-69 233.1 0.0 2.9e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pkinase PF00069.20 OAP63992.1 - 7.6e-41 139.9 0.0 2.2e-40 138.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP63992.1 - 1.9e-23 82.8 0.0 3.5e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP63992.1 - 0.016 14.9 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Band_7 PF01145.20 OAP63993.1 - 2.4e-17 63.4 0.2 2.4e-17 63.4 0.1 3.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family Hid1 PF12722.2 OAP63993.1 - 1 6.9 6.5 1.3 6.6 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ADH_zinc_N PF00107.21 OAP63995.1 - 0.067 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP63995.1 - 0.094 13.6 0.0 0.28 12.0 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TBCA PF02970.11 OAP63996.1 - 3e-21 75.3 11.5 3.7e-21 74.9 7.9 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Baculo_PEP_C PF04513.7 OAP63996.1 - 0.084 12.7 0.4 0.097 12.4 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RelB_N PF12910.2 OAP63996.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal zf-C4H2 PF10146.4 OAP63996.1 - 0.16 11.9 6.2 0.17 11.8 4.3 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein FlxA PF14282.1 OAP63996.1 - 0.51 10.2 7.1 2.4 8.1 0.0 2.2 1 1 1 2 2 2 0 FlxA-like protein Syntaxin_2 PF14523.1 OAP63996.1 - 0.89 9.6 5.6 0.57 10.2 0.6 2.2 1 1 1 2 2 2 0 Syntaxin-like protein DUF745 PF05335.8 OAP63996.1 - 0.95 8.9 9.1 1.1 8.7 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Guanylate_kin PF00625.16 OAP63996.1 - 1 8.7 5.5 1.3 8.4 0.6 2.0 1 1 0 2 2 2 0 Guanylate kinase Med9 PF07544.8 OAP63996.1 - 1.4 8.7 7.4 0.36 10.5 0.8 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FlgN PF05130.7 OAP63996.1 - 1.4 9.1 9.4 2.3 8.4 6.4 1.3 1 1 0 1 1 1 0 FlgN protein DUF2570 PF10828.3 OAP63996.1 - 1.5 8.4 6.3 1.8 8.1 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DUF4404 PF14357.1 OAP63996.1 - 2.5 8.5 8.2 0.43 11.0 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) PGBA_C PF15437.1 OAP63996.1 - 2.6 8.2 10.8 0.64 10.1 2.6 2.1 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Phage_GP20 PF06810.6 OAP63996.1 - 2.7 7.3 11.3 0.27 10.6 3.6 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 IncA PF04156.9 OAP63996.1 - 4.5 6.8 8.8 6 6.4 6.1 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 OAP63996.1 - 9.3 4.5 8.4 11 4.2 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) THOC7 PF05615.8 OAP63997.1 - 1.2e-28 100.1 4.5 1.2e-28 100.1 3.1 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 Med30 PF11315.3 OAP63997.1 - 0.015 15.4 4.7 0.03 14.4 3.3 1.5 1 1 0 1 1 1 0 Mediator complex subunit 30 DUF1640 PF07798.6 OAP63997.1 - 0.058 13.4 4.5 5 7.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) AMH_N PF04709.7 OAP63997.1 - 0.072 12.0 0.1 0.072 12.0 0.0 1.7 2 0 0 2 2 2 0 Anti-Mullerian hormone, N terminal region DUF972 PF06156.8 OAP63997.1 - 1.4 9.2 5.5 0.75 10.1 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SYCE1 PF15233.1 OAP63997.1 - 2.3 8.1 10.6 8.4 6.3 6.1 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 TMF_DNA_bd PF12329.3 OAP63997.1 - 2.8 7.8 9.8 0.62 9.9 3.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.7 OAP63997.1 - 6.2 5.1 8.1 8.3 4.7 5.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Elongin_A PF06881.6 OAP63998.1 - 1.6e-24 86.4 0.5 1.6e-24 86.4 0.3 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Mcp5_PH PF12814.2 OAP63999.1 - 5.1e-48 162.0 0.6 9.7e-48 161.1 0.4 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 OAP63999.1 - 0.0054 16.4 8.3 0.0054 16.4 5.7 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein ADIP PF11559.3 OAP63999.1 - 0.18 11.6 16.2 0.055 13.3 3.3 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.10 OAP63999.1 - 0.58 10.1 12.8 1.1 9.2 8.8 1.3 1 0 0 1 1 1 0 Fez1 AAA_13 PF13166.1 OAP63999.1 - 0.75 8.1 6.2 1.1 7.6 4.3 1.1 1 0 0 1 1 1 0 AAA domain Lebercilin PF15619.1 OAP63999.1 - 1.1 8.6 18.9 2.2 7.6 13.1 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 OAP63999.1 - 4.5 6.8 13.4 7.7 6.0 9.3 1.3 1 0 0 1 1 1 0 IncA protein HAD_2 PF13419.1 OAP64000.1 - 1.5e-24 87.2 0.0 3.4e-24 86.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP64000.1 - 5.4e-08 33.5 0.0 6.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP64000.1 - 6.5e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HTH_AraC PF00165.18 OAP64000.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family GST_N_2 PF13409.1 OAP64001.1 - 2.9e-19 68.8 0.0 5.9e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP64001.1 - 1.8e-14 53.3 0.0 3.9e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAP64001.1 - 1.2e-06 28.4 0.1 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP64001.1 - 0.00031 20.8 0.0 0.006 16.7 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAP64001.1 - 0.0006 20.2 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ras PF00071.17 OAP64002.1 - 1.4e-52 177.3 0.2 1.7e-51 173.8 0.1 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 OAP64002.1 - 2.9e-15 56.7 0.0 1.2e-14 54.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 OAP64002.1 - 0.00076 18.7 0.0 0.0015 17.7 0.1 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAP64002.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAP64002.1 - 0.056 12.5 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 OAP64002.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 OAP64002.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin zf-GRF PF06839.7 OAP64003.1 - 0.0024 17.7 5.8 0.0049 16.7 4.0 1.5 1 0 0 1 1 1 1 GRF zinc finger Atg14 PF10186.4 OAP64003.1 - 0.0056 15.6 1.7 0.0089 15.0 1.1 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 OAP64003.1 - 0.044 13.2 1.1 0.092 12.2 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Kinesin PF00225.18 OAP64004.1 - 2.6e-112 374.8 0.0 4.2e-112 374.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 OAP64004.1 - 1.9e-34 118.3 0.1 3.8e-34 117.3 0.1 1.5 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.21 OAP64004.1 - 4.5e-06 26.6 1.7 3.7e-05 23.7 0.1 3.5 4 0 0 4 4 4 1 FHA domain PH PF00169.24 OAP64004.1 - 9e-05 22.6 0.0 0.00054 20.1 0.0 2.4 2 0 0 2 2 2 1 PH domain MIP PF00230.15 OAP64005.1 - 3.9e-46 157.3 14.9 4.8e-46 157.0 10.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein FA_desaturase PF00487.19 OAP64005.1 - 0.21 10.9 13.5 0.12 11.7 5.8 2.6 1 1 1 2 2 2 0 Fatty acid desaturase Vma12 PF11712.3 OAP64005.1 - 0.45 10.2 3.0 6 6.5 0.0 2.4 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RasGEF PF00617.14 OAP64006.1 - 6.1e-43 146.7 0.0 1.3e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Miro PF08477.8 OAP64006.1 - 3.1e-11 43.8 0.0 7.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein RasGEF_N PF00618.15 OAP64006.1 - 3.6e-10 39.8 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 OAP64006.1 - 5.4e-07 29.1 0.0 1.7e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Ras family Arf PF00025.16 OAP64006.1 - 0.0003 20.0 0.0 0.00052 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 OAP64006.1 - 0.0041 15.8 0.2 0.0041 15.8 0.1 1.8 2 0 0 2 2 2 1 G-protein alpha subunit Arch_ATPase PF01637.13 OAP64006.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Laminin_I PF06008.9 OAP64007.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain I Nfu_N PF08712.6 OAP64008.1 - 2.1e-28 97.7 0.0 6.6e-28 96.1 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 OAP64008.1 - 4.8e-22 77.5 0.0 7.6e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.7 OAP64009.1 - 4.8e-31 106.6 2.3 1e-30 105.5 1.6 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Ribosomal_L15e PF00827.12 OAP64011.1 - 3.6e-91 303.8 10.3 4.5e-91 303.5 7.2 1.1 1 0 0 1 1 1 1 Ribosomal L15 zf-CSL PF05207.8 OAP64012.1 - 1.5e-23 82.0 0.5 2e-23 81.6 0.4 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 OAP64012.1 - 0.0071 16.2 0.2 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Zinc ribbon domain AKAP7_NLS PF10469.4 OAP64013.1 - 1.6e-18 67.1 0.0 2.4e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 OAP64013.1 - 0.00033 20.4 0.3 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 OAP64013.1 - 0.00061 19.7 0.6 2.7 8.0 0.0 3.6 3 0 0 3 3 3 2 LigT like Phosphoesterase PaREP1 PF05942.6 OAP64014.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family AdoHcyase PF05221.12 OAP64015.1 - 4.6e-136 452.0 0.2 5.3e-136 451.8 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 OAP64015.1 - 3.9e-84 280.4 4.7 6.3e-84 279.7 3.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAP64015.1 - 1.6e-07 30.6 0.2 3.2e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 OAP64015.1 - 0.001 19.0 0.1 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 OAP64015.1 - 0.0026 17.3 0.7 0.0048 16.5 0.3 1.6 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 OAP64015.1 - 0.0046 16.3 0.3 0.0082 15.5 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 OAP64015.1 - 0.078 12.8 1.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 short chain dehydrogenase DUF4448 PF14610.1 OAP64015.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) OSCP PF00213.13 OAP64017.1 - 2.9e-45 154.2 1.1 3.4e-45 154.0 0.8 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit vATP-synt_E PF01991.13 OAP64017.1 - 0.072 12.3 0.3 0.12 11.6 0.1 1.4 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Glyco_hydro_63 PF03200.11 OAP64019.1 - 7.2e-07 27.4 8.4 4.9e-06 24.6 0.8 3.6 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase SNF2_N PF00176.18 OAP64020.1 - 5.2e-67 225.7 0.0 9.6e-67 224.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP64020.1 - 1.6e-08 34.2 0.0 3.5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAP64020.1 - 2.4e-08 33.6 0.0 1.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 OAP64020.1 - 0.0004 20.0 5.5 0.00078 19.1 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Sgf11 PF08209.6 OAP64020.1 - 0.14 11.5 1.9 8.3 5.8 0.2 2.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C3HC4_3 PF13920.1 OAP64020.1 - 0.49 10.1 4.9 1.5 8.5 3.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP64020.1 - 1.3 8.9 4.4 3.1 7.7 3.0 1.7 1 0 0 1 1 1 0 Ring finger domain Zn-ribbon_8 PF09723.5 OAP64020.1 - 3.8 7.5 5.0 10 6.1 2.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Aldo_ket_red PF00248.16 OAP64022.1 - 8.1e-43 146.2 0.0 1e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family bZIP_1 PF00170.16 OAP64023.1 - 2.1e-09 37.2 9.6 4e-09 36.3 6.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 OAP64023.1 - 8.6e-07 28.9 3.8 4.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_Maf PF03131.12 OAP64023.1 - 1.8e-06 28.1 3.8 2.7e-06 27.5 2.7 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 OAP64023.1 - 0.00067 19.4 9.3 0.0014 18.3 6.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DUF2514 PF10721.4 OAP64023.1 - 0.042 13.5 7.3 0.072 12.7 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TMF_TATA_bd PF12325.3 OAP64023.1 - 0.043 13.5 3.4 0.068 12.9 2.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding UPF0137 PF03677.8 OAP64023.1 - 0.056 12.9 0.1 0.078 12.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) ADIP PF11559.3 OAP64023.1 - 0.067 13.0 7.7 0.12 12.2 5.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.9 OAP64023.1 - 0.071 12.7 3.6 0.15 11.6 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IncA PF04156.9 OAP64023.1 - 0.077 12.5 1.1 0.11 12.1 0.8 1.2 1 0 0 1 1 1 0 IncA protein CCDC155 PF14662.1 OAP64023.1 - 0.085 12.4 4.9 0.12 11.9 3.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 OAP64023.1 - 0.25 11.7 1.6 0.38 11.1 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 OAP64023.1 - 0.25 9.1 0.1 0.29 8.9 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMSTEN PF07988.7 OAP64023.1 - 1.9 7.8 5.9 3.6 6.9 0.0 3.1 3 0 0 3 3 3 0 LMSTEN motif Phosducin PF02114.11 OAP64024.1 - 9.7e-12 44.1 0.1 1.9e-11 43.1 0.1 1.3 1 1 0 1 1 1 1 Phosducin Bd3614_N PF14442.1 OAP64024.1 - 0.021 14.7 2.3 0.021 14.7 1.6 2.0 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal CENP-B_dimeris PF09026.5 OAP64024.1 - 2.9 8.2 9.8 2.6 8.3 1.9 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 OAP64024.1 - 5.1 7.3 9.9 11 6.2 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Adaptin_N PF01602.15 OAP64025.1 - 2.5e-113 379.2 0.1 3.4e-113 378.7 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 OAP64025.1 - 8.1e-56 188.0 1.1 1.6e-55 187.0 0.8 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 OAP64025.1 - 1.3e-15 57.4 3.1 1.8e-05 24.9 0.1 6.6 3 1 3 6 6 6 4 HEAT repeats HEAT_PBS PF03130.11 OAP64025.1 - 0.0049 17.2 0.3 4.9 7.9 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat HEAT PF02985.17 OAP64025.1 - 0.0069 16.3 9.7 0.5 10.5 0.1 5.6 7 0 0 7 7 7 1 HEAT repeat CLASP_N PF12348.3 OAP64025.1 - 0.017 14.4 0.4 1 8.6 0.1 2.9 2 0 0 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.1 OAP64025.1 - 0.026 15.0 2.4 0.09 13.2 0.5 2.8 2 0 0 2 2 2 0 HEAT-like repeat DUF3730 PF12530.3 OAP64025.1 - 0.075 12.9 1.0 0.68 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) SPC25 PF06703.6 OAP64026.1 - 1.4e-46 157.9 0.1 1.8e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Fungal_trans PF04082.13 OAP64027.1 - 1.3e-31 109.4 0.2 1.8e-31 108.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64027.1 - 5.3e-08 32.6 9.8 1.1e-07 31.6 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_Glu_race PF01177.17 OAP64028.1 - 4.1e-13 49.7 0.0 5.1e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Transp_cyt_pur PF02133.10 OAP64029.1 - 5.2e-89 298.8 38.2 6.1e-89 298.5 26.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glucan_synthase PF02364.10 OAP64029.1 - 4.6 4.9 6.5 6.9 4.4 4.5 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Aldo_ket_red PF00248.16 OAP64030.1 - 5.7e-45 153.3 0.0 6.4e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAF-AH_p_II PF03403.8 OAP64032.1 - 1.2e-12 46.8 0.0 3.6e-06 25.5 0.0 2.4 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 OAP64032.1 - 1.1e-11 44.6 0.3 2.4e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP64032.1 - 5.3e-06 26.4 0.7 9.8e-06 25.6 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAP64032.1 - 0.019 13.8 0.2 0.35 9.7 0.1 2.6 2 1 0 2 2 2 0 Chlorophyllase enzyme PPV_E2_C PF00511.12 OAP64032.1 - 0.12 12.3 0.4 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 E2 (early) protein, C terminal Peptidase_S28 PF05577.7 OAP64033.1 - 1.3e-40 139.3 0.5 1.5e-40 139.0 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 OAP64033.1 - 3.3e-05 23.2 0.1 5.8e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAP64033.1 - 0.00047 20.1 0.0 0.0007 19.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP64033.1 - 0.026 14.0 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 OAP64034.1 - 0.055 12.0 1.6 0.31 9.6 1.1 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain Beta-lactamase PF00144.19 OAP64035.1 - 2.5e-49 168.1 0.0 3.3e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 OAP64035.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase GFA PF04828.9 OAP64036.1 - 2e-18 66.1 0.1 2.5e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme TFR_dimer PF04253.10 OAP64037.1 - 8.9e-19 67.2 0.0 1.5e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 OAP64037.1 - 4e-16 59.2 0.0 7.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 OAP64037.1 - 1.4e-07 31.0 0.1 6.1e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 OAP64037.1 - 0.007 15.6 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Nicastrin NMO PF03060.10 OAP64038.1 - 2.9e-38 131.8 12.1 6.8e-31 107.6 3.1 2.2 1 1 1 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 OAP64038.1 - 1.6e-06 27.1 0.7 2.3e-06 26.7 0.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 OAP64038.1 - 1.8e-05 23.8 3.8 0.00026 20.0 2.6 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 OAP64038.1 - 0.00094 18.1 1.4 0.0017 17.3 1.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 OAP64038.1 - 0.05 12.8 2.3 0.097 11.9 0.1 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein Pox_G7 PF05503.7 OAP64038.1 - 0.14 10.7 0.1 2.2 6.8 0.0 2.0 2 0 0 2 2 2 0 Poxvirus G7-like DUF561 PF04481.7 OAP64038.1 - 0.16 10.9 1.4 0.28 10.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF561) MFS_1 PF07690.11 OAP64039.1 - 1.5e-38 132.4 15.3 1.5e-25 89.6 3.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP64039.1 - 4.2e-11 42.0 7.5 3e-10 39.2 0.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 OAP64039.1 - 0.0002 19.7 0.2 0.0002 19.7 0.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SpoIIIAH PF12685.2 OAP64039.1 - 0.18 11.3 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Nucleoplasmin PF03066.10 OAP64039.1 - 0.22 11.0 3.1 0.41 10.1 2.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 OAP64039.1 - 0.67 8.6 9.8 0.93 8.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAD_binding_7 PF03441.9 OAP64040.1 - 1.9e-98 329.1 1.6 2.5e-98 328.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAP64040.1 - 2.1e-38 131.6 0.0 4.3e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase HATPase_c PF02518.21 OAP64041.1 - 5.1e-28 97.0 0.0 1.2e-27 95.7 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP64041.1 - 3e-24 85.1 0.1 5.3e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 OAP64041.1 - 2.6e-13 49.7 0.0 6.2e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 OAP64041.1 - 1.9e-05 24.7 2.5 0.11 12.6 0.0 3.4 4 0 0 4 4 4 2 HAMP domain HAMP PF00672.20 OAP64043.1 - 1.2e-45 153.5 21.8 2.4e-08 34.0 0.1 7.5 6 1 1 7 7 7 6 HAMP domain HATPase_c PF02518.21 OAP64043.1 - 1.4e-29 101.9 0.1 6.1e-29 99.9 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP64043.1 - 4.2e-26 91.1 1.8 3.7e-25 88.1 0.2 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 OAP64043.1 - 7.8e-17 61.0 0.3 7.8e-17 61.0 0.2 3.9 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain NAAA-beta PF15508.1 OAP64043.1 - 0.0091 16.3 1.1 14 6.0 0.1 5.8 5 1 1 6 6 6 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase PilJ PF13675.1 OAP64043.1 - 0.047 14.0 11.3 3.8 7.8 0.1 6.6 4 3 2 8 8 8 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2365 PF10157.4 OAP64043.1 - 0.16 11.8 19.4 11 5.8 0.0 7.4 6 2 1 7 7 7 0 Uncharacterized conserved protein (DUF2365) Atg14 PF10186.4 OAP64043.1 - 4.2 6.2 14.4 1.1 8.0 4.3 3.2 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Fungal_trans PF04082.13 OAP64044.1 - 2.2e-19 69.3 0.1 4e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytochrom_B561 PF03188.11 OAP64045.1 - 2.2e-12 46.9 9.4 2.7e-12 46.7 4.6 2.2 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 OAP64045.1 - 3.6e-05 23.6 0.2 6.9e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 OAP64045.1 - 0.00063 19.2 2.5 0.00063 19.2 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) EphA2_TM PF14575.1 OAP64045.1 - 0.0044 17.3 0.1 0.077 13.3 0.0 2.7 3 0 0 3 3 2 1 Ephrin type-A receptor 2 transmembrane domain Sex_peptide PF08138.6 OAP64045.1 - 0.2 11.5 0.9 8.9 6.2 0.0 3.2 3 0 0 3 3 3 0 Sex peptide (SP) family OAD_gamma PF04277.8 OAP64045.1 - 0.25 11.7 4.0 12 6.4 0.0 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Tad PF13400.1 OAP64045.1 - 0.57 10.2 0.1 0.57 10.2 0.0 3.6 4 0 0 4 4 4 0 Putative Flp pilus-assembly TadE/G-like DUF4175 PF13779.1 OAP64045.1 - 0.64 7.6 1.8 0.37 8.4 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF202 PF02656.10 OAP64045.1 - 0.7 10.1 11.8 0.1 12.8 0.5 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF202) RCR PF12273.3 OAP64045.1 - 1.3 9.5 5.0 0.49 10.9 0.1 2.7 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red AzlD PF05437.7 OAP64045.1 - 2.4 8.1 10.8 0.067 13.1 2.0 2.4 2 1 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Tetraspannin PF00335.15 OAP64045.1 - 3.4 6.8 8.5 1.9e+02 1.2 7.2 2.7 2 1 0 2 2 2 0 Tetraspanin family Sugar_tr PF00083.19 OAP64046.1 - 1.7e-83 280.6 24.9 2e-83 280.4 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64046.1 - 1.1e-27 96.6 32.3 1.1e-23 83.5 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP64046.1 - 0.00018 19.8 2.0 0.00033 18.9 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RNase_PH PF01138.16 OAP64047.1 - 2.4e-29 102.2 0.1 6.5e-29 100.9 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 HMG-CoA_red PF00368.13 OAP64048.1 - 2.4e-156 520.1 4.1 3.2e-156 519.6 2.9 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 OAP64048.1 - 3.1e-43 147.1 1.6 5e-43 146.4 1.1 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 OAP64048.1 - 5.2e-14 51.9 3.4 2.1e-06 27.2 0.5 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 OAP64048.1 - 8.8e-06 23.9 3.4 8.8e-06 23.9 2.3 1.6 2 0 0 2 2 2 1 Patched family GIT_SHD PF08518.6 OAP64049.1 - 1.3e-21 75.6 5.6 1.8e-13 49.5 0.5 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Tropomyosin_1 PF12718.2 OAP64049.1 - 0.00081 19.2 19.0 0.11 12.3 3.0 3.0 2 0 0 2 2 2 2 Tropomyosin like PM0188 PF11477.3 OAP64049.1 - 0.016 14.0 0.0 0.037 12.8 0.0 1.5 1 0 0 1 1 1 0 Sialyltransferase PMO188 Baculo_PEP_C PF04513.7 OAP64049.1 - 0.042 13.6 0.2 0.042 13.6 0.1 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-H PF05837.7 OAP64049.1 - 0.42 10.8 25.1 0.19 11.9 5.0 3.9 4 0 0 4 4 4 0 Centromere protein H (CENP-H) Prefoldin_3 PF13758.1 OAP64049.1 - 1.2 8.9 10.3 0.1 12.3 1.2 3.1 3 1 0 3 3 3 0 Prefoldin subunit Syntaxin-6_N PF09177.6 OAP64049.1 - 1.6 9.1 13.4 3.9 7.9 0.1 4.1 4 0 0 4 4 4 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 OAP64049.1 - 4.7 6.9 24.7 3.3 7.4 8.5 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 OAP64049.1 - 5.2 6.4 29.0 0.18 11.2 3.6 3.1 2 1 1 3 3 3 0 Intermediate filament protein DUF4201 PF13870.1 OAP64049.1 - 7.8 5.8 21.8 1.9 7.8 8.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF972 PF06156.8 OAP64049.1 - 8.1 6.8 19.9 4 7.8 1.3 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Pro_isomerase PF00160.16 OAP64050.1 - 2e-40 138.5 0.2 2.5e-40 138.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3176 PF11374.3 OAP64051.1 - 0.0008 19.2 2.2 0.0018 18.0 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Oxysterol_BP PF01237.13 OAP64052.1 - 5.9e-133 442.7 0.0 1.5e-132 441.4 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein Ank PF00023.25 OAP64052.1 - 5.8e-17 60.5 0.5 7.6e-05 22.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 OAP64052.1 - 7.6e-16 58.2 0.0 5.7e-09 36.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAP64052.1 - 2e-15 56.4 1.1 3.5e-09 36.5 0.2 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAP64052.1 - 8.2e-13 48.4 0.0 2e-05 24.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP64052.1 - 1.8e-12 46.1 0.0 0.003 17.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 OAP64052.1 - 3.1e-11 43.3 0.2 6.9e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAP64052.1 - 2.9e-10 40.3 0.3 2.9e-09 37.1 0.2 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 OAP64052.1 - 3.2e-07 30.3 0.5 7.3e-07 29.1 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain ENTH PF01417.15 OAP64053.1 - 1.9e-45 153.7 0.1 2.7e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 OAP64053.1 - 8.3e-05 21.4 0.1 0.00011 21.0 0.0 1.1 1 0 0 1 1 1 1 ANTH domain Sugar_tr PF00083.19 OAP64054.1 - 3.7e-76 256.5 27.2 4.3e-76 256.3 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64054.1 - 3.4e-27 95.0 42.1 7.6e-26 90.6 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 OAP64055.1 - 7e-47 159.9 28.6 8.6e-47 159.6 19.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 OAP64056.1 - 5.7e-10 38.5 0.1 1.3e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64056.1 - 0.012 15.4 2.1 0.012 15.4 1.5 3.1 3 1 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 OAP64059.1 - 2.3e-29 102.3 0.0 9.4e-29 100.3 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRP7 PF12923.2 OAP64060.1 - 1.1e-29 103.1 12.7 1.1e-29 103.1 8.8 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 OAP64060.1 - 0.052 13.1 0.0 8.3 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP12 PF07542.6 OAP64062.1 - 5.5e-38 129.6 0.2 1e-37 128.7 0.2 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein MAS20 PF02064.10 OAP64062.1 - 0.18 11.7 0.7 1.6 8.6 0.1 2.2 1 1 1 2 2 2 0 MAS20 protein import receptor Pmp3 PF01679.12 OAP64063.1 - 7.4e-11 41.5 3.6 9.3e-11 41.2 2.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_9 PF14604.1 OAP64064.1 - 2.6e-11 42.9 0.0 6.3e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAP64064.1 - 3.2e-11 42.4 0.0 5.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAP64064.1 - 1.6e-07 30.6 0.0 2.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.8 OAP64065.1 - 2.6e-82 274.8 0.0 3.1e-82 274.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein NUDIX PF00293.23 OAP64066.1 - 1.5e-13 50.5 0.0 3.9e-12 45.9 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.20 OAP64067.1 - 2.2e-132 441.2 0.7 2.6e-132 441.0 0.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 OAP64067.1 - 5.1e-20 70.9 0.0 7.2e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 OAP64067.1 - 5.6e-08 32.3 1.9 0.0003 20.0 1.5 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 OAP64067.1 - 1.6e-07 30.5 0.9 1.1e-06 27.7 0.5 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 OAP64067.1 - 0.00012 21.4 2.2 0.00042 19.6 1.5 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein DUF1273 PF06908.6 OAP64067.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Aldolase PF01081.14 OAP64067.1 - 0.061 12.4 1.3 0.12 11.4 0.1 2.0 2 0 0 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.9 OAP64067.1 - 0.082 11.9 3.1 0.1 11.6 0.9 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG RasGAP_C PF03836.10 OAP64068.1 - 1.4e-47 160.9 5.2 1.4e-47 160.9 3.6 2.5 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.14 OAP64068.1 - 1.8e-37 128.9 0.0 1.6e-36 125.8 0.0 2.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 OAP64068.1 - 5.7e-12 45.6 0.0 2e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 OAP64068.1 - 0.031 13.9 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain IQ PF00612.22 OAP64068.1 - 0.097 12.3 65.7 0.68 9.7 0.0 13.6 16 0 0 16 16 16 0 IQ calmodulin-binding motif Pkinase PF00069.20 OAP64070.1 - 9.2e-74 247.8 0.0 1.5e-73 247.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP64070.1 - 4.1e-36 124.3 0.0 1e-35 123.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP64070.1 - 5.8e-05 22.1 1.4 0.74 8.7 0.0 3.2 3 0 0 3 3 3 3 Kinase-like APH PF01636.18 OAP64070.1 - 0.00065 19.4 0.0 0.4 10.3 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAP64070.1 - 0.14 10.9 0.1 0.25 10.1 0.0 1.4 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 OAP64071.1 - 4.3e-35 121.0 45.6 4.3e-35 121.0 31.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP64071.1 - 1.8e-12 46.6 42.1 2.7e-08 32.8 11.4 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 OAP64071.1 - 0.0091 15.7 4.2 0.014 15.1 0.4 2.6 2 0 0 2 2 2 1 MFS_1 like family HET PF06985.6 OAP64072.1 - 8.5e-29 100.4 0.0 2.1e-28 99.2 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IDO PF01231.13 OAP64073.1 - 1.3e-35 122.7 0.0 1.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase zf-C2H2_7 PF15269.1 OAP64074.1 - 0.0019 18.0 0.4 0.0037 17.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C2H2_2 PF12756.2 OAP64074.1 - 0.078 13.0 0.1 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF4066 PF13278.1 OAP64075.1 - 1.9e-09 36.9 0.0 3.8e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 Putative amidotransferase DJ-1_PfpI PF01965.19 OAP64075.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF161 PF02588.10 OAP64075.1 - 0.04 14.2 0.1 0.078 13.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 EzrA PF06160.7 OAP64078.1 - 0.0019 16.4 1.3 0.0054 14.9 0.2 2.0 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA IncA PF04156.9 OAP64078.1 - 0.3 10.6 7.8 4.2 6.9 0.3 2.7 2 1 0 2 2 2 0 IncA protein FlgN PF05130.7 OAP64080.1 - 0.031 14.5 10.1 0.23 11.7 2.3 3.2 2 2 2 4 4 4 0 FlgN protein DUF883 PF05957.8 OAP64081.1 - 0.016 15.6 1.8 0.016 15.6 1.2 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-RING_2 PF13639.1 OAP64083.1 - 5.4e-09 35.7 1.8 5.4e-09 35.7 1.3 4.0 3 1 0 3 3 3 1 Ring finger domain PHD PF00628.24 OAP64083.1 - 1.5e-08 34.1 10.5 1.5e-08 34.1 7.3 2.6 2 1 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 OAP64083.1 - 1.4e-05 25.0 0.3 1.4e-05 25.0 0.2 2.6 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAP64083.1 - 1.5e-05 24.5 0.8 1.5e-05 24.5 0.6 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP64083.1 - 2e-05 24.1 0.5 2e-05 24.1 0.4 3.4 4 1 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAP64083.1 - 4.3e-05 23.4 1.3 4.3e-05 23.4 0.9 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP64083.1 - 0.00014 21.4 1.0 0.00014 21.4 0.7 3.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 OAP64083.1 - 0.00048 19.8 5.3 0.0022 17.7 0.7 2.6 1 1 2 3 3 3 2 Double zinc ribbon zf-Apc11 PF12861.2 OAP64083.1 - 0.0074 16.0 0.3 0.0074 16.0 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-PHD-like PF15446.1 OAP64083.1 - 0.076 12.3 5.2 0.032 13.5 1.2 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zinc_ribbon_5 PF13719.1 OAP64083.1 - 0.24 11.0 2.0 6 6.5 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 OAP64083.1 - 0.75 9.5 3.2 5.6 6.7 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_4 PF14447.1 OAP64083.1 - 0.99 8.9 9.5 0.042 13.4 0.6 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 PHD_2 PF13831.1 OAP64083.1 - 2.3 7.6 11.4 0.18 11.1 4.4 1.9 2 0 0 2 2 2 0 PHD-finger zf-P11 PF03854.9 OAP64083.1 - 2.6 7.6 6.6 0.26 10.7 0.8 2.1 2 0 0 2 2 2 0 P-11 zinc finger Ribosomal_L37ae PF01780.14 OAP64084.1 - 2e-40 136.5 10.8 2.2e-40 136.4 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 OAP64084.1 - 0.0027 17.4 2.4 0.0042 16.8 1.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 OAP64084.1 - 0.0066 15.8 4.4 0.49 9.9 0.1 2.1 2 0 0 2 2 2 2 A2L zinc ribbon domain GCC2_GCC3 PF07699.8 OAP64084.1 - 0.022 14.3 0.3 0.033 13.7 0.2 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 zf-BED PF02892.10 OAP64084.1 - 0.08 12.7 5.6 0.74 9.6 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger C1_1 PF00130.17 OAP64084.1 - 0.18 11.5 2.4 0.27 10.9 1.7 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NOB1_Zn_bind PF08772.6 OAP64084.1 - 0.2 11.5 3.2 0.4 10.5 0.2 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-C2H2 PF00096.21 OAP64084.1 - 1.2 9.6 3.7 14 6.2 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Sec23_Sec24 PF04810.10 OAP64084.1 - 1.8 8.1 4.5 1.2 8.7 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger CarbpepA_inh PF02977.10 OAP64084.1 - 9.6 5.8 7.1 4.1 7.0 0.9 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Saccharop_dh PF03435.13 OAP64085.1 - 3.1e-22 79.1 0.1 8.3e-22 77.6 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 OAP64085.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain COG5 PF10392.4 OAP64086.1 - 0.0075 16.2 2.7 0.078 12.9 0.5 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF1216 PF06746.6 OAP64086.1 - 0.19 11.5 7.0 1.1 9.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1216) CAF1 PF04857.15 OAP64087.1 - 3e-47 161.1 0.0 6.1e-47 160.1 0.0 1.5 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 OAP64087.1 - 0.037 13.4 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 3'-5' exonuclease SRP72 PF08492.7 OAP64088.1 - 6.6e-15 55.2 6.9 6.6e-15 55.2 4.8 2.2 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 OAP64088.1 - 5.8e-08 32.9 8.8 0.036 14.3 2.6 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAP64088.1 - 0.00039 20.8 6.9 18 6.2 0.0 6.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP64088.1 - 0.0034 17.2 8.2 0.32 10.9 0.2 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 OAP64088.1 - 0.0058 16.9 1.0 16 6.2 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP64088.1 - 0.0075 16.1 9.8 4.1 7.5 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 OAP64088.1 - 0.011 15.8 4.4 0.18 11.9 0.6 3.9 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DsrC PF04358.8 OAP64088.1 - 0.013 15.6 0.1 0.046 13.9 0.1 1.9 1 0 0 1 1 1 0 DsrC like protein TPR_10 PF13374.1 OAP64088.1 - 0.019 14.8 4.3 19 5.3 0.1 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Inhibitor_I34 PF10466.4 OAP64088.1 - 0.033 14.2 0.9 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 TPR_16 PF13432.1 OAP64088.1 - 0.31 11.7 11.1 3 8.6 2.4 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAP64088.1 - 7.6 7.2 6.3 54 4.5 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1349 PF07081.6 OAP64089.1 - 8.3e-12 44.8 0.0 2.7e-10 39.9 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1349) F-box PF00646.28 OAP64090.1 - 2.9e-07 29.9 1.7 7.6e-07 28.6 1.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP64090.1 - 0.0001 21.9 0.3 0.00023 20.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 OAP64090.1 - 0.00026 20.5 0.8 0.0071 15.9 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 OAP64090.1 - 0.00057 20.4 0.3 0.016 15.8 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAP64090.1 - 0.00094 18.9 0.2 0.26 11.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAP64090.1 - 0.0024 17.7 0.4 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP64090.1 - 0.0036 17.8 1.8 0.024 15.2 0.2 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAP64090.1 - 0.071 12.7 0.3 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ADIP PF11559.3 OAP64091.1 - 8.9e-33 113.3 9.9 8.9e-33 113.3 6.9 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Vac_Fusion PF02346.11 OAP64091.1 - 0.097 12.1 0.7 0.29 10.5 0.5 1.8 1 0 0 1 1 1 0 Chordopoxvirus fusion protein AKNA PF12443.3 OAP64091.1 - 0.25 11.3 8.0 0.25 11.3 1.2 3.0 3 0 0 3 3 3 0 AT-hook-containing transcription factor GrpE PF01025.14 OAP64091.1 - 0.61 9.6 11.2 1.9 7.9 3.3 3.0 2 2 0 2 2 2 0 GrpE Rab5-bind PF09311.6 OAP64091.1 - 1.4 8.7 23.9 11 5.9 16.5 2.2 1 1 0 1 1 1 0 Rabaptin-like protein Atg14 PF10186.4 OAP64091.1 - 3.4 6.5 10.4 1.7 7.4 5.6 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Bacillus_HBL PF05791.6 OAP64091.1 - 3.9 6.8 6.3 2 7.7 1.2 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.10 OAP64091.1 - 9.8 5.7 9.0 3.1 7.3 2.9 2.7 2 1 0 2 2 2 0 Septum formation initiator ADH_N PF08240.7 OAP64092.1 - 1.6e-21 76.0 2.4 3.2e-21 75.1 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP64092.1 - 7.3e-21 74.0 0.0 1.4e-20 73.1 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP64092.1 - 1.3e-07 32.5 0.0 2.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 OAP64092.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAP64092.1 - 0.081 12.0 0.3 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CbiG_mid PF11761.3 OAP64092.1 - 0.17 12.1 0.3 0.8 9.9 0.1 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis central region DUF983 PF06170.7 OAP64092.1 - 0.88 9.7 0.0 0.88 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Nucleopor_Nup85 PF07575.8 OAP64093.1 - 4.8e-19 68.0 0.2 5e-17 61.3 0.0 3.3 2 1 0 2 2 2 1 Nup85 Nucleoporin Zn_clus PF00172.13 OAP64094.1 - 0.00011 21.9 12.6 0.00019 21.2 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP64094.1 - 0.00059 18.7 0.0 0.00059 18.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain TRP PF06011.7 OAP64095.1 - 1.3e-88 297.5 19.3 5.3e-88 295.5 13.3 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 OAP64095.1 - 2.7e-23 82.5 0.1 4.2e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Zn_clus PF00172.13 OAP64096.1 - 0.00013 21.8 10.7 0.00023 21.0 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCMA-Tall_bind PF09257.5 OAP64096.1 - 0.38 10.7 4.9 1.2 9.1 3.4 1.8 1 0 0 1 1 1 0 BCMA, TALL-1 binding Amidase PF01425.16 OAP64097.1 - 3.4e-83 279.9 0.0 4.4e-83 279.5 0.0 1.1 1 0 0 1 1 1 1 Amidase RNB PF00773.14 OAP64098.1 - 3e-25 89.2 0.1 2.5e-18 66.4 0.0 2.3 2 0 0 2 2 2 2 RNB domain SBDS_C PF09377.5 OAP64099.1 - 3.4e-44 149.5 0.1 6.5e-44 148.6 0.0 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 OAP64099.1 - 5.2e-26 90.2 0.0 3.7e-25 87.5 0.0 2.2 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein FliL PF03748.9 OAP64099.1 - 0.076 13.0 1.2 1.2 9.2 0.3 2.3 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL C-term_anchor PF13461.1 OAP64100.1 - 0.17 12.3 1.1 0.53 10.7 0.8 1.9 1 0 0 1 1 1 0 Cell-wall surface anchor repeat SOCS PF12610.3 OAP64100.1 - 0.64 10.3 6.9 1.1 9.6 3.7 2.2 2 0 0 2 2 2 0 Suppressor of cytokine signalling CytochromB561_N PF09786.4 OAP64100.1 - 2.3 6.5 7.5 2.8 6.2 5.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal CDK2AP PF09806.4 OAP64100.1 - 4.5 7.4 11.8 2.1 8.5 6.3 1.8 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein RNA_pol_Rpb2_6 PF00562.23 OAP64102.1 - 4.2e-123 410.9 0.2 6.4e-123 410.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAP64102.1 - 5.3e-49 165.9 0.0 8.3e-49 165.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 OAP64102.1 - 1.8e-35 122.0 0.0 3.5e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAP64102.1 - 3.1e-30 104.2 0.2 1e-29 102.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 OAP64102.1 - 2.3e-22 78.5 0.0 4.5e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 OAP64102.1 - 3.9e-20 71.5 0.4 8.8e-20 70.4 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.8 OAP64102.1 - 3.4e-17 61.9 0.2 8.8e-17 60.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 CTNNBL PF08216.6 OAP64103.1 - 1.3e-33 114.8 0.4 7.2e-33 112.4 0.0 2.4 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 OAP64103.1 - 0.024 14.9 2.6 1.9 8.8 0.0 3.8 3 1 1 4 4 4 0 HEAT repeats Arm PF00514.18 OAP64103.1 - 0.024 14.4 0.1 0.47 10.3 0.1 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Herpes_UL6 PF01763.11 OAP64103.1 - 0.057 11.5 0.3 0.097 10.8 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Arrestin_N PF00339.24 OAP64104.1 - 0.00043 20.1 0.0 0.0026 17.6 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain CDV3 PF15359.1 OAP64104.1 - 0.0079 16.2 0.8 1.5 8.9 0.2 2.5 2 0 0 2 2 2 2 Carnitine deficiency-associated protein 3 WD40 PF00400.27 OAP64105.1 - 2.2e-12 46.3 11.2 1.7e-06 27.6 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 OAP64105.1 - 3.4e-05 22.3 0.0 7.9e-05 21.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain RNA_pol_Rpb1_5 PF04998.12 OAP64106.1 - 2.3e-101 338.7 0.1 4.2e-101 337.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 OAP64106.1 - 3.8e-98 328.8 0.0 9.4e-98 327.5 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 OAP64106.1 - 1.6e-70 236.3 0.0 2.9e-70 235.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 OAP64106.1 - 1.6e-58 197.5 0.4 2.7e-58 196.7 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 OAP64106.1 - 6.2e-45 152.7 0.0 1.2e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 OAP64106.1 - 8.2e-38 129.1 2.3 1.7e-37 128.1 1.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 OAP64106.1 - 1.2e-34 118.3 0.2 3e-34 116.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 OAP64106.1 - 6e-10 38.3 227.5 0.022 14.8 6.4 16.2 9 4 4 16 16 16 12 RNA polymerase Rpb1 C-terminal repeat CGI-121 PF08617.5 OAP64107.1 - 1.6e-38 131.9 0.0 3.8e-38 130.6 0.0 1.6 1 1 0 1 1 1 1 Kinase binding protein CGI-121 DUF3405 PF11885.3 OAP64108.1 - 4.8e-143 476.9 1.5 4.4e-130 434.2 0.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) adh_short PF00106.20 OAP64109.1 - 9.3e-19 67.9 0.3 1.2e-18 67.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64109.1 - 6.7e-11 42.4 0.0 8.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64109.1 - 0.00036 20.2 0.2 0.0006 19.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Viral_protease PF08715.5 OAP64109.1 - 0.0012 18.0 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Papain like viral protease NAD_binding_10 PF13460.1 OAP64109.1 - 0.0023 17.9 0.2 0.005 16.8 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP64109.1 - 0.0081 15.6 0.1 0.012 15.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 OAP64109.1 - 0.027 13.7 0.1 0.058 12.6 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family THF_DHG_CYH_C PF02882.14 OAP64109.1 - 0.091 11.8 0.1 12 4.9 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_FMN PF00724.15 OAP64110.1 - 3.5e-67 226.8 0.0 1.1e-64 218.5 0.0 2.5 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Cu-oxidase_3 PF07732.10 OAP64111.1 - 1e-27 96.2 0.2 3.2e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 OAP64111.1 - 9.5e-26 90.5 0.0 1.7e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP64111.1 - 9.6e-19 67.2 0.9 4.5e-15 55.3 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase MFS_1 PF07690.11 OAP64112.1 - 7.9e-33 113.6 26.9 9.9e-33 113.3 18.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.15 OAP64113.1 - 2.1e-29 102.6 9.6 3.2e-29 102.0 6.7 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 NfeD PF01957.13 OAP64113.1 - 1.2 9.2 5.9 9.1 6.4 0.7 2.4 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Hist_deacetyl PF00850.14 OAP64114.1 - 6e-59 199.8 0.0 7.7e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Clr5 PF14420.1 OAP64115.1 - 6.4e-12 45.1 3.6 1.5e-11 44.0 2.5 1.7 1 0 0 1 1 1 1 Clr5 domain HTH_33 PF13592.1 OAP64115.1 - 0.18 11.3 1.4 0.67 9.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Fungal_trans PF04082.13 OAP64116.1 - 9.2e-21 73.8 0.0 1.1e-19 70.3 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Slx4 PF09494.5 OAP64116.1 - 5.3e-12 45.2 0.1 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease Zn_clus PF00172.13 OAP64116.1 - 0.0014 18.4 6.0 0.0027 17.5 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 OAP64117.1 - 1.5e-08 34.4 10.5 5.8e-08 32.5 7.3 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP64117.1 - 3.6e-06 26.6 8.1 6.4e-06 25.8 5.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_UL6 PF01763.11 OAP64117.1 - 0.00088 17.5 4.6 0.0011 17.2 3.2 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like bZIP_Maf PF03131.12 OAP64117.1 - 0.0073 16.5 7.4 0.015 15.5 5.2 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Spore_III_AF PF09581.5 OAP64117.1 - 0.84 9.4 2.9 1.2 9.0 2.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) NAM-associated PF14303.1 OAP64117.1 - 0.85 9.9 8.2 1.2 9.4 5.7 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain AMP-binding PF00501.23 OAP64118.1 - 1.2e-70 238.0 0.0 1.7e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP64118.1 - 1.5e-09 38.6 0.0 3.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Myb_DNA-bind_6 PF13921.1 OAP64119.1 - 1.9e-10 40.6 2.5 1.2e-06 28.5 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAP64119.1 - 3.9e-10 39.6 4.4 8.3e-06 25.7 0.8 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 OAP64119.1 - 0.14 11.7 0.2 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3084 PF11283.3 OAP64121.1 - 0.028 14.2 0.5 0.054 13.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) p450 PF00067.17 OAP64122.1 - 3.5e-57 193.9 0.0 2.1e-56 191.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 PDR_assoc PF08370.6 OAP64122.1 - 0.17 11.4 2.9 0.36 10.3 2.0 1.4 1 0 0 1 1 1 0 Plant PDR ABC transporter associated adh_short PF00106.20 OAP64123.1 - 1.5e-26 93.3 2.1 2.5e-26 92.5 1.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64123.1 - 1.7e-24 86.8 0.5 2.4e-24 86.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64123.1 - 5.9e-11 42.3 0.4 9.8e-11 41.6 0.2 1.3 1 0 0 1 1 1 1 KR domain GDPD_2 PF13653.1 OAP64123.1 - 0.057 13.6 0.1 8.6 6.6 0.0 3.1 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family DUF3391 PF11871.3 OAP64123.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Abhydrolase_3 PF07859.8 OAP64124.1 - 5.3e-44 150.3 0.0 8.1e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP64124.1 - 2.4e-10 39.7 0.6 1.1e-09 37.5 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 OAP64124.1 - 0.057 12.6 0.2 0.41 9.8 0.2 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Stress-antifung PF01657.12 OAP64125.1 - 0.95 9.8 3.9 0.4 11.0 0.7 1.8 2 0 0 2 2 2 0 Salt stress response/antifungal Glyoxalase_2 PF12681.2 OAP64126.1 - 1.2e-05 25.8 0.1 2.6e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain DUF2205 PF10224.4 OAP64127.1 - 4.7e-25 86.9 1.6 5.3e-25 86.7 1.1 1.0 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Myosin_tail_1 PF01576.14 OAP64127.1 - 0.00033 18.5 2.7 0.00033 18.5 1.9 1.0 1 0 0 1 1 1 1 Myosin tail DUF4201 PF13870.1 OAP64127.1 - 0.0015 17.9 0.7 0.0018 17.7 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF972 PF06156.8 OAP64127.1 - 0.0031 17.8 0.5 0.0036 17.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 OAP64127.1 - 0.0076 16.1 0.9 0.18 11.7 0.1 2.2 1 1 1 2 2 2 1 TSC-22/dip/bun family CASP_C PF08172.7 OAP64127.1 - 0.0085 15.1 1.0 0.0086 15.1 0.7 1.1 1 0 0 1 1 1 1 CASP C terminal ADIP PF11559.3 OAP64127.1 - 0.011 15.5 1.3 0.012 15.4 0.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4631 PF15450.1 OAP64127.1 - 0.014 13.7 1.2 0.016 13.5 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) Snapin_Pallidin PF14712.1 OAP64127.1 - 0.03 14.6 0.2 0.036 14.3 0.2 1.2 1 0 0 1 1 1 0 Snapin/Pallidin HOOK PF05622.7 OAP64127.1 - 0.031 12.1 1.7 0.03 12.1 1.2 1.0 1 0 0 1 1 1 0 HOOK protein P4Ha_N PF08336.6 OAP64127.1 - 0.034 13.9 0.4 0.04 13.7 0.2 1.1 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4200 PF13863.1 OAP64127.1 - 0.034 14.0 0.5 0.045 13.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 OAP64127.1 - 0.038 13.8 0.2 0.046 13.5 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HrpB7 PF09486.5 OAP64127.1 - 0.04 13.8 0.7 0.045 13.6 0.5 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Cluap1 PF10234.4 OAP64127.1 - 0.04 13.1 0.2 0.046 12.9 0.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Prefoldin PF02996.12 OAP64127.1 - 0.045 13.4 0.6 0.18 11.4 0.1 1.7 1 1 0 1 1 1 0 Prefoldin subunit IFT20 PF14931.1 OAP64127.1 - 0.048 13.5 0.7 0.059 13.2 0.5 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Syntaxin PF00804.20 OAP64127.1 - 0.059 13.5 0.9 0.079 13.1 0.5 1.5 1 1 0 1 1 1 0 Syntaxin DegS PF05384.6 OAP64127.1 - 0.062 12.5 0.4 0.073 12.2 0.3 1.2 1 0 0 1 1 1 0 Sensor protein DegS Sas10_Utp3 PF04000.10 OAP64127.1 - 0.077 13.1 0.2 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Spc7 PF08317.6 OAP64127.1 - 0.085 11.5 0.9 0.085 11.4 0.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.13 OAP64127.1 - 0.1 12.3 3.3 3 7.6 0.2 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 OAP64127.1 - 0.11 12.0 0.8 0.12 11.9 0.6 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 OAP64127.1 - 0.11 11.9 1.7 0.27 10.7 1.0 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF4446 PF14584.1 OAP64127.1 - 0.15 11.8 0.5 0.18 11.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Sugar_tr PF00083.19 OAP64129.1 - 4.8e-114 381.4 31.5 7.2e-114 380.8 21.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64129.1 - 1.4e-23 83.1 70.1 2.1e-21 76.0 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP64129.1 - 0.00056 18.4 35.5 0.0024 16.3 6.2 3.4 3 1 0 3 3 3 2 MFS/sugar transport protein Glyco_hydro_3 PF00933.16 OAP64130.1 - 2.5e-62 210.5 0.0 3.3e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAP64130.1 - 1.7e-35 122.6 0.2 3.3e-35 121.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 OAP64130.1 - 2.6e-05 24.0 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_tranf_2_3 PF13641.1 OAP64132.1 - 9.2e-28 97.5 0.0 1.4e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAP64132.1 - 1e-11 44.4 0.0 5.8e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAP64132.1 - 2.4e-11 43.6 0.0 4.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_hydro_18 PF00704.23 OAP64134.1 - 1.3e-16 60.9 0.0 1.3e-15 57.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 HSP20 PF00011.16 OAP64135.1 - 2.2e-08 33.8 0.2 4.7e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family p450 PF00067.17 OAP64136.1 - 9.2e-43 146.4 0.0 1.1e-41 142.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 OAP64138.1 - 1.9e-10 40.0 0.0 3.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64138.1 - 5.2e-05 23.0 10.2 0.0001 22.1 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NRDE-2 PF08424.5 OAP64139.1 - 8.4e-74 248.3 1.7 2e-73 247.0 0.4 2.3 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference BP28CT PF08146.7 OAP64139.1 - 2.7e-27 95.3 0.1 1.5e-26 92.9 0.0 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 OAP64139.1 - 1.3e-14 54.2 6.8 4.5e-14 52.4 0.1 4.2 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.1 OAP64139.1 - 0.012 16.0 9.8 1.3 9.5 0.0 6.7 6 0 0 6 6 6 0 HEAT-like repeat HEAT PF02985.17 OAP64139.1 - 0.014 15.4 0.1 0.014 15.4 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat Piwi PF02171.12 OAP64140.1 - 1.2e-49 168.9 0.0 2.1e-49 168.1 0.0 1.4 1 0 0 1 1 1 1 Piwi domain RtcR PF06956.6 OAP64140.1 - 0.032 13.5 0.0 0.084 12.1 0.0 1.6 2 0 0 2 2 2 0 Regulator of RNA terminal phosphate cyclase Polyketide_cyc2 PF10604.4 OAP64141.1 - 3.6e-13 49.8 1.0 4.5e-13 49.5 0.7 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 OAP64141.1 - 2.4e-06 27.5 1.4 2.8e-06 27.3 1.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HEAT PF02985.17 OAP64142.1 - 1.1e-08 34.3 1.5 0.1 12.7 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 OAP64142.1 - 7.8e-05 22.8 7.0 0.00048 20.3 0.2 4.8 4 2 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 OAP64142.1 - 0.00025 21.4 6.3 0.07 13.6 0.1 4.5 4 0 0 4 4 4 2 HEAT-like repeat Cohesin_HEAT PF12765.2 OAP64142.1 - 0.034 14.1 0.1 0.51 10.3 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 OAP64142.1 - 0.15 10.3 0.0 6 5.0 0.0 2.7 2 0 0 2 2 2 0 Adaptin N terminal region DUF1349 PF07081.6 OAP64143.1 - 1.1e-21 76.9 0.0 1.4e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Abhydrolase_1 PF00561.15 OAP64144.1 - 5.5e-13 49.0 0.2 1.2e-12 47.9 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP64144.1 - 9.9e-10 38.6 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP64144.1 - 0.11 12.2 0.6 1.6 8.4 0.4 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Flavin_Reduct PF01613.13 OAP64145.1 - 2e-15 56.9 0.0 3.2e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain SSF PF00474.12 OAP64146.1 - 8.7e-08 31.2 27.8 1.2e-06 27.4 19.3 2.4 1 1 0 1 1 1 1 Sodium:solute symporter family DUF872 PF05915.7 OAP64146.1 - 0.79 9.5 4.2 3.6 7.4 0.2 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4611 PF15387.1 OAP64147.1 - 0.026 14.6 2.9 0.1 12.7 2.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CAP59_mtransfer PF11735.3 OAP64148.1 - 8.3e-76 254.4 0.0 1.1e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 NmrA PF05368.8 OAP64149.1 - 2.2e-09 36.9 0.0 2.2e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NmrA PF05368.8 OAP64150.1 - 9.1e-16 57.8 0.0 1.1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP64150.1 - 4.8e-05 23.4 0.0 5.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP64150.1 - 0.011 14.5 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAP64150.1 - 0.023 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 OAP64150.1 - 0.065 12.6 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAP64150.1 - 0.069 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NMT PF01233.14 OAP64150.1 - 0.096 12.3 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF155 PF02582.9 OAP64151.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Pro_CA PF00484.14 OAP64152.1 - 2.3e-19 69.8 0.0 3.3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase PAP_central PF04928.12 OAP64153.1 - 1.9e-97 325.0 0.0 2.7e-97 324.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 OAP64153.1 - 1.1e-33 116.0 0.0 2.1e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 OAP64153.1 - 5.6e-07 29.8 0.1 1.5e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain HTH_IclR PF09339.5 OAP64153.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF2235 PF09994.4 OAP64154.1 - 2.6e-69 233.6 0.0 3.9e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Amidase PF01425.16 OAP64155.1 - 1.8e-86 290.7 0.0 2.2e-86 290.4 0.0 1.1 1 0 0 1 1 1 1 Amidase PAF-AH_p_II PF03403.8 OAP64156.1 - 5.4e-57 192.8 0.0 1.7e-52 177.9 0.0 2.9 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 OAP64156.1 - 1.6e-09 37.6 0.0 4.9e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP64156.1 - 2e-08 34.4 0.1 5.6e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAP64156.1 - 1.9e-05 23.7 0.0 0.00013 20.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 OAP64156.1 - 0.00067 18.5 0.0 0.0023 16.7 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 OAP64156.1 - 0.0087 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase FAA_hydrolase PF01557.13 OAP64157.1 - 1.6e-41 142.1 0.0 2.9e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 OAP64157.1 - 2.6e-22 78.8 0.0 4.4e-21 74.8 0.0 2.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Glyco_hydro_76 PF03663.9 OAP64158.1 - 1.5e-21 77.1 0.5 1e-18 67.8 0.0 3.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 Aldo_ket_red PF00248.16 OAP64159.1 - 1.7e-57 194.4 0.0 2e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-bind_6 PF13921.1 OAP64160.1 - 0.0011 18.9 0.2 0.002 18.1 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ER_lumen_recept PF00810.13 OAP64161.1 - 4.4e-38 131.0 9.5 6.8e-38 130.4 6.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 OAP64161.1 - 0.0047 16.4 8.6 0.021 14.3 0.0 3.2 3 1 0 3 3 3 2 PQ loop repeat Pox_A51 PF04948.8 OAP64161.1 - 0.11 11.1 1.4 0.14 10.7 0.9 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein Aldo_ket_red PF00248.16 OAP64162.1 - 5.1e-47 160.0 0.0 6.7e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 7TM_GPCR_Sra PF02117.11 OAP64163.1 - 0.026 13.1 0.2 0.044 12.3 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra DUF3623 PF12291.3 OAP64163.1 - 0.049 12.6 0.7 0.087 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) DUF4229 PF14012.1 OAP64163.1 - 8.1 6.4 8.4 1.6 8.7 3.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) SOCS PF12610.3 OAP64164.1 - 0.88 9.9 3.3 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 Suppressor of cytokine signalling COX5B PF01215.14 OAP64165.1 - 1e-32 112.6 0.0 1.4e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CCCH PF00642.19 OAP64166.1 - 7.6e-09 35.0 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 OAP64166.1 - 1.5e-05 24.7 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP64166.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP64166.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2721 PF11026.3 OAP64167.1 - 0.0011 18.6 0.1 0.0013 18.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Mid2 PF04478.7 OAP64167.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2116 PF09889.4 OAP64167.1 - 0.017 14.8 0.3 0.025 14.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF912 PF06024.7 OAP64167.1 - 0.035 14.1 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3976 PF13121.1 OAP64167.1 - 0.047 13.5 3.2 0.072 12.9 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) GRA6 PF05084.8 OAP64167.1 - 0.098 12.1 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Herpes_gE PF02480.11 OAP64167.1 - 0.11 10.7 0.0 0.12 10.6 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 OAP64167.1 - 0.12 12.0 2.6 0.11 12.1 1.1 1.5 2 0 0 2 2 2 0 Syndecan domain DUF4448 PF14610.1 OAP64167.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_US9 PF06072.6 OAP64167.1 - 0.18 11.6 1.5 0.34 10.7 1.1 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF3040 PF11239.3 OAP64167.1 - 0.22 11.5 1.4 0.27 11.3 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) OapA_N PF08525.6 OAP64167.1 - 1.7 8.4 5.5 4.1 7.2 3.8 1.8 1 1 0 1 1 1 0 Opacity-associated protein A N-terminal motif An_peroxidase PF03098.10 OAP64169.1 - 2.4e-122 409.0 0.0 2.7e-122 408.8 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Peroxidase_2 PF01328.12 OAP64170.1 - 7.5e-19 67.5 0.0 1.1e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Aminotran_3 PF00202.16 OAP64171.1 - 7.9e-109 363.5 0.0 9.4e-109 363.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 OAP64171.1 - 0.0017 17.3 0.0 0.0089 15.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II DUF3301 PF11743.3 OAP64171.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) MFS_1 PF07690.11 OAP64172.1 - 2e-18 66.2 47.9 2e-18 66.2 33.2 2.8 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP64172.1 - 4.9e-18 64.6 21.9 6.6e-18 64.2 15.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GP41 PF00517.12 OAP64172.1 - 0.014 15.0 1.1 0.44 10.0 0.0 2.7 3 0 0 3 3 3 0 Retroviral envelope protein DUF4017 PF13209.1 OAP64172.1 - 0.46 10.3 5.9 0.28 11.0 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) ESSS PF10183.4 OAP64172.1 - 3.1 8.2 6.5 31 5.0 0.0 3.7 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) 4HBT PF03061.17 OAP64174.1 - 8.6e-10 38.6 0.1 1.2e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 OAP64174.1 - 5.2e-07 29.6 0.0 6.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.1 OAP64174.1 - 0.06 13.8 0.0 0.066 13.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Cys_Met_Meta_PP PF01053.15 OAP64176.1 - 6.4e-61 205.7 0.0 1.6e-60 204.4 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 OAP64176.1 - 0.0045 15.7 0.0 0.0085 14.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAP64176.1 - 0.02 13.8 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Phage_holin_3 PF05106.7 OAP64176.1 - 0.11 12.5 0.0 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) RdRP PF05183.7 OAP64177.1 - 6.1e-162 540.3 0.0 8.4e-162 539.8 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase GMC_oxred_N PF00732.14 OAP64178.1 - 2.1e-55 187.9 0.0 2.8e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP64178.1 - 6.3e-33 114.0 0.1 1.2e-32 113.1 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAP64178.1 - 0.00017 20.6 3.0 0.0013 17.7 2.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP64178.1 - 0.00017 20.6 3.3 0.0033 16.3 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP64178.1 - 0.00027 19.9 0.4 0.0021 17.0 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP64178.1 - 0.00045 20.1 0.7 0.0012 18.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lactamase_B PF00753.22 OAP64179.1 - 2.9e-09 36.8 2.4 4.5e-09 36.2 1.7 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP64179.1 - 0.00018 21.0 0.4 0.00029 20.4 0.3 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 OAP64180.1 - 9.1e-06 24.7 0.1 1.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 OAP64180.1 - 0.00043 20.4 0.6 0.0046 17.2 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP64180.1 - 0.017 15.4 0.7 0.12 12.7 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type adh_short_C2 PF13561.1 OAP64181.1 - 2.7e-28 99.3 0.0 3.2e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP64181.1 - 3.2e-21 75.9 0.0 3.9e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 OAP64181.1 - 0.00034 20.1 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 OAP64181.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP64181.1 - 0.059 13.3 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAP64181.1 - 0.08 11.8 0.1 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 OAP64181.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.19 OAP64182.1 - 2.5e-79 266.9 25.7 2.9e-79 266.7 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64182.1 - 5.5e-24 84.5 36.8 1.1e-18 67.1 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MerR-DNA-bind PF09278.6 OAP64182.1 - 0.062 13.6 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 MerR, DNA binding DUF4387 PF14330.1 OAP64183.1 - 7.2e-33 112.8 0.0 1.2e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 OAP64183.1 - 6.5e-23 80.7 0.0 5.6e-22 77.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Aldedh PF00171.17 OAP64184.1 - 8.7e-151 502.3 0.4 9.8e-151 502.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HpaB PF03241.8 OAP64184.1 - 0.016 14.0 0.0 3.5 6.4 0.0 3.0 3 0 0 3 3 3 0 4-hydroxyphenylacetate 3-hydroxylase C terminal adh_short_C2 PF13561.1 OAP64185.1 - 3.2e-34 118.7 0.1 3.7e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP64185.1 - 1.6e-26 93.2 2.4 2.6e-26 92.5 1.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP64185.1 - 9.4e-14 51.4 0.7 1.3e-13 50.9 0.5 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 OAP64185.1 - 0.00018 20.3 0.1 0.00082 18.1 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family EpuA PF11772.3 OAP64185.1 - 0.15 11.5 0.1 0.34 10.3 0.1 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Fungal_trans PF04082.13 OAP64186.1 - 1.7e-15 56.5 0.0 2.7e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ProSAAS PF07259.7 OAP64186.1 - 0.11 12.0 3.1 0.14 11.7 0.2 2.4 2 1 1 3 3 3 0 ProSAAS precursor Fungal_trans PF04082.13 OAP64187.1 - 1.9e-07 30.1 0.2 4e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 OAP64188.1 - 3e-91 306.2 30.8 3.4e-91 306.0 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64188.1 - 2.2e-23 82.5 59.8 1.1e-20 73.7 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 OAP64189.1 - 4.2e-20 72.6 0.0 1.9e-19 70.5 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP64189.1 - 8.8e-17 60.4 0.0 1.2e-14 53.3 0.0 3.4 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP64189.1 - 2.9e-11 43.2 0.1 1.5e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP64189.1 - 2.7e-08 33.1 0.0 3e-05 23.1 0.0 3.6 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP64189.1 - 1.7e-05 24.6 0.2 0.00077 19.2 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP64189.1 - 0.00012 22.0 0.0 0.00046 20.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP64189.1 - 0.0028 16.6 0.1 0.74 8.6 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP64189.1 - 0.063 11.7 0.3 0.36 9.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_3_C PF01915.17 OAP64189.1 - 0.12 11.8 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Thi4 PF01946.12 OAP64189.1 - 0.17 10.9 0.1 1.8 7.6 0.0 2.4 3 0 0 3 3 3 0 Thi4 family PEP_mutase PF13714.1 OAP64190.1 - 3.2e-48 164.0 1.9 3.7e-48 163.8 1.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 OAP64190.1 - 1.8e-20 72.6 0.2 2.8e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 Isocitrate lyase family WSN PF02206.13 OAP64191.1 - 0.055 13.2 0.2 0.1 12.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function CobU PF02283.11 OAP64192.1 - 0.086 12.2 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TMEM51 PF15345.1 OAP64192.1 - 1 9.0 5.0 11 5.6 3.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 CitMHS PF03600.11 OAP64193.1 - 0.074 11.6 3.2 0.11 11.0 2.2 1.3 1 0 0 1 1 1 0 Citrate transporter RTA1 PF04479.8 OAP64193.1 - 0.23 10.9 5.3 0.49 9.8 3.7 1.7 1 1 0 1 1 1 0 RTA1 like protein ADH_zinc_N PF00107.21 OAP64196.1 - 3e-06 26.8 0.1 5.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP64196.1 - 9.2e-06 25.3 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pectate_lyase_3 PF12708.2 OAP64197.1 - 1.1e-88 297.1 18.7 5.7e-69 232.6 7.5 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 OAP64197.1 - 4.3e-09 35.7 1.6 0.0013 18.1 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.16 OAP64198.1 - 2.5e-21 76.0 0.0 3.2e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 OAP64198.1 - 0.061 11.8 0.0 0.16 10.5 0.0 1.6 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase AMP-binding PF00501.23 OAP64200.1 - 1e-57 195.4 0.0 1.3e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP64200.1 - 2.5e-12 47.5 1.1 4.6e-12 46.7 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CDC24 PF06395.6 OAP64200.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin Zn_clus PF00172.13 OAP64202.1 - 1e-07 31.7 10.4 2.1e-07 30.7 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 OAP64202.1 - 0.091 12.7 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PARP PF00644.15 OAP64203.1 - 6.9e-31 107.2 0.0 1.8e-30 105.9 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain ADH_zinc_N PF00107.21 OAP64203.1 - 2.1e-09 36.9 0.3 4e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WGR PF05406.10 OAP64203.1 - 2e-07 30.8 0.1 3.9e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 WGR domain ADH_N PF08240.7 OAP64203.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 OAP64204.1 - 6e-77 259.1 0.0 7.3e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TrkA_N PF02254.13 OAP64204.1 - 0.035 14.1 0.1 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.19 OAP64205.1 - 2.1e-60 204.5 25.2 1.8e-59 201.5 14.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP64205.1 - 2.1e-22 79.3 41.8 2.5e-22 79.0 27.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 OAP64206.1 - 1.3e-26 93.9 0.0 3.7e-26 92.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP64206.1 - 3.1e-18 65.3 0.0 1.2e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP64206.1 - 9.6e-10 37.8 0.1 1.8e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAP64206.1 - 2.2e-06 27.6 0.0 7e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP64206.1 - 5e-06 26.5 0.0 0.00013 21.9 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP64206.1 - 1e-05 25.3 3.6 0.00041 20.1 0.2 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 OAP64206.1 - 0.0001 21.3 0.5 0.063 12.1 0.1 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 OAP64206.1 - 0.0056 15.8 0.4 0.033 13.2 0.0 2.5 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.14 OAP64206.1 - 0.17 11.0 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.13 OAP64208.1 - 5.8e-20 71.2 2.2 5.8e-20 71.2 1.5 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 OAP64209.1 - 6.1e-21 75.4 0.0 1.3e-20 74.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP64209.1 - 5e-11 41.5 0.5 6.5e-10 37.8 0.1 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP64209.1 - 1.9e-09 37.3 0.0 4.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAP64209.1 - 3.3e-05 23.7 0.3 0.002 17.9 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAP64209.1 - 0.00023 20.2 0.2 0.11 11.4 0.0 3.8 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP64209.1 - 0.025 14.4 0.0 0.59 9.9 0.0 2.5 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP64209.1 - 0.066 12.3 0.3 0.17 10.9 0.1 1.7 2 0 0 2 2 2 0 Thi4 family AMP-binding PF00501.23 OAP64210.1 - 2.8e-79 266.4 0.0 3.3e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP64210.1 - 1.1e-10 42.3 0.2 6.4e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Beta-lactamase PF00144.19 OAP64211.1 - 1.5e-39 135.9 0.3 2.5e-39 135.2 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase Cyclase PF04199.8 OAP64212.1 - 2.9e-15 56.3 1.4 7.5e-15 55.0 0.9 1.6 1 1 0 1 1 1 1 Putative cyclase Acyl-CoA_dh_1 PF00441.19 OAP64213.1 - 3.9e-25 88.6 0.3 5.5e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP64213.1 - 1.2e-19 69.5 1.0 2.2e-19 68.7 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAP64213.1 - 3.1e-18 66.3 0.1 1.2e-17 64.5 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAP64213.1 - 0.012 15.8 0.1 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.20 OAP64214.1 - 7e-29 100.8 0.1 8.1e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP64214.1 - 1.8e-15 57.0 0.1 2.5e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP64214.1 - 2.1e-09 37.5 0.0 2.4e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAP64214.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 OAP64214.1 - 0.016 14.8 0.6 0.18 11.4 0.2 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAP64214.1 - 0.033 14.2 0.0 0.077 13.1 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 OAP64215.1 - 1.3e-17 63.5 0.7 1.9e-17 62.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 OAP64216.1 - 8.4e-31 107.1 3.8 1.1e-30 106.7 1.9 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64216.1 - 5.5e-28 98.3 0.0 6.4e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64216.1 - 5.1e-12 45.8 1.1 9e-12 45.0 0.7 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP64216.1 - 0.0052 16.2 0.4 0.031 13.7 0.3 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP64216.1 - 0.02 14.8 0.3 0.031 14.2 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 OAP64216.1 - 0.025 13.2 0.2 0.092 11.4 0.1 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1533 PF07550.6 OAP64216.1 - 0.092 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) 3HCDH_N PF02737.13 OAP64216.1 - 0.29 10.7 1.2 0.42 10.2 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 OAP64217.1 - 5.5e-18 65.4 0.9 3e-16 59.7 0.6 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64217.1 - 2.3e-16 60.2 0.6 8.2e-16 58.5 0.4 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64217.1 - 3.9e-06 26.6 0.6 1.8e-05 24.4 0.2 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 OAP64217.1 - 0.052 12.4 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.16 OAP64217.1 - 0.25 11.1 2.5 0.77 9.5 1.3 2.1 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.14 OAP64218.1 - 2.3e-63 214.4 0.0 2.9e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP64218.1 - 0.01 15.7 0.0 0.032 14.0 0.0 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_8 PF13621.1 OAP64219.1 - 6.2e-47 160.2 0.0 9.8e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 OAP64219.1 - 0.08 12.1 0.1 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein HAD_2 PF13419.1 OAP64220.1 - 5.2e-23 82.1 0.0 7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP64220.1 - 7.3e-13 49.4 0.0 3.8e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP64220.1 - 6.9e-09 35.3 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 OAP64220.1 - 0.00016 21.8 0.0 0.00022 21.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 OAP64220.1 - 0.0047 16.8 0.0 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 OAP64220.1 - 0.038 13.6 0.0 3.1 7.4 0.1 2.2 1 1 0 2 2 2 0 NLI interacting factor-like phosphatase SAP18 PF06487.7 OAP64221.1 - 1.3e-38 131.4 0.0 1.7e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) HTH_20 PF12840.2 OAP64222.1 - 0.043 13.6 0.1 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Lactonase PF10282.4 OAP64223.1 - 3.1e-26 92.2 0.1 2.2e-25 89.4 0.0 2.0 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 OAP64223.1 - 0.00091 18.6 0.0 0.014 14.7 0.0 2.5 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Nitroreductase PF00881.19 OAP64224.1 - 2.8e-14 53.2 0.0 3.2e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.11 OAP64225.1 - 1.8e-45 155.1 45.1 9.6e-45 152.8 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP64225.1 - 3.7e-12 45.5 25.2 9e-11 41.0 18.5 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAP64225.1 - 8.1e-05 21.0 4.8 0.00015 20.1 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP64226.1 - 2.3e-06 26.5 29.1 0.00028 19.7 18.2 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily WW PF00397.21 OAP64227.1 - 0.00014 21.6 1.5 0.00039 20.2 1.0 1.9 1 0 0 1 1 1 1 WW domain Gly-zipper_OmpA PF13436.1 OAP64227.1 - 0.12 12.0 0.2 0.12 12.0 0.2 2.2 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Trp_oprn_chp PF09534.5 OAP64227.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MIP-T3 PF10243.4 OAP64228.1 - 0.37 9.2 27.6 0.61 8.4 19.1 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RNA_polI_A34 PF08208.6 OAP64228.1 - 1.1 8.8 35.9 1.9 8.1 24.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.7 OAP64228.1 - 1.2 8.9 18.0 2.3 8.0 12.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 OAP64228.1 - 1.6 8.0 20.2 3 7.1 14.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 OAP64228.1 - 2.1 8.2 13.6 3.2 7.6 9.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 OAP64228.1 - 2.5 7.2 20.5 5.6 6.0 14.2 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) NARP1 PF12569.3 OAP64228.1 - 6.6 5.3 21.7 9.2 4.8 15.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sugar_tr PF00083.19 OAP64229.1 - 5.4e-75 252.6 33.1 6.5e-75 252.4 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64229.1 - 2.4e-28 98.8 52.5 3.1e-25 88.6 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.1 OAP64230.1 - 6.7e-14 51.8 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAP64230.1 - 5.7e-09 36.3 0.0 1.2e-08 35.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP64230.1 - 2.8e-06 27.2 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP64230.1 - 0.00099 18.9 0.1 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2347 PF09804.4 OAP64231.1 - 1.6e-95 319.6 0.0 3.6e-95 318.4 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 OAP64231.1 - 3.5e-44 150.9 4.1 8.4e-44 149.7 2.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 OAP64231.1 - 3.4e-06 25.7 0.6 0.023 13.1 0.0 2.8 3 0 0 3 3 3 2 Transport protein Avl9 SPA PF08616.5 OAP64231.1 - 0.0002 21.0 0.0 0.00044 19.9 0.0 1.5 1 1 0 1 1 1 1 Stabilization of polarity axis Abhydrolase_6 PF12697.2 OAP64233.1 - 3.7e-15 56.4 1.7 6e-15 55.7 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP64233.1 - 4.1e-13 49.3 0.1 9.2e-13 48.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAP64233.1 - 1.4e-07 31.3 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 OAP64233.1 - 0.0078 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAP64233.1 - 0.014 15.1 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 OAP64233.1 - 0.017 14.5 0.1 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 OAP64233.1 - 0.04 13.1 0.0 0.18 10.9 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Glyco_trans_4_4 PF13579.1 OAP64233.1 - 0.89 9.6 5.2 2.9 8.0 1.4 2.8 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain ADH_N PF08240.7 OAP64234.1 - 1.3e-23 82.8 3.2 2.5e-23 81.8 2.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP64234.1 - 1.7e-09 37.2 0.0 3.6e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAP64234.1 - 0.00028 20.1 0.1 0.001 18.2 0.0 1.8 1 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 OAP64234.1 - 0.00049 19.6 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PAN_1 PF00024.21 OAP64235.1 - 0.00061 19.4 0.7 0.00061 19.4 0.5 3.2 3 1 0 3 3 3 1 PAN domain PAN_4 PF14295.1 OAP64235.1 - 0.017 14.8 1.9 0.017 14.8 1.3 2.7 3 0 0 3 3 3 0 PAN domain SOG2 PF10428.4 OAP64235.1 - 4.6 5.7 19.1 5.8 5.4 13.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SNF2_N PF00176.18 OAP64236.1 - 2.5e-65 220.2 0.0 6.2e-65 218.9 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP64236.1 - 4.1e-10 39.3 0.0 9.8e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP64236.1 - 2.1e-07 30.9 0.0 8.3e-07 29.0 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 OAP64236.1 - 0.039 12.9 0.0 0.081 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PP2C_C PF07830.8 OAP64237.1 - 3 7.9 6.4 0.73 9.9 0.9 2.6 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF904 PF06005.7 OAP64238.1 - 0.087 13.1 1.0 0.41 10.9 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) FAD_binding_3 PF01494.14 OAP64239.1 - 4.7e-12 45.6 3.5 7.1e-12 45.0 0.3 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 OAP64239.1 - 1.7e-05 24.6 0.7 0.067 12.9 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.5 OAP64239.1 - 3e-05 22.9 0.0 0.00058 18.7 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.19 OAP64239.1 - 0.00072 18.7 0.0 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 OAP64239.1 - 0.0012 17.7 0.2 0.52 9.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase M20_dimer PF07687.9 OAP64239.1 - 0.13 11.9 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Peptidase dimerisation domain Macro PF01661.16 OAP64241.1 - 1.8e-11 43.9 0.0 1.2e-08 34.8 0.0 2.6 1 1 0 1 1 1 1 Macro domain MIF PF01187.13 OAP64241.1 - 4.7e-11 42.7 0.0 8.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DnaJ PF00226.26 OAP64241.1 - 0.083 12.6 1.0 0.33 10.7 0.1 2.4 2 1 0 2 2 2 0 DnaJ domain TruD PF01142.13 OAP64242.1 - 2.6e-50 171.2 0.0 4.9e-46 157.1 0.0 3.9 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) DUF2370 PF10176.4 OAP64245.1 - 0.12 11.6 0.4 0.21 10.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Kinocilin PF15033.1 OAP64245.1 - 1.9 8.0 3.8 0.44 10.0 0.1 1.8 2 0 0 2 2 2 0 Kinocilin protein Bac_luciferase PF00296.15 OAP64248.1 - 0.02 13.9 0.0 0.023 13.8 0.0 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF4448 PF14610.1 OAP64250.1 - 6.7e-05 22.4 0.1 0.00014 21.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 OAP64250.1 - 0.0005 19.3 2.4 0.0013 18.0 1.7 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 OAP64250.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family MFS_1 PF07690.11 OAP64251.1 - 3e-39 134.7 29.4 3e-39 134.7 20.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP64251.1 - 9.9e-10 37.5 24.0 1.4e-09 37.0 16.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter VPS28 PF03997.7 OAP64252.1 - 8.5e-57 191.8 0.2 1e-56 191.5 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Imm3 PF14425.1 OAP64252.1 - 0.0065 16.4 0.4 0.59 10.1 0.1 2.4 2 0 0 2 2 2 2 Immunity protein Imm3 GvpG PF05120.7 OAP64252.1 - 0.37 10.6 2.2 1.3 8.8 0.2 2.1 2 0 0 2 2 2 0 Gas vesicle protein G Noc2 PF03715.8 OAP64253.1 - 1.2e-118 395.3 0.2 3.1e-118 394.0 0.1 1.7 1 0 0 1 1 1 1 Noc2p family Glycos_transf_1 PF00534.15 OAP64254.1 - 8e-19 67.6 0.0 2.1e-18 66.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAP64254.1 - 1.1e-07 32.0 0.0 3.8e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 OAP64254.1 - 6.7e-05 23.0 0.1 0.00018 21.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 GARS_C PF02843.11 OAP64255.1 - 0.087 13.0 0.4 0.18 12.0 0.3 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain DUF2570 PF10828.3 OAP64255.1 - 0.69 9.5 2.9 1.7 8.3 2.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) FUSC PF04632.7 OAP64255.1 - 2.3 6.5 4.2 3 6.1 2.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3328 PF11807.3 OAP64256.1 - 1e-22 80.9 0.3 1e-22 80.9 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) YL1_C PF08265.6 OAP64257.1 - 0.0059 16.1 18.4 44 3.7 0.1 7.6 4 1 7 11 11 11 7 YL1 nuclear protein C-terminal domain DIM PF08194.7 OAP64257.1 - 0.026 14.4 1.3 0.037 13.9 0.9 1.2 1 0 0 1 1 1 0 DIM protein CABS1 PF15367.1 OAP64257.1 - 0.73 8.6 8.1 3.8 6.2 1.1 2.7 1 1 3 4 4 4 0 Calcium-binding and spermatid-specific protein 1 Pkinase PF00069.20 OAP64258.1 - 1e-42 146.1 0.0 1.3e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP64258.1 - 6.8e-17 61.3 0.0 1.2e-16 60.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP64258.1 - 7e-06 25.2 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAP64258.1 - 7.5e-05 21.8 0.0 0.0002 20.5 0.0 1.7 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP64258.1 - 9.8e-05 22.1 0.1 0.00036 20.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 OAP64258.1 - 0.0085 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family adh_short PF00106.20 OAP64261.1 - 4.9e-27 94.8 0.1 7.2e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64261.1 - 4.3e-12 46.3 0.0 5.6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64261.1 - 3.8e-09 36.4 0.0 5.6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP64261.1 - 0.001 18.8 0.1 0.12 12.2 0.1 2.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAP64261.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 OAP64262.1 - 2e-09 36.5 2.1 3.5e-09 35.7 1.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 OAP64263.1 - 1.5e-42 145.6 9.2 2.2e-42 145.1 6.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Rhomboid PF01694.17 OAP64263.1 - 2.8 7.9 16.9 0.24 11.3 3.4 2.5 1 1 1 2 2 2 0 Rhomboid family ADH_zinc_N_2 PF13602.1 OAP64264.1 - 2.9e-27 96.0 0.0 7e-27 94.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAP64264.1 - 3e-15 55.8 0.0 5.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP64264.1 - 0.036 13.8 0.2 3.1 7.6 0.0 3.2 2 2 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain DUF925 PF06042.6 OAP64266.1 - 9.7e-48 161.8 0.0 1.1e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF925) Sugar_tr PF00083.19 OAP64267.1 - 1.2e-89 301.0 31.0 1.5e-89 300.7 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64267.1 - 1e-26 93.5 64.1 6.8e-26 90.8 22.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 OAP64267.1 - 1.6e-07 30.3 6.8 8.8e-06 24.6 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF791) TRI12 PF06609.8 OAP64267.1 - 4.4e-05 21.8 0.2 4.4e-05 21.8 0.1 2.2 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 OAP64267.1 - 0.099 12.7 1.5 0.36 10.9 0.2 2.3 2 0 0 2 2 2 0 Phage holin family 2 Cu-oxidase_2 PF07731.9 OAP64268.1 - 3.5e-46 156.1 8.4 9.7e-42 141.7 0.7 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 OAP64268.1 - 1.4e-41 140.9 5.6 1.1e-39 134.7 0.6 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 OAP64268.1 - 5.9e-39 133.5 3.0 5e-32 111.0 0.1 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 OAP64268.1 - 0.051 13.4 0.0 21 5.0 0.0 3.4 3 0 0 3 3 3 0 Cupredoxin-like domain COX2 PF00116.15 OAP64268.1 - 0.06 13.1 2.7 1.9 8.3 0.2 3.7 3 1 1 4 4 4 0 Cytochrome C oxidase subunit II, periplasmic domain FTR1 PF03239.9 OAP64269.1 - 4.9e-88 295.0 8.4 5.8e-88 294.7 5.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4401 PF14351.1 OAP64269.1 - 0.0022 17.0 2.6 0.0022 17.0 1.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4401) DUF3169 PF11368.3 OAP64269.1 - 0.18 10.9 7.3 0.11 11.6 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) 2OG-FeII_Oxy_3 PF13640.1 OAP64270.1 - 0.00031 21.1 0.0 0.00048 20.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 OAP64270.1 - 0.00046 19.6 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe dioxygenase Tet_JBP PF12851.2 OAP64270.1 - 0.023 14.0 0.0 0.048 12.9 0.0 1.5 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily Fungal_trans_2 PF11951.3 OAP64271.1 - 1.8e-09 36.7 0.1 1.3e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain OTT_1508_deam PF14441.1 OAP64272.1 - 9.7e-11 41.6 0.0 2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase MFS_1 PF07690.11 OAP64273.1 - 4.1e-44 150.7 40.4 1.1e-42 146.0 28.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP64273.1 - 7.2e-14 50.9 15.5 9.2e-14 50.5 10.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 OAP64273.1 - 0.31 9.0 10.5 0.14 10.1 0.6 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 OAP64274.1 - 3.1e-06 26.2 0.2 1.3e-05 24.1 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64274.1 - 3.6 7.5 7.4 7.3 6.5 5.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4243 PF14027.1 OAP64275.1 - 4.3e-76 256.4 0.0 5e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Fungal_trans_2 PF11951.3 OAP64276.1 - 0.003 16.2 0.1 0.012 14.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1772 PF08592.6 OAP64277.1 - 2.6e-30 104.9 1.2 3.5e-30 104.5 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) GDH_N PF12466.3 OAP64277.1 - 0.088 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Fungal_trans PF04082.13 OAP64278.1 - 4.8e-32 110.8 0.0 6.7e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64278.1 - 4.2e-08 32.9 5.6 8.5e-08 31.9 3.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 OAP64279.1 - 4.1e-15 56.0 0.0 1.1e-14 54.6 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 OAP64279.1 - 0.00024 20.6 0.0 0.0094 15.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAP64279.1 - 0.051 13.3 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 OAP64280.1 - 1.8e-18 66.3 0.8 3.2e-18 65.5 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Syntaxin-6_N PF09177.6 OAP64280.1 - 0.036 14.4 0.4 0.082 13.3 0.3 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal NAD_binding_10 PF13460.1 OAP64282.1 - 3e-14 53.4 0.0 4.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP64282.1 - 3.5e-06 26.4 0.0 5.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 OAP64282.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 OAP64282.1 - 0.038 13.9 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 OAP64282.1 - 0.05 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP64282.1 - 0.14 11.0 0.0 0.6 8.9 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein MFS_1 PF07690.11 OAP64283.1 - 9.5e-19 67.3 39.5 9.5e-19 67.3 27.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF202 PF02656.10 OAP64283.1 - 0.086 13.0 1.5 0.61 10.3 0.1 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF202) Methyltransf_2 PF00891.13 OAP64284.1 - 5.9e-16 58.4 0.1 1.3e-15 57.2 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 OAP64284.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 OAP64285.1 - 0.0095 15.1 0.0 0.0098 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AA_permease_2 PF13520.1 OAP64286.1 - 5.1e-60 203.1 48.2 6.2e-60 202.9 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP64286.1 - 8.2e-14 50.8 39.5 1.2e-13 50.2 27.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2759 PF10958.3 OAP64286.1 - 8.7 6.0 13.4 1.3 8.6 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2759) Na_Ca_ex PF01699.19 OAP64287.1 - 2.5e-38 130.8 41.0 4.6e-22 78.1 11.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein FAM176 PF14851.1 OAP64287.1 - 9.2 5.9 8.3 36 3.9 3.0 2.8 2 0 0 2 2 2 0 FAM176 family HATPase_c PF02518.21 OAP64288.1 - 8.3e-23 80.2 0.0 2.7e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAP64288.1 - 2e-20 72.8 0.7 4.4e-20 71.7 0.5 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 OAP64288.1 - 1e-13 51.5 0.0 1.8e-11 44.3 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 OAP64288.1 - 1e-12 48.0 0.0 6.7e-08 32.5 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 OAP64288.1 - 2e-12 46.8 0.1 1.2e-11 44.3 0.0 2.5 3 0 0 3 3 3 1 PAS fold HisKA PF00512.20 OAP64288.1 - 1.2e-07 31.6 1.8 3e-07 30.3 0.2 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 OAP64288.1 - 3.8e-06 26.9 0.1 9.3e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 OAP64288.1 - 0.0072 16.1 0.0 0.027 14.3 0.0 2.0 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.1 OAP64288.1 - 0.015 15.7 0.0 1.2 9.6 0.0 2.9 1 1 1 2 2 2 0 GAF domain HATPase_c_5 PF14501.1 OAP64288.1 - 0.13 11.9 0.1 0.83 9.3 0.0 2.4 2 0 0 2 2 2 0 GHKL domain MFS_1 PF07690.11 OAP64289.1 - 1e-21 77.1 42.7 2e-17 62.9 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.23 OAP64290.1 - 4.6e-12 45.7 0.1 8.2e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain PPV_E2_C PF00511.12 OAP64290.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 E2 (early) protein, C terminal PAP2 PF01569.16 OAP64291.1 - 5.7e-19 68.0 4.4 1.3e-18 66.8 3.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily MgtE PF01769.11 OAP64291.1 - 0.34 11.1 2.3 0.34 11.1 0.2 1.8 2 0 0 2 2 2 0 Divalent cation transporter adh_short PF00106.20 OAP64293.1 - 1.6e-21 76.9 0.4 4.6e-21 75.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64293.1 - 2.9e-15 56.6 0.0 5.5e-15 55.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64293.1 - 1e-08 35.0 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP64293.1 - 0.091 12.1 0.1 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SPRY PF00622.23 OAP64294.1 - 2.2e-19 69.7 0.0 3.3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Acetyltransf_1 PF00583.19 OAP64295.1 - 0.0076 16.2 0.0 0.0095 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 OAP64295.1 - 0.089 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PDEase_II PF02112.10 OAP64296.1 - 8.8e-52 176.0 0.0 1.4e-23 83.3 0.0 3.2 3 1 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 OAP64296.1 - 0.0051 16.3 0.0 0.01 15.3 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Cupin_2 PF07883.6 OAP64297.1 - 1.5e-11 43.5 0.5 1.5e-11 43.5 0.4 2.4 2 1 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 OAP64297.1 - 6.3e-07 28.9 0.0 8.8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 OAP64297.1 - 0.0022 17.7 0.1 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain GPI PF06560.6 OAP64297.1 - 0.0064 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) FdtA PF05523.6 OAP64297.1 - 0.03 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 WxcM-like, C-terminal Pirin PF02678.11 OAP64297.1 - 0.031 14.1 0.1 0.031 14.1 0.0 2.0 2 0 0 2 2 2 0 Pirin NHase_beta PF02211.10 OAP64297.1 - 0.066 12.9 1.8 0.088 12.4 1.3 1.1 1 0 0 1 1 1 0 Nitrile hydratase beta subunit JmjC PF02373.17 OAP64297.1 - 0.069 13.4 0.1 0.27 11.4 0.1 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase Zip PF02535.17 OAP64297.1 - 1.4 7.8 4.6 1.6 7.6 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter COesterase PF00135.23 OAP64298.1 - 5.5e-83 279.4 0.0 6.8e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP64298.1 - 0.00012 21.7 0.6 0.00044 19.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold SLAC1 PF03595.12 OAP64299.1 - 2.8e-84 282.5 52.2 3.3e-84 282.3 36.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Phospho_p8 PF10195.4 OAP64299.1 - 0.072 12.9 0.5 0.12 12.2 0.4 1.2 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 Rad1 PF02144.11 OAP64300.1 - 1.3e-81 273.3 0.0 1.6e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 NADH5_C PF06455.6 OAP64301.1 - 0.011 15.1 0.3 0.011 15.1 0.2 1.0 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus Ni_hydr_CYTB PF01292.15 OAP64301.1 - 0.021 14.2 0.3 0.021 14.2 0.2 1.0 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TCR_zetazeta PF11628.3 OAP64301.1 - 0.073 12.5 1.0 0.13 11.7 0.7 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain Cytochrom_B_N PF00033.14 OAP64301.1 - 0.11 11.7 0.9 0.11 11.8 0.6 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF4131 PF13567.1 OAP64301.1 - 0.32 10.3 2.9 0.38 10.1 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Bromodomain PF00439.20 OAP64303.1 - 6.8e-27 93.2 0.5 1.7e-26 91.9 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 OAP64303.1 - 8.9e-10 38.5 0.1 1.7e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP64303.1 - 2.7e-09 36.9 0.0 4.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 OAP64303.1 - 0.055 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RGS PF00615.14 OAP64304.1 - 7.1e-12 45.4 0.0 8.9e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain COX4_pro PF03626.9 OAP64304.1 - 0.025 14.6 0.6 0.025 14.6 0.4 2.1 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV E1-E2_ATPase PF00122.15 OAP64306.1 - 8.3e-56 188.5 0.4 2.6e-55 186.9 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 OAP64306.1 - 2.8e-44 149.0 0.0 1.8e-10 40.8 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 OAP64306.1 - 2.6e-42 145.6 0.3 7.5e-42 144.1 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAP64306.1 - 7.4e-13 49.0 0.0 2e-11 44.4 0.0 3.1 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAP64306.1 - 0.00091 18.8 0.7 0.059 12.9 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.14 OAP64306.1 - 0.0012 18.7 2.4 1.5 8.7 0.0 4.4 3 1 2 5 5 5 1 B12 binding domain WSS_VP PF12175.3 OAP64306.1 - 0.031 13.3 0.1 2.8 6.9 0.0 2.5 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP DUF1884 PF08967.5 OAP64306.1 - 0.039 14.0 1.4 3.7 7.6 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1884) PaaX PF07848.7 OAP64306.1 - 0.046 13.7 1.2 24 5.0 0.0 4.5 5 0 0 5 5 5 0 PaaX-like protein TM_helix PF05552.7 OAP64306.1 - 0.31 10.7 3.0 0.95 9.1 2.1 1.8 1 0 0 1 1 1 0 Conserved TM helix MFS_1 PF07690.11 OAP64307.1 - 2.5e-23 82.3 36.6 2.5e-23 82.3 25.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_N PF00732.14 OAP64308.1 - 4.6e-57 193.4 0.0 6.5e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP64308.1 - 4e-32 111.5 0.1 6.9e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP64308.1 - 0.001 18.0 0.3 0.0061 15.5 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP64308.1 - 0.0032 16.4 0.2 0.0055 15.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP64308.1 - 0.0039 16.0 1.7 0.03 13.1 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP64308.1 - 0.0041 17.1 0.4 0.55 10.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP64308.1 - 0.0084 16.1 2.4 0.0093 15.9 0.5 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Aldo_ket_red PF00248.16 OAP64309.1 - 8.8e-51 172.3 0.0 1.1e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UQ_con PF00179.21 OAP64310.1 - 1.2e-46 157.6 0.0 1.5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAP64310.1 - 0.00021 21.1 0.3 0.00046 20.0 0.2 1.8 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 OAP64310.1 - 0.0049 16.6 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 OAP64310.1 - 0.023 14.4 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.6 OAP64310.1 - 0.055 12.9 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase PF00069.20 OAP64311.1 - 3.8e-55 186.8 0.0 5.4e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP64311.1 - 8.2e-24 84.0 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP64311.1 - 3.6e-08 32.7 0.0 4.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAP64311.1 - 0.0066 15.5 0.0 0.016 14.3 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP64311.1 - 0.033 13.9 0.1 0.17 11.6 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family SCP2 PF02036.12 OAP64312.1 - 2.7e-23 82.2 0.4 3.1e-23 81.9 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 OAP64312.1 - 1.6e-06 28.1 0.1 1.8e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 OAP64312.1 - 0.12 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain DUF2945 PF11160.3 OAP64313.1 - 9.9e-12 44.5 0.6 3.5e-11 42.7 0.4 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Fungal_trans_2 PF11951.3 OAP64314.1 - 1.8e-07 30.0 0.0 2.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 OAP64316.1 - 6e-25 88.5 0.0 1e-24 87.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP64316.1 - 2.5e-17 62.2 1.7 2.1e-16 59.2 0.3 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP64316.1 - 1.9e-11 43.7 0.0 7.7e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP64316.1 - 2.4e-07 29.9 0.3 1.5e-06 27.4 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP64316.1 - 0.00026 20.8 0.7 0.073 12.8 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP64316.1 - 0.00044 20.2 0.0 0.001 18.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP64316.1 - 0.048 14.0 0.0 5.3 7.5 0.0 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP64316.1 - 0.17 10.9 0.0 6.2 5.8 0.0 2.4 3 0 0 3 3 3 0 Thi4 family Ank_2 PF12796.2 OAP64317.1 - 4.3e-20 71.8 0.0 3.3e-19 69.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAP64317.1 - 4.4e-17 60.9 0.5 4.9e-07 29.2 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat NACHT PF05729.7 OAP64317.1 - 6.6e-13 48.6 0.0 1.1e-11 44.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Ank_3 PF13606.1 OAP64317.1 - 2.9e-12 45.5 0.1 7.9e-05 22.5 0.0 5.2 5 0 0 5 5 4 2 Ankyrin repeat Ank_4 PF13637.1 OAP64317.1 - 5.8e-11 42.5 0.1 1.2e-07 32.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAP64317.1 - 1.8e-09 37.5 0.0 8.1e-05 22.7 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 OAP64317.1 - 1.8e-05 24.8 0.1 9e-05 22.5 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAP64317.1 - 0.00054 20.1 0.2 0.0031 17.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 OAP64317.1 - 0.014 15.5 0.0 0.061 13.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 OAP64317.1 - 0.021 13.7 0.1 0.15 11.0 0.1 2.0 1 1 1 2 2 2 0 KAP family P-loop domain AAA_10 PF12846.2 OAP64317.1 - 0.023 14.1 0.1 1 8.7 0.0 2.8 2 1 0 2 2 2 0 AAA-like domain P53_TAD PF08563.6 OAP64317.1 - 0.048 12.7 0.6 0.14 11.2 0.4 1.8 1 0 0 1 1 1 0 P53 transactivation motif SRP19 PF01922.12 OAP64318.1 - 1.3e-19 70.5 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein CDC45 PF02724.9 OAP64319.1 - 0.97 7.3 15.4 1.4 6.8 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BTB PF00651.26 OAP64320.1 - 4.4e-05 23.4 0.0 8.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.13 OAP64322.1 - 3.7e-20 71.8 0.4 7.3e-20 70.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4610 PF15384.1 OAP64322.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) Nol1_Nop2_Fmu PF01189.12 OAP64323.1 - 1.6e-20 73.6 0.0 2.8e-14 53.1 0.0 2.7 2 1 0 2 2 2 2 NOL1/NOP2/sun family NDUF_B4 PF07225.7 OAP64324.1 - 0.021 14.6 0.1 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GST_C PF00043.20 OAP64325.1 - 1.5e-09 37.6 0.0 2.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP64325.1 - 3.3e-09 36.6 0.0 6.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAP64325.1 - 3.7e-09 36.6 0.0 7.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP64325.1 - 4.6e-09 36.3 0.0 9.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP64325.1 - 9.1e-08 31.8 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP64325.1 - 1.8e-06 28.3 0.0 3.4e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BTB_2 PF02214.17 OAP64326.1 - 2.2e-06 27.7 0.0 0.0062 16.7 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DEAD PF00270.24 OAP64327.1 - 3.5e-32 111.2 0.1 1.7e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP64327.1 - 2e-17 62.7 0.0 6.4e-17 61.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP64327.1 - 1.3e-07 31.5 0.3 2e-06 27.7 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 OAP64327.1 - 0.013 13.9 0.0 0.16 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Nop25 PF09805.4 OAP64327.1 - 1.1 9.3 18.4 0.027 14.5 7.3 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Spore_coat_CotO PF14153.1 OAP64327.1 - 6.3 6.1 13.1 3.9 6.8 6.8 2.2 2 0 0 2 2 2 0 Spore coat protein CotO PIGA PF08288.7 OAP64328.1 - 2.2e-45 152.9 2.1 2.2e-45 152.9 1.4 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 OAP64328.1 - 1.5e-29 102.6 0.0 2.2e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAP64328.1 - 1.6e-17 63.8 0.0 2.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAP64328.1 - 1.8e-17 63.6 0.8 3e-17 62.8 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 OAP64328.1 - 1e-13 51.7 0.0 1.9e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 OAP64328.1 - 1.2e-05 25.1 0.3 2.4e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 OAP64328.1 - 0.0051 17.0 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 OAP64328.1 - 0.092 12.2 0.1 0.52 9.7 0.0 2.1 1 1 0 2 2 2 0 Starch synthase catalytic domain ECH PF00378.15 OAP64329.1 - 1.4e-20 73.5 0.0 9.9e-19 67.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Pyr_redox_3 PF13738.1 OAP64330.1 - 0.065 13.2 0.0 0.24 11.4 0.0 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BCL_N PF04714.8 OAP64330.1 - 0.25 10.9 0.8 14 5.3 0.0 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Abhydrolase_6 PF12697.2 OAP64331.1 - 3.2e-08 33.7 1.6 5.2e-08 33.0 1.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP64331.1 - 3.4e-05 23.5 0.0 0.0001 22.0 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 OAP64331.1 - 5.1e-05 22.6 0.0 9.8e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 OAP64331.1 - 8.6e-05 22.3 0.1 0.00018 21.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP64331.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.13 OAP64331.1 - 0.051 12.8 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) LCAT PF02450.10 OAP64331.1 - 0.14 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase V-ATPase_G PF03179.10 OAP64332.1 - 5.2e-33 113.4 18.1 5.9e-33 113.3 12.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 OAP64332.1 - 0.014 15.2 12.8 0.014 15.2 8.8 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Nop25 PF09805.4 OAP64332.1 - 0.047 13.7 16.2 0.056 13.5 11.2 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) OmpH PF03938.9 OAP64332.1 - 0.18 11.7 14.0 0.24 11.3 9.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HypD PF01924.11 OAP64332.1 - 0.18 10.4 1.7 0.22 10.2 1.2 1.0 1 0 0 1 1 1 0 Hydrogenase formation hypA family DUF2215 PF10225.4 OAP64332.1 - 0.33 10.3 1.1 0.38 10.1 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Striatin PF08232.7 OAP64332.1 - 0.38 11.0 9.1 0.5 10.6 6.3 1.2 1 0 0 1 1 1 0 Striatin family CAF-1_p150 PF11600.3 OAP64332.1 - 0.41 9.9 21.4 0.48 9.7 14.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DAG_kinase_N PF14513.1 OAP64332.1 - 0.43 10.7 5.1 0.2 11.8 1.4 1.8 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus vATP-synt_E PF01991.13 OAP64332.1 - 0.61 9.3 20.7 1.1 8.4 10.1 2.1 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Vfa1 PF08432.5 OAP64332.1 - 0.67 9.9 16.2 0.79 9.7 11.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3552 PF12072.3 OAP64332.1 - 0.82 8.8 23.3 1.9 7.6 16.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) SAPS PF04499.10 OAP64332.1 - 1.1 7.8 8.2 1.1 7.7 5.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_13 PF13166.1 OAP64332.1 - 1.1 7.6 11.6 1.2 7.4 8.0 1.0 1 0 0 1 1 1 0 AAA domain RRF PF01765.14 OAP64332.1 - 1.2 8.6 14.9 2 7.8 10.4 1.4 1 0 0 1 1 1 0 Ribosome recycling factor HAUS6_N PF14661.1 OAP64332.1 - 1.4 8.2 8.1 1.6 7.9 5.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FAM91_C PF14648.1 OAP64332.1 - 1.6 7.5 3.8 1.8 7.2 2.7 1.0 1 0 0 1 1 1 0 FAM91 C-terminus DUF2201_N PF13203.1 OAP64332.1 - 1.7 7.7 5.9 1.9 7.5 4.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 OAP64332.1 - 3.2 5.6 8.4 3.4 5.5 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4604 PF15377.1 OAP64332.1 - 3.4 7.8 20.3 4.4 7.4 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) KfrA_N PF11740.3 OAP64332.1 - 3.5 8.1 11.4 0.55 10.6 3.8 2.3 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term DUF2151 PF10221.4 OAP64332.1 - 3.7 5.6 9.4 4.2 5.4 6.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator U79_P34 PF03064.11 OAP64332.1 - 4 6.8 11.4 4.3 6.7 7.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ATP11 PF06644.6 OAP64332.1 - 4.9 6.5 11.6 6 6.2 8.1 1.1 1 0 0 1 1 1 0 ATP11 protein ATP-synt_F6 PF05511.6 OAP64332.1 - 6.9 6.6 11.8 3.4 7.6 4.6 2.2 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DUF3154 PF11351.3 OAP64332.1 - 7.8 6.2 6.0 7.2 6.3 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) TMPIT PF07851.8 OAP64332.1 - 9.2 5.2 7.5 11 5.0 5.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein HrpE PF06188.7 OAP64332.1 - 9.7 5.8 9.6 70 3.0 6.6 2.0 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E HD_4 PF13328.1 OAP64333.1 - 0.049 13.3 0.1 0.057 13.1 0.1 1.2 1 0 0 1 1 1 0 HD domain DUF2570 PF10828.3 OAP64333.1 - 0.12 12.0 0.3 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) GRP PF07172.6 OAP64334.1 - 0.027 14.9 0.2 13 6.3 0.0 2.4 2 0 0 2 2 2 0 Glycine rich protein family DUF1183 PF06682.7 OAP64334.1 - 0.04 13.5 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Pex14_N PF04695.8 OAP64334.1 - 0.12 12.3 1.4 0.19 11.7 0.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sel1 PF08238.7 OAP64335.1 - 6.2e-32 109.3 41.7 5.9e-08 33.0 0.4 11.1 12 0 0 12 12 12 6 Sel1 repeat TPR_7 PF13176.1 OAP64335.1 - 0.024 14.3 3.3 1.8 8.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAP64335.1 - 0.039 14.3 0.2 5.2 7.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1771 PF08590.5 OAP64335.1 - 0.076 13.0 1.1 13 5.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) TPR_2 PF07719.12 OAP64335.1 - 0.11 12.4 13.0 11 6.1 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP64335.1 - 1.7 9.4 12.5 3.7 8.3 0.6 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat FAD_binding_3 PF01494.14 OAP64337.1 - 4.4e-17 62.1 0.0 9e-17 61.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP64337.1 - 4e-07 29.2 0.3 0.0018 17.2 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP64337.1 - 1.3e-05 25.1 0.7 0.00014 21.8 0.5 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP64337.1 - 1.5e-05 24.9 0.1 5.8e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 OAP64337.1 - 0.00015 20.7 0.1 0.023 13.5 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 OAP64337.1 - 0.00037 20.8 0.5 0.0028 18.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 OAP64337.1 - 0.00061 19.3 0.2 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 OAP64337.1 - 0.00076 18.4 0.6 0.0013 17.6 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP64337.1 - 0.0048 16.9 0.1 0.02 14.9 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP64337.1 - 0.014 13.8 0.5 0.066 11.6 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 OAP64337.1 - 0.038 13.0 0.0 0.21 10.6 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 OAP64337.1 - 0.14 10.7 0.1 2.3 6.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Ribosomal_60s PF00428.14 OAP64337.1 - 4.5 7.7 14.7 1 9.7 5.3 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Aldedh PF00171.17 OAP64338.1 - 3.5e-161 536.6 0.1 3.9e-161 536.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fer4_14 PF13394.1 OAP64338.1 - 0.12 12.4 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain ELO PF01151.13 OAP64339.1 - 2.9e-09 36.6 10.9 5.7e-09 35.6 7.6 1.5 1 1 0 1 1 1 1 GNS1/SUR4 family RINT1_TIP1 PF04437.8 OAP64340.1 - 9.4e-130 433.4 0.0 1.5e-129 432.7 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Clusterin PF01093.12 OAP64340.1 - 0.022 13.5 5.6 0.029 13.1 3.0 1.8 2 0 0 2 2 2 0 Clusterin Nup54 PF13874.1 OAP64340.1 - 0.043 13.4 9.5 0.16 11.6 6.6 2.0 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Prominin PF05478.6 OAP64340.1 - 0.29 8.6 9.3 0.43 8.0 6.5 1.1 1 0 0 1 1 1 0 Prominin DNA_ligase_A_M PF01068.16 OAP64341.1 - 1.1e-49 168.5 0.6 5.4e-47 159.7 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAP64341.1 - 7.2e-40 136.6 0.0 1.4e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 OAP64341.1 - 8.3e-20 71.0 0.0 2.2e-18 66.4 0.0 3.1 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Amidase PF01425.16 OAP64342.1 - 1.1e-80 271.6 0.0 1.6e-80 271.1 0.0 1.1 1 0 0 1 1 1 1 Amidase adh_short PF00106.20 OAP64343.1 - 1.4e-16 60.8 0.0 2.6e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP64343.1 - 3.7e-11 43.0 0.1 6.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP64343.1 - 1.3e-05 24.7 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAP64343.1 - 0.00028 20.7 0.0 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 OAP64343.1 - 0.0065 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein HATPase_c PF02518.21 OAP64343.1 - 0.062 13.0 0.1 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3Beta_HSD PF01073.14 OAP64343.1 - 0.1 11.2 0.0 0.3 9.7 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 OAP64344.1 - 1.5e-20 73.4 0.0 2.5e-20 72.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP64344.1 - 6.7e-19 67.9 0.1 2.9e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP64344.1 - 4.9e-05 22.4 0.0 0.00012 21.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAP64344.1 - 0.027 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 OAP64344.1 - 0.046 12.9 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) 7tm_6 PF02949.15 OAP64345.1 - 0.28 9.9 1.4 0.29 9.9 1.0 1.0 1 0 0 1 1 1 0 7tm Odorant receptor HisKA_3 PF07730.8 OAP64346.1 - 0.47 10.8 5.2 3.7 7.9 1.6 2.6 2 0 0 2 2 2 0 Histidine kinase Abhydrolase_6 PF12697.2 OAP64347.1 - 4.6e-11 43.0 1.8 9.7e-11 41.9 1.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP64347.1 - 0.043 13.3 0.0 0.084 12.4 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Prenyltransf PF01255.14 OAP64347.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Sec63 PF02889.11 OAP64348.1 - 8.4e-44 150.0 0.0 8.2e-43 146.8 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 OAP64348.1 - 2.3e-17 62.4 0.4 4.9e-17 61.4 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Bromo_coat PF01318.13 OAP64348.1 - 0.081 12.6 0.3 14 5.3 0.5 2.3 2 0 0 2 2 2 0 Bromovirus coat protein Oxysterol_BP PF01237.13 OAP64349.1 - 5.7e-91 304.6 0.0 9.2e-91 303.9 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein DUF3605 PF12239.3 OAP64349.1 - 7.8e-42 142.8 0.5 1.9e-41 141.5 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.15 OAP64350.1 - 3.8e-21 75.7 0.0 6.4e-21 75.0 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family TFIIA PF03153.8 OAP64351.1 - 8.1e-59 200.3 5.3 1.1e-58 200.0 3.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 OAP64351.1 - 1.1 7.3 16.9 1.5 6.9 11.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bap31 PF05529.7 OAP64352.1 - 3.1e-64 215.9 4.4 3.5e-64 215.8 3.1 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Mod_r PF07200.8 OAP64352.1 - 0.00064 19.6 3.0 0.0011 18.9 2.1 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF4047 PF13256.1 OAP64352.1 - 0.0037 17.2 2.0 0.0059 16.5 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4047) Cep57_MT_bd PF06657.8 OAP64352.1 - 0.022 14.7 2.0 0.27 11.1 1.2 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 THOC7 PF05615.8 OAP64352.1 - 0.035 14.3 1.4 0.055 13.7 1.0 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Lge1 PF11488.3 OAP64352.1 - 0.063 13.4 0.8 0.12 12.6 0.5 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DivIC PF04977.10 OAP64352.1 - 0.064 12.7 6.0 0.95 8.9 2.8 2.6 2 0 0 2 2 2 0 Septum formation initiator Macoilin PF09726.4 OAP64352.1 - 0.077 11.2 2.1 0.092 11.0 1.4 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF948 PF06103.6 OAP64352.1 - 0.11 12.3 0.7 0.46 10.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 OAP64352.1 - 0.15 11.8 7.9 0.3 10.9 5.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_Maf PF03131.12 OAP64352.1 - 0.16 12.2 2.9 0.27 11.5 2.0 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 OAP64352.1 - 5.6 6.5 10.6 0.064 12.8 2.1 1.7 2 0 0 2 2 2 0 IncA protein TPX2 PF06886.6 OAP64352.1 - 6.7 6.8 7.3 7.3 6.7 1.5 2.6 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) COesterase PF00135.23 OAP64353.1 - 2.1e-89 300.6 0.2 3e-89 300.1 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP64353.1 - 0.0011 18.5 1.1 0.0089 15.6 0.4 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold PhoD PF09423.5 OAP64354.1 - 3.1e-158 527.0 4.8 3.6e-158 526.8 3.4 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase NUDIX PF00293.23 OAP64355.1 - 2.2e-16 59.6 0.5 4.8e-16 58.6 0.3 1.6 1 1 0 1 1 1 1 NUDIX domain FYVE PF01363.16 OAP64356.1 - 4.7e-16 58.4 7.1 6.8e-16 57.9 4.9 1.2 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 OAP64356.1 - 0.17 11.7 13.2 0.15 11.9 7.1 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger IBR PF01485.16 OAP64356.1 - 0.27 11.1 6.8 0.085 12.7 2.2 1.9 2 0 0 2 2 2 0 IBR domain zf-RING_5 PF14634.1 OAP64356.1 - 6.6 6.5 12.4 34 4.2 5.6 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Prp18 PF02840.10 OAP64357.1 - 7.6e-50 168.5 0.0 7.6e-50 168.5 0.0 1.7 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 OAP64357.1 - 1e-07 31.0 0.7 1e-07 31.0 0.5 3.7 4 1 1 5 5 5 1 pre-mRNA processing factor 4 (PRP4) like CAF-1_p150 PF11600.3 OAP64357.1 - 0.0031 16.9 23.3 0.0058 16.0 16.2 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal GalP_UDP_tr_C PF02744.12 OAP64357.1 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain CDC27 PF09507.5 OAP64357.1 - 4 6.5 15.3 6 5.9 10.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 U79_P34 PF03064.11 OAP64357.1 - 4.6 6.6 12.3 10 5.5 8.5 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 cNMP_binding PF00027.24 OAP64358.1 - 1.1e-37 127.6 0.0 2.3e-20 72.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 OAP64358.1 - 1e-10 40.5 10.8 0.017 15.1 0.1 8.8 10 0 0 10 10 10 1 Leucine Rich repeat LRR_8 PF13855.1 OAP64358.1 - 3.1e-06 26.8 0.9 0.01 15.5 0.1 5.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.2 OAP64358.1 - 0.00012 21.5 0.3 0.83 9.3 0.0 5.8 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 OAP64358.1 - 0.00029 20.4 0.8 0.00069 19.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAP64358.1 - 0.038 13.6 0.0 0.038 13.6 0.0 3.5 4 0 0 4 4 4 0 F-box domain LRR_1 PF00560.28 OAP64358.1 - 0.063 13.3 17.5 54 4.4 0.2 8.7 10 1 0 10 10 10 0 Leucine Rich Repeat DUF3017 PF11222.3 OAP64359.1 - 0.012 15.3 0.5 0.023 14.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) RasGAP PF00616.14 OAP64361.1 - 0.0067 16.1 1.5 0.0074 15.9 0.1 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase NdhN PF11909.3 OAP64361.1 - 0.058 12.7 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Fungal_trans_2 PF11951.3 OAP64362.1 - 3.7e-05 22.5 0.0 0.00022 19.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain GST_N_2 PF13409.1 OAP64363.1 - 1.5e-07 31.3 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAP64363.1 - 2.2e-06 27.7 0.0 4.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP64363.1 - 6e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAP64363.1 - 0.00037 20.5 0.0 0.00095 19.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP64363.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP64363.1 - 0.035 14.5 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain A_deaminase PF00962.17 OAP64364.1 - 1.3e-60 205.0 0.0 2.5e-43 148.2 0.0 2.0 1 1 1 2 2 2 2 Adenosine/AMP deaminase Abhydrolase_6 PF12697.2 OAP64365.1 - 4.9e-06 26.5 0.0 1.8e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP64365.1 - 0.00026 20.6 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 OAP64365.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 OAP64365.1 - 0.041 13.1 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pkinase PF00069.20 OAP64367.1 - 3.1e-55 187.1 0.0 5.3e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP64367.1 - 1.4e-18 66.9 0.0 5.1e-18 65.0 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase TAF4 PF05236.9 OAP64368.1 - 8.9e-19 67.7 0.1 3.4e-16 59.3 0.0 3.2 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family PP2C PF00481.16 OAP64368.1 - 0.16 11.3 1.7 9.8 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C SRP-alpha_N PF04086.8 OAP64368.1 - 0.35 10.2 10.1 0.67 9.2 7.0 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Rtf2 PF04641.7 OAP64368.1 - 0.87 8.7 5.9 1.6 7.9 4.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger CPSF73-100_C PF11718.3 OAP64369.1 - 6.6e-68 228.2 0.0 1.1e-66 224.3 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 OAP64369.1 - 5.9e-32 110.2 0.0 1.3e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 OAP64369.1 - 3.7e-15 56.1 1.2 4.7e-15 55.7 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP64369.1 - 1.1e-09 38.0 1.6 1.3e-09 37.8 0.2 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 OAP64369.1 - 2.8e-07 30.2 0.2 6e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 OAP64369.1 - 5e-06 26.3 0.9 3.3e-05 23.6 0.1 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain adh_short PF00106.20 OAP64370.1 - 3.4e-16 59.6 3.1 2.1e-09 37.5 0.0 2.7 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.5 OAP64370.1 - 0.074 12.7 2.4 0.28 10.8 0.0 2.4 2 1 0 2 2 2 0 KR domain HEAT PF02985.17 OAP64371.1 - 1.1e-16 59.3 10.1 0.00046 20.0 0.1 9.3 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 OAP64371.1 - 5e-14 52.3 7.9 0.00024 21.3 0.0 6.8 3 2 5 8 8 8 6 HEAT repeats IBN_N PF03810.14 OAP64371.1 - 5.5e-12 45.4 0.7 1.8e-10 40.5 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 OAP64371.1 - 2.1e-07 31.1 23.3 0.00026 21.3 0.0 9.8 7 2 4 11 11 11 2 HEAT-like repeat RIX1 PF08167.7 OAP64371.1 - 0.00021 21.0 0.5 0.03 14.0 0.3 3.8 2 1 0 3 3 3 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 OAP64371.1 - 0.0023 17.2 0.4 3.5 6.9 0.0 4.5 3 1 1 4 4 4 1 CLASP N terminal Arm PF00514.18 OAP64371.1 - 0.38 10.6 8.5 4.4 7.2 0.0 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Apc4 PF12896.2 OAP64372.1 - 1.7e-49 167.9 0.0 2.6e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 OAP64372.1 - 0.0034 16.8 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 OAP64372.1 - 0.0042 16.9 0.1 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2639 PF11121.3 OAP64372.1 - 0.15 11.6 0.1 0.93 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2639) Tox-WTIP PF15654.1 OAP64373.1 - 0.048 13.2 0.2 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif Peptidase_M14 PF00246.19 OAP64374.1 - 5.3e-64 216.5 0.0 6.8e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase TCTP PF00838.12 OAP64375.1 - 1.3e-49 168.3 1.1 1.5e-49 168.1 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FDX-ACB PF03147.9 OAP64375.1 - 0.12 12.5 0.4 12 6.1 0.0 2.2 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain FA_hydroxylase PF04116.8 OAP64376.1 - 1.6e-17 63.9 12.3 1.6e-17 63.9 8.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Lactamase_B_2 PF12706.2 OAP64378.1 - 2.8e-31 108.5 0.1 5.5e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 OAP64378.1 - 1.5e-22 78.8 0.1 5.8e-21 73.7 0.0 2.5 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 OAP64378.1 - 3.1e-06 26.9 0.0 7.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_1 PF00170.16 OAP64379.1 - 7.2e-10 38.6 16.9 8.1e-10 38.5 9.2 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 OAP64379.1 - 0.00013 21.7 15.1 0.00013 21.7 10.5 2.4 2 1 0 2 2 2 1 Basic region leucine zipper PilO PF04350.8 OAP64379.1 - 0.0023 17.8 2.5 0.0023 17.8 1.7 2.6 3 0 0 3 3 3 1 Pilus assembly protein, PilO Chibby PF14645.1 OAP64379.1 - 0.013 15.3 0.9 0.013 15.3 0.6 2.1 2 0 0 2 2 2 0 Chibby family bZIP_Maf PF03131.12 OAP64379.1 - 0.018 15.3 9.5 0.018 15.3 6.6 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF2381 PF09544.5 OAP64379.1 - 0.94 8.5 8.1 0.083 11.9 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2381) DUF972 PF06156.8 OAP64379.1 - 4.4 7.6 7.3 0.46 10.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 OAP64379.1 - 5.6 6.5 12.9 0.24 10.8 2.2 2.5 2 0 0 2 2 2 0 Septum formation initiator MoaC PF01967.16 OAP64380.1 - 1.6e-38 131.4 0.0 4.1e-38 130.1 0.0 1.7 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 OAP64380.1 - 1.8e-35 121.4 1.4 4.4e-35 120.1 0.0 2.4 2 1 1 3 3 3 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 OAP64380.1 - 3.5e-22 79.3 0.1 6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 OAP64380.1 - 1.2e-06 28.6 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 OAP64380.1 - 3.4e-05 23.8 0.0 9.1e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Terminase_2 PF03592.11 OAP64380.1 - 0.029 14.6 1.9 0.038 14.2 0.1 2.0 2 0 0 2 2 2 0 Terminase small subunit F-box-like PF12937.2 OAP64381.1 - 3.1e-08 33.2 0.0 6.6e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP64381.1 - 0.02 14.5 0.2 0.055 13.1 0.1 1.7 1 0 0 1 1 1 0 F-box domain Gtr1_RagA PF04670.7 OAP64382.1 - 2.9e-70 236.0 1.5 3e-70 235.9 0.3 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 OAP64382.1 - 2.8e-05 23.4 0.0 5.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 OAP64382.1 - 0.00011 22.6 0.0 0.00022 21.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 OAP64382.1 - 0.0013 17.4 1.3 0.0024 16.6 0.9 1.4 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 OAP64382.1 - 0.0017 18.3 0.0 0.03 14.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAP64382.1 - 0.013 14.7 0.0 0.036 13.2 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.17 OAP64382.1 - 0.075 12.4 0.1 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 Ras family Hexapep PF00132.19 OAP64383.1 - 1.1e-07 31.0 13.2 0.0024 17.2 2.7 4.3 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 OAP64383.1 - 0.00069 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 OAP64383.1 - 0.0018 16.9 0.4 0.0027 16.3 0.3 1.2 1 0 0 1 1 1 1 L-fucokinase Eno-Rase_NADH_b PF12242.3 OAP64383.1 - 4.5 7.1 5.8 0.29 10.9 0.3 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hexapep_2 PF14602.1 OAP64383.1 - 7.1 6.2 10.6 2 8.0 0.5 3.4 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase SET PF00856.23 OAP64384.1 - 3.3e-18 66.5 0.8 2.1e-17 63.8 0.2 2.4 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 OAP64384.1 - 5.4e-16 58.7 6.5 5.4e-16 58.7 4.5 2.3 2 0 0 2 2 2 1 Pre-SET motif Glutaredoxin2_C PF04399.8 OAP64385.1 - 0.057 13.0 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF2638 PF10937.3 OAP64386.1 - 9.2 7.3 8.8 6.7 7.7 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) Ion_trans PF00520.26 OAP64387.1 - 8e-101 335.3 77.9 3.8e-33 114.4 1.2 4.8 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 OAP64387.1 - 0.00033 19.7 0.0 0.00093 18.3 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 OAP64387.1 - 0.0052 16.5 0.0 0.025 14.4 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 OAP64387.1 - 0.085 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair PAF-AH_p_II PF03403.8 OAP64389.1 - 1.7e-41 141.8 0.0 1.2e-36 125.7 0.0 2.4 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 OAP64389.1 - 4.3e-08 33.0 0.0 8.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP64389.1 - 0.00027 20.8 0.0 0.001 19.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAP64389.1 - 0.0069 15.3 0.0 0.011 14.6 0.0 1.3 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 OAP64389.1 - 0.014 14.2 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.3 OAP64389.1 - 0.029 14.2 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Ras PF00071.17 OAP64390.1 - 7.6e-49 165.1 0.0 9.3e-49 164.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP64390.1 - 1.2e-14 54.7 0.0 2.7e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP64390.1 - 6.7e-10 38.4 0.0 9.1e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 OAP64390.1 - 0.0005 20.2 0.1 0.0029 17.7 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 OAP64390.1 - 0.0042 16.2 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 OAP64390.1 - 0.029 13.6 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 OAP64390.1 - 0.055 12.1 1.7 0.89 8.1 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 OAP64390.1 - 0.066 13.3 0.2 0.22 11.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 OAP64390.1 - 0.076 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain GRASP55_65 PF04495.9 OAP64391.1 - 3.7e-05 23.7 0.0 7.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 OAP64391.1 - 4e-05 23.4 0.0 8.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 OAP64391.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) RhoGEF PF00621.15 OAP64392.1 - 8.4e-28 97.4 0.0 1.4e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain FAD_binding_8 PF08022.7 OAP64395.1 - 8.2e-23 80.2 0.0 1.8e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAP64395.1 - 9.9e-22 77.5 0.0 1.7e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAP64395.1 - 2.9e-18 66.1 8.4 7.9e-18 64.7 5.8 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAP64395.1 - 7.8e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAP64395.1 - 0.12 12.9 0.0 2.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SBDS PF01172.13 OAP64396.1 - 1.5e-25 88.8 0.2 1.7e-25 88.6 0.1 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 OAP64396.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Phage XkdN-like protein Mannosyl_trans3 PF11051.3 OAP64397.1 - 2e-38 132.3 0.0 2.7e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 OAP64397.1 - 0.017 14.4 0.0 0.092 12.0 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 8 p450 PF00067.17 OAP64398.1 - 9e-81 271.7 0.0 1e-80 271.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NIF PF03031.13 OAP64399.1 - 1e-50 171.5 0.2 1.7e-50 170.8 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydrolase_6 PF12697.2 OAP64400.1 - 1.1e-31 110.5 0.0 1.3e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP64400.1 - 1e-22 80.8 0.0 1.4e-16 60.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP64400.1 - 2.3e-19 69.5 0.0 9.9e-19 67.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP64400.1 - 1.4e-08 34.4 0.0 0.017 14.5 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 OAP64400.1 - 7.1e-05 22.1 0.0 0.0064 15.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 OAP64400.1 - 0.00015 21.5 0.0 0.00039 20.2 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.9 OAP64400.1 - 0.00038 19.0 0.0 0.0012 17.4 0.0 1.7 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 OAP64400.1 - 0.00046 19.9 0.0 0.00084 19.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 OAP64400.1 - 0.0014 17.9 0.0 0.97 8.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF1749 PF08538.5 OAP64400.1 - 0.0075 15.1 0.0 0.52 9.1 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1749) Esterase PF00756.15 OAP64400.1 - 0.037 13.4 0.3 0.062 12.7 0.1 1.5 2 0 0 2 2 2 0 Putative esterase DUF915 PF06028.6 OAP64400.1 - 0.099 11.7 0.1 0.96 8.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) EMP70 PF02990.11 OAP64401.1 - 1.2e-145 485.9 0.0 3.4e-145 484.4 0.0 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3169 PF11368.3 OAP64401.1 - 2.8 7.0 14.4 0.15 11.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Bul1_N PF04425.7 OAP64402.1 - 4.3e-07 28.8 0.7 1.7e-06 26.8 0.1 2.2 2 1 0 2 2 2 1 Bul1 N terminus Arrestin_N PF00339.24 OAP64402.1 - 2.6e-06 27.3 0.0 5.7e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 OAP64402.1 - 0.00037 19.7 0.1 0.00063 19.0 0.1 1.3 1 0 0 1 1 1 1 Bul1 C terminus SCIMP PF15050.1 OAP64404.1 - 0.0064 16.3 0.1 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 SCIMP protein Fungal_trans_2 PF11951.3 OAP64405.1 - 3.9e-06 25.7 0.5 8.2e-06 24.6 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain IU_nuc_hydro PF01156.14 OAP64405.1 - 0.00077 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF4191 PF13829.1 OAP64406.1 - 0.0027 16.8 0.7 0.0027 16.8 0.5 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4191) DuoxA PF10204.4 OAP64406.1 - 0.32 9.9 9.1 2.6 7.0 0.3 2.3 2 0 0 2 2 2 0 Dual oxidase maturation factor EBP PF05241.7 OAP64407.1 - 1.6e-60 203.4 10.8 2.5e-60 202.8 7.5 1.2 1 0 0 1 1 1 1 Emopamil binding protein Collagen PF01391.13 OAP64408.1 - 0.00025 20.5 3.6 0.00025 20.5 2.5 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Sulfotransfer_3 PF13469.1 OAP64408.1 - 0.065 14.1 0.0 0.53 11.2 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase family AAA_2 PF07724.9 OAP64409.1 - 4e-47 160.3 0.0 1e-45 155.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 OAP64409.1 - 9.1e-27 93.8 0.0 1.3e-14 54.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 OAP64409.1 - 2.9e-24 84.7 0.8 1.2e-23 82.7 0.5 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 OAP64409.1 - 4.1e-16 59.5 16.3 7e-06 26.1 0.0 6.9 4 2 3 7 7 7 2 AAA ATPase domain AAA_5 PF07728.9 OAP64409.1 - 2.1e-15 56.6 1.4 1.2e-09 38.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAP64409.1 - 1.7e-14 54.0 0.2 2.3e-05 24.5 0.0 4.1 2 2 1 3 3 3 2 AAA domain Clp_N PF02861.15 OAP64409.1 - 2.6e-09 36.8 5.8 1.5e-05 24.8 0.3 4.1 3 0 0 3 3 3 2 Clp amino terminal domain Sigma54_activat PF00158.21 OAP64409.1 - 7.8e-09 35.2 0.0 2.2e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 OAP64409.1 - 1.9e-07 30.7 0.0 0.033 13.9 0.1 3.7 3 1 0 3 3 3 2 Part of AAA domain AAA_17 PF13207.1 OAP64409.1 - 3.7e-07 30.9 9.8 0.0081 16.9 0.0 4.3 3 2 1 4 4 3 2 AAA domain IstB_IS21 PF01695.12 OAP64409.1 - 3.8e-07 29.6 0.0 0.027 13.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 OAP64409.1 - 6.6e-06 26.4 6.1 0.015 15.6 0.0 4.0 4 1 1 5 5 3 2 AAA domain Mg_chelatase PF01078.16 OAP64409.1 - 1.3e-05 24.4 0.2 0.14 11.3 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAP64409.1 - 1.6e-05 24.9 1.1 0.23 11.3 0.0 3.8 3 1 1 4 4 3 2 AAA domain AAA_33 PF13671.1 OAP64409.1 - 4.3e-05 23.4 1.1 0.2 11.5 0.0 3.5 3 1 1 4 4 2 2 AAA domain T2SE PF00437.15 OAP64409.1 - 4.5e-05 22.4 0.1 0.0045 15.9 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 OAP64409.1 - 7.9e-05 22.7 0.0 0.46 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_3 PF07726.6 OAP64409.1 - 0.00011 21.8 0.0 0.64 9.6 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 OAP64409.1 - 0.00012 21.8 0.0 0.73 9.5 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 OAP64409.1 - 0.00023 20.2 0.2 0.084 11.9 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin Arch_ATPase PF01637.13 OAP64409.1 - 0.00027 20.7 15.7 0.004 16.8 0.2 5.5 3 2 0 4 4 4 1 Archaeal ATPase AAA_29 PF13555.1 OAP64409.1 - 0.00057 19.3 0.0 0.44 10.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAP64409.1 - 0.00086 18.5 0.0 0.35 10.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Torsin PF06309.6 OAP64409.1 - 0.00086 19.1 0.0 0.0053 16.6 0.0 2.2 2 0 0 2 2 2 1 Torsin AAA_25 PF13481.1 OAP64409.1 - 0.0013 18.1 2.8 2.2 7.6 0.0 4.1 4 1 1 5 5 4 2 AAA domain ABC_tran PF00005.22 OAP64409.1 - 0.0013 19.0 4.5 0.84 9.9 0.0 3.8 4 0 0 4 4 3 1 ABC transporter AAA_24 PF13479.1 OAP64409.1 - 0.0015 18.1 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 OAP64409.1 - 0.0049 16.8 0.1 2.3 8.1 0.0 3.3 4 0 0 4 4 3 1 AAA domain NACHT PF05729.7 OAP64409.1 - 0.0056 16.3 0.0 0.76 9.4 0.0 3.0 3 0 0 3 3 2 1 NACHT domain ResIII PF04851.10 OAP64409.1 - 0.0062 16.3 6.6 0.38 10.5 0.0 4.6 4 2 2 6 6 4 1 Type III restriction enzyme, res subunit SRP54 PF00448.17 OAP64409.1 - 0.0071 15.8 0.0 1.5 8.2 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 OAP64409.1 - 0.0086 15.7 0.0 0.4 10.3 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_10 PF12846.2 OAP64409.1 - 0.014 14.8 9.2 0.32 10.3 0.1 5.1 5 1 0 5 5 5 0 AAA-like domain MMR_HSR1 PF01926.18 OAP64409.1 - 0.023 14.6 0.0 0.43 10.5 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 OAP64409.1 - 0.063 12.7 0.0 7.1 6.1 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 OAP64409.1 - 0.069 12.7 0.0 19 4.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 OAP64409.1 - 0.074 11.8 0.0 1.8 7.3 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain Snapin_Pallidin PF14712.1 OAP64409.1 - 0.085 13.1 16.1 0.39 11.0 0.3 3.6 3 1 0 3 3 2 0 Snapin/Pallidin V_ATPase_I PF01496.14 OAP64409.1 - 2.8 5.7 13.6 0.1 10.4 4.7 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 OAP64409.1 - 4.3 6.2 18.7 0.68 8.9 7.1 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 CENP-X PF09415.5 OAP64410.1 - 4.8e-17 61.5 0.0 1.3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Nop14 PF04147.7 OAP64410.1 - 0.00012 20.2 13.0 0.00014 19.9 9.0 1.2 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 OAP64410.1 - 0.00069 18.2 14.1 0.00083 17.9 9.8 1.1 1 0 0 1 1 1 1 Daxx Family CBFD_NFYB_HMF PF00808.18 OAP64410.1 - 0.004 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CDC45 PF02724.9 OAP64410.1 - 0.013 13.5 8.7 0.014 13.4 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 OAP64410.1 - 0.025 13.8 17.8 0.036 13.3 12.4 1.3 1 0 0 1 1 1 0 SDA1 Herpes_UL32 PF06070.6 OAP64410.1 - 0.12 10.8 7.9 0.14 10.5 5.5 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 SAPS PF04499.10 OAP64410.1 - 0.19 10.3 2.7 0.21 10.1 1.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.6 OAP64410.1 - 1.9 7.9 17.9 2.6 7.4 12.4 1.3 1 0 0 1 1 1 0 PPP4R2 Mpp10 PF04006.7 OAP64410.1 - 4.2 5.6 21.5 1.7 6.8 13.4 1.4 2 0 0 2 2 2 0 Mpp10 protein COPI_C PF06957.6 OAP64410.1 - 4.4 5.7 13.4 6.3 5.2 9.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CobT PF06213.7 OAP64410.1 - 4.5 6.3 29.4 7.3 5.6 20.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MGC-24 PF05283.6 OAP64412.1 - 8.1 6.1 11.7 58 3.4 8.1 2.2 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Zn_ribbon_recom PF13408.1 OAP64413.1 - 0.0051 17.0 0.1 0.15 12.3 0.2 2.2 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain zf-BED PF02892.10 OAP64413.1 - 0.012 15.3 0.2 0.023 14.4 0.2 1.4 1 0 0 1 1 1 0 BED zinc finger RecX PF02631.11 OAP64413.1 - 0.078 13.1 0.2 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 RecX family PyrI_C PF02748.10 OAP64413.1 - 0.13 11.7 0.1 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain AT_hook PF02178.14 OAP64413.1 - 1.8 8.4 10.5 5 7.1 7.3 1.8 1 0 0 1 1 1 0 AT hook motif Mis12 PF05859.7 OAP64414.1 - 3.9e-42 143.4 0.6 8.6e-42 142.3 0.0 1.8 2 0 0 2 2 2 1 Mis12 protein DUF770 PF05591.7 OAP64414.1 - 0.19 11.3 1.8 3 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF770) DUF904 PF06005.7 OAP64414.1 - 0.85 9.9 5.3 6.4 7.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) MFS_2 PF13347.1 OAP64415.1 - 0.0044 15.4 0.9 0.0047 15.3 0.6 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein DUF202 PF02656.10 OAP64415.1 - 0.014 15.5 3.0 0.073 13.2 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Glyco_hydro_43 PF04616.9 OAP64416.1 - 5.4e-18 65.0 0.0 7.1e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cu-oxidase_3 PF07732.10 OAP64417.1 - 2.9e-35 120.5 2.3 2.2e-34 117.7 0.3 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP64417.1 - 8.7e-24 83.5 4.3 1.1e-18 67.0 0.1 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 OAP64417.1 - 1.3e-13 51.1 0.4 5.6e-11 42.5 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase Aldedh PF00171.17 OAP64419.1 - 9.5e-144 479.1 0.0 1.1e-143 478.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UDG PF03167.14 OAP64420.1 - 1.3e-19 70.1 0.1 3.6e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Het-C PF07217.6 OAP64421.1 - 2e-265 881.7 0.0 2e-265 881.7 0.0 1.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C Ank_2 PF12796.2 OAP64422.1 - 1.3e-30 105.5 13.9 1e-06 28.9 0.0 10.6 7 4 2 9 9 9 6 Ankyrin repeats (3 copies) Ank PF00023.25 OAP64422.1 - 6.8e-18 63.4 20.6 0.14 11.9 0.0 12.8 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.1 OAP64422.1 - 1.7e-10 41.1 7.4 0.013 15.9 0.0 8.0 9 0 0 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP64422.1 - 9.2e-08 31.6 14.0 2.4 8.6 0.0 11.4 13 0 0 13 13 13 1 Ankyrin repeat IBR PF01485.16 OAP64422.1 - 1.6e-07 31.0 21.1 0.00034 20.4 2.1 3.9 3 1 0 3 3 3 2 IBR domain Ank_5 PF13857.1 OAP64422.1 - 3.9e-05 23.7 17.1 0.015 15.4 0.0 7.9 9 2 2 11 11 11 2 Ankyrin repeats (many copies) SpoIIP PF07454.6 OAP64422.1 - 1 8.4 0.0 1.7 7.7 0.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Cupin_2 PF07883.6 OAP64423.1 - 0.0001 21.6 0.6 0.00023 20.6 0.4 1.6 1 0 0 1 1 1 1 Cupin domain YrvL PF14184.1 OAP64424.1 - 0.84 9.4 12.1 0.022 14.5 4.1 1.5 2 0 0 2 2 2 0 Regulatory protein YrvL FA_desaturase PF00487.19 OAP64424.1 - 1.8 7.9 4.8 2.6 7.4 3.4 1.2 1 0 0 1 1 1 0 Fatty acid desaturase 4HBT_3 PF13622.1 OAP64425.1 - 4.5e-49 167.5 0.3 5.8e-49 167.1 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAP64425.1 - 6.2e-24 84.1 0.0 4.4e-11 42.5 0.0 4.3 3 1 0 3 3 3 3 Acyl-CoA thioesterase Prefoldin_2 PF01920.15 OAP64426.1 - 2.4e-17 62.6 0.4 2.8e-17 62.3 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit End3 PF12761.2 OAP64426.1 - 0.011 15.4 2.0 0.099 12.2 1.4 2.0 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Prefoldin PF02996.12 OAP64426.1 - 0.021 14.4 3.1 0.027 14.1 0.3 1.9 1 1 1 2 2 2 0 Prefoldin subunit Lzipper-MIP1 PF14389.1 OAP64426.1 - 0.038 14.0 2.9 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MerR-DNA-bind PF09278.6 OAP64426.1 - 0.075 13.4 3.7 1.7 9.0 0.5 3.0 3 0 0 3 3 3 0 MerR, DNA binding Nnf1 PF03980.9 OAP64426.1 - 0.079 12.9 1.2 0.11 12.5 0.9 1.3 1 0 0 1 1 1 0 Nnf1 FlaC_arch PF05377.6 OAP64426.1 - 0.1 12.4 1.1 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin PF00804.20 OAP64426.1 - 0.24 11.5 2.7 8.4 6.6 0.3 2.2 2 0 0 2 2 2 0 Syntaxin Bap31 PF05529.7 OAP64426.1 - 0.89 8.9 4.0 9.3 5.6 2.8 2.0 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Isochorismatase PF00857.15 OAP64427.1 - 6.7e-19 68.4 0.0 9.7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family ATG27 PF09451.5 OAP64428.1 - 2.3e-73 246.7 0.0 3.6e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 OAP64428.1 - 0.00014 21.6 0.1 0.02 14.6 0.0 2.5 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat FAM176 PF14851.1 OAP64428.1 - 0.17 11.5 0.9 0.35 10.5 0.6 1.5 1 0 0 1 1 1 0 FAM176 family Peptidase_S49_N PF08496.5 OAP64428.1 - 0.36 10.5 1.6 0.58 9.9 1.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Asp-B-Hydro_N PF05279.6 OAP64428.1 - 0.64 9.8 7.1 0.12 12.1 0.5 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region NAF PF03822.9 OAP64429.1 - 0.053 13.2 0.3 1 9.1 0.0 2.4 2 0 0 2 2 2 0 NAF domain CHAT PF12770.2 OAP64430.1 - 2e-24 86.2 0.3 4.4e-24 85.0 0.2 1.6 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.12 OAP64430.1 - 0.048 12.3 0.0 0.1 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C50 Fib_alpha PF08702.5 OAP64430.1 - 0.074 13.1 1.6 7.9 6.5 0.1 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family TPR_2 PF07719.12 OAP64430.1 - 0.079 12.9 3.5 15 5.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAP64430.1 - 0.11 12.4 0.1 0.11 12.4 0.1 7.1 7 3 3 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP64430.1 - 0.78 10.4 6.6 1.1 9.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Alpha-amylase PF00128.19 OAP64431.1 - 3.3e-52 177.8 0.0 6.3e-50 170.3 0.0 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain SufE PF02657.10 OAP64431.1 - 0.059 12.9 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Fe-S metabolism associated domain Acetyltransf_7 PF13508.1 OAP64432.1 - 9.1e-09 35.3 0.0 8.9e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAP64432.1 - 3.9e-06 26.7 0.0 7.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 OAP64432.1 - 3.6e-05 23.6 0.0 6.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP64432.1 - 0.00052 19.8 0.0 0.00099 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP64432.1 - 0.0039 16.9 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 OAP64432.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rhomboid PF01694.17 OAP64433.1 - 3.3e-09 36.8 10.1 4.2e-09 36.5 7.0 1.1 1 0 0 1 1 1 1 Rhomboid family Fungal_trans_2 PF11951.3 OAP64434.1 - 9.7e-05 21.1 1.0 0.0025 16.5 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Herpes_BLRF2 PF05812.7 OAP64434.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein GMC_oxred_N PF00732.14 OAP64435.1 - 3.3e-55 187.3 0.0 4.4e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP64435.1 - 1.1e-32 113.2 0.1 1.7e-32 112.7 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP64435.1 - 5.3e-05 22.2 0.0 0.0037 16.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP64435.1 - 6e-05 23.0 0.1 0.00022 21.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP64435.1 - 0.00021 20.3 0.0 0.00039 19.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP64435.1 - 0.017 13.9 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.11 OAP64436.1 - 4.4e-26 91.4 26.6 6.4e-26 90.9 18.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2680 PF10925.3 OAP64436.1 - 0.035 13.9 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Thaumatin PF00314.12 OAP64438.1 - 7.4e-70 234.7 4.4 9.2e-70 234.4 3.0 1.1 1 0 0 1 1 1 1 Thaumatin family DUF3455 PF11937.3 OAP64440.1 - 3.7e-40 137.7 0.1 4.9e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 OAP64440.1 - 4.8e-05 23.1 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) CASP_C PF08172.7 OAP64441.1 - 2.2e-84 282.3 0.5 2.2e-84 282.3 0.3 3.7 4 1 0 4 4 4 2 CASP C terminal NAD_binding_1 PF00175.16 OAP64441.1 - 0.35 11.4 1.4 7.1 7.2 0.0 2.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Vps39_2 PF10367.4 OAP64442.1 - 6.2e-07 29.5 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 OAP64442.1 - 0.12 12.4 0.2 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Ras PF00071.17 OAP64443.1 - 8.5e-43 145.5 0.0 1.6e-37 128.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 OAP64443.1 - 3.7e-15 56.4 0.0 6.8e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAP64443.1 - 3e-11 42.8 0.0 5.8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAP64443.1 - 1.9e-05 24.1 0.0 6.3e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAP64443.1 - 0.00026 20.2 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAP64443.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 OAP64443.1 - 0.0015 18.3 0.0 0.0032 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAP64443.1 - 0.003 17.6 0.0 0.0075 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 OAP64443.1 - 0.0066 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 OAP64443.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 OAP64443.1 - 0.02 14.3 0.0 0.31 10.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 OAP64443.1 - 0.029 13.5 0.0 0.044 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAP64443.1 - 0.039 13.9 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 OAP64443.1 - 0.039 14.2 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 OAP64443.1 - 0.061 12.9 0.1 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 OAP64443.1 - 0.08 13.1 0.0 0.26 11.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 OAP64443.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase MFS_1 PF07690.11 OAP64445.1 - 1.4e-36 125.9 31.7 1.4e-36 125.9 22.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 OAP64445.1 - 0.0025 16.5 0.6 0.051 12.2 0.8 2.1 1 1 1 2 2 2 1 BT1 family OATP PF03137.15 OAP64445.1 - 0.0039 15.3 1.8 0.24 9.4 0.2 2.8 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF4044 PF13253.1 OAP64445.1 - 0.019 14.0 1.4 0.1 11.7 1.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Fungal_trans PF04082.13 OAP64447.1 - 8.4e-14 51.0 2.7 2.6e-13 49.4 1.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2278 PF10042.4 OAP64450.1 - 1.4e-64 217.5 0.0 1.6e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) Lipoxygenase PF00305.14 OAP64451.1 - 4.8e-53 180.1 7.2 4.4e-52 176.9 4.9 1.9 1 1 0 1 1 1 1 Lipoxygenase adh_short PF00106.20 OAP64452.1 - 1.9e-31 109.2 0.6 2.9e-31 108.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64452.1 - 2.6e-23 83.0 0.0 3.6e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64452.1 - 1e-12 48.0 0.5 1.9e-12 47.2 0.3 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP64452.1 - 2.2e-05 24.1 0.3 3.6e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Oxidored_nitro PF00148.14 OAP64452.1 - 0.00035 19.3 0.0 0.00061 18.5 0.0 1.4 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Epimerase PF01370.16 OAP64452.1 - 0.0005 19.5 0.1 0.00067 19.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 OAP64452.1 - 0.0013 18.0 0.5 0.0025 17.1 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family Glyco_transf_5 PF08323.6 OAP64452.1 - 0.0015 18.0 0.0 0.014 14.8 0.0 2.2 2 1 1 3 3 3 1 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.14 OAP64452.1 - 0.0017 17.4 0.2 0.0032 16.5 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 OAP64452.1 - 0.023 14.6 0.9 0.086 12.8 0.3 2.1 2 1 0 2 2 2 0 NADH(P)-binding ACT_7 PF13840.1 OAP64452.1 - 0.029 13.8 0.2 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 ACT domain CW_binding_2 PF04122.7 OAP64452.1 - 0.037 14.2 0.3 0.097 12.8 0.2 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 ApbA PF02558.11 OAP64452.1 - 0.07 12.5 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ferric_reduct PF01794.14 OAP64453.1 - 2.8e-15 56.4 10.4 2.8e-15 56.4 7.2 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAP64453.1 - 3.5e-15 56.2 0.1 5e-13 49.2 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAP64453.1 - 6.9e-12 45.1 0.0 4.3e-07 29.7 0.0 2.7 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_1 PF00175.16 OAP64453.1 - 0.032 14.8 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain GAT PF03127.9 OAP64454.1 - 4.3e-13 49.0 0.1 8.4e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 GAT domain Imm15 PF15590.1 OAP64454.1 - 0.094 11.8 0.2 0.21 10.7 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 15 VHS PF00790.14 OAP64454.1 - 0.17 11.4 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 VHS domain His_Phos_2 PF00328.17 OAP64455.1 - 7.5e-23 81.4 0.0 2.7e-21 76.2 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NmrA PF05368.8 OAP64457.1 - 2e-26 92.6 0.0 3.1e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP64457.1 - 0.00041 20.4 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 OAP64457.1 - 0.0038 17.6 0.4 0.45 10.9 0.0 2.8 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 OAP64457.1 - 0.036 14.3 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UBA_4 PF14555.1 OAP64458.1 - 1.5e-07 30.8 3.6 0.00012 21.5 0.0 2.6 2 0 0 2 2 2 2 UBA-like domain UBA_4 PF14555.1 OAP64459.1 - 7.6e-08 31.7 7.4 0.036 13.5 0.3 3.9 3 1 0 3 3 3 3 UBA-like domain Myb_DNA-binding PF00249.26 OAP64459.1 - 0.13 12.3 1.4 7.9 6.6 0.1 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Dus PF01207.12 OAP64460.1 - 1e-58 198.6 0.0 1.4e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Imm20 PF15568.1 OAP64460.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 20 DUF504 PF04457.7 OAP64461.1 - 2.9e-07 30.5 0.9 7.6e-07 29.1 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF504) MAP7 PF05672.6 OAP64461.1 - 1.1 8.6 10.2 2.2 7.6 3.2 2.3 2 1 1 3 3 3 0 MAP7 (E-MAP-115) family Abhydrolase_6 PF12697.2 OAP64462.1 - 5.6e-27 95.0 0.0 3.3e-26 92.5 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Clr5 PF14420.1 OAP64462.1 - 2.5e-21 75.2 0.1 8.5e-21 73.6 0.1 2.0 1 0 0 1 1 1 1 Clr5 domain Abhydrolase_5 PF12695.2 OAP64462.1 - 6.4e-05 22.7 0.0 0.00016 21.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP64462.1 - 0.0028 17.2 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 OAP64462.1 - 0.042 12.3 0.0 0.079 11.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family Aldedh PF00171.17 OAP64463.1 - 1.4e-143 478.5 0.1 1.8e-143 478.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP64463.1 - 6.5e-06 25.1 0.0 3e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) FimP PF09766.4 OAP64464.1 - 0.089 11.8 4.7 0.099 11.6 3.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein HSP90 PF00183.13 OAP64464.1 - 0.17 10.2 1.3 0.18 10.1 0.9 1.2 1 0 0 1 1 1 0 Hsp90 protein RR_TM4-6 PF06459.7 OAP64464.1 - 2.7 7.8 7.8 2.9 7.6 5.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dehydratase_hem PF13816.1 OAP64465.1 - 3.2e-60 203.7 0.0 5e-60 203.1 0.0 1.3 1 1 0 1 1 1 1 Haem-containing dehydratase CN_hydrolase PF00795.17 OAP64466.1 - 1.4e-32 112.5 0.0 2.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sdh_cyt PF01127.17 OAP64467.1 - 2.6e-18 66.0 4.3 3.2e-18 65.7 3.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit APH PF01636.18 OAP64468.1 - 0.0026 17.5 1.1 0.0071 16.1 0.4 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DIOX_N PF14226.1 OAP64469.1 - 3.6e-33 114.5 0.0 2.5e-31 108.6 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP64469.1 - 8e-15 54.9 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD-oxidase_C PF02913.14 OAP64470.1 - 3.5e-59 200.1 0.2 5e-59 199.6 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAP64470.1 - 3.2e-39 133.5 0.0 6e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain ADH_N PF08240.7 OAP64471.1 - 1.1e-33 115.2 2.2 1.6e-33 114.7 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP64471.1 - 8.6e-26 90.0 0.3 1.5e-25 89.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 OAP64471.1 - 9.3e-06 25.3 0.3 1.9e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 OAP64471.1 - 3.5e-05 24.6 0.1 6.6e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAP64471.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 OAP64471.1 - 0.0032 18.0 0.1 0.0077 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain XdhC_C PF13478.1 OAP64471.1 - 0.023 15.0 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain PrmA PF06325.8 OAP64471.1 - 0.025 13.7 0.3 0.037 13.1 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Hydantoinase_A PF01968.13 OAP64471.1 - 0.029 13.4 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Met_10 PF02475.11 OAP64471.1 - 0.029 13.9 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.9 OAP64471.1 - 0.039 13.3 0.7 0.061 12.7 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase small domain DapB_N PF01113.15 OAP64471.1 - 0.049 13.5 0.3 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 OAP64471.1 - 0.057 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 OAP64471.1 - 0.087 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SGL PF08450.7 OAP64472.1 - 2.4e-20 72.9 0.3 2.5e-19 69.6 0.2 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 OAP64472.1 - 2.5e-05 24.2 0.0 0.00035 20.5 0.0 2.8 3 1 0 3 3 3 1 Strictosidine synthase PD40 PF07676.7 OAP64472.1 - 0.11 12.1 0.9 0.37 10.4 0.0 2.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Yae1_N PF09811.4 OAP64473.1 - 2.4e-06 26.9 1.8 6.2e-06 25.6 1.2 1.7 1 1 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.6 OAP64474.1 - 3.3e-141 470.4 0.0 4.4e-141 470.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAP64474.1 - 1.1e-07 30.3 0.1 4e-05 21.8 0.0 3.1 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) RNase_H2-Ydr279 PF09468.5 OAP64474.1 - 0.078 12.1 2.0 0.13 11.4 1.4 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Elongin_A PF06881.6 OAP64474.1 - 0.41 11.0 7.2 0.88 9.9 5.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DZR PF12773.2 OAP64474.1 - 0.62 9.9 5.3 1.7 8.5 3.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon DUF2201_N PF13203.1 OAP64474.1 - 2.3 7.3 7.9 3.7 6.6 5.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Ribosomal_L6e PF01159.14 OAP64474.1 - 5.7 7.2 6.3 14 6.0 4.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L6e Zn_clus PF00172.13 OAP64476.1 - 0.00068 19.4 0.8 0.0013 18.6 0.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Agouti PF05039.7 OAP64476.1 - 0.017 15.4 1.1 0.058 13.7 0.7 1.8 1 0 0 1 1 1 0 Agouti protein TauD PF02668.11 OAP64477.1 - 5e-20 72.2 0.0 7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CTP_transf_2 PF01467.21 OAP64478.1 - 1.3e-06 28.5 0.0 3.6e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase Cyclin_N PF00134.18 OAP64479.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain GlutR_dimer PF00745.15 OAP64479.1 - 0.27 11.1 1.9 2.8 7.9 0.0 2.7 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain WD40 PF00400.27 OAP64481.1 - 7.4e-25 85.8 4.2 1.2e-07 31.2 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat MMS1_N PF10433.4 OAP64481.1 - 0.031 12.4 0.0 0.07 11.2 0.0 1.6 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nup160 PF11715.3 OAP64481.1 - 0.062 11.4 0.1 0.21 9.6 0.0 1.7 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Kelch_5 PF13854.1 OAP64482.1 - 6.9e-24 83.3 0.3 4.7e-06 26.4 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 OAP64482.1 - 1e-21 76.1 2.2 4.4e-06 26.6 0.0 4.9 3 1 2 5 5 5 4 Kelch motif Kelch_4 PF13418.1 OAP64482.1 - 1.7e-21 75.7 5.7 7.6e-05 22.3 0.0 5.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 OAP64482.1 - 7.1e-20 70.6 6.6 8.2e-07 29.0 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 OAP64482.1 - 5.7e-19 67.0 1.9 1.3e-05 24.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 OAP64482.1 - 5e-16 57.9 0.3 3.7e-06 26.3 0.0 4.4 4 0 0 4 4 4 3 Kelch motif BTB PF00651.26 OAP64482.1 - 1.1e-10 41.4 0.1 2.2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 OAP64482.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch WD40 PF00400.27 OAP64483.1 - 7.5e-22 76.3 20.0 1.6e-06 27.7 0.1 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 OAP64483.1 - 9.3e-05 22.2 0.2 0.01 15.5 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 OAP64483.1 - 0.085 12.3 0.0 0.97 8.9 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Fer4_13 PF13370.1 OAP64484.1 - 0.15 12.4 2.0 1.3 9.4 0.0 3.3 3 2 1 4 4 4 0 4Fe-4S single cluster domain FliJ PF02050.11 OAP64485.1 - 0.012 15.6 0.2 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein zf-CCHC PF00098.18 OAP64486.1 - 3.4e-23 80.4 22.1 4.3e-09 35.8 1.5 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.1 OAP64486.1 - 6.6e-07 28.7 9.9 0.0016 17.9 0.0 3.2 2 1 1 3 3 3 3 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 OAP64486.1 - 6.1e-06 25.8 13.0 0.0079 15.9 0.3 3.1 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.1 OAP64486.1 - 0.00094 18.8 13.9 0.22 11.1 0.7 3.1 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.1 OAP64486.1 - 0.07 12.8 0.9 0.07 12.8 0.6 3.2 3 0 0 3 3 3 0 Zinc knuckle DZR PF12773.2 OAP64486.1 - 0.54 10.1 14.5 1.2e+02 2.5 10.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 OAP64486.1 - 3.3 7.6 14.9 9.8 6.1 0.5 2.9 2 1 0 2 2 2 0 IBR domain zf-TRAF PF02176.13 OAP64486.1 - 3.9 7.9 8.4 23 5.4 0.0 2.6 2 1 1 3 3 3 0 TRAF-type zinc finger UDPGP PF01704.13 OAP64487.1 - 1.9e-56 191.3 0.0 2.6e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pro_isomerase PF00160.16 OAP64488.1 - 4.9e-31 108.0 0.0 7.5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 OAP64488.1 - 2.9e-17 62.0 0.1 4.2e-16 58.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP64488.1 - 3.5e-12 46.1 0.1 9.9e-12 44.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP64488.1 - 1.6e-10 40.6 0.1 3e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAP64488.1 - 0.029 14.1 0.1 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Zn_clus PF00172.13 OAP64489.1 - 5.2e-06 26.2 3.9 5.2e-06 26.2 2.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.14 OAP64490.1 - 1.5e-34 117.6 0.1 2.3e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e DUF211 PF02680.9 OAP64490.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Methyltransf_16 PF10294.4 OAP64491.1 - 4.1e-20 71.9 0.0 6.4e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAP64491.1 - 0.00065 20.2 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAP64491.1 - 0.0052 15.9 0.1 0.012 14.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 OAP64491.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.11 OAP64491.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein HSP70 PF00012.15 OAP64492.1 - 1.5e-06 26.4 0.0 3e-05 22.1 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein HTH_29 PF13551.1 OAP64494.1 - 0.0015 18.6 0.1 0.0023 18.0 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix IncA PF04156.9 OAP64495.1 - 0.072 12.6 32.4 0.54 9.8 10.6 3.3 1 1 2 3 3 3 0 IncA protein HipA_C PF07804.7 OAP64495.1 - 0.14 12.3 0.1 0.46 10.6 0.1 1.9 1 0 0 1 1 1 0 HipA-like C-terminal domain Tropomyosin_1 PF12718.2 OAP64495.1 - 0.61 9.9 32.9 0.78 9.5 17.8 3.4 2 1 0 2 2 2 0 Tropomyosin like TMPIT PF07851.8 OAP64495.1 - 0.93 8.5 4.8 1.7 7.6 3.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.1 OAP64495.1 - 3.7 5.8 17.2 0.51 8.7 8.3 1.9 1 1 1 2 2 2 0 AAA domain DUF972 PF06156.8 OAP64495.1 - 6.1 7.2 20.6 4 7.8 3.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DivIVA PF05103.8 OAP64495.1 - 9.4 6.2 23.2 1.4 8.9 0.2 3.5 2 1 1 3 3 3 0 DivIVA protein DnaJ PF00226.26 OAP64496.1 - 1.6e-14 53.4 0.0 3.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Thg1C PF14413.1 OAP64497.1 - 0.032 13.9 5.5 27 4.4 3.8 3.3 1 1 0 1 1 1 0 Thg1 C terminal domain ParcG PF10274.4 OAP64497.1 - 0.72 9.7 8.5 40 4.0 0.4 3.9 1 1 4 5 5 5 0 Parkin co-regulated protein DNAPolymera_Pol PF11590.3 OAP64497.1 - 2.5 7.8 23.0 71 3.1 0.1 7.2 2 2 6 8 8 8 0 DNA polymerase catalytic subunit Pol Abhydrolase_3 PF07859.8 OAP64499.1 - 2.7e-50 170.8 0.0 3.6e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP64499.1 - 4.7e-06 26.6 0.2 8.4e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAP64499.1 - 0.00096 17.7 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) COesterase PF00135.23 OAP64499.1 - 0.0037 16.0 0.0 0.024 13.3 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 OAP64499.1 - 0.013 14.7 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAP64499.1 - 0.03 14.0 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.4 OAP64499.1 - 0.11 11.6 0.1 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF3328 PF11807.3 OAP64501.1 - 1.8e-34 119.3 0.0 2.2e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 OAP64502.1 - 8.4e-36 123.6 0.0 1.1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ank_2 PF12796.2 OAP64504.1 - 1.5e-34 118.1 4.0 5.8e-19 68.2 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP64504.1 - 9.7e-23 80.1 1.1 2.6e-11 43.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 OAP64504.1 - 2.2e-18 65.0 2.3 1.7e-09 37.0 0.4 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 OAP64504.1 - 9.5e-18 63.8 2.2 1.3e-08 34.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP64504.1 - 1.3e-14 52.8 0.6 2.4e-07 30.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Fungal_trans_2 PF11951.3 OAP64506.1 - 1.7e-06 26.9 0.2 2.5e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNApol3-delta_C PF09115.5 OAP64506.1 - 0.059 13.4 3.6 0.53 10.3 0.1 2.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal GFA PF04828.9 OAP64507.1 - 9.1e-15 54.3 1.6 9.1e-15 54.3 1.1 2.1 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Tyrosinase PF00264.15 OAP64508.1 - 3e-47 161.6 1.4 3.8e-47 161.2 1.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Ecm33 PF12454.3 OAP64508.1 - 0.17 11.7 0.8 0.55 10.1 0.1 2.1 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Pyr_redox_2 PF07992.9 OAP64510.1 - 5.9e-28 98.1 0.1 9.7e-28 97.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 OAP64510.1 - 1.8e-14 53.0 0.0 8.8e-14 50.8 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 OAP64510.1 - 4.2e-14 52.7 1.4 1.8e-13 50.6 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP64510.1 - 3e-08 33.9 0.0 3.6e-05 23.9 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 OAP64510.1 - 1.2e-06 28.1 0.0 2.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 OAP64510.1 - 1.2e-05 25.4 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Reductase C-terminal DUF1188 PF06690.6 OAP64510.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) K_oxygenase PF13434.1 OAP64510.1 - 0.031 13.2 0.0 0.17 10.8 0.0 1.9 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP64510.1 - 0.042 13.6 0.5 5.5 6.7 0.0 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.13 OAP64510.1 - 0.074 13.0 0.1 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain DUF2767 PF10965.3 OAP64510.1 - 0.51 10.2 2.3 1 9.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2767) SHS2_Rpb7-N PF03876.12 OAP64511.1 - 6.3e-05 23.0 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF1387 PF07139.6 OAP64511.1 - 0.01 15.4 2.7 0.01 15.4 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) MFS_1 PF07690.11 OAP64513.1 - 4.6e-20 71.6 37.4 6.5e-12 44.8 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP64513.1 - 0.0025 17.5 4.9 0.9 9.3 0.1 3.1 3 0 0 3 3 3 2 MFS_1 like family Acyl-CoA_dh_C PF12806.2 OAP64513.1 - 1.9 8.3 5.5 5.7 6.8 0.1 3.0 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like CrtC PF07143.6 OAP64514.1 - 1.4e-17 63.9 0.1 2e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) LSPR PF06049.7 OAP64514.1 - 0.12 11.8 1.3 2.3 8.0 0.2 2.8 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat TRI12 PF06609.8 OAP64515.1 - 6.7e-33 113.7 26.3 9.2e-33 113.2 18.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP64515.1 - 2.4e-22 79.1 47.8 2.4e-22 79.1 33.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3735 PF12537.3 OAP64515.1 - 4.8 7.2 5.8 6.5 6.8 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) Abhydrolase_3 PF07859.8 OAP64516.1 - 4.3e-45 153.8 0.0 6.1e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP64516.1 - 2e-07 30.1 0.0 5.2e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2236 PF09995.4 OAP64517.1 - 3.2e-12 46.2 2.4 3.2e-12 46.2 1.7 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3425 PF11905.3 OAP64518.1 - 1.4e-14 54.1 0.4 2.8e-14 53.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP64518.1 - 5.5e-05 23.0 1.9 9.7e-05 22.2 1.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor ABC_tran_2 PF12848.2 OAP64518.1 - 0.026 14.3 0.6 0.055 13.3 0.4 1.5 1 0 0 1 1 1 0 ABC transporter CDC45 PF02724.9 OAP64519.1 - 0.38 8.7 5.3 0.39 8.6 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CLTH PF10607.4 OAP64520.1 - 4.3e-26 91.3 0.0 6.5e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 OAP64520.1 - 7.3e-24 84.2 0.1 1.2e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 OAP64520.1 - 0.00091 18.9 0.1 0.00091 18.9 0.0 2.1 3 0 0 3 3 3 1 LisH INO80_Ies4 PF08193.6 OAP64521.1 - 6.1e-60 202.9 21.4 8.7e-60 202.4 14.8 1.3 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Mei5 PF10376.4 OAP64522.1 - 6.8e-06 25.7 2.3 9.1e-06 25.3 1.6 1.2 1 0 0 1 1 1 1 Double-strand recombination repair protein DnaG_DnaB_bind PF08278.6 OAP64522.1 - 0.015 15.4 2.7 0.022 15.0 1.9 1.2 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Hanta_nucleocap PF00846.13 OAP64522.1 - 0.036 12.7 0.9 0.04 12.6 0.6 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein FUSC PF04632.7 OAP64522.1 - 0.061 11.7 4.6 0.076 11.4 3.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Epimerase PF01370.16 OAP64523.1 - 1.1e-14 54.4 0.0 2.2e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 OAP64523.1 - 2.4e-07 29.9 0.0 0.00033 19.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 OAP64523.1 - 9.2e-06 25.7 0.0 3.7e-05 23.8 0.0 2.0 3 0 0 3 3 3 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP64523.1 - 1.7e-05 23.7 0.0 3.1e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAP64523.1 - 7e-05 22.8 0.2 0.00019 21.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAP64523.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 OAP64523.1 - 0.025 13.5 0.0 0.044 12.7 0.0 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 OAP64523.1 - 0.032 13.1 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 OAP64523.1 - 0.14 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Arf PF00025.16 OAP64524.1 - 7.1e-39 132.8 0.3 5.8e-24 84.2 0.4 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 OAP64524.1 - 1.3e-12 47.1 0.0 1.3e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 OAP64524.1 - 4.9e-08 32.5 0.1 0.00011 21.6 0.0 2.8 2 1 0 2 2 2 2 Ras family Miro PF08477.8 OAP64524.1 - 6.1e-07 29.9 0.0 3.4e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 OAP64524.1 - 2.2e-06 27.0 0.4 4.6e-05 22.7 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 OAP64524.1 - 2.8e-06 27.2 0.0 7.9e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAP64524.1 - 3.7e-06 26.5 0.0 0.0025 17.2 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAP64524.1 - 0.00028 20.0 0.0 0.00057 19.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 OAP64524.1 - 0.019 14.2 0.2 0.059 12.6 0.1 1.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Fungal_trans_2 PF11951.3 OAP64525.1 - 6.5e-47 159.9 2.4 7.9e-47 159.6 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64525.1 - 1.5e-10 40.7 4.7 2.8e-10 39.9 3.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_N PF00339.24 OAP64526.1 - 7.3e-12 45.3 0.5 1.5e-08 34.5 0.0 3.4 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 OAP64526.1 - 0.033 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus DUF221 PF02714.10 OAP64527.1 - 1.9e-100 335.9 21.3 3e-100 335.2 14.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAP64527.1 - 9e-38 129.2 2.1 9e-38 129.2 1.5 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 OAP64527.1 - 3.5e-20 71.6 0.1 6.3e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 OAP64527.1 - 4.1e-09 36.8 0.1 8.4e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 OAP64527.1 - 0.042 13.4 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dor1 PF04124.7 OAP64527.1 - 0.093 11.1 0.0 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 Dor1-like family DUF3988 PF13149.1 OAP64528.1 - 2.9 7.3 8.9 1.4 8.3 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3988) Pyr_redox_3 PF13738.1 OAP64529.1 - 2.1e-19 70.4 0.0 9.1e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP64529.1 - 3.5e-11 42.0 0.0 6e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP64529.1 - 1.4e-08 34.0 0.0 1.9e-07 30.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAP64529.1 - 1.7e-05 24.6 0.0 0.0044 16.8 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP64529.1 - 0.00019 21.3 2.5 0.028 14.3 1.1 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP64529.1 - 0.051 13.5 0.1 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP64529.1 - 0.17 10.3 0.0 5.4 5.3 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein Sugar_tr PF00083.19 OAP64530.1 - 3.7e-81 273.0 22.0 4.3e-81 272.7 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64530.1 - 3.8e-26 91.6 31.5 5.5e-20 71.3 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP64530.1 - 0.26 9.4 11.1 0.026 12.7 3.6 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 OAP64530.1 - 0.59 8.4 37.0 0.69 8.2 7.3 3.6 2 2 1 3 3 3 0 MFS/sugar transport protein MFS_1 PF07690.11 OAP64531.1 - 5.2e-25 87.9 40.1 5.2e-25 87.9 27.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_tranf_2_3 PF13641.1 OAP64532.1 - 1.3e-33 116.6 0.0 2.1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAP64532.1 - 1e-21 77.5 0.3 1e-21 77.5 0.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 OAP64532.1 - 1.3e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 OAP64532.1 - 2.8e-11 42.4 0.2 3.7e-05 22.2 0.2 2.9 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.1 OAP64532.1 - 3.6e-11 42.6 0.0 6.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Dimeth_Pyl PF09505.5 OAP64532.1 - 0.12 10.5 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Chitin_synth_2 PF03142.10 OAP64532.1 - 0.13 10.6 0.4 1.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Chitin synthase TauD PF02668.11 OAP64533.1 - 1.2e-55 188.9 0.1 1.5e-55 188.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 OAP64534.1 - 9e-37 126.5 11.5 9e-37 126.5 8.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 OAP64534.1 - 0.057 13.4 5.0 0.48 10.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) FMO-like PF00743.14 OAP64535.1 - 1e-40 139.4 0.0 1e-20 73.4 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAP64535.1 - 2.2e-17 63.8 1.6 2.7e-15 57.0 0.6 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP64535.1 - 1.9e-10 40.7 2.5 7.8e-05 22.4 0.1 3.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 OAP64535.1 - 3.9e-10 39.1 7.1 1.7e-07 30.4 2.7 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP64535.1 - 5.8e-10 39.3 0.0 7.9e-08 32.4 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP64535.1 - 5.3e-08 32.7 0.5 2.4e-07 30.6 0.0 2.4 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP64535.1 - 7.1e-07 28.4 0.6 0.00012 21.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 OAP64535.1 - 1.6e-06 27.5 0.1 0.017 14.2 0.1 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 OAP64535.1 - 0.00014 21.1 3.2 0.00067 18.8 2.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAP64535.1 - 0.00041 19.5 0.3 0.00076 18.6 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAP64535.1 - 0.00051 19.0 0.1 0.0044 15.9 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.15 OAP64535.1 - 0.0013 18.8 0.1 0.2 11.7 0.2 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 OAP64535.1 - 0.0044 15.5 1.5 0.02 13.3 0.8 2.1 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.13 OAP64535.1 - 0.012 15.2 2.2 0.018 14.7 0.9 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 OAP64535.1 - 0.012 14.6 2.4 0.018 14.1 0.5 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 OAP64535.1 - 0.015 15.6 0.9 0.015 15.6 0.6 3.0 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 OAP64535.1 - 0.03 14.1 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 OAP64535.1 - 0.036 12.9 0.6 0.084 11.7 0.5 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.7 OAP64535.1 - 0.051 12.9 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain MFS_1 PF07690.11 OAP64537.1 - 1e-14 54.0 14.5 1e-14 54.0 10.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MARVEL PF01284.18 OAP64538.1 - 1.5e-07 31.3 12.1 3.8e-07 30.0 8.4 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF3561 PF12084.3 OAP64538.1 - 0.027 14.3 3.5 0.043 13.6 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) 7TMR-DISM_7TM PF07695.6 OAP64538.1 - 0.68 9.5 10.3 0.58 9.7 5.0 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF2306 PF10067.4 OAP64538.1 - 4.8 7.3 7.1 0.92 9.6 1.6 2.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Methyltransf_23 PF13489.1 OAP64539.1 - 1.4e-08 34.5 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP64539.1 - 8e-06 26.4 0.1 0.00016 22.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP64539.1 - 7e-05 23.2 0.0 0.00018 21.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP64539.1 - 0.00013 22.4 0.0 0.00023 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP64539.1 - 0.012 15.2 0.0 0.13 11.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Waikav_capsid_1 PF12264.3 OAP64539.1 - 0.045 13.0 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Methyltransf_31 PF13847.1 OAP64540.1 - 1.4e-09 37.7 0.0 7.1e-09 35.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP64540.1 - 2.8e-08 33.6 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP64540.1 - 1.3e-07 32.1 0.0 4.2e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP64540.1 - 3.2e-06 27.5 0.0 7.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP64540.1 - 0.0001 22.7 0.0 0.00032 21.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 OAP64540.1 - 0.00018 20.8 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.13 OAP64540.1 - 0.03 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 OAP64540.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain GFA PF04828.9 OAP64541.1 - 4.7e-17 61.7 0.1 4.7e-17 61.7 0.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-UBR PF02207.15 OAP64541.1 - 5.2 6.8 11.0 16 5.3 0.3 3.1 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) MNHE PF01899.11 OAP64542.1 - 0.089 12.4 2.1 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit TcpE PF12648.2 OAP64542.1 - 6.1 7.0 6.2 1.5 9.0 0.1 2.8 3 0 0 3 3 3 0 TcpE family SSP160 PF06933.6 OAP64542.1 - 6.1 4.6 9.0 8.5 4.2 6.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1900 PF08954.6 OAP64543.1 - 2.9e-49 166.0 0.0 8.8e-49 164.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 OAP64543.1 - 2.1e-34 116.9 0.0 3.9e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 OAP64543.1 - 5.4e-24 83.1 1.7 6.9e-07 28.9 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat BRE1 PF08647.6 OAP64543.1 - 0.077 12.9 0.9 0.15 12.0 0.6 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.6 OAP64543.1 - 0.17 11.7 2.3 0.33 10.8 0.8 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Striatin PF08232.7 OAP64544.1 - 0.081 13.2 1.3 0.099 12.9 0.7 1.3 1 1 0 1 1 1 0 Striatin family APH PF01636.18 OAP64545.1 - 2.8e-11 43.6 0.9 2.3e-10 40.6 0.0 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 OAP64546.1 - 1e-68 231.2 0.0 1.2e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 OAP64546.1 - 0.044 13.9 0.0 15 5.7 0.0 2.6 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase F_actin_cap_B PF01115.12 OAP64547.1 - 2.7e-99 331.2 0.0 3.1e-99 331.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Fungal_trans PF04082.13 OAP64548.1 - 5.8e-15 54.8 2.2 8.4e-15 54.3 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64548.1 - 7.1e-10 38.6 8.4 7.1e-10 38.6 5.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LAT PF15234.1 OAP64549.1 - 0.035 13.5 1.6 0.056 12.9 1.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells NOA36 PF06524.7 OAP64549.1 - 0.088 12.0 2.5 0.12 11.5 1.7 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 OAP64549.1 - 0.093 12.2 2.8 0.15 11.5 1.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAP64549.1 - 0.14 11.7 3.7 0.27 10.8 2.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 OAP64549.1 - 0.45 10.8 6.8 0.78 10.0 4.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 OAP64549.1 - 1.3 7.8 4.7 1.9 7.3 3.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Patatin PF01734.17 OAP64551.1 - 1.3e-20 74.1 0.1 3.1e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.1 OAP64551.1 - 0.0013 18.3 3.3 0.0028 17.3 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP64551.1 - 0.002 18.1 6.4 0.005 16.8 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.18 OAP64551.1 - 0.0026 17.6 0.0 0.093 12.6 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-C3HC4 PF00097.20 OAP64551.1 - 0.0034 17.0 5.0 0.0083 15.7 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_29 PF13555.1 OAP64551.1 - 0.0055 16.2 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAP64551.1 - 0.011 15.6 0.1 0.038 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain zf-RING_UBOX PF13445.1 OAP64551.1 - 0.016 14.9 0.3 0.051 13.3 0.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DUF258 PF03193.11 OAP64551.1 - 0.02 14.0 0.0 0.091 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 zf-RING_2 PF13639.1 OAP64551.1 - 0.036 13.8 6.9 0.089 12.6 4.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 OAP64551.1 - 0.04 13.6 5.8 0.11 12.2 4.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain ABC_tran PF00005.22 OAP64551.1 - 0.067 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter zf-C3HC4_4 PF15227.1 OAP64551.1 - 2.4 8.1 6.9 6.7 6.6 4.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING AA_permease PF00324.16 OAP64552.1 - 8.6e-70 235.3 29.7 1.8e-67 227.7 17.1 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 OAP64552.1 - 8.7e-27 93.7 33.7 1.5e-26 92.9 23.0 1.6 1 1 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.1 OAP64554.1 - 6.7e-20 71.8 0.1 1.2e-19 71.0 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP64554.1 - 3.2e-17 62.9 0.4 5.7e-17 62.1 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP64554.1 - 0.00014 21.6 0.4 0.00029 20.5 0.3 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAP64554.1 - 0.043 12.7 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3402 PF11882.3 OAP64555.1 - 9.7e-133 443.1 0.0 1.7e-132 442.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 OAP64555.1 - 2.6e-73 246.4 0.7 3.4e-73 246.0 0.0 1.5 2 0 0 2 2 2 1 N1221-like protein Fungal_trans_2 PF11951.3 OAP64556.1 - 4.1e-36 124.4 6.2 5.2e-36 124.0 4.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64556.1 - 6e-06 26.0 7.3 1.5e-05 24.8 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 OAP64556.1 - 0.83 9.8 8.8 2.2 8.5 6.1 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Aminotran_3 PF00202.16 OAP64557.1 - 8e-62 209.0 0.0 1.1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 OAP64557.1 - 0.037 13.1 0.0 0.14 11.2 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase Amidase PF01425.16 OAP64558.1 - 5e-95 318.9 0.0 5.9e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Amidase UNC-93 PF05978.11 OAP64559.1 - 2.6e-09 36.7 1.3 2.6e-09 36.7 0.9 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 OAP64559.1 - 2.5e-07 29.7 25.8 2.5e-07 29.7 17.9 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Med11 PF10280.4 OAP64560.1 - 1.4e-22 79.9 0.0 1.8e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF3813 PF12758.2 OAP64560.1 - 2.1 8.5 5.8 3.8 7.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) WD40 PF00400.27 OAP64561.1 - 3.9e-51 169.1 24.9 1.1e-09 37.8 0.6 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 OAP64561.1 - 1.4e-39 135.4 0.2 2.1e-39 134.8 0.2 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nucleoporin_N PF08801.6 OAP64561.1 - 1.9e-05 23.6 0.1 1 8.0 0.0 4.7 3 1 2 5 5 5 1 Nup133 N terminal like eIF2A PF08662.6 OAP64561.1 - 0.0018 18.0 0.1 0.004 16.8 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 OAP64561.1 - 0.0019 17.9 0.1 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 LisH Nup160 PF11715.3 OAP64561.1 - 0.026 12.6 3.8 0.093 10.8 0.1 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Rhomboid PF01694.17 OAP64562.1 - 1.2e-18 67.5 3.8 1.4e-18 67.2 2.6 1.1 1 0 0 1 1 1 1 Rhomboid family DUF3353 PF11833.3 OAP64562.1 - 0.00098 18.6 1.2 0.0014 18.1 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3353) HDA2-3 PF11496.3 OAP64563.1 - 4.6e-17 61.7 0.2 4.6e-17 61.7 0.1 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 FMO-like PF00743.14 OAP64564.1 - 6.1e-44 150.1 0.0 5.5e-29 100.7 0.0 3.0 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAP64564.1 - 7.9e-18 65.2 0.1 1.2e-16 61.3 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP64564.1 - 3.2e-10 39.9 0.1 3.7e-08 33.3 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP64564.1 - 3.3e-09 36.8 0.0 4.5e-08 33.2 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP64564.1 - 3.5e-09 36.0 0.1 2e-06 26.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAP64564.1 - 9.8e-06 24.6 0.2 0.016 14.1 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP64564.1 - 4.4e-05 23.4 0.1 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAP64564.1 - 0.00036 19.7 0.4 0.065 12.3 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.22 OAP64564.1 - 0.0021 18.4 1.5 0.2 12.0 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP64564.1 - 0.0049 15.3 0.1 0.23 9.8 0.1 2.8 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.1 OAP64564.1 - 0.077 13.2 0.1 9.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 OAP64564.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Abhydrolase_5 PF12695.2 OAP64565.1 - 1.4e-18 67.0 1.1 2.2e-18 66.4 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP64565.1 - 2.1e-05 24.5 1.9 0.016 15.1 0.0 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 OAP64565.1 - 0.022 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.13 OAP64565.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Herpes_gE PF02480.11 OAP64566.1 - 0.11 10.7 0.2 0.11 10.6 0.1 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PhzC-PhzF PF02567.11 OAP64569.1 - 6.4e-38 130.5 0.0 9.6e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 OAP64569.1 - 0.0031 16.3 0.0 0.0056 15.5 0.0 1.4 1 0 0 1 1 1 1 Proline racemase CMD PF02627.15 OAP64570.1 - 3.5e-05 23.5 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family UPF0061 PF02696.9 OAP64571.1 - 1.1e-115 386.7 0.0 1.4e-115 386.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DrrA_P4M PF14860.1 OAP64571.1 - 0.11 12.2 0.2 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Myosin_tail_1 PF01576.14 OAP64572.1 - 0.00012 20.0 122.9 0.00012 20.0 85.2 6.7 1 1 5 6 6 6 4 Myosin tail GAS PF13851.1 OAP64572.1 - 0.00038 19.6 288.3 0.0044 16.2 10.9 14.7 1 1 10 13 13 13 8 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 OAP64572.1 - 0.00066 18.2 49.1 0.00066 18.2 34.1 9.1 1 1 7 8 8 8 2 Weak chloroplast movement under blue light Atg14 PF10186.4 OAP64572.1 - 0.00076 18.5 12.8 0.00076 18.5 8.9 13.6 1 1 13 14 14 14 2 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 OAP64572.1 - 0.00098 19.2 8.5 0.00098 19.2 5.9 17.0 6 3 9 18 18 18 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.16 OAP64572.1 - 0.004 16.6 297.5 0.041 13.3 34.0 9.8 1 1 7 9 9 9 5 Intermediate filament protein Fib_alpha PF08702.5 OAP64572.1 - 0.0055 16.8 4.7 0.0055 16.8 3.3 14.6 1 1 12 15 15 15 3 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 OAP64572.1 - 0.039 12.4 259.5 0.017 13.6 1.2 9.5 1 1 6 8 8 8 0 AAA domain Amidohydro_2 PF04909.9 OAP64573.1 - 2.5e-37 128.9 0.0 3.2e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 OAP64574.1 - 2.5e-22 79.0 0.1 3.9e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64574.1 - 1.8e-05 24.5 9.9 3.1e-05 23.8 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 OAP64575.1 - 2e-82 277.1 29.4 2.4e-82 276.9 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64575.1 - 1.9e-16 59.7 40.7 1.4e-11 43.7 14.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_14 PF13428.1 OAP64575.1 - 0.11 13.1 0.1 0.26 12.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Dabb PF07876.7 OAP64576.1 - 7.7e-18 64.7 0.3 8.9e-18 64.5 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain PhyH PF05721.8 OAP64578.1 - 2.8e-11 43.8 0.0 4.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Acyl_transf_3 PF01757.17 OAP64579.1 - 9.2e-27 93.7 32.0 1.5e-26 93.0 22.2 1.3 1 1 0 1 1 1 1 Acyltransferase family Stimulus_sens_1 PF13756.1 OAP64579.1 - 0.0028 18.0 0.1 0.011 16.1 0.1 2.0 2 1 0 2 2 2 1 Stimulus-sensing domain Meth_synt_2 PF01717.13 OAP64580.1 - 3.4e-14 52.5 0.0 8.5e-14 51.2 0.0 1.6 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 OAP64580.1 - 2.1e-08 33.8 0.0 0.00076 18.8 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain RTA1 PF04479.8 OAP64581.1 - 0.00043 19.8 6.0 0.00089 18.7 4.2 1.6 1 1 0 1 1 1 1 RTA1 like protein bZIP_1 PF00170.16 OAP64583.1 - 7.7e-05 22.5 13.5 0.00012 21.9 8.9 1.6 1 1 1 2 2 2 1 bZIP transcription factor GAS PF13851.1 OAP64583.1 - 0.00038 19.6 3.3 0.00046 19.4 2.3 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 OAP64583.1 - 0.0032 17.3 3.4 0.0041 16.9 2.4 1.1 1 0 0 1 1 1 1 Tropomyosin like bZIP_2 PF07716.10 OAP64583.1 - 0.016 15.0 9.0 0.016 15.0 6.2 2.0 2 0 0 2 2 2 0 Basic region leucine zipper DUF3450 PF11932.3 OAP64583.1 - 0.087 12.0 2.6 0.11 11.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 OAP64583.1 - 0.26 10.8 5.1 0.35 10.4 3.5 1.2 1 0 0 1 1 1 0 IncA protein DUF4633 PF15464.1 OAP64583.1 - 0.55 10.0 4.6 1.3 8.8 3.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4633) DUF479 PF04336.7 OAP64583.1 - 0.7 10.0 3.7 15 5.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF479 bZIP_Maf PF03131.12 OAP64583.1 - 0.74 10.1 12.4 1.1 9.5 8.0 1.7 1 1 1 2 2 2 0 bZIP Maf transcription factor PIG-P PF08510.7 OAP64584.1 - 1.2e-42 144.5 1.4 3.1e-42 143.1 0.1 2.3 2 1 0 2 2 2 1 PIG-P Peptidase_S28 PF05577.7 OAP64586.1 - 2.1e-46 158.3 0.4 1.4e-37 129.3 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 RE_R_Pab1 PF09522.5 OAP64586.1 - 0.23 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease adh_short PF00106.20 OAP64587.1 - 1.5e-19 70.5 0.9 1.5e-19 70.5 0.6 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64587.1 - 5.2e-14 52.6 0.5 1.2e-12 48.1 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64587.1 - 1.6e-08 34.4 0.3 4.1e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 KR domain p450 PF00067.17 OAP64588.1 - 2.4e-55 187.8 0.0 2.8e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL PF07366.7 OAP64589.1 - 0.0051 16.4 0.3 0.019 14.5 0.1 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 OAP64589.1 - 0.13 12.7 0.4 2.1 8.8 0.3 2.1 1 1 0 1 1 1 0 SnoaL-like domain FAD_binding_3 PF01494.14 OAP64590.1 - 1.8e-64 218.0 0.0 2.8e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP64590.1 - 0.004 16.1 0.0 0.017 14.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP64590.1 - 0.007 16.7 0.0 0.032 14.6 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.7 OAP64590.1 - 0.024 14.2 0.1 0.096 12.2 0.1 2.0 1 1 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 OAP64590.1 - 0.039 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP64590.1 - 0.073 11.9 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Amidohydro_4 PF13147.1 OAP64591.1 - 5.7e-26 92.1 0.0 7.1e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 OAP64591.1 - 3.4e-15 55.6 0.4 1.4e-14 53.6 0.0 2.2 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 OAP64591.1 - 8.8e-13 48.5 0.0 5.7e-11 42.6 0.0 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 OAP64591.1 - 0.00015 21.1 0.1 0.44 9.7 0.0 3.0 3 1 0 3 3 3 2 Amidohydrolase family Usp PF00582.21 OAP64591.1 - 0.13 12.4 0.1 0.35 11.0 0.1 1.7 1 0 0 1 1 1 0 Universal stress protein family 2OG-FeII_Oxy PF03171.15 OAP64593.1 - 4.9e-14 52.4 0.0 7.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP64593.1 - 3.4e-08 34.0 0.0 6.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sugar_tr PF00083.19 OAP64594.1 - 6e-84 282.2 17.2 7.3e-84 281.9 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64594.1 - 1.4e-29 102.9 19.2 1.4e-29 102.9 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PARP PF00644.15 OAP64595.1 - 0.0035 16.7 0.1 0.0048 16.3 0.1 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ABA_WDS PF02496.11 OAP64595.1 - 0.013 15.6 5.9 0.013 15.6 4.1 3.2 2 2 1 3 3 3 0 ABA/WDS induced protein SelP_N PF04592.9 OAP64595.1 - 0.014 14.7 5.4 0.014 14.7 3.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 OAP64595.1 - 0.029 13.4 4.9 0.029 13.3 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.11 OAP64595.1 - 0.1 11.8 0.8 0.13 11.5 0.6 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein SLAIN PF15301.1 OAP64595.1 - 0.13 11.4 1.4 0.16 11.1 1.0 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family DUF755 PF05501.6 OAP64595.1 - 1.2 9.2 5.9 1.8 8.6 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) HSP20 PF00011.16 OAP64596.1 - 1.3e-11 44.2 0.0 1.8e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family HR_lesion PF05514.6 OAP64598.1 - 0.045 13.5 1.0 0.053 13.3 0.7 1.1 1 0 0 1 1 1 0 HR-like lesion-inducing UPF0197 PF05251.7 OAP64598.1 - 0.58 10.4 6.5 2 8.7 4.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) Tetraspannin PF00335.15 OAP64598.1 - 0.6 9.3 3.0 0.73 9.0 2.1 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF1459 PF07312.6 OAP64598.1 - 0.78 9.7 4.2 0.42 10.5 1.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1459) YrhK PF14145.1 OAP64598.1 - 1.7 8.3 8.7 66 3.2 6.0 2.3 1 1 0 1 1 1 0 YrhK-like protein DUF2985 PF11204.3 OAP64599.1 - 9.1e-28 95.8 2.0 2.5e-27 94.4 1.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Dicty_REP PF05086.7 OAP64599.1 - 1.8 6.2 6.2 2.9 5.5 4.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PhyH PF05721.8 OAP64600.1 - 3.2e-27 95.9 0.0 4.3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UDPG_MGDP_dh_N PF03721.9 OAP64601.1 - 9.7e-44 148.9 0.0 1.8e-27 95.9 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 OAP64601.1 - 4.9e-31 106.8 0.0 9.4e-31 105.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 OAP64601.1 - 6.3e-22 77.7 0.0 1.5e-18 66.8 0.0 2.5 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 OAP64601.1 - 0.00047 19.9 0.1 2.6 7.7 0.0 3.4 3 1 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 OAP64601.1 - 0.0051 16.2 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Cellsynth_D PF03500.8 OAP64601.1 - 0.0076 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Cellulose synthase subunit D NAD_binding_2 PF03446.10 OAP64601.1 - 0.015 15.1 0.0 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 OAP64601.1 - 0.04 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 OAP64601.1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.15 OAP64602.1 - 4.4e-35 120.6 0.0 6.5e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAP64602.1 - 6.2e-14 52.3 0.0 1.5e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAP64602.1 - 1.6e-12 47.8 0.6 4.1e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 OAP64602.1 - 1.6e-09 37.9 0.0 4.2e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAP64602.1 - 6.8e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 OAP64602.1 - 0.016 15.0 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like Strep_his_triad PF04270.8 OAP64602.1 - 0.031 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Streptococcal histidine triad protein GlgS PF08971.6 OAP64602.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Glycogen synthesis protein Fungal_trans_2 PF11951.3 OAP64603.1 - 1.3e-13 50.2 0.1 2.3e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tau95 PF09734.4 OAP64604.1 - 2e-24 86.5 0.0 2.3e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 OAP64605.1 - 3.3e-173 576.0 8.8 4.1e-173 575.6 6.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FAT PF02259.18 OAP64606.1 - 4e-74 249.7 8.6 4e-74 249.7 5.9 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 OAP64606.1 - 5.4e-23 81.6 0.9 3.2e-22 79.1 0.0 2.8 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 OAP64606.1 - 3.3e-07 29.6 0.0 7.3e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 OAP64607.1 - 5.5e-23 80.4 21.0 1.1e-06 28.1 0.0 8.3 6 2 0 7 7 7 4 TPR repeat Apc3 PF12895.2 OAP64607.1 - 4.3e-22 78.0 17.7 2e-18 66.2 0.8 5.7 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 OAP64607.1 - 2.1e-20 70.9 21.2 0.0085 15.9 0.1 9.6 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 OAP64607.1 - 1.4e-19 68.8 11.0 0.0027 17.2 0.1 8.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAP64607.1 - 5.4e-19 67.8 23.5 7.9e-09 35.3 0.1 8.2 6 2 1 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAP64607.1 - 4e-15 55.9 10.8 0.0084 16.4 0.2 6.1 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAP64607.1 - 2.9e-13 49.1 13.9 0.052 14.1 0.2 9.5 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAP64607.1 - 6.4e-11 42.6 25.2 0.0087 16.7 2.2 8.0 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAP64607.1 - 4.8e-10 38.4 3.4 1.1 9.2 0.0 6.9 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAP64607.1 - 1.8e-09 36.7 7.6 1.5 8.8 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAP64607.1 - 2.6e-07 30.6 7.1 0.42 11.1 0.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAP64607.1 - 2.3e-06 27.3 15.2 0.0047 16.8 0.1 7.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAP64607.1 - 5.7e-05 22.9 1.6 2.4 8.5 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAP64607.1 - 0.00024 21.2 16.6 0.077 13.4 0.1 5.8 5 0 0 5 5 4 2 Tetratricopeptide repeat PPR_3 PF13812.1 OAP64607.1 - 0.097 13.0 1.3 19 5.8 0.0 4.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR PF01535.15 OAP64607.1 - 0.43 10.6 1.7 20 5.4 0.0 3.6 4 0 0 4 4 4 0 PPR repeat Fis1_TPR_C PF14853.1 OAP64607.1 - 1.5 8.7 8.5 8.2 6.3 0.4 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF572 PF04502.8 OAP64608.1 - 4e-71 239.8 15.8 4.6e-71 239.6 11.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 OAP64608.1 - 0.029 14.2 1.0 0.082 12.7 0.7 1.6 1 1 0 1 1 1 0 Benyvirus 14KDa protein zf-FCS PF06467.9 OAP64608.1 - 0.53 9.9 3.2 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif T2SF PF00482.18 OAP64608.1 - 0.63 9.9 2.7 1.2 9.0 1.8 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F TF_Zn_Ribbon PF08271.7 OAP64608.1 - 4.2 6.7 6.3 3.2 7.1 1.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding adh_short PF00106.20 OAP64609.1 - 7.7e-25 87.7 0.1 1.8e-24 86.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64609.1 - 4.5e-15 56.0 0.0 5.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64609.1 - 9.8e-09 35.1 0.0 2.9e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP64609.1 - 1.3e-05 24.7 0.0 2.4e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP64609.1 - 6.7e-05 22.9 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 OAP64609.1 - 0.0011 17.8 0.1 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 OAP64609.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 OAP64609.1 - 0.074 12.8 0.1 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CHAD PF05235.9 OAP64609.1 - 0.11 12.0 0.1 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 CHAD domain Polysacc_synt_C PF14667.1 OAP64611.1 - 0.1 12.4 0.4 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain GST_N_3 PF13417.1 OAP64612.1 - 6.3e-15 55.1 0.0 1.9e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP64612.1 - 2.5e-14 52.9 0.0 5.8e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAP64612.1 - 2e-10 40.6 0.0 3.1e-08 33.6 0.0 2.9 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 OAP64612.1 - 2.1e-05 24.4 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thi4 PF01946.12 OAP64613.1 - 1.5e-106 354.6 0.0 1.8e-106 354.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 OAP64613.1 - 7.2e-09 35.0 0.3 4.5e-08 32.4 0.2 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP64613.1 - 2.4e-06 26.7 0.4 9.1e-06 24.8 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP64613.1 - 5e-06 26.4 0.3 1.5e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP64613.1 - 4.3e-05 23.4 0.3 0.00012 22.0 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP64613.1 - 5e-05 22.3 1.5 0.0033 16.3 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 OAP64613.1 - 0.00019 21.5 0.0 0.00028 21.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP64613.1 - 0.0002 21.1 1.6 0.0003 20.5 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 OAP64613.1 - 0.0045 16.1 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAP64613.1 - 0.015 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 OAP64613.1 - 0.05 12.0 0.2 0.07 11.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 OAP64613.1 - 0.11 11.0 0.2 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.11 OAP64614.1 - 1.3e-39 135.9 44.3 3.2e-39 134.6 30.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Mpv17_PMP22 PF04117.7 OAP64616.1 - 2.4e-17 62.2 0.3 4.3e-17 61.5 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ECH PF00378.15 OAP64617.1 - 2.1e-48 164.6 0.0 2.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 OAP64617.1 - 0.0084 15.8 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S49 PfkB PF00294.19 OAP64618.1 - 1.2e-36 126.3 0.1 1.5e-36 126.0 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Caleosin PF05042.8 OAP64619.1 - 8.4e-47 158.9 0.0 1e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.27 OAP64619.1 - 0.0013 17.9 1.7 0.4 10.0 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 OAP64619.1 - 0.0027 17.7 0.1 0.2 11.7 0.1 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 OAP64619.1 - 0.006 16.3 6.5 0.0068 16.2 0.5 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 OAP64619.1 - 0.0087 15.3 2.7 0.15 11.4 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 OAP64619.1 - 0.072 12.7 0.1 4 7.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair CAP PF00188.21 OAP64620.1 - 1.1e-18 67.8 1.1 2e-18 67.0 0.8 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF605 PF04652.11 OAP64620.1 - 0.46 9.8 8.8 0.56 9.5 6.1 1.1 1 0 0 1 1 1 0 Vta1 like Carn_acyltransf PF00755.15 OAP64621.1 - 1.7e-164 548.2 0.0 2.2e-150 501.5 0.0 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase JmjC PF02373.17 OAP64622.1 - 1e-35 122.4 0.4 2.7e-35 121.0 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 OAP64622.1 - 2.8e-19 69.1 8.7 6.1e-19 68.0 6.0 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAP64622.1 - 7.5e-18 64.4 7.4 7.5e-18 64.4 5.1 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 OAP64622.1 - 1.3e-09 37.4 0.2 3.8e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 jmjN domain RNA_pol_Rpb2_3 PF04565.11 OAP64622.1 - 0.14 11.9 0.1 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 APH PF01636.18 OAP64623.1 - 5.9e-09 36.0 0.0 5.1e-08 32.9 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 OAP64623.1 - 0.017 13.8 0.0 0.55 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF605 PF04652.11 OAP64624.1 - 8.5 5.6 11.1 12 5.1 7.7 1.1 1 0 0 1 1 1 0 Vta1 like TPR_12 PF13424.1 OAP64625.1 - 0.00042 20.1 1.5 0.0047 16.8 1.0 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAP64625.1 - 0.0051 16.5 1.1 2.7 7.9 0.1 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAP64625.1 - 0.025 14.4 2.6 2.9 7.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP64625.1 - 0.044 13.6 0.5 6.5 6.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAP64625.1 - 0.076 13.6 7.9 0.16 12.6 0.2 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAP64625.1 - 0.093 12.3 0.6 0.45 10.1 0.2 2.1 1 1 1 2 2 2 0 TPR repeat PG_binding_1 PF01471.13 OAP64625.1 - 0.098 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain TPR_19 PF14559.1 OAP64625.1 - 0.2 11.9 1.6 14 6.0 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP64625.1 - 0.24 12.1 4.1 0.39 11.4 0.1 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAP64625.1 - 0.99 10.0 6.7 1.9 9.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat EthD PF07110.6 OAP64628.1 - 1.6e-08 35.3 0.2 5.8e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 EthD domain Lentiviral_Tat PF02998.9 OAP64628.1 - 0.00037 20.2 0.2 0.00062 19.5 0.1 1.3 1 0 0 1 1 1 1 Lentiviral Tat protein HSP70 PF00012.15 OAP64629.1 - 2.5e-273 907.4 4.4 2.9e-273 907.3 3.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAP64629.1 - 9e-17 60.6 0.0 1.3e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 OAP64629.1 - 0.003 17.2 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 OAP64629.1 - 0.0037 16.4 0.1 0.033 13.2 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 OAP64629.1 - 0.083 12.7 3.5 3.8 7.3 0.2 3.1 2 2 0 2 2 2 0 Cell division protein FtsA CHZ PF09649.5 OAP64630.1 - 3.4e-10 38.9 3.7 3.4e-10 38.9 2.6 2.9 4 0 0 4 4 4 1 Histone chaperone domain CHZ DTHCT PF08070.6 OAP64630.1 - 1.4 9.5 6.1 1.5 9.4 0.1 2.1 1 1 1 2 2 2 0 DTHCT (NUC029) region APG6 PF04111.7 OAP64630.1 - 5.8 5.8 10.5 6.1 5.7 7.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 VEFS-Box PF09733.4 OAP64631.1 - 0.00013 21.6 0.6 0.00025 20.7 0.4 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF445 PF04286.7 OAP64631.1 - 0.074 12.5 2.4 0.065 12.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF445) zf-C2H2_4 PF13894.1 OAP64631.1 - 0.18 12.1 1.9 0.4 11.1 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ssl1 PF04056.9 OAP64632.1 - 1.2e-51 175.1 0.0 1.5e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 OAP64632.1 - 1e-09 38.7 0.0 1.6e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 OAP64632.1 - 0.0059 16.3 0.0 0.008 15.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Peptidase_M1 PF01433.15 OAP64633.1 - 1.3e-130 436.0 0.1 2.3e-130 435.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 OAP64633.1 - 1.9e-69 234.4 0.0 3.3e-69 233.5 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Ras PF00071.17 OAP64633.1 - 3.1e-64 215.2 1.3 4.8e-64 214.6 0.3 1.8 2 0 0 2 2 2 1 Ras family Peptidase_MA_2 PF13485.1 OAP64633.1 - 3.1e-22 78.9 2.1 6.5e-22 77.9 1.1 1.9 2 0 0 2 2 1 1 Peptidase MA superfamily Miro PF08477.8 OAP64633.1 - 1.5e-20 73.8 0.4 3.9e-20 72.5 0.0 2.0 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 OAP64633.1 - 1.2e-15 57.1 0.1 5.5e-15 55.0 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAP64633.1 - 0.00032 19.8 0.1 0.00058 19.0 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAP64633.1 - 0.00057 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAP64633.1 - 0.0012 18.7 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2808 PF10989.3 OAP64633.1 - 0.0049 16.4 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) SRPRB PF09439.5 OAP64633.1 - 0.0063 15.7 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 OAP64633.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 OAP64633.1 - 0.041 14.0 0.1 2.1 8.5 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TFIIE_beta PF02186.10 OAP64633.1 - 0.073 13.0 0.0 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 TFIIE beta subunit core domain NUDIX PF00293.23 OAP64634.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain F-box PF00646.28 OAP64635.1 - 0.0061 16.1 0.2 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 OAP64635.1 - 0.012 15.5 0.1 0.14 12.1 0.0 2.5 3 0 0 3 3 3 0 PRANC domain DUF1996 PF09362.5 OAP64637.1 - 6.7e-75 251.7 0.4 9.5e-75 251.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FBA_2 PF07735.12 OAP64637.1 - 0.17 11.7 0.1 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 F-box associated Asparaginase PF00710.15 OAP64638.1 - 5.8e-99 330.8 0.0 2.2e-98 329.0 0.0 1.8 1 1 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 OAP64638.1 - 2.6e-11 43.7 0.3 5e-11 42.7 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP64638.1 - 3.2e-10 40.2 0.5 4.8e-07 30.1 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 OAP64638.1 - 3.4e-09 36.0 5.2 7.1e-05 22.4 0.3 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 OAP64638.1 - 1.1e-06 28.6 0.6 8e-06 25.9 0.3 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP64638.1 - 5.4e-05 23.0 2.3 0.063 13.5 0.1 4.0 4 0 0 4 4 4 1 Ankyrin repeat NmrA PF05368.8 OAP64639.1 - 2.2e-68 230.0 0.0 2.6e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP64639.1 - 0.00016 21.7 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF3227 PF11537.3 OAP64639.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) His_Phos_1 PF00300.17 OAP64640.1 - 1.8e-22 80.1 0.0 2.7e-22 79.5 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NUP PF06516.6 OAP64641.1 - 9.7e-127 422.1 0.1 1.2e-126 421.8 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) UPF0029 PF01205.14 OAP64642.1 - 1.6e-31 108.2 0.1 4.5e-31 106.7 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 OAP64642.1 - 7e-08 32.3 0.0 1.6e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 RWD domain P_C PF06640.6 OAP64642.1 - 0.37 10.7 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 P protein C-terminus MIP PF00230.15 OAP64643.1 - 1.2e-41 142.6 11.2 1.6e-41 142.2 7.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Cupin_2 PF07883.6 OAP64645.1 - 5e-09 35.5 0.0 8.5e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 OAP64645.1 - 0.014 14.7 0.1 0.027 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Clr5 PF14420.1 OAP64646.1 - 8.7e-19 67.1 0.8 1.8e-18 66.1 0.5 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 OAP64646.1 - 1.7e-12 47.0 3.0 2.7e-06 27.2 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAP64646.1 - 0.0011 19.5 1.3 0.022 15.4 0.5 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAP64646.1 - 0.0013 18.5 7.2 0.0021 17.9 0.0 4.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAP64646.1 - 0.0068 16.0 2.2 0.037 13.6 0.1 2.9 2 1 1 3 3 3 2 TPR repeat DUF3856 PF12968.2 OAP64646.1 - 0.0083 15.9 0.4 0.52 10.1 0.2 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_14 PF13428.1 OAP64646.1 - 0.041 14.5 2.2 7.2 7.5 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAP64646.1 - 0.06 13.6 0.1 0.75 10.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP64646.1 - 0.11 12.4 2.7 6.4 6.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAP64646.1 - 0.6 9.8 2.9 2.1 8.1 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1100 PF06500.6 OAP64647.1 - 4.4e-14 51.8 0.0 7.6e-14 51.0 0.0 1.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.2 OAP64647.1 - 4.6e-13 49.5 0.0 8.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP64647.1 - 1.5e-12 47.4 0.0 2.3e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAP64647.1 - 2.5e-09 36.9 0.0 4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 OAP64647.1 - 5.8e-05 22.4 0.0 0.00016 21.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 OAP64647.1 - 8.8e-05 22.0 0.0 0.00041 19.8 0.0 2.0 1 1 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 OAP64647.1 - 0.0005 19.8 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 OAP64647.1 - 0.0019 17.6 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 OAP64647.1 - 0.01 15.4 0.1 0.045 13.2 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_7 PF12715.2 OAP64647.1 - 0.011 14.7 0.1 0.075 11.9 0.0 2.0 2 0 0 2 2 2 0 Abhydrolase family DLH PF01738.13 OAP64647.1 - 0.017 14.4 0.0 0.048 12.9 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 OAP64647.1 - 0.032 13.8 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold USP8_dimer PF08969.6 OAP64647.1 - 0.1 12.5 0.2 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain Esterase_phd PF10503.4 OAP64647.1 - 0.19 10.9 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase F-box PF00646.28 OAP64648.1 - 5.5e-05 22.7 1.5 0.00016 21.2 1.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAP64648.1 - 0.00038 20.1 0.8 0.00091 18.9 0.6 1.6 1 0 0 1 1 1 1 F-box-like p450 PF00067.17 OAP64649.1 - 3.9e-51 174.0 0.0 1e-50 172.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 CN_hydrolase PF00795.17 OAP64650.1 - 1.9e-21 76.2 0.0 1e-20 73.8 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Asp_Glu_race PF01177.17 OAP64651.1 - 1.7e-30 106.5 0.4 2.5e-30 106.0 0.3 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Catalase PF00199.14 OAP64652.1 - 1.5e-69 234.5 0.0 2e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Catalase Ank_2 PF12796.2 OAP64654.1 - 1.6e-08 34.7 0.1 2.7e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP64654.1 - 0.0029 18.0 0.1 0.07 13.6 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF4611 PF15387.1 OAP64654.1 - 0.058 13.5 2.3 0.12 12.5 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Amidohydro_4 PF13147.1 OAP64655.1 - 2.1e-28 100.1 0.0 2.8e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 OAP64655.1 - 2.7e-15 56.8 1.5 3.6e-13 49.8 1.0 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 OAP64655.1 - 3.1e-14 52.5 2.7 6.5e-14 51.5 1.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP64655.1 - 5.8e-10 38.9 0.3 9.5e-06 25.0 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 OAP64655.1 - 0.042 13.9 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Transp_cyt_pur PF02133.10 OAP64656.1 - 1.2e-89 300.8 41.4 1.7e-89 300.4 28.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ADH_N PF08240.7 OAP64657.1 - 4.6e-26 90.6 4.0 4.6e-26 90.6 2.8 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP64657.1 - 2.3e-05 23.9 0.1 0.0027 17.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 OAP64657.1 - 0.00049 19.6 0.4 0.00049 19.6 0.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Neuroparsin PF07327.6 OAP64657.1 - 0.01 16.0 1.7 0.026 14.7 1.2 1.6 1 0 0 1 1 1 0 Neuroparsin ThiF PF00899.16 OAP64657.1 - 0.048 13.4 0.1 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family Exo_endo_phos PF03372.18 OAP64658.1 - 3.5e-21 76.2 0.1 6.6e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 OAP64658.1 - 3.1e-05 23.6 0.1 0.00039 20.1 0.1 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat WW PF00397.21 OAP64659.1 - 6.8e-08 32.2 3.5 1.6e-07 31.0 2.5 1.7 1 0 0 1 1 1 1 WW domain Aminotran_3 PF00202.16 OAP64660.1 - 1.2e-93 313.6 0.0 1.5e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.13 OAP64661.1 - 2.5e-08 33.1 0.0 2.4e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64661.1 - 5.7e-05 22.9 8.0 0.00013 21.7 5.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.19 OAP64662.1 - 1.1e-42 146.2 0.5 2.4e-42 145.1 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase DUF2012 PF09430.5 OAP64663.1 - 5.6e-28 97.2 0.0 7.3e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) EAV_GS PF01309.13 OAP64663.1 - 0.056 12.9 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein DUF1749 PF08538.5 OAP64665.1 - 1.1e-68 231.3 0.0 1.3e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 OAP64665.1 - 1.4e-10 41.4 0.7 2.3e-10 40.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP64665.1 - 7.4e-06 25.7 0.0 3e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 OAP64665.1 - 0.0011 18.5 0.1 0.0038 16.8 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Cutinase PF01083.17 OAP64665.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase MFS_1 PF07690.11 OAP64666.1 - 6.2e-42 143.5 44.3 6.2e-42 143.5 30.7 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP64666.1 - 3.8e-05 22.4 17.4 3.8e-05 22.4 12.1 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2358 PF10184.4 OAP64667.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) TrkH PF02386.11 OAP64668.1 - 1.2e-122 408.9 12.7 2.3e-120 401.4 3.8 2.1 2 0 0 2 2 2 2 Cation transport protein Glyco_hydro_76 PF03663.9 OAP64669.1 - 5.5e-142 473.5 22.9 7.2e-142 473.1 15.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 OAP64669.1 - 0.002 16.4 0.8 0.5 8.5 0.0 3.1 3 1 1 4 4 4 2 Putative glycosyl hydrolase of unknown function (DUF1680) DUF4048 PF13257.1 OAP64670.1 - 2.3e-39 135.5 11.9 8e-37 127.2 8.3 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4048) Pkinase PF00069.20 OAP64671.1 - 1.1e-66 224.6 0.0 2e-66 223.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP64671.1 - 1.1e-45 155.7 0.0 2.1e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP64671.1 - 0.00097 18.1 0.0 0.0022 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like MFS_1 PF07690.11 OAP64672.1 - 3.8e-27 94.9 22.6 3.8e-27 94.9 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 OAP64673.1 - 4e-59 200.1 0.9 4.5e-59 199.9 0.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 OAP64674.1 - 2.7e-49 167.9 0.0 3.3e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 OAP64674.1 - 6.7e-06 25.9 0.7 1.9e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 ThiF family NAD_binding_8 PF13450.1 OAP64674.1 - 0.00032 20.6 0.0 0.0012 18.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 OAP64674.1 - 0.00056 18.8 0.0 0.22 10.3 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 OAP64674.1 - 0.00075 18.4 0.0 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 OAP64674.1 - 0.00091 19.4 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 OAP64674.1 - 0.0013 18.6 0.0 0.018 14.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 OAP64674.1 - 0.0015 18.2 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 OAP64674.1 - 0.0018 18.6 0.0 0.025 14.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP64674.1 - 0.0035 17.1 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 OAP64674.1 - 0.0095 15.0 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 OAP64674.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 OAP64674.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 OAP64674.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TadE PF07811.7 OAP64674.1 - 0.63 9.9 5.0 0.25 11.2 0.2 2.3 2 0 0 2 2 2 0 TadE-like protein TRI12 PF06609.8 OAP64675.1 - 1.5e-32 112.6 30.6 1.8e-32 112.3 21.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP64675.1 - 2.9e-17 62.4 62.3 1.1e-16 60.5 37.8 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP64675.1 - 1.3e-09 37.1 17.4 1.3e-09 37.1 12.1 3.2 3 1 1 4 4 4 1 Sugar (and other) transporter ADH_N PF08240.7 OAP64677.1 - 4.4e-28 97.2 0.2 8.4e-28 96.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP64677.1 - 4.7e-21 74.7 0.0 8.5e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DZR PF12773.2 OAP64677.1 - 0.15 11.9 0.4 0.32 10.8 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon DNA_ligase_A_M PF01068.16 OAP64678.1 - 5.2e-24 84.7 0.0 1.3e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAP64678.1 - 2.5e-10 40.4 0.0 5.5e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 DNA ligase N terminus AA_permease PF00324.16 OAP64679.1 - 1.1e-119 399.9 33.6 1.3e-119 399.6 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAP64679.1 - 6e-37 127.1 37.3 7.1e-37 126.9 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease Scramblase PF03803.10 OAP64680.1 - 7.4e-51 172.3 0.0 1.4e-26 92.9 0.0 2.9 1 1 1 2 2 2 2 Scramblase Kelch_5 PF13854.1 OAP64681.1 - 1.5e-10 40.8 7.1 8.5e-08 31.9 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 OAP64681.1 - 1.2e-06 28.4 10.0 0.0041 17.2 0.1 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 OAP64681.1 - 4.5e-06 26.3 8.8 0.51 10.1 0.2 5.5 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 OAP64681.1 - 0.00098 19.2 5.4 2.9 8.2 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 OAP64681.1 - 0.015 14.8 4.4 1.6 8.3 0.0 4.6 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 OAP64681.1 - 0.045 13.5 1.7 1.9 8.4 0.0 3.7 4 0 0 4 4 4 0 Kelch motif p450 PF00067.17 OAP64682.1 - 1.1e-42 146.2 0.1 4.2e-28 98.1 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.13 OAP64683.1 - 9.8e-12 44.2 0.1 1.6e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UPF0075 PF03702.9 OAP64684.1 - 7.6e-84 281.6 0.0 8.9e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) adh_short PF00106.20 OAP64685.1 - 1.4e-26 93.4 2.4 2.2e-26 92.7 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64685.1 - 1.9e-25 90.0 0.2 2.2e-25 89.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64685.1 - 2.1e-12 47.0 0.8 5e-12 45.8 0.5 1.7 1 1 0 1 1 1 1 KR domain ACT PF01842.20 OAP64685.1 - 0.12 11.8 0.2 5.8 6.5 0.1 2.6 3 0 0 3 3 3 0 ACT domain Sugar_tr PF00083.19 OAP64686.1 - 4.2e-74 249.7 24.7 4.8e-74 249.5 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64686.1 - 3.5e-25 88.4 41.5 8.3e-18 64.2 9.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.1 OAP64686.1 - 0.17 11.5 5.8 0.051 13.2 1.2 2.2 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 OAP64686.1 - 0.17 11.4 5.4 0.57 9.7 3.7 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 OAP64686.1 - 0.41 10.3 8.3 0.035 13.7 1.7 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 OAP64686.1 - 1.1 8.8 3.5 3.1 7.4 2.5 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Transgly_assoc PF04226.8 OAP64686.1 - 3 8.0 11.6 0.086 12.9 2.3 2.9 3 0 0 3 3 3 0 Transglycosylase associated protein GFO_IDH_MocA PF01408.17 OAP64687.1 - 1.7e-13 51.1 0.0 2.8e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Anillin PF08174.6 OAP64687.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Cell division protein anillin TPR_12 PF13424.1 OAP64688.1 - 2.7e-40 136.1 5.4 1.5e-11 44.0 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 OAP64688.1 - 1.3e-25 88.5 0.1 5.4e-06 26.1 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat HET PF06985.6 OAP64688.1 - 6.1e-18 65.3 0.3 1.4e-17 64.1 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.23 OAP64688.1 - 1.1e-17 62.7 9.6 0.0083 15.7 0.4 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 OAP64688.1 - 4.9e-15 54.9 8.1 0.0028 17.2 0.1 6.1 4 2 3 7 7 7 5 TPR repeat TPR_7 PF13176.1 OAP64688.1 - 1.2e-11 43.4 1.5 0.17 11.7 0.0 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAP64688.1 - 1.2e-10 40.4 14.0 0.19 11.7 0.2 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAP64688.1 - 7e-09 34.8 10.3 0.31 10.9 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAP64688.1 - 7.6e-08 32.8 0.0 1.5 9.5 0.0 5.9 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP64688.1 - 2.4e-06 27.6 0.1 6.5 7.6 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAP64688.1 - 6.3e-05 23.2 2.8 0.019 15.2 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 OAP64688.1 - 0.00026 20.5 3.5 0.23 10.8 0.1 3.3 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 OAP64688.1 - 0.0017 18.6 4.2 7.2 7.3 0.1 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat NB-ARC PF00931.17 OAP64688.1 - 0.0048 15.7 0.0 0.0082 15.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 OAP64688.1 - 0.029 14.5 0.4 63 4.1 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Bac_DnaA_C PF08299.6 OAP64688.1 - 0.067 13.0 0.0 7.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix PPR PF01535.15 OAP64688.1 - 0.22 11.5 1.8 19 5.5 0.0 4.5 5 0 0 5 5 5 0 PPR repeat ABC_tran PF00005.22 OAP64689.1 - 8.5e-50 168.6 0.0 4.6e-26 91.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 OAP64689.1 - 7.6e-26 90.9 52.0 2.4e-18 66.2 18.7 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 OAP64689.1 - 6.1e-22 78.9 0.1 0.00019 21.4 0.0 4.7 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 OAP64689.1 - 7.1e-11 41.4 0.8 1.4e-05 24.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 OAP64689.1 - 9.2e-10 38.1 0.7 7.9e-06 25.2 0.1 3.8 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAP64689.1 - 9.5e-09 35.8 0.8 0.00077 19.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAP64689.1 - 1.1e-05 25.5 0.4 0.1 12.6 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 OAP64689.1 - 0.00023 20.3 0.1 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF4162 PF13732.1 OAP64689.1 - 0.00036 20.9 0.1 0.0031 17.9 0.0 2.6 3 0 0 3 3 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.1 OAP64689.1 - 0.0008 18.5 0.0 0.19 10.7 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 OAP64689.1 - 0.0025 17.2 0.0 0.65 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP64689.1 - 0.0026 17.9 0.0 0.57 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 OAP64689.1 - 0.0058 16.6 0.1 0.38 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAP64689.1 - 0.0064 16.2 2.2 0.97 9.2 0.2 3.0 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 OAP64689.1 - 0.0066 15.5 0.0 2.2 7.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 OAP64689.1 - 0.0066 16.0 0.2 2.2 7.8 0.0 2.9 3 1 0 3 3 2 1 AAA domain MutS_V PF00488.16 OAP64689.1 - 0.01 15.2 0.3 2.7 7.3 0.0 2.6 3 0 0 3 3 3 0 MutS domain V AAA_10 PF12846.2 OAP64689.1 - 0.017 14.5 0.1 2.6 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 OAP64689.1 - 0.019 14.8 0.0 2.8 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 OAP64689.1 - 0.031 13.6 0.7 7.2 5.9 0.2 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 OAP64689.1 - 0.037 14.2 0.0 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 OAP64689.1 - 0.063 12.7 0.1 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 OAP64689.1 - 0.1 11.3 0.9 2.4 6.8 0.1 2.4 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 OAP64689.1 - 0.1 13.0 0.0 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 OAP64689.1 - 0.14 12.0 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 OAP64689.1 - 0.16 10.3 0.1 2.3 6.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 OAP64689.1 - 0.34 10.8 8.9 0.84 9.6 0.0 4.4 4 2 0 4 4 3 0 Putative exonuclease SbcCD, C subunit ABC2_membrane PF01061.19 OAP64690.1 - 1.4e-82 275.9 64.9 6.1e-44 149.6 11.9 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 OAP64690.1 - 4.3e-34 117.7 0.0 1.2e-16 61.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 OAP64690.1 - 3.2e-27 94.1 0.1 9.7e-24 83.0 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 OAP64690.1 - 5.9e-09 35.9 0.1 2e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 OAP64690.1 - 1.3e-08 34.2 32.8 1.7e-08 33.9 7.9 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_17 PF13207.1 OAP64690.1 - 4.4e-06 27.5 0.2 0.13 13.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 OAP64690.1 - 1.4e-05 25.2 0.1 0.077 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP64690.1 - 0.00011 21.7 0.3 0.0048 16.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 OAP64690.1 - 0.00011 22.3 0.0 0.24 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAP64690.1 - 0.00013 21.4 3.3 0.006 16.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 OAP64690.1 - 0.00035 20.6 0.5 0.11 12.4 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 OAP64690.1 - 0.00037 19.9 0.7 0.013 14.9 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 OAP64690.1 - 0.00085 18.5 0.1 0.003 16.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 OAP64690.1 - 0.0012 18.7 5.7 0.048 13.5 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 OAP64690.1 - 0.0013 18.4 1.0 0.75 9.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain SMC_N PF02463.14 OAP64690.1 - 0.0027 16.9 0.0 0.29 10.3 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 OAP64690.1 - 0.0028 17.2 1.1 0.7 9.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 OAP64690.1 - 0.003 17.5 1.6 0.084 12.8 0.1 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 OAP64690.1 - 0.014 15.0 0.6 3.5 7.2 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 OAP64690.1 - 0.033 14.5 9.7 0.3 11.3 0.0 3.7 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.4 OAP64690.1 - 0.052 13.0 0.5 2.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 OAP64690.1 - 0.077 12.5 0.2 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 OAP64690.1 - 0.098 12.9 3.9 0.49 10.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 OAP64690.1 - 0.12 12.8 0.5 7.6 7.0 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein FtsK_SpoIIIE PF01580.13 OAP64690.1 - 0.14 11.6 1.9 1.8 8.0 0.0 2.5 2 1 0 2 2 2 0 FtsK/SpoIIIE family BTB PF00651.26 OAP64691.1 - 1.7e-06 28.0 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DsrC PF04358.8 OAP64691.1 - 0.029 14.6 0.4 0.28 11.4 0.1 2.2 1 1 1 2 2 2 0 DsrC like protein Daxx PF03344.10 OAP64691.1 - 2.7 6.3 27.1 5 5.4 18.8 1.4 1 0 0 1 1 1 0 Daxx Family PI3K_1B_p101 PF10486.4 OAP64691.1 - 9 3.7 10.3 5.2 4.5 5.9 1.4 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UCH PF00443.24 OAP64692.1 - 1.1e-48 165.7 0.0 2.8e-48 164.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAP64692.1 - 2.4e-20 73.1 0.0 2.1e-19 70.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_2 PF13923.1 OAP64693.1 - 4.3e-08 33.0 9.2 7.3e-08 32.3 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP64693.1 - 3.2e-07 29.9 7.4 6.4e-07 28.9 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP64693.1 - 5.2e-07 29.2 5.8 9.5e-07 28.3 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP64693.1 - 8.2e-07 28.7 7.6 1.5e-06 27.9 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAP64693.1 - 1.1e-05 25.0 4.6 2.1e-05 24.1 3.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAP64693.1 - 1.3e-05 24.9 6.6 7.3e-05 22.5 4.7 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 OAP64693.1 - 0.067 12.7 6.4 0.16 11.4 4.4 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 OAP64693.1 - 0.071 12.8 6.5 0.099 12.3 3.1 2.3 1 1 1 2 2 2 0 RING-type zinc-finger DUF4066 PF13278.1 OAP64694.1 - 1.2e-23 83.2 0.8 3e-19 68.9 0.4 2.8 2 1 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 OAP64694.1 - 5e-05 22.7 0.7 0.0002 20.8 0.4 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family adh_short PF00106.20 OAP64695.1 - 2.5e-07 30.7 0.1 3.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 OAP64695.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 OAP64695.1 - 0.015 14.9 0.1 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAP64695.1 - 0.018 15.0 0.3 0.028 14.4 0.2 1.8 1 1 0 1 1 1 0 NADH(P)-binding Frataxin_Cyay PF01491.11 OAP64698.1 - 1.6e-32 111.5 0.0 2.2e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Methyltransf_2 PF00891.13 OAP64699.1 - 1.7e-32 112.5 0.0 2.5e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 OAP64699.1 - 0.00034 20.3 0.0 0.0039 16.9 0.0 2.5 2 0 0 2 2 2 1 Dimerisation domain NinB PF05772.7 OAP64699.1 - 0.0096 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 NinB protein Fungal_trans PF04082.13 OAP64700.1 - 1.6e-08 33.7 0.2 2.7e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64701.1 - 4e-05 23.4 9.0 6.4e-05 22.7 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.4 OAP64701.1 - 0.35 10.2 13.8 0.51 9.7 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.6 OAP64701.1 - 8.4 4.3 6.0 10 4.1 4.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Dickkopf_N PF04706.7 OAP64701.1 - 9.9 6.4 13.5 12 6.1 1.8 2.5 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region UNC-93 PF05978.11 OAP64702.1 - 6.1e-09 35.5 5.3 6.1e-09 35.5 3.7 2.5 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 OAP64702.1 - 6.1e-09 35.0 38.3 7e-05 21.7 19.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M20 PF01546.23 OAP64703.1 - 7.6e-24 84.2 0.1 1e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAP64703.1 - 6.7e-06 25.8 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 OAP64703.1 - 0.011 15.5 0.1 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 DUF2365 PF10157.4 OAP64703.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Methyltransf_11 PF08241.7 OAP64704.1 - 1e-17 64.3 0.1 1.8e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP64704.1 - 7.1e-15 54.8 0.0 1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP64704.1 - 5.4e-14 52.7 0.3 1.2e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP64704.1 - 5.8e-14 52.2 0.0 1.1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP64704.1 - 2.2e-10 40.8 0.0 4.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP64704.1 - 3e-08 33.2 0.0 3.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 OAP64704.1 - 8e-08 32.1 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP64704.1 - 9.6e-08 31.4 0.0 1.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 OAP64704.1 - 1.6e-07 31.3 2.0 2.9e-07 30.4 0.3 2.2 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 OAP64704.1 - 3.8e-06 26.4 0.2 5.4e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.4 OAP64704.1 - 0.00072 19.0 0.1 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 OAP64704.1 - 0.00082 18.5 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 OAP64704.1 - 0.0023 17.5 0.0 0.003 17.2 0.0 1.3 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 OAP64704.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 OAP64704.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ABC_membrane PF00664.18 OAP64705.1 - 1.4e-85 287.0 38.6 6.9e-45 153.5 11.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAP64705.1 - 1.8e-67 225.8 0.1 2.3e-33 115.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAP64705.1 - 1.9e-14 53.4 0.0 1.8e-05 24.1 0.0 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP64705.1 - 5.4e-12 46.2 0.0 0.0002 21.4 0.0 4.2 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 OAP64705.1 - 9.6e-09 35.4 8.1 2.5e-06 27.6 0.1 3.2 3 1 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 OAP64705.1 - 1.2e-08 34.3 0.1 0.0038 16.4 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAP64705.1 - 2e-07 31.8 0.0 0.0043 17.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAP64705.1 - 2.1e-07 30.3 2.8 0.0083 15.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAP64705.1 - 3e-06 26.7 0.1 0.069 12.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 OAP64705.1 - 4e-06 25.6 5.3 0.013 14.1 0.1 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_30 PF13604.1 OAP64705.1 - 6.1e-06 25.9 2.7 0.033 13.7 0.1 4.0 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 OAP64705.1 - 9.2e-05 22.5 4.7 0.15 12.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAP64705.1 - 0.00068 19.9 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 OAP64705.1 - 0.0016 18.3 2.0 0.64 9.9 0.2 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 OAP64705.1 - 0.0021 17.9 0.1 2.3 8.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAP64705.1 - 0.0027 17.4 3.2 1.3 8.8 0.0 3.4 3 0 0 3 3 3 2 Part of AAA domain PRK PF00485.13 OAP64705.1 - 0.0033 17.0 1.4 1.1 8.7 0.0 2.9 4 0 0 4 4 2 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 OAP64705.1 - 0.0057 16.3 0.5 4 7.1 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 OAP64705.1 - 0.0057 16.4 1.1 1.1 9.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_28 PF13521.1 OAP64705.1 - 0.0069 16.3 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAP64705.1 - 0.0072 15.8 2.7 1.2 8.5 0.1 3.4 4 0 0 4 4 4 1 AAA-like domain Tnp_DNA_bind PF14706.1 OAP64705.1 - 0.008 15.8 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Transposase DNA-binding AAA_5 PF07728.9 OAP64705.1 - 0.012 15.3 0.1 8.9 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 OAP64705.1 - 0.017 15.0 0.0 6.3 6.7 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 OAP64705.1 - 0.018 15.4 2.3 1.5 9.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 OAP64705.1 - 0.018 14.1 0.2 0.79 8.7 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 OAP64705.1 - 0.02 15.4 0.3 9.5 6.7 0.1 2.7 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 OAP64705.1 - 0.022 14.8 0.2 11 6.2 0.0 3.0 3 0 0 3 3 2 0 RNA helicase NACHT PF05729.7 OAP64705.1 - 0.027 14.1 1.1 3.3 7.3 0.2 3.2 3 0 0 3 3 3 0 NACHT domain AAA_15 PF13175.1 OAP64705.1 - 0.043 12.8 0.0 1.9 7.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain NB-ARC PF00931.17 OAP64705.1 - 0.071 11.9 0.3 6.5 5.5 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.12 OAP64705.1 - 0.27 10.7 1.4 13 5.2 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 OAP64705.1 - 1.1 9.0 5.9 27 4.5 0.4 3.8 3 0 0 3 3 3 0 Dynamin family Zn_clus PF00172.13 OAP64706.1 - 8.4e-09 35.2 9.8 1.6e-08 34.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP64706.1 - 0.00047 18.8 0.8 0.00069 18.3 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain D-aminoacyl_C PF07908.7 OAP64706.1 - 0.087 12.1 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region TauD PF02668.11 OAP64707.1 - 1e-19 71.2 3.5 1.8e-17 63.9 2.4 2.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 OAP64709.1 - 3.7e-29 101.5 14.6 3.7e-29 101.5 10.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 OAP64709.1 - 0.65 10.0 5.6 0.54 10.3 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF2975 PF11188.3 OAP64710.1 - 0.11 12.2 5.9 0.098 12.3 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) Aa_trans PF01490.13 OAP64711.1 - 2.6e-42 144.7 34.2 3e-42 144.5 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 OAP64711.1 - 0.0005 18.9 17.1 0.0005 18.9 11.8 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Sec6 PF06046.8 OAP64712.1 - 6.4e-145 483.4 2.4 1.1e-144 482.5 1.6 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 OAP64712.1 - 0.00096 18.0 1.4 0.021 13.6 0.1 2.6 2 0 0 2 2 2 1 Vps53-like, N-terminal LOH1CR12 PF10158.4 OAP64712.1 - 0.021 14.5 0.5 0.17 11.6 0.1 2.5 2 0 0 2 2 2 0 Tumour suppressor protein MutS_III PF05192.13 OAP64712.1 - 0.037 13.8 0.3 0.97 9.1 0.2 2.7 1 1 0 1 1 1 0 MutS domain III MukB PF04310.7 OAP64712.1 - 0.091 12.0 0.4 13 5.0 0.0 2.7 3 0 0 3 3 3 0 MukB N-terminal CsbD PF05532.7 OAP64712.1 - 0.54 9.9 2.7 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 CsbD-like zf-ZPR1 PF03367.8 OAP64712.1 - 2.7 7.1 4.9 2 7.5 0.1 2.9 3 0 0 3 3 3 0 ZPR1 zinc-finger domain Ribosomal_L4 PF00573.17 OAP64713.1 - 2e-38 131.7 0.3 2.7e-38 131.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 OAP64713.1 - 3.2e-28 97.4 1.5 4.8e-28 96.8 0.1 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Fungal_trans PF04082.13 OAP64715.1 - 2.9e-16 59.1 0.1 4.6e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BCS1_N PF08740.6 OAP64716.1 - 3.1e-30 105.2 0.2 3.1e-30 105.2 0.2 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 OAP64716.1 - 1.3e-16 61.0 0.0 1.7e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAP64716.1 - 0.0047 17.7 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAP64716.1 - 0.0052 16.2 0.0 0.086 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAP64716.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 OAP64716.1 - 0.047 13.4 0.0 0.15 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 OAP64716.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 OAP64716.1 - 0.14 12.1 1.0 0.79 9.6 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AMP-binding PF00501.23 OAP64718.1 - 4.2e-44 150.5 0.0 5.9e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme IMS PF00817.15 OAP64718.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 impB/mucB/samB family SEP PF08059.8 OAP64720.1 - 1.8e-28 98.6 0.2 3.4e-28 97.7 0.2 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 OAP64720.1 - 6e-08 32.6 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 OAP64720.1 - 4.1e-06 26.2 5.2 1.9e-05 24.0 3.6 2.0 1 1 0 1 1 1 1 UBA-like domain Spt20 PF12090.3 OAP64720.1 - 0.069 12.4 0.2 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Spt20 family 60KD_IMP PF02096.15 OAP64721.1 - 5.9e-33 114.1 2.6 5.9e-33 114.1 1.8 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein DUF106 PF01956.11 OAP64721.1 - 1 8.8 0.0 1 8.8 0.0 3.2 4 0 0 4 4 4 0 Integral membrane protein DUF106 TPP_enzyme_N PF02776.13 OAP64722.1 - 6.4e-46 155.9 0.0 1.4e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAP64722.1 - 7.4e-24 84.0 0.1 4.2e-23 81.5 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAP64722.1 - 5.1e-21 74.8 0.0 8.8e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain GST_N_3 PF13417.1 OAP64723.1 - 7.1e-08 32.5 0.0 1.5e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP64723.1 - 6.2e-05 22.8 0.2 0.00013 21.7 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short PF00106.20 OAP64724.1 - 5.5e-23 81.7 1.5 6.6e-22 78.1 1.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64724.1 - 1.2e-19 71.0 0.0 1.4e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64724.1 - 2.1e-11 43.8 0.0 4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Ceramidase PF05875.7 OAP64725.1 - 9.6e-57 192.0 11.8 1.3e-56 191.7 8.2 1.1 1 0 0 1 1 1 1 Ceramidase HPP PF04982.8 OAP64725.1 - 0.011 15.6 0.6 0.03 14.1 0.4 1.7 1 0 0 1 1 1 0 HPP family Leader_Trp PF08255.6 OAP64725.1 - 0.033 13.8 1.5 0.12 12.1 1.0 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide DUF4212 PF13937.1 OAP64725.1 - 0.073 13.0 10.0 0.21 11.6 0.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4212) p450 PF00067.17 OAP64726.1 - 4.3e-56 190.3 0.0 5.8e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 OAP64727.1 - 2.2e-21 76.2 0.0 5.5e-21 74.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP64727.1 - 1e-07 32.4 0.0 2e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP64727.1 - 2.2e-06 28.0 0.0 5.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP64727.1 - 0.00067 20.0 0.0 0.0071 16.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP64727.1 - 0.0036 16.8 0.0 0.052 13.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 OAP64727.1 - 0.0037 16.8 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 OAP64727.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 OAP64727.1 - 0.017 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 OAP64727.1 - 0.019 15.3 0.0 0.078 13.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 OAP64727.1 - 0.026 13.9 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 OAP64727.1 - 0.035 13.2 0.0 1 8.4 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 OAP64727.1 - 0.037 14.0 0.0 0.54 10.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 OAP64727.1 - 0.037 14.0 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 OAP64727.1 - 0.071 12.1 0.0 0.3 10.1 0.0 1.9 2 1 0 2 2 2 0 Putative methyltransferase NmrA PF05368.8 OAP64728.1 - 9.2e-10 38.1 0.0 2.6e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 OAP64728.1 - 0.00057 19.8 0.2 0.0015 18.4 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP64728.1 - 0.0019 17.9 0.3 0.0031 17.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 OAP64728.1 - 0.003 16.5 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TMEM154 PF15102.1 OAP64729.1 - 0.017 14.8 4.1 0.049 13.3 0.0 2.3 1 1 0 2 2 2 0 TMEM154 protein family DUF4328 PF14219.1 OAP64729.1 - 0.12 11.6 0.2 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) CD34_antigen PF06365.7 OAP64729.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family ERG4_ERG24 PF01222.12 OAP64730.1 - 4.2e-145 483.5 20.6 4.9e-145 483.3 14.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family AA_permease_2 PF13520.1 OAP64732.1 - 1.8e-51 175.0 57.3 2.5e-51 174.5 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP64732.1 - 1.9e-20 72.6 45.6 2.6e-20 72.2 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease NAP PF00956.13 OAP64733.1 - 2e-35 122.0 0.4 2e-35 122.0 0.3 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) YL1 PF05764.8 OAP64733.1 - 6.6 6.2 18.5 12 5.3 12.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Syntaxin-6_N PF09177.6 OAP64734.1 - 8.4e-26 90.2 0.1 1.7e-25 89.2 0.1 1.5 1 0 0 1 1 1 1 Syntaxin 6, N-terminal SNARE PF05739.14 OAP64734.1 - 7e-13 48.0 0.7 7e-13 48.0 0.5 2.7 4 0 0 4 4 4 1 SNARE domain NPV_P10 PF05531.7 OAP64734.1 - 0.021 15.0 0.5 15 5.9 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Rifin_STEVOR PF02009.11 OAP64734.1 - 0.18 11.3 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family Snapin_Pallidin PF14712.1 OAP64734.1 - 0.3 11.4 1.7 1.7 9.0 0.1 2.4 2 1 0 2 2 2 0 Snapin/Pallidin IFT57 PF10498.4 OAP64734.1 - 0.66 8.6 2.4 6.6 5.3 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 HalX PF08663.5 OAP64734.1 - 2.6 8.0 6.3 0.36 10.8 0.6 2.4 2 1 0 2 2 2 0 HalX domain AMP-binding PF00501.23 OAP64736.1 - 7.7e-18 64.0 0.1 1.1e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Oest_recep PF02159.10 OAP64736.1 - 0.033 14.3 1.3 1.7 8.7 0.8 2.3 2 0 0 2 2 2 0 Oestrogen receptor FAD_binding_3 PF01494.14 OAP64737.1 - 5.2e-27 94.8 0.1 2e-26 92.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP64737.1 - 3.9e-14 52.3 0.5 1.9e-07 30.3 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 OAP64737.1 - 5.6e-08 32.2 0.3 0.0061 15.6 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAP64737.1 - 2.1e-07 30.8 0.1 4.7e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP64737.1 - 4.1e-07 29.2 0.7 4.1e-07 29.2 0.5 2.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP64737.1 - 1.3e-06 28.3 0.3 7.2e-06 26.0 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP64737.1 - 1.6e-06 28.4 0.3 7.1e-05 23.1 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAP64737.1 - 3.5e-06 25.9 0.2 0.0077 14.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 OAP64737.1 - 3.5e-05 22.8 0.4 0.14 11.0 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 OAP64737.1 - 4.9e-05 22.5 0.0 9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAP64737.1 - 5.1e-05 23.4 0.1 0.00017 21.7 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP64737.1 - 0.00014 20.8 0.1 0.0013 17.6 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 OAP64737.1 - 0.00036 19.1 0.4 0.0027 16.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.5 OAP64737.1 - 0.00046 19.1 0.0 0.0025 16.7 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.12 OAP64737.1 - 0.0011 18.1 0.1 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 OAP64737.1 - 0.0023 17.7 2.6 0.68 9.7 0.1 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 OAP64737.1 - 0.012 15.2 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 OAP64737.1 - 0.027 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.1 OAP64737.1 - 0.12 11.2 0.0 5.7 5.7 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 OAP64737.1 - 0.22 11.1 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HET PF06985.6 OAP64738.1 - 9e-13 48.5 1.5 1.7e-12 47.6 1.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Podoplanin PF05808.6 OAP64739.1 - 0.00032 20.2 1.9 0.00055 19.5 1.3 1.3 1 0 0 1 1 1 1 Podoplanin DUF1517 PF07466.6 OAP64739.1 - 0.058 12.3 0.5 0.11 11.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Rax2 PF12768.2 OAP64739.1 - 0.12 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.5 OAP64739.1 - 0.15 11.4 0.7 0.34 10.2 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NMO PF03060.10 OAP64740.1 - 2.8e-61 207.4 0.1 3.6e-61 207.1 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAP64740.1 - 2.1e-11 43.3 0.0 0.00011 21.1 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAP64740.1 - 0.0097 14.7 0.9 0.019 13.8 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 OAP64740.1 - 0.1 11.5 1.3 0.27 10.1 0.9 1.8 1 1 0 1 1 1 0 Conserved region in glutamate synthase RTA1 PF04479.8 OAP64741.1 - 4.9e-40 137.4 0.9 6.5e-40 137.0 0.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Ferric_reduct PF01794.14 OAP64741.1 - 0.0054 16.8 1.7 2.7 8.1 0.6 2.9 1 1 1 2 2 2 2 Ferric reductase like transmembrane component KdpC PF02669.10 OAP64741.1 - 0.026 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Hid1 PF12722.2 OAP64742.1 - 1.5e-253 843.5 0.0 7.2e-240 798.2 0.0 2.1 2 0 0 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 OAP64742.1 - 2e-79 267.4 0.0 4.2e-79 266.4 0.0 1.4 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 OAP64743.1 - 2.7e-17 62.9 0.0 2.1e-16 60.0 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore complex component DUF1501 PF07394.7 OAP64743.1 - 0.063 12.1 0.2 0.091 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) HpcH_HpaI PF03328.9 OAP64744.1 - 9.4e-40 135.8 0.0 1.1e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Cyt-b5 PF00173.23 OAP64745.1 - 6.7e-12 45.0 0.0 2.3e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.13 OAP64745.1 - 6.8e-11 41.2 0.0 2.5e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.16 OAP64745.1 - 5.5e-10 39.7 0.0 1.7e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 OAP64745.1 - 1.7e-08 34.1 0.0 5.1e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Glyco_hydro_18 PF00704.23 OAP64746.1 - 1e-11 44.9 0.0 1.9e-11 44.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PhoD PF09423.5 OAP64747.1 - 4.2e-58 196.9 0.0 7.2e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase bZIP_1 PF00170.16 OAP64748.1 - 5.5e-09 35.8 13.4 8.5e-07 28.8 6.2 2.3 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 OAP64748.1 - 1.1e-07 31.4 7.0 2.9e-07 30.0 4.9 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 OAP64748.1 - 0.00071 19.3 7.8 0.00071 19.3 5.4 2.0 2 0 0 2 2 2 1 Basic region leucine zipper DUF2408 PF10303.4 OAP64748.1 - 0.0054 16.8 0.1 0.009 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) SART-1 PF03343.8 OAP64748.1 - 0.0098 14.2 1.0 0.014 13.8 0.7 1.1 1 0 0 1 1 1 1 SART-1 family Fmp27_WPPW PF10359.4 OAP64748.1 - 0.014 13.8 1.3 0.018 13.4 0.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 OAP64748.1 - 0.042 13.4 2.1 0.072 12.6 1.5 1.3 1 0 0 1 1 1 0 IncA protein HAUS-augmin3 PF14932.1 OAP64748.1 - 0.088 11.9 1.9 0.15 11.2 1.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Mnd1 PF03962.10 OAP64748.1 - 0.11 12.1 4.4 0.19 11.3 3.1 1.3 1 0 0 1 1 1 0 Mnd1 family MFS_1 PF07690.11 OAP64749.1 - 3.5e-27 95.0 43.8 3.5e-27 95.0 30.4 3.6 2 2 2 4 4 4 3 Major Facilitator Superfamily Mito_carr PF00153.22 OAP64749.1 - 1.5e-12 47.0 0.3 0.0078 15.8 0.1 5.6 4 1 0 4 4 4 4 Mitochondrial carrier protein Glyco_hydro_71 PF03659.9 OAP64750.1 - 1.3e-138 461.7 6.9 1.3e-138 461.7 4.8 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 71 Fer2 PF00111.22 OAP64751.1 - 2e-14 53.0 1.3 2.9e-14 52.5 0.9 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.7 OAP64752.1 - 2.6e-36 124.5 13.2 2.6e-36 124.5 9.1 1.9 2 1 0 2 2 2 1 Rrp15p CAF1A PF12253.3 OAP64752.1 - 8.9 6.5 14.5 0.54 10.4 1.0 2.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A SRP54 PF00448.17 OAP64753.1 - 7.8e-72 240.8 2.4 2.1e-71 239.4 1.7 1.8 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 OAP64753.1 - 6.1e-26 90.7 3.2 6.1e-26 90.7 2.2 4.1 2 1 3 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 OAP64753.1 - 9.7e-13 48.0 0.0 3.5e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.14 OAP64753.1 - 2.8e-06 26.8 0.1 7.1e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 OAP64753.1 - 3.3e-06 27.0 0.0 8.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 OAP64753.1 - 2.9e-05 23.7 0.1 8.8e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 OAP64753.1 - 4.8e-05 22.8 0.3 0.00015 21.2 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 OAP64753.1 - 0.00015 22.6 0.0 0.00037 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAP64753.1 - 0.00015 20.8 0.0 0.00029 19.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin 6PF2K PF01591.13 OAP64753.1 - 0.00039 19.5 0.0 0.00075 18.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_31 PF13614.1 OAP64753.1 - 0.00098 19.0 0.0 0.25 11.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.15 OAP64753.1 - 0.0014 18.3 0.0 0.0041 16.7 0.0 1.8 1 0 0 1 1 1 1 Adenylylsulphate kinase TPP_enzyme_N PF02776.13 OAP64753.1 - 0.0026 17.2 0.5 0.067 12.6 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain AAA_19 PF13245.1 OAP64753.1 - 0.0032 17.1 0.2 0.025 14.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain SRPRB PF09439.5 OAP64753.1 - 0.0077 15.4 0.8 4.7 6.3 0.1 3.3 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 OAP64753.1 - 0.0098 15.3 0.1 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 OAP64753.1 - 0.01 15.8 0.0 0.032 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.12 OAP64753.1 - 0.019 14.3 0.1 0.049 12.9 0.0 1.7 1 0 0 1 1 1 0 Thymidylate kinase AAA_22 PF13401.1 OAP64753.1 - 0.022 14.8 0.1 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 OAP64753.1 - 0.042 12.4 0.5 0.077 11.6 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 OAP64753.1 - 0.057 12.9 0.3 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 OAP64753.1 - 0.099 12.9 0.1 0.4 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAP64753.1 - 0.13 12.2 0.8 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF106 PF01956.11 OAP64753.1 - 0.16 11.4 5.2 0.52 9.8 3.6 1.8 1 0 0 1 1 1 0 Integral membrane protein DUF106 Tim17 PF02466.14 OAP64754.1 - 4e-49 165.9 6.9 4e-49 165.9 4.8 1.7 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family ADH_zinc_N PF00107.21 OAP64755.1 - 5.6e-25 87.3 2.0 7e-25 87.0 0.4 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP64755.1 - 4.5e-22 77.8 1.4 1.2e-21 76.5 1.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP64755.1 - 0.029 15.2 0.2 0.052 14.4 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 OAP64755.1 - 0.13 12.8 0.1 0.33 11.5 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 OAP64756.1 - 3.2e-12 46.1 0.0 3.3e-11 42.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP64756.1 - 0.047 12.7 0.0 0.17 10.9 0.0 1.9 3 0 0 3 3 3 0 Protein tyrosine kinase Pex14_N PF04695.8 OAP64756.1 - 2.8 7.9 5.2 5.3 7.1 3.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ERF PF04404.7 OAP64756.1 - 8.4 5.9 10.7 16 4.9 7.4 1.4 1 0 0 1 1 1 0 ERF superfamily RNA_pol_Rpb2_6 PF00562.23 OAP64757.1 - 9.3e-119 396.6 0.0 1.5e-118 395.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAP64757.1 - 1.7e-53 180.5 0.2 4.7e-53 179.1 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 OAP64757.1 - 2.6e-27 94.9 0.3 1e-26 93.0 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 OAP64757.1 - 4.3e-27 94.7 0.4 1.1e-26 93.4 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 OAP64757.1 - 6.3e-22 77.1 0.2 1.4e-21 76.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 OAP64757.1 - 2.1e-19 69.0 0.0 5e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 OAP64757.1 - 1.4e-14 53.7 0.1 4.2e-14 52.2 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 PUF PF00806.14 OAP64758.1 - 5.3e-59 192.5 3.8 9.6e-10 37.4 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HCV_NS2 PF01538.13 OAP64758.1 - 0.25 10.7 0.1 0.58 9.5 0.0 1.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS2 ORC5_C PF14630.1 OAP64759.1 - 6.6e-53 179.9 0.0 2e-52 178.3 0.0 1.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 OAP64759.1 - 0.00092 19.2 0.1 0.0036 17.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain ATP-synt_ab PF00006.20 OAP64761.1 - 4.4e-109 363.0 0.0 5.9e-109 362.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.11 OAP64761.1 - 1.2e-65 221.3 0.0 1.7e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 OAP64761.1 - 2.9e-35 120.5 0.0 7.5e-32 109.5 0.0 2.5 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_C PF00306.22 OAP64761.1 - 7.8e-16 58.5 0.3 1.4e-15 57.7 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAP64761.1 - 4.2e-14 52.4 2.2 9.7e-14 51.3 1.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.1 OAP64761.1 - 3e-06 27.3 0.0 0.028 14.6 0.0 2.5 2 0 0 2 2 2 2 LAGLIDADG-like domain Hint_2 PF13403.1 OAP64761.1 - 0.00031 20.6 0.1 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 Hint domain Hint PF01079.15 OAP64761.1 - 0.00042 19.5 0.0 0.00081 18.6 0.0 1.4 1 0 0 1 1 1 1 Hint module HSBP1 PF06825.7 OAP64761.1 - 0.032 13.7 0.2 0.08 12.5 0.2 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 WD40 PF00400.27 OAP64762.1 - 2.6e-32 109.5 6.9 9.1e-09 34.8 0.4 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat DPPIV_N PF00930.16 OAP64762.1 - 0.0018 16.9 0.4 0.015 13.8 0.3 2.2 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF4221 PF13970.1 OAP64762.1 - 0.0041 16.4 0.0 0.053 12.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4221) DUF3312 PF11768.3 OAP64762.1 - 0.0042 15.3 0.0 0.0062 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) eIF2A PF08662.6 OAP64762.1 - 0.016 14.9 1.5 0.21 11.3 0.2 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 OAP64762.1 - 0.035 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 OAP64762.1 - 0.078 12.6 0.0 4.7 6.9 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Dynamin_M PF01031.15 OAP64763.1 - 4.7e-107 357.1 0.1 8.5e-107 356.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 OAP64763.1 - 2.7e-56 189.9 1.2 3.2e-56 189.7 0.1 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 OAP64763.1 - 1e-29 102.2 6.8 2.9e-29 100.8 4.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 OAP64763.1 - 6.3e-05 22.9 0.3 0.00041 20.2 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAP64763.1 - 0.0099 16.3 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 OAP64763.1 - 0.044 12.8 0.3 4.6 6.2 0.0 2.5 2 0 0 2 2 2 0 AIG1 family FeoB_N PF02421.13 OAP64763.1 - 0.076 12.2 0.6 6 6.1 0.1 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B SWIRM PF04433.12 OAP64765.1 - 0.0082 16.2 0.1 0.041 13.9 0.1 2.2 1 1 0 1 1 1 1 SWIRM domain DUF4066 PF13278.1 OAP64766.1 - 1.5e-18 66.6 0.1 1.7e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 OAP64766.1 - 0.00017 21.0 0.0 0.00046 19.6 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family PLDc_N PF13396.1 OAP64767.1 - 4.1e-12 45.5 2.5 9.5e-12 44.3 1.7 1.7 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal p450 PF00067.17 OAP64768.1 - 3e-50 171.0 0.0 3.6e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 OAP64769.1 - 1.3e-19 70.4 0.0 3.8e-19 68.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP64769.1 - 1.2e-11 45.1 0.0 1.1e-10 42.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP64769.1 - 1e-08 34.9 0.0 4.9e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP64769.1 - 7.4e-07 29.5 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP64769.1 - 3.1e-06 27.5 0.0 1.6e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP64769.1 - 5.9e-06 26.5 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAP64769.1 - 4e-05 22.8 0.0 8.4e-05 21.7 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 OAP64769.1 - 0.00019 21.4 0.0 0.0032 17.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAP64769.1 - 0.0011 19.0 0.1 0.0038 17.2 0.0 1.8 1 1 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 OAP64769.1 - 0.0068 15.7 0.0 0.033 13.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 OAP64769.1 - 0.026 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 OAP64769.1 - 0.029 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 OAP64769.1 - 0.034 13.2 0.0 0.071 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DJ-1_PfpI_N PF13587.1 OAP64769.1 - 0.35 10.4 2.4 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of DJ-1_PfpI family Arylsulfotran_2 PF14269.1 OAP64770.1 - 1.6e-60 204.8 0.6 2.6e-60 204.0 0.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAP64770.1 - 6.2e-11 41.4 0.4 1.5e-09 36.8 0.2 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) FAD_binding_3 PF01494.14 OAP64771.1 - 3e-21 75.8 0.0 5.6e-21 74.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP64771.1 - 3.5e-05 22.9 0.0 0.0047 15.8 0.0 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP64771.1 - 5.6e-05 23.0 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 OAP64771.1 - 6.2e-05 21.9 0.0 0.00027 19.8 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 OAP64771.1 - 0.00024 20.9 0.3 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAP64771.1 - 0.00082 18.5 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 OAP64771.1 - 0.012 14.2 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.19 OAP64771.1 - 0.018 13.9 0.1 0.056 12.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP64771.1 - 0.03 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP64771.1 - 0.081 12.9 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP64771.1 - 0.1 11.0 0.0 0.18 10.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Molybdopterin PF00384.17 OAP64772.1 - 4.9e-69 233.1 0.0 1e-66 225.5 0.0 2.4 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 OAP64772.1 - 2.9e-19 68.6 0.1 7.2e-19 67.3 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 OAP64772.1 - 1.1e-18 66.1 0.1 2.8e-18 64.8 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 OAP64772.1 - 4.1e-14 52.4 0.0 9.3e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 OAP64772.1 - 1e-08 34.8 0.5 1e-08 34.8 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 OAP64772.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Ank_5 PF13857.1 OAP64772.1 - 0.097 12.9 0.1 2.8 8.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) EXS PF03124.9 OAP64773.1 - 7.4e-88 294.8 31.4 9.3e-88 294.5 21.8 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 OAP64773.1 - 8e-47 160.3 0.0 4e-46 158.0 0.0 2.1 2 1 0 2 2 2 1 SPX domain DIOX_N PF14226.1 OAP64774.1 - 1.8e-27 96.1 0.0 7.8e-27 94.1 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP64774.1 - 1.8e-13 50.6 0.0 3.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SR-25 PF10500.4 OAP64774.1 - 6.1 6.2 8.8 9 5.6 6.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NmrA PF05368.8 OAP64775.1 - 3.9e-18 65.5 0.1 5.4e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP64775.1 - 1.5e-14 54.4 0.1 2.3e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 OAP64775.1 - 1.4e-10 40.7 0.2 2.4e-10 39.9 0.1 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 OAP64775.1 - 4.2e-06 26.3 0.0 4.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 OAP64775.1 - 6.8e-05 23.1 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 OAP64775.1 - 0.00035 19.6 0.3 0.00076 18.5 0.2 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.15 OAP64775.1 - 0.00056 19.8 0.1 0.00096 19.0 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 OAP64775.1 - 0.0018 18.6 0.1 0.0056 17.0 0.1 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAP64775.1 - 0.015 14.9 1.1 0.065 12.8 0.4 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 OAP64775.1 - 0.015 15.1 0.2 0.029 14.3 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_2 PF03446.10 OAP64775.1 - 0.026 14.3 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 OAP64775.1 - 0.033 14.4 0.2 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain LytR_C PF13399.1 OAP64775.1 - 0.038 14.3 0.7 0.24 11.7 0.4 2.3 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Ldh_1_N PF00056.18 OAP64775.1 - 0.043 13.6 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 OAP64775.1 - 0.052 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CbiJ PF02571.9 OAP64775.1 - 0.06 12.6 1.8 0.075 12.3 0.5 1.6 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK PGM_PMM_II PF02879.11 OAP64775.1 - 0.11 12.8 0.0 5.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DEDD_Tnp_IS110 PF01548.12 OAP64775.1 - 0.15 11.6 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Transposase NAD_Gly3P_dh_N PF01210.18 OAP64775.1 - 0.21 11.3 1.3 0.83 9.3 0.8 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ERCC4 PF02732.10 OAP64776.1 - 1.2e-09 38.1 0.1 2.8e-09 36.8 0.1 1.7 1 1 0 1 1 1 1 ERCC4 domain LSM PF01423.17 OAP64776.1 - 0.0014 18.1 0.2 0.28 10.7 0.0 2.7 2 0 0 2 2 2 2 LSM domain LETM1 PF07766.8 OAP64776.1 - 0.23 10.4 8.0 0.47 9.4 5.5 1.4 1 0 0 1 1 1 0 LETM1-like protein DUF3987 PF13148.1 OAP64776.1 - 4.5 5.7 9.4 0.72 8.3 3.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Glycos_transf_1 PF00534.15 OAP64777.1 - 1.2e-32 112.7 0.0 7.3e-23 80.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAP64777.1 - 3.9e-09 36.7 0.0 2.1e-07 31.1 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAP64777.1 - 2e-08 34.5 0.1 2.5e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 OAP64777.1 - 4.8e-07 29.9 0.0 9.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAP64777.1 - 7.4e-07 29.0 0.0 1.1e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_hydro_72 PF03198.9 OAP64778.1 - 5.8e-120 400.0 0.0 7.1e-120 399.7 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase DUF1206 PF06724.6 OAP64778.1 - 0.0085 15.8 0.2 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) MARVEL PF01284.18 OAP64779.1 - 0.0014 18.4 14.0 0.002 17.9 9.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain CTP_transf_1 PF01148.15 OAP64779.1 - 0.21 11.2 6.9 0.062 12.9 2.2 1.9 2 0 0 2 2 2 0 Cytidylyltransferase family DUF4234 PF14018.1 OAP64779.1 - 0.32 10.7 3.5 8.8 6.1 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) Flavokinase PF01687.12 OAP64780.1 - 3.3e-11 43.1 0.0 8.9e-11 41.7 0.0 1.6 1 1 1 2 2 2 1 Riboflavin kinase FAD_binding_3 PF01494.14 OAP64781.1 - 1.5e-14 53.8 0.0 2.9e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP64781.1 - 0.00056 18.9 0.1 0.065 12.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 OAP64781.1 - 0.018 13.8 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.9 OAP64781.1 - 0.034 12.7 0.3 9.3 4.7 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.22 OAP64781.1 - 0.1 13.0 0.1 19 5.7 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 OAP64782.1 - 2.2e-31 107.8 2.9 2.2e-31 107.8 2.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP64782.1 - 1.2e-24 86.3 1.7 1.2e-24 86.3 1.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 OAP64782.1 - 8.1e-05 22.7 0.1 0.00014 21.9 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAP64782.1 - 0.0043 17.2 1.0 0.012 15.8 0.3 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 OAP64782.1 - 0.0051 16.7 0.3 0.0082 16.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 OAP64782.1 - 0.024 15.0 0.2 0.055 13.8 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 OAP64782.1 - 0.025 14.6 0.2 0.052 13.6 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAP64782.1 - 0.033 14.5 2.1 0.94 9.9 1.6 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 OAP64782.1 - 0.058 13.3 0.5 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 OAP64782.1 - 0.11 12.4 2.1 0.15 12.0 1.1 1.4 2 0 0 2 2 2 0 NADH(P)-binding MFS_1 PF07690.11 OAP64783.1 - 2.9e-42 144.6 54.9 6.4e-42 143.5 35.8 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP64783.1 - 4.7e-12 45.2 17.1 4.7e-12 45.2 11.8 3.1 1 1 2 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 OAP64783.1 - 1.9e-10 39.5 26.0 3.6e-10 38.6 17.6 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pex14_N PF04695.8 OAP64783.1 - 0.48 10.4 2.3 1.3 9.1 1.6 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CENP-S PF15630.1 OAP64784.1 - 1.8e-32 111.3 0.0 2.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAP64784.1 - 0.00013 21.3 0.1 0.00017 21.0 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T PGA2 PF07543.7 OAP64785.1 - 1.8e-05 24.5 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF1446 PF07287.6 OAP64786.1 - 1.3e-119 398.8 0.0 1.6e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) RRM_1 PF00076.17 OAP64787.1 - 3.8e-45 151.3 0.0 7.8e-17 60.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP64787.1 - 1.2e-27 95.6 0.0 1.9e-09 37.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP64787.1 - 3.1e-21 74.9 0.0 2.5e-08 33.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAP64787.1 - 1.2e-05 25.0 0.0 9.6e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 OAP64787.1 - 2.8e-05 23.8 0.0 0.0084 15.8 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Acetyltransf_1 PF00583.19 OAP64788.1 - 0.00034 20.5 0.0 0.0012 18.8 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP64788.1 - 0.0005 20.1 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP64788.1 - 0.011 15.7 0.1 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Arf PF00025.16 OAP64789.1 - 2.7e-65 218.8 1.9 3e-65 218.7 1.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 OAP64789.1 - 1.1e-13 50.6 2.3 2.4e-08 33.0 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 OAP64789.1 - 5.7e-11 42.0 0.0 7.2e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 OAP64789.1 - 1.7e-10 40.5 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 OAP64789.1 - 3.3e-09 36.7 0.1 5.1e-09 36.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAP64789.1 - 2.6e-08 34.3 0.0 3.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 OAP64789.1 - 2e-07 30.6 0.0 2e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAP64789.1 - 1.2e-05 24.5 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 OAP64789.1 - 0.0017 17.6 0.7 0.0074 15.5 0.5 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.14 OAP64789.1 - 0.0032 16.9 0.1 0.2 11.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 OAP64789.1 - 0.012 16.4 0.1 0.015 16.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 OAP64789.1 - 0.035 13.7 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 OAP64789.1 - 0.056 12.9 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 OAP64789.1 - 0.088 11.8 0.1 0.19 10.8 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DUF4045 PF13254.1 OAP64790.1 - 1.8e-95 320.7 28.6 1.8e-95 320.7 19.8 5.7 3 2 1 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 OAP64790.1 - 2.3e-14 52.8 0.0 0.00059 19.4 0.0 4.3 4 0 0 4 4 4 3 Gelsolin repeat DUF2852 PF11014.3 OAP64790.1 - 0.25 11.2 0.1 0.72 9.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) ALO PF04030.9 OAP64791.1 - 2.5e-85 286.2 0.0 3.2e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 OAP64791.1 - 1.2e-24 86.3 0.0 2e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Sugar_tr PF00083.19 OAP64792.1 - 7.5e-87 291.7 23.3 9.4e-87 291.4 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP64792.1 - 2.9e-13 49.2 48.7 2.5e-08 33.0 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.18 OAP64793.1 - 1.7e-17 63.5 9.3 2.1e-17 63.3 6.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.3 OAP64793.1 - 0.031 13.7 1.8 0.037 13.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) PQ-loop PF04193.9 OAP64793.1 - 0.05 13.1 1.4 1.2 8.7 0.0 3.0 3 0 0 3 3 3 0 PQ loop repeat DUF588 PF04535.7 OAP64793.1 - 0.076 12.5 4.1 1.4 8.5 2.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF588) DUF202 PF02656.10 OAP64793.1 - 0.67 10.2 4.9 3.6 7.8 3.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Fungal_trans_2 PF11951.3 OAP64794.1 - 2.9e-10 39.3 0.4 5e-09 35.2 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 OAP64795.1 - 3.1e-81 273.7 0.0 3.8e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP64795.1 - 5.4e-05 22.8 0.6 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP64795.1 - 0.019 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4336 PF14234.1 OAP64796.1 - 2.4e-16 59.7 0.0 3.2e-13 49.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) 7TM_GPCR_Srh PF10318.4 OAP64797.1 - 0.089 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Patatin PF01734.17 OAP64799.1 - 2e-28 99.7 0.1 4.4e-28 98.6 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_5 PF14634.1 OAP64799.1 - 0.0012 18.5 6.4 0.0012 18.5 4.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAP64799.1 - 0.003 17.1 8.2 0.053 13.1 4.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 OAP64799.1 - 0.017 14.9 2.4 0.077 12.9 1.7 2.2 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.1 OAP64799.1 - 0.032 14.0 7.6 0.3 10.9 5.3 2.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 OAP64799.1 - 0.086 12.6 11.7 0.02 14.7 5.1 2.2 2 0 0 2 2 2 0 Ring finger domain PRP38 PF03371.10 OAP64800.1 - 6.5e-65 217.9 0.0 7.9e-65 217.6 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Dak1 PF02733.12 OAP64801.1 - 0.0017 16.9 0.4 0.011 14.3 0.3 2.0 1 1 0 1 1 1 1 Dak1 domain DUF3445 PF11927.3 OAP64802.1 - 6.1e-77 258.3 0.0 8.2e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Bac_rhamnosid_N PF08531.5 OAP64802.1 - 0.03 13.8 0.2 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain MMR_HSR1 PF01926.18 OAP64803.1 - 3.3e-14 52.8 0.0 6.2e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAP64803.1 - 2.5e-05 23.6 0.0 3.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 OAP64803.1 - 0.00057 19.1 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAP64803.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 OAP64803.1 - 0.0015 17.6 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.18 OAP64803.1 - 0.01 15.6 0.2 0.12 12.1 0.1 2.3 1 1 1 2 2 2 0 Dynamin family Miro PF08477.8 OAP64803.1 - 0.025 15.0 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Plasmid_RAQPRD PF09686.5 OAP64803.1 - 0.076 13.1 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) AAA_18 PF13238.1 OAP64803.1 - 0.1 12.9 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 OAP64803.1 - 0.12 12.0 0.1 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 OAP64803.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) WD40 PF00400.27 OAP64804.1 - 1.4e-36 123.0 28.7 9.8e-07 28.4 0.4 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat Rhomboid PF01694.17 OAP64805.1 - 3.6e-23 82.2 11.6 1.4e-22 80.2 6.2 2.1 1 1 1 2 2 2 1 Rhomboid family SseC PF04888.7 OAP64805.1 - 7.7 5.7 6.8 12 5.1 4.7 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Lactamase_B PF00753.22 OAP64806.1 - 1.1e-14 54.6 5.0 1.6e-14 54.0 3.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP64806.1 - 0.0073 15.8 1.9 0.01 15.4 1.3 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PGM_PMM_I PF02878.11 OAP64806.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Lipase_3 PF01764.20 OAP64807.1 - 9.8e-35 119.2 0.0 1.6e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 OAP64807.1 - 3.1e-09 36.5 0.1 5.4e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_5 PF12695.2 OAP64807.1 - 0.00025 20.8 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAP64807.1 - 0.0043 16.6 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 OAP64807.1 - 0.0047 16.8 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 OAP64807.1 - 0.0049 16.3 0.1 0.0096 15.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF2974 PF11187.3 OAP64807.1 - 0.021 14.2 0.4 0.075 12.3 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.17 OAP64807.1 - 0.032 13.9 0.1 0.032 13.9 0.1 1.8 2 0 0 2 2 2 0 Cutinase DUF676 PF05057.9 OAP64807.1 - 0.17 11.1 0.3 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 OAP64809.1 - 0.079 12.8 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Host_attach PF10116.4 OAP64810.1 - 0.042 14.0 0.6 0.042 14.0 0.4 2.9 2 1 1 3 3 3 0 Protein required for attachment to host cells WD40 PF00400.27 OAP64811.1 - 7.5e-22 76.3 9.7 2.7e-09 36.5 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 OAP64811.1 - 1.3e-18 66.5 0.0 2.8e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 OAP64811.1 - 0.013 13.6 2.2 0.02 13.0 0.2 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 OAP64811.1 - 0.015 15.0 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region adh_short PF00106.20 OAP64812.1 - 3.4e-27 95.3 0.1 5e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP64812.1 - 4.3e-26 92.1 0.3 5.4e-26 91.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP64812.1 - 9.4e-10 38.4 0.9 5.5e-09 35.9 0.6 1.9 1 1 0 1 1 1 1 KR domain zf-HIT PF04438.11 OAP64813.1 - 2e-10 40.1 6.7 4e-10 39.1 4.6 1.5 1 0 0 1 1 1 1 HIT zinc finger Tnp_zf-ribbon_2 PF13842.1 OAP64813.1 - 5.8 7.4 11.6 16 6.0 8.0 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DENN PF02141.16 OAP64814.1 - 8.2e-40 136.5 0.1 1.5e-39 135.6 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 OAP64814.1 - 0.0006 19.7 0.3 0.0019 18.1 0.0 2.0 2 0 0 2 2 2 1 uDENN domain SMC_Nse1 PF07574.8 OAP64814.1 - 0.0018 17.9 1.3 0.0043 16.7 0.9 1.6 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex GxGYxYP PF14323.1 OAP64814.1 - 0.29 9.8 2.9 0.15 10.7 0.2 1.8 2 0 0 2 2 2 0 GxGYxY sequence motif in domain of unknown function DivIC PF04977.10 OAP64814.1 - 0.38 10.2 17.1 3.3 7.2 1.8 3.7 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.3 OAP64814.1 - 2.5 8.0 18.9 0.68 9.8 3.8 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 OAP64814.1 - 2.7 8.1 9.4 2.4 8.3 0.5 3.4 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 OAP64814.1 - 2.9 7.9 9.1 0.61 10.2 1.5 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 OAP64814.1 - 4.1 6.6 18.4 0.18 11.0 2.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) SlyX PF04102.7 OAP64814.1 - 4.2 7.8 13.4 4.4 7.7 0.7 3.3 2 1 0 2 2 2 0 SlyX Microtub_assoc PF07989.6 OAP64814.1 - 4.5 7.1 8.3 0.3 10.9 1.3 2.4 2 1 0 2 2 2 0 Microtubule associated 3HCDH_N PF02737.13 OAP64815.1 - 1.3e-22 80.3 0.0 9.5e-12 44.9 0.0 2.3 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 OAP64815.1 - 9.4e-11 41.9 0.0 2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 OAP64815.1 - 0.07 12.9 0.0 0.47 10.2 0.0 2.1 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pkinase PF00069.20 OAP64816.1 - 1.1e-21 77.1 0.0 1.9e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 OAP64816.1 - 1.5e-13 50.0 1.1 1.4e-08 34.2 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.17 OAP64816.1 - 2.2e-11 42.8 7.5 0.007 16.3 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 OAP64816.1 - 1.7e-08 34.6 1.8 0.029 14.6 0.1 4.2 4 1 1 5 5 5 3 HEAT repeats Pkinase_Tyr PF07714.12 OAP64816.1 - 0.001 18.1 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 OAP64816.1 - 0.012 16.0 4.1 0.89 10.1 0.4 3.9 3 1 0 3 3 3 0 HEAT-like repeat RabGAP-TBC PF00566.13 OAP64817.1 - 6.2e-38 130.4 0.0 1.8e-37 128.8 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TilS_C PF11734.3 OAP64817.1 - 0.033 13.4 0.0 0.12 11.5 0.0 1.9 1 0 0 1 1 1 0 TilS substrate C-terminal domain PLDc PF00614.17 OAP64818.1 - 3e-14 52.2 0.2 3e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 OAP64818.1 - 7.6e-13 48.3 0.0 2.6e-06 27.2 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain Abhydrolase_6 PF12697.2 OAP64819.1 - 0.00019 21.4 0.1 0.00037 20.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 OAP64819.1 - 0.00095 18.2 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 OAP64819.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pex2_Pex12 PF04757.9 OAP64820.1 - 3.8e-51 173.7 0.8 5.2e-51 173.2 0.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 OAP64820.1 - 0.0038 17.0 0.8 0.0067 16.2 0.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP64820.1 - 0.02 14.8 0.8 0.035 14.1 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAP64820.1 - 0.08 12.8 0.6 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TEX19 PF15553.1 OAP64820.1 - 0.14 12.0 1.4 0.28 11.0 1.0 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 Rhabdo_ncap PF00945.13 OAP64820.1 - 0.42 9.1 1.4 1.3 7.4 1.2 1.5 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein Dynamin_N PF00350.18 OAP64821.1 - 2.7e-28 98.9 0.0 1.6e-27 96.3 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 OAP64821.1 - 1.7e-10 40.1 0.1 2.8e-09 36.1 0.1 2.5 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 OAP64821.1 - 7.4e-06 25.9 0.0 2.6e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 OAP64821.1 - 0.0015 18.5 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 OAP64821.1 - 0.0078 16.6 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_23 PF13476.1 OAP64821.1 - 0.019 15.2 0.5 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3886 PF13025.1 OAP64821.1 - 0.058 13.3 7.2 0.23 11.4 5.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) AAA_29 PF13555.1 OAP64821.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UBA PF00627.26 OAP64822.1 - 0.003 17.3 0.1 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain bZIP_1 PF00170.16 OAP64823.1 - 6.1e-08 32.5 10.2 1.1e-07 31.6 7.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAP64823.1 - 4.5e-05 23.1 10.0 8.3e-05 22.3 6.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper 3HCDH_N PF02737.13 OAP64823.1 - 0.022 14.4 2.4 0.031 13.9 1.7 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain bZIP_Maf PF03131.12 OAP64823.1 - 0.088 13.1 9.7 0.067 13.4 5.2 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor QueT PF06177.6 OAP64824.1 - 0.046 13.6 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 QueT transporter Pkinase PF00069.20 OAP64825.1 - 6.6e-37 127.0 0.0 4e-25 88.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP64825.1 - 6.7e-15 54.8 0.0 9.4e-08 31.4 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAP64825.1 - 0.028 13.3 0.0 5.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like NMD3 PF04981.8 OAP64826.1 - 1.2e-75 253.6 3.2 1.8e-75 253.1 2.2 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 OAP64826.1 - 2.2 8.1 6.8 27 4.6 2.9 2.8 2 1 0 2 2 2 0 Double zinc ribbon ECH_C PF13766.1 OAP64827.1 - 1.5e-35 121.8 0.3 3.6e-35 120.6 0.2 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 OAP64827.1 - 5.5e-27 94.4 0.0 4.2e-26 91.5 0.0 2.0 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family KfrA_N PF11740.3 OAP64827.1 - 0.0035 17.7 1.4 0.058 13.8 0.0 3.0 3 0 0 3 3 3 1 Plasmid replication region DNA-binding N-term RRM_6 PF14259.1 OAP64828.1 - 0.00053 19.8 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP64828.1 - 0.0016 18.0 0.0 0.0081 15.7 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP64828.1 - 0.046 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SGT1 PF07093.6 OAP64828.1 - 0.18 10.1 16.0 0.31 9.3 11.1 1.3 1 0 0 1 1 1 0 SGT1 protein RXT2_N PF08595.6 OAP64828.1 - 3.9 7.2 12.1 0.48 10.2 4.7 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Glyco_hydro_47 PF01532.15 OAP64829.1 - 2.6e-171 570.2 0.0 3e-171 570.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_17 PF00332.13 OAP64830.1 - 2.3e-08 33.4 2.3 6.6e-08 31.9 1.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 CoaE PF01121.15 OAP64831.1 - 1.6e-39 135.1 0.0 2.1e-21 76.1 0.0 2.0 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_17 PF13207.1 OAP64831.1 - 0.013 16.2 0.2 0.074 13.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAP64831.1 - 0.042 14.1 0.3 0.78 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain PolyA_pol PF01743.15 OAP64832.1 - 3.5e-23 82.2 1.8 1.3e-22 80.3 1.2 2.0 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 OAP64832.1 - 0.00018 20.9 0.0 0.00069 19.1 0.0 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Acyl-CoA_dh_1 PF00441.19 OAP64833.1 - 5.8e-29 101.1 0.4 7.9e-29 100.6 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP64833.1 - 9.5e-22 76.2 0.6 1.7e-21 75.4 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAP64833.1 - 6.7e-21 74.9 0.0 2.1e-20 73.4 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAP64833.1 - 4.2e-06 27.0 0.1 7.6e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Syja_N PF02383.13 OAP64834.1 - 9.7e-91 303.8 0.1 2.2e-90 302.6 0.1 1.6 1 0 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 OAP64835.1 - 4.5e-52 176.8 1.2 5.6e-52 176.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) MatE PF01554.13 OAP64836.1 - 6.6e-55 185.1 18.9 1.9e-29 102.4 2.8 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 OAP64836.1 - 1.1e-05 25.2 5.8 1.1e-05 25.2 4.0 3.8 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.16 OAP64837.1 - 3.1e-87 292.4 0.0 4e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 OAP64837.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 UPF0489 domain Metallophos PF00149.23 OAP64838.1 - 5.8e-44 149.8 0.9 7.4e-44 149.5 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MmgE_PrpD PF03972.9 OAP64839.1 - 2.2e-63 213.9 0.0 3.1e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family DUF4387 PF14330.1 OAP64840.1 - 2.9e-33 114.1 0.0 4e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1890 PF09001.6 OAP64840.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) DUF1446 PF07287.6 OAP64841.1 - 0.00018 20.0 0.0 0.00076 18.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) TauD PF02668.11 OAP64842.1 - 6e-29 101.4 0.0 7.7e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 OAP64842.1 - 0.026 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 CsiD Tet_JBP PF12851.2 OAP64842.1 - 0.031 13.5 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Podoplanin PF05808.6 OAP64844.1 - 0.048 13.2 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Podoplanin TRI12 PF06609.8 OAP64845.1 - 2.7e-14 52.2 7.7 3.1e-14 52.0 5.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP64845.1 - 7.2e-07 28.2 9.3 7.2e-07 28.2 6.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP64846.1 - 3.8e-16 58.4 5.4 4.5e-16 58.1 3.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 OAP64846.1 - 0.00083 18.1 8.4 0.00083 18.1 5.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Spore_YtrH PF14034.1 OAP64846.1 - 6.4 6.7 8.2 13 5.7 1.3 3.0 3 0 0 3 3 3 0 Sporulation protein YtrH PI31_Prot_N PF11566.3 OAP64847.1 - 9e-31 106.5 0.0 1.1e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 OAP64847.1 - 6.6e-16 58.7 19.4 6.6e-16 58.7 13.5 3.0 3 1 1 4 4 4 1 PI31 proteasome regulator DUF2763 PF10961.3 OAP64847.1 - 8.3 6.8 0.0 8.3 6.8 0.0 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF2763) DUF3112 PF11309.3 OAP64848.1 - 2.6e-18 66.3 12.7 4.5e-17 62.3 2.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Sad1_UNC PF07738.8 OAP64849.1 - 1.6e-11 44.1 0.0 7.7e-10 38.6 0.0 2.4 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Mer2 PF09074.5 OAP64849.1 - 0.15 11.9 6.2 0.07 13.0 0.7 2.2 2 0 0 2 2 2 0 Mer2 TFIIA PF03153.8 OAP64849.1 - 0.17 11.7 10.1 0.28 11.0 7.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Baculo_PEP_C PF04513.7 OAP64849.1 - 0.56 10.0 5.9 2.6 7.8 0.5 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short PF00106.20 OAP64850.1 - 6.8e-17 61.8 1.1 2.5e-16 60.0 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 OAP64850.1 - 0.0021 17.5 0.0 0.005 16.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP64850.1 - 0.0051 16.8 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 OAP64850.1 - 0.012 15.2 1.3 0.066 12.8 0.0 2.6 3 0 0 3 3 3 0 KR domain 3Beta_HSD PF01073.14 OAP64850.1 - 0.024 13.3 0.0 0.039 12.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family tRNA_bind PF01588.15 OAP64851.1 - 9.8e-19 66.9 0.1 1.6e-16 59.9 0.1 2.3 1 1 0 1 1 1 1 Putative tRNA binding domain SNARE PF05739.14 OAP64852.1 - 3.5e-13 49.0 2.1 7.2e-13 48.0 1.5 1.6 1 0 0 1 1 1 1 SNARE domain zf-C3HC4 PF00097.20 OAP64853.1 - 1e-08 34.6 7.6 1e-08 34.6 5.2 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAP64853.1 - 1.3e-08 34.6 8.7 1.3e-08 34.6 6.0 3.6 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP64853.1 - 1.4e-08 34.2 5.2 1.4e-08 34.2 3.6 3.2 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP64853.1 - 1.4e-08 34.3 8.0 1.4e-08 34.3 5.6 4.1 3 2 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 OAP64853.1 - 4.7e-08 32.6 7.4 4.7e-08 32.6 5.1 3.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAP64853.1 - 2.3e-07 30.5 9.5 2.3e-07 30.5 6.6 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-TRAF PF02176.13 OAP64853.1 - 2.3e-06 27.8 23.3 3.8e-05 23.9 4.2 3.6 1 1 3 4 4 4 3 TRAF-type zinc finger zf-RING_UBOX PF13445.1 OAP64853.1 - 2.8e-06 26.9 4.0 2.8e-06 26.9 2.8 2.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_4 PF14570.1 OAP64853.1 - 0.011 15.3 2.0 0.011 15.3 1.4 4.5 5 1 1 6 6 6 0 RING/Ubox like zinc-binding domain NPV_P10 PF05531.7 OAP64853.1 - 0.14 12.4 0.6 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-RING_3 PF14369.1 OAP64853.1 - 0.33 10.9 9.8 0.61 10.1 0.0 4.1 3 0 0 3 3 3 0 zinc-finger Pkip-1 PF06878.6 OAP64853.1 - 0.5 10.2 2.4 0.87 9.4 0.1 2.1 2 0 0 2 2 2 0 Pkip-1 protein PspA_IM30 PF04012.7 OAP64853.1 - 2.2 7.5 5.9 0.14 11.4 0.2 1.8 2 1 1 3 3 3 0 PspA/IM30 family Pyridox_ox_2 PF12900.2 OAP64854.1 - 3.8e-31 107.8 0.0 1.3e-30 106.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ATP-synt_F6 PF05511.6 OAP64854.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 TFIIA_gamma_C PF02751.9 OAP64857.1 - 2.6e-26 91.1 0.9 3.4e-26 90.7 0.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 OAP64857.1 - 5.6e-25 86.6 0.2 7.9e-25 86.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Porin_OmpG PF09381.5 OAP64857.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) DUF4319 PF14203.1 OAP64858.1 - 0.042 13.3 2.0 0.064 12.8 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) DUF3391 PF11871.3 OAP64858.1 - 0.063 13.4 1.1 0.083 13.1 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) SGS PF05002.10 OAP64858.1 - 0.19 11.5 4.2 0.28 10.9 2.9 1.2 1 0 0 1 1 1 0 SGS domain GILT PF03227.11 OAP64859.1 - 3.4e-11 42.9 0.3 6.8e-11 41.9 0.1 1.7 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF3394 PF11874.3 OAP64859.1 - 0.007 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3394) Hexokinase_1 PF00349.16 OAP64860.1 - 6.8e-26 90.8 0.0 2.1e-24 85.9 0.0 2.7 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 OAP64860.1 - 6e-21 74.7 0.0 1.1e-16 60.7 0.0 2.2 2 0 0 2 2 2 2 Hexokinase DHC_N1 PF08385.7 OAP64862.1 - 3.9e-170 567.0 7.2 3.9e-170 567.0 5.0 5.0 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 OAP64862.1 - 1.1e-127 425.9 5.4 1.1e-127 425.9 3.7 4.6 4 1 1 5 5 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 OAP64862.1 - 8.2e-105 351.3 1.7 5.9e-104 348.5 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 OAP64862.1 - 8.4e-78 261.0 0.0 1.8e-77 259.9 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 OAP64862.1 - 6.4e-40 136.3 0.1 2.8e-39 134.3 0.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 OAP64862.1 - 6.3e-39 133.5 0.0 6.5e-38 130.2 0.0 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 OAP64862.1 - 7.9e-30 103.7 19.2 9.3e-23 80.5 0.9 2.9 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 OAP64862.1 - 3.6e-28 98.0 1.2 2.5e-10 40.2 0.0 6.8 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 OAP64862.1 - 7.5e-20 71.1 0.0 3.3e-19 69.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 OAP64862.1 - 4.1e-13 49.6 0.0 0.00024 21.3 0.0 5.0 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP64862.1 - 7.6e-13 48.7 0.5 0.039 14.1 0.0 6.6 6 1 1 7 7 5 3 AAA domain AAA_33 PF13671.1 OAP64862.1 - 2.1e-09 37.4 0.1 0.49 10.2 0.0 5.3 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 OAP64862.1 - 6.4e-09 36.6 0.7 0.038 14.8 0.0 6.5 6 0 0 6 6 5 1 AAA domain AAA_18 PF13238.1 OAP64862.1 - 2.1e-07 31.2 4.4 0.04 14.2 0.0 5.7 6 0 0 6 6 6 2 AAA domain ABC_tran PF00005.22 OAP64862.1 - 1.3e-05 25.5 0.1 2.5 8.3 0.0 5.6 4 0 0 4 4 4 1 ABC transporter AAA_14 PF13173.1 OAP64862.1 - 3.5e-05 23.6 0.0 0.31 10.9 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 OAP64862.1 - 5.8e-05 22.5 0.0 0.71 9.4 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 OAP64862.1 - 8.3e-05 22.1 0.0 4 6.8 0.0 3.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_19 PF13245.1 OAP64862.1 - 0.00027 20.6 0.1 1.2 8.9 0.0 3.9 3 0 0 3 3 3 1 Part of AAA domain Mg_chelatase PF01078.16 OAP64862.1 - 0.00033 19.8 0.6 0.64 9.1 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 OAP64862.1 - 0.00056 19.9 17.6 0.15 12.0 0.1 8.2 8 1 1 9 9 8 1 AAA ATPase domain DUF258 PF03193.11 OAP64862.1 - 0.012 14.8 0.0 20 4.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF258 MobB PF03205.9 OAP64862.1 - 0.027 14.1 0.5 12 5.6 0.1 3.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 OAP64862.1 - 0.037 13.5 0.8 3.2 7.2 0.1 3.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 OAP64862.1 - 0.79 9.0 11.1 2.1 7.7 0.0 5.8 6 1 1 7 7 6 0 AAA-like domain Sec7 PF01369.15 OAP64863.1 - 1.3e-58 197.7 0.0 2.1e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 OAP64863.1 - 1.2e-20 73.5 0.1 7e-14 51.5 0.2 3.1 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Ribonuclease_3 PF00636.21 OAP64864.1 - 2.9e-33 114.7 0.0 1.9e-15 57.2 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAP64864.1 - 6e-20 71.5 0.0 1.5e-07 31.4 0.0 4.1 3 1 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 OAP64864.1 - 4.6e-16 58.4 0.0 1e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP64864.1 - 1.4e-13 51.1 0.6 3.5e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAP64864.1 - 3.4e-13 49.4 0.0 6.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 OAP64864.1 - 5.7e-08 32.4 0.0 7.8e-07 28.7 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain DUF1476 PF07345.6 OAP64864.1 - 0.0012 19.0 0.1 0.0039 17.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1476) DUF3391 PF11871.3 OAP64864.1 - 0.0044 17.2 0.6 0.011 15.9 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) AAA_22 PF13401.1 OAP64864.1 - 0.005 16.9 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 OAP64864.1 - 0.01 14.6 0.1 0.027 13.2 0.1 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_26 PF13500.1 OAP64864.1 - 0.27 10.8 0.6 0.56 9.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain EF-hand_6 PF13405.1 OAP64865.1 - 9.9e-08 31.2 1.3 0.0022 17.7 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 OAP64865.1 - 0.0015 18.6 0.9 0.0057 16.7 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 OAP64865.1 - 0.0052 16.0 0.0 0.26 10.6 0.0 2.4 2 0 0 2 2 2 1 EF hand Met_10 PF02475.11 OAP64866.1 - 0.00088 18.9 0.0 0.0019 17.8 0.0 1.5 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 OAP64866.1 - 0.0079 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Mannosyl_trans3 PF11051.3 OAP64867.1 - 1.9e-68 230.7 0.0 2.8e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative MFS_1 PF07690.11 OAP64868.1 - 1.2e-25 90.0 42.2 1.4e-18 66.7 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dynamin_N PF00350.18 OAP64869.1 - 2.6e-16 59.8 0.4 1.6e-15 57.3 0.0 2.4 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 OAP64869.1 - 1.1e-05 25.3 0.0 0.0059 16.5 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 OAP64869.1 - 6e-05 23.3 0.0 0.00029 21.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 OAP64869.1 - 0.00094 18.3 0.4 0.023 13.8 0.0 3.0 3 0 0 3 3 3 1 AIG1 family DUF258 PF03193.11 OAP64869.1 - 0.0018 17.5 0.0 0.021 14.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAP64869.1 - 0.0092 15.9 0.2 0.098 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 OAP64869.1 - 0.016 15.7 0.1 0.093 13.2 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 OAP64869.1 - 0.034 14.3 0.4 3.4 7.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 OAP64869.1 - 0.039 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain HCMV_UL139 PF12507.3 OAP64869.1 - 0.064 13.4 4.1 0.049 13.7 1.2 2.0 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein FeoB_N PF02421.13 OAP64869.1 - 0.072 12.3 0.0 3.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.1 OAP64869.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.2 4 1 0 4 4 2 0 AAA domain DUF87 PF01935.12 OAP64869.1 - 6.2 6.5 10.0 0.39 10.4 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function DUF87 WD40 PF00400.27 OAP64870.1 - 9.2e-07 28.5 0.3 0.00027 20.7 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 OAP64870.1 - 0.0025 16.6 0.0 0.049 12.4 0.0 2.2 2 0 0 2 2 2 1 Coatomer WD associated region Apc4_WD40 PF12894.2 OAP64870.1 - 0.11 11.9 0.0 10 5.7 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_mis_repair PF01119.14 OAP64871.1 - 2e-32 111.1 0.0 3.5e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 OAP64871.1 - 4.3e-14 52.3 0.0 1.4e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAP64871.1 - 1.5e-10 40.7 0.0 8.8e-09 35.0 0.0 2.9 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_cc PF11790.3 OAP64872.1 - 3.7e-42 144.3 1.2 6.5e-42 143.5 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MOR2-PAG1_N PF14222.1 OAP64873.1 - 9.3e-171 569.2 0.0 1.8e-170 568.3 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 OAP64873.1 - 1.5e-83 280.5 0.2 4.2e-83 279.1 0.1 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 OAP64873.1 - 8.2e-32 109.8 20.4 8.1e-13 46.9 0.4 3.8 1 1 1 3 3 3 3 Cell morphogenesis central region DUF2258 PF10015.4 OAP64873.1 - 0.058 13.2 0.0 3.1 7.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) FAD_binding_1 PF00667.15 OAP64874.1 - 2.8e-64 216.5 0.0 4.3e-64 215.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAP64874.1 - 7.4e-36 123.2 0.6 1.8e-35 122.0 0.4 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAP64874.1 - 2.1e-22 79.7 0.1 1.6e-21 76.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 OAP64874.1 - 0.014 15.4 0.0 0.042 13.8 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain Arch_ATPase PF01637.13 OAP64874.1 - 0.079 12.6 0.4 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Kinetochor_Ybp2 PF08568.5 OAP64875.1 - 3.5e-73 246.9 0.5 5.5e-72 242.9 0.0 2.2 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin DEAD PF00270.24 OAP64877.1 - 3.1e-43 147.1 0.0 5.6e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 OAP64877.1 - 2.1e-26 91.2 0.0 4.2e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 OAP64877.1 - 8.1e-20 70.4 0.0 1.9e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DnaJ PF00226.26 OAP64878.1 - 1.6e-14 53.3 0.6 6.3e-14 51.4 0.4 2.1 1 0 0 1 1 1 1 DnaJ domain PAPS_reduct PF01507.14 OAP64880.1 - 3.9e-21 75.6 0.0 4.8e-17 62.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.27 OAP64881.1 - 3.6e-158 508.5 58.1 1.8e-14 52.9 0.4 11.7 11 0 0 11 11 11 11 WD domain, G-beta repeat NACHT PF05729.7 OAP64881.1 - 5.5e-22 78.1 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 OAP64881.1 - 7.9e-22 77.9 7.3 1.6e-19 70.4 5.0 2.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 OAP64881.1 - 3e-16 58.6 40.5 0.0026 15.9 4.9 10.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 BLUF PF04940.7 OAP64881.1 - 1.7e-06 27.6 0.0 29 4.4 0.0 8.4 9 0 0 9 9 9 0 Sensors of blue-light using FAD Asp_decarbox PF02261.11 OAP64881.1 - 1.3e-05 24.7 0.0 37 3.9 0.0 7.1 2 1 5 8 8 8 0 Aspartate decarboxylase Cytochrom_D1 PF02239.11 OAP64881.1 - 0.00051 18.4 4.3 6.7 4.8 0.1 4.7 3 1 2 5 5 5 2 Cytochrome D1 heme domain AAA_16 PF13191.1 OAP64881.1 - 0.0047 16.9 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Imm26 PF15572.1 OAP64881.1 - 0.018 15.1 0.1 17 5.6 0.0 4.6 5 1 0 5 5 5 0 Immunity protein 26 AAA_22 PF13401.1 OAP64881.1 - 0.027 14.6 0.0 0.094 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAP64881.1 - 0.14 11.8 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Polysacc_deac_1 PF01522.16 OAP64882.1 - 4.7e-24 84.3 0.0 7.8e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 OAP64882.1 - 5.4e-08 32.5 0.0 8.3e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.10 OAP64882.1 - 0.0032 16.4 0.1 0.0049 15.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 2-Hacid_dh_C PF02826.14 OAP64883.1 - 7.5e-38 129.4 0.0 5.2e-37 126.7 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP64883.1 - 1.6e-12 47.0 0.0 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP64883.1 - 0.00064 19.5 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAP64883.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAP64883.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAT PF03417.11 OAP64884.1 - 4e-29 101.6 0.0 9.9e-29 100.3 0.0 1.5 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Fungal_trans PF04082.13 OAP64885.1 - 1.2e-31 109.5 0.2 2e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64885.1 - 1.1e-07 31.6 9.6 1.7e-07 30.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.17 OAP64886.1 - 3.2e-40 137.5 0.0 3.7e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peripla_BP_1 PF00532.16 OAP64886.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family TPR_10 PF13374.1 OAP64886.1 - 0.067 13.1 1.0 0.19 11.7 0.7 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAP64886.1 - 0.067 13.8 0.4 0.2 12.3 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 OAP64887.1 - 2e-72 244.1 0.0 2.6e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAP64887.1 - 0.042 12.9 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Hydantoinase_B PF02538.9 OAP64888.1 - 1.3e-186 620.8 0.0 1.8e-186 620.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 OAP64888.1 - 3.4e-84 282.3 0.0 5.5e-84 281.6 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 OAP64888.1 - 1e-50 171.6 0.1 1.1e-48 165.0 0.0 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 OAP64889.1 - 1.6e-41 142.1 29.3 1.6e-41 142.1 20.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 OAP64889.1 - 0.00016 21.2 2.0 0.00016 21.2 1.4 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Mito_carr PF00153.22 OAP64890.1 - 1.7e-58 194.3 0.3 1.4e-19 69.5 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Git3 PF11710.3 OAP64891.1 - 6.8e-61 205.3 18.3 6.8e-61 205.3 12.7 1.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 OAP64891.1 - 6.5e-25 86.6 2.4 2.3e-24 84.9 1.7 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 OAP64891.1 - 4.4e-06 26.0 0.0 8.9e-06 25.0 0.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PNTB PF02233.11 OAP64891.1 - 0.013 14.3 1.3 0.02 13.7 0.9 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit MT-A70 PF05063.9 OAP64892.1 - 5.9e-26 91.0 0.0 8.5e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Peptidase_C12 PF01088.16 OAP64893.1 - 1.1e-63 214.2 0.0 1.3e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 OAP64893.1 - 0.04 14.5 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain Phage_Mu_F PF04233.9 OAP64893.1 - 0.045 14.2 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Phage Mu protein F like protein Oligomerisation PF02410.10 OAP64894.1 - 8.3e-05 22.5 0.0 0.052 13.5 0.0 2.5 2 1 0 2 2 2 2 Oligomerisation domain Pkip-1 PF06878.6 OAP64895.1 - 0.00026 20.9 2.6 0.00047 20.0 1.8 1.3 1 0 0 1 1 1 1 Pkip-1 protein IncA PF04156.9 OAP64895.1 - 0.072 12.6 19.0 0.028 14.0 11.0 1.7 1 1 1 2 2 2 0 IncA protein FHIPEP PF00771.15 OAP64895.1 - 0.11 10.7 5.6 0.14 10.4 3.9 1.1 1 0 0 1 1 1 0 FHIPEP family MtrG PF04210.8 OAP64895.1 - 0.59 9.8 2.1 1.9 8.2 0.1 2.8 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G TMF_DNA_bd PF12329.3 OAP64895.1 - 1.1 9.0 12.8 0.18 11.6 4.8 2.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ERM PF00769.14 OAP64895.1 - 1.2 8.5 20.6 3.3 7.1 14.0 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CHD5 PF04420.9 OAP64895.1 - 2.5 7.7 5.5 14 5.3 0.1 2.3 2 0 0 2 2 2 0 CHD5-like protein TBPIP PF07106.8 OAP64895.1 - 2.7 7.4 11.2 0.69 9.4 4.6 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 OAP64895.1 - 5.5 6.8 16.4 0.91 9.4 3.3 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 OAP64895.1 - 9 4.0 10.9 15 3.2 7.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Hist_deacetyl PF00850.14 OAP64896.1 - 1e-90 304.2 0.0 1.6e-90 303.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 OAP64896.1 - 9.6e-36 122.8 0.0 1.8e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Arb2 domain B-block_TFIIIC PF04182.7 OAP64896.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Gp_dh_C PF02800.15 OAP64897.1 - 6.4e-75 249.8 0.0 9.2e-75 249.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 OAP64897.1 - 3.9e-60 202.1 0.1 7.2e-60 201.3 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 OAP64897.1 - 0.011 15.6 0.1 0.04 13.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Pho88 PF10032.4 OAP64898.1 - 3.7e-81 270.9 0.0 4.2e-81 270.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CitMHS PF03600.11 OAP64898.1 - 0.015 13.8 0.3 0.018 13.6 0.2 1.0 1 0 0 1 1 1 0 Citrate transporter DUF1368 PF07112.6 OAP64898.1 - 0.056 12.0 0.1 0.08 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) NUDIX_2 PF13869.1 OAP64899.1 - 6.2e-80 266.9 0.0 7.3e-80 266.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M16 PF00675.15 OAP64900.1 - 3.9e-30 104.5 2.2 1.4e-29 102.7 0.8 2.4 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAP64900.1 - 4e-29 101.6 0.6 6.3e-19 68.3 0.0 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain DUF945 PF06097.6 OAP64900.1 - 0.03 13.1 0.1 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Abhydrolase_6 PF12697.2 OAP64902.1 - 2.7e-25 89.5 0.0 3.6e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP64902.1 - 3.4e-18 66.0 0.0 1.5e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP64902.1 - 1.9e-14 53.6 0.0 3.6e-14 52.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAP64902.1 - 0.00024 20.6 0.0 0.11 11.8 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase PhoPQ_related PF10142.4 OAP64902.1 - 0.0015 17.1 0.0 0.0028 16.2 0.0 1.4 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S9 PF00326.16 OAP64902.1 - 0.0086 15.3 0.0 0.59 9.3 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 OAP64902.1 - 0.0095 15.2 0.0 0.55 9.4 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 OAP64902.1 - 0.064 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.9 OAP64902.1 - 0.064 11.7 0.0 0.2 10.1 0.0 1.8 2 0 0 2 2 2 0 Ndr family Abhydrolase_4 PF08386.5 OAP64902.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein adh_short PF00106.20 OAP64904.1 - 2.9e-14 53.3 0.0 4.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP64904.1 - 3.6e-09 36.5 0.0 5.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP64904.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2388 PF09498.5 OAP64904.1 - 0.028 14.0 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Shikimate_DH PF01488.15 OAP64904.1 - 0.043 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ras PF00071.17 OAP64905.1 - 3.9e-31 107.6 0.1 5e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAP64905.1 - 2.4e-20 73.1 0.1 9.2e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 OAP64905.1 - 1.1e-06 27.9 0.1 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAP64905.1 - 7.4e-06 25.2 0.2 1e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.6 OAP64905.1 - 0.023 13.3 0.2 4.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.18 OAP64905.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 OAP64905.1 - 0.17 10.5 0.1 0.17 10.5 0.0 2.3 1 1 2 3 3 3 0 G-protein alpha subunit Pex14_N PF04695.8 OAP64905.1 - 0.19 11.7 8.2 0.46 10.5 5.7 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 OAP64905.1 - 6.1 6.1 12.1 8.5 5.6 8.4 1.2 1 0 0 1 1 1 0 Vta1 like DUF202 PF02656.10 OAP64906.1 - 1.3e-20 73.3 3.8 2.6e-20 72.4 0.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) TM140 PF14985.1 OAP64906.1 - 0.013 15.1 0.3 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 TM140 protein family Acyl_transf_3 PF01757.17 OAP64906.1 - 0.015 14.1 0.9 0.023 13.5 0.4 1.4 1 1 0 1 1 1 0 Acyltransferase family 2TM PF13239.1 OAP64906.1 - 0.03 14.3 0.3 0.067 13.2 0.1 1.6 1 1 0 1 1 1 0 2TM domain DUF373 PF04123.8 OAP64906.1 - 0.07 12.1 0.3 0.088 11.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Yip1 PF04893.12 OAP64906.1 - 0.32 10.5 5.3 0.12 11.8 0.9 1.9 1 1 1 2 2 2 0 Yip1 domain DUF1345 PF07077.6 OAP64906.1 - 0.46 9.9 3.6 2.1 7.8 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Tetraspannin PF00335.15 OAP64906.1 - 1.1 8.5 6.0 0.34 10.1 2.0 1.6 1 1 1 2 2 2 0 Tetraspanin family MatE PF01554.13 OAP64907.1 - 3.7e-57 192.4 27.4 2.6e-30 105.1 7.7 2.3 2 0 0 2 2 2 2 MatE NUDIX PF00293.23 OAP64908.1 - 7.8e-28 96.8 0.0 1.1e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain IPK PF03770.11 OAP64910.1 - 1.1e-55 188.3 0.0 1.8e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 OAP64910.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Cu-oxidase_3 PF07732.10 OAP64912.1 - 9.6e-38 128.5 2.3 2.9e-37 126.9 1.6 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAP64912.1 - 3e-32 111.0 0.4 3e-32 111.0 0.3 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 OAP64912.1 - 8.3e-23 81.0 1.5 1.1e-22 80.6 0.2 1.9 2 0 0 2 2 2 1 Multicopper oxidase Pmp3 PF01679.12 OAP64914.1 - 2.9e-19 68.5 6.2 3.8e-19 68.1 4.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PEX11 PF05648.9 OAP64915.1 - 5.4e-08 32.3 0.1 4.3e-07 29.4 0.1 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Fungal_trans PF04082.13 OAP64916.1 - 2.4e-21 75.8 0.2 6.5e-21 74.3 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 OAP64917.1 - 4.6e-16 58.7 0.0 6.7e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP64917.1 - 2e-10 41.0 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP64917.1 - 9.6e-05 21.9 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 OAP64917.1 - 0.0038 17.5 0.0 0.0072 16.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 OAP64917.1 - 0.03 13.0 0.0 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAP64917.1 - 0.17 10.7 0.1 0.5 9.2 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Amidohydro_1 PF01979.15 OAP64918.1 - 2e-21 77.0 0.3 9.8e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAP64918.1 - 3.7e-14 52.3 0.0 9.7e-14 50.9 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP64918.1 - 1.5e-09 37.5 1.4 2.9e-05 23.4 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 OAP64918.1 - 2.4e-09 37.6 1.1 3.3e-08 33.9 0.8 2.4 1 1 0 1 1 1 1 Amidohydrolase Glutaminase PF04960.10 OAP64919.1 - 9.9e-100 333.2 1.2 1.2e-99 332.8 0.9 1.1 1 0 0 1 1 1 1 Glutaminase STAS PF01740.16 OAP64919.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 STAS domain PIR PF00399.14 OAP64920.1 - 1e-07 31.0 16.4 0.00048 19.3 2.7 2.9 2 0 0 2 2 2 2 Yeast PIR protein repeat LRR_4 PF12799.2 OAP64921.1 - 1e-37 127.1 29.1 9.1e-09 34.7 1.2 8.8 4 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAP64921.1 - 1.3e-28 98.5 29.3 3.4e-08 33.1 3.7 6.4 5 1 1 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 OAP64921.1 - 7e-17 58.8 27.8 0.17 12.0 0.1 12.6 11 2 1 12 12 12 6 Leucine Rich Repeat LRR_6 PF13516.1 OAP64921.1 - 1.1e-12 46.6 29.6 0.02 14.9 0.1 11.3 10 2 2 12 12 12 5 Leucine Rich repeat LRR_7 PF13504.1 OAP64921.1 - 7.2e-12 43.4 25.4 0.74 10.2 0.1 11.8 11 1 1 12 12 12 5 Leucine rich repeat LRR_9 PF14580.1 OAP64921.1 - 6.7e-06 25.7 10.4 0.28 10.7 0.7 4.6 2 1 2 4 4 4 3 Leucine-rich repeat Mito_carr PF00153.22 OAP64922.1 - 6.6e-50 166.7 0.6 1.8e-20 72.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 OAP64923.1 - 2.9e-79 266.8 0.3 3.4e-78 263.3 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 OAP64923.1 - 4.9e-28 95.9 17.5 8.9e-09 34.8 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAP64923.1 - 0.00083 18.2 0.2 1.1 7.9 0.1 2.4 1 1 0 2 2 2 2 Nup133 N terminal like Pkinase PF00069.20 OAP64924.1 - 1.3e-59 201.4 0.0 2e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP64924.1 - 9.2e-23 80.6 0.0 1.9e-22 79.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP64924.1 - 0.007 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAP64924.1 - 0.011 15.4 0.1 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 OAP64925.1 - 3.5e-26 90.4 0.1 5.5e-26 89.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 OAP64925.1 - 2.5e-24 85.2 0.3 4.4e-24 84.3 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 OAP64926.1 - 1.1e-112 376.2 0.0 1.2e-112 376.0 0.0 1.0 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 OAP64926.1 - 0.00041 19.7 0.0 0.00058 19.2 0.0 1.2 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) ADH_zinc_N PF00107.21 OAP64927.1 - 8.1e-31 106.2 0.0 1.2e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP64927.1 - 3.4e-18 66.7 0.0 6.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP64927.1 - 8.8e-08 31.8 0.0 9.7e-07 28.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain YgaB PF14182.1 OAP64928.1 - 0.15 12.2 1.5 28 5.0 0.1 3.2 3 1 1 4 4 4 0 YgaB-like protein HTH_Tnp_Tc3_1 PF11427.3 OAP64928.1 - 1.2 8.7 4.2 0.72 9.5 0.5 2.1 1 1 1 2 2 2 0 Tc3 transposase ATP-synt_C PF00137.16 OAP64929.1 - 1e-25 89.3 21.7 1.6e-17 63.1 3.8 2.6 3 0 0 3 3 3 2 ATP synthase subunit C Cation_efflux PF01545.16 OAP64929.1 - 4.4 6.3 12.8 0.062 12.3 0.6 2.4 1 1 0 2 2 2 0 Cation efflux family DDHD PF02862.12 OAP64930.1 - 2.6e-37 128.8 5.0 4.5e-36 124.7 0.0 3.3 2 2 0 2 2 2 1 DDHD domain Abhydrolase_5 PF12695.2 OAP64930.1 - 0.003 17.3 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP64930.1 - 0.0065 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1509 PF07420.6 OAP64930.1 - 0.038 13.2 13.2 0.077 12.2 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF2305 PF10230.4 OAP64930.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) MoCF_biosynth PF00994.19 OAP64931.1 - 1e-47 161.1 0.1 1.5e-23 82.7 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 OAP64931.1 - 1.2e-31 109.2 2.5 1.7e-31 108.7 1.8 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 OAP64931.1 - 6.9e-16 57.9 0.1 1.7e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) GAD-like PF08887.6 OAP64931.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 GAD-like domain Tannase PF07519.6 OAP64932.1 - 1.7e-98 330.3 0.0 3e-98 329.5 0.0 1.3 2 0 0 2 2 2 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 OAP64932.1 - 0.00014 21.8 0.0 0.00038 20.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP64932.1 - 0.014 15.1 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP64932.1 - 0.018 14.2 0.0 5.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAP64932.1 - 0.062 12.8 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold RNA_pol PF00940.14 OAP64933.1 - 3.4e-162 539.5 0.0 5.9e-162 538.7 0.0 1.4 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 OAP64933.1 - 5.7e-71 239.3 0.6 1.2e-70 238.3 0.0 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal GFO_IDH_MocA PF01408.17 OAP64934.1 - 2.3e-20 73.2 0.1 5e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 OAP64934.1 - 0.0031 17.8 0.1 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Sin_N PF04801.8 OAP64935.1 - 2.9e-22 79.1 0.0 6.4e-22 77.9 0.0 1.5 1 1 0 1 1 1 1 Sin-like protein conserved region AT_hook PF02178.14 OAP64935.1 - 0.3 10.9 8.4 1.3 8.9 5.8 2.2 1 0 0 1 1 1 0 AT hook motif NIR_SIR PF01077.17 OAP64936.1 - 1.2e-47 161.1 0.0 2.3e-42 144.0 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 OAP64936.1 - 3.8e-31 106.5 0.0 1.7e-14 53.1 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 OAP64936.1 - 9.5e-29 100.2 0.0 1.9e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 OAP64936.1 - 2e-07 30.7 0.6 5.4e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Methyltransf_11 PF08241.7 OAP64937.1 - 1e-17 64.3 0.1 1.4e-16 60.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP64937.1 - 2.6e-17 63.0 0.0 3.8e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAP64937.1 - 1.6e-16 60.2 0.0 5.4e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 OAP64937.1 - 2.6e-13 50.2 0.0 2.5e-12 47.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP64937.1 - 2.6e-13 49.8 0.0 9.6e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 OAP64937.1 - 1.2e-10 41.6 0.1 8.2e-10 38.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP64937.1 - 4.1e-10 40.2 0.0 8.3e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP64937.1 - 8.8e-09 35.4 0.0 1.9e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP64937.1 - 1.5e-06 27.5 0.0 7.5e-05 21.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAP64937.1 - 6.2e-05 22.4 0.0 0.00046 19.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 OAP64937.1 - 0.00022 20.6 0.0 0.0079 15.5 0.0 2.4 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW DOT1 PF08123.8 OAP64937.1 - 0.0018 17.6 0.0 0.0035 16.6 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_PK PF05891.7 OAP64937.1 - 0.0061 15.8 0.0 0.98 8.6 0.0 2.2 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.15 OAP64937.1 - 0.0089 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 OAP64937.1 - 0.051 13.1 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 OAP64937.1 - 0.057 13.0 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 OAP64937.1 - 0.084 12.4 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ADH_zinc_N PF00107.21 OAP64937.1 - 0.095 12.2 0.0 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Caleosin PF05042.8 OAP64938.1 - 1.1e-43 148.8 0.0 1.3e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 OAP64938.1 - 0.034 14.0 0.2 5.5 7.1 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain p450 PF00067.17 OAP64939.1 - 9.3e-45 153.0 0.0 1.2e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 OAP64939.1 - 0.048 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Reticulon Methyltransf_23 PF13489.1 OAP64940.1 - 3.3e-11 43.1 0.0 2e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP64940.1 - 0.0027 17.2 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP64940.1 - 0.012 16.1 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 OAP64940.1 - 0.015 15.7 0.0 0.043 14.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAP64940.1 - 0.021 15.2 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RicinB_lectin_2 PF14200.1 OAP64940.1 - 0.043 14.2 0.0 0.043 14.2 0.0 2.3 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Nitroreductase PF00881.19 OAP64941.1 - 1.2e-11 44.7 0.1 2.1e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Nitroreductase family FAD_binding_3 PF01494.14 OAP64943.1 - 1.2e-19 70.6 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP64943.1 - 2.8e-13 49.5 2.8 2.9e-06 26.4 1.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP64943.1 - 5.6e-07 29.4 0.6 1.3e-06 28.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP64943.1 - 9.3e-05 22.3 1.7 0.00091 19.1 1.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 OAP64943.1 - 0.00012 21.0 0.0 0.00035 19.4 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase GIDA PF01134.17 OAP64943.1 - 0.00016 20.6 3.1 0.00061 18.7 1.3 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 OAP64943.1 - 0.00022 19.9 0.9 0.15 10.6 0.4 2.3 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 OAP64943.1 - 0.00041 19.3 1.9 0.00041 19.3 1.3 1.6 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 OAP64943.1 - 0.00059 19.0 0.9 0.15 11.1 0.2 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 OAP64943.1 - 0.00066 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAP64943.1 - 0.0015 17.7 1.7 0.0023 17.1 1.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP64943.1 - 0.0023 16.4 2.4 0.0032 15.9 0.5 1.8 2 0 0 2 2 2 1 HI0933-like protein Rossmann-like PF10727.4 OAP64943.1 - 0.013 15.2 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_9 PF13454.1 OAP64943.1 - 0.019 14.7 1.0 0.71 9.6 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 OAP64943.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 OAP64943.1 - 0.042 13.5 0.3 0.073 12.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 OAP64943.1 - 0.045 12.8 0.1 0.088 11.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 OAP64943.1 - 0.054 13.9 1.0 0.14 12.5 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAP64943.1 - 0.076 12.7 0.3 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 OAP64943.1 - 0.086 12.2 0.4 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 OAP64943.1 - 0.18 10.6 1.4 1.1 8.1 1.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein ABC2_membrane PF01061.19 OAP64944.1 - 3.4e-82 274.6 73.9 5e-44 149.9 18.6 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 OAP64944.1 - 2.3e-37 128.3 0.0 2.1e-18 66.9 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 OAP64944.1 - 3.4e-31 106.9 13.2 1e-27 95.7 0.0 3.9 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 OAP64944.1 - 1.6e-15 56.9 0.1 4e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 OAP64944.1 - 3.3e-08 33.1 0.1 4.2e-05 23.0 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAP64944.1 - 1.5e-05 25.8 0.0 0.00091 20.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAP64944.1 - 2.9e-05 23.4 1.1 0.00061 19.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAP64944.1 - 4.7e-05 22.6 0.1 0.00068 18.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 OAP64944.1 - 5e-05 23.1 1.3 0.018 14.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 OAP64944.1 - 0.00015 21.2 0.6 0.0023 17.4 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 OAP64944.1 - 0.00018 21.5 0.4 0.0031 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 OAP64944.1 - 0.0013 18.0 0.1 0.02 14.1 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 OAP64944.1 - 0.0014 18.3 1.4 0.8 9.3 0.1 3.0 3 0 0 3 3 3 1 NACHT domain AAA_21 PF13304.1 OAP64944.1 - 0.0015 18.5 0.3 0.1 12.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 OAP64944.1 - 0.0023 18.2 0.1 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP64944.1 - 0.0035 17.4 0.8 0.1 12.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 OAP64944.1 - 0.0046 17.4 0.1 0.93 10.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 OAP64944.1 - 0.0047 16.9 0.3 0.013 15.5 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 OAP64944.1 - 0.0097 16.2 0.1 0.062 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 OAP64944.1 - 0.0097 14.9 58.3 0.0048 15.9 10.5 3.7 3 1 0 3 3 3 2 ABC-2 family transporter protein FtsK_SpoIIIE PF01580.13 OAP64944.1 - 0.037 13.5 0.1 4.6 6.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 OAP64944.1 - 0.037 14.1 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 OAP64944.1 - 0.037 14.2 0.1 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 OAP64944.1 - 0.046 13.3 1.2 0.33 10.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 OAP64944.1 - 0.061 13.2 0.0 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 OAP64944.1 - 0.062 12.1 0.5 2.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 OAP64944.1 - 0.072 12.5 0.6 13 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain Pax2_C PF12403.3 OAP64944.1 - 0.14 11.8 3.7 0.2 11.3 0.2 2.4 2 0 0 2 2 2 0 Paired-box protein 2 C terminal ArgK PF03308.11 OAP64944.1 - 0.27 9.9 0.1 21 3.7 0.1 2.2 2 0 0 2 2 2 0 ArgK protein AAA_15 PF13175.1 OAP64944.1 - 0.31 10.0 0.0 0.58 9.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Clp1 PF06807.9 OAP64945.1 - 8.3e-17 61.5 0.0 4.4e-16 59.2 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 OAP64945.1 - 4e-07 29.8 0.0 7.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 OAP64945.1 - 0.0012 18.4 0.0 0.0035 16.9 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 OAP64945.1 - 0.021 14.7 0.0 0.087 12.7 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 OAP64945.1 - 0.043 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.5 OAP64945.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.1 OAP64945.1 - 0.22 10.1 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain IPK PF03770.11 OAP64946.1 - 2.1e-53 180.9 0.0 8.5e-53 178.9 0.0 1.9 1 1 0 1 1 1 1 Inositol polyphosphate kinase DUF2457 PF10446.4 OAP64946.1 - 0.047 12.4 5.4 0.064 11.9 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 OAP64946.1 - 1.1 9.5 6.9 3.1 8.1 4.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 OAP64946.1 - 3.4 5.5 6.2 4.8 5.0 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.1 OAP64946.1 - 8.1 6.6 11.0 24 5.1 7.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Arb1 PF09692.5 OAP64947.1 - 4.8e-99 331.8 0.0 6e-99 331.5 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Fmp27 PF10344.4 OAP64948.1 - 1.5e-185 618.5 0.0 3.2e-185 617.4 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 OAP64948.1 - 4.5e-164 546.6 3.4 4.5e-164 546.6 2.4 1.9 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 OAP64948.1 - 2.8e-150 500.8 0.2 2.8e-150 500.8 0.1 2.9 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 OAP64948.1 - 1.8e-56 190.2 0.7 6.3e-56 188.4 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 OAP64948.1 - 2e-50 170.7 0.0 5.5e-50 169.3 0.0 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 OAP64948.1 - 2.3e-32 111.4 0.0 5.5e-31 107.0 0.0 3.4 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain ACT_7 PF13840.1 OAP64949.1 - 0.17 11.4 0.3 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 ACT domain RRM_6 PF14259.1 OAP64950.1 - 1.3e-12 47.4 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAP64950.1 - 5.7e-12 45.1 0.0 1.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP64950.1 - 5.4e-05 22.9 0.0 8.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) B-block_TFIIIC PF04182.7 OAP64951.1 - 4.6e-19 68.0 0.0 4.3e-17 61.7 0.0 3.0 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 OAP64951.1 - 4.4e-05 23.0 2.6 0.064 12.9 0.0 4.0 4 0 0 4 4 4 2 MarR family MarR PF01047.17 OAP64951.1 - 0.00048 19.7 0.4 1.1 9.0 0.1 2.9 2 0 0 2 2 2 2 MarR family Fe_dep_repress PF01325.14 OAP64951.1 - 0.059 13.3 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.1 OAP64951.1 - 0.081 12.3 2.4 0.19 11.1 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding MMS1_N PF10433.4 OAP64952.1 - 9.4e-74 248.3 0.0 1.2e-72 244.6 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 OAP64952.1 - 2.3e-52 178.0 0.0 7.9e-52 176.3 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region Pyrophosphatase PF00719.14 OAP64952.1 - 0.084 12.3 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Inorganic pyrophosphatase PQQ_3 PF13570.1 OAP64952.1 - 0.5 10.7 2.2 17 5.8 0.1 4.1 5 0 0 5 5 5 0 PQQ-like domain Ferric_reduct PF01794.14 OAP64954.1 - 1.4e-17 63.9 9.2 1.4e-17 63.9 6.4 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 OAP64954.1 - 0.00071 19.4 0.0 0.0046 16.8 0.0 2.2 3 0 0 3 3 3 1 FAD-binding domain NAD_binding_1 PF00175.16 OAP64954.1 - 0.0014 19.1 0.0 0.0094 16.5 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 OAP64954.1 - 0.0021 17.9 0.8 1.7 8.5 0.3 2.7 2 1 1 3 3 3 2 Ferric reductase NAD binding domain WD40 PF00400.27 OAP64957.1 - 5.3e-39 130.7 10.2 2.6e-10 39.7 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 OAP64957.1 - 6.5e-08 31.1 13.7 0.019 13.1 0.5 4.8 2 2 3 5 5 5 3 Nucleoporin Nup120/160 APG6 PF04111.7 OAP64957.1 - 0.00033 19.8 5.6 0.00052 19.1 3.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Uds1 PF15456.1 OAP64957.1 - 0.014 15.3 3.0 0.014 15.3 2.1 1.8 2 0 0 2 2 2 0 Up-regulated During Septation PQQ_2 PF13360.1 OAP64957.1 - 0.016 14.6 0.4 0.069 12.6 0.0 2.1 2 1 0 2 2 2 0 PQQ-like domain IncA PF04156.9 OAP64957.1 - 0.042 13.4 5.2 0.068 12.7 3.6 1.3 1 0 0 1 1 1 0 IncA protein HAUS-augmin3 PF14932.1 OAP64957.1 - 0.079 12.1 4.7 0.14 11.3 3.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Cortex-I_coil PF09304.5 OAP64957.1 - 0.17 11.8 8.9 1.4 8.9 0.4 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF342 PF03961.8 OAP64957.1 - 1 7.6 4.7 1.5 7.1 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CM_2 PF01817.16 OAP64958.1 - 5.4e-10 39.2 0.2 3.1e-05 23.9 0.0 3.4 2 2 0 2 2 2 2 Chorismate mutase type II TUG-UBL1 PF11470.3 OAP64958.1 - 0.077 12.9 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 GLUT4 regulating protein TUG BCIP PF13862.1 OAP64959.1 - 1.6e-72 243.0 0.0 2.2e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Nuc_N PF14448.1 OAP64959.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Nuclease N terminal GATase PF00117.23 OAP64960.1 - 8.6e-40 136.2 0.0 1.5e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 OAP64960.1 - 3.5e-36 122.8 0.0 7.7e-36 121.7 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 OAP64960.1 - 2.2e-11 43.1 0.1 6.1e-07 28.5 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 OAP64960.1 - 4.2e-09 36.1 0.0 8.5e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Asn_synthase PF00733.16 OAP64960.1 - 0.0025 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 OAP64960.1 - 0.003 16.8 0.0 0.016 14.5 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 OAP64960.1 - 0.0035 15.9 0.1 0.0085 14.6 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 OAP64960.1 - 0.011 15.1 0.0 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 OAP64960.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 OAP64960.1 - 0.08 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 OAP64960.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 PP-loop family TauD PF02668.11 OAP64961.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2183 PF09949.4 OAP64963.1 - 1.6e-33 114.5 0.0 3.6e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 OAP64963.1 - 0.00034 20.6 0.1 0.0033 17.4 0.0 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain LNS2 PF08235.8 OAP64963.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Herpes_UL32 PF06070.6 OAP64964.1 - 0.12 10.7 5.8 0.13 10.7 4.0 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF566 PF04484.7 OAP64964.1 - 0.17 11.3 5.4 0.21 11.0 3.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) SNAP-25 PF00835.14 OAP64964.1 - 0.96 10.2 5.7 0.33 11.7 0.8 2.3 1 1 2 3 3 3 0 SNAP-25 family WD40 PF00400.27 OAP64966.1 - 5.5e-07 29.2 8.9 0.0074 16.1 0.2 6.5 8 0 0 8 8 8 3 WD domain, G-beta repeat TFIIIC_delta PF12657.2 OAP64966.1 - 0.01 15.5 0.1 0.038 13.6 0.0 1.9 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term TPR_11 PF13414.1 OAP64968.1 - 1.4e-12 47.0 0.5 4.3e-12 45.5 0.3 1.8 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 OAP64968.1 - 5.6e-10 38.4 0.6 0.0015 18.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAP64968.1 - 3.1e-07 29.7 0.3 0.022 14.6 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAP64968.1 - 3.8e-07 29.4 0.6 0.049 13.4 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAP64968.1 - 4e-07 29.8 0.8 9.1e-07 28.7 0.6 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 OAP64968.1 - 0.00024 21.2 0.3 0.00046 20.2 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 OAP64968.1 - 0.00031 20.9 0.2 0.00076 19.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAP64968.1 - 0.00052 20.4 0.2 0.16 12.6 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAP64968.1 - 0.00094 19.7 0.2 0.002 18.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Cluap1 PF10234.4 OAP64968.1 - 0.021 14.0 0.1 0.042 13.0 0.1 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 MIT PF04212.13 OAP64968.1 - 0.047 13.5 0.2 0.2 11.5 0.1 2.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 OAP64968.1 - 0.066 13.6 0.2 4.9 7.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP-synt_DE PF00401.15 OAP64968.1 - 2 8.3 5.4 4 7.3 0.9 2.6 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain HAD_2 PF13419.1 OAP64969.1 - 1.1e-12 48.5 0.0 3.7e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAP64969.1 - 7.8e-06 26.4 0.0 0.00047 20.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAP64969.1 - 3.2e-05 23.5 0.0 9.4e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 HAD-hyrolase-like PQ-loop PF04193.9 OAP64970.1 - 3.2e-23 81.0 14.1 7.8e-12 44.5 2.0 2.9 2 1 0 2 2 2 2 PQ loop repeat DUF588 PF04535.7 OAP64970.1 - 0.028 13.9 1.2 0.24 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF588) DUF4381 PF14316.1 OAP64970.1 - 0.089 12.9 0.8 25 4.9 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Mtp PF03821.11 OAP64970.1 - 0.58 9.4 4.0 0.38 10.0 0.2 2.3 3 0 0 3 3 3 0 Golgi 4-transmembrane spanning transporter Fungal_trans_2 PF11951.3 OAP64971.1 - 2e-12 46.4 0.1 9.9e-12 44.1 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP64972.1 - 8.6e-10 38.3 10.3 1.4e-09 37.6 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxysterol_BP PF01237.13 OAP64975.1 - 3.9e-68 229.5 0.0 6.5e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein FAD_binding_4 PF01565.18 OAP64977.1 - 1.6e-15 56.7 0.0 3.3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Aldedh PF00171.17 OAP64978.1 - 2.3e-150 501.0 0.1 2.8e-150 500.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP64978.1 - 0.03 13.0 0.2 0.049 12.3 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) SnoaL_2 PF12680.2 OAP64979.1 - 4.8e-07 30.1 0.1 8.8e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 OAP64979.1 - 0.031 14.1 0.1 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.11 OAP64980.1 - 1e-33 116.5 40.1 1e-33 116.5 27.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Tropomyosin_1 PF12718.2 OAP64981.1 - 0.0059 16.4 5.8 0.0081 16.0 4.0 1.2 1 0 0 1 1 1 1 Tropomyosin like FliJ PF02050.11 OAP64981.1 - 0.012 15.6 3.8 0.032 14.2 2.7 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein DUF2205 PF10224.4 OAP64981.1 - 0.062 12.8 1.4 0.063 12.8 0.0 1.7 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) bZIP_2 PF07716.10 OAP64981.1 - 0.13 12.1 4.0 0.24 11.2 0.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper V_ATPase_I PF01496.14 OAP64981.1 - 0.28 8.9 1.6 0.3 8.9 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.7 OAP64981.1 - 0.49 10.5 3.3 0.59 10.3 1.7 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) IncA PF04156.9 OAP64981.1 - 0.6 9.6 3.6 0.79 9.2 2.5 1.2 1 0 0 1 1 1 0 IncA protein Syntaxin PF00804.20 OAP64981.1 - 1.3 9.2 5.8 1.9 8.7 4.0 1.4 1 1 0 1 1 1 0 Syntaxin PI3Ka PF00613.15 OAP64982.1 - 4.9e-50 169.2 0.2 8.4e-50 168.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 OAP64982.1 - 1.1e-44 152.6 0.0 4.8e-43 147.3 0.0 3.1 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 OAP64982.1 - 4.9e-25 87.9 0.0 1.1e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 OAP64983.1 - 2.4e-32 110.7 0.0 5.4e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 OAP64983.1 - 4.5e-13 48.8 0.0 1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1470 PF07336.6 OAP64983.1 - 1.5 9.1 6.0 0.45 10.8 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1470) MFS_1 PF07690.11 OAP64984.1 - 5.3e-31 107.6 25.3 7.6e-31 107.0 17.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 OAP64985.1 - 1.9e-34 119.3 0.3 2.6e-34 118.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 OAP64985.1 - 1.3e-32 112.0 0.2 2.8e-32 111.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 OAP64985.1 - 2.9e-14 53.2 0.1 2.9e-14 53.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP64985.1 - 0.02 13.7 1.7 0.056 12.3 0.5 2.2 4 1 0 4 4 4 0 Glucose inhibited division protein A DAO PF01266.19 OAP64985.1 - 0.087 11.7 1.0 0.18 10.6 0.7 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.1 OAP64985.1 - 0.091 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ECH PF00378.15 OAP64986.1 - 4.3e-39 134.0 0.0 7.2e-39 133.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Herpes_pp38 PF04846.8 OAP64986.1 - 0.12 11.7 0.4 0.3 10.3 0.0 1.9 2 1 0 2 2 2 0 Herpesvirus pp38 phosphoprotein Ribosomal_L7Ae PF01248.21 OAP64988.1 - 2.6e-27 94.1 0.1 3.3e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 OAP64988.1 - 0.048 13.4 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain ATP-synt_C PF00137.16 OAP64989.1 - 3.3e-32 110.2 28.4 1e-18 66.9 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 OAP64989.1 - 0.039 13.0 1.4 2.9 6.9 0.1 2.1 1 1 1 2 2 2 0 Abscisic acid G-protein coupled receptor Flavi_NS4A PF01350.12 OAP64989.1 - 0.22 11.0 3.3 0.11 12.0 0.5 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2970 PF11174.3 OAP64989.1 - 4.5 6.9 9.8 0.61 9.7 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF1713 PF08213.6 OAP64990.1 - 1e-14 53.7 17.6 2.2e-14 52.7 12.2 1.6 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Dabb PF07876.7 OAP64991.1 - 1.1e-10 41.7 0.1 1.2e-10 41.6 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ank_2 PF12796.2 OAP64992.1 - 2.4e-10 40.5 0.0 0.00051 20.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP64992.1 - 8.5e-09 35.6 1.9 0.019 15.4 0.0 4.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 OAP64992.1 - 1.1e-06 28.1 1.3 0.016 15.0 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 OAP64992.1 - 0.00058 19.8 0.1 0.1 12.8 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 OAP64992.1 - 0.00072 19.7 0.4 1.6 9.0 0.0 4.5 3 2 1 4 4 4 1 Ankyrin repeats (many copies) ThiF PF00899.16 OAP64993.1 - 3e-35 120.9 0.2 5.9e-35 120.0 0.1 1.5 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 OAP64993.1 - 0.0013 18.9 0.1 0.003 17.8 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 OAP64993.1 - 0.015 15.2 1.4 0.062 13.2 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 OAP64993.1 - 0.017 14.5 0.1 0.053 12.8 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rib_5-P_isom_A PF06026.9 OAP64993.1 - 0.023 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Saccharop_dh PF03435.13 OAP64993.1 - 0.024 13.6 0.6 1 8.2 0.2 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 OAP64993.1 - 0.13 11.9 0.9 0.97 9.0 0.6 2.2 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAP64993.1 - 0.14 12.2 1.0 0.78 9.8 0.1 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_17 PF00332.13 OAP64993.1 - 0.22 10.5 0.0 0.6 9.0 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 Isy1 PF06246.7 OAP64994.1 - 2.7e-83 279.2 0.2 3.5e-83 278.9 0.1 1.1 1 0 0 1 1 1 1 Isy1-like splicing family DUF904 PF06005.7 OAP64994.1 - 0.13 12.5 1.5 0.29 11.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) CAP59_mtransfer PF11735.3 OAP64996.1 - 9.4e-78 260.7 0.0 1.3e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MaoC_dehydratas PF01575.14 OAP64997.1 - 2.9e-05 23.4 0.0 5.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain CENP-T PF15511.1 OAP64998.1 - 1.7e-53 182.3 30.1 2.1e-53 182.0 20.9 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 OAP64998.1 - 1.3e-09 38.1 0.1 2.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 OAP64998.1 - 5.4e-06 26.4 0.1 9.8e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 OAP64998.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated SURF1 PF02104.10 OAP64999.1 - 3.8e-64 216.4 0.0 4.7e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 OAP65000.1 - 2e-07 30.9 0.0 7.1e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.1 OAP65000.1 - 0.042 13.8 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like IncA PF04156.9 OAP65000.1 - 0.2 11.2 2.3 1 8.9 0.0 2.3 2 0 0 2 2 2 0 IncA protein Elongin_A PF06881.6 OAP65000.1 - 0.29 11.5 4.7 0.84 10.0 3.3 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A EBV-NA3 PF05009.7 OAP65001.1 - 0.0091 15.2 0.2 0.014 14.6 0.2 1.2 1 0 0 1 1 1 1 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Ribosomal_60s PF00428.14 OAP65001.1 - 0.037 14.4 0.1 0.037 14.4 0.1 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Amidohydro_2 PF04909.9 OAP65002.1 - 4.1e-16 59.3 1.1 7.4e-16 58.5 0.8 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 OAP65002.1 - 0.027 14.4 0.2 0.086 12.8 0.0 1.8 2 1 0 2 2 2 0 Amidohydrolase adh_short PF00106.20 OAP65003.1 - 1e-22 80.8 0.9 4.8e-21 75.4 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65003.1 - 6.3e-20 71.9 0.0 7.5e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65003.1 - 1.3e-08 34.7 0.1 5.8e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.13 OAP65005.1 - 2.1e-21 75.9 0.0 3.1e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP65005.1 - 3.6e-08 33.1 11.8 6.8e-08 32.2 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 OAP65006.1 - 2.1e-20 72.7 0.0 3.4e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 OAP65006.1 - 1.4e-10 41.5 0.0 2.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 OAP65006.1 - 1.3e-09 38.0 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Pyr_redox_3 PF13738.1 OAP65007.1 - 3.6e-26 92.5 0.1 6.6e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP65007.1 - 6.2e-14 51.0 0.0 1.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 OAP65007.1 - 1.5e-10 40.4 0.0 2.4e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP65007.1 - 1.2e-08 35.0 0.0 2.4e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP65007.1 - 9.2e-05 22.4 0.0 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAP65007.1 - 0.00047 19.3 0.7 0.0058 15.7 0.4 2.1 1 1 1 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 OAP65007.1 - 0.00064 19.3 0.3 0.0018 17.8 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 OAP65007.1 - 0.0014 17.1 0.2 0.025 13.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 OAP65007.1 - 0.0043 16.0 0.9 0.025 13.4 0.2 2.4 1 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAP65007.1 - 0.0067 15.3 0.5 0.03 13.1 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 OAP65007.1 - 0.0084 15.0 0.0 0.027 13.4 0.0 1.8 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.15 OAP65007.1 - 0.0088 16.1 0.0 0.69 10.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 OAP65007.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family LAM_C PF12544.3 OAP65007.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Pyr_redox_2 PF07992.9 OAP65008.1 - 6.5e-28 97.9 0.0 1.2e-27 97.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 OAP65008.1 - 1.8e-25 89.1 0.2 7.1e-25 87.1 0.0 2.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 OAP65008.1 - 1.5e-20 73.3 2.7 4.3e-19 68.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAP65008.1 - 2.5e-08 33.1 0.2 0.0012 17.8 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A 3HCDH_N PF02737.13 OAP65008.1 - 4.6e-05 23.1 1.8 0.0042 16.7 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 OAP65008.1 - 0.00039 19.5 0.2 0.16 10.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain ApbA PF02558.11 OAP65008.1 - 0.00074 18.9 0.7 0.0099 15.3 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 OAP65008.1 - 0.00096 19.1 4.0 0.091 12.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 OAP65008.1 - 0.0025 16.9 0.0 0.006 15.7 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 OAP65008.1 - 0.003 17.8 0.5 0.034 14.4 0.0 2.7 2 1 0 2 2 2 1 XdhC Rossmann domain Pyr_redox_3 PF13738.1 OAP65008.1 - 0.0038 17.3 0.2 0.11 12.4 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 OAP65008.1 - 0.0048 16.7 0.6 0.36 10.6 0.0 2.7 2 0 0 2 2 2 1 ThiF family DAO PF01266.19 OAP65008.1 - 0.0048 15.8 7.9 0.31 9.8 0.0 3.3 3 1 0 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 OAP65008.1 - 0.0071 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 OAP65008.1 - 0.0094 14.9 0.2 0.43 9.4 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 OAP65008.1 - 0.014 14.3 1.9 0.87 8.4 0.0 3.1 2 1 1 3 3 3 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 OAP65008.1 - 0.027 14.2 0.9 0.41 10.3 0.0 2.4 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 OAP65008.1 - 0.052 12.6 6.0 1.3 8.0 1.7 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAP65008.1 - 0.056 13.7 0.2 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 OAP65008.1 - 0.099 11.0 4.9 0.93 7.8 0.1 3.0 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 OAP65008.1 - 0.11 11.3 7.7 0.025 13.4 1.1 2.4 3 0 0 3 3 3 0 FAD binding domain An_peroxidase PF03098.10 OAP65009.1 - 8.5e-98 328.0 0.0 3e-95 319.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 OAP65009.1 - 7.7e-08 31.2 0.0 1.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L14 PF00238.14 OAP65010.1 - 2.4e-33 114.4 0.0 2.7e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Fungal_trans_2 PF11951.3 OAP65011.1 - 9e-07 27.8 4.0 9e-07 27.8 2.8 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.16 OAP65012.1 - 2.2e-65 219.8 0.0 3e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 zf-C2H2_4 PF13894.1 OAP65014.1 - 0.0016 18.6 1.6 0.064 13.6 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 OAP65014.1 - 0.0016 18.6 2.9 0.034 14.5 0.1 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 OAP65014.1 - 0.11 12.6 1.8 14 6.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HEAT_EZ PF13513.1 OAP65015.1 - 1e-30 105.4 4.4 4.7e-14 52.3 0.0 10.3 8 2 4 12 12 11 4 HEAT-like repeat HEAT PF02985.17 OAP65015.1 - 5.4e-25 85.1 15.1 3e-05 23.7 0.1 10.1 11 0 0 11 11 10 5 HEAT repeat HEAT_2 PF13646.1 OAP65015.1 - 4.8e-23 81.2 0.2 1.1e-06 28.8 0.0 6.6 4 2 1 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.2 OAP65015.1 - 7.2e-11 42.3 0.0 0.018 15.4 0.0 6.3 4 3 3 7 7 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 OAP65015.1 - 7.1e-07 28.2 4.7 0.19 10.4 0.0 4.9 4 2 0 5 5 5 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 OAP65015.1 - 2.4e-06 27.5 0.6 0.029 14.2 0.0 5.2 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 OAP65015.1 - 1.2e-05 25.0 1.7 0.057 13.3 0.1 5.1 4 1 1 5 5 5 1 Importin-beta N-terminal domain CLASP_N PF12348.3 OAP65015.1 - 3.3e-05 23.3 0.0 3.3 6.9 0.0 4.6 4 2 0 5 5 5 2 CLASP N terminal RIX1 PF08167.7 OAP65015.1 - 0.00011 21.9 2.1 3.3 7.3 0.0 4.6 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 OAP65015.1 - 0.00011 20.6 0.1 0.056 11.7 0.0 3.1 2 1 0 2 2 2 2 Adaptin N terminal region Arm PF00514.18 OAP65015.1 - 0.0013 18.5 1.1 0.37 10.6 0.0 4.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 OAP65015.1 - 0.0014 18.9 3.1 3.1 8.5 0.0 6.0 7 0 0 7 7 6 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 OAP65015.1 - 0.063 11.5 0.1 0.24 9.6 0.0 2.0 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Syja_N PF02383.13 OAP65016.1 - 1.5e-92 309.7 0.0 2.4e-92 309.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 OAP65016.1 - 4.2e-34 116.3 0.1 8.4e-34 115.4 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Pox_A11 PF05061.8 OAP65016.1 - 0.12 11.4 0.5 0.25 10.3 0.3 1.4 1 0 0 1 1 1 0 Poxvirus A11 Protein Pkinase PF00069.20 OAP65017.1 - 2.6e-47 161.1 0.0 7.3e-45 153.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAP65017.1 - 7.1e-29 100.6 0.0 6.2e-28 97.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP65017.1 - 0.00018 20.5 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 OAP65017.1 - 0.0032 16.3 0.1 0.0058 15.5 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 OAP65017.1 - 0.049 13.3 0.0 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAP65017.1 - 0.064 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sec_GG PF07549.9 OAP65017.1 - 0.11 11.8 0.2 0.34 10.2 0.2 1.9 1 0 0 1 1 1 0 SecD/SecF GG Motif Mem_trans PF03547.13 OAP65018.1 - 1.1e-54 185.2 0.1 5e-54 183.0 0.1 1.8 1 1 0 1 1 1 1 Membrane transport protein ADH_zinc_N_2 PF13602.1 OAP65019.1 - 2e-14 54.5 0.0 4.8e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAP65019.1 - 2.7e-05 23.7 0.0 7e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DXP_reductoisom PF02670.11 OAP65019.1 - 0.083 13.4 0.1 0.16 12.4 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Hist_deacetyl PF00850.14 OAP65020.1 - 3.7e-77 259.6 0.3 6.6e-77 258.8 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.16 OAP65021.1 - 3e-34 117.2 0.0 5.2e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 OAP65021.1 - 3.2e-23 82.0 0.4 6e-23 81.1 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 OAP65021.1 - 1.2e-08 34.4 0.0 2.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain NIF PF03031.13 OAP65023.1 - 1.1e-37 129.1 0.0 1.8e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UBA_2 PF08587.6 OAP65023.1 - 0.037 14.2 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) F-box-like PF12937.2 OAP65024.1 - 0.0024 17.5 0.2 0.0051 16.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like 2-Hacid_dh_C PF02826.14 OAP65025.1 - 8.2e-42 142.3 0.0 1.1e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP65025.1 - 9e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 OAP65025.1 - 0.004 17.4 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.1 OAP65025.1 - 0.077 13.2 0.0 2.1 8.6 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding TrkH PF02386.11 OAP65026.1 - 2.6e-86 289.3 5.6 3e-81 272.7 0.8 2.1 2 0 0 2 2 2 2 Cation transport protein DUF2470 PF10615.4 OAP65027.1 - 5.5e-22 77.7 0.2 8.3e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF2339 PF10101.4 OAP65027.1 - 0.021 13.1 3.2 0.027 12.7 2.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF3000 PF11452.3 OAP65027.1 - 0.022 14.0 0.1 0.044 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3000) PH_10 PF15411.1 OAP65028.1 - 2.5e-35 121.1 0.0 4.5e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 OAP65028.1 - 1.2e-31 109.9 0.8 2e-31 109.2 0.6 1.3 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 OAP65028.1 - 1.1e-26 92.7 0.0 1.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 OAP65028.1 - 8.9e-08 31.6 0.0 2.9e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 OAP65028.1 - 0.0076 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Abhydrolase_3 PF07859.8 OAP65029.1 - 6.7e-50 169.5 0.0 9.6e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP65029.1 - 1.4e-06 27.3 0.0 2.9e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Utp11 PF03998.8 OAP65030.1 - 4.2e-53 180.6 14.0 7.3e-53 179.8 9.7 1.4 1 1 0 1 1 1 1 Utp11 protein eIF3_subunit PF08597.5 OAP65030.1 - 6.6e-05 22.5 9.6 6.6e-05 22.5 6.6 1.9 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit Cmc1 PF08583.5 OAP65031.1 - 4.3e-19 68.0 1.2 4.3e-19 68.0 0.8 2.2 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_S2 PF00318.15 OAP65031.1 - 0.17 11.0 0.4 0.21 10.7 0.3 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 eIF3_N PF09440.5 OAP65031.1 - 0.36 10.9 3.7 0.58 10.3 2.6 1.3 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF1682 PF07946.9 OAP65031.1 - 6.6 5.4 14.6 9.1 5.0 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DBINO PF13892.1 OAP65031.1 - 8.9 6.3 21.0 14 5.6 14.4 1.5 1 1 0 1 1 1 0 DNA-binding domain DUF940 PF06082.6 OAP65032.1 - 0.04 12.4 0.1 0.045 12.3 0.1 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Pox_I3 PF04661.7 OAP65032.1 - 0.14 10.8 1.0 0.19 10.4 0.7 1.1 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein Aminotran_3 PF00202.16 OAP65033.1 - 2.8e-49 167.7 0.0 5.1e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 OAP65033.1 - 0.034 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAP65033.1 - 0.037 13.1 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAP65034.1 - 7e-37 127.2 0.0 8e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SAGA-Tad1 PF12767.2 OAP65035.1 - 1.2 8.7 13.1 1.2 8.6 9.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RR_TM4-6 PF06459.7 OAP65035.1 - 3.1 7.6 8.1 4.2 7.1 5.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HET PF06985.6 OAP65038.1 - 3.4e-06 27.2 0.0 8.3e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TrmE_N PF10396.4 OAP65039.1 - 1.7e-21 76.3 0.0 6e-21 74.5 0.0 2.0 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 OAP65039.1 - 7e-19 68.0 0.1 7.5e-18 64.7 0.1 2.8 2 1 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 OAP65039.1 - 3.3e-18 65.7 0.0 5.4e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAP65039.1 - 6e-06 26.1 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 OAP65039.1 - 3e-05 23.5 0.1 0.013 14.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 OAP65039.1 - 7e-05 22.1 0.0 0.00022 20.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 OAP65039.1 - 0.0016 18.9 0.0 0.004 17.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 OAP65039.1 - 0.032 13.6 0.7 0.29 10.5 0.5 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 OAP65039.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter CAP PF00188.21 OAP65040.1 - 9.2e-17 61.6 0.3 1.4e-16 61.1 0.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CCDC14 PF15254.1 OAP65040.1 - 7.8 4.7 5.8 9.8 4.4 4.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 MFS_1 PF07690.11 OAP65041.1 - 9.7e-51 172.5 25.9 4.5e-45 153.9 9.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP65041.1 - 1.1e-10 40.6 11.6 1.1e-10 40.6 8.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter LNP1 PF15419.1 OAP65041.1 - 0.051 13.6 0.3 0.051 13.6 0.2 2.0 3 0 0 3 3 3 0 Leukemia NUP98 fusion partner 1 Stn1 PF10451.4 OAP65042.1 - 3.1e-11 42.6 0.4 7e-10 38.1 0.0 2.2 2 0 0 2 2 2 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 OAP65042.1 - 0.0024 17.6 0.0 0.015 15.1 0.0 2.0 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain TRAP-gamma PF07074.7 OAP65042.1 - 0.2 11.1 0.2 0.37 10.3 0.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) MIF4G PF02854.14 OAP65043.1 - 4.2e-51 173.3 0.0 6.5e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 OAP65043.1 - 5.1e-20 71.1 0.5 1.5e-19 69.6 0.3 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Borrelia_P83 PF05262.6 OAP65043.1 - 0.063 11.5 35.2 0.1 10.8 24.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DnaJ PF00226.26 OAP65044.1 - 1.5e-22 79.0 3.2 1.5e-22 79.0 2.2 2.2 2 0 0 2 2 2 1 DnaJ domain Collar PF07484.7 OAP65046.1 - 0.2 11.4 1.5 0.53 10.1 0.1 2.5 3 0 0 3 3 3 0 Phage Tail Collar Domain Usp PF00582.21 OAP65047.1 - 6.6e-16 58.7 7.5 2.8e-15 56.7 0.8 3.4 2 1 0 2 2 2 1 Universal stress protein family Ycf1 PF05758.7 OAP65047.1 - 0.062 11.0 1.4 0.091 10.4 1.0 1.2 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 OAP65047.1 - 0.31 10.0 0.4 0.6 9.0 0.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter dCMP_cyt_deam_1 PF00383.17 OAP65048.1 - 1e-12 47.5 0.0 1.6e-09 37.3 0.0 2.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 OAP65048.1 - 0.013 15.2 0.2 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase CDK2AP PF09806.4 OAP65048.1 - 0.63 10.2 7.4 1 9.5 5.2 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Actino_peptide PF14408.1 OAP65048.1 - 1.7 8.5 9.5 3.8 7.5 3.4 2.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes WD40 PF00400.27 OAP65049.1 - 3.4e-24 83.7 14.4 2.9e-05 23.7 0.0 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat bZIP_1 PF00170.16 OAP65051.1 - 5.2e-08 32.7 9.2 6.5e-08 32.4 4.5 2.1 1 1 1 2 2 2 1 bZIP transcription factor CENP-F_leu_zip PF10473.4 OAP65051.1 - 0.00054 19.8 3.0 0.00079 19.3 2.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 OAP65051.1 - 0.0015 18.2 2.4 0.0024 17.5 1.6 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 OAP65051.1 - 0.0097 15.7 7.7 0.0097 15.7 5.3 2.7 2 1 1 3 3 3 1 Basic region leucine zipper TMF_DNA_bd PF12329.3 OAP65051.1 - 0.057 13.2 1.9 0.1 12.4 1.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 OAP65051.1 - 0.072 12.1 2.5 0.098 11.6 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FlxA PF14282.1 OAP65051.1 - 0.075 12.9 1.4 0.63 10.0 1.0 2.2 1 1 0 1 1 1 0 FlxA-like protein Jnk-SapK_ap_N PF09744.4 OAP65051.1 - 0.12 12.3 4.7 0.19 11.7 3.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 IncA PF04156.9 OAP65051.1 - 0.13 11.8 5.8 0.18 11.3 4.0 1.1 1 0 0 1 1 1 0 IncA protein DUF2400 PF09674.5 OAP65051.1 - 0.13 11.9 1.1 0.21 11.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Mnd1 PF03962.10 OAP65051.1 - 0.14 11.7 3.6 0.19 11.3 2.5 1.2 1 0 0 1 1 1 0 Mnd1 family CorA PF01544.13 OAP65051.1 - 0.58 9.1 3.5 12 4.7 1.2 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein bZIP_Maf PF03131.12 OAP65051.1 - 1 9.6 14.3 0.058 13.6 6.0 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.10 OAP65051.1 - 1.2 8.6 3.7 2.2 7.8 0.7 2.1 1 1 1 2 2 2 0 Septum formation initiator G-alpha PF00503.15 OAP65052.1 - 3.1e-119 398.1 2.3 3.8e-119 397.8 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAP65052.1 - 1.6e-13 50.2 1.4 1.6e-08 34.0 0.0 3.1 3 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAP65052.1 - 0.019 14.1 4.8 1.4 7.9 0.1 2.9 2 2 1 3 3 3 0 Gtr1/RagA G protein conserved region Miro PF08477.8 OAP65052.1 - 0.027 14.9 1.1 0.96 9.9 0.3 3.1 2 2 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 OAP65052.1 - 0.027 14.4 0.1 4.9 7.1 0.0 2.7 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.1 OAP65052.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_capsid PF06112.6 OAP65053.1 - 0.0088 16.0 4.8 0.011 15.7 3.3 1.2 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein GSHPx PF00255.14 OAP65054.1 - 1.4e-35 120.8 0.1 1.8e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.1 OAP65054.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Thioredoxin_2 PF13098.1 OAP65054.1 - 0.048 13.8 0.0 0.071 13.3 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.16 OAP65054.1 - 0.095 12.3 0.1 0.17 11.5 0.1 1.7 1 1 0 1 1 1 0 AhpC/TSA family Sarcoglycan_2 PF05510.8 OAP65055.1 - 0.00063 18.1 0.0 0.00064 18.1 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon TMEM154 PF15102.1 OAP65055.1 - 0.00068 19.3 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family SIT PF15330.1 OAP65055.1 - 0.00079 19.5 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT BatD PF13584.1 OAP65055.1 - 0.0029 16.2 0.0 0.0036 15.9 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance DUF912 PF06024.7 OAP65055.1 - 0.0042 17.1 0.4 0.0042 17.1 0.3 1.7 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) CcmD PF04995.9 OAP65055.1 - 0.0054 16.4 1.4 0.0054 16.4 1.0 1.7 2 0 0 2 2 1 1 Heme exporter protein D (CcmD) EphA2_TM PF14575.1 OAP65055.1 - 0.0061 16.9 0.2 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2269 PF10027.4 OAP65055.1 - 0.0088 15.8 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DUF2615 PF11027.3 OAP65055.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) 7TM_GPCR_Srv PF10323.4 OAP65055.1 - 0.02 14.0 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF2207 PF09972.4 OAP65055.1 - 0.043 12.4 0.0 0.047 12.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Chordopox_A13L PF05961.6 OAP65055.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF2500 PF10694.4 OAP65055.1 - 0.053 13.5 0.1 0.089 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF4381 PF14316.1 OAP65055.1 - 0.055 13.5 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) YajC PF02699.10 OAP65055.1 - 0.068 12.8 0.1 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit DUF3529 PF12046.3 OAP65055.1 - 0.07 12.1 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) Vpu PF00558.14 OAP65055.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Vpu protein MscL PF01741.13 OAP65055.1 - 0.083 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL 7tm_1 PF00001.16 OAP65055.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1980 PF09323.5 OAP65055.1 - 0.12 12.1 0.2 0.17 11.5 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3377 PF11857.3 OAP65055.1 - 0.29 10.7 4.1 0.5 10.0 2.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) LNS2 PF08235.8 OAP65056.1 - 1.3e-70 236.0 0.0 2e-70 235.4 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 OAP65056.1 - 2.2e-38 130.3 0.0 4.5e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 OAP65056.1 - 0.01 15.2 0.0 0.27 10.5 0.0 2.6 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) FAM176 PF14851.1 OAP65056.1 - 6.8 6.3 7.8 15 5.2 5.4 1.5 1 0 0 1 1 1 0 FAM176 family TFIID-31kDa PF02291.10 OAP65057.1 - 2.6e-27 95.1 0.0 7e-26 90.5 0.0 2.2 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Fungal_trans PF04082.13 OAP65058.1 - 7.1e-18 64.4 0.3 1.1e-17 63.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP65058.1 - 1.8e-09 37.3 8.5 3.9e-09 36.2 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 OAP65059.1 - 1.7e-35 122.9 0.1 2.1e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 OAP65060.1 - 1.6e-26 92.8 25.6 1.6e-26 92.8 17.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily fn3 PF00041.16 OAP65060.1 - 6.5e-06 26.1 0.1 1.7e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain COG2 PF06148.6 OAP65060.1 - 1.6 8.6 19.5 0.084 12.7 2.6 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Thg1C PF14413.1 OAP65061.1 - 3.3e-44 149.4 7.3 3.7e-41 139.6 1.1 2.4 2 1 0 2 2 2 2 Thg1 C terminal domain Thg1 PF04446.7 OAP65061.1 - 2.3e-41 140.5 0.0 4.3e-41 139.6 0.0 1.5 1 1 0 1 1 1 1 tRNAHis guanylyltransferase Tom37_C PF11801.3 OAP65061.1 - 0.074 12.9 0.8 0.095 12.5 0.1 1.5 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF3381 PF11861.3 OAP65061.1 - 0.099 12.1 2.6 0.16 11.4 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CENP-B_dimeris PF09026.5 OAP65061.1 - 0.46 10.7 5.0 0.67 10.2 2.1 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3245 PF11595.3 OAP65061.1 - 0.74 10.0 8.2 1.4 9.2 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) CDC45 PF02724.9 OAP65061.1 - 3.5 5.5 5.8 5.6 4.8 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Aldedh PF00171.17 OAP65062.1 - 2.1e-117 392.2 0.2 2.6e-117 392.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 OAP65063.1 - 9.6e-18 63.9 0.0 5.2e-17 61.5 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF3425 PF11905.3 OAP65064.1 - 2.3e-23 82.5 0.3 5.1e-23 81.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAP65064.1 - 0.00045 20.1 6.5 0.00078 19.3 3.5 1.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 OAP65064.1 - 0.0066 16.2 3.5 0.013 15.2 2.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Leu_zip PF15294.1 OAP65064.1 - 0.097 11.7 0.4 0.16 11.0 0.3 1.2 1 0 0 1 1 1 0 Leucine zipper Rap1_C PF11626.3 OAP65064.1 - 0.21 11.4 1.6 0.59 10.0 1.1 1.7 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain adh_short PF00106.20 OAP65065.1 - 1.2e-29 103.3 0.1 1.9e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65065.1 - 2.2e-24 86.5 0.0 2.7e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65065.1 - 3.9e-13 49.4 0.1 6.9e-13 48.6 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP65065.1 - 1.4e-07 31.1 0.1 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP65065.1 - 0.00016 20.5 0.6 0.00022 20.0 0.3 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAP65065.1 - 0.0065 15.4 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UPF1_Zn_bind PF09416.5 OAP65065.1 - 0.33 10.5 1.5 0.62 9.6 0.3 1.8 1 1 1 2 2 2 0 RNA helicase (UPF2 interacting domain) Pyr_redox_3 PF13738.1 OAP65066.1 - 3.1e-23 82.8 0.0 7.1e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP65066.1 - 1.6e-18 66.1 0.3 7.9e-17 60.6 0.3 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP65066.1 - 7.9e-12 45.0 0.0 3.3e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP65066.1 - 2.9e-09 36.3 0.0 7.6e-08 31.6 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 OAP65066.1 - 0.0034 16.5 0.0 0.19 10.8 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 OAP65066.1 - 0.019 14.8 0.0 0.19 11.5 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 OAP65067.1 - 6.5e-29 99.8 0.8 1.1e-28 99.1 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP65067.1 - 9.2e-24 83.4 0.0 1.6e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 OAP65067.1 - 6.4e-05 22.5 0.1 0.00015 21.3 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 OAP65067.1 - 0.00045 21.0 0.0 0.001 19.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 OAP65067.1 - 0.0015 18.7 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 OAP65067.1 - 0.0016 18.5 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 OAP65067.1 - 0.0096 15.0 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 OAP65067.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CIAPIN1 PF05093.8 OAP65067.1 - 0.024 14.7 0.6 0.046 13.8 0.4 1.4 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pyr_redox_3 PF13738.1 OAP65067.1 - 0.03 14.3 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 OAP65067.1 - 0.15 11.8 2.8 0.64 9.8 1.1 2.3 1 1 1 2 2 2 0 ThiF family CorA PF01544.13 OAP65069.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein tRNA-synt_1d PF00750.14 OAP65070.1 - 7.3e-52 176.3 0.0 1.2e-51 175.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 OAP65070.1 - 1.5e-06 28.1 0.2 3.5e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 DALR anticodon binding domain Methyltransf_23 PF13489.1 OAP65072.1 - 0.00016 21.4 0.0 0.00051 19.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP65072.1 - 0.0011 19.5 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 OAP65072.1 - 0.017 14.8 0.0 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain ELL PF10390.4 OAP65072.1 - 0.022 13.9 0.2 0.033 13.4 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Methyltransf_31 PF13847.1 OAP65072.1 - 0.043 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 OAP65072.1 - 0.081 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Mito_carr PF00153.22 OAP65074.1 - 1.9e-46 155.6 8.9 2.7e-17 62.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RAM PF15320.1 OAP65076.1 - 1.7 8.9 10.6 0.22 11.8 3.9 2.1 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein RRM_1 PF00076.17 OAP65077.1 - 7.9e-16 57.4 0.0 1.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP65077.1 - 4e-11 42.7 0.0 6.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP65077.1 - 1.2e-10 41.0 0.0 1.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAP65077.1 - 0.0048 16.7 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif Gar1 PF04410.9 OAP65077.1 - 0.013 14.9 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region Corona_nucleoca PF00937.13 OAP65077.1 - 0.098 11.5 10.1 0.13 11.1 7.0 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PRP38_assoc PF12871.2 OAP65077.1 - 0.1 13.1 24.7 0.2 12.2 17.1 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 OAP65077.1 - 0.21 11.3 20.5 0.35 10.5 14.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF1469 PF07332.6 OAP65079.1 - 0.021 14.5 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) GTPase_Cys_C PF12631.2 OAP65079.1 - 0.051 13.9 0.4 5.3 7.5 0.2 3.3 3 0 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Motile_Sperm PF00635.21 OAP65080.1 - 1.7e-27 95.2 0.7 3.5e-27 94.2 0.5 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Herpes_UL49_2 PF04823.7 OAP65080.1 - 0.0014 18.5 1.6 0.003 17.5 1.1 1.5 1 0 0 1 1 1 1 Herpesvirus UL49 tegument protein DUF2077 PF09850.4 OAP65080.1 - 0.018 14.4 0.3 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) FixG_C PF11614.3 OAP65080.1 - 0.033 14.2 0.2 0.068 13.2 0.2 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase PapD-like PF14874.1 OAP65080.1 - 0.046 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like FlxA PF14282.1 OAP65080.1 - 0.082 12.8 8.0 0.17 11.8 5.5 1.5 1 0 0 1 1 1 0 FlxA-like protein HAUS6_N PF14661.1 OAP65080.1 - 0.084 12.2 2.9 0.14 11.4 2.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Golgin_A5 PF09787.4 OAP65080.1 - 0.26 9.7 6.1 0.32 9.4 4.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 PspA_IM30 PF04012.7 OAP65080.1 - 0.28 10.5 10.6 0.46 9.8 7.3 1.2 1 0 0 1 1 1 0 PspA/IM30 family Spectrin PF00435.16 OAP65080.1 - 0.37 11.1 3.9 0.19 12.0 0.9 1.8 2 0 0 2 2 2 0 Spectrin repeat ATG16 PF08614.6 OAP65080.1 - 0.55 10.0 4.7 0.81 9.4 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Herpes_UL32 PF06070.6 OAP65080.1 - 1.4 7.3 10.6 1.7 6.9 7.4 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Gly-zipper_OmpA PF13436.1 OAP65080.1 - 1.8 8.2 9.8 2.9 7.5 6.8 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain UBA PF00627.26 OAP65081.1 - 6e-06 25.9 0.1 1.8e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.15 OAP65081.1 - 0.00012 22.0 0.4 0.00027 20.9 0.0 1.8 2 0 0 2 2 2 1 UBX domain Crystallin PF00525.13 OAP65081.1 - 0.0069 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal Utp11 PF03998.8 OAP65081.1 - 0.2 11.4 28.4 0.31 10.8 19.7 1.3 1 0 0 1 1 1 0 Utp11 protein zf-C2H2_2 PF12756.2 OAP65081.1 - 0.22 11.6 0.1 0.22 11.6 0.1 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) EGF_alliinase PF04863.8 OAP65081.1 - 0.25 11.3 2.2 0.5 10.3 1.5 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain SOBP PF15279.1 OAP65081.1 - 0.25 11.6 7.6 0.28 11.5 5.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.7 OAP65081.1 - 0.37 10.6 25.4 0.56 10.0 17.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.14 OAP65081.1 - 0.41 8.4 7.5 0.51 8.1 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyD PF00529.15 OAP65081.1 - 6.5 5.9 22.4 11 5.2 15.5 1.3 1 0 0 1 1 1 0 HlyD family secretion protein FA_desaturase PF00487.19 OAP65084.1 - 4e-30 105.0 13.0 6.4e-30 104.4 9.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 OAP65084.1 - 1.5e-16 59.3 0.1 2.5e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DUF106 PF01956.11 OAP65084.1 - 0.55 9.7 3.2 1.2 8.6 2.2 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 MutS_V PF00488.16 OAP65085.1 - 1.1e-44 152.6 0.0 1.9e-43 148.5 0.0 2.1 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAP65085.1 - 1.7e-21 76.9 0.1 4.5e-21 75.5 0.0 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 OAP65085.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV adh_short PF00106.20 OAP65086.1 - 3.8e-16 59.4 0.0 8.3e-15 55.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65086.1 - 1.3e-05 25.1 0.0 8.8e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65086.1 - 1.9e-05 24.3 0.0 7.7e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 OAP65086.1 - 0.0047 16.9 0.1 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding DFP PF04127.10 OAP65086.1 - 0.017 14.7 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 OAP65086.1 - 0.043 13.2 0.0 0.097 12.0 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 OAP65086.1 - 0.059 12.4 0.1 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LytR_C PF13399.1 OAP65086.1 - 0.075 13.4 0.4 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Glyco_transf_4 PF13439.1 OAP65086.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Sas10 PF09368.5 OAP65087.1 - 2.5e-30 104.4 6.7 9.7e-30 102.5 4.6 2.1 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 OAP65087.1 - 2.4e-13 50.0 0.0 8.9e-13 48.2 0.0 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family TauD PF02668.11 OAP65088.1 - 1.8e-42 145.8 0.1 2.3e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 OAP65089.1 - 5.5e-10 38.4 19.1 5.8e-07 28.5 4.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 OAP65090.1 - 1e-36 126.4 29.7 1e-36 126.4 20.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP65090.1 - 5.8e-10 38.3 5.7 5.8e-10 38.3 4.0 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter FAD_binding_3 PF01494.14 OAP65091.1 - 4.6e-19 68.6 0.0 7.2e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP65091.1 - 5.6e-06 25.4 1.9 0.024 13.5 0.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 OAP65091.1 - 3.7e-05 23.0 0.0 6.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 OAP65091.1 - 8e-05 22.4 1.8 0.004 16.9 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAP65091.1 - 0.00015 21.6 1.1 0.00058 19.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 OAP65091.1 - 0.0032 16.3 0.0 0.023 13.5 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.9 OAP65091.1 - 0.0058 15.3 0.9 0.51 8.9 0.3 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 OAP65091.1 - 0.014 15.5 0.7 0.2 11.7 0.3 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAP65091.1 - 0.068 13.0 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF35 PF01796.12 OAP65091.1 - 0.13 12.5 0.1 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 DUF35 OB-fold domain PAF-AH_p_II PF03403.8 OAP65092.1 - 1.9e-40 138.3 0.0 1.4e-39 135.4 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 OAP65092.1 - 2.3e-11 43.6 0.1 4.2e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAP65092.1 - 1.7e-06 28.0 0.1 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAP65092.1 - 1.4e-05 24.1 0.1 0.0061 15.4 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.3 OAP65092.1 - 0.0021 17.8 0.1 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 OAP65092.1 - 0.03 13.1 0.0 0.12 11.1 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_2 PF02230.11 OAP65092.1 - 0.037 13.4 0.1 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase WD40_alt PF14077.1 OAP65092.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif p450 PF00067.17 OAP65093.1 - 1.7e-73 247.7 0.0 2.1e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Flu_NP PF00506.13 OAP65093.1 - 0.2 10.1 0.0 0.29 9.5 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein Abhydrolase_6 PF12697.2 OAP65094.1 - 4.6e-31 108.4 0.1 5.4e-31 108.2 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP65094.1 - 1.6e-15 57.3 0.1 1.3e-14 54.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP65094.1 - 3.7e-10 39.7 0.0 4.9e-10 39.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 OAP65094.1 - 0.0036 17.2 0.1 0.007 16.2 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Hydrolase_4 PF12146.3 OAP65094.1 - 0.005 16.6 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 OAP65094.1 - 0.14 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Zn_clus PF00172.13 OAP65095.1 - 0.0068 16.2 2.8 0.012 15.4 2.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIC3 PF15361.1 OAP65095.1 - 0.21 11.7 1.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Fungal_trans PF04082.13 OAP65096.1 - 2.5e-21 75.7 0.2 6.1e-21 74.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP65097.1 - 6.1e-38 130.4 28.7 6.1e-38 130.4 19.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cellulase PF00150.13 OAP65098.1 - 5.3e-06 25.8 1.8 0.0063 15.7 0.6 2.3 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Sugar_tr PF00083.19 OAP65099.1 - 5.6e-93 311.9 25.9 6.4e-93 311.7 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65099.1 - 2.5e-29 102.1 26.7 2.5e-29 102.1 18.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily ubiquitin PF00240.18 OAP65101.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family DIOX_N PF14226.1 OAP65102.1 - 1.8e-19 70.3 0.0 3.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP65102.1 - 5e-12 45.9 0.1 8.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 OAP65102.1 - 0.039 13.4 0.0 0.13 11.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) p450 PF00067.17 OAP65103.1 - 1.2e-52 179.0 0.0 1.8e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.8 OAP65104.1 - 1.8e-22 80.4 0.0 2.6e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.8 OAP65105.1 - 8.1e-22 78.2 0.0 1.2e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.20 OAP65106.1 - 2.8e-18 66.3 0.0 4.1e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65106.1 - 2.3e-10 40.6 0.0 3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65106.1 - 2.1e-07 30.7 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAP65106.1 - 0.0087 15.8 0.6 0.023 14.4 0.4 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_tran_WecB PF03808.8 OAP65106.1 - 0.077 12.3 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family PA PF02225.17 OAP65106.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 PA domain Shikimate_DH PF01488.15 OAP65106.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.13 OAP65107.1 - 3.6e-07 29.9 10.5 1.1e-06 28.4 7.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP65107.1 - 0.0004 19.3 0.4 0.0014 17.5 0.2 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Pro_CA PF00484.14 OAP65108.1 - 3e-18 66.2 0.1 4.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Zn_clus PF00172.13 OAP65109.1 - 1.4e-09 37.6 11.5 3e-09 36.6 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP65109.1 - 2.9e-05 22.8 0.0 4.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 OAP65111.1 - 1e-23 84.3 0.1 1.3e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP65111.1 - 2e-20 73.4 0.2 2.8e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65111.1 - 4.4e-08 32.9 0.3 1.2e-07 31.5 0.2 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 OAP65111.1 - 0.0095 15.3 0.4 0.12 11.8 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP65111.1 - 0.28 11.0 1.6 0.61 9.9 1.0 1.7 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UbiD PF01977.11 OAP65112.1 - 5e-130 433.6 0.0 5.7e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.14 OAP65113.1 - 1.1e-27 96.2 0.1 1.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein CPSase_L_chain PF00289.17 OAP65113.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain DIOX_N PF14226.1 OAP65114.1 - 4.8e-30 104.4 0.0 6.7e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP65114.1 - 8.8e-22 77.2 0.0 3.2e-21 75.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily LGFP PF08310.6 OAP65114.1 - 0.052 13.1 0.1 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 LGFP repeat DUF3433 PF11915.3 OAP65115.1 - 3.3e-16 59.2 4.0 4.1e-13 49.3 0.3 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) MgtE PF01769.11 OAP65115.1 - 2.2 8.5 7.1 0.72 10.1 0.1 3.0 3 0 0 3 3 3 0 Divalent cation transporter Thiolase_C PF02803.13 OAP65116.1 - 4.7e-09 35.7 0.1 1.7e-08 33.8 0.1 2.0 1 1 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 OAP65116.1 - 1.5e-07 30.9 0.0 3.4e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 OAP65116.1 - 0.00033 19.7 0.0 0.0073 15.3 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 OAP65116.1 - 0.022 14.5 0.1 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 OAP65116.1 - 0.063 12.7 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 OAP65117.1 - 2.9e-17 63.1 2.1 5.4e-17 62.2 1.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65117.1 - 3e-13 50.0 0.1 5.1e-13 49.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65117.1 - 0.0017 18.0 0.8 0.0047 16.6 0.1 1.8 2 0 0 2 2 2 1 KR domain Sugar_tr PF00083.19 OAP65117.1 - 0.075 11.5 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter Shikimate_DH PF01488.15 OAP65117.1 - 0.098 12.7 0.1 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 OAP65118.1 - 4.8e-13 48.5 0.1 5.5e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter FtsX PF02687.16 OAP65119.1 - 0.35 10.6 3.0 0.37 10.5 2.1 1.1 1 0 0 1 1 1 0 FtsX-like permease family Fungal_trans_2 PF11951.3 OAP65120.1 - 0.00037 19.1 0.1 0.00055 18.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chal_sti_synt_C PF02797.10 OAP65120.1 - 0.092 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain DUF3806 PF12713.2 OAP65122.1 - 0.15 11.5 0.4 1 8.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3806) IR1-M PF12185.3 OAP65123.1 - 0.99 9.1 4.1 0.34 10.6 0.2 2.0 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DUF3433 PF11915.3 OAP65124.1 - 1.7e-34 117.8 24.9 2.7e-25 88.3 1.4 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Sec62 PF03839.11 OAP65124.1 - 0.84 8.9 1.5 7.7 5.8 0.1 2.6 2 0 0 2 2 2 0 Translocation protein Sec62 Epimerase PF01370.16 OAP65125.1 - 1.1e-06 28.3 0.0 1.8e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP65125.1 - 9.1e-06 25.7 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding FMN_dh PF01070.13 OAP65126.1 - 8.6e-104 347.1 0.0 1.4e-103 346.4 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 OAP65126.1 - 2.6e-06 26.5 0.1 4.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 OAP65126.1 - 8.5e-06 24.9 0.1 6.5e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.16 OAP65126.1 - 0.00038 19.7 0.1 0.15 11.3 0.0 3.1 2 1 0 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.9 OAP65126.1 - 0.012 14.6 0.2 14 4.6 0.0 3.1 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.14 OAP65126.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family SdpI PF13630.1 OAP65127.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.0 2 0 0 2 2 2 0 SdpI/YhfL protein family PS_Dcarbxylase PF02666.10 OAP65128.1 - 2e-82 275.3 0.0 2.6e-81 271.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.18 OAP65129.1 - 5e-08 32.2 0.0 9.1e-08 31.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 OAP65129.1 - 4.1e-05 23.6 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2156 PF09924.4 OAP65130.1 - 8.1e-31 106.9 0.0 1.1e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) UBA_4 PF14555.1 OAP65131.1 - 0.002 17.6 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 OAP65131.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 LysM domain adh_short PF00106.20 OAP65132.1 - 7.4e-18 65.0 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65132.1 - 1.2e-06 28.5 0.0 1.5e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65132.1 - 1.2e-05 25.0 0.1 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAP65132.1 - 0.0022 18.0 0.0 0.0057 16.6 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 OAP65132.1 - 0.0051 15.9 0.0 0.0082 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ATPase_gene1 PF09527.5 OAP65132.1 - 0.052 13.3 0.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Eno-Rase_NADH_b PF12242.3 OAP65132.1 - 0.058 13.1 0.9 0.18 11.6 0.1 2.1 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SNF2_N PF00176.18 OAP65133.1 - 1.4e-66 224.3 1.1 2e-66 223.8 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP65133.1 - 3.6e-11 42.7 0.0 8.4e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 OAP65133.1 - 6.3e-08 32.2 1.1 1.8e-07 30.7 0.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 OAP65133.1 - 2.2e-07 30.4 3.3 4e-07 29.5 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP65133.1 - 4.1e-07 29.5 5.7 7.5e-07 28.7 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP65133.1 - 7.5e-07 28.8 5.8 1.4e-06 27.9 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP65133.1 - 9.6e-07 28.7 6.2 1.8e-06 27.8 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAP65133.1 - 1.7e-06 27.8 7.7 3.3e-06 26.8 5.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 OAP65133.1 - 8.1e-05 22.2 5.8 0.00015 21.4 4.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 OAP65133.1 - 0.051 13.1 4.9 0.12 11.9 3.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PhoH PF02562.11 OAP65133.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_34 PF13872.1 OAP65133.1 - 0.1 11.3 0.0 0.42 9.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 Pacs-1 PF10254.4 OAP65133.1 - 0.49 8.9 7.2 0.052 12.1 0.9 1.9 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein SPT6_acidic PF14632.1 OAP65133.1 - 1.9 8.6 14.2 0.2 11.8 5.7 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 MFS_1 PF07690.11 OAP65134.1 - 1.3e-11 43.8 43.9 1.3e-11 43.8 30.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_31 PF01055.21 OAP65135.1 - 5e-87 292.5 0.2 7.1e-87 292.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 OAP65135.1 - 8.7e-10 38.3 0.0 2.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.11 OAP65136.1 - 1e-33 116.5 29.5 1e-33 116.5 20.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP65137.1 - 4.5e-05 22.4 0.1 8.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 OAP65138.1 - 2.6e-71 240.2 0.0 3.3e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP65138.1 - 4.8e-06 27.4 0.0 3.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 OAP65139.1 - 3.9e-16 59.4 0.0 7.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65139.1 - 9.1e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Borrelia_P83 PF05262.6 OAP65140.1 - 0.22 9.7 11.0 0.31 9.2 7.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein ABC_membrane_2 PF06472.10 OAP65141.1 - 2.7e-95 318.7 0.5 3.9e-95 318.2 0.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 OAP65141.1 - 8e-15 55.3 0.0 1.5e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 OAP65141.1 - 0.02 14.3 0.3 0.38 10.3 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain 2-Hacid_dh_C PF02826.14 OAP65142.1 - 3.6e-54 182.6 0.0 4.8e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP65142.1 - 9.7e-17 60.6 0.0 1.2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP65142.1 - 0.0015 18.3 0.1 0.0035 17.2 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TRSP PF12500.3 OAP65142.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 AdoHcyase_NAD PF00670.16 OAP65142.1 - 0.14 11.9 0.4 0.96 9.2 0.3 2.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_N PF08240.7 OAP65143.1 - 1e-24 86.4 0.1 2e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP65143.1 - 9.2e-13 47.8 0.1 1.9e-12 46.8 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 OAP65143.1 - 0.0012 18.6 0.8 0.0028 17.4 0.5 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 OAP65143.1 - 0.0046 17.0 0.5 0.03 14.4 0.5 1.9 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 OAP65143.1 - 0.024 14.6 0.1 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP65143.1 - 0.071 12.1 1.2 0.11 11.5 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain Saccharop_dh PF03435.13 OAP65143.1 - 0.083 11.8 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 OAP65143.1 - 0.1 12.0 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 OAP65144.1 - 4.7e-36 124.2 0.0 5.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP65144.1 - 5.6e-15 55.8 0.1 7.9e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAP65144.1 - 1.2e-07 31.4 0.0 5.7e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAP65144.1 - 1.7e-05 23.6 0.0 2.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAP65144.1 - 0.0022 16.9 0.0 0.08 11.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 OAP65144.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TMEM171 PF15471.1 OAP65144.1 - 0.017 13.9 0.0 0.038 12.8 0.0 1.5 1 1 0 1 1 1 0 Transmembrane protein family 171 adh_short PF00106.20 OAP65144.1 - 0.026 14.4 0.4 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 OAP65144.1 - 0.037 13.9 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 OAP65144.1 - 0.14 11.0 0.0 7.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Cyt-b5 PF00173.23 OAP65146.1 - 1.5e-20 72.7 0.2 4.6e-19 68.0 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 OAP65146.1 - 6.8e-07 29.6 25.9 1.5e-06 28.5 17.7 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 OAP65146.1 - 0.042 13.8 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region YEATS PF03366.11 OAP65147.1 - 5.6e-13 48.4 0.6 1.3e-12 47.2 0.4 1.6 1 0 0 1 1 1 1 YEATS family zf-RING_2 PF13639.1 OAP65147.1 - 3.7e-07 29.8 6.6 6e-07 29.2 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAP65147.1 - 4.9e-07 29.5 3.0 4.9e-07 29.5 2.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 OAP65147.1 - 2.9e-06 27.1 7.7 1.4e-05 25.0 5.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAP65147.1 - 7e-06 25.6 5.3 1.4e-05 24.6 3.6 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP65147.1 - 1.6e-05 24.4 6.3 3.9e-05 23.2 4.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAP65147.1 - 0.00017 21.1 8.0 0.00078 19.0 5.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAP65147.1 - 0.0034 17.0 3.9 0.0034 17.0 2.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 OAP65147.1 - 0.031 13.7 6.8 0.037 13.5 2.2 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Glyco_hydro_30 PF02055.11 OAP65149.1 - 4.3e-27 94.4 0.0 6.8e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Fungal_trans PF04082.13 OAP65150.1 - 5.6e-10 38.5 0.0 1.3e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP65150.1 - 4.7e-06 26.4 9.4 8.2e-06 25.6 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 OAP65151.1 - 1.2e-29 103.3 0.0 1.5e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65151.1 - 2.8e-21 76.4 0.0 3.4e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65151.1 - 1.5e-12 47.5 0.0 2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP65151.1 - 0.00012 21.6 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP65151.1 - 0.0022 16.9 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 OAP65152.1 - 4.4e-87 292.5 20.7 5.1e-87 292.3 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65152.1 - 1.7e-21 76.3 37.8 1.9e-17 63.0 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 OAP65153.1 - 0.0006 18.7 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP65153.1 - 0.00099 18.9 12.6 0.0033 17.3 8.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 OAP65154.1 - 5.2e-23 81.3 55.6 5.3e-15 54.9 27.3 3.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 OAP65154.1 - 1.9e-12 46.2 5.8 1.9e-12 46.2 4.0 2.7 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAP65154.1 - 0.00011 20.9 2.6 0.00011 20.9 1.8 3.7 1 1 2 4 4 4 2 Sugar (and other) transporter DUF3624 PF12292.3 OAP65154.1 - 0.043 14.2 1.0 1 9.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) NADH-u_ox-rdase PF10785.4 OAP65154.1 - 3.6 7.8 10.6 0.51 10.6 0.4 3.9 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit HET PF06985.6 OAP65155.1 - 5.9e-15 55.6 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TMEM219 PF14940.1 OAP65156.1 - 0.25 10.4 4.1 0.061 12.4 0.6 1.6 2 0 0 2 2 2 0 Transmembrane 219 NPV_P10 PF05531.7 OAP65157.1 - 0.024 14.8 4.2 0.51 10.6 0.3 3.1 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Surfac_D-trimer PF09006.6 OAP65157.1 - 0.1 12.3 1.2 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Daxx PF03344.10 OAP65158.1 - 0.34 9.3 15.0 0.4 9.1 10.4 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAP65158.1 - 5.8 6.0 18.8 7.1 5.8 13.0 1.1 1 0 0 1 1 1 0 SDA1 GST_N_3 PF13417.1 OAP65159.1 - 1.3e-10 41.3 0.0 3.1e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP65159.1 - 3e-08 33.5 0.0 5.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP65159.1 - 0.019 14.8 2.1 0.028 14.3 0.7 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Dynein_light PF01221.13 OAP65160.1 - 9.2e-37 124.9 4.7 8.4e-31 105.8 0.6 2.0 2 0 0 2 2 2 2 Dynein light chain type 1 Ground-like PF04155.13 OAP65160.1 - 0.0065 16.7 0.1 0.0094 16.2 0.1 1.3 1 0 0 1 1 1 1 Ground-like domain UCH PF00443.24 OAP65160.1 - 0.095 11.7 0.1 0.095 11.7 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF2422 PF10337.4 OAP65161.1 - 2.6e-62 211.1 1.9 2.6e-62 211.1 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 OAP65161.1 - 2.8e-14 53.1 12.9 2.8e-14 53.1 8.9 3.3 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 OAP65161.1 - 3.3e-06 26.8 0.0 0.034 13.7 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF2421) ALMT PF11744.3 OAP65161.1 - 0.02 13.5 11.7 0.53 8.8 0.0 3.0 2 1 0 2 2 2 0 Aluminium activated malate transporter G0-G1_switch_2 PF15103.1 OAP65161.1 - 0.27 11.4 1.3 11 6.2 0.0 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 FUSC PF04632.7 OAP65161.1 - 2.1 6.6 23.8 0.28 9.5 0.4 3.7 3 1 0 3 3 3 0 Fusaric acid resistance protein family HET PF06985.6 OAP65162.1 - 2e-17 63.6 0.0 3.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aa_trans PF01490.13 OAP65163.1 - 3.3e-32 111.4 35.3 3.3e-32 111.4 24.5 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF810 PF05664.6 OAP65163.1 - 0.091 11.0 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF810) Transket_pyr PF02779.19 OAP65164.1 - 1.1e-41 142.2 0.0 1.9e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAP65164.1 - 3e-34 117.6 0.0 1.1e-33 115.7 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.15 OAP65165.1 - 4.8e-87 291.4 0.0 5.9e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 OAP65165.1 - 1e-06 27.8 0.8 7.4e-06 25.0 0.5 1.9 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.16 OAP65165.1 - 1.1e-05 24.9 0.1 6.7e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 OAP65165.1 - 0.00069 18.6 0.0 0.0014 17.6 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase 2-oxoacid_dh PF00198.18 OAP65166.1 - 1.6e-69 233.6 1.0 1.5e-68 230.4 0.2 2.0 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAP65166.1 - 1.9e-18 65.8 0.0 5.3e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 OAP65166.1 - 1.1e-12 47.3 0.3 2.3e-12 46.3 0.2 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 OAP65166.1 - 0.051 13.2 0.0 5.8 6.6 0.0 2.7 1 1 1 2 2 2 0 Biotin-lipoyl like Pectate_lyase_3 PF12708.2 OAP65167.1 - 1.1e-74 251.3 12.0 4.2e-59 200.4 5.0 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 OAP65167.1 - 2e-08 33.5 0.8 0.00096 18.5 0.0 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 OAP65167.1 - 0.0015 18.2 3.1 0.0015 18.2 2.2 2.2 1 1 1 2 2 2 1 Right handed beta helix region Abhydrolase_5 PF12695.2 OAP65168.1 - 0.00018 21.2 0.1 0.0006 19.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2828 PF11443.3 OAP65168.1 - 0.03 12.5 0.1 0.048 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PAE PF03283.8 OAP65168.1 - 0.1 11.1 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase Abhydrolase_2 PF02230.11 OAP65168.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DIOX_N PF14226.1 OAP65169.1 - 0.054 14.0 0.9 0.14 12.7 0.1 2.0 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal Pkinase PF00069.20 OAP65170.1 - 1.4e-37 129.2 0.0 2.2e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP65170.1 - 1.1e-20 73.8 0.0 1.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP65170.1 - 0.0041 16.8 0.1 0.011 15.5 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RRM_1 PF00076.17 OAP65171.1 - 3.6e-74 244.3 0.0 3.6e-19 68.1 0.0 5.6 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP65171.1 - 4.9e-56 186.6 0.0 3.6e-14 52.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP65171.1 - 1.6e-34 117.5 0.0 5.9e-08 32.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAP65171.1 - 0.0019 18.0 0.0 15 5.4 0.0 4.4 4 0 0 4 4 4 1 RNA binding motif TEA PF01285.13 OAP65172.1 - 2.8e-63 214.5 0.0 5.7e-63 213.5 0.0 1.3 1 1 0 1 1 1 1 TEA/ATTS domain family Histidinol_dh PF00815.15 OAP65173.1 - 1.8e-117 392.5 0.0 2.1e-117 392.2 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Herpes_capsid PF06112.6 OAP65174.1 - 7.2 6.6 16.9 11 6.0 11.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein NAD_binding_6 PF08030.7 OAP65175.1 - 1.8e-19 70.1 0.0 2.8e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAP65175.1 - 1.6e-15 56.8 0.0 3.5e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 OAP65175.1 - 1.1e-14 54.5 15.1 1.1e-14 54.5 10.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF1270 PF06900.6 OAP65175.1 - 0.81 9.8 7.9 0.61 10.2 0.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1270) Glyco_hydro_32N PF00251.15 OAP65177.1 - 1.8e-80 270.5 3.3 2.2e-80 270.3 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 OAP65177.1 - 0.0012 19.1 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sugar_tr PF00083.19 OAP65178.1 - 6.2e-126 420.5 26.9 7.2e-126 420.3 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65178.1 - 2.5e-17 62.6 40.8 3.3e-13 49.1 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VWA_2 PF13519.1 OAP65179.1 - 7.5e-06 26.1 0.0 2.3e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 OAP65179.1 - 0.00026 20.7 0.0 0.0012 18.6 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain YTH PF04146.10 OAP65180.1 - 1.2e-32 112.3 0.0 2.3e-32 111.4 0.0 1.5 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 OAP65180.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2613 PF11021.3 OAP65181.1 - 2.8 7.7 4.6 9.4 6.0 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) SSF PF00474.12 OAP65183.1 - 1.3e-19 70.1 27.6 1.9e-19 69.5 19.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Ibs_toxin PF13956.1 OAP65183.1 - 0.24 11.2 3.4 0.78 9.6 2.3 1.9 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system CheZ PF04344.8 OAP65184.1 - 0.008 15.8 1.3 0.018 14.7 0.1 2.1 2 1 0 2 2 2 1 Chemotaxis phosphatase, CheZ CDC37_N PF03234.9 OAP65184.1 - 9.2 6.5 9.1 0.98 9.7 1.1 2.8 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding D-ser_dehydrat PF14031.1 OAP65185.1 - 2.9e-25 88.2 0.0 5.4e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 OAP65185.1 - 4.3e-15 55.8 0.0 6.3e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3295 PF11702.3 OAP65187.1 - 1.5e-87 294.7 33.9 1.7e-87 294.5 23.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 OAP65187.1 - 2.8e-11 42.8 0.3 5e-11 41.9 0.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) zf-CHY PF05495.7 OAP65188.1 - 3.7e-15 55.8 16.3 3.7e-15 55.8 11.3 3.5 3 1 0 3 3 3 2 CHY zinc finger Cpn60_TCP1 PF00118.19 OAP65190.1 - 5.6e-147 490.2 4.2 6.4e-147 490.0 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 OAP65190.1 - 0.059 13.2 0.3 0.6 9.9 0.1 2.3 2 0 0 2 2 2 0 Resolvase, N terminal domain Enolase_N PF03952.11 OAP65190.1 - 0.12 12.3 2.1 5.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Enolase, N-terminal domain Chromo PF00385.19 OAP65192.1 - 1.5e-13 50.1 1.0 1.5e-13 50.1 0.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 OAP65192.1 - 1.8e-05 24.5 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Chromo shadow domain DUF3590 PF12148.3 OAP65192.1 - 0.0047 16.5 0.4 0.011 15.2 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3590) SAPS PF04499.10 OAP65192.1 - 3.4 6.1 6.0 3.6 6.1 4.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Myb_DNA-bind_2 PF08914.6 OAP65193.1 - 5e-16 58.2 0.6 1.5e-15 56.6 0.4 1.9 2 0 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.3 OAP65193.1 - 1.7e-14 53.4 0.1 7.7e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain GATA PF00320.22 OAP65193.1 - 7.5e-07 28.3 1.6 1.4e-06 27.4 1.1 1.5 1 0 0 1 1 1 1 GATA zinc finger Rap1-DNA-bind PF09197.5 OAP65193.1 - 7e-06 26.5 2.1 0.00036 21.0 0.1 3.0 2 0 0 2 2 2 1 Rap1, DNA-binding ArfGap PF01412.13 OAP65193.1 - 0.0085 15.8 1.6 0.029 14.1 1.1 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ICAP-1_inte_bdg PF10480.4 OAP65193.1 - 0.72 9.6 4.6 1.6 8.4 3.2 1.5 1 0 0 1 1 1 0 Beta-1 integrin binding protein Cyt-b5 PF00173.23 OAP65194.1 - 1.8e-23 82.0 0.1 2.5e-23 81.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VHS PF00790.14 OAP65195.1 - 7.1e-33 113.2 2.6 1.2e-32 112.5 1.8 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 OAP65195.1 - 3e-16 58.5 0.0 7.2e-16 57.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAP65195.1 - 7.6e-16 57.4 0.1 1.6e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAP65195.1 - 7e-15 54.2 0.0 1.3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 OAP65195.1 - 0.075 13.0 0.8 0.2 11.6 0.5 1.7 1 0 0 1 1 1 0 GAT domain UIM PF02809.15 OAP65195.1 - 0.095 12.3 1.3 0.24 11.0 0.9 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF445 PF04286.7 OAP65195.1 - 0.75 9.2 3.6 0.18 11.3 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Pkinase PF00069.20 OAP65196.1 - 5e-71 238.8 0.0 7.1e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP65196.1 - 3e-46 157.5 0.0 4.5e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 OAP65196.1 - 1.6e-15 57.2 0.3 9.1e-15 54.8 0.0 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 OAP65196.1 - 3.1e-06 26.3 0.0 4.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAP65196.1 - 0.04 13.6 0.1 0.4 10.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 OAP65196.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 OAP65196.1 - 0.17 10.9 0.8 0.43 9.6 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family COX15-CtaA PF02628.10 OAP65197.1 - 1.1e-97 326.5 10.4 1.1e-97 326.5 7.2 1.9 2 0 0 2 2 2 1 Cytochrome oxidase assembly protein Oxidored_FMN PF00724.15 OAP65198.1 - 2.3e-66 224.1 0.0 2.8e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HET PF06985.6 OAP65200.1 - 1.6e-16 60.7 0.0 3.9e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.26 OAP65201.1 - 7.9e-09 35.4 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF747 PF05346.6 OAP65202.1 - 3.5e-127 424.0 9.8 5.2e-127 423.4 6.8 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family tRNA-synt_2 PF00152.15 OAP65203.1 - 1.4e-88 296.8 0.5 2.2e-88 296.2 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAP65203.1 - 1e-11 44.5 0.0 3.1e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAP65203.1 - 2.3e-05 23.7 0.3 0.13 11.4 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 OAP65203.1 - 0.048 13.2 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) MAPEG PF01124.13 OAP65204.1 - 2.2e-24 85.5 2.1 2.9e-24 85.1 1.5 1.1 1 0 0 1 1 1 1 MAPEG family NTP_transferase PF00483.18 OAP65205.1 - 2.7e-29 102.1 0.0 4.1e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 OAP65205.1 - 7.4e-10 37.8 4.9 1.3e-05 24.4 0.0 3.7 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 OAP65205.1 - 1.5e-07 31.5 0.0 2.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 OAP65205.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2968 PF11180.3 OAP65205.1 - 0.17 11.2 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Pyridox_oxidase PF01243.15 OAP65206.1 - 1.5e-05 24.8 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF155 PF02582.9 OAP65207.1 - 5.5e-56 189.2 0.2 8.6e-56 188.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 E1_dh PF00676.15 OAP65208.1 - 1.5e-112 375.2 0.1 1.8e-112 374.9 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 OAP65208.1 - 3.8e-05 22.7 0.0 5.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Pkinase PF00069.20 OAP65209.1 - 9.2e-75 251.1 0.0 1.4e-74 250.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP65209.1 - 1.7e-35 122.3 0.0 2.6e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_11 PF08241.7 OAP65209.1 - 0.0021 18.5 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain APH PF01636.18 OAP65209.1 - 0.039 13.6 0.9 0.09 12.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 OAP65209.1 - 0.15 10.9 0.0 0.35 9.8 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 OAP65209.1 - 0.25 10.3 0.2 0.53 9.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GFA PF04828.9 OAP65210.1 - 7.4e-20 70.6 0.2 1.1e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Dynactin_p62 PF05502.8 OAP65210.1 - 0.047 12.4 0.9 0.075 11.7 0.3 1.4 1 1 0 1 1 1 0 Dynactin p62 family SAP PF02037.22 OAP65211.1 - 4.4e-12 45.1 0.1 7.2e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 SAP domain Packaging_FI PF14000.1 OAP65211.1 - 0.087 13.0 0.5 0.087 13.0 0.3 1.7 2 0 0 2 2 2 0 DNA packaging protein FI HeH PF12949.2 OAP65211.1 - 0.1 12.1 0.3 0.23 11.0 0.2 1.6 1 1 0 1 1 1 0 HeH/LEM domain TFIIA PF03153.8 OAP65211.1 - 1.1 9.0 5.3 1.3 8.8 3.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.5 OAP65211.1 - 1.3 8.1 12.1 1.8 7.7 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MFS_1 PF07690.11 OAP65212.1 - 5.4e-31 107.5 20.6 5.4e-31 107.5 14.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Hep_59 PF07052.6 OAP65213.1 - 1.5e-10 41.3 0.0 1.5e-10 41.3 0.0 2.7 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF1722 PF08349.6 OAP65213.1 - 0.013 15.3 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3847 PF12958.2 OAP65213.1 - 0.16 11.7 1.1 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Ribosomal_L12 PF00542.14 OAP65214.1 - 2e-19 69.3 3.2 2e-19 69.3 2.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DUF4349 PF14257.1 OAP65214.1 - 0.86 8.7 5.2 3.2 6.8 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) P5CR_dimer PF14748.1 OAP65215.1 - 2.9e-32 110.8 3.8 3.9e-32 110.4 1.4 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 OAP65215.1 - 2.9e-12 46.8 1.0 1.6e-10 41.2 0.0 2.9 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.3 OAP65216.1 - 3.7e-42 143.2 0.0 5.7e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 OAP65216.1 - 3.2e-16 59.1 6.9 7.2e-16 57.9 4.8 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Hat1_N PF10394.4 OAP65217.1 - 1.3e-34 119.6 0.0 2.1e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 OAP65217.1 - 0.036 14.1 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Zip PF02535.17 OAP65218.1 - 3.8e-40 137.8 19.1 4.1e-32 111.4 7.0 2.9 2 1 0 2 2 2 2 ZIP Zinc transporter PDR_assoc PF08370.6 OAP65218.1 - 0.087 12.3 0.7 0.29 10.6 0.0 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated WD40 PF00400.27 OAP65219.1 - 1.3e-53 177.0 25.3 9e-10 38.0 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 OAP65219.1 - 1.8e-08 33.0 11.3 0.062 11.4 0.1 5.7 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAP65219.1 - 0.00042 19.1 0.5 0.053 12.2 0.0 3.3 1 1 2 3 3 3 1 Nup133 N terminal like PQQ_2 PF13360.1 OAP65219.1 - 0.0057 16.1 4.4 0.27 10.6 0.2 3.4 1 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 OAP65219.1 - 0.014 15.6 7.6 13 6.1 0.1 6.4 5 2 3 8 8 8 0 PQQ-like domain Mito_carr PF00153.22 OAP65220.1 - 4.1e-50 167.4 3.5 2.3e-17 62.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 OAP65221.1 - 2.1e-10 39.8 0.0 5.1e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP65221.1 - 2.1e-08 33.9 7.6 4e-08 33.0 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 OAP65221.1 - 0.49 8.5 12.4 0.77 7.9 8.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1996 PF09362.5 OAP65222.1 - 2.3e-67 227.0 0.5 3e-67 226.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Homeobox_KN PF05920.6 OAP65224.1 - 1.3e-20 72.8 0.6 1.3e-20 72.8 0.4 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 OAP65224.1 - 7.7e-09 35.0 0.5 1.7e-08 33.9 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain FAD_binding_1 PF00667.15 OAP65225.1 - 6.1e-44 150.0 0.0 1e-43 149.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 OAP65225.1 - 1.5e-08 35.1 0.0 2.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Dmrt1 PF12374.3 OAP65225.1 - 3.7 7.9 15.1 0.23 11.8 6.4 2.1 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 GrpB PF04229.9 OAP65226.1 - 8.5e-48 162.2 0.0 9.9e-48 162.0 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Fungal_trans PF04082.13 OAP65227.1 - 2.3e-12 46.3 0.3 3.5e-12 45.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 OAP65227.1 - 6.5e-08 32.7 0.2 1.4e-05 25.2 0.0 2.6 2 1 0 2 2 2 1 NADH(P)-binding Zn_clus PF00172.13 OAP65227.1 - 1e-07 31.7 5.0 1e-07 31.7 3.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_4 PF07993.7 OAP65227.1 - 3.2e-05 22.9 0.0 5.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAP65227.1 - 0.0033 16.8 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP65227.1 - 0.023 13.6 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Med20 PF08612.6 OAP65228.1 - 4.8e-22 78.2 0.0 5.5e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_hydro_47 PF01532.15 OAP65229.1 - 5.5e-179 595.5 0.1 2.1e-178 593.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 OAP65229.1 - 0.004 15.4 0.1 0.24 9.6 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 OAP65229.1 - 0.0068 15.4 0.3 0.12 11.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 EF-1_beta_acid PF10587.4 OAP65229.1 - 0.04 14.0 0.7 0.073 13.2 0.5 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region CTD_bind PF04818.8 OAP65230.1 - 3.4e-21 75.2 0.1 8.1e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Dynactin_p22 PF07426.6 OAP65231.1 - 0.12 11.6 0.6 16 4.6 0.0 2.9 3 0 0 3 3 3 0 Dynactin subunit p22 Clathrin_lg_ch PF01086.12 OAP65232.1 - 3.3e-64 216.9 2.9 3.8e-64 216.7 2.0 1.0 1 0 0 1 1 1 1 Clathrin light chain ATP-synt_B PF00430.13 OAP65232.1 - 0.12 12.1 3.8 0.19 11.5 2.6 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RRF PF01765.14 OAP65232.1 - 2.3 7.6 6.8 3.1 7.2 4.7 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DUF1144 PF06610.8 OAP65233.1 - 0.16 11.7 1.6 10 5.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1144) NYD-SP28_assoc PF14775.1 OAP65233.1 - 0.6 9.8 5.7 0.15 11.7 0.5 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Ank_2 PF12796.2 OAP65234.1 - 2.4e-05 24.6 0.0 6.1e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Methyltransf_31 PF13847.1 OAP65234.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ank PF00023.25 OAP65234.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 OAP65234.1 - 0.038 14.5 0.0 7.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) adh_short PF00106.20 OAP65235.1 - 6.1e-30 104.3 0.3 7.8e-30 103.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65235.1 - 9.3e-23 81.2 0.2 1.1e-22 81.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65235.1 - 2e-09 37.3 0.4 3.3e-09 36.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP65235.1 - 0.0045 16.4 0.3 0.013 14.9 0.0 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family VBS PF08913.5 OAP65235.1 - 0.039 14.2 0.3 0.09 13.0 0.2 1.6 1 1 0 1 1 1 0 Vinculin Binding Site Indigoidine_A PF04227.7 OAP65236.1 - 3.5e-114 380.9 0.3 5.5e-114 380.3 0.2 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 OAP65236.1 - 2.1e-19 69.8 2.3 3.8e-11 42.6 0.0 2.7 3 0 0 3 3 3 2 pfkB family carbohydrate kinase SnoaL_2 PF12680.2 OAP65237.1 - 1.1e-08 35.3 0.2 4.6e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.7 OAP65237.1 - 2.6e-06 27.0 0.0 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4258 PF14076.1 OAP65239.1 - 0.04 13.9 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) DUF3328 PF11807.3 OAP65240.1 - 1.7e-55 188.0 0.1 2.1e-55 187.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SIS PF01380.17 OAP65241.1 - 2e-11 43.6 0.2 6.5e-11 41.9 0.1 1.9 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 OAP65241.1 - 0.1 12.2 0.1 0.45 10.2 0.1 1.9 1 1 1 2 2 2 0 SIS domain zf-C2H2_jaz PF12171.3 OAP65242.1 - 0.00024 21.1 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP65242.1 - 0.00094 19.2 0.2 0.0014 18.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3505 PF12013.3 OAP65242.1 - 0.0018 18.4 0.2 0.0048 17.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Fzo_mitofusin PF04799.8 OAP65242.1 - 0.014 14.7 0.2 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region zf-C2H2_2 PF12756.2 OAP65242.1 - 0.033 14.3 0.2 0.079 13.0 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) IncA PF04156.9 OAP65242.1 - 2.9 7.4 5.5 4.7 6.7 3.8 1.4 1 0 0 1 1 1 0 IncA protein TFIIS_M PF07500.9 OAP65243.1 - 7.7e-18 64.6 0.1 1.2e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 OAP65243.1 - 2.3e-15 57.0 0.0 5e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 OAP65243.1 - 1.5e-09 37.3 10.9 2.7e-09 36.5 7.6 1.5 1 0 0 1 1 1 1 PHD-finger DUF2296 PF10058.4 OAP65243.1 - 0.00045 19.8 5.7 0.00097 18.8 4.0 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) HTH_10 PF04967.7 OAP65243.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain PHD_2 PF13831.1 OAP65243.1 - 0.06 12.6 5.0 0.11 11.8 3.5 1.5 1 0 0 1 1 1 0 PHD-finger FF PF01846.14 OAP65244.1 - 1.1e-13 50.8 3.1 4.7e-10 39.2 0.0 2.8 2 0 0 2 2 2 2 FF domain WW PF00397.21 OAP65244.1 - 6.3e-10 38.7 9.6 4.7e-08 32.7 3.7 2.6 2 0 0 2 2 2 2 WW domain Thymopoietin PF08198.6 OAP65244.1 - 0.13 11.8 0.3 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Thymopoietin protein Proteasome PF00227.21 OAP65245.1 - 2.2e-60 203.1 0.0 2.7e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAP65245.1 - 3.2e-14 51.9 0.4 6.9e-14 50.8 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 OAP65245.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit HET PF06985.6 OAP65246.1 - 5e-12 46.1 0.0 7.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Carla_C4 PF01623.12 OAP65247.1 - 0.013 15.1 0.2 0.013 15.1 0.1 2.2 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein ADH_zinc_N_2 PF13602.1 OAP65248.1 - 2.2e-23 83.5 5.2 3.8e-23 82.7 0.7 3.0 2 2 1 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAP65248.1 - 7.9e-13 48.0 0.7 4.7e-12 45.5 0.2 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP65248.1 - 2.3e-05 24.1 0.0 0.00051 19.7 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 OAP65248.1 - 0.062 12.8 1.1 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Patatin PF01734.17 OAP65249.1 - 2.6e-21 76.4 0.3 8.1e-21 74.8 0.0 2.0 2 1 0 2 2 2 1 Patatin-like phospholipase DEAD PF00270.24 OAP65250.1 - 6.5e-39 133.1 0.0 1.4e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAP65250.1 - 1.1e-21 76.4 0.0 3e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 OAP65250.1 - 2.9e-07 29.2 0.1 7.5e-07 27.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) ResIII PF04851.10 OAP65250.1 - 0.0013 18.6 0.0 0.0013 18.6 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 OAP65250.1 - 0.0025 17.9 1.4 0.0093 16.1 0.5 2.4 1 1 1 2 2 2 1 AAA domain DUF3338 PF11819.3 OAP65250.1 - 0.0078 15.6 0.6 0.063 12.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) 3HCDH_N PF02737.13 OAP65250.1 - 0.082 12.5 0.1 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lyase_1 PF00206.15 OAP65251.1 - 5.1e-25 88.3 0.1 1.2e-24 87.0 0.0 1.6 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 OAP65251.1 - 3.7e-12 46.0 0.0 9.5e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Med7 PF05983.6 OAP65252.1 - 2.2e-37 128.3 0.8 3e-37 127.8 0.5 1.1 1 0 0 1 1 1 1 MED7 protein PAP2 PF01569.16 OAP65253.1 - 3.4e-24 84.9 1.3 3.4e-24 84.9 0.9 1.7 1 1 1 2 2 2 2 PAP2 superfamily DUF2104 PF09877.4 OAP65253.1 - 0.023 14.6 1.1 0.85 9.6 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) Sec62 PF03839.11 OAP65253.1 - 0.055 12.8 1.0 0.098 12.0 0.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RseC_MucC PF04246.7 OAP65253.1 - 0.12 11.9 0.4 15 5.1 0.0 2.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Pyr_redox_3 PF13738.1 OAP65254.1 - 3.6e-23 82.6 0.2 7.5e-22 78.3 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP65254.1 - 2.1e-18 65.8 0.0 1.3e-17 63.1 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP65254.1 - 1.4e-11 44.6 0.0 7.3e-10 39.0 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP65254.1 - 1.1e-08 34.3 0.0 9.7e-06 24.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 OAP65254.1 - 4.7e-07 30.1 5.3 0.0097 16.2 0.3 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP65254.1 - 1.2e-06 28.4 3.0 1.5e-06 28.1 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAP65254.1 - 2.5e-05 23.3 0.9 2.8e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 OAP65254.1 - 4.2e-05 23.6 0.2 0.2 11.7 0.1 2.6 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 OAP65254.1 - 0.00018 21.2 0.5 0.00029 20.5 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAP65254.1 - 0.00053 20.2 0.0 0.041 14.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 OAP65254.1 - 0.0036 16.4 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAP65254.1 - 0.0052 16.5 1.2 0.071 12.8 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAP65254.1 - 0.01 14.6 0.5 0.018 13.9 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 OAP65254.1 - 0.027 13.8 0.3 0.059 12.7 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 OAP65254.1 - 0.029 13.9 1.7 0.27 10.7 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 OAP65254.1 - 0.038 13.8 0.1 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.9 OAP65254.1 - 0.07 11.5 3.1 0.096 11.1 0.2 2.3 3 0 0 3 3 3 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 OAP65254.1 - 0.11 12.1 0.4 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 OAP65254.1 - 0.23 11.4 0.9 0.93 9.4 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding Thi4 PF01946.12 OAP65254.1 - 0.28 10.2 1.0 0.42 9.6 0.1 1.6 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 OAP65254.1 - 6 5.6 8.6 0.062 12.1 0.7 1.5 2 0 0 2 2 1 0 Glucose inhibited division protein A DUF3439 PF11921.3 OAP65256.1 - 0.0034 17.1 9.2 0.0064 16.2 6.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.12 OAP65256.1 - 0.016 15.0 14.2 0.016 15.0 9.8 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF642 PF04862.7 OAP65256.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF642) Nop14 PF04147.7 OAP65256.1 - 0.036 12.0 3.8 0.046 11.6 2.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 OAP65256.1 - 0.057 12.1 9.2 0.076 11.7 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Menin PF05053.8 OAP65256.1 - 0.4 8.7 4.1 0.51 8.4 2.8 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 OAP65256.1 - 0.43 8.8 9.0 0.48 8.6 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1510 PF07423.6 OAP65256.1 - 0.43 9.9 6.3 0.72 9.1 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Otopetrin PF03189.8 OAP65256.1 - 0.62 8.9 3.7 0.76 8.7 2.6 1.1 1 0 0 1 1 1 0 Otopetrin SSP160 PF06933.6 OAP65256.1 - 1.6 6.6 17.0 2.6 5.8 11.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MBOAT_2 PF13813.1 OAP65258.1 - 3.2e-09 36.7 1.4 7.5e-09 35.5 1.0 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short PF00106.20 OAP65259.1 - 2.6e-16 60.0 0.1 1.3e-15 57.6 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65259.1 - 1.3e-06 28.2 0.1 3.5e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAP65259.1 - 1.9e-06 27.8 0.1 7.8e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2470 PF10615.4 OAP65259.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) Polysacc_synt_2 PF02719.10 OAP65259.1 - 0.055 12.3 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SUR7 PF06687.7 OAP65260.1 - 1.5e-13 50.7 3.4 1.9e-13 50.4 2.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Abhydrolase_6 PF12697.2 OAP65261.1 - 5.5e-41 140.9 0.1 6.3e-41 140.7 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP65261.1 - 5.6e-29 101.3 0.0 6.6e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP65261.1 - 4.1e-26 91.4 0.1 2.4e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAP65261.1 - 8e-12 44.8 0.1 1.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 OAP65261.1 - 2.3e-09 36.7 0.0 0.00059 19.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 OAP65261.1 - 3.6e-06 26.5 0.0 1.1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.9 OAP65261.1 - 0.00015 20.3 0.0 0.07 11.6 0.0 2.1 2 0 0 2 2 2 2 Ndr family DLH PF01738.13 OAP65261.1 - 0.00034 19.9 0.0 0.0048 16.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family MTD PF01993.13 OAP65261.1 - 0.00043 19.4 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase AXE1 PF05448.7 OAP65261.1 - 0.0022 16.5 0.2 0.051 12.0 0.0 2.7 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 OAP65261.1 - 0.004 16.6 0.0 0.52 9.6 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 OAP65261.1 - 0.011 15.2 0.1 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ser_hydrolase PF06821.8 OAP65261.1 - 0.016 14.8 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase DUF915 PF06028.6 OAP65261.1 - 0.018 14.1 0.1 0.065 12.3 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1749 PF08538.5 OAP65261.1 - 0.035 12.9 0.1 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Acyl_transf_2 PF02273.10 OAP65261.1 - 0.042 12.8 0.0 0.2 10.6 0.0 1.8 2 0 0 2 2 2 0 Acyl transferase BAAT_C PF08840.6 OAP65261.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 OAP65261.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase PAF-AH_p_II PF03403.8 OAP65261.1 - 0.15 10.3 0.0 11 4.2 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 OAP65262.1 - 1.4e-25 90.5 0.1 1.8e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 OAP65262.1 - 5.1e-15 55.3 0.0 3.9e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 OAP65262.1 - 8.2e-15 54.9 0.0 2.9e-14 53.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP65262.1 - 5.9e-11 42.3 0.0 1.3e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP65262.1 - 2.3e-07 30.2 0.1 1.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 OAP65262.1 - 6.5e-07 29.2 0.0 4.8e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 OAP65262.1 - 2.5e-05 23.8 0.1 0.00022 20.7 0.1 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 OAP65262.1 - 0.00035 20.0 0.3 0.46 9.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.8 OAP65262.1 - 0.00067 19.3 0.0 0.0019 17.8 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.8 OAP65262.1 - 0.0013 18.3 0.0 0.081 12.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 OAP65262.1 - 0.0071 15.8 0.0 0.0083 15.5 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 OAP65262.1 - 0.016 14.6 0.0 0.18 11.2 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) UPF0227 PF05728.7 OAP65262.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2048 PF09752.4 OAP65262.1 - 0.029 13.2 0.0 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) DUF915 PF06028.6 OAP65262.1 - 0.094 11.7 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Aminotran_1_2 PF00155.16 OAP65263.1 - 4.3e-34 118.0 0.0 5.9e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2188 PF09954.4 OAP65263.1 - 0.35 10.8 1.2 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) RPN7 PF10602.4 OAP65264.1 - 1.2e-56 190.9 0.4 1.8e-56 190.3 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 OAP65264.1 - 1.3e-14 54.4 0.0 2.7e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 OAP65264.1 - 0.027 14.2 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAP65264.1 - 0.13 12.0 0.8 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 OAP65265.1 - 0.0037 16.9 5.9 0.011 15.3 4.1 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAP65265.1 - 0.032 13.9 0.3 0.079 12.6 0.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 OAP65265.1 - 1.8 8.6 6.9 0.25 11.3 1.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 OAP65265.1 - 2.4 7.7 7.7 2.8 7.5 0.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 OAP65265.1 - 2.7 7.8 11.7 1 9.2 5.3 2.5 1 1 1 2 2 2 0 Ring finger domain U-box PF04564.10 OAP65266.1 - 1.1e-14 54.0 0.0 2.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain VWA PF00092.23 OAP65267.1 - 1.4e-06 28.1 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 OAP65267.1 - 4.1e-05 23.7 0.0 5.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 OAP65267.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF1194 PF06707.6 OAP65267.1 - 0.016 14.2 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Sugar_tr PF00083.19 OAP65268.1 - 2.3e-37 128.6 31.4 1.6e-23 83.0 6.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP65268.1 - 3.3e-22 78.6 34.0 4.2e-13 48.7 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3169 PF11368.3 OAP65268.1 - 1.7 7.7 7.2 5.8 6.0 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) AMP-binding PF00501.23 OAP65269.1 - 3.7e-94 315.4 0.0 4.4e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP65269.1 - 6.8e-12 46.1 0.0 1.5e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PEX11 PF05648.9 OAP65270.1 - 1.8e-66 223.6 0.3 2e-66 223.4 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEPCK_ATP PF01293.15 OAP65271.1 - 9.7e-218 723.3 0.0 1.1e-217 723.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 OAP65271.1 - 0.01 16.1 0.0 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain HCMVantigenic_N PF12154.3 OAP65271.1 - 0.06 13.2 0.9 0.16 11.8 0.6 1.8 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV AAA_33 PF13671.1 OAP65271.1 - 0.085 12.7 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Metallophos PF00149.23 OAP65273.1 - 3.4e-11 42.9 2.0 2.7e-10 39.9 1.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAP65273.1 - 7.1e-09 35.6 0.0 1.6e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cupin_2 PF07883.6 OAP65274.1 - 1.2e-10 40.7 0.4 1.9e-10 40.0 0.3 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 OAP65274.1 - 1.4e-05 24.8 0.1 1.8e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 OAP65274.1 - 0.0014 18.3 0.5 0.0019 17.8 0.3 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 OAP65274.1 - 0.0036 16.6 0.5 0.011 15.1 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 OAP65274.1 - 0.073 12.5 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Cupin ABM PF03992.11 OAP65275.1 - 0.0031 17.4 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase UPF0560 PF10577.4 OAP65276.1 - 0.052 11.8 0.7 0.067 11.4 0.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 GMC_oxred_N PF00732.14 OAP65277.1 - 4.9e-61 206.4 0.0 6.1e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP65277.1 - 4.4e-31 108.1 0.0 6.5e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP65277.1 - 5.7e-06 25.4 0.1 0.026 13.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP65277.1 - 3.8e-05 22.7 0.1 6.5e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAP65277.1 - 0.0016 18.4 0.3 0.0035 17.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP65277.1 - 0.0065 14.9 0.0 0.011 14.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 OAP65277.1 - 0.012 15.6 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 OAP65277.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 OAP65277.1 - 0.35 11.3 1.1 3.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1989 PF09347.5 OAP65278.1 - 1.2e-34 119.1 0.0 1.5e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Zn_clus PF00172.13 OAP65279.1 - 7.2e-08 32.2 9.9 1.4e-07 31.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_EZ PF13513.1 OAP65280.1 - 6.2e-21 74.2 7.0 0.00011 22.5 0.1 9.7 8 2 1 9 9 9 5 HEAT-like repeat HEAT PF02985.17 OAP65280.1 - 2.3e-20 70.7 9.3 0.0018 18.2 0.1 9.5 11 0 0 11 11 8 3 HEAT repeat HEAT_2 PF13646.1 OAP65280.1 - 3.6e-18 65.6 10.6 2.7e-05 24.3 0.1 7.2 6 1 1 7 7 7 3 HEAT repeats IBN_N PF03810.14 OAP65280.1 - 7.8e-08 32.1 2.4 7.8e-08 32.1 1.7 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 OAP65280.1 - 2.3e-07 31.1 0.1 6.4 7.2 0.0 6.9 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAP65280.1 - 3.4e-07 29.8 0.1 0.059 12.7 0.0 4.4 4 1 0 4 4 4 2 CLASP N terminal UME PF08064.8 OAP65280.1 - 7.4e-05 22.6 0.1 8.6 6.3 0.0 6.2 5 2 3 8 8 8 1 UME (NUC010) domain Cnd1 PF12717.2 OAP65280.1 - 9.6e-05 22.3 9.5 0.24 11.2 0.0 6.1 6 3 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 OAP65280.1 - 0.0001 21.9 3.9 0.41 10.5 0.0 6.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 OAP65280.1 - 0.00035 19.4 7.6 0.0061 15.3 0.3 4.7 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal Cohesin_HEAT PF12765.2 OAP65280.1 - 0.004 17.0 0.1 3.3 7.7 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion WbqC PF08889.6 OAP65280.1 - 0.32 10.4 2.0 9.5 5.5 0.0 3.4 3 0 0 3 3 3 0 WbqC-like protein family SLAC1 PF03595.12 OAP65281.1 - 2.5e-87 292.6 56.6 3.2e-87 292.2 39.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DAD PF02109.11 OAP65281.1 - 7.7 6.6 8.0 1.2 9.2 1.3 2.4 2 0 0 2 2 2 0 DAD family Fungal_trans PF04082.13 OAP65282.1 - 0.027 13.3 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sec15 PF04091.7 OAP65282.1 - 0.055 12.7 0.9 0.85 8.8 0.6 2.0 1 1 0 1 1 1 0 Exocyst complex subunit Sec15-like MobC PF05713.6 OAP65282.1 - 0.13 12.2 0.9 0.3 11.0 0.2 2.0 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) Na_Ca_ex PF01699.19 OAP65283.1 - 3.1e-38 130.5 29.6 5e-22 78.0 7.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein LSM PF01423.17 OAP65284.1 - 6.4e-16 57.6 0.0 1.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 LSM domain Methyltransf_11 PF08241.7 OAP65284.1 - 1e-10 41.9 0.0 7.3e-10 39.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP65284.1 - 5.3e-08 32.7 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP65284.1 - 6.2e-08 32.3 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP65284.1 - 1.2e-07 32.0 0.0 3.4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP65284.1 - 2.4e-06 28.0 0.0 7.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP65284.1 - 4.4e-06 27.0 0.0 9.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SM-ATX PF14438.1 OAP65284.1 - 0.00041 20.2 0.1 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Methyltransf_26 PF13659.1 OAP65284.1 - 0.004 17.1 0.0 0.035 14.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PTH2 PF01981.11 OAP65284.1 - 0.11 12.2 0.3 0.34 10.5 0.2 1.9 1 1 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 API5 PF05918.6 OAP65284.1 - 0.21 10.0 17.7 0.47 8.8 12.2 1.5 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Cys_Met_Meta_PP PF01053.15 OAP65285.1 - 8.7e-26 90.1 0.0 2.6e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAP65285.1 - 8.7e-05 21.6 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II BLOC1_2 PF10046.4 OAP65286.1 - 0.025 14.7 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dopey_N PF04118.9 OAP65287.1 - 1.4e-107 359.0 0.0 3.3e-107 357.8 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal Mon1 PF03164.9 OAP65288.1 - 1.3e-115 386.3 0.0 1.6e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Miro PF08477.8 OAP65288.1 - 0.043 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Pyridoxal_deC PF00282.14 OAP65289.1 - 1.2e-30 106.2 0.0 5.9e-30 103.9 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SLA_LP_auto_ag PF05889.8 OAP65289.1 - 0.046 12.1 0.0 0.079 11.4 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) zf-CCCH_2 PF14608.1 OAP65290.1 - 3.2e-13 49.1 60.4 3.3e-05 23.6 6.8 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 OAP65290.1 - 0.00014 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DUF1216 PF06746.6 OAP65290.1 - 0.03 14.0 0.6 0.09 12.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Glyco_hydro_20 PF00728.17 OAP65291.1 - 5e-64 216.6 0.0 7.6e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain p450 PF00067.17 OAP65291.1 - 2.6e-61 207.5 0.0 3.4e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KH_1 PF00013.24 OAP65292.1 - 5.1e-88 288.6 23.6 3.7e-13 48.8 0.7 11.2 12 1 0 12 12 12 9 KH domain KH_3 PF13014.1 OAP65292.1 - 1.7e-56 187.0 31.9 4.2e-11 42.2 1.6 12.3 12 0 0 12 12 12 10 KH domain KH_2 PF07650.12 OAP65292.1 - 5.7e-14 51.4 23.2 0.015 14.8 0.2 7.8 5 2 2 7 7 7 5 KH domain KH_4 PF13083.1 OAP65292.1 - 1.7e-08 33.9 4.5 0.13 11.8 0.0 6.1 6 0 0 6 6 6 2 KH domain SLS PF14611.1 OAP65292.1 - 1e-07 31.6 12.8 0.16 11.3 0.0 7.9 6 4 4 10 10 10 2 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.1 OAP65292.1 - 0.00057 19.6 12.4 10 6.0 0.1 6.7 7 0 0 7 7 7 2 NusA-like KH domain DUF1664 PF07889.7 OAP65292.1 - 0.18 11.6 1.6 19 5.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FAD_binding_1 PF00667.15 OAP65293.1 - 2.1e-59 200.6 0.0 3.6e-59 199.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 OAP65293.1 - 1.2e-12 48.3 0.0 3.9e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 OAP65293.1 - 1.7e-08 34.5 0.1 4.9e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 OAP65293.1 - 2.1e-05 24.4 0.0 6.5e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain NAD_binding_10 PF13460.1 OAP65294.1 - 7e-10 39.2 0.0 9.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 OAP65294.1 - 0.00046 19.5 0.1 0.0015 17.8 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family DUF1471 PF07338.8 OAP65294.1 - 0.0026 17.3 0.1 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) Epimerase PF01370.16 OAP65294.1 - 0.014 14.8 0.0 0.099 12.0 0.0 2.0 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Cytadhesin_P30 PF07271.6 OAP65295.1 - 0.34 10.1 5.2 0.43 9.8 3.6 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 SDH_alpha PF03313.10 OAP65296.1 - 2.5e-91 305.6 0.3 4.3e-91 304.8 0.2 1.4 1 1 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 OAP65296.1 - 2.7e-50 170.5 0.0 4.9e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain MFS_1 PF07690.11 OAP65297.1 - 7.4e-30 103.8 32.0 2e-29 102.3 22.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Aldedh PF00171.17 OAP65298.1 - 1.9e-140 468.3 0.0 2.1e-140 468.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAP65298.1 - 0.012 14.3 0.0 0.039 12.6 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 OAP65298.1 - 0.099 11.8 0.0 0.76 8.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) adh_short PF00106.20 OAP65299.1 - 5e-13 49.3 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65299.1 - 6.1e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 OAP65299.1 - 0.00075 19.6 0.1 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 OAP65299.1 - 0.017 14.0 0.1 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GST_N_2 PF13409.1 OAP65300.1 - 2.2e-23 82.0 0.1 5e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP65300.1 - 2e-14 53.2 0.0 6e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP65300.1 - 1.2e-05 25.4 0.3 0.00042 20.4 0.2 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP65300.1 - 0.00093 19.1 0.0 0.0022 17.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAP65300.1 - 0.038 14.4 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MBOAT PF03062.14 OAP65301.1 - 8.9e-45 153.2 16.4 1.7e-44 152.2 11.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family zf-HIT PF04438.11 OAP65302.1 - 0.00092 18.8 4.6 0.0016 18.0 3.2 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF605 PF04652.11 OAP65302.1 - 0.0052 16.2 16.8 0.0061 16.0 11.6 1.1 1 0 0 1 1 1 1 Vta1 like WLM PF08325.5 OAP65303.1 - 6.7e-48 163.0 0.0 1.3e-47 162.0 0.0 1.5 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 OAP65303.1 - 3.9e-07 30.0 0.8 8.3e-07 28.9 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.2 OAP65303.1 - 0.85 9.4 5.1 5.1 7.0 3.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF605 PF04652.11 OAP65303.1 - 0.88 8.9 11.1 1.2 8.4 7.7 1.1 1 0 0 1 1 1 0 Vta1 like CAP59_mtransfer PF11735.3 OAP65304.1 - 3.7e-66 222.7 0.0 4.9e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Acyl-CoA_dh_1 PF00441.19 OAP65305.1 - 3.3e-13 50.0 0.4 3.4e-11 43.4 0.3 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAP65305.1 - 1.6e-07 30.6 0.3 0.022 14.2 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, middle domain GTP_EFTU PF00009.22 OAP65306.1 - 1.9e-09 37.2 0.0 6e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAP65306.1 - 0.072 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pkr1 PF08636.5 OAP65307.1 - 6.6e-34 115.8 5.3 9.1e-34 115.3 3.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 OAP65307.1 - 0.012 13.9 0.0 0.016 13.6 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family Kei1 PF08552.6 OAP65307.1 - 0.052 13.2 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 OAD_gamma PF04277.8 OAP65307.1 - 0.087 13.2 3.8 0.42 11.0 2.5 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CMV_1a PF12467.3 OAP65307.1 - 1.1 9.5 7.5 1.6 9.0 5.2 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family zf-C2H2 PF00096.21 OAP65308.1 - 0.00041 20.5 6.5 0.23 11.8 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP65308.1 - 0.0011 19.1 4.6 0.19 12.1 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger UPF0547 PF10571.4 OAP65308.1 - 0.022 14.4 0.2 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-C2H2_jaz PF12171.3 OAP65308.1 - 0.15 12.2 2.2 17 5.7 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAP65308.1 - 0.16 11.9 1.7 11 6.1 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger F-box-like PF12937.2 OAP65309.1 - 0.006 16.2 1.1 0.014 15.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 OAP65309.1 - 0.049 13.3 0.6 0.64 9.7 0.0 2.6 2 0 0 2 2 2 0 F-box-like domain F-box-like PF12937.2 OAP65310.1 - 6e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP65310.1 - 0.0009 18.8 0.5 0.0045 16.6 0.3 2.2 2 0 0 2 2 2 1 F-box domain Complex1_LYR PF05347.10 OAP65311.1 - 9.7e-10 38.0 0.1 1.6e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAP65311.1 - 3.6e-07 30.2 0.0 6.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 OAP65311.1 - 3.1e-05 24.3 0.5 4.8e-05 23.7 0.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Erythro_esteras PF05139.9 OAP65312.1 - 4.1e-130 434.0 5.5 4.8e-130 433.7 3.8 1.1 1 0 0 1 1 1 1 Erythromycin esterase HET PF06985.6 OAP65313.1 - 3.8e-15 56.2 2.3 3.8e-15 56.2 1.6 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CAP_N PF01213.14 OAP65313.1 - 1.7 7.8 4.1 2.7 7.2 2.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 OAP65313.1 - 8.2 5.7 9.2 0.37 10.1 2.4 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator Myb_DNA-bind_6 PF13921.1 OAP65314.1 - 8.1e-15 54.6 7.5 7.4e-11 41.9 1.4 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAP65314.1 - 4e-14 52.3 5.7 1.5e-06 28.1 1.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain zf-C2H2 PF00096.21 OAP65314.1 - 2.5e-08 33.7 17.0 0.00085 19.5 0.6 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP65314.1 - 2.2e-06 27.5 19.8 0.052 13.9 0.1 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAP65314.1 - 0.00075 19.5 8.2 0.0058 16.7 0.1 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAP65314.1 - 0.0072 16.4 8.5 0.24 11.6 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAP65314.1 - 0.032 14.3 11.3 0.14 12.2 0.7 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 OAP65314.1 - 0.061 13.0 8.3 0.66 9.7 0.2 3.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Elf1 PF05129.8 OAP65314.1 - 0.89 9.2 4.5 8.5 6.1 0.2 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like LIM PF00412.17 OAP65314.1 - 1.4 9.0 10.3 1.2 9.3 0.9 2.5 2 0 0 2 2 2 0 LIM domain zf-BED PF02892.10 OAP65314.1 - 9.3 6.1 7.7 3.9 7.3 0.6 2.8 2 0 0 2 2 2 0 BED zinc finger Vma12 PF11712.3 OAP65315.1 - 6.5e-35 119.9 0.0 8.9e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP_synt_I PF03899.10 OAP65315.1 - 0.0022 18.1 0.3 0.0038 17.3 0.2 1.3 1 0 0 1 1 1 1 ATP synthase I chain TT_ORF2 PF02957.10 OAP65315.1 - 0.14 12.8 0.0 0.35 11.5 0.0 1.5 2 0 0 2 2 2 0 TT viral ORF2 Amidohydro_1 PF01979.15 OAP65316.1 - 1e-23 84.5 0.1 5.2e-22 78.9 0.1 2.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAP65316.1 - 1.3e-18 68.0 0.0 2.6e-18 67.0 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 OAP65316.1 - 5.6e-09 35.6 0.1 1.3e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 OAP65316.1 - 5.3e-06 25.9 0.1 0.0081 15.4 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 OAP65316.1 - 0.018 14.5 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Amidohydrolase Mating_C PF12737.2 OAP65316.1 - 0.1 11.4 0.5 0.22 10.3 0.4 1.6 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 GFA PF04828.9 OAP65317.1 - 1.5e-18 66.5 0.1 1.9e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 OAP65317.1 - 0.025 14.3 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ADK_lid PF05191.9 OAP65317.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid Nudix_N_2 PF14803.1 OAP65317.1 - 1.4 8.6 4.2 4.3 7.1 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal Pyr_redox_3 PF13738.1 OAP65318.1 - 1.8e-21 77.1 0.0 5.4e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP65318.1 - 8.3e-16 57.8 0.1 9.9e-14 50.9 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 OAP65318.1 - 3.3e-12 45.3 0.0 2.4e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 OAP65318.1 - 5.6e-09 36.1 0.0 8.6e-08 32.2 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP65318.1 - 5.2e-05 22.4 0.1 0.0087 15.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.1 OAP65318.1 - 0.00014 21.6 2.3 0.59 9.8 0.1 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAP65318.1 - 0.00054 19.9 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP65318.1 - 0.023 13.6 0.1 0.096 11.5 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.19 OAP65318.1 - 0.096 11.5 0.2 6.8 5.4 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAP65318.1 - 0.1 13.0 0.2 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 OAP65320.1 - 8e-73 245.5 0.0 1.4e-72 244.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 EmrE PF13536.1 OAP65320.1 - 0.096 12.8 0.2 0.34 11.1 0.2 1.9 2 0 0 2 2 2 0 Multidrug resistance efflux transporter SURF6 PF04935.7 OAP65321.1 - 4.9e-47 159.9 37.0 4.9e-47 159.9 25.6 3.5 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 OAP65321.1 - 2.2e-20 72.4 1.2 2.2e-20 72.4 0.8 7.5 6 3 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 MHC_II_beta PF00969.14 OAP65321.1 - 0.52 10.3 2.0 3.1 7.8 0.0 3.1 2 1 1 3 3 3 0 Class II histocompatibility antigen, beta domain LysM PF01476.15 OAP65322.1 - 3.9e-11 42.6 0.0 4.3e-08 32.9 0.0 3.0 3 0 0 3 3 3 2 LysM domain Lysozyme_like PF13702.1 OAP65322.1 - 0.0013 18.2 0.3 0.003 17.0 0.2 1.5 1 1 0 1 1 1 1 Lysozyme-like SLT PF01464.15 OAP65322.1 - 0.0026 17.2 0.2 0.0092 15.4 0.1 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain TonB_C PF03544.9 OAP65322.1 - 0.0039 17.3 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal Sulfate_transp PF00916.15 OAP65323.1 - 1.1e-60 205.0 6.8 1.1e-60 205.0 4.7 2.0 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 OAP65323.1 - 1.1e-28 98.7 3.1 1.1e-28 98.7 2.2 3.5 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 OAP65323.1 - 2e-06 27.1 0.0 4.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain Lactamase_B PF00753.22 OAP65324.1 - 2.8e-13 49.9 1.7 8.3e-11 41.9 1.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAP65324.1 - 0.00067 19.2 0.1 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAP65324.1 - 0.039 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.9 OAP65325.1 - 2.3e-05 24.3 0.0 0.00018 21.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP65325.1 - 0.00077 19.2 0.0 0.0093 15.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAP65325.1 - 0.0043 17.1 0.0 0.025 14.6 0.1 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAP65325.1 - 0.006 15.5 0.2 0.0097 14.8 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Malic_M PF03949.10 OAP65325.1 - 0.032 13.7 0.1 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_binding_8 PF13450.1 OAP65325.1 - 0.14 12.1 0.4 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAP65325.1 - 0.16 10.8 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.11 OAP65326.1 - 7.7e-33 113.6 35.6 7.7e-33 113.6 24.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily cNMP_binding PF00027.24 OAP65327.1 - 1.2e-39 133.9 0.0 5.6e-20 70.9 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 OAP65327.1 - 2.3e-07 30.1 0.1 4.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Thioredoxin_6 PF13848.1 OAP65329.1 - 5.2e-25 88.3 0.1 6e-24 84.8 0.0 1.6 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 OAP65329.1 - 0.031 13.9 0.0 0.27 10.9 0.0 2.1 2 1 0 2 2 2 0 Thioredoxin 2OG-FeII_Oxy PF03171.15 OAP65330.1 - 0.0074 16.5 0.0 0.029 14.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily eRF1_1 PF03463.10 OAP65331.1 - 1.5e-46 157.2 0.0 2.9e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 OAP65331.1 - 1.5e-21 77.0 0.0 2.3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 OAP65331.1 - 2.1e-18 66.6 0.0 3.7e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 CCDC66 PF15236.1 OAP65332.1 - 0.13 11.8 18.0 0.27 10.8 12.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DIX PF00778.12 OAP65332.1 - 0.18 11.5 0.7 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 DIX domain MFS_1 PF07690.11 OAP65333.1 - 2.2e-39 135.1 35.2 2.2e-39 135.1 24.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP65333.1 - 3.9e-12 45.5 23.7 1.3e-10 40.4 16.5 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter Git3_C PF11970.3 OAP65333.1 - 1.1 9.0 4.8 7.1 6.4 0.8 3.1 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term NPR2 PF06218.6 OAP65334.1 - 9.4e-123 410.0 0.0 1.6e-122 409.3 0.0 1.4 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.8 OAP65334.1 - 0.029 12.9 0.0 1.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 MFS_1 PF07690.11 OAP65335.1 - 4.6e-25 88.0 34.1 4.6e-25 88.0 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP65335.1 - 0.00067 18.3 16.8 0.00067 18.3 11.6 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter Amidase PF01425.16 OAP65336.1 - 1.7e-78 264.4 0.0 2.2e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Amidase SGL PF08450.7 OAP65337.1 - 3.1e-31 108.6 0.1 6.7e-31 107.5 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 OAP65337.1 - 1.9e-05 24.5 0.0 0.0001 22.2 0.0 2.1 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.11 OAP65337.1 - 0.0009 19.2 0.0 0.0067 16.4 0.0 2.5 2 1 0 2 2 2 1 Strictosidine synthase NHL PF01436.16 OAP65337.1 - 0.0062 16.4 5.4 0.14 12.1 0.0 3.6 4 0 0 4 4 4 1 NHL repeat Reg_prop PF07494.6 OAP65337.1 - 0.076 13.0 0.5 4.2 7.7 0.1 3.2 2 0 0 2 2 2 0 Two component regulator propeller PALP PF00291.20 OAP65338.1 - 8e-66 222.3 0.0 1.2e-65 221.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.7 OAP65339.1 - 1e-46 158.3 0.0 1.4e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 OAP65339.1 - 2.6e-44 150.6 0.0 3.8e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 OAP65339.1 - 0.034 14.5 0.0 0.087 13.2 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Patatin PF01734.17 OAP65340.1 - 1.4e-26 93.6 0.3 3e-26 92.6 0.2 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.22 OAP65340.1 - 0.0011 19.2 0.0 0.0036 17.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 OAP65340.1 - 0.0013 18.6 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAP65340.1 - 0.0066 15.6 0.8 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 OAP65340.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 OAP65340.1 - 0.11 12.3 0.1 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.1 OAP65340.1 - 0.15 12.2 0.0 0.69 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 OAP65341.1 - 8.7e-95 315.8 49.2 5.4e-48 162.9 13.7 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 OAP65341.1 - 2.7e-40 137.8 0.0 1.1e-17 64.6 0.0 3.8 4 0 0 4 4 3 3 ABC transporter PDR_CDR PF06422.7 OAP65341.1 - 3e-38 129.6 1.3 1.2e-33 114.8 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 OAP65341.1 - 6.4e-20 71.0 0.2 1.6e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 OAP65341.1 - 6.7e-08 32.5 0.0 0.0049 16.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAP65341.1 - 1.6e-07 30.8 0.0 0.00031 20.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 OAP65341.1 - 2e-06 27.0 38.9 0.00029 20.0 11.2 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 OAP65341.1 - 7.4e-05 22.8 5.0 0.00083 19.3 0.1 3.3 4 0 0 4 4 3 1 AAA ATPase domain AAA_29 PF13555.1 OAP65341.1 - 9.4e-05 21.8 0.8 0.0082 15.6 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAP65341.1 - 0.00011 21.3 0.0 0.0072 15.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 OAP65341.1 - 0.00014 21.3 0.5 0.0041 16.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 OAP65341.1 - 0.00023 21.2 0.0 1.4 8.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 OAP65341.1 - 0.00025 21.8 0.0 0.98 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAP65341.1 - 0.0006 20.1 0.0 0.26 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP65341.1 - 0.0007 19.7 0.0 0.8 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 OAP65341.1 - 0.0013 18.0 0.0 0.35 10.0 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 OAP65341.1 - 0.0089 15.7 0.2 5.8 6.7 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 OAP65341.1 - 0.014 15.0 0.4 3.3 7.3 0.3 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 OAP65341.1 - 0.02 14.8 0.2 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 OAP65341.1 - 0.025 15.0 0.0 5.9 7.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 OAP65341.1 - 0.1 12.0 0.5 7.7 5.9 0.0 3.4 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA PF00004.24 OAP65341.1 - 0.14 12.3 0.0 27 4.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 OAP65341.1 - 0.17 11.5 0.8 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 OAP65341.1 - 0.21 11.7 0.0 26 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 OAP65341.1 - 0.22 11.0 1.7 7.3 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain BTB PF00651.26 OAP65342.1 - 2.1e-05 24.4 0.0 4.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain NAD_binding_10 PF13460.1 OAP65343.1 - 1.4e-08 34.9 0.0 1.8e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAP65343.1 - 0.00013 20.9 0.0 0.00023 20.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein DapB_N PF01113.15 OAP65343.1 - 0.00015 21.6 0.2 0.00044 20.1 0.2 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 OAP65343.1 - 0.0021 17.5 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAP65343.1 - 0.0025 16.7 0.0 0.0091 14.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 OAP65343.1 - 0.0039 15.9 0.0 0.0049 15.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAP65343.1 - 0.0073 16.2 0.0 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 OAP65343.1 - 0.0094 15.2 0.1 0.024 13.9 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 OAP65343.1 - 0.051 12.4 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 OAP65343.1 - 0.064 13.5 0.1 0.1 12.8 0.0 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 OAP65343.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 KR domain Chitin_synth_1 PF01644.12 OAP65344.1 - 1.1e-68 230.1 0.1 1.9e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase UQ_con PF00179.21 OAP65344.1 - 2.2e-35 121.1 0.0 3.9e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_2 PF03142.10 OAP65344.1 - 1.3e-27 96.4 0.0 4.7e-20 71.4 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 OAP65344.1 - 1.8e-27 94.8 0.1 3.5e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 OAP65344.1 - 3.9e-10 39.7 0.4 3.9e-10 39.7 0.3 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAP65344.1 - 3.9e-08 33.3 0.0 2.3e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Opy2 PF09463.5 OAP65345.1 - 4.2e-09 36.3 24.8 6.6e-09 35.7 17.2 1.3 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 OAP65345.1 - 0.0098 15.5 0.4 0.02 14.5 0.3 1.4 1 0 0 1 1 1 1 Syndecan domain Rifin_STEVOR PF02009.11 OAP65345.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Rifin/stevor family DNA_primase_S PF01896.14 OAP65346.1 - 5.8e-50 168.8 0.0 1.3e-49 167.7 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Amidohydro_2 PF04909.9 OAP65347.1 - 2.1e-45 155.3 0.1 2.5e-45 155.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 OAP65348.1 - 2.6e-11 42.8 0.0 4.3e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP65348.1 - 0.017 15.0 4.3 0.029 14.2 2.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP65349.1 - 6.8e-20 71.0 0.0 1e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP65349.1 - 6.2e-10 38.8 7.7 9.9e-10 38.1 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 OAP65350.1 - 3.7e-27 95.6 0.0 4.5e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP65350.1 - 1.3e-25 90.2 2.0 2.1e-25 89.5 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65350.1 - 4e-13 49.4 0.5 6.7e-13 48.6 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP65350.1 - 0.0051 16.2 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 OAP65351.1 - 4.8e-86 289.1 25.0 5.5e-86 288.9 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65351.1 - 4.1e-12 45.4 70.1 4.8e-11 41.9 24.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SLT PF01464.15 OAP65352.1 - 0.00091 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 OAP65352.1 - 0.0041 16.6 0.2 0.0041 16.6 0.1 2.4 2 1 1 3 3 3 1 Lysozyme-like Sugar_tr PF00083.19 OAP65353.1 - 2.3e-82 276.9 25.8 2.9e-82 276.6 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65353.1 - 4.2e-19 68.4 29.9 1.9e-17 63.0 16.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP65353.1 - 2.7e-06 26.0 26.2 2.6e-05 22.8 5.9 3.3 3 1 0 4 4 4 2 MFS/sugar transport protein Zn_clus PF00172.13 OAP65354.1 - 9.8e-09 34.9 9.6 1.8e-08 34.1 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAP65354.1 - 3.7e-05 22.7 0.6 0.00024 20.0 0.4 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain SnoaL PF07366.7 OAP65355.1 - 0.00067 19.2 0.0 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 OAP65355.1 - 0.0028 18.0 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain DEAD PF00270.24 OAP65356.1 - 3.7e-43 146.9 0.0 6.6e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 OAP65356.1 - 1.3e-22 79.0 0.1 2.4e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 OAP65356.1 - 3.3e-21 74.9 0.0 8e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP65356.1 - 0.11 12.2 1.0 0.33 10.7 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TIMELESS_C PF05029.8 OAP65356.1 - 0.4 9.5 10.7 0.61 8.9 7.4 1.2 1 0 0 1 1 1 0 Timeless protein C terminal region Pro-kuma_activ PF09286.6 OAP65357.1 - 3.9e-33 114.4 0.0 8.8e-33 113.3 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAP65357.1 - 7.5e-07 28.5 0.3 1.2e-06 27.8 0.2 1.4 1 0 0 1 1 1 1 Subtilase family Sarcoglycan_2 PF05510.8 OAP65357.1 - 0.082 11.1 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Pkinase PF00069.20 OAP65358.1 - 3.1e-70 236.3 0.0 3.8e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP65358.1 - 1.2e-31 109.6 0.0 1.7e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAP65358.1 - 0.018 14.7 1.0 0.05 13.3 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 OAP65358.1 - 0.073 12.1 0.0 0.19 10.7 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OTU PF02338.14 OAP65359.1 - 2.9e-18 66.6 0.0 2.9e-18 66.6 0.0 2.0 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 OAP65359.1 - 0.00018 20.9 0.8 0.39 10.0 0.0 2.9 2 1 1 3 3 3 2 Peptidase C65 Otubain Peptidase_C78 PF07910.8 OAP65359.1 - 0.14 11.2 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C78 TFIIA PF03153.8 OAP65359.1 - 0.34 10.7 10.5 0.46 10.3 7.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FluMu_gp41 PF10109.4 OAP65359.1 - 0.5 10.3 2.8 0.45 10.4 0.2 2.2 2 0 0 2 2 2 0 Mu-like prophage FluMu protein gp41 BAG PF02179.11 OAP65359.1 - 0.57 10.3 6.7 7.4 6.7 0.1 2.7 2 0 0 2 2 2 0 BAG domain Rib_recp_KP_reg PF05104.7 OAP65359.1 - 2.1 8.8 14.3 3.9 7.9 9.9 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region TPMT PF05724.6 OAP65360.1 - 7.3e-29 100.7 0.1 4.5e-28 98.1 0.0 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 OAP65360.1 - 1e-05 26.0 0.0 1.6e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP65360.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP65360.1 - 0.00018 21.8 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP65360.1 - 0.00075 19.9 0.0 0.0023 18.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAP65360.1 - 0.0012 18.5 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP65360.1 - 0.0034 16.9 0.1 0.0058 16.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 OAP65360.1 - 0.0089 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.7 OAP65360.1 - 0.061 12.2 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein MFS_1 PF07690.11 OAP65361.1 - 2.2e-45 154.9 49.1 5.9e-44 150.2 19.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 OAP65361.1 - 2.2e-05 22.7 2.5 0.074 11.0 0.0 3.3 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family COX4 PF02936.9 OAP65361.1 - 0.089 12.5 0.3 0.37 10.5 0.2 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV YqhR PF11085.3 OAP65361.1 - 0.88 9.0 0.0 0.88 9.0 0.0 2.8 3 0 0 3 3 3 0 Conserved membrane protein YqhR RseC_MucC PF04246.7 OAP65361.1 - 4.8 6.7 6.0 13 5.4 0.0 3.4 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC PT PF04886.7 OAP65362.1 - 0.3 10.4 62.8 0.32 10.3 4.9 7.5 4 2 0 4 4 4 0 PT repeat G_glu_transpept PF01019.16 OAP65363.1 - 3e-141 471.3 0.1 3.6e-141 471.1 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase 2OG-FeII_Oxy_4 PF13661.1 OAP65363.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_S10 PF00450.17 OAP65364.1 - 2e-93 313.8 0.1 2.5e-93 313.4 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyoxalase PF00903.20 OAP65365.1 - 1.6e-10 41.0 1.5 9.6e-07 28.8 0.7 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 OAP65365.1 - 5.3e-07 30.2 0.4 4.9e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 OAP65365.1 - 0.00016 21.6 0.3 0.0034 17.3 0.0 2.6 2 1 1 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAA_hydrolase PF01557.13 OAP65366.1 - 1.9e-57 194.1 0.0 2.6e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Catalase PF00199.14 OAP65367.1 - 3.1e-163 542.9 1.0 4.1e-163 542.5 0.7 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAP65367.1 - 7.1e-16 57.8 0.0 2.5e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive YscO PF07321.7 OAP65367.1 - 0.011 15.6 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO COesterase PF00135.23 OAP65368.1 - 1.1e-101 341.2 0.0 1.4e-101 340.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP65368.1 - 0.00028 20.5 0.1 0.0009 18.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAP65368.1 - 0.00089 18.5 0.1 0.0018 17.5 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Med1 PF10744.4 OAP65369.1 - 2.6e-40 138.4 0.0 1.5e-39 135.8 0.0 2.3 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Sugar_tr PF00083.19 OAP65370.1 - 6.7e-105 351.2 23.5 7.8e-105 351.0 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65370.1 - 1.9e-19 69.5 28.0 1.4e-14 53.6 1.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Herpes_LMP1 PF05297.6 OAP65370.1 - 1.7 7.4 3.7 2.8 6.7 2.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF427 PF04248.7 OAP65371.1 - 3.8e-34 116.2 0.0 6.4e-28 96.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) ECR1_N PF14382.1 OAP65374.1 - 3.2e-07 29.5 0.0 7.7e-07 28.2 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 OAP65374.1 - 0.00013 21.8 0.1 0.32 10.9 0.0 2.5 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 DUF367 PF04034.8 OAP65375.1 - 2.8e-48 162.7 0.0 3.9e-48 162.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 OAP65375.1 - 1.6e-09 37.1 0.3 3.5e-09 36.0 0.2 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PPV_E1_N PF00524.13 OAP65375.1 - 0.0028 17.8 0.2 0.0077 16.4 0.2 1.8 1 0 0 1 1 1 1 E1 Protein, N terminal domain GLTSCR1 PF15249.1 OAP65375.1 - 0.14 12.2 0.0 0.14 12.2 0.0 2.9 2 2 0 2 2 2 0 Glioma tumor suppressor candidate region Zn_clus PF00172.13 OAP65376.1 - 0.00011 22.0 3.7 0.0002 21.1 2.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Endostatin PF06482.6 OAP65376.1 - 2 7.7 4.7 0.34 10.2 0.4 1.7 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin bZIP_1 PF00170.16 OAP65377.1 - 3.2e-05 23.7 7.4 5.4e-05 23.0 5.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor Caprin-1_C PF12287.3 OAP65377.1 - 0.0028 17.0 0.5 0.0039 16.6 0.3 1.1 1 0 0 1 1 1 1 Cytoplasmic activation/proliferation-associated protein-1 C term bZIP_2 PF07716.10 OAP65377.1 - 0.0051 16.5 7.3 0.07 12.9 5.1 2.3 1 1 0 1 1 1 1 Basic region leucine zipper DUF2383 PF09537.5 OAP65377.1 - 0.014 15.5 0.3 0.028 14.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) AMP-binding PF00501.23 OAP65378.1 - 2e-75 253.7 0.0 2.6e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAP65378.1 - 7.5e-14 52.4 0.1 1.7e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_1 PF00583.19 OAP65379.1 - 1.3e-07 31.4 0.1 5.4e-07 29.5 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAP65379.1 - 0.014 15.4 0.0 0.085 12.9 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAP65379.1 - 0.069 13.3 0.1 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP65379.1 - 0.083 12.8 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP65379.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein ATG22 PF11700.3 OAP65381.1 - 1.5e-124 416.1 28.4 1.7e-124 415.9 19.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 OAP65381.1 - 1.5e-14 53.5 26.9 8.1e-08 31.3 0.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily FRQ PF09421.5 OAP65383.1 - 2.5e-83 280.4 47.7 2e-78 264.3 25.7 4.1 2 2 1 3 3 3 3 Frequency clock protein CoA_trans PF01144.18 OAP65384.1 - 9.7e-101 335.4 1.1 3.2e-60 203.0 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase HET PF06985.6 OAP65386.1 - 1.1e-30 106.6 0.0 2.8e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SOG2 PF10428.4 OAP65387.1 - 0.091 11.4 3.2 0.092 11.3 2.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein VSP PF03302.8 OAP65388.1 - 1.2e-05 24.1 0.9 1.7e-05 23.6 0.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.5 OAP65388.1 - 5.3e-05 22.4 0.6 0.00012 21.3 0.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 OAP65388.1 - 0.003 17.1 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.1 OAP65388.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Nitrate_red_gam PF02665.9 OAP65388.1 - 0.024 13.9 0.2 0.036 13.3 0.2 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FixQ PF05545.6 OAP65388.1 - 0.03 13.9 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Gly-zipper_OmpA PF13436.1 OAP65388.1 - 0.032 13.8 1.3 0.075 12.6 0.9 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Amnionless PF14828.1 OAP65388.1 - 0.034 12.6 0.0 0.052 12.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless AJAP1_PANP_C PF15298.1 OAP65388.1 - 0.041 13.7 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus EphA2_TM PF14575.1 OAP65388.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PepSY_TM_2 PF13703.1 OAP65388.1 - 0.06 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DUF2613 PF11021.3 OAP65388.1 - 0.075 12.7 7.7 0.096 12.4 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) DUF2668 PF10873.3 OAP65388.1 - 0.1 12.7 0.1 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) adh_short PF00106.20 OAP65389.1 - 1e-23 84.0 0.0 1.7e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65389.1 - 1.4e-06 28.1 0.0 3.6e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP65389.1 - 8.2e-05 22.4 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AA_permease_2 PF13520.1 OAP65391.1 - 1.3e-56 191.9 47.5 1.7e-56 191.6 32.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP65391.1 - 1.5e-29 102.6 41.5 1.9e-29 102.3 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2413 PF10310.4 OAP65393.1 - 4.7e-144 480.5 0.0 5.4e-144 480.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 OAP65393.1 - 0.058 13.4 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF605 PF04652.11 OAP65393.1 - 6.1 6.1 20.9 11 5.2 14.5 1.4 1 0 0 1 1 1 0 Vta1 like Transp_cyt_pur PF02133.10 OAP65395.1 - 1.4e-25 89.8 39.2 2e-25 89.2 27.2 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ATP_synth_reg PF14960.1 OAP65395.1 - 4.1 6.6 6.9 4.4 6.5 0.1 2.9 3 0 0 3 3 3 0 ATP synthase regulation Arylsulfotrans PF05935.6 OAP65396.1 - 1.7e-21 76.3 0.0 5.4e-11 41.6 0.0 2.1 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.1 OAP65396.1 - 9.6e-19 67.6 0.0 1.7e-18 66.8 0.0 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 OAP65396.1 - 0.029 13.8 0.0 0.14 11.6 0.0 2.0 2 1 0 2 2 2 0 PQQ-like domain THUMP PF02926.12 OAP65397.1 - 1e-10 41.6 0.3 2.3e-10 40.5 0.2 1.6 1 1 0 1 1 1 1 THUMP domain DUF948 PF06103.6 OAP65398.1 - 0.71 9.7 4.0 46 3.9 0.0 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Med9 PF07544.8 OAP65398.1 - 1.1 9.0 6.8 8.2 6.2 0.1 3.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 zf-C4H2 PF10146.4 OAP65398.1 - 1.5 8.7 11.9 0.072 13.0 1.0 3.5 3 2 0 3 3 3 0 Zinc finger-containing protein Spc7 PF08317.6 OAP65398.1 - 2 7.0 16.2 0.9 8.1 0.3 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 OAP65398.1 - 2.5 7.9 12.0 2.1 8.2 2.4 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 OAP65398.1 - 8.6 5.9 17.2 11 5.5 4.6 2.7 2 0 0 2 2 2 0 IncA protein GFO_IDH_MocA PF01408.17 OAP65400.1 - 6.3e-16 58.9 0.0 1e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribonuclease_T2 PF00445.13 OAP65401.1 - 5.7e-38 130.4 0.1 1.9e-37 128.7 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease T2 family MutS_V PF00488.16 OAP65404.1 - 1.4e-90 302.7 0.0 3e-90 301.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAP65404.1 - 2.1e-39 135.4 1.2 5.3e-39 134.1 0.8 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 OAP65404.1 - 1.8e-19 70.1 0.2 8.4e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 OAP65404.1 - 1.5e-17 63.5 0.5 4.9e-17 61.8 0.4 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 OAP65404.1 - 2e-14 53.5 0.0 2.6e-13 49.9 0.0 2.5 3 0 0 3 3 3 1 MutS domain I DUF2183 PF09949.4 OAP65405.1 - 2.7e-20 72.1 0.2 1.5e-19 69.7 0.0 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2183) B PF02216.11 OAP65405.1 - 0.18 11.5 0.1 0.42 10.4 0.0 1.6 2 0 0 2 2 2 0 B domain Aa_trans PF01490.13 OAP65406.1 - 7e-12 44.5 36.6 1.3e-08 33.8 16.3 2.2 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein OCIA PF07051.6 OAP65406.1 - 0.54 9.6 2.0 8.5 5.8 0.1 3.0 3 0 0 3 3 3 0 Ovarian carcinoma immunoreactive antigen (OCIA) Glyco_hydro_76 PF03663.9 OAP65407.1 - 1.9e-139 465.1 20.2 2.5e-139 464.8 14.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PCI_Csn8 PF10075.4 OAP65408.1 - 5.4e-41 139.7 0.0 7e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 OAP65408.1 - 3.9e-22 78.8 0.0 5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family XPC-binding PF09280.6 OAP65408.1 - 0.07 12.6 0.2 0.95 8.9 0.0 2.2 2 0 0 2 2 2 0 XPC-binding domain F-box-like PF12937.2 OAP65409.1 - 6.2e-15 54.6 0.8 4.7e-14 51.8 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAP65409.1 - 1.2e-06 27.9 2.2 2e-06 27.2 0.2 2.4 2 0 0 2 2 2 1 F-box domain DUF1265 PF06887.9 OAP65409.1 - 0.029 14.0 0.2 0.093 12.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) LRR_4 PF12799.2 OAP65409.1 - 0.078 12.6 6.6 0.85 9.3 0.3 4.1 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 OAP65409.1 - 0.71 10.4 3.3 17 6.0 1.3 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 OAP65409.1 - 0.75 10.0 7.3 2.8 8.2 0.1 5.0 6 0 0 6 6 6 0 Leucine Rich repeat MFS_1 PF07690.11 OAP65410.1 - 2.4e-29 102.1 40.3 2.4e-29 102.1 27.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SSXT PF05030.7 OAP65412.1 - 0.099 12.2 0.1 0.37 10.3 0.1 1.9 2 0 0 2 2 2 0 SSXT protein (N-terminal region) Pil1 PF13805.1 OAP65413.1 - 1.6e-100 335.7 2.6 2.6e-100 335.0 1.8 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 p450 PF00067.17 OAP65414.1 - 9.7e-46 156.2 0.0 2.4e-30 105.4 0.0 2.7 2 2 0 2 2 2 2 Cytochrome P450 DUF2306 PF10067.4 OAP65415.1 - 0.11 12.5 0.2 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) APG9 PF04109.11 OAP65416.1 - 3.9e-159 529.4 5.1 5.5e-159 529.0 3.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Zn_clus PF00172.13 OAP65417.1 - 3.7e-07 29.9 9.0 3.7e-07 29.9 6.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPO22 PF08631.5 OAP65417.1 - 0.051 12.6 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Glyco_hydro_47 PF01532.15 OAP65418.1 - 9.6e-173 574.9 0.0 1.2e-172 574.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 4HBT PF03061.17 OAP65418.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily Bacillus_HBL PF05791.6 OAP65418.1 - 0.14 11.5 0.1 0.33 10.3 0.0 1.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2013 PF09431.5 OAP65419.1 - 1.5e-53 180.3 0.8 2.8e-53 179.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Glyco_hydro_17 PF00332.13 OAP65420.1 - 4e-05 22.8 1.0 0.00043 19.4 0.1 2.2 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 AAA PF00004.24 OAP65421.1 - 1.6e-37 128.6 0.0 2.8e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 OAP65421.1 - 1.2e-06 28.2 0.0 1.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 OAP65421.1 - 5.7e-06 26.5 0.2 8.5e-05 22.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 OAP65421.1 - 1.5e-05 24.9 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 OAP65421.1 - 6.1e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 OAP65421.1 - 0.00037 20.2 0.0 0.001 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAP65421.1 - 0.001 19.1 0.4 0.0091 16.0 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 OAP65421.1 - 0.0011 17.7 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 OAP65421.1 - 0.0019 17.6 0.0 0.0043 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 OAP65421.1 - 0.0038 17.0 0.0 0.013 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAP65421.1 - 0.0038 16.4 0.1 0.0077 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 OAP65421.1 - 0.0078 15.6 0.3 0.25 10.7 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 OAP65421.1 - 0.008 15.9 0.0 0.026 14.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 OAP65421.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAP65421.1 - 0.023 15.5 0.1 0.1 13.4 0.0 2.2 2 1 0 2 2 1 0 AAA domain AAA_14 PF13173.1 OAP65421.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 OAP65421.1 - 0.04 12.8 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 OAP65421.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAP65421.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.16 OAP65421.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase Sigma54_activat PF00158.21 OAP65421.1 - 0.14 11.6 0.0 0.65 9.4 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 OAP65421.1 - 0.14 11.3 0.1 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Mito_carr PF00153.22 OAP65422.1 - 2.5e-72 238.6 5.5 9.9e-26 89.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein RAP1 PF07218.6 OAP65422.1 - 0.1 10.6 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IBR PF01485.16 OAP65423.1 - 4e-18 65.0 39.3 3.4e-10 39.6 10.6 4.5 3 1 1 4 4 4 2 IBR domain W2 PF02020.13 OAP65423.1 - 6.1e-15 54.9 5.9 2.1e-14 53.2 2.7 2.7 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 OAP65423.1 - 2.2e-08 33.2 14.3 0.003 16.9 0.4 4.1 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) zf-C3HC4_2 PF13923.1 OAP65423.1 - 1.6e-05 24.8 5.0 1.6e-05 24.8 3.5 4.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) NTP_transferase PF00483.18 OAP65423.1 - 0.0001 21.7 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase zf-C3HC4 PF00097.20 OAP65423.1 - 0.0004 19.9 4.2 0.0004 19.9 2.9 4.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Hexapep_2 PF14602.1 OAP65423.1 - 0.0018 17.8 15.8 0.018 14.6 2.1 3.4 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase zf-RING_5 PF14634.1 OAP65423.1 - 0.002 17.8 6.7 0.002 17.8 4.7 3.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAP65423.1 - 0.0049 16.6 4.9 0.0049 16.6 3.4 3.6 2 1 1 3 3 3 2 Ring finger domain NTP_transf_3 PF12804.2 OAP65423.1 - 0.0062 16.6 0.1 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain CRAL_TRIO PF00650.15 OAP65424.1 - 8.1e-40 135.9 0.0 1.3e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAP65424.1 - 2.8e-09 36.9 1.9 5.9e-09 35.9 0.2 2.3 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAP65424.1 - 5.1e-06 26.4 0.0 1.7e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 OAP65425.1 - 2e-10 40.8 1.8 2e-10 40.8 1.3 2.1 2 1 0 2 2 2 1 Kinetochore protein Mis14 like priB_priC PF07445.7 OAP65425.1 - 0.0026 17.2 2.0 0.0047 16.4 1.4 1.3 1 0 0 1 1 1 1 Primosomal replication protein priB and priC ubiquitin PF00240.18 OAP65426.1 - 1.5e-34 117.1 0.9 2.8e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 OAP65426.1 - 4.5e-27 93.6 3.5 9.3e-27 92.6 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 OAP65426.1 - 5.9e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAP65426.1 - 8.7e-06 25.9 0.2 4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAP65426.1 - 0.00012 21.8 0.1 0.0002 21.1 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAP65426.1 - 0.00068 19.4 0.7 0.0015 18.4 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAP65426.1 - 0.0043 17.2 0.5 0.0059 16.7 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 OAP65426.1 - 0.049 13.6 0.6 0.098 12.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) IBR PF01485.16 OAP65426.1 - 0.081 12.8 0.5 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 OAP65426.1 - 0.086 11.1 2.4 2 6.6 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain zf-H2C2_2 PF13465.1 OAP65427.1 - 6.5e-10 38.7 12.7 0.00011 22.2 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAP65427.1 - 2e-07 30.9 23.4 0.0063 16.7 0.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAP65427.1 - 0.0013 18.8 20.3 0.025 14.9 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger POP1 PF06978.6 OAP65427.1 - 0.054 13.1 1.2 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 Bunya_G2 PF03563.8 OAP65427.1 - 0.2 10.5 3.1 0.3 9.9 2.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_jaz PF12171.3 OAP65427.1 - 6.8 6.9 11.5 3.5 7.8 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding YolD PF08863.5 OAP65428.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 YolD-like protein Transthyretin PF00576.16 OAP65429.1 - 1.5e-24 86.0 0.2 4.8e-24 84.3 0.1 1.7 1 1 0 1 1 1 1 HIUase/Transthyretin family Sugar_tr PF00083.19 OAP65430.1 - 1.8e-82 277.3 16.0 2.9e-82 276.6 11.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65430.1 - 6.4e-23 81.0 46.9 2.3e-16 59.4 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 OAP65431.1 - 0.0026 17.7 0.1 0.0059 16.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 OAP65431.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 OAP65431.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RRM_1 PF00076.17 OAP65433.1 - 1.9e-50 168.3 0.0 2.9e-18 65.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP65433.1 - 5.2e-42 141.6 0.0 2.9e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP65433.1 - 1e-22 79.7 0.0 5.5e-07 29.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAP65433.1 - 0.00017 21.2 0.1 3.5 7.4 0.0 3.9 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 OAP65433.1 - 0.00035 20.3 0.0 7.4 6.4 0.0 3.6 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.5 OAP65433.1 - 0.0022 17.3 0.0 0.19 11.0 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain SPOR PF05036.8 OAP65433.1 - 0.0027 17.8 0.3 0.55 10.4 0.0 3.5 3 1 1 4 4 4 1 Sporulation related domain DUF3304 PF11745.3 OAP65433.1 - 0.076 13.2 0.0 0.076 13.2 0.0 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3304) COQ9 PF08511.6 OAP65434.1 - 3.8e-31 106.4 0.2 6.1e-31 105.7 0.1 1.3 1 0 0 1 1 1 1 COQ9 BBP1_C PF15272.1 OAP65435.1 - 0.014 14.9 0.7 0.014 14.9 0.5 1.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Racemase_4 PF13615.1 OAP65435.1 - 0.072 13.3 1.8 0.088 13.0 0.1 1.9 2 0 0 2 2 2 0 Putative alanine racemase DivIVA PF05103.8 OAP65435.1 - 0.1 12.6 3.8 0.11 12.5 1.1 2.0 2 0 0 2 2 2 0 DivIVA protein SlyX PF04102.7 OAP65435.1 - 0.26 11.6 10.3 6.2 7.2 1.2 3.5 2 1 1 3 3 3 0 SlyX ATG16 PF08614.6 OAP65435.1 - 7.2 6.3 14.0 4.3 7.1 6.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Bromodomain PF00439.20 OAP65436.1 - 2.1e-36 123.6 4.7 3e-18 65.5 0.5 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 OAP65436.1 - 2.6e-17 62.6 1.1 8.1e-17 61.0 0.8 1.9 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.9 OAP65436.1 - 2.3 6.1 16.0 0.028 12.4 5.5 1.8 2 0 0 2 2 2 0 CDC45-like protein OTU PF02338.14 OAP65437.1 - 5.8e-13 49.4 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 OAP65437.1 - 0.0054 16.1 0.1 0.015 14.6 0.1 1.6 1 1 1 2 2 2 1 Peptidase C65 Otubain UBX PF00789.15 OAP65437.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 UBX domain Choline_kin_N PF04428.9 OAP65437.1 - 0.11 11.9 0.1 2.4 7.7 0.0 2.8 3 0 0 3 3 3 0 Choline kinase N terminus Abhydrolase_3 PF07859.8 OAP65438.1 - 4.3e-51 173.4 0.0 5.3e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP65438.1 - 1.2e-12 47.3 0.0 3.1e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAP65438.1 - 5e-05 23.0 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 OAP65438.1 - 0.00031 19.4 0.0 0.0004 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 OAP65438.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP65438.1 - 0.036 13.2 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAP65438.1 - 0.038 13.5 0.0 0.094 12.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.15 OAP65438.1 - 0.052 12.9 0.1 0.26 10.6 0.1 2.1 2 1 0 2 2 2 0 Putative esterase COG6 PF06419.6 OAP65439.1 - 4.2e-168 560.2 0.6 4.7e-168 560.1 0.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF4570 PF15134.1 OAP65439.1 - 0.0027 17.5 0.8 0.077 12.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4570) COG2 PF06148.6 OAP65439.1 - 0.17 11.7 2.6 0.8 9.5 0.2 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Redoxin PF08534.5 OAP65440.1 - 4.7e-29 100.8 0.0 5.2e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAP65440.1 - 1.5e-09 37.6 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.12 OAP65441.1 - 9.6e-38 128.5 0.7 9.6e-38 128.5 0.5 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 OAP65441.1 - 7.6e-23 80.6 0.1 1.6e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain BLOC1_2 PF10046.4 OAP65441.1 - 0.0061 16.6 4.8 0.028 14.5 3.3 2.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 OAP65441.1 - 2 7.9 10.2 0.9 9.0 1.2 2.4 2 0 0 2 2 2 0 Septum formation initiator BolA PF01722.13 OAP65442.1 - 9.1e-19 67.2 0.0 1.2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 OAP65443.1 - 1e-54 185.6 0.0 1.7e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) AA_permease_C PF13906.1 OAP65444.1 - 1.2 9.0 6.8 1.9 8.4 4.7 1.3 1 0 0 1 1 1 0 C-terminus of AA_permease Asp PF00026.18 OAP65445.1 - 2.7e-58 197.7 2.9 2.7e-58 197.7 2.0 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease Kinesin PF00225.18 OAP65448.1 - 4.7e-85 285.2 0.1 7.3e-85 284.6 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.2 OAP65448.1 - 1e-06 28.5 0.0 3.6e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 OAP65448.1 - 7.9e-05 22.7 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.18 OAP65448.1 - 0.00057 19.4 0.1 0.98 9.2 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif MARVEL PF01284.18 OAP65450.1 - 0.0019 18.0 15.1 0.0036 17.1 10.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain Abhydrolase_6 PF12697.2 OAP65451.1 - 6.8e-18 65.3 0.4 1.3e-17 64.4 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP65451.1 - 2e-09 37.3 0.0 8.8e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP65451.1 - 7.4e-07 29.0 0.1 2.9e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 OAP65451.1 - 0.00074 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Microtub_assoc PF07989.6 OAP65452.1 - 4.2e-26 90.5 7.5 4.2e-26 90.5 5.2 13.9 10 4 5 15 15 15 2 Microtubule associated PACT_coil_coil PF10495.4 OAP65452.1 - 4.6e-17 61.7 0.5 1.7e-16 59.9 0.4 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 OAP65452.1 - 0.0012 18.7 22.0 0.0012 18.7 15.3 12.8 1 1 11 13 13 13 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 OAP65452.1 - 0.028 12.1 229.1 0.013 13.2 64.2 5.4 1 1 2 4 4 4 0 Myosin tail Reo_sigmaC PF04582.7 OAP65452.1 - 1.3 8.1 62.4 0.15 11.2 4.6 8.3 1 1 9 11 11 11 0 Reovirus sigma C capsid protein Filament PF00038.16 OAP65452.1 - 1.4 8.2 193.9 0.22 10.9 7.3 8.3 1 1 5 7 7 7 0 Intermediate filament protein SGT1 PF07093.6 OAP65453.1 - 1.3e-139 466.3 17.7 1.1e-137 460.0 12.3 2.1 1 1 0 1 1 1 1 SGT1 protein EHN PF06441.7 OAP65454.1 - 1.3e-34 118.5 2.6 3.5e-34 117.0 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAP65454.1 - 1.7e-13 50.9 0.0 3.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP65454.1 - 2.4e-08 33.8 0.0 9.8e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold JAB PF01398.16 OAP65455.1 - 1.5e-14 53.7 0.0 2.8e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 OAP65455.1 - 3.2e-11 43.1 0.3 3.2e-11 43.1 0.2 1.7 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.1 OAP65455.1 - 2.5e-06 26.9 0.1 8.5e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain WSC PF01822.14 OAP65456.1 - 8.4e-15 54.4 11.4 8.4e-15 54.4 7.9 1.8 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 OAP65456.1 - 6.8e-06 25.2 2.0 6.8e-06 25.2 1.4 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 OAP65456.1 - 0.0066 14.7 0.0 0.0086 14.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4366 PF14283.1 OAP65456.1 - 0.11 11.8 0.2 0.97 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) TBCC PF07986.7 OAP65457.1 - 1.1e-33 115.1 0.7 1.6e-33 114.6 0.5 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C RrnaAD PF00398.15 OAP65458.1 - 4.8e-05 22.5 0.0 0.0018 17.3 0.0 2.6 4 0 0 4 4 4 2 Ribosomal RNA adenine dimethylase Isochorismatase PF00857.15 OAP65459.1 - 7.6e-19 68.2 0.4 7e-14 52.1 0.1 3.1 2 1 0 2 2 2 2 Isochorismatase family HET PF06985.6 OAP65461.1 - 3e-07 30.6 0.1 5.3e-05 23.3 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pro_CA PF00484.14 OAP65463.1 - 1.5e-15 57.5 0.0 2.1e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Apc3 PF12895.2 OAP65465.1 - 0.013 15.6 0.5 1.4 9.1 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 OAP65465.1 - 0.063 13.0 1.1 0.51 10.2 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP65465.1 - 0.067 13.1 0.2 1.5 8.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Med2 PF11214.3 OAP65465.1 - 0.077 13.0 1.2 1.1 9.2 0.4 2.6 2 1 0 3 3 3 0 Mediator complex subunit 2 TPR_19 PF14559.1 OAP65465.1 - 0.09 13.1 1.5 7.3 7.0 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Paf67 PF10255.4 OAP65465.1 - 0.83 8.4 4.5 0.33 9.7 0.2 2.2 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 adh_short PF00106.20 OAP65466.1 - 1e-21 77.5 0.1 1.3e-21 77.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65466.1 - 4.7e-11 42.6 0.1 5.9e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 KR domain HHV6-IE PF03753.8 OAP65466.1 - 0.11 10.0 0.0 0.13 9.6 0.0 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein DDE_Tnp_IS1 PF03400.8 OAP65466.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 IS1 transposase NifU_N PF01592.11 OAP65467.1 - 1.2e-52 177.1 0.1 1.6e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain PC4 PF02229.11 OAP65468.1 - 2.6e-22 77.8 0.4 4.6e-22 77.0 0.3 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Hydantoinase_B PF02538.9 OAP65469.1 - 3.7e-202 672.2 0.1 2e-200 666.4 0.1 2.1 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 OAP65469.1 - 9e-97 323.6 0.2 3.5e-96 321.7 0.1 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 OAP65469.1 - 1.3e-57 194.1 0.6 6.7e-56 188.5 0.0 2.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Pkinase PF00069.20 OAP65470.1 - 1.7e-69 233.8 0.0 2.1e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP65470.1 - 1.4e-42 145.5 0.0 1.8e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAP65470.1 - 5.6e-07 28.8 0.0 2.6e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 OAP65470.1 - 0.00025 20.1 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAP65470.1 - 0.0084 15.4 0.1 0.016 14.5 0.1 1.4 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 OAP65470.1 - 0.071 12.8 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.8 OAP65471.1 - 6.6e-75 250.3 0.0 8e-75 250.0 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family SKG6 PF08693.5 OAP65472.1 - 2.2e-05 23.6 0.9 5.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rax2 PF12768.2 OAP65472.1 - 0.00014 21.2 0.1 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Mid2 PF04478.7 OAP65472.1 - 0.0034 16.8 1.0 0.0034 16.8 0.7 2.6 2 1 0 2 2 2 1 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 OAP65472.1 - 0.019 13.2 0.0 0.033 12.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 OAP65472.1 - 0.029 14.0 0.0 0.055 13.0 0.0 1.4 2 0 0 2 2 2 0 Rifin/stevor family SCF PF02404.10 OAP65472.1 - 0.2 10.7 1.2 0.3 10.2 0.8 1.2 1 0 0 1 1 1 0 Stem cell factor VSP PF03302.8 OAP65472.1 - 1.6 7.2 9.1 0.5 8.9 4.3 1.4 1 1 0 1 1 1 0 Giardia variant-specific surface protein Plasmodium_Vir PF05795.6 OAP65472.1 - 3.2 6.8 3.7 3.4 6.7 0.1 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Med13_C PF06333.7 OAP65472.1 - 6 5.2 7.6 8.5 4.7 5.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal zf-H2C2 PF09337.5 OAP65473.1 - 2.8e-21 74.6 4.7 4.5e-21 73.9 3.3 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 OAP65473.1 - 1.3e-05 25.1 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 OAP65473.1 - 0.00066 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAP65473.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PA14 PF07691.7 OAP65473.1 - 0.038 13.6 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 PA14 domain Acetyltransf_7 PF13508.1 OAP65473.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP65473.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAP65473.1 - 0.2 11.4 0.0 0.45 10.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Fungal_trans_2 PF11951.3 OAP65474.1 - 1.9e-20 72.8 0.7 3e-20 72.1 0.5 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.16 OAP65475.1 - 2.6e-86 290.2 0.0 5.8e-86 289.0 0.0 1.5 1 1 0 1 1 1 1 Amidase DAO PF01266.19 OAP65476.1 - 1.8e-37 129.1 1.2 2.3e-37 128.7 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP65476.1 - 4.1e-05 23.5 0.2 0.00018 21.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP65476.1 - 0.00029 20.7 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAP65476.1 - 0.00039 19.5 0.0 0.00092 18.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAP65476.1 - 0.00068 18.5 0.2 0.0014 17.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAP65476.1 - 0.00089 18.2 0.5 0.0018 17.2 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAP65476.1 - 0.00099 19.2 0.0 0.052 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP65476.1 - 0.0034 17.1 0.9 0.021 14.5 0.3 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.10 OAP65476.1 - 0.0055 14.9 0.0 0.0094 14.1 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.22 OAP65476.1 - 0.054 13.8 0.1 0.38 11.1 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP65476.1 - 0.055 12.3 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.11 OAP65477.1 - 1e-28 100.0 24.2 3e-28 98.5 12.2 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP65477.1 - 5.4e-08 31.8 4.9 5.4e-08 31.8 3.4 3.5 4 0 0 4 4 4 2 Sugar (and other) transporter Kelch_2 PF07646.10 OAP65478.1 - 0.0044 16.7 0.2 0.064 13.0 0.0 3.0 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 OAP65478.1 - 0.042 14.0 3.9 46 4.4 0.0 4.2 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 OAP65478.1 - 0.056 13.2 1.6 35 4.2 0.0 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_1 PF01344.20 OAP65478.1 - 0.13 11.7 2.6 3.3 7.3 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 OAP65478.1 - 2 8.4 6.2 11 6.0 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 OAP65479.1 - 3.7e-10 39.5 1.5 2.4e-09 36.9 0.5 2.5 2 0 0 2 2 2 1 Kelch motif Herpes_gE PF02480.11 OAP65479.1 - 2.4e-05 22.7 0.4 3.7e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 OAP65479.1 - 0.0011 17.8 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Kelch_4 PF13418.1 OAP65479.1 - 0.0031 17.2 5.9 0.18 11.5 1.1 2.7 2 0 0 2 2 2 2 Galactose oxidase, central domain Syndecan PF01034.15 OAP65479.1 - 0.0034 17.0 0.2 0.0059 16.2 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.1 OAP65479.1 - 0.0063 16.8 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kelch_3 PF13415.1 OAP65479.1 - 0.08 13.1 0.5 0.08 13.1 0.4 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Shisa PF13908.1 OAP65479.1 - 0.73 9.9 19.3 0.038 14.1 6.1 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Cpn60_TCP1 PF00118.19 OAP65481.1 - 3.1e-143 477.9 2.8 3.6e-143 477.7 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 OAP65481.1 - 0.04 13.7 0.1 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Peptidase_C14 PF00656.17 OAP65482.1 - 1e-71 241.5 0.0 1.3e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 OAP65482.1 - 0.22 11.3 0.1 0.22 11.3 0.0 2.3 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain LRR_6 PF13516.1 OAP65483.1 - 3.7e-05 23.3 2.2 0.26 11.4 0.0 6.0 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.2 OAP65483.1 - 0.0003 20.3 12.1 2.9 7.6 0.0 6.2 5 1 2 7 7 7 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 OAP65483.1 - 0.00032 20.3 1.2 0.00078 19.1 0.8 1.6 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 OAP65483.1 - 0.0063 16.3 3.0 2.8 8.3 0.1 4.9 6 0 0 6 6 6 1 Leucine Rich Repeat NUFIP1 PF10453.4 OAP65483.1 - 0.018 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) LRR_8 PF13855.1 OAP65483.1 - 0.23 11.2 9.6 24 4.7 0.1 5.5 5 1 1 6 6 6 0 Leucine rich repeat F-box PF00646.28 OAP65483.1 - 0.51 10.0 3.8 0.76 9.4 0.3 2.7 3 0 0 3 3 3 0 F-box domain Folliculin PF11704.3 OAP65484.1 - 1.2e-39 135.6 0.0 2.2e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF1999 PF09390.5 OAP65485.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) RNA_polI_A34 PF08208.6 OAP65486.1 - 2e-24 86.3 2.7 2e-24 86.3 1.9 3.6 2 1 2 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 Daxx PF03344.10 OAP65486.1 - 0.0028 16.2 11.2 0.0028 16.2 7.8 2.0 2 1 0 2 2 2 1 Daxx Family NRPS PF08415.5 OAP65486.1 - 0.074 12.8 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Nonribosomal peptide synthase BSP_II PF05432.6 OAP65486.1 - 1 8.5 19.2 0.1 11.8 10.2 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) SHMT PF00464.14 OAP65487.1 - 1.6e-209 695.2 0.0 1.9e-209 695.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 OAP65487.1 - 3.3e-07 29.6 0.0 8.5e-07 28.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAP65487.1 - 0.0054 15.5 0.0 0.008 14.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 OAP65487.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Baculo_DNA_bind PF04786.7 OAP65487.1 - 0.044 12.9 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 ssDNA binding protein Med9 PF07544.8 OAP65488.1 - 4e-15 55.3 0.6 1e-14 53.9 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 PAT1 PF09770.4 OAP65488.1 - 0.019 13.2 27.0 0.021 13.1 18.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spc42p PF11544.3 OAP65488.1 - 0.12 12.2 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 0 Spindle pole body component Spc42p Macoilin PF09726.4 OAP65488.1 - 0.15 10.2 1.2 0.2 9.8 0.8 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1183 PF06682.7 OAP65488.1 - 0.7 9.4 8.2 0.49 9.9 4.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Ndc1_Nup PF09531.5 OAP65488.1 - 2.2 6.6 9.6 2.6 6.3 6.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIH1 PF08190.7 OAP65488.1 - 2.9 7.2 12.4 4.7 6.5 8.6 1.3 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Hid1 PF12722.2 OAP65488.1 - 6 4.4 8.7 7.6 4.0 6.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EthD PF07110.6 OAP65489.1 - 4.8e-22 78.6 0.1 6e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 EthD domain LANC_like PF05147.8 OAP65490.1 - 2.3e-29 102.0 0.0 4.2e-29 101.2 0.0 1.4 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Lipocalin_5 PF13924.1 OAP65491.1 - 3.1e-27 94.9 0.0 3.6e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain adh_short PF00106.20 OAP65492.1 - 1.2e-10 41.5 0.1 2.2e-09 37.4 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65492.1 - 3.5e-08 33.5 0.0 7.2e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HET PF06985.6 OAP65493.1 - 1.6e-20 73.6 0.7 3.5e-20 72.5 0.5 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Collagen PF01391.13 OAP65494.1 - 4.2e-07 29.4 25.0 7.2e-07 28.6 17.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) NUDIX PF00293.23 OAP65494.1 - 9.9e-07 28.4 0.0 2.5e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain DUF908 PF06012.7 OAP65494.1 - 0.72 9.0 2.9 1 8.5 2.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RNase_H2-Ydr279 PF09468.5 OAP65494.1 - 1.4 8.0 20.9 2.2 7.4 14.5 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) LicD PF04991.8 OAP65494.1 - 2.5 8.1 8.7 2.1 8.3 4.4 1.8 2 0 0 2 2 2 0 LicD family GAGA_bind PF06217.7 OAP65494.1 - 5.4 6.9 18.7 9.6 6.0 13.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_11 PF13086.1 OAP65494.1 - 8.6 5.8 10.1 13 5.2 7.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_transf PF09830.4 OAP65495.1 - 4.4e-19 68.0 0.4 8.5e-19 67.1 0.3 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase SIR2_2 PF13289.1 OAP65496.1 - 1.4e-07 31.4 0.0 4.2e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 SIR2-like domain Zn_clus PF00172.13 OAP65497.1 - 1.6e-05 24.7 6.5 2.5e-05 24.0 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UcrQ PF02939.11 OAP65498.1 - 3.9e-30 103.4 0.2 4.6e-30 103.2 0.1 1.1 1 0 0 1 1 1 1 UcrQ family SF3b1 PF08920.5 OAP65499.1 - 3.9e-37 127.5 2.6 4.5e-36 124.0 1.8 2.3 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 OAP65499.1 - 1.2e-14 54.2 5.7 0.011 16.0 0.0 7.5 5 3 2 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 OAP65499.1 - 5.2e-11 42.6 3.2 0.17 12.4 0.0 8.2 7 2 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 OAP65499.1 - 2.2e-10 39.7 11.2 0.29 11.3 0.2 9.3 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 OAP65499.1 - 2.6e-06 27.7 1.3 1 9.8 0.0 5.5 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 OAP65499.1 - 1.5e-05 23.5 2.2 0.0062 14.9 0.1 3.3 2 2 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 OAP65499.1 - 0.0044 16.4 0.5 0.94 8.7 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal NUC173 PF08161.7 OAP65499.1 - 0.0092 15.3 0.8 6.7 6.0 0.0 3.9 5 0 0 5 5 5 1 NUC173 domain Kisspeptin PF15152.1 OAP65499.1 - 0.038 14.6 0.9 0.11 13.2 0.6 1.7 1 0 0 1 1 1 0 Kisspeptin RasGAP PF00616.14 OAP65500.1 - 5.9e-45 153.3 0.0 1.2e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 OAP65500.1 - 0.15 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 C2 domain RF-1 PF00472.15 OAP65502.1 - 1.9e-33 114.6 3.0 3.7e-33 113.7 2.0 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 OAP65502.1 - 1.2e-28 99.1 0.0 4.6e-28 97.2 0.0 1.9 2 0 0 2 2 2 1 PCRF domain zf-CCCH PF00642.19 OAP65502.1 - 5e-11 42.0 11.2 1.1e-05 25.0 1.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MIR PF02815.14 OAP65502.1 - 0.063 12.8 0.1 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 MIR domain UPF0150 PF03681.10 OAP65502.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) zf-CCCH_2 PF14608.1 OAP65502.1 - 0.54 10.3 15.6 1 9.4 2.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type eIF3_N PF09440.5 OAP65503.1 - 7.2e-43 145.9 5.3 9e-43 145.6 2.7 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 OAP65503.1 - 6e-13 49.0 0.0 2.1e-12 47.2 0.0 2.0 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 OAP65503.1 - 0.014 15.1 0.1 0.042 13.6 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 Img2 PF05046.9 OAP65504.1 - 8.1e-19 67.6 0.0 1.3e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) MSA-2c PF12238.3 OAP65504.1 - 0.46 10.1 2.0 0.66 9.5 1.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c ARID PF01388.16 OAP65505.1 - 5.1e-18 64.7 0.0 1.2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3983 PF13137.1 OAP65505.1 - 0.04 13.6 0.2 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) AAA PF00004.24 OAP65506.1 - 3.3e-45 153.4 0.6 1.2e-44 151.7 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAP65506.1 - 4.1e-09 36.2 0.1 1.5e-08 34.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAP65506.1 - 5.4e-08 32.9 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 OAP65506.1 - 4.2e-07 30.1 0.0 1.3e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAP65506.1 - 8.2e-07 29.2 0.6 0.00027 21.0 0.4 2.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 OAP65506.1 - 3.7e-06 26.0 0.0 7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 OAP65506.1 - 0.00021 21.1 0.0 0.00097 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 OAP65506.1 - 0.00052 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAP65506.1 - 0.00055 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 OAP65506.1 - 0.00059 19.5 0.4 0.056 13.0 0.0 3.1 4 0 0 4 4 3 1 NACHT domain AAA_17 PF13207.1 OAP65506.1 - 0.00096 19.9 0.0 0.0051 17.6 0.0 2.2 3 0 0 3 3 1 1 AAA domain RNA_helicase PF00910.17 OAP65506.1 - 0.00096 19.2 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 OAP65506.1 - 0.0013 17.5 0.0 0.0023 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 OAP65506.1 - 0.0015 18.2 0.2 0.0037 16.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 OAP65506.1 - 0.0023 17.6 0.0 0.0074 16.0 0.0 1.9 2 0 0 2 2 1 1 NTPase Zeta_toxin PF06414.7 OAP65506.1 - 0.0033 16.5 0.1 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 OAP65506.1 - 0.0045 16.5 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 OAP65506.1 - 0.0049 16.4 0.4 0.014 14.9 0.0 1.9 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 OAP65506.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 OAP65506.1 - 0.0056 16.2 0.0 0.045 13.3 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 OAP65506.1 - 0.0069 15.5 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 OAP65506.1 - 0.0077 15.9 0.9 0.052 13.2 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 OAP65506.1 - 0.011 15.1 0.4 0.03 13.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.1 OAP65506.1 - 0.013 15.8 0.3 0.84 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 OAP65506.1 - 0.013 15.0 0.2 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 OAP65506.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAP65506.1 - 0.016 14.5 2.3 0.075 12.4 0.1 2.5 2 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 OAP65506.1 - 0.032 14.5 0.0 0.1 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 OAP65506.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 OAP65506.1 - 0.038 13.1 1.1 0.47 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 OAP65506.1 - 0.051 13.0 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 OAP65506.1 - 0.073 13.1 0.1 0.41 10.6 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 OAP65506.1 - 0.11 10.8 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NB-ARC PF00931.17 OAP65506.1 - 0.14 11.0 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 OAP65506.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Aft1_HRA PF11786.3 OAP65507.1 - 2.9e-28 97.9 9.3 2.9e-28 97.9 6.4 3.0 3 0 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.16 OAP65507.1 - 5.5e-12 45.4 6.5 9.5e-12 44.7 4.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 OAP65507.1 - 5.8e-12 45.9 9.1 5.8e-12 45.9 6.3 3.4 2 1 1 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRR PF11787.3 OAP65507.1 - 6.3e-12 46.3 9.0 6.3e-12 46.3 6.2 4.9 3 2 1 4 4 4 1 Aft1 HRR domain bZIP_2 PF07716.10 OAP65507.1 - 4.6e-07 29.5 5.5 8.9e-07 28.6 3.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 OAP65507.1 - 0.0015 18.7 4.4 0.0037 17.5 3.1 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor TPD52 PF04201.10 OAP65507.1 - 0.056 13.1 1.9 0.066 12.9 0.1 2.1 2 1 0 2 2 2 0 Tumour protein D52 family DivIC PF04977.10 OAP65507.1 - 0.2 11.1 1.0 0.38 10.2 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Spt5_N PF11942.3 OAP65507.1 - 0.21 12.2 7.8 0.41 11.2 5.4 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nop53 PF07767.6 OAP65507.1 - 1.1 8.2 17.0 0.035 13.1 7.6 1.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Ank_2 PF12796.2 OAP65508.1 - 2.6e-20 72.5 0.7 2.6e-10 40.4 0.5 4.1 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP65508.1 - 3.6e-11 43.2 3.5 0.002 18.5 0.0 6.1 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 OAP65508.1 - 1e-10 40.8 9.3 0.004 16.8 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 OAP65508.1 - 6e-07 29.0 2.0 0.062 13.5 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 OAP65508.1 - 0.016 15.4 4.4 0.64 10.3 0.1 4.7 6 1 1 7 7 7 0 Ankyrin repeats (many copies) Pyridoxal_deC PF00282.14 OAP65509.1 - 3e-75 252.9 0.0 1.8e-64 217.5 0.0 2.7 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAP65509.1 - 5.3e-05 22.5 0.0 0.00011 21.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 OAP65509.1 - 0.0025 16.5 0.0 0.0037 16.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V PUF PF00806.14 OAP65510.1 - 5.6e-11 41.2 0.0 0.13 11.7 0.0 7.4 9 0 0 9 9 9 4 Pumilio-family RNA binding repeat Prefoldin_2 PF01920.15 OAP65511.1 - 3.5e-21 74.9 11.6 4.1e-21 74.7 8.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 OAP65511.1 - 0.00042 20.0 3.9 0.00057 19.6 2.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 OAP65511.1 - 0.028 14.2 13.9 0.13 12.1 3.5 2.1 2 0 0 2 2 2 0 Tropomyosin like NPV_P10 PF05531.7 OAP65511.1 - 0.044 14.0 8.8 0.1 12.8 1.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TcdA_TcdB PF12919.2 OAP65511.1 - 0.057 11.9 2.1 0.079 11.4 1.4 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Phage_GP20 PF06810.6 OAP65511.1 - 0.071 12.5 11.6 0.18 11.2 0.9 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Ded_cyto PF06920.8 OAP65511.1 - 0.085 12.1 6.2 0.25 10.6 1.4 2.0 2 0 0 2 2 2 0 Dedicator of cytokinesis DUF4201 PF13870.1 OAP65511.1 - 0.14 11.5 10.5 0.94 8.8 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) IncA PF04156.9 OAP65511.1 - 0.2 11.2 15.5 0.7 9.4 10.7 1.8 1 1 0 1 1 1 0 IncA protein DUF641 PF04859.7 OAP65511.1 - 0.25 11.0 9.3 1.9 8.2 0.6 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 OAP65511.1 - 0.35 11.2 7.8 3.2 8.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF848 PF05852.6 OAP65511.1 - 0.38 10.5 9.4 1.4 8.7 1.8 2.0 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Fib_alpha PF08702.5 OAP65511.1 - 0.38 10.8 9.0 1.4 9.0 6.2 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.12 OAP65511.1 - 0.46 10.1 12.3 0.56 9.8 1.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit TPR_20 PF14561.1 OAP65511.1 - 0.58 10.3 7.3 0.26 11.4 3.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_MLP1_2 PF07926.7 OAP65511.1 - 1.1 8.9 11.5 0.56 9.9 2.4 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 OAP65511.1 - 1.4 8.6 11.3 0.87 9.2 1.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PspA_IM30 PF04012.7 OAP65511.1 - 1.4 8.2 13.3 1.8 7.8 9.2 1.1 1 0 0 1 1 1 0 PspA/IM30 family Occludin_ELL PF07303.8 OAP65511.1 - 1.8 9.3 8.0 6.6 7.5 1.6 2.1 1 1 0 2 2 2 0 Occludin homology domain Sas10_Utp3 PF04000.10 OAP65511.1 - 1.8 8.8 5.9 6.3 7.0 1.1 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family CENP-F_leu_zip PF10473.4 OAP65511.1 - 1.9 8.3 13.8 0.6 9.9 2.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mnd1 PF03962.10 OAP65511.1 - 2.6 7.6 13.7 4.6 6.8 3.2 2.1 1 1 1 2 2 2 0 Mnd1 family GAS PF13851.1 OAP65511.1 - 3.3 6.8 11.6 1.9 7.6 2.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 OAP65511.1 - 3.8 5.8 7.1 6.6 5.0 4.9 1.4 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.7 OAP65511.1 - 5.3 6.8 6.1 17 5.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Dzip-like_N PF13815.1 OAP65511.1 - 6.6 6.5 10.5 8.1 6.2 2.7 2.1 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal COG2 PF06148.6 OAP65511.1 - 9.1 6.1 8.9 1.7 8.4 1.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA PF00004.24 OAP65512.1 - 3.3e-42 143.8 0.0 5.6e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 OAP65512.1 - 6.3e-30 102.8 0.0 3.7e-29 100.4 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 OAP65512.1 - 1.3e-20 73.0 2.9 4.2e-20 71.4 1.6 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 OAP65512.1 - 1.9e-06 28.6 0.0 1e-05 26.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAP65512.1 - 1.3e-05 24.3 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 OAP65512.1 - 1.4e-05 25.2 0.1 0.0013 18.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAP65512.1 - 1.5e-05 24.7 0.0 8.8e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 OAP65512.1 - 3.1e-05 23.4 0.0 5.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAP65512.1 - 3.5e-05 22.7 0.0 5.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 OAP65512.1 - 5.1e-05 23.3 0.0 0.0092 16.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 OAP65512.1 - 5.6e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAP65512.1 - 8.4e-05 22.0 0.8 0.15 11.4 0.1 3.4 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 OAP65512.1 - 0.00017 21.6 0.0 0.0018 18.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 OAP65512.1 - 0.00045 19.2 0.0 0.0011 17.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 OAP65512.1 - 0.00049 19.9 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 OAP65512.1 - 0.00055 19.8 0.0 0.0062 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 OAP65512.1 - 0.0041 16.7 0.0 0.031 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAP65512.1 - 0.006 16.8 0.1 0.018 15.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain Torsin PF06309.6 OAP65512.1 - 0.015 15.1 0.0 0.07 13.0 0.0 1.9 2 0 0 2 2 2 0 Torsin Arch_ATPase PF01637.13 OAP65512.1 - 0.018 14.7 0.2 0.21 11.2 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 OAP65512.1 - 0.02 14.0 0.0 0.062 12.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 OAP65512.1 - 0.021 13.9 0.0 6.4 5.8 0.0 3.1 2 1 1 3 3 3 0 KaiC AAA_19 PF13245.1 OAP65512.1 - 0.023 14.4 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 OAP65512.1 - 0.027 14.1 0.0 0.63 9.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 OAP65512.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 OAP65512.1 - 0.035 13.1 1.5 0.16 11.0 0.0 2.6 2 1 1 3 3 3 0 Zeta toxin Parvo_NS1 PF01057.12 OAP65512.1 - 0.037 12.9 0.0 0.08 11.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 OAP65512.1 - 0.045 12.9 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Peptidase_M28 PF04389.12 OAP65512.1 - 0.048 13.3 0.0 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M28 CPT PF07931.7 OAP65512.1 - 0.065 12.8 0.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 OAP65512.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain XFP_N PF09364.5 OAP65513.1 - 2.6e-174 579.1 0.0 3.5e-174 578.7 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 OAP65513.1 - 6.2e-87 290.2 0.0 8.5e-87 289.8 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 OAP65513.1 - 1.2e-82 275.8 0.0 2.5e-82 274.8 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase COesterase PF00135.23 OAP65515.1 - 2.9e-75 254.0 0.0 3.7e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAP65515.1 - 1.9e-08 34.1 0.1 7.4e-08 32.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP65515.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP65515.1 - 0.088 12.0 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family ELYS PF13934.1 OAP65516.1 - 2.3e-57 194.3 0.2 2.8e-57 194.0 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly Epimerase PF01370.16 OAP65517.1 - 9.1e-05 22.0 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAP65517.1 - 0.00012 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAP65517.1 - 0.0097 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65517.1 - 0.057 13.0 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 KR domain COG7 PF10191.4 OAP65518.1 - 0.22 9.4 0.0 0.3 8.9 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) F-box-like_2 PF13013.1 OAP65519.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain p450 PF00067.17 OAP65520.1 - 5.7e-63 213.0 0.0 7.7e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 OAP65521.1 - 2.1e-23 83.4 0.0 3.8e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP65521.1 - 4.4e-16 58.1 0.1 3.5e-15 55.2 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP65521.1 - 5.6e-10 39.0 0.0 2.3e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP65521.1 - 1.3e-07 30.9 0.0 4.8e-06 25.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP65521.1 - 5.4e-07 29.6 0.0 2e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP65521.1 - 4.8e-06 26.4 0.0 0.00032 20.5 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAP65521.1 - 0.02 13.9 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_4 PF07993.7 OAP65522.1 - 9.7e-45 152.4 0.0 1.5e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 OAP65522.1 - 3.3e-32 111.3 0.2 1e-31 109.8 0.2 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 OAP65522.1 - 2e-11 43.7 0.0 3.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 OAP65522.1 - 2.9e-09 37.0 0.0 9.3e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 OAP65522.1 - 0.00038 20.5 0.0 0.46 10.4 0.0 2.5 2 0 0 2 2 2 2 NADH(P)-binding 3Beta_HSD PF01073.14 OAP65522.1 - 0.00098 17.9 0.0 0.0046 15.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 OAP65522.1 - 0.021 15.1 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 OAP65522.1 - 0.029 14.0 0.1 0.097 12.3 0.1 1.9 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 OAP65522.1 - 0.032 14.1 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAP65522.1 - 0.055 12.3 0.0 0.29 10.0 0.0 2.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein AMP-binding_C PF13193.1 OAP65522.1 - 0.075 13.9 0.2 2.5 9.1 0.0 3.2 4 0 0 4 4 3 0 AMP-binding enzyme C-terminal domain NmrA PF05368.8 OAP65522.1 - 0.17 11.1 0.0 0.38 9.9 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family DXP_reductoisom PF02670.11 OAP65522.1 - 0.17 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Fungal_trans PF04082.13 OAP65523.1 - 3.6e-28 98.1 0.4 6.3e-28 97.3 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP65523.1 - 0.0032 17.3 9.5 0.0061 16.4 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hex_IIIa PF02455.11 OAP65523.1 - 0.025 13.2 0.2 0.043 12.4 0.2 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Nucleoplasmin PF03066.10 OAP65523.1 - 0.51 9.8 7.8 0.88 9.0 0.9 2.3 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 OAP65523.1 - 1.5 9.0 9.3 1.7 8.8 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) HET PF06985.6 OAP65524.1 - 2.1e-33 115.4 0.2 3.8e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TRP PF06011.7 OAP65525.1 - 2.9e-154 513.8 34.7 3.6e-154 513.5 24.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 OAP65525.1 - 1.2e-40 138.7 0.5 2.4e-40 137.8 0.3 1.5 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 OAP65525.1 - 0.033 13.5 2.0 0.42 9.8 0.0 2.7 3 0 0 3 3 3 0 Glycoprotein UL132 zf-PHD-like PF15446.1 OAP65526.1 - 2.1e-74 248.5 10.9 2.1e-74 248.5 7.6 1.8 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 OAP65526.1 - 2e-55 187.7 1.0 3.4e-55 186.9 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAP65526.1 - 1.3e-14 53.8 0.0 2.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 OAP65526.1 - 2.2e-07 30.0 0.9 4.9e-07 28.8 0.6 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 OAP65526.1 - 2.2e-05 24.0 1.1 0.29 10.8 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 OAP65526.1 - 0.00026 20.6 2.3 0.00026 20.6 1.6 4.1 3 2 0 3 3 3 1 PHD-finger DEAD PF00270.24 OAP65526.1 - 0.0049 16.3 0.0 0.02 14.4 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase PHD_2 PF13831.1 OAP65526.1 - 0.91 8.8 14.5 0.062 12.6 2.3 3.8 3 1 0 3 3 3 0 PHD-finger SpoU_methylase PF00588.14 OAP65527.1 - 1.8e-24 86.1 0.0 3e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 OAP65527.1 - 0.00073 19.6 0.0 0.0095 16.0 0.0 2.4 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding MCLC PF05934.6 OAP65527.1 - 0.16 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Ammonium_transp PF00909.16 OAP65529.1 - 2.2e-66 223.9 27.1 3.8e-34 117.8 7.3 2.4 2 1 0 2 2 2 2 Ammonium Transporter Family Patatin PF01734.17 OAP65530.1 - 1.1e-26 93.9 1.2 3.9e-26 92.2 0.8 2.0 1 0 0 1 1 1 1 Patatin-like phospholipase Benyvirus_P25 PF05744.6 OAP65530.1 - 0.0018 17.6 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Benyvirus P25/P26 protein DUF258 PF03193.11 OAP65530.1 - 0.0027 16.9 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 OAP65530.1 - 0.0029 17.5 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 OAP65530.1 - 0.0052 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 OAP65530.1 - 0.0068 15.9 1.2 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF1032 PF06278.6 OAP65530.1 - 0.007 14.8 0.0 0.025 13.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1032) zf-C3HC4 PF00097.20 OAP65530.1 - 0.0073 15.9 5.0 0.021 14.4 3.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_21 PF13304.1 OAP65530.1 - 0.023 14.6 0.6 0.054 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAP65530.1 - 0.028 14.4 0.0 0.099 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain zf-C3HC4_2 PF13923.1 OAP65530.1 - 0.041 13.9 7.8 0.053 13.5 4.4 2.1 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAP65530.1 - 0.047 13.5 5.5 0.19 11.6 3.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING SMC_N PF02463.14 OAP65530.1 - 0.053 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 OAP65530.1 - 0.062 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAP65530.1 - 0.26 10.9 0.1 0.55 9.9 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-RING_2 PF13639.1 OAP65530.1 - 0.51 10.1 11.9 0.12 12.2 4.9 2.4 2 0 0 2 2 2 0 Ring finger domain Fig1 PF12351.3 OAP65531.1 - 2.9e-58 196.7 6.7 2.9e-58 196.7 4.7 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 OAP65531.1 - 5.6e-08 32.6 7.3 1.1e-07 31.6 5.1 1.5 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 OAP65531.1 - 0.0027 16.6 7.6 0.0027 16.6 5.3 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF4013 PF13197.1 OAP65531.1 - 0.21 10.9 19.3 0.16 11.2 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) DUF202 PF02656.10 OAP65531.1 - 4.6 7.5 11.1 2 8.7 0.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) XPG_I PF00867.13 OAP65532.1 - 3.5e-23 81.4 0.0 8.1e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 OAP65532.1 - 6.4e-23 80.9 0.0 1.5e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 OAP65532.1 - 0.00038 20.0 0.0 0.0009 18.8 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing DUF2962 PF11176.3 OAP65533.1 - 2.6e-42 144.0 4.1 2.9e-42 143.8 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Birna_VP3 PF01767.11 OAP65533.1 - 1.1 8.8 5.1 0.23 11.0 0.7 1.8 1 1 1 2 2 2 0 Birnavirus VP3 protein HTH_32 PF13565.1 OAP65533.1 - 1.1 10.0 6.3 3.5 8.4 0.8 2.4 2 0 0 2 2 2 0 Homeodomain-like domain MAM33 PF02330.11 OAP65534.1 - 5.8e-34 117.6 2.1 2.4e-26 92.8 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein p450 PF00067.17 OAP65535.1 - 2e-54 184.8 0.0 5.8e-54 183.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Bacteriocin_IIc PF10439.4 OAP65537.1 - 0.036 14.1 1.2 0.07 13.2 0.8 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide ComC PF03047.9 OAP65537.1 - 0.05 13.0 0.7 0.08 12.3 0.5 1.3 1 0 0 1 1 1 0 COMC family MARVEL PF01284.18 OAP65537.1 - 0.066 13.0 0.1 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF4006 PF13179.1 OAP65537.1 - 4.4 6.9 5.8 9.5 5.8 1.3 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF4006) ATP-grasp_4 PF13535.1 OAP65538.1 - 1.1e-13 51.3 0.0 1.6e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAP65538.1 - 9.4e-10 38.2 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 OAP65538.1 - 0.00015 20.6 0.0 0.00061 18.6 0.0 1.9 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 OAP65538.1 - 0.00067 19.5 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_TupA PF14305.1 OAP65538.1 - 0.0031 16.8 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 TupA-like ATPgrasp CPSase_L_D2 PF02786.12 OAP65538.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.6 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.1 OAP65538.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp FA_desaturase PF00487.19 OAP65539.1 - 6.7e-35 120.7 27.6 9.8e-35 120.2 19.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 OAP65539.1 - 4.4e-09 36.0 0.0 1.3e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Rad51 PF08423.6 OAP65540.1 - 2.4e-09 36.5 0.0 6e-07 28.6 0.0 2.3 2 1 0 2 2 2 2 Rad51 AAA_25 PF13481.1 OAP65540.1 - 6.1e-06 25.7 0.0 3e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAP65540.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 OAP65540.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Dynamin family Mitochondr_Som1 PF11093.3 OAP65541.1 - 9.2e-12 44.6 0.1 1.7e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.4 OAP65542.1 - 4.5e-15 55.4 0.5 2.2e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term RNA_pol_Rpb1_5 PF04998.12 OAP65543.1 - 1.4e-80 270.5 0.0 3e-80 269.4 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 OAP65543.1 - 4.1e-71 239.9 0.0 6.7e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 OAP65543.1 - 3.8e-69 231.9 0.1 8.1e-69 230.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 OAP65543.1 - 9e-38 129.4 0.0 2.5e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 OAP65543.1 - 1.1e-25 89.4 0.0 3.8e-25 87.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 HORMA PF02301.13 OAP65544.1 - 7.2e-48 162.8 0.2 8.4e-48 162.6 0.2 1.0 1 0 0 1 1 1 1 HORMA domain Alba PF01918.16 OAP65544.1 - 0.056 13.0 0.5 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Alba GTP_EFTU PF00009.22 OAP65545.1 - 1.3e-47 161.7 0.0 2.2e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 OAP65545.1 - 1.4e-37 127.8 5.3 2.3e-37 127.2 3.7 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 OAP65545.1 - 8.4e-21 73.6 0.0 1.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAP65545.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 OAP65545.1 - 5.6e-05 22.5 0.0 0.00019 20.8 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 OAP65545.1 - 6.2e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 OAP65545.1 - 0.0024 17.6 0.0 0.0071 16.1 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 OAP65545.1 - 0.0063 15.7 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF998 PF06197.8 OAP65546.1 - 3.8 6.7 13.7 0.043 13.1 1.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF998) SMC_N PF02463.14 OAP65547.1 - 4.3e-79 264.8 0.0 8.5e-79 263.8 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAP65547.1 - 4.3e-27 94.4 0.0 1.4e-26 92.8 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAP65547.1 - 1.2e-11 45.1 7.4 1.1e-05 25.5 0.3 3.7 2 1 1 3 3 3 2 AAA domain HrpB7 PF09486.5 OAP65547.1 - 4.9e-06 26.5 10.6 4.9e-06 26.5 7.4 6.8 4 3 2 7 7 7 3 Bacterial type III secretion protein (HrpB7) AAA_29 PF13555.1 OAP65547.1 - 0.00013 21.4 0.0 0.0003 20.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 OAP65547.1 - 0.00018 21.1 13.4 0.00018 21.1 9.3 7.6 3 2 4 7 7 7 3 IncA protein AAA_13 PF13166.1 OAP65547.1 - 0.0039 15.7 103.8 0.099 11.0 15.1 5.8 3 2 2 6 6 6 2 AAA domain Reo_sigmaC PF04582.7 OAP65547.1 - 0.29 10.2 42.8 0.018 14.2 3.3 6.0 3 2 5 8 8 8 0 Reovirus sigma C capsid protein CRCB PF02537.10 OAP65547.1 - 0.47 10.3 0.1 0.98 9.3 0.1 1.4 1 0 0 1 1 1 0 CrcB-like protein DUF2163 PF09931.4 OAP65547.1 - 5.5 6.7 8.8 0.35 10.6 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2163) Fungal_trans_2 PF11951.3 OAP65548.1 - 0.0055 15.3 0.8 0.98 7.9 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF3196 PF11428.3 OAP65548.1 - 0.15 11.3 0.1 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) MFS_1 PF07690.11 OAP65549.1 - 7.6e-37 126.8 31.0 1.1e-36 126.2 21.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP65549.1 - 8.5e-17 60.8 28.2 1.1e-16 60.4 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.11 OAP65549.1 - 5.3 6.5 14.7 0.29 10.6 5.1 2.5 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 ADH_zinc_N PF00107.21 OAP65550.1 - 3e-26 91.4 0.0 4.6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP65550.1 - 2.1e-14 54.4 0.0 4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP65550.1 - 2.7e-08 33.5 0.0 5.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 OAP65550.1 - 0.062 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PEP_mutase PF13714.1 OAP65551.1 - 1.2e-47 162.1 0.4 1.4e-47 161.9 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 OAP65551.1 - 1.5e-17 63.0 0.4 2.1e-17 62.5 0.3 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 OAP65551.1 - 0.036 13.1 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Coronavirus_5 PF05528.6 OAP65551.1 - 0.13 12.1 0.0 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Coronavirus gene 5 protein P-mevalo_kinase PF04275.9 OAP65551.1 - 0.15 11.7 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Phosphomevalonate kinase DIOX_N PF14226.1 OAP65553.1 - 7e-17 62.0 0.0 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAP65553.1 - 1.4e-09 38.1 0.0 3.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4473 PF14747.1 OAP65553.1 - 0.045 13.9 0.1 8.3 6.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) MmgE_PrpD PF03972.9 OAP65554.1 - 1.3e-25 89.5 0.0 1.5e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family NMT1 PF09084.6 OAP65556.1 - 1.5e-08 34.4 0.1 2.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 OAP65556.1 - 0.011 15.1 0.1 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 NMT1-like family OpuAC PF04069.7 OAP65556.1 - 0.035 13.4 1.0 0.041 13.2 0.1 1.6 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system HTH_DeoR PF08220.7 OAP65556.1 - 0.15 11.5 0.0 5.1 6.7 0.0 2.6 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain Cortexin PF11057.3 OAP65557.1 - 0.049 13.2 0.5 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Cortexin of kidney adh_short PF00106.20 OAP65558.1 - 1e-25 90.5 0.1 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65558.1 - 2.4e-15 56.9 0.0 3e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65558.1 - 2e-07 30.8 0.1 6.6e-07 29.1 0.0 1.8 1 1 1 2 2 2 1 KR domain Pyr_redox_3 PF13738.1 OAP65559.1 - 2.6e-20 73.3 0.0 4e-19 69.4 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP65559.1 - 1.6e-10 39.8 0.0 1e-09 37.1 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP65559.1 - 6.4e-09 35.7 0.2 2.5e-08 33.8 0.1 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP65559.1 - 1.1e-06 27.8 0.0 1.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 OAP65559.1 - 0.0001 21.3 0.6 0.0015 17.5 0.0 2.8 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAP65559.1 - 0.00023 20.1 1.5 0.0055 15.6 0.9 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP65559.1 - 0.00026 20.9 0.0 0.00062 19.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAP65559.1 - 0.00049 19.2 0.3 0.0016 17.5 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 OAP65559.1 - 0.0007 19.7 0.3 0.069 13.2 0.0 3.2 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 OAP65559.1 - 0.0013 17.7 0.1 0.072 11.9 0.0 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAP65559.1 - 0.012 15.3 0.3 0.12 12.1 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 OAP65559.1 - 0.013 14.5 0.6 0.095 11.7 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAP65559.1 - 0.027 12.9 0.3 0.046 12.1 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 OAP65559.1 - 0.062 12.4 0.0 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 OAP65559.1 - 0.078 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 OAP65559.1 - 0.15 10.9 0.0 2.5 6.8 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Sugar_tr PF00083.19 OAP65560.1 - 3.4e-77 259.9 29.5 3.9e-77 259.7 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65560.1 - 1.9e-30 105.7 61.1 9.2e-24 83.8 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 OAP65560.1 - 0.045 13.7 4.7 0.049 13.6 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Pyr_redox_3 PF13738.1 OAP65561.1 - 4.6e-25 88.8 0.0 7.3e-24 84.9 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP65561.1 - 4.7e-07 29.7 0.2 1.8e-06 27.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 OAP65561.1 - 3.4e-05 23.9 0.2 0.0015 18.6 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 OAP65561.1 - 0.00016 20.0 0.0 0.00049 18.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 OAP65561.1 - 0.00066 19.4 1.2 0.034 13.9 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAP65561.1 - 0.0042 16.9 0.8 4.7 7.0 0.0 3.5 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAP65561.1 - 0.0096 14.8 0.0 0.12 11.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AOX PF01786.12 OAP65562.1 - 1.6e-88 295.4 0.1 1.9e-88 295.2 0.1 1.0 1 0 0 1 1 1 1 Alternative oxidase 2OG-FeII_Oxy PF03171.15 OAP65563.1 - 3e-21 75.5 0.0 5e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAP65563.1 - 8.6e-18 64.9 0.0 1.4e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sugar_tr PF00083.19 OAP65564.1 - 2.4e-92 309.8 11.5 4.9e-92 308.8 7.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65564.1 - 6.1e-34 117.2 32.2 1.6e-25 89.5 6.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP65564.1 - 3.2e-05 22.5 31.2 0.0098 14.3 1.8 4.0 2 2 2 4 4 4 3 MFS/sugar transport protein Pkinase PF00069.20 OAP65565.1 - 4.8e-75 252.0 0.0 6.8e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP65565.1 - 1e-39 136.2 0.0 1.5e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 OAP65565.1 - 8.2e-17 61.1 0.2 2.7e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 OAP65565.1 - 1.1e-06 27.8 0.0 4.2e-06 25.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 OAP65565.1 - 0.00034 20.0 0.2 0.00066 19.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 OAP65565.1 - 0.0025 16.4 0.2 0.0038 15.8 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 OAP65565.1 - 0.011 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAP65565.1 - 0.039 13.6 0.2 0.6 9.7 0.0 2.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 OAP65565.1 - 0.11 11.7 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF3455 PF11937.3 OAP65566.1 - 6.7e-07 29.4 0.1 0.00029 20.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3455) PRELI PF04707.9 OAP65567.1 - 1.4e-24 86.4 0.0 6.2e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family tRNA-synt_1b PF00579.20 OAP65568.1 - 3.6e-23 82.1 0.0 6.5e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Antimicrobial_1 PF08018.6 OAP65568.1 - 0.083 12.8 0.1 0.083 12.8 0.1 2.1 3 0 0 3 3 3 0 Frog antimicrobial peptide Aminotran_4 PF01063.14 OAP65569.1 - 2.9e-24 85.8 0.1 3.3e-23 82.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class IV Acetyltransf_1 PF00583.19 OAP65570.1 - 1.6e-08 34.4 0.0 3.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAP65570.1 - 3.4e-06 27.1 0.0 1.2e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAP65570.1 - 8.1e-06 25.9 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAP65570.1 - 1.7e-05 24.6 0.0 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 OAP65570.1 - 0.023 13.9 0.0 0.095 11.9 0.0 1.8 2 0 0 2 2 2 0 MOZ/SAS family AA_permease_2 PF13520.1 OAP65572.1 - 6.6e-47 159.9 44.3 8.3e-47 159.6 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP65572.1 - 3.4e-23 81.7 34.9 4.8e-23 81.2 24.2 1.1 1 0 0 1 1 1 1 Amino acid permease Shikimate_DH PF01488.15 OAP65573.1 - 9.8e-15 54.8 0.0 1.5e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 OAP65573.1 - 2.6e-12 46.6 0.0 5.4e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain ThiF PF00899.16 OAP65573.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 ThiF family YoaP PF14268.1 OAP65573.1 - 0.077 12.2 0.3 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 YoaP-like AlaDh_PNT_C PF01262.16 OAP65573.1 - 0.093 12.2 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AP_endonuc_2 PF01261.19 OAP65574.1 - 4.2e-26 91.5 0.1 7.1e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel TPR_11 PF13414.1 OAP65575.1 - 7.9e-57 188.8 44.5 6.7e-16 57.7 0.4 8.0 4 2 5 10 10 10 9 TPR repeat TPR_1 PF00515.23 OAP65575.1 - 2e-43 144.2 38.8 2.4e-06 26.8 0.1 11.6 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 OAP65575.1 - 5.4e-39 128.9 36.0 2.2e-05 24.0 0.1 11.8 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.1 OAP65575.1 - 7.2e-26 90.2 20.1 9.2e-07 29.3 0.4 6.8 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAP65575.1 - 6.3e-25 86.9 29.2 1.3e-07 31.4 0.1 7.5 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 OAP65575.1 - 9.8e-22 75.3 16.6 0.0072 16.4 0.0 9.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 OAP65575.1 - 8e-20 69.0 31.6 0.028 14.1 0.0 11.5 11 1 1 12 12 11 6 Tetratricopeptide repeat TPR_7 PF13176.1 OAP65575.1 - 1.7e-17 61.7 21.9 0.023 14.4 0.2 9.8 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAP65575.1 - 9.7e-15 53.7 24.4 0.069 13.8 0.2 10.3 3 3 8 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 OAP65575.1 - 2.1e-13 50.4 27.1 5.5e-06 26.6 0.7 7.3 4 2 3 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 OAP65575.1 - 2.1e-12 47.0 20.9 0.00075 19.5 0.2 5.5 3 1 2 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 OAP65575.1 - 7.1e-12 45.0 15.9 0.00015 21.5 0.4 6.8 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 OAP65575.1 - 0.00043 20.5 27.2 3.2 8.4 0.3 9.5 9 0 0 9 9 9 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 OAP65575.1 - 0.00054 19.1 13.3 2.9 7.2 0.1 6.9 7 0 0 7 7 7 1 SHNi-TPR BLVR PF06375.6 OAP65575.1 - 0.0011 18.8 1.4 0.0025 17.6 1.0 1.6 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) TPR_10 PF13374.1 OAP65575.1 - 0.022 14.6 11.5 2.4 8.2 0.2 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.3 OAP65575.1 - 0.034 12.9 21.8 0.091 11.5 0.4 4.8 2 1 2 5 5 5 0 NMDA receptor-regulated protein 1 Pex26 PF07163.7 OAP65575.1 - 0.17 10.8 1.0 1.1 8.0 0.0 2.2 1 1 1 2 2 2 0 Pex26 protein TPR_20 PF14561.1 OAP65575.1 - 0.33 11.1 10.4 0.37 10.9 0.1 4.6 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 OAP65575.1 - 8.2 6.3 18.8 9.6 6.1 0.4 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat FHA PF00498.21 OAP65576.1 - 5.2e-12 45.7 0.0 9.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Podoplanin PF05808.6 OAP65576.1 - 0.18 11.3 3.0 0.094 12.2 0.4 1.8 2 0 0 2 2 2 0 Podoplanin 2OG-FeII_Oxy_2 PF13532.1 OAP65577.1 - 1.3e-25 90.3 1.4 1.4e-25 90.2 0.1 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 OAP65577.1 - 1.2e-23 83.9 0.0 2.6e-22 79.5 0.0 2.5 1 1 0 1 1 1 1 Isochorismatase family Acyl-CoA_dh_1 PF00441.19 OAP65578.1 - 4.9e-22 78.6 1.1 8e-22 77.9 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAP65578.1 - 9.2e-16 58.4 0.3 2.1e-15 57.2 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAP65578.1 - 6.3e-07 28.8 0.2 2.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAP65578.1 - 0.0013 18.9 0.2 0.0013 18.9 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_76 PF03663.9 OAP65579.1 - 9.1e-124 413.5 16.4 1.1e-123 413.3 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 OAP65579.1 - 0.038 13.0 0.3 0.038 13.0 0.2 2.3 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Fungal_trans_2 PF11951.3 OAP65580.1 - 7.9e-07 28.0 0.6 0.00093 17.9 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Z1 PF10593.4 OAP65580.1 - 0.058 12.6 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Z1 domain His_Phos_1 PF00300.17 OAP65581.1 - 4e-15 56.2 0.0 7.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Excalibur PF05901.6 OAP65581.1 - 0.23 11.8 0.2 0.23 11.8 0.1 1.9 2 0 0 2 2 2 0 Excalibur calcium-binding domain DUF3595 PF12166.3 OAP65584.1 - 0.0015 17.4 0.2 0.0018 17.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) Abhydrolase_6 PF12697.2 OAP65587.1 - 6e-29 101.5 0.5 7.6e-29 101.2 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP65587.1 - 7.6e-13 48.5 0.1 1.5e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAP65587.1 - 4.9e-11 42.5 0.1 2.5e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAP65587.1 - 2.8e-07 29.9 0.1 4.7e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 OAP65587.1 - 8.9e-07 28.4 0.0 0.00017 20.9 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.8 OAP65587.1 - 0.00021 20.9 0.1 0.014 15.0 0.0 2.5 3 0 0 3 3 3 1 PGAP1-like protein FSH1 PF03959.8 OAP65587.1 - 0.00038 19.9 0.0 0.0022 17.4 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 OAP65587.1 - 0.0021 17.9 0.0 0.0099 15.7 0.0 2.0 2 1 1 3 3 3 1 TAP-like protein Peptidase_S15 PF02129.13 OAP65587.1 - 0.0023 17.4 0.0 0.0065 15.9 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 OAP65587.1 - 0.0062 16.2 0.0 0.011 15.3 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PhoPQ_related PF10142.4 OAP65587.1 - 0.018 13.5 0.0 0.038 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Thioesterase PF00975.15 OAP65587.1 - 0.042 14.0 0.8 0.17 12.1 0.5 2.1 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 OAP65587.1 - 0.088 12.2 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF915 PF06028.6 OAP65587.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MBF1 PF08523.5 OAP65589.1 - 9.1e-25 86.4 0.6 9.1e-25 86.4 0.4 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 OAP65589.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 OAP65589.1 - 0.0018 18.4 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 OAP65589.1 - 0.041 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Iso_dh PF00180.15 OAP65590.1 - 8.1e-74 248.6 0.0 9.4e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SH3_1 PF00018.23 OAP65591.1 - 1e-15 56.8 0.0 2.5e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 OAP65591.1 - 1.3e-13 50.2 0.0 2.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAP65591.1 - 7e-11 41.4 0.0 1.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PLRV_ORF5 PF01690.12 OAP65591.1 - 0.58 9.2 2.9 0.7 8.9 2.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MRP-S28 PF10213.4 OAP65593.1 - 5.6e-46 155.7 0.1 9.4e-46 155.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.11 OAP65594.1 - 5.3e-16 58.7 0.0 1.4e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 OAP65594.1 - 0.0016 17.7 0.0 0.0023 17.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.13 OAP65594.1 - 0.027 13.0 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase CDC45 PF02724.9 OAP65596.1 - 0.1 10.5 13.6 0.13 10.2 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BORG_CEP PF14957.1 OAP65596.1 - 0.29 12.0 1.7 0.56 11.1 1.2 1.5 1 0 0 1 1 1 0 Cdc42 effector DUF1510 PF07423.6 OAP65596.1 - 0.3 10.4 9.1 0.43 9.9 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Borrelia_P83 PF05262.6 OAP65596.1 - 0.34 9.1 10.5 0.38 8.9 7.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Sec62 PF03839.11 OAP65596.1 - 0.84 9.0 7.9 1.2 8.5 5.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ycf1 PF05758.7 OAP65596.1 - 1 6.9 5.4 1.1 6.8 3.7 1.0 1 0 0 1 1 1 0 Ycf1 Presenilin PF01080.12 OAP65596.1 - 1.4 7.6 3.5 1.7 7.3 2.4 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.2 OAP65596.1 - 1.6 6.2 5.4 1.9 6.0 3.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 OAP65596.1 - 3.1 7.6 8.6 4.8 6.9 5.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2058 PF09831.4 OAP65596.1 - 7.9 6.3 19.0 12 5.7 13.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DOR PF14839.1 OAP65596.1 - 7.9 6.1 12.3 12 5.6 8.5 1.2 1 0 0 1 1 1 0 DOR family zf-U1 PF06220.7 OAP65597.1 - 2.4e-06 26.9 1.0 3.2e-06 26.5 0.7 1.2 1 0 0 1 1 1 1 U1 zinc finger Actin PF00022.14 OAP65598.1 - 9.6e-132 439.1 0.0 1.1e-131 438.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAP65598.1 - 0.024 13.2 0.0 0.35 9.4 0.0 2.3 1 1 0 1 1 1 0 MreB/Mbl protein DUF3602 PF12223.3 OAP65599.1 - 1e-17 64.2 10.6 1.1e-13 51.3 0.3 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Adap_comp_sub PF00928.16 OAP65600.1 - 1.3e-52 178.5 0.0 4e-52 176.9 0.0 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAP65600.1 - 0.00044 19.9 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4188 PF13826.1 OAP65601.1 - 1.1e-29 102.8 0.2 1.7e-29 102.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) ABM PF03992.11 OAP65601.1 - 0.00058 19.8 0.3 0.00095 19.1 0.2 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.1 OAP65601.1 - 0.025 13.6 0.6 0.037 13.0 0.4 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase DUF4267 PF14087.1 OAP65602.1 - 0.00059 19.4 0.5 0.0029 17.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4267) SNF2_N PF00176.18 OAP65603.1 - 4.2e-82 275.2 0.1 8.6e-82 274.2 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 OAP65603.1 - 2.2e-46 156.4 1.3 2.2e-46 156.4 0.9 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 OAP65603.1 - 5.3e-35 120.2 2.1 5.3e-35 120.2 1.5 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 OAP65603.1 - 1.2e-15 57.1 0.0 6.7e-15 54.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAP65603.1 - 1.8e-08 34.4 0.1 5.1e-07 29.7 0.0 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAP65603.1 - 1.4e-05 24.6 0.0 3.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 OAP65603.1 - 0.029 13.7 0.1 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 DUF4588 PF15251.1 OAP65604.1 - 0.0047 16.9 10.1 0.015 15.3 7.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SpoIIIAH PF12685.2 OAP65604.1 - 6.6 6.1 8.7 11 5.4 6.0 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein DAO PF01266.19 OAP65606.1 - 4.2e-44 150.9 0.0 5e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP65606.1 - 8.9e-06 25.6 0.1 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAP65606.1 - 4.6e-05 22.4 0.1 0.00079 18.3 0.0 2.7 3 1 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 OAP65606.1 - 4.8e-05 23.3 0.0 0.0014 18.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP65606.1 - 8.8e-05 22.6 0.0 0.0028 17.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP65606.1 - 0.001 18.8 0.0 0.021 14.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 OAP65606.1 - 0.0043 16.1 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAP65606.1 - 0.033 13.2 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 OAP65606.1 - 0.034 12.6 0.0 0.43 8.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.16 OAP65606.1 - 0.036 13.9 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 ThiF family GMC_oxred_N PF00732.14 OAP65606.1 - 0.037 13.1 0.0 0.61 9.1 0.0 2.4 2 1 0 2 2 2 0 GMC oxidoreductase UDPG_MGDP_dh_N PF03721.9 OAP65606.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 OAP65606.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 OAP65606.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 OAP65606.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Ldh_2 PF02615.9 OAP65606.1 - 0.11 11.1 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase TrkA_N PF02254.13 OAP65606.1 - 0.18 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.1 OAP65606.1 - 0.18 10.6 0.0 0.37 9.6 0.0 1.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 OAP65607.1 - 6.7e-53 178.4 0.0 1e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAP65607.1 - 6.4e-17 61.2 0.0 7.7e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAP65607.1 - 0.0006 19.6 0.0 0.0016 18.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.21 OAP65608.1 - 1.6e-26 92.3 3.7 2.4e-25 88.5 2.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAP65608.1 - 7.8e-23 80.3 0.6 1.6e-22 79.3 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 OAP65608.1 - 0.0006 20.7 2.5 0.0006 20.7 1.7 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 OAP65608.1 - 0.0024 18.4 0.3 0.0058 17.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain F_bP_aldolase PF01116.15 OAP65608.1 - 0.017 14.2 0.5 0.024 13.7 0.4 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II ESX-1_EspG PF14011.1 OAP65608.1 - 0.073 12.3 4.6 0.1 11.8 0.9 2.1 1 1 0 2 2 2 0 EspG family PAN_1 PF00024.21 OAP65609.1 - 1.4 8.7 8.9 0.13 12.0 2.2 2.3 2 0 0 2 2 2 0 PAN domain Fungal_trans PF04082.13 OAP65610.1 - 4.6e-24 84.7 0.0 1.2e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAP65610.1 - 8.3e-09 35.2 11.8 1.3e-08 34.5 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 OAP65611.1 - 2e-71 240.9 27.6 3.4e-71 240.1 14.6 1.9 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAP65611.1 - 7.1e-16 57.8 48.9 8.2e-11 41.2 7.0 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAP65611.1 - 0.0037 17.0 0.2 0.0037 17.0 0.1 2.5 2 1 0 2 2 2 1 MFS_1 like family DUF3021 PF11457.3 OAP65611.1 - 0.52 10.1 12.3 0.36 10.7 5.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) adh_short PF00106.20 OAP65612.1 - 1.2e-30 106.6 1.5 1.5e-30 106.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65612.1 - 2.3e-20 73.3 0.1 2.8e-20 73.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65612.1 - 7.3e-15 55.0 1.0 1.1e-14 54.5 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP65612.1 - 9.8e-05 21.8 0.6 0.00019 20.9 0.4 1.4 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAP65612.1 - 0.00059 19.5 0.2 0.0015 18.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 OAP65612.1 - 0.021 13.8 0.4 0.043 12.8 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 OAP65612.1 - 0.027 14.4 0.3 0.085 12.8 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding Glyco_transf_5 PF08323.6 OAP65612.1 - 0.046 13.2 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain ApbA PF02558.11 OAP65612.1 - 0.075 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_trans_4_4 PF13579.1 OAP65612.1 - 0.091 12.9 0.0 2.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain ACT_7 PF13840.1 OAP65612.1 - 0.14 11.6 1.0 1.2 8.7 0.1 2.8 3 0 0 3 3 3 0 ACT domain ADH_zinc_N PF00107.21 OAP65613.1 - 2.9e-17 62.4 0.2 1.8e-16 59.9 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 OAP65613.1 - 1.2e-05 24.3 3.1 1.4e-05 24.1 1.7 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 OAP65613.1 - 0.0014 18.7 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP65613.1 - 0.0016 16.9 2.3 0.0023 16.4 1.6 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 OAP65613.1 - 0.0044 17.3 0.7 0.026 14.9 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 OAP65613.1 - 0.006 16.4 0.7 0.0097 15.7 0.0 1.6 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 OAP65613.1 - 0.022 14.8 0.3 0.36 10.9 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 OAP65613.1 - 0.036 13.9 0.2 0.066 13.0 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_2 PF07992.9 OAP65613.1 - 0.048 13.5 2.3 0.66 9.8 0.5 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAP65613.1 - 0.049 13.6 1.5 0.11 12.5 1.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 OAP65613.1 - 0.075 12.6 1.0 0.12 12.0 0.7 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 OAP65613.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 OAP65613.1 - 0.12 12.6 0.2 0.24 11.6 0.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_18 PF12847.2 OAP65613.1 - 0.22 12.1 1.2 0.27 11.8 0.8 1.6 1 1 0 1 1 1 0 Methyltransferase domain DAO PF01266.19 OAP65613.1 - 0.28 10.0 3.6 1.6 7.5 1.8 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.20 OAP65614.1 - 1.1e-23 83.9 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65614.1 - 1.6e-12 47.7 0.0 2.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65614.1 - 2.7e-07 30.4 0.0 5.5e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP65614.1 - 6.8e-06 25.6 0.0 1.4e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABM PF03992.11 OAP65615.1 - 1.9e-05 24.5 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Aldo_ket_red PF00248.16 OAP65616.1 - 3.2e-54 183.6 0.0 4e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Shikimate_dh_N PF08501.6 OAP65617.1 - 4.4e-23 81.1 0.0 8.6e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 OAP65617.1 - 3.1e-14 53.2 0.0 4.8e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 OAP65618.1 - 6.2e-18 65.5 0.0 2.8e-17 63.4 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAP65618.1 - 6.2e-13 47.7 0.1 6.5e-11 41.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAP65618.1 - 2.4e-08 33.8 0.0 5.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAP65618.1 - 1.3e-07 30.8 0.1 0.00056 18.9 0.0 3.9 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAP65618.1 - 3e-05 24.0 0.0 0.0028 17.5 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAP65618.1 - 0.00025 20.8 0.0 0.14 11.8 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 OAP65618.1 - 0.086 11.2 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Sugar_tr PF00083.19 OAP65620.1 - 1.4e-91 307.3 22.0 1.6e-91 307.1 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65620.1 - 8.4e-26 90.5 52.7 2.8e-21 75.6 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF912 PF06024.7 OAP65620.1 - 0.89 9.6 2.8 1.6 8.8 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) C2 PF00168.25 OAP65621.1 - 6.7e-14 51.4 0.0 1.3e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain GFO_IDH_MocA PF01408.17 OAP65622.1 - 1.5e-18 67.4 0.7 2.4e-18 66.7 0.5 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAP65622.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 OAP65622.1 - 0.088 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 OAP65622.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain UTP15_C PF09384.5 OAP65623.1 - 3e-42 143.8 0.4 5.3e-42 143.0 0.3 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 OAP65623.1 - 1.6e-25 87.9 0.3 4.3e-08 32.7 0.0 4.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Asp PF00026.18 OAP65624.1 - 3.6e-62 210.4 4.0 4.5e-62 210.1 2.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAP65624.1 - 4.2e-07 30.0 0.0 2.6e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAP65624.1 - 4.5e-05 23.8 0.8 0.35 11.4 0.2 3.3 2 1 0 2 2 2 2 Aspartyl protease Fimbrial_PilY2 PF14481.1 OAP65624.1 - 0.059 12.8 0.3 0.19 11.1 0.2 1.9 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 CAP59_mtransfer PF11735.3 OAP65625.1 - 8.3e-66 221.6 0.0 1.2e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HIT PF01230.18 OAP65626.1 - 4.1e-24 84.9 0.3 6.2e-24 84.3 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAP65626.1 - 6e-15 55.4 0.0 8.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 OAP65626.1 - 0.00045 19.8 0.0 0.0006 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 OAP65626.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Mem_trans PF03547.13 OAP65627.1 - 0.051 11.8 0.7 0.058 11.6 0.5 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF605 PF04652.11 OAP65627.1 - 8.2 5.7 11.1 8.5 5.6 7.7 1.0 1 0 0 1 1 1 0 Vta1 like CRAL_TRIO PF00650.15 OAP65628.1 - 8.3e-45 152.1 0.0 2.1e-44 150.7 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAP65628.1 - 5.4e-17 61.6 0.4 5.3e-16 58.4 0.0 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAP65628.1 - 1.3e-10 41.3 0.0 2.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain NmrA PF05368.8 OAP65630.1 - 3.1e-39 134.6 0.0 3.7e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAP65630.1 - 1.9e-10 41.0 0.2 2.5e-10 40.6 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAP65630.1 - 1.3e-06 27.3 0.0 1.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 OAP65630.1 - 2e-06 27.7 0.0 4.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 OAP65630.1 - 8.3e-06 25.8 0.1 1.1e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65630.1 - 3.9e-05 23.3 0.0 5.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP65630.1 - 4e-05 23.1 0.0 0.0001 21.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 OAP65630.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 OAP65630.1 - 0.015 15.6 0.0 0.034 14.4 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 OAP65630.1 - 0.047 12.6 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 OAP65630.1 - 0.089 13.3 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.7 OAP65630.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein GST_N_3 PF13417.1 OAP65631.1 - 4.6e-09 36.3 0.0 1.4e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAP65631.1 - 1.1e-05 25.3 0.0 0.00035 20.5 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAP65631.1 - 0.0078 16.0 0.0 0.02 14.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain LMWPc PF01451.16 OAP65632.1 - 2.7e-25 89.2 0.0 3.1e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.12 OAP65633.1 - 6.3e-81 269.9 0.1 9.7e-81 269.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAP65633.1 - 6.4e-31 105.8 0.0 1.2e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAP65633.1 - 9.5e-22 77.0 4.1 6e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAP65633.1 - 7.3e-10 38.8 7.1 7.3e-10 38.8 4.9 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAP65633.1 - 1.4e-09 38.0 0.0 3.7e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 MgtE PF01769.11 OAP65633.1 - 0.11 12.7 5.0 6.7 7.0 1.8 2.5 2 0 0 2 2 2 0 Divalent cation transporter MRVI1 PF05781.7 OAP65633.1 - 0.53 8.6 0.0 0.83 7.9 0.0 1.2 1 0 0 1 1 1 0 MRVI1 protein Protocadherin PF08374.6 OAP65633.1 - 1.9 8.0 3.6 4.3 6.9 2.5 1.5 1 0 0 1 1 1 0 Protocadherin UPF0546 PF10639.4 OAP65634.1 - 1.5e-37 127.8 1.4 1.9e-37 127.5 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 DUF2985 PF11204.3 OAP65634.1 - 0.093 12.4 2.7 1.3 8.7 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) EamA PF00892.15 OAP65634.1 - 0.14 12.2 7.0 0.29 11.1 3.1 2.2 2 0 0 2 2 2 0 EamA-like transporter family EmrE PF13536.1 OAP65634.1 - 0.44 10.7 9.3 1.1 9.5 6.5 1.8 1 1 0 1 1 1 0 Multidrug resistance efflux transporter LSR PF05624.9 OAP65634.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Lipolysis stimulated receptor (LSR) Zn_clus PF00172.13 OAP65635.1 - 7.9e-07 28.8 10.3 7.9e-07 28.8 7.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 OAP65635.1 - 2e-05 23.3 0.5 3.7e-05 22.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Macoilin PF09726.4 OAP65636.1 - 0.13 10.4 11.4 0.15 10.3 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 OAP65636.1 - 2.4 7.4 25.0 3.3 7.0 17.3 1.3 1 0 0 1 1 1 0 Vta1 like Sporozoite_P67 PF05642.6 OAP65636.1 - 6.8 4.4 9.5 7.8 4.2 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LAT PF15234.1 OAP65637.1 - 0.15 11.5 0.0 0.15 11.5 0.0 2.3 3 0 0 3 3 3 0 Linker for activation of T-cells BTB PF00651.26 OAP65638.1 - 0.032 14.2 0.5 0.42 10.6 0.0 2.4 3 0 0 3 3 3 0 BTB/POZ domain PhyH PF05721.8 OAP65639.1 - 2.2e-55 187.9 0.0 2.7e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.20 OAP65640.1 - 7e-19 68.3 0.0 1.1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAP65640.1 - 9.6e-09 35.3 0.0 1.3e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAP65640.1 - 2.2e-08 33.9 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP65640.1 - 0.002 17.6 0.0 0.0029 17.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 OAP65640.1 - 0.083 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 OAP65640.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Sulfate_transp PF00916.15 OAP65641.1 - 1e-06 27.9 1.5 1e-06 27.9 1.1 2.6 2 1 1 3 3 3 2 Sulfate transporter family RRM_1 PF00076.17 OAP65642.1 - 1.1e-51 172.3 1.3 7.2e-16 57.5 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP65642.1 - 1.2e-47 159.7 0.3 3.7e-16 58.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP65642.1 - 1.9e-29 101.2 0.1 2.4e-08 33.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAP65642.1 - 1.1e-08 34.7 0.0 0.00032 20.4 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 OAP65642.1 - 0.00012 21.7 1.8 11 5.8 0.1 4.7 4 0 0 4 4 4 1 Limkain b1 DUF1866 PF08952.6 OAP65642.1 - 0.023 14.2 0.0 6.3 6.3 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1866) Lsm_interact PF05391.6 OAP65642.1 - 0.074 12.5 0.1 0.23 10.9 0.1 1.9 1 0 0 1 1 1 0 Lsm interaction motif Ribosomal_L22 PF00237.14 OAP65643.1 - 3.4e-16 59.0 0.0 6.9e-07 29.1 0.1 2.6 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e p450 PF00067.17 OAP65644.1 - 8.4e-72 242.1 0.0 1.7e-69 234.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 OAP65644.1 - 1.3e-29 103.2 0.8 6.4e-29 100.9 0.3 2.2 2 1 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 OAP65644.1 - 2.4e-21 76.2 0.0 4.8e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAP65644.1 - 1e-12 48.5 0.0 2.7e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 OAP65644.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Peptidase_C39_2 PF13529.1 OAP65644.1 - 0.053 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Peptidase_C39 like family Claudin_2 PF13903.1 OAP65645.1 - 0.0039 16.9 5.0 0.0052 16.4 3.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4013 PF13197.1 OAP65645.1 - 0.018 14.3 2.0 0.024 13.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Oxidored_q2 PF00420.19 OAP65645.1 - 0.031 13.8 0.7 0.031 13.8 0.5 1.9 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2637 PF10935.3 OAP65645.1 - 0.23 11.3 4.0 0.22 11.4 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) FecCD PF01032.13 OAP65645.1 - 0.32 9.7 4.4 0.37 9.5 3.0 1.1 1 0 0 1 1 1 0 FecCD transport family DUF4305 PF14146.1 OAP65645.1 - 0.77 9.5 0.1 0.77 9.5 0.1 2.6 3 2 1 4 4 4 0 Domain of unknown function (DUF4305) DUF998 PF06197.8 OAP65645.1 - 1.1 8.5 7.9 2.2 7.5 5.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) FAD_binding_3 PF01494.14 OAP65646.1 - 9.2e-47 159.7 0.0 1.4e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 OAP65646.1 - 4.9e-08 32.2 0.1 0.0021 17.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAP65646.1 - 4.6e-05 23.3 0.5 0.00013 21.9 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAP65646.1 - 4.8e-05 22.0 0.1 0.00049 18.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 OAP65646.1 - 0.00024 20.2 0.5 0.00085 18.4 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 OAP65646.1 - 0.00058 20.2 0.1 0.036 14.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAP65646.1 - 0.0014 17.6 0.2 0.0086 15.0 0.1 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAP65646.1 - 0.0021 17.8 0.5 2.4 7.9 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 OAP65646.1 - 0.0022 17.1 0.9 0.45 9.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP65646.1 - 0.0045 16.8 0.1 0.018 14.9 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP65646.1 - 0.016 15.2 0.1 0.046 13.7 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAP65646.1 - 0.017 14.0 1.1 0.036 12.9 0.8 1.5 1 1 1 2 2 2 0 FAD binding domain SE PF08491.5 OAP65646.1 - 0.14 10.9 0.0 4 6.1 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 OAP65646.1 - 0.4 9.2 5.7 2.8 6.4 0.6 2.8 3 0 0 3 3 3 0 Tryptophan halogenase p450 PF00067.17 OAP65647.1 - 1.4e-58 198.6 0.0 1.8e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Soyouz_module PF14313.1 OAP65647.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Glyco_hydro_30 PF02055.11 OAP65648.1 - 4.1e-16 58.2 1.2 4.7e-15 54.7 0.8 2.2 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 OAP65648.1 - 0.0088 15.8 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_hydr_30_2 PF14587.1 OAP65648.1 - 0.013 14.4 0.5 0.023 13.6 0.0 1.6 2 0 0 2 2 2 0 O-Glycosyl hydrolase family 30 Cu_amine_oxid PF01179.15 OAP65649.1 - 1e-160 535.0 0.0 1.2e-160 534.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 OAP65649.1 - 5.6e-08 32.7 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 OAP65649.1 - 9.4e-08 32.0 0.1 2e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.1 OAP65650.1 - 1.1e-61 208.6 48.3 1.4e-61 208.3 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAP65650.1 - 7.2e-22 77.3 41.5 9.8e-22 76.9 28.8 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 OAP65652.1 - 3.4e-80 269.8 19.6 4.2e-80 269.5 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65652.1 - 2.6e-15 55.9 41.1 8.1e-12 44.5 5.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP65652.1 - 0.00018 20.0 2.8 0.00018 20.0 1.9 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein Peptidase_S8 PF00082.17 OAP65653.1 - 8.3e-54 182.6 11.9 1.3e-53 182.0 8.2 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 OAP65653.1 - 2.3e-18 66.5 0.5 5.4e-18 65.3 0.1 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 GST_N PF02798.15 OAP65655.1 - 2.3e-13 50.0 0.0 5.6e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAP65655.1 - 1.4e-11 44.4 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAP65655.1 - 4.6e-08 32.9 0.0 7.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAP65655.1 - 5.7e-08 32.6 0.2 2.8e-07 30.4 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAP65655.1 - 2.8e-05 24.4 0.1 4.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAP65655.1 - 0.0039 17.0 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Beach PF02138.13 OAP65656.1 - 1.5e-107 359.1 0.0 2.7e-107 358.2 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 OAP65656.1 - 5.7e-11 42.2 0.0 1.6e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 OAP65656.1 - 2.6e-10 39.7 1.0 2.3e-05 24.0 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 OAP65656.1 - 1e-08 35.5 0.0 2.9e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily eIF-5a PF01287.15 OAP65656.1 - 2.5e-06 27.3 0.1 4.2e-05 23.3 0.0 2.8 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Glyco_transf_54 PF04666.8 OAP65657.1 - 4.8e-11 41.9 0.0 3.8e-09 35.7 0.0 2.8 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region LicD PF04991.8 OAP65659.1 - 1.7e-35 123.0 1.9 3.3e-34 118.8 1.3 2.1 1 1 0 1 1 1 1 LicD family Isochorismatase PF00857.15 OAP65660.1 - 9.2e-39 133.1 0.0 1.1e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family SRR1 PF07985.7 OAP65661.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 SRR1 RRP7 PF12923.2 OAP65661.1 - 0.037 14.0 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) adh_short PF00106.20 OAP65662.1 - 1.9e-12 47.4 0.4 3.1e-12 46.7 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65662.1 - 2e-05 24.3 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAP65662.1 - 0.00014 21.7 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAP65662.1 - 0.00071 19.0 0.2 0.0015 18.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_12 PF13087.1 OAP65664.1 - 6.2e-37 126.9 0.0 1.3e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAP65664.1 - 3.4e-22 79.1 0.1 2.8e-21 76.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAP65664.1 - 8.5e-10 38.2 0.0 2.6e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAP65664.1 - 1.6e-08 34.3 0.0 1e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 OAP65664.1 - 3.7e-06 26.6 0.0 0.019 14.5 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 OAP65664.1 - 0.0028 17.5 0.2 0.0085 15.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 OAP65664.1 - 0.0062 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 OAP65664.1 - 0.0075 16.2 0.0 0.022 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.24 OAP65664.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.9 OAP65664.1 - 0.035 13.8 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 OAP65664.1 - 0.063 12.2 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 OAP65664.1 - 0.14 12.3 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 OAP65665.1 - 7.1e-18 63.7 7.8 0.00082 19.1 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Glyco_hydro_17 PF00332.13 OAP65667.1 - 7e-10 38.4 1.5 4.1e-07 29.3 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Ycf1 PF05758.7 OAP65668.1 - 0.029 12.1 11.8 0.051 11.3 8.2 1.3 1 0 0 1 1 1 0 Ycf1 NARP1 PF12569.3 OAP65668.1 - 0.47 9.1 15.6 0.74 8.4 10.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mem_trans PF03547.13 OAP65668.1 - 1.8 6.7 3.4 2.6 6.2 2.3 1.2 1 0 0 1 1 1 0 Membrane transport protein LMBR1 PF04791.11 OAP65668.1 - 3 6.3 5.4 4.2 5.8 3.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FLO_LFY PF01698.11 OAP65668.1 - 3.5 6.3 18.5 6.4 5.5 12.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 OAP65668.1 - 9.6 6.4 25.2 21 5.3 17.5 1.5 1 0 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 OAP65670.1 - 2.4e-29 101.9 8.0 2.4e-29 101.9 5.5 2.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 OAP65670.1 - 0.0056 16.1 0.1 0.0056 16.1 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4131) DUF4117 PF13491.1 OAP65670.1 - 2.3 7.6 9.0 5.9 6.3 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) Transaldolase PF00923.14 OAP65671.1 - 8.9e-97 323.6 0.0 1e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Abhydrolase_6 PF12697.2 OAP65673.1 - 3.4e-30 105.6 2.6 2.8e-29 102.6 1.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP65673.1 - 1.6e-12 47.3 0.0 6.7e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP65673.1 - 6e-09 35.7 0.4 2.3e-08 33.9 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAP65673.1 - 6.4e-08 32.3 0.0 1.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 OAP65673.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase GXGXG PF01493.14 OAP65673.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 GXGXG motif UQ_con PF00179.21 OAP65674.1 - 3.8e-40 136.5 0.0 5e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAP65674.1 - 0.052 13.4 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 RWD domain ABC_tran PF00005.22 OAP65675.1 - 8.6e-54 181.5 0.2 3.8e-30 104.9 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAP65675.1 - 5.3e-51 173.6 21.7 8e-28 97.6 2.8 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 OAP65675.1 - 1e-08 35.5 1.1 0.054 13.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 OAP65675.1 - 7.6e-08 31.8 2.1 0.0093 15.2 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAP65675.1 - 1.2e-07 32.2 0.2 0.00022 21.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 OAP65675.1 - 3.7e-06 26.5 0.1 0.0069 15.8 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 OAP65675.1 - 5.4e-06 25.9 0.4 0.13 11.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 OAP65675.1 - 1.5e-05 25.1 0.2 1.1 9.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 OAP65675.1 - 3.4e-05 23.0 0.0 0.046 12.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 OAP65675.1 - 5.1e-05 22.4 0.6 0.019 14.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.18 OAP65675.1 - 0.00028 20.8 0.1 0.18 11.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 OAP65675.1 - 0.00067 20.1 0.0 2 8.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 OAP65675.1 - 0.00068 19.6 0.9 2.5 8.0 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 OAP65675.1 - 0.0007 18.5 0.1 0.055 12.3 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 OAP65675.1 - 0.0014 18.1 5.1 0.48 9.9 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 OAP65675.1 - 0.0018 19.0 0.0 2.7 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 OAP65675.1 - 0.003 17.0 0.1 1.6 8.1 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF87 PF01935.12 OAP65675.1 - 0.01 15.6 4.0 0.022 14.6 0.1 2.8 2 1 1 3 3 2 0 Domain of unknown function DUF87 MobB PF03205.9 OAP65675.1 - 0.022 14.4 0.1 14 5.3 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 OAP65675.1 - 0.025 14.8 2.2 6 7.1 0.1 3.2 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 OAP65675.1 - 0.025 14.0 0.0 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 OAP65675.1 - 0.039 13.5 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 OAP65675.1 - 0.053 13.7 0.7 6.8 6.8 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 OAP65675.1 - 0.063 12.7 0.1 8.2 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 OAP65675.1 - 0.087 11.8 0.0 0.23 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 OAP65675.1 - 0.093 12.5 0.0 21 4.8 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit cobW PF02492.14 OAP65675.1 - 0.13 11.6 1.0 0.95 8.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 OAP65675.1 - 0.14 11.7 0.0 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase Dynamin_N PF00350.18 OAP65675.1 - 0.15 11.8 0.9 8.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family UPF0079 PF02367.12 OAP65675.1 - 0.16 11.6 2.0 4.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Abhydrolase_6 PF12697.2 OAP65676.1 - 1.2e-21 77.6 0.0 1e-20 74.6 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP65676.1 - 6e-13 48.7 0.5 1.1e-11 44.6 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAP65676.1 - 1.5e-07 31.2 0.0 0.0051 16.3 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold SAP PF02037.22 OAP65678.1 - 1.5e-07 30.7 0.1 2.7e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 SAP domain RRM_1 PF00076.17 OAP65678.1 - 0.079 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.13 OAP65679.1 - 1.8e-31 108.3 0.2 4.1e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.22 OAP65680.1 - 2.7e-38 131.2 0.0 4.6e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 OAP65680.1 - 7.8e-25 86.5 0.1 1.7e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 OAP65680.1 - 6.2e-17 61.2 0.0 2.8e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAP65680.1 - 3.4e-07 30.2 0.0 1.3e-06 28.4 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 OAP65680.1 - 0.0011 18.5 0.0 0.026 14.0 0.0 2.6 2 1 1 3 3 3 1 Elongation factor G, domain IV Vps5 PF09325.5 OAP65681.1 - 4.4e-12 45.7 4.9 7.4e-12 45.0 3.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 OAP65681.1 - 1.8e-09 37.3 0.0 3.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.1 OAP65681.1 - 0.027 14.4 0.4 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NTR2 PF15458.1 OAP65682.1 - 0.00034 19.9 0.6 0.00056 19.2 0.4 1.3 1 0 0 1 1 1 1 Nineteen complex-related protein 2 HOOK PF05622.7 OAP65682.1 - 0.0036 15.2 0.1 0.0048 14.7 0.0 1.1 1 0 0 1 1 1 1 HOOK protein zf-C4H2 PF10146.4 OAP65682.1 - 0.0041 17.1 0.3 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Zinc finger-containing protein CCDC155 PF14662.1 OAP65682.1 - 0.0048 16.5 3.9 0.0082 15.7 2.7 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Tektin PF03148.9 OAP65682.1 - 0.0087 14.6 1.2 0.012 14.1 0.8 1.2 1 0 0 1 1 1 1 Tektin family DUF2353 PF09789.4 OAP65682.1 - 0.031 13.5 0.3 0.049 12.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) APG6 PF04111.7 OAP65682.1 - 0.039 12.9 0.8 0.059 12.4 0.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 OAP65682.1 - 0.046 13.7 1.7 0.1 12.6 1.2 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Kinesin-relat_1 PF12711.2 OAP65682.1 - 0.13 12.7 5.0 1.6 9.2 1.7 2.8 2 1 0 2 2 2 0 Kinesin motor ADIP PF11559.3 OAP65682.1 - 0.16 11.8 5.0 0.37 10.6 3.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 OAP65682.1 - 0.19 11.0 4.4 0.35 10.2 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) RasGAP_C PF03836.10 OAP65682.1 - 0.32 10.6 2.6 0.69 9.5 1.8 1.5 1 0 0 1 1 1 0 RasGAP C-terminus DUF904 PF06005.7 OAP65682.1 - 0.48 10.7 9.3 2.6 8.3 4.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 OAP65682.1 - 0.49 10.7 3.5 0.72 10.2 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 OAP65682.1 - 0.82 8.8 7.9 0.043 12.9 1.2 2.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4172 PF13776.1 OAP65682.1 - 0.94 9.6 4.1 11 6.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) DivIC PF04977.10 OAP65682.1 - 2.7 7.5 8.7 0.33 10.4 2.4 2.1 2 1 0 2 2 2 0 Septum formation initiator GFA PF04828.9 OAP65683.1 - 7.5e-14 51.4 0.1 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DiS_P_DiS PF06750.8 OAP65683.1 - 0.055 13.2 1.1 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Epimerase PF01370.16 OAP65685.1 - 2.5e-09 36.9 0.0 0.00023 20.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 OAP65685.1 - 3e-07 30.7 0.0 2.1e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 OAP65685.1 - 0.0036 16.2 0.0 0.011 14.6 0.0 1.9 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.8 OAP65685.1 - 0.0038 16.5 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 OAP65685.1 - 0.0083 14.8 0.0 0.9 8.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Tho2 PF11262.3 OAP65686.1 - 2.2e-84 283.0 0.0 3.3e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 OAP65686.1 - 2.2e-25 88.2 0.0 7e-25 86.6 0.0 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Sec23_trunk PF04811.10 OAP65687.1 - 1.2e-56 191.8 0.0 2e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAP65687.1 - 2.8e-23 81.2 0.0 5.8e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAP65687.1 - 6e-18 65.1 0.0 1.1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 OAP65687.1 - 1.3e-15 56.6 4.8 2.5e-15 55.7 3.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 OAP65687.1 - 7e-07 28.8 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat MFS_1 PF07690.11 OAP65688.1 - 7.5e-49 166.3 36.2 1.2e-48 165.6 25.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAP65688.1 - 2.2e-09 36.1 1.1 2.2e-09 36.1 0.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 OAP65688.1 - 0.0083 14.2 3.3 0.0078 14.3 0.9 1.8 1 1 1 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 OAP65688.1 - 1.2 7.1 9.9 0.25 9.3 0.3 3.2 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_1 PF00561.15 OAP65689.1 - 5.7e-49 166.7 0.1 1.2e-47 162.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAP65689.1 - 7.2e-14 52.2 0.2 2.1e-13 50.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAP65689.1 - 0.00023 20.9 0.3 0.0041 16.8 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 OAP65689.1 - 0.071 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Solute_trans_a PF03619.11 OAP65690.1 - 1.8e-83 280.0 29.0 2.1e-83 279.8 20.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2273 PF10031.4 OAP65690.1 - 8.9 6.0 10.4 1.4 8.5 0.4 2.6 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Cu_amine_oxid PF01179.15 OAP65691.1 - 1e-156 521.8 0.0 1.3e-156 521.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 OAP65691.1 - 2.9e-11 43.3 0.0 5.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 OAP65691.1 - 2.3e-07 30.8 0.0 5.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain CPSF100_C PF13299.1 OAP65693.1 - 3.7e-37 128.0 0.0 3.7e-37 128.0 0.0 2.6 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 OAP65693.1 - 1.3e-23 83.2 0.0 3.5e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 OAP65693.1 - 4.8e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 OAP65693.1 - 0.0046 16.6 0.0 0.02 14.5 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Swi5 PF07061.6 OAP65694.1 - 2e-15 56.3 0.1 2e-15 56.3 0.0 2.8 2 1 0 2 2 2 1 Swi5 SPX PF03105.14 OAP65694.1 - 0.24 11.1 12.0 1.5 8.4 8.3 1.9 1 1 0 1 1 1 0 SPX domain DUF848 PF05852.6 OAP65694.1 - 0.41 10.4 7.4 0.88 9.4 5.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) SOBP PF15279.1 OAP65694.1 - 3.2 8.0 13.1 4.2 7.6 9.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ribosomal_60s PF00428.14 OAP65694.1 - 3.4 8.1 9.3 1.1 9.6 4.0 2.1 1 1 0 1 1 1 0 60s Acidic ribosomal protein Ndc1_Nup PF09531.5 OAP65694.1 - 5.3 5.3 11.4 7.8 4.7 7.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_UL25 PF01499.11 OAP65694.1 - 5.4 5.2 9.9 6.7 4.9 6.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family TFIIA PF03153.8 OAP65694.1 - 6 6.6 14.3 8.3 6.1 9.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_membrane PF00664.18 OAP65695.1 - 5.7e-86 288.3 35.5 5.3e-46 157.2 13.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAP65695.1 - 9.9e-68 226.6 0.0 1.8e-32 112.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAP65695.1 - 3.4e-13 49.3 0.0 2.6e-05 23.5 0.1 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAP65695.1 - 1.4e-10 41.6 0.5 0.59 10.0 0.0 4.3 2 2 0 4 4 4 4 AAA domain ABC_ATPase PF09818.4 OAP65695.1 - 8.5e-09 34.5 2.5 0.0025 16.4 0.1 3.3 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 OAP65695.1 - 2.3e-08 33.4 1.5 0.00056 19.3 0.2 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 OAP65695.1 - 6.9e-08 33.3 0.0 0.012 16.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAP65695.1 - 4.8e-07 29.9 3.8 0.0035 17.3 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 OAP65695.1 - 1.5e-05 24.2 0.1 0.092 11.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAP65695.1 - 2e-05 24.0 0.8 0.18 11.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.12 OAP65695.1 - 4.3e-05 23.4 0.9 0.029 14.2 0.3 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 OAP65695.1 - 0.00019 21.2 2.1 0.54 10.2 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 OAP65695.1 - 0.00034 20.9 0.0 1.1 9.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 OAP65695.1 - 0.0011 18.8 0.0 0.78 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 OAP65695.1 - 0.0023 17.9 0.1 0.49 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 OAP65695.1 - 0.0034 17.2 0.1 2.6 7.9 0.0 4.0 5 0 0 5 5 4 1 AAA domain AAA_22 PF13401.1 OAP65695.1 - 0.0034 17.5 8.4 2.2 8.4 0.0 5.1 5 1 0 5 5 5 1 AAA domain AAA_10 PF12846.2 OAP65695.1 - 0.0067 15.9 4.6 11 5.3 0.1 4.8 5 0 0 5 5 5 0 AAA-like domain Zeta_toxin PF06414.7 OAP65695.1 - 0.0085 15.2 0.5 7.6 5.5 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin G-alpha PF00503.15 OAP65695.1 - 0.014 14.0 0.1 1.9 7.1 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.9 OAP65695.1 - 0.017 14.8 0.2 12 5.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 OAP65695.1 - 0.034 14.0 0.1 17 5.4 0.0 3.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 OAP65695.1 - 0.04 14.0 0.1 11 6.2 0.0 3.6 3 0 0 3 3 3 0 RNA helicase Katanin_con80 PF13925.1 OAP65695.1 - 0.046 13.4 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 con80 domain of Katanin AAA_23 PF13476.1 OAP65695.1 - 0.052 13.8 0.0 4.3 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 OAP65695.1 - 0.085 12.4 0.2 3.4 7.1 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 OAP65695.1 - 0.088 12.4 0.4 2.5 7.7 0.1 3.0 2 1 1 3 3 3 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 OAP65695.1 - 0.21 11.0 1.7 9.6 5.6 0.1 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family ECH PF00378.15 OAP65696.1 - 4.3e-22 78.4 0.0 5.1e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF500 PF04366.7 OAP65697.1 - 3.6e-40 136.2 0.1 6.6e-40 135.4 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Polysacc_deac_1 PF01522.16 OAP65698.1 - 1.7e-31 108.4 0.0 1.1e-30 105.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Ytp1 PF10355.4 OAP65699.1 - 1.3e-84 283.6 12.7 2e-84 282.9 8.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 OAP65699.1 - 1.4e-30 104.9 0.3 1.4e-30 104.9 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Pex2_Pex12 PF04757.9 OAP65700.1 - 4.4e-40 137.5 3.1 5.9e-40 137.1 2.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 OAP65700.1 - 2.6e-11 43.3 8.8 4.4e-11 42.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAP65700.1 - 5.6e-11 42.0 9.7 9.4e-11 41.3 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAP65700.1 - 1e-10 41.0 6.4 1.5e-10 40.5 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAP65700.1 - 4.7e-10 38.9 7.5 9.1e-10 38.0 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAP65700.1 - 8.5e-10 38.2 7.2 1.3e-09 37.5 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAP65700.1 - 1.6e-06 27.7 1.9 2.1e-06 27.3 0.8 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAP65700.1 - 1.9e-06 27.6 8.5 3.4e-06 26.8 5.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 OAP65700.1 - 3.9e-05 23.6 8.3 0.00012 22.1 5.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 OAP65700.1 - 0.00021 21.0 3.0 0.00041 20.0 2.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 OAP65700.1 - 0.0051 16.6 3.8 0.0095 15.7 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 OAP65700.1 - 0.0056 16.1 3.8 0.01 15.3 2.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 OAP65700.1 - 0.013 15.1 7.8 0.025 14.1 5.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 OAP65700.1 - 0.36 10.7 6.4 0.88 9.5 4.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 OAP65700.1 - 2.1 8.3 9.0 4.3 7.2 5.7 1.9 1 1 0 1 1 1 0 IBR domain DUF3824 PF12868.2 OAP65700.1 - 2.4 9.0 10.3 2.2 9.2 5.5 2.0 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Abhydrolase_3 PF07859.8 OAP65701.1 - 2.1e-38 132.0 0.0 2.8e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAP65701.1 - 5.7e-05 22.0 0.0 0.032 12.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 OAP65701.1 - 0.025 14.3 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 OAP65702.1 - 3.9e-17 62.4 0.0 6.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP65702.1 - 2.8e-09 37.3 0.0 5.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP65702.1 - 2e-08 34.7 0.1 4.6e-07 30.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP65702.1 - 3.6e-08 33.1 0.0 1e-06 28.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP65702.1 - 2.1e-07 31.3 0.0 3.1e-06 27.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP65702.1 - 4e-05 23.9 0.0 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 OAP65702.1 - 0.0033 16.9 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 OAP65702.1 - 0.0058 15.7 0.0 0.26 10.3 0.0 2.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 OAP65702.1 - 0.014 15.4 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 OAP65702.1 - 0.016 15.2 0.1 0.11 12.4 0.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 OAP65702.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 OAP65702.1 - 0.12 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 OAP65703.1 - 4.9e-11 42.6 0.0 1.1e-09 38.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP65703.1 - 3.7e-06 26.5 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP65703.1 - 1.9e-05 25.2 0.0 4.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAP65703.1 - 0.0091 15.3 5.1 2.1 7.6 0.7 3.9 2 1 0 3 3 3 1 Methyltransferase small domain Methyltransf_25 PF13649.1 OAP65703.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 OAP65703.1 - 0.011 14.8 0.5 0.041 12.9 0.6 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.11 OAP65703.1 - 0.044 12.8 0.0 0.36 9.8 0.0 2.2 2 1 0 2 2 2 0 N-6 DNA Methylase UPF0020 PF01170.13 OAP65703.1 - 0.092 12.3 0.0 14 5.1 0.0 2.9 3 0 0 3 3 3 0 Putative RNA methylase family UPF0020 Polysacc_deac_1 PF01522.16 OAP65704.1 - 4e-25 87.8 0.0 7.3e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 OAP65704.1 - 9e-06 25.2 0.0 1.8e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.10 OAP65704.1 - 0.003 16.5 0.0 0.0052 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 CHGN PF05679.11 OAP65705.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.5 1 1 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase COX5A PF02284.11 OAP65706.1 - 9.9e-41 138.0 0.3 1.3e-40 137.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 OAP65706.1 - 0.019 13.3 0.3 0.14 10.5 0.0 1.9 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 DUF488 PF04343.8 OAP65706.1 - 0.5 10.7 2.1 1.3 9.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF488 ELO PF01151.13 OAP65707.1 - 2.1e-63 213.9 22.5 2.4e-63 213.7 15.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GATase_5 PF13507.1 OAP65708.1 - 9.4e-86 286.9 0.0 2e-85 285.8 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 OAP65708.1 - 2e-47 161.0 0.0 8.2e-26 90.8 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 OAP65708.1 - 2.6e-26 91.6 0.9 1.4e-25 89.3 0.0 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Sugar_tr PF00083.19 OAP65709.1 - 7.3e-101 337.9 16.2 8.6e-101 337.7 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65709.1 - 6.6e-32 110.5 48.2 2e-27 95.8 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_18A PF09771.4 OAP65709.1 - 1.5 8.7 5.5 2.3 8.2 0.1 3.0 4 0 0 4 4 4 0 Transmembrane protein 188 Mito_carr PF00153.22 OAP65711.1 - 2.2e-18 65.7 3.3 2.6e-11 43.0 0.0 3.6 3 1 0 3 3 3 2 Mitochondrial carrier protein Self-incomp_S1 PF05938.6 OAP65711.1 - 0.042 13.9 0.1 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 POR_N PF01855.14 OAP65711.1 - 0.57 9.6 3.6 14 5.0 2.0 2.1 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SPT16 PF08644.6 OAP65712.1 - 9.6e-58 194.3 0.1 9.6e-58 194.3 0.1 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 OAP65712.1 - 9.2e-49 165.1 0.3 9.2e-49 165.1 0.2 2.5 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 OAP65712.1 - 7e-26 91.0 0.0 1.4e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 OAP65712.1 - 1.8e-20 72.6 0.0 4.7e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Apolipoprotein PF01442.13 OAP65715.1 - 0.0021 17.6 0.2 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2562 PF10814.3 OAP65715.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2562) SF-assemblin PF06705.6 OAP65715.1 - 0.01 15.0 0.7 0.015 14.4 0.5 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF1640 PF07798.6 OAP65715.1 - 0.014 15.4 1.4 0.02 14.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1664 PF07889.7 OAP65715.1 - 0.019 14.7 0.9 0.031 14.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 OAP65715.1 - 0.021 14.6 0.1 0.061 13.1 0.1 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 OAP65715.1 - 0.034 13.7 0.3 0.054 13.0 0.2 1.4 1 0 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 OAP65715.1 - 0.043 13.8 0.8 0.069 13.1 0.5 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil UPF0242 PF06785.6 OAP65715.1 - 0.053 12.2 0.0 0.061 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Fzo_mitofusin PF04799.8 OAP65715.1 - 0.068 12.5 0.9 0.14 11.5 0.6 1.5 1 1 0 1 1 1 0 fzo-like conserved region DUF4618 PF15397.1 OAP65715.1 - 0.082 12.2 1.2 0.62 9.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) COG2 PF06148.6 OAP65715.1 - 0.12 12.2 2.0 0.22 11.3 1.4 1.4 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.6 OAP65715.1 - 0.13 9.7 0.1 0.16 9.4 0.1 1.1 1 0 0 1 1 1 0 Prominin TMF_DNA_bd PF12329.3 OAP65715.1 - 0.17 11.6 1.2 0.49 10.2 0.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Rootletin PF15035.1 OAP65715.1 - 0.18 11.7 2.3 0.8 9.6 1.6 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Vps51 PF08700.6 OAP65715.1 - 0.24 11.2 1.7 0.46 10.3 1.1 1.5 1 1 0 1 1 1 0 Vps51/Vps67 DUF2730 PF10805.3 OAP65715.1 - 0.29 10.8 2.2 0.29 10.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF776 PF05604.6 OAP65716.1 - 0.12 12.6 1.0 0.23 11.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF776) Tyrosinase PF00264.15 OAP65717.1 - 8.3e-36 124.2 0.1 1.1e-35 123.8 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase SUI1 PF01253.17 OAP65718.1 - 2e-14 53.1 0.0 5.4e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 CENP-T PF15511.1 OAP65718.1 - 0.02 14.1 0.4 0.036 13.3 0.3 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1264 PF06884.6 OAP65719.1 - 2.3e-60 202.9 0.1 2.8e-60 202.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF2767 PF10965.3 OAP65719.1 - 0.012 15.3 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) adh_short_C2 PF13561.1 OAP65720.1 - 1.8e-32 113.0 0.0 2.3e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAP65720.1 - 9.4e-28 97.2 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAP65720.1 - 7.6e-08 32.2 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAP65720.1 - 0.0022 17.4 0.1 0.0066 15.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 OAP65720.1 - 0.03 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 OAP65720.1 - 0.033 13.8 0.1 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 OAP65720.1 - 0.076 11.6 0.1 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Velvet PF11754.3 OAP65721.1 - 1.3e-53 181.6 0.0 2.6e-53 180.6 0.0 1.5 1 1 0 1 1 1 1 Velvet factor His_Phos_2 PF00328.17 OAP65724.1 - 4.2e-08 32.9 0.0 1.2e-05 24.8 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) FAD_binding_2 PF00890.19 OAP65725.1 - 7.8e-121 403.8 5.1 1e-120 403.4 3.5 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 OAP65725.1 - 2e-43 147.3 0.3 3e-43 146.7 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 OAP65725.1 - 1.5e-07 30.6 0.3 2.4e-06 26.7 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAP65725.1 - 7.2e-06 26.0 4.0 0.0026 17.6 0.1 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAP65725.1 - 0.002 16.6 0.6 0.23 9.8 0.2 3.0 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 OAP65725.1 - 0.003 16.7 0.9 0.078 12.0 0.1 2.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 OAP65725.1 - 0.008 15.0 2.2 0.16 10.8 1.9 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAP65725.1 - 0.011 14.7 1.0 0.018 14.1 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain Ribonucleas_3_3 PF14622.1 OAP65726.1 - 1.7e-15 57.1 0.0 5.5e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 OAP65726.1 - 0.11 12.9 0.1 8.8 6.8 0.0 2.6 2 1 1 3 3 3 0 Ribonuclease III domain Adap_comp_sub PF00928.16 OAP65727.1 - 1.7e-91 305.9 0.0 2.4e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAP65727.1 - 3e-09 36.7 0.3 5.1e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ank_2 PF12796.2 OAP65728.1 - 7.5e-28 96.7 1.7 7.8e-15 54.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAP65728.1 - 4.8e-16 58.7 0.5 1.5e-08 34.8 0.1 3.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 OAP65728.1 - 9.2e-16 56.7 0.9 5.8e-12 44.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 OAP65728.1 - 9.3e-15 54.3 0.6 1e-11 44.6 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAP65728.1 - 3.4e-12 45.3 0.4 2e-08 33.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Peptidase_M36 PF02128.10 OAP65728.1 - 0.039 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) p450 PF00067.17 OAP65729.1 - 1.6e-15 56.6 0.0 8.3e-09 34.4 0.0 3.2 2 2 0 2 2 2 2 Cytochrome P450 RNA12 PF10443.4 OAP65730.1 - 6.2e-168 558.7 1.2 8.3e-168 558.3 0.8 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 OAP65730.1 - 4.5e-06 26.5 0.0 3e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 OAP65730.1 - 4.6e-06 26.1 0.0 4.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 OAP65730.1 - 0.021 14.6 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) DBD_Tnp_Hermes PF10683.4 OAP65730.1 - 0.022 14.2 0.1 0.064 12.7 0.0 1.7 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain RRM_6 PF14259.1 OAP65730.1 - 0.066 13.1 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 OAP65730.1 - 0.092 12.7 0.0 0.44 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain DUF3128 PF11326.3 OAP65731.1 - 5.5e-30 103.3 4.1 5.5e-30 103.3 2.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) Methyltransf_23 PF13489.1 OAP65732.1 - 2.4e-14 53.3 0.0 3.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAP65732.1 - 5.5e-13 49.4 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAP65732.1 - 6.7e-13 48.8 0.1 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAP65732.1 - 4.6e-12 46.2 0.0 1.2e-11 44.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAP65732.1 - 1e-11 45.1 0.0 1.8e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAP65732.1 - 3.9e-11 43.0 0.6 1.1e-10 41.5 0.4 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAP65732.1 - 1.2e-10 41.1 0.0 2.4e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAP65732.1 - 2.1e-05 23.7 0.0 3.8e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAP65732.1 - 6.8e-05 22.3 0.0 0.0069 15.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.6 OAP65732.1 - 0.00035 20.0 0.0 0.0037 16.6 0.0 2.0 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.7 OAP65732.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Pox_MCEL PF03291.11 OAP65732.1 - 0.0022 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_9 PF08003.6 OAP65732.1 - 0.0027 16.4 0.0 0.004 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 OAP65732.1 - 0.0032 16.6 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF3321 PF11968.3 OAP65732.1 - 0.006 16.2 0.0 0.012 15.2 0.0 1.4 2 0 0 2 2 2 1 Putative methyltransferase (DUF3321) Methyltransf_32 PF13679.1 OAP65732.1 - 0.043 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 OAP65732.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PCMT PF01135.14 OAP65732.1 - 0.085 12.3 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 OAP65732.1 - 0.12 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GST_N PF02798.15 OAP65733.1 - 5.3e-08 32.9 0.0 2e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAP65733.1 - 5.7e-08 33.1 0.1 1.2e-07 32.0 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAP65733.1 - 2.6e-06 27.3 0.0 1.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAP65733.1 - 1.6e-05 24.7 0.3 2.6e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAP65733.1 - 0.00065 19.8 0.0 0.0028 17.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GMC_oxred_N PF00732.14 OAP65734.1 - 1.4e-65 221.3 0.0 2e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAP65734.1 - 2e-32 112.4 0.0 3.5e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAP65734.1 - 2.1e-07 30.1 0.8 0.00057 18.8 0.2 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAP65734.1 - 9.2e-05 21.5 0.1 0.00016 20.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAP65734.1 - 0.00019 20.4 2.8 0.044 12.6 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 OAP65734.1 - 0.00063 19.7 0.3 0.0021 18.0 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAP65734.1 - 0.0077 16.1 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAP65734.1 - 0.051 13.6 0.2 9 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAP65734.1 - 0.11 12.4 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 OAP65734.1 - 0.22 9.9 0.4 6.2 5.1 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Radical_SAM PF04055.16 OAP65736.1 - 4.8e-10 39.8 0.0 7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 OAP65736.1 - 2.3e-06 27.7 0.0 4.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 OAP65736.1 - 0.00039 20.4 0.1 0.00096 19.1 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain KNTase_C PF07827.6 OAP65736.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 KNTase C-terminal domain DUF92 PF01940.11 OAP65737.1 - 2.3e-59 200.2 10.3 2.8e-59 200.0 7.1 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Asp PF00026.18 OAP65739.1 - 3.7e-14 52.6 0.0 7e-14 51.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAP65739.1 - 0.16 11.5 0.0 1.7 8.1 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal SKG6 PF08693.5 OAP65739.1 - 3.4 7.0 6.3 0.23 10.8 0.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Clathrin PF00637.15 OAP65740.1 - 5.9e-20 71.3 6.3 9.2e-20 70.7 0.3 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 OAP65740.1 - 1.2e-17 63.5 0.2 2.4e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 OAP65740.1 - 0.00042 19.9 6.2 0.0008 19.0 4.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 OAP65740.1 - 0.00048 19.9 5.6 0.00095 18.9 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAP65740.1 - 0.0017 18.3 5.9 0.0033 17.3 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 OAP65740.1 - 0.0037 17.3 1.0 0.0085 16.2 0.7 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-C3HC4 PF00097.20 OAP65740.1 - 0.0077 15.8 7.0 0.015 14.9 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAP65740.1 - 0.0078 16.0 1.5 0.017 14.9 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_11 PF13414.1 OAP65740.1 - 0.0082 15.7 0.2 0.033 13.8 0.0 2.1 2 0 0 2 2 2 1 TPR repeat Vps39_2 PF10367.4 OAP65740.1 - 0.026 14.6 1.0 0.081 13.1 0.7 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPR_14 PF13428.1 OAP65740.1 - 0.034 14.7 0.4 2.4 9.0 0.0 3.9 4 1 1 5 5 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAP65740.1 - 0.037 13.9 1.8 0.14 12.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 OAP65740.1 - 0.064 13.3 3.5 0.13 12.3 2.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 OAP65740.1 - 0.47 10.3 5.7 0.92 9.4 3.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_12 PF13424.1 OAP65740.1 - 0.48 10.3 9.7 0.16 11.9 0.5 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAP65740.1 - 0.67 9.8 4.4 0.73 9.7 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat PHD PF00628.24 OAP65740.1 - 0.76 9.5 4.1 1.6 8.4 2.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 OAP65740.1 - 1.2 8.6 4.1 3.3 7.2 2.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.20 OAP65741.1 - 1.9e-62 210.7 0.0 3.5e-62 209.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAP65741.1 - 1.2e-35 122.9 0.0 2e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 OAP65741.1 - 2.6e-32 110.3 15.0 3.1e-18 65.2 2.7 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 OAP65741.1 - 3.8e-20 71.3 28.7 2.4e-11 43.1 7.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 OAP65741.1 - 6.2e-13 49.0 2.2 2.2e-12 47.3 1.5 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain PAT1 PF09770.4 OAP65741.1 - 0.49 8.5 49.4 1.2 7.2 34.2 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugar_tr PF00083.19 OAP65742.1 - 5.8e-88 295.4 24.7 7.1e-88 295.1 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAP65742.1 - 1.8e-28 99.2 41.3 3.8e-18 65.3 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2_C PF02836.12 OAP65743.1 - 2e-103 345.3 0.0 2.6e-103 345.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 OAP65743.1 - 7.5e-53 179.3 0.0 1.5e-52 178.3 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 OAP65743.1 - 7.9e-51 171.9 0.1 1.7e-50 170.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 OAP65743.1 - 2.5e-15 56.8 0.0 4.8e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 OAP65743.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Fungal_trans PF04082.13 OAP65744.1 - 3e-05 23.0 0.0 6.2e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 OAP65745.1 - 9.9e-66 221.4 0.0 1.1e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cupin_2 PF07883.6 OAP65746.1 - 1.1e-11 44.1 0.0 1.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 OAP65746.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 OAP65746.1 - 0.00062 19.1 0.1 0.001 18.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 OAP65746.1 - 0.0044 16.6 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 Cupin F-box-like PF12937.2 OAP65747.1 - 6.3e-05 22.6 0.2 0.00015 21.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAP65747.1 - 0.02 14.5 0.7 0.041 13.5 0.5 1.6 1 0 0 1 1 1 0 F-box domain Sulfatase PF00884.18 OAP65748.1 - 4e-63 213.4 0.0 5.2e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 OAP65748.1 - 0.0038 15.7 0.0 0.0059 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 OAP65748.1 - 0.0041 16.5 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 OAP65748.1 - 0.15 12.3 0.5 0.98 9.7 0.2 2.3 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase NACHT PF05729.7 OAP65750.1 - 2.8e-09 36.8 0.1 6.8e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 OAP65750.1 - 8.2e-07 29.1 3.5 2.1e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAP65750.1 - 1e-06 28.9 0.8 2.6e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 OAP65750.1 - 0.001 18.0 0.1 0.0056 15.5 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.1 OAP65750.1 - 0.0028 18.4 0.0 0.023 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 OAP65750.1 - 0.0032 17.2 0.0 0.009 15.7 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 OAP65750.1 - 0.0078 16.5 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 OAP65750.1 - 0.012 15.0 2.4 0.34 10.2 0.0 3.3 3 1 1 4 4 4 0 AAA-like domain AAA_29 PF13555.1 OAP65750.1 - 0.017 14.6 0.0 0.086 12.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 OAP65750.1 - 0.065 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAP65750.1 - 0.17 12.0 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase HAMP PF00672.20 OAP65750.1 - 3.2 8.0 8.3 87 3.4 0.0 3.7 2 1 0 2 2 2 0 HAMP domain DUF4410 PF14366.1 OAP65751.1 - 1.7 8.3 4.3 0.31 10.7 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) DUF3500 PF12006.3 OAP65752.1 - 7.4e-104 347.0 0.0 8.7e-104 346.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DUF4185 PF13810.1 OAP65753.1 - 1.8e-13 50.0 3.8 6.3e-13 48.3 1.4 1.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4185) MFS_1 PF07690.11 OAP65754.1 - 2e-20 72.8 46.0 4.1e-12 45.4 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 OAP65754.1 - 2.5e-11 42.6 15.3 6e-07 28.2 0.8 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein DUF872 PF05915.7 OAP65754.1 - 0.3 10.9 5.2 10 6.0 0.0 3.5 3 1 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) eIF-1a PF01176.14 OAP65755.1 - 9.4e-14 50.5 0.0 1.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 OAP65756.1 - 4.9e-122 407.7 10.1 5.6e-122 407.5 7.0 1.0 1 0 0 1 1 1 1 ALG3 protein FMN_dh PF01070.13 OAP65757.1 - 1.5e-127 425.3 0.0 1.8e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 OAP65757.1 - 1.3e-06 27.5 0.2 2.9e-06 26.4 0.1 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 OAP65757.1 - 9.5e-06 24.7 0.0 2.3e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 OAP65757.1 - 4.2e-05 22.8 1.7 8.5e-05 21.8 1.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 OAP65757.1 - 0.00042 19.6 0.0 0.0023 17.2 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 OAP65757.1 - 0.0083 15.2 0.3 0.23 10.4 0.0 2.2 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG PcrB PF01884.12 OAP65757.1 - 0.063 12.5 0.2 9.3 5.4 0.0 2.2 1 1 1 2 2 2 0 PcrB family DHO_dh PF01180.16 OAP65757.1 - 0.17 10.8 0.1 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase zf-C2H2 PF00096.21 OAP65758.1 - 8.6e-08 32.0 32.2 0.066 13.5 0.3 6.1 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 OAP65758.1 - 1.7e-06 27.9 19.1 0.069 13.3 0.2 5.7 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 OAP65758.1 - 2.2e-06 27.5 30.1 0.1 12.9 1.8 6.0 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAP65758.1 - 0.04 13.8 0.0 0.04 13.8 0.0 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 OAP65758.1 - 0.098 12.8 25.3 2.6 8.3 0.1 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAP65758.1 - 2.4 8.3 26.4 20 5.3 0.0 4.5 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) PLDc_2 PF13091.1 OAP65759.1 - 7e-14 51.6 0.0 1.2e-05 25.0 0.0 3.4 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 OAP65759.1 - 5.4e-13 48.2 1.5 1.9e-05 24.2 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Cyanate_lyase PF02560.9 OAP65760.1 - 2.7e-29 100.4 0.0 4.2e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 OAP65760.1 - 0.0027 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 OAP65760.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain 5_3_exonuc PF01367.15 OAP65762.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Hid1 PF12722.2 OAP65762.1 - 4.3 4.9 5.3 4.6 4.7 3.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4094 PF13334.1 OAP65762.1 - 6.3 7.2 6.2 7 7.1 3.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CDC45 PF02724.9 OAP65762.1 - 10 4.0 7.3 12 3.7 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 OAP65763.1 - 2.6e-21 75.0 0.0 2.1e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAP65763.1 - 6.1e-19 67.7 0.0 3.3e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAP65763.1 - 0.011 15.5 0.7 0.26 11.1 0.1 2.8 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Colicin_Ia PF11504.3 OAP65763.1 - 0.11 12.3 1.5 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Colicin Ia AAA PF00004.24 OAP65764.1 - 2.4e-07 30.9 0.1 2e-06 28.0 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAP65764.1 - 0.00026 21.1 0.2 0.0016 18.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAP65764.1 - 0.00062 19.4 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAP65764.1 - 0.00093 19.2 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 OAP65764.1 - 0.0012 19.7 0.0 0.003 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 OAP65764.1 - 0.0075 15.0 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 OAP65764.1 - 0.019 14.5 0.3 0.077 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 OAP65764.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 OAP65764.1 - 0.028 14.7 0.1 0.16 12.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 OAP65764.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 OAP65764.1 - 0.043 12.8 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 OAP65764.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 1 0 NTPase Rad17 PF03215.10 OAP65764.1 - 0.062 11.9 0.0 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 OAP65764.1 - 0.074 12.7 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 OAP65764.1 - 0.087 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SAM_2 PF07647.12 OAP65766.1 - 8.1e-17 60.8 0.0 1.4e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAP65766.1 - 2.6e-13 49.9 0.0 4.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 OAP65766.1 - 6.6e-12 45.7 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain EnY2 PF10163.4 OAP65767.1 - 1.8e-05 24.5 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2795 PF11387.3 OAP65767.1 - 0.019 14.8 0.1 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) AAA PF00004.24 OAP65768.1 - 9.7e-97 320.2 0.1 5.6e-47 159.2 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 OAP65768.1 - 4.7e-20 71.3 0.5 1.3e-19 69.9 0.3 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 OAP65768.1 - 2.9e-14 53.3 0.1 8.8e-08 32.2 0.0 3.1 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 OAP65768.1 - 1.7e-13 50.6 0.0 4.5e-06 26.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 OAP65768.1 - 3e-13 49.3 0.0 1.7e-05 24.0 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 OAP65768.1 - 1.6e-12 47.3 0.4 8.1e-06 25.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAP65768.1 - 1.7e-11 44.4 0.2 0.0018 18.3 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAP65768.1 - 2.3e-11 44.5 0.0 0.00062 20.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAP65768.1 - 4.7e-10 39.7 0.1 0.0022 17.9 0.0 3.9 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 OAP65768.1 - 3e-09 36.0 0.1 0.0011 17.7 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 OAP65768.1 - 3.8e-08 32.9 0.0 0.0052 16.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 OAP65768.1 - 4.6e-08 32.6 5.0 0.015 14.7 0.0 4.6 3 2 2 5 5 4 2 AAA domain Mg_chelatase PF01078.16 OAP65768.1 - 7.7e-08 31.7 0.4 0.0057 15.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 OAP65768.1 - 9.6e-08 31.3 0.0 0.0072 15.4 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin AAA_14 PF13173.1 OAP65768.1 - 1.3e-07 31.5 0.0 0.0072 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 OAP65768.1 - 2.2e-07 30.4 1.3 0.0083 15.8 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain CDC48_2 PF02933.12 OAP65768.1 - 3e-07 29.9 0.0 7.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 OAP65768.1 - 1.5e-06 28.3 0.0 0.024 14.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 OAP65768.1 - 1.8e-06 28.0 0.1 0.09 12.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 OAP65768.1 - 2.4e-06 26.8 1.1 0.68 9.0 0.0 3.6 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 OAP65768.1 - 4e-06 27.1 0.0 0.085 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 OAP65768.1 - 4.7e-06 26.5 0.0 0.005 16.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Vps4_C PF09336.5 OAP65768.1 - 2.4e-05 24.1 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.8 OAP65768.1 - 2.5e-05 23.3 0.0 0.014 14.3 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 OAP65768.1 - 3e-05 23.7 0.2 0.095 12.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 OAP65768.1 - 3.8e-05 23.9 0.0 0.23 11.7 0.0 3.5 2 1 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 OAP65768.1 - 3.9e-05 23.1 0.1 0.44 10.0 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 OAP65768.1 - 4.6e-05 22.4 0.1 0.043 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 OAP65768.1 - 5.1e-05 23.3 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 OAP65768.1 - 7.3e-05 22.5 0.0 2.6 7.6 0.1 4.1 2 2 2 4 4 4 1 Archaeal ATPase NACHT PF05729.7 OAP65768.1 - 8.4e-05 22.2 0.1 0.082 12.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain PhoH PF02562.11 OAP65768.1 - 9.2e-05 21.7 0.3 0.48 9.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Bac_DnaA PF00308.13 OAP65768.1 - 0.00011 21.9 0.0 0.71 9.4 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_3 PF07726.6 OAP65768.1 - 0.00042 19.9 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 OAP65768.1 - 0.00048 19.7 0.0 0.49 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 OAP65768.1 - 0.00056 19.5 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 OAP65768.1 - 0.0013 18.4 0.6 0.65 9.6 0.0 3.9 4 0 0 4 4 3 1 NTPase Viral_helicase1 PF01443.13 OAP65768.1 - 0.0023 17.4 0.0 0.29 10.6 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 OAP65768.1 - 0.0034 16.4 0.0 1.5 7.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 OAP65768.1 - 0.0041 16.0 0.1 0.55 9.0 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_10 PF12846.2 OAP65768.1 - 0.0063 15.9 0.9 1.6 8.0 0.0 3.7 3 1 1 4 4 4 1 AAA-like domain KAP_NTPase PF07693.9 OAP65768.1 - 0.01 14.8 0.0 0.8 8.6 0.0 2.9 2 1 0 3 3 3 0 KAP family P-loop domain IPT PF01745.11 OAP65768.1 - 0.014 14.6 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase T2SE PF00437.15 OAP65768.1 - 0.027 13.3 0.0 2.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein UFD1 PF03152.9 OAP65768.1 - 0.043 12.9 0.0 2.7 7.1 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 KTI12 PF08433.5 OAP65768.1 - 0.086 12.0 0.4 11 5.1 0.0 2.8 3 0 0 3 3 2 0 Chromatin associated protein KTI12 MobB PF03205.9 OAP65768.1 - 0.094 12.4 0.2 3.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 OAP65768.1 - 0.11 12.0 0.1 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zot PF05707.7 OAP65768.1 - 0.18 11.2 0.9 24 4.3 0.0 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) Kei1 PF08552.6 OAP65769.1 - 1.1e-52 178.4 1.6 1.4e-52 178.1 1.1 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ADH_N PF08240.7 OAP65770.1 - 3.7e-27 94.2 0.5 2e-26 91.8 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAP65770.1 - 2e-22 79.1 0.0 3.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAP65770.1 - 0.00039 21.3 0.0 0.0017 19.2 0.0 2.0 2 1 1 3 3 3 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 OAP65770.1 - 0.11 12.8 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 OAP65770.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pantoate_transf PF02548.10 OAP65771.1 - 2.8e-83 279.0 0.5 3.4e-83 278.7 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 OAP65771.1 - 1.3e-06 27.8 2.0 1.1e-05 24.7 1.4 2.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PAP2_3 PF14378.1 OAP65772.1 - 1.4e-19 70.3 9.4 4.5e-10 39.3 0.1 3.6 3 1 0 3 3 3 3 PAP2 superfamily GHMP_kinases_N PF00288.21 OAP65773.1 - 4.4e-16 58.7 2.5 1.1e-15 57.4 1.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAP65773.1 - 1e-07 32.0 0.1 4.3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal Rad60-SLD_2 PF13881.1 OAP65774.1 - 7.1e-10 38.7 0.0 2.3e-09 37.0 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAP65774.1 - 0.0056 16.8 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain SSP160 PF06933.6 OAP65774.1 - 2.5 5.9 5.9 3.1 5.6 4.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UMP1 PF05348.6 OAP65775.1 - 3.5e-23 81.9 0.0 4.5e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF834 PF05754.9 OAP65775.1 - 0.073 12.8 0.4 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF834) PRK PF00485.13 OAP65777.1 - 3.2e-56 189.9 0.0 4.9e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 OAP65777.1 - 8.1e-39 132.9 0.0 1.3e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 OAP65777.1 - 2.6e-09 37.9 0.0 5.3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAP65777.1 - 1.8e-07 31.5 0.0 3.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 OAP65777.1 - 0.00014 21.5 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 OAP65777.1 - 0.0028 16.7 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 OAP65777.1 - 0.0035 17.2 0.0 0.05 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAP65777.1 - 0.029 13.7 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAP65777.1 - 0.039 13.6 0.1 0.36 10.5 0.0 2.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 OAP65777.1 - 0.039 14.1 0.0 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pribosyltran PF00156.22 OAP65777.1 - 0.044 13.5 0.0 0.35 10.5 0.0 2.5 3 0 0 3 3 3 0 Phosphoribosyl transferase domain TIP49 PF06068.8 OAP65777.1 - 0.068 11.8 0.3 0.13 10.9 0.1 1.5 1 1 0 1 1 1 0 TIP49 C-terminus UPF0079 PF02367.12 OAP65777.1 - 0.081 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 OAP65777.1 - 0.086 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 OAP65777.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.15 OAP65777.1 - 0.14 11.8 0.3 2.9 7.5 0.0 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase ABC_tran PF00005.22 OAP65777.1 - 0.15 12.3 0.3 0.76 10.0 0.1 2.1 2 0 0 2 2 2 0 ABC transporter RNase_T PF00929.19 OAP65778.1 - 2.5e-26 92.8 0.0 4.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease RNase_H2_suC PF08615.6 OAP65779.1 - 7.6e-24 84.1 0.0 2.8e-23 82.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4385 PF14328.1 OAP65780.1 - 2.7e-48 163.5 0.6 3.5e-48 163.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) bZIP_1 PF00170.16 OAP65782.1 - 0.0012 18.6 18.9 0.0052 16.7 12.2 2.2 1 1 1 2 2 2 2 bZIP transcription factor DUF848 PF05852.6 OAP65782.1 - 0.0021 17.8 1.1 0.003 17.3 0.8 1.2 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Atg14 PF10186.4 OAP65782.1 - 0.0095 14.9 3.0 0.012 14.5 2.1 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 TSC22 PF01166.13 OAP65782.1 - 0.0097 15.8 1.3 0.022 14.7 0.9 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_Maf PF03131.12 OAP65782.1 - 0.018 15.3 8.7 0.03 14.5 6.0 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TMF_DNA_bd PF12329.3 OAP65782.1 - 0.6 9.9 5.1 1.1 9.0 3.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fungal_trans_2 PF11951.3 OAP65783.1 - 1.2e-05 24.0 0.4 2.4e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 OAP65784.1 - 5.2e-42 143.8 37.3 5.2e-42 143.8 25.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAP65784.1 - 1.9e-10 39.9 23.6 1.2e-09 37.2 16.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 OAP65784.1 - 1.1e-07 30.4 1.8 1.1e-07 30.4 1.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DcpS_C PF11969.3 OAP65785.1 - 8.2e-25 87.2 0.0 1.3e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 OAP65785.1 - 2.4e-23 82.6 0.0 2.5e-22 79.3 0.0 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal