# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- VHS PF00790.19 EMR61256.1 - 2.3e-40 137.7 2.4 3.1e-39 134.0 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EMR61256.1 - 2.2e-15 56.5 3.8 3.7e-15 55.8 3.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EMR61256.1 - 3.4e-06 26.6 16.9 0.0014 18.4 1.5 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 EMR61256.1 - 0.012 15.9 0.9 0.028 14.7 0.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_S30AE PF02482.19 EMR61256.1 - 0.098 13.5 0.0 0.75 10.6 0.1 2.5 3 0 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein OAD_gamma PF04277.13 EMR61256.1 - 0.27 11.9 3.0 0.56 10.8 0.7 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Fer4_2 PF12797.7 EMR61256.1 - 0.32 11.2 7.5 1.4 9.2 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain zf-C2H2_2 PF12756.7 EMR61257.1 - 2.7e-28 98.2 2.7 2.7e-28 98.2 2.7 2.9 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EMR61257.1 - 0.0018 18.5 6.6 0.67 10.3 0.1 3.6 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EMR61257.1 - 0.35 11.8 8.9 4.1 8.5 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMR61257.1 - 1.1 9.9 9.1 5 7.8 0.3 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type AMP-binding PF00501.28 EMR61258.1 - 1.1e-86 291.1 0.0 1.4e-86 290.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FAM47 PF14642.6 EMR61258.1 - 0.051 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 FAM47 family HECT PF00632.25 EMR61259.1 - 1.5e-64 218.4 0.0 3.5e-64 217.2 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Sugar_tr PF00083.24 EMR61260.1 - 4.6e-33 114.8 33.6 2.9e-19 69.3 10.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR61260.1 - 2.4e-16 59.6 51.2 7.9e-13 48.0 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UCH PF00443.29 EMR61261.1 - 9.3e-21 74.5 0.0 1.2e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMR61261.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EMR61261.1 - 0.0061 16.1 0.2 0.69 9.3 0.0 2.4 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase UCR_Fe-S_N PF10399.9 EMR61261.1 - 0.092 12.1 1.2 3.2 7.2 0.2 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal GTP_EFTU PF00009.27 EMR61262.1 - 5.5e-47 159.8 0.0 9e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EMR61262.1 - 1.6e-27 95.6 1.0 4.1e-27 94.3 1.0 1.7 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 EMR61262.1 - 4.6e-10 39.6 0.0 5.4e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EMR61262.1 - 5.4e-08 33.1 0.0 3.8e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EMR61262.1 - 5.8e-06 26.6 1.0 6e-05 23.3 0.1 2.8 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain Roc PF08477.13 EMR61262.1 - 0.00025 21.2 0.0 0.039 14.2 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMR61262.1 - 0.0014 18.1 0.0 0.85 9.0 0.0 2.4 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 EMR61262.1 - 0.0062 16.0 1.0 3.2 7.2 0.0 2.7 2 1 1 3 3 3 2 ADP-ribosylation factor family FeoB_N PF02421.18 EMR61262.1 - 0.013 15.0 0.1 0.32 10.5 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 EMR61262.1 - 0.032 13.8 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 EMR61262.1 - 0.034 13.7 0.2 0.56 9.8 0.0 2.3 1 1 1 2 2 2 0 Ras family Septin PF00735.18 EMR61262.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 EMR61262.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain HSP70 PF00012.20 EMR61263.1 - 3e-264 877.8 14.6 3.4e-264 877.6 14.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMR61263.1 - 5.2e-19 68.2 1.9 1.9e-17 63.1 0.4 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EMR61263.1 - 0.0027 18.1 4.3 6.1 7.3 0.1 3.7 3 1 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 EMR61263.1 - 0.016 14.2 0.4 0.18 10.7 0.3 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EMR61263.1 - 0.027 13.7 3.1 0.13 11.5 0.1 2.9 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Cu-oxidase_2 PF07731.14 EMR61264.1 - 4.1e-39 133.5 9.7 3.1e-38 130.6 0.5 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMR61264.1 - 8.7e-38 129.0 2.5 8.7e-38 129.0 2.5 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EMR61264.1 - 1.2e-32 113.2 1.2 2e-32 112.5 0.2 2.0 2 0 0 2 2 2 1 Multicopper oxidase Big_11 PF18200.1 EMR61264.1 - 0.063 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain YPEB PF14620.6 EMR61265.1 - 0.023 14.1 0.3 0.029 13.7 0.3 1.1 1 0 0 1 1 1 0 YpeB sporulation DUF5071 PF16804.5 EMR61265.1 - 0.023 15.0 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) DUF2795 PF11387.8 EMR61265.1 - 0.041 14.1 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) DUF5344 PF17279.2 EMR61265.1 - 0.12 13.0 0.2 0.42 11.2 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5344) CBM_X2 PF03442.14 EMR61266.1 - 0.023 14.8 0.0 6.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain X2 Cnn_1N PF07989.11 EMR61267.1 - 2.7e-21 75.5 8.4 2.7e-21 75.5 8.4 10.4 7 2 5 12 12 12 1 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 EMR61267.1 - 5.6e-07 29.8 11.3 5.6e-07 29.8 11.3 9.2 11 0 0 11 11 11 1 Micro-tubular organiser Mto1 C-term Mto2-binding region DegS PF05384.11 EMR61267.1 - 0.0041 16.6 4.8 0.0041 16.6 4.8 6.8 5 1 1 7 7 7 1 Sensor protein DegS Fib_alpha PF08702.10 EMR61267.1 - 0.37 11.0 55.9 0.096 12.9 1.4 7.6 3 2 4 8 8 8 0 Fibrinogen alpha/beta chain family adh_short PF00106.25 EMR61268.1 - 1.5e-17 63.7 0.0 6.5e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR61268.1 - 3.6e-05 23.4 0.0 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR61268.1 - 5.6e-05 23.1 0.0 9.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF998 PF06197.13 EMR61268.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF998) AzlD PF05437.12 EMR61268.1 - 0.16 12.2 0.6 0.37 11.0 0.1 1.8 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) EthD PF07110.11 EMR61269.1 - 5.3e-18 66.0 1.8 6.5e-18 65.7 1.8 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EMR61269.1 - 0.0044 17.5 0.1 0.0065 16.9 0.1 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase LolB PF03550.14 EMR61269.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.4 2 0 0 2 2 2 0 Outer membrane lipoprotein LolB zf-C2H2 PF00096.26 EMR61271.1 - 0.0012 19.2 0.8 0.39 11.3 0.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF5024 PF16427.5 EMR61272.1 - 0.027 14.8 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) IucA_IucC PF04183.12 EMR61273.1 - 0.00014 21.5 0.0 0.00034 20.2 0.0 1.6 2 0 0 2 2 2 1 IucA / IucC family DUF726 PF05277.12 EMR61274.1 - 1.3e-125 418.9 2.2 1.9e-125 418.4 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) p450 PF00067.22 EMR61275.1 - 7.3e-42 143.7 0.0 9.9e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PH PF00169.29 EMR61276.1 - 1.6e-09 38.2 1.0 2.1e-07 31.4 0.0 2.6 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 EMR61276.1 - 0.00061 20.1 0.0 0.0017 18.7 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain Peptidase_S9_N PF02897.15 EMR61276.1 - 0.12 11.2 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain H_lectin PF09458.10 EMR61277.1 - 7.6e-07 29.2 0.1 1.6e-06 28.2 0.0 1.5 2 0 0 2 2 2 1 H-type lectin domain SpoIIE PF07228.12 EMR61278.1 - 3.6e-06 27.0 0.1 1.1e-05 25.5 0.1 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EMR61278.1 - 0.00081 19.1 0.0 0.1 12.2 0.0 2.1 1 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EMR61278.1 - 0.0028 17.3 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3719 PF12516.8 EMR61278.1 - 0.034 13.8 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) DUF1580 PF07618.11 EMR61279.1 - 0.039 13.6 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) PCI PF01399.27 EMR61280.1 - 4.5e-12 46.4 0.0 1.2e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain Lipase_GDSL_2 PF13472.6 EMR61281.1 - 1.1e-15 58.5 0.0 1.6e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR61281.1 - 2e-07 31.2 0.0 4.9e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase VPS9 PF02204.18 EMR61283.1 - 2.8e-30 104.6 0.0 4.6e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EMR61283.1 - 9.3e-17 61.1 0.2 2e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EMR61283.1 - 6.9e-09 35.2 0.1 5.3e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 CUE domain Fcf1 PF04900.12 EMR61284.1 - 3.5e-30 104.3 0.0 5.9e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 EMR61284.1 - 1.2 7.4 9.4 1.7 6.9 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Radical_SAM PF04055.21 EMR61285.1 - 7.6e-17 62.2 1.5 3e-16 60.3 0.5 2.3 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EMR61285.1 - 3.3e-06 27.4 0.6 1.1e-05 25.7 0.2 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMR61285.1 - 0.00012 22.1 0.2 0.0003 20.9 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain MFS_1 PF07690.16 EMR61286.1 - 2.2e-38 132.1 28.6 2.2e-38 132.1 28.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61286.1 - 3.9e-13 49.1 7.9 3.9e-13 49.1 7.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 EMR61286.1 - 0.05 11.9 3.5 0.12 10.6 3.3 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_cc PF11790.8 EMR61287.1 - 1.9e-49 168.4 2.5 2.6e-49 168.0 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core HSP70 PF00012.20 EMR61288.1 - 6.7e-10 37.8 0.0 2.1e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein FtsA PF14450.6 EMR61288.1 - 0.00056 20.3 0.7 0.007 16.8 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA Helicase_C PF00271.31 EMR61289.1 - 1.3e-10 41.6 0.2 2.2e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_61 PF03443.14 EMR61290.1 - 1.4e-19 70.9 0.1 1.6e-19 70.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PepSY_2 PF13670.6 EMR61290.1 - 0.012 15.5 0.1 0.012 15.5 0.1 1.7 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain DEC-1_N PF04625.13 EMR61291.1 - 2.1 7.3 4.3 2.9 6.8 4.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RabGAP-TBC PF00566.18 EMR61292.1 - 3.9e-33 114.9 0.7 9.3e-17 61.4 0.0 3.2 2 1 1 3 3 3 3 Rab-GTPase-TBC domain XRCC4 PF06632.12 EMR61293.1 - 2.4e-12 46.4 4.7 1.8e-11 43.5 4.7 2.0 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.8 EMR61293.1 - 0.00047 20.3 4.1 0.00074 19.7 4.1 1.3 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain GCIP PF13324.6 EMR61293.1 - 0.13 11.9 1.6 0.21 11.2 1.6 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Oxidored_FMN PF00724.20 EMR61300.1 - 3.1e-75 253.6 0.0 4.3e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 EMR61300.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) polyprenyl_synt PF00348.17 EMR61301.1 - 2e-73 246.6 0.0 3.1e-73 246.0 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EMR61301.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Ras PF00071.22 EMR61303.1 - 2.6e-40 137.7 0.0 8.3e-38 129.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EMR61303.1 - 3.7e-31 107.8 0.0 5.6e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR61303.1 - 5.9e-10 38.9 0.0 9.3e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMR61303.1 - 0.00016 21.7 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EMR61303.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EMR61303.1 - 0.04 14.3 0.1 0.096 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DLIC PF05783.11 EMR61303.1 - 0.11 11.3 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) RTP1_C2 PF10304.9 EMR61303.1 - 0.17 11.6 0.3 0.3 10.8 0.3 1.4 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 Gtr1_RagA PF04670.12 EMR61303.1 - 0.23 10.8 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Med3 PF11593.8 EMR61303.1 - 0.7 9.0 3.9 0.9 8.7 3.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4632 PF15451.6 EMR61304.1 - 0.23 11.6 1.6 0.29 11.2 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4632) Metallophos PF00149.28 EMR61305.1 - 8.1e-21 75.4 0.0 1.8e-11 45.0 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMR61305.1 - 0.031 14.7 0.1 0.078 13.4 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Atg14 PF10186.9 EMR61306.1 - 0.0022 17.2 16.0 0.0033 16.6 16.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 EMR61306.1 - 0.0059 17.1 19.1 0.0088 16.5 19.1 1.2 1 0 0 1 1 1 1 Fez1 Cnn_1N PF07989.11 EMR61306.1 - 0.006 16.7 13.7 0.043 14.0 1.6 3.2 2 1 1 3 3 3 2 Centrosomin N-terminal motif 1 Macoilin PF09726.9 EMR61306.1 - 0.013 14.1 11.4 0.017 13.7 11.4 1.2 1 0 0 1 1 1 0 Macoilin family LMBR1 PF04791.16 EMR61306.1 - 0.91 8.4 2.6 1.2 8.0 2.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YABBY PF04690.13 EMR61306.1 - 2.6 8.6 7.0 5.4 7.6 7.0 1.6 1 0 0 1 1 1 0 YABBY protein V_ATPase_I PF01496.19 EMR61306.1 - 5.1 4.9 12.4 6.5 4.5 12.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.18 EMR61306.1 - 7.6 6.8 9.7 0.76 10.1 2.0 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper adh_short PF00106.25 EMR61308.1 - 5.9e-14 52.0 0.0 1.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR61308.1 - 8e-10 38.7 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NTP_transf_9 PF04248.12 EMR61309.1 - 5.4e-32 109.6 4.3 6.1e-32 109.4 4.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Vma12 PF11712.8 EMR61310.1 - 6.1e-42 143.0 0.0 1e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase SCIMP PF15050.6 EMR61310.1 - 0.01 16.3 0.3 0.24 11.8 0.1 2.4 2 0 0 2 2 2 0 SCIMP protein DUF1772 PF08592.11 EMR61310.1 - 0.043 14.1 0.2 0.072 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF4149 PF13664.6 EMR61310.1 - 0.056 13.8 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) UPF0242 PF06785.11 EMR61310.1 - 0.096 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FMN_dh PF01070.18 EMR61311.1 - 6.2e-125 416.8 0.3 7.8e-125 416.5 0.3 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EMR61311.1 - 2.1e-22 79.0 0.1 4.4e-22 78.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EMR61311.1 - 5.6e-07 29.0 0.0 9.3e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EMR61311.1 - 0.00054 19.1 0.1 0.00094 18.3 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMR61311.1 - 0.0022 17.4 0.7 0.0022 17.4 0.7 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 EMR61311.1 - 0.1 12.0 0.8 3.5 7.0 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein DUF4965 PF16335.5 EMR61312.1 - 3e-68 228.9 0.1 7.5e-68 227.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EMR61312.1 - 1.3e-43 149.4 1.8 4.5e-42 144.3 1.8 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 EMR61312.1 - 5.8e-41 140.8 0.7 1.9e-40 139.0 0.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 EMR61312.1 - 3.6e-12 45.7 0.1 7.8e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 EMR61312.1 - 0.00019 21.0 0.1 0.00038 20.1 0.1 1.5 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term AtuA PF07287.11 EMR61314.1 - 4.6e-118 394.0 0.0 6e-118 393.6 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF2685 PF10886.8 EMR61314.1 - 0.13 12.5 0.0 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) KH_8 PF17903.1 EMR61315.1 - 1.4e-29 102.0 0.2 3.8e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Krr1 KH1 domain Bystin PF05291.11 EMR61316.1 - 8.5e-131 435.5 0.0 1.1e-130 435.2 0.0 1.0 1 0 0 1 1 1 1 Bystin Pkinase PF00069.25 EMR61317.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Sugar_tr PF00083.24 EMR61319.1 - 5.6e-47 160.6 13.9 7.2e-47 160.3 13.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR61319.1 - 1.7e-20 73.3 22.6 2.5e-20 72.7 22.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF383 PF04063.14 EMR61320.1 - 3.6e-63 212.7 0.0 9.7e-63 211.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EMR61320.1 - 2.7e-24 84.8 1.6 4.9e-24 83.9 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF384) COA2 PF17051.5 EMR61321.1 - 2.3e-05 24.4 0.4 3.6e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Fungal_trans PF04082.18 EMR61322.1 - 0.00013 21.1 0.2 0.00033 19.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.13 EMR61323.1 - 5.5e-43 147.2 0.0 6.8e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR61323.1 - 3.1e-25 89.1 0.1 4.7e-25 88.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR61323.1 - 8e-11 41.9 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR61323.1 - 7.3e-05 21.9 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EMR61323.1 - 0.012 16.2 0.3 0.028 15.0 0.3 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 EMR61323.1 - 0.016 15.5 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_4 PF13439.6 EMR61323.1 - 0.021 14.8 0.1 0.056 13.5 0.1 1.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_2 PF03446.15 EMR61323.1 - 0.024 14.8 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Mur_ligase PF01225.25 EMR61323.1 - 0.025 14.9 0.1 0.056 13.8 0.1 1.7 1 0 0 1 1 1 0 Mur ligase family, catalytic domain RmlD_sub_bind PF04321.17 EMR61323.1 - 0.037 13.1 0.3 0.077 12.1 0.3 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 EMR61323.1 - 0.05 13.0 1.0 0.081 12.4 1.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EMR61323.1 - 0.069 12.5 0.2 0.36 10.2 0.2 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_trans_4_4 PF13579.6 EMR61323.1 - 0.098 13.1 1.6 0.16 12.4 1.6 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain zf-C2H2_3 PF13878.6 EMR61324.1 - 2.6e-13 49.6 0.9 4.7e-13 48.7 0.9 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO YiaAB PF05360.14 EMR61325.1 - 0.069 13.4 1.4 0.1 12.9 1.4 1.3 1 0 0 1 1 1 0 yiaA/B two helix domain RTA1 PF04479.13 EMR61326.1 - 3.2e-62 209.8 5.0 4.3e-62 209.4 5.0 1.1 1 0 0 1 1 1 1 RTA1 like protein UNC-50 PF05216.13 EMR61326.1 - 0.05 13.2 0.9 2.7 7.5 0.0 2.5 3 0 0 3 3 3 0 UNC-50 family PALP PF00291.25 EMR61327.1 - 2.3e-45 155.3 0.4 2.9e-45 155.0 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.18 EMR61327.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 LytB protein NAD_binding_11 PF14833.6 EMR61328.1 - 6.6e-29 100.6 0.0 7.6e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Anp1 PF03452.14 EMR61330.1 - 2.1e-29 102.8 0.5 4.1e-29 101.8 0.5 1.5 1 1 0 1 1 1 1 Anp1 NTP_transf_3 PF12804.7 EMR61330.1 - 0.0067 16.8 0.2 0.011 16.1 0.2 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF3477 PF11963.8 EMR61330.1 - 0.21 10.8 0.5 0.3 10.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) Acyl-CoA_dh_1 PF00441.24 EMR61332.1 - 9.6e-32 110.3 0.7 1.8e-31 109.4 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMR61332.1 - 3.2e-30 105.1 0.2 6.4e-30 104.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EMR61332.1 - 3.5e-27 94.5 0.2 6.8e-27 93.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMR61332.1 - 2.3e-11 44.1 0.4 2.3e-11 44.1 0.4 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EMR61332.1 - 0.0014 18.4 0.2 0.0056 16.4 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 EMR61335.1 - 3.6e-134 448.1 0.0 4.7e-134 447.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EMR61335.1 - 0.0016 18.0 0.7 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) adh_short_C2 PF13561.6 EMR61336.1 - 5.1e-53 180.0 0.0 7.3e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR61336.1 - 7.8e-37 126.6 0.2 1.1e-36 126.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR61336.1 - 3.4e-12 46.6 0.1 4.9e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR61336.1 - 0.0043 16.5 0.0 0.007 15.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR61336.1 - 0.064 12.6 0.2 0.73 9.2 0.2 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pectinesterase PF01095.19 EMR61338.1 - 4.2e-49 166.9 1.7 5.7e-49 166.4 1.7 1.1 1 0 0 1 1 1 1 Pectinesterase Beta_helix_2 PF18835.1 EMR61338.1 - 0.023 14.4 1.8 0.028 14.2 0.3 2.0 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase FSH1 PF03959.13 EMR61339.1 - 1.3e-25 90.4 0.0 2e-25 89.7 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) p450 PF00067.22 EMR61340.1 - 2.6e-55 188.0 0.0 3.2e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 EMR61341.1 - 2.3e-18 66.1 0.0 5e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 Transferase family Esterase_phd PF10503.9 EMR61342.1 - 1.2e-06 28.2 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Creatinase_N PF01321.18 EMR61342.1 - 0.18 12.4 0.2 5.2 7.7 0.1 2.6 2 1 0 2 2 2 0 Creatinase/Prolidase N-terminal domain CAP_N PF01213.19 EMR61343.1 - 3.4 7.0 10.6 6.5 6.1 10.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EMR61343.1 - 3.6 7.6 8.8 6.1 6.9 8.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator KR PF08659.10 EMR61344.1 - 3.2e-66 222.7 1.8 8.1e-66 221.4 1.8 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EMR61344.1 - 4.3e-49 167.4 0.0 6.9e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EMR61344.1 - 1.7e-41 140.9 0.1 5.2e-41 139.4 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EMR61344.1 - 1.9e-40 139.3 0.3 1.9e-40 139.3 0.3 1.8 2 0 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.26 EMR61344.1 - 1e-28 100.6 0.0 2.5e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 EMR61344.1 - 4.6e-20 72.1 0.2 4.2e-19 69.1 0.1 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EMR61344.1 - 1.6e-14 55.1 0.1 1.7e-13 51.7 0.0 2.9 4 0 0 4 4 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR61344.1 - 2.2e-14 53.4 0.7 2.2e-14 53.4 0.7 2.4 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EMR61344.1 - 1.3e-13 51.1 1.2 3.7e-13 49.6 0.1 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR61344.1 - 4.4e-07 29.7 0.7 1.4e-06 28.2 0.7 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EMR61344.1 - 1.9e-06 28.1 0.1 5.3e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 EMR61344.1 - 7.9e-06 25.2 0.0 1.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMR61344.1 - 5.2e-05 22.8 0.1 0.0001 21.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR61344.1 - 0.00031 20.2 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMR61344.1 - 0.00062 18.9 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EMR61344.1 - 0.01 15.4 0.0 0.042 13.4 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Methyltransf_25 PF13649.6 EMR61345.1 - 1.4e-10 41.8 0.0 2.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR61345.1 - 9.8e-09 35.2 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR61345.1 - 2.9e-08 34.3 0.0 5.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR61345.1 - 4.1e-08 33.2 0.0 6.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR61345.1 - 4.8e-07 30.5 0.0 8.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR61345.1 - 1.6e-06 27.6 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 EMR61345.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain p450 PF00067.22 EMR61346.1 - 5.6e-44 150.6 0.0 6.4e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Caps_synth PF05704.12 EMR61347.1 - 6e-11 42.2 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 EMR61347.1 - 0.00019 22.0 0.0 0.00036 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Methyltransf_11 PF08241.12 EMR61348.1 - 8.1e-08 32.8 0.0 1.4e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR61348.1 - 2.2e-07 31.5 0.0 3.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR61348.1 - 1.8e-06 28.6 0.0 2.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR61348.1 - 0.0001 22.2 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR61348.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Sigma70_ner PF04546.13 EMR61349.1 - 0.007 16.3 0.4 0.007 16.3 0.4 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region YL1 PF05764.13 EMR61349.1 - 0.091 12.9 3.5 0.12 12.4 3.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 EMR61349.1 - 0.12 10.6 1.9 0.14 10.4 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 EMR61349.1 - 0.22 12.5 9.5 0.33 12.0 9.5 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DNA_pol_phi PF04931.13 EMR61349.1 - 0.95 7.5 6.2 1.1 7.3 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EMR61349.1 - 3.2 6.8 9.4 3.9 6.5 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sterol-sensing PF12349.8 EMR61350.1 - 4.2e-35 120.8 8.7 7.8e-35 120.0 8.7 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EMR61350.1 - 4.2e-07 28.5 3.2 6.1e-07 27.9 3.2 1.1 1 0 0 1 1 1 1 Patched family MMPL PF03176.15 EMR61350.1 - 0.23 10.3 0.0 0.23 10.3 0.0 2.2 2 0 0 2 2 2 0 MMPL family NAD_binding_10 PF13460.6 EMR61351.1 - 8.8e-05 22.5 0.1 0.0002 21.3 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Ribosomal_60s PF00428.19 EMR61351.1 - 0.0036 17.9 0.2 0.0057 17.2 0.2 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein AAA_lid_2 PF17863.1 EMR61352.1 - 0.024 14.5 0.3 0.062 13.2 0.3 1.7 1 0 0 1 1 1 0 AAA lid domain Hydin_ADK PF17213.3 EMR61352.1 - 2.6 8.3 4.5 8.5 6.6 0.3 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain GDA1_CD39 PF01150.17 EMR61353.1 - 5.1e-100 335.1 0.0 6.8e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PUL PF08324.11 EMR61354.1 - 1.7e-59 201.4 0.0 2.5e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 EMR61354.1 - 5.2e-14 52.1 0.0 1.7e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EMR61354.1 - 2.5e-06 27.9 0.1 1.9e-05 25.0 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EMR61354.1 - 4.4e-05 23.4 0.0 7.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EMR61354.1 - 0.0049 16.3 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DSBA PF01323.20 EMR61354.1 - 0.015 15.1 0.1 5.2 6.8 0.0 2.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 EMR61354.1 - 0.029 14.4 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.10 EMR61354.1 - 0.037 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 EMR61354.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Cupin_8 PF13621.6 EMR61356.1 - 1.6e-67 227.9 0.0 1.9e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EMR61356.1 - 6.3e-06 25.9 0.1 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 EMR61356.1 - 0.03 14.7 0.0 0.34 11.3 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Ribosomal_60s PF00428.19 EMR61356.1 - 0.51 11.0 3.7 1.2 9.8 3.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF72 PF01904.18 EMR61357.1 - 0.054 13.6 6.5 0.35 10.9 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF72 MrpF_PhaF PF04066.13 EMR61357.1 - 1.4 9.4 5.5 3.1 8.3 5.5 1.6 1 0 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Melibiase_2 PF16499.5 EMR61358.1 - 2.7e-16 59.6 0.3 5.1e-08 32.4 1.0 2.1 1 1 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 EMR61358.1 - 1.9e-11 43.9 0.8 3.8e-11 42.9 0.1 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Aminotran_1_2 PF00155.21 EMR61359.1 - 3.3e-33 115.4 0.0 4.3e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.28 EMR61360.1 - 4.5e-85 285.8 0.1 6.2e-85 285.3 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR61360.1 - 1.5e-26 93.1 1.0 5.8e-25 88.1 0.9 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EMR61360.1 - 2.9e-19 68.7 0.9 9.6e-19 67.1 0.4 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 EMR61360.1 - 0.13 12.2 0.0 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Glyco_hydro_72 PF03198.14 EMR61361.1 - 6.1e-100 334.5 0.0 1.4e-99 333.3 0.0 1.6 2 0 0 2 2 2 1 Glucanosyltransferase Cellulase PF00150.18 EMR61361.1 - 0.0036 16.8 0.3 0.022 14.2 0.3 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EMR61361.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_6 PF01341.17 EMR61362.1 - 3.6e-91 306.1 0.0 4.6e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Ysc84 PF04366.12 EMR61364.1 - 3e-47 159.5 0.0 3e-47 159.5 0.0 1.5 2 0 0 2 2 2 1 Las17-binding protein actin regulator HET PF06985.11 EMR61365.1 - 5.6e-12 46.2 4.5 1.3e-11 45.0 2.0 2.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Utp11 PF03998.13 EMR61365.1 - 0.048 13.6 2.6 0.088 12.7 2.6 1.4 1 0 0 1 1 1 0 Utp11 protein Zw10 PF06248.13 EMR61365.1 - 0.1 11.2 0.2 0.16 10.5 0.2 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 PYC_OADA PF02436.18 EMR61365.1 - 0.16 11.7 0.3 0.43 10.3 0.3 1.7 1 0 0 1 1 1 0 Conserved carboxylase domain GvpO PF05800.11 EMR61365.1 - 1.3 9.1 3.8 3.4 7.7 0.2 2.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO KR PF08659.10 EMR61366.1 - 6.7e-30 104.3 0.0 2e-29 102.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.12 EMR61366.1 - 1.4e-18 67.4 0.0 1.1e-17 64.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR61366.1 - 1.2e-14 54.8 0.1 8.4e-14 52.1 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR61366.1 - 1.5e-14 54.2 0.0 2.6e-12 46.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR61366.1 - 1.2e-12 48.3 0.0 3e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR61366.1 - 5.1e-12 45.8 0.0 6.9e-10 38.9 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain PP-binding PF00550.25 EMR61366.1 - 1.3e-06 28.7 0.1 4.6e-06 26.9 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EMR61366.1 - 2.6e-06 27.0 0.0 7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ubie_methyltran PF01209.18 EMR61366.1 - 1.9e-05 24.1 0.0 3.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 EMR61366.1 - 0.001 18.7 0.0 0.0045 16.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_33 PF10017.9 EMR61366.1 - 0.014 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent RrnaAD PF00398.20 EMR61366.1 - 0.065 12.3 0.0 3 6.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 EMR61366.1 - 0.098 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 EMR61366.1 - 0.1 12.4 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EMR61366.1 - 0.16 13.0 0.0 1.3 10.1 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 EMR61367.1 - 3.3e-59 200.4 0.0 6.3e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR61367.1 - 9.1e-28 97.2 0.0 4.6e-19 68.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EMR61367.1 - 0.0012 18.3 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EMR61367.1 - 0.012 14.4 0.7 0.019 13.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EMR61367.1 - 0.02 14.3 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 EMR61368.1 - 9.5e-15 54.2 0.0 1.6e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EMR61368.1 - 0.00019 21.9 2.7 0.00019 21.9 2.7 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EMR61368.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif DFRP_C PF16543.5 EMR61369.1 - 2.4e-24 85.6 6.1 2.4e-24 85.6 6.1 3.6 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EMR61369.1 - 6.5e-07 29.1 1.0 6.5e-07 29.1 1.0 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EMR61369.1 - 2.1e-06 28.4 14.8 2.2e-06 28.3 3.0 3.4 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 EMR61369.1 - 9.8e-05 22.3 6.6 9.8e-05 22.3 6.6 3.3 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_4 PF18044.1 EMR61369.1 - 0.00027 20.7 9.4 0.0011 18.8 2.0 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EMR61369.1 - 0.044 14.0 5.4 0.15 12.2 0.7 2.7 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EMR61369.1 - 0.054 14.0 5.1 0.054 14.0 5.1 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MFS_1 PF07690.16 EMR61370.1 - 3.7e-18 65.6 21.2 3.7e-18 65.6 21.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 EMR61370.1 - 2.1 6.9 18.9 0.0078 14.9 5.7 2.2 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like PCNA_N PF00705.18 EMR61371.1 - 0.091 12.5 0.1 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain Acetyltransf_1 PF00583.25 EMR61372.1 - 9.9e-14 51.6 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EMR61372.1 - 8.5e-13 49.2 0.0 1.2e-12 48.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR61372.1 - 7.4e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMR61372.1 - 1.9e-05 24.4 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR61372.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR61372.1 - 0.075 13.0 0.1 0.19 11.7 0.1 1.8 1 1 0 1 1 1 0 FR47-like protein TPR_10 PF13374.6 EMR61372.1 - 1.8 8.5 4.0 16 5.6 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2_aberr PF17017.5 EMR61373.1 - 0.02 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger SPT6_acidic PF14632.6 EMR61373.1 - 0.48 11.0 9.2 0.084 13.5 4.8 2.0 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DUF2722 PF10846.8 EMR61375.1 - 0.74 8.7 7.9 1.1 8.2 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BSP_II PF05432.11 EMR61375.1 - 0.91 9.2 25.2 1.3 8.7 25.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DNA_pol3_delta2 PF13177.6 EMR61376.1 - 4.2e-11 42.9 0.0 8.2e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EMR61376.1 - 1.1e-06 29.2 0.0 2.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMR61376.1 - 2.5e-06 27.8 0.2 6.5e-05 23.2 0.1 2.7 1 1 1 2 2 2 1 AAA domain Rep_fac_C PF08542.11 EMR61376.1 - 0.00015 22.1 0.2 0.00043 20.6 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_24 PF13479.6 EMR61376.1 - 0.00019 21.2 0.6 0.001 18.9 0.4 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMR61376.1 - 0.00026 21.4 0.9 0.0062 16.9 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EMR61376.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 EMR61376.1 - 0.022 15.3 0.0 0.049 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Resolvase PF00239.21 EMR61376.1 - 0.024 14.7 0.1 1.3 9.1 0.2 2.8 4 0 0 4 4 4 0 Resolvase, N terminal domain T4SS-DNA_transf PF02534.14 EMR61376.1 - 0.055 12.3 0.1 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ATPase_2 PF01637.18 EMR61376.1 - 0.11 12.5 0.1 0.36 10.7 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EMR61376.1 - 0.22 11.5 0.7 1.5 8.9 0.7 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.16 EMR61377.1 - 1.7e-28 99.6 40.8 8.8e-28 97.2 40.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR61377.1 - 4.6e-19 68.3 15.7 5.8e-19 67.9 15.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 EMR61378.1 - 1.4e-21 76.9 0.1 2.6e-21 76.0 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR61378.1 - 8.2e-21 74.6 0.1 1.1e-20 74.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR61378.1 - 1.4e-06 28.3 0.0 2.5e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 KR domain p450 PF00067.22 EMR61379.1 - 9.8e-50 169.6 0.0 1.5e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.6 EMR61380.1 - 5.2e-24 84.3 0.4 3.8e-23 81.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR61380.1 - 1e-14 54.3 0.0 2.5e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR61380.1 - 7.4e-06 26.1 0.0 1.8e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR61380.1 - 9.9e-05 22.7 0.0 0.0031 17.9 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR61380.1 - 0.0014 18.7 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ThiF PF00899.21 EMR61381.1 - 5.3e-113 376.4 0.0 9.6e-75 251.1 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EMR61381.1 - 6.5e-94 314.5 1.5 1.1e-93 313.8 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EMR61381.1 - 1.9e-31 108.1 0.1 4.5e-31 106.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EMR61381.1 - 2e-31 108.6 0.3 5.6e-31 107.1 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin fold domain E1_4HB PF16191.5 EMR61381.1 - 5.2e-26 90.6 1.8 7.2e-26 90.2 0.2 2.2 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 EMR61381.1 - 0.057 13.9 0.5 1.5 9.3 0.0 3.5 5 0 0 5 5 5 0 Putative NAD(P)-binding DDHD PF02862.17 EMR61382.1 - 3.8e-63 213.6 0.4 7.7e-62 209.4 0.0 2.6 2 0 0 2 2 2 1 DDHD domain LIDHydrolase PF10230.9 EMR61382.1 - 0.042 13.4 0.1 0.22 11.0 0.0 2.1 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase NPR3 PF03666.13 EMR61382.1 - 0.85 8.3 0.0 0.85 8.3 0.0 3.2 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 UCH PF00443.29 EMR61383.1 - 2.7e-40 138.5 0.0 4e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMR61383.1 - 4.4e-08 33.1 0.0 3.3e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.16 EMR61384.1 - 1.5e-32 112.9 31.4 1.5e-32 112.9 31.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-CCHC PF00098.23 EMR61386.1 - 4.7e-46 152.9 62.5 4.3e-09 36.0 4.5 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EMR61386.1 - 7.3e-09 35.2 40.2 0.028 14.2 0.8 7.0 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 EMR61386.1 - 2e-05 24.2 35.7 0.028 14.1 0.3 6.2 5 1 1 6 6 6 4 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 EMR61386.1 - 0.00024 21.0 46.7 0.047 13.7 0.4 6.4 4 2 3 7 7 7 5 Zinc knuckle zf-CCHC_2 PF13696.6 EMR61386.1 - 0.026 14.4 2.4 0.026 14.4 2.4 6.6 6 0 0 6 6 6 0 Zinc knuckle SAE2 PF08573.10 EMR61387.1 - 5.6e-29 101.5 0.1 5.6e-29 101.5 0.1 2.8 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Spc7 PF08317.11 EMR61387.1 - 0.00053 19.0 4.8 0.00094 18.1 4.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 EMR61387.1 - 0.011 16.0 8.1 0.011 16.0 8.1 2.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) CEP63 PF17045.5 EMR61387.1 - 0.027 14.4 10.9 0.064 13.2 10.6 1.7 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa UPF0242 PF06785.11 EMR61387.1 - 0.037 14.2 8.8 0.062 13.4 8.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 EMR61387.1 - 0.083 13.2 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YkyA PF10368.9 EMR61387.1 - 0.088 12.5 6.6 0.18 11.4 6.5 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF641 PF04859.12 EMR61387.1 - 0.4 11.0 5.9 0.14 12.5 2.3 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4337 PF14235.6 EMR61387.1 - 0.6 10.2 5.3 6.8 6.8 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF724 PF05266.14 EMR61387.1 - 0.73 9.6 4.9 0.41 10.4 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 EMR61387.1 - 2.3 8.6 4.9 0.85 10.0 1.5 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4164 PF13747.6 EMR61387.1 - 4.5 7.6 11.1 2.9 8.2 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) MFS_1 PF07690.16 EMR61388.1 - 9.7e-31 107.0 58.8 9.7e-31 107.0 58.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1418 PF07214.12 EMR61388.1 - 0.33 10.8 2.3 1.8 8.5 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1418) RNA_pol_Rpb1_5 PF04998.17 EMR61390.1 - 1.6e-74 250.7 0.1 2.6e-74 250.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMR61390.1 - 1.4e-70 236.8 0.0 7.8e-70 234.4 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EMR61390.1 - 1.2e-64 218.6 0.0 1.3e-61 208.7 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EMR61390.1 - 9e-39 132.9 0.0 1.8e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EMR61390.1 - 7.1e-28 96.7 1.1 1.3e-27 95.9 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DWNN PF08783.11 EMR61390.1 - 0.022 15.0 0.1 0.083 13.2 0.1 1.9 1 0 0 1 1 1 0 DWNN domain zf-ribbon_3 PF13248.6 EMR61390.1 - 1.6 8.3 3.8 1.1 8.7 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain SAP PF02037.27 EMR61391.1 - 0.0042 16.8 1.5 0.0042 16.8 1.5 1.9 2 0 0 2 2 2 1 SAP domain Telomere_Sde2_2 PF13297.6 EMR61391.1 - 0.024 14.3 0.3 0.045 13.4 0.3 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal CDC45 PF02724.14 EMR61391.1 - 2 6.6 22.0 0.41 8.9 11.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Surp PF01805.20 EMR61392.1 - 6.7e-11 42.0 0.0 1.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Surp module MFS_1 PF07690.16 EMR61393.1 - 2.6e-41 141.7 33.1 7.2e-32 110.7 15.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61393.1 - 3.8e-08 32.6 3.7 2.2e-06 26.8 0.2 2.7 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 EMR61393.1 - 0.027 12.9 15.4 0.18 10.2 2.9 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.20 EMR61393.1 - 0.047 12.0 6.6 0.32 9.2 0.4 3.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_5 PF05631.14 EMR61393.1 - 0.058 12.3 5.4 0.013 14.5 2.1 1.5 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM DUF3246 PF11596.8 EMR61393.1 - 0.093 12.2 5.0 0.18 11.2 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) MFS_1_like PF12832.7 EMR61393.1 - 0.14 11.0 14.9 0.022 13.6 5.1 2.6 2 2 0 3 3 3 0 MFS_1 like family FAM176 PF14851.6 EMR61393.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.9 3 1 0 3 3 3 0 FAM176 family MFMR_assoc PF16596.5 EMR61393.1 - 0.3 11.5 7.2 0.4 11.2 5.8 1.9 2 0 0 2 2 2 0 Disordered region downstream of MFMR Chorion_2 PF03964.15 EMR61393.1 - 0.71 10.7 7.4 4.1 8.3 1.5 2.4 2 0 0 2 2 2 0 Chorion family 2 NOA36 PF06524.12 EMR61393.1 - 1.9 7.7 6.5 3.4 6.9 6.5 1.3 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 EMR61394.1 - 1.8e-27 96.2 31.3 5.1e-26 91.4 26.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61394.1 - 1e-14 54.3 1.4 1e-14 54.3 1.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMR61394.1 - 4e-07 28.8 1.7 6e-07 28.3 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 EMR61394.1 - 0.001 17.4 0.0 0.001 17.4 0.0 2.0 2 0 0 2 2 2 1 BT1 family DUF2304 PF10066.9 EMR61394.1 - 0.42 10.8 11.4 13 6.0 7.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DUF4381 PF14316.6 EMR61394.1 - 2.7 8.2 4.2 9.4 6.5 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DAO PF01266.24 EMR61395.1 - 1.9e-43 149.4 0.6 2.4e-43 149.1 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR61395.1 - 2e-07 31.2 0.1 0.015 15.3 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMR61395.1 - 2.9e-06 27.4 0.0 6.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR61395.1 - 4.4e-05 22.9 0.1 0.2 10.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMR61395.1 - 0.00034 19.8 0.0 0.0016 17.6 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 EMR61395.1 - 0.0038 16.7 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 EMR61395.1 - 0.0099 14.8 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 EMR61395.1 - 0.015 14.4 0.4 0.65 9.0 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 EMR61395.1 - 0.031 14.5 0.0 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 EMR61395.1 - 0.084 11.9 0.1 1.2 8.1 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein TBP PF00352.21 EMR61396.1 - 5.6e-66 218.5 0.1 6.2e-32 109.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EMR61396.1 - 0.00013 22.1 0.0 0.24 11.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EMR61396.1 - 0.13 12.1 0.1 0.7 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) KH_1 PF00013.29 EMR61397.1 - 2.9e-70 232.0 25.3 1.1e-13 50.7 0.1 11.5 11 1 0 11 11 11 7 KH domain SLS PF14611.6 EMR61397.1 - 9.4e-12 45.2 0.1 0.024 14.5 0.0 6.1 2 1 4 6 6 6 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EMR61397.1 - 2.2e-08 33.8 12.5 0.2 11.5 0.1 6.3 5 1 1 6 6 6 3 KH domain KH_4 PF13083.6 EMR61397.1 - 0.016 15.1 0.1 16 5.4 0.0 4.1 3 0 0 3 3 3 0 KH domain BON PF04972.17 EMR61397.1 - 0.11 12.8 1.1 3.5 8.0 0.0 3.4 3 0 0 3 3 3 0 BON domain DUF2067 PF09840.9 EMR61397.1 - 0.48 10.0 10.1 2.1 7.9 0.0 4.9 7 0 0 7 7 7 0 Uncharacterized protein conserved in archaea (DUF2067) DUF5300 PF17224.3 EMR61397.1 - 0.73 10.1 3.2 61 4.0 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5300) PHA_gran_rgn PF09650.10 EMR61397.1 - 0.78 10.0 5.1 56 4.1 0.0 4.2 4 0 0 4 4 4 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Atx10homo_assoc PF09759.9 EMR61398.1 - 1.9e-09 37.4 0.0 4.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain CAP_N PF01213.19 EMR61398.1 - 0.0014 18.2 22.6 0.0079 15.7 0.6 2.7 2 0 0 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CDC27 PF09507.10 EMR61398.1 - 0.0045 16.4 0.0 0.0045 16.4 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 Mito_fiss_reg PF05308.11 EMR61398.1 - 0.32 11.1 19.6 2.8 8.0 0.4 2.7 2 0 0 2 2 2 0 Mitochondrial fission regulator PPP4R2 PF09184.11 EMR61398.1 - 0.92 9.0 12.7 2.5 7.6 12.7 1.7 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 EMR61398.1 - 1.7 8.3 18.6 0.5 10.1 13.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NicO PF03824.16 EMR61398.1 - 3.1 7.1 6.1 4.9 6.4 6.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein ARID PF01388.21 EMR61399.1 - 5.5e-18 65.4 0.2 2.4e-17 63.4 0.1 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 EMR61399.1 - 0.0042 17.7 0.0 0.0094 16.6 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain TFIIA PF03153.13 EMR61399.1 - 0.032 14.3 4.0 0.053 13.5 4.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arm PF00514.23 EMR61399.1 - 0.16 12.1 0.1 8 6.7 0.0 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF5539 PF17693.1 EMR61399.1 - 0.71 9.5 7.4 1.4 8.5 7.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5539) ECM11 PF15463.6 EMR61400.1 - 4e-43 147.2 4.6 4e-43 147.2 4.6 1.9 2 0 0 2 2 2 1 Extracellular mutant protein 11 Utp21 PF04192.12 EMR61401.1 - 3.7e-83 278.6 0.0 5.4e-83 278.1 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EMR61401.1 - 9.2e-16 58.0 25.4 6.8e-06 26.7 0.7 9.9 11 1 0 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR61401.1 - 6e-13 48.9 0.0 0.00054 20.2 0.0 5.7 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EMR61401.1 - 7e-05 21.5 0.0 0.00012 20.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 EMR61401.1 - 0.00013 20.8 0.4 0.57 8.8 0.0 3.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EMR61401.1 - 0.0021 17.1 0.1 0.23 10.3 0.0 2.7 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 EMR61401.1 - 0.15 10.8 0.0 17 4.0 0.0 2.5 1 1 1 2 2 2 0 Nup133 N terminal like Ge1_WD40 PF16529.5 EMR61401.1 - 0.22 10.5 0.1 5.8 5.8 0.0 3.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein His_Phos_2 PF00328.22 EMR61402.1 - 2.6e-111 372.7 0.0 8.4e-111 371.0 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.11 EMR61402.1 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain MFS_1 PF07690.16 EMR61403.1 - 9.4e-36 123.4 48.9 2e-35 122.4 48.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61403.1 - 0.0034 16.3 14.7 0.0034 16.3 14.7 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter Cyto_heme_lyase PF01265.17 EMR61404.1 - 1.6e-32 113.3 0.0 1.9e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase SUIM_assoc PF16619.5 EMR61404.1 - 0.021 14.9 0.2 0.029 14.4 0.2 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MDD_C PF18376.1 EMR61405.1 - 1.5e-64 217.2 0.2 2e-64 216.8 0.2 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EMR61405.1 - 7.1e-09 35.8 2.2 7.1e-09 35.8 2.2 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF2388 PF09498.10 EMR61405.1 - 0.029 14.3 0.4 0.12 12.4 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) Endosulfine PF04667.17 EMR61406.1 - 1.5e-27 95.6 0.2 2.8e-27 94.6 0.2 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region HET PF06985.11 EMR61407.1 - 1.7e-26 93.3 0.9 2.3e-24 86.4 0.9 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ras PF00071.22 EMR61408.1 - 4.7e-18 65.3 0.0 6.6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EMR61408.1 - 0.036 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family TRP PF06011.12 EMR61409.1 - 7.2e-162 538.9 32.5 8.5e-162 538.7 32.5 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EMR61409.1 - 4.6e-32 111.3 0.2 7.7e-32 110.6 0.2 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 EMR61409.1 - 0.00034 21.0 0.0 0.00075 19.9 0.0 1.6 1 0 0 1 1 1 1 ML domain LapA_dom PF06305.11 EMR61409.1 - 5.8 6.8 9.0 0.11 12.4 0.6 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3433 PF11915.8 EMR61410.1 - 6.4e-40 135.5 11.6 9.4e-23 80.5 1.2 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) ABC2_membrane_3 PF12698.7 EMR61410.1 - 0.017 14.2 4.1 0.087 11.9 0.0 3.2 3 1 0 4 4 4 0 ABC-2 family transporter protein AMP-binding PF00501.28 EMR61411.1 - 4.8e-29 101.2 0.0 6.5e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EMR61411.1 - 6.2e-26 91.1 0.0 3.9e-25 88.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EMR61411.1 - 3.2e-12 46.6 0.0 7.4e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EMR61411.1 - 4.5e-07 29.6 0.2 2.5e-06 27.1 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EMR61411.1 - 2.9e-06 28.1 0.2 1.5e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EMR61411.1 - 0.054 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMR61411.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMR61411.1 - 0.11 12.1 0.2 0.17 11.4 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family PS-DH PF14765.6 EMR61412.1 - 5.9e-35 120.9 0.0 1e-34 120.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EMR61412.1 - 4.4e-23 82.1 0.0 1.3e-22 80.6 0.0 1.8 1 1 1 2 2 2 1 KR domain Methyltransf_12 PF08242.12 EMR61412.1 - 3.3e-11 43.8 0.0 7.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR61412.1 - 1.5e-08 35.2 0.0 4.4e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR61412.1 - 4.4e-06 27.3 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR61412.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR61412.1 - 0.0013 19.1 0.0 0.005 17.2 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EMR61412.1 - 0.0022 17.9 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 EMR61412.1 - 0.067 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent RNA_pol_Rpc4 PF05132.14 EMR61412.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Dioxygenase_C PF00775.21 EMR61413.1 - 2.3e-42 144.5 0.0 2.8e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EMR61413.1 - 9.2e-08 31.8 0.0 2.8e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EMR61413.1 - 3.7e-05 23.9 0.0 0.00011 22.4 0.0 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 EMR61413.1 - 0.03 14.3 0.3 0.081 12.9 0.3 1.7 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) Spt5_N PF11942.8 EMR61414.1 - 3.9 8.5 8.2 13 6.8 3.2 3.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Pkinase PF00069.25 EMR61415.1 - 2.2e-52 178.1 0.0 2.8e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR61415.1 - 3.6e-28 98.6 1.0 5.3e-26 91.4 0.1 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR61415.1 - 0.032 13.0 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EMR61415.1 - 0.12 11.7 0.1 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 EMR61416.1 - 1.1e-07 31.5 0.0 9.4e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR61416.1 - 0.0046 16.3 0.0 0.013 14.8 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase zf-LITAF-like PF10601.9 EMR61417.1 - 0.0048 17.1 1.3 0.0065 16.7 1.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain NmrA PF05368.13 EMR61418.1 - 1.4e-28 100.0 0.0 2.1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR61418.1 - 7.9e-25 87.8 0.0 1.2e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding PAC2 PF09754.9 EMR61418.1 - 0.0039 17.2 0.0 0.0064 16.5 0.0 1.3 1 0 0 1 1 1 1 PAC2 family 3Beta_HSD PF01073.19 EMR61418.1 - 0.031 13.3 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Tnp_P_element PF12017.8 EMR61418.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Transposase protein RmlD_sub_bind PF04321.17 EMR61418.1 - 0.067 12.3 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Ima1_N PF09779.9 EMR61419.1 - 1e-31 110.6 0.4 2.2e-31 109.5 0.4 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 EMR61419.1 - 0.27 11.3 2.9 8.7 6.5 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon PyrI_C PF02748.15 EMR61419.1 - 2.1 8.3 4.3 14 5.7 0.3 2.5 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_Tnp_IS1595 PF12760.7 EMR61419.1 - 4.7 7.3 5.9 1.4 8.9 2.4 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain NACHT PF05729.12 EMR61420.1 - 4.7e-07 29.9 0.0 6.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMR61420.1 - 6.6e-06 26.6 0.0 8.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR61420.1 - 0.00055 20.2 0.0 0.00086 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 EMR61420.1 - 0.015 14.6 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_18 PF13238.6 EMR61420.1 - 0.021 15.4 0.2 0.042 14.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EMR61420.1 - 0.039 13.6 0.1 0.12 11.9 0.1 1.8 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EMR61420.1 - 0.045 13.8 0.0 1 9.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EMR61420.1 - 0.047 14.1 0.1 0.074 13.5 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EMR61420.1 - 0.073 12.4 0.1 0.11 11.8 0.1 1.3 1 1 0 1 1 1 0 KaiC Torsin PF06309.11 EMR61420.1 - 0.083 13.0 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 EMR61420.1 - 0.094 13.2 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 EMR61420.1 - 0.096 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EMR61420.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain ExbD PF02472.16 EMR61420.1 - 0.12 12.5 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR AAA_17 PF13207.6 EMR61420.1 - 0.14 12.6 0.2 0.25 11.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMR61420.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain Alg14 PF08660.11 EMR61421.1 - 2.9e-41 141.3 0.0 4.1e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Angiomotin_C PF12240.8 EMR61421.1 - 0.034 13.7 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Angiomotin C terminal Ank_2 PF12796.7 EMR61422.1 - 1.7e-33 115.1 1.0 3.2e-11 43.7 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR61422.1 - 1.6e-21 76.3 0.1 2e-07 31.4 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR61422.1 - 6e-21 72.3 0.2 0.00028 21.1 0.0 7.2 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 EMR61422.1 - 4.2e-20 71.2 0.3 5.4e-06 26.6 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EMR61422.1 - 1.1e-16 60.7 1.2 0.0061 16.8 0.1 5.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 EMR61422.1 - 0.042 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) U3_snoRNA_assoc PF08297.11 EMR61423.1 - 3.6e-15 56.4 2.3 3.6e-15 56.4 2.3 4.2 3 1 1 4 4 4 1 U3 snoRNA associated PH_4 PF15404.6 EMR61423.1 - 0.24 11.2 2.2 0.67 9.7 2.2 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain GCV_T PF01571.21 EMR61424.1 - 3.8e-05 23.2 0.0 6.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain PH_10 PF15411.6 EMR61425.1 - 9e-29 100.2 0.1 1.4e-28 99.6 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EMR61425.1 - 1.6e-14 54.5 0.0 2.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EMR61425.1 - 1.7e-10 41.1 0.1 9e-10 38.7 0.1 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain PH PF00169.29 EMR61425.1 - 0.082 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF1147 PF06615.11 EMR61425.1 - 0.12 12.5 0.5 0.29 11.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) NAD_synthase PF02540.17 EMR61425.1 - 0.16 11.0 0.0 0.82 8.7 0.0 1.9 2 0 0 2 2 2 0 NAD synthase Peptidase_A3 PF02160.15 EMR61425.1 - 0.21 11.0 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Hat1_N PF10394.9 EMR61426.1 - 3.4e-46 157.4 0.0 6.1e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EMR61426.1 - 0.017 15.3 0.0 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR61426.1 - 0.19 11.7 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PTPLA PF04387.14 EMR61427.1 - 1e-54 184.7 8.8 1.6e-54 184.1 8.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Tmem26 PF09772.9 EMR61427.1 - 0.058 12.7 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 26 Pkinase PF00069.25 EMR61428.1 - 1.5e-53 181.9 0.0 1.9e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR61428.1 - 1.2e-34 119.7 0.0 1.6e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR61428.1 - 9.3e-06 25.2 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMR61428.1 - 0.0021 16.9 0.0 0.003 16.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EMR61428.1 - 0.13 11.9 0.0 6.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Amastin PF07344.11 EMR61429.1 - 0.19 11.6 2.3 0.25 11.2 1.1 1.7 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF1011 PF06237.12 EMR61429.1 - 8.5 6.8 6.4 6.7 7.1 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1011) DIOX_N PF14226.6 EMR61430.1 - 2.1e-23 83.3 0.0 3.3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR61430.1 - 1.3e-17 64.1 0.0 2.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SDA1 PF05285.12 EMR61431.1 - 0.052 13.0 10.1 0.063 12.7 10.1 1.1 1 0 0 1 1 1 0 SDA1 CBF PF03914.17 EMR61431.1 - 0.081 13.0 2.2 0.12 12.4 2.2 1.2 1 0 0 1 1 1 0 CBF/Mak21 family DNA_pol_phi PF04931.13 EMR61431.1 - 0.11 10.6 11.1 0.12 10.4 11.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EMR61431.1 - 0.24 9.6 8.3 0.28 9.4 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoVR PF04293.13 EMR61431.1 - 0.74 8.4 4.4 1 8.0 4.4 1.1 1 0 0 1 1 1 0 SpoVR like protein Ribosomal_L37ae PF01780.19 EMR61432.1 - 1.5e-37 127.5 9.5 1.7e-37 127.4 9.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EMR61432.1 - 0.0011 19.1 1.9 0.0015 18.7 1.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1364 PF07102.12 EMR61432.1 - 0.042 13.7 0.4 0.06 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Abhydrolase_6 PF12697.7 EMR61433.1 - 5e-07 30.6 5.3 5.4e-07 30.4 4.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EMR61433.1 - 3.1e-05 23.6 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EMR61433.1 - 0.00046 20.0 0.1 0.00085 19.1 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EMR61433.1 - 0.011 15.1 0.6 0.019 14.2 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EMR61433.1 - 0.019 14.9 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 EMR61433.1 - 0.028 14.2 0.0 0.084 12.7 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EMR61433.1 - 0.037 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EMR61433.1 - 0.04 14.0 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain TPR_19 PF14559.6 EMR61434.1 - 0.0021 18.5 0.2 0.052 14.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Cyclin_C_2 PF16899.5 EMR61434.1 - 0.043 14.2 0.1 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 Cyclin C-terminal domain TPR_6 PF13174.6 EMR61434.1 - 0.044 14.4 0.6 5.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR61434.1 - 0.12 12.6 0.5 0.86 9.9 0.3 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EMR61434.1 - 5 8.2 8.7 34 5.6 0.3 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Sacchrp_dh_NADP PF03435.18 EMR61435.1 - 6.5e-15 55.5 0.0 1e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EMR61435.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Amidohydro_2 PF04909.14 EMR61436.1 - 1.5e-26 93.9 0.0 2.5e-26 93.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 EMR61436.1 - 0.16 11.4 0.0 0.76 9.1 0.0 1.9 2 0 0 2 2 2 0 TatD related DNase GTP_EFTU PF00009.27 EMR61437.1 - 2.2e-57 193.8 0.0 3.8e-57 193.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EMR61437.1 - 6.3e-16 58.2 0.0 1.8e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMR61437.1 - 6.7e-09 36.0 0.0 1.8e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EMR61437.1 - 1.2e-08 34.9 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EMR61437.1 - 6.1e-05 22.8 0.0 0.026 14.3 0.0 3.3 3 1 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EMR61437.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ribosomal_L30_N PF08079.12 EMR61438.1 - 8.3e-26 90.0 17.6 1.4e-25 89.3 17.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EMR61438.1 - 3.7e-17 61.9 2.2 9.5e-17 60.6 2.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S11 PF00411.19 EMR61439.1 - 4e-46 156.0 1.3 4.9e-46 155.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EMR61439.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Cpn60_TCP1 PF00118.24 EMR61440.1 - 8e-150 499.7 12.1 9e-150 499.5 12.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2204 PF09970.9 EMR61440.1 - 0.083 12.5 1.6 7.6 6.1 0.0 3.3 3 1 1 4 4 4 0 Nucleotidyl transferase of unknown function (DUF2204) Fe-S_biosyn PF01521.20 EMR61441.1 - 1.3e-11 44.7 0.0 4.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Clathrin-link PF09268.10 EMR61441.1 - 0.15 11.5 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Clathrin, heavy-chain linker PRCC PF10253.9 EMR61441.1 - 1.9 9.2 11.4 2.8 8.7 11.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SPX PF03105.19 EMR61441.1 - 2.7 7.8 7.8 3.3 7.5 7.8 1.3 1 0 0 1 1 1 0 SPX domain Hamartin PF04388.12 EMR61441.1 - 3.8 6.1 9.3 3.9 6.0 9.3 1.0 1 0 0 1 1 1 0 Hamartin protein Glyco_hydro_18 PF00704.28 EMR61442.1 - 2.1e-11 44.2 0.1 2.6e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.32 EMR61443.1 - 3.8e-37 125.6 26.8 4e-08 33.8 0.3 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EMR61443.1 - 1.3e-12 47.4 0.9 3.2e-12 46.2 0.9 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EMR61443.1 - 1.9e-11 44.1 2.8 0.13 12.6 0.0 6.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR61443.1 - 2.6e-08 33.0 7.3 0.059 12.0 0.1 6.2 2 1 5 7 7 7 4 Nucleoporin Nup120/160 F-box PF00646.33 EMR61443.1 - 1.7e-06 27.8 2.4 3.5e-06 26.7 2.4 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 EMR61443.1 - 0.00018 20.9 0.0 0.013 14.8 0.0 2.7 1 1 3 4 4 4 2 WD40-like domain BBS2_Mid PF14783.6 EMR61443.1 - 0.0025 17.9 0.1 0.73 9.9 0.0 3.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 EMR61443.1 - 0.0029 17.2 7.5 0.0051 16.4 2.6 2.7 2 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 EMR61443.1 - 0.0064 16.9 5.3 5.3 7.7 0.0 5.4 6 0 0 6 6 6 1 PQQ-like domain Mcl1_mid PF12341.8 EMR61443.1 - 0.052 12.9 0.7 1.3 8.3 0.7 2.3 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region AMP-binding PF00501.28 EMR61444.1 - 1.1e-58 198.8 0.0 1.6e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EMR61444.1 - 9e-12 45.2 0.0 2.2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 EMR61444.1 - 3.3e-10 39.3 2.1 0.0097 15.6 1.4 5.5 6 0 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMR61444.1 - 0.008 15.9 10.9 0.017 14.8 0.6 4.3 5 0 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase Ribosomal_L12 PF00542.19 EMR61445.1 - 5.9e-22 77.8 3.5 9.5e-22 77.1 3.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EMR61445.1 - 0.0074 16.0 6.9 0.0074 16.0 6.9 2.9 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 EMR61445.1 - 8.6 7.0 14.2 0.75 10.4 7.5 2.3 1 1 1 2 2 2 0 60s Acidic ribosomal protein Arylsulfotran_2 PF14269.6 EMR61446.1 - 5.3e-109 364.2 1.2 6.2e-109 364.0 1.2 1.0 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMR61446.1 - 7.9e-12 44.8 0.2 3e-10 39.6 0.2 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Paf67 PF10255.9 EMR61447.1 - 5.6e-156 519.6 0.2 6.7e-156 519.3 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EMR61447.1 - 0.041 14.0 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat VWA_2 PF13519.6 EMR61448.1 - 0.013 16.1 0.0 0.048 14.3 0.0 2.0 1 0 0 1 1 1 0 von Willebrand factor type A domain HMG_box PF00505.19 EMR61449.1 - 3.4e-06 27.4 5.4 3.4e-06 27.4 5.4 2.9 2 1 1 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR61449.1 - 5.6e-06 26.9 2.2 5.6e-06 26.9 2.2 2.1 2 1 0 2 2 2 1 HMG-box domain bZIP_1 PF00170.21 EMR61449.1 - 0.0096 16.0 1.5 0.0096 16.0 1.5 2.9 3 0 0 3 3 3 1 bZIP transcription factor LCD1 PF09798.9 EMR61449.1 - 0.22 10.0 0.6 0.31 9.5 0.6 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein KfrA_N PF11740.8 EMR61449.1 - 0.45 11.2 8.9 6.2 7.5 2.7 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DnaJ PF00226.31 EMR61450.1 - 2.1e-14 53.4 0.2 5.3e-14 52.1 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain SNF2_N PF00176.23 EMR61451.1 - 2.3e-63 214.0 0.0 4e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR61451.1 - 3.6e-20 72.4 0.0 8.4e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR61451.1 - 3.1e-06 27.3 0.0 8.8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMR61452.1 - 1.6e-39 135.5 0.0 4.5e-39 134.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR61452.1 - 2.2e-30 105.2 0.0 6.3e-30 103.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR61452.1 - 1.3e-05 25.3 0.0 2.9e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EMR61452.1 - 0.0055 15.5 0.0 0.0093 14.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 EMR61452.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF5549 PF17703.1 EMR61452.1 - 0.22 11.1 1.3 0.77 9.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5549) SEEEED PF14797.6 EMR61453.1 - 0.81 9.9 24.5 0.43 10.8 7.8 2.4 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex CTK3 PF12243.8 EMR61454.1 - 7.6e-46 155.1 0.8 1.1e-45 154.6 0.8 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EMR61454.1 - 4.7e-18 65.1 9.1 4.7e-18 65.1 9.1 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus BAR_3_WASP_bdg PF10456.9 EMR61454.1 - 0.0065 16.0 4.2 0.74 9.2 2.6 2.1 2 0 0 2 2 2 2 WASP-binding domain of Sorting nexin protein Rcd1 PF04078.13 EMR61454.1 - 0.041 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like DUF155 PF02582.14 EMR61455.1 - 9.6e-53 178.9 0.1 1.3e-52 178.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 P5CR_dimer PF14748.6 EMR61456.1 - 1.5e-16 60.5 2.0 2.9e-16 59.6 2.0 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EMR61456.1 - 8.2e-11 42.3 0.2 2.1e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Cpn10 PF00166.21 EMR61457.1 - 4.7e-29 100.3 0.0 5.3e-29 100.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Svf1_C PF17187.4 EMR61458.1 - 2.3e-62 209.7 0.2 5.4e-62 208.5 0.0 1.7 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EMR61458.1 - 6.7e-55 185.6 0.0 9.7e-55 185.1 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain KH_4 PF13083.6 EMR61458.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 KH domain Glyco_hydro_61 PF03443.14 EMR61459.1 - 1.9e-53 181.4 0.1 8.2e-53 179.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 HTH_29 PF13551.6 EMR61459.1 - 0.19 11.8 0.3 0.44 10.6 0.3 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Spo7 PF03907.13 EMR61460.1 - 1.7e-95 318.7 0.0 2.3e-95 318.3 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Pyr_redox_2 PF07992.14 EMR61461.1 - 1.8e-32 112.8 3.1 2.3e-32 112.4 3.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR61461.1 - 2.1e-11 44.2 1.7 7.8e-09 36.0 1.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR61461.1 - 0.0002 20.6 1.3 0.0015 17.8 0.6 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EMR61461.1 - 0.00075 19.2 7.6 0.95 9.0 0.8 3.7 2 2 1 3 3 3 3 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR61461.1 - 0.0014 17.8 0.4 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMR61461.1 - 0.0032 17.5 0.8 2.6 8.0 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Tricorn_PDZ PF14685.6 EMR61461.1 - 0.025 14.6 1.8 0.098 12.6 0.1 2.5 3 0 0 3 3 3 0 Tricorn protease PDZ domain Pyr_redox_3 PF13738.6 EMR61461.1 - 0.03 13.6 1.3 0.1 11.8 0.5 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR61461.1 - 0.032 14.5 0.3 1.2 9.4 0.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SNF2_N PF00176.23 EMR61462.1 - 3.9e-70 236.3 0.0 5.6e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR61462.1 - 2.9e-14 53.3 0.0 8.2e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 EMR61462.1 - 3.4e-09 36.9 3.9 3.4e-09 36.9 3.9 2.5 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EMR61462.1 - 1.8e-07 31.0 1.8 5.4e-07 29.5 1.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMR61462.1 - 3e-07 30.2 3.7 7.4e-07 28.9 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMR61462.1 - 1.1e-06 28.5 3.3 2.9e-06 27.1 3.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMR61462.1 - 1.5e-06 27.9 4.1 5e-06 26.3 4.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HIRAN PF08797.11 EMR61462.1 - 5.4e-06 26.2 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-rbx1 PF12678.7 EMR61462.1 - 1.9e-05 24.9 4.3 5.8e-05 23.3 4.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EMR61462.1 - 2.4e-05 24.3 2.1 6.4e-05 22.9 2.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EMR61462.1 - 4.4e-05 23.3 1.5 4.4e-05 23.3 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMR61462.1 - 0.00046 19.9 5.3 0.0013 18.5 5.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EMR61462.1 - 0.00079 19.5 2.5 0.0017 18.5 2.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EMR61462.1 - 0.0037 17.1 3.0 0.011 15.6 3.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EMR61462.1 - 0.0043 16.8 2.5 0.0056 16.5 1.4 1.7 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EMR61462.1 - 0.074 13.2 3.4 0.19 11.9 3.4 1.7 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 EMR61462.1 - 0.22 11.2 2.2 0.52 10.0 2.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EMR61462.1 - 1.2 9.3 5.2 0.36 11.0 1.9 1.9 2 0 0 2 2 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EMR61462.1 - 6 6.8 7.7 0.67 9.8 2.6 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L11 PF00298.19 EMR61463.1 - 6.5e-27 93.8 0.4 1.1e-26 93.1 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EMR61463.1 - 8.5e-27 92.8 0.1 1.5e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain CDO_I PF05995.12 EMR61464.1 - 4.3e-43 146.5 0.0 4.9e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I Abhydrolase_1 PF00561.20 EMR61466.1 - 5.7e-21 75.3 0.0 6.2e-20 71.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR61466.1 - 1.2e-15 57.4 0.0 2.5e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR61466.1 - 6.4e-15 56.4 0.0 2.1e-14 54.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EMR61466.1 - 3.5e-05 23.3 0.0 0.00013 21.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EMR61466.1 - 8e-05 22.4 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EMR61466.1 - 0.0045 17.1 0.1 0.028 14.6 0.1 2.1 1 1 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 EMR61466.1 - 0.019 14.5 0.0 0.089 12.3 0.0 2.0 2 1 1 3 3 3 0 Lipid-droplet associated hydrolase Chlorophyllase PF07224.11 EMR61466.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 EMR61466.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Cation_ATPase_N PF00690.26 EMR61466.1 - 0.064 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DLH PF01738.18 EMR61466.1 - 0.072 12.6 0.0 11 5.6 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EMR61466.1 - 0.081 12.7 0.0 23 4.7 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 EMR61466.1 - 0.089 12.5 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EMR61466.1 - 0.098 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EMR61466.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) adh_short_C2 PF13561.6 EMR61467.1 - 4.2e-44 150.9 0.7 5.1e-44 150.6 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR61467.1 - 7.7e-33 113.6 2.0 1e-32 113.2 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR61467.1 - 6.8e-05 22.9 0.4 9.6e-05 22.4 0.4 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 EMR61467.1 - 0.0017 18.3 0.2 0.0025 17.7 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.19 EMR61467.1 - 0.0058 16.0 0.3 0.014 14.8 0.2 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_deac_2 PF04748.13 EMR61467.1 - 0.024 13.8 0.1 0.043 13.0 0.1 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase 3HCDH_N PF02737.18 EMR61467.1 - 0.058 13.3 0.2 0.094 12.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 EMR61467.1 - 0.09 12.3 1.1 0.28 10.7 1.0 1.8 2 0 0 2 2 2 0 NmrA-like family GFO_IDH_MocA PF01408.22 EMR61467.1 - 0.11 13.4 0.3 0.19 12.6 0.3 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold End3 PF12761.7 EMR61468.1 - 2.9e-78 262.6 3.1 3.8e-78 262.2 3.1 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EMR61468.1 - 3.8e-47 158.5 0.0 7.8e-46 154.3 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EMR61468.1 - 1.5e-06 27.3 0.2 1.5e-06 27.3 0.2 2.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EMR61468.1 - 2.3e-05 24.8 0.6 0.00011 22.6 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EMR61468.1 - 0.0019 18.0 0.1 0.0043 16.9 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EMR61468.1 - 0.0034 17.2 0.7 0.012 15.5 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EMR61468.1 - 0.044 13.3 3.6 0.059 12.9 0.1 2.6 2 0 0 2 2 2 0 EF hand CSN5_C PF18323.1 EMR61468.1 - 0.053 14.4 1.1 0.16 12.9 1.1 1.8 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DSPc PF00782.20 EMR61469.1 - 1e-13 51.2 0.1 2e-13 50.3 0.1 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EMR61469.1 - 0.18 12.1 0.0 0.37 11.1 0.0 1.7 1 1 0 1 1 1 0 Rit1 DUSP-like domain RNase_H PF00075.24 EMR61470.1 - 7e-21 74.9 0.0 9e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EMR61470.1 - 1.1e-05 25.2 0.9 0.01 15.6 0.9 2.9 1 1 0 1 1 1 1 Reverse transcriptase-like DUF736 PF05284.12 EMR61471.1 - 0.082 12.8 0.7 2.3 8.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF736) ATP-synt_8 PF00895.20 EMR61471.1 - 0.096 13.2 1.0 0.15 12.5 1.0 1.3 1 0 0 1 1 1 0 ATP synthase protein 8 Velvet PF11754.8 EMR61473.1 - 1.1e-16 61.5 0.3 2.4e-07 30.9 0.1 2.1 2 0 0 2 2 2 2 Velvet factor RhoGEF PF00621.20 EMR61474.1 - 5.9e-31 108.1 0.0 5.9e-31 108.1 0.0 2.6 2 1 0 2 2 2 1 RhoGEF domain Reprolysin_2 PF13574.6 EMR61474.1 - 0.11 12.4 0.2 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Acetyltransf_1 PF00583.25 EMR61475.1 - 4.2e-06 27.0 0.0 7.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMR61475.1 - 4.2e-06 26.6 0.0 7.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EMR61475.1 - 0.02 15.6 0.0 0.041 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EMR61475.1 - 0.054 12.9 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_10 PF13673.7 EMR61475.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 EMR61475.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_7 PF13508.7 EMR61475.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR61475.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3602 PF12223.8 EMR61476.1 - 3e-16 59.8 12.1 2.7e-13 50.3 1.0 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) URO-D PF01208.17 EMR61477.1 - 6.3e-122 407.0 0.0 7.1e-122 406.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Zn_clus PF00172.18 EMR61478.1 - 1.4e-08 34.7 8.0 2.7e-08 33.8 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR61478.1 - 9.5e-07 28.1 0.1 2.4e-06 26.8 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain BCMA-Tall_bind PF09257.10 EMR61478.1 - 0.98 9.6 5.4 2.8 8.1 5.4 1.7 1 0 0 1 1 1 0 BCMA, TALL-1 binding AAA_18 PF13238.6 EMR61479.1 - 3.3e-28 98.8 0.1 1.6e-27 96.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EMR61479.1 - 8.5e-08 32.7 0.0 3.3e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 EMR61479.1 - 1.1e-05 25.6 0.0 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.6 EMR61479.1 - 1.5e-05 25.2 0.0 0.0089 16.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMR61479.1 - 1.5e-05 25.3 0.3 9.2e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EMR61479.1 - 1.5e-05 25.4 0.0 0.00044 20.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 EMR61479.1 - 0.00049 19.8 0.2 0.48 10.1 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase SKI PF01202.22 EMR61479.1 - 0.00077 19.6 0.1 0.0098 16.0 0.1 2.0 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.15 EMR61479.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.6 EMR61479.1 - 0.0012 19.2 0.1 0.0048 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 EMR61479.1 - 0.0015 18.4 0.2 1.3 8.8 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase Hydin_ADK PF17213.3 EMR61479.1 - 0.0021 18.4 0.0 0.0045 17.3 0.0 1.6 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_5 PF07728.14 EMR61479.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.6 EMR61479.1 - 0.014 15.5 0.0 0.05 13.7 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_16 PF13191.6 EMR61479.1 - 0.015 15.6 0.1 0.021 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 EMR61479.1 - 0.02 14.7 0.4 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 EMR61479.1 - 0.022 15.1 0.1 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EMR61479.1 - 0.027 13.9 0.0 0.079 12.4 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 EMR61479.1 - 0.027 14.2 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EMR61479.1 - 0.043 13.5 1.2 0.95 9.1 0.4 2.2 1 1 1 2 2 2 0 AAA domain MeaB PF03308.16 EMR61479.1 - 0.058 12.4 0.2 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EMR61479.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR61479.1 - 0.063 13.7 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 1 0 RNA helicase Viral_helicase1 PF01443.18 EMR61479.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EMR61479.1 - 0.15 12.6 0.1 0.61 10.6 0.1 1.9 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 EMR61479.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 EMR61479.1 - 0.19 11.1 0.1 0.35 10.2 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NAP PF00956.18 EMR61480.1 - 1.1e-101 339.5 8.2 1.1e-101 339.5 8.2 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Ham1p_like PF01725.16 EMR61481.1 - 1e-57 195.1 0.0 1.2e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family 2-Hacid_dh_C PF02826.19 EMR61482.1 - 6.8e-54 181.9 0.0 1e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR61482.1 - 5.7e-35 119.9 0.1 8.4e-35 119.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMR61482.1 - 0.00011 22.4 0.5 0.00025 21.2 0.5 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EMR61482.1 - 0.00021 21.4 0.6 0.00055 20.0 0.1 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 EMR61482.1 - 0.00043 19.9 0.3 0.02 14.5 0.1 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EMR61482.1 - 0.024 15.2 0.2 0.18 12.3 0.1 2.4 2 1 0 2 2 2 0 XdhC Rossmann domain ACT PF01842.25 EMR61482.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 ACT domain Amdase PF17645.1 EMR61482.1 - 0.055 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Arylmalonate decarboxylase 3HCDH_N PF02737.18 EMR61482.1 - 0.22 11.4 1.1 1.9 8.4 0.7 2.4 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Myosin_head PF00063.21 EMR61483.1 - 5.4e-260 864.3 0.1 9.6e-260 863.5 0.1 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EMR61483.1 - 1.9e-26 92.4 2.6 1.9e-26 92.4 2.6 2.6 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 EMR61483.1 - 2.1e-11 42.5 33.7 0.00022 20.7 0.6 7.3 7 0 0 7 7 7 5 IQ calmodulin-binding motif GAS PF13851.6 EMR61483.1 - 4.8e-05 22.8 33.7 0.00054 19.4 18.2 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EMR61483.1 - 0.0097 14.8 24.7 0.029 13.2 24.7 1.9 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_22 PF13401.6 EMR61483.1 - 0.018 15.3 0.0 0.087 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 EMR61483.1 - 0.019 14.8 5.3 0.02 14.7 3.0 2.2 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain AAA_13 PF13166.6 EMR61483.1 - 0.021 13.5 18.2 0.045 12.4 18.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR61483.1 - 0.025 15.0 0.1 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 EMR61483.1 - 0.1 12.6 0.0 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 EMR61483.1 - 0.12 12.5 0.7 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain CENP-F_leu_zip PF10473.9 EMR61483.1 - 0.32 11.0 32.6 2.7 8.0 17.0 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.11 EMR61483.1 - 0.44 9.4 27.9 0.77 8.6 27.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 EMR61483.1 - 0.46 10.5 8.9 2.7 8.0 8.9 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 EMR61483.1 - 0.68 10.2 24.3 0.24 11.7 11.3 3.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Sec34 PF04136.15 EMR61483.1 - 4.3 7.2 15.6 0.52 10.2 6.3 2.8 1 1 1 2 2 2 0 Sec34-like family Noelin-1 PF12308.8 EMR61483.1 - 5.5 7.0 11.5 3.1 7.8 2.4 3.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein KASH_CCD PF14662.6 EMR61483.1 - 5.9 6.7 36.3 0.72 9.6 8.1 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 EMR61483.1 - 7.2 5.8 28.8 9.2 5.5 16.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GMC_oxred_N PF00732.19 EMR61484.1 - 1.6e-49 168.9 0.0 2.3e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR61484.1 - 1.9e-39 135.4 0.0 3.1e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR61484.1 - 2.4e-07 30.2 0.1 0.0074 15.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EMR61484.1 - 4.2e-06 26.1 0.0 6.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMR61484.1 - 1.5e-05 25.2 0.1 0.00011 22.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR61484.1 - 6.6e-05 22.3 0.0 0.0014 17.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR61484.1 - 7e-05 22.6 0.1 0.0012 18.5 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR61484.1 - 0.00096 19.7 0.1 0.17 12.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR61484.1 - 0.012 15.0 0.1 0.98 8.7 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR61484.1 - 0.014 14.2 0.2 0.038 12.9 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 EMR61484.1 - 0.025 13.3 0.1 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein DEAD PF00270.29 EMR61485.1 - 5e-50 169.7 0.2 2.9e-48 163.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EMR61485.1 - 8.1e-24 83.6 0.0 1.9e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EMR61485.1 - 8.6e-22 77.6 0.0 2.6e-21 76.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR61485.1 - 9.3e-07 29.0 2.1 2.5e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Aldedh PF00171.22 EMR61486.1 - 1.4e-150 501.8 0.1 1.8e-150 501.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mersacidin PF16934.5 EMR61486.1 - 5.4 6.9 6.6 0.78 9.5 0.3 2.5 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) Anoctamin PF04547.12 EMR61487.1 - 8e-98 328.2 1.4 9.7e-98 327.9 1.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PAPS_reduct PF01507.19 EMR61488.1 - 9.5e-30 103.9 0.0 2.7e-29 102.4 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Sad1_UNC PF07738.13 EMR61489.1 - 6.5e-07 29.4 0.3 1.3e-05 25.2 0.3 2.2 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Baculo_PEP_C PF04513.12 EMR61489.1 - 0.0019 18.3 0.1 0.0039 17.2 0.1 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 EMR61489.1 - 0.0019 16.9 0.6 0.0026 16.5 0.6 1.1 1 0 0 1 1 1 1 AAA domain ApoLp-III PF07464.11 EMR61489.1 - 0.011 15.9 3.2 0.02 15.0 1.7 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Erp_C PF06780.11 EMR61489.1 - 0.025 14.6 2.7 0.028 14.4 1.5 1.8 1 1 0 1 1 1 0 Erp protein C-terminus Sun2_CC2 PF18580.1 EMR61489.1 - 0.15 12.3 0.2 5.5 7.3 0.0 3.1 3 1 0 3 3 3 0 SUN2 coiled coil domain 2 RAC_head PF16717.5 EMR61489.1 - 1.9 9.5 5.7 0.64 11.0 1.3 2.4 2 1 1 3 3 3 0 Ribosome-associated complex head domain MgtE_N PF03448.17 EMR61490.1 - 0.00093 19.8 1.2 0.031 14.9 1.2 2.3 1 1 0 1 1 1 1 MgtE intracellular N domain NAAA-beta PF15508.6 EMR61490.1 - 0.0045 17.3 0.6 6.3 7.2 0.6 3.4 1 1 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MBOAT_2 PF13813.6 EMR61490.1 - 0.0053 17.0 9.1 66 3.9 9.1 3.4 1 1 0 1 1 1 0 Membrane bound O-acyl transferase family DUF2884 PF11101.8 EMR61490.1 - 0.018 14.5 7.5 0.66 9.5 7.5 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) DUF697 PF05128.12 EMR61490.1 - 0.02 14.6 2.2 3.3 7.4 2.2 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF697) Peroxin-3 PF04882.12 EMR61490.1 - 0.026 13.5 13.3 3.7e+02 -0.1 13.3 2.9 1 1 0 1 1 1 0 Peroxin-3 7TMR-HDED PF07697.11 EMR61490.1 - 0.6 10.2 5.4 0.99 9.5 5.4 1.3 1 0 0 1 1 1 0 7TM-HD extracellular JHBP PF06585.11 EMR61490.1 - 1.1 8.4 13.0 4.7 6.3 3.3 2.7 1 1 1 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) TrbL PF04610.14 EMR61490.1 - 1.3 8.7 14.3 11 5.7 6.3 2.5 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Mob1_phocein PF03637.17 EMR61490.1 - 1.5 8.8 5.6 24 4.9 5.7 2.3 1 1 0 1 1 1 0 Mob1/phocein family DnaG_DnaB_bind PF08278.11 EMR61490.1 - 1.6 9.4 10.1 1.1e+02 3.4 10.1 3.3 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding Vut_1 PF02592.15 EMR61490.1 - 2.4 8.5 14.4 16 5.8 14.4 2.0 1 1 0 1 1 1 0 Putative vitamin uptake transporter FWWh PF14922.6 EMR61490.1 - 4 7.4 13.5 6.7 6.6 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function GDP_Man_Dehyd PF16363.5 EMR61491.1 - 4.8e-49 167.6 0.0 7.2e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMR61491.1 - 9.6e-48 162.7 0.0 1.2e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR61491.1 - 1.7e-18 66.6 0.0 1.2e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMR61491.1 - 4.2e-13 49.1 0.0 4.8e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMR61491.1 - 1.2e-10 41.0 0.0 1.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EMR61491.1 - 6e-07 29.1 0.0 9.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EMR61491.1 - 1.9e-06 27.3 0.0 0.00014 21.1 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EMR61491.1 - 1e-05 25.5 0.0 2e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR61491.1 - 0.00086 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 EMR61491.1 - 0.0031 17.1 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 EMR61491.1 - 0.01 15.4 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.6 EMR61491.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 EMR61491.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAC PF01849.18 EMR61492.1 - 4e-07 29.9 0.3 8.1e-07 28.9 0.1 1.5 2 0 0 2 2 2 1 NAC domain FAM176 PF14851.6 EMR61493.1 - 0.066 12.9 0.9 0.89 9.2 2.4 1.8 2 0 0 2 2 2 0 FAM176 family S-antigen PF05756.11 EMR61493.1 - 0.5 10.8 6.2 1.1 9.7 6.2 1.6 1 0 0 1 1 1 0 S-antigen protein DNA_pol_phi PF04931.13 EMR61493.1 - 0.5 8.4 10.5 0.7 7.9 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EMR61493.1 - 1.2 7.3 7.8 1.2 7.3 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 EMR61493.1 - 1.6 7.8 4.4 2 7.5 4.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ANAPC15 PF15243.6 EMR61493.1 - 4.3 7.8 11.9 9.9 6.6 11.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF4637 PF15470.6 EMR61493.1 - 5.5 6.7 7.9 44 3.7 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) NOA36 PF06524.12 EMR61493.1 - 5.6 6.2 10.0 0.98 8.7 6.8 1.3 2 0 0 2 2 2 0 NOA36 protein Fungus-induced PF10917.8 EMR61493.1 - 8.2 6.8 11.2 19 5.7 0.1 2.4 2 0 0 2 2 2 0 Fungus-induced protein EPSP_synthase PF00275.20 EMR61494.1 - 9.3e-133 442.9 0.0 1.4e-132 442.3 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EMR61494.1 - 1.7e-101 338.8 0.0 2.6e-101 338.2 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EMR61494.1 - 6.7e-59 199.9 0.0 1.7e-58 198.6 0.0 1.7 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 EMR61494.1 - 3.7e-38 131.1 0.0 2.3e-36 125.3 0.0 2.7 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 EMR61494.1 - 7.3e-24 83.8 0.0 2.1e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EMR61494.1 - 1e-08 35.2 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 EMR61494.1 - 5e-06 26.2 0.1 1.9e-05 24.3 0.1 2.1 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EMR61494.1 - 0.00022 21.3 0.0 0.00076 19.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SRP54 PF00448.22 EMR61494.1 - 0.096 12.3 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EMR61494.1 - 0.11 12.9 0.1 0.92 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain T6SS_VipA PF05591.12 EMR61494.1 - 0.14 11.9 0.1 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 Histone PF00125.24 EMR61495.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EMR61495.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EMR61495.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EMR61495.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EMR61495.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EMR61495.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EMR61495.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DEAD_2 PF06733.15 EMR61496.1 - 1.8e-56 190.6 0.1 3.4e-56 189.6 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EMR61496.1 - 4.1e-48 163.6 2.1 1.9e-44 151.6 0.6 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EMR61496.1 - 6.8e-43 146.8 0.0 5e-42 144.0 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 EMR61496.1 - 0.00013 22.0 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMR61496.1 - 0.00046 20.0 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 EMR61496.1 - 0.011 14.5 0.0 0.21 10.2 0.0 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain UvrD_C PF13361.6 EMR61496.1 - 0.015 14.7 0.4 0.029 13.7 0.4 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EMR61496.1 - 0.044 14.1 0.1 4.6 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EMR61496.1 - 0.047 12.9 0.0 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EMR61496.1 - 0.12 11.8 0.0 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 EMR61496.1 - 7.9 6.2 7.2 0.81 9.4 1.4 2.2 2 1 0 2 2 2 0 AAA domain RNA_pol_Rpb1_5 PF04998.17 EMR61498.1 - 7.2e-89 297.8 0.0 2.5e-88 296.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMR61498.1 - 4e-68 228.8 0.2 9.8e-68 227.6 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EMR61498.1 - 1e-29 103.5 0.0 3.4e-29 101.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EMR61498.1 - 2e-17 63.1 0.0 8.5e-17 61.1 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 EMR61498.1 - 1.1e-12 47.9 1.8 1e-10 41.5 1.8 3.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 PRP3 PF08572.10 EMR61499.1 - 1.2e-75 254.1 4.8 1.8e-75 253.5 4.8 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EMR61499.1 - 6.4e-43 146.3 0.0 6.4e-43 146.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) GET2 PF08690.10 EMR61499.1 - 1.4 8.5 8.6 0.037 13.7 1.9 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 CENP-T_C PF15511.6 EMR61500.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EMR61500.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EMR61500.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EMR61500.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EMR61500.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EMR61500.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EMR61500.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EMR61500.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EMR61500.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region AMP-binding PF00501.28 EMR61501.1 - 2.4e-70 237.3 0.0 2e-69 234.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EMR61501.1 - 4.3e-63 212.9 0.0 6.4e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EMR61501.1 - 3e-09 36.7 0.0 5.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR61501.1 - 2.2e-06 27.9 0.0 4.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 EMR61501.1 - 3.7e-05 23.7 0.0 0.00038 20.4 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding AMP-binding_C PF13193.6 EMR61501.1 - 0.00053 20.9 0.0 0.0026 18.7 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EMR61501.1 - 0.0023 17.0 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMR61501.1 - 0.015 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMR61501.1 - 0.052 12.9 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF726 PF05277.12 EMR61502.1 - 6.1e-125 416.7 0.4 8.8e-125 416.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EMR61502.1 - 0.0023 18.1 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EMR61502.1 - 0.038 13.2 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PE-PPE PF08237.11 EMR61502.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Tubulin_C PF03953.17 EMR61502.1 - 0.081 13.1 0.4 0.19 11.9 0.4 1.5 1 0 0 1 1 1 0 Tubulin C-terminal domain CttA_N PF18244.1 EMR61502.1 - 0.17 12.3 1.7 0.2 12.1 0.1 1.9 2 0 0 2 2 2 0 Cellulose-binding protein CttA N-terminal domain Abhydrolase_6 PF12697.7 EMR61502.1 - 0.33 11.5 3.1 0.24 12.0 0.2 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family TMEM215 PF15746.5 EMR61502.1 - 1.4 8.3 3.5 0.44 10.0 0.1 1.8 2 0 0 2 2 2 0 TMEM215 family Tyrosinase PF00264.20 EMR61503.1 - 7.4e-51 173.6 0.1 1.2e-50 172.9 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EMR61503.1 - 1.5e-32 112.8 0.0 2.4e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain HEAT PF02985.22 EMR61504.1 - 3.3e-06 26.9 3.8 0.078 13.3 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EMR61504.1 - 0.011 15.8 0.0 0.22 11.6 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMR61504.1 - 0.049 14.0 4.9 1 9.8 0.1 4.9 5 2 0 5 5 5 0 HEAT repeats HK PF02110.15 EMR61505.1 - 4.9e-69 232.5 4.3 7e-69 231.9 4.3 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EMR61505.1 - 5.8e-56 188.7 0.2 1e-55 187.9 0.2 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase ADH_zinc_N PF00107.26 EMR61505.1 - 0.02 14.9 0.9 1.6 8.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Acetyltransf_3 PF13302.7 EMR61506.1 - 3.6e-15 56.9 0.0 6.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR61506.1 - 1.5e-07 31.7 0.0 2.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EMR61506.1 - 0.031 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Adhesin_P1_N PF18652.1 EMR61507.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain BP28CT PF08146.12 EMR61509.1 - 1.5e-45 154.8 0.2 5.9e-45 152.9 0.2 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EMR61509.1 - 2.8e-25 88.9 14.6 1.2e-24 86.9 0.0 6.1 6 1 1 8 8 8 2 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 EMR61509.1 - 4.1e-05 23.5 9.7 0.41 11.0 0.2 6.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EMR61509.1 - 0.0028 18.0 11.7 1.6 9.2 0.2 6.6 5 2 1 6 6 6 2 HEAT repeats ERK-JNK_inhib PF15002.6 EMR61509.1 - 0.082 12.6 0.7 0.4 10.3 0.2 2.1 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor HEAT_EZ PF13513.6 EMR61509.1 - 0.39 11.3 13.1 63 4.2 0.1 7.2 7 1 0 7 7 7 0 HEAT-like repeat V-ATPase_H_N PF03224.14 EMR61509.1 - 3.7 6.7 11.1 0.074 12.3 1.2 3.3 4 0 0 4 4 4 0 V-ATPase subunit H SMBP PF16785.5 EMR61510.1 - 0.0093 16.2 4.2 0.012 15.8 4.2 1.2 1 0 0 1 1 1 1 Small metal-binding protein DUF2274 PF10038.9 EMR61510.1 - 0.092 13.2 0.3 0.16 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) Helicase_C PF00271.31 EMR61511.1 - 4.5e-18 65.6 0.0 6.5e-15 55.4 0.0 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 EMR61511.1 - 1.9e-15 57.1 0.0 3.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EMR61511.1 - 2.3e-11 44.3 1.2 5.6e-11 43.0 1.2 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Arm PF00514.23 EMR61511.1 - 0.22 11.7 0.6 0.84 9.8 0.2 2.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat NOA36 PF06524.12 EMR61512.1 - 5.5 6.2 13.5 9 5.5 13.5 1.2 1 0 0 1 1 1 0 NOA36 protein Pyr_redox_2 PF07992.14 EMR61513.1 - 8.5e-62 209.0 1.5 1.3e-61 208.5 1.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMR61513.1 - 7.3e-32 109.9 0.1 2.1e-31 108.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMR61513.1 - 1.4e-17 64.0 0.8 5.5e-16 58.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR61513.1 - 7.9e-15 54.9 0.7 9.8e-15 54.6 0.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR61513.1 - 0.00031 19.6 3.0 2.3 6.8 1.4 3.1 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 EMR61513.1 - 0.00054 19.2 0.0 0.0012 18.0 0.0 1.6 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EMR61513.1 - 0.00064 19.2 0.1 0.0011 18.4 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR61513.1 - 0.01 15.1 0.6 0.019 14.2 0.6 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EMR61513.1 - 0.019 14.1 0.2 0.047 12.8 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EMR61513.1 - 0.024 14.9 1.7 0.057 13.6 1.7 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EMR61513.1 - 0.048 13.6 0.2 0.4 10.5 0.0 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EMR61513.1 - 0.087 11.9 0.1 0.23 10.5 0.1 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR61513.1 - 0.16 11.0 2.4 0.39 9.7 2.4 1.7 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EMR61513.1 - 0.26 10.9 2.3 0.31 10.6 1.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMR61513.1 - 0.27 10.5 1.7 8.6 5.6 0.6 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EMR61513.1 - 0.45 9.8 2.5 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LsmAD PF06741.13 EMR61514.1 - 2.9e-28 98.2 2.5 2.9e-28 98.2 2.5 2.8 2 0 0 2 2 2 1 LsmAD domain DUF677 PF05055.12 EMR61514.1 - 0.011 14.7 0.3 0.019 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3018 PF11455.8 EMR61514.1 - 1.6 8.7 4.1 2 8.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Ydc2-catalyt PF09159.10 EMR61515.1 - 5e-65 220.0 0.0 5.9e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EMR61515.1 - 0.0011 19.1 0.0 1.6 8.8 0.0 3.2 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.27 EMR61515.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 SAP domain Ribosomal_L22 PF00237.19 EMR61517.1 - 4.1e-20 71.9 0.0 8.8e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CFEM PF05730.11 EMR61518.1 - 1.2e-08 34.9 4.5 1.2e-08 34.9 4.5 1.3 1 1 0 1 1 1 1 CFEM domain TIL PF01826.17 EMR61518.1 - 2 8.7 8.5 0.51 10.6 5.3 1.6 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain 2OG-FeII_Oxy_2 PF13532.6 EMR61519.1 - 3.2e-26 92.8 0.0 4.7e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cwf_Cwc_15 PF04889.12 EMR61519.1 - 1.1 8.9 20.1 0.72 9.5 1.6 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GP67 PF17634.2 EMR61519.1 - 6.9 7.2 22.7 5.8 7.4 6.3 3.3 3 0 0 3 3 3 0 Gene product 67 STE2 PF02116.15 EMR61520.1 - 1e-50 172.7 2.0 1.4e-50 172.2 1.1 1.6 2 0 0 2 2 2 1 Fungal pheromone mating factor STE2 GPCR Isochorismatase PF00857.20 EMR61521.1 - 4.6e-26 92.1 0.0 1.5e-25 90.4 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family Pkinase_Tyr PF07714.17 EMR61522.1 - 2.3e-15 56.6 0.0 1.3e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.6 EMR61522.1 - 3e-12 46.1 9.0 2.9e-06 27.0 0.3 3.3 2 1 2 4 4 4 4 Leucine rich repeat Pkinase PF00069.25 EMR61522.1 - 1.8e-11 43.9 0.0 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 EMR61522.1 - 1.9e-07 31.3 1.8 0.021 15.3 0.0 3.8 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) Kdo PF06293.14 EMR61522.1 - 0.00031 20.2 4.8 0.00054 19.4 4.8 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMR61522.1 - 0.0068 15.7 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Kinase-like LRR_1 PF00560.33 EMR61522.1 - 0.0074 16.7 2.6 3 8.8 0.1 3.8 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_9 PF14580.6 EMR61522.1 - 0.14 11.7 0.0 0.39 10.2 0.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeat Bromo_TP PF07524.13 EMR61523.1 - 1.8e-15 56.7 0.0 1.2e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 EMR61523.1 - 1.1e-14 54.7 0.1 1.1e-14 54.7 0.1 2.3 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term GlutR_dimer PF00745.20 EMR61523.1 - 0.22 12.0 3.8 0.77 10.3 3.5 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain PNKP-ligase_C PF16536.5 EMR61523.1 - 2.8 8.3 6.2 1.6 9.0 1.6 2.4 1 1 1 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region WD40 PF00400.32 EMR61524.1 - 1.6e-44 149.0 25.1 1.1e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR61524.1 - 4.3e-09 36.5 0.7 0.058 13.7 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR61524.1 - 1.3e-05 24.1 5.6 0.064 11.9 0.1 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EMR61524.1 - 0.0031 16.9 0.0 0.47 9.7 0.0 2.7 2 1 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EMR61524.1 - 0.0035 16.4 0.0 9.8 5.0 0.0 3.9 1 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EMR61524.1 - 0.0091 15.9 0.6 22 5.1 0.0 4.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EMR61524.1 - 0.015 13.8 0.0 2.6 6.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain mRNA_stabil PF13929.6 EMR61524.1 - 0.18 10.7 0.1 0.58 9.1 0.0 1.7 2 0 0 2 2 2 0 mRNA stabilisation VID27 PF08553.10 EMR61524.1 - 0.21 10.6 0.0 0.6 9.1 0.0 1.7 2 1 0 2 2 2 0 VID27 C-terminal WD40-like domain Sugar_tr PF00083.24 EMR61525.1 - 3.8e-81 273.3 23.7 4.7e-81 273.0 23.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR61525.1 - 2.9e-17 62.6 29.1 8.6e-14 51.2 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR61525.1 - 2 7.2 23.0 0.04 12.8 9.7 2.2 2 0 0 2 2 2 0 MFS_1 like family Pro-kuma_activ PF09286.11 EMR61526.1 - 5.8e-40 136.9 0.0 2.6e-39 134.8 0.0 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMR61526.1 - 8.4e-05 22.0 1.1 0.00014 21.2 1.1 1.3 1 0 0 1 1 1 1 Subtilase family Disintegrin PF00200.23 EMR61527.1 - 8e-16 58.6 36.2 8e-16 58.6 36.2 4.1 4 1 0 4 4 4 1 Disintegrin ADAM_CR_2 PF17771.1 EMR61527.1 - 0.00012 22.6 13.0 0.00012 22.6 13.0 4.5 1 1 3 4 4 4 1 ADAM cysteine-rich domain Reprolysin_2 PF13574.6 EMR61527.1 - 0.0094 15.9 0.1 0.0094 15.9 0.1 2.8 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like GRP PF07172.11 EMR61527.1 - 9.8 6.9 16.5 0.67 10.7 10.7 2.1 2 0 0 2 2 2 0 Glycine rich protein family Glyco_hydro_16 PF00722.21 EMR61529.1 - 7.4e-42 142.8 1.3 1.2e-41 142.1 1.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.22 EMR61530.1 - 2.4e-58 198.0 0.0 2.1e-57 194.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 MMR_HSR1 PF01926.23 EMR61531.1 - 1.6e-07 31.4 0.2 3.1e-06 27.2 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EMR61531.1 - 1.9e-05 24.1 0.0 0.17 11.2 0.0 3.2 3 0 0 3 3 3 2 AIG1 family RsgA_GTPase PF03193.16 EMR61531.1 - 2.1e-05 24.5 0.4 9.8e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EMR61531.1 - 0.001 19.6 0.1 0.0043 17.6 0.1 2.1 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 EMR61531.1 - 0.0011 19.1 1.6 0.66 10.0 0.0 3.0 3 0 0 3 3 3 2 Dynamin family AAA_29 PF13555.6 EMR61531.1 - 0.0017 18.1 0.1 0.004 16.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 EMR61531.1 - 0.0024 17.2 0.1 0.011 15.0 0.1 2.1 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 EMR61531.1 - 0.0025 18.2 0.0 0.0067 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR61531.1 - 0.0058 16.9 0.0 0.96 9.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EMR61531.1 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family GTP_EFTU PF00009.27 EMR61531.1 - 0.0066 16.0 0.2 0.018 14.6 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EMR61531.1 - 0.0089 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EMR61531.1 - 0.009 16.5 0.2 0.078 13.5 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 EMR61531.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EMR61531.1 - 0.034 13.9 0.0 0.091 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EMR61531.1 - 0.039 13.0 0.0 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Roc PF08477.13 EMR61531.1 - 0.049 13.9 0.0 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EMR61531.1 - 0.059 13.8 0.1 0.27 11.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 EMR61531.1 - 0.064 13.3 0.4 0.33 11.0 0.0 2.4 3 0 0 3 3 3 0 Helicase HerA, central domain Spore_IV_A PF09547.10 EMR61531.1 - 0.064 12.2 0.0 0.15 11.0 0.0 1.6 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_7 PF12775.7 EMR61531.1 - 0.1 12.1 0.0 0.36 10.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP-synt PF00231.19 EMR61532.1 - 3e-81 273.2 4.2 3.7e-81 272.9 4.2 1.0 1 0 0 1 1 1 1 ATP synthase Thg1C PF14413.6 EMR61532.1 - 0.15 12.2 1.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Thg1 C terminal domain ORC6 PF05460.13 EMR61533.1 - 0.07 12.4 0.2 0.12 11.6 0.2 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FXMRP1_C_core PF12235.8 EMR61533.1 - 2 9.1 6.8 0.99 10.0 4.6 1.6 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal WcbI PF18588.1 EMR61534.1 - 0.028 14.0 0.2 0.054 13.1 0.2 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI DEPP PF15343.6 EMR61534.1 - 0.095 12.8 7.3 0.19 11.8 7.3 1.6 1 0 0 1 1 1 0 Decidual protein induced by progesterone family CorA PF01544.18 EMR61535.1 - 1.5e-12 47.4 2.2 1.7e-12 47.3 2.2 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sec1 PF00995.23 EMR61539.1 - 5.1e-63 214.2 0.0 6.3e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family VGLL4 PF15245.6 EMR61539.1 - 0.16 12.0 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 ABM PF03992.16 EMR61540.1 - 2.4e-11 43.6 0.0 1.5e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AAA_2 PF07724.14 EMR61542.1 - 5.4e-13 49.4 0.0 1.6e-12 47.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EMR61542.1 - 1.2e-11 44.8 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMR61542.1 - 7e-07 29.7 0.0 1.4e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EMR61542.1 - 0.0002 20.8 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ClpB_D2-small PF10431.9 EMR61542.1 - 0.0011 18.9 0.1 0.0032 17.5 0.1 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 EMR61542.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_6 PF12774.7 EMR61542.1 - 0.05 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 EMR61542.1 - 0.071 13.3 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMR61542.1 - 0.1 13.0 0.4 13 6.1 0.0 2.8 2 2 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EMR61542.1 - 0.13 12.6 0.1 0.68 10.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain Topoisom_I PF01028.20 EMR61543.1 - 2.1e-97 324.9 8.7 6.9e-97 323.2 8.7 1.9 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EMR61543.1 - 3.2e-95 317.7 3.6 3.2e-95 317.7 3.6 2.8 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EMR61543.1 - 4.4e-32 109.8 0.5 1.4e-31 108.3 0.5 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain Aminotran_1_2 PF00155.21 EMR61544.1 - 4.4e-14 52.4 0.0 7.5e-14 51.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EMR61544.1 - 0.00028 19.8 0.0 0.0015 17.4 0.0 1.9 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 EMR61544.1 - 0.23 10.7 0.0 0.56 9.5 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family NmrA PF05368.13 EMR61545.1 - 7.5e-37 127.1 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR61545.1 - 4.6e-19 69.0 0.0 9.8e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR61545.1 - 0.014 14.8 0.0 0.065 12.7 0.1 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Amino_oxidase PF01593.24 EMR61546.1 - 8.2e-71 239.6 0.0 1.2e-70 239.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HMG_box PF00505.19 EMR61546.1 - 8.7e-07 29.3 2.2 1.6e-06 28.4 1.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR61546.1 - 6e-06 26.8 1.7 1.3e-05 25.7 1.7 1.5 1 0 0 1 1 1 1 HMG-box domain tRNA-synt_His PF13393.6 EMR61547.1 - 7.8e-40 137.1 0.0 1.9e-33 116.1 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EMR61547.1 - 1.1e-12 47.9 0.0 2.7e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EMR61547.1 - 5.3e-05 23.3 0.0 0.00023 21.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EMR61547.1 - 0.008 15.3 0.0 0.077 12.1 0.0 2.0 1 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 EMR61547.1 - 0.0093 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Taxilin PF09728.9 EMR61548.1 - 0.014 14.6 24.3 0.024 13.9 24.3 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein BRE1 PF08647.11 EMR61548.1 - 0.024 14.7 2.0 0.024 14.7 2.0 3.1 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Spectrin PF00435.21 EMR61548.1 - 0.12 12.9 18.7 0.8 10.2 2.7 2.7 2 1 1 3 3 3 0 Spectrin repeat HalX PF08663.10 EMR61548.1 - 0.51 10.7 11.4 0.3 11.4 3.3 3.6 2 2 2 4 4 4 0 HalX domain Syntaxin-6_N PF09177.11 EMR61548.1 - 1.4 9.5 12.7 1.3 9.6 5.4 2.7 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Goodbye PF17109.5 EMR61548.1 - 2 8.8 7.4 0.44 11.0 0.5 2.8 1 1 3 4 4 4 0 fungal STAND N-terminal Goodbye domain zf-C4H2 PF10146.9 EMR61548.1 - 7.2 6.9 20.5 9.6 6.4 6.4 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein HAUS-augmin3 PF14932.6 EMR61548.1 - 7.4 6.1 20.6 1.7 8.1 8.9 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Pkinase PF00069.25 EMR61549.1 - 1.5e-69 234.3 0.0 2.2e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR61549.1 - 5.3e-35 121.0 0.1 8.9e-35 120.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR61549.1 - 4.6e-06 26.2 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMR61549.1 - 0.00039 19.9 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMR61549.1 - 0.00087 18.2 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EMR61549.1 - 0.015 14.9 0.1 0.14 11.7 0.1 2.4 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL TetR_C_27 PF17935.1 EMR61549.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain UQ_con PF00179.26 EMR61550.1 - 1.1e-33 115.8 0.0 2.2e-21 76.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme HalX PF08663.10 EMR61550.1 - 0.049 13.9 0.5 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 HalX domain DUF2417 PF10329.9 EMR61551.1 - 6.2e-89 297.5 2.9 7.9e-89 297.1 2.9 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) ABC2_membrane_3 PF12698.7 EMR61551.1 - 0.45 9.6 11.0 0.66 9.0 11.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2070 PF09843.9 EMR61551.1 - 8.7 4.5 11.9 13 4.0 11.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_L29 PF00831.23 EMR61552.1 - 3.7e-15 55.6 1.9 3.7e-15 55.6 1.9 2.4 2 1 1 3 3 3 1 Ribosomal L29 protein Tctex-1 PF03645.13 EMR61552.1 - 0.11 12.7 0.2 2.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Tctex-1 family TBD PF12845.7 EMR61552.1 - 0.51 10.3 0.1 0.51 10.3 0.1 2.8 3 1 1 4 4 4 0 TBD domain 3Beta_HSD PF01073.19 EMR61553.1 - 4.2e-64 216.3 0.0 5.4e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMR61553.1 - 2e-31 109.3 0.5 3.3e-31 108.6 0.5 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR61553.1 - 1.5e-16 60.8 0.0 7.2e-16 58.5 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMR61553.1 - 1.7e-13 50.3 0.9 2.3e-13 49.9 0.9 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMR61553.1 - 8.1e-13 48.7 0.3 1.1e-12 48.2 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMR61553.1 - 1.7e-11 43.8 1.6 7.4e-09 35.1 0.3 2.2 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 EMR61553.1 - 7.7e-07 28.9 0.2 1.2e-06 28.3 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMR61553.1 - 8.2e-06 25.2 0.1 2.9e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 EMR61553.1 - 2e-05 24.8 0.9 4.9e-05 23.6 0.1 2.1 2 1 0 2 2 1 1 TrkA-N domain KR PF08659.10 EMR61553.1 - 0.0015 18.5 2.2 0.017 15.0 2.2 2.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EMR61553.1 - 0.006 16.8 0.7 0.071 13.4 0.7 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ATP-synt_10 PF05176.14 EMR61555.1 - 8e-61 205.5 0.0 9.5e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein TetR_C_28 PF17937.1 EMR61555.1 - 0.054 13.9 0.2 0.11 13.0 0.2 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PPR_2 PF13041.6 EMR61556.1 - 6.8e-08 32.6 0.2 0.12 12.6 0.0 4.2 4 0 0 4 4 4 3 PPR repeat family PPR_3 PF13812.6 EMR61556.1 - 0.0014 18.7 0.0 0.23 11.5 0.0 3.7 4 1 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.20 EMR61556.1 - 0.0026 17.9 0.2 30 5.2 0.0 4.4 4 0 0 4 4 4 2 PPR repeat V-SNARE_C PF12352.8 EMR61557.1 - 1.5e-13 50.8 0.2 1.5e-13 50.8 0.2 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Not3 PF04065.15 EMR61557.1 - 0.067 12.6 1.2 0.46 9.9 0.3 2.2 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component LptF_LptG PF03739.14 EMR61557.1 - 0.086 11.7 0.0 0.099 11.5 0.0 1.3 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG FTA4 PF13093.6 EMR61557.1 - 0.14 12.1 6.9 3.5 7.5 5.3 2.8 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spc7 PF08317.11 EMR61557.1 - 0.25 10.2 5.5 0.18 10.7 3.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein UPF0184 PF03670.13 EMR61557.1 - 0.39 11.1 2.7 3.9 7.9 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) RhoGAP PF00620.27 EMR61558.1 - 2.7e-07 30.6 0.1 0.0012 18.7 0.0 2.4 1 1 1 2 2 2 2 RhoGAP domain Sec66 PF09802.9 EMR61559.1 - 2.7e-82 274.7 0.5 3.2e-82 274.5 0.5 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Rep_fac_C PF08542.11 EMR61560.1 - 5.7e-20 71.5 0.1 1.1e-19 70.6 0.1 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EMR61560.1 - 4.2e-16 59.6 0.0 2.4e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EMR61560.1 - 9.7e-13 48.2 0.2 4.6e-10 39.5 0.0 2.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EMR61560.1 - 1.1e-09 38.5 0.1 2.7e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EMR61560.1 - 3.8e-06 26.7 0.0 1.3e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMR61560.1 - 4e-06 27.3 0.4 0.0004 20.8 0.4 3.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 EMR61560.1 - 3.9e-05 23.6 0.0 8.1e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EMR61560.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EMR61560.1 - 0.00013 22.2 0.0 0.013 15.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EMR61560.1 - 0.00016 21.9 0.1 0.00058 20.1 0.1 2.0 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 EMR61560.1 - 0.00025 20.5 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EMR61560.1 - 0.0026 18.1 0.0 0.016 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EMR61560.1 - 0.0031 16.7 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EMR61560.1 - 0.0031 17.6 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMR61560.1 - 0.0031 17.2 0.1 0.014 15.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EMR61560.1 - 0.0045 16.5 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EMR61560.1 - 0.0057 16.6 0.9 0.14 12.1 0.1 3.1 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EMR61560.1 - 0.015 15.0 0.1 0.12 12.1 0.0 2.4 2 2 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMR61560.1 - 0.021 15.1 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMR61560.1 - 0.041 14.4 0.0 0.1 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EMR61560.1 - 0.044 13.8 0.0 0.16 12.0 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EMR61560.1 - 0.059 13.1 0.1 0.87 9.3 0.0 2.6 1 1 1 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 EMR61560.1 - 0.065 12.5 0.0 0.21 10.8 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 EMR61560.1 - 0.097 12.5 0.0 0.58 10.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMR61560.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF4863 PF16155.5 EMR61560.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) HMG_box_2 PF09011.10 EMR61561.1 - 4.3e-08 33.6 0.1 4.3e-08 33.6 0.1 3.0 3 0 0 3 3 3 1 HMG-box domain HMG_box PF00505.19 EMR61561.1 - 5e-06 26.8 4.7 1.2e-05 25.7 2.0 2.9 2 1 0 2 2 2 1 HMG (high mobility group) box Trypan_glycop PF00913.19 EMR61561.1 - 1.4e-05 24.6 12.3 3e-05 23.5 12.3 1.5 1 0 0 1 1 1 1 Trypanosome variant surface glycoprotein (A-type) Imm58 PF15581.6 EMR61561.1 - 0.0024 17.9 0.2 3.6 7.7 0.0 2.5 2 0 0 2 2 2 2 Immunity protein 58 TFIIA PF03153.13 EMR61562.1 - 0.00053 20.1 9.6 0.00053 20.1 9.6 2.2 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 EMR61562.1 - 0.11 11.9 17.0 0.19 11.1 17.0 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EMR61562.1 - 0.36 9.0 17.3 0.55 8.4 17.3 1.2 1 0 0 1 1 1 0 Nop14-like family PRCC PF10253.9 EMR61562.1 - 0.4 11.4 31.2 1.9 9.3 11.6 2.4 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting YL1 PF05764.13 EMR61562.1 - 0.7 10.0 26.1 0.24 11.5 21.5 2.0 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 EMR61562.1 - 0.85 7.8 20.0 1.3 7.2 20.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Spt20 PF12090.8 EMR61562.1 - 0.95 9.0 40.9 0.79 9.3 20.6 2.3 2 0 0 2 2 2 0 Spt20 family Lin-8 PF03353.15 EMR61562.1 - 1.6 8.2 23.1 0.12 11.9 10.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist NST1 PF13945.6 EMR61562.1 - 3.3 7.8 22.4 0.16 12.1 12.1 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator CCSAP PF15748.5 EMR61562.1 - 8.4 6.5 29.5 5.9 7.0 22.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Apt1 PF10351.9 EMR61562.1 - 8.5 5.1 15.8 2.1 7.1 12.4 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain Glyco_hydro_38N PF01074.22 EMR61563.1 - 2.1e-88 296.4 1.6 3.4e-88 295.7 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EMR61563.1 - 2.9e-55 187.6 0.3 2.6e-54 184.5 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EMR61563.1 - 1.9e-25 88.8 0.0 4.1e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EMR61563.1 - 6.6e-11 42.2 0.0 1.9e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain TubC_N PF18563.1 EMR61563.1 - 0.013 15.5 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 TubC N-terminal docking domain DEAD PF00270.29 EMR61564.1 - 3.8e-51 173.3 0.0 6.4e-50 169.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR61564.1 - 3.4e-27 95.0 0.0 1.2e-26 93.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR61564.1 - 0.0015 18.6 0.0 0.0053 16.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MutS_III PF05192.18 EMR61565.1 - 1.7e-40 139.3 1.6 2.6e-40 138.7 1.6 1.2 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EMR61565.1 - 2.5e-18 66.4 0.0 4.5e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EMR61565.1 - 1.8e-09 38.0 0.0 6.9e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 MutS domain II DUF3499 PF12005.8 EMR61565.1 - 0.84 10.2 3.3 24 5.5 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) RTC_insert PF05189.13 EMR61567.1 - 1.3e-29 102.7 0.9 2e-29 102.2 0.2 1.7 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EMR61567.1 - 6.8e-27 94.1 0.3 8.4e-27 93.8 0.3 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Mem_trans PF03547.18 EMR61568.1 - 2e-23 82.4 0.1 2.9e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 Membrane transport protein Spt20 PF12090.8 EMR61568.1 - 0.063 12.9 10.1 0.089 12.4 10.1 1.1 1 0 0 1 1 1 0 Spt20 family PWWP PF00855.17 EMR61570.1 - 3.5e-12 46.6 0.0 3.5e-12 46.6 0.0 3.1 3 0 0 3 3 3 1 PWWP domain Pkinase_fungal PF17667.1 EMR61570.1 - 2.7 6.6 6.0 7.3 5.2 6.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase CPSase_L_D2 PF02786.17 EMR61571.1 - 7.2e-110 365.5 0.0 3.1e-84 281.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EMR61571.1 - 2e-39 134.7 0.0 5.6e-39 133.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EMR61571.1 - 4.2e-19 68.8 0.0 1e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EMR61571.1 - 1e-17 64.4 0.4 5.6e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EMR61571.1 - 3.8e-11 42.9 0.0 0.00038 20.2 0.0 3.0 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 EMR61571.1 - 6.8e-05 22.7 1.7 0.091 12.5 0.1 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 EMR61571.1 - 0.00016 21.2 0.1 0.54 9.7 0.1 2.8 2 1 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EMR61571.1 - 0.0028 17.3 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain NPL4 PF05021.15 EMR61574.1 - 1.9e-137 457.7 0.0 2.5e-137 457.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EMR61574.1 - 1.2e-66 223.3 0.1 2e-66 222.6 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EMR61574.1 - 3.6e-05 24.2 0.0 6.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec63 PF02889.16 EMR61575.1 - 5.1e-165 546.9 0.6 6.8e-92 307.3 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EMR61575.1 - 2.4e-49 167.5 0.1 2.2e-28 99.2 0.1 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EMR61575.1 - 9.8e-35 119.1 0.2 3.5e-34 117.3 0.2 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EMR61575.1 - 1.5e-25 90.2 0.0 4.7e-15 56.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMR61575.1 - 1.9e-12 47.5 0.0 8e-08 32.6 0.0 3.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EMR61575.1 - 7e-07 29.6 0.1 0.021 15.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EMR61575.1 - 0.0025 17.3 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EMR61575.1 - 0.0056 15.8 0.0 1.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein TFIIE_alpha PF02002.17 EMR61575.1 - 0.041 13.7 1.0 15 5.5 0.1 3.3 3 0 0 3 3 3 0 TFIIE alpha subunit HET PF06985.11 EMR61576.1 - 1.1e-11 45.3 6.7 2e-10 41.2 1.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TLD PF07534.16 EMR61577.1 - 4.6e-25 88.5 0.0 1.9e-24 86.5 0.0 2.0 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 EMR61577.1 - 7.8e-15 55.7 0.3 1.8e-14 54.5 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function Rhodanese PF00581.20 EMR61578.1 - 4.4e-22 78.6 0.0 1.5e-12 47.9 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Ribosomal_S5 PF00333.20 EMR61579.1 - 1.6e-26 92.0 1.0 3.3e-26 91.0 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EMR61579.1 - 3.6e-21 74.4 0.0 1.2e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain WSC PF01822.19 EMR61579.1 - 9.5e-10 38.5 0.6 1.7e-09 37.7 0.6 1.4 1 0 0 1 1 1 1 WSC domain Baculo_PEP_C PF04513.12 EMR61579.1 - 1.9 8.5 6.7 1.7 8.7 1.3 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIG_1_N PF04588.13 EMR61581.1 - 2.9e-22 78.6 1.0 2.9e-22 78.6 1.0 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Isy1 PF06246.12 EMR61581.1 - 0.0035 16.9 2.4 0.0047 16.5 2.4 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Tannase PF07519.11 EMR61582.1 - 2.2e-92 310.4 0.0 3e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Pec_lyase_C PF00544.19 EMR61583.1 - 3.6e-18 65.9 5.4 2.4e-16 60.0 5.4 2.4 1 1 0 1 1 1 1 Pectate lyase Acetyltransf_1 PF00583.25 EMR61584.1 - 1.1e-12 48.2 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR61584.1 - 4.7e-08 33.0 0.0 6.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR61584.1 - 5.2e-08 33.2 0.0 8.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR61584.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EMR61584.1 - 0.012 16.3 0.0 0.017 15.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMR61584.1 - 0.065 13.4 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.11 EMR61585.1 - 2.5e-31 109.0 0.3 5.8e-31 107.8 0.3 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BUD22 PF09073.10 EMR61585.1 - 0.0071 15.7 4.4 0.011 15.1 4.4 1.3 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 EMR61585.1 - 0.073 12.5 12.8 0.14 11.6 12.8 1.3 1 0 0 1 1 1 0 SDA1 BSP_II PF05432.11 EMR61585.1 - 0.49 10.0 13.0 0.82 9.3 13.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.12 EMR61585.1 - 2.3 7.4 23.5 0.12 11.7 16.7 2.0 2 0 0 2 2 2 0 NOA36 protein TFB6 PF17110.5 EMR61585.1 - 2.4 7.9 7.2 5.4 6.7 6.4 1.9 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH CobT PF06213.12 EMR61585.1 - 2.8 7.3 17.7 4.9 6.5 17.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 EMR61585.1 - 6.6 4.9 14.4 11 4.1 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EMR61585.1 - 7.2 4.7 20.8 11 4.1 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 EMR61585.1 - 9.3 5.1 10.0 14 4.5 10.0 1.2 1 0 0 1 1 1 0 Paf1 Radial_spoke PF04712.12 EMR61585.1 - 9.8 5.0 8.1 16 4.3 8.1 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein ADH_N PF08240.12 EMR61586.1 - 8.1e-10 38.6 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR61586.1 - 7.8e-06 25.9 0.3 1.7e-05 24.8 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR61586.1 - 0.066 12.7 0.6 0.14 11.6 0.2 1.8 2 0 0 2 2 2 0 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EMR61586.1 - 0.067 14.2 0.1 0.21 12.6 0.0 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Fungal_lectin PF07938.12 EMR61587.1 - 6e-08 32.4 0.1 1.5e-05 24.6 0.0 3.0 2 1 0 2 2 2 1 Fungal fucose-specific lectin AAR2 PF05282.11 EMR61587.1 - 0.015 14.7 0.5 0.019 14.4 0.5 1.2 1 0 0 1 1 1 0 AAR2 protein Radial_spoke_3 PF06098.11 EMR61587.1 - 0.6 9.3 14.0 0.8 8.9 14.0 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 DUF1764 PF08576.10 EMR61587.1 - 1.2 10.1 9.2 2.3 9.2 9.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CDC45 PF02724.14 EMR61587.1 - 1.4 7.1 7.4 1.9 6.7 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EMR61587.1 - 2.1 8.1 7.9 3.3 7.5 7.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EMR61587.1 - 2.4 6.8 4.2 3.3 6.4 4.2 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EMR61587.1 - 3.9 7.2 4.9 6.1 6.5 4.9 1.2 1 0 0 1 1 1 0 Connexin PALP PF00291.25 EMR61588.1 - 1.5e-75 254.4 0.3 1.9e-75 254.0 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EMR61588.1 - 1.5e-36 124.1 0.0 1.9e-19 69.2 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Epimerase PF01370.21 EMR61589.1 - 1.6e-17 63.8 0.0 2.3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR61589.1 - 5.6e-12 45.2 0.0 1.1e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMR61589.1 - 1.5e-10 40.7 0.0 4.4e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EMR61589.1 - 1.4e-09 38.1 0.0 7.1e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR61589.1 - 3.6e-09 36.5 0.2 3e-08 33.5 0.1 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMR61589.1 - 1.9e-06 27.6 0.1 0.0024 17.5 0.1 2.9 2 1 0 2 2 2 2 NmrA-like family KR PF08659.10 EMR61589.1 - 6.7e-05 22.9 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR61589.1 - 0.00036 19.8 0.0 0.00084 18.5 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EMR61589.1 - 0.0014 18.2 0.1 0.0034 16.9 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 EMR61589.1 - 0.0016 19.0 0.0 0.0099 16.4 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EMR61589.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Bac_luciferase PF00296.20 EMR61590.1 - 7.4e-23 81.5 0.0 8.8e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 EMR61590.1 - 0.096 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase DUF4029 PF13221.6 EMR61591.1 - 3 8.6 10.6 1 10.1 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4029) Ac110_PIF PF07280.11 EMR61591.1 - 5.6 6.8 9.9 4.7 7.1 0.4 3.4 3 0 0 3 3 3 0 Per os infectivity factor AC110 EHN PF06441.12 EMR61592.1 - 4.4e-29 101.0 0.1 8.9e-29 100.0 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMR61592.1 - 1.7e-10 41.0 0.3 2.8e-10 40.3 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 EMR61593.1 - 1.7e-32 112.7 29.3 2.3e-32 112.3 29.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF892 PF05974.12 EMR61594.1 - 0.037 14.0 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Mcm10 PF09332.11 EMR61594.1 - 0.14 11.5 0.2 0.21 10.9 0.2 1.2 1 0 0 1 1 1 0 Mcm10 replication factor TPR_19 PF14559.6 EMR61595.1 - 9.1e-05 22.9 0.5 0.55 10.8 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat FMO-like PF00743.19 EMR61596.1 - 4.8e-05 22.0 0.0 0.0018 16.8 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR61596.1 - 6.9e-05 22.3 0.0 0.00043 19.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR61596.1 - 0.00027 20.2 0.1 0.0019 17.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMR61596.1 - 0.19 11.0 0.4 10 5.2 0.0 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 EMR61597.1 - 1.4e-09 38.9 0.2 1.7e-09 38.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR61597.1 - 0.00069 18.9 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR61597.1 - 0.027 14.1 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold LtrA PF06772.11 EMR61599.1 - 5.1e-11 42.4 19.4 7.3e-10 38.6 14.8 2.8 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Phage_holin_3_6 PF07332.11 EMR61599.1 - 1.6 8.8 5.6 3.5 7.7 0.1 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III MnhB PF04039.13 EMR61599.1 - 2 8.7 10.3 4.3 7.7 0.6 3.4 3 0 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter adh_short_C2 PF13561.6 EMR61600.1 - 2.4e-53 181.1 7.2 9.8e-53 179.1 7.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR61600.1 - 4.1e-40 137.3 4.7 1e-39 136.0 4.7 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR61600.1 - 2.1e-09 37.5 3.9 1.4e-07 31.6 0.4 2.7 3 0 0 3 3 3 2 KR domain Polysacc_synt_2 PF02719.15 EMR61600.1 - 0.0062 15.7 0.2 0.0099 15.0 0.2 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMR61600.1 - 0.11 11.9 0.1 0.24 10.8 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 EMR61600.1 - 0.45 10.6 2.9 0.43 10.7 0.2 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.26 EMR61601.1 - 1.5e-34 119.2 0.0 1.8e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMR61601.1 - 6.9e-12 45.7 0.0 8.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EMR61601.1 - 2e-05 24.2 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMR61601.1 - 6.5e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Amidoligase_2 PF12224.8 EMR61602.1 - 4.4e-10 39.6 0.0 5.7e-07 29.5 0.0 2.6 3 0 0 3 3 3 2 Putative amidoligase enzyme ADH_N PF08240.12 EMR61603.1 - 1.8e-16 60.0 0.1 4.6e-16 58.7 0.1 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR61603.1 - 3.3e-09 36.8 0.3 3.3e-08 33.6 0.3 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR61603.1 - 0.00025 20.6 0.0 0.00057 19.4 0.0 1.7 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EMR61603.1 - 0.033 13.5 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EMR61603.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EMR61603.1 - 0.19 10.4 0.1 0.37 9.4 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Abhydrolase_3 PF07859.13 EMR61604.1 - 4e-42 144.5 0.1 5e-42 144.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR61604.1 - 0.0049 16.4 0.0 0.37 10.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EMR61604.1 - 0.018 14.6 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family COesterase PF00135.28 EMR61604.1 - 0.035 13.0 0.3 0.078 11.8 0.3 1.5 1 1 0 1 1 1 0 Carboxylesterase family Eno-Rase_NADH_b PF12242.8 EMR61604.1 - 0.071 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FSH1 PF03959.13 EMR61604.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_M18 PF02127.15 EMR61605.1 - 1e-168 561.6 0.0 5.9e-168 559.1 0.0 1.8 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EMR61605.1 - 4.7e-06 25.8 0.2 0.00027 20.1 0.0 2.8 2 1 0 3 3 3 1 M42 glutamyl aminopeptidase Xpo1 PF08389.12 EMR61606.1 - 4.2e-32 111.3 0.3 7.1e-31 107.3 0.0 3.1 3 1 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 EMR61606.1 - 0.02 15.1 0.0 18 6.0 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat DUF4844 PF16133.5 EMR61606.1 - 0.086 13.4 0.2 6.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) NTF2 PF02136.20 EMR61608.1 - 4.5e-24 85.3 0.9 7.6e-24 84.6 0.9 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EMR61608.1 - 3.2e-06 26.9 0.1 5.6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EMR61608.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif Sushi_2 PF09014.10 EMR61608.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain Glyco_hydro_10 PF00331.20 EMR61609.1 - 1.2e-96 323.6 0.0 1.5e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 EMR61609.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase SprA-related PF12118.8 EMR61609.1 - 0.94 8.6 12.0 1.4 8.0 12.0 1.3 1 0 0 1 1 1 0 SprA-related family Pneumo_att_G PF05539.11 EMR61609.1 - 1.5 8.4 17.7 2 7.9 17.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Mucin PF01456.17 EMR61609.1 - 1.6 8.7 34.5 3.7 7.6 34.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Alpha_GJ PF03229.13 EMR61609.1 - 4.6 7.8 19.8 15 6.1 19.8 2.0 1 0 0 1 1 1 0 Alphavirus glycoprotein J Nipped-B_C PF12830.7 EMR61610.1 - 3e-48 164.3 1.3 2.1e-47 161.5 0.4 2.7 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EMR61610.1 - 3.7e-09 36.7 3.1 4.6e-07 30.0 0.2 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EMR61610.1 - 1.9e-05 24.5 0.1 0.037 14.3 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EMR61610.1 - 0.0002 21.4 0.5 0.0053 16.8 0.2 2.8 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EMR61610.1 - 0.00073 18.2 3.7 0.0013 17.4 0.2 3.0 3 0 0 3 3 3 1 Adaptin N terminal region CDC45 PF02724.14 EMR61610.1 - 1.2 7.3 4.8 2.1 6.6 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein HEAT_2 PF13646.6 EMR61611.1 - 1.5e-24 86.2 6.5 5.8e-11 42.6 0.0 3.6 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 EMR61611.1 - 2.5e-17 61.7 7.7 0.033 14.9 0.0 6.7 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EMR61611.1 - 3.1e-06 27.0 3.5 2 8.9 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EMR61611.1 - 0.0067 16.9 7.2 2.2 8.9 0.1 5.0 3 2 2 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 EMR61611.1 - 0.042 13.9 0.2 6.8 6.7 0.0 3.5 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3632 PF12311.8 EMR61612.1 - 1.1e-28 100.9 0.0 1.4e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) PNP_phzG_C PF10590.9 EMR61613.1 - 1.4e-20 73.0 0.2 1.4e-20 73.0 0.2 2.5 3 1 1 4 4 4 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EMR61613.1 - 3.8e-19 68.7 0.0 6.3e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EMR61613.1 - 0.019 15.5 0.0 0.055 14.1 0.0 1.8 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Collagen PF01391.18 EMR61614.1 - 0.0011 18.6 12.0 0.0011 18.6 12.0 2.0 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) TFIIS_C PF01096.18 EMR61616.1 - 2.3e-14 53.0 1.6 2.3e-14 53.0 1.6 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EMR61616.1 - 9.5e-06 25.4 4.0 9.5e-06 25.4 4.0 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit UCH_1 PF13423.6 EMR61616.1 - 0.023 14.3 1.2 0.028 14.0 1.2 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase EPF PF17181.4 EMR61616.1 - 0.037 14.0 0.5 0.037 14.0 0.5 1.9 3 0 0 3 3 3 0 Epidermal patterning factor proteins Zot PF05707.12 EMR61616.1 - 0.069 12.8 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) zinc_ribbon_2 PF13240.6 EMR61616.1 - 0.083 12.6 16.3 3.1 7.6 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_7 PF02591.15 EMR61616.1 - 0.49 10.6 7.4 33 4.8 0.1 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain Ribosomal_L37ae PF01780.19 EMR61616.1 - 0.52 10.4 4.2 0.68 10.1 0.2 2.3 2 1 0 2 2 2 0 Ribosomal L37ae protein family CpXC PF14353.6 EMR61616.1 - 4.2 7.4 7.4 2.7 8.0 0.6 2.7 2 1 1 3 3 3 0 CpXC protein CorA PF01544.18 EMR61618.1 - 2e-09 37.2 0.1 2.7e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 EMR61618.1 - 0.03 13.1 0.0 0.033 13.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3169 PF11368.8 EMR61618.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) SASA PF03629.18 EMR61618.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase DUF4570 PF15134.6 EMR61618.1 - 0.13 12.3 0.4 0.67 10.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) IBR PF01485.21 EMR61619.1 - 1.5e-05 25.1 5.6 1.5e-05 25.1 5.6 4.0 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain ATP19 PF11022.8 EMR61621.1 - 5.9e-31 106.6 0.1 6.9e-31 106.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Rieske PF00355.26 EMR61623.1 - 4.1e-11 42.7 0.0 7.7e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EMR61623.1 - 4.6e-09 36.6 1.5 3.9e-08 33.6 1.5 2.3 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region adh_short PF00106.25 EMR61624.1 - 3.2e-32 111.6 0.0 4.6e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR61624.1 - 3.9e-19 69.1 0.0 6.5e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR61624.1 - 9.9e-09 35.4 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR61624.1 - 7.2e-05 22.4 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MTP18 PF10558.9 EMR61626.1 - 6.9e-85 283.3 0.1 8.9e-85 282.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Miga PF10265.9 EMR61627.1 - 2.5 7.0 10.2 4.5 6.1 10.2 1.4 1 0 0 1 1 1 0 Mitoguardin Cpn60_TCP1 PF00118.24 EMR61629.1 - 1.3e-151 505.6 14.6 1.5e-151 505.4 14.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-MYND PF01753.18 EMR61630.1 - 8.1e-09 35.4 16.2 1.5e-08 34.6 16.2 1.4 1 0 0 1 1 1 1 MYND finger PBP1_TM PF14812.6 EMR61631.1 - 0.15 12.5 1.1 0.26 11.7 1.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAA_hydrolase PF01557.18 EMR61632.1 - 6.9e-56 189.3 0.0 1.2e-55 188.5 0.0 1.3 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family RhoGEF PF00621.20 EMR61633.1 - 1.3e-16 61.4 0.3 7.6e-08 32.8 0.0 2.5 1 1 1 2 2 2 2 RhoGEF domain DUF3507 PF12015.8 EMR61633.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Rab5-bind PF09311.11 EMR61633.1 - 0.021 14.2 4.7 0.024 14.1 3.0 1.9 1 1 0 1 1 1 0 Rabaptin-like protein CdvA PF18822.1 EMR61633.1 - 0.27 11.1 8.5 1.6 8.5 3.0 2.9 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Aldolase_II PF00596.21 EMR61634.1 - 2.4e-47 161.3 0.2 3.1e-47 160.9 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Acetyltransf_7 PF13508.7 EMR61635.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR61635.1 - 0.012 15.7 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RecX PF02631.16 EMR61635.1 - 0.063 13.7 1.1 0.12 12.9 0.6 1.6 1 1 0 1 1 1 0 RecX family NeA_P2 PF12312.8 EMR61635.1 - 0.22 11.0 2.7 0.76 9.2 1.1 2.1 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein CAP_N PF01213.19 EMR61635.1 - 0.48 9.9 10.3 9.8 5.6 0.1 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EMR61635.1 - 2.6 8.1 9.5 1.2 9.2 6.0 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 MMS1_N PF10433.9 EMR61636.1 - 1.2e-124 416.6 0.2 1.9e-124 416.0 0.2 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EMR61636.1 - 6.3e-64 216.3 0.0 1.8e-63 214.8 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region zf-AN1 PF01428.16 EMR61638.1 - 2.9e-23 81.8 23.9 3.4e-12 46.3 9.1 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EMR61638.1 - 0.0029 17.8 13.2 0.075 13.3 3.0 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EMR61638.1 - 0.012 16.0 14.9 0.36 11.2 6.3 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Rad4 PF03835.15 EMR61639.1 - 1.1e-35 122.5 0.3 1.1e-35 122.5 0.3 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EMR61639.1 - 2.5e-28 98.3 0.5 5e-28 97.3 0.5 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EMR61639.1 - 1.1e-19 70.0 0.6 2.6e-19 68.8 0.6 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EMR61639.1 - 1.5e-13 51.5 0.1 1.5e-13 51.5 0.1 5.4 5 1 0 5 5 5 1 Rad4 beta-hairpin domain 2 MatE PF01554.18 EMR61640.1 - 0.0073 16.0 0.4 0.011 15.3 0.4 1.3 1 0 0 1 1 1 1 MatE DnaJ PF00226.31 EMR61641.1 - 3.7e-13 49.4 1.2 2.3e-12 46.9 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain API5 PF05918.11 EMR61641.1 - 0.52 9.1 5.7 0.7 8.6 5.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Presenilin PF01080.17 EMR61641.1 - 2.5 6.7 3.3 3.3 6.4 3.3 1.3 1 0 0 1 1 1 0 Presenilin DUF202 PF02656.15 EMR61642.1 - 2.7e-17 62.9 4.3 7.7e-17 61.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LtrA PF06772.11 EMR61642.1 - 0.0072 15.6 2.6 0.0096 15.2 2.6 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) TctB PF07331.11 EMR61642.1 - 0.06 13.6 2.9 0.081 13.2 2.9 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Calcyon PF06387.11 EMR61642.1 - 0.078 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) GWT1 PF06423.12 EMR61642.1 - 0.17 12.0 1.2 0.57 10.3 0.1 1.9 1 1 1 2 2 2 0 GWT1 Saf_2TM PF18303.1 EMR61642.1 - 0.32 10.6 3.7 9.9 5.7 1.0 2.1 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Tetraspanin PF00335.20 EMR61642.1 - 0.52 10.0 4.6 1.5 8.5 2.6 2.0 2 0 0 2 2 2 0 Tetraspanin family HEAT PF02985.22 EMR61644.1 - 0.13 12.6 0.1 1.5 9.3 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat RE_TaqI PF09573.10 EMR61644.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 TaqI restriction endonuclease Trypan_PARP PF05887.11 EMR61644.1 - 0.38 10.7 5.4 0.87 9.6 5.4 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.12 EMR61644.1 - 0.62 8.2 16.2 1.2 7.2 16.2 1.4 1 0 0 1 1 1 0 Nop14-like family SMBP PF16785.5 EMR61644.1 - 2.3 8.5 0.0 2.3 8.5 0.0 3.3 4 0 0 4 4 4 0 Small metal-binding protein BUD22 PF09073.10 EMR61644.1 - 3.8 6.8 14.0 2.4 7.4 11.8 1.7 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 EMR61644.1 - 7 6.0 21.5 0.23 10.8 15.2 1.6 2 0 0 2 2 2 0 SDA1 CNDH2_C PF16858.5 EMR61644.1 - 7.5 6.3 9.0 1.5 8.7 3.4 2.3 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DEAD PF00270.29 EMR61645.1 - 1e-48 165.4 0.0 6.4e-48 162.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR61645.1 - 2.4e-20 72.9 0.0 1.4e-18 67.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR61645.1 - 4.8e-08 33.2 0.0 9.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ccdc124 PF06244.12 EMR61646.1 - 4e-30 105.0 23.5 6.2e-29 101.2 23.5 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Mito_carr PF00153.27 EMR61647.1 - 1e-32 111.9 0.1 1.9e-20 72.6 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_14 PF01373.17 EMR61647.1 - 0.055 12.4 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Serine_protease PF18405.1 EMR61647.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Gammaproteobacterial serine protease RdRP_2 PF00978.21 EMR61648.1 - 3.2e-72 243.9 0.0 4.8e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Vmethyltransf PF01660.17 EMR61648.1 - 1.6e-38 132.5 0.4 2.5e-38 131.8 0.4 1.2 1 0 0 1 1 1 1 Viral methyltransferase Viral_helicase1 PF01443.18 EMR61648.1 - 8.1e-30 104.3 0.0 1.8e-29 103.2 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RdRP_4 PF02123.16 EMR61648.1 - 0.046 12.6 0.0 0.097 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase CBM46 PF18448.1 EMR61648.1 - 0.066 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain TFB6 PF17110.5 EMR61648.1 - 1 9.1 3.2 6.1 6.6 2.4 2.6 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF3325 PF11804.8 EMR61648.1 - 4.3 7.6 10.4 5.8 7.1 6.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) BrnA_antitoxin PF14384.6 EMR61649.1 - 0.13 12.8 0.1 0.31 11.5 0.1 1.6 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system OTT_1508_deam PF14441.6 EMR61650.1 - 1e-08 35.1 0.0 2.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-MYND PF01753.18 EMR61650.1 - 1.4e-05 25.1 9.6 4.7e-05 23.4 9.6 2.0 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EMR61650.1 - 0.001 19.1 3.1 0.004 17.2 3.1 2.1 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 EMR61650.1 - 0.028 14.7 6.7 0.17 12.2 6.7 2.3 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 EMR61650.1 - 0.21 11.5 12.0 0.034 14.0 7.6 2.0 2 0 0 2 2 2 0 HIT zinc finger DEAD PF00270.29 EMR61651.1 - 2.1e-12 47.2 0.0 9.7e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EMR61651.1 - 0.00015 21.8 2.2 0.00021 21.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMR61651.1 - 0.00044 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EMR61651.1 - 0.0031 16.6 0.1 0.01 14.9 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 EMR61651.1 - 0.028 14.8 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EMR61651.1 - 0.061 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_24 PF13578.6 EMR61651.1 - 0.11 13.5 0.0 0.35 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain SOBP PF15279.6 EMR61651.1 - 6.1 7.4 10.3 10 6.6 10.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Dynactin_p62 PF05502.13 EMR61652.1 - 1.6e-174 581.2 0.0 2.1e-174 580.8 0.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.18 EMR61653.1 - 1.3e-80 269.5 0.3 1.5e-80 269.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e MIF4G_like PF09088.11 EMR61657.1 - 3e-87 291.3 0.1 4.7e-87 290.7 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EMR61657.1 - 9.1e-73 245.0 0.0 1.5e-72 244.3 0.0 1.4 1 0 0 1 1 1 1 MIF4G like WD40 PF00400.32 EMR61657.1 - 3.5e-15 56.1 21.7 0.025 15.5 0.0 11.3 12 2 0 12 12 12 5 WD domain, G-beta repeat OMP_b-brl PF13505.6 EMR61657.1 - 0.027 14.6 2.6 0.077 13.1 2.6 1.7 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain DUF4410 PF14366.6 EMR61657.1 - 0.78 9.7 4.1 3.4 7.6 0.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) MscS_TM PF12794.7 EMR61657.1 - 1.1 8.0 6.5 0.048 12.5 0.6 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Fes1 PF08609.10 EMR61658.1 - 9.1e-31 106.6 5.8 5.1e-30 104.2 0.9 2.7 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 EMR61658.1 - 6.9e-05 22.8 0.5 0.11 12.8 0.1 3.6 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 EMR61658.1 - 0.0011 18.9 2.1 0.17 12.0 0.3 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EMR61658.1 - 0.012 16.0 2.3 9.3 6.7 0.0 3.3 2 1 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 EMR61658.1 - 0.017 15.6 0.4 7.8 7.1 0.1 2.9 2 0 0 2 2 2 0 HEAT-like repeat V-ATPase_H_N PF03224.14 EMR61658.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H V-ATPase_H_C PF11698.8 EMR61658.1 - 0.14 12.3 0.0 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 V-ATPase subunit H UCH_1 PF13423.6 EMR61659.1 - 8.9e-08 32.1 0.1 1.2e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_2 PF00891.18 EMR61660.1 - 1.2e-18 67.2 0.0 2.2e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain WSC PF01822.19 EMR61662.1 - 4.4e-35 119.7 25.8 1.4e-18 66.8 9.7 2.5 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.23 EMR61662.1 - 5.9e-17 62.1 0.0 1.3e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Porin_3 PF01459.22 EMR61663.1 - 1.1e-77 261.2 0.0 1.3e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin RF-1 PF00472.20 EMR61664.1 - 2.4e-24 85.5 0.4 3.9e-24 84.8 0.4 1.2 1 0 0 1 1 1 1 RF-1 domain Trypsin_2 PF13365.6 EMR61665.1 - 2.6e-21 77.1 0.1 3.6e-16 60.4 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 EMR61665.1 - 1.3e-14 54.2 0.6 7.1e-09 35.9 0.0 3.7 3 0 0 3 3 3 2 PDZ domain PDZ_1 PF12812.7 EMR61665.1 - 3.3e-14 52.6 0.0 2.4e-06 27.5 0.0 3.6 3 0 0 3 3 3 2 PDZ-like domain PDZ PF00595.24 EMR61665.1 - 5.5e-09 36.2 0.0 3.7e-05 24.0 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 EMR61665.1 - 1.6e-08 34.3 0.2 1.6e-05 24.7 0.1 3.6 3 0 0 3 3 3 1 PDZ domain Peptidase_S7 PF00949.21 EMR61665.1 - 0.00043 20.1 0.1 0.001 18.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Trypsin PF00089.26 EMR61665.1 - 0.01 15.7 0.0 0.054 13.3 0.0 2.1 2 1 0 2 2 2 0 Trypsin Peptidase_S46 PF10459.9 EMR61665.1 - 0.023 13.4 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.16 EMR61665.1 - 0.053 13.0 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF31) SPC22 PF04573.12 EMR61666.1 - 8.6e-40 136.0 1.6 1.3e-38 132.1 1.6 2.0 1 1 0 1 1 1 1 Signal peptidase subunit Actin PF00022.19 EMR61667.1 - 2.4e-150 500.7 0.0 9.3e-150 498.8 0.0 1.7 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 EMR61668.1 - 7.1e-61 205.9 0.0 5.7e-60 202.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR61668.1 - 1e-22 80.7 0.0 7.6e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR61668.1 - 2.5e-06 27.0 0.0 5.4e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EMR61668.1 - 0.00015 21.7 0.3 0.0037 17.2 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 EMR61668.1 - 0.0049 17.1 0.1 0.0075 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Choline_kinase PF01633.20 EMR61668.1 - 0.047 13.3 0.0 0.14 11.8 0.0 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EMR61668.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EMR61668.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp_protease_2 PF13650.6 EMR61669.1 - 0.054 14.2 0.0 0.12 13.1 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease 6PF2K PF01591.18 EMR61670.1 - 3.2e-48 164.0 0.1 1.2e-47 162.1 0.1 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EMR61670.1 - 4.9e-21 75.3 1.0 3.8e-20 72.4 1.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ZnuA PF01297.17 EMR61670.1 - 0.078 12.4 0.0 0.19 11.1 0.0 1.7 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic SPT_ssu-like PF11779.8 EMR61671.1 - 8.1e-23 79.8 3.5 1e-22 79.4 3.5 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Ferlin_C PF16165.5 EMR61671.1 - 0.19 11.7 0.6 0.24 11.3 0.6 1.1 1 0 0 1 1 1 0 Ferlin C-terminus Acetyltransf_1 PF00583.25 EMR61672.1 - 5.5e-06 26.6 0.0 7.1e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EMR61672.1 - 0.00042 20.4 0.2 0.0017 18.4 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR61672.1 - 0.0027 17.6 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR61672.1 - 0.0093 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR61672.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Haem_degrading PF03928.14 EMR61673.1 - 4.2e-34 117.1 0.0 5.2e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Peptidase_C48 PF02902.19 EMR61674.1 - 8.6e-26 91.1 0.0 2.3e-25 89.7 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NmrA PF05368.13 EMR61676.1 - 2e-13 50.5 0.0 2.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR61676.1 - 3.3e-07 30.4 0.0 3.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 EMR61676.1 - 0.0037 17.3 0.0 0.0052 16.8 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Cation_ATPase_C PF00689.21 EMR61677.1 - 5.5e-48 163.1 0.5 5.5e-48 163.1 0.5 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EMR61677.1 - 2.2e-35 121.8 1.1 2.2e-35 121.8 1.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EMR61677.1 - 1.4e-22 79.5 0.0 2.9e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMR61677.1 - 1.2e-14 55.1 0.3 1.3e-13 51.7 0.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMR61677.1 - 2e-06 27.4 0.1 1.7e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMR61677.1 - 3.5e-06 26.9 0.4 7.8e-06 25.8 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 EMR61677.1 - 0.64 8.8 7.0 0.043 12.6 1.2 2.0 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG Ribosomal_L5_C PF00673.21 EMR61678.1 - 1.3e-18 66.9 0.0 3.5e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EMR61678.1 - 2.5e-11 43.7 0.2 5.2e-11 42.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 ketoacyl-synt PF00109.26 EMR61679.1 - 6.2e-69 232.4 0.0 1.1e-68 231.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EMR61679.1 - 9.3e-54 182.1 0.0 3.4e-53 180.2 0.0 2.1 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.21 EMR61679.1 - 1e-48 166.5 0.0 1.7e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EMR61679.1 - 2.5e-44 151.7 0.0 4.7e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EMR61679.1 - 1.4e-20 74.7 0.0 7.9e-19 69.0 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ketoacyl-synt_C PF02801.22 EMR61679.1 - 8.9e-17 61.2 0.0 2e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 EMR61679.1 - 1.2e-16 60.9 0.0 6.2e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EMR61679.1 - 6.7e-15 55.6 0.0 1.9e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EMR61679.1 - 7e-15 55.5 0.1 6.6e-14 52.3 0.1 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EMR61679.1 - 4.9e-14 52.5 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR61679.1 - 4.1e-10 40.2 0.0 1.7e-09 38.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR61679.1 - 3.8e-09 37.1 0.0 2.3e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR61679.1 - 4.8e-09 36.2 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EMR61679.1 - 7.7e-09 35.3 0.4 2.3e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 EMR61679.1 - 3.3e-08 33.8 0.2 2.3e-07 31.1 0.1 2.5 3 0 0 3 3 3 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EMR61679.1 - 1.8e-05 24.2 0.1 4.5e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EMR61679.1 - 5e-05 23.1 0.0 0.00017 21.4 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase Thiolase_N PF00108.23 EMR61679.1 - 0.00063 19.2 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EMR61679.1 - 0.017 15.0 1.0 0.29 11.0 0.7 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 3Beta_HSD PF01073.19 EMR61679.1 - 0.038 13.0 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PCMT PF01135.19 EMR61679.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HORMA PF02301.18 EMR61680.1 - 5.4e-14 52.3 0.0 7e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain MFS_1 PF07690.16 EMR61681.1 - 1.2e-53 182.3 30.1 1.5e-53 182.0 30.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61681.1 - 2e-15 56.6 6.7 2e-15 56.6 6.7 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EMR61681.1 - 5.4e-09 35.8 6.3 5.4e-09 35.8 6.3 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EMR61681.1 - 0.73 8.2 10.7 0.66 8.3 9.5 1.5 1 1 0 1 1 1 0 Transmembrane secretion effector Prefoldin_2 PF01920.20 EMR61682.1 - 7.4e-27 93.4 3.3 8.2e-27 93.2 3.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4757 PF15949.5 EMR61682.1 - 0.0042 17.6 1.0 0.0065 17.0 1.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4757) TACC_C PF05010.14 EMR61682.1 - 0.0059 16.4 4.2 0.0074 16.1 4.2 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ALIX_LYPXL_bnd PF13949.6 EMR61682.1 - 0.0075 15.6 1.3 0.0096 15.3 1.3 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF915 PF06028.11 EMR61682.1 - 0.011 15.1 0.2 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2205 PF10224.9 EMR61682.1 - 0.013 15.4 3.5 0.11 12.5 1.0 2.2 2 0 0 2 2 2 0 Short coiled-coil protein BAR_3 PF16746.5 EMR61682.1 - 0.021 14.5 1.0 0.028 14.1 1.0 1.1 1 0 0 1 1 1 0 BAR domain of APPL family Syntaxin-6_N PF09177.11 EMR61682.1 - 0.025 15.1 3.0 0.23 12.0 0.5 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CagS PF16707.5 EMR61682.1 - 0.025 14.6 0.3 0.032 14.2 0.3 1.1 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Golgin_A5 PF09787.9 EMR61682.1 - 0.032 13.7 2.1 0.038 13.5 2.1 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tho2 PF11262.8 EMR61682.1 - 0.034 13.4 3.4 0.16 11.1 3.4 1.8 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PhaP_Bmeg PF09602.10 EMR61682.1 - 0.034 14.1 4.0 0.34 10.8 4.0 2.0 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Phage_Mu_Gam PF07352.12 EMR61682.1 - 0.042 13.8 3.4 0.053 13.4 3.4 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Imm9 PF15587.6 EMR61682.1 - 0.056 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 9 Prefoldin PF02996.17 EMR61682.1 - 0.07 13.0 6.5 19 5.2 6.5 2.3 1 1 0 1 1 1 0 Prefoldin subunit SAS-6_N PF16531.5 EMR61682.1 - 0.089 13.4 0.2 0.12 12.9 0.2 1.3 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal HBB PF06777.11 EMR61682.1 - 0.09 12.4 0.5 0.19 11.4 0.5 1.6 1 1 0 1 1 1 0 Helical and beta-bridge domain TPR_MLP1_2 PF07926.12 EMR61682.1 - 0.092 12.8 5.6 0.72 9.9 2.2 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SLATT_1 PF18181.1 EMR61682.1 - 0.11 12.4 1.0 0.21 11.5 0.7 1.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 V_ATPase_I PF01496.19 EMR61682.1 - 0.12 10.3 0.6 0.14 10.1 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAP_central PF04928.17 EMR61682.1 - 0.19 10.7 1.0 0.37 9.7 1.0 1.5 1 1 0 1 1 1 0 Poly(A) polymerase central domain DUF2089 PF09862.9 EMR61682.1 - 0.21 11.7 1.7 0.41 10.7 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2089) Fzo_mitofusin PF04799.13 EMR61682.1 - 0.26 10.8 3.3 1.1 8.8 2.9 1.9 1 1 0 1 1 1 0 fzo-like conserved region TMPIT PF07851.13 EMR61682.1 - 0.33 10.1 2.4 0.41 9.9 2.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4351 PF14261.6 EMR61682.1 - 1.6 8.9 5.5 0.17 11.9 0.5 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) OmpH PF03938.14 EMR61682.1 - 2.6 8.4 9.7 4.2 7.7 4.6 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) p450 PF00067.22 EMR61685.1 - 9.7e-39 133.4 0.7 1.3e-38 133.0 0.7 1.2 1 0 0 1 1 1 1 Cytochrome P450 PCP_red PF08369.10 EMR61685.1 - 0.048 13.9 0.3 0.12 12.6 0.3 1.6 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit FliH PF02108.16 EMR61685.1 - 0.059 13.4 1.1 8.8 6.4 0.4 3.2 2 2 1 3 3 3 0 Flagellar assembly protein FliH Nop14 PF04147.12 EMR61686.1 - 0.025 12.8 12.0 0.023 12.9 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EMR61686.1 - 0.49 9.8 17.9 0.61 9.5 17.9 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EMR61686.1 - 1 8.4 24.6 1.5 7.9 24.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 EMR61686.1 - 1.1 9.2 17.4 1.4 8.9 17.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid_p PF12226.8 EMR61686.1 - 1.6 7.8 16.6 2 7.5 16.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 EMR61686.1 - 2.1 6.6 13.6 2.3 6.4 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Anoctamin PF04547.12 EMR61687.1 - 2.8e-113 379.2 9.9 3.5e-113 378.8 9.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF373 PF04123.13 EMR61687.1 - 0.22 10.9 1.0 0.39 10.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) GRASP55_65 PF04495.14 EMR61688.1 - 1.6e-44 151.6 0.0 2.1e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EMR61688.1 - 0.057 13.3 0.0 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 PDZ domain Cmc1 PF08583.10 EMR61689.1 - 2.5e-18 65.8 3.7 2.9e-18 65.6 3.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Rho_GDI PF02115.17 EMR61690.1 - 5e-62 209.1 0.2 4.2e-61 206.1 0.2 2.1 2 0 0 2 2 2 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.28 EMR61691.1 - 9.8e-37 127.4 0.4 1.3e-36 127.0 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMR61691.1 - 0.035 14.5 0.2 0.088 13.3 0.2 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain p450 PF00067.22 EMR61692.1 - 1.7e-39 135.9 0.0 2.1e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Carn_acyltransf PF00755.20 EMR61693.1 - 7.7e-203 675.3 0.0 8.7e-203 675.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CBFD_NFYB_HMF PF00808.23 EMR61694.1 - 3.9e-29 100.7 1.0 5.2e-29 100.3 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMR61694.1 - 7.2e-06 26.4 0.0 1.1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EMR61694.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EMR61694.1 - 0.0019 18.1 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EMR61694.1 - 0.0057 16.8 0.0 0.0076 16.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EMR61694.1 - 0.032 14.7 0.1 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Mon1 PF03164.14 EMR61695.1 - 3.7e-154 513.7 0.0 4.4e-154 513.4 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 PPARgamma_N PF12577.8 EMR61695.1 - 0.072 13.7 0.1 0.19 12.4 0.1 1.7 1 0 0 1 1 1 0 PPAR gamma N-terminal region WSC PF01822.19 EMR61696.1 - 4.8e-11 42.7 3.1 4.8e-11 42.7 3.1 2.1 2 0 0 2 2 2 1 WSC domain Glyco_hydro_16 PF00722.21 EMR61696.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 Tmemb_14 PF03647.13 EMR61697.1 - 6.3e-22 78.1 10.6 7.3e-22 77.9 10.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 EMR61697.1 - 0.04 14.2 1.6 0.2 11.9 1.6 2.1 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 PfkB PF00294.24 EMR61698.1 - 3.6e-15 56.0 0.1 8.1e-10 38.5 0.4 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase UPF0164 PF03687.13 EMR61698.1 - 0.23 10.2 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) KilA-N PF04383.13 EMR61699.1 - 0.00071 19.4 0.0 0.012 15.5 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain IBN_N PF03810.19 EMR61700.1 - 1.5e-10 40.8 0.0 1.5e-09 37.6 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EMR61700.1 - 0.00067 19.7 0.0 0.43 10.6 0.0 3.6 4 0 0 4 4 4 2 Exportin 1-like protein Peptidase_S49 PF01343.18 EMR61700.1 - 0.067 13.1 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 HEAT PF02985.22 EMR61700.1 - 0.14 12.5 0.4 82 3.9 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat FMO-like PF00743.19 EMR61701.1 - 7.5e-09 34.5 0.0 5.4e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMR61701.1 - 1.8e-08 33.9 0.0 1.6e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMR61701.1 - 6.1e-06 25.7 0.0 1.8e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR61701.1 - 1.5e-05 25.1 0.0 5.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR61701.1 - 5e-05 22.7 0.0 0.00022 20.6 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR61701.1 - 0.0024 17.2 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Thioredoxin PF00085.20 EMR61702.1 - 6.4e-64 212.4 5.7 1.8e-31 108.2 0.2 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 EMR61702.1 - 5.6e-50 169.8 2.0 2.3e-37 128.7 0.6 3.5 2 2 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 EMR61702.1 - 6.2e-11 42.0 2.6 7.7e-11 41.6 0.6 2.1 2 1 0 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.6 EMR61702.1 - 1e-10 41.6 0.1 1e-05 25.6 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EMR61702.1 - 3.8e-09 36.8 0.0 0.017 15.5 0.0 4.5 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 EMR61702.1 - 5.3e-09 35.8 0.8 0.0015 17.9 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EMR61702.1 - 2.2e-08 34.5 2.1 0.0016 18.9 0.1 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 EMR61702.1 - 1.8e-07 31.1 0.9 0.0044 16.9 0.2 3.2 2 1 1 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 EMR61702.1 - 8.1e-06 25.6 4.3 0.07 12.8 0.0 3.6 3 1 0 3 3 3 2 Redoxin ERp29_N PF07912.13 EMR61702.1 - 0.0001 22.4 0.1 2.6 8.2 0.0 3.6 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.6 EMR61702.1 - 0.011 15.7 1.1 0.053 13.6 0.1 2.6 3 0 0 3 3 3 0 Thioredoxin domain DSBA PF01323.20 EMR61702.1 - 0.02 14.7 0.1 8.8 6.1 0.0 3.6 3 1 1 4 4 4 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EMR61702.1 - 0.023 14.9 4.5 1.3 9.1 0.1 3.7 3 2 0 3 3 3 0 Thioredoxin Methyltransf_15 PF09445.10 EMR61703.1 - 4.6e-32 110.9 0.0 9.2e-32 109.9 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase K_channel_TID PF07941.11 EMR61703.1 - 1.8 9.1 12.4 0.49 10.9 4.2 2.7 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain CAP_N PF01213.19 EMR61704.1 - 8.2e-120 400.1 2.9 1.6e-119 399.1 2.9 1.5 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EMR61704.1 - 1.2e-56 190.6 0.1 1.7e-56 190.2 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal MCM PF00493.23 EMR61705.1 - 1.2e-97 325.4 0.2 2.3e-97 324.5 0.2 1.5 1 0 0 1 1 1 1 MCM P-loop domain adh_short PF00106.25 EMR61705.1 - 5.4e-32 110.8 1.5 1.1e-21 77.2 0.6 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MCM_OB PF17207.3 EMR61705.1 - 3.2e-30 104.6 0.0 7.2e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain adh_short_C2 PF13561.6 EMR61705.1 - 5.3e-25 88.3 0.1 1.8e-23 83.3 0.1 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MCM_lid PF17855.1 EMR61705.1 - 5.7e-24 84.3 0.8 1.3e-23 83.2 0.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMR61705.1 - 1.3e-10 41.8 0.0 3.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain KR PF08659.10 EMR61705.1 - 1.5e-10 41.3 1.2 7.1e-10 39.1 1.2 2.1 1 1 0 1 1 1 1 KR domain Mg_chelatase PF01078.21 EMR61705.1 - 9.4e-07 28.4 0.0 9.8e-06 25.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EMR61705.1 - 0.0043 16.9 0.0 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMR61705.1 - 0.018 14.8 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Ndc1_Nup PF09531.10 EMR61705.1 - 3.4 6.3 5.5 5.7 5.5 5.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DAD PF02109.16 EMR61706.1 - 4e-49 165.5 3.4 5e-49 165.1 3.4 1.1 1 0 0 1 1 1 1 DAD family Clp1 PF06807.14 EMR61706.1 - 0.075 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 TPPII_N PF12583.8 EMR61706.1 - 6.3 7.4 10.3 9.4 6.8 10.3 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal A_deaminase PF00962.22 EMR61707.1 - 0.092 12.0 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Adenosine/AMP deaminase PI31_Prot_N PF11566.8 EMR61708.1 - 4.8e-64 215.1 0.0 6e-64 214.8 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EMR61708.1 - 4.1e-15 56.7 20.0 4.1e-15 56.7 20.0 3.8 4 1 0 4 4 4 1 PI31 proteasome regulator NmrA PF05368.13 EMR61709.1 - 1.6e-21 77.0 0.1 1.9e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR61709.1 - 6.2e-16 58.8 0.0 1.1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMR61709.1 - 6.5e-07 29.7 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMR61709.1 - 7e-05 22.9 1.0 0.00014 21.9 0.3 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EMR61709.1 - 0.011 16.6 0.4 0.025 15.4 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.19 EMR61709.1 - 0.022 13.8 0.0 0.05 12.6 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMR61709.1 - 0.049 13.1 0.1 0.22 10.9 0.1 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EMR61709.1 - 0.12 13.0 1.4 0.68 10.5 0.3 2.6 2 2 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_L32e PF01655.18 EMR61710.1 - 2.5e-46 156.6 0.5 2.9e-46 156.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 zf-C6H2 PF15801.5 EMR61711.1 - 0.011 16.1 10.5 0.088 13.1 4.8 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EMR61711.1 - 0.011 15.8 5.9 0.011 15.8 5.9 2.4 2 0 0 2 2 2 0 MYND finger Prok-RING_4 PF14447.6 EMR61711.1 - 0.016 15.0 5.2 0.14 12.0 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_Tnp_IS1595 PF12760.7 EMR61711.1 - 0.02 14.9 6.3 0.48 10.5 1.0 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain YacG PF03884.14 EMR61711.1 - 0.025 14.3 1.5 0.23 11.2 0.4 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG MPTase-PolyVal PF18818.1 EMR61711.1 - 0.054 13.6 1.1 0.77 9.8 0.1 2.6 2 1 0 2 2 2 0 Metallopeptidase superfamily domain Ecl1 PF12855.7 EMR61711.1 - 0.11 13.7 0.3 0.11 13.7 0.3 2.1 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Trm112p PF03966.16 EMR61711.1 - 0.22 12.1 1.7 31 5.2 0.5 3.1 2 1 1 3 3 3 0 Trm112p-like protein Rhodanese_C PF12368.8 EMR61711.1 - 1.8 9.0 11.2 0.52 10.7 1.0 2.5 2 0 0 2 2 2 0 Rhodanase C-terminal DUF3138 PF11336.8 EMR61711.1 - 3.1 6.3 5.1 4.4 5.8 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Histone_HNS PF00816.21 EMR61711.1 - 8.3 7.3 9.1 3.6 8.5 2.1 3.2 4 0 0 4 4 4 0 H-NS histone family HAD PF12710.7 EMR61712.1 - 6.8e-22 78.8 0.1 1e-21 78.2 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR61712.1 - 1.8e-15 57.8 1.7 3.1e-15 57.0 1.7 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMR61712.1 - 1.2e-08 35.0 0.1 1.2e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR61712.1 - 0.0035 17.4 0.1 4.7 7.3 0.0 3.0 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 EMR61712.1 - 0.0075 15.8 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Put_Phosphatase PF06888.12 EMR61712.1 - 0.11 11.9 0.1 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Acid_PPase PF12689.7 EMR61712.1 - 0.19 11.5 0.0 0.62 9.9 0.1 1.8 2 0 0 2 2 2 0 Acid Phosphatase Tim44 PF04280.15 EMR61713.1 - 9.5e-09 35.5 0.1 1.3e-07 31.8 0.1 2.0 1 1 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 EMR61713.1 - 3.5e-07 29.5 0.0 4.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein GPI-anchored PF10342.9 EMR61714.1 - 3.4e-05 24.5 0.6 0.00021 22.0 0.6 2.2 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UPF0016 PF01169.19 EMR61715.1 - 1.1e-40 137.8 24.6 1.5e-20 73.3 7.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 rhaM PF05336.13 EMR61716.1 - 5.5e-36 122.9 0.2 6.5e-36 122.7 0.2 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase SLS PF14611.6 EMR61717.1 - 7.3e-46 156.8 17.3 8.3e-46 156.6 13.4 2.7 2 1 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Nop14 PF04147.12 EMR61718.1 - 3 5.9 12.3 4.7 5.3 12.3 1.2 1 0 0 1 1 1 0 Nop14-like family Autophagy_N PF03986.13 EMR61719.1 - 3.1e-45 153.5 1.9 3.6e-45 153.3 0.1 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EMR61719.1 - 5.2e-16 57.8 0.6 9.7e-16 57.0 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EMR61719.1 - 8.4e-16 58.3 0.2 1.6e-15 57.4 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Thioredoxin PF00085.20 EMR61720.1 - 4.6e-07 29.8 0.0 6.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EMR61720.1 - 0.00035 20.3 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF953 PF06110.11 EMR61720.1 - 0.0075 15.9 0.1 0.035 13.7 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 EMR61720.1 - 0.016 15.6 0.0 0.093 13.2 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EMR61720.1 - 0.018 14.8 0.0 0.056 13.2 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 EMR61720.1 - 0.042 14.0 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Ribosomal_L37e PF01907.19 EMR61721.1 - 2.7e-27 94.7 12.9 3.8e-27 94.2 12.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EMR61721.1 - 0.0074 16.3 1.8 0.011 15.7 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EMR61721.1 - 0.091 12.5 2.4 6.7 6.6 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 EMR61721.1 - 0.21 11.6 1.2 0.28 11.2 1.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1258 PF06869.12 EMR61721.1 - 0.94 8.9 4.0 0.7 9.3 2.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) GTP_EFTU PF00009.27 EMR61722.1 - 1.4e-54 184.6 0.0 2.1e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMR61722.1 - 1.1e-41 141.6 0.0 2.4e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMR61722.1 - 2.4e-14 53.5 1.5 2.4e-14 53.5 1.5 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMR61722.1 - 0.00094 19.2 0.1 0.023 14.8 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EMR61722.1 - 0.11 12.4 3.1 0.077 12.9 0.7 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 MAGE PF01454.19 EMR61723.1 - 8e-69 231.6 0.0 1.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 MAGE family SF3b10 PF07189.11 EMR61724.1 - 8.3e-38 128.4 0.0 9.5e-38 128.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Sugar_tr PF00083.24 EMR61725.1 - 9e-46 156.7 8.1 1.4e-36 126.3 0.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR61725.1 - 2.5e-11 43.1 7.4 1.6e-10 40.5 7.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Xan_ur_permease PF00860.20 EMR61726.1 - 1.1e-23 83.5 31.4 9.7e-23 80.5 27.2 2.8 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.20 EMR61726.1 - 2e-06 26.9 13.7 3e-05 22.9 13.7 2.2 1 1 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 EMR61726.1 - 0.014 15.8 4.1 0.014 15.8 4.1 3.6 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF4956 PF16316.5 EMR61726.1 - 0.034 13.8 8.0 0.47 10.1 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4956) EOS1 PF12326.8 EMR61727.1 - 2.6e-15 56.8 12.1 2.6e-15 56.8 12.1 1.8 1 1 1 2 2 2 1 N-glycosylation protein PAPS_reduct PF01507.19 EMR61728.1 - 1.2e-42 145.9 0.0 1.8e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Adaptin_N PF01602.20 EMR61729.1 - 5.2e-115 385.0 0.5 6.7e-115 384.6 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EMR61729.1 - 1.4e-56 190.8 2.7 2.7e-56 189.9 2.7 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EMR61729.1 - 1.3e-32 112.3 0.1 3.7e-32 110.8 0.1 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EMR61729.1 - 1.5e-18 67.0 1.7 2.1e-12 47.2 0.0 5.6 2 1 4 6 6 6 2 HEAT repeats Cnd1 PF12717.7 EMR61729.1 - 1.3e-06 28.5 9.9 0.056 13.5 0.1 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EMR61729.1 - 0.00057 20.3 0.7 1.2 10.0 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 EMR61729.1 - 0.008 15.8 4.7 0.018 14.6 0.1 3.1 3 1 1 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 EMR61729.1 - 0.039 14.1 0.6 3.7 7.8 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF5010 PF16402.5 EMR61729.1 - 0.06 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) HEAT PF02985.22 EMR61729.1 - 0.13 12.6 9.0 2.1 8.8 0.2 5.3 5 0 0 5 5 5 0 HEAT repeat SUI1 PF01253.22 EMR61730.1 - 4.2e-27 94.5 1.9 5.6e-27 94.1 1.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 EMR61730.1 - 0.099 12.9 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain NUDIX PF00293.28 EMR61733.1 - 3.6e-08 33.5 0.1 5.7e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain YbjQ_1 PF01906.17 EMR61734.1 - 7.4e-05 23.3 3.7 0.00015 22.3 3.7 1.5 1 0 0 1 1 1 1 Putative heavy-metal-binding SR-25 PF10500.9 EMR61734.1 - 0.0067 16.1 6.3 0.0068 16.0 6.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pox_Ag35 PF03286.14 EMR61734.1 - 0.016 15.0 7.3 0.019 14.7 7.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MAP17 PF15807.5 EMR61734.1 - 0.031 14.5 4.8 0.032 14.5 4.8 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NCKAP5 PF15246.6 EMR61734.1 - 0.064 12.9 9.1 0.073 12.7 9.1 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Connexin PF00029.19 EMR61734.1 - 0.084 12.6 1.2 0.088 12.6 1.2 1.1 1 0 0 1 1 1 0 Connexin CPP1-like PF11833.8 EMR61734.1 - 0.1 12.3 2.1 0.14 11.8 2.1 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Coilin_N PF15862.5 EMR61734.1 - 0.11 12.4 8.0 0.12 12.2 8.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus Menin PF05053.13 EMR61734.1 - 0.12 10.7 4.5 0.13 10.6 4.5 1.1 1 0 0 1 1 1 0 Menin Tau95_N PF17682.1 EMR61734.1 - 0.13 12.4 6.7 0.19 11.9 6.7 1.2 1 0 0 1 1 1 0 Tau95 Triple barrel domain Apis_Csd PF11671.8 EMR61734.1 - 0.15 12.1 8.6 0.19 11.7 8.6 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein Orf78 PF06024.12 EMR61734.1 - 0.15 12.4 3.7 0.21 11.9 3.7 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF3464 PF11947.8 EMR61734.1 - 0.24 11.1 7.1 0.35 10.6 7.1 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 dsRBD2 PF17842.1 EMR61734.1 - 0.34 11.1 5.1 0.41 10.9 5.1 1.1 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 NARP1 PF12569.8 EMR61734.1 - 0.55 9.1 9.3 0.62 8.9 9.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1168 PF06658.12 EMR61734.1 - 0.61 9.9 17.8 0.84 9.5 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) NPR3 PF03666.13 EMR61734.1 - 0.89 8.3 7.9 1 8.1 7.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 OAD_gamma PF04277.13 EMR61734.1 - 0.97 10.1 3.5 1.6 9.3 3.5 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Nup_retrotrp_bd PF10599.9 EMR61734.1 - 1.2 9.9 7.7 1.9 9.2 4.0 2.1 2 0 0 2 2 2 0 Retro-transposon transporting motif Presenilin PF01080.17 EMR61734.1 - 1.2 7.8 3.8 1.3 7.7 3.8 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 EMR61734.1 - 1.8 8.6 8.3 2.8 8.0 8.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PAP2 PF01569.21 EMR61735.1 - 9.6e-24 83.7 0.6 2.5e-23 82.4 0.6 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 EMR61735.1 - 0.0025 18.3 1.2 0.0055 17.2 0.1 2.1 2 1 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 EMR61735.1 - 0.019 14.6 9.9 1.4 8.6 9.9 2.5 1 1 0 1 1 1 0 PAP2 superfamily K_channel_TID PF07941.11 EMR61735.1 - 0.66 10.5 6.0 7.9 7.0 6.4 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF3093 PF11292.8 EMR61735.1 - 3.5 7.9 9.2 0.53 10.5 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Methyltr_RsmB-F PF01189.17 EMR61736.1 - 1.8e-77 259.5 0.0 3.9e-77 258.4 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EMR61736.1 - 8.1e-08 32.7 0.0 2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF DUF2431 PF10354.9 EMR61736.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_31 PF13847.6 EMR61736.1 - 0.044 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cofilin_ADF PF00241.20 EMR61737.1 - 2.2e-25 88.8 0.0 2.4e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Blt1 PF12754.7 EMR61738.1 - 1.1e-37 129.6 0.1 1.5e-37 129.2 0.1 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 EMR61738.1 - 1.3e-17 63.1 1.7 2.1e-17 62.4 1.7 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 EMR61738.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Cutinase PF01083.22 EMR61739.1 - 1.1e-40 139.5 0.1 1.4e-40 139.2 0.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EMR61739.1 - 2e-06 27.6 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 EMR61739.1 - 0.06 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 EMR61739.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) VirJ PF06057.11 EMR61739.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) zinc_ribbon_10 PF10058.9 EMR61740.1 - 7.4e-19 67.2 0.1 1.3e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein zf-RanBP PF00641.18 EMR61740.1 - 0.46 9.8 3.1 0.25 10.7 0.5 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others LapA_dom PF06305.11 EMR61741.1 - 6.9 6.6 5.7 11 5.9 5.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GRIP PF01465.20 EMR61742.1 - 4e-15 55.4 0.1 8.5e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 EMR61742.1 - 3.8e-05 22.7 128.7 0.0025 16.8 13.9 7.5 3 2 3 7 7 7 6 Spc7 kinetochore protein APG6_N PF17675.1 EMR61742.1 - 9.7e-05 22.9 160.6 0.1 13.1 2.8 10.6 2 2 7 10 10 10 5 Apg6 coiled-coil region GAS PF13851.6 EMR61742.1 - 0.0002 20.8 126.5 0.056 12.8 18.3 8.7 3 2 5 8 8 8 6 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 EMR61742.1 - 0.00056 19.9 0.3 0.00056 19.9 0.3 13.0 6 3 5 13 13 11 2 Centrosome localisation domain of PPC89 Fez1 PF06818.15 EMR61742.1 - 0.0013 19.2 120.0 0.12 12.9 13.7 7.7 2 1 4 6 6 5 2 Fez1 Nup54 PF13874.6 EMR61742.1 - 0.0038 17.3 7.8 0.0038 17.3 7.8 7.7 3 3 1 5 5 4 1 Nucleoporin complex subunit 54 Cep57_CLD PF14073.6 EMR61742.1 - 0.0044 17.1 24.3 0.0044 17.1 24.3 8.5 6 3 3 9 9 8 2 Centrosome localisation domain of Cep57 CENP-F_leu_zip PF10473.9 EMR61742.1 - 0.0062 16.6 136.9 0.012 15.7 8.3 8.9 3 2 7 10 10 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 EMR61742.1 - 0.0087 16.1 17.0 0.0087 16.1 17.0 11.1 3 2 5 9 9 8 3 Designed helical repeat protein 10 domain Filament PF00038.21 EMR61742.1 - 0.027 14.0 125.4 0.76 9.3 2.1 9.6 3 2 5 8 8 8 0 Intermediate filament protein SlyX PF04102.12 EMR61742.1 - 0.037 14.7 0.3 0.037 14.7 0.3 13.0 7 3 3 12 12 12 0 SlyX Phage_GP20 PF06810.11 EMR61742.1 - 0.73 9.6 116.6 0.032 14.0 7.6 9.3 4 2 5 10 10 9 0 Phage minor structural protein GP20 MscS_porin PF12795.7 EMR61742.1 - 0.97 8.9 133.1 0.16 11.5 14.8 7.6 3 2 3 7 7 6 0 Mechanosensitive ion channel porin domain DUF4200 PF13863.6 EMR61742.1 - 8.9 6.7 132.0 0.68 10.4 14.3 9.3 3 2 3 8 8 8 0 Domain of unknown function (DUF4200) RCR PF12273.8 EMR61743.1 - 5e-20 72.3 19.2 9.8e-20 71.4 19.2 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 EMR61743.1 - 0.0034 17.1 1.1 0.0044 16.7 1.1 1.3 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Hum_adeno_E3A PF05393.11 EMR61743.1 - 0.021 14.8 1.9 0.031 14.2 1.9 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4381 PF14316.6 EMR61743.1 - 0.13 12.5 2.9 0.19 12.0 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RNA_pol_Rpb2_6 PF00562.28 EMR61744.1 - 2.6e-113 379.1 0.4 3.3e-113 378.7 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EMR61744.1 - 4.1e-29 101.6 0.0 6.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EMR61744.1 - 5.3e-28 97.0 0.0 1.1e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EMR61744.1 - 4.5e-25 88.4 0.0 8.5e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EMR61744.1 - 2.1e-23 82.1 0.0 4.2e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EMR61744.1 - 2.1e-16 60.1 0.0 5.4e-15 55.6 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Arf PF00025.21 EMR61745.1 - 7.3e-42 142.8 0.0 8.7e-42 142.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EMR61745.1 - 5.2e-18 65.2 0.0 6.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR61745.1 - 6.1e-14 52.3 0.0 9.4e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EMR61745.1 - 3.1e-06 26.6 0.0 1.1e-05 24.8 0.0 1.9 2 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EMR61745.1 - 1.2e-05 25.3 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EMR61745.1 - 2.7e-05 23.7 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMR61745.1 - 0.00013 21.4 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EMR61745.1 - 0.035 13.6 0.0 0.08 12.5 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF1979 PF09322.10 EMR61745.1 - 0.079 12.9 0.5 9.8 6.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) PduV-EutP PF10662.9 EMR61745.1 - 0.16 11.7 0.0 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 EMR61745.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PTR2 PF00854.21 EMR61746.1 - 4.7e-57 193.6 4.9 6.2e-57 193.2 4.9 1.1 1 0 0 1 1 1 1 POT family DUF1195 PF06708.11 EMR61746.1 - 0.42 10.4 2.5 14 5.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) ADH_N PF08240.12 EMR61748.1 - 3.1e-30 104.2 1.0 3.1e-30 104.2 1.0 2.7 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR61748.1 - 1.5e-15 57.4 0.0 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR61748.1 - 1.6e-06 27.7 0.1 4.7e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 EMR61748.1 - 0.096 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_N PF08240.12 EMR61749.1 - 1.3e-30 105.5 0.5 1.3e-30 105.5 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR61749.1 - 8e-24 84.1 0.5 1.4e-23 83.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR61749.1 - 4e-08 33.0 0.3 4.5e-07 29.6 0.3 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMR61749.1 - 0.00016 22.7 0.0 0.00069 20.7 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EMR61749.1 - 0.034 14.8 0.0 0.068 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cas_csx3 PF09620.10 EMR61749.1 - 0.073 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Aminotran_1_2 PF00155.21 EMR61750.1 - 1.4e-36 126.4 0.0 1.8e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMR61750.1 - 9.2e-06 25.2 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EMR61750.1 - 6.4e-05 21.7 0.0 9.2e-05 21.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMR61750.1 - 0.21 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Na_Ca_ex PF01699.24 EMR61751.1 - 5.9e-16 58.8 13.6 2.7e-14 53.4 9.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MotA_activ PF09114.10 EMR61751.1 - 0.018 15.1 0.3 0.035 14.2 0.3 1.4 1 0 0 1 1 1 0 Transcription factor MotA, activation domain DUF4577 PF15145.6 EMR61751.1 - 0.067 13.2 4.7 2.8 8.0 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) DUF3792 PF12670.7 EMR61751.1 - 1.8 8.8 10.9 0.14 12.3 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) Sugar_tr PF00083.24 EMR61752.1 - 2.3e-75 254.2 16.7 2.7e-75 254.0 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR61752.1 - 2.1e-19 69.7 30.3 1.4e-12 47.2 16.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR61752.1 - 0.00019 20.2 21.6 0.0012 17.5 1.0 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 EMR61752.1 - 0.0017 17.7 10.8 0.031 13.6 1.8 2.4 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Acyl_transf_1 PF00698.21 EMR61753.1 - 2.6e-47 161.9 0.0 5.6e-47 160.8 0.0 1.5 2 0 0 2 2 2 1 Acyl transferase domain DUF1729 PF08354.10 EMR61753.1 - 1e-33 116.7 1.5 6.2e-28 97.7 0.6 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.19 EMR61753.1 - 4.3e-28 97.3 0.0 9.1e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_meander PF17951.1 EMR61753.1 - 0.14 12.0 2.5 0.16 11.8 0.6 2.0 2 0 0 2 2 2 0 Fatty acid synthase meander beta sheet domain DUF1993 PF09351.10 EMR61754.1 - 5.3e-43 147.0 0.0 5.9e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DeoC PF01791.9 EMR61755.1 - 3.2e-09 36.8 0.2 4.6e-09 36.2 0.2 1.3 1 0 0 1 1 1 1 DeoC/LacD family aldolase Ank_2 PF12796.7 EMR61757.1 - 8.9e-31 106.3 5.7 3.6e-13 49.9 0.3 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR61757.1 - 5.8e-21 74.6 6.9 2.3e-07 31.2 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR61757.1 - 1.7e-18 66.5 4.2 1.4e-07 31.6 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR61757.1 - 5.7e-15 53.9 1.4 0.00058 20.1 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EMR61757.1 - 5.4e-12 45.6 9.3 5.3e-05 23.5 0.2 4.3 4 0 0 4 4 4 3 Ankyrin repeat Cellulase PF00150.18 EMR61759.1 - 6.4e-28 98.0 1.6 8.4e-28 97.6 1.6 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_transf_90 PF05686.12 EMR61760.1 - 3.7e-13 49.2 0.5 1.6e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Methyltransf_23 PF13489.6 EMR61761.1 - 1.1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR61761.1 - 2.8e-06 27.9 0.0 1.2e-05 26.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR61761.1 - 4.2e-05 23.4 0.0 8.7e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR61761.1 - 0.00063 20.5 0.0 0.0018 19.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR61761.1 - 0.0041 17.7 0.0 0.01 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain YmgD PF16456.5 EMR61761.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 YmgD protein DUF1479 PF07350.12 EMR61762.1 - 1.2e-163 544.8 0.0 1.4e-163 544.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EMR61762.1 - 0.00012 22.4 0.3 0.43 10.8 0.2 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) RrnaAD PF00398.20 EMR61763.1 - 1.1e-05 24.6 0.0 2.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase F-box-like PF12937.7 EMR61764.1 - 0.00023 21.0 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR61764.1 - 0.0018 18.1 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cnd1_N PF12922.7 EMR61765.1 - 0.019 14.8 0.2 0.019 14.8 0.2 2.1 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Ferritin PF00210.24 EMR61765.1 - 0.033 14.1 4.0 0.028 14.3 2.1 1.8 1 1 0 1 1 1 0 Ferritin-like domain p450 PF00067.22 EMR61766.1 - 1.4e-33 116.4 0.0 1.8e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KR PF08659.10 EMR61767.1 - 9.7e-54 182.0 0.0 1.9e-53 181.1 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EMR61767.1 - 1.2e-40 139.6 0.0 2.3e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EMR61767.1 - 1.9e-25 90.0 0.1 5.1e-25 88.6 0.1 1.7 1 1 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 EMR61767.1 - 1.4e-19 70.7 0.0 3.6e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR61767.1 - 1.9e-12 47.3 0.0 4.5e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EMR61767.1 - 2.9e-12 46.7 0.0 1.9e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR61767.1 - 3e-12 47.7 0.0 1.4e-10 42.4 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EMR61767.1 - 4.3e-11 43.0 0.1 1.3e-10 41.5 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EMR61767.1 - 1e-10 42.1 0.0 5.9e-10 39.7 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 EMR61767.1 - 1.8e-09 37.4 0.4 4.8e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 EMR61767.1 - 2.9e-08 33.5 0.0 6.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EMR61767.1 - 5.3e-07 30.2 0.0 1.9e-06 28.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR61767.1 - 5.2e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EMR61767.1 - 1.7e-05 24.7 0.0 4.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase Polysacc_synt_2 PF02719.15 EMR61767.1 - 0.00045 19.4 0.0 0.00071 18.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMR61767.1 - 0.0048 16.3 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ubie_methyltran PF01209.18 EMR61767.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 EMR61767.1 - 0.021 14.0 0.0 0.077 12.1 0.0 1.8 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent YbbR PF07949.12 EMR61767.1 - 0.064 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 YbbR-like protein p450 PF00067.22 EMR61768.1 - 1.7e-32 112.8 0.0 8.5e-17 61.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 NAD_binding_10 PF13460.6 EMR61769.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF3638 PF12340.8 EMR61770.1 - 2.5e-96 321.4 0.1 3.9e-96 320.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EMR61770.1 - 1.7e-19 68.9 0.7 3.2e-19 68.0 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) AMP-binding PF00501.28 EMR61772.1 - 1.1e-53 182.4 0.0 3.3e-53 180.8 0.0 1.7 1 1 1 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 EMR61772.1 - 6.8e-26 90.9 0.0 1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain p450 PF00067.22 EMR61775.1 - 5.5e-40 137.5 0.0 1.2e-39 136.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.28 EMR61776.1 - 2.2e-21 76.5 0.0 3.3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR61776.1 - 1e-12 47.9 0.1 2.1e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EMR61777.1 - 1.9e-30 106.1 0.0 3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR61777.1 - 7.5e-12 45.1 0.0 3e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMR61777.1 - 0.0033 17.1 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 SGL PF08450.12 EMR61778.1 - 7e-10 38.9 0.0 3.3e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EMR61778.1 - 0.0029 17.7 0.0 0.0077 16.3 0.0 1.7 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 EMR61778.1 - 0.023 14.9 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 Arylesterase NHL PF01436.21 EMR61778.1 - 0.03 14.4 0.1 3.7 7.8 0.0 2.8 2 0 0 2 2 2 0 NHL repeat EthD PF07110.11 EMR61779.1 - 0.0042 18.2 0.1 0.018 16.2 0.1 1.9 1 1 0 1 1 1 1 EthD domain SURF6 PF04935.12 EMR61780.1 - 1.4e-50 171.8 44.5 1.4e-50 171.8 44.5 4.1 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EMR61780.1 - 8.6e-05 23.1 2.4 8.6e-05 23.1 2.4 7.3 4 2 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 Tannase PF07519.11 EMR61781.1 - 1.2e-60 205.8 0.1 1.3e-60 205.7 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase RTA1 PF04479.13 EMR61782.1 - 7.3e-62 208.6 17.4 1.6e-61 207.5 17.4 1.6 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 EMR61782.1 - 0.00066 19.8 2.5 0.0012 18.9 2.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ALAD PF00490.21 EMR61783.1 - 3.8e-119 397.6 0.0 5.2e-119 397.1 0.0 1.2 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Peptidase_M28 PF04389.17 EMR61784.1 - 6e-41 140.3 0.1 8.6e-41 139.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMR61784.1 - 1.7e-10 40.7 0.4 3.9e-10 39.6 0.4 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EMR61784.1 - 0.0044 16.7 0.1 0.0091 15.7 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Root_cap PF06830.11 EMR61784.1 - 0.1 12.7 0.0 18 5.5 0.0 2.8 3 0 0 3 3 3 0 Root cap DUF3645 PF12359.8 EMR61784.1 - 0.14 11.6 0.3 11 5.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) Fungal_lectin_2 PF18647.1 EMR61786.1 - 0.00032 21.1 0.2 0.00036 20.9 0.2 1.2 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin Y_phosphatase3 PF13350.6 EMR61788.1 - 5.6e-55 186.8 0.0 7.8e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EMR61788.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EMR61788.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EMR61788.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EMR61788.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PPR_2 PF13041.6 EMR61790.1 - 1.2e-09 38.2 0.0 0.084 13.1 0.0 4.9 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 EMR61790.1 - 3.6e-05 23.8 0.0 0.91 9.6 0.0 3.7 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EMR61790.1 - 0.01 15.2 0.0 22 4.3 0.0 3.5 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EMR61790.1 - 0.021 15.0 6.1 15 6.1 0.1 4.7 4 0 0 4 4 4 0 PPR repeat ATP13 PF12921.7 EMR61790.1 - 0.087 12.7 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase expression PPR_1 PF12854.7 EMR61790.1 - 5.7 6.7 7.2 1.5 8.5 0.1 3.8 5 0 0 5 5 5 0 PPR repeat MFS_1 PF07690.16 EMR61791.1 - 9.8e-15 54.3 53.7 9.8e-15 54.3 53.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1230 PF06799.11 EMR61791.1 - 9.7 6.3 6.6 1.8 8.7 0.8 2.3 3 0 0 3 3 3 0 Conserved in the green lineage and diatoms 27 Ribosomal_S18 PF01084.20 EMR61792.1 - 4.9e-11 42.7 0.1 1.1e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Amidohydro_3 PF07969.11 EMR61793.1 - 7.7e-29 101.5 0.1 6e-15 55.7 0.0 2.5 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EMR61793.1 - 0.00064 19.1 0.0 0.004 16.5 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family Glyco_transf_34 PF05637.12 EMR61794.1 - 1.2e-69 234.7 0.0 1.5e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EMR61794.1 - 0.00079 19.1 0.0 0.45 10.0 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 DUF1447 PF07288.11 EMR61794.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) RINGv PF12906.7 EMR61796.1 - 5e-11 42.5 2.6 8.5e-10 38.6 0.7 2.3 2 0 0 2 2 2 1 RING-variant domain Marek_A PF02124.15 EMR61796.1 - 0.053 13.3 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A EI24 PF07264.11 EMR61796.1 - 0.088 13.0 0.2 0.088 13.0 0.2 1.8 1 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) FixS PF03597.15 EMR61796.1 - 9.5 6.0 11.1 0.11 12.2 2.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type FAD_binding_3 PF01494.19 EMR61797.1 - 2e-76 257.6 0.0 2.6e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMR61797.1 - 6.8e-36 123.8 0.0 2e-35 122.3 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EMR61797.1 - 7.2e-05 22.2 0.0 0.025 13.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR61797.1 - 0.0041 17.7 0.0 0.015 15.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EMR61797.1 - 0.01 15.4 1.8 0.044 13.4 0.0 2.4 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 EMR61797.1 - 0.014 15.0 0.3 0.71 9.4 0.1 2.4 1 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR61797.1 - 0.028 13.2 0.0 0.061 12.0 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 EMR61797.1 - 0.034 14.4 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR61797.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.6 EMR61797.1 - 0.12 12.9 0.1 0.33 11.5 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Pyridoxal_deC PF00282.19 EMR61798.1 - 1.3e-15 57.1 0.0 1.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EMR61798.1 - 0.00032 19.8 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMR61798.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sugar_tr PF00083.24 EMR61799.1 - 2.2e-90 303.7 24.2 2.6e-90 303.5 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR61799.1 - 3.9e-25 88.5 48.8 4.5e-21 75.2 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CdvA PF18822.1 EMR61800.1 - 0.012 15.5 1.1 0.014 15.2 1.1 1.1 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Tropomyosin_1 PF12718.7 EMR61800.1 - 0.012 15.7 3.6 0.015 15.4 3.6 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF4201 PF13870.6 EMR61800.1 - 0.04 13.6 3.4 0.048 13.4 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4355 PF14265.6 EMR61800.1 - 0.1 12.9 2.4 0.13 12.5 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) XhlA PF10779.9 EMR61800.1 - 0.15 12.3 1.1 0.26 11.5 1.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA PspA_IM30 PF04012.12 EMR61800.1 - 0.31 10.6 4.8 0.2 11.2 2.2 1.7 1 1 1 2 2 2 0 PspA/IM30 family Stc1 PF12898.7 EMR61801.1 - 3.4e-20 72.4 5.0 4.7e-20 71.9 5.0 1.2 1 0 0 1 1 1 1 Stc1 domain BCDHK_Adom3 PF10436.9 EMR61803.1 - 4e-75 251.1 0.0 6.4e-75 250.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EMR61803.1 - 8.2e-13 48.8 0.0 1.5e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMR61803.1 - 0.056 13.3 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5594 PF18057.1 EMR61804.1 - 0.1 12.5 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5594) RRM_1 PF00076.22 EMR61804.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_I_TF PF04090.12 EMR61805.1 - 9.6e-12 44.8 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor rRNA_methylase PF06962.12 EMR61805.1 - 0.079 12.9 0.3 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Putative rRNA methylase ETC_C1_NDUFA5 PF04716.14 EMR61806.1 - 3.8e-26 90.7 0.1 1.8e-23 82.1 0.0 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region DUF4188 PF13826.6 EMR61806.1 - 0.043 14.2 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) MIF4G PF02854.19 EMR61807.1 - 2.8e-40 138.2 0.0 1.7e-26 93.2 0.1 3.6 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EMR61807.1 - 2.5e-21 76.8 9.5 9.3e-12 45.8 2.7 3.7 3 1 1 4 4 4 2 Up-frameshift suppressor 2 CBP4 PF07960.11 EMR61807.1 - 0.013 15.3 0.0 0.054 13.4 0.0 2.1 1 0 0 1 1 1 0 CBP4 Arginosuc_synth PF00764.19 EMR61808.1 - 8.8e-13 48.3 0.0 6.7e-09 35.5 0.0 2.0 1 1 1 2 2 2 2 Arginosuccinate synthase MFS_1 PF07690.16 EMR61809.1 - 7e-38 130.5 52.9 7e-38 130.5 52.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61809.1 - 2.9e-12 46.2 18.8 2.9e-12 46.2 18.8 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter ADH_zinc_N PF00107.26 EMR61809.1 - 1.3e-07 31.6 0.1 2.6e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR61809.1 - 0.025 14.4 0.0 0.14 12.1 0.0 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain RRM_1 PF00076.22 EMR61810.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1998 PF09369.10 EMR61811.1 - 3e-24 85.6 0.2 6.6e-24 84.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) DEAD PF00270.29 EMR61811.1 - 9.1e-15 54.9 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR61811.1 - 1.8e-10 41.2 0.0 1.7e-09 38.0 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR61811.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ran_BP1 PF00638.18 EMR61812.1 - 1.2e-18 67.6 0.1 2.3e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 RanBP1 domain RTA1 PF04479.13 EMR61813.1 - 9.8e-31 107.0 4.0 1.4e-30 106.4 4.0 1.2 1 0 0 1 1 1 1 RTA1 like protein Mo-co_dimer PF03404.16 EMR61814.1 - 4.9e-62 208.0 0.1 8.7e-62 207.2 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EMR61814.1 - 1.5e-36 125.6 0.0 2.8e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 EMR61814.1 - 4.1e-32 110.5 0.0 6.9e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EMR61814.1 - 1.1e-19 70.3 0.0 2.3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 EMR61814.1 - 6e-14 52.6 0.0 2.8e-12 47.3 0.0 2.6 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMR61814.1 - 0.066 13.3 0.1 0.32 11.1 0.0 1.9 1 1 0 2 2 2 0 Ferric reductase NAD binding domain BAR_2 PF10455.9 EMR61815.1 - 1.2e-58 198.5 0.2 1.9e-58 197.9 0.2 1.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EMR61815.1 - 2.7e-23 82.9 1.1 2.9e-22 79.5 1.1 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EMR61815.1 - 0.0075 16.0 0.1 0.05 13.3 0.0 2.2 2 0 0 2 2 2 1 BAR domain of APPL family Metal_resist PF13801.6 EMR61815.1 - 0.026 14.7 2.3 0.13 12.4 0.0 2.9 3 0 0 3 3 3 0 Heavy-metal resistance YdjC PF04794.12 EMR61815.1 - 0.087 12.8 0.7 0.15 12.0 0.4 1.5 1 1 0 1 1 1 0 YdjC-like protein Chitin_synth_2 PF03142.15 EMR61816.1 - 1.5e-21 76.6 4.2 2.7e-21 75.8 2.8 2.9 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EMR61816.1 - 2.7e-16 60.1 8.7 2.7e-16 60.1 8.7 2.4 2 2 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMR61816.1 - 8.8e-13 48.7 0.0 3e-12 46.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMR61816.1 - 0.015 15.1 0.4 6.2 6.6 0.2 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Squash PF00299.18 EMR61816.1 - 0.23 11.5 0.8 0.79 9.8 0.4 2.0 2 0 0 2 2 2 0 Squash family serine protease inhibitor 4HBT_3 PF13622.6 EMR61817.1 - 3e-42 145.6 0.7 3.5e-42 145.4 0.7 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily VSP PF03302.13 EMR61818.1 - 0.0021 17.0 3.4 0.0025 16.7 0.1 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein SKG6 PF08693.10 EMR61818.1 - 0.014 14.8 0.4 0.035 13.5 0.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CoatB PF10389.9 EMR61818.1 - 0.044 13.6 0.0 0.044 13.6 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage coat protein B RELT PF12606.8 EMR61818.1 - 0.23 10.5 1.3 0.36 9.9 1.3 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 MFS_1 PF07690.16 EMR61819.1 - 1.1e-35 123.2 47.5 1.1e-35 123.2 47.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily ACC_epsilon PF13822.6 EMR61819.1 - 0.13 13.0 0.0 0.36 11.5 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit FKBP_C PF00254.28 EMR61820.1 - 1.1e-23 83.4 0.0 1.4e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BUD22 PF09073.10 EMR61821.1 - 0.0019 17.6 19.7 0.0019 17.6 19.7 2.2 2 0 0 2 2 2 2 BUD22 Acylphosphatase PF00708.18 EMR61822.1 - 1.6e-19 70.1 1.0 3.9e-19 68.8 1.0 1.6 1 1 0 1 1 1 1 Acylphosphatase Lactamase_B_3 PF13483.6 EMR61823.1 - 0.0001 22.2 0.0 0.00027 20.9 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EMR61823.1 - 0.00015 21.3 0.2 0.00077 19.0 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Na_trans_assoc PF06512.13 EMR61823.1 - 0.016 15.5 0.3 0.016 15.5 0.3 2.9 2 1 0 3 3 3 0 Sodium ion transport-associated HDA2-3 PF11496.8 EMR61823.1 - 0.4 9.8 5.2 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Peptidase_S49_N PF08496.10 EMR61823.1 - 1.1 9.3 10.7 3.8 7.6 10.7 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NapB PF03892.14 EMR61823.1 - 1.2 9.2 11.9 0.14 12.2 6.4 2.2 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) HA2 PF04408.23 EMR61824.1 - 1.6e-22 79.8 1.4 1.4e-21 76.8 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EMR61824.1 - 1.3e-17 63.9 0.0 6.7e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EMR61824.1 - 1.2e-12 48.1 0.0 3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMR61824.1 - 3.6e-08 33.4 0.0 7.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMR61824.1 - 5.7e-06 26.6 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EMR61824.1 - 3.9e-05 23.1 0.0 7.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EMR61824.1 - 7.1e-05 23.2 0.1 0.00017 22.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMR61824.1 - 8.8e-05 22.3 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EMR61824.1 - 0.0015 18.6 0.0 0.64 10.0 0.0 2.8 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EMR61824.1 - 0.0033 16.5 0.0 0.0078 15.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EMR61824.1 - 0.0041 17.1 0.1 0.0084 16.1 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.22 EMR61824.1 - 0.008 15.8 0.3 0.019 14.6 0.3 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EMR61824.1 - 0.021 15.2 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EMR61824.1 - 0.022 14.3 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EMR61824.1 - 0.028 14.5 0.2 0.2 11.7 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMR61824.1 - 0.21 11.7 3.1 0.17 12.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EMR61824.1 - 0.36 11.3 2.7 0.43 11.1 0.0 2.5 4 0 0 4 4 3 0 ABC transporter ChaC PF04752.12 EMR61826.1 - 1.8e-36 125.9 0.0 3.5e-36 124.9 0.0 1.4 1 1 0 1 1 1 1 ChaC-like protein Orf78 PF06024.12 EMR61827.1 - 0.018 15.3 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 EMR61827.1 - 0.023 15.6 0.0 0.032 15.1 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 EMR61827.1 - 0.036 14.5 0.6 0.06 13.8 0.6 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein OAD_gamma PF04277.13 EMR61827.1 - 0.058 14.0 0.0 0.13 12.9 0.0 1.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4834 PF16118.5 EMR61827.1 - 0.074 14.0 0.0 0.11 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Phage_holin_2_4 PF16082.5 EMR61827.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF2207 PF09972.9 EMR61827.1 - 0.14 10.9 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 EMR61827.1 - 0.15 11.9 0.2 0.4 10.6 0.0 1.7 1 1 1 2 2 2 0 TMEM154 protein family DUF1180 PF06679.12 EMR61827.1 - 0.16 12.4 1.4 0.25 11.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) RCDG1 PF15725.5 EMR61827.1 - 6 7.4 10.3 1.7 9.1 6.6 1.9 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein TPP_enzyme_C PF02775.21 EMR61828.1 - 1.8e-46 157.7 0.3 4.4e-46 156.4 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMR61828.1 - 1.1e-38 132.1 0.3 2.8e-38 130.8 0.3 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain SNF2_N PF00176.23 EMR61828.1 - 1.6e-05 23.8 0.0 2.4e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR61828.1 - 2.1e-05 24.8 0.1 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HpcH_HpaI PF03328.14 EMR61829.1 - 7.7e-37 126.6 0.0 6.2e-35 120.3 0.0 2.0 2 0 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EMR61829.1 - 1.2e-10 41.1 0.0 6.6e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEPcase_2 PF14010.6 EMR61829.1 - 0.058 11.9 0.0 0.085 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase PCI PF01399.27 EMR61830.1 - 2.3e-15 57.0 2.4 3e-14 53.4 0.0 3.1 3 1 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 EMR61830.1 - 3e-09 36.4 0.6 8.4e-09 35.0 0.6 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Vps35 PF03635.17 EMR61830.1 - 0.00072 18.2 0.1 0.0013 17.3 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DnaG_DnaB_bind PF08278.11 EMR61830.1 - 0.017 15.7 0.7 0.044 14.4 0.2 2.0 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding TRAF_BIRC3_bd PF16673.5 EMR61831.1 - 1.9 8.3 3.8 1.2 9.0 0.7 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain RRM_1 PF00076.22 EMR61832.1 - 1.1e-17 63.6 0.0 1.5e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR61832.1 - 0.00043 20.3 0.0 0.00064 19.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EMR61832.1 - 0.0038 17.2 0.0 0.0046 16.9 0.0 1.1 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EMR61832.1 - 0.032 14.3 0.0 0.037 14.1 0.0 1.0 1 0 0 1 1 1 0 RNA binding motif GalKase_gal_bdg PF10509.9 EMR61833.1 - 3.7e-19 68.0 0.0 6e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EMR61833.1 - 2.8e-14 53.3 0.4 6e-13 49.0 0.1 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EMR61833.1 - 6.8e-13 48.7 2.2 2.1e-12 47.1 2.2 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain RPA_C PF08784.11 EMR61833.1 - 0.06 14.0 0.2 0.14 12.8 0.2 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Sigma70_r4 PF04545.16 EMR61833.1 - 0.077 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EMR61833.1 - 0.098 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 eIF2_C PF09173.11 EMR61834.1 - 2.4e-34 117.4 0.3 5.6e-34 116.3 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EMR61834.1 - 1.7e-23 83.2 1.0 1e-22 80.6 1.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EMR61834.1 - 5.6e-11 42.7 0.2 1.1e-10 41.7 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMR61834.1 - 0.0041 17.2 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR61834.1 - 0.048 13.6 0.3 0.48 10.3 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EMR61834.1 - 0.075 13.1 0.5 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Hep_59 PF07052.11 EMR61835.1 - 1.2e-09 38.9 2.6 1.2e-09 38.9 2.6 2.9 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 ADK PF00406.22 EMR61837.1 - 1.2e-43 148.8 0.0 2e-43 148.1 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EMR61837.1 - 2.4e-34 118.7 0.0 4.3e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMR61837.1 - 1.1e-07 32.5 0.0 1.7e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMR61837.1 - 4.4e-05 23.7 0.1 0.00037 20.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EMR61837.1 - 0.0003 20.5 0.1 0.1 12.2 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase WD40 PF00400.32 EMR61838.1 - 1.6e-15 57.2 8.2 0.014 16.3 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 EMR61838.1 - 3.5e-08 32.5 3.2 4.2e-05 22.4 1.5 3.5 2 2 2 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EMR61838.1 - 3.7e-07 30.4 0.2 0.0023 18.2 0.2 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 EMR61839.1 - 3.7e-53 180.6 0.0 4.8e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR61839.1 - 1.1e-24 87.1 0.0 3.6e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EMR61839.1 - 0.064 12.2 0.1 0.097 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EMR61839.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF5527 PF17665.1 EMR61840.1 - 0.11 12.1 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) DUF4231 PF14015.6 EMR61840.1 - 3.2 8.2 4.4 1.4 9.4 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) TMA7 PF09072.10 EMR61841.1 - 1.5e-24 86.6 22.5 1.7e-24 86.4 22.5 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Annexin PF00191.20 EMR61842.1 - 2.7e-71 235.6 4.5 3.3e-21 75.1 0.0 4.2 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 EMR61842.1 - 0.055 13.4 1.5 0.22 11.4 0.1 2.6 4 0 0 4 4 4 0 Myb DNA-binding like ABC_tran PF00005.27 EMR61844.1 - 6e-45 153.1 0.0 2.9e-26 92.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR61844.1 - 1.4e-35 123.2 15.4 3.3e-19 69.6 8.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EMR61844.1 - 5.1e-14 52.2 0.0 0.00015 21.2 0.0 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMR61844.1 - 3.8e-09 36.8 0.9 0.0066 16.3 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMR61844.1 - 1.4e-06 28.6 0.4 0.0081 16.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 EMR61844.1 - 4.7e-06 26.6 0.5 0.0025 17.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 EMR61844.1 - 2.6e-05 24.8 0.6 0.0067 16.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMR61844.1 - 0.00012 22.5 0.0 0.49 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EMR61844.1 - 0.00015 21.4 3.1 0.042 13.6 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EMR61844.1 - 0.00058 19.0 0.0 0.59 9.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.29 EMR61844.1 - 0.0012 19.3 0.0 6.3 7.2 0.0 3.5 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EMR61844.1 - 0.003 17.2 0.5 0.1 12.2 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EMR61844.1 - 0.003 16.9 0.7 2.4 7.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EMR61844.1 - 0.0043 17.0 0.2 2.7 7.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 EMR61844.1 - 0.005 16.6 0.7 1.7 8.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 EMR61844.1 - 0.006 16.7 2.4 0.008 16.3 0.9 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 EMR61844.1 - 0.0093 16.1 0.1 3 8.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMR61844.1 - 0.016 14.8 1.1 0.32 10.5 0.2 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EMR61844.1 - 0.018 14.0 0.1 2.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 EMR61844.1 - 0.026 14.6 0.0 0.49 10.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EMR61844.1 - 0.028 14.2 1.4 0.74 9.5 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 EMR61844.1 - 0.029 13.9 0.5 2.8 7.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EMR61844.1 - 0.038 14.2 0.0 13 6.1 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 EMR61844.1 - 0.052 12.7 0.1 9.1 5.4 0.0 2.9 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 EMR61844.1 - 0.082 12.2 3.4 0.66 9.3 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 EMR61844.1 - 0.089 12.2 0.0 9.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.6 EMR61844.1 - 0.13 12.9 0.0 18 5.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EMR61844.1 - 0.14 12.5 0.0 16 6.0 0.0 2.9 3 0 0 3 3 2 0 RNA helicase ATP_bind_1 PF03029.17 EMR61844.1 - 0.2 11.4 0.9 20 4.9 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 EMR61844.1 - 0.22 11.5 0.3 2.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 EMR61844.1 - 0.36 10.0 3.2 11 5.1 0.2 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) EF-hand_1 PF00036.32 EMR61845.1 - 1.3e-25 86.9 6.2 1.2e-06 27.7 0.1 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EMR61845.1 - 6.5e-22 77.8 6.4 5.5e-10 39.5 0.0 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EMR61845.1 - 3.9e-21 73.1 5.5 0.00012 21.7 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EMR61845.1 - 2.1e-19 69.1 7.4 2.1e-09 37.1 0.0 4.5 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EMR61845.1 - 1.9e-17 61.9 3.8 7.7e-05 22.0 0.2 4.5 4 0 0 4 4 4 4 EF hand DAO PF01266.24 EMR61846.1 - 5.7e-29 101.8 0.3 6.5e-29 101.6 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR61846.1 - 0.016 15.4 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR61846.1 - 0.15 11.2 0.0 0.56 9.4 0.0 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.11 EMR61846.1 - 0.24 10.9 0.0 0.71 9.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Cupin_2 PF07883.11 EMR61847.1 - 1.2e-09 37.7 0.1 2.5e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EMR61847.1 - 0.37 10.5 3.3 2.6 7.8 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF861) MobB PF03205.14 EMR61848.1 - 0.13 12.1 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MFS_1 PF07690.16 EMR61849.1 - 8.4e-32 110.5 37.1 8.4e-32 110.5 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61849.1 - 6.6e-11 41.7 29.2 1.2e-06 27.7 7.8 2.9 2 1 1 3 3 3 3 Sugar (and other) transporter Ank_2 PF12796.7 EMR61850.1 - 2e-14 53.9 0.0 0.0014 19.2 0.0 4.5 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR61850.1 - 1.8e-12 47.5 2.1 0.049 14.2 0.0 5.8 4 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EMR61850.1 - 3.5e-09 36.7 1.9 0.33 11.5 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 EMR61850.1 - 1.1e-08 34.6 5.0 0.78 10.5 0.0 8.2 10 0 0 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 EMR61850.1 - 0.005 17.1 3.3 1.8 9.0 0.0 5.0 5 2 1 6 6 6 1 Ankyrin repeats (many copies) adh_short PF00106.25 EMR61851.1 - 2.1e-18 66.5 0.7 4.7e-10 39.2 0.4 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR61851.1 - 7.2e-08 32.3 1.7 0.00057 19.5 1.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR61851.1 - 0.00014 21.8 0.2 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EMR61851.1 - 0.022 14.7 0.2 0.034 14.1 0.2 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pox_MCEL PF03291.16 EMR61852.1 - 2.3e-67 227.5 0.0 3.7e-44 151.2 0.0 3.1 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 EMR61852.1 - 3.9e-10 40.3 0.1 0.00022 21.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EMR61852.1 - 4.1e-08 33.9 0.0 0.0051 17.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EMR61852.1 - 3.7e-07 30.7 0.1 0.031 14.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EMR61852.1 - 0.00026 20.8 0.0 0.008 16.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR61852.1 - 0.00079 19.3 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EMR61852.1 - 0.0034 16.6 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family SWIRM-assoc_2 PF16496.5 EMR61852.1 - 0.45 9.3 5.1 0.71 8.7 4.7 1.5 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Ribosomal_60s PF00428.19 EMR61852.1 - 4.1 8.1 11.7 0.078 13.6 4.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein CCDC53 PF10152.9 EMR61852.1 - 8.1 6.8 6.8 2.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Amidase PF01425.21 EMR61853.1 - 6.9e-87 292.3 0.0 9.9e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 Amidase CPSase_L_D2 PF02786.17 EMR61853.1 - 8.9e-64 214.9 0.0 1.5e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EMR61853.1 - 1e-41 141.9 0.6 1.5e-40 138.1 0.0 2.9 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EMR61853.1 - 5.1e-24 84.5 0.0 1.7e-23 82.8 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EMR61853.1 - 6.4e-12 45.4 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 EMR61853.1 - 0.0034 17.0 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EMR61853.1 - 0.0072 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Fungal_trans PF04082.18 EMR61854.1 - 1.5e-09 37.3 2.8 1.1e-05 24.6 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR61854.1 - 1.7e-05 24.8 9.0 3e-05 24.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glycos_trans_3N PF02885.17 EMR61854.1 - 0.058 13.3 0.2 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Aminotran_1_2 PF00155.21 EMR61855.1 - 1.6e-34 119.7 0.0 2.3e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.9 EMR61856.1 - 1.6e-54 184.2 0.2 2.8e-54 183.4 0.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EMR61856.1 - 2.3e-14 53.8 0.0 5.3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain COesterase PF00135.28 EMR61857.1 - 1.7e-80 271.4 0.0 5.4e-80 269.7 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR61857.1 - 0.0045 16.9 0.1 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Gly_kinase PF02595.15 EMR61859.1 - 5.9e-117 390.8 1.3 7.8e-117 390.3 1.3 1.2 1 0 0 1 1 1 1 Glycerate kinase family SR-25 PF10500.9 EMR61859.1 - 0.26 10.9 3.6 0.4 10.3 3.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.16 EMR61860.1 - 3.4e-37 128.2 19.9 3.4e-37 128.2 19.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61860.1 - 9.4e-13 47.8 3.3 9.4e-13 47.8 3.3 2.7 3 2 1 4 4 4 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR61861.1 - 4.1e-36 124.6 29.3 5.4e-36 124.3 29.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR61861.1 - 8.4e-08 31.9 5.7 8.4e-08 31.9 5.7 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3176 PF11374.8 EMR61862.1 - 8.3e-20 71.0 4.1 2.1e-19 69.7 4.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) adh_short_C2 PF13561.6 EMR61863.1 - 1.8e-48 165.2 0.0 1.3e-33 116.6 0.0 2.8 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR61863.1 - 3.8e-28 98.3 0.0 3.9e-14 52.6 0.0 2.7 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR61863.1 - 2e-06 27.8 0.1 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 KR domain DUF1180 PF06679.12 EMR61863.1 - 0.0024 18.3 0.8 0.004 17.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) CDC45 PF02724.14 EMR61865.1 - 0.28 9.4 6.4 0.33 9.2 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 EMR61865.1 - 4.8 5.9 8.9 5.8 5.7 8.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain ATP_transf PF09830.9 EMR61866.1 - 3e-11 43.3 0.0 4.8e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Sugar_tr PF00083.24 EMR61867.1 - 5.7e-80 269.4 21.5 1.1e-49 169.6 11.7 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR61867.1 - 7.6e-15 54.7 13.6 7.6e-15 54.7 13.6 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3188 PF11384.8 EMR61867.1 - 0.039 13.6 1.1 0.039 13.6 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF2070 PF09843.9 EMR61867.1 - 2 6.6 9.4 8.3 4.6 6.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 EMR61868.1 - 1.9e-08 33.6 19.5 3.4e-08 32.8 19.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 EMR61868.1 - 0.015 15.6 0.5 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) zf-RanBP PF00641.18 EMR61868.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others NmrA PF05368.13 EMR61869.1 - 2e-11 43.9 0.0 2.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR61869.1 - 6.3e-10 39.2 0.0 8.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR61869.1 - 5.3e-05 22.8 0.0 8.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMR61869.1 - 0.00053 19.5 0.0 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR61869.1 - 0.0039 16.8 0.1 0.0076 15.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR61869.1 - 0.012 15.6 0.1 0.024 14.5 0.1 1.6 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 EMR61869.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMR61869.1 - 0.058 12.5 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_2 PF00891.18 EMR61870.1 - 4.2e-21 75.2 0.0 6.3e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 EMR61870.1 - 0.0049 16.7 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 MarR family Dimerisation2 PF16864.5 EMR61870.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain TrmB PF01978.19 EMR61870.1 - 0.088 12.7 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SRR1 PF07985.12 EMR61871.1 - 0.0005 20.0 0.0 0.00092 19.2 0.0 1.5 1 0 0 1 1 1 1 SRR1 HLH PF00010.26 EMR61872.1 - 2.5e-12 46.6 0.1 5e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TonB_N PF16031.5 EMR61872.1 - 0.02 15.4 5.5 0.02 15.4 5.5 3.1 2 1 1 3 3 3 0 TonB polyproline region Macoilin PF09726.9 EMR61872.1 - 2.6 6.5 20.0 0.13 10.7 10.8 2.1 2 0 0 2 2 2 0 Macoilin family TPR_12 PF13424.6 EMR61873.1 - 2.6e-14 53.3 5.2 1.1e-11 44.8 2.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMR61873.1 - 4.9e-10 39.0 7.2 0.0021 17.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-MYND PF01753.18 EMR61873.1 - 5.9e-10 39.1 8.5 1e-09 38.3 8.5 1.4 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.28 EMR61873.1 - 1.2e-09 37.6 6.5 3.9e-05 23.3 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR61873.1 - 1.1e-06 28.3 8.3 0.00042 20.2 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMR61873.1 - 1.6e-06 27.7 4.1 0.22 11.7 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMR61873.1 - 0.0017 18.4 4.3 0.024 14.8 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMR61873.1 - 0.0018 17.9 4.4 0.051 13.3 0.1 2.9 3 0 0 3 3 3 1 TPR repeat PPR PF01535.20 EMR61873.1 - 0.0027 17.8 0.1 1.4 9.3 0.0 3.3 3 0 0 3 3 3 1 PPR repeat TPR_19 PF14559.6 EMR61873.1 - 0.0051 17.3 8.2 0.043 14.3 3.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMR61873.1 - 0.022 15.5 13.8 1 10.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMR61873.1 - 0.15 12.7 18.9 0.087 13.5 6.3 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR61873.1 - 0.23 12.2 15.3 1 10.2 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMR61873.1 - 0.38 11.2 4.2 4.9 7.8 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Tropomyosin PF00261.20 EMR61875.1 - 0.0011 18.4 2.8 0.0023 17.3 2.8 1.5 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 EMR61875.1 - 0.0012 19.0 3.9 0.0037 17.4 3.9 1.8 1 1 0 1 1 1 1 Tropomyosin like GT-D PF08759.11 EMR61875.1 - 0.0029 17.3 0.0 0.033 13.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase GT-D fold PSII_Pbs27 PF13326.6 EMR61875.1 - 0.0079 16.5 0.4 0.066 13.5 0.2 2.1 2 0 0 2 2 2 1 Photosystem II Pbs27 FliD_C PF07195.12 EMR61875.1 - 0.012 15.1 0.2 1.7 8.0 0.7 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus AP1AR PF15745.5 EMR61875.1 - 0.014 15.1 1.0 0.024 14.3 1.0 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein PTRF_SDPR PF15237.6 EMR61875.1 - 0.033 13.8 1.4 0.066 12.8 1.4 1.4 1 0 0 1 1 1 0 PTRF/SDPR family DASH_Spc19 PF08287.11 EMR61875.1 - 0.053 13.4 2.2 0.14 12.1 2.2 1.7 1 0 0 1 1 1 0 Spc19 Dynactin_p22 PF07426.11 EMR61875.1 - 0.13 12.1 1.2 0.27 11.1 0.3 1.8 2 0 0 2 2 2 0 Dynactin subunit p22 CLZ PF16526.5 EMR61875.1 - 0.16 12.4 4.4 0.21 11.9 1.5 2.5 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4200 PF13863.6 EMR61875.1 - 0.28 11.6 5.3 0.2 12.1 2.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF573 PF04504.14 EMR61875.1 - 2.1 9.0 4.7 5.1 7.8 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function, DUF573 DUF5010_C PF18099.1 EMR61877.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 DUF5010 C-terminal domain CBFD_NFYB_HMF PF00808.23 EMR61879.1 - 1.3e-10 41.3 0.8 1.8e-10 40.9 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMR61879.1 - 1.7e-06 28.4 0.0 1.7e-06 28.4 0.0 2.9 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EMR61879.1 - 0.0022 18.1 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAFII28 PF04719.14 EMR61879.1 - 0.0059 16.7 0.0 0.032 14.3 0.0 2.0 2 0 0 2 2 2 1 hTAFII28-like protein conserved region CDC27 PF09507.10 EMR61879.1 - 0.1 12.0 29.6 0.19 11.1 29.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MFS_1 PF07690.16 EMR61881.1 - 7.2e-32 110.7 23.7 7.2e-32 110.7 23.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61881.1 - 1.8e-13 50.2 13.2 1.8e-13 50.2 13.2 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter DUF3593 PF12159.8 EMR61881.1 - 0.018 15.1 0.2 0.072 13.1 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Peroxidase_2 PF01328.17 EMR61882.1 - 3.2e-31 109.3 0.0 3.7e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 PCMT PF01135.19 EMR61884.1 - 1.9e-51 174.8 0.0 6.4e-18 65.3 0.0 3.0 3 0 0 3 3 3 3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EMR61884.1 - 4.9e-06 26.4 0.0 8.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EMR61884.1 - 0.00027 21.0 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR61884.1 - 0.0012 19.5 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR61884.1 - 0.0029 17.5 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR61884.1 - 0.012 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EMR61884.1 - 0.023 15.3 0.1 0.079 13.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 EMR61884.1 - 0.097 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 EMR61884.1 - 0.098 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NmrA PF05368.13 EMR61886.1 - 5.7e-34 117.7 0.0 7.3e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR61886.1 - 6.1e-25 88.2 0.0 1.9e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EMR61886.1 - 1.3e-05 24.8 0.0 3.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Amidoligase_2 PF12224.8 EMR61886.1 - 0.049 13.3 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme ADH_zinc_N PF00107.26 EMR61886.1 - 0.12 12.3 0.2 7.2 6.6 0.0 2.7 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Glyco_hydro_61 PF03443.14 EMR61887.1 - 5e-49 167.0 0.1 6.4e-49 166.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TPPII PF12580.8 EMR61887.1 - 0.2 11.1 0.0 1 8.8 0.0 1.9 2 0 0 2 2 2 0 Tripeptidyl peptidase II Peptidase_M43 PF05572.13 EMR61888.1 - 9.4e-12 45.1 0.1 1.4e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EMR61888.1 - 0.043 14.0 0.1 0.072 13.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Lactonase PF10282.9 EMR61889.1 - 3.3e-82 276.5 0.0 4.1e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF2370 PF10176.9 EMR61891.1 - 5.3e-90 301.0 0.0 6.5e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.27 EMR61892.1 - 2.3e-52 174.9 2.4 1.3e-19 69.8 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF4574 PF15141.6 EMR61892.1 - 0.13 12.2 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 adh_short PF00106.25 EMR61893.1 - 2.7e-15 56.3 0.0 3.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR61893.1 - 2.2e-10 40.7 0.0 3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMR61893.1 - 3.8e-08 33.2 0.0 6.4e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR61893.1 - 0.015 14.8 0.2 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR61893.1 - 0.095 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMR61893.1 - 0.097 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YkyA PF10368.9 EMR61894.1 - 0.063 12.9 0.1 0.094 12.4 0.1 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein HTH_Tnp_Tc5 PF03221.16 EMR61894.1 - 0.081 13.0 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain Complex1_LYR PF05347.15 EMR61894.1 - 0.082 13.0 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) 5_nucleotid PF05761.14 EMR61894.1 - 0.13 11.2 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 5' nucleotidase family DUF1962 PF09227.10 EMR61895.1 - 9.6e-35 118.8 19.6 1.2e-34 118.5 19.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) Amidohydro_3 PF07969.11 EMR61896.1 - 1.6e-26 93.8 7.6 3.9e-26 92.6 7.6 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EMR61896.1 - 1.1e-05 24.9 0.6 0.019 14.3 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Ank_2 PF12796.7 EMR61897.1 - 3.5e-16 59.6 0.0 4.1e-07 30.5 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR61897.1 - 3.5e-14 53.0 0.3 4.7e-06 27.1 0.0 5.2 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 EMR61897.1 - 1.6e-11 44.1 0.2 0.0021 18.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EMR61897.1 - 2.7e-11 42.6 8.3 0.0024 18.2 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EMR61897.1 - 4.5e-09 36.4 1.8 0.016 15.5 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Spindle_Spc25 PF08234.12 EMR61898.1 - 2.2e-24 85.4 0.6 5e-24 84.3 0.1 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Atg14 PF10186.9 EMR61898.1 - 0.0026 16.9 6.3 0.0028 16.8 6.3 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EMR61898.1 - 0.011 14.6 7.5 0.017 14.0 7.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Tau95 PF09734.9 EMR61898.1 - 0.16 12.8 4.4 0.15 12.8 3.1 1.5 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF1664 PF07889.12 EMR61898.1 - 0.21 11.6 8.0 4.4 7.4 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EMR61898.1 - 1.6 8.0 12.3 2 7.7 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EMR61898.1 - 2.2 8.3 10.5 3.3 7.8 10.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 EMR61898.1 - 2.7 7.7 22.8 4.5 7.0 22.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.22 EMR61898.1 - 6.7 7.0 17.1 3.9 7.7 12.3 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4337 PF14235.6 EMR61898.1 - 8.4 6.5 11.0 14 5.8 11.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) adh_short PF00106.25 EMR61901.1 - 4.3e-30 104.6 0.0 4.8e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR61901.1 - 1.3e-25 90.3 0.0 1.5e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR61901.1 - 4.4e-11 43.0 0.0 5.4e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR61901.1 - 0.00027 20.5 0.0 0.00038 20.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMR61901.1 - 0.00044 20.2 0.0 0.00078 19.4 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR61901.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NFACT-R_1 PF05670.13 EMR61902.1 - 3.6e-26 91.9 0.1 4.9e-22 78.6 0.0 2.3 1 1 1 2 2 2 2 NFACT protein RNA binding domain Cyt-b5 PF00173.28 EMR61903.1 - 3.4e-10 39.9 0.0 5.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L26 PF16906.5 EMR61904.1 - 1.1e-38 131.5 3.4 1.6e-38 131.0 3.4 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EMR61904.1 - 4.4e-08 32.8 1.5 4.4e-08 32.8 1.5 1.8 2 0 0 2 2 2 1 KOW motif DUF4663 PF15668.5 EMR61904.1 - 0.034 13.2 0.7 0.039 13.0 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) DUF1223 PF06764.11 EMR61904.1 - 0.048 13.7 0.1 0.056 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) Ribosomal_L3 PF00297.22 EMR61905.1 - 8.3e-11 41.5 7.6 1.7e-09 37.1 4.5 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Acetyltransf_10 PF13673.7 EMR61906.1 - 2.7e-05 24.1 0.0 0.012 15.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EMR61906.1 - 0.00077 20.1 0.0 0.8 10.4 0.0 2.8 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR61906.1 - 0.0018 18.7 0.0 0.0073 16.7 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR61906.1 - 0.075 13.3 0.0 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family MOZART1 PF12554.8 EMR61907.1 - 1.3e-24 85.7 0.4 1.5e-24 85.5 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DHHA1 PF02272.19 EMR61907.1 - 0.088 13.2 0.1 0.11 13.0 0.1 1.1 1 0 0 1 1 1 0 DHHA1 domain DUF2661 PF10860.8 EMR61907.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2661) Coa1 PF08695.10 EMR61908.1 - 4.7e-40 136.0 0.0 6.1e-40 135.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Mito_carr PF00153.27 EMR61909.1 - 1.1e-66 220.7 4.6 2e-23 82.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 EMR61909.1 - 0.12 12.2 0.6 0.35 10.6 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Ribosomal_S25 PF03297.15 EMR61910.1 - 8.4e-32 109.4 9.9 2e-31 108.2 9.9 1.5 1 1 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 EMR61910.1 - 0.0045 16.5 0.1 0.0069 15.9 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EMR61910.1 - 0.019 14.8 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.12 EMR61910.1 - 0.021 14.6 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EMR61910.1 - 0.054 13.4 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 HTH domain HSP70 PF00012.20 EMR61911.1 - 2.5e-57 194.4 0.1 3.2e-57 194.1 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMR61911.1 - 9.3e-05 21.4 0.1 0.0015 17.4 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EMR61911.1 - 0.083 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain PITH PF06201.13 EMR61912.1 - 2.3e-43 148.1 0.0 3e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 EMR61912.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal CENP-X PF09415.10 EMR61913.1 - 8.7e-24 83.6 0.1 2.5e-23 82.2 0.1 1.8 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Cu_bind_like PF02298.17 EMR61914.1 - 0.069 13.2 0.2 0.38 10.8 0.2 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain DUF4680 PF15730.5 EMR61914.1 - 0.38 11.1 4.1 0.78 10.1 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) DUF1180 PF06679.12 EMR61914.1 - 1.3 9.5 4.1 1.9 8.9 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ribosomal_S7 PF00177.21 EMR61915.1 - 4.4e-37 127.0 2.3 5.7e-37 126.6 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ATP-synt_G PF04718.15 EMR61916.1 - 2.7e-35 121.2 2.4 3.5e-35 120.8 0.6 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit SipA_VBS PF17985.1 EMR61916.1 - 0.0007 19.3 0.2 0.03 14.2 0.0 3.3 3 0 0 3 3 3 1 SipA vinculin binding site YtxH PF12732.7 EMR61916.1 - 0.013 16.0 1.6 0.1 13.1 1.5 2.3 2 0 0 2 2 2 0 YtxH-like protein DUF3347 PF11827.8 EMR61916.1 - 0.067 13.4 4.6 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) FAM25 PF15825.5 EMR61916.1 - 1.1 9.7 9.7 1.6 9.1 5.3 2.3 1 1 1 2 2 2 0 FAM25 family SseC PF04888.12 EMR61916.1 - 2.6 7.6 15.0 6.7 6.2 14.9 1.7 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Ras PF00071.22 EMR61917.1 - 1e-48 165.0 0.0 1.2e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR61917.1 - 3.5e-29 101.5 0.0 5.3e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR61917.1 - 6.8e-11 41.9 0.0 8.2e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMR61917.1 - 0.00021 20.7 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMR61917.1 - 0.00024 20.7 0.0 0.00086 18.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMR61917.1 - 0.00057 20.0 0.0 0.0007 19.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EMR61917.1 - 0.0047 17.3 0.0 0.0067 16.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR61917.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMR61917.1 - 0.026 14.7 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMR61917.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 EMR61917.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EMR61917.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EMR61917.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Septin tRNA-synt_2b PF00587.25 EMR61918.1 - 4.7e-29 101.6 0.0 8.7e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EMR61918.1 - 1e-19 70.7 7.3 1.8e-19 69.9 7.3 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TssO PF17561.2 EMR61918.1 - 0.27 11.3 3.8 0.53 10.4 3.8 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssO NPV_P10 PF05531.12 EMR61918.1 - 1.1 9.7 3.2 3 8.4 3.2 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Ribosomal_S3Ae PF01015.18 EMR61919.1 - 2e-89 298.5 1.9 2.5e-89 298.2 1.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EMR61919.1 - 0.022 15.3 0.4 0.067 13.7 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 EMR61919.1 - 0.04 13.9 1.3 0.33 11.0 0.0 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO TipAS PF07739.13 EMR61919.1 - 0.1 13.1 0.0 1.3 9.6 0.0 2.3 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain TPMT PF05724.11 EMR61920.1 - 1.1e-34 120.0 0.0 1.5e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 EMR61920.1 - 2.6e-10 40.3 0.0 2.4e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR61920.1 - 4e-10 39.8 0.0 5.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR61920.1 - 9.9e-10 39.0 0.0 1.6e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR61920.1 - 4.6e-09 36.8 0.0 8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR61920.1 - 1.4e-07 32.1 0.0 3.8e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EMR61920.1 - 0.0031 17.0 0.0 0.0065 15.9 0.0 1.5 2 0 0 2 2 2 1 Tellurite resistance protein TehB AdoMet_MTase PF07757.13 EMR61920.1 - 0.026 14.9 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase CheR PF01739.18 EMR61920.1 - 0.09 12.2 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain N2227 PF07942.12 EMR61920.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein ADH_zinc_N_2 PF13602.6 EMR61920.1 - 0.15 13.1 0.0 0.25 12.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 EMR61920.1 - 0.23 11.4 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HMGL-like PF00682.19 EMR61921.1 - 2.7e-69 233.7 0.2 4.8e-66 223.0 0.2 2.1 2 0 0 2 2 2 2 HMGL-like Synaptobrevin PF00957.21 EMR61922.1 - 1.8e-14 53.3 0.9 2.7e-14 52.7 0.9 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EMR61922.1 - 6.8e-10 38.9 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Abhydrolase_1 PF00561.20 EMR61923.1 - 4.7e-26 92.0 0.0 5e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR61923.1 - 2.1e-15 57.9 0.0 2.7e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR61923.1 - 3.7e-09 36.2 0.1 5.7e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EMR61923.1 - 9.7e-07 28.7 0.2 0.032 13.9 0.1 2.1 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 EMR61923.1 - 0.0014 18.8 0.0 0.0022 18.2 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EMR61923.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF915 PF06028.11 EMR61923.1 - 0.057 12.7 0.0 6.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 EMR61923.1 - 0.093 11.4 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF3530 PF12048.8 EMR61923.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Ras PF00071.22 EMR61924.1 - 1.2e-13 51.0 0.0 1.3e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Tower PF09121.10 EMR61924.1 - 0.12 12.6 0.2 0.22 11.7 0.1 1.6 1 1 0 1 1 1 0 Tower Elf1 PF05129.13 EMR61925.1 - 5.8e-30 103.2 1.0 7.9e-30 102.7 1.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like PHD_4 PF16866.5 EMR61925.1 - 0.016 15.3 0.6 0.034 14.2 0.6 1.6 1 0 0 1 1 1 0 PHD-finger Zn-ribbon_8 PF09723.10 EMR61925.1 - 0.08 13.1 2.8 0.16 12.1 2.8 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EMR61925.1 - 0.087 12.8 1.1 0.17 11.9 1.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain UPRTase PF14681.6 EMR61926.1 - 4.3e-80 268.0 0.0 6e-80 267.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EMR61926.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GTP_CH_N PF12471.8 EMR61927.1 - 4.1e-80 268.1 0.0 3.1e-79 265.2 0.0 2.0 1 1 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EMR61927.1 - 1e-09 38.2 0.0 4.4e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 GTP cyclohydrolase II Ank_2 PF12796.7 EMR61928.1 - 2.2e-34 117.9 7.1 5.1e-09 36.6 0.4 5.9 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR61928.1 - 2.1e-25 88.8 10.9 1.9e-06 28.3 0.2 8.8 4 3 6 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 EMR61928.1 - 4.1e-24 83.9 9.5 0.0009 19.6 0.0 8.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 EMR61928.1 - 4.8e-21 72.6 12.1 0.00028 21.1 0.0 10.0 10 1 1 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 EMR61928.1 - 8.7e-20 70.5 13.0 0.019 15.3 0.0 8.1 8 1 1 9 9 9 5 Ankyrin repeats (many copies) F-box-like PF12937.7 EMR61928.1 - 6.2e-05 22.8 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like Sdh_cyt PF01127.22 EMR61929.1 - 2.2e-16 60.0 7.6 3.2e-16 59.5 7.6 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2-Hacid_dh_C PF02826.19 EMR61930.1 - 5.5e-36 123.6 0.0 6.2e-35 120.2 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR61930.1 - 1.6e-08 34.3 0.1 2.8e-08 33.5 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMR61930.1 - 1.1e-05 25.6 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMR61930.1 - 0.026 15.1 0.1 0.079 13.6 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 EMR61930.1 - 0.094 13.5 0.0 0.22 12.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold nec1 PF10379.9 EMR61930.1 - 0.14 11.7 0.5 0.24 10.9 0.5 1.3 1 0 0 1 1 1 0 Virulence protein nec1 EcKinase PF02958.20 EMR61931.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase TIP120 PF08623.10 EMR61932.1 - 1.5e-63 213.5 2.2 1.7e-59 200.3 0.0 4.5 3 1 0 4 4 4 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EMR61932.1 - 5.4e-12 45.9 23.9 0.015 15.6 0.1 9.9 9 4 1 10 10 10 3 HEAT repeats HEAT PF02985.22 EMR61932.1 - 6.9e-08 32.1 22.5 0.26 11.7 0.1 10.4 11 0 0 11 11 11 3 HEAT repeat RTP1_C1 PF10363.9 EMR61932.1 - 2.2e-07 31.1 10.9 0.00038 20.6 0.1 7.0 9 0 0 9 9 9 1 Required for nuclear transport of RNA pol II C-terminus 1 U3snoRNP10 PF12397.8 EMR61932.1 - 0.0024 18.2 1.3 0.077 13.3 0.1 3.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 Vac14_Fab1_bd PF12755.7 EMR61932.1 - 0.0036 17.8 4.5 5.6 7.6 0.0 6.6 7 1 0 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 EMR61932.1 - 0.0082 15.4 0.0 6.4 5.9 0.0 4.1 2 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Ecm29 PF13001.7 EMR61932.1 - 0.028 13.1 0.4 8.5 4.9 0.0 3.9 3 2 0 4 4 4 0 Proteasome stabiliser DUF3510 PF12022.8 EMR61932.1 - 0.051 14.0 0.7 5.4 7.4 0.0 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) Cnd1 PF12717.7 EMR61932.1 - 0.094 12.8 16.8 2.4 8.2 0.3 7.2 6 2 2 8 8 8 0 non-SMC mitotic condensation complex subunit 1 RRN3 PF05327.11 EMR61932.1 - 0.75 8.3 3.0 2.2 6.7 1.6 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 EMR61932.1 - 2.9 7.7 7.0 6.9 6.5 3.5 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region MFS_1 PF07690.16 EMR61934.1 - 2.7e-24 85.8 38.8 2.7e-24 85.8 38.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR61934.1 - 9.4e-08 31.3 13.8 9.4e-08 31.3 13.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EMR61934.1 - 3.2e-05 23.4 8.7 3.2e-05 23.4 8.7 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB IMUP PF15761.5 EMR61934.1 - 1.5 9.5 10.2 2.3 8.9 10.2 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SpoIIIAH PF12685.7 EMR61935.1 - 0.22 11.3 9.6 1.4 8.7 9.6 1.9 1 1 0 1 1 1 0 SpoIIIAH-like protein Presenilin PF01080.17 EMR61935.1 - 6.1 5.5 5.7 7.1 5.3 5.7 1.3 1 0 0 1 1 1 0 Presenilin TAF6_C PF07571.13 EMR61936.1 - 2.9e-27 94.8 0.0 9.6e-27 93.1 0.0 2.0 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EMR61936.1 - 4.9e-23 81.1 0.1 1.2e-22 79.8 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EMR61936.1 - 0.002 18.5 0.1 0.0037 17.6 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EMR61936.1 - 0.041 14.2 0.2 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EMR61936.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated CAP59_mtransfer PF11735.8 EMR61937.1 - 3.5e-67 226.6 0.0 4.2e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DBC1 PF14443.6 EMR61937.1 - 0.022 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 DBC1 EphA2_TM PF14575.6 EMR61939.1 - 0.78 10.7 0.1 0.78 10.7 0.1 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain HAT_KAT11 PF08214.11 EMR61940.1 - 4.1e-41 141.4 0.0 3.9e-29 102.0 0.1 2.1 1 1 1 2 2 2 2 Histone acetylation protein adh_short PF00106.25 EMR61941.1 - 4.9e-38 130.6 0.0 6.4e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR61941.1 - 1.6e-27 96.6 0.0 2.3e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR61941.1 - 0.00023 20.7 0.0 0.00055 19.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR61941.1 - 0.00041 20.3 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EMR61941.1 - 0.0048 16.0 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMR61941.1 - 0.011 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 EMR61941.1 - 0.082 12.4 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family DUF1776 PF08643.10 EMR61941.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF1593 PF07632.11 EMR61942.1 - 6.3e-83 278.2 0.0 9.3e-83 277.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) ABC2_membrane PF01061.24 EMR61943.1 - 3.3e-78 261.9 36.8 9.9e-41 139.5 15.0 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EMR61943.1 - 1.4e-43 148.7 0.0 1.5e-22 80.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EMR61943.1 - 9.4e-26 89.6 3.7 6.7e-23 80.4 0.1 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EMR61943.1 - 2.9e-10 39.8 7.2 2.9e-10 39.8 7.2 2.8 3 1 0 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.19 EMR61943.1 - 1.5e-07 31.1 0.3 0.19 11.1 0.0 4.3 3 3 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMR61943.1 - 4.2e-07 30.1 0.0 0.028 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMR61943.1 - 1.4e-06 28.8 0.1 0.0025 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EMR61943.1 - 2.9e-06 27.6 0.1 0.14 12.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EMR61943.1 - 7.8e-06 25.9 0.2 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EMR61943.1 - 0.00022 20.9 2.3 0.0018 17.9 0.1 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMR61943.1 - 0.00035 21.1 0.1 0.05 14.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EMR61943.1 - 0.0025 17.6 0.0 0.45 10.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMR61943.1 - 0.0043 17.3 0.1 0.022 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMR61943.1 - 0.0059 16.7 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 EMR61943.1 - 0.0085 16.0 0.3 0.38 10.6 0.1 2.8 3 0 0 3 3 3 1 NACHT domain PduV-EutP PF10662.9 EMR61943.1 - 0.012 15.4 0.1 0.44 10.3 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 EMR61943.1 - 0.021 14.0 0.1 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EMR61943.1 - 0.032 13.8 0.1 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EMR61943.1 - 0.044 14.1 0.2 4.2 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EMR61943.1 - 0.046 14.2 0.1 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EMR61943.1 - 0.071 13.5 0.1 32 5.0 0.1 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EMR61943.1 - 0.078 13.1 0.0 0.33 11.1 0.0 2.1 3 0 0 3 3 1 0 AAA domain Roc PF08477.13 EMR61943.1 - 0.085 13.1 0.2 3.3 8.0 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EMR61943.1 - 0.1 12.1 0.1 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EMR61943.1 - 0.16 12.0 0.1 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_S28e PF01200.18 EMR61943.1 - 0.17 11.9 0.0 31 4.7 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S28e Amidohydro_1 PF01979.20 EMR61944.1 - 3e-08 33.4 2.7 1.7e-07 30.9 2.7 2.0 1 1 0 1 1 1 1 Amidohydrolase family RNA_pol_3_Rpc31 PF11705.8 EMR61945.1 - 0.035 14.4 7.9 0.039 14.2 7.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1659 PF07872.11 EMR61945.1 - 0.041 13.5 0.5 0.1 12.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) Gamma-thionin PF00304.20 EMR61946.1 - 0.037 14.3 14.1 0.4 11.0 3.4 2.3 2 0 0 2 2 2 0 Gamma-thionin family ACI44 PF15270.6 EMR61946.1 - 0.34 11.1 7.6 0.19 11.9 1.4 2.2 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Colipase PF01114.18 EMR61946.1 - 0.48 10.1 16.4 0.57 9.9 5.1 2.3 2 0 0 2 2 2 0 Colipase, N-terminal domain Toxin_11 PF07473.11 EMR61946.1 - 0.66 10.1 16.2 0.75 9.9 4.1 2.6 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species NACHT_sigma PF17106.5 EMR61946.1 - 0.76 10.0 9.4 4 7.7 0.8 3.1 3 0 0 3 3 3 0 Sigma domain on NACHT-NTPases Colipase-like PF15083.6 EMR61946.1 - 2.2 8.4 5.5 8.2 6.6 0.4 2.1 2 0 0 2 2 2 0 Colipase-like DNase_NucA_NucB PF14040.6 EMR61947.1 - 8.6e-06 26.1 1.0 2.7e-05 24.5 0.6 1.9 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Acetyltransf_1 PF00583.25 EMR61948.1 - 5.4e-18 65.3 0.0 7.6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR61948.1 - 1.1e-13 51.2 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR61948.1 - 8.4e-11 42.2 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR61948.1 - 2.6e-09 36.9 0.0 3e-08 33.5 0.0 2.4 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_3 PF13302.7 EMR61948.1 - 5.3e-08 33.6 0.0 6.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMR61948.1 - 2e-05 24.8 0.0 3.3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR61948.1 - 0.00013 22.0 0.1 0.0004 20.5 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EMR61948.1 - 0.063 13.3 0.1 4.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EMR61948.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 2 0 0 2 2 2 0 GNAT acetyltransferase FMN_bind_2 PF04299.12 EMR61949.1 - 4.1e-57 192.5 0.0 4.8e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain GMC_oxred_C PF05199.13 EMR61950.1 - 2.5e-38 131.8 0.1 4.1e-38 131.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR61950.1 - 5.2e-37 127.8 0.0 4.7e-31 108.3 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 EMR61950.1 - 9.9e-07 28.3 0.0 0.033 13.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR61950.1 - 2.4e-06 27.4 0.1 5.2e-06 26.3 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR61950.1 - 4.2e-05 23.7 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR61950.1 - 0.0011 18.1 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMR61950.1 - 0.0049 16.9 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EMR61950.1 - 0.0075 15.4 1.8 0.13 11.4 1.8 2.2 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EMR61950.1 - 0.0092 15.1 0.4 0.39 9.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Ribonucleas_3_3 PF14622.6 EMR61952.1 - 1.2e-26 93.4 0.0 2e-26 92.6 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Glyco_hydro_61 PF03443.14 EMR61956.1 - 2.8e-54 184.2 0.0 3.4e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Beta_elim_lyase PF01212.21 EMR61957.1 - 5.9e-52 176.8 0.0 6.8e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMR61957.1 - 1.3e-05 24.7 0.1 1.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EMR61957.1 - 0.00048 19.4 0.0 0.00063 19.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMR61957.1 - 0.00085 18.0 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMR61957.1 - 0.023 13.7 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V OKR_DC_1 PF01276.20 EMR61957.1 - 0.092 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain TRI12 PF06609.13 EMR61958.1 - 4.7e-38 131.0 34.1 7.9e-16 57.6 5.8 3.0 1 1 1 3 3 3 3 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EMR61958.1 - 1.6e-11 43.7 43.7 1.6e-11 43.7 43.7 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_92 PF07971.12 EMR61961.1 - 4.1e-129 431.5 3.2 5.4e-129 431.1 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMR61961.1 - 1.9e-50 172.0 4.1 3.3e-50 171.2 4.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Bac_rhodopsin PF01036.18 EMR61963.1 - 7.5e-58 195.7 13.4 9.9e-58 195.3 13.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Rx_N PF18052.1 EMR61964.1 - 0.028 14.7 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Rx N-terminal domain Methyltransf_23 PF13489.6 EMR61965.1 - 7.6e-19 68.1 0.0 9.6e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR61965.1 - 2.9e-13 50.3 0.0 7.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR61965.1 - 3.2e-13 50.2 0.0 1.1e-12 48.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR61965.1 - 1e-11 44.9 0.0 9.3e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EMR61965.1 - 2.3e-10 41.1 0.0 1.8e-09 38.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR61965.1 - 3.4e-07 29.8 0.0 3.9e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EMR61965.1 - 0.024 14.5 0.0 0.18 11.6 0.0 2.3 2 1 0 2 2 2 0 Hypothetical methyltransferase CMAS PF02353.20 EMR61965.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 EMR61965.1 - 0.061 11.9 0.1 0.58 8.6 0.1 2.0 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase UPF0146 PF03686.13 EMR61965.1 - 0.14 12.1 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) MTS PF05175.14 EMR61965.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Diphthamide_syn PF01866.17 EMR61966.1 - 1.9e-78 264.0 0.0 8.2e-78 261.9 0.0 1.8 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Transferase PF02458.15 EMR61967.1 - 1.9e-07 30.1 0.0 3.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Transferase family DUF758 PF05527.11 EMR61968.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF758) PAF-AH_p_II PF03403.13 EMR61969.1 - 7.8e-27 93.8 0.0 1.1e-25 90.0 0.0 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EMR61969.1 - 2.7e-11 42.9 0.0 3.3e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 EMR61969.1 - 2.4e-06 26.8 0.1 0.0024 17.0 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Hydrolase_4 PF12146.8 EMR61969.1 - 0.00027 20.3 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMR61969.1 - 0.18 11.3 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4136 PF13590.6 EMR61970.1 - 0.023 15.2 0.0 0.034 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) AAA PF00004.29 EMR61971.1 - 1.8e-18 67.3 0.0 9.1e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR61971.1 - 0.014 15.8 0.1 0.049 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 EMR61971.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR61971.1 - 0.042 14.1 0.3 1.2 9.4 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 EMR61971.1 - 0.063 13.8 0.0 0.56 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EMR61971.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EMR61971.1 - 0.12 11.6 0.2 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MFS_1 PF07690.16 EMR61972.1 - 6.2e-19 68.1 31.7 2.4e-18 66.2 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1799 PF08809.11 EMR61972.1 - 0.11 12.8 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) AAA_16 PF13191.6 EMR61973.1 - 5.7e-06 26.8 0.0 8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR61973.1 - 8.1e-05 22.9 0.0 0.00021 21.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EMR61973.1 - 0.00023 21.6 0.0 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 EMR61973.1 - 0.0085 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EMR61973.1 - 0.015 15.9 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMR61973.1 - 0.016 15.2 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EMR61973.1 - 0.024 13.9 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 EMR61973.1 - 0.032 13.2 0.3 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EMR61973.1 - 0.032 14.7 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 EMR61973.1 - 0.058 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Torsin PF06309.11 EMR61973.1 - 0.062 13.4 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Torsin SRP54 PF00448.22 EMR61973.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EMR61973.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMR61973.1 - 0.078 13.1 0.2 0.22 11.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EMR61973.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PAM2 PF07145.15 EMR61975.1 - 0.0011 18.4 0.3 0.039 13.6 0.1 2.4 2 0 0 2 2 2 2 Ataxin-2 C-terminal region MFS_1 PF07690.16 EMR61976.1 - 2e-30 105.9 30.1 9.4e-29 100.4 14.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 EMR61976.1 - 0.44 8.8 8.6 0.041 12.2 2.8 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MMPL PF03176.15 EMR61976.1 - 0.53 9.1 4.5 0.16 10.8 0.8 2.0 2 0 0 2 2 2 0 MMPL family DUF87 PF01935.17 EMR61977.1 - 5.3e-05 23.4 0.0 0.00098 19.3 0.0 2.2 1 1 0 1 1 1 1 Helicase HerA, central domain ATPase_2 PF01637.18 EMR61977.1 - 0.035 14.0 0.0 8.4 6.2 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 EMR61977.1 - 0.045 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 EMR61977.1 - 0.05 13.9 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMR61977.1 - 0.072 13.5 0.0 0.65 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 EMR61978.1 - 2.6e-41 141.7 0.0 3.2e-40 138.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR61978.1 - 1.3e-29 103.3 0.0 2e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.22 EMR61978.1 - 2.1e-15 56.8 10.2 3.9e-15 55.9 10.2 1.3 1 0 0 1 1 1 1 Subtilase family Kdo PF06293.14 EMR61978.1 - 0.0025 17.2 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Flavi_propep PF01570.17 EMR61978.1 - 0.14 12.2 0.0 0.87 9.6 0.0 2.1 2 0 0 2 2 2 0 Flavivirus polyprotein propeptide Pkinase PF00069.25 EMR61979.1 - 2.1e-24 86.3 0.0 6.7e-18 65.0 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR61979.1 - 1.2e-06 28.1 0.0 0.0085 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EMR61979.1 - 0.0081 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EMR61979.1 - 0.028 13.8 0.0 0.069 12.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPE65 PF03055.15 EMR61981.1 - 2.5e-98 330.3 0.0 5.2e-54 184.2 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein PAD PF03068.15 EMR61982.1 - 9.1e-130 433.1 0.0 1.1e-129 432.8 0.0 1.0 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Cas_Cas02710 PF09670.10 EMR61982.1 - 0.22 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Ank_5 PF13857.6 EMR61983.1 - 8e-05 22.9 0.3 0.0016 18.7 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR61983.1 - 0.0016 18.9 0.1 0.025 15.1 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR61983.1 - 0.066 13.8 0.4 0.85 10.4 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat PSDC PF12588.8 EMR61984.1 - 1.3e-52 177.5 0.0 2.1e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EMR61984.1 - 6.2e-32 110.8 0.0 8.7e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_S8 PF00082.22 EMR61985.1 - 2e-09 37.2 0.0 3.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Exonuc_VII_L PF02601.15 EMR61985.1 - 0.024 14.2 0.5 0.05 13.2 0.5 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Glyco_hydro_61 PF03443.14 EMR61986.1 - 1.2e-46 159.2 0.0 1.4e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NACHT PF05729.12 EMR61987.1 - 8.7e-14 51.8 0.0 1.5e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 EMR61987.1 - 5.6e-10 38.9 0.1 1.4e-09 37.5 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily AAA PF00004.29 EMR61987.1 - 2.9e-05 24.5 0.0 0.0001 22.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EMR61987.1 - 0.00012 22.1 0.0 0.0056 16.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMR61987.1 - 0.00022 21.5 0.0 0.0015 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EMR61987.1 - 0.00034 20.6 0.0 0.58 10.0 0.0 3.0 4 0 0 4 4 4 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EMR61987.1 - 0.00084 19.8 0.0 0.0033 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EMR61987.1 - 0.0023 17.2 0.0 0.0059 15.8 0.0 1.8 1 1 1 2 2 2 1 NB-ARC domain RNA_helicase PF00910.22 EMR61987.1 - 0.01 16.2 0.2 0.045 14.1 0.1 2.3 2 1 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 EMR61987.1 - 0.017 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EMR61987.1 - 0.1 11.9 0.2 0.57 9.5 0.0 2.3 2 1 0 2 2 2 0 KaiC AAA_33 PF13671.6 EMR61987.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF4508 PF14969.6 EMR61987.1 - 0.13 12.5 0.2 0.37 11.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) PIG-S PF10510.9 EMR61988.1 - 4.7e-129 431.5 2.2 6.2e-129 431.1 2.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein AF-4 PF05110.13 EMR61988.1 - 5.8 4.9 12.3 11 4.0 12.3 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AMP-binding PF00501.28 EMR61989.1 - 4.8e-67 226.4 0.0 6.4e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR61989.1 - 8.7e-09 36.2 0.4 2.2e-08 35.0 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NmrA PF05368.13 EMR61990.1 - 4.7e-24 85.2 4.7 6.1e-24 84.9 4.7 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR61990.1 - 4.3e-20 72.4 0.9 6.4e-20 71.8 0.9 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMR61990.1 - 2.3e-08 34.3 1.6 6.6e-08 32.9 0.4 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EMR61990.1 - 7.6e-07 28.8 0.1 1.6e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMR61990.1 - 1.8e-05 24.3 0.8 3.5e-05 23.3 0.8 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 EMR61990.1 - 2e-05 24.7 0.4 4.4e-05 23.6 0.4 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EMR61990.1 - 9.3e-05 22.8 1.1 0.00018 21.9 1.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding 3Beta_HSD PF01073.19 EMR61990.1 - 0.0013 17.8 0.2 0.0032 16.5 0.2 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMR61990.1 - 0.0059 16.0 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EMR61990.1 - 0.0067 17.0 0.6 0.018 15.6 0.6 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 EMR61990.1 - 0.0073 15.6 1.6 0.021 14.2 0.8 2.2 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 EMR61990.1 - 0.012 15.6 0.5 0.027 14.4 0.5 1.6 1 1 0 1 1 1 0 KR domain NAD_binding_2 PF03446.15 EMR61990.1 - 0.012 15.8 0.5 0.023 14.9 0.2 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 EMR61990.1 - 0.021 15.1 1.3 0.03 14.6 0.5 1.7 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 EMR61990.1 - 0.12 12.9 1.3 0.32 11.6 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LisH_2 PF16045.5 EMR61991.1 - 0.027 13.5 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 LisH Polysacc_synt_4 PF04669.13 EMR61992.1 - 5.6e-21 75.0 0.9 5.1e-19 68.6 0.9 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 EMR61992.1 - 0.061 13.0 1.0 0.13 12.0 1.0 1.6 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Amidoligase_2 PF12224.8 EMR61993.1 - 2.5e-15 56.8 0.0 1.2e-13 51.3 0.0 2.5 2 1 0 2 2 2 2 Putative amidoligase enzyme Ribosomal_L37e PF01907.19 EMR61993.1 - 0.14 12.3 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e p450 PF00067.22 EMR61994.1 - 1.8e-48 165.5 0.0 4.4e-48 164.2 0.0 1.5 1 1 1 2 2 2 1 Cytochrome P450 NUP PF06516.11 EMR61995.1 - 1.8e-125 418.3 0.0 2.1e-125 418.1 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Kelch_1 PF01344.25 EMR61996.1 - 2.7e-41 138.9 18.3 3.6e-10 39.3 0.1 7.0 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EMR61996.1 - 5.5e-27 93.1 12.8 1.1e-06 28.6 0.1 7.2 3 2 3 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EMR61996.1 - 1.1e-20 73.3 14.3 0.0012 18.8 0.1 6.3 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EMR61996.1 - 3.7e-20 71.7 10.5 5.6e-06 26.5 0.3 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EMR61996.1 - 9.6e-13 47.6 15.8 0.032 14.2 0.0 7.1 6 3 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EMR61996.1 - 1e-09 38.2 10.1 1.4 9.0 0.6 6.5 6 1 0 6 6 6 4 Kelch motif DNA_pol_P_Exo PF18049.1 EMR61996.1 - 0.085 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo PQQ_3 PF13570.6 EMR61996.1 - 2.5 8.7 19.1 0.097 13.2 1.0 4.8 5 1 0 5 5 5 0 PQQ-like domain 7TMR-DISM_7TM PF07695.11 EMR61997.1 - 0.03 14.2 8.7 0.14 12.1 4.3 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF1129 PF06570.11 EMR61997.1 - 4.5 6.7 5.6 0.93 8.9 1.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) ABC_membrane PF00664.23 EMR61999.1 - 9.1e-61 205.9 17.9 1.6e-35 123.1 13.0 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EMR61999.1 - 1.4e-54 184.3 0.0 7e-26 91.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMR61999.1 - 4e-13 49.3 0.1 1.7e-06 27.7 0.0 5.0 5 1 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMR61999.1 - 4.8e-10 39.7 2.0 0.017 15.0 0.0 3.7 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMR61999.1 - 3.4e-09 37.1 0.0 0.0016 18.7 0.0 3.5 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EMR61999.1 - 9.4e-08 32.1 0.4 0.0029 17.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EMR61999.1 - 3.8e-07 29.7 4.6 0.0014 18.4 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EMR61999.1 - 3.3e-06 27.6 0.3 0.13 12.6 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EMR61999.1 - 0.00014 21.8 0.2 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EMR61999.1 - 0.00026 21.0 0.7 0.33 11.1 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EMR61999.1 - 0.00031 21.3 0.0 0.38 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMR61999.1 - 0.00032 21.3 0.5 0.045 14.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 EMR61999.1 - 0.00047 19.1 0.1 2.9 6.6 0.0 4.3 5 0 0 5 5 5 1 Predicted ATPase of the ABC class RNA_helicase PF00910.22 EMR61999.1 - 0.00064 20.1 0.2 1.6 9.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 EMR61999.1 - 0.00077 19.1 1.0 0.81 9.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EMR61999.1 - 0.0012 19.0 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EMR61999.1 - 0.0016 18.4 0.0 2.7 8.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EMR61999.1 - 0.012 15.1 0.1 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EMR61999.1 - 0.017 14.4 0.0 0.57 9.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.16 EMR61999.1 - 0.035 13.4 0.2 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family AAA_30 PF13604.6 EMR61999.1 - 0.037 13.8 0.2 12 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EMR61999.1 - 0.042 13.9 0.0 13 5.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 EMR61999.1 - 0.049 13.5 0.3 15 5.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Septin PF00735.18 EMR61999.1 - 0.05 12.9 0.0 8.4 5.6 0.0 2.3 2 0 0 2 2 2 0 Septin DUF87 PF01935.17 EMR61999.1 - 0.077 13.1 2.2 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 EMR61999.1 - 0.11 12.2 0.3 5.6 6.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EMR61999.1 - 0.12 12.3 0.2 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 EMR61999.1 - 0.18 11.7 0.2 13 5.7 0.0 2.8 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EMR61999.1 - 0.19 11.1 0.2 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TPR_15 PF13429.6 EMR62000.1 - 0.18 11.0 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF463 PF04317.12 EMR62000.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 COG5 PF10392.9 EMR62001.1 - 6.3e-38 129.9 3.0 8.4e-38 129.5 0.3 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF1722 PF08349.11 EMR62001.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) LPP PF04728.13 EMR62001.1 - 0.99 9.8 3.7 1.5 9.3 2.1 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper adh_short PF00106.25 EMR62002.1 - 4.3e-24 85.0 0.2 4.3e-21 75.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62002.1 - 6.8e-16 58.5 0.1 4.4e-14 52.6 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62002.1 - 3.6e-11 43.3 0.1 6.7e-11 42.4 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR62002.1 - 0.0029 17.1 0.1 0.0064 16.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rad17 PF03215.15 EMR62002.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain tRNA-synt_1 PF00133.22 EMR62003.1 - 1.2e-39 136.0 0.0 1.2e-26 93.2 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EMR62003.1 - 1.4e-16 60.3 0.0 2e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EMR62003.1 - 1.6e-13 50.9 0.1 3.3e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EMR62003.1 - 8.8e-09 35.1 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Chlorosome_CsmC PF11098.8 EMR62004.1 - 0.013 15.5 9.5 0.018 15.0 9.5 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C VPS13_C PF16909.5 EMR62004.1 - 7.4 6.3 6.1 15 5.3 5.8 1.6 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Epimerase PF01370.21 EMR62005.1 - 1.8e-12 47.2 0.0 6.2e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR62005.1 - 0.00077 18.9 0.0 0.0032 16.9 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMR62005.1 - 0.0023 17.4 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EMR62005.1 - 0.0038 16.8 0.0 0.021 14.4 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EMR62005.1 - 0.028 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 EMR62005.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_transf_20 PF00982.21 EMR62006.1 - 2.4e-148 494.8 0.0 3.7e-148 494.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EMR62006.1 - 1.2e-73 247.1 0.4 2.6e-73 246.0 0.1 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EMR62006.1 - 0.0002 21.2 0.0 0.11 12.2 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Porin_O_P PF07396.11 EMR62006.1 - 0.069 12.3 0.0 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 Phosphate-selective porin O and P MFS_1 PF07690.16 EMR62007.1 - 1.4e-12 47.3 9.1 5.6e-09 35.4 7.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR62007.1 - 0.00015 20.7 1.5 0.00018 20.5 1.5 1.2 1 0 0 1 1 1 1 MFS_1 like family FtsX PF02687.21 EMR62007.1 - 0.092 13.2 0.8 0.092 13.2 0.8 2.7 2 2 0 2 2 2 0 FtsX-like permease family DUF3792 PF12670.7 EMR62007.1 - 0.59 10.3 8.4 9.9 6.4 4.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) Paramyx_P_V_C PF03210.13 EMR62008.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Oxidored_FMN PF00724.20 EMR62010.1 - 2.3e-60 204.7 0.0 1.5e-59 202.0 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Clat_adaptor_s PF01217.20 EMR62011.1 - 1.7e-56 190.1 2.1 1.9e-56 189.9 2.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LCM PF04072.14 EMR62012.1 - 1.4e-21 77.3 0.0 3.1e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Lipase_GDSL_2 PF13472.6 EMR62012.1 - 1.4e-14 54.9 0.2 4.1e-14 53.4 0.1 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR62012.1 - 5.4e-06 26.5 0.1 2.3e-05 24.5 0.0 2.1 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 EMR62012.1 - 0.00041 19.7 0.0 0.00062 19.1 0.0 1.2 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_3 PF14606.6 EMR62012.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FoP_duplication PF13865.6 EMR62012.1 - 4.6 7.9 6.8 13 6.4 6.8 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Zn_clus PF00172.18 EMR62013.1 - 0.00014 21.9 11.7 0.00028 21.0 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR62013.1 - 0.003 16.6 0.0 0.25 10.3 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Cdd1 PF11731.8 EMR62013.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus ArAE_2 PF10334.9 EMR62014.1 - 6.7e-06 26.1 0.0 9.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EMR62014.1 - 0.02 13.8 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Fructosamin_kin PF03881.14 EMR62015.1 - 2.4e-25 89.3 0.0 3e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EMR62015.1 - 0.028 14.3 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family GMC_oxred_N PF00732.19 EMR62016.1 - 1.6e-23 83.5 0.0 1.2e-16 60.9 0.0 3.1 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR62016.1 - 5.4e-23 82.1 0.0 8.7e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EMR62016.1 - 2.6e-06 27.6 0.1 5.6e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR62016.1 - 0.00048 19.5 0.0 0.00075 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EMR62016.1 - 0.00091 18.9 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 EMR62016.1 - 0.0047 16.1 1.0 0.0069 15.5 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EMR62016.1 - 0.01 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EMR62016.1 - 0.012 14.3 0.2 0.018 13.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 EMR62016.1 - 0.059 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMR62016.1 - 0.11 11.7 0.2 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EMR62016.1 - 0.13 11.5 0.0 3.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EKR PF10371.9 EMR62016.1 - 0.17 11.7 0.1 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function GIDA PF01134.22 EMR62016.1 - 0.27 10.3 0.0 0.41 9.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TFIID-18kDa PF02269.16 EMR62017.1 - 4.3e-29 100.4 1.3 3.8e-28 97.3 0.2 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.18 EMR62017.1 - 0.03 14.2 0.7 0.048 13.6 0.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Ist1 PF03398.14 EMR62019.1 - 5.6e-60 202.0 0.8 7.2e-60 201.6 0.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Pkinase PF00069.25 EMR62020.1 - 9.9e-13 48.1 0.0 3.2e-07 30.0 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain APH PF01636.23 EMR62020.1 - 0.00063 19.7 0.0 0.015 15.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EMR62020.1 - 0.00075 18.9 0.0 0.024 13.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase DUF5570 PF17731.1 EMR62020.1 - 0.058 13.5 0.2 5.5 7.1 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5570) Kdo PF06293.14 EMR62020.1 - 0.078 12.3 0.1 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spc7 PF08317.11 EMR62020.1 - 0.19 10.5 0.9 0.29 10.0 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein EB1 PF03271.17 EMR62021.1 - 4.5e-17 62.0 1.4 8.3e-17 61.2 1.4 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EMR62021.1 - 8.8e-06 25.9 0.6 1.5e-05 25.1 0.6 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain LMSTEN PF07988.12 EMR62021.1 - 0.16 11.5 1.3 0.57 9.7 0.7 2.1 2 0 0 2 2 2 0 LMSTEN motif Tyrosinase PF00264.20 EMR62022.1 - 3.9e-38 132.0 0.0 4.8e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase TPR_12 PF13424.6 EMR62023.1 - 1.3e-16 60.7 12.7 0.011 16.0 0.3 9.1 10 1 0 10 10 10 4 Tetratricopeptide repeat NACHT PF05729.12 EMR62023.1 - 7.8e-09 35.7 0.7 3.4e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EMR62023.1 - 1.1e-06 29.1 0.0 3.8e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR62023.1 - 3.6e-05 24.0 1.0 0.00018 21.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_10 PF13374.6 EMR62023.1 - 0.0023 17.7 3.7 8.4 6.4 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR62023.1 - 0.0059 16.6 8.6 2.2 8.6 0.6 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat AAA PF00004.29 EMR62023.1 - 0.013 16.0 0.1 0.069 13.6 0.0 2.4 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EMR62023.1 - 0.05 13.8 0.5 0.37 11.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain DUF1798 PF08807.10 EMR62023.1 - 0.073 13.2 2.8 1.4 9.1 0.2 3.8 4 0 0 4 4 4 0 Bacterial domain of unknown function (DUF1798) TPR_16 PF13432.6 EMR62023.1 - 0.08 13.6 0.2 19 6.0 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat CENP-X PF09415.10 EMR62023.1 - 0.11 12.9 0.1 0.57 10.5 0.1 2.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TPR_19 PF14559.6 EMR62023.1 - 0.11 13.0 2.0 0.87 10.1 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMR62023.1 - 0.21 11.7 9.0 3.4 7.9 0.0 6.0 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF1947 PF09183.10 EMR62023.1 - 0.78 10.1 5.5 0.14 12.4 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) TPR_1 PF00515.28 EMR62023.1 - 1.4 8.9 8.4 2.6 8.0 0.6 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMR62023.1 - 1.7 9.0 17.7 15 6.1 0.4 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR62023.1 - 4.4 7.6 20.1 0.21 11.9 0.5 5.8 6 1 1 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Acetyltransf_3 PF13302.7 EMR62024.1 - 3.1e-15 57.0 0.0 4.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR62024.1 - 3.1e-05 24.2 0.0 4.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family D123 PF07065.14 EMR62025.1 - 0.0065 15.7 0.0 0.023 13.9 0.0 1.7 1 1 0 1 1 1 1 D123 DnaJ PF00226.31 EMR62027.1 - 2.2e-15 56.5 0.1 1.4e-14 53.9 0.1 2.2 1 1 0 1 1 1 1 DnaJ domain RPT PF13446.6 EMR62027.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein Vfa1 PF08432.10 EMR62027.1 - 0.29 11.4 10.8 0.1 12.9 8.2 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UcrQ PF02939.16 EMR62028.1 - 1.8e-35 120.7 0.5 2.2e-35 120.4 0.5 1.1 1 0 0 1 1 1 1 UcrQ family Herpes_BMRF2 PF04633.12 EMR62028.1 - 0.043 13.1 0.0 0.047 12.9 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein RGS PF00615.19 EMR62029.1 - 0.00012 22.3 0.1 0.00037 20.7 0.1 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain Mdv1 PF11542.8 EMR62029.1 - 0.0095 15.9 0.1 0.033 14.2 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial division protein 1 MFS_3 PF05977.13 EMR62029.1 - 0.014 13.8 0.0 0.021 13.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector DUF4559 PF15112.6 EMR62030.1 - 0.044 13.5 1.6 0.056 13.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) BLI1 PF17324.2 EMR62030.1 - 0.15 12.7 3.4 0.28 11.9 3.4 1.4 1 0 0 1 1 1 0 BLOC-1 interactor 1 DUF3327 PF11806.8 EMR62030.1 - 1.1 10.0 3.8 2.3 9.0 0.1 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3327) DUF745 PF05335.13 EMR62030.1 - 2.9 7.6 8.2 0.93 9.2 2.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF1635 PF07795.11 EMR62030.1 - 4 7.2 7.6 12 5.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) UPF0242 PF06785.11 EMR62030.1 - 8.1 6.5 8.6 5.4 7.1 6.4 1.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus p450 PF00067.22 EMR62031.1 - 3.7e-45 154.5 0.0 4.6e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 REC1 PF18501.1 EMR62031.1 - 0.19 11.6 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Alpha helical recognition lobe domain DUF2415 PF10313.9 EMR62032.1 - 0.00011 22.1 0.1 0.012 15.5 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 EMR62032.1 - 0.0054 17.0 0.1 1.4 9.2 0.0 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMR62032.1 - 0.0078 17.1 0.4 0.04 14.8 0.2 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EMR62032.1 - 0.01 14.4 0.0 0.069 11.7 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain Chitin_synth_2 PF03142.15 EMR62033.1 - 1.9e-287 954.1 0.1 2.4e-287 953.7 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EMR62033.1 - 8.9e-13 48.6 7.5 2.8e-12 46.9 6.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMR62033.1 - 6.4e-10 39.3 0.0 9.3e-09 35.5 0.0 2.5 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMR62033.1 - 0.0024 17.4 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 DASH_Dad4 PF08650.10 EMR62034.1 - 9.7e-30 102.4 9.2 1.2e-29 102.1 9.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 Got1 PF04178.12 EMR62035.1 - 1.4e-15 57.7 10.9 1.7e-15 57.4 10.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Profilin PF00235.19 EMR62036.1 - 1.9e-49 167.2 1.7 2.1e-49 167.0 1.7 1.0 1 0 0 1 1 1 1 Profilin DUF2544 PF11245.8 EMR62036.1 - 0.052 13.0 0.0 0.088 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2544) DUF4874 PF16173.5 EMR62036.1 - 0.15 11.7 0.1 0.55 9.9 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4874) Macoilin PF09726.9 EMR62037.1 - 9.3 4.7 9.2 9.8 4.6 9.2 1.1 1 0 0 1 1 1 0 Macoilin family Actin PF00022.19 EMR62038.1 - 1.2e-30 106.5 0.0 2.6e-30 105.4 0.0 1.5 1 1 0 1 1 1 1 Actin SMBP PF16785.5 EMR62038.1 - 0.087 13.1 0.5 0.18 12.0 0.5 1.5 1 0 0 1 1 1 0 Small metal-binding protein YL1_C PF08265.11 EMR62039.1 - 1.4e-14 53.5 0.2 2.2e-14 52.9 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF2967 PF11179.8 EMR62039.1 - 0.036 12.2 4.8 0.019 13.1 3.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2967) DUF1751 PF08551.10 EMR62040.1 - 6e-29 100.5 4.1 1.4e-28 99.3 4.1 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EMR62040.1 - 0.026 14.5 8.7 0.047 13.7 8.7 1.4 1 0 0 1 1 1 0 Rhomboid family TUG-UBL1 PF11470.8 EMR62043.1 - 6.2e-25 87.2 0.2 1.3e-24 86.2 0.2 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 EMR62043.1 - 0.00021 21.4 0.0 0.00071 19.7 0.0 1.9 2 0 0 2 2 2 1 UBX domain Rad60-SLD PF11976.8 EMR62043.1 - 0.003 17.4 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4294 PF14127.6 EMR62043.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) ubiquitin PF00240.23 EMR62043.1 - 0.16 11.8 0.3 0.29 10.9 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin family AMP-binding PF00501.28 EMR62044.1 - 4.1e-93 312.3 0.0 4.9e-93 312.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR62044.1 - 4.4e-13 50.0 0.1 9.3e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 EMR62045.1 - 9.2e-67 225.2 0.0 1.3e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR62045.1 - 6.4e-42 143.6 0.0 9.3e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR62045.1 - 6.7e-07 28.9 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.18 EMR62045.1 - 1.2e-06 28.6 0.1 0.0015 18.7 0.0 3.0 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.14 EMR62045.1 - 0.0024 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMR62045.1 - 0.013 14.5 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EMR62045.1 - 0.032 13.0 0.4 0.058 12.2 0.4 1.3 1 0 0 1 1 1 0 Fungal protein kinase Suf PF05843.14 EMR62046.1 - 9.9e-08 32.3 6.9 0.00015 21.9 0.6 3.4 2 1 1 3 3 3 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EMR62046.1 - 1.3e-07 31.8 3.1 0.069 14.0 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EMR62046.1 - 8.8 6.6 6.3 38 4.6 0.4 3.7 3 1 0 3 3 3 0 c-SKI Smad4 binding domain Glyco_hydro_17 PF00332.18 EMR62047.1 - 2.3e-05 24.1 0.0 4.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 RNB PF00773.19 EMR62048.1 - 1.7e-55 188.6 0.0 4.5e-55 187.3 0.0 1.7 1 1 0 1 1 1 1 RNB domain Ras PF00071.22 EMR62049.1 - 2.6e-49 166.9 0.0 3.2e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR62049.1 - 7.4e-30 103.6 0.1 1.9e-29 102.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR62049.1 - 7.5e-11 41.8 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMR62049.1 - 0.00028 20.9 0.0 0.00064 19.8 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EMR62049.1 - 0.00042 20.7 0.2 0.0037 17.6 0.2 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EMR62049.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EMR62049.1 - 0.017 14.3 1.8 1 8.5 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 EMR62049.1 - 0.019 14.4 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 EMR62049.1 - 0.022 14.7 0.1 7.1 6.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EMR62049.1 - 0.025 14.1 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EMR62049.1 - 0.066 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EMR62049.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 EMR62049.1 - 0.084 12.9 0.1 0.19 11.8 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EMR62049.1 - 0.099 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR62049.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EMR62049.1 - 0.17 11.2 0.5 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Septin Proteasome PF00227.26 EMR62050.1 - 2.1e-41 141.5 0.0 2.4e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit AAA PF00004.29 EMR62051.1 - 1.2e-45 155.1 0.0 1.9e-43 148.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR62051.1 - 2.7e-05 24.6 1.1 0.0075 16.7 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 EMR62051.1 - 4.7e-05 23.1 2.2 0.024 14.4 0.1 3.3 3 0 0 3 3 3 1 AAA+ lid domain RuvB_N PF05496.12 EMR62051.1 - 6.1e-05 22.8 0.0 0.00017 21.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EMR62051.1 - 0.00026 20.2 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 EMR62051.1 - 0.00079 19.6 0.0 0.0028 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EMR62051.1 - 0.0013 18.2 1.0 0.021 14.2 0.0 2.9 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EMR62051.1 - 0.0013 19.0 0.0 0.015 15.6 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.6 EMR62051.1 - 0.0014 18.2 0.0 0.0086 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMR62051.1 - 0.0027 17.5 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EMR62051.1 - 0.0034 17.7 0.0 0.013 15.9 0.0 2.1 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EMR62051.1 - 0.0044 16.3 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EMR62051.1 - 0.0096 15.9 0.0 0.048 13.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 EMR62051.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.5 2 0 0 2 2 1 0 KaiC AAA_7 PF12775.7 EMR62051.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EMR62051.1 - 0.022 15.3 0.0 0.055 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMR62051.1 - 0.023 15.0 0.1 0.087 13.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 EMR62051.1 - 0.027 14.6 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EMR62051.1 - 0.032 13.7 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 EMR62051.1 - 0.039 13.9 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EMR62051.1 - 0.042 13.0 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 EMR62051.1 - 0.065 13.7 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EMR62051.1 - 0.078 12.2 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 EMR62051.1 - 0.081 12.6 1.5 0.4 10.4 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 EMR62051.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 EMR62051.1 - 0.12 12.4 0.0 2.8 8.0 0.0 2.9 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain PPV_E1_C PF00519.17 EMR62051.1 - 0.18 10.6 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Spt20 PF12090.8 EMR62051.1 - 0.26 10.9 6.3 0.5 9.9 6.3 1.4 1 0 0 1 1 1 0 Spt20 family Sel1 PF08238.12 EMR62052.1 - 3e-40 135.7 31.5 2.7e-07 31.0 0.6 7.3 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EMR62052.1 - 0.018 15.6 4.2 0.47 11.2 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat SBDS PF01172.18 EMR62053.1 - 6.3e-25 87.1 0.6 7.5e-25 86.8 0.6 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ATP11 PF06644.11 EMR62054.1 - 1.6e-90 303.6 0.0 1.8e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Roughex PF06020.11 EMR62054.1 - 0.12 11.5 0.6 0.17 11.0 0.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein peroxidase PF00141.23 EMR62055.1 - 3.1e-46 157.9 0.0 5.6e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Peroxidase AIF-MLS PF14962.6 EMR62055.1 - 0.032 14.2 0.5 0.044 13.7 0.5 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence E1-E2_ATPase PF00122.20 EMR62057.1 - 1.3e-48 164.9 4.7 2.5e-48 164.0 1.4 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMR62057.1 - 2.4e-47 161.0 4.1 4.5e-47 160.1 4.1 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMR62057.1 - 1.3e-23 84.4 0.7 1.7e-22 80.8 0.7 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMR62057.1 - 9.4e-21 73.7 0.0 1.8e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMR62057.1 - 6e-18 64.3 0.0 1.5e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMR62057.1 - 4.4e-09 36.4 1.4 9.2e-07 28.9 1.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMR62057.1 - 4.1e-05 24.1 0.0 0.00016 22.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase OPA3 PF07047.12 EMR62058.1 - 8.8e-44 148.3 0.9 1.2e-43 147.9 0.9 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HAUS6_N PF14661.6 EMR62058.1 - 0.015 14.9 3.6 0.086 12.4 0.4 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus JAKMIP_CC3 PF16034.5 EMR62058.1 - 0.017 15.1 5.4 0.021 14.7 0.7 2.1 2 0 0 2 2 2 0 JAKMIP CC3 domain FemAB PF02388.16 EMR62058.1 - 0.27 10.0 4.3 0.53 9.1 0.2 2.0 2 0 0 2 2 2 0 FemAB family DUF4140 PF13600.6 EMR62058.1 - 6.9 7.2 8.5 1.7 9.1 0.9 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3552 PF12072.8 EMR62058.1 - 7.1 6.0 14.6 2.5 7.5 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4200 PF13863.6 EMR62058.1 - 9.4 6.7 14.5 1.6 9.2 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Syja_N PF02383.18 EMR62059.1 - 2.1e-57 194.8 0.0 3.3e-51 174.5 0.0 2.7 1 1 1 2 2 2 2 SacI homology domain Exo_endo_phos PF03372.23 EMR62059.1 - 5.7e-05 22.7 0.0 9.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TFIIA PF03153.13 EMR62060.1 - 0.0036 17.4 38.6 0.0046 17.0 38.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SH3BGR PF04908.15 EMR62060.1 - 0.0038 17.3 0.0 0.0038 17.3 0.0 3.0 3 1 0 3 3 3 1 SH3-binding, glutamic acid-rich protein 14-3-3 PF00244.20 EMR62061.1 - 6.4e-107 356.1 1.7 7.8e-107 355.8 1.7 1.1 1 0 0 1 1 1 1 14-3-3 protein Ribosomal_L36e PF01158.18 EMR62062.1 - 9.4e-40 134.8 5.4 1.1e-39 134.6 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e INT_SG_DDX_CT_C PF15300.6 EMR62062.1 - 0.051 13.4 0.4 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus INO80_Ies4 PF08193.11 EMR62063.1 - 9.3 6.2 8.5 13 5.6 8.5 1.4 1 1 0 1 1 1 0 INO80 complex subunit Ies4 Nas2_N PF18265.1 EMR62064.1 - 8.9e-31 105.7 0.1 1.3e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EMR62064.1 - 1.4e-05 24.9 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EMR62064.1 - 0.00017 21.9 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EMR62064.1 - 0.0013 19.0 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain MAD PF05557.13 EMR62064.1 - 0.086 11.2 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ELO PF01151.18 EMR62065.1 - 1.8e-77 260.3 8.6 2.1e-77 260.0 8.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4636 PF15468.6 EMR62065.1 - 0.052 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Peptidase_U4 PF03419.13 EMR62065.1 - 0.27 10.5 6.2 0.42 9.9 6.2 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA GMC_oxred_N PF00732.19 EMR62066.1 - 6.3e-31 107.8 2.2 7.7e-31 107.6 0.3 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR62066.1 - 2.4e-23 83.3 1.9 8.3e-22 78.3 0.1 2.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR62066.1 - 1.4e-06 27.7 0.5 2.5e-06 26.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR62066.1 - 6.4e-06 25.6 0.1 1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR62066.1 - 3.1e-05 23.4 0.8 5.3e-05 22.6 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR62066.1 - 0.00012 22.2 1.1 0.00012 22.2 1.1 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR62066.1 - 0.00046 19.5 0.2 0.0011 18.3 0.2 1.6 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EMR62066.1 - 0.001 18.7 0.8 0.014 15.0 0.4 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR62066.1 - 0.0023 16.7 1.4 0.0042 15.8 0.4 1.9 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 EMR62066.1 - 0.016 15.7 0.1 0.042 14.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR62066.1 - 0.019 14.3 1.6 0.038 13.4 1.6 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Myc_N PF01056.18 EMR62066.1 - 0.02 14.8 0.7 0.033 14.1 0.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region UDPG_MGDP_dh_N PF03721.14 EMR62066.1 - 0.035 13.7 3.3 0.053 13.1 3.3 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EMR62066.1 - 0.037 13.9 0.1 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAM176 PF14851.6 EMR62066.1 - 0.47 10.1 3.5 4.6 6.9 1.3 2.2 2 0 0 2 2 2 0 FAM176 family LRR_4 PF12799.7 EMR62067.1 - 0.29 11.6 7.1 11 6.6 0.3 3.8 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMR62067.1 - 2.9 7.7 5.3 8.2 6.3 0.8 2.9 2 1 0 2 2 2 0 Leucine rich repeat DUF155 PF02582.14 EMR62069.1 - 1.9e-51 174.6 0.1 3.8e-51 173.7 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 EMR62069.1 - 0.057 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator ADH_N PF08240.12 EMR62070.1 - 1.4e-06 28.1 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.8 EMR62072.1 - 0.00064 18.6 0.1 0.00072 18.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 EMR62073.1 - 1.1e-12 47.9 0.4 1.1e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 EMR62073.1 - 2.2e-05 23.7 0.3 4.1e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR62073.1 - 0.00021 21.0 0.8 0.005 16.5 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR62073.1 - 0.00058 20.0 0.6 0.0019 18.4 0.4 2.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR62073.1 - 0.0017 17.8 0.1 0.003 17.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR62073.1 - 0.0077 15.5 0.1 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR62073.1 - 0.011 14.5 0.2 0.019 13.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EMR62073.1 - 0.053 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR62073.1 - 0.1 11.8 0.1 2.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 EMR62073.1 - 0.38 10.0 1.8 0.39 10.0 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SUR7 PF06687.12 EMR62074.1 - 2.6e-06 27.2 7.9 4.4e-06 26.5 7.2 1.6 1 1 0 1 1 1 1 SUR7/PalI family GFO_IDH_MocA PF01408.22 EMR62075.1 - 4.2e-15 56.6 0.0 8.6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMR62075.1 - 1e-05 25.5 0.0 4e-05 23.6 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ImpA_N PF06812.12 EMR62075.1 - 0.0077 16.3 0.1 0.036 14.2 0.0 2.1 3 0 0 3 3 3 1 ImpA, N-terminal, type VI secretion system Whib PF02467.16 EMR62075.1 - 0.069 13.8 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Transcription factor WhiB Peptidase_M10 PF00413.24 EMR62077.1 - 1.7e-08 34.5 2.7 1.2e-07 31.8 1.8 2.3 2 1 0 2 2 2 1 Matrixin Astacin PF01400.24 EMR62077.1 - 8e-07 28.9 0.0 1.6e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 EMR62077.1 - 0.0017 18.0 0.4 0.0027 17.4 0.4 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 EMR62077.1 - 0.0042 17.6 0.0 0.0071 16.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EMR62077.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EMR62077.1 - 0.019 14.2 0.1 0.03 13.6 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 EMR62077.1 - 0.021 15.0 0.1 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EMR62077.1 - 0.031 14.2 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3267 PF11667.8 EMR62077.1 - 0.054 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative zincin peptidase Peptidase_M66 PF10462.9 EMR62077.1 - 0.23 10.3 0.3 0.42 9.5 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Erv26 PF04148.13 EMR62080.1 - 1.7e-91 305.6 1.8 2e-91 305.4 1.8 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.20 EMR62080.1 - 0.002 18.0 0.1 0.002 18.0 0.1 1.8 2 1 0 2 2 2 1 Cytochrome C assembly protein DUF3377 PF11857.8 EMR62080.1 - 0.0072 16.2 0.2 0.063 13.2 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3377) DUF1970 PF09301.10 EMR62080.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) SprT-like PF10263.9 EMR62081.1 - 0.00034 20.4 0.4 0.0014 18.5 0.4 2.0 1 1 0 1 1 1 1 SprT-like family DUF1996 PF09362.10 EMR62083.1 - 8.4e-82 274.7 0.6 1.1e-81 274.3 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Aldo_ket_red PF00248.21 EMR62084.1 - 5e-41 140.8 0.0 8e-39 133.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ABC_tran PF00005.27 EMR62085.1 - 3.4e-51 173.3 0.1 2.6e-27 96.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMR62085.1 - 3.9e-20 72.9 5.0 1.6e-05 24.9 0.0 4.9 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EMR62085.1 - 1.5e-14 53.8 23.6 1.5e-14 53.8 23.6 2.7 3 0 0 3 3 3 1 ABC-2 family transporter protein SMC_N PF02463.19 EMR62085.1 - 7e-08 32.2 0.1 1.1 8.7 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMR62085.1 - 3.9e-07 30.8 0.3 0.035 14.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EMR62085.1 - 1.1e-06 28.7 0.1 0.02 14.8 0.1 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_29 PF13555.6 EMR62085.1 - 9.1e-06 25.3 0.7 0.065 13.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMR62085.1 - 3.6e-05 23.7 0.1 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EMR62085.1 - 7.2e-05 23.1 0.0 0.41 10.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EMR62085.1 - 8.5e-05 22.3 0.4 0.34 10.6 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EMR62085.1 - 0.00013 22.4 0.0 0.5 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EMR62085.1 - 0.00016 21.5 0.0 0.12 12.1 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain SRP54 PF00448.22 EMR62085.1 - 0.00023 20.8 0.3 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EMR62085.1 - 0.0088 15.8 0.1 2 8.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EMR62085.1 - 0.014 15.8 1.8 7.8 6.9 0.3 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EMR62085.1 - 0.017 14.7 0.1 6.3 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4162 PF13732.6 EMR62085.1 - 0.021 15.5 0.0 0.23 12.2 0.0 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF4162) RNA_helicase PF00910.22 EMR62085.1 - 0.025 15.0 0.0 2.9 8.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 EMR62085.1 - 0.027 13.7 0.1 7.6 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_PrkA PF08298.11 EMR62085.1 - 0.027 13.4 0.0 3.6 6.4 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain AAA_19 PF13245.6 EMR62085.1 - 0.028 14.8 0.1 4.5 7.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMR62085.1 - 0.038 14.0 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMR62085.1 - 0.085 13.1 1.6 7.1 6.9 0.3 2.9 4 0 0 4 4 2 0 AAA domain IstB_IS21 PF01695.17 EMR62085.1 - 0.086 12.6 0.1 26 4.5 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein NACHT PF05729.12 EMR62085.1 - 0.12 12.3 0.3 8.5 6.3 0.1 2.8 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EMR62085.1 - 0.14 12.2 0.3 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EMR62085.1 - 0.14 12.3 0.4 16 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 EMR62085.1 - 0.17 11.4 0.7 8.2 6.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 EMR62085.1 - 0.27 10.4 0.1 3.3 6.8 0.1 2.1 2 0 0 2 2 2 0 G-protein alpha subunit LIDHydrolase PF10230.9 EMR62085.1 - 0.73 9.3 2.4 0.36 10.3 0.0 1.6 2 0 0 2 2 1 0 Lipid-droplet associated hydrolase DUF1700 PF08006.11 EMR62085.1 - 0.99 8.9 12.1 2.9 7.4 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) T2SSE PF00437.20 EMR62085.1 - 4.1 6.4 5.9 3.9 6.4 0.1 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein DUF3602 PF12223.8 EMR62086.1 - 2.1e-21 76.3 6.4 2.1e-21 76.3 6.4 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) WBS_methylT PF12589.8 EMR62087.1 - 1.5e-14 54.5 3.9 3e-14 53.5 3.9 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EMR62087.1 - 4.9e-11 43.1 0.0 8.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR62087.1 - 1.9e-09 38.1 0.0 4.9e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR62087.1 - 0.00019 22.1 0.0 0.00051 20.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMR62087.1 - 0.00048 20.0 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EMR62087.1 - 0.0017 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMR62087.1 - 0.0052 16.1 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EMR62087.1 - 0.054 13.3 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EMR62087.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 EMR62087.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 EMR62088.1 - 0.0013 19.2 0.2 0.0037 17.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMR62088.1 - 0.0038 17.8 0.0 0.015 15.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMR62088.1 - 0.006 17.0 0.0 0.0098 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR62088.1 - 0.028 14.7 0.1 0.058 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMR62088.1 - 0.033 13.9 0.2 0.061 13.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EMR62088.1 - 0.049 13.0 0.2 0.087 12.2 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 EMR62088.1 - 0.056 13.6 0.4 0.23 11.5 0.2 2.0 2 1 0 2 2 2 0 Torsin AAA_5 PF07728.14 EMR62088.1 - 0.079 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EMR62088.1 - 0.08 12.5 0.4 0.16 11.5 0.4 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMR62088.1 - 0.099 11.9 0.2 0.57 9.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EMR62088.1 - 0.099 13.0 0.3 0.23 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EMR62088.1 - 0.55 10.0 2.1 0.67 9.7 0.8 2.0 2 1 0 2 2 2 0 AAA domain DUF1524 PF07510.11 EMR62090.1 - 3.8e-08 33.3 0.0 4.8e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) MFS_1 PF07690.16 EMR62091.1 - 1.1e-25 90.4 24.9 1.1e-25 90.3 20.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Ubiquitin_5 PF18037.1 EMR62092.1 - 0.036 14.4 0.4 2.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DWNN PF08783.11 EMR62092.1 - 0.098 13.0 0.4 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 DWNN domain ResIII PF04851.15 EMR62093.1 - 1.2e-13 51.4 0.0 1.5e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMR62093.1 - 3.2e-10 40.1 0.0 4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EMR62093.1 - 0.00015 21.5 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 SWI2/SNF2 ATPase BCOR PF15808.5 EMR62094.1 - 0.039 14.2 5.0 0.11 12.7 5.1 1.6 1 1 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region Exonuc_VII_L PF02601.15 EMR62094.1 - 0.19 11.3 4.0 0.21 11.1 4.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_Maf PF03131.17 EMR62095.1 - 0.12 13.0 2.6 0.33 11.5 2.6 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor SesA PF17107.5 EMR62096.1 - 0.009 16.2 0.7 0.014 15.6 0.6 1.4 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Terminase_4 PF05119.12 EMR62096.1 - 0.021 15.3 0.5 1.8 9.0 0.0 2.2 1 1 1 2 2 2 0 Phage terminase, small subunit DUF948 PF06103.11 EMR62096.1 - 0.03 14.6 2.1 0.053 13.8 0.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.15 EMR62096.1 - 0.073 13.5 0.6 0.2 12.0 0.5 1.9 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus MSC PF09402.10 EMR62097.1 - 2.1e-112 375.9 0.0 2.8e-112 375.5 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EMR62097.1 - 5.6e-16 58.0 0.1 1.1e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 EMR62097.1 - 0.19 11.4 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 Thymopoietin protein RRM_1 PF00076.22 EMR62098.1 - 1.2e-38 130.7 0.2 8e-19 67.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR62098.1 - 0.0038 17.3 0.1 0.26 11.4 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 EMR62098.1 - 0.058 13.2 1.6 0.62 9.8 0.0 2.7 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain NDUFB10 PF10249.9 EMR62099.1 - 0.011 16.2 0.1 0.012 16.1 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 EMR62099.1 - 0.057 14.1 0.0 0.084 13.6 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase TAP_C PF03943.13 EMR62100.1 - 3.7e-18 64.9 0.4 7e-18 64.0 0.4 1.5 1 0 0 1 1 1 1 TAP C-terminal domain RRM_9 PF18444.1 EMR62100.1 - 9.7e-05 22.1 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif LRR_4 PF12799.7 EMR62100.1 - 0.0002 21.7 0.6 0.017 15.6 0.1 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) NTF2 PF02136.20 EMR62100.1 - 0.0017 18.9 0.0 0.0048 17.5 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 EMR62100.1 - 0.15 11.8 0.4 0.38 10.6 0.4 1.7 1 0 0 1 1 1 0 Leucine rich repeat Amidoligase_2 PF12224.8 EMR62101.1 - 4.8e-07 29.7 0.0 2.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme DUF3439 PF11921.8 EMR62101.1 - 0.091 12.7 1.9 0.16 11.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) GST_N PF02798.20 EMR62102.1 - 1.1e-20 73.7 0.0 2.3e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR62102.1 - 4.3e-17 62.1 0.0 1.9e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR62102.1 - 1e-15 57.8 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR62102.1 - 9e-15 54.9 0.0 1.8e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR62102.1 - 1.2e-10 41.5 0.0 3.8e-09 36.6 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR62102.1 - 5.2e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EMR62102.1 - 0.066 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EMR62102.1 - 0.14 13.0 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain FMO-like PF00743.19 EMR62103.1 - 8.3e-18 64.1 0.0 1.9e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMR62103.1 - 4.4e-07 29.4 0.0 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR62103.1 - 1.1e-06 28.8 0.0 3.1e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EMR62103.1 - 4.9e-05 22.6 0.0 0.0032 16.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMR62103.1 - 0.0016 17.8 0.0 0.036 13.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EMR62103.1 - 0.026 14.6 0.0 0.4 10.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 EMR62104.1 - 1.4e-31 109.8 22.1 2.3e-31 109.0 21.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 EMR62104.1 - 3.3 7.4 0.0 3.3 7.4 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) adh_short_C2 PF13561.6 EMR62105.1 - 2.6e-53 181.0 0.2 3.1e-53 180.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR62105.1 - 2.7e-43 147.7 0.2 3.3e-43 147.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR62105.1 - 4.8e-09 36.4 0.7 1.2e-08 35.1 0.7 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR62105.1 - 0.00018 21.1 0.1 0.00046 19.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_18 PF13238.6 EMR62106.1 - 0.00022 21.8 0.0 0.00043 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EMR62106.1 - 0.00048 20.1 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.22 EMR62106.1 - 0.00069 19.3 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 EMR62106.1 - 0.0019 17.3 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EMR62106.1 - 0.002 18.5 0.1 0.0046 17.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 EMR62106.1 - 0.0054 16.0 0.0 0.0059 15.9 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain PRK PF00485.18 EMR62106.1 - 0.007 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 EMR62106.1 - 0.0093 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EMR62106.1 - 0.012 15.6 0.2 0.031 14.3 0.2 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EMR62106.1 - 0.013 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 EMR62106.1 - 0.015 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EMR62106.1 - 0.021 15.4 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EMR62106.1 - 0.021 15.0 0.1 0.079 13.1 0.0 2.1 2 1 1 3 3 3 0 AAA domain cobW PF02492.19 EMR62106.1 - 0.03 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EMR62106.1 - 0.043 13.8 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EMR62106.1 - 0.044 13.0 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ArsA_ATPase PF02374.15 EMR62106.1 - 0.046 12.9 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase NTPase_1 PF03266.15 EMR62106.1 - 0.096 12.6 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.17 EMR62106.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_31 PF13614.6 EMR62106.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 EMR62108.1 - 3.5 6.3 3.5 3.8 6.2 3.5 1.0 1 0 0 1 1 1 0 Presenilin KH_1 PF00013.29 EMR62109.1 - 9.7e-48 159.9 12.9 3.2e-16 58.9 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EMR62109.1 - 8.9e-12 44.7 3.5 0.015 15.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EMR62109.1 - 1.4e-09 37.6 3.4 0.11 12.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EMR62109.1 - 0.00027 21.0 1.7 8.8 6.5 0.0 3.5 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 EMR62109.1 - 0.00073 19.5 0.0 3.6 7.6 0.0 3.0 3 0 0 3 3 3 2 KH-like RNA-binding domain Homeodomain PF00046.29 EMR62110.1 - 4e-20 71.4 4.7 7.7e-20 70.5 4.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EMR62110.1 - 0.0012 18.7 0.6 0.0029 17.5 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain AsmA_1 PF13109.6 EMR62110.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 AsmA-like C-terminal region Tho2 PF11262.8 EMR62110.1 - 0.14 11.3 0.8 0.19 10.9 0.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Menin PF05053.13 EMR62111.1 - 0.75 8.1 3.2 1.1 7.5 3.2 1.2 1 0 0 1 1 1 0 Menin RPN2_C PF18004.1 EMR62111.1 - 1.5 8.8 11.1 0.18 11.7 6.7 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4187 PF13821.6 EMR62112.1 - 5.6e-22 77.3 2.3 1.2e-21 76.2 2.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EMR62112.1 - 4.9e-07 29.5 0.3 0.00076 19.3 0.1 2.6 2 0 0 2 2 2 2 G-patch domain Pkinase PF00069.25 EMR62113.1 - 2e-32 112.6 0.0 2.8e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR62113.1 - 4.9e-11 42.4 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EMR62113.1 - 3.7e-06 27.0 0.1 5.7e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EMR62113.1 - 0.015 14.7 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like SR-25 PF10500.9 EMR62114.1 - 0.0023 17.6 1.1 0.0023 17.6 1.1 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein BTB PF00651.31 EMR62114.1 - 0.0084 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain FXR_C1 PF16096.5 EMR62114.1 - 0.6 10.4 12.5 1.6 9.0 12.5 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 CCDC106 PF15794.5 EMR62114.1 - 0.7 9.6 5.1 1.2 8.7 5.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ribosomal_L10 PF00466.20 EMR62116.1 - 2.1e-23 82.3 0.5 5.5e-23 81.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EMR62116.1 - 3.5e-22 78.2 0.0 6.5e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EMR62116.1 - 2.3e-15 56.9 6.5 2.5e-15 56.8 4.1 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein VirE_N PF08800.10 EMR62116.1 - 0.008 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 VirE N-terminal domain CAP_GLY PF01302.25 EMR62117.1 - 3.3e-16 59.0 0.2 7.1e-16 58.0 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 EMR62117.1 - 2.1e-09 37.0 11.1 1.7e-05 24.5 1.1 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle BLOC1_2 PF10046.9 EMR62117.1 - 0.013 15.8 8.6 0.42 11.0 1.9 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EMR62117.1 - 0.017 15.6 6.1 0.7 10.4 0.7 2.9 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Sec2p PF06428.11 EMR62117.1 - 0.019 14.9 0.6 0.019 14.9 0.6 4.3 4 1 1 5 5 4 0 GDP/GTP exchange factor Sec2p DUF305 PF03713.13 EMR62117.1 - 0.039 14.1 10.7 0.1 12.8 6.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF305) Spc7 PF08317.11 EMR62117.1 - 0.1 11.5 26.9 0.068 12.0 0.9 3.4 3 1 1 4 4 4 0 Spc7 kinetochore protein DUF812 PF05667.11 EMR62117.1 - 0.12 11.3 26.8 0.16 10.8 14.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF812) BAR_2 PF10455.9 EMR62117.1 - 0.15 11.2 18.6 3.5 6.7 10.0 2.3 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking C1_2 PF03107.16 EMR62117.1 - 0.15 12.4 1.7 10 6.5 0.2 2.4 2 0 0 2 2 2 0 C1 domain Baculo_PEP_C PF04513.12 EMR62117.1 - 0.32 11.0 2.8 4.5 7.3 0.9 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.13 EMR62117.1 - 0.33 11.3 30.8 0.02 15.2 9.3 4.0 1 1 4 5 5 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF241 PF03087.14 EMR62117.1 - 0.37 10.6 10.8 0.048 13.5 0.8 3.1 3 0 0 3 3 3 0 Arabidopsis protein of unknown function Fez1 PF06818.15 EMR62117.1 - 0.37 11.2 32.5 27 5.2 2.7 3.5 1 1 1 2 2 2 0 Fez1 Flagellin_N PF00669.20 EMR62117.1 - 0.45 10.6 7.4 0.43 10.7 0.4 3.2 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region XLF PF09302.11 EMR62117.1 - 0.5 10.5 4.7 16 5.6 0.1 3.5 2 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component zf_PR_Knuckle PF18445.1 EMR62117.1 - 0.77 9.6 2.6 6.8 6.6 0.1 2.3 2 0 0 2 2 2 0 PR zinc knuckle motif DUF4407 PF14362.6 EMR62117.1 - 0.86 8.9 24.2 0.14 11.5 11.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DLP_helical PF18709.1 EMR62117.1 - 0.93 8.6 10.9 0.11 11.7 3.5 2.2 2 0 0 2 2 2 0 Dynamin-like helical domain Sec8_exocyst PF04048.14 EMR62117.1 - 1.1 9.1 4.4 4.3 7.2 0.3 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain HrpB7 PF09486.10 EMR62117.1 - 1.2 9.6 26.7 0.16 12.3 0.3 3.4 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) MscS_porin PF12795.7 EMR62117.1 - 1.4 8.4 26.2 0.36 10.3 4.8 3.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DivIC PF04977.15 EMR62117.1 - 1.7 8.4 0.0 1.7 8.4 0.0 5.1 5 1 1 6 6 6 0 Septum formation initiator Fib_alpha PF08702.10 EMR62117.1 - 3.1 8.0 15.7 9.1 6.5 0.2 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF3349 PF11829.8 EMR62117.1 - 3.4 8.5 5.7 2.4 9.0 0.7 2.8 2 1 0 3 3 2 0 Protein of unknown function (DUF3349) TMF_DNA_bd PF12329.8 EMR62117.1 - 3.9 7.6 38.4 0.082 12.9 3.9 5.4 4 2 0 4 4 4 0 TATA element modulatory factor 1 DNA binding EMP24_GP25L PF01105.24 EMR62117.1 - 5.4 6.9 7.9 5 7.0 0.8 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF465 PF04325.13 EMR62117.1 - 6.4 6.9 9.2 1.4 9.1 0.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF465) DHR10 PF18595.1 EMR62117.1 - 7 6.7 41.1 0.22 11.6 10.0 4.3 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EMR62117.1 - 8.5 6.5 20.9 5.8 7.1 3.6 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) MutS_V PF00488.21 EMR62118.1 - 2e-58 197.5 0.1 7.1e-58 195.7 0.1 1.7 1 1 0 1 1 1 1 MutS domain V BAH PF01426.18 EMR62119.1 - 1.1e-05 25.3 0.0 9e-05 22.3 0.1 2.6 3 2 0 3 3 3 1 BAH domain GATA PF00320.27 EMR62119.1 - 0.047 13.3 0.5 0.047 13.3 0.5 2.3 2 0 0 2 2 2 0 GATA zinc finger ELM2 PF01448.24 EMR62119.1 - 0.28 12.0 9.6 0.096 13.5 4.3 3.0 2 1 0 2 2 2 0 ELM2 domain USP19_linker PF16602.5 EMR62120.1 - 0.014 15.9 8.1 1 9.9 2.0 2.4 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase NSP2_assoc PF14758.6 EMR62120.1 - 0.029 14.7 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein WD40 PF00400.32 EMR62120.1 - 0.14 13.1 1.1 3.9 8.5 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat MxiM PF11441.8 EMR62120.1 - 0.17 12.2 0.0 0.67 10.3 0.0 1.8 1 1 0 2 2 2 0 Pilot protein MxiM Nop14 PF04147.12 EMR62121.1 - 4.6e-229 763.0 59.9 1.2e-179 599.5 34.8 2.1 1 1 1 2 2 2 2 Nop14-like family MFS_1 PF07690.16 EMR62122.1 - 1.2e-17 63.9 26.2 1.2e-17 63.9 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR62122.1 - 0.0079 15.1 25.1 0.06 12.2 20.0 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter DUF2811 PF10929.8 EMR62122.1 - 0.09 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) EF-hand_6 PF13405.6 EMR62123.1 - 1.1e-07 31.2 0.8 0.00056 19.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EMR62123.1 - 2.1e-07 31.3 0.9 2.1e-07 31.3 0.9 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EMR62123.1 - 4e-05 22.9 0.8 0.00028 20.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EMR62123.1 - 4.8e-05 22.7 1.0 8.3e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EMR62123.1 - 0.029 14.2 0.1 0.082 12.8 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair NUDIX PF00293.28 EMR62124.1 - 3.5e-20 72.4 1.9 4.5e-20 72.0 1.9 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EMR62124.1 - 0.0071 16.3 0.2 0.016 15.2 0.2 1.7 1 1 0 1 1 1 1 NUDIX domain adh_short_C2 PF13561.6 EMR62128.1 - 1.4e-57 195.0 3.9 1.6e-57 194.8 3.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR62128.1 - 1.9e-46 158.0 0.5 2.3e-46 157.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR62128.1 - 8.6e-09 35.6 0.7 2.1e-08 34.3 0.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR62128.1 - 0.0058 16.1 0.2 0.016 14.7 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribosomal_S11 PF00411.19 EMR62128.1 - 0.11 12.9 2.6 0.1 13.0 0.8 1.9 2 0 0 2 2 2 0 Ribosomal protein S11 CVNH PF08881.10 EMR62129.1 - 4.5e-07 30.5 0.0 6.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 CVNH domain ORC6 PF05460.13 EMR62130.1 - 6.7e-35 121.0 0.1 1.2e-34 120.2 0.1 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) TFIIB_C_1 PF18542.1 EMR62130.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 Glyco_hydro_12 PF01670.16 EMR62131.1 - 1.3e-46 159.3 7.9 1.5e-46 159.1 7.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5_1 PF06946.11 EMR62131.1 - 1.3 9.4 7.5 0.42 11.0 1.8 2.5 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 Mito_carr PF00153.27 EMR62132.1 - 2.8e-43 145.8 8.5 2.4e-15 56.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Osmo_MPGsynth PF09488.10 EMR62133.1 - 6.2e-159 528.8 0.0 7.4e-159 528.6 0.0 1.1 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) PhyH PF05721.13 EMR62135.1 - 2e-18 67.4 0.0 3.8e-18 66.5 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GNAT_acetyltr_2 PF13718.6 EMR62136.1 - 1.3e-95 319.1 0.0 2.5e-95 318.2 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EMR62136.1 - 9.5e-90 300.4 0.0 1.6e-89 299.7 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EMR62136.1 - 3.2e-66 222.5 0.1 1.6e-65 220.3 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EMR62136.1 - 1.9e-32 111.1 0.3 8.2e-32 109.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 EMR62136.1 - 0.0002 21.6 0.0 0.067 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EMR62136.1 - 0.00096 18.9 0.0 0.072 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF3336 PF11815.8 EMR62137.1 - 1e-34 119.2 0.2 4.3e-34 117.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EMR62137.1 - 4.9e-19 69.3 0.0 8e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase p450 PF00067.22 EMR62138.1 - 3.5e-69 233.8 0.0 4.1e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AhpC-TSA PF00578.21 EMR62139.1 - 3.2e-29 101.4 0.0 4.3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EMR62139.1 - 4.1e-12 45.7 0.2 8.9e-12 44.7 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EMR62139.1 - 2e-11 43.8 0.0 2.7e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin NMT_C PF02799.15 EMR62140.1 - 3e-84 281.7 0.1 4.4e-84 281.2 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EMR62140.1 - 1.3e-74 249.4 0.1 4.3e-74 247.7 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EMR62140.1 - 0.031 14.4 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dynamin_N PF00350.23 EMR62142.1 - 1.3e-31 109.9 0.4 4.6e-31 108.1 0.1 2.1 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EMR62142.1 - 5.8e-24 84.8 0.0 9.1e-20 71.0 0.0 2.5 2 1 1 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.23 EMR62142.1 - 6.7e-06 26.2 0.1 4.1e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 EMR62142.1 - 2.8e-05 24.2 0.2 9.2e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain Roc PF08477.13 EMR62142.1 - 0.0056 16.9 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase HAD PF12710.7 EMR62142.1 - 0.0066 16.9 0.1 0.45 10.9 0.0 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 EMR62142.1 - 0.012 16.0 0.5 0.088 13.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 EMR62142.1 - 0.019 14.8 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 EMR62142.1 - 0.046 13.3 0.0 6.9 6.2 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_15 PF13175.6 EMR62142.1 - 0.056 13.1 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EMR62142.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DivIC PF04977.15 EMR62142.1 - 2.6 7.9 6.8 41 4.0 0.0 4.4 4 0 0 4 4 4 0 Septum formation initiator ZZ PF00569.17 EMR62143.1 - 6.5e-10 38.7 6.1 1.3e-09 37.7 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 EMR62143.1 - 3.8e-09 35.4 4.6 0.0022 17.4 0.4 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EMR62143.1 - 6.2e-06 26.6 11.7 6.5e-05 23.3 4.9 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 EMR62143.1 - 1.9e-05 24.2 4.9 0.018 15.0 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EMR62143.1 - 0.0011 18.7 0.9 1.7 8.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair C1_2 PF03107.16 EMR62143.1 - 0.018 15.3 5.6 0.035 14.4 5.6 1.4 1 0 0 1 1 1 0 C1 domain CPSF100_C PF13299.6 EMR62143.1 - 0.42 10.8 2.5 1.5 9.0 2.5 1.9 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EF-hand_5 PF13202.6 EMR62143.1 - 0.75 9.4 2.6 14 5.4 0.1 3.0 3 0 0 3 3 3 0 EF hand DUF4611 PF15387.6 EMR62143.1 - 2.2 8.5 16.8 0.5 10.6 3.8 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) PEP_mutase PF13714.6 EMR62144.1 - 7.1e-36 123.8 0.1 9.2e-36 123.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EMR62144.1 - 4.1e-10 38.8 0.0 7e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Peptidase_M50B PF13398.6 EMR62145.1 - 2.2e-57 194.0 21.9 2.7e-57 193.7 21.9 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 EMR62145.1 - 0.021 14.1 0.3 0.058 12.6 0.1 1.8 2 0 0 2 2 2 0 Peptidase family M50 Abhydrolase_1 PF00561.20 EMR62146.1 - 5.1e-25 88.6 0.0 7.8e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR62146.1 - 7.1e-12 46.4 0.0 8.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR62146.1 - 1.2e-07 31.3 0.0 2.3e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 tRNA-synt_1c PF00749.21 EMR62147.1 - 3.1e-54 184.0 0.0 4e-34 117.9 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EMR62147.1 - 1.2e-28 100.2 0.0 6.1e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain LepB_GAP_N PF18172.1 EMR62147.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain Sugar_tr PF00083.24 EMR62148.1 - 2.2e-60 204.8 8.1 4.6e-55 187.3 3.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter NmrA PF05368.13 EMR62148.1 - 0.055 13.0 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Colicin_V PF02674.16 EMR62148.1 - 3.2 7.7 11.6 0.095 12.7 2.2 2.7 2 2 0 2 2 2 0 Colicin V production protein Abhydrolase_6 PF12697.7 EMR62149.1 - 1e-08 36.0 0.2 1.3e-08 35.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR62149.1 - 1.4e-08 34.3 0.2 3.2e-08 33.1 0.2 1.4 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR62149.1 - 3.1e-05 23.8 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EMR62149.1 - 0.00015 21.7 0.1 0.00027 20.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR62149.1 - 0.00039 20.0 0.5 0.0029 17.1 0.7 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EMR62149.1 - 0.00061 19.5 0.4 0.00084 19.0 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Cutinase PF01083.22 EMR62149.1 - 0.043 13.8 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 Cutinase SHMT PF00464.19 EMR62149.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Exo_endo_phos PF03372.23 EMR62150.1 - 0.0023 17.5 0.0 0.0026 17.3 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Zn_clus PF00172.18 EMR62151.1 - 3.5e-14 52.6 19.7 1.2e-08 34.9 10.7 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR62151.1 - 4.4e-13 48.9 0.6 4.4e-13 48.9 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Spt20 PF12090.8 EMR62151.1 - 1.3 8.5 10.1 2.2 7.8 10.1 1.3 1 0 0 1 1 1 0 Spt20 family NmrA PF05368.13 EMR62152.1 - 7.3e-26 91.2 0.0 1.9e-25 89.8 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR62152.1 - 8.9e-08 32.2 0.0 2e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding ADH_N PF08240.12 EMR62153.1 - 8e-06 25.7 0.0 6.3e-05 22.8 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR62153.1 - 0.028 14.4 0.7 0.061 13.3 0.7 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DnaJ PF00226.31 EMR62155.1 - 3e-09 36.8 0.0 6.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain NOA36 PF06524.12 EMR62156.1 - 0.036 13.4 6.1 0.053 12.9 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EMR62156.1 - 0.039 14.0 1.4 0.08 13.0 1.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal AAA PF00004.29 EMR62156.1 - 0.043 14.2 0.2 0.19 12.2 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PBP1_TM PF14812.6 EMR62156.1 - 0.29 11.5 10.3 1.1 9.7 10.3 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Iso_dh PF00180.20 EMR62157.1 - 1e-86 291.3 0.0 1.2e-86 291.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NAD_binding_1 PF00175.21 EMR62158.1 - 2.1e-31 108.8 0.0 3.4e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMR62158.1 - 1e-26 93.2 0.0 1.6e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EMR62158.1 - 5.8e-22 77.6 0.2 1.1e-21 76.7 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EMR62158.1 - 9.5e-06 25.8 0.0 0.0017 18.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EMR62158.1 - 0.02 15.1 0.0 0.069 13.4 0.0 1.9 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain Glyco_hydro_43 PF04616.14 EMR62159.1 - 6.5e-54 183.2 5.2 8.1e-54 182.9 5.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EMR62159.1 - 8.9e-06 25.5 3.1 8.9e-06 25.5 0.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_130 PF04041.13 EMR62159.1 - 0.017 14.1 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 beta-1,4-mannooligosaccharide phosphorylase DUF4448 PF14610.6 EMR62160.1 - 3.2e-42 144.5 0.2 4.4e-42 144.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Kringle PF00051.18 EMR62160.1 - 0.11 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Kringle domain Abhydrolase_1 PF00561.20 EMR62161.1 - 6.1e-15 55.6 0.0 1.1e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR62161.1 - 4.2e-12 47.2 0.4 5.7e-12 46.7 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR62161.1 - 1.8e-11 43.8 0.0 1.6e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EMR62161.1 - 0.009 16.1 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein DUF1100 PF06500.11 EMR62161.1 - 0.021 13.7 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.12 EMR62161.1 - 0.029 14.3 0.0 6.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 EMR62161.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR62161.1 - 0.15 11.5 0.0 15 5.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Amidoligase_2 PF12224.8 EMR62162.1 - 5.9e-11 42.5 0.1 2.2e-09 37.3 0.1 2.2 1 1 0 2 2 2 2 Putative amidoligase enzyme DcpS PF05652.12 EMR62163.1 - 1e-27 97.0 0.0 2.2e-26 92.7 0.0 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EMR62163.1 - 2.2e-21 76.5 0.0 3.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Fungal_trans PF04082.18 EMR62164.1 - 5.7e-27 94.4 0.0 4e-26 91.6 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_47 PF01532.20 EMR62165.1 - 5e-95 319.1 0.0 6.8e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MFS_1 PF07690.16 EMR62166.1 - 8.2e-33 113.8 45.9 8.2e-33 113.8 45.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR62166.1 - 3.1e-10 39.1 7.5 3.1e-10 39.1 7.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2937 PF11157.8 EMR62166.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Myb_Cef PF11831.8 EMR62167.1 - 2.1e-49 168.2 6.7 2.1e-49 168.2 6.7 3.8 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EMR62167.1 - 2.8e-23 81.8 5.5 7.1e-11 42.1 1.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR62167.1 - 2.7e-20 72.4 8.3 1.2e-13 51.1 3.5 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EMR62167.1 - 0.099 12.7 0.1 0.099 12.7 0.1 3.3 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain XhlA PF10779.9 EMR62167.1 - 2.2 8.5 4.5 15 5.9 0.5 3.6 1 1 1 2 2 2 0 Haemolysin XhlA GILT PF03227.16 EMR62168.1 - 3e-18 66.0 0.3 3e-18 66.0 0.3 1.7 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Na_Ca_ex PF01699.24 EMR62169.1 - 2.8e-37 128.0 36.3 5.9e-22 78.3 17.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YqfQ PF14181.6 EMR62170.1 - 0.15 12.2 4.0 0.17 12.0 4.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein Ank_5 PF13857.6 EMR62172.1 - 0.00025 21.3 0.1 0.00083 19.6 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR62172.1 - 0.00079 19.9 0.0 0.005 17.4 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EMR62172.1 - 0.0011 19.4 0.0 0.0046 17.3 0.0 2.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EMR62172.1 - 0.061 13.9 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Glyco_hydro_76 PF03663.14 EMR62175.1 - 7.8e-133 443.5 4.0 1e-132 443.2 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TauD PF02668.16 EMR62176.1 - 3.2e-41 141.9 0.3 4.6e-41 141.4 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.11 EMR62176.1 - 0.03 13.7 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DNA_pol3_a_NII PF11490.8 EMR62177.1 - 1.1 9.2 6.1 0.14 12.0 0.6 1.9 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II Peptidase_S64 PF08192.11 EMR62177.1 - 4.6 5.6 5.4 5.9 5.3 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 FUSC PF04632.12 EMR62177.1 - 7.8 4.9 10.3 10 4.5 10.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family p450 PF00067.22 EMR62178.1 - 2.4e-43 148.6 0.0 2.8e-42 145.0 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 SUZ PF12752.7 EMR62178.1 - 8.2 7.3 6.7 0.54 11.1 0.8 2.0 2 0 0 2 2 2 0 SUZ domain Sulfatase PF00884.23 EMR62179.1 - 2.6e-46 158.5 0.0 3.8e-45 154.6 0.0 2.2 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EMR62179.1 - 0.017 15.4 0.1 0.033 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Amidase PF01425.21 EMR62180.1 - 6.2e-27 94.7 4.9 1.5e-21 76.9 5.3 3.8 3 1 0 3 3 3 3 Amidase GWT1 PF06423.12 EMR62181.1 - 2.9e-43 147.6 0.6 9.8e-43 145.8 1.0 1.7 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 EMR62181.1 - 0.0016 18.9 1.8 0.0026 18.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4818) tRNA-synt_1b PF00579.25 EMR62182.1 - 3.6e-59 200.5 0.1 5.1e-59 200.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PAP_central PF04928.17 EMR62183.1 - 1.1e-20 73.6 0.0 2.4e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 EMR62183.1 - 2.1e-20 73.2 0.7 5.1e-20 72.0 0.7 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain NTP_transf_2 PF01909.23 EMR62183.1 - 9.9e-05 22.6 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EMR62183.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain ClpS PF02617.17 EMR62184.1 - 1e-05 25.2 0.0 2.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 EMR62184.1 - 7.8e-05 22.8 2.3 0.00013 22.1 0.2 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.25 EMR62185.1 - 0.058 12.7 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain HAD_2 PF13419.6 EMR62187.1 - 4.7e-12 46.4 0.0 1.3e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR62187.1 - 3.3e-09 37.4 0.0 1.8e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR62187.1 - 0.0005 20.1 0.0 0.00092 19.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like ApoO PF09769.9 EMR62188.1 - 1e-39 135.5 0.0 2e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein O FKBP_C PF00254.28 EMR62189.1 - 1.8e-31 108.3 0.0 5.9e-31 106.6 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EMR62189.1 - 7.8e-30 103.5 1.3 7.8e-30 103.5 1.3 2.2 2 1 0 2 2 2 1 Nucleoplasmin-like domain DUF572 PF04502.13 EMR62189.1 - 7.3 6.1 24.3 1.4 8.5 6.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Mago-bind PF09282.10 EMR62190.1 - 2.7e-13 49.5 2.1 5.9e-13 48.4 2.1 1.6 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.12 EMR62190.1 - 0.65 9.8 7.8 0.76 9.6 7.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dynactin_p62 PF05502.13 EMR62190.1 - 1 8.0 4.5 1.4 7.6 4.5 1.1 1 0 0 1 1 1 0 Dynactin p62 family FA_desaturase PF00487.24 EMR62191.1 - 9.1e-21 74.8 30.7 9.1e-21 74.8 30.7 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EMR62191.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Pkinase PF00069.25 EMR62192.1 - 8.1e-31 107.3 0.0 1.6e-22 80.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR62192.1 - 1.9e-12 47.0 0.0 9e-11 41.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EMR62192.1 - 0.0068 16.4 0.4 0.0068 16.4 0.4 2.8 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 EMR62192.1 - 0.43 11.3 4.3 9.5 7.0 4.3 2.5 1 1 0 1 1 1 0 Protein kinase C terminal domain IMS PF00817.20 EMR62193.1 - 4.4e-39 133.9 0.0 9.1e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EMR62193.1 - 9.7e-25 86.8 0.2 2.1e-24 85.7 0.2 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EMR62193.1 - 2.9e-12 47.3 0.0 5.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 EMR62193.1 - 6.2e-08 31.8 30.0 8.9e-05 21.8 1.7 4.8 4 1 1 5 5 4 3 Ubiquitin binding region mCpol PF18182.1 EMR62193.1 - 0.0031 17.8 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 2 1 minimal CRISPR polymerase domain TFIIA PF03153.13 EMR62193.1 - 0.018 15.1 20.8 0.027 14.5 20.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F420_ligase PF01996.16 EMR62193.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase IMS_HHH PF11798.8 EMR62193.1 - 0.099 13.0 0.2 0.62 10.5 0.0 2.4 2 0 0 2 2 2 0 IMS family HHH motif YdaT_toxin PF06254.11 EMR62193.1 - 0.11 13.0 0.1 21 5.7 0.0 2.7 2 0 0 2 2 2 0 Putative bacterial toxin ydaT CsgE PF10627.9 EMR62193.1 - 0.18 12.0 2.6 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Curli assembly protein CsgE Suf PF05843.14 EMR62193.1 - 9.7 6.1 14.6 23 4.9 14.6 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PSRT PF07636.11 EMR62194.1 - 0.048 13.3 1.1 0.12 12.1 1.1 1.6 1 0 0 1 1 1 0 PSRT SUIM_assoc PF16619.5 EMR62194.1 - 0.23 11.6 10.4 0.17 12.0 8.0 2.0 1 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1387 PF07139.11 EMR62194.1 - 1.1 8.9 6.2 0.8 9.4 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) Thioredoxin PF00085.20 EMR62195.1 - 4.5e-27 94.0 0.1 5.2e-27 93.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMR62195.1 - 3.7e-07 30.6 0.2 2.2e-06 28.1 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EMR62195.1 - 2.7e-06 26.9 0.0 3.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EMR62195.1 - 2.8e-05 24.3 0.0 0.0017 18.7 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Glutaredoxin PF00462.24 EMR62195.1 - 0.00025 21.2 0.0 0.0006 20.0 0.0 1.7 1 1 1 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.6 EMR62195.1 - 0.00035 20.3 0.1 0.0004 20.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EMR62195.1 - 0.0017 18.5 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EMR62195.1 - 0.0044 16.9 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMR62195.1 - 0.024 14.3 0.1 0.089 12.5 0.1 1.8 1 1 0 1 1 1 0 Redoxin PspC PF04024.12 EMR62196.1 - 0.043 13.6 0.4 0.098 12.5 0.4 1.5 1 0 0 1 1 1 0 PspC domain Adeno_E3_CR2 PF02439.15 EMR62196.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EMR62196.1 - 0.08 13.8 0.0 0.37 11.7 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HNF-1_N PF04814.13 EMR62196.1 - 2.4 8.7 13.7 0.99 10.0 1.6 2.1 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Mito_carr PF00153.27 EMR62197.1 - 2e-66 219.9 0.5 8.1e-21 73.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EMR62197.1 - 0.019 15.1 0.0 4 7.7 0.0 2.6 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Adaptin_N PF01602.20 EMR62198.1 - 5.5e-19 68.1 0.0 6.3e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Nop14 PF04147.12 EMR62198.1 - 0.42 8.8 23.6 0.66 8.1 23.6 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 EMR62198.1 - 2.7 7.7 22.1 0.8 9.4 17.4 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NPR3 PF03666.13 EMR62198.1 - 4 6.1 5.0 6.7 5.4 5.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Fungal_trans_2 PF11951.8 EMR62199.1 - 1.2e-79 267.9 0.0 1.5e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR62199.1 - 1.9e-06 27.9 9.1 3.2e-06 27.1 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.14 EMR62200.1 - 1.3e-62 211.3 0.0 1.6e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 2OG-FeII_Oxy_3 PF13640.6 EMR62201.1 - 3.8e-08 34.1 0.0 2.2e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WPP PF13943.6 EMR62201.1 - 0.067 13.6 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 WPP domain MFS_1 PF07690.16 EMR62202.1 - 7e-23 81.1 61.5 1.4e-21 76.8 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SAM_2 PF07647.17 EMR62203.1 - 5.5e-06 26.4 0.1 1.2e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EMR62203.1 - 1.3e-05 25.5 0.1 3e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 EMR62203.1 - 0.00055 20.4 0.0 0.0055 17.2 0.0 2.5 1 1 0 1 1 1 1 PH domain SAM_PNT PF02198.16 EMR62203.1 - 0.0012 18.8 0.1 0.0031 17.5 0.1 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 EMR62203.1 - 0.072 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Adaptin_N PF01602.20 EMR62204.1 - 8.5e-31 107.1 0.0 1.1e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EMR62204.1 - 0.0038 17.3 0.1 0.042 13.9 0.0 2.2 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EMR62204.1 - 0.0062 16.7 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 HEAT repeat CDC24_OB2 PF17245.2 EMR62204.1 - 0.025 15.1 0.3 0.032 14.8 0.3 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 2 HEAT_2 PF13646.6 EMR62204.1 - 0.031 14.7 0.2 0.18 12.2 0.0 2.1 1 1 2 3 3 3 0 HEAT repeats Cohesin_HEAT PF12765.7 EMR62204.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 EMR62204.1 - 0.059 12.9 0.2 0.24 10.9 0.0 1.9 1 1 0 2 2 2 0 CLASP N terminal XdhC_C PF13478.6 EMR62205.1 - 0.066 13.7 0.0 0.09 13.3 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain Exo_endo_phos PF03372.23 EMR62206.1 - 6.7e-18 65.1 0.2 1e-17 64.5 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 EMR62207.1 - 1.2e-46 155.8 12.7 2.4e-09 37.6 0.0 8.0 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR62207.1 - 1.7e-20 73.1 0.0 0.0014 18.9 0.0 5.9 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR62207.1 - 8.8e-07 27.9 0.1 0.22 10.2 0.1 4.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EMR62207.1 - 8e-06 25.0 0.0 0.1 11.5 0.0 4.6 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EMR62207.1 - 0.00069 19.5 0.6 2.6 8.1 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EMR62207.1 - 0.0034 16.0 0.2 3.5 6.0 0.0 3.1 3 0 0 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EMR62207.1 - 0.0035 16.2 0.0 0.039 12.7 0.0 2.3 2 0 0 2 2 2 1 Nup133 N terminal like BBS2_Mid PF14783.6 EMR62207.1 - 0.0053 16.8 0.0 0.096 12.7 0.0 2.7 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EMR62207.1 - 0.076 12.3 0.0 8.1 5.7 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain IKI3 PF04762.12 EMR62207.1 - 0.12 10.3 0.0 0.2 9.6 0.0 1.3 1 0 0 1 1 1 0 IKI3 family DHR10 PF18595.1 EMR62208.1 - 1.8e-39 134.4 17.1 1.8e-39 134.4 17.1 4.3 3 1 1 4 4 4 2 Designed helical repeat protein 10 domain Nuf2 PF03800.14 EMR62208.1 - 2.5e-38 131.4 0.0 7e-38 129.9 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family PI3K_P85_iSH2 PF16454.5 EMR62208.1 - 0.0068 16.0 3.1 0.0068 16.0 3.1 4.3 1 1 2 4 4 4 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Bacillus_HBL PF05791.11 EMR62208.1 - 0.084 12.7 16.6 0.16 11.8 1.7 3.3 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) GhoS PF11080.8 EMR62208.1 - 0.21 11.6 1.2 0.49 10.4 0.1 2.1 2 0 0 2 2 2 0 Endoribonuclease GhoS DUF2252 PF10009.9 EMR62208.1 - 3.9 6.4 19.6 0.22 10.5 7.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF3287 PF11690.8 EMR62208.1 - 4.6 7.0 18.9 4.9 6.9 5.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) VPS11_C PF12451.8 EMR62208.1 - 4.6 7.6 8.8 20 5.5 0.4 4.0 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal Filament PF00038.21 EMR62208.1 - 5.7 6.4 46.4 11 5.4 46.4 1.8 1 1 0 1 1 1 0 Intermediate filament protein Syntaxin-6_N PF09177.11 EMR62208.1 - 8.9 6.9 29.6 0.92 10.1 0.6 3.6 2 2 1 3 3 3 0 Syntaxin 6, N-terminal WSC PF01822.19 EMR62209.1 - 5.5e-09 36.1 11.4 3.7e-06 27.0 6.2 2.4 1 1 1 2 2 2 2 WSC domain Cytomega_UL20A PF05984.12 EMR62209.1 - 0.045 14.1 0.2 0.13 12.6 0.2 1.7 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein MFS_1 PF07690.16 EMR62210.1 - 1.5e-35 122.7 81.6 1.7e-26 93.0 48.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 EMR62210.1 - 0.27 10.7 2.3 1.2 8.6 2.3 2.1 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Sod_Fe_C PF02777.18 EMR62211.1 - 1.4e-14 54.1 0.0 1.3e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMR62211.1 - 0.0028 18.1 0.0 0.0043 17.5 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain IU_nuc_hydro PF01156.19 EMR62212.1 - 4e-78 263.1 0.0 4.7e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Aminotran_3 PF00202.21 EMR62213.1 - 2.7e-67 227.2 0.0 2.9e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NUC130_3NT PF08158.12 EMR62213.1 - 0.032 14.5 0.2 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 NUC130/3NT domain Gag_p24 PF00607.20 EMR62213.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Exo70 PF03081.15 EMR62214.1 - 3.4e-90 302.8 0.1 5.7e-90 302.1 0.1 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.12 EMR62214.1 - 0.00018 21.5 5.8 0.04 14.0 0.3 3.5 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus MukF_M PF17192.4 EMR62214.1 - 0.0033 17.2 0.4 0.3 10.8 0.0 3.1 2 1 1 3 3 3 1 MukF middle domain Apolipoprotein PF01442.18 EMR62214.1 - 0.02 14.8 3.4 0.045 13.6 0.2 2.8 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 EMR62214.1 - 3.8 7.7 5.1 21 5.3 0.0 3.8 4 1 0 4 4 4 0 Fibrinogen alpha/beta chain family RED_N PF07808.13 EMR62215.1 - 8e-07 28.9 12.4 8e-07 28.9 12.4 2.3 2 1 0 2 2 2 1 RED-like protein N-terminal region GvpG PF05120.12 EMR62215.1 - 7.2 6.7 7.7 0.38 10.8 0.9 2.3 2 0 0 2 2 2 0 Gas vesicle protein G NmrA PF05368.13 EMR62216.1 - 5.2e-12 45.8 0.0 6.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR62216.1 - 5.8e-08 32.8 0.0 1.7e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding ABC_tran PF00005.27 EMR62218.1 - 1.4e-51 174.6 0.1 7.4e-29 101.0 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR62218.1 - 6.3e-42 144.1 11.5 6.3e-42 144.1 11.5 3.7 3 1 1 4 4 4 1 ABC transporter transmembrane region SMC_N PF02463.19 EMR62218.1 - 1.1e-09 38.1 4.2 0.0021 17.5 0.1 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMR62218.1 - 9.9e-06 25.6 0.2 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMR62218.1 - 3.9e-05 23.7 0.9 0.43 10.7 0.3 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EMR62218.1 - 0.0003 21.2 0.9 1.1 9.6 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EMR62218.1 - 0.0033 17.1 0.5 2.6 7.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 EMR62218.1 - 0.0053 16.8 0.1 0.89 9.6 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_5 PF07728.14 EMR62218.1 - 0.014 15.4 0.0 23 5.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMR62218.1 - 0.036 14.3 2.4 5.6 7.2 0.1 3.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EMR62218.1 - 0.038 13.9 0.5 0.3 11.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EMR62218.1 - 0.04 14.4 1.0 6.8 7.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain MWFE PF15879.5 EMR62218.1 - 0.091 12.9 0.2 0.091 12.9 0.2 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit RNA_helicase PF00910.22 EMR62218.1 - 0.12 12.8 0.0 7.1 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 EMR62218.1 - 0.12 12.5 4.5 0.54 10.3 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_7 PF12775.7 EMR62218.1 - 0.12 11.9 0.2 20 4.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 EMR62218.1 - 0.15 11.3 0.4 6.9 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 EMR62218.1 - 0.15 11.7 1.7 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 EMR62218.1 - 0.17 11.2 0.9 6 6.1 0.0 2.4 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 EMR62218.1 - 0.19 12.0 1.2 47 4.2 0.1 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EMR62218.1 - 0.47 10.1 2.0 5.4 6.7 0.0 3.2 4 0 0 4 4 4 0 AAA domain MFS_1 PF07690.16 EMR62219.1 - 3e-18 65.9 10.5 5.3e-11 42.0 1.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Cullin PF00888.22 EMR62220.1 - 4.2e-179 597.1 0.2 5.1e-179 596.8 0.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EMR62220.1 - 5.9e-19 67.9 3.6 2.5e-17 62.7 0.9 2.6 2 0 0 2 2 2 2 Cullin protein neddylation domain DRAT PF07357.11 EMR62220.1 - 0.16 11.1 1.2 5.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Zeta_toxin PF06414.12 EMR62221.1 - 1.8e-36 125.3 0.0 4.6e-36 124.0 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EMR62221.1 - 0.024 15.0 0.0 0.068 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 EMR62221.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain p450 PF00067.22 EMR62222.1 - 3.3e-14 52.5 0.0 5.9e-14 51.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Clr5 PF14420.6 EMR62223.1 - 5.2e-17 61.8 6.0 9.2e-17 61.0 6.0 1.4 1 0 0 1 1 1 1 Clr5 domain AA_permease_2 PF13520.6 EMR62224.1 - 4.1e-41 141.2 47.7 4.7e-41 141.0 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR62224.1 - 1.3e-18 66.9 36.4 2e-18 66.2 36.4 1.2 1 0 0 1 1 1 1 Amino acid permease PfkB PF00294.24 EMR62225.1 - 1.3e-42 146.1 0.1 1.6e-42 145.8 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ank_2 PF12796.7 EMR62226.1 - 8.7e-49 164.0 0.3 1.7e-11 44.6 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EMR62226.1 - 6.8e-38 127.5 1.0 7.4e-06 26.2 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EMR62226.1 - 4.3e-35 115.8 0.4 0.00064 20.0 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EMR62226.1 - 6e-33 112.8 1.4 2.7e-08 34.2 0.1 5.9 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR62226.1 - 1.1e-24 86.1 7.9 2.3e-05 24.6 0.1 6.7 3 1 4 7 7 7 6 Ankyrin repeats (many copies) PEGA PF08308.11 EMR62226.1 - 0.012 15.5 0.0 1.6 8.7 0.0 2.9 2 0 0 2 2 2 0 PEGA domain Abhydrolase_1 PF00561.20 EMR62227.1 - 2.6e-32 112.5 0.1 3.1e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR62227.1 - 4.5e-14 52.3 0.0 2.3e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR62227.1 - 1.8e-08 35.3 0.1 2.9e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EMR62227.1 - 0.00019 21.0 0.0 0.048 13.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.14 EMR62227.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Ndr PF03096.14 EMR62227.1 - 0.017 13.8 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Peptidase_S15 PF02129.18 EMR62227.1 - 0.019 14.6 0.6 0.051 13.2 0.6 1.8 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.12 EMR62227.1 - 0.064 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 HET PF06985.11 EMR62228.1 - 2.5e-23 83.0 0.0 3.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PgaD PF13994.6 EMR62228.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein bZIP_1 PF00170.21 EMR62230.1 - 0.00041 20.4 6.2 0.00069 19.7 6.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMR62230.1 - 0.0065 16.5 6.9 0.01 15.9 6.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Methyltransf_23 PF13489.6 EMR62231.1 - 3.3e-20 72.6 0.0 4.2e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR62231.1 - 2.2e-13 50.7 0.0 6.1e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR62231.1 - 3.8e-13 49.5 0.0 2.6e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR62231.1 - 2.2e-11 44.3 0.0 4.6e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR62231.1 - 2.9e-11 44.0 0.0 2.9e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EMR62231.1 - 5e-06 26.4 0.0 7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 EMR62231.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EMR62231.1 - 0.00036 20.1 0.0 0.0015 18.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EMR62231.1 - 0.00063 19.9 0.0 0.0015 18.7 0.0 1.6 1 1 0 2 2 2 1 FtsJ-like methyltransferase CheR PF01739.18 EMR62231.1 - 0.00094 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 EMR62231.1 - 0.0063 15.9 0.0 0.068 12.5 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMR62231.1 - 0.0065 15.8 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Crr6 PF08847.11 EMR62231.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Chlororespiratory reduction 6 DUF938 PF06080.12 EMR62231.1 - 0.068 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 EMR62231.1 - 0.13 11.5 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain Na_H_Exchanger PF00999.21 EMR62232.1 - 9e-52 176.1 37.1 8.6e-29 100.5 14.5 2.2 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Glyco_transf_41 PF13844.6 EMR62233.1 - 2.8e-87 293.2 0.0 5.3e-49 166.9 0.0 3.2 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EMR62233.1 - 1e-18 66.3 0.0 0.00076 19.2 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EMR62233.1 - 4.7e-15 54.4 0.0 0.19 11.9 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EMR62233.1 - 2.1e-12 46.5 1.4 0.09 12.7 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMR62233.1 - 3.5e-12 45.8 0.0 0.013 15.1 0.0 6.3 3 2 3 6 6 6 2 TPR repeat TPR_12 PF13424.6 EMR62233.1 - 5.8e-12 45.7 0.7 0.089 13.1 0.0 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMR62233.1 - 9.6e-12 44.1 0.2 0.0031 17.6 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMR62233.1 - 1e-09 38.1 0.0 0.054 13.9 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMR62233.1 - 1.2e-08 35.1 4.4 0.34 11.8 0.0 6.3 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMR62233.1 - 4.2e-06 27.2 0.5 5.9 7.5 0.0 4.9 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMR62233.1 - 0.00011 22.0 0.4 1.2 9.3 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMR62233.1 - 0.00075 20.1 0.0 18 6.1 0.0 4.8 3 2 1 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EMR62233.1 - 0.00086 19.8 0.4 0.58 10.6 0.0 3.1 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 EMR62233.1 - 0.043 13.9 0.4 3.5 7.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR62233.1 - 0.047 13.9 0.1 1.7 8.9 0.0 2.9 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Myb_DNA-binding PF00249.31 EMR62234.1 - 1.4e-24 86.0 1.7 1.9e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR62234.1 - 3.5e-17 62.4 3.2 3.9e-10 39.8 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 EMR62234.1 - 0.0017 18.1 0.2 0.36 10.7 0.0 3.1 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 EMR62234.1 - 0.015 15.1 0.6 0.14 12.0 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Zip PF02535.22 EMR62234.1 - 1.2 8.3 6.9 1.3 8.1 6.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.16 EMR62234.1 - 3.2 7.0 5.7 4.2 6.6 5.7 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Sec23_trunk PF04811.15 EMR62235.1 - 1.7e-79 266.9 0.0 2.3e-79 266.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EMR62235.1 - 3.1e-30 104.8 0.2 6.3e-30 103.8 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EMR62235.1 - 1.5e-25 89.0 0.1 4.6e-25 87.4 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EMR62235.1 - 1.2e-15 57.3 6.5 2.2e-15 56.4 6.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EMR62235.1 - 9.8e-13 47.8 0.0 2.6e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EMR62235.1 - 0.047 13.1 0.9 0.11 11.9 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L11_N PF03946.14 EMR62236.1 - 2.7e-25 88.0 0.2 4.4e-25 87.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EMR62236.1 - 2.4e-15 56.8 0.1 4.2e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Tfb2 PF03849.14 EMR62237.1 - 2.6e-90 303.0 0.0 2.9e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 IBN_N PF03810.19 EMR62240.1 - 3.2e-05 23.7 0.0 0.00016 21.5 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EMR62240.1 - 0.014 15.5 1.7 0.066 13.3 0.0 3.0 5 0 0 5 5 5 0 Exportin 1-like protein Cse1 PF08506.10 EMR62240.1 - 0.031 13.1 0.2 0.061 12.1 0.2 1.4 1 0 0 1 1 1 0 Cse1 SKA2 PF16740.5 EMR62240.1 - 0.078 12.8 0.5 0.22 11.3 0.5 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Pex2_Pex12 PF04757.14 EMR62241.1 - 5.8e-36 124.2 0.3 8.8e-36 123.6 0.3 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EMR62241.1 - 0.043 14.0 4.1 0.09 13.0 4.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EMR62241.1 - 9.2 6.2 9.9 14 5.6 5.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1b PF00579.25 EMR62242.1 - 6.7e-75 252.1 0.0 9.2e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EMR62242.1 - 7.7e-44 148.4 0.0 1.6e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain NPR2 PF06218.11 EMR62244.1 - 9.9e-125 416.7 0.0 1.5e-124 416.1 0.0 1.3 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Ribosomal_60s PF00428.19 EMR62244.1 - 0.084 13.5 6.6 0.18 12.4 6.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein SelP_N PF04592.14 EMR62244.1 - 4.6 6.6 6.0 7.8 5.8 6.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CybS PF05328.12 EMR62245.1 - 1.1e-51 174.0 0.0 1.5e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Vps53_N PF04100.12 EMR62246.1 - 3.8e-101 338.8 0.0 5.9e-101 338.2 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal RINT1_TIP1 PF04437.13 EMR62246.1 - 4.5e-06 25.8 0.2 0.018 13.9 0.0 3.0 3 0 0 3 3 3 2 RINT-1 / TIP-1 family Vps54_N PF10475.9 EMR62246.1 - 1.8e-05 24.2 0.4 3.6e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EMR62246.1 - 0.00011 22.1 0.2 0.0002 21.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.11 EMR62246.1 - 0.0062 15.5 0.8 0.012 14.5 0.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Fungal_trans PF04082.18 EMR62247.1 - 1.3e-14 53.9 1.0 2.9e-14 52.7 0.1 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Na_H_Exchanger PF00999.21 EMR62248.1 - 2.1e-33 115.7 18.2 2.6e-33 115.3 18.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EMR62248.1 - 0.0045 17.1 0.2 0.0045 17.1 0.2 3.1 3 1 0 3 3 3 1 YrhC-like protein MFS_1 PF07690.16 EMR62249.1 - 4.5e-39 134.4 28.1 5.4e-39 134.1 28.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.9 EMR62249.1 - 0.1 12.8 1.3 0.16 12.2 0.1 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1772 PF08592.11 EMR62249.1 - 0.53 10.6 17.1 1.5 9.2 5.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) CRAL_TRIO PF00650.20 EMR62251.1 - 1.9e-07 30.9 0.7 1.9e-06 27.7 0.7 2.1 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMR62251.1 - 3.2e-05 24.0 0.0 7.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Colicin_im PF03857.13 EMR62252.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Colicin immunity protein Glyco_hydro_18 PF00704.28 EMR62253.1 - 8.3e-40 137.4 0.0 1e-39 137.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 EMR62254.1 - 1.8e-36 125.8 25.7 2.2e-36 125.5 25.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR62254.1 - 1.2e-12 47.5 14.4 2.8e-11 43.0 14.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EMR62254.1 - 1e-09 37.4 0.5 1.5e-09 36.8 0.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.6 EMR62254.1 - 0.043 14.3 0.7 0.43 11.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) RPAP1_N PF08621.10 EMR62254.1 - 0.23 11.2 0.5 0.52 10.1 0.5 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal OATP PF03137.20 EMR62254.1 - 0.35 9.1 5.9 0.78 7.9 4.8 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SET PF00856.28 EMR62255.1 - 1.1e-13 52.0 0.0 5.9e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EMR62255.1 - 3.1e-07 30.4 14.5 3.1e-07 30.4 14.5 2.6 2 1 0 2 2 2 1 MYND finger Aldo_ket_red PF00248.21 EMR62256.1 - 1.6e-40 139.2 0.0 2.4e-39 135.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family FAA_hydrolase PF01557.18 EMR62257.1 - 1.3e-60 204.7 0.0 1.6e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aldedh PF00171.22 EMR62258.1 - 1.8e-152 508.1 0.5 2e-152 507.9 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF423 PF04241.15 EMR62259.1 - 1.6e-25 89.1 1.5 1.6e-25 89.1 1.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF423) NADH-u_ox-rdase PF10785.9 EMR62259.1 - 0.0045 17.6 0.6 0.0081 16.8 0.1 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit AAA PF00004.29 EMR62261.1 - 4.8e-50 169.4 0.0 2.4e-38 131.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR62261.1 - 6.2e-09 36.5 0.1 0.0082 16.5 0.0 3.2 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EMR62261.1 - 4e-08 33.6 0.1 0.00068 19.9 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 EMR62261.1 - 1.3e-07 31.3 0.0 3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 EMR62261.1 - 6.7e-07 28.8 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EMR62261.1 - 7.8e-07 29.2 0.0 0.0081 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EMR62261.1 - 2e-06 28.0 0.0 2.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EMR62261.1 - 6.9e-06 25.9 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 EMR62261.1 - 1.7e-05 24.5 0.0 0.0003 20.5 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 EMR62261.1 - 1.8e-05 24.7 0.0 0.0016 18.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMR62261.1 - 2.7e-05 23.6 0.1 0.0037 16.7 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EMR62261.1 - 4.2e-05 23.3 0.1 0.027 14.2 0.1 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EMR62261.1 - 4.3e-05 24.1 0.0 0.012 16.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMR62261.1 - 6.1e-05 23.2 0.0 0.39 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EMR62261.1 - 0.00018 21.3 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 EMR62261.1 - 0.0002 20.9 0.3 0.025 14.1 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EMR62261.1 - 0.00028 21.2 0.0 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase PF06745.13 EMR62261.1 - 0.00036 20.0 0.2 0.0062 15.9 0.1 2.4 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.26 EMR62261.1 - 0.00047 19.9 0.0 0.6 9.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 EMR62261.1 - 0.00073 19.5 0.1 1.8 8.4 0.0 3.2 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea TsaE PF02367.17 EMR62261.1 - 0.00091 19.2 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EMR62261.1 - 0.0018 17.5 0.1 2.3 7.3 0.1 2.5 2 0 0 2 2 2 2 NB-ARC domain CDC48_N PF02359.18 EMR62261.1 - 0.0028 17.8 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain ABC_tran PF00005.27 EMR62261.1 - 0.0046 17.5 0.5 0.12 12.9 0.1 2.4 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 EMR62261.1 - 0.0079 16.1 2.0 2.8 7.8 0.0 3.0 4 0 0 4 4 3 1 NACHT domain PhoH PF02562.16 EMR62261.1 - 0.0092 15.5 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 EMR62261.1 - 0.0096 15.5 0.7 2.7 7.5 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EMR62261.1 - 0.017 14.8 0.1 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EMR62261.1 - 0.034 13.9 0.0 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMR62261.1 - 0.038 14.2 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EMR62261.1 - 0.047 12.9 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 EMR62261.1 - 0.1 12.4 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EMR62261.1 - 0.11 12.8 0.3 0.69 10.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EMR62261.1 - 0.12 11.8 0.0 12 5.3 0.0 3.1 2 1 0 3 3 3 0 Bacterial TniB protein Docking PF08990.11 EMR62261.1 - 0.19 11.4 0.1 0.45 10.2 0.1 1.6 1 0 0 1 1 1 0 Erythronolide synthase docking Parvo_NS1 PF01057.17 EMR62261.1 - 0.23 10.5 0.1 0.49 9.4 0.0 1.5 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 Sugar_tr PF00083.24 EMR62262.1 - 1.4e-22 80.2 19.2 2.2e-15 56.5 0.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR62262.1 - 9.6e-13 47.8 26.8 1.3e-10 40.7 3.7 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily Folate_carrier PF01770.18 EMR62262.1 - 0.013 14.3 4.8 0.023 13.5 4.8 1.3 1 0 0 1 1 1 0 Reduced folate carrier TFIIA PF03153.13 EMR62264.1 - 0.00012 22.2 4.6 0.00015 21.9 4.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RNase_PH PF01138.21 EMR62264.1 - 0.00055 20.4 0.0 0.0016 19.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 DUF908 PF06012.12 EMR62264.1 - 0.0015 18.1 0.8 0.0019 17.7 0.8 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF2722 PF10846.8 EMR62264.1 - 0.0019 17.2 11.8 0.0019 17.2 11.8 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) RNase_PH_C PF03725.15 EMR62264.1 - 0.0044 17.0 0.2 0.0082 16.2 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 UPF0560 PF10577.9 EMR62264.1 - 0.016 13.8 2.1 0.02 13.4 2.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ilar_coat PF01787.16 EMR62264.1 - 0.016 15.0 1.4 0.023 14.5 1.4 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein PEARLI-4 PF05278.12 EMR62264.1 - 0.021 14.4 0.6 0.032 13.8 0.6 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Suf PF05843.14 EMR62264.1 - 0.025 14.6 4.4 0.034 14.1 4.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Androgen_recep PF02166.16 EMR62264.1 - 0.037 12.9 10.9 0.052 12.4 10.9 1.2 1 0 0 1 1 1 0 Androgen receptor CagX PF03524.15 EMR62264.1 - 0.039 13.7 0.6 0.048 13.4 0.6 1.2 1 0 0 1 1 1 0 Conjugal transfer protein Spt20 PF12090.8 EMR62264.1 - 0.044 13.4 18.2 0.063 12.9 18.2 1.1 1 0 0 1 1 1 0 Spt20 family Hydin_ADK PF17213.3 EMR62264.1 - 0.12 12.7 1.7 0.18 12.0 1.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PRIMA1 PF16101.5 EMR62264.1 - 0.15 12.1 2.8 0.31 11.1 2.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 OATP PF03137.20 EMR62264.1 - 0.16 10.2 0.9 0.21 9.9 0.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Presenilin PF01080.17 EMR62264.1 - 0.21 10.3 0.6 0.23 10.2 0.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 EMR62264.1 - 2.6 9.1 7.1 4.7 8.2 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) P_C PF06640.11 EMR62264.1 - 2.7 8.1 10.2 13 5.8 4.2 2.5 2 0 0 2 2 2 0 P protein C-terminus DUF3464 PF11947.8 EMR62264.1 - 3.5 7.4 5.3 5.9 6.6 5.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Methyltransf_23 PF13489.6 EMR62265.1 - 2.7e-10 40.3 0.0 3.5e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR62265.1 - 1e-09 38.9 0.0 1.5e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR62265.1 - 2e-07 31.6 0.0 3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR62265.1 - 3.4e-07 30.2 0.0 7.1e-07 29.1 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR62265.1 - 4e-06 27.4 0.0 5.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EMR62265.1 - 0.0073 15.3 0.0 0.0092 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Myb_DNA-bind_6 PF13921.6 EMR62266.1 - 1.2e-07 31.9 0.0 2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMR62266.1 - 4e-05 23.7 0.4 6.9e-05 23.0 0.4 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain PBP1_TM PF14812.6 EMR62266.1 - 0.0036 17.6 4.4 0.0036 17.6 4.4 2.1 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal IFT57 PF10498.9 EMR62266.1 - 0.012 14.6 1.6 0.015 14.3 1.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Myb_DNA-bind_4 PF13837.6 EMR62266.1 - 0.014 15.7 0.2 0.027 14.9 0.2 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Goodbye PF17109.5 EMR62267.1 - 1.8e-18 67.1 0.0 1.1e-17 64.5 0.0 2.5 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 EMR62267.1 - 0.063 13.6 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.6 EMR62267.1 - 0.098 13.5 2.2 8.8 7.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Pro-rich_19 PF15455.6 EMR62267.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Proline-rich 19 SapB_1 PF05184.15 EMR62267.1 - 1.5 8.9 4.2 9 6.4 0.0 3.9 4 0 0 4 4 4 0 Saposin-like type B, region 1 DUF924 PF06041.11 EMR62268.1 - 4e-14 53.1 0.0 6.9e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) p450 PF00067.22 EMR62269.1 - 2.9e-23 82.3 0.0 3.3e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 EMR62270.1 - 1.6e-26 93.0 0.0 2.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EMR62270.1 - 0.025 14.4 0.1 0.15 11.8 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Dimerisation PF08100.11 EMR62270.1 - 0.059 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Dimerisation domain MFS_1 PF07690.16 EMR62271.1 - 7.4e-13 48.1 50.4 5.3e-09 35.5 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PUL PF08324.11 EMR62272.1 - 1.3e-59 201.7 0.0 1.8e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EMR62272.1 - 1.7e-42 144.2 0.8 3e-42 143.4 0.8 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EMR62272.1 - 2e-29 101.2 10.3 5.1e-06 27.1 0.0 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat Imm51 PF15595.6 EMR62272.1 - 0.047 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 51 BBS2_Mid PF14783.6 EMR62272.1 - 0.081 13.0 0.0 53 3.9 0.0 4.0 3 1 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 EMR62273.1 - 3.1e-20 72.1 9.5 7.8e-09 36.0 0.1 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR62273.1 - 1e-05 25.7 0.1 0.16 12.3 0.0 4.4 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR62273.1 - 6.3e-05 22.1 0.0 0.045 12.7 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SRR1 PF07985.12 EMR62276.1 - 3.4e-15 55.8 0.1 5.5e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 SRR1 Oxidored_FMN PF00724.20 EMR62277.1 - 2.1e-31 109.5 0.0 2.5e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EMR62277.1 - 0.052 13.0 0.4 12 5.3 0.0 3.2 3 1 0 3 3 3 0 Xylose isomerase-like TIM barrel Aa_trans PF01490.18 EMR62278.1 - 2.2e-26 92.5 35.8 3.1e-26 92.0 35.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNase_T PF00929.24 EMR62280.1 - 3e-19 70.1 0.0 3.9e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Rhomboid PF01694.22 EMR62281.1 - 6.2e-08 32.8 0.6 6.2e-08 32.8 0.6 1.5 2 0 0 2 2 2 1 Rhomboid family 2-Hacid_dh_C PF02826.19 EMR62283.1 - 3e-36 124.4 0.0 2.8e-22 78.9 0.0 2.8 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EMR62283.1 - 0.032 14.8 0.0 0.059 14.0 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh PF00389.30 EMR62283.1 - 0.034 13.8 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Gp_dh_N PF00044.24 EMR62283.1 - 0.061 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Nmad5 PF18757.1 EMR62284.1 - 0.0033 17.7 2.8 0.0063 16.8 2.8 1.4 1 1 0 1 1 1 1 Nucleotide modification associated domain 5 TolA_bind_tri PF16331.5 EMR62284.1 - 0.0075 16.3 0.9 0.04 14.0 0.1 2.3 1 1 1 2 2 2 1 TolA binding protein trimerisation Vps54_N PF10475.9 EMR62284.1 - 0.018 14.4 0.4 0.034 13.4 0.4 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DUF1664 PF07889.12 EMR62284.1 - 0.042 13.9 0.5 0.097 12.7 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 EMR62284.1 - 0.087 12.8 11.7 0.7 9.9 6.6 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4025 PF13217.6 EMR62284.1 - 0.11 12.3 0.2 0.32 10.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4025) ATG16 PF08614.11 EMR62284.1 - 0.17 12.1 13.6 0.068 13.4 9.7 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EMR62284.1 - 0.45 11.0 11.4 0.098 13.2 7.2 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region TSC22 PF01166.18 EMR62284.1 - 8.5 6.8 7.5 9.8 6.6 1.4 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family HSP70 PF00012.20 EMR62285.1 - 5.8e-06 24.8 0.0 2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein Cupin_5 PF06172.11 EMR62287.1 - 1.9e-33 115.6 0.1 2.6e-33 115.2 0.1 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) PEP_hydrolase PF09370.10 EMR62288.1 - 2.1e-130 433.7 0.0 2.4e-130 433.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 EMR62288.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Radical_SAM PF04055.21 EMR62288.1 - 0.0052 17.2 0.0 0.082 13.3 0.0 2.4 2 1 1 3 3 3 1 Radical SAM superfamily AP_endonuc_2 PF01261.24 EMR62288.1 - 0.22 10.9 0.5 0.62 9.5 0.2 1.9 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Zn_clus PF00172.18 EMR62289.1 - 4.5 7.5 9.6 3.5 7.8 0.6 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MAPEG PF01124.18 EMR62290.1 - 4.4e-22 78.4 0.1 5.1e-22 78.2 0.1 1.0 1 0 0 1 1 1 1 MAPEG family Aminotran_3 PF00202.21 EMR62291.1 - 6.9e-122 407.0 0.0 8e-122 406.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EMR62291.1 - 0.00095 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMR62291.1 - 0.0032 16.7 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II COesterase PF00135.28 EMR62292.1 - 1.4e-47 162.8 0.0 1.7e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR62292.1 - 5e-06 26.5 0.7 4.1e-05 23.5 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1771 PF08590.10 EMR62293.1 - 9e-16 58.0 11.6 1.4e-15 57.4 11.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EMR62293.1 - 3.5e-07 30.5 0.0 9.5e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Smr domain GH131_N PF18271.1 EMR62294.1 - 1.9e-57 194.9 1.0 2.2e-57 194.7 1.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain UPF0261 PF06792.11 EMR62296.1 - 7.2e-140 466.5 3.7 5.6e-115 384.5 0.7 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0261) CoA_trans PF01144.23 EMR62296.1 - 0.0094 15.4 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Coenzyme A transferase Abhydrolase_1 PF00561.20 EMR62297.1 - 7.2e-09 35.7 0.0 2.3e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR62297.1 - 1.8e-05 24.2 0.0 3.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMR62297.1 - 0.12 11.8 0.0 0.95 8.9 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family DEAD PF00270.29 EMR62298.1 - 5.8e-28 97.8 0.0 9e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR62298.1 - 1.6e-19 70.3 0.0 1.5e-18 67.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR62298.1 - 0.00032 20.7 0.0 0.00089 19.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNARE_assoc PF09335.11 EMR62300.1 - 2.7e-15 56.9 7.9 2.7e-15 56.9 7.9 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein DEAD PF00270.29 EMR62301.1 - 2.3e-45 154.5 1.2 3.6e-45 153.9 1.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR62301.1 - 6.7e-32 110.1 0.2 1.7e-30 105.6 0.0 2.8 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR62301.1 - 4.3e-06 26.9 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMR62301.1 - 0.00059 19.6 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR62301.1 - 0.0016 18.7 0.9 0.0091 16.3 0.4 2.2 2 1 0 2 2 2 1 AAA domain IL17R_D_N PF16742.5 EMR62301.1 - 0.0071 16.4 0.1 0.025 14.6 0.0 1.9 2 0 0 2 2 2 1 N-terminus of interleukin 17 receptor D AAA_22 PF13401.6 EMR62301.1 - 0.013 15.8 0.3 0.051 13.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 EMR62301.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit fragilysinNterm PF16376.5 EMR62301.1 - 0.09 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 EMR62301.1 - 0.093 12.7 0.1 0.41 10.6 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 EMR62301.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Helicase Pkinase PF00069.25 EMR62302.1 - 2.3e-31 109.1 0.0 2.7e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR62302.1 - 5e-23 81.7 0.0 5.9e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMR62302.1 - 0.0028 17.6 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EMR62302.1 - 0.032 13.6 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Na_H_Exchanger PF00999.21 EMR62303.1 - 3e-73 246.8 30.3 3.6e-73 246.6 30.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 EMR62303.1 - 0.032 13.9 0.5 0.032 13.9 0.5 2.2 2 0 0 2 2 2 0 PepSY-associated TM region TIP41 PF04176.13 EMR62304.1 - 7.6e-63 211.1 0.0 1.9e-62 209.8 0.0 1.6 1 1 0 1 1 1 1 TIP41-like family Tudor_1_RapA PF18339.1 EMR62304.1 - 0.18 11.8 0.6 0.37 10.8 0.6 1.4 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain 1 HBS1_N PF08938.10 EMR62305.1 - 0.0018 18.6 0.2 0.0047 17.2 0.0 1.7 2 0 0 2 2 2 1 HBS1 N-terminus zf-CCCH PF00642.24 EMR62305.1 - 0.002 18.0 0.3 0.0033 17.3 0.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EMR62305.1 - 0.045 14.2 0.5 0.069 13.6 0.5 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 EMR62305.1 - 0.06 13.4 1.7 0.32 11.1 1.7 2.0 1 1 0 1 1 1 0 Zinc finger domain CUE PF02845.16 EMR62305.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 CUE domain zf-CCCH_4 PF18044.1 EMR62305.1 - 1.1 9.2 4.4 15 5.5 4.4 2.2 1 1 0 1 1 1 0 CCCH-type zinc finger FMN_dh PF01070.18 EMR62306.1 - 1e-111 373.3 0.0 1.4e-111 372.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EMR62306.1 - 1.3e-17 63.7 0.1 3.1e-17 62.5 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 EMR62306.1 - 4.9e-05 22.5 1.3 0.0021 17.1 0.1 3.0 1 1 2 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMR62306.1 - 0.00012 21.6 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 EMR62306.1 - 0.00014 21.3 0.1 0.11 11.7 0.0 2.2 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 EMR62306.1 - 0.00082 18.6 0.2 0.0012 18.0 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EMR62306.1 - 0.011 15.2 0.3 1 8.8 0.1 2.4 1 1 1 2 2 2 0 Histidine biosynthesis protein Dus PF01207.17 EMR62306.1 - 0.1 11.7 0.1 0.61 9.1 0.0 2.2 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) RhoGAP PF00620.27 EMR62307.1 - 4.2e-35 120.8 0.0 6.8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Anophelin PF10731.9 EMR62308.1 - 0.002 17.9 0.2 0.0091 15.8 0.2 2.2 1 0 0 1 1 1 1 Thrombin inhibitor from mosquito FAM76 PF16046.5 EMR62308.1 - 5.7 6.2 9.6 8.1 5.7 0.7 2.1 2 0 0 2 2 2 0 FAM76 protein CsbD PF05532.12 EMR62309.1 - 7.8e-06 25.7 8.1 0.009 15.9 0.5 2.3 1 1 1 2 2 2 2 CsbD-like DUF4438 PF14505.6 EMR62309.1 - 0.26 10.2 1.9 0.33 9.9 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4438) DnaJ_C PF01556.18 EMR62311.1 - 2.2e-38 131.6 0.1 3e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMR62311.1 - 1e-25 89.6 0.3 1.7e-25 88.9 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMR62311.1 - 2.5e-16 59.8 18.0 4.2e-16 59.1 18.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EMR62311.1 - 0.02 14.9 18.1 0.26 11.3 3.9 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EMR62311.1 - 0.025 14.6 9.4 0.4 10.7 2.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_C74 PF12387.8 EMR62311.1 - 0.12 11.8 0.7 0.21 11.0 0.7 1.3 1 0 0 1 1 1 0 Pestivirus NS2 peptidase CAAX_1 PF15895.5 EMR62311.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 CAAX box cerebral protein 1 zinc-ribbons_6 PF07191.12 EMR62311.1 - 1.2 9.2 6.6 3.4 7.7 1.1 2.3 1 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 EMR62311.1 - 1.6 8.8 9.7 6.1 7.0 1.2 2.3 1 1 2 3 3 3 0 Double zinc ribbon Ank_3 PF13606.6 EMR62312.1 - 2.7e-16 58.0 0.0 0.00015 21.9 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 EMR62312.1 - 2.1e-15 56.3 0.4 0.00029 21.2 0.0 7.5 7 1 0 7 7 7 3 Ankyrin repeat Ank_2 PF12796.7 EMR62312.1 - 1.8e-14 54.1 0.0 0.00035 21.1 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR62312.1 - 1.7e-13 50.8 0.1 0.0068 17.0 0.0 6.0 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR62312.1 - 1.3e-10 41.3 0.5 0.017 15.4 0.0 5.2 5 1 0 5 5 5 2 Ankyrin repeats (many copies) F-box PF00646.33 EMR62312.1 - 2e-05 24.3 0.4 6.3e-05 22.7 0.4 1.9 1 0 0 1 1 1 1 F-box domain DUF5449 PF17528.2 EMR62312.1 - 0.036 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5449) BCNT PF07572.12 EMR62313.1 - 3.2e-25 88.0 3.9 7e-25 86.9 3.9 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development Mucin PF01456.17 EMR62313.1 - 2.6 8.0 8.3 1.1 9.3 5.7 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3543 PF12063.8 EMR62314.1 - 2.6e-93 312.0 0.3 4e-93 311.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EMR62314.1 - 1.1e-62 211.8 0.0 1.9e-62 211.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR62314.1 - 3.5e-42 144.5 0.0 7.1e-42 143.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 EMR62314.1 - 0.011 15.9 0.3 0.039 14.1 0.1 2.0 2 0 0 2 2 2 0 ABC1 family Pox_ser-thr_kin PF05445.11 EMR62314.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.22 EMR62315.1 - 9e-57 192.8 0.0 3.2e-56 191.0 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 AAA PF00004.29 EMR62316.1 - 6.9e-18 65.3 0.0 1.4e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMR62316.1 - 9.7e-06 25.9 0.1 0.00028 21.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EMR62316.1 - 0.00047 20.6 0.1 0.0017 18.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EMR62316.1 - 0.0016 18.5 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EMR62316.1 - 0.029 14.5 0.0 0.08 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMR62316.1 - 0.031 14.8 0.0 0.1 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EMR62316.1 - 0.05 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EMR62316.1 - 0.051 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 EMR62316.1 - 0.059 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4611 PF15387.6 EMR62316.1 - 0.81 9.9 5.8 13 6.1 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) ATPase PF06745.13 EMR62316.1 - 1 8.6 2.5 1.6 8.0 0.4 2.3 3 0 0 3 3 3 0 KaiC MAPEG PF01124.18 EMR62317.1 - 5.6e-17 61.9 3.0 6.5e-17 61.7 3.0 1.1 1 0 0 1 1 1 1 MAPEG family BTP PF05232.12 EMR62317.1 - 2 8.5 6.8 0.55 10.3 1.5 2.2 2 0 0 2 2 2 0 Chlorhexidine efflux transporter RicinB_lectin_2 PF14200.6 EMR62319.1 - 1.1e-16 61.3 7.4 2.4e-12 47.4 0.5 2.7 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Inhibitor_I48 PF10467.9 EMR62319.1 - 0.0013 18.6 0.1 0.0017 18.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor clitocypin Inhibitor_I66 PF16850.5 EMR62319.1 - 0.0036 17.2 0.1 0.0067 16.3 0.1 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I66 Acyl_transf_1 PF00698.21 EMR62320.1 - 5.1e-19 68.9 0.0 1e-10 41.7 0.0 2.0 1 1 1 2 2 2 2 Acyl transferase domain DUF915 PF06028.11 EMR62320.1 - 0.077 12.3 0.0 0.24 10.7 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) F-box-like PF12937.7 EMR62321.1 - 3.7e-05 23.5 0.0 0.0001 22.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like FAD_binding_2 PF00890.24 EMR62322.1 - 9.9e-41 140.2 1.2 1.8e-40 139.3 1.2 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EMR62322.1 - 9.4e-08 31.8 0.1 1.9e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EMR62322.1 - 1.8e-07 31.1 8.1 2.7e-07 30.5 1.6 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR62322.1 - 1.9e-05 23.6 4.1 0.00076 18.3 0.1 3.4 3 1 1 4 4 4 2 HI0933-like protein GMC_oxred_N PF00732.19 EMR62322.1 - 0.00022 20.7 0.0 0.045 13.1 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase GIDA PF01134.22 EMR62322.1 - 0.00052 19.2 4.5 0.0027 16.8 0.3 2.9 3 1 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EMR62322.1 - 0.00079 18.7 2.5 0.08 12.2 0.2 2.9 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR62322.1 - 0.037 13.3 0.0 0.52 9.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR62322.1 - 0.09 12.0 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain LCM PF04072.14 EMR62324.1 - 3.6e-20 72.7 0.0 5.6e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase HET PF06985.11 EMR62325.1 - 0.002 18.5 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lactamase_B_2 PF12706.7 EMR62326.1 - 9.8e-08 31.7 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMR62326.1 - 0.029 14.4 0.0 0.071 13.1 0.0 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Methyltransf_2 PF00891.18 EMR62327.1 - 8.5e-21 74.2 0.0 1.2e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PI-PLC-X PF00388.19 EMR62328.1 - 7e-64 213.8 0.0 1e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EMR62328.1 - 2.3e-42 144.0 0.0 4.2e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EMR62328.1 - 2.4e-06 27.8 0.0 1.2e-05 25.5 0.0 2.2 2 1 0 2 2 2 1 C2 domain EF-hand_like PF09279.11 EMR62328.1 - 0.042 14.3 0.3 0.71 10.4 0.3 2.4 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like YL1 PF05764.13 EMR62328.1 - 0.15 12.1 5.1 0.17 12.0 1.7 2.1 2 0 0 2 2 2 0 YL1 nuclear protein CCSAP PF15748.5 EMR62328.1 - 4.2 7.5 8.0 2 8.5 2.2 2.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated eIF3_subunit PF08597.10 EMR62328.1 - 4.2 7.2 10.5 1.4 8.7 1.8 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Amidohydro_1 PF01979.20 EMR62329.1 - 1.6e-23 83.6 0.1 1.5e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EMR62329.1 - 1.6e-14 54.3 0.2 1.2e-06 28.3 0.2 2.2 2 0 0 2 2 2 2 Amidohydrolase family Rad21_Rec8_N PF04825.13 EMR62330.1 - 4e-31 107.4 0.0 6.8e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EMR62330.1 - 2.9e-05 23.3 0.0 7.1e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein RNase_PH PF01138.21 EMR62331.1 - 4e-18 66.2 0.0 1.4e-17 64.4 0.0 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Flavin_Reduct PF01613.18 EMR62331.1 - 6.9 6.7 7.9 16 5.5 7.6 1.7 1 1 1 2 2 2 0 Flavin reductase like domain DUF2937 PF11157.8 EMR62333.1 - 0.071 12.8 0.6 0.15 11.8 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) RecG_N PF17190.4 EMR62333.1 - 0.075 13.8 1.3 1.2 9.9 0.2 2.8 3 1 0 3 3 3 0 RecG N-terminal helical domain DUF2524 PF10732.9 EMR62333.1 - 0.94 9.8 6.6 0.25 11.7 2.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) Tyrosinase PF00264.20 EMR62334.1 - 4.4e-31 108.9 2.7 4.4e-31 108.9 2.7 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase PAP1 PF08601.10 EMR62334.1 - 0.78 9.4 16.5 1.2 8.8 16.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SOG2 PF10428.9 EMR62334.1 - 1.7 7.8 15.1 2.2 7.4 15.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ferric_reduct PF01794.19 EMR62335.1 - 2.7e-19 69.5 3.3 2.7e-19 69.5 3.3 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMR62335.1 - 1.4e-12 47.6 0.2 6.2e-12 45.6 0.0 2.2 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 EMR62335.1 - 4e-09 36.8 0.0 5.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EMR62335.1 - 0.14 12.8 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain NAD_binding_8 PF13450.6 EMR62336.1 - 1.1e-09 38.4 0.3 3.1e-09 36.9 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMR62336.1 - 9.5e-09 35.0 0.0 3.5e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EMR62336.1 - 3.7e-06 26.6 0.2 5.9e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR62336.1 - 7.4e-05 22.0 0.6 0.0001 21.5 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMR62336.1 - 0.00012 20.9 0.2 0.00017 20.4 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EMR62336.1 - 0.00018 20.8 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR62336.1 - 0.00021 21.0 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR62336.1 - 0.0021 18.6 0.2 0.014 16.0 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 EMR62336.1 - 0.0063 16.1 0.1 0.0093 15.6 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_3 PF01494.19 EMR62336.1 - 0.024 13.9 0.2 0.033 13.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EMR62336.1 - 0.047 12.9 0.3 0.072 12.3 0.3 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 EMR62336.1 - 0.059 13.8 0.2 0.26 11.8 0.2 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EMR62336.1 - 0.1 12.2 0.4 0.2 11.3 0.2 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EMR62336.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 EMR62336.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EMR62337.1 - 3.5e-20 72.0 0.0 3.2e-18 65.5 0.0 2.1 1 1 0 1 1 1 1 GDP dissociation inhibitor AIM5 PF17050.5 EMR62338.1 - 7.7e-21 74.7 5.3 1.6e-20 73.6 5.3 1.6 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 TPR_10 PF13374.6 EMR62338.1 - 0.4 10.6 4.3 1.4 8.9 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MitMem_reg PF13012.6 EMR62339.1 - 4.3e-18 65.8 0.1 9e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EMR62339.1 - 1.8e-13 50.5 0.0 3.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3446 PF11928.8 EMR62339.1 - 0.03 14.6 1.7 0.069 13.5 1.7 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain GRP PF07172.11 EMR62339.1 - 0.11 13.2 14.0 0.2 12.3 14.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_L17 PF01196.19 EMR62340.1 - 3.5e-32 111.2 0.4 1.6e-31 109.1 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 TFB6 PF17110.5 EMR62342.1 - 0.0011 18.8 0.9 0.0025 17.6 0.9 1.6 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH DUF2870 PF11069.8 EMR62342.1 - 1.1 9.7 6.2 19 5.7 1.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) UTP25 PF06862.12 EMR62343.1 - 4.2e-176 586.4 0.0 5.2e-176 586.1 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EMR62343.1 - 0.014 15.1 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase cwf18 PF08315.12 EMR62344.1 - 5.4e-44 150.1 3.8 5.4e-44 150.1 3.8 1.9 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Pam16 PF03656.13 EMR62344.1 - 0.015 15.3 0.7 0.015 15.3 0.7 1.9 2 0 0 2 2 2 0 Pam16 Myc_N PF01056.18 EMR62344.1 - 0.27 11.1 4.0 1.8 8.4 0.3 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Sde2_N_Ubi PF13019.6 EMR62346.1 - 1 9.2 2.4 0.74 9.6 0.1 1.9 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Cofilin_ADF PF00241.20 EMR62347.1 - 4.3e-24 84.6 0.0 4.8e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ivy PF08816.11 EMR62347.1 - 0.043 14.0 0.0 2.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) PD40 PF07676.12 EMR62348.1 - 5.3e-53 176.0 15.5 9.7e-08 31.8 0.1 10.0 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EMR62348.1 - 1.9e-11 43.4 7.9 0.024 13.4 0.2 7.4 4 2 1 6 6 6 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 EMR62348.1 - 2.9e-08 33.3 0.0 0.0029 16.9 0.0 4.1 4 1 0 4 4 4 2 Domain of unknown function (DUF5050) DUF3748 PF12566.8 EMR62348.1 - 0.00024 21.0 1.0 7 6.6 0.1 5.2 5 1 0 5 5 5 1 Protein of unknown function (DUF3748) Gmad1 PF10647.9 EMR62348.1 - 0.00061 19.6 0.5 0.026 14.3 0.2 3.5 3 2 2 5 5 5 1 Lipoprotein LpqB beta-propeller domain WD40 PF00400.32 EMR62348.1 - 0.059 14.3 9.9 45 5.1 0.6 6.8 7 1 0 7 7 7 0 WD domain, G-beta repeat DUF1513 PF07433.11 EMR62348.1 - 0.079 12.0 0.0 18 4.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) TruB_C PF09142.11 EMR62348.1 - 0.094 12.5 0.0 77 3.2 0.0 4.3 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal GspH PF12019.8 EMR62348.1 - 0.26 11.7 10.4 0.37 11.2 0.1 3.8 2 2 2 4 4 4 0 Type II transport protein GspH Proteasome_A_N PF10584.9 EMR62348.1 - 1.5 8.5 11.4 61 3.4 0.0 6.8 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature F-box-like PF12937.7 EMR62349.1 - 0.026 14.4 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like IKI3 PF04762.12 EMR62350.1 - 1.8e-90 304.3 0.4 2e-81 274.4 0.7 2.1 1 1 1 2 2 2 2 IKI3 family RabGAP-TBC PF00566.18 EMR62353.1 - 2.8e-15 56.5 0.2 5e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EMR62353.1 - 7.7e-06 25.4 0.4 0.0084 16.0 0.3 3.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EMR62353.1 - 5.7e-05 22.4 4.8 0.045 13.3 0.6 4.2 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 EMR62353.1 - 0.0056 16.1 0.5 0.088 12.3 0.2 3.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EMR62353.1 - 0.03 14.8 5.6 0.043 14.3 0.5 3.5 3 1 2 5 5 5 0 EF-hand domain pair DUF4611 PF15387.6 EMR62353.1 - 5.8 7.2 9.2 13 6.0 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) WSC PF01822.19 EMR62354.1 - 5.1e-24 84.3 30.0 6e-10 39.2 2.6 3.7 3 0 0 3 3 3 3 WSC domain PIF2 PF04631.12 EMR62354.1 - 0.056 12.3 0.4 0.1 11.4 0.1 1.6 2 0 0 2 2 2 0 Per os infectivity factor 2 zf-RING_UBOX PF13445.6 EMR62355.1 - 0.059 13.4 4.5 0.14 12.2 4.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger TFIIA PF03153.13 EMR62355.1 - 0.27 11.2 20.9 0.34 10.9 20.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLP1_P PF16575.5 EMR62355.1 - 0.29 10.9 3.6 0.45 10.3 3.6 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VIR_N PF15912.5 EMR62355.1 - 0.38 10.3 8.5 0.5 9.9 8.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal EIIBC-GUT_N PF03612.14 EMR62355.1 - 1.2 8.9 6.6 1.7 8.3 6.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus zf-C3HC4_3 PF13920.6 EMR62355.1 - 7.1 6.6 9.3 1.5 8.8 3.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMR62355.1 - 9.4 6.3 11.3 0.091 12.7 2.8 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Presenilin PF01080.17 EMR62355.1 - 9.6 4.8 10.3 12 4.6 10.3 1.1 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 EMR62356.1 - 3.3e-22 78.9 35.6 3.3e-22 78.9 35.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ALO PF04030.14 EMR62357.1 - 7e-93 311.2 2.5 1e-92 310.7 2.5 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EMR62357.1 - 1.5e-27 96.0 0.0 2.3e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BTB PF00651.31 EMR62358.1 - 2.9e-21 75.8 0.5 2.7e-11 43.7 0.3 3.0 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 EMR62358.1 - 1e-07 32.3 0.0 3.6e-07 30.6 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR62358.1 - 1.4e-07 32.0 0.0 3.9e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR62358.1 - 3.5e-06 27.2 0.0 1.2e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR62358.1 - 2.6e-05 24.3 0.2 0.18 12.4 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EMR62358.1 - 2.8e-05 24.4 0.1 0.021 15.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Pkinase PF00069.25 EMR62359.1 - 9.9e-66 221.8 0.0 1.2e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR62359.1 - 8e-33 113.8 0.0 1e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR62359.1 - 1.6e-05 24.4 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMR62359.1 - 0.0043 17.0 0.1 0.021 14.8 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMR62359.1 - 0.028 13.2 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EMR62359.1 - 0.038 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EMR62359.1 - 0.092 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 EMR62360.1 - 3.7e-46 157.6 0.0 7.6e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR62360.1 - 1.8e-31 109.3 0.1 1.2e-30 106.7 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3770 PF12603.8 EMR62360.1 - 0.011 15.2 1.2 0.011 15.2 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3770) DUF99 PF01949.16 EMR62360.1 - 0.041 13.3 0.6 0.13 11.7 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF99 HAGH_C PF16123.5 EMR62360.1 - 0.12 12.8 2.0 0.33 11.5 2.0 1.7 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus HI0933_like PF03486.14 EMR62360.1 - 1 8.0 2.7 1.7 7.3 2.7 1.2 1 0 0 1 1 1 0 HI0933-like protein OmpH PF03938.14 EMR62360.1 - 1.4 9.2 9.9 3.4 8.0 9.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3896 PF13035.6 EMR62360.1 - 2.5 8.3 6.4 0.28 11.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) PAXX PF15384.6 EMR62361.1 - 0.038 13.7 0.4 12 5.5 0.1 2.8 1 1 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Glyco_hydro_65C PF03633.15 EMR62361.1 - 0.17 11.8 8.2 7.2 6.6 0.2 4.1 3 1 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain FAM184 PF15665.5 EMR62363.1 - 0.15 11.9 7.5 0.24 11.2 7.5 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF2205 PF10224.9 EMR62363.1 - 0.16 12.0 5.6 0.058 13.4 2.2 2.0 2 0 0 2 2 2 0 Short coiled-coil protein zf-C4H2 PF10146.9 EMR62363.1 - 0.48 10.7 4.0 0.53 10.6 4.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein APG6_N PF17675.1 EMR62363.1 - 4 8.0 12.1 0.14 12.7 5.9 1.8 3 0 0 3 3 3 0 Apg6 coiled-coil region Choline_kinase PF01633.20 EMR62364.1 - 0.037 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EMR62364.1 - 0.18 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase SHR3_chaperone PF08229.11 EMR62365.1 - 0.15 11.0 4.4 0.24 10.3 4.4 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 DUF5453 PF17534.2 EMR62365.1 - 0.28 11.1 5.3 0.093 12.7 2.7 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5453) DUF2070 PF09843.9 EMR62365.1 - 5.9 5.0 8.0 7.6 4.7 8.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) COX7C PF02935.16 EMR62366.1 - 8.8e-23 80.3 3.2 1.3e-22 79.8 3.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DUF4019 PF13211.6 EMR62366.1 - 0.12 12.8 0.1 0.15 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) CPSF73-100_C PF11718.8 EMR62367.1 - 3.9e-86 288.1 0.1 6e-86 287.5 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EMR62367.1 - 1.2e-30 106.1 0.0 2.2e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EMR62367.1 - 2.5e-18 66.2 0.1 4.2e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EMR62367.1 - 5.6e-18 65.6 1.3 5.6e-18 65.6 1.3 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EMR62367.1 - 8.8e-13 48.0 0.0 1.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EMR62367.1 - 1.4e-05 24.7 0.7 3.7e-05 23.3 0.7 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMR62367.1 - 2.7e-05 24.1 0.1 2.7e-05 24.1 0.1 1.9 2 0 0 2 2 1 1 Beta-lactamase superfamily domain Myc_N PF01056.18 EMR62367.1 - 0.016 15.2 5.2 0.03 14.2 5.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region SAPS PF04499.15 EMR62367.1 - 0.035 12.9 2.3 0.046 12.5 2.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Beta_lactamase3 PF17030.5 EMR62367.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family CCDC53 PF10152.9 EMR62367.1 - 0.42 11.0 7.4 0.55 10.6 6.2 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4746 PF15928.5 EMR62367.1 - 2.1 7.7 8.9 4.7 6.5 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 EMR62367.1 - 4.9 7.6 6.2 12 6.3 3.9 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 CN_hydrolase PF00795.22 EMR62368.1 - 3.2e-39 134.9 0.3 1.5e-37 129.4 0.3 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Mucin PF01456.17 EMR62368.1 - 0.096 12.7 15.8 0.15 12.0 15.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2586 PF10758.9 EMR62368.1 - 0.11 11.6 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) DUF2407_C PF13373.6 EMR62369.1 - 5.7e-34 117.3 0.0 8.2e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EMR62369.1 - 6.6e-28 97.3 0.0 1.3e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EMR62369.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 2 0 0 2 2 2 0 Ubiquitin family Ala_racemase_N PF01168.20 EMR62370.1 - 4.4e-19 69.0 0.3 3.6e-18 66.0 0.3 1.9 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain LSM14 PF12701.7 EMR62371.1 - 9.4e-31 105.8 0.0 1.6e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EMR62371.1 - 1.9e-22 80.1 0.5 4e-22 79.1 0.5 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 EMR62371.1 - 3e-07 30.5 0.0 5.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain NAD_binding_4 PF07993.12 EMR62372.1 - 2.3e-06 27.0 0.0 3.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein rRNA_proc-arch PF13234.6 EMR62373.1 - 3e-82 276.6 0.0 7.2e-82 275.3 0.0 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EMR62373.1 - 1.4e-48 164.6 2.3 1.9e-48 164.2 0.7 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 EMR62373.1 - 1.7e-19 70.3 0.0 8.1e-19 68.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR62373.1 - 7.7e-08 32.7 0.0 4.3e-07 30.3 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR62373.1 - 1.4e-05 25.2 0.0 5.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EMR62373.1 - 0.036 13.1 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EMR62373.1 - 0.041 14.1 0.0 0.53 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EMR62373.1 - 0.14 12.0 1.3 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TGF_beta_GS PF08515.12 EMR62374.1 - 0.51 9.9 3.3 1 8.9 3.3 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif TAF4 PF05236.14 EMR62376.1 - 3.5e-27 95.9 0.1 6.5e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family DUF202 PF02656.15 EMR62377.1 - 3.2e-16 59.5 3.5 3.2e-16 59.5 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4231 PF14015.6 EMR62377.1 - 1.3 9.5 4.9 0.4 11.2 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Ferric_reduct PF01794.19 EMR62378.1 - 8.2e-15 55.0 12.9 2.1e-14 53.7 12.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMR62378.1 - 1.5e-14 54.4 0.0 1.8e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR62378.1 - 4.6e-12 46.0 0.0 1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EMR62378.1 - 0.067 13.8 0.0 8.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Sigma_M_inh PF17453.2 EMR62378.1 - 10 6.7 8.7 10 6.6 0.2 3.0 1 1 1 3 3 3 0 Sigma-M inhibitor RTA1 PF04479.13 EMR62379.1 - 1.3e-39 135.9 15.9 1.7e-39 135.5 15.9 1.1 1 0 0 1 1 1 1 RTA1 like protein TMEM125 PF15109.6 EMR62379.1 - 0.083 13.2 2.4 0.15 12.4 0.2 2.4 1 1 2 3 3 3 0 TMEM125 protein family Alba PF01918.21 EMR62381.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.7 1 1 0 1 1 1 0 Alba WRNPLPNID PF15017.6 EMR62381.1 - 0.15 12.9 2.6 0.18 12.7 1.2 1.9 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RNA_pol_3_Rpc31 PF11705.8 EMR62381.1 - 0.69 10.1 13.7 1.3 9.2 13.7 1.7 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRM_1 PF00076.22 EMR62382.1 - 4.5e-16 58.4 0.0 6.6e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMR62382.1 - 0.03 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nucleo_P87 PF07267.11 EMR62383.1 - 0.068 12.0 1.7 0.097 11.5 1.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Fez1 PF06818.15 EMR62384.1 - 3.2e-06 27.7 30.6 0.0015 19.1 0.0 4.3 3 1 2 5 5 4 2 Fez1 ATG16 PF08614.11 EMR62384.1 - 1.9e-05 25.0 46.9 0.0013 19.0 13.4 4.9 2 1 2 4 4 4 2 Autophagy protein 16 (ATG16) DHR10 PF18595.1 EMR62384.1 - 0.00015 21.8 13.6 0.00015 21.8 13.6 6.4 4 2 3 7 7 6 1 Designed helical repeat protein 10 domain BORCS7 PF16088.5 EMR62384.1 - 0.066 13.5 7.5 0.11 12.8 2.2 3.4 2 1 0 3 3 3 0 BLOC-1-related complex sub-unit 7 PRKG1_interact PF15898.5 EMR62384.1 - 0.14 13.0 0.2 0.14 13.0 0.2 6.5 3 1 4 7 7 7 0 cGMP-dependent protein kinase interacting domain MLTR_LBD PF17765.1 EMR62384.1 - 0.22 11.6 2.6 0.28 11.3 0.7 2.2 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain FlaC_arch PF05377.11 EMR62384.1 - 0.3 11.5 25.5 3.4 8.1 1.2 7.2 4 2 4 8 8 8 0 Flagella accessory protein C (FlaC) MbeD_MobD PF04899.12 EMR62384.1 - 0.61 10.3 13.5 0.072 13.2 1.5 4.6 5 0 0 5 5 5 0 MbeD/MobD like MAD PF05557.13 EMR62384.1 - 0.71 8.2 52.8 0.11 10.9 14.4 4.6 3 1 2 5 5 5 0 Mitotic checkpoint protein Endotoxin_N PF03945.14 EMR62384.1 - 1.2 8.8 3.5 1.2 8.7 0.0 2.7 2 1 1 3 3 3 0 delta endotoxin, N-terminal domain BST2 PF16716.5 EMR62384.1 - 1.3 9.6 47.3 5 7.8 0.5 8.6 3 1 4 8 8 8 0 Bone marrow stromal antigen 2 TBPIP_N PF15517.6 EMR62384.1 - 4 7.5 9.5 6.5 6.9 1.5 3.1 1 1 3 4 4 4 0 TBP-interacting protein N-terminus ABC_tran_CTD PF16326.5 EMR62384.1 - 4.2 7.7 49.9 0.49 10.7 2.3 8.1 4 3 3 7 7 7 0 ABC transporter C-terminal domain adh_short PF00106.25 EMR62384.1 - 4.7 6.6 9.1 1.4 8.3 0.0 3.4 3 1 1 4 4 4 0 short chain dehydrogenase DUF3573 PF12097.8 EMR62384.1 - 8.6 5.1 8.0 1.6 7.5 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3573) Bcr-Abl_Oligo PF09036.10 EMR62384.1 - 9.9 6.2 22.8 14 5.7 0.6 6.7 3 1 3 6 6 6 0 Bcr-Abl oncoprotein oligomerisation domain Ion_trans PF00520.31 EMR62385.1 - 3.9e-06 26.3 1.9 5.2e-06 25.9 1.9 1.2 1 0 0 1 1 1 1 Ion transport protein Mto2_bdg PF12808.7 EMR62385.1 - 0.0066 16.7 0.7 0.013 15.8 0.7 1.4 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Srg PF02118.21 EMR62385.1 - 0.012 15.3 0.2 0.015 14.9 0.2 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor HalX PF08663.10 EMR62385.1 - 0.017 15.4 1.9 0.027 14.8 1.9 1.3 1 0 0 1 1 1 0 HalX domain ABC2_membrane PF01061.24 EMR62385.1 - 0.03 13.7 0.2 0.035 13.5 0.2 1.1 1 0 0 1 1 1 0 ABC-2 type transporter TPR_MLP1_2 PF07926.12 EMR62385.1 - 0.033 14.3 0.5 0.054 13.6 0.5 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Frigida PF07899.11 EMR62385.1 - 0.082 12.2 0.7 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Frigida-like protein CTP_transf_like PF01467.26 EMR62386.1 - 4e-31 108.1 0.0 6.1e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Fungal_trans PF04082.18 EMR62387.1 - 2.2e-12 46.6 0.2 3.6e-12 45.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FSA_C PF10479.9 EMR62387.1 - 0.25 9.5 2.5 0.38 8.8 2.5 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Glyco_hydro_88 PF07470.13 EMR62388.1 - 7.1e-59 199.6 3.2 8.5e-59 199.3 3.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EMR62388.1 - 0.041 12.4 0.3 0.062 11.8 0.3 1.2 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 F-box-like PF12937.7 EMR62389.1 - 0.0036 17.2 0.1 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 F-box-like Methyltransf_23 PF13489.6 EMR62390.1 - 7.9e-21 74.6 0.0 1.4e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR62390.1 - 1.8e-12 47.8 0.0 6.5e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR62390.1 - 1.2e-10 41.9 0.0 3.9e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR62390.1 - 3.2e-09 37.4 0.0 3.2e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR62390.1 - 3.2e-08 33.5 0.0 0.00076 19.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EMR62390.1 - 6.7e-06 25.6 0.1 0.00013 21.4 0.1 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EMR62390.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EMR62390.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EMR62390.1 - 0.002 17.7 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EMR62390.1 - 0.0064 16.0 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 EMR62390.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 EMR62390.1 - 0.15 11.3 0.0 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain HECT PF00632.25 EMR62391.1 - 1.6e-95 320.2 0.0 2.1e-95 319.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EMR62391.1 - 6.3e-33 112.6 24.7 2.8e-11 43.3 6.3 3.9 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EMR62391.1 - 2.5e-17 63.1 0.0 7.7e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 C2 domain Tctex-1 PF03645.13 EMR62393.1 - 2.2e-36 124.2 0.0 2.5e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family AMPK1_CBM PF16561.5 EMR62394.1 - 6.9e-22 77.5 0.1 1.3e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EMR62394.1 - 0.016 15.6 0.1 0.034 14.5 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 EMR62394.1 - 0.057 14.0 0.2 0.15 12.6 0.2 1.7 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) DHO_dh PF01180.21 EMR62395.1 - 2.5e-11 43.4 0.3 3.4e-08 33.0 0.2 2.7 2 1 0 2 2 2 2 Dihydroorotate dehydrogenase GGDEF_2 PF17853.1 EMR62395.1 - 0.093 13.0 0.1 0.86 9.9 0.0 2.4 3 0 0 3 3 3 0 GGDEF-like domain FANCD2OS PF15124.6 EMR62395.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 FANCD2 opposite strand protein Oxidored_q6 PF01058.22 EMR62396.1 - 2.7e-22 79.0 0.0 4e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit F_actin_cap_B PF01115.17 EMR62397.1 - 0.035 13.8 0.8 0.037 13.7 0.8 1.0 1 0 0 1 1 1 0 F-actin capping protein, beta subunit Tmemb_cc2 PF10267.9 EMR62397.1 - 0.41 9.7 3.9 0.46 9.6 3.9 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein NAD_binding_8 PF13450.6 EMR62399.1 - 8.9e-06 25.9 1.3 2.2e-05 24.6 0.6 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR62399.1 - 1.4e-05 24.4 1.3 2.7e-05 23.4 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EMR62399.1 - 7.1e-05 22.2 3.8 0.035 13.4 0.7 2.6 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EMR62399.1 - 0.0012 18.1 0.6 0.0012 18.1 0.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR62399.1 - 0.0013 18.4 4.8 0.002 17.8 4.8 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR62399.1 - 0.0028 16.6 0.2 1.3 7.8 0.2 2.3 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 EMR62399.1 - 0.0029 16.8 1.2 0.0041 16.2 0.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EMR62399.1 - 0.0093 14.7 0.5 0.016 13.9 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EMR62399.1 - 0.059 12.6 0.3 0.11 11.7 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR62399.1 - 0.082 12.2 1.3 0.21 10.9 1.3 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMR62399.1 - 0.089 12.1 2.7 0.09 12.1 0.5 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EMR62399.1 - 0.097 13.2 0.6 0.26 11.9 0.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lumazine_bd_2 PF12893.7 EMR62400.1 - 0.027 15.2 0.3 0.061 14.0 0.1 1.7 2 0 0 2 2 2 0 Putative lumazine-binding DUF1992 PF09350.10 EMR62401.1 - 7.4e-21 74.1 1.3 1.6e-20 73.0 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) PEP_mutase PF13714.6 EMR62402.1 - 3.2e-47 161.0 2.3 3.7e-47 160.8 2.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EMR62402.1 - 5e-20 71.5 1.2 8.2e-20 70.8 1.2 1.4 1 0 0 1 1 1 1 Isocitrate lyase family MR_MLE_C PF13378.6 EMR62402.1 - 0.061 12.9 0.4 0.12 12.0 0.1 1.6 2 0 0 2 2 2 0 Enolase C-terminal domain-like DUF3433 PF11915.8 EMR62404.1 - 1.4e-26 92.7 14.0 1.3e-16 60.8 2.7 3.9 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Glyco_transf_22 PF03901.17 EMR62404.1 - 0.78 8.9 11.2 0.025 13.8 1.8 2.5 3 0 0 3 3 3 0 Alg9-like mannosyltransferase family MFS_1 PF07690.16 EMR62405.1 - 3.7e-25 88.6 49.2 2.3e-23 82.7 47.7 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR62405.1 - 1.1e-21 77.0 19.9 1.4e-21 76.5 19.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2964 PF11177.8 EMR62405.1 - 1.9 8.7 7.4 2.4 8.4 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) AcetylCoA_hydro PF02550.15 EMR62406.1 - 8.1e-50 169.5 0.0 1.6e-49 168.6 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EMR62406.1 - 2.5e-39 134.7 0.0 3.7e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain 7TM_GPCR_Srd PF10317.9 EMR62407.1 - 0.027 13.6 3.3 0.045 13.0 3.3 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Bromodomain PF00439.25 EMR62408.1 - 2.6e-17 62.6 0.0 6.2e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 EMR62408.1 - 4.7e-09 36.4 0.0 3.3e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BUD22 PF09073.10 EMR62409.1 - 2.1 7.6 36.4 3.2 7.0 36.4 1.3 1 0 0 1 1 1 0 BUD22 SAP30_Sin3_bdg PF13867.6 EMR62411.1 - 7.2e-09 35.8 0.7 1.3e-07 31.9 0.1 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Mit_KHE1 PF10173.9 EMR62412.1 - 2.3e-59 200.7 0.1 2.3e-59 200.7 0.1 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related DUF588 PF04535.12 EMR62413.1 - 0.002 17.9 0.4 0.0029 17.4 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) MgtE PF01769.16 EMR62413.1 - 0.1 13.0 5.3 1.1 9.6 0.3 2.5 1 1 2 3 3 3 0 Divalent cation transporter BRO1 PF03097.18 EMR62414.1 - 1.2e-132 442.4 2.3 1.2e-132 442.4 2.3 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EMR62414.1 - 1.2e-79 267.7 16.6 2.7e-79 266.5 16.6 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV COG2 PF06148.11 EMR62414.1 - 0.17 12.0 4.5 0.58 10.2 1.5 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Avl9 PF09794.9 EMR62415.1 - 4.1e-62 210.1 0.2 2.9e-36 125.0 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 EMR62415.1 - 0.043 13.4 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) IHABP4_N PF16174.5 EMR62415.1 - 0.13 12.8 12.9 0.48 11.0 0.6 2.6 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Plasmodium_Vir PF05795.11 EMR62415.1 - 5.6 6.3 5.5 10 5.4 5.5 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAS PF00989.25 EMR62416.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 PAS fold DnaJ_C PF01556.18 EMR62417.1 - 1.5e-38 132.2 0.0 2.1e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMR62417.1 - 5.4e-23 80.9 2.4 1e-22 80.0 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMR62417.1 - 3.6e-09 36.9 22.2 6.6e-09 36.0 22.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EMR62417.1 - 0.0056 16.6 2.3 0.0056 16.6 2.3 2.6 2 0 0 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein FYVE PF01363.21 EMR62417.1 - 0.99 9.6 4.9 2.8 8.1 0.3 2.3 2 0 0 2 2 2 0 FYVE zinc finger Cullin PF00888.22 EMR62418.1 - 1.9e-193 644.5 12.3 2.4e-193 644.2 12.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EMR62418.1 - 8.2e-26 89.8 2.7 8.2e-26 89.8 2.7 2.4 4 0 0 4 4 4 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 EMR62418.1 - 0.0021 18.6 1.2 0.012 16.1 0.3 2.7 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal AnfG_VnfG PF03139.15 EMR62418.1 - 0.0079 16.3 2.1 0.14 12.2 0.8 2.8 2 0 0 2 2 2 1 Vanadium/alternative nitrogenase delta subunit FAM194 PF14977.6 EMR62418.1 - 0.08 12.3 1.6 0.91 8.8 0.4 2.6 2 0 0 2 2 2 0 FAM194 protein Glyco_hydro_67M PF07488.12 EMR62419.1 - 9.4e-145 481.7 0.3 1.3e-144 481.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 EMR62419.1 - 4.7e-89 297.7 1.2 7.3e-89 297.1 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 EMR62419.1 - 4.5e-28 98.0 0.0 8.1e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 EMR62419.1 - 0.015 16.1 0.1 0.056 14.2 0.1 2.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 BetaGal_dom4_5 PF13364.6 EMR62419.1 - 0.039 14.5 0.0 0.098 13.2 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain DUF4859 PF16151.5 EMR62419.1 - 0.11 12.3 5.7 8.7 6.2 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4859) TssC PF17541.2 EMR62420.1 - 0.11 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB ANAPC15 PF15243.6 EMR62420.1 - 0.64 10.5 9.4 1.5 9.3 9.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 NOA36 PF06524.12 EMR62420.1 - 8.9 5.5 15.4 13 5.0 15.4 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_88 PF07470.13 EMR62421.1 - 1.5e-40 139.4 1.6 1.9e-40 139.0 1.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CLP1_P PF16575.5 EMR62422.1 - 1.1e-32 113.4 0.0 1.7e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Iso_dh PF00180.20 EMR62424.1 - 2.3e-80 270.3 0.0 2.7e-80 270.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CMD PF02627.20 EMR62425.1 - 0.0045 17.0 0.3 0.053 13.6 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family MyTH4 PF00784.17 EMR62425.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 MyTH4 domain TPR_20 PF14561.6 EMR62425.1 - 0.13 12.6 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3176 PF11374.8 EMR62426.1 - 6.4e-22 77.8 0.3 1.3e-21 76.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF5589 PF17672.1 EMR62426.1 - 0.033 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5589) Pkinase PF00069.25 EMR62427.1 - 1.9e-67 227.4 0.0 3.2e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR62427.1 - 6.5e-51 173.1 0.0 1.3e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR62427.1 - 0.00043 19.2 0.6 0.0012 17.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 EMR62427.1 - 0.031 14.4 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Kinase-like PF14531.6 EMR62427.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 Kinase-like NTP_transf_6 PF06042.11 EMR62428.1 - 2.4e-39 134.8 0.2 2.3e-38 131.6 0.2 1.9 1 1 0 1 1 1 1 Nucleotidyltransferase Glyco_hydro_16 PF00722.21 EMR62429.1 - 3.3e-35 121.1 3.2 4.7e-35 120.7 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 EMR62430.1 - 1.5e-15 57.0 62.7 2.4e-15 56.3 57.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Ferlin_C PF16165.5 EMR62431.1 - 0.097 12.6 1.6 0.2 11.6 1.6 1.5 1 0 0 1 1 1 0 Ferlin C-terminus TrkH PF02386.16 EMR62432.1 - 3.8e-89 299.4 0.0 1.2e-83 281.3 0.0 2.6 2 1 0 2 2 2 2 Cation transport protein RPS31 PF17067.5 EMR62432.1 - 0.11 12.6 0.2 31 4.8 0.0 2.8 1 1 1 2 2 2 0 Ribosomal protein S31e DUF5313 PF17240.2 EMR62433.1 - 0.08 13.4 1.3 0.15 12.5 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5313) DUF805 PF05656.14 EMR62433.1 - 0.11 12.9 11.6 0.084 13.3 7.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF2721 PF11026.8 EMR62433.1 - 3.4 7.6 8.1 2.3 8.1 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) DNA_methylase PF00145.17 EMR62434.1 - 1.9e-56 191.8 0.0 1.8e-44 152.4 0.0 2.0 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Met_10 PF02475.16 EMR62434.1 - 0.0042 16.8 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_2 PF00891.18 EMR62435.1 - 8.9e-20 70.9 0.0 1.2e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain p450 PF00067.22 EMR62436.1 - 6.2e-21 74.7 0.0 9.8e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 EMR62437.1 - 4.8e-06 26.3 0.7 8.4e-06 25.5 0.0 1.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FleQ PF06490.11 EMR62437.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ AA_permease_2 PF13520.6 EMR62438.1 - 1.8e-40 139.1 51.5 2.3e-40 138.7 51.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR62438.1 - 1.2e-16 60.4 50.3 2.1e-16 59.6 50.3 1.3 1 1 0 1 1 1 1 Amino acid permease NAD_binding_10 PF13460.6 EMR62440.1 - 3.7e-16 59.5 0.0 7.3e-16 58.6 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMR62440.1 - 6.1e-11 42.3 0.0 1.2e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family GST_N_2 PF13409.6 EMR62442.1 - 2e-16 60.0 0.0 4.4e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR62442.1 - 6e-08 32.6 0.0 2.5e-07 30.6 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain CBM_5_12_2 PF14600.6 EMR62442.1 - 0.083 12.8 0.5 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Cellulose-binding domain GST_C_3 PF14497.6 EMR62442.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR62442.1 - 0.13 12.7 0.0 19 5.7 0.0 2.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Citrate_bind PF16114.5 EMR62444.1 - 3e-85 284.2 0.0 4.1e-85 283.7 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EMR62444.1 - 1.5e-06 28.0 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain MFS_1 PF07690.16 EMR62445.1 - 7.1e-11 41.6 20.5 7.1e-11 41.6 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR62445.1 - 0.045 12.6 0.0 0.045 12.6 0.0 2.5 2 1 0 2 2 2 0 Sugar (and other) transporter Flt3_lig PF02947.14 EMR62445.1 - 0.14 12.4 0.0 0.96 9.6 0.0 2.0 2 0 0 2 2 2 0 flt3 ligand Citrate_synt PF00285.21 EMR62446.1 - 2.1e-20 73.1 0.0 1.6e-17 63.6 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EMR62446.1 - 1.2e-18 67.5 0.0 3.8e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 EMR62446.1 - 5.7e-14 52.2 0.3 1.1e-13 51.3 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EMR62446.1 - 2.8e-05 23.9 0.2 0.00091 19.0 0.0 2.6 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CDH PF02611.15 EMR62447.1 - 0.051 13.2 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Zn_clus PF00172.18 EMR62448.1 - 0.0002 21.4 6.5 0.00049 20.1 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.8 EMR62448.1 - 0.11 12.5 4.1 0.17 11.8 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3446 PF11928.8 EMR62448.1 - 4.6 7.6 11.0 2.2 8.6 4.2 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Cu-oxidase_2 PF07731.14 EMR62450.1 - 4.7e-36 123.5 1.1 2.3e-35 121.3 0.1 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EMR62450.1 - 5.3e-29 101.4 0.0 1.5e-28 99.9 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMR62450.1 - 3.8e-25 88.2 0.5 5.3e-23 81.3 0.3 2.7 2 0 0 2 2 2 2 Multicopper oxidase Hexapep PF00132.24 EMR62451.1 - 1.1e-06 28.1 0.6 0.0034 17.0 0.1 3.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EMR62451.1 - 0.00023 20.3 0.1 0.00026 20.1 0.1 1.1 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EMR62451.1 - 0.0005 18.3 0.3 0.0018 16.5 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) zf-C2H2 PF00096.26 EMR62452.1 - 8.6e-05 22.8 15.7 0.0028 18.0 2.0 3.4 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR62452.1 - 0.00026 21.6 17.6 0.0026 18.5 1.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMR62452.1 - 0.0022 18.3 13.7 0.0083 16.5 6.3 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMR62452.1 - 0.0039 17.4 2.7 0.032 14.5 0.4 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMR62452.1 - 0.025 15.0 1.1 0.063 13.7 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 EMR62452.1 - 0.054 13.4 3.9 0.12 12.3 3.9 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 EMR62452.1 - 0.27 11.6 7.2 0.83 10.0 7.3 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Meth_synt_2 PF01717.18 EMR62453.1 - 1.3e-150 501.2 0.0 3.8e-146 486.5 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EMR62453.1 - 1.5e-117 392.6 0.2 2.3e-110 369.0 0.0 3.1 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EMR62453.1 - 0.0019 17.4 0.0 0.054 12.6 0.0 2.4 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) Tudor-knot PF11717.8 EMR62454.1 - 4.5e-09 36.1 0.0 7.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RAP1 PF07218.11 EMR62455.1 - 0.14 10.5 1.0 0.18 10.1 1.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UCR_TM PF02921.14 EMR62455.1 - 2.2 8.8 5.2 1.7 9.2 0.2 3.1 4 0 0 4 4 4 0 Ubiquinol cytochrome reductase transmembrane region Abhydrolase_2 PF02230.16 EMR62456.1 - 1.1e-21 77.6 0.0 6.1e-21 75.2 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EMR62456.1 - 0.00016 21.2 0.0 0.00034 20.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EMR62456.1 - 0.0018 18.0 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EMR62456.1 - 0.012 15.4 0.0 5.3 6.8 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold CENP-Q PF13094.6 EMR62457.1 - 9.7e-49 165.8 0.0 9.7e-49 165.8 0.0 3.0 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF1541 PF07563.11 EMR62457.1 - 0.14 12.0 0.3 0.28 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Cnl2_NKP2 PF09447.10 EMR62458.1 - 1.3e-26 92.5 1.6 2.4e-26 91.7 1.6 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein APG6_N PF17675.1 EMR62458.1 - 0.0032 18.0 7.4 0.023 15.2 0.2 2.1 2 0 0 2 2 2 2 Apg6 coiled-coil region XhlA PF10779.9 EMR62458.1 - 0.036 14.3 1.0 0.083 13.1 0.7 1.8 2 0 0 2 2 2 0 Haemolysin XhlA YabA PF06156.13 EMR62458.1 - 0.058 14.0 3.5 2.5 8.8 0.5 2.2 2 0 0 2 2 2 0 Initiation control protein YabA MIF4G_like_2 PF09090.11 EMR62458.1 - 0.061 12.8 1.7 0.084 12.3 1.7 1.2 1 0 0 1 1 1 0 MIF4G like Tektin PF03148.14 EMR62458.1 - 0.16 10.7 8.4 0.07 11.9 0.4 2.0 1 1 1 2 2 2 0 Tektin family DUF4407 PF14362.6 EMR62458.1 - 0.22 10.8 2.1 0.28 10.5 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 EMR62458.1 - 3.8 7.0 8.6 4.8 6.7 1.5 2.2 1 1 1 2 2 2 0 fzo-like conserved region Steroid_dh PF02544.16 EMR62459.1 - 2.2e-22 79.7 0.8 9.3e-22 77.6 0.8 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EMR62459.1 - 4.4e-07 29.7 0.3 8.5e-07 28.7 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) HET PF06985.11 EMR62460.1 - 9.6e-20 71.4 0.0 2.7e-19 70.0 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gly_transf_sug PF04488.15 EMR62461.1 - 9.2e-11 42.2 0.0 1.9e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EMR62461.1 - 8.8e-07 28.6 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EMR62461.1 - 0.089 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Spt20 PF12090.8 EMR62463.1 - 0.0039 16.8 0.1 0.0039 16.8 0.1 7.0 5 2 2 7 7 7 1 Spt20 family NmrA PF05368.13 EMR62464.1 - 5.2e-35 121.1 0.0 7.2e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR62464.1 - 8.1e-17 61.7 0.0 9.7e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR62464.1 - 7.4e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR62464.1 - 9.2e-05 21.6 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EMR62464.1 - 0.0023 17.9 0.1 0.0033 17.3 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR62464.1 - 0.0034 16.8 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMR62464.1 - 0.0094 15.1 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein F420_oxidored PF03807.17 EMR62464.1 - 0.14 12.7 0.1 1.2 9.8 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EMR62464.1 - 0.19 12.0 0.1 0.36 11.1 0.0 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ATG27 PF09451.10 EMR62465.1 - 1e-100 337.0 0.0 1.2e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 NRDD PF13597.6 EMR62465.1 - 0.3 9.8 0.1 0.4 9.4 0.1 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Ribosomal_L30 PF00327.20 EMR62466.1 - 3.2e-16 58.9 0.1 4e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.13 EMR62467.1 - 3.6e-61 206.0 0.1 5.2e-61 205.4 0.1 1.2 1 0 0 1 1 1 1 MRG BCDHK_Adom3 PF10436.9 EMR62468.1 - 5.1e-47 159.7 0.0 7.7e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EMR62468.1 - 2.7e-10 40.8 0.0 6.4e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chitin_synth_2 PF03142.15 EMR62469.1 - 5.8e-248 823.8 1.3 8.6e-248 823.2 1.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EMR62469.1 - 7e-73 246.0 0.0 2.3e-71 241.0 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EMR62469.1 - 2.3e-16 59.4 0.1 1e-15 57.3 0.2 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EMR62469.1 - 9.7e-13 48.1 0.5 3.7e-09 36.6 0.1 3.9 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EMR62469.1 - 1.2e-10 41.6 6.4 1.2e-10 41.6 6.4 2.3 2 1 0 2 2 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMR62469.1 - 6.3e-09 36.1 0.0 5.5e-08 33.0 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMR62469.1 - 2.7e-05 24.0 0.0 0.035 13.9 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 2 AAA_16 PF13191.6 EMR62469.1 - 0.011 16.2 0.2 0.061 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 EMR62469.1 - 0.028 13.9 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EMR62469.1 - 0.029 13.9 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMR62469.1 - 0.037 14.3 0.6 0.47 10.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain Glyco_transf_21 PF13506.6 EMR62469.1 - 0.061 12.8 0.2 0.36 10.3 0.2 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 21 AAA_29 PF13555.6 EMR62469.1 - 0.092 12.5 0.1 0.32 10.8 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 EMR62469.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 EMR62469.1 - 0.17 12.4 0.0 0.41 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Fungal_trans PF04082.18 EMR62470.1 - 8.8e-17 61.0 0.0 1.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR62470.1 - 1.7e-09 37.7 10.4 2.5e-09 37.1 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EMR62470.1 - 0.013 15.5 0.4 0.024 14.6 0.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EMR62470.1 - 0.084 12.5 2.9 0.15 11.6 2.9 1.3 1 0 0 1 1 1 0 Spt20 family Zip PF02535.22 EMR62471.1 - 5.3 6.1 4.8 6 6.0 4.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Chitin_synth_2 PF03142.15 EMR62472.1 - 1.9e-228 759.4 0.1 2.8e-228 758.8 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 EMR62472.1 - 3e-17 62.5 0.5 9.5e-11 41.7 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EMR62472.1 - 1.5e-15 56.8 0.2 9.7e-15 54.2 0.6 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EMR62472.1 - 2.4e-13 50.4 3.0 6e-13 49.2 3.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMR62472.1 - 3e-12 46.9 0.0 1.3e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 EMR62472.1 - 2.1e-08 32.9 0.0 1.4e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 EMR62472.1 - 0.00065 19.2 0.0 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EMR62472.1 - 0.0022 17.8 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Csm4_C PF17953.1 EMR62472.1 - 0.0052 16.6 0.1 4.7 7.1 0.0 2.7 2 0 0 2 2 2 2 CRISPR Csm4 C-terminal domain DASH_Ask1 PF08655.10 EMR62473.1 - 1.8e-30 104.6 0.2 3e-30 103.9 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 RIBIOP_C PF04950.12 EMR62474.1 - 5.7e-87 291.8 0.0 5.7e-87 291.8 0.0 2.2 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EMR62474.1 - 6.4e-28 96.7 0.0 1.6e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EMR62474.1 - 1.8e-05 25.0 0.0 4.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR62474.1 - 8.8e-05 22.9 0.0 0.00025 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMR62474.1 - 0.00026 21.5 0.3 0.038 14.5 0.0 3.4 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 EMR62474.1 - 0.00053 19.6 0.7 0.13 11.7 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EMR62474.1 - 0.00072 20.1 0.3 0.0035 17.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 EMR62474.1 - 0.00073 20.0 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EMR62474.1 - 0.00092 19.3 0.0 0.0029 17.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 EMR62474.1 - 0.0013 18.7 0.0 0.004 17.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 EMR62474.1 - 0.0021 18.2 0.6 0.0057 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EMR62474.1 - 0.0045 16.7 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EMR62474.1 - 0.0054 16.9 0.0 0.21 11.8 0.0 2.8 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EMR62474.1 - 0.006 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 EMR62474.1 - 0.0075 16.6 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMR62474.1 - 0.012 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR62474.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 EMR62474.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EMR62474.1 - 0.018 15.1 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EMR62474.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MobB PF03205.14 EMR62474.1 - 0.038 13.9 0.1 0.52 10.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 EMR62474.1 - 0.051 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 EMR62474.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EMR62474.1 - 0.074 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 EMR62474.1 - 0.097 12.7 0.1 0.32 11.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EMR62474.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_7 PF12775.7 EMR62474.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EMR62474.1 - 0.16 11.2 0.5 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Septin p450 PF00067.22 EMR62475.1 - 4.1e-44 151.1 0.0 4.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 EMR62477.1 - 7.5e-16 58.5 0.2 2.5e-15 56.9 0.2 1.7 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EMR62477.1 - 9.9e-05 21.9 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EMR62477.1 - 0.00012 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 EMR62477.1 - 0.12 12.3 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 EMR62477.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Inhibitor_I9 PF05922.16 EMR62478.1 - 3.3e-13 50.1 0.1 5e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ribosom_S12_S23 PF00164.25 EMR62479.1 - 8.3e-31 106.0 0.3 9.5e-31 105.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_N PF02771.16 EMR62480.1 - 4.6e-30 104.6 0.0 7.9e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EMR62480.1 - 1.8e-23 82.6 0.1 3.2e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 EMR62480.1 - 0.0069 16.1 0.1 0.017 14.8 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 EMR62480.1 - 0.023 14.7 0.1 0.079 13.0 0.0 1.9 2 0 0 2 2 2 0 Staphylococcal AgrD protein Acyl-CoA_dh_1 PF00441.24 EMR62480.1 - 0.059 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain PLDc_N PF13396.6 EMR62481.1 - 1.8e-12 47.0 3.7 1.8e-12 47.0 3.7 1.6 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal Tetraspanin PF00335.20 EMR62481.1 - 0.056 13.2 1.0 0.067 12.9 1.0 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2207 PF09972.9 EMR62481.1 - 0.1 11.4 1.1 0.11 11.3 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MSP1a PF11670.8 EMR62481.1 - 0.12 11.7 0.2 0.17 11.1 0.2 1.4 1 1 0 1 1 1 0 Major surface protein 1a (MSP1a) Glucos_trans_II PF14264.6 EMR62481.1 - 0.18 11.1 5.5 0.11 11.9 3.8 1.3 1 1 0 1 1 1 0 Glucosyl transferase GtrII ATP-synt_8 PF00895.20 EMR62481.1 - 1.5 9.4 0.0 1.5 9.4 0.0 2.5 2 1 1 3 3 3 0 ATP synthase protein 8 Glyco_hydro_18 PF00704.28 EMR62482.1 - 1.5e-67 228.5 5.6 2e-67 228.1 5.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short_C2 PF13561.6 EMR62483.1 - 3.9e-51 173.9 0.1 4.9e-51 173.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR62483.1 - 3.4e-46 157.2 0.3 4e-46 157.0 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR62483.1 - 1.4e-08 34.8 0.3 2.4e-08 34.1 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR62483.1 - 0.0039 16.7 0.2 0.0071 15.8 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR62483.1 - 0.024 13.6 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Esterase PF00756.20 EMR62484.1 - 1.2e-05 25.1 0.0 1.8e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EMR62484.1 - 0.00062 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 EMR62484.1 - 0.0088 15.6 0.4 0.021 14.3 0.2 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 EMR62484.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EMR62484.1 - 0.073 12.7 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 EMR62484.1 - 0.1 12.2 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Ribosomal_L7Ae PF01248.26 EMR62485.1 - 1.6e-21 75.8 0.7 2.6e-21 75.1 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EMR62485.1 - 0.0075 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 CLPTM1 PF05602.12 EMR62485.1 - 0.081 11.9 0.2 0.096 11.7 0.2 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MFS_1 PF07690.16 EMR62486.1 - 7.3e-21 74.5 61.8 3.6e-14 52.5 35.4 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR62486.1 - 2.3e-08 32.9 21.6 3.2e-08 32.5 21.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.26 EMR62487.1 - 2.6e-77 259.9 0.0 5.6e-77 258.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 EMR62487.1 - 1.4e-73 248.0 0.0 2.1e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EMR62487.1 - 2e-56 191.6 0.0 3.3e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 EMR62487.1 - 5.9e-48 163.6 0.0 9.7e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EMR62487.1 - 1.5e-46 158.6 0.0 1.9e-44 151.7 0.0 2.8 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EMR62487.1 - 5.3e-40 137.9 0.1 9.3e-40 137.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR62487.1 - 5.7e-31 107.0 0.0 1.6e-30 105.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EMR62487.1 - 1.4e-28 99.7 0.0 4.4e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 EMR62487.1 - 5.8e-19 68.2 0.3 1e-09 38.6 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EMR62487.1 - 1.7e-18 67.1 0.0 7.1e-18 65.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EMR62487.1 - 4.4e-16 59.3 0.0 2.6e-15 56.9 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EMR62487.1 - 7.6e-14 51.7 0.0 3.3e-08 33.3 0.0 2.7 3 0 0 3 3 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EMR62487.1 - 1.1e-10 41.6 0.0 3.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR62487.1 - 1.2e-10 41.9 0.0 5.2e-10 39.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR62487.1 - 4.4e-10 39.5 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR62487.1 - 3.1e-09 37.4 0.0 1.4e-08 35.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 EMR62487.1 - 4.8e-07 29.4 0.0 4.4e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EMR62487.1 - 2.1e-06 27.4 0.0 0.0031 17.0 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Methyltransf_16 PF10294.9 EMR62487.1 - 9.6e-06 25.4 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase 3Beta_HSD PF01073.19 EMR62487.1 - 1.5e-05 24.1 0.0 3.9e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 EMR62487.1 - 1.9e-05 24.1 0.1 3.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EMR62487.1 - 0.00072 19.0 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 EMR62487.1 - 0.0023 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 EMR62487.1 - 0.0059 16.9 0.0 9.2 6.5 0.0 3.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EMR62487.1 - 0.033 13.3 0.0 6 5.9 0.0 2.6 2 1 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 EMR62487.1 - 0.12 12.0 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.6 EMR62487.1 - 0.12 12.2 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 NAD(P)H-binding EF-hand_1 PF00036.32 EMR62488.1 - 3.4e-15 54.4 7.0 6.6e-05 22.2 0.4 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EMR62488.1 - 1.2e-14 54.5 0.7 7.2e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EMR62488.1 - 1.3e-13 49.7 4.9 0.00019 21.1 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EMR62488.1 - 1.3e-10 41.0 2.6 8.1e-07 28.8 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EMR62488.1 - 4.1e-08 32.4 4.6 0.084 12.4 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EMR62488.1 - 0.0012 19.1 0.1 0.0086 16.4 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain Caleosin PF05042.13 EMR62488.1 - 0.059 13.3 0.0 7.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein EF-hand_4 PF12763.7 EMR62488.1 - 0.063 13.2 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand FAD_binding_3 PF01494.19 EMR62489.1 - 2.6e-21 76.2 0.2 2.4e-12 46.8 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMR62489.1 - 4.3e-06 26.9 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR62489.1 - 1.1e-05 24.8 0.1 0.075 12.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR62489.1 - 0.0008 18.8 0.0 0.52 9.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR62489.1 - 0.00086 19.8 0.1 0.42 11.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR62489.1 - 0.0014 18.3 0.0 0.27 10.8 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EMR62489.1 - 0.0035 16.7 0.0 0.085 12.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EMR62489.1 - 0.0072 15.4 0.0 0.018 14.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 EMR62489.1 - 0.053 12.6 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Transketolase_N PF00456.21 EMR62490.1 - 2.5e-120 401.5 0.0 4.5e-120 400.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EMR62490.1 - 8.7e-35 120.0 0.0 2.1e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMR62490.1 - 3.7e-06 26.8 0.0 7.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EMR62490.1 - 7.8e-06 25.3 0.3 0.00016 21.0 0.1 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EMR62490.1 - 0.001 18.1 0.1 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component GSHPx PF00255.19 EMR62490.1 - 0.0015 18.1 0.1 0.25 10.9 0.0 2.6 2 0 0 2 2 2 1 Glutathione peroxidase AAA_22 PF13401.6 EMR62491.1 - 6.8e-06 26.4 0.1 0.00012 22.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMR62491.1 - 7.8e-06 25.9 0.0 2.6e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMR62491.1 - 0.00036 21.0 2.0 0.0019 18.6 0.0 2.7 2 2 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EMR62491.1 - 0.0093 15.2 0.0 0.031 13.5 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.6 EMR62491.1 - 0.011 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EMR62491.1 - 0.012 16.2 0.1 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 EMR62491.1 - 0.015 15.9 0.3 0.18 12.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EMR62491.1 - 0.021 15.2 0.0 6.6 7.2 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EMR62491.1 - 0.033 13.9 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EMR62491.1 - 0.042 13.6 0.5 0.091 12.5 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EMR62491.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EMR62491.1 - 0.053 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 EMR62491.1 - 0.056 13.8 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 EMR62491.1 - 0.091 12.4 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SesA PF17107.5 EMR62491.1 - 0.17 12.1 1.4 0.36 11.0 0.3 2.2 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Mto2_bdg PF12808.7 EMR62492.1 - 0.0045 17.3 2.1 0.01 16.1 2.1 1.6 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.15 EMR62492.1 - 0.032 14.0 0.4 0.071 12.9 0.4 1.5 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 EMR62492.1 - 0.098 13.1 0.6 0.26 11.8 0.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DUF5339 PF17274.2 EMR62492.1 - 0.1 13.5 0.0 0.25 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5339) APH PF01636.23 EMR62493.1 - 3.6e-18 66.4 0.1 3.6e-18 66.4 0.1 2.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family Astro_capsid_p PF12226.8 EMR62493.1 - 3.1 6.9 7.8 4.4 6.4 7.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein OCD_Mu_crystall PF02423.15 EMR62494.1 - 6.9e-11 41.6 0.2 5.7e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EMR62494.1 - 0.0019 18.3 0.0 3.3 7.8 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Arg_decarbox_C PF17944.1 EMR62494.1 - 0.019 15.5 0.2 7.6 7.2 0.1 2.6 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Ribosomal_60s PF00428.19 EMR62494.1 - 0.021 15.4 1.9 0.057 14.0 1.9 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mucin PF01456.17 EMR62494.1 - 0.13 12.3 8.6 0.27 11.2 8.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein ANAPC1 PF12859.7 EMR62494.1 - 2.3 8.8 6.4 6.5 7.3 6.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Thiolase_N PF00108.23 EMR62495.1 - 5.4e-74 248.8 0.9 7.3e-74 248.4 0.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMR62495.1 - 7.2e-43 145.2 0.1 1.4e-42 144.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMR62495.1 - 0.0036 16.9 2.1 0.022 14.3 0.6 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 EMR62495.1 - 0.083 13.1 0.0 0.31 11.2 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal An_peroxidase PF03098.15 EMR62496.1 - 3.6e-34 118.2 0.0 9.4e-25 87.2 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EMR62496.1 - 5.2e-05 22.2 0.0 0.00013 20.9 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 DEAD PF00270.29 EMR62497.1 - 1e-36 126.4 0.0 2.3e-36 125.2 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR62497.1 - 1.4e-22 80.1 0.0 3.3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMR62497.1 - 5.7e-20 71.3 0.0 1.2e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EMR62497.1 - 0.0042 17.1 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Phage_G PF02306.15 EMR62497.1 - 0.21 11.3 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 Major spike protein (G protein) Fungal_trans PF04082.18 EMR62498.1 - 1.2e-11 44.2 0.0 2.7e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2235 PF09994.9 EMR62499.1 - 1e-83 281.0 0.0 2.3e-83 279.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Cuticle_2 PF08184.11 EMR62499.1 - 0.15 12.1 1.3 0.34 10.9 1.3 1.6 1 0 0 1 1 1 0 Cuticle protein 7 isoform family Phage_CRI PF05144.14 EMR62500.1 - 0.063 12.6 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Phage replication protein CRI MetW PF07021.12 EMR62501.1 - 0.24 11.0 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Casein_kappa PF00997.18 EMR62501.1 - 2.7 8.1 6.8 4.8 7.3 6.8 1.4 1 0 0 1 1 1 0 Kappa casein MFS_1 PF07690.16 EMR62502.1 - 3e-42 144.8 43.7 3e-42 144.8 43.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR62502.1 - 7.9e-14 51.0 18.8 1.5e-13 50.0 18.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.25 EMR62503.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain DIOX_N PF14226.6 EMR62504.1 - 1.2e-30 106.7 0.0 2.4e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR62504.1 - 7e-17 61.8 0.0 1.3e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GFO_IDH_MocA PF01408.22 EMR62505.1 - 1.4e-18 67.9 0.0 2.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EMR62505.1 - 3.6e-05 24.2 0.0 7.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 EMR62505.1 - 0.00097 19.1 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.16 EMR62506.1 - 2.9e-19 69.2 23.6 4.6e-19 68.6 22.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily GerA PF03323.13 EMR62506.1 - 0.1 11.0 0.3 0.15 10.5 0.3 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Abhydrolase_6 PF12697.7 EMR62507.1 - 2.4e-05 25.0 0.0 0.0002 22.0 0.0 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR62507.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 EMR62507.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EMR62507.1 - 0.18 11.0 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zn-ribbon_14 PF16503.5 EMR62508.1 - 2.6e-18 65.2 4.9 2.6e-18 65.2 4.9 3.0 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 EMR62508.1 - 5.6e-10 39.3 0.0 8.2e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 EMR62508.1 - 0.0053 16.3 2.4 0.0067 16.0 0.5 2.0 2 0 0 2 2 2 1 RecR protein Birna_VP4 PF01768.16 EMR62508.1 - 0.017 14.9 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Birnavirus VP4 protein Mito_carr PF00153.27 EMR62509.1 - 2.2e-53 178.2 3.1 4.6e-19 68.1 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EMR62509.1 - 0.025 14.9 1.8 0.058 13.8 0.4 2.4 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Band_7 PF01145.25 EMR62510.1 - 7.9e-30 104.2 3.8 1.3e-29 103.5 3.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EMR62510.1 - 0.025 14.3 0.2 0.04 13.6 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family F-box-like PF12937.7 EMR62511.1 - 4.1e-05 23.4 0.1 0.00014 21.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR62511.1 - 0.0015 18.4 0.5 0.0065 16.3 0.4 2.2 2 0 0 2 2 2 1 F-box domain p450 PF00067.22 EMR62512.1 - 1e-23 83.8 0.0 3.1e-22 79.0 0.0 2.7 1 1 0 1 1 1 1 Cytochrome P450 DUF3732 PF12532.8 EMR62512.1 - 0.23 11.0 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) ADH_zinc_N PF00107.26 EMR62513.1 - 4.3e-10 39.7 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR62513.1 - 7.5e-08 32.2 0.2 4e-07 29.9 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Nup96 PF12110.8 EMR62514.1 - 1.4e-95 319.8 0.6 2.1e-95 319.2 0.6 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EMR62514.1 - 4.4e-49 166.4 0.0 7.4e-49 165.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EMR62514.1 - 8.3e-16 58.6 317.4 5.5e-07 30.4 40.6 10.6 3 3 6 9 9 9 6 Nucleoporin FG repeat region FAD_binding_4 PF01565.23 EMR62515.1 - 3.4e-16 59.2 0.7 5.7e-16 58.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.27 EMR62516.1 - 1.1e-52 175.9 2.0 4.5e-18 65.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 EMR62517.1 - 6.4e-22 77.3 3.8 1.4e-08 34.5 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Pex14_N PF04695.13 EMR62517.1 - 0.065 13.9 0.1 0.15 12.7 0.0 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5427 PF10310.9 EMR62517.1 - 7.1 5.5 10.1 7 5.5 6.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) APH PF01636.23 EMR62518.1 - 6.5e-08 32.8 0.1 0.00017 21.6 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMR62518.1 - 3.6e-05 23.5 0.0 0.018 14.6 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase Kdo PF06293.14 EMR62518.1 - 0.0039 16.6 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EMR62518.1 - 0.0055 16.1 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EMR62518.1 - 0.013 14.3 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 EMR62518.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_M28 PF04389.17 EMR62519.1 - 5e-34 117.7 0.0 8.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Pro_CA PF00484.19 EMR62520.1 - 3.8e-44 150.7 0.1 4.6e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ENTH PF01417.20 EMR62521.1 - 1.2e-47 161.0 0.1 1.9e-47 160.4 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF4264 PF14084.6 EMR62521.1 - 0.013 15.1 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) UIM PF02809.20 EMR62521.1 - 0.028 14.3 6.5 0.031 14.2 0.9 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif CD99L2 PF12301.8 EMR62521.1 - 0.031 14.6 1.3 0.089 13.1 1.3 1.8 1 0 0 1 1 1 0 CD99 antigen like protein 2 AAA PF00004.29 EMR62523.1 - 1.5e-10 41.6 0.0 4.5e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR62523.1 - 8e-06 26.3 0.0 1.5e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR62523.1 - 0.00084 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMR62523.1 - 0.0025 17.8 0.0 0.0093 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EMR62523.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EMR62523.1 - 0.06 13.1 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EMR62523.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain P5CR_dimer PF14748.6 EMR62524.1 - 2.2e-34 117.8 2.7 2.2e-34 117.8 2.7 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EMR62524.1 - 8.4e-20 71.2 0.7 8.4e-20 71.2 0.7 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EMR62524.1 - 6.6e-05 23.1 0.1 0.00012 22.3 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EMR62524.1 - 0.002 18.1 0.7 0.022 14.7 0.7 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 EMR62524.1 - 0.0037 17.3 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PDH PF02153.17 EMR62524.1 - 0.0061 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase IlvN PF07991.12 EMR62524.1 - 0.03 13.9 0.2 0.072 12.7 0.2 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 EMR62524.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNAD1 PF18744.1 EMR62526.1 - 0.017 15.0 0.6 0.017 15.0 0.6 1.6 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 1 DUF3447 PF11929.8 EMR62526.1 - 0.018 15.0 0.7 9.7 6.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Citrate_synt PF00285.21 EMR62527.1 - 3.3e-123 411.3 0.0 4.1e-123 411.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Beta-lactamase PF00144.24 EMR62528.1 - 1.6e-35 122.9 0.0 2e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EMR62528.1 - 0.13 11.9 0.0 0.83 9.2 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase enzyme family BUD22 PF09073.10 EMR62530.1 - 8.7e-97 325.2 45.0 1.5e-96 324.4 45.0 1.3 1 1 0 1 1 1 1 BUD22 Amidoligase_2 PF12224.8 EMR62531.1 - 9.7e-15 54.9 0.1 2.1e-13 50.5 0.1 2.2 2 1 0 2 2 2 2 Putative amidoligase enzyme Podoplanin PF05808.11 EMR62532.1 - 0.00057 20.0 0.0 0.00097 19.3 0.0 1.4 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.6 EMR62532.1 - 0.0028 16.6 0.0 0.0042 16.0 0.0 1.2 1 0 0 1 1 1 1 Amnionless Syndecan PF01034.20 EMR62532.1 - 0.0041 17.0 0.1 0.0095 15.8 0.1 1.6 1 0 0 1 1 1 1 Syndecan domain Lsm_interact PF05391.11 EMR62532.1 - 0.009 15.5 0.4 0.019 14.5 0.4 1.5 1 0 0 1 1 1 1 Lsm interaction motif EphA2_TM PF14575.6 EMR62532.1 - 0.02 15.7 0.0 0.12 13.2 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 EMR62532.1 - 0.023 13.6 0.3 0.031 13.2 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4448 PF14610.6 EMR62532.1 - 0.023 14.5 0.0 0.062 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) PMP1_2 PF08114.11 EMR62532.1 - 0.029 14.1 0.4 0.064 13.0 0.4 1.5 1 0 0 1 1 1 0 ATPase proteolipid family DUF4690 PF15756.5 EMR62532.1 - 0.033 14.8 0.1 0.083 13.5 0.1 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage SKG6 PF08693.10 EMR62532.1 - 0.036 13.5 0.9 0.036 13.5 0.9 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mid2 PF04478.12 EMR62532.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EMR62532.1 - 0.15 11.8 0.2 0.15 11.8 0.2 2.4 3 0 0 3 3 2 0 Adenovirus E3 region protein CR2 BTB PF00651.31 EMR62533.1 - 1.1e-14 54.6 0.0 2.4e-09 37.4 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain adh_short PF00106.25 EMR62534.1 - 2.2e-29 102.3 0.8 2e-28 99.2 0.8 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62534.1 - 4.7e-23 82.0 0.1 1.1e-20 74.2 0.1 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62534.1 - 3.2e-07 30.5 0.1 6.8e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 KR domain Herpes_capsid PF06112.11 EMR62535.1 - 0.33 11.0 10.0 0.41 10.7 10.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MOZ_SAS PF01853.18 EMR62536.1 - 2.6e-76 255.3 0.0 3.9e-76 254.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EMR62536.1 - 7.6e-22 76.7 1.9 1.5e-21 75.7 1.9 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 EMR62536.1 - 1.7e-07 31.2 2.5 6.9e-07 29.3 2.5 2.0 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EMR62536.1 - 0.013 15.4 3.4 0.013 15.4 3.4 2.3 2 0 0 2 2 2 0 PHD-finger Acetyltransf_7 PF13508.7 EMR62536.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MIF4G PF02854.19 EMR62538.1 - 5.7e-52 176.4 0.1 1.2e-51 175.3 0.1 1.6 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EMR62538.1 - 2.6e-23 82.0 0.1 2.6e-23 82.0 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.12 EMR62538.1 - 0.051 14.0 0.0 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain DUF1770 PF08589.10 EMR62539.1 - 2.6e-35 121.3 1.6 3.6e-35 120.9 1.6 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) E1_dh PF00676.20 EMR62540.1 - 1e-112 376.0 0.1 1.3e-112 375.7 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EMR62540.1 - 0.0028 16.9 0.1 0.005 16.1 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_pol_B PF00136.21 EMR62541.1 - 1.6e-116 389.7 0.1 2.4e-116 389.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EMR62541.1 - 1.2e-65 220.7 0.0 2.3e-65 219.8 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EMR62541.1 - 4.3e-37 128.0 0.0 8.8e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EMR62541.1 - 1.4e-25 89.1 9.5 1.4e-25 89.1 9.5 2.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EMR62541.1 - 0.0073 15.2 0.0 0.018 14.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral WHIM1 PF15612.6 EMR62542.1 - 1.7e-05 24.2 0.0 3.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PDT PF00800.18 EMR62543.1 - 1.8e-55 187.6 0.0 3.4e-55 186.7 0.0 1.4 1 1 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EMR62543.1 - 0.00025 20.7 0.0 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 ACT domain SPX PF03105.19 EMR62543.1 - 0.24 11.3 7.2 0.33 10.8 7.2 1.1 1 0 0 1 1 1 0 SPX domain Shisa PF13908.6 EMR62543.1 - 1.8 8.7 5.0 5.6 7.2 0.2 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator BES1_N PF05687.13 EMR62543.1 - 2.8 8.3 9.9 1.3 9.4 3.0 3.0 3 0 0 3 3 3 0 BES1/BZR1 plant transcription factor, N-terminal PPR_2 PF13041.6 EMR62544.1 - 1.5e-23 82.7 0.8 1.8e-13 50.5 0.0 4.2 4 1 1 5 5 5 3 PPR repeat family PPR_long PF17177.4 EMR62544.1 - 3.5e-09 36.3 3.3 4.6e-09 36.0 0.6 2.3 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EMR62544.1 - 1.7e-06 27.9 4.6 0.027 14.7 0.0 5.3 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 EMR62544.1 - 0.00011 22.2 0.6 0.11 12.6 0.3 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain ATP13 PF12921.7 EMR62544.1 - 0.0014 18.5 0.1 0.052 13.4 0.0 3.1 2 1 0 2 2 2 1 Mitochondrial ATPase expression PPR_1 PF12854.7 EMR62544.1 - 0.0016 18.1 2.4 8.4 6.2 0.3 5.1 5 0 0 5 5 5 1 PPR repeat MNE1 PF13762.6 EMR62544.1 - 0.1 12.6 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component TPR_6 PF13174.6 EMR62544.1 - 3.4 8.5 7.0 63 4.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat eRF1_2 PF03464.15 EMR62545.1 - 1.1e-47 161.7 0.1 1.8e-47 161.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EMR62545.1 - 1.3e-39 135.2 0.5 2.8e-39 134.1 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EMR62545.1 - 1.7e-21 76.6 0.0 2.7e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EMR62545.1 - 3.7e-11 43.4 0.3 2e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EMR62545.1 - 2.3e-09 37.6 0.0 3.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ribosomal_L7Ae PF01248.26 EMR62545.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Velvet PF11754.8 EMR62546.1 - 5.8e-39 134.5 0.1 2.3e-36 126.0 0.0 2.1 1 1 1 2 2 2 2 Velvet factor TPT PF03151.16 EMR62547.1 - 6.7e-24 84.7 8.2 7.5e-24 84.6 8.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EMR62547.1 - 7.7e-10 38.5 14.6 1e-09 38.1 14.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EMR62547.1 - 0.0043 17.2 24.4 0.024 14.8 0.9 2.8 2 1 0 2 2 2 2 EamA-like transporter family DNA_mis_repair PF01119.19 EMR62548.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMR62549.1 - 2.2e-55 187.2 0.0 3.4e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EMR62549.1 - 2.5e-29 101.8 0.0 1.1e-24 86.9 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EMR62549.1 - 3.8e-29 100.7 0.1 7.2e-29 99.8 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 EMR62549.1 - 0.044 14.0 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 EMR62549.1 - 0.05 13.7 0.1 17 5.5 0.0 3.3 2 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain 14-3-3 PF00244.20 EMR62549.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 14-3-3 protein DASH_Spc34 PF08657.10 EMR62550.1 - 5.6e-53 180.3 2.2 2.8e-28 99.4 0.3 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 CAP_N PF01213.19 EMR62550.1 - 0.028 13.9 2.2 0.043 13.3 2.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CRA PF06589.11 EMR62550.1 - 0.087 12.9 3.7 0.18 11.9 3.7 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) UL42 PF17638.2 EMR62550.1 - 0.15 12.0 2.5 0.13 12.2 1.0 1.6 2 0 0 2 2 2 0 HCMV UL42 DASH_Spc19 PF08287.11 EMR62550.1 - 0.24 11.3 4.5 0.38 10.6 4.5 1.4 1 0 0 1 1 1 0 Spc19 UPF0242 PF06785.11 EMR62550.1 - 0.46 10.6 3.5 0.69 10.0 3.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CDC27 PF09507.10 EMR62550.1 - 0.47 9.8 12.1 0.7 9.2 7.2 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Merozoite_SPAM PF07133.11 EMR62550.1 - 3.5 7.6 19.0 5.5 6.9 19.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF3176 PF11374.8 EMR62551.1 - 1.9e-29 102.0 0.6 1.9e-29 102.0 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Glyco_hydro_cc PF11790.8 EMR62552.1 - 3.9e-22 79.0 0.0 4.9e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NOA36 PF06524.12 EMR62552.1 - 2.3 7.5 8.2 2.8 7.2 8.2 1.1 1 0 0 1 1 1 0 NOA36 protein OPT PF03169.15 EMR62553.1 - 7.5e-102 342.0 27.1 2e-81 274.5 20.9 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Hce2 PF14856.6 EMR62554.1 - 3e-20 72.4 0.1 3.5e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor adh_short PF00106.25 EMR62555.1 - 8.4e-30 103.7 0.7 2.5e-29 102.1 0.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62555.1 - 9.6e-16 58.0 0.2 1.9e-15 57.1 0.2 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62555.1 - 8.9e-08 32.2 0.3 1.9e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 KR domain CBP_GIL PF10995.8 EMR62555.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis GIL BBE PF08031.12 EMR62557.1 - 1.5e-05 25.0 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EMR62557.1 - 0.00014 21.6 3.7 0.00022 21.0 3.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 EMR62557.1 - 0.069 12.8 0.3 3.7 7.1 0.3 2.5 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain Glyco_transf_22 PF03901.17 EMR62559.1 - 0.0027 17.0 1.7 0.0041 16.4 1.7 1.4 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family NrfD PF03916.14 EMR62559.1 - 0.068 12.8 6.9 0.059 13.0 5.6 1.4 1 1 0 1 1 1 0 Polysulphide reductase, NrfD Herpes_UL73 PF03554.13 EMR62559.1 - 0.74 9.9 6.0 1.9 8.6 6.0 1.6 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein Glyco_hydro_43 PF04616.14 EMR62561.1 - 1.7e-15 57.1 0.3 2.5e-15 56.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 EMR62561.1 - 6.9e-05 23.1 0.4 0.00016 21.9 0.1 1.8 2 0 0 2 2 2 1 Carbohydrate binding module (family 35) Glyco_hydro_32N PF00251.20 EMR62561.1 - 0.067 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain SET PF00856.28 EMR62562.1 - 2.4e-12 47.6 0.0 4.9e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EMR62562.1 - 1.9e-06 27.9 14.7 1.9e-06 27.9 14.7 2.6 2 1 0 2 2 2 1 MYND finger AadA_C PF18280.1 EMR62562.1 - 0.03 14.5 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside adenyltransferase C-terminal domain IL7 PF01415.16 EMR62562.1 - 0.2 11.7 1.8 0.4 10.7 1.8 1.5 1 0 0 1 1 1 0 Interleukin 7/9 family CpXC PF14353.6 EMR62562.1 - 0.54 10.3 6.0 0.28 11.2 0.1 2.5 2 0 0 2 2 2 0 CpXC protein RasGAP PF00616.19 EMR62563.1 - 8.7e-48 162.8 0.1 4.6e-47 160.4 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EMR62563.1 - 1.6e-29 102.8 6.2 1.6e-29 102.8 6.2 2.5 2 0 0 2 2 2 1 RasGAP C-terminus Pectinesterase PF01095.19 EMR62564.1 - 4.1e-13 48.7 0.0 5.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Pectinesterase DRAT PF07357.11 EMR62564.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) DSBA PF01323.20 EMR62567.1 - 2.1e-39 135.3 0.0 2.4e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EMR62567.1 - 0.00076 19.7 0.0 0.0014 18.8 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 EMR62567.1 - 0.01 15.8 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Phage-tail_1 PF09097.10 EMR62567.1 - 0.068 13.0 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 PTR2 PF00854.21 EMR62568.1 - 4.7e-47 160.7 0.2 6.2e-47 160.3 0.2 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EMR62568.1 - 0.82 8.5 13.2 0.022 13.7 5.9 2.0 2 1 0 2 2 2 0 Major Facilitator Superfamily NDUF_B12 PF08122.12 EMR62568.1 - 1.5 8.9 5.6 26 5.0 1.6 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family HET PF06985.11 EMR62569.1 - 1.4e-18 67.7 0.0 2.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) His_Phos_1 PF00300.22 EMR62570.1 - 5.9e-12 45.7 0.2 1.4e-11 44.4 0.2 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NTF2 PF02136.20 EMR62571.1 - 1.1e-31 109.9 0.2 1.2e-31 109.7 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Amidoligase_2 PF12224.8 EMR62572.1 - 1.6e-12 47.6 0.0 5e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme CAF1C_H4-bd PF12265.8 EMR62573.1 - 1.3e-13 51.0 0.0 3.9e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EMR62573.1 - 1.6e-11 44.6 8.4 3.2e-06 27.8 0.1 4.5 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR62573.1 - 4.2e-07 30.2 0.3 0.003 17.8 0.1 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR62573.1 - 0.039 12.6 0.7 0.84 8.2 0.3 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 IU_nuc_hydro PF01156.19 EMR62574.1 - 3.1e-16 59.8 0.0 4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase COesterase PF00135.28 EMR62575.1 - 1.1e-82 278.5 0.0 1.4e-82 278.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR62575.1 - 2.1e-05 24.5 2.4 0.00026 20.9 0.9 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Helicase_C PF00271.31 EMR62576.1 - 4.9e-14 52.6 0.0 1.2e-13 51.3 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EMR62576.1 - 2.3e-06 27.0 0.0 3.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 EMR62576.1 - 3.5e-05 23.7 10.6 7.1e-05 22.7 10.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EMR62576.1 - 6.5e-05 22.7 11.8 0.00017 21.4 11.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR62576.1 - 0.00054 19.9 6.2 0.0015 18.5 6.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EMR62576.1 - 0.00074 19.3 7.9 0.0021 17.8 7.9 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 EMR62576.1 - 0.014 15.7 8.3 0.014 15.7 8.3 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 EMR62576.1 - 0.029 14.2 12.5 0.11 12.3 12.5 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.6 EMR62576.1 - 0.082 13.4 0.1 0.43 11.1 0.1 2.2 1 0 0 1 1 1 0 Zinc-finger double domain Prok-RING_4 PF14447.6 EMR62576.1 - 0.13 12.1 8.4 0.36 10.7 8.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EMR62576.1 - 1.9 8.7 10.9 9 6.5 11.0 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Bradykinin PF06753.12 EMR62577.1 - 0.051 13.3 0.1 0.079 12.7 0.1 1.3 1 0 0 1 1 1 0 Bradykinin FA_desaturase PF00487.24 EMR62578.1 - 3.4e-23 82.8 28.3 5.7e-23 82.1 28.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EMR62578.1 - 4.9e-07 30.0 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Prok-RING_4 PF14447.6 EMR62579.1 - 0.00025 20.8 1.0 0.0037 17.1 0.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EMR62579.1 - 0.0024 17.9 3.6 0.0059 16.6 3.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMR62579.1 - 0.01 15.8 6.0 0.064 13.2 6.2 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMR62579.1 - 0.017 15.0 1.0 0.017 15.0 1.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ima1_N PF09779.9 EMR62579.1 - 0.02 15.8 0.1 0.028 15.3 0.1 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain zf-RING_2 PF13639.6 EMR62579.1 - 0.028 14.8 2.3 0.098 13.0 0.7 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 EMR62579.1 - 0.064 13.4 1.2 0.38 10.9 0.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 EMR62579.1 - 0.11 12.7 4.0 0.25 11.5 1.8 2.3 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 EMR62579.1 - 0.13 12.2 5.3 0.46 10.4 5.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EMR62579.1 - 0.4 10.7 5.2 5.5 7.0 1.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.21 EMR62579.1 - 0.64 10.2 5.0 2.6 8.2 5.0 2.0 1 1 0 1 1 1 0 FYVE zinc finger SNF2_N PF00176.23 EMR62581.1 - 9.9e-17 60.7 0.0 1.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EMR62581.1 - 0.00028 21.0 0.0 0.0014 18.6 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AIF_C PF14721.6 EMR62581.1 - 1.7 9.0 5.9 0.42 11.0 0.7 2.1 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term VCX_VCY PF15231.6 EMR62581.1 - 3.1 8.5 11.3 2 9.1 7.3 2.3 1 1 1 2 2 2 0 Variable charge X/Y family EthD PF07110.11 EMR62582.1 - 8.2e-06 26.9 0.0 1.1e-05 26.5 0.0 1.2 1 0 0 1 1 1 1 EthD domain Cpn60_TCP1 PF00118.24 EMR62583.1 - 6.4e-154 513.2 4.7 7.3e-154 513.0 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 EMR62583.1 - 0.019 14.2 0.4 0.052 12.8 0.4 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PNTB_4TM PF12769.7 EMR62583.1 - 0.026 15.0 0.1 0.61 10.6 0.0 2.6 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch FtsA PF14450.6 EMR62583.1 - 0.57 10.6 4.9 0.54 10.7 1.3 2.5 2 1 0 2 2 2 0 Cell division protein FtsA MFS_1 PF07690.16 EMR62584.1 - 6.4e-34 117.4 23.5 9.1e-34 116.9 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR62584.1 - 1.1e-06 27.9 12.3 1.8e-06 27.1 12.3 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TFIID_20kDa PF03847.13 EMR62585.1 - 4.6e-16 59.1 0.0 1.1e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EMR62585.1 - 0.00099 19.3 0.2 0.018 15.3 0.0 2.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone US2 PF02476.15 EMR62585.1 - 0.7 10.6 4.3 0.27 11.9 1.1 2.0 2 0 0 2 2 2 0 US2 family DUF3543 PF12063.8 EMR62585.1 - 0.8 9.0 6.4 0.24 10.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3543) MFS_1 PF07690.16 EMR62586.1 - 4.6e-33 114.6 26.7 8.5e-33 113.7 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MOZ_SAS PF01853.18 EMR62587.1 - 3.3e-52 176.8 0.0 1e-32 113.2 0.0 2.9 2 1 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 EMR62587.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EMR62587.1 - 0.046 14.2 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR62587.1 - 0.062 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Abhydrolase_1 PF00561.20 EMR62588.1 - 3.4e-14 53.1 0.0 9e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR62588.1 - 1e-06 29.5 2.1 2.9e-06 28.0 2.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR62588.1 - 9.3e-06 25.1 0.0 0.00065 19.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Nucleo_P87 PF07267.11 EMR62590.1 - 1.9 7.2 9.1 2.6 6.8 9.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MutS_V PF00488.21 EMR62591.1 - 2e-81 272.5 0.1 3.3e-81 271.8 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMR62591.1 - 1.7e-36 126.3 0.5 4.9e-36 124.8 0.5 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EMR62591.1 - 8.2e-25 87.7 0.7 2.6e-23 82.8 0.1 2.9 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 EMR62591.1 - 1.1e-17 64.3 0.0 7.3e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EMR62591.1 - 1.8e-17 63.4 3.9 4.4e-17 62.2 1.9 2.8 3 0 0 3 3 3 1 MutS family domain IV Serglycin PF04360.12 EMR62591.1 - 0.012 15.6 0.4 0.039 13.9 0.3 1.9 2 0 0 2 2 2 0 Serglycin Methyltransf_2 PF00891.18 EMR62592.1 - 2.2e-22 79.4 0.0 7.8e-22 77.6 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EMR62592.1 - 0.0035 18.0 0.0 0.028 15.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR62592.1 - 0.015 16.1 0.0 0.035 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Sigma70_r4_2 PF08281.12 EMR62592.1 - 0.041 13.6 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 EMR62592.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EMR62592.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r3 PF04539.16 EMR62592.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 GMC_oxred_C PF05199.13 EMR62593.1 - 3.7e-16 59.9 0.0 5.9e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Choline_kinase PF01633.20 EMR62594.1 - 0.0097 15.5 0.0 0.2 11.2 0.0 2.2 1 1 0 2 2 2 2 Choline/ethanolamine kinase tRNA_m1G_MT PF01746.21 EMR62595.1 - 1.5e-29 103.1 1.0 4.8e-19 68.8 0.0 2.5 3 0 0 3 3 3 2 tRNA (Guanine-1)-methyltransferase Auxin_canalis PF05703.11 EMR62595.1 - 3.2e-05 24.0 2.2 6.8e-05 22.9 2.2 1.5 1 0 0 1 1 1 1 Auxin canalisation Apt1 PF10351.9 EMR62595.1 - 0.063 12.1 3.7 0.1 11.5 3.7 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S30 PF01577.16 EMR62595.1 - 0.15 11.7 6.1 0.31 10.6 6.1 1.5 1 0 0 1 1 1 0 Potyvirus P1 protease ATP-synt_C PF00137.21 EMR62596.1 - 1.1e-10 41.6 12.5 1.1e-10 41.6 12.5 2.0 2 0 0 2 2 2 1 ATP synthase subunit C MFS_3 PF05977.13 EMR62596.1 - 0.065 11.6 7.8 0.6 8.4 0.1 2.0 1 1 1 2 2 2 0 Transmembrane secretion effector F-box-like PF12937.7 EMR62597.1 - 0.00017 21.4 0.5 0.00068 19.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like Rpn3_C PF08375.11 EMR62599.1 - 3.1e-26 91.6 2.5 9.4e-26 90.0 2.5 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EMR62599.1 - 1.2e-21 77.2 0.3 1e-20 74.2 0.0 2.6 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 EMR62599.1 - 0.026 14.6 0.1 0.097 12.8 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.6 EMR62600.1 - 5.2e-22 79.3 0.4 8.1e-22 78.7 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR62600.1 - 2.9e-16 59.6 0.2 4.9e-16 58.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ras PF00071.22 EMR62601.1 - 1.4e-58 197.1 0.3 1.6e-58 196.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR62601.1 - 3.2e-36 124.2 0.2 5.3e-36 123.5 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR62601.1 - 1.8e-15 56.8 0.1 2.2e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMR62601.1 - 2.8e-07 30.1 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMR62601.1 - 9.5e-07 28.5 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMR62601.1 - 2.2e-06 27.7 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR62601.1 - 1.9e-05 24.6 1.5 0.07 13.0 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EMR62601.1 - 0.035 14.5 0.1 0.069 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EMR62601.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EMR62601.1 - 0.1 12.9 0.0 5.4 7.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain GbpA_2 PF18416.1 EMR62601.1 - 0.13 12.6 1.0 5.9 7.2 1.0 2.3 1 1 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 G-alpha PF00503.20 EMR62601.1 - 0.17 11.0 0.4 3.2 6.8 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit KR PF08659.10 EMR62602.1 - 4.4e-22 78.9 0.0 1e-20 74.4 0.0 2.4 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EMR62602.1 - 8.2e-15 54.9 0.8 1.7e-14 53.9 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR62602.1 - 3.4e-06 28.2 0.1 1.3e-05 26.3 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR62602.1 - 0.00018 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 EMR62602.1 - 0.01 15.4 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase AlaDh_PNT_C PF01262.21 EMR62602.1 - 0.053 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EMR62602.1 - 0.079 12.4 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 short chain dehydrogenase Cupin_2 PF07883.11 EMR62603.1 - 6.3e-11 41.8 1.3 1.5e-05 24.6 0.1 2.9 2 1 1 3 3 3 2 Cupin domain Cupin_1 PF00190.22 EMR62603.1 - 2.8e-05 23.8 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EMR62603.1 - 0.0003 20.4 0.1 0.0026 17.4 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF861) 3-HAO PF06052.12 EMR62603.1 - 0.002 17.8 0.9 0.02 14.5 0.9 2.0 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Peptidase_S8 PF00082.22 EMR62606.1 - 1.3e-37 129.7 0.8 2e-37 129.1 0.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EMR62606.1 - 3e-27 94.4 1.9 6.6e-27 93.4 1.9 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 EMR62606.1 - 0.0055 17.4 0.2 0.017 15.8 0.2 1.8 1 0 0 1 1 1 1 Peptidase S8 pro-domain PepSY_TM PF03929.16 EMR62606.1 - 0.03 14.0 0.0 0.091 12.4 0.0 1.8 2 0 0 2 2 2 0 PepSY-associated TM region Pectate_lyase_3 PF12708.7 EMR62607.1 - 1.4e-08 34.9 2.5 7.4e-08 32.5 2.5 2.0 1 1 0 1 1 1 1 Pectate lyase superfamily protein DUF4955 PF16315.5 EMR62607.1 - 0.17 12.0 1.1 1.6 8.9 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4955) Gln_deamidase_2 PF18626.1 EMR62608.1 - 0.023 14.9 0.6 0.048 13.9 0.6 1.5 1 0 0 1 1 1 0 Glutaminase DUF1554 PF07588.11 EMR62608.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) MFS_1 PF07690.16 EMR62609.1 - 1.2e-36 126.4 28.9 1.2e-36 126.4 28.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.6 EMR62609.1 - 0.14 12.4 6.4 0.55 10.6 0.5 3.2 2 1 1 3 3 3 0 Stage V sporulation protein AB HSP20 PF00011.21 EMR62610.1 - 6.1e-19 68.1 0.1 3.8e-14 52.7 0.1 2.5 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EMR62610.1 - 3.8e-05 23.2 0.0 0.0083 15.7 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA AATase PF07247.12 EMR62612.1 - 1.1e-05 24.2 0.0 2.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 EMR62612.1 - 0.005 15.6 0.0 0.0081 14.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain BNR_2 PF13088.6 EMR62613.1 - 5.9e-05 22.5 0.0 0.0057 16.0 0.0 2.7 1 1 1 2 2 2 2 BNR repeat-like domain Sortilin-Vps10 PF15902.5 EMR62613.1 - 8.7e-05 21.5 0.4 0.059 12.2 0.1 3.1 3 1 0 4 4 4 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 EMR62613.1 - 0.00012 21.6 1.1 1.2 9.4 0.1 3.7 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_6 PF15899.5 EMR62613.1 - 0.15 12.2 0.0 5.4 7.4 0.0 2.6 2 0 0 2 2 2 0 BNR-Asp box repeat Sugar_tr PF00083.24 EMR62614.1 - 1.3e-83 281.4 26.8 1.5e-83 281.2 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR62614.1 - 7.1e-14 51.5 33.4 9.4e-12 44.5 29.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily CCDC-167 PF15188.6 EMR62614.1 - 0.19 12.1 0.2 3.3 8.1 0.0 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3328 PF11807.8 EMR62616.1 - 1.3e-25 90.5 0.9 1.5e-25 90.3 0.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_4 PF01565.23 EMR62617.1 - 7.8e-24 84.0 1.7 1.5e-23 83.1 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR62617.1 - 0.0022 18.1 0.1 0.0054 16.8 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ABC_tran PF00005.27 EMR62618.1 - 1.3e-35 122.9 0.2 7e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR62618.1 - 1.7e-16 60.7 0.7 1.7e-16 60.7 0.7 3.1 3 0 0 3 3 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EMR62618.1 - 3.4e-08 33.2 3.3 0.023 14.1 0.2 3.2 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMR62618.1 - 1.9e-07 31.4 0.1 0.0072 16.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EMR62618.1 - 1.2e-06 28.1 0.3 0.012 15.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EMR62618.1 - 2e-06 27.1 0.6 0.02 14.0 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 EMR62618.1 - 5.9e-06 26.5 1.5 0.0075 16.4 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 EMR62618.1 - 1.5e-05 25.6 0.2 0.17 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 EMR62618.1 - 1.5e-05 24.5 0.7 0.011 15.1 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 EMR62618.1 - 1.6e-05 24.0 2.0 0.044 12.7 0.0 2.5 3 0 0 3 3 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.6 EMR62618.1 - 2.3e-05 24.4 1.3 1 9.1 0.4 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EMR62618.1 - 2.9e-05 24.6 0.1 0.016 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EMR62618.1 - 4.5e-05 23.0 0.1 0.15 11.5 0.1 2.3 2 0 0 2 2 2 2 Poxvirus A32 protein RsgA_GTPase PF03193.16 EMR62618.1 - 5.3e-05 23.2 0.6 0.2 11.5 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EMR62618.1 - 6.3e-05 22.6 0.0 0.036 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EMR62618.1 - 0.00013 21.6 0.6 0.11 12.1 0.2 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EMR62618.1 - 0.00023 20.7 0.2 0.058 12.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EMR62618.1 - 0.0004 20.4 0.2 1.6 8.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase NTPase_1 PF03266.15 EMR62618.1 - 0.00041 20.3 1.7 0.14 12.1 0.0 3.2 3 0 0 3 3 3 1 NTPase AAA_33 PF13671.6 EMR62618.1 - 0.00075 19.7 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMR62618.1 - 0.00095 19.6 0.3 1.1 9.6 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_15 PF13175.6 EMR62618.1 - 0.0012 18.7 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ATP_bind_1 PF03029.17 EMR62618.1 - 0.0018 18.1 0.3 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 EMR62618.1 - 0.0019 18.1 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EMR62618.1 - 0.0025 18.2 0.2 1.9 8.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase ATPase_2 PF01637.18 EMR62618.1 - 0.0026 17.7 0.1 0.5 10.2 0.0 2.5 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EMR62618.1 - 0.0049 17.2 0.2 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EMR62618.1 - 0.0065 16.2 1.2 3.4 7.4 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein TsaE PF02367.17 EMR62618.1 - 0.0076 16.3 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EMR62618.1 - 0.0084 16.1 0.6 1.7 8.7 0.1 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 EMR62618.1 - 0.012 15.7 0.1 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA PF00004.29 EMR62618.1 - 0.013 16.0 0.2 1 9.8 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMR62618.1 - 0.013 15.2 0.2 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMR62618.1 - 0.016 15.2 2.6 2.4 8.1 0.1 2.8 3 0 0 3 3 2 0 NACHT domain DEAD PF00270.29 EMR62618.1 - 0.016 15.0 0.5 3.5 7.4 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase MobB PF03205.14 EMR62618.1 - 0.018 14.9 0.5 0.54 10.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 EMR62618.1 - 0.021 14.6 0.1 6 6.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EMR62618.1 - 0.024 14.4 0.2 7.2 6.3 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 EMR62618.1 - 0.042 13.9 0.2 36 4.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 EMR62618.1 - 0.067 12.9 0.4 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DnaB_C PF03796.15 EMR62618.1 - 0.069 12.5 0.0 0.81 9.0 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Septin PF00735.18 EMR62618.1 - 0.077 12.3 0.3 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Septin CLP1_P PF16575.5 EMR62618.1 - 0.077 12.8 0.1 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Roc PF08477.13 EMR62618.1 - 0.078 13.2 0.9 1.8 8.8 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 EMR62618.1 - 0.11 12.6 0.5 0.94 9.5 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP-synt_ab PF00006.25 EMR62618.1 - 0.11 12.2 0.1 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_PrkA PF08298.11 EMR62618.1 - 0.15 10.9 0.0 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain SRP54 PF00448.22 EMR62618.1 - 0.17 11.5 0.3 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 EMR62618.1 - 0.19 11.6 0.2 40 4.1 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain dNK PF01712.19 EMR62618.1 - 0.21 11.4 0.8 8.9 6.1 0.1 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase NB-ARC PF00931.22 EMR62618.1 - 0.47 9.6 4.7 15 4.6 2.0 2.8 2 1 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 EMR62618.1 - 1.1 8.5 7.2 2.2 7.5 0.0 3.5 4 0 0 4 4 4 0 KaiC HMG-CoA_red PF00368.18 EMR62619.1 - 1.5e-140 468.4 5.2 2e-140 468.0 5.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EMR62619.1 - 1e-46 158.6 0.8 1.9e-46 157.7 0.8 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EMR62619.1 - 2.6e-12 46.8 5.4 2.8e-10 40.2 5.4 2.5 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EMR62619.1 - 2.7e-07 29.1 2.2 2.7e-07 29.1 2.2 1.5 2 0 0 2 2 2 1 Patched family Mitofilin PF09731.9 EMR62620.1 - 5.6e-142 474.8 21.1 1.9e-139 466.4 21.1 2.3 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DUF4011 PF13195.6 EMR62620.1 - 0.18 11.7 0.8 0.38 10.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) V-ATPase_G_2 PF16999.5 EMR62620.1 - 0.62 10.5 10.7 2.5 8.5 10.7 2.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit FAM184 PF15665.5 EMR62620.1 - 8.5 6.1 15.1 1.4 8.6 11.2 1.7 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B p450 PF00067.22 EMR62622.1 - 1.3e-45 156.0 1.6 1.4e-34 119.7 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 ANP PF00212.18 EMR62622.1 - 0.12 12.6 0.3 0.3 11.3 0.3 1.7 1 0 0 1 1 1 0 Atrial natriuretic peptide Isochorismatase PF00857.20 EMR62624.1 - 7.4e-31 107.7 0.0 1.1e-30 107.0 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family FBA PF04300.13 EMR62624.1 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 F-box associated region Syja_N PF02383.18 EMR62625.1 - 1.3e-86 290.8 0.0 1.6e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FAD_binding_4 PF01565.23 EMR62626.1 - 3.7e-11 42.9 0.2 9.6e-11 41.6 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR62626.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like PikAIV_N PF18605.1 EMR62626.1 - 0.25 10.9 1.2 9.8 5.9 0.3 2.4 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Abhydrolase_3 PF07859.13 EMR62627.1 - 4.3e-26 92.1 0.1 5.3e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMR62627.1 - 3.3e-11 42.7 0.0 9.6e-11 41.1 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase Glyco_hydro_31 PF01055.26 EMR62628.1 - 6.2e-112 375.0 0.9 9.1e-112 374.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EMR62628.1 - 3.9e-05 23.9 0.9 0.00026 21.2 0.2 2.7 2 1 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 EMR62628.1 - 0.006 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) adh_short PF00106.25 EMR62629.1 - 1.9e-16 60.1 0.0 3.1e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62629.1 - 3.8e-09 36.4 0.0 6.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62629.1 - 4.3e-07 30.0 0.1 6.7e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 EMR62630.1 - 1.4e-32 113.0 0.0 2.1e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MR_MLE_C PF13378.6 EMR62631.1 - 4.6e-45 153.9 0.3 6.8e-45 153.3 0.3 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMR62631.1 - 0.00038 20.7 0.2 0.0034 17.6 0.2 2.3 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PPE PF00823.19 EMR62631.1 - 0.84 9.7 6.5 0.27 11.3 1.7 2.2 2 0 0 2 2 2 0 PPE family CFEM PF05730.11 EMR62632.1 - 1.4e-13 50.7 10.9 2.4e-13 49.9 10.9 1.4 1 0 0 1 1 1 1 CFEM domain DUF3852 PF12963.7 EMR62632.1 - 0.043 14.2 5.0 0.051 13.9 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3852) p450 PF00067.22 EMR62633.1 - 2.5e-68 230.9 0.0 3.3e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zip PF02535.22 EMR62634.1 - 3.9e-30 105.2 52.3 6.1e-15 55.3 7.7 3.9 2 1 2 5 5 5 3 ZIP Zinc transporter EMP70 PF02990.16 EMR62634.1 - 0.17 10.5 5.7 0.29 9.8 5.7 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 DUF1540 PF07561.11 EMR62634.1 - 5.9 7.3 6.0 11 6.4 2.3 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1540) Tannase PF07519.11 EMR62635.1 - 9.7e-92 308.3 0.0 1.1e-91 308.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EMR62635.1 - 0.00013 21.5 0.1 0.13 11.7 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EMR62635.1 - 0.14 11.4 0.0 0.59 9.3 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DPM3 PF08285.11 EMR62636.1 - 2.1 8.6 7.0 11 6.2 0.8 2.6 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Hydrophobin_2 PF06766.11 EMR62638.1 - 3.3e-31 107.0 9.7 4.9e-31 106.5 9.7 1.3 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.16 EMR62640.1 - 5.9e-37 127.4 32.8 6.9e-37 127.2 31.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2417 PF10329.9 EMR62640.1 - 0.22 10.9 4.4 16 4.8 4.9 2.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) JmjC PF02373.22 EMR62641.1 - 3.1e-10 40.5 0.2 1e-09 38.8 0.2 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EMR62641.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain eIF3_subunit PF08597.10 EMR62641.1 - 2.7 7.9 8.6 3.3 7.5 0.2 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Glyco_hydro_43 PF04616.14 EMR62642.1 - 5.2e-28 98.2 2.4 7e-28 97.8 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GatB_Yqey PF02637.18 EMR62643.1 - 0.039 13.8 0.7 0.083 12.8 0.5 1.7 1 1 1 2 2 2 0 GatB domain DUF1996 PF09362.10 EMR62644.1 - 2.7e-81 273.0 0.9 3.6e-81 272.6 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Asp PF00026.23 EMR62646.1 - 1.3e-72 244.9 7.7 1.6e-72 244.6 7.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR62646.1 - 5.4e-13 49.5 4.0 4.5e-11 43.3 2.6 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMR62646.1 - 0.00077 20.1 2.1 0.47 11.1 0.6 3.2 2 1 0 2 2 2 2 Aspartyl protease DEAD PF00270.29 EMR62647.1 - 1.1e-47 162.1 0.1 9.2e-47 159.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR62647.1 - 4.1e-22 78.6 0.1 4.1e-21 75.4 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EMR62647.1 - 0.021 13.6 0.7 2.1 7.0 0.0 3.1 1 1 3 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Cutinase PF01083.22 EMR62647.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Cutinase DUF2183 PF09949.9 EMR62648.1 - 4.3e-32 110.4 0.0 1e-31 109.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EMR62648.1 - 0.21 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Dioxygenase_C PF00775.21 EMR62650.1 - 0.0047 16.4 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Nucleos_tra2_C PF07662.13 EMR62651.1 - 5e-73 245.4 2.3 5e-73 245.4 2.3 2.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EMR62651.1 - 1.8e-20 73.3 4.3 1.8e-20 73.3 4.3 2.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus DUF2109 PF09882.9 EMR62651.1 - 2.2 8.4 8.7 0.64 10.1 0.3 3.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) dCMP_cyt_deam_1 PF00383.23 EMR62652.1 - 1.8e-08 34.1 0.0 3.7e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMR62652.1 - 8.1e-06 25.6 0.0 0.0001 22.1 0.0 2.1 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EMR62652.1 - 0.021 14.9 1.2 0.074 13.1 1.2 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase Fungal_trans PF04082.18 EMR62653.1 - 2.4e-05 23.5 0.7 4.1e-05 22.7 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cep3 PF16846.5 EMR62653.1 - 0.0072 14.8 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B DIOX_N PF14226.6 EMR62654.1 - 1e-19 71.4 0.0 2.6e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR62654.1 - 4.1e-16 59.3 0.0 7.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4998 PF16389.5 EMR62654.1 - 0.036 13.7 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function Nuf2 PF03800.14 EMR62654.1 - 0.14 12.3 0.0 6.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Nuf2 family Glyoxalase PF00903.25 EMR62655.1 - 1.3e-12 48.0 0.1 2.8e-12 47.0 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMR62655.1 - 1.2e-06 28.7 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMR62655.1 - 0.0051 17.6 0.0 0.016 16.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain TauD PF02668.16 EMR62657.1 - 2.9e-35 122.4 0.3 3.8e-35 122.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.19 EMR62658.1 - 1.9e-18 66.9 1.8 6.9e-18 65.0 1.8 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR62658.1 - 0.00089 19.4 0.1 0.0027 17.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMR62658.1 - 0.00095 19.2 1.2 0.0084 16.1 1.1 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EMR62658.1 - 0.0056 16.3 0.7 0.014 15.0 0.3 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR62658.1 - 0.019 14.0 1.2 1.3 8.0 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EMR62658.1 - 0.021 14.1 1.5 0.38 9.9 0.2 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EMR62658.1 - 0.082 11.9 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase adh_short PF00106.25 EMR62659.1 - 2.3e-38 131.6 0.6 2.9e-38 131.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62659.1 - 5.5e-29 101.4 0.1 7.1e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62659.1 - 2.5e-09 37.3 0.1 3.4e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR62659.1 - 6.5e-07 29.4 0.1 8.8e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR62659.1 - 0.00017 21.2 0.1 0.00024 20.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR62659.1 - 0.00038 20.0 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMR62659.1 - 0.0031 16.9 0.0 0.7 9.2 0.0 2.6 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 EMR62659.1 - 0.11 12.7 0.1 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EMR62659.1 - 0.21 10.9 0.0 0.38 10.1 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Brix PF04427.18 EMR62660.1 - 1.4e-48 165.6 0.0 1.9e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain Macoilin PF09726.9 EMR62660.1 - 0.075 11.6 5.1 0.098 11.2 5.1 1.2 1 0 0 1 1 1 0 Macoilin family CALM_bind PF16025.5 EMR62660.1 - 1.4 9.4 7.3 4.1 7.9 7.3 1.7 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Cwf_Cwc_15 PF04889.12 EMR62660.1 - 1.6 8.4 24.5 6 6.5 0.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Transp_cyt_pur PF02133.15 EMR62661.1 - 1e-73 248.7 26.8 8.4e-49 166.5 9.0 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.22 EMR62662.1 - 7.7e-30 104.0 0.1 3e-28 98.8 0.1 2.1 1 1 0 1 1 1 1 Cytochrome P450 DEAD PF00270.29 EMR62664.1 - 8.1e-47 159.2 0.0 1.2e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR62664.1 - 5.1e-31 107.3 0.0 6e-30 103.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR62664.1 - 4.4e-06 26.8 0.0 7.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EMR62664.1 - 0.098 12.3 0.0 2.7 7.6 0.0 2.2 1 1 1 2 2 2 0 SWI2/SNF2 ATPase TauD PF02668.16 EMR62665.1 - 7.2e-27 94.9 0.8 1.2e-26 94.1 0.8 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RrnaAD PF00398.20 EMR62667.1 - 0.3 10.1 0.0 0.49 9.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TALPID3 PF15324.6 EMR62667.1 - 9.7 3.7 10.4 14 3.2 10.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target GPP34 PF05719.11 EMR62669.1 - 1.5e-68 230.9 0.1 1.9e-68 230.5 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) HUN PF08729.10 EMR62670.1 - 4e-07 29.9 0.1 8.9e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Glyco_hydro_61 PF03443.14 EMR62671.1 - 9.5e-33 113.9 0.0 1.2e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 EMR62672.1 - 1e-43 149.6 38.9 2.7e-41 141.7 37.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR62672.1 - 3.2e-17 62.2 19.9 4.4e-17 61.7 19.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMR62672.1 - 2.3e-14 53.1 19.9 1.4e-13 50.5 5.0 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EMR62672.1 - 0.0044 15.9 5.1 0.0044 15.9 5.1 2.6 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 EMR62672.1 - 6.4 4.9 8.1 1.6 6.9 0.0 2.9 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_45 PF02015.16 EMR62673.1 - 6.1e-83 277.9 16.2 7.2e-83 277.7 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 NIF3 PF01784.18 EMR62674.1 - 3.4e-50 170.9 0.0 1.3e-49 169.1 0.0 1.7 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) F-box PF00646.33 EMR62675.1 - 3.1e-07 30.1 0.8 6.2e-07 29.1 0.8 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMR62675.1 - 0.00028 20.7 0.6 0.0005 19.9 0.6 1.4 1 0 0 1 1 1 1 F-box-like p450 PF00067.22 EMR62676.1 - 1.3e-50 172.5 0.0 3.4e-50 171.2 0.0 1.5 1 1 1 2 2 2 1 Cytochrome P450 FMO-like PF00743.19 EMR62677.1 - 1.2e-27 96.6 0.0 1.6e-15 56.5 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR62677.1 - 3.3e-13 49.6 0.3 1.3e-10 41.1 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR62677.1 - 6.2e-11 42.1 0.0 6.4e-10 38.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR62677.1 - 5.3e-08 32.4 1.4 4.7e-06 26.0 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMR62677.1 - 1.8e-06 28.0 0.5 3.7e-05 23.8 0.1 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMR62677.1 - 0.00014 22.0 0.0 0.00059 20.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR62677.1 - 0.0029 17.3 0.6 0.3 10.6 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR62677.1 - 0.012 14.9 0.3 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 EMR62677.1 - 0.035 14.2 0.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EMR62677.1 - 0.86 10.2 2.9 9.3 6.9 0.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase BolA PF01722.18 EMR62678.1 - 9.7e-20 70.6 0.0 2.6e-19 69.3 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein zf-C2H2_11 PF16622.5 EMR62678.1 - 0.034 13.9 0.2 0.82 9.5 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type adh_short PF00106.25 EMR62679.1 - 9.7e-27 93.7 0.0 9.8e-21 74.1 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62679.1 - 9.9e-18 64.5 0.0 1.5e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62679.1 - 1.2e-08 35.0 0.1 2.1e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR62679.1 - 0.0028 16.8 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMR62679.1 - 0.018 14.5 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR62679.1 - 0.06 12.7 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Asparaginase PF00710.20 EMR62681.1 - 6.3e-28 97.6 0.0 8.8e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EMR62681.1 - 4.5e-09 36.5 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain MFS_1 PF07690.16 EMR62683.1 - 3.6e-52 177.4 21.7 8.6e-48 163.0 8.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMR62683.1 - 1.3e-07 30.4 0.5 0.0014 17.0 2.4 2.6 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 EMR62683.1 - 0.00012 21.2 0.2 0.00012 21.2 0.2 2.7 3 1 0 3 3 3 1 PUCC protein BT1 PF03092.16 EMR62683.1 - 0.00021 19.6 0.4 0.00053 18.3 0.0 1.9 2 0 0 2 2 2 1 BT1 family MFS_4 PF06779.14 EMR62683.1 - 0.00025 20.5 12.8 0.0011 18.3 6.6 2.5 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EMR62683.1 - 5 5.9 17.0 0.089 11.6 6.5 2.8 2 1 0 3 3 3 0 MFS_1 like family Vps51 PF08700.11 EMR62684.1 - 1.2e-27 95.8 0.0 1.9e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 EMR62684.1 - 0.0026 16.5 0.2 0.0035 16.1 0.2 1.2 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 EMR62684.1 - 0.052 13.7 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 RPAP1_C PF08620.10 EMR62686.1 - 5.9e-26 90.4 0.0 1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EMR62686.1 - 6.8e-19 67.4 1.5 1.3e-18 66.5 1.5 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal DIT1_PvcA PF05141.12 EMR62687.1 - 1.2e-83 280.8 0.0 2e-43 148.9 0.0 2.1 1 1 1 2 2 2 2 Pyoverdine/dityrosine biosynthesis protein WW_1 PF18507.1 EMR62687.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 WW domain PALP PF00291.25 EMR62688.1 - 8.4e-33 114.0 0.0 2.1e-32 112.7 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 EMR62688.1 - 1.6e-06 28.6 0.0 4.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain CN_hydrolase PF00795.22 EMR62689.1 - 1.6e-36 126.0 0.0 2.1e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EMR62689.1 - 1.1e-25 90.2 0.0 5.2e-25 88.0 0.0 1.9 1 1 0 1 1 1 1 NAD synthase NAD_binding_4 PF07993.12 EMR62690.1 - 1.1e-33 116.5 0.0 1.7e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EMR62690.1 - 1.7e-10 40.8 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR62690.1 - 2.9e-05 24.3 0.0 8.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 EMR62690.1 - 0.00028 19.6 0.0 0.0052 15.4 0.0 2.2 1 1 1 2 2 2 1 AMP-binding enzyme 3Beta_HSD PF01073.19 EMR62690.1 - 0.0006 18.9 0.0 0.0017 17.4 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMR62690.1 - 0.00078 18.9 0.0 0.023 14.1 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMR62690.1 - 0.005 16.0 0.0 0.0092 15.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EMR62690.1 - 0.016 15.5 0.0 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EMR62690.1 - 0.036 14.0 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 KR domain MFS_1 PF07690.16 EMR62691.1 - 9.7e-19 67.5 30.2 1.5e-14 53.7 8.7 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily MgtC PF02308.16 EMR62691.1 - 0.0031 17.9 5.0 0.041 14.2 0.3 2.8 2 0 0 2 2 2 2 MgtC family Cation_ATPase_C PF00689.21 EMR62691.1 - 2.6 7.7 0.0 2.6 7.7 0.0 3.6 3 1 1 4 4 4 0 Cation transporting ATPase, C-terminus Polysacc_deac_1 PF01522.21 EMR62692.1 - 5.4e-28 97.4 0.0 7.1e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Abhydrolase_2 PF02230.16 EMR62693.1 - 0.00018 21.4 0.0 0.0004 20.2 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase RseA_C PF03873.13 EMR62693.1 - 0.54 10.5 8.2 0.094 13.0 3.2 2.2 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain FAD_binding_3 PF01494.19 EMR62695.1 - 3e-56 191.2 0.0 3.9e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR62695.1 - 1.7e-09 37.7 0.1 0.00028 20.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR62695.1 - 4.6e-06 25.6 0.0 0.012 14.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 EMR62695.1 - 0.00027 21.4 0.0 0.15 12.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR62695.1 - 0.0024 17.2 0.0 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR62695.1 - 0.0026 17.0 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EMR62695.1 - 0.0049 17.1 0.2 0.06 13.6 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR62695.1 - 0.012 14.8 0.0 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_1 PF00561.20 EMR62696.1 - 4.6e-20 72.3 0.0 1.4e-19 70.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EMR62696.1 - 5.8e-14 52.0 0.0 1.6e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_6 PF12697.7 EMR62696.1 - 0.013 16.1 1.7 0.085 13.4 1.9 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ank_2 PF12796.7 EMR62697.1 - 6.1e-16 58.8 0.4 5e-08 33.4 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR62697.1 - 8.2e-10 39.0 0.3 7.3e-07 29.6 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR62697.1 - 5.6e-05 23.2 0.2 0.0099 16.3 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EMR62697.1 - 0.00055 20.2 0.3 0.0073 16.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EMR62697.1 - 0.0018 18.7 0.2 0.0076 16.7 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat ADH_N PF08240.12 EMR62698.1 - 7.9e-27 93.3 4.3 1.7e-26 92.2 4.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR62698.1 - 1.6e-13 50.8 0.0 8.7e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMR62698.1 - 0.00076 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR62698.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_3 PF00202.21 EMR62699.1 - 5e-42 144.0 0.0 1e-41 143.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III RMI1_N PF08585.12 EMR62700.1 - 4.7e-56 190.0 0.0 6.1e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 RecQ mediated genome instability protein Menin PF05053.13 EMR62700.1 - 0.091 11.1 3.0 0.11 10.9 3.0 1.1 1 0 0 1 1 1 0 Menin GCD14 PF08704.10 EMR62700.1 - 0.23 11.1 0.3 0.35 10.5 0.3 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Secretin_N_2 PF07655.13 EMR62700.1 - 3.2 8.4 12.6 6.1 7.5 12.6 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Adaptin_N PF01602.20 EMR62701.1 - 7.1e-106 354.8 4.0 5.6e-94 315.6 1.4 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EMR62701.1 - 6.5e-54 182.3 2.7 4.3e-53 179.7 0.2 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMR62701.1 - 3.5e-14 52.9 0.4 2.7e-07 30.9 0.0 4.0 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.22 EMR62701.1 - 3.6e-09 36.1 3.6 0.0061 16.7 0.0 5.3 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EMR62701.1 - 0.002 18.6 0.0 1.2 9.7 0.0 3.8 3 0 0 3 3 3 1 HEAT-like repeat UNC45-central PF11701.8 EMR62701.1 - 0.0079 16.2 0.1 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 EMR62701.1 - 0.012 15.8 0.4 0.79 9.9 0.0 3.4 2 2 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 EMR62701.1 - 0.032 14.0 0.0 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 EMR62701.1 - 0.12 12.0 0.1 2.2 7.8 0.0 2.6 2 1 1 3 3 3 0 CLASP N terminal Bac_luciferase PF00296.20 EMR62703.1 - 1.5e-52 179.0 0.1 5.4e-52 177.2 0.1 1.8 1 1 1 2 2 2 1 Luciferase-like monooxygenase PAP2 PF01569.21 EMR62704.1 - 6.9e-27 93.9 0.6 6.9e-27 93.9 0.6 2.3 1 1 1 3 3 3 1 PAP2 superfamily DUF983 PF06170.12 EMR62704.1 - 0.56 10.7 7.0 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF1129 PF06570.11 EMR62704.1 - 6.3 6.2 6.1 25 4.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) MFS_1 PF07690.16 EMR62706.1 - 1.6e-20 73.3 41.7 1.6e-20 73.3 41.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EMR62707.1 - 2.3e-19 69.5 17.8 3.4e-10 39.4 8.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 EMR62707.1 - 0.00011 21.7 0.5 0.00017 21.0 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB SRP54 PF00448.22 EMR62708.1 - 1.1e-76 256.8 1.6 1.9e-76 256.1 1.6 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EMR62708.1 - 9e-31 106.4 3.2 9e-31 106.4 3.2 3.4 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 EMR62708.1 - 1.3e-17 63.8 0.1 4.1e-17 62.2 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EMR62708.1 - 8e-07 28.8 0.8 3.4e-06 26.8 0.8 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EMR62708.1 - 9.7e-07 29.0 0.0 3e-06 27.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 EMR62708.1 - 1.9e-05 25.1 1.8 2.7e-05 24.6 0.2 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EMR62708.1 - 0.00033 21.1 0.0 0.00065 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EMR62708.1 - 0.00097 18.9 0.1 0.0028 17.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EMR62708.1 - 0.001 18.4 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EMR62708.1 - 0.0017 18.9 0.0 0.0049 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EMR62708.1 - 0.0019 18.2 0.0 0.0071 16.4 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 EMR62708.1 - 0.0019 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase MMR_HSR1 PF01926.23 EMR62708.1 - 0.0025 17.9 0.2 0.08 13.0 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 EMR62708.1 - 0.0025 17.5 0.1 0.02 14.6 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase ATP_bind_1 PF03029.17 EMR62708.1 - 0.0028 17.5 0.4 0.048 13.4 0.1 2.6 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EMR62708.1 - 0.0029 16.6 3.6 0.0038 16.3 0.9 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EMR62708.1 - 0.0097 16.2 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EMR62708.1 - 0.0099 15.9 0.4 0.056 13.4 0.4 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EMR62708.1 - 0.013 15.8 0.1 0.036 14.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EMR62708.1 - 0.013 14.9 1.0 3.9 6.9 1.3 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 EMR62708.1 - 0.014 15.6 0.1 0.026 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 EMR62708.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 EMR62708.1 - 0.042 12.7 0.0 0.087 11.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain 6PF2K PF01591.18 EMR62708.1 - 0.045 13.0 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 EMR62708.1 - 0.083 12.3 0.0 0.3 10.5 0.0 1.9 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.29 EMR62708.1 - 0.098 13.1 0.4 0.39 11.1 0.4 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EMR62708.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Torsin Glyco_hydro_43 PF04616.14 EMR62709.1 - 5.1e-59 199.9 9.4 7.8e-51 173.1 2.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EMR62709.1 - 8.6e-10 38.7 2.1 0.00056 19.6 0.4 3.0 3 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain LysM PF01476.20 EMR62710.1 - 1.6e-07 31.3 0.0 0.011 15.8 0.0 3.5 3 0 0 3 3 3 2 LysM domain NLPC_P60 PF00877.19 EMR62710.1 - 0.012 15.6 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 NlpC/P60 family Pollen_allerg_2 PF01620.16 EMR62710.1 - 0.084 13.1 3.1 5.2 7.3 0.4 2.9 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) UPF0203 PF05254.12 EMR62710.1 - 0.088 13.1 0.1 0.088 13.1 0.1 3.1 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0203) SapB_2 PF03489.17 EMR62710.1 - 2.9 8.1 4.4 27 5.0 0.1 3.1 4 0 0 4 4 4 0 Saposin-like type B, region 2 HET PF06985.11 EMR62711.1 - 1.1e-15 58.2 0.0 2e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HYLS1_C PF15311.6 EMR62712.1 - 0.011 16.5 0.1 2.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus Pro_dh PF01619.18 EMR62713.1 - 4e-40 138.2 0.0 8.1e-40 137.2 0.0 1.4 1 1 0 1 1 1 1 Proline dehydrogenase TPM_phosphatase PF04536.14 EMR62713.1 - 0.026 14.7 0.2 0.078 13.1 0.0 1.8 2 0 0 2 2 2 0 TPM domain Aa_trans PF01490.18 EMR62714.1 - 4.8e-15 55.2 20.1 5e-10 38.7 11.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EMR62714.1 - 2.1e-05 23.8 9.8 2.1e-05 23.8 9.8 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aldedh PF00171.22 EMR62716.1 - 5.6e-87 292.2 0.0 6.7e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF PF00209.18 EMR62717.1 - 5.7e-75 253.0 29.3 1e-73 248.9 29.3 2.2 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3810 PF12725.7 EMR62717.1 - 0.13 11.6 1.1 0.33 10.3 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Dus PF01207.17 EMR62718.1 - 9.2e-55 185.9 0.0 2.9e-54 184.3 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) HDA2-3 PF11496.8 EMR62718.1 - 1.7 7.7 3.8 3.4 6.8 3.8 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 CDC45 PF02724.14 EMR62718.1 - 2.5 6.3 5.9 4.1 5.6 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein TPALS PF18178.1 EMR62719.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family adh_short_C2 PF13561.6 EMR62720.1 - 5.3e-45 153.8 0.0 6.7e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR62720.1 - 4.2e-33 114.5 0.0 5.3e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase GST_C PF00043.25 EMR62721.1 - 1.1e-08 35.1 0.0 2.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR62721.1 - 6e-08 32.9 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR62721.1 - 5.6e-05 23.5 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR62721.1 - 6.4e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR62721.1 - 6.8e-05 23.0 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMR62721.1 - 8.5e-05 22.8 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DNA_meth_N PF18284.1 EMR62721.1 - 0.073 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 DNA methylase N-terminal domain NAS PF03059.16 EMR62722.1 - 2.3e-60 204.3 0.0 2.8e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 EMR62722.1 - 2.2e-07 30.8 0.0 6.4e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR62722.1 - 0.078 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EMR62723.1 - 1.8e-24 86.2 0.0 2.6e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Rrf2 PF02082.20 EMR62723.1 - 0.13 12.7 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Dimerisation2 PF16864.5 EMR62723.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain TP_methylase PF00590.20 EMR62724.1 - 6.2e-42 144.0 5.1 1.1e-40 139.9 4.0 2.7 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EMR62724.1 - 4.5e-14 52.8 0.2 1.1e-12 48.3 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EMR62724.1 - 2.7e-11 42.7 0.0 6.7e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 EMR62724.1 - 8.8e-10 38.1 0.2 6.9e-09 35.2 0.1 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Abhydrolase_2 PF02230.16 EMR62725.1 - 1.6e-34 119.6 0.0 4.1e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EMR62725.1 - 3.5e-05 23.4 0.0 0.00015 21.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EMR62725.1 - 0.0002 21.3 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EMR62725.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EMR62725.1 - 0.21 10.8 0.2 21 4.3 0.0 2.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 NmrA PF05368.13 EMR62727.1 - 1.5e-14 54.2 0.0 1.7e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR62727.1 - 0.0011 18.8 0.0 0.056 13.3 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMR62727.1 - 0.0019 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 KR domain HemY_N PF07219.13 EMR62728.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.8 4 1 0 4 4 4 0 HemY protein N-terminus TFR_dimer PF04253.15 EMR62729.1 - 1.6e-34 118.6 0.1 2.7e-34 117.9 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EMR62729.1 - 3.4e-19 69.3 0.0 5.9e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMR62729.1 - 6.7e-09 35.7 0.1 4.8e-08 32.9 0.1 2.3 1 1 0 1 1 1 1 PA domain Pex26 PF07163.12 EMR62729.1 - 0.045 13.1 2.5 0.3 10.3 0.1 2.1 2 0 0 2 2 2 0 Pex26 protein PhyH PF05721.13 EMR62730.1 - 7.8e-35 121.0 0.0 9.8e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) BBE PF08031.12 EMR62730.1 - 0.063 13.4 0.1 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like DUF1479 PF07350.12 EMR62730.1 - 0.094 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AMP-binding PF00501.28 EMR62731.1 - 1.3e-100 337.0 0.0 2.3e-100 336.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EMR62731.1 - 1.3e-84 283.7 0.1 3.2e-84 282.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EMR62731.1 - 4.2e-61 206.0 0.3 6.2e-59 198.9 0.3 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EMR62731.1 - 1.9e-57 195.2 0.0 4.2e-57 194.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EMR62731.1 - 4e-49 167.1 0.0 3.7e-48 164.0 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EMR62731.1 - 2.4e-44 150.1 0.3 5.3e-44 149.0 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EMR62731.1 - 7.8e-23 80.6 0.1 3.9e-11 43.1 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EMR62731.1 - 1e-13 51.7 0.0 3.6e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EMR62731.1 - 1.6e-11 44.1 0.0 2e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EMR62731.1 - 2.2e-07 31.8 0.1 5e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 EMR62731.1 - 2.4e-06 27.1 0.2 5.8e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 EMR62731.1 - 4.8e-06 26.2 0.2 5.3e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EMR62731.1 - 1.2e-05 24.8 0.0 0.033 13.6 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMR62731.1 - 0.0014 18.3 0.3 0.71 9.4 0.0 2.5 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 EMR62731.1 - 0.024 13.6 0.0 6.2 5.7 0.0 2.5 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMR62731.1 - 0.044 12.9 0.0 0.51 9.4 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMR62731.1 - 0.16 11.9 0.7 0.67 9.8 0.1 2.4 3 0 0 3 3 2 0 NAD(P)H-binding RasGAP PF00616.19 EMR62732.1 - 9.4e-52 175.7 0.0 2.7e-51 174.2 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EMR62732.1 - 4.4e-48 162.9 2.9 1.8e-47 160.9 2.9 2.2 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 EMR62732.1 - 3e-30 101.1 37.5 0.0035 17.0 0.2 15.2 15 0 0 15 15 15 10 IQ calmodulin-binding motif CH PF00307.31 EMR62732.1 - 2.2e-10 40.7 0.0 6.7e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain RBD-FIP PF09457.10 EMR62732.1 - 1.9 8.5 7.7 78 3.3 0.0 4.6 5 0 0 5 5 5 0 FIP domain MFS_1 PF07690.16 EMR62733.1 - 1.6e-31 109.5 46.9 1.8e-25 89.6 11.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR62733.1 - 2.3e-11 43.3 4.1 2.3e-11 43.3 4.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Miga PF10265.9 EMR62733.1 - 0.18 10.7 1.5 0.25 10.3 1.5 1.1 1 0 0 1 1 1 0 Mitoguardin SR-25 PF10500.9 EMR62733.1 - 0.52 9.9 13.2 0.77 9.3 13.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 EMR62733.1 - 1 10.3 6.6 2 9.3 6.6 1.4 1 0 0 1 1 1 0 Chorion family 2 PI3K_1B_p101 PF10486.9 EMR62733.1 - 1.9 6.2 4.7 2.8 5.6 4.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 EMR62733.1 - 2.1 6.8 4.3 2.9 6.3 4.3 1.1 1 0 0 1 1 1 0 Macoilin family E1-E2_ATPase PF00122.20 EMR62734.1 - 2.4e-50 170.6 0.6 2.4e-50 170.6 0.6 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMR62734.1 - 7e-39 134.3 0.3 1.3e-38 133.4 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EMR62734.1 - 3.3e-19 69.1 0.0 9.6e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EMR62734.1 - 6.7e-06 26.0 3.3 0.00012 22.0 1.1 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMR62734.1 - 0.087 13.2 0.1 0.24 11.8 0.1 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 EMR62734.1 - 0.26 11.3 2.4 1.1 9.3 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) TctB PF07331.11 EMR62734.1 - 1.5 9.1 17.6 2.6 8.3 1.5 3.6 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Fungal_trans PF04082.18 EMR62735.1 - 2.2e-12 46.6 0.0 4.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SUIM_assoc PF16619.5 EMR62735.1 - 0.033 14.2 1.7 0.04 14.0 0.4 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA PF00004.29 EMR62736.1 - 4.8e-13 49.7 0.0 2.3e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR62736.1 - 0.0013 19.1 0.1 0.0034 17.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EMR62736.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMR62736.1 - 0.12 12.7 0.1 0.35 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain Cwf_Cwc_15 PF04889.12 EMR62736.1 - 0.73 9.5 8.2 1.2 8.8 8.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EMR62736.1 - 1.5 8.0 11.3 3 7.1 11.3 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 EMR62736.1 - 8.1 5.5 19.1 0.92 8.6 11.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) APH PF01636.23 EMR62737.1 - 3.7e-11 43.4 0.0 9.4e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EMR62737.1 - 0.012 14.4 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EMR62737.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EMR62737.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family IMPDH PF00478.25 EMR62738.1 - 1.3e-125 419.0 4.1 1.5e-125 418.8 4.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EMR62738.1 - 1.1e-12 48.1 0.1 4.5e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 EMR62738.1 - 6.3e-10 38.9 2.0 0.0011 18.4 0.0 2.7 3 0 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 EMR62738.1 - 1.5e-08 34.0 1.5 4.9e-08 32.4 0.5 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EMR62738.1 - 0.00011 21.8 2.5 0.0053 16.2 2.5 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EMR62738.1 - 0.0027 17.0 1.2 0.15 11.4 0.5 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG PK PF00224.21 EMR62738.1 - 0.053 12.4 0.0 0.17 10.7 0.0 1.7 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain YpsA PF06908.11 EMR62738.1 - 0.17 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family Gly_transf_sug PF04488.15 EMR62739.1 - 1.7e-17 63.8 0.0 2.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EMR62739.1 - 0.23 10.7 0.1 0.79 9.0 0.1 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain PAD PF03068.15 EMR62740.1 - 2e-111 372.8 0.0 2.9e-111 372.2 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) UPF0052 PF01933.18 EMR62741.1 - 1.9e-57 194.7 0.0 3.8e-56 190.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family UPF0052 CENP-B_dimeris PF09026.10 EMR62741.1 - 0.81 10.1 10.1 1.7 9.1 10.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GREB1 PF15782.5 EMR62742.1 - 8.4 3.4 9.9 11 2.9 9.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ldh_1_C PF02866.18 EMR62743.1 - 2.9e-46 157.5 0.0 7.4e-46 156.1 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EMR62743.1 - 1.4e-43 148.4 0.0 2.5e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMR62743.1 - 0.00026 20.1 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EMR62743.1 - 0.14 12.6 0.1 0.52 10.8 0.0 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GSH_synth_ATP PF03917.17 EMR62744.1 - 5.2e-115 384.2 0.0 5.9e-115 384.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EMR62744.1 - 5.4e-22 78.2 0.0 8.3e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase APH PF01636.23 EMR62745.1 - 0.00032 20.7 1.1 0.00032 20.7 1.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family LIP PF03583.14 EMR62746.1 - 3.8e-13 49.4 2.2 2e-06 27.4 2.3 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 EMR62746.1 - 5.8e-11 43.4 11.1 1e-10 42.6 11.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR62746.1 - 1.7e-08 34.0 0.0 2.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR62746.1 - 6.2e-08 32.6 0.2 2.5e-07 30.6 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR62746.1 - 0.00039 20.0 0.2 0.23 10.9 0.6 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EMR62746.1 - 0.0096 15.5 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Palm_thioest PF02089.15 EMR62746.1 - 0.036 13.9 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase HEAT PF02985.22 EMR62748.1 - 6.9e-17 60.1 10.0 0.0011 19.0 0.0 9.9 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 EMR62748.1 - 2.7e-11 43.7 6.0 9.2e-09 35.6 0.0 6.7 8 1 0 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.6 EMR62748.1 - 2.7e-10 40.5 6.3 0.00048 20.5 0.0 6.5 3 2 4 7 7 7 3 HEAT repeats IBN_N PF03810.19 EMR62748.1 - 4.7e-08 32.8 5.0 7.6e-08 32.2 3.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EMR62748.1 - 0.007 16.0 4.4 16 5.0 0.0 5.5 4 2 3 7 7 7 2 CLASP N terminal DUF3385 PF11865.8 EMR62748.1 - 0.014 15.3 3.6 1.8 8.4 0.0 4.8 4 3 1 5 5 5 0 Domain of unknown function (DUF3385) Arm PF00514.23 EMR62748.1 - 0.02 14.9 2.5 77 3.5 0.0 5.7 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DUF1548 PF07579.11 EMR62748.1 - 0.24 11.7 1.4 1.9 8.8 0.1 2.9 2 1 0 3 3 3 0 Domain of Unknown Function (DUF1548) DUF3347 PF11827.8 EMR62748.1 - 0.68 10.1 4.9 0.29 11.3 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) HMGL-like PF00682.19 EMR62749.1 - 6e-68 229.3 0.0 8.2e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EMR62749.1 - 6.1e-23 81.2 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ribosomal_S9 PF00380.19 EMR62750.1 - 2.5e-33 115.2 0.2 2.8e-33 115.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Lactate_perm PF02652.14 EMR62751.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.2 1 1 0 1 1 1 0 L-lactate permease DUF2834 PF11196.8 EMR62751.1 - 0.18 12.2 4.1 0.66 10.4 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2834) AAR2 PF05282.11 EMR62752.1 - 7e-72 242.7 0.0 8.4e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein SR-25 PF10500.9 EMR62752.1 - 0.019 14.6 0.3 0.019 14.6 0.3 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein S1 PF00575.23 EMR62753.1 - 2.5e-74 245.6 39.5 6.6e-13 48.8 0.4 12.5 13 0 0 13 13 13 10 S1 RNA binding domain S1_2 PF13509.6 EMR62753.1 - 0.00046 20.2 0.7 37 4.5 0.0 6.0 6 0 0 6 6 6 0 S1 domain TPR_14 PF13428.6 EMR62753.1 - 0.00054 20.6 8.3 6.5 7.9 0.0 5.7 2 2 4 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EMR62753.1 - 0.0021 17.2 0.6 0.011 14.9 0.3 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference RNase_II_C_S1 PF18614.1 EMR62753.1 - 0.0024 17.8 1.1 2.4 8.2 0.0 4.7 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain TPR_19 PF14559.6 EMR62753.1 - 0.006 17.1 6.3 3.4 8.3 0.3 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMR62753.1 - 0.013 15.8 0.5 2.3 8.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.14 EMR62753.1 - 0.05 13.6 10.0 0.047 13.7 0.3 3.5 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) TPR_6 PF13174.6 EMR62753.1 - 0.19 12.4 3.6 19 6.2 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Lactonase PF10282.9 EMR62754.1 - 0.00034 20.0 0.0 1.9 7.6 0.0 3.7 1 1 4 5 5 5 4 Lactonase, 7-bladed beta-propeller Methyltransf_16 PF10294.9 EMR62755.1 - 7.3e-29 100.7 0.0 1.4e-28 99.8 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EMR62755.1 - 1.2e-06 28.5 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR62755.1 - 0.054 13.0 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Apt1 PF10351.9 EMR62756.1 - 3e-203 676.0 1.7 3e-203 676.0 1.7 1.8 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EMR62756.1 - 2.8e-185 616.8 1.6 4.6e-185 616.1 1.6 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.9 EMR62756.1 - 5.8e-162 540.9 0.0 1.2e-161 539.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.9 EMR62756.1 - 1.3e-57 194.3 0.0 3.3e-57 193.0 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EMR62756.1 - 1.8e-38 131.9 0.0 5e-38 130.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EMR62756.1 - 3.1e-33 114.6 0.0 1.8e-32 112.1 0.0 2.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Serine_rich PF08824.10 EMR62756.1 - 0.073 13.1 0.9 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain EAP30 PF04157.16 EMR62757.1 - 1.3e-76 257.0 0.1 1.5e-76 256.8 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Acyl-CoA_dh_1 PF00441.24 EMR62758.1 - 2e-33 115.8 3.7 2e-33 115.8 3.7 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMR62758.1 - 1.9e-20 72.9 0.0 4.5e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMR62758.1 - 3.9e-20 72.6 1.2 1.2e-19 71.1 1.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMR62758.1 - 6.3e-14 52.4 4.4 6.3e-14 52.4 4.4 3.0 3 1 1 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain Sulfate_transp PF00916.20 EMR62759.1 - 1.1e-97 327.2 17.9 1.6e-97 326.7 17.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMR62759.1 - 1.1e-08 34.7 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EMR62759.1 - 0.016 15.5 2.1 0.099 13.0 0.1 2.6 2 0 0 2 2 2 0 STAS domain DUF1700 PF08006.11 EMR62759.1 - 0.41 10.2 8.8 1.8 8.0 4.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) ADH_N PF08240.12 EMR62760.1 - 8.9e-30 102.8 1.6 2.1e-29 101.6 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR62760.1 - 2.3e-14 53.5 0.0 3.4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR62760.1 - 1.7e-06 27.7 0.0 5.5e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMR62760.1 - 0.06 14.4 0.0 0.11 13.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR62760.1 - 0.089 12.1 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ATP-sulfurylase PF01747.17 EMR62761.1 - 2.8e-87 291.6 0.0 4.5e-87 291.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EMR62761.1 - 4.8e-56 189.0 0.0 7.9e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EMR62761.1 - 7.5e-55 184.9 0.0 1.2e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.6 EMR62761.1 - 0.16 12.5 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mucin PF01456.17 EMR62762.1 - 1e-05 25.5 10.3 2.6e-05 24.2 10.3 1.7 1 0 0 1 1 1 1 Mucin-like glycoprotein PAN_4 PF14295.6 EMR62762.1 - 0.0012 18.7 1.5 0.0021 17.9 1.5 1.4 1 0 0 1 1 1 1 PAN domain ODV-E18 PF10717.9 EMR62762.1 - 0.021 14.7 0.1 0.058 13.3 0.1 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4834 PF16118.5 EMR62762.1 - 0.21 12.6 0.9 4.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4179 PF13786.6 EMR62763.1 - 0.015 15.8 0.9 0.33 11.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF4604 PF15377.6 EMR62763.1 - 0.033 14.6 22.3 0.58 10.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) LCE PF14672.6 EMR62763.1 - 0.073 13.7 0.2 0.073 13.7 0.2 2.4 3 1 0 3 3 3 0 Late cornified envelope Ribosomal_60s PF00428.19 EMR62763.1 - 1.2 9.8 36.7 0.081 13.5 5.1 4.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein Ldh_1_C PF02866.18 EMR62764.1 - 3.8e-45 153.8 0.0 5.4e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EMR62764.1 - 2.4e-43 147.6 0.1 3.4e-43 147.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMR62764.1 - 0.008 15.2 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pectate_lyase_3 PF12708.7 EMR62765.1 - 3.7e-38 131.5 9.8 6.3e-30 104.6 4.0 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein Ribosomal_L28e PF01778.17 EMR62766.1 - 5.9e-36 123.7 0.2 8.2e-36 123.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.10 EMR62767.1 - 6.1e-46 154.9 0.0 7.1e-46 154.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Metal_resist PF13801.6 EMR62767.1 - 0.057 13.6 0.1 0.08 13.1 0.1 1.3 1 0 0 1 1 1 0 Heavy-metal resistance FA_hydroxylase PF04116.13 EMR62768.1 - 1.4e-23 83.7 19.9 1.8e-23 83.3 15.3 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.32 EMR62769.1 - 3.8e-60 198.4 10.8 4.4e-08 33.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR62769.1 - 2.8e-16 59.6 0.0 0.0022 18.2 0.0 5.8 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 EMR62769.1 - 1e-14 54.6 14.2 1.9e-14 53.7 14.2 1.5 1 1 0 1 1 1 1 Tup N-terminal Ge1_WD40 PF16529.5 EMR62769.1 - 2e-07 30.3 0.2 0.23 10.4 0.0 5.5 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EMR62769.1 - 4.5e-06 26.2 0.0 0.17 11.2 0.0 4.8 3 2 3 6 6 6 2 WD40-like domain Nup160 PF11715.8 EMR62769.1 - 0.00021 20.1 0.0 2.7 6.6 0.0 3.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 EMR62769.1 - 0.015 15.2 1.2 11 6.0 0.0 4.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EMR62769.1 - 0.024 13.2 0.3 0.42 9.1 0.1 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nbas_N PF15492.6 EMR62769.1 - 0.06 12.7 0.1 23 4.2 0.0 3.3 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 EMR62769.1 - 0.17 10.8 0.0 5.8 5.7 0.0 2.7 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Glyco_hydro_76 PF03663.14 EMR62770.1 - 2.8e-50 171.9 3.5 3.4e-50 171.6 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMR62770.1 - 0.00014 21.1 0.2 0.0073 15.4 0.0 2.3 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EMR62770.1 - 0.0016 17.0 0.0 0.72 8.3 0.0 2.2 1 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Ldi PF18566.1 EMR62770.1 - 0.031 13.8 0.4 0.084 12.3 0.5 1.7 2 0 0 2 2 2 0 Linalool dehydratase/isomerase SARAF PF06682.12 EMR62771.1 - 1.4e-91 307.6 2.0 1.7e-91 307.4 2.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis EGF_CA PF07645.15 EMR62771.1 - 0.04 14.1 1.0 0.083 13.1 1.0 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain Aminotran_3 PF00202.21 EMR62772.1 - 1.1e-115 386.5 0.0 1.3e-115 386.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ABC_membrane PF00664.23 EMR62773.1 - 1.4e-100 336.5 40.2 8e-52 176.6 14.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMR62773.1 - 1.4e-67 226.4 0.0 2e-33 115.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMR62773.1 - 1.8e-12 47.2 0.0 0.00018 21.0 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMR62773.1 - 3.9e-07 29.7 1.7 0.002 17.8 0.2 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMR62773.1 - 2.2e-06 27.7 0.1 0.14 12.0 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EMR62773.1 - 3.2e-06 27.6 2.9 0.031 14.7 0.1 3.2 2 2 1 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 EMR62773.1 - 2.2e-05 24.7 0.6 0.54 10.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EMR62773.1 - 3.6e-05 23.6 0.1 0.34 10.6 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 EMR62773.1 - 6.5e-05 21.9 2.9 0.065 12.0 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 EMR62773.1 - 0.00014 21.5 0.1 0.29 10.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EMR62773.1 - 0.0011 19.4 1.3 15 6.0 0.0 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EMR62773.1 - 0.0034 17.6 2.0 4.8 7.5 0.2 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EMR62773.1 - 0.0041 17.0 0.9 5.1 6.8 0.0 3.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EMR62773.1 - 0.0049 17.1 0.6 0.52 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EMR62773.1 - 0.0059 15.9 0.0 3.3 6.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin G-alpha PF00503.20 EMR62773.1 - 0.0086 15.3 0.0 3.7 6.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.14 EMR62773.1 - 0.013 15.5 0.7 13 5.8 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EMR62773.1 - 0.015 15.4 3.5 1.7 8.7 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 EMR62773.1 - 0.02 15.4 0.6 1.9 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EMR62773.1 - 0.026 14.7 0.1 13 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMR62773.1 - 0.028 15.0 0.0 9 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMR62773.1 - 0.029 13.9 0.1 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PRK PF00485.18 EMR62773.1 - 0.05 13.3 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 EMR62773.1 - 0.052 12.7 0.0 4.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 EMR62773.1 - 0.054 13.2 7.3 2.5 7.8 0.2 3.8 3 1 0 3 3 3 0 AAA domain Rad17 PF03215.15 EMR62773.1 - 0.073 13.0 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 EMR62773.1 - 0.12 12.1 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EMR62773.1 - 0.16 11.9 0.3 5 7.0 0.0 3.1 3 0 0 3 3 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 EMR62773.1 - 1.9 8.6 3.7 19 5.4 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase BRE1 PF08647.11 EMR62774.1 - 1.7e-24 85.7 6.7 1.7e-24 85.7 6.7 6.1 3 2 3 6 6 6 2 BRE1 E3 ubiquitin ligase PKcGMP_CC PF16808.5 EMR62774.1 - 0.28 11.1 4.1 2.1 8.3 0.1 4.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_1 PF00170.21 EMR62774.1 - 1.1 9.4 37.9 0.024 14.7 5.5 7.5 5 1 3 8 8 8 0 bZIP transcription factor DUF1664 PF07889.12 EMR62774.1 - 2.2 8.4 34.3 1.8 8.6 0.7 5.9 4 2 2 7 7 7 0 Protein of unknown function (DUF1664) Pectate_lyase_3 PF12708.7 EMR62775.1 - 5.1e-96 320.6 15.0 2e-81 273.0 11.0 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EMR62775.1 - 1.8e-06 27.5 1.3 0.033 13.9 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Serglycin PF04360.12 EMR62775.1 - 0.31 11.0 3.9 0.71 9.8 3.9 1.6 1 0 0 1 1 1 0 Serglycin CALCOCO1 PF07888.11 EMR62776.1 - 0.0063 15.4 9.0 0.0076 15.2 9.0 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 EMR62776.1 - 0.012 14.5 6.9 0.016 14.1 6.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein KASH_CCD PF14662.6 EMR62776.1 - 0.018 14.8 5.4 0.025 14.4 5.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Hid1 PF12722.7 EMR62776.1 - 0.11 10.5 1.2 0.14 10.2 1.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAS PF13851.6 EMR62776.1 - 0.19 11.1 7.1 0.27 10.6 7.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 EMR62776.1 - 0.33 11.0 10.4 0.47 10.5 10.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 EMR62776.1 - 1.2 8.3 4.2 1.6 7.9 4.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 EMR62776.1 - 1.4 9.5 11.5 0.24 12.1 4.0 2.6 1 1 1 2 2 2 0 SlyX Atg14 PF10186.9 EMR62776.1 - 5.8 5.9 7.8 8.4 5.4 7.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SRI PF08236.11 EMR62778.1 - 2.7e-22 78.7 12.5 6.5e-22 77.5 12.5 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EMR62778.1 - 4.9e-16 59.6 0.2 4.9e-16 59.6 0.2 4.3 3 2 0 3 3 3 1 SET domain AWS PF17907.1 EMR62778.1 - 1.4e-11 44.2 12.6 1.4e-11 44.2 12.6 2.4 2 0 0 2 2 2 1 AWS domain WW PF00397.26 EMR62778.1 - 0.00051 20.1 1.3 0.0012 18.9 1.3 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 EMR62778.1 - 0.0008 19.4 0.1 0.0028 17.6 0.1 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Myb_DNA-bind_7 PF15963.5 EMR62779.1 - 3.5e-23 81.3 0.3 6.5e-23 80.4 0.3 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EMR62779.1 - 1.5e-06 28.2 0.1 5.1e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR62779.1 - 0.019 15.2 0.2 0.05 13.9 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EMR62779.1 - 0.035 14.3 0.1 0.075 13.2 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Scs3p PF10261.9 EMR62781.1 - 2.4e-80 269.6 0.6 2.9e-80 269.3 0.6 1.0 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM XPC-binding PF09280.11 EMR62782.1 - 5.7e-25 86.8 15.4 8.9e-25 86.2 15.4 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EMR62782.1 - 2.6e-24 84.7 6.6 3e-13 49.4 0.5 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EMR62782.1 - 6.1e-21 73.9 0.3 1.1e-20 73.2 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EMR62782.1 - 1.8e-08 34.1 0.5 3.1e-08 33.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EMR62782.1 - 0.00097 18.9 0.0 0.46 10.3 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 EMR62782.1 - 0.013 15.6 0.0 0.032 14.3 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EMR62782.1 - 0.054 13.8 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 EMR62782.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 CUE domain DUF2407 PF10302.9 EMR62782.1 - 0.1 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MCM_N PF14551.6 EMR62782.1 - 0.15 12.7 0.2 0.4 11.3 0.2 1.7 1 0 0 1 1 1 0 MCM N-terminal domain Rib_recp_KP_reg PF05104.12 EMR62782.1 - 0.47 11.5 17.3 1.1 10.3 8.8 2.4 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Phosphodiest PF01663.22 EMR62783.1 - 1.7e-12 47.6 0.1 2.8e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMR62783.1 - 8.3e-05 22.1 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EMR62783.1 - 0.00063 19.2 0.2 0.0016 17.8 0.1 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily PglZ PF08665.12 EMR62783.1 - 0.17 11.9 2.2 10 6.2 0.5 2.4 2 0 0 2 2 2 0 PglZ domain DUF2427 PF10348.9 EMR62783.1 - 5.8 6.8 8.0 0.6 9.9 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) LTV PF04180.14 EMR62784.1 - 7e-128 427.6 11.9 8.2e-128 427.4 11.9 1.0 1 0 0 1 1 1 1 Low temperature viability protein M16C_assoc PF08367.11 EMR62785.1 - 1.1e-83 280.3 0.0 1.7e-83 279.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EMR62785.1 - 1.7e-33 116.2 0.0 2e-22 80.1 0.0 3.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMR62785.1 - 5.8e-08 32.8 0.0 2.2e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 EMR62785.1 - 0.065 13.3 1.0 0.19 11.8 0.1 2.1 2 0 0 2 2 2 0 UvrA interaction domain FlhC PF05280.11 EMR62786.1 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Aldo_ket_red PF00248.21 EMR62787.1 - 1.2e-51 175.7 0.0 3.6e-51 174.1 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family KR PF08659.10 EMR62788.1 - 5.9e-62 208.8 1.2 1.3e-61 207.7 0.4 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EMR62788.1 - 1.8e-52 178.8 0.0 3.4e-52 177.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EMR62788.1 - 2.9e-49 167.9 0.0 4.4e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EMR62788.1 - 2.4e-33 114.7 0.0 1.1e-32 112.6 0.0 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EMR62788.1 - 1.4e-25 90.3 0.0 3.9e-25 88.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 EMR62788.1 - 2.8e-20 72.8 0.0 1.1e-19 70.9 0.0 2.1 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EMR62788.1 - 1.6e-17 64.8 0.0 1.1e-16 62.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR62788.1 - 8.5e-17 61.3 0.4 2.8e-15 56.5 0.1 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR62788.1 - 2.9e-15 56.2 0.4 2.9e-15 56.2 0.4 2.7 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62788.1 - 6.2e-10 39.0 0.1 3.4e-09 36.6 0.2 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 EMR62788.1 - 1.5e-08 34.4 2.2 3.1e-08 33.4 0.2 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EMR62788.1 - 9.1e-06 25.9 1.7 2.5e-05 24.6 0.4 2.5 3 0 0 3 3 3 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 EMR62788.1 - 0.0019 17.4 0.0 0.0045 16.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein YjeF_N PF03853.15 EMR62788.1 - 0.0081 16.1 3.2 5.1 7.0 0.0 3.4 3 0 0 3 3 3 2 YjeF-related protein N-terminus Epimerase PF01370.21 EMR62788.1 - 0.013 15.0 0.7 0.72 9.3 0.1 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR62788.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMR62788.1 - 0.12 11.9 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 EMR62788.1 - 0.44 10.4 2.6 1.4 8.8 0.2 2.9 3 0 0 3 3 3 0 NAD(P)H-binding RelA_SpoT PF04607.17 EMR62789.1 - 0.0056 17.0 0.2 0.054 13.8 0.0 2.6 2 1 0 2 2 2 1 Region found in RelA / SpoT proteins Orn_Arg_deC_N PF02784.16 EMR62790.1 - 5.5e-83 278.1 0.0 7.4e-83 277.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EMR62790.1 - 6.7e-18 64.7 0.0 9.8e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain tRNA-synt_2 PF00152.20 EMR62791.1 - 1.7e-78 263.9 0.0 3.1e-78 263.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMR62791.1 - 0.00021 21.2 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF3506 PF12014.8 EMR62791.1 - 0.14 12.1 0.7 0.29 11.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Peptidase_M16_C PF05193.21 EMR62792.1 - 1.8e-24 86.8 0.0 4.9e-19 69.1 0.0 3.9 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMR62792.1 - 1e-06 28.8 0.0 6.7e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DDE_Tnp_IS1 PF03400.13 EMR62792.1 - 0.081 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 IS1 transposase PhetRS_B1 PF18262.1 EMR62792.1 - 0.78 10.0 4.0 2.4 8.4 4.0 1.8 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain M16C_assoc PF08367.11 EMR62792.1 - 1.1 8.3 7.4 11 5.0 7.4 2.3 1 1 0 1 1 1 0 Peptidase M16C associated Cu-oxidase_3 PF07732.15 EMR62793.1 - 9.7e-30 103.0 0.5 4.6e-29 100.8 0.1 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EMR62793.1 - 8.7e-26 90.9 0.0 2.9e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMR62793.1 - 1.4e-22 79.9 2.8 1.2e-18 67.2 0.1 3.4 2 1 0 2 2 2 2 Multicopper oxidase adh_short PF00106.25 EMR62794.1 - 3.7e-06 26.6 0.1 9e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62794.1 - 0.00023 20.8 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62794.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 KR domain Sulfotransfer_3 PF13469.6 EMR62794.1 - 0.009 16.4 0.1 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family NAD_binding_10 PF13460.6 EMR62794.1 - 0.011 15.6 0.0 0.048 13.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_4 PF07993.12 EMR62794.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Taxilin PF09728.9 EMR62795.1 - 2e-82 276.8 60.0 2e-55 188.2 41.6 2.3 2 0 0 2 2 2 2 Myosin-like coiled-coil protein DUF4239 PF14023.6 EMR62795.1 - 0.00025 20.8 0.2 0.014 15.2 0.0 2.7 1 1 1 3 3 3 1 Protein of unknown function (DUF4239) KASH_CCD PF14662.6 EMR62795.1 - 0.00067 19.5 3.7 0.00067 19.5 3.7 3.9 2 1 2 4 4 4 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 EMR62795.1 - 0.0021 18.1 6.5 0.0021 18.1 6.5 4.7 2 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EMR62795.1 - 0.0062 17.1 2.1 0.0062 17.1 2.1 4.7 3 1 2 5 5 5 1 Apg6 coiled-coil region GAS PF13851.6 EMR62795.1 - 0.0089 15.4 8.0 0.0089 15.4 8.0 4.1 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 EMR62795.1 - 0.92 9.8 50.8 0.24 11.6 3.7 4.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 EMR62795.1 - 3.3 7.7 35.4 3.2 7.8 0.9 4.4 3 1 1 4 4 4 0 Laminin Domain II ABC_membrane PF00664.23 EMR62796.1 - 6.5e-23 81.8 9.0 8.9e-23 81.3 9.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region FHA PF00498.26 EMR62797.1 - 4e-08 33.5 0.1 7.5e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.25 EMR62797.1 - 9.3e-06 25.2 0.0 3.7e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Yop-YscD_cpl PF16697.5 EMR62797.1 - 0.0031 17.8 0.0 0.0059 16.9 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ILVD_EDD PF00920.21 EMR62798.1 - 1.1e-215 717.2 0.3 1.3e-215 716.9 0.3 1.1 1 0 0 1 1 1 1 Dehydratase family GTP_EFTU_D4 PF14578.6 EMR62798.1 - 0.94 9.4 6.6 3.8 7.5 0.1 3.8 4 0 0 4 4 4 0 Elongation factor Tu domain 4 NMT1 PF09084.11 EMR62799.1 - 0.00019 21.4 0.0 0.005 16.8 0.0 2.3 1 1 1 2 2 2 2 NMT1/THI5 like Phosphonate-bd PF12974.7 EMR62799.1 - 0.00041 20.0 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EMR62799.1 - 0.004 16.6 0.0 0.031 13.7 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 EMR62799.1 - 0.046 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family adh_short PF00106.25 EMR62800.1 - 1.9e-47 161.2 0.6 2.3e-47 161.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62800.1 - 4.2e-44 150.9 0.2 5.1e-44 150.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62800.1 - 6.9e-06 26.1 0.1 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMR62800.1 - 0.00012 22.0 0.1 0.00028 20.8 0.1 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 EMR62800.1 - 0.0017 18.2 0.2 0.0037 17.1 0.2 1.6 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 EMR62800.1 - 0.0041 16.6 0.1 0.014 14.9 0.0 1.9 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMR62800.1 - 0.0086 15.2 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EMR62800.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 EMR62800.1 - 0.014 14.8 0.1 0.037 13.3 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 EMR62800.1 - 0.042 13.0 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_25 PF13649.6 EMR62800.1 - 0.043 14.5 0.2 0.099 13.4 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_7 PF13241.6 EMR62800.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Abhydrolase_3 PF07859.13 EMR62801.1 - 1e-08 35.3 0.0 1.8e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_2 PF00891.18 EMR62802.1 - 8.9e-21 74.1 0.0 1.4e-20 73.5 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase domain Glyco_hydro_31 PF01055.26 EMR62803.1 - 9.3e-140 466.7 2.6 1.4e-139 466.1 2.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EMR62803.1 - 1.3e-23 83.1 0.3 5e-23 81.2 0.3 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EMR62803.1 - 7.5e-07 29.3 0.6 2.5e-06 27.6 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NDK PF00334.19 EMR62804.1 - 6.4e-53 178.4 0.0 7.3e-53 178.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_tran_28_C PF04101.16 EMR62805.1 - 1.2e-08 35.1 0.1 1.7e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 EMR62805.1 - 2.4e-08 33.3 0.0 4.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Zn_clus PF00172.18 EMR62806.1 - 3.4e-10 39.9 10.4 3.4e-10 39.9 10.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR62806.1 - 1.1e-05 24.6 4.2 4.4e-05 22.7 4.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain MinE PF03776.14 EMR62806.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE FLILHELTA PF10306.9 EMR62807.1 - 1e-25 89.9 0.0 1.8e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EMR62807.1 - 0.021 15.4 0.0 0.042 14.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) GatD_N PF18195.1 EMR62807.1 - 0.093 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 GatD N-terminal domain MMR_HSR1 PF01926.23 EMR62808.1 - 1e-16 61.0 0.2 3.5e-15 56.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMR62808.1 - 1.5e-07 31.1 0.3 7e-06 25.7 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMR62808.1 - 4.9e-05 23.3 0.1 0.0033 17.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EMR62808.1 - 0.0034 17.5 1.1 0.16 12.0 0.4 2.7 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.16 EMR62808.1 - 0.0034 16.7 0.1 0.0061 15.9 0.1 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EMR62809.1 - 0.00011 22.3 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_29 PF03141.16 EMR62809.1 - 0.043 12.4 0.0 0.073 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Dynamin_N PF00350.23 EMR62809.1 - 0.35 10.9 0.0 0.35 10.9 0.0 2.8 2 2 1 3 3 3 0 Dynamin family PIEZO PF15917.5 EMR62809.1 - 2.6 7.5 9.6 5.3 6.4 9.6 1.5 1 0 0 1 1 1 0 Piezo Phytase PF02333.15 EMR62810.1 - 7.6e-40 137.0 8.4 4.7e-35 121.3 1.1 3.1 2 1 1 3 3 3 3 Phytase EGF_2 PF07974.13 EMR62810.1 - 0.076 13.4 6.8 0.15 12.5 6.8 1.5 1 0 0 1 1 1 0 EGF-like domain SBDS PF01172.18 EMR62810.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Hydrolase_6 PF13344.6 EMR62811.1 - 5.4e-22 77.8 0.0 1e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR62811.1 - 2e-19 69.4 0.0 4.7e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EMR62811.1 - 0.012 16.0 0.0 5.3 7.3 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR62811.1 - 0.021 14.9 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EMR62811.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Cupin_2 PF07883.11 EMR62812.1 - 0.00045 19.9 0.1 0.0016 18.1 0.0 1.9 2 0 0 2 2 2 1 Cupin domain DUF4390 PF14334.6 EMR62812.1 - 0.055 12.9 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) Kinesin PF00225.23 EMR62814.1 - 6.5e-87 291.6 0.1 1.3e-86 290.6 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMR62814.1 - 4.7e-45 153.2 0.7 1.2e-44 151.8 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding Tropomyosin PF00261.20 EMR62814.1 - 0.059 12.7 55.1 0.046 13.1 44.9 3.7 1 1 2 3 3 3 0 Tropomyosin AAA_22 PF13401.6 EMR62814.1 - 0.06 13.6 0.0 0.06 13.6 0.0 3.8 2 1 2 4 4 4 0 AAA domain Laminin_II PF06009.12 EMR62814.1 - 0.083 12.9 26.8 0.45 10.5 11.7 3.9 1 1 3 4 4 4 0 Laminin Domain II AdoHcyase_NAD PF00670.21 EMR62814.1 - 0.099 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AAA_16 PF13191.6 EMR62814.1 - 0.18 12.2 0.0 0.18 12.2 0.0 3.5 2 1 0 2 2 1 0 AAA ATPase domain DUF948 PF06103.11 EMR62814.1 - 0.47 10.7 12.0 1.2 9.4 0.7 3.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EMR62814.1 - 5.1 7.1 24.0 1.6 8.8 7.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EMR62814.1 - 6.5 5.5 54.9 6 5.6 11.2 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein DEAD PF00270.29 EMR62814.1 - 6.9 6.4 7.9 15 5.3 1.4 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase MFS_1 PF07690.16 EMR62815.1 - 2.9e-46 158.0 49.3 9.9e-46 156.3 49.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR62815.1 - 2e-08 33.2 22.4 2.9e-08 32.6 22.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EXS PF03124.14 EMR62815.1 - 0.013 14.9 4.0 0.024 14.0 1.4 2.4 1 1 2 3 3 3 0 EXS family Cerato-platanin PF07249.12 EMR62817.1 - 0.00036 20.6 0.1 0.00036 20.6 0.1 2.3 2 1 1 3 3 3 1 Cerato-platanin Pyridoxal_deC PF00282.19 EMR62818.1 - 2.6e-102 342.3 0.0 3.1e-102 342.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain EIF_2_alpha PF07541.12 EMR62819.1 - 1.3e-35 121.9 0.0 2.3e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EMR62819.1 - 7.5e-14 51.8 0.7 1.5e-13 50.8 0.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Ras PF00071.22 EMR62820.1 - 1.5e-64 216.5 0.0 1.9e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR62820.1 - 7.7e-34 116.5 0.1 1.4e-33 115.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR62820.1 - 2.8e-13 49.7 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMR62820.1 - 1.7e-05 24.4 0.0 3.3e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMR62820.1 - 0.00035 20.0 0.0 0.0005 19.5 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMR62820.1 - 0.00076 19.6 0.1 0.0063 16.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR62820.1 - 0.0014 18.5 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EMR62820.1 - 0.039 13.5 0.0 0.2 11.2 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NCA2 PF08637.10 EMR62821.1 - 2.9e-115 384.4 0.6 5e-115 383.6 0.1 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 RuvC PF02075.17 EMR62822.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC MOR2-PAG1_C PF14225.6 EMR62822.1 - 0.11 12.3 0.1 16 5.3 0.0 2.8 3 0 0 3 3 3 0 Cell morphogenesis C-terminal DUF3671 PF12420.8 EMR62823.1 - 0.2 11.8 0.0 0.26 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function SE PF08491.10 EMR62825.1 - 1.1e-83 280.4 0.0 1.6e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EMR62825.1 - 1.3e-11 44.4 0.2 4.6e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EMR62825.1 - 4.4e-09 36.4 0.9 1.8e-07 31.0 0.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR62825.1 - 5.6e-05 23.3 0.3 0.00013 22.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR62825.1 - 0.00013 21.3 0.0 0.00037 19.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EMR62825.1 - 0.00016 20.9 0.1 0.00031 20.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EMR62825.1 - 0.0002 20.6 0.6 0.001 18.2 0.6 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMR62825.1 - 0.00033 20.1 0.0 0.00093 18.6 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR62825.1 - 0.0011 19.5 0.1 0.0026 18.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR62825.1 - 0.0013 18.1 0.1 0.0019 17.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMR62825.1 - 0.0018 18.2 0.1 0.0029 17.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EMR62825.1 - 0.0025 17.5 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EMR62825.1 - 0.0048 16.9 0.0 0.0079 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 EMR62825.1 - 0.0093 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 EMR62825.1 - 0.021 13.9 0.4 0.046 12.8 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 EMR62825.1 - 0.08 11.6 0.2 0.12 11.0 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EMR62825.1 - 0.087 12.1 0.1 0.16 11.2 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EMR62825.1 - 0.089 12.1 0.0 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 ThiF family FA_hydroxylase PF04116.13 EMR62826.1 - 6.9e-25 87.9 19.9 6.9e-25 87.9 19.9 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AAA PF00004.29 EMR62827.1 - 7.6e-52 175.2 0.0 1.1e-39 135.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMR62827.1 - 6.9e-09 35.4 0.0 1.6e-05 24.6 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EMR62827.1 - 1e-07 32.5 0.4 0.0017 18.7 0.0 3.7 3 2 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 EMR62827.1 - 3e-06 27.5 0.0 0.0017 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EMR62827.1 - 3.1e-06 27.3 0.0 0.004 17.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EMR62827.1 - 7.2e-06 26.3 0.1 0.022 15.1 0.0 3.4 3 2 1 4 4 3 2 AAA domain AAA_5 PF07728.14 EMR62827.1 - 4.1e-05 23.6 0.1 0.014 15.4 0.0 3.5 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EMR62827.1 - 0.00013 22.3 0.1 0.13 12.4 0.0 3.5 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 EMR62827.1 - 0.00015 22.1 0.0 0.82 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 EMR62827.1 - 0.00035 20.5 0.3 0.27 11.1 0.0 3.2 2 1 1 3 3 3 1 NACHT domain AAA_2 PF07724.14 EMR62827.1 - 0.00038 20.6 0.0 0.004 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EMR62827.1 - 0.0014 18.3 0.5 3.8 7.0 0.0 4.0 2 2 2 4 4 4 1 AAA domain Mg_chelatase PF01078.21 EMR62827.1 - 0.0031 16.9 0.2 0.38 10.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CDC48_N PF02359.18 EMR62827.1 - 0.0057 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EMR62827.1 - 0.013 15.3 0.0 0.091 12.5 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 EMR62827.1 - 0.02 14.2 0.1 4.5 6.5 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin TIP49 PF06068.13 EMR62827.1 - 0.024 13.9 0.0 0.099 11.8 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 EMR62827.1 - 0.044 13.5 0.0 21 4.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EMR62827.1 - 0.053 13.0 0.0 6.3 6.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 EMR62827.1 - 0.18 11.7 0.0 0.54 10.2 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain Vps4_C PF09336.10 EMR62827.1 - 0.24 11.4 0.5 23 5.0 0.0 3.3 4 0 0 4 4 3 0 Vps4 C terminal oligomerisation domain ATPase PF06745.13 EMR62827.1 - 0.31 10.3 0.9 80 2.5 0.0 3.1 2 1 1 3 3 3 0 KaiC Mito_carr PF00153.27 EMR62828.1 - 5.9e-45 151.1 1.6 1.6e-20 72.8 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Lipase_GDSL_2 PF13472.6 EMR62829.1 - 5.1e-17 62.8 0.2 7.6e-17 62.3 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR62829.1 - 1.5e-07 31.6 0.1 5.1e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MRP-L51 PF10244.9 EMR62829.1 - 0.057 13.6 0.1 0.3 11.3 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit Peptidase_S24 PF00717.23 EMR62830.1 - 3.5e-05 23.7 0.0 0.00011 22.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EMR62830.1 - 0.0047 16.7 0.0 0.079 12.7 0.0 2.1 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 SR-25 PF10500.9 EMR62831.1 - 0.27 10.8 28.5 0.24 11.0 9.0 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 EMR62831.1 - 0.73 10.5 14.3 3.7 8.2 3.6 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3391 PF11871.8 EMR62831.1 - 3.2 8.3 8.9 2.2 8.8 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) SUIM_assoc PF16619.5 EMR62831.1 - 4 7.6 16.9 47 4.2 0.2 3.8 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 FAM60A PF15396.6 EMR62831.1 - 9.4 6.2 8.0 8.4 6.3 0.2 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Roughex PF06020.11 EMR62831.1 - 9.5 5.2 8.6 19 4.2 8.6 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Pterin_4a PF01329.19 EMR62832.1 - 9.8e-06 25.7 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Flg_bb_rod PF00460.20 EMR62832.1 - 0.2 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Flagella basal body rod protein DnaJ PF00226.31 EMR62834.1 - 1.5e-10 41.0 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Peptidase_M43 PF05572.13 EMR62835.1 - 8.4e-14 51.7 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EMR62835.1 - 0.0015 18.7 0.2 0.0025 18.0 0.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 EMR62835.1 - 0.0018 18.1 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 EMR62835.1 - 0.018 14.7 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EMR62835.1 - 0.023 13.9 0.1 0.049 12.8 0.0 1.6 2 0 0 2 2 2 0 Met-zincin Reprolysin_2 PF13574.6 EMR62835.1 - 0.077 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like USP19_linker PF16602.5 EMR62835.1 - 0.084 13.4 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase Peptidase_M66 PF10462.9 EMR62835.1 - 0.1 11.5 0.5 0.17 10.8 0.5 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 EMR62835.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 EMR62835.1 - 0.13 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family LNS2 PF08235.13 EMR62836.1 - 1.4e-91 306.0 0.0 2e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EMR62836.1 - 8.4e-42 141.3 0.0 2.6e-41 139.7 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EMR62836.1 - 0.00044 19.9 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.21 EMR62837.1 - 2.3e-09 37.5 0.0 5.7e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF3584 PF12128.8 EMR62837.1 - 0.55 7.7 33.6 0.91 7.0 33.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Amidohydro_1 PF01979.20 EMR62838.1 - 1.1e-39 136.8 0.1 1.2e-39 136.6 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR62838.1 - 1.3e-07 31.5 2.3 1.4e-06 28.1 0.4 2.2 2 0 0 2 2 2 2 Amidohydrolase family Met_10 PF02475.16 EMR62839.1 - 0.00037 20.3 0.0 0.0032 17.3 0.0 2.1 1 1 1 2 2 2 1 Met-10+ like-protein SSXT PF05030.12 EMR62839.1 - 0.0024 17.5 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) MtmB PF05369.12 EMR62839.1 - 0.041 12.7 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Pkinase_Tyr PF07714.17 EMR62840.1 - 0.072 12.4 0.0 3.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase CAP59_mtransfer PF11735.8 EMR62842.1 - 8.6e-80 267.9 0.0 1.1e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 zf-C2H2 PF00096.26 EMR62843.1 - 2.3e-14 52.9 12.5 1.5e-06 28.3 2.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMR62843.1 - 9.6e-14 51.1 8.5 7.7e-08 32.4 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMR62843.1 - 7.5e-10 38.8 11.5 0.00017 22.2 1.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMR62843.1 - 2.9e-09 36.7 5.4 0.00013 21.8 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMR62843.1 - 1.4e-07 31.6 0.3 0.037 14.3 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMR62843.1 - 6.6e-06 26.3 1.7 0.0056 17.0 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EMR62843.1 - 0.00078 19.1 5.4 0.17 11.6 0.7 3.3 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-Di19 PF05605.12 EMR62843.1 - 0.027 14.8 1.4 0.051 13.9 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 EMR62843.1 - 0.08 13.2 3.8 7.1 6.9 0.1 2.6 1 1 1 2 2 2 0 LIM domain Zn_ribbon_recom PF13408.6 EMR62843.1 - 0.085 13.4 0.8 0.085 13.4 0.8 1.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 EMR62843.1 - 0.16 12.5 4.0 3.2 8.3 0.4 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C5HCH PF17982.1 EMR62843.1 - 0.81 9.9 6.8 7.6 6.8 1.1 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-BED PF02892.15 EMR62843.1 - 1 9.5 3.0 14 5.7 0.5 2.5 1 1 1 2 2 2 0 BED zinc finger FYVE PF01363.21 EMR62843.1 - 1 9.5 5.6 2.6 8.3 5.8 1.6 1 1 0 1 1 1 0 FYVE zinc finger LSM PF01423.22 EMR62844.1 - 2.2e-20 72.1 0.1 2.5e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMR62844.1 - 0.00033 20.7 0.1 0.00038 20.5 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EMR62844.1 - 0.0027 17.8 0.1 0.0031 17.6 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 EMR62844.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Rad60-SLD PF11976.8 EMR62846.1 - 2.5e-17 62.4 0.2 7.2e-17 61.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EMR62846.1 - 0.00028 20.6 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family TmoB PF06234.12 EMR62846.1 - 0.0061 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Toluene-4-monooxygenase system protein B (TmoB) PNISR PF15996.5 EMR62846.1 - 3.1 8.0 18.8 9.1 6.5 12.3 3.3 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR DUF4246 PF14033.6 EMR62847.1 - 7.6e-145 483.5 0.0 8.9e-106 354.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) AroM PF07302.11 EMR62847.1 - 0.12 11.7 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 AroM protein MDM31_MDM32 PF08118.11 EMR62848.1 - 1.5e-249 829.0 0.0 1.8e-249 828.8 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins adh_short PF00106.25 EMR62850.1 - 0.00022 20.7 0.1 0.00027 20.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR62850.1 - 0.0015 18.5 0.2 0.0019 18.1 0.2 1.0 1 0 0 1 1 1 1 KR domain eIF3_subunit PF08597.10 EMR62851.1 - 2e-75 253.8 24.3 2.5e-75 253.5 24.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PRP4 PF08799.11 EMR62851.1 - 0.07 12.7 1.4 0.94 9.1 3.5 1.7 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like YL1 PF05764.13 EMR62851.1 - 0.93 9.6 25.9 0.12 12.5 17.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Rrn6 PF10214.9 EMR62851.1 - 2.2 6.7 8.2 3.1 6.2 8.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC27 PF09507.10 EMR62851.1 - 3.1 7.1 23.3 0.38 10.1 15.5 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Nop53 PF07767.11 EMR62851.1 - 3.5 6.9 27.2 1.8 7.9 20.1 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDPS PF16715.5 EMR62851.1 - 4.9 6.7 9.7 19 4.8 5.4 2.1 2 0 0 2 2 2 0 Cyclodipeptide synthase KH_8 PF17903.1 EMR62852.1 - 1.4e-05 25.0 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EMR62852.1 - 0.018 14.8 0.6 0.058 13.2 0.6 1.8 2 0 0 2 2 2 0 KH domain Methyltransf_11 PF08241.12 EMR62853.1 - 6.3e-13 49.2 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR62853.1 - 4.2e-11 43.4 0.0 7.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR62853.1 - 4.5e-05 22.9 0.0 6.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMR62853.1 - 5.8e-05 23.8 0.0 0.00015 22.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR62853.1 - 0.037 13.8 0.0 0.29 10.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMR62853.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EMR62853.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) FtsJ PF01728.19 EMR62853.1 - 0.17 12.0 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Tim17 PF02466.19 EMR62854.1 - 2.5e-16 60.0 1.1 4.1e-16 59.3 1.1 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 EMR62854.1 - 0.0019 18.3 1.4 0.69 10.1 0.3 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5518) DiSB-ORF2_chro PF16506.5 EMR62855.1 - 0.034 14.1 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative virion glycoprotein of insect viruses Kdo PF06293.14 EMR62855.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AOX PF01786.17 EMR62856.1 - 1.2e-67 227.6 0.0 2.5e-38 131.8 0.0 2.0 1 1 1 2 2 2 2 Alternative oxidase LSM PF01423.22 EMR62858.1 - 1e-18 66.7 0.2 1.3e-18 66.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EMR62858.1 - 0.01 15.4 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 EMR62858.1 - 0.039 14.1 0.0 0.05 13.7 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 EMR62858.1 - 0.069 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Epimerase PF01370.21 EMR62860.1 - 1.5e-05 24.6 0.0 0.00034 20.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR62860.1 - 0.00074 19.5 0.0 0.0018 18.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EMR62860.1 - 0.0067 15.5 0.0 0.0091 15.0 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMR62860.1 - 0.064 12.4 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 EMR62860.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase SAP130_C PF16014.5 EMR62860.1 - 0.081 12.0 1.6 0.099 11.7 1.6 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus NmrA PF05368.13 EMR62860.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family MS_channel PF00924.18 EMR62861.1 - 5.7e-17 62.0 4.1 1e-16 61.1 4.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 EMR62861.1 - 0.0025 17.2 0.1 0.0069 15.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EMR62861.1 - 0.005 16.3 0.2 0.013 15.0 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EMR62861.1 - 0.018 15.5 0.1 0.048 14.1 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EMR62861.1 - 0.076 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 EMR62861.1 - 0.1 12.5 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 EF-hand domain pair Reticulon PF02453.17 EMR62861.1 - 3.6 7.5 12.7 0.3 11.1 3.8 2.7 2 0 0 2 2 2 0 Reticulon Spore_YabQ PF09578.10 EMR62861.1 - 4.3 7.6 13.5 1.9 8.7 2.8 2.6 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) His_Phos_1 PF00300.22 EMR62863.1 - 1.4e-10 41.2 0.0 2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CotJB PF12652.7 EMR62864.1 - 0.099 12.9 0.0 1.5 9.1 0.0 2.6 2 1 0 2 2 2 0 CotJB protein PTS_IIA PF02255.16 EMR62864.1 - 0.44 10.6 3.7 0.59 10.2 2.0 2.0 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Aldo_ket_red PF00248.21 EMR62865.1 - 1.4e-55 188.6 0.0 1.6e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Thi4 PF01946.17 EMR62865.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AF-4 PF05110.13 EMR62866.1 - 0.045 11.9 4.6 0.065 11.3 4.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GMC_oxred_N PF00732.19 EMR62867.1 - 4e-49 167.6 0.0 4.8e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMR62867.1 - 3.8e-06 26.2 0.1 5.5e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR62867.1 - 1.7e-05 24.1 0.0 0.0086 15.2 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 EMR62867.1 - 2.8e-05 23.4 1.2 0.15 11.1 0.5 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 EMR62867.1 - 4.9e-05 23.1 1.1 0.0014 18.3 1.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR62867.1 - 0.0001 21.7 0.2 0.00081 18.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR62867.1 - 0.00032 20.1 0.1 0.074 12.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR62867.1 - 0.0045 17.2 0.5 0.012 15.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMR62867.1 - 0.012 14.3 0.1 0.1 11.3 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 EMR62867.1 - 0.019 14.9 0.2 0.037 14.0 0.2 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMR62867.1 - 0.058 14.0 0.5 0.11 13.0 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR62867.1 - 0.11 11.3 0.5 0.16 10.8 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 EMR62867.1 - 0.37 10.1 2.7 0.74 9.1 2.5 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Methyltransf_24 PF13578.6 EMR62868.1 - 0.018 16.1 0.0 0.061 14.4 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain SSP160 PF06933.11 EMR62868.1 - 0.06 11.6 1.3 0.079 11.1 1.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltransf_25 PF13649.6 EMR62868.1 - 0.079 13.7 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 EMR62869.1 - 2e-50 171.6 0.0 2.3e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR62869.1 - 9.3e-44 149.2 0.2 1.2e-43 148.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR62869.1 - 3.9e-11 43.2 0.1 5.4e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 EMR62869.1 - 0.011 15.7 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus T2SSE PF00437.20 EMR62870.1 - 0.075 12.1 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein GMC_oxred_N PF00732.19 EMR62873.1 - 7.6e-59 199.5 0.0 1.5e-58 198.6 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR62873.1 - 5.5e-34 117.8 0.2 1.1e-33 116.8 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMR62873.1 - 1.5e-05 24.2 0.1 2.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR62873.1 - 7.9e-05 21.9 0.1 0.0032 16.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EMR62873.1 - 0.00016 21.9 0.1 0.00042 20.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR62873.1 - 0.00061 19.5 0.6 0.0055 16.3 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR62873.1 - 0.00073 18.9 0.0 0.0015 17.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR62873.1 - 0.0078 15.5 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR62873.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EMR62873.1 - 0.019 13.7 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 EMR62873.1 - 0.045 14.0 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 EMR62873.1 - 0.05 14.2 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR62873.1 - 0.059 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EMR62873.1 - 0.13 11.1 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EMR62873.1 - 0.18 11.8 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Tyr-DNA_phospho PF06087.12 EMR62874.1 - 3.6e-33 115.1 0.0 4.5e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EMR62874.1 - 0.0093 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain Glyco_hydro_127 PF07944.12 EMR62876.1 - 4.8e-17 61.7 0.0 8.7e-17 60.8 0.0 1.3 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_3_C PF01915.22 EMR62877.1 - 1.4e-49 168.8 0.0 1.8e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EMR62877.1 - 6.3e-15 55.0 0.2 1.6e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EMR62877.1 - 1.6e-10 41.0 0.2 4.5e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 PA14 domain DUF11 PF01345.18 EMR62877.1 - 0.01 16.1 0.7 0.04 14.2 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF11 Wzt_C PF14524.6 EMR62877.1 - 0.012 15.7 0.1 3 7.9 0.0 2.7 2 1 0 2 2 2 0 Wzt C-terminal domain DUF1616 PF07760.11 EMR62877.1 - 0.042 13.2 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) CARDB PF07705.11 EMR62877.1 - 0.095 13.0 0.5 1 9.6 0.3 2.6 2 1 1 3 3 3 0 CARDB fn3_6 PF17766.1 EMR62877.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type-III domain Astro_capsid_p PF12226.8 EMR62878.1 - 0.045 12.9 1.3 0.042 13.0 1.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-C2H2 PF00096.26 EMR62880.1 - 8.4e-06 26.0 10.7 0.1 13.1 0.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR62880.1 - 2.7e-05 24.6 11.5 0.2 12.6 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMR62880.1 - 0.078 13.4 0.7 0.078 13.4 0.7 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 EMR62880.1 - 8.2 6.3 7.5 41 4.1 0.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Cation_efflux PF01545.21 EMR62881.1 - 5.3e-50 169.9 6.1 6.7e-50 169.6 6.1 1.1 1 0 0 1 1 1 1 Cation efflux family ORF_2_N PF18492.1 EMR62881.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Open reading frame 2 N-terminal domain SPX PF03105.19 EMR62881.1 - 3.9 7.3 6.8 14 5.5 0.3 2.1 2 0 0 2 2 2 0 SPX domain Clp1 PF06807.14 EMR62882.1 - 7.2e-33 113.5 0.1 2.2e-32 111.9 0.0 1.9 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_P PF16575.5 EMR62882.1 - 1.4e-31 109.8 0.0 1.5e-30 106.4 0.0 2.3 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EMR62882.1 - 3.6e-25 88.0 0.0 1.4e-24 86.2 0.0 2.0 1 1 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor MMR_HSR1 PF01926.23 EMR62882.1 - 6.2e-06 26.3 0.3 4.4e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EMR62882.1 - 0.00012 21.9 0.0 0.00048 20.0 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EMR62882.1 - 0.0058 16.9 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMR62882.1 - 0.0091 16.2 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMR62882.1 - 0.034 14.7 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EMR62882.1 - 0.083 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EMR62882.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain PPC PF04151.15 EMR62882.1 - 0.15 13.1 0.4 0.15 13.1 0.4 2.9 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain RsgA_GTPase PF03193.16 EMR62882.1 - 0.22 11.4 0.2 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Arb1 PF09692.10 EMR62883.1 - 2.1e-130 435.5 0.0 2.6e-130 435.2 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 7TMR-HDED PF07697.11 EMR62883.1 - 0.0014 18.8 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 7TM-HD extracellular IPK PF03770.16 EMR62884.1 - 1.1e-47 162.5 0.0 1.5e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase NdhM PF10664.9 EMR62884.1 - 0.03 14.6 0.6 0.19 12.0 0.3 2.3 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M V_ATPase_I_N PF18670.1 EMR62884.1 - 0.044 14.2 0.6 4.9 7.6 0.0 2.6 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain CAP_N PF01213.19 EMR62885.1 - 0.19 11.2 0.4 0.31 10.5 0.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Androgen_recep PF02166.16 EMR62885.1 - 0.25 10.1 1.1 0.38 9.5 1.1 1.2 1 0 0 1 1 1 0 Androgen receptor IML1 PF12257.8 EMR62886.1 - 1.9e-100 335.7 0.3 2.9e-100 335.1 0.3 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EMR62886.1 - 1.9e-27 95.1 0.1 4.5e-27 93.9 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) adh_short PF00106.25 EMR62887.1 - 3.8e-30 104.8 0.3 7.7e-26 90.8 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62887.1 - 8.7e-21 74.5 0.4 1.5e-18 67.2 0.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62887.1 - 1.8e-08 34.5 0.1 3.2e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR62887.1 - 0.00011 21.8 0.2 0.00027 20.5 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMR62887.1 - 0.0076 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMR62887.1 - 0.017 14.5 0.2 0.074 12.4 0.2 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase FGGY_N PF00370.21 EMR62887.1 - 0.061 12.9 0.2 0.091 12.3 0.2 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain ZapD PF07072.11 EMR62887.1 - 0.18 11.6 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Cell division protein adh_short_C2 PF13561.6 EMR62888.1 - 2.8e-45 154.7 0.0 8.6e-24 84.4 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR62888.1 - 6.1e-35 120.5 0.2 5.8e-25 87.9 0.1 2.0 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR62888.1 - 5.9e-10 39.3 0.1 8.3e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR62888.1 - 0.0028 17.2 0.0 0.025 14.1 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 EMR62888.1 - 0.035 14.0 0.4 0.076 12.9 0.4 1.7 1 1 0 1 1 1 0 YjeF-related protein N-terminus NmrA PF05368.13 EMR62888.1 - 0.036 13.6 0.4 0.11 12.1 0.4 1.9 1 1 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EMR62888.1 - 0.075 12.4 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 EMR62888.1 - 0.41 10.4 4.4 7.1 6.4 4.4 2.2 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Na_Ca_ex PF01699.24 EMR62889.1 - 1e-38 132.6 33.2 5.5e-20 71.9 15.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Tad PF13400.6 EMR62889.1 - 0.15 12.4 10.3 6.8 7.1 0.2 4.4 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Cytochrom_C_asm PF01578.20 EMR62889.1 - 0.48 10.2 5.0 0.26 11.0 1.3 2.4 2 1 0 2 2 2 0 Cytochrome C assembly protein DUF1996 PF09362.10 EMR62890.1 - 2.2e-71 240.6 0.0 2.4e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SBP PF03110.14 EMR62891.1 - 0.014 15.7 2.2 0.024 14.9 2.2 1.4 1 0 0 1 1 1 0 SBP domain zf_C2H2_13 PF18508.1 EMR62891.1 - 9.8 5.9 7.3 2.5 7.8 0.3 2.8 3 0 0 3 3 3 0 Zinc finger domain CAP PF00188.26 EMR62892.1 - 1e-18 68.4 4.3 1.4e-18 67.9 4.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4106 PF13388.6 EMR62892.1 - 4.9 6.3 15.8 6.6 5.8 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) ADH_zinc_N PF00107.26 EMR62893.1 - 6.1e-10 39.2 0.0 1.8e-09 37.7 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR62893.1 - 4.5e-05 23.3 0.0 8.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMR62893.1 - 0.0016 19.5 0.1 0.0053 17.8 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NmrA PF05368.13 EMR62893.1 - 0.0045 16.6 2.2 0.013 15.0 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EMR62893.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.1 3 0 0 3 3 3 0 short chain dehydrogenase NAD_binding_10 PF13460.6 EMR62893.1 - 0.25 11.2 0.1 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_10 PF13460.6 EMR62894.1 - 7.3e-07 29.3 0.0 8.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR62894.1 - 6.7e-06 25.7 0.0 1.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR62894.1 - 0.00092 18.3 0.0 0.0024 16.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMR62894.1 - 0.0026 17.0 0.0 0.17 11.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein DapB_N PF01113.20 EMR62894.1 - 0.0049 17.0 0.1 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EMR62894.1 - 0.025 14.2 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EMR62894.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EMR62894.1 - 0.11 12.9 0.0 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PNGaseA PF12222.8 EMR62895.1 - 7.5e-161 535.8 1.5 1e-160 535.3 1.5 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Het-C PF07217.11 EMR62897.1 - 1.2e-41 143.0 0.3 1.5e-41 142.6 0.3 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Uso1_p115_C PF04871.13 EMR62897.1 - 0.045 14.1 1.8 0.1 12.9 1.8 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region P63C PF10546.9 EMR62897.1 - 0.073 13.7 0.1 0.31 11.7 0.0 2.1 2 0 0 2 2 2 0 P63C domain Peptidase_M28 PF04389.17 EMR62898.1 - 2.8e-29 102.2 0.0 5.4e-29 101.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M28 SinI PF08671.10 EMR62899.1 - 0.089 12.6 1.9 0.66 9.8 1.8 2.4 2 0 0 2 2 2 0 Anti-repressor SinI DUF1656 PF07869.12 EMR62899.1 - 0.67 10.0 6.2 0.3 11.1 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) CDP-OH_P_transf PF01066.21 EMR62900.1 - 5.1e-16 59.2 0.5 5.1e-16 59.2 0.5 2.8 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase TMEM208_SND2 PF05620.11 EMR62900.1 - 2 8.2 4.6 0.8 9.5 0.2 2.5 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Ribophorin_II PF05817.14 EMR62902.1 - 1.5e-28 99.8 0.1 5.2e-28 98.0 0.1 1.7 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II OSTbeta PF15048.6 EMR62902.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Glyco_transf_15 PF01793.16 EMR62904.1 - 1.4e-94 317.0 6.7 1.3e-61 208.7 0.8 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase EcKinase PF02958.20 EMR62905.1 - 7.4e-14 51.8 0.0 9.1e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 EMR62905.1 - 3.8e-09 35.9 0.0 5.4e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 EMR62905.1 - 2.8e-07 30.7 0.8 4.6e-07 30.0 0.8 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.29 EMR62906.1 - 2.1e-05 25.0 0.0 5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pribosyltran_N PF13793.6 EMR62907.1 - 1.1e-41 141.4 0.0 2.4e-41 140.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EMR62907.1 - 6.1e-34 117.6 0.0 1.9e-28 99.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EMR62907.1 - 2e-07 30.7 0.0 0.00096 18.7 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Fungal_trans PF04082.18 EMR62908.1 - 1.4e-25 89.9 0.0 2.4e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Haem_oxygenas_2 PF14518.6 EMR62908.1 - 0.13 12.1 0.2 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Iron-containing redox enzyme adh_short PF00106.25 EMR62910.1 - 3.5e-42 144.1 0.0 4e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62910.1 - 3.9e-27 95.3 0.0 4.6e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62910.1 - 2e-11 44.1 0.0 2.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 KR domain PRK PF00485.18 EMR62911.1 - 0.00016 21.5 0.0 0.00038 20.2 0.0 1.6 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EMR62911.1 - 0.0002 20.6 0.0 0.00028 20.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 EMR62911.1 - 0.0011 19.5 0.0 0.0039 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMR62911.1 - 0.0016 18.6 0.2 0.0027 17.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 EMR62911.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin T2SSE PF00437.20 EMR62911.1 - 0.005 15.9 0.0 0.023 13.8 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.6 EMR62911.1 - 0.0071 16.8 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EMR62911.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMR62911.1 - 0.011 16.1 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR62911.1 - 0.018 15.4 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EMR62911.1 - 0.028 14.3 0.1 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 EMR62911.1 - 0.041 13.6 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EMR62911.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase Viral_helicase1 PF01443.18 EMR62911.1 - 0.068 12.9 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MobB PF03205.14 EMR62911.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EMR62911.1 - 0.088 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 EMR62911.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MeaB PF03308.16 EMR62911.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GvpD PF07088.11 EMR62911.1 - 0.15 10.7 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein TsaE PF02367.17 EMR62911.1 - 0.21 11.6 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PRELI PF04707.14 EMR62913.1 - 6.8e-43 146.2 0.2 8.1e-43 146.0 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family Peptidase_M24 PF00557.24 EMR62914.1 - 4.3e-37 127.8 0.1 5.4e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 REV PF00424.18 EMR62914.1 - 0.39 10.8 1.8 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) Methyltransf_11 PF08241.12 EMR62915.1 - 9e-06 26.3 0.1 5.2e-05 23.8 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR62915.1 - 0.00019 20.8 0.1 0.0033 16.8 0.0 2.3 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EMR62915.1 - 0.0055 17.4 0.1 0.1 13.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR62915.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMR62915.1 - 0.049 13.5 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Gln-synt_C PF00120.24 EMR62916.1 - 1e-65 222.0 0.0 1.4e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EMR62916.1 - 1.2e-13 51.5 0.0 3.8e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase 3Beta_HSD PF01073.19 EMR62917.1 - 7.6e-53 179.3 0.3 9.3e-53 179.0 0.3 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMR62917.1 - 1.1e-29 103.6 0.1 1.5e-29 103.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR62917.1 - 6.6e-21 75.1 0.5 1.2e-19 71.0 0.5 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMR62917.1 - 9.1e-13 48.0 0.4 1.7e-07 30.7 0.2 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EMR62917.1 - 2.2e-06 27.0 0.1 3.6e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EMR62917.1 - 2.4e-05 23.6 3.4 2.6e-05 23.5 1.3 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EMR62917.1 - 0.12 12.3 1.8 2.9 7.8 1.8 2.5 1 1 0 1 1 1 0 KR domain PikAIV_N PF18605.1 EMR62919.1 - 0.12 11.9 1.0 0.93 9.1 0.2 2.3 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain UL16 PF17622.2 EMR62920.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral unique long protein 16 Pkinase PF00069.25 EMR62921.1 - 1.1e-35 123.2 0.0 1.7e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR62921.1 - 9.1e-21 74.3 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMR62921.1 - 0.043 12.8 0.0 0.073 12.0 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain SH3_19 PF18597.1 EMR62921.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain Beta-lactamase PF00144.24 EMR62922.1 - 2e-32 112.7 1.5 4.2e-18 65.7 0.1 2.1 1 1 1 2 2 2 2 Beta-lactamase Beta-lactamase2 PF13354.6 EMR62922.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.5 2 0 0 2 2 2 0 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 EMR62922.1 - 0.064 12.0 0.1 0.095 11.4 0.1 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family p450 PF00067.22 EMR62923.1 - 2.7e-47 161.6 0.0 2.5e-46 158.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.21 EMR62924.1 - 4.4e-37 127.7 0.0 5.4e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.21 EMR62925.1 - 1.1e-07 30.8 0.0 1.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III GST_N PF02798.20 EMR62926.1 - 3.2e-12 46.6 0.0 6.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR62926.1 - 2e-09 37.5 0.0 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR62926.1 - 2.2e-09 37.4 0.0 3.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR62926.1 - 8.2e-09 35.4 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR62926.1 - 2.7e-08 34.0 0.0 5.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR62926.1 - 2.1e-07 31.2 0.0 4.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EMR62926.1 - 0.12 13.0 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.26 EMR62927.1 - 4.8e-29 101.0 0.6 1e-28 99.9 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR62927.1 - 3e-16 60.7 0.0 7.1e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 EMR62927.1 - 0.00048 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ADH_N PF08240.12 EMR62927.1 - 0.024 14.5 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 EMR62927.1 - 0.1 12.3 0.3 0.24 11.1 0.2 1.4 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Myb_DNA-bind_4 PF13837.6 EMR62928.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Folliculin PF11704.8 EMR62928.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PDZ_1 PF12812.7 EMR62929.1 - 9.7e-51 169.7 0.1 4.9e-32 109.8 0.1 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EMR62929.1 - 1.1e-25 91.3 0.9 2.9e-21 76.9 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 EMR62929.1 - 5.8e-14 52.2 0.3 3.6e-06 27.2 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 EMR62929.1 - 1.8e-13 50.1 0.6 1.7e-05 24.6 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 EMR62929.1 - 4e-12 46.3 0.0 7.6e-06 26.2 0.0 4.0 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 EMR62929.1 - 0.00018 21.4 1.8 0.098 12.6 0.1 3.8 4 0 0 4 4 4 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 EMR62929.1 - 0.03 14.0 0.0 0.24 11.1 0.1 2.4 2 0 0 2 2 2 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal PDZ_3 PF17815.1 EMR62929.1 - 0.12 12.3 0.0 26 4.7 0.0 3.2 3 0 0 3 3 3 0 PDZ domain Peptidase_S46 PF10459.9 EMR62929.1 - 0.19 10.3 0.1 0.32 9.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase S46 Plasmodium_Vir PF05795.11 EMR62930.1 - 0.86 9.0 10.8 1.2 8.5 10.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GREB1 PF15782.5 EMR62930.1 - 1.6 5.7 10.6 1.8 5.6 10.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 EMR62930.1 - 3.5 6.1 11.3 4.2 5.8 11.3 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 EMR62930.1 - 5.8 6.7 15.6 7.4 6.4 15.6 1.1 1 0 0 1 1 1 0 SPX domain CytochromB561_N PF09786.9 EMR62930.1 - 8.1 5.3 23.9 10 5.0 23.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal HsbA PF12296.8 EMR62932.1 - 8.3e-07 29.5 0.1 1.6e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FAM75 PF14650.6 EMR62932.1 - 6.2 6.3 10.4 9.3 5.7 10.4 1.2 1 0 0 1 1 1 0 FAM75 family DUF3176 PF11374.8 EMR62933.1 - 4.5e-24 84.7 0.5 1.1e-23 83.4 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) TerC PF03741.16 EMR62933.1 - 0.067 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Integral membrane protein TerC family DUF4588 PF15251.6 EMR62934.1 - 6.8e-08 32.6 4.7 1.5e-07 31.5 4.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) MFS_1 PF07690.16 EMR62935.1 - 2.4e-31 109.0 47.2 3.4e-20 72.3 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR62935.1 - 2.6e-05 23.0 21.2 0.00018 20.2 20.4 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein SNF2_N PF00176.23 EMR62936.1 - 5.6e-76 255.5 0.3 1.2e-75 254.5 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EMR62936.1 - 1e-43 147.9 3.6 1e-43 147.9 3.6 2.4 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EMR62936.1 - 1.4e-35 122.4 4.1 1.4e-35 122.4 4.1 3.8 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 EMR62936.1 - 9.8e-19 67.7 0.2 5.1e-18 65.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR62936.1 - 9.7e-11 42.0 0.6 4.7e-10 39.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 EMR62936.1 - 4.1e-07 30.1 0.0 0.001 19.2 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 EMR62936.1 - 9e-06 25.1 0.0 5.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EMR62936.1 - 0.00061 19.5 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 EMR62936.1 - 0.00062 19.6 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 EMR62936.1 - 0.056 13.5 0.2 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.15 EMR62936.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 p450 PF00067.22 EMR62937.1 - 1e-37 130.0 0.0 2.3e-35 122.2 0.0 2.9 1 1 1 2 2 2 2 Cytochrome P450 Rho_N PF07498.12 EMR62938.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain WD40 PF00400.32 EMR62939.1 - 5.4e-27 93.5 2.1 5.8e-09 36.4 0.1 6.1 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR62939.1 - 1.2e-14 54.4 0.0 0.00067 19.9 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMR62939.1 - 0.0065 16.4 0.2 0.29 11.0 0.1 2.8 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 EMR62939.1 - 0.014 15.2 1.4 0.14 11.9 0.4 2.1 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 EMR62939.1 - 0.014 14.8 0.0 1.6 8.0 0.0 2.6 1 1 1 2 2 2 0 WD40-like domain Nup160 PF11715.8 EMR62939.1 - 0.018 13.7 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Prim-Pol PF09250.11 EMR62939.1 - 0.1 13.0 0.7 1.5 9.1 0.0 2.2 1 1 1 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal PALB2_WD40 PF16756.5 EMR62939.1 - 0.12 11.2 0.1 13 4.6 0.0 2.3 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Peptidase_S9 PF00326.21 EMR62940.1 - 1.2e-35 123.0 0.0 1.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EMR62940.1 - 0.00062 19.6 0.7 0.37 10.8 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EMR62940.1 - 0.0016 17.3 0.1 0.017 13.9 0.0 2.3 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Arylesterase PF01731.20 EMR62940.1 - 0.13 12.5 0.1 3.9 7.8 0.0 3.2 3 0 0 3 3 3 0 Arylesterase F-box-like PF12937.7 EMR62941.1 - 4.1e-07 29.8 0.1 1.1e-06 28.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR62941.1 - 0.0075 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain MFS_MOT1 PF16983.5 EMR62942.1 - 8.7e-61 203.2 37.7 1.4e-33 115.6 11.3 2.8 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Trp_oprn_chp PF09534.10 EMR62942.1 - 0.079 12.8 17.9 0.1 12.4 3.3 3.5 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Forkhead PF00250.18 EMR62943.1 - 2.9e-16 59.5 0.0 6.2e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EMR62943.1 - 1.6e-05 25.2 0.0 3.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Closter_coat PF01785.17 EMR62944.1 - 0.085 12.1 0.5 0.28 10.4 0.1 1.9 2 0 0 2 2 2 0 Closterovirus coat protein I-set PF07679.16 EMR62945.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain FTHFS PF01268.19 EMR62946.1 - 5e-254 843.6 0.0 6.9e-254 843.2 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EMR62946.1 - 7.4e-69 230.1 3.4 7.5e-69 230.1 0.6 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EMR62946.1 - 9.8e-38 129.0 0.7 2.1e-37 127.9 0.7 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EMR62946.1 - 0.0055 15.7 0.1 0.01 14.8 0.1 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family AlaDh_PNT_C PF01262.21 EMR62946.1 - 0.02 14.2 0.1 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2618 PF10940.8 EMR62947.1 - 0.57 10.0 0.1 0.57 10.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2618) EamA PF00892.20 EMR62948.1 - 3.6e-25 88.7 34.3 4.5e-13 49.5 14.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 EMR62948.1 - 0.46 8.7 12.3 0.068 11.5 0.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Trp_oprn_chp PF09534.10 EMR62948.1 - 2.7 7.8 9.4 19 5.0 6.4 2.9 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) WD40 PF00400.32 EMR62949.1 - 8.4e-38 127.7 19.4 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR62949.1 - 6.5e-14 52.0 0.1 0.00039 20.7 0.1 4.6 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR62949.1 - 3.4e-05 23.0 0.1 0.86 8.5 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EMR62949.1 - 0.00013 21.9 0.0 0.11 12.4 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EMR62949.1 - 0.0029 17.0 0.0 0.26 10.6 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain Lipoprotein_6 PF01441.19 EMR62949.1 - 0.14 12.2 0.7 0.23 11.5 0.7 1.2 1 0 0 1 1 1 0 Lipoprotein AMP-binding PF00501.28 EMR62950.1 - 3.9e-44 150.9 0.0 4.7e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR62950.1 - 8.8e-06 26.6 0.6 3.1e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EMR62950.1 - 0.0045 16.9 2.5 0.2 11.6 0.3 3.3 2 1 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus zf-RanBP PF00641.18 EMR62951.1 - 0.16 11.3 1.8 0.29 10.5 1.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Amidase PF01425.21 EMR62952.1 - 6.9e-92 308.8 0.1 8.8e-92 308.4 0.1 1.1 1 0 0 1 1 1 1 Amidase Aminotran_1_2 PF00155.21 EMR62954.1 - 8.5e-59 199.5 0.0 1.2e-58 199.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMR62954.1 - 0.03 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase FAD_binding_4 PF01565.23 EMR62955.1 - 2.3e-24 85.7 1.8 2.3e-24 85.7 1.8 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EMR62955.1 - 0.0005 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FA_desaturase_2 PF03405.14 EMR62955.1 - 0.084 11.7 0.5 0.5 9.1 0.0 2.1 2 0 0 2 2 2 0 Fatty acid desaturase CRCB PF02537.15 EMR62956.1 - 2.6e-11 43.7 0.0 3.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) YEATS PF03366.16 EMR62957.1 - 4.5e-21 74.6 0.1 1e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EMR62957.1 - 0.0016 18.5 0.1 0.0042 17.2 0.1 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation UPRTase PF14681.6 EMR62959.1 - 4.8e-75 251.5 0.0 5.5e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EMR62959.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 EMR62959.1 - 0.01 15.2 0.8 0.23 10.8 0.2 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase NmrA PF05368.13 EMR62960.1 - 8.6e-27 94.2 0.0 4.8e-24 85.2 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR62960.1 - 2.8e-13 50.1 0.7 7.2e-13 48.8 0.7 1.7 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EMR62960.1 - 0.00022 21.3 0.2 0.00034 20.7 0.2 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 EMR62960.1 - 0.0036 18.0 0.2 0.0065 17.2 0.2 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 EMR62960.1 - 0.0085 16.5 0.2 0.014 15.8 0.2 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EMR62960.1 - 0.021 15.4 0.2 0.048 14.2 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.15 EMR62961.1 - 3.8e-38 131.0 0.0 5.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EMR62961.1 - 1.3e-11 45.3 0.3 1.3e-11 45.3 0.3 2.8 3 0 0 3 3 3 1 FDF domain DUF5308 PF17233.2 EMR62961.1 - 2.5 8.3 6.7 17 5.6 3.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Glyco_hydro_18 PF00704.28 EMR62962.1 - 1.4e-75 254.9 0.9 1.6e-75 254.7 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 A_deaminase PF00962.22 EMR62963.1 - 6.5e-27 94.7 0.0 8.1e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pterin_bind PF00809.22 EMR62963.1 - 0.09 12.4 0.0 4.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Pterin binding enzyme Fungal_trans PF04082.18 EMR62964.1 - 1.2e-14 54.0 0.3 1.9e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HicB PF05534.12 EMR62964.1 - 0.096 12.5 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 HicB family p450 PF00067.22 EMR62965.1 - 1.5e-11 43.8 0.0 1.7e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alpha-amylase PF00128.24 EMR62966.1 - 1.2e-108 363.7 0.0 1.6e-108 363.2 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EMR62966.1 - 7.4e-05 22.8 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EMR62966.1 - 0.00049 19.3 0.0 0.00075 18.7 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DNA_ligase_A_M PF01068.21 EMR62967.1 - 9.3e-45 152.8 0.1 2e-44 151.7 0.0 1.6 2 0 0 2 2 2 1 ATP dependent DNA ligase domain BRCT_2 PF16589.5 EMR62967.1 - 8.1e-19 67.8 0.0 1.7e-10 41.2 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 EMR62967.1 - 1.2e-16 61.2 0.0 3.8e-16 59.5 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EMR62967.1 - 4e-15 56.5 0.0 8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 EMR62967.1 - 2e-07 31.3 0.0 0.00014 22.1 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EMR62967.1 - 0.00038 20.7 0.0 0.1 12.9 0.0 2.5 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 EMR62967.1 - 0.002 18.2 0.0 0.002 18.2 0.0 2.0 3 0 0 3 3 2 1 DNA ligase IV PTCB-BRCT PF12738.7 EMR62967.1 - 0.0096 15.9 0.3 2.1 8.3 0.0 2.9 3 0 0 3 3 3 1 twin BRCT domain mRNA_cap_enzyme PF01331.19 EMR62967.1 - 0.028 14.2 0.1 9.6 6.0 0.0 2.5 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain RTT107_BRCT_5 PF16770.5 EMR62967.1 - 0.051 13.5 0.1 16 5.4 0.1 2.6 2 1 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Inj_translocase PF16928.5 EMR62967.1 - 5.4 6.4 6.4 2.6 7.5 1.3 2.1 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome PIF1 PF05970.14 EMR62968.1 - 2.5e-52 178.2 0.7 2e-43 148.9 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EMR62968.1 - 2.3e-21 76.4 0.0 3.8e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR62968.1 - 1.3e-11 45.0 0.0 2.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMR62968.1 - 4.6e-06 26.3 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EMR62968.1 - 4.9e-06 26.9 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EMR62968.1 - 6.9e-05 21.0 0.1 0.00039 18.5 0.0 1.9 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 EMR62968.1 - 0.00011 21.7 0.1 0.00081 18.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein UvrD_C_2 PF13538.6 EMR62968.1 - 0.00026 20.7 0.0 0.00083 19.1 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 EMR62968.1 - 0.0003 21.2 0.0 0.00063 20.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EMR62968.1 - 0.00031 19.9 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 EMR62968.1 - 0.00047 20.6 0.0 0.00094 19.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EMR62968.1 - 0.003 18.1 0.1 0.01 16.3 0.0 1.9 1 1 1 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 EMR62968.1 - 0.0092 15.7 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EMR62968.1 - 0.011 15.6 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase TEX33 PF15400.6 EMR62968.1 - 0.012 16.1 0.2 0.028 14.9 0.2 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family NACHT PF05729.12 EMR62968.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 EMR62968.1 - 0.013 15.2 0.0 0.083 12.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 EMR62968.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 EMR62968.1 - 0.02 14.7 0.0 0.02 14.7 0.0 2.6 3 1 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EMR62968.1 - 0.02 15.1 0.0 0.13 12.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 EMR62968.1 - 0.02 14.9 0.0 0.077 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR62968.1 - 0.02 15.3 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 EMR62968.1 - 0.021 14.6 0.0 3.5 7.3 0.0 2.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EMR62968.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EMR62968.1 - 0.027 14.5 0.1 2.7 8.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EMR62968.1 - 0.029 14.3 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 EMR62968.1 - 0.037 14.0 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EMR62968.1 - 0.038 13.2 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 EMR62968.1 - 0.043 14.3 0.0 0.21 12.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EMR62968.1 - 0.053 13.4 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 EMR62968.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 EMR62968.1 - 0.074 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 EMR62968.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Membr_traf_MHD PF10540.9 EMR62968.1 - 0.094 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain DUF815 PF05673.13 EMR62968.1 - 0.11 11.7 0.0 0.24 10.5 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 EMR62968.1 - 0.12 11.5 0.0 2.6 7.2 0.0 2.6 3 0 0 3 3 3 0 TIP49 P-loop domain SAM_2 PF07647.17 EMR62969.1 - 6.5e-14 51.8 0.0 1.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EMR62969.1 - 1.7e-13 50.8 0.0 3.1e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EMR62969.1 - 8e-11 42.4 0.0 2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 EMR62969.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2239 PF09998.9 EMR62970.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF1993 PF09351.10 EMR62971.1 - 2.1e-47 161.2 0.0 2.4e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) RecC_C PF17946.1 EMR62971.1 - 0.14 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 RecC C-terminal domain FAD_binding_3 PF01494.19 EMR62972.1 - 4.4e-25 88.7 0.0 2.8e-24 86.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR62972.1 - 1.5e-06 27.7 0.0 0.0032 16.7 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR62972.1 - 1.6e-06 27.9 0.3 0.005 16.5 0.4 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR62972.1 - 3.6e-05 23.0 0.4 0.00021 20.5 0.1 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 EMR62972.1 - 5.7e-05 23.6 0.1 0.031 14.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR62972.1 - 0.00056 20.1 0.2 0.0016 18.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMR62972.1 - 0.004 15.9 0.1 2 7.0 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein SE PF08491.10 EMR62972.1 - 0.004 16.2 0.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.24 EMR62972.1 - 0.0064 15.6 0.1 0.0096 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR62972.1 - 0.01 15.1 0.2 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR62972.1 - 0.091 12.0 0.1 12 5.0 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GST_N PF02798.20 EMR62973.1 - 2.2e-06 27.9 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR62973.1 - 7e-05 23.0 0.0 0.00013 22.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR62973.1 - 0.0023 18.3 0.0 0.0039 17.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Podoplanin PF05808.11 EMR62974.1 - 0.86 9.7 19.1 1.3 9.1 19.1 1.3 1 0 0 1 1 1 0 Podoplanin GFA PF04828.14 EMR62975.1 - 8.9e-23 80.5 0.0 1.3e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DNA_ligase_ZBD PF03119.16 EMR62975.1 - 0.035 14.1 1.4 0.063 13.3 0.5 1.9 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 EMR62975.1 - 0.043 13.8 3.2 0.43 10.7 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 EMR62975.1 - 0.085 12.3 0.1 0.47 9.9 0.0 1.9 2 0 0 2 2 2 0 NMD3 family zf-ribbon_3 PF13248.6 EMR62975.1 - 0.13 11.7 0.2 0.13 11.7 0.2 2.6 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.6 EMR62975.1 - 0.17 11.9 0.3 9.3 6.3 0.0 2.2 1 1 1 2 2 2 0 CpXC protein zf_UBZ PF18439.1 EMR62975.1 - 0.19 11.4 2.4 0.8 9.4 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Nudix_N_2 PF14803.6 EMR62975.1 - 0.34 10.8 4.2 0.35 10.8 0.0 2.8 3 0 0 3 3 3 0 Nudix N-terminal zf-RING_7 PF02591.15 EMR62975.1 - 0.93 9.7 4.6 5.9 7.2 0.1 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain Arginase PF00491.21 EMR62976.1 - 1.9e-71 240.8 0.0 2.9e-35 122.1 0.0 2.0 2 0 0 2 2 2 2 Arginase family UPF0489 PF12640.7 EMR62976.1 - 0.047 13.9 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain SpoU_methylase PF00588.19 EMR62977.1 - 2.7e-27 95.7 0.0 3.7e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EMR62977.1 - 0.0057 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding ORC6 PF05460.13 EMR62979.1 - 0.64 9.2 3.5 1.4 8.1 3.5 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-PHD-like PF15446.6 EMR62981.1 - 1.6e-64 216.6 10.1 3.5e-64 215.5 10.1 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 EMR62981.1 - 7.4e-48 163.0 0.0 1.5e-47 162.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR62981.1 - 4.9e-20 71.9 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EMR62981.1 - 9.4e-09 34.8 0.8 3.5e-08 33.0 0.8 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EMR62981.1 - 2.6e-05 24.3 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMR62981.1 - 0.00071 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.29 EMR62981.1 - 0.0014 18.4 19.7 0.0021 17.9 3.3 4.1 3 1 0 4 4 4 2 PHD-finger Chromo PF00385.24 EMR62981.1 - 0.033 14.1 2.4 1.1 9.2 0.3 3.4 4 0 0 4 4 3 0 Chromo (CHRromatin Organisation MOdifier) domain PHD_4 PF16866.5 EMR62981.1 - 0.073 13.2 11.3 0.079 13.1 0.9 3.9 1 1 1 2 2 2 0 PHD-finger Zf_RING PF16744.5 EMR62981.1 - 0.077 13.1 7.2 3 8.0 1.8 3.0 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_2 PF13831.6 EMR62981.1 - 0.74 9.4 10.0 0.055 13.0 0.7 3.1 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 EMR62981.1 - 5.6 6.9 12.0 0.47 10.4 0.2 3.7 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CDH-cyt PF16010.5 EMR62982.1 - 1.9e-25 89.6 0.8 5.5e-25 88.1 0.5 1.9 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase HET PF06985.11 EMR62982.1 - 1.4e-12 48.2 5.3 2.8e-10 40.7 0.6 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Cytochrom_B561 PF03188.16 EMR62982.1 - 3.2e-11 43.5 9.6 3.2e-11 43.5 9.6 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EMR62982.1 - 2.1e-05 24.3 2.1 2.1e-05 24.3 2.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 EMR62982.1 - 0.01 16.0 4.8 0.033 14.4 4.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2231 PF09990.9 EMR62982.1 - 0.015 15.7 1.1 0.039 14.4 1.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) XK-related PF09815.9 EMR62982.1 - 0.15 11.1 3.2 0.18 10.8 0.6 2.4 2 1 0 2 2 2 0 XK-related protein Cation_efflux PF01545.21 EMR62982.1 - 0.21 11.3 4.0 0.38 10.4 4.0 1.4 1 0 0 1 1 1 0 Cation efflux family DUF2627 PF11118.8 EMR62982.1 - 0.32 11.6 6.5 0.25 11.9 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) Ferric_reduct PF01794.19 EMR62982.1 - 0.38 10.9 7.6 0.78 9.9 5.2 2.9 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF1129 PF06570.11 EMR62982.1 - 1.8 8.0 4.0 3.5 7.1 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) AAA PF00004.29 EMR62983.1 - 1.9e-18 67.2 0.0 3.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR62983.1 - 3.6e-05 24.2 0.0 0.00013 22.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EMR62983.1 - 0.00078 19.2 0.0 0.0032 17.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR62983.1 - 0.0044 17.3 0.0 0.022 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMR62983.1 - 0.014 15.9 0.0 0.072 13.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMR62983.1 - 0.017 15.1 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMR62983.1 - 0.019 15.1 0.0 0.68 10.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EMR62983.1 - 0.19 12.2 3.2 0.4 11.1 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.6 EMR62983.1 - 1 9.1 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain FMN_dh PF01070.18 EMR62984.1 - 6e-115 384.0 0.0 6.7e-115 383.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMR62984.1 - 2.1e-06 27.0 0.3 3.2e-06 26.4 0.3 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMR62984.1 - 0.0015 17.8 0.1 0.0023 17.2 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EMR62984.1 - 0.0033 16.9 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 EMR62984.1 - 0.063 12.5 0.2 0.16 11.2 0.1 1.6 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase ThiG PF05690.14 EMR62984.1 - 0.08 12.2 0.2 0.32 10.3 0.3 1.9 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 EMR62984.1 - 0.16 11.3 0.5 0.23 10.8 0.5 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase AA_permease PF00324.21 EMR62985.1 - 4.4e-110 368.5 40.2 5.1e-110 368.3 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR62985.1 - 3.9e-25 88.6 43.2 4.9e-25 88.2 43.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.8 EMR62985.1 - 0.044 13.9 1.6 9.6 6.3 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function Phage_holin_3_7 PF05449.11 EMR62985.1 - 5.2 7.2 9.2 0.48 10.5 0.8 3.0 2 0 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 Aldedh PF00171.22 EMR62986.1 - 4.6e-44 150.7 1.5 3.6e-18 65.3 0.0 4.0 1 1 3 4 4 4 4 Aldehyde dehydrogenase family PEPCK_ATP PF01293.20 EMR62987.1 - 1.6e-216 719.5 0.0 1.9e-216 719.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 EMR62987.1 - 0.054 13.9 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EMR62987.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 EMR62988.1 - 4.7e-12 47.0 3.0 2.6e-11 44.6 3.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR62988.1 - 0.001 18.7 0.0 0.017 14.8 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 EMR62988.1 - 0.21 11.4 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ribosomal_S17_N PF16205.5 EMR62989.1 - 2.2e-33 114.4 0.2 3.6e-33 113.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EMR62989.1 - 4.3e-26 90.8 0.2 9.2e-26 89.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 RGCC PF15151.6 EMR62990.1 - 0.0057 16.9 1.1 0.022 15.0 0.4 1.9 1 1 1 2 2 2 1 Response gene to complement 32 protein family L27_1 PF09058.10 EMR62990.1 - 0.076 13.0 3.9 0.58 10.2 1.4 2.2 2 0 0 2 2 2 0 L27_1 MAP7 PF05672.11 EMR62990.1 - 0.38 10.4 7.7 0.92 9.2 7.7 1.7 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family CEP63 PF17045.5 EMR62990.1 - 0.62 9.9 9.2 1.2 9.0 0.1 2.3 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa APG6 PF04111.12 EMR62991.1 - 3.9e-64 215.9 0.0 5.6e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EMR62991.1 - 2.7e-38 131.5 17.6 4e-38 130.9 17.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region YabA PF06156.13 EMR62991.1 - 0.29 11.8 3.9 0.52 11.0 3.4 1.6 1 1 0 1 1 1 0 Initiation control protein YabA FapA PF03961.13 EMR62991.1 - 0.32 9.5 2.0 0.46 9.0 2.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 EMR62991.1 - 0.38 10.8 9.5 0.85 9.7 9.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 EMR62991.1 - 0.41 9.1 5.9 0.63 8.5 5.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family MIS13 PF08202.11 EMR62991.1 - 0.6 9.3 10.3 0.73 9.1 9.8 1.3 1 1 0 1 1 1 0 Mis12-Mtw1 protein family HD_3 PF13023.6 EMR62991.1 - 0.8 9.6 6.8 1.4 8.8 6.8 1.3 1 0 0 1 1 1 0 HD domain zf-C4H2 PF10146.9 EMR62991.1 - 1.1 9.5 11.4 0.24 11.7 8.3 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein DUF3450 PF11932.8 EMR62991.1 - 1.2 8.4 12.9 4.9 6.4 11.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF2353 PF09789.9 EMR62991.1 - 1.3 8.3 11.4 2.6 7.3 11.4 1.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF4407 PF14362.6 EMR62991.1 - 1.6 8.0 6.7 2.5 7.4 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 EMR62991.1 - 2 8.7 9.4 9.7 6.5 9.3 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 EMR62991.1 - 2 8.2 10.7 0.5 10.2 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 EMR62991.1 - 2.4 5.9 4.7 3.3 5.5 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EMR62992.1 - 5.2e-41 140.8 0.0 6.6e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FAD_binding_4 PF01565.23 EMR62993.1 - 1.3e-11 44.4 0.0 3.2e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR62993.1 - 0.21 11.7 3.5 0.12 12.5 0.5 2.2 3 0 0 3 3 3 0 Berberine and berberine like DUF536 PF04394.14 EMR62994.1 - 0.028 14.3 0.1 0.028 14.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF536 CHCH PF06747.13 EMR62994.1 - 1.3 9.2 4.5 2 8.6 1.0 2.3 2 0 0 2 2 2 0 CHCH domain adh_short PF00106.25 EMR62995.1 - 1.3e-26 93.3 0.0 4.6e-24 85.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR62995.1 - 2.4e-13 50.2 0.0 3.9e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR62995.1 - 0.0093 15.9 0.1 0.058 13.3 0.0 2.1 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 EMR62995.1 - 0.05 13.3 0.2 0.31 10.7 0.2 2.1 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 EMR62995.1 - 0.051 13.0 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EMR62995.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 EMR62995.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.6 EMR62995.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Vps8 PF12816.7 EMR62996.1 - 2.5e-76 255.6 0.0 1.9e-75 252.7 0.0 2.4 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EMR62996.1 - 1.4e-07 31.5 0.3 0.0048 16.8 0.1 3.1 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 EMR62996.1 - 0.05 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger DUF692 PF05114.13 EMR62996.1 - 0.06 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF692) zf-RING_5 PF14634.6 EMR62996.1 - 0.075 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMR62996.1 - 0.086 12.9 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMR62996.1 - 0.23 11.4 0.4 0.75 9.7 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RNase_H PF00075.24 EMR62997.1 - 1.7e-17 64.0 0.0 3.5e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 RNase H Glyco_hydro2_C5 PF18565.1 EMR62998.1 - 8.6e-33 112.3 0.1 1.5e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 EMR62998.1 - 1.6e-25 89.8 0.0 3.1e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 EMR62998.1 - 3.9e-23 81.2 0.0 1.4e-22 79.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2 PF00703.21 EMR62998.1 - 9.9e-17 61.6 0.3 1.9e-16 60.7 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EMR62998.1 - 1.4e-14 54.3 0.0 4.1e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.6 EMR62998.1 - 0.00022 21.7 0.0 0.2 12.2 0.0 3.2 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 EMR62998.1 - 0.0055 17.0 2.8 0.01 16.1 0.1 2.5 3 0 0 3 3 3 1 Invasin, domain 3 COPR5 PF15340.6 EMR62998.1 - 0.0069 17.0 0.1 0.014 16.0 0.1 1.5 1 0 0 1 1 1 1 Cooperator of PRMT5 family DUF3752 PF12572.8 EMR62999.1 - 4.9e-46 157.0 6.3 4.9e-46 157.0 6.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) SurA_N_3 PF13624.6 EMR63000.1 - 0.1 12.4 0.6 0.15 11.9 0.6 1.3 1 0 0 1 1 1 0 SurA N-terminal domain zf-CCHC_5 PF14787.6 EMR63000.1 - 0.1 12.3 1.3 0.19 11.5 1.3 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Caps_synth PF05704.12 EMR63001.1 - 3.6e-08 33.1 0.0 7.2e-08 32.2 0.0 1.4 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein DUF3807 PF12720.7 EMR63002.1 - 2.1e-53 181.3 13.5 2.5e-53 181.0 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GAGA_bind PF06217.12 EMR63002.1 - 0.033 14.5 2.9 0.042 14.1 2.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SpoVR PF04293.13 EMR63002.1 - 1 8.0 3.9 1.4 7.5 3.9 1.1 1 0 0 1 1 1 0 SpoVR like protein DUF3381 PF11861.8 EMR63002.1 - 2.4 7.9 13.9 2.4 8.0 13.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) Pkinase PF00069.25 EMR63003.1 - 1e-65 221.8 0.0 1.2e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR63003.1 - 3.9e-18 65.7 0.0 5.6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMR63003.1 - 2.4e-08 34.2 0.0 5.2e-06 26.6 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMR63003.1 - 0.0067 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMR63003.1 - 0.0084 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMR63003.1 - 0.015 14.7 0.1 0.026 13.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EMR63003.1 - 0.019 14.5 1.0 0.079 12.5 0.1 2.4 3 0 0 3 3 3 0 Choline/ethanolamine kinase Oxidored_FMN PF00724.20 EMR63005.1 - 1.3e-62 212.0 0.0 1.6e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ACT PF01842.25 EMR63005.1 - 0.028 14.2 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 ACT domain Dus PF01207.17 EMR63005.1 - 0.086 11.9 0.0 0.43 9.6 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Spc7_N PF15402.6 EMR63007.1 - 3.8e-181 604.6 62.1 2.3e-106 357.2 46.7 2.6 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EMR63007.1 - 9.5e-126 418.9 8.6 9.5e-126 418.9 8.6 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EMR63007.1 - 3.1e-21 75.2 0.8 6.8e-21 74.1 0.8 1.6 1 0 0 1 1 1 1 Spc7_C2 TPR_MLP1_2 PF07926.12 EMR63007.1 - 0.0012 18.9 7.3 0.0012 18.9 7.3 3.0 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF4446 PF14584.6 EMR63007.1 - 0.12 12.4 1.6 1.4 8.8 1.6 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) ApoC-I PF04691.12 EMR63007.1 - 0.41 10.6 2.1 1.2 9.1 1.6 2.0 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) TMF_DNA_bd PF12329.8 EMR63007.1 - 0.46 10.5 15.9 0.057 13.4 2.9 3.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-H PF05837.12 EMR63007.1 - 0.82 10.1 14.1 0.02 15.3 2.9 3.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Pox_A_type_inc PF04508.12 EMR63007.1 - 1 9.3 5.6 1.1 9.3 0.1 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat kleA_kleC PF17383.2 EMR63007.1 - 1.1 9.6 5.8 1.3 9.4 3.4 2.4 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Seryl_tRNA_N PF02403.22 EMR63007.1 - 2.4 8.4 15.1 0.084 13.1 7.4 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 EMR63007.1 - 4 7.5 9.9 1.7 8.6 4.3 3.0 2 1 1 3 3 3 0 Laminin Domain II KASH_CCD PF14662.6 EMR63007.1 - 9.8 6.0 18.6 0.064 13.1 6.4 2.9 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ICL PF00463.21 EMR63009.1 - 9.6e-194 644.7 0.0 1.1e-193 644.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family adh_short_C2 PF13561.6 EMR63010.1 - 2.8e-54 184.1 0.6 3.2e-54 184.0 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR63010.1 - 1.3e-39 135.7 0.1 1.7e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR63010.1 - 4.7e-11 42.9 1.1 7e-11 42.4 1.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR63010.1 - 9.5e-05 21.7 0.1 0.00017 20.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EMR63010.1 - 0.00026 20.9 0.2 0.00061 19.7 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RecC_C PF17946.1 EMR63010.1 - 0.0075 16.1 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 RecC C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMR63010.1 - 0.0079 15.8 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 EMR63010.1 - 0.0098 16.6 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EMR63010.1 - 0.027 14.0 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ChuX_HutX PF06228.13 EMR63010.1 - 0.027 14.3 0.1 5.1 6.9 0.0 2.4 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX 3Beta_HSD PF01073.19 EMR63010.1 - 0.065 12.2 0.2 0.13 11.2 0.1 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_12 PF08242.12 EMR63010.1 - 0.12 13.2 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CRIM PF16978.5 EMR63011.1 - 5.3e-47 159.5 0.0 9.6e-47 158.7 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EMR63011.1 - 5.6e-29 100.6 0.0 1.3e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EMR63011.1 - 0.0063 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 EMR63011.1 - 0.16 12.0 0.1 0.43 10.7 0.1 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain DctQ PF04290.12 EMR63012.1 - 0.0052 16.7 4.7 0.01 15.7 4.7 1.4 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component Pkinase PF00069.25 EMR63013.1 - 1.3e-08 34.6 0.0 2e-05 24.1 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR63013.1 - 0.00024 20.5 0.0 0.18 11.1 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EMR63013.1 - 0.0042 17.0 3.7 0.011 15.7 0.1 2.7 2 2 1 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.20 EMR63013.1 - 0.013 14.9 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase SET PF00856.28 EMR63015.1 - 2.6e-10 40.9 0.0 4.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 SET domain Abhydrolase_6 PF12697.7 EMR63016.1 - 4.1e-06 27.6 0.0 4.4e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.7 EMR63017.1 - 7.6e-75 247.5 21.0 2e-11 44.3 0.3 10.3 4 2 4 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR63017.1 - 1.3e-61 204.2 14.2 2.8e-11 43.7 0.0 13.7 9 4 5 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR63017.1 - 5.1e-42 137.0 25.6 0.0018 18.6 0.0 19.8 20 0 0 20 20 20 8 Ankyrin repeat Ank_5 PF13857.6 EMR63017.1 - 3.7e-40 135.4 23.6 1.3e-05 25.3 0.1 14.0 7 3 6 14 14 14 11 Ankyrin repeats (many copies) Ank PF00023.30 EMR63017.1 - 6.6e-36 121.2 44.8 0.00033 21.0 0.1 17.6 18 1 0 18 18 18 10 Ankyrin repeat AAA_22 PF13401.6 EMR63017.1 - 3.2e-05 24.2 0.0 0.0014 18.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain Abhydrolase_6 PF12697.7 EMR63017.1 - 0.00073 20.2 0.0 0.0035 18.0 0.0 2.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.6 EMR63017.1 - 0.0022 18.4 0.0 0.011 16.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Hydrolase_4 PF12146.8 EMR63017.1 - 0.0082 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EMR63017.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 EMR63017.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein 4HBT_3 PF13622.6 EMR63018.1 - 1.9e-29 103.7 0.0 2.4e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMR63018.1 - 0.00014 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioesterase Glyco_hydro_20 PF00728.22 EMR63020.1 - 2.9e-87 293.3 0.0 3.7e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EMR63020.1 - 6.9e-27 94.8 0.2 2.1e-26 93.2 0.2 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EMR63020.1 - 0.0003 21.5 0.3 0.002 18.9 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Aldedh PF00171.22 EMR63021.1 - 6.3e-182 605.2 0.0 7.1e-182 605.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACOX PF01756.19 EMR63022.1 - 3.7e-48 163.5 0.1 9.8e-48 162.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EMR63022.1 - 6.2e-14 52.6 0.0 1.2e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EMR63022.1 - 1e-08 35.2 0.0 4.2e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EMR63022.1 - 0.0064 16.7 2.8 0.046 13.9 2.8 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMR63022.1 - 0.12 13.1 0.1 0.59 10.8 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Glyco_hydro_61 PF03443.14 EMR63023.1 - 1.9e-61 207.6 0.1 2.3e-61 207.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cerato-platanin PF07249.12 EMR63024.1 - 9.8e-08 32.1 1.4 2.7e-07 30.7 0.1 2.0 2 0 0 2 2 2 1 Cerato-platanin BHD_3 PF10405.9 EMR63025.1 - 1.1e-25 89.9 0.0 1.7e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EMR63025.1 - 8.1e-22 76.8 0.0 1.5e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EMR63025.1 - 2.8e-17 63.4 0.1 2.8e-17 63.4 0.1 2.5 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 EMR63025.1 - 0.037 13.7 0.1 0.075 12.7 0.1 1.6 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain VHS PF00790.19 EMR63026.1 - 1.9e-23 82.9 0.0 3.7e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EMR63026.1 - 7.7e-07 29.3 0.3 2e-06 28.0 0.3 1.7 1 0 0 1 1 1 1 GAT domain PhoU PF01895.19 EMR63026.1 - 0.0064 16.9 0.5 4.2 7.9 0.1 2.5 2 0 0 2 2 2 2 PhoU domain SR-25 PF10500.9 EMR63026.1 - 0.46 10.1 16.7 0.69 9.5 16.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Abhydrolase_3 PF07859.13 EMR63027.1 - 3.7e-21 75.9 0.1 5.5e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tyrosinase PF00264.20 EMR63028.1 - 1.3e-23 84.5 0.3 2e-23 83.9 0.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EMR63028.1 - 1.7e-09 38.3 0.0 1.9e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 Tyosinase C-terminal domain Abhydrolase_3 PF07859.13 EMR63029.1 - 0.0022 17.9 0.0 0.0054 16.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EMR63029.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DHDPS PF00701.22 EMR63030.1 - 4.5e-35 120.8 0.0 6.3e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family IU_nuc_hydro PF01156.19 EMR63030.1 - 0.052 13.1 0.1 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 Inosine-uridine preferring nucleoside hydrolase ABC_tran PF00005.27 EMR63032.1 - 2.3e-46 157.7 0.2 1.1e-24 87.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMR63032.1 - 6.9e-21 75.3 6.7 2e-05 24.6 0.0 4.6 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EMR63032.1 - 1.9e-11 43.7 10.3 1.9e-11 43.7 10.3 3.1 3 1 1 4 4 4 1 ABC-2 family transporter protein AAA_29 PF13555.6 EMR63032.1 - 2.9e-08 33.3 1.7 0.002 17.8 0.5 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 EMR63032.1 - 7.9e-08 32.0 0.8 0.28 10.6 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMR63032.1 - 0.00022 21.8 6.0 0.082 13.4 0.2 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EMR63032.1 - 0.00032 20.7 0.9 0.33 10.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF4162 PF13732.6 EMR63032.1 - 0.00073 20.2 0.0 0.2 12.4 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4162) AAA_27 PF13514.6 EMR63032.1 - 0.0023 17.6 0.4 0.55 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMR63032.1 - 0.0024 17.6 0.4 2.1 8.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EMR63032.1 - 0.0042 16.9 0.0 4.4 6.9 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 EMR63032.1 - 0.0044 17.4 0.8 2.4 8.5 0.4 2.5 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 EMR63032.1 - 0.032 13.9 0.4 7.4 6.2 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 EMR63032.1 - 0.095 12.6 0.0 13 5.6 0.0 2.8 3 0 0 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EMR63032.1 - 0.14 11.4 0.3 10 5.3 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.22 EMR63032.1 - 0.18 12.2 0.0 38 4.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MukB PF04310.12 EMR63032.1 - 0.22 11.3 0.6 17 5.2 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_22 PF13401.6 EMR63032.1 - 0.23 11.8 0.3 34 4.7 0.2 2.9 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EMR63032.1 - 0.27 9.8 0.1 2.3 6.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EMR63032.1 - 0.32 11.0 1.3 25 4.9 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 EMR63032.1 - 0.33 10.3 1.1 35 3.7 0.1 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FAD_binding_4 PF01565.23 EMR63033.1 - 1.4e-16 60.5 0.0 3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Amidase PF01425.21 EMR63034.1 - 5.6e-79 266.2 0.2 7.8e-79 265.7 0.2 1.2 1 0 0 1 1 1 1 Amidase INCENP_ARK-bind PF03941.15 EMR63035.1 - 1.1e-19 70.1 0.5 1.1e-19 70.1 0.5 3.1 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region UPF0147 PF03685.13 EMR63035.1 - 0.035 14.1 2.1 0.043 13.9 0.4 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) PTS_2-RNA PF01885.16 EMR63036.1 - 6.7e-61 205.5 0.0 8.6e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.17 EMR63036.1 - 0.06 13.4 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 La domain Transferase PF02458.15 EMR63037.1 - 1.3e-14 53.7 0.0 1.9e-13 49.9 0.0 2.0 1 1 0 1 1 1 1 Transferase family Mob1_phocein PF03637.17 EMR63038.1 - 3.3e-55 186.7 0.0 3.6e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Mito_carr PF00153.27 EMR63039.1 - 5.3e-17 61.5 3.1 3.1e-16 59.1 0.3 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Fungal_trans PF04082.18 EMR63041.1 - 5.4e-30 104.3 0.0 1e-29 103.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tautomerase_3 PF14832.6 EMR63042.1 - 2.3e-21 76.5 0.1 2.5e-21 76.3 0.1 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme ADH_zinc_N PF00107.26 EMR63043.1 - 2.3e-14 53.5 0.1 4.4e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR63043.1 - 3.2e-09 37.9 0.1 5.3e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR63043.1 - 1.4e-06 28.2 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PigN PF04987.14 EMR63044.1 - 1.6e-113 380.0 39.1 1.8e-79 267.7 19.1 3.8 2 1 1 3 3 3 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EMR63044.1 - 1.1e-10 41.6 3.9 5e-09 36.2 3.5 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMR63044.1 - 7.6e-08 32.1 0.5 1.2e-07 31.4 0.5 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EMR63044.1 - 5.9e-05 22.6 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Tetraspanin PF00335.20 EMR63044.1 - 0.18 11.5 0.7 0.56 9.9 0.7 1.9 1 0 0 1 1 1 0 Tetraspanin family Peptidase_S8 PF00082.22 EMR63045.1 - 5.2e-52 177.0 1.8 8.4e-52 176.3 1.8 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EMR63045.1 - 1.3e-16 61.3 0.1 2.3e-16 60.5 0.1 1.4 1 0 0 1 1 1 1 Fn3-like domain FixG_C PF11614.8 EMR63045.1 - 0.033 14.4 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF916 PF06030.12 EMR63045.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) DUF11 PF01345.18 EMR63045.1 - 0.079 13.3 0.5 0.32 11.3 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF11 DUF1682 PF07946.14 EMR63046.1 - 0.097 11.9 0.6 0.15 11.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LRIF1 PF15741.5 EMR63046.1 - 0.15 10.6 4.1 0.2 10.2 4.1 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 YjbR PF04237.13 EMR63047.1 - 0.083 13.5 0.0 0.12 13.0 0.0 1.3 1 1 0 1 1 1 0 YjbR TPR_2 PF07719.17 EMR63047.1 - 0.2 11.8 1.0 11 6.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Hemerythrin PF01814.23 EMR63048.1 - 1.4e-08 35.4 0.9 1.4e-08 35.4 0.9 1.4 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain VSP PF03302.13 EMR63049.1 - 0.016 14.1 4.8 0.021 13.7 4.8 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SCF PF02404.15 EMR63049.1 - 0.15 11.3 1.8 0.21 10.9 1.8 1.1 1 0 0 1 1 1 0 Stem cell factor PRR18 PF15671.5 EMR63049.1 - 0.35 10.7 12.2 0.54 10.1 12.2 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 SKG6 PF08693.10 EMR63049.1 - 0.46 9.9 4.1 1.2 8.6 4.1 1.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Apt1 PF10351.9 EMR63049.1 - 0.99 8.2 4.1 1.2 7.9 4.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Vps26 PF03643.15 EMR63051.1 - 3.6e-21 75.4 0.0 4.1e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EMR63051.1 - 0.025 14.6 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Ribosomal_L6 PF00347.23 EMR63052.1 - 1.5e-26 92.8 8.3 3.7e-14 53.1 2.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 TRI12 PF06609.13 EMR63053.1 - 3e-21 75.5 9.6 3.6e-21 75.2 9.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EMR63053.1 - 8.8e-08 31.4 12.8 8.8e-08 31.4 12.8 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MNSV_P7B PF06692.11 EMR63053.1 - 0.045 13.8 0.4 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Fer4_23 PF18009.1 EMR63055.1 - 0.11 12.9 0.3 0.59 10.6 0.1 1.9 2 0 0 2 2 2 0 4Fe-4S iron-sulfur cluster binding domain MIT_C PF16565.5 EMR63056.1 - 0.026 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT adh_short_C2 PF13561.6 EMR63057.1 - 1.8e-51 175.0 0.3 2.4e-51 174.6 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR63057.1 - 1.1e-41 142.5 0.1 1.4e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR63057.1 - 3.3e-16 59.7 0.4 5.5e-16 59.0 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR63057.1 - 0.0014 18.1 0.1 0.002 17.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 EMR63057.1 - 0.0079 16.1 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 YjeF-related protein N-terminus RmlD_sub_bind PF04321.17 EMR63057.1 - 0.0081 15.3 0.7 0.013 14.7 0.7 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EMR63057.1 - 0.06 12.7 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SRP14 PF02290.15 EMR63059.1 - 6.4e-30 103.4 0.0 9.1e-30 102.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein MIF4G PF02854.19 EMR63060.1 - 3e-16 59.7 0.0 5.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EMR63060.1 - 6e-05 23.0 0.0 0.0002 21.3 0.0 1.9 2 0 0 2 2 2 1 MA3 domain RRM_1 PF00076.22 EMR63061.1 - 1.7e-43 146.3 0.0 1.7e-17 63.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EMR63061.1 - 0.00073 19.5 0.0 3.8 7.6 0.0 3.1 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.10 EMR63061.1 - 0.008 15.8 0.0 1.4 8.4 0.0 3.6 4 0 0 4 4 4 1 ATP-grasp domain RRM_5 PF13893.6 EMR63061.1 - 0.0097 15.5 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EMR63061.1 - 0.021 14.9 0.0 10 6.3 0.0 3.4 3 1 0 3 3 3 0 Limkain b1 MFS_1 PF07690.16 EMR63062.1 - 3e-18 65.9 55.3 2.8e-09 36.4 29.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily KR PF08659.10 EMR63063.1 - 3.6e-39 134.5 0.1 7.5e-39 133.5 0.1 1.6 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 EMR63063.1 - 4.8e-24 85.3 1.6 6.8e-17 61.9 0.0 3.8 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR63063.1 - 1.6e-13 50.7 0.0 4.6e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 EMR63063.1 - 2.4e-12 47.0 0.0 5.5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR63063.1 - 1.2e-06 29.6 0.0 2.8e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR63063.1 - 2.6e-05 24.0 0.2 6e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EMR63063.1 - 0.00052 19.5 0.0 0.0015 18.0 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase MiAMP1 PF09117.10 EMR63064.1 - 3.2e-05 24.1 0.7 0.022 15.0 0.0 2.2 2 0 0 2 2 2 2 MiAMP1 SMP PF04927.12 EMR63065.1 - 1.1e-06 29.0 1.6 1.7e-06 28.4 1.6 1.3 1 0 0 1 1 1 1 Seed maturation protein PIN_5 PF08745.11 EMR63066.1 - 0.062 12.7 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 PINc domain ribonuclease Sulfotransfer_4 PF17784.1 EMR63068.1 - 5.7e-54 183.2 0.0 6.7e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain GAS2 PF02187.17 EMR63068.1 - 0.012 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Sulfotransfer_3 PF13469.6 EMR63068.1 - 0.1 13.0 0.2 0.75 10.1 0.0 2.2 1 1 0 2 2 2 0 Sulfotransferase family LysM PF01476.20 EMR63069.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 LysM domain Epimerase PF01370.21 EMR63070.1 - 9.4e-10 38.4 0.0 1.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMR63070.1 - 2.8e-05 23.4 1.1 5.5e-05 22.5 0.2 1.7 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EMR63070.1 - 5.3e-05 22.8 2.3 0.00098 18.6 2.3 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase ProRS-C_1 PF09180.11 EMR63071.1 - 8.2e-24 83.6 0.1 2e-23 82.4 0.1 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EMR63071.1 - 5.8e-19 68.8 0.0 1.1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMR63071.1 - 1.1e-16 60.7 0.0 2.7e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain ABC_membrane PF00664.23 EMR63072.1 - 2.7e-84 283.1 25.3 3.4e-48 164.7 1.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMR63072.1 - 8.3e-66 220.7 0.0 3.2e-32 111.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMR63072.1 - 2e-13 50.3 5.2 0.00019 20.9 0.1 4.4 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMR63072.1 - 4.3e-09 36.0 0.6 0.0037 17.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 EMR63072.1 - 4.6e-06 26.9 1.0 0.00097 19.3 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 EMR63072.1 - 5.5e-06 25.8 0.1 0.019 14.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EMR63072.1 - 5.8e-06 26.3 0.0 0.094 12.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EMR63072.1 - 1.1e-05 25.3 0.8 0.038 13.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EMR63072.1 - 2.7e-05 24.4 0.0 0.066 13.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 EMR63072.1 - 0.0001 22.7 4.4 0.058 13.8 0.2 3.1 3 2 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 EMR63072.1 - 0.00018 22.1 0.0 0.34 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EMR63072.1 - 0.00036 20.5 0.0 1.6 8.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 EMR63072.1 - 0.0004 19.7 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 EMR63072.1 - 0.00048 19.7 1.8 0.93 9.0 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 EMR63072.1 - 0.00064 20.3 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EMR63072.1 - 0.00098 18.9 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain PRK PF00485.18 EMR63072.1 - 0.00099 18.9 0.2 1.4 8.6 0.0 2.6 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 EMR63072.1 - 0.0019 18.1 4.2 1.7 8.3 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system CbiA PF01656.23 EMR63072.1 - 0.0029 17.6 0.0 0.11 12.6 0.0 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SbcCD_C PF13558.6 EMR63072.1 - 0.0065 16.7 2.1 10 6.5 0.0 4.3 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 EMR63072.1 - 0.0094 15.3 0.0 3.7 6.9 0.0 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 EMR63072.1 - 0.012 15.5 0.2 1.8 8.4 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Ploopntkinase3 PF18751.1 EMR63072.1 - 0.019 14.9 0.2 7 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 EMR63072.1 - 0.02 15.0 1.4 5.7 7.1 0.1 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EMR63072.1 - 0.02 14.1 0.2 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF3987 PF13148.6 EMR63072.1 - 0.023 13.7 0.0 0.57 9.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 EMR63072.1 - 0.025 14.3 0.0 0.89 9.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMR63072.1 - 0.085 13.0 0.9 9.2 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dala_Dala_lig_N PF01820.21 EMR63072.1 - 0.089 13.3 0.0 1.6 9.2 0.0 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus SRP54 PF00448.22 EMR63072.1 - 0.13 11.9 0.3 8.8 5.9 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 EMR63072.1 - 0.14 12.6 0.0 14 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMR63072.1 - 0.19 12.2 0.1 35 4.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 EMR63072.1 - 0.22 11.5 0.0 2.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 EMR63072.1 - 0.31 10.7 1.4 20 4.7 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain GMC_oxred_N PF00732.19 EMR63073.1 - 3.4e-30 105.5 0.0 3e-28 99.0 0.0 2.7 1 1 1 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR63073.1 - 4.5e-30 105.1 0.0 7e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EMR63073.1 - 0.00052 19.3 0.0 0.00094 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR63073.1 - 0.00062 19.0 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMR63073.1 - 0.0061 15.3 0.0 0.0098 14.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EMR63073.1 - 0.024 14.9 0.1 0.077 13.2 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR63073.1 - 0.032 13.5 0.8 0.58 9.3 0.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR63073.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NPP1 PF05630.11 EMR63075.1 - 3e-34 118.9 0.0 1.9e-20 73.8 0.0 2.1 1 1 1 2 2 2 2 Necrosis inducing protein (NPP1) LppA PF16708.5 EMR63075.1 - 0.034 14.1 0.1 0.098 12.6 0.0 1.8 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium HET PF06985.11 EMR63076.1 - 6.4e-13 49.3 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ANAPC_CDC26 PF10471.9 EMR63077.1 - 1.2 10.0 5.0 0.45 11.4 0.3 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 MARVEL PF01284.23 EMR63078.1 - 0.00024 21.1 9.9 0.00037 20.5 9.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain ArsA_ATPase PF02374.15 EMR63078.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase TraG_N PF07916.11 EMR63078.1 - 1.8 7.4 11.9 2.1 7.1 11.9 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2070 PF09843.9 EMR63078.1 - 4 5.6 7.0 5 5.3 7.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2975 PF11188.8 EMR63078.1 - 9.9 6.1 11.8 1.3 8.9 5.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF780 PF05611.11 EMR63079.1 - 0.5 11.2 5.9 0.37 11.6 4.2 1.7 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) SET PF00856.28 EMR63080.1 - 0.0012 19.2 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EMR63080.1 - 0.12 13.1 0.0 0.36 11.5 0.0 1.9 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding MMR_HSR1_C PF08438.10 EMR63081.1 - 3.4e-34 117.8 0.0 5.8e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EMR63081.1 - 9.1e-22 77.3 0.0 2.5e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMR63081.1 - 5.6e-09 35.7 0.2 1.1e-07 31.5 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EMR63081.1 - 0.0016 18.0 0.1 0.73 9.3 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EMR63081.1 - 0.013 16.1 0.0 0.46 11.0 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 EMR63081.1 - 0.026 14.6 0.1 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 EMR63081.1 - 0.045 12.7 0.1 0.52 9.2 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EMR63081.1 - 0.047 13.6 0.2 7.2 6.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Ploopntkinase3 PF18751.1 EMR63081.1 - 0.087 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 EMR63081.1 - 0.12 12.1 0.1 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 EMR63081.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain KTI12 PF08433.10 EMR63081.1 - 0.17 11.3 0.0 0.83 9.1 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Glyco_tran_28_C PF04101.16 EMR63082.1 - 3.1e-14 53.3 0.0 2.6e-09 37.3 0.0 2.8 2 1 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.9 EMR63084.1 - 1.8e-48 164.2 0.2 1.8e-48 164.2 0.2 2.0 3 0 0 3 3 3 1 Mitochondrial ribosomal subunit protein Ribosomal_L18 PF17135.4 EMR63086.1 - 3.2e-93 310.3 3.7 3.6e-93 310.2 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EMR63086.1 - 0.0082 16.8 0.1 0.026 15.2 0.1 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Aldo_ket_red PF00248.21 EMR63087.1 - 2e-66 224.2 0.0 2.3e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UTP15_C PF09384.10 EMR63088.1 - 1e-49 168.0 0.0 1.5e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EMR63088.1 - 4.3e-18 65.3 2.4 0.00024 21.8 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR63088.1 - 1.1e-05 25.6 0.1 0.51 10.7 0.0 3.9 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EMR63089.1 - 4.2e-05 23.3 0.1 0.00013 21.7 0.1 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 EMR63090.1 - 1e-71 236.9 3.2 1.4e-23 82.6 0.1 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMR63090.1 - 0.00045 19.5 0.2 0.021 14.0 0.0 2.9 3 1 1 4 4 4 1 Gammaproteobacterial serine protease Oxidored_FMN PF00724.20 EMR63091.1 - 1.6e-77 261.1 0.0 1.8e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EMR63091.1 - 0.029 13.8 0.0 4.3 6.7 0.0 3.0 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Fungal_trans PF04082.18 EMR63092.1 - 1.5e-33 116.0 1.2 2.5e-33 115.2 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR63092.1 - 2.5e-08 33.9 14.4 5.1e-08 32.9 14.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1440 PF07274.12 EMR63092.1 - 0.062 13.6 1.3 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) bZIP_1 PF00170.21 EMR63092.1 - 7.6 6.7 7.3 0.18 11.9 0.6 1.8 2 0 0 2 2 2 0 bZIP transcription factor ECH_1 PF00378.20 EMR63093.1 - 3.9e-38 131.2 0.0 1.6e-37 129.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMR63093.1 - 1.9e-31 109.8 0.0 1.2e-28 100.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ADH_N PF08240.12 EMR63094.1 - 1.7e-09 37.5 0.3 3.7e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR63094.1 - 8.2e-07 29.1 0.1 2.2e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 EMR63095.1 - 9.2e-12 44.9 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EMR63095.1 - 0.009 16.0 0.0 0.028 14.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EMR63095.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase VWA PF00092.28 EMR63095.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 von Willebrand factor type A domain SCP_3 PF17844.1 EMR63096.1 - 0.028 14.2 0.2 0.052 13.3 0.2 1.4 1 0 0 1 1 1 0 Bacterial SCP ortholog CYYR1 PF10873.8 EMR63096.1 - 3.5 8.1 6.2 3.4 8.1 0.0 2.8 1 1 2 3 3 3 0 Cysteine and tyrosine-rich protein 1 SRAP PF02586.14 EMR63097.1 - 5.4e-81 271.3 0.0 8.9e-81 270.6 0.0 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Macoilin PF09726.9 EMR63097.1 - 7.2 5.0 10.4 12 4.4 10.4 1.2 1 0 0 1 1 1 0 Macoilin family zf-CCHC PF00098.23 EMR63098.1 - 3.9e-60 197.4 104.3 6.3e-07 29.2 1.8 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_4 PF14392.6 EMR63098.1 - 4.6e-10 39.1 66.0 0.11 12.3 0.7 11.3 11 0 0 11 11 11 9 Zinc knuckle zf-CCHC_2 PF13696.6 EMR63098.1 - 8e-06 25.6 86.8 0.0012 18.6 1.8 12.0 12 0 0 12 12 12 7 Zinc knuckle zf-CCHC_3 PF13917.6 EMR63098.1 - 2.1e-05 24.4 81.1 0.0048 16.8 1.7 10.8 3 3 8 11 11 11 9 Zinc knuckle zf-C2H2_10 PF16588.5 EMR63098.1 - 0.0011 18.6 3.6 0.0011 18.6 3.6 10.0 11 0 0 11 11 11 3 C2H2 zinc-finger zf-CCHC_6 PF15288.6 EMR63098.1 - 0.048 13.5 0.2 0.048 13.5 0.2 11.3 6 3 5 11 11 11 0 Zinc knuckle WD40 PF00400.32 EMR63099.1 - 6.8e-26 90.0 29.8 0.00021 22.0 0.3 10.0 10 1 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR63099.1 - 8.5e-14 51.6 5.4 0.0051 17.1 0.0 6.7 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR63099.1 - 8.4e-05 21.7 2.5 0.5 9.3 0.0 4.0 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EMR63099.1 - 0.033 14.1 0.6 5.7 7.0 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Inhibitor_I36 PF03995.13 EMR63099.1 - 0.08 12.9 0.8 0.71 9.8 0.3 2.7 2 0 0 2 2 2 0 Peptidase inhibitor family I36 Mcl1_mid PF12341.8 EMR63099.1 - 0.14 11.5 0.3 1.5 8.1 0.1 2.1 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Ank_2 PF12796.7 EMR63100.1 - 4.9e-43 145.6 0.6 1.7e-11 44.5 0.0 6.3 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR63100.1 - 8.2e-34 111.8 1.1 0.00034 20.8 0.0 10.3 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 EMR63100.1 - 2.7e-27 94.0 0.6 0.031 14.7 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 EMR63100.1 - 3.8e-27 94.3 1.2 3.5e-07 30.6 0.0 7.9 4 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR63100.1 - 8.2e-27 92.9 0.4 0.0058 16.9 0.0 8.9 4 3 5 9 9 9 6 Ankyrin repeats (many copies) SPRY PF00622.28 EMR63100.1 - 0.0045 17.1 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 SPRY domain Thr_synth_N PF14821.6 EMR63100.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonine synthase N terminus SRI PF08236.11 EMR63100.1 - 0.066 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain PDE4_UCR PF18100.1 EMR63100.1 - 0.066 13.9 0.0 0.18 12.5 0.0 1.7 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) WD40 PF00400.32 EMR63101.1 - 1.1e-46 155.8 22.1 3.3e-08 34.1 0.6 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat Tfb5 PF06331.12 EMR63101.1 - 1.3e-19 70.0 1.0 2.3e-19 69.1 1.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Nup160 PF11715.8 EMR63101.1 - 5.3e-08 32.0 0.7 0.0031 16.2 0.0 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EMR63101.1 - 1.6e-07 31.5 0.0 0.12 12.7 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EMR63101.1 - 0.0081 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 EMR63101.1 - 0.01 14.6 0.0 7 5.3 0.0 3.0 3 0 0 3 3 3 0 Nup133 N terminal like CHAP PF05257.16 EMR63101.1 - 0.086 13.4 0.0 1.5 9.4 0.0 2.5 2 0 0 2 2 2 0 CHAP domain STE PF02200.16 EMR63101.1 - 0.18 12.2 0.0 9.5 6.7 0.0 2.4 1 1 1 2 2 2 0 STE like transcription factor Ank_2 PF12796.7 EMR63102.1 - 5.3e-07 30.1 0.7 1.6e-06 28.6 0.2 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR63102.1 - 7.4e-06 26.4 1.2 0.015 15.9 0.0 4.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR63102.1 - 1.4e-05 25.3 1.1 0.011 16.1 0.3 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR63102.1 - 0.00013 22.1 0.0 0.023 15.2 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EMR63102.1 - 0.00013 22.2 4.1 0.3 11.6 0.0 3.9 4 1 0 4 4 4 2 Ankyrin repeat SepSecS PF05889.13 EMR63102.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Frataxin_Cyay PF01491.16 EMR63103.1 - 3.4e-24 85.0 0.0 4.1e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain DUF3632 PF12311.8 EMR63104.1 - 1.1e-37 130.2 0.2 1.3e-37 129.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) UPA PF17217.3 EMR63105.1 - 0.59 10.0 7.1 5.3 6.9 0.6 3.2 1 1 0 3 3 3 0 UPA domain Fic PF02661.18 EMR63106.1 - 8.2e-17 61.9 0.0 1.7e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family Glyco_transf_15 PF01793.16 EMR63106.1 - 0.031 13.5 0.1 0.061 12.6 0.0 1.6 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase DUF719 PF05334.13 EMR63106.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Pil1 PF13805.6 EMR63107.1 - 9.3e-126 418.7 0.2 1.2e-125 418.4 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 EMR63107.1 - 0.071 13.6 5.6 2 8.9 0.1 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region FlgN PF05130.12 EMR63107.1 - 0.98 9.9 5.9 1.7 9.2 0.6 3.0 3 1 0 3 3 3 0 FlgN protein SET PF00856.28 EMR63108.1 - 6.5e-19 68.9 1.0 6.6e-18 65.7 0.3 2.8 2 1 0 2 2 2 1 SET domain Abhydrolase_3 PF07859.13 EMR63110.1 - 7.2e-11 42.3 0.1 9.7e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR63110.1 - 4.3e-09 36.2 0.0 7.9e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EMR63110.1 - 4.8e-08 32.8 0.0 4.6e-05 23.1 0.0 2.9 3 0 0 3 3 3 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EMR63110.1 - 5.8e-05 22.5 0.1 0.064 12.5 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR63110.1 - 0.00068 19.3 0.1 0.051 13.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF829 PF05705.14 EMR63110.1 - 0.0094 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) BAAT_C PF08840.11 EMR63110.1 - 0.047 13.6 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 EMR63110.1 - 0.074 12.5 0.4 9.3 5.7 0.2 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF2048 PF09752.9 EMR63110.1 - 0.092 11.8 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_4 PF08386.10 EMR63110.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein SLT PF01464.20 EMR63111.1 - 9.6e-10 38.1 0.0 1.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain p450 PF00067.22 EMR63112.1 - 9.1e-05 21.4 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L44 PF00935.19 EMR63113.1 - 1.2e-36 125.0 11.0 1.7e-36 124.5 11.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.20 EMR63113.1 - 9.2 6.8 12.9 1.7 9.1 1.3 2.9 2 1 0 2 2 2 0 Ribosomal protein L33 Terpene_synth_C PF03936.16 EMR63114.1 - 8.7e-08 31.8 0.0 1.2e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Ctr PF04145.15 EMR63115.1 - 1.4e-30 106.8 0.3 1.7e-30 106.6 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Cytadhesin_P30 PF07271.11 EMR63115.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 MFS_1 PF07690.16 EMR63116.1 - 5.8e-22 78.1 56.3 5.9e-16 58.3 39.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp PF00026.23 EMR63118.1 - 3.2e-63 214.0 0.4 5.4e-63 213.3 0.4 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR63118.1 - 1.1e-11 45.3 0.6 4.7e-11 43.2 0.6 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMR63118.1 - 0.08 13.6 0.1 22 5.8 0.1 3.0 2 1 0 2 2 2 0 Aspartyl protease FMO-like PF00743.19 EMR63119.1 - 5.2e-26 91.2 0.0 1.1e-10 40.6 0.0 3.2 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMR63119.1 - 9.6e-09 34.9 0.0 2.5e-07 30.2 0.0 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR63119.1 - 1.6e-08 34.2 0.0 1e-05 25.0 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR63119.1 - 4e-08 32.8 0.1 0.16 11.1 0.0 3.9 4 0 0 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMR63119.1 - 3e-05 24.0 0.1 0.00098 19.1 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMR63119.1 - 0.00056 20.1 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 EMR63119.1 - 0.025 14.1 0.0 0.076 12.5 0.0 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus DUF3322 PF11795.8 EMR63119.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Thi4 PF01946.17 EMR63119.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 EMR63119.1 - 0.22 11.6 0.2 0.82 9.7 0.1 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cornichon PF03311.14 EMR63120.1 - 1.3e-50 170.8 12.1 1.5e-50 170.6 12.1 1.0 1 0 0 1 1 1 1 Cornichon protein Ribosomal_S8 PF00410.19 EMR63121.1 - 1.9e-07 31.0 0.0 8.6e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 DUF5558 PF17713.1 EMR63121.1 - 0.16 12.3 1.2 0.31 11.4 1.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5558) GlcNAc-1_reg PF18440.1 EMR63122.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain Dabb PF07876.12 EMR63123.1 - 1.4e-18 67.3 0.0 1.6e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aminotran_1_2 PF00155.21 EMR63124.1 - 1.4e-40 139.6 0.0 2.2e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMR63124.1 - 3.5e-07 29.1 0.0 5.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMR63124.1 - 1.1e-06 27.9 0.0 2.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMR63124.1 - 9.6e-06 25.1 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 EMR63124.1 - 3.5e-05 22.8 0.0 5.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 EMR63124.1 - 0.0039 16.6 0.1 0.006 15.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 EMR63124.1 - 0.084 11.7 0.0 0.35 9.7 0.0 1.8 2 0 0 2 2 2 0 Allinase WD40 PF00400.32 EMR63125.1 - 6.5e-33 112.2 9.3 3.8e-06 27.5 0.0 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR63125.1 - 1.5e-15 57.3 0.0 2.8e-06 27.5 0.0 3.8 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR63125.1 - 0.004 16.1 4.8 1 8.2 0.0 3.9 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EMR63125.1 - 0.057 12.1 0.9 1.1 7.8 0.0 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Dmrt1 PF12374.8 EMR63126.1 - 5.3 7.5 10.0 3.6 8.1 6.1 2.5 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 ABC2_membrane PF01061.24 EMR63127.1 - 2.7e-38 131.5 20.2 5.6e-38 130.5 20.2 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EMR63127.1 - 1.5e-24 87.1 0.0 3.1e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMR63127.1 - 2e-05 24.6 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMR63127.1 - 0.0053 16.5 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 EMR63127.1 - 0.0078 15.4 34.3 0.0073 15.5 28.6 2.3 1 1 1 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EMR63127.1 - 0.021 14.8 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC2_membrane_2 PF12679.7 EMR63127.1 - 0.029 13.7 18.0 5.9 6.1 18.0 2.3 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_16 PF13191.6 EMR63127.1 - 0.043 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EMR63127.1 - 0.057 14.0 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMR63127.1 - 0.06 13.8 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMR63127.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMR63127.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PDR_CDR PF06422.12 EMR63127.1 - 0.26 11.2 1.5 1.5 8.8 0.2 2.8 2 0 0 2 2 2 0 CDR ABC transporter SurE PF01975.17 EMR63128.1 - 8.1e-38 130.2 0.0 1.1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE NGP1NT PF08153.12 EMR63129.1 - 2.1e-49 167.0 0.6 3.5e-49 166.3 0.6 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EMR63129.1 - 1.8e-17 63.5 0.0 2.7e-13 50.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EMR63129.1 - 5e-05 22.9 0.1 0.0006 19.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EMR63129.1 - 0.00029 20.9 0.1 0.78 9.8 0.0 3.4 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 EMR63129.1 - 0.00079 19.4 0.1 0.068 13.1 0.0 2.8 2 1 0 2 2 2 1 RsgA GTPase Arf PF00025.21 EMR63129.1 - 0.001 18.6 0.2 0.35 10.3 0.0 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMR63129.1 - 0.0015 18.1 0.1 0.11 12.0 0.0 3.0 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain PAN_4 PF14295.6 EMR63130.1 - 9.7e-06 25.4 2.6 3e-05 23.8 2.6 1.9 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EMR63130.1 - 0.002 18.1 0.3 0.0049 16.8 0.3 1.6 1 0 0 1 1 1 1 PAN domain FMN_red PF03358.15 EMR63131.1 - 6.3e-11 42.2 0.0 8.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMR63131.1 - 6.1e-07 29.4 0.0 7.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EMR63131.1 - 8.8e-05 22.7 0.1 0.00052 20.2 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EMR63131.1 - 0.00057 20.1 0.0 0.0087 16.3 0.0 2.1 1 1 1 2 2 2 1 Flavodoxin domain G_glu_transpept PF01019.21 EMR63132.1 - 1.2e-169 565.4 0.2 1.4e-169 565.2 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase But2 PF09792.9 EMR63133.1 - 4.4e-19 69.3 0.1 6.6e-19 68.7 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain GLTT PF01744.20 EMR63135.1 - 1.3e-06 28.0 7.9 1.3e-06 28.0 7.9 2.8 3 1 0 3 3 3 1 GLTT repeat (6 copies) TFIIA PF03153.13 EMR63135.1 - 2.4 8.1 6.8 3.7 7.4 6.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exo_endo_phos PF03372.23 EMR63136.1 - 1.4e-05 24.7 1.6 5.2e-05 22.9 1.6 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Epimerase PF01370.21 EMR63137.1 - 1.1e-09 38.1 0.1 9.2e-08 31.8 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR63137.1 - 0.00038 20.4 0.1 0.00068 19.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EMR63137.1 - 0.11 13.1 0.2 0.36 11.4 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 EMR63137.1 - 0.16 11.5 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EMR63137.1 - 0.32 10.4 0.4 0.54 9.6 0.1 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MSP1a PF11670.8 EMR63138.1 - 0.32 10.3 2.3 0.35 10.1 2.3 1.0 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Mucin PF01456.17 EMR63138.1 - 1.6 8.7 10.6 1.8 8.5 10.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein GTP_EFTU PF00009.27 EMR63139.1 - 1e-58 198.1 0.3 2.1e-58 197.1 0.2 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EMR63139.1 - 8.3e-33 112.7 0.0 1.8e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EMR63139.1 - 2.5e-31 107.6 0.0 4.8e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EMR63139.1 - 1.2e-23 83.0 0.0 3e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMR63139.1 - 3.4e-14 53.0 0.0 7.8e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EMR63139.1 - 7.6e-07 29.0 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF442 PF04273.13 EMR63139.1 - 0.014 15.5 0.0 0.26 11.4 0.0 2.9 2 0 0 2 2 2 0 Putative phosphatase (DUF442) MMR_HSR1 PF01926.23 EMR63139.1 - 0.036 14.1 0.1 0.074 13.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M24 PF00557.24 EMR63141.1 - 2e-46 158.3 0.0 2.5e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EMR63141.1 - 1.7e-20 73.0 7.5 1.7e-20 73.0 7.5 2.1 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EMR63141.1 - 0.00058 19.9 5.6 0.00058 19.9 5.6 2.3 2 0 0 2 2 2 1 MYND finger CR6_interact PF10147.9 EMR63142.1 - 0.003 17.3 4.1 0.006 16.3 4.1 1.5 1 1 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Protocadherin PF08374.11 EMR63142.1 - 0.013 15.5 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Protocadherin DUF2681 PF10883.8 EMR63142.1 - 0.025 15.0 1.2 0.39 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) EphA2_TM PF14575.6 EMR63142.1 - 0.068 14.0 0.0 0.17 12.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 EMR63142.1 - 0.14 13.2 0.8 0.28 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) LcrG PF07216.12 EMR63142.1 - 0.14 12.0 6.9 0.31 11.0 5.4 2.1 2 0 0 2 2 2 0 LcrG protein Shisa PF13908.6 EMR63142.1 - 0.16 12.2 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Iso_dh PF00180.20 EMR63143.1 - 4.8e-96 321.9 0.0 8.9e-96 321.1 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase A_deamin PF02137.18 EMR63144.1 - 4.4e-23 82.3 0.0 1.2e-21 77.6 0.0 2.7 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain DASH_Dad2 PF08654.10 EMR63148.1 - 0.026 14.9 1.5 0.21 12.0 0.0 3.0 2 1 0 3 3 3 0 DASH complex subunit Dad2 HalX PF08663.10 EMR63148.1 - 0.12 12.7 2.1 0.4 11.0 0.4 2.6 2 0 0 2 2 2 0 HalX domain Antimicrobial_3 PF08025.11 EMR63148.1 - 0.12 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Spider antimicrobial peptide Med9 PF07544.13 EMR63148.1 - 0.47 10.6 4.6 15 5.8 0.0 4.0 4 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 PHD PF00628.29 EMR63148.1 - 2.1 8.3 10.3 3.6 7.6 9.9 1.6 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 EMR63149.1 - 4.7e-08 32.8 13.4 8.2e-08 32.0 13.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.25 EMR63149.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase SDA1 PF05285.12 EMR63149.1 - 0.18 11.2 9.7 0.29 10.5 9.7 1.4 1 0 0 1 1 1 0 SDA1 Prok-RING_4 PF14447.6 EMR63149.1 - 0.29 11.0 13.3 0.51 10.3 13.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TIMELESS_C PF05029.13 EMR63149.1 - 2.1 7.4 11.6 3.7 6.6 11.6 1.3 1 0 0 1 1 1 0 Timeless protein C terminal region FAM24 PF15193.6 EMR63149.1 - 4.5 8.1 6.4 11 6.9 6.4 1.5 1 0 0 1 1 1 0 FAM24 family zf-C2H2_2 PF12756.7 EMR63150.1 - 3.5e-25 88.3 5.0 3.5e-25 88.3 5.0 1.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Thioredoxin_2 PF13098.6 EMR63150.1 - 0.048 14.1 0.5 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like domain zf-C2H2_jaz PF12171.8 EMR63150.1 - 0.12 12.7 0.5 0.12 12.7 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Androgen_recep PF02166.16 EMR63150.1 - 0.31 9.8 10.4 0.45 9.3 10.4 1.2 1 0 0 1 1 1 0 Androgen receptor DUF2024 PF09630.10 EMR63150.1 - 0.47 10.4 3.5 2.5 8.0 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) RNase_PH PF01138.21 EMR63151.1 - 1.8e-28 99.7 0.1 4.1e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 tRNA_int_endo PF01974.17 EMR63152.1 - 8e-12 45.1 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Suf PF05843.14 EMR63152.1 - 0.41 10.6 3.9 0.59 10.1 3.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DTHCT PF08070.11 EMR63152.1 - 1.2 9.9 10.3 1.3 9.8 8.7 1.8 1 1 1 2 2 2 0 DTHCT (NUC029) region FmiP_Thoc5 PF09766.9 EMR63153.1 - 3.6e-32 112.1 12.0 4.7e-32 111.7 12.0 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SusD_RagB PF07980.11 EMR63153.1 - 0.05 13.2 1.7 0.066 12.8 1.7 1.1 1 0 0 1 1 1 0 SusD family CENP-F_leu_zip PF10473.9 EMR63153.1 - 0.28 11.2 12.5 0.57 10.2 5.9 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SPATA1_C PF15743.5 EMR63153.1 - 1.2 9.2 13.0 0.05 13.7 5.5 2.1 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus DUF3958 PF13125.6 EMR63153.1 - 2.4 8.4 15.2 4.4 7.6 8.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) DOR PF14839.6 EMR63153.1 - 3.4 7.5 5.6 1.1 9.2 1.4 1.9 2 0 0 2 2 2 0 DOR family Casc1_N PF15927.5 EMR63153.1 - 5.1 6.7 16.1 0.071 12.8 7.5 2.0 2 1 1 3 3 3 0 Cancer susceptibility candidate 1 N-terminus YabA PF06156.13 EMR63153.1 - 9.6 6.9 8.9 17 6.1 0.4 2.3 2 0 0 2 2 2 0 Initiation control protein YabA RabGAP-TBC PF00566.18 EMR63154.1 - 4.4e-30 105.0 0.0 1.5e-25 90.1 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ammonium_transp PF00909.21 EMR63155.1 - 3.4e-113 378.4 29.5 3.9e-113 378.2 29.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HlyIII PF03006.20 EMR63156.1 - 9.9e-61 205.3 20.1 1.2e-60 205.0 20.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Fijivirus_P9-2 PF06837.11 EMR63156.1 - 0.094 12.2 4.2 0.18 11.3 4.2 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein Kinesin_assoc PF16183.5 EMR63157.1 - 0.29 11.2 1.6 17 5.5 0.0 2.8 3 0 0 3 3 3 0 Kinesin-associated Cwf_Cwc_15 PF04889.12 EMR63158.1 - 0.021 14.6 5.7 0.021 14.6 5.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 EMR63158.1 - 0.32 9.0 0.5 0.44 8.6 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 EMR63158.1 - 3.5 8.1 18.1 3.2 8.2 12.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SGT1 PF07093.11 EMR63158.1 - 4.7 5.5 4.8 7.5 4.9 4.8 1.2 1 0 0 1 1 1 0 SGT1 protein TauD PF02668.16 EMR63159.1 - 2e-11 44.2 0.3 2.5e-11 43.9 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EMR63159.1 - 0.031 13.4 0.4 0.039 13.1 0.4 1.1 1 0 0 1 1 1 0 CsiD Sulfate_transp PF00916.20 EMR63161.1 - 4e-107 358.3 22.1 4.9e-107 358.0 22.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMR63161.1 - 7.7e-09 35.2 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EMR63161.1 - 0.013 15.9 4.3 0.013 15.9 4.3 3.3 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily Yip1 PF04893.17 EMR63162.1 - 9.5e-13 48.2 14.4 1.3e-12 47.7 14.4 1.1 1 0 0 1 1 1 1 Yip1 domain DDDD PF10161.9 EMR63162.1 - 0.15 11.9 0.1 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Herpes_capsid PF06112.11 EMR63162.1 - 0.87 9.6 4.0 1.3 9.1 4.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RNA_pol_Rpb4 PF03874.16 EMR63163.1 - 1.1e-24 87.2 6.1 1.3e-24 86.9 6.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 EMR63163.1 - 0.021 14.5 1.3 0.027 14.1 1.3 1.1 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein TerB PF05099.13 EMR63163.1 - 0.045 13.7 0.4 0.088 12.8 0.4 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB RabGAP-TBC PF00566.18 EMR63164.1 - 1.7e-17 63.8 0.0 2.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PY_rept_46 PF09689.10 EMR63164.1 - 0.39 11.3 0.2 0.39 11.3 0.2 1.8 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) zf-RRN7 PF11781.8 EMR63165.1 - 0.00017 21.2 2.9 0.00033 20.3 2.9 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF35_N PF12172.8 EMR63165.1 - 0.025 14.5 0.2 0.025 14.5 0.2 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Arv1 PF04161.13 EMR63166.1 - 2.8e-77 259.6 0.0 3.3e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Arv1-like family TPR_10 PF13374.6 EMR63167.1 - 6.4e-08 32.2 0.1 1.8e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMR63167.1 - 1.2e-07 31.9 0.0 4.5e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat NB-ARC PF00931.22 EMR63167.1 - 1.7e-05 24.2 0.0 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EMR63167.1 - 0.0025 18.1 0.1 0.0079 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMR63167.1 - 0.0067 16.8 0.7 0.033 14.6 0.5 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EMR63167.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 EMR63167.1 - 0.15 11.2 0.0 8.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Anion-transporting ATPase NAT PF04768.13 EMR63168.1 - 4.2e-48 163.2 0.0 6.6e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Methyltransf_11 PF08241.12 EMR63169.1 - 1.5e-13 51.2 0.0 3.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR63169.1 - 3.3e-06 27.7 0.0 9e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR63169.1 - 0.00079 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR63169.1 - 0.0068 17.1 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR63169.1 - 0.24 10.7 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Sybindin PF04099.12 EMR63170.1 - 7.7e-49 165.3 0.0 9.7e-49 165.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EMR63170.1 - 1.8e-08 34.6 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Alk_phosphatase PF00245.20 EMR63171.1 - 4.5e-73 246.6 0.0 2.5e-36 125.5 0.3 2.1 1 1 1 2 2 2 2 Alkaline phosphatase Chorion_1 PF01723.16 EMR63171.1 - 0.82 9.6 4.2 5.2 7.0 0.8 2.3 2 0 0 2 2 2 0 Chorion protein Glycos_transf_4 PF00953.21 EMR63172.1 - 4e-33 114.7 9.8 4e-33 114.7 9.8 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 4 GCIP PF13324.6 EMR63172.1 - 0.23 11.0 0.2 0.37 10.4 0.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting ATP_synt_H PF05493.13 EMR63173.1 - 8.6e-25 87.0 1.7 9.6e-25 86.8 1.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit H ABC2_membrane_2 PF12679.7 EMR63173.1 - 0.011 15.0 1.4 0.013 14.8 1.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1129 PF06570.11 EMR63173.1 - 0.032 13.7 0.4 0.035 13.6 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 EMR63173.1 - 0.045 13.4 0.6 0.047 13.4 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Flavi_NS4A PF01350.17 EMR63173.1 - 0.12 12.3 0.5 0.14 12.0 0.5 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A DUF2206 PF09971.9 EMR63173.1 - 0.23 10.2 1.5 0.26 10.0 1.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) eIF-5a PF01287.20 EMR63174.1 - 6.4e-29 99.9 1.7 8.9e-29 99.4 1.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EMR63174.1 - 0.014 15.4 0.5 0.037 14.1 0.0 2.0 3 0 0 3 3 3 0 Elongation factor P (EF-P) KOW-like domain NAD_binding_2 PF03446.15 EMR63175.1 - 5.1e-29 101.5 0.3 8.6e-29 100.7 0.1 1.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMR63175.1 - 1.9e-09 37.8 0.1 3.3e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EMR63175.1 - 8.5e-09 35.6 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EMR63175.1 - 1.4e-08 35.2 0.1 3.3e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EMR63175.1 - 4.6e-06 26.9 0.1 8.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EMR63175.1 - 0.00025 21.3 0.3 0.00062 20.0 0.3 1.7 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.6 EMR63175.1 - 0.0042 17.0 0.6 0.0061 16.5 0.6 1.2 1 0 0 1 1 1 1 NAD(P)H-binding OCD_Mu_crystall PF02423.15 EMR63175.1 - 0.014 14.3 0.1 0.021 13.8 0.1 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 EMR63175.1 - 0.015 16.1 0.1 0.048 14.5 0.1 1.9 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Vps52 PF04129.12 EMR63176.1 - 3.5e-120 402.1 0.0 4.5e-120 401.8 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EMR63176.1 - 7.1e-06 24.7 2.8 5.4e-05 21.8 2.8 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 VWA_2 PF13519.6 EMR63178.1 - 6.6e-24 84.6 0.2 1.6e-23 83.4 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 EMR63178.1 - 4.1e-10 39.8 0.1 5.9e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 EMR63178.1 - 8e-09 36.0 0.1 1.2e-08 35.4 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 EMR63178.1 - 0.0072 16.2 1.1 0.022 14.6 1.1 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif GTP_EFTU PF00009.27 EMR63179.1 - 2.3e-34 118.6 1.3 3.5e-34 118.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EMR63179.1 - 3.5e-19 68.9 0.0 8.5e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EMR63179.1 - 4.3e-08 33.4 12.8 4.3e-08 33.4 0.4 3.8 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMR63179.1 - 8.1e-08 32.3 0.2 7.6e-06 26.0 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EMR63179.1 - 8.8e-08 32.0 2.4 1.7e-07 31.0 0.6 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Roc PF08477.13 EMR63179.1 - 0.00067 19.9 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EMR63179.1 - 0.017 14.9 0.0 0.017 14.9 0.0 2.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Ras PF00071.22 EMR63179.1 - 0.05 13.2 0.0 0.28 10.8 0.0 2.4 1 1 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 EMR63179.1 - 0.11 12.4 0.4 1.6 8.6 0.2 2.9 2 1 0 2 2 2 0 RsgA GTPase TrkA_C PF02080.21 EMR63179.1 - 0.17 11.7 1.3 2.8 7.8 0.1 3.0 3 0 0 3 3 3 0 TrkA-C domain Nbl1_Borealin_N PF10444.9 EMR63180.1 - 1.1e-20 72.9 6.4 1.8e-20 72.3 6.4 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Toxin_10 PF05431.11 EMR63180.1 - 3 7.3 5.6 4.5 6.7 5.6 1.3 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 Radical_SAM PF04055.21 EMR63181.1 - 1.8e-07 31.7 0.0 3.3e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EMR63181.1 - 5.7e-05 23.4 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMR63181.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain WD40 PF00400.32 EMR63182.1 - 8.2e-12 45.5 1.6 0.00035 21.3 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR63182.1 - 0.0026 18.0 0.1 20 5.5 0.0 4.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR63182.1 - 0.0051 15.8 0.1 2.4 7.0 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BNR PF02012.20 EMR63182.1 - 3.8 7.9 6.1 0.57 10.4 1.0 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat adh_short PF00106.25 EMR63183.1 - 7.6e-29 100.6 0.0 9.1e-29 100.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63183.1 - 7.3e-25 87.9 0.0 8.7e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR63183.1 - 4.2e-08 33.3 0.0 5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 KR domain HSP70 PF00012.20 EMR63184.1 - 2.3e-167 557.8 5.3 2.3e-167 557.8 5.3 2.3 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EMR63184.1 - 2.7e-11 42.9 0.0 1.6e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EMR63184.1 - 0.088 13.2 0.1 20 5.7 0.1 3.2 2 1 0 2 2 2 0 Cell division protein FtsA GMC_oxred_N PF00732.19 EMR63185.1 - 2.4e-68 230.7 0.0 3e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR63185.1 - 1.1e-27 97.3 0.0 1.9e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EMR63185.1 - 0.002 18.3 0.4 0.0045 17.2 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR63185.1 - 0.028 14.0 1.5 0.051 13.1 0.5 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EMR63185.1 - 0.052 12.8 0.1 0.085 12.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EMR63185.1 - 0.16 11.2 0.2 0.48 9.6 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR63185.1 - 0.17 10.9 1.2 0.84 8.6 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EMR63185.1 - 0.19 10.8 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ubiquitin PF00240.23 EMR63186.1 - 3.7e-34 116.3 0.6 4.8e-34 115.9 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EMR63186.1 - 1.8e-31 107.8 10.1 2.7e-31 107.2 10.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EMR63186.1 - 1.9e-15 56.4 0.5 2.6e-15 56.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMR63186.1 - 2.3e-05 24.7 0.1 9e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EMR63186.1 - 0.0037 17.6 0.1 0.0057 17.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EMR63186.1 - 0.0039 17.1 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMR63186.1 - 0.0086 16.2 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMR63186.1 - 0.029 14.9 0.1 0.034 14.7 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EMR63186.1 - 0.059 13.4 0.8 6.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Peptidase_S10 PF00450.22 EMR63187.1 - 3.9e-87 293.4 0.3 5.3e-87 292.9 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Aldo_ket_red PF00248.21 EMR63188.1 - 2e-38 132.3 0.0 5.1e-38 130.9 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family CRAL_TRIO PF00650.20 EMR63189.1 - 2.6e-22 79.2 0.0 7.4e-22 77.8 0.0 1.7 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMR63189.1 - 4.2e-11 42.9 0.0 9.1e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ThiF PF00899.21 EMR63190.1 - 3.8e-53 180.3 0.2 8.9e-53 179.1 0.2 1.5 1 1 0 1 1 1 1 ThiF family E2_bind PF08825.10 EMR63190.1 - 5.6e-29 100.1 0.1 1e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EMR63190.1 - 0.00044 20.3 1.3 0.00076 19.6 0.1 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 EMR63190.1 - 0.0019 18.7 0.1 0.01 16.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain E1_UFD PF09358.10 EMR63190.1 - 0.0062 17.2 0.0 0.021 15.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin fold domain DUF3419 PF11899.8 EMR63190.1 - 0.013 14.8 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Ecm33 PF12454.8 EMR63190.1 - 0.047 13.8 2.0 0.11 12.7 2.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Sacchrp_dh_NADP PF03435.18 EMR63190.1 - 0.063 13.5 0.1 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PglD_N PF17836.1 EMR63190.1 - 0.065 13.9 0.2 0.18 12.5 0.2 1.8 1 0 0 1 1 1 0 PglD N-terminal domain Pyr_redox PF00070.27 EMR63190.1 - 0.069 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EMR63190.1 - 0.096 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F-box PF00646.33 EMR63191.1 - 2.9e-08 33.4 1.8 3.1e-07 30.1 0.1 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EMR63191.1 - 1.7e-06 27.8 3.3 1.9e-05 24.5 0.4 2.6 2 0 0 2 2 2 2 F-box-like DUF5063 PF16702.5 EMR63192.1 - 0.014 15.8 1.5 0.018 15.4 1.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) DUF1523 PF07509.11 EMR63192.1 - 0.097 12.0 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Pex2_Pex12 PF04757.14 EMR63193.1 - 8.2e-50 169.5 1.7 1.1e-49 169.1 1.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EMR63193.1 - 0.0027 17.5 1.3 0.0041 16.9 1.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMR63193.1 - 0.025 14.4 2.1 0.043 13.6 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMR63193.1 - 0.029 14.7 2.8 0.049 14.0 2.8 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EMR63193.1 - 0.12 12.3 1.8 0.2 11.5 1.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMR63193.1 - 0.37 11.0 1.9 0.63 10.2 1.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Presenilin PF01080.17 EMR63194.1 - 4.5 5.9 4.0 4.9 5.8 4.0 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EMR63194.1 - 9.3 5.9 6.4 12 5.5 6.4 1.2 1 0 0 1 1 1 0 Connexin Glyoxalase PF00903.25 EMR63195.1 - 2.7e-06 27.6 5.6 1e-05 25.7 1.4 2.7 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_1 PF00515.28 EMR63195.1 - 0.15 11.9 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 EMR63196.1 - 3.5e-21 76.0 0.2 2.1e-20 73.4 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR63196.1 - 9.4e-12 46.0 4.8 1.2e-11 45.6 4.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR63196.1 - 3.8e-07 29.6 0.1 1.6e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 EMR63196.1 - 0.018 15.4 0.1 0.076 13.4 0.0 2.0 3 0 0 3 3 3 0 Epoxide hydrolase N terminus DLH PF01738.18 EMR63196.1 - 0.018 14.6 0.1 1.9 8.0 0.1 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family Inj_translocase PF16928.5 EMR63196.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome DUF4360 PF14273.6 EMR63197.1 - 2.1e-34 118.9 0.2 2.4e-34 118.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF945 PF06097.11 EMR63197.1 - 0.17 10.9 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) SH3_9 PF14604.6 EMR63198.1 - 2e-05 24.4 0.2 0.00011 21.9 0.1 2.3 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 EMR63198.1 - 0.0011 18.5 0.2 0.0021 17.7 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMR63198.1 - 0.032 13.8 3.0 0.12 12.0 2.7 2.0 2 0 0 2 2 2 0 SH3 domain Pyr_redox_3 PF13738.6 EMR63199.1 - 3e-16 59.5 0.0 5.3e-14 52.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR63199.1 - 7.5e-16 58.2 0.0 8.4e-13 48.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMR63199.1 - 2.4e-11 42.8 0.2 8.3e-11 41.0 0.1 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMR63199.1 - 4.5e-09 35.9 0.1 2.4e-06 26.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EMR63199.1 - 2.6e-07 30.2 0.0 0.00099 18.4 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 EMR63199.1 - 1.6e-06 28.6 0.1 0.0074 16.8 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR63199.1 - 0.00014 22.1 0.0 0.0054 16.9 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain SnoaL_4 PF13577.6 EMR63199.1 - 0.00023 21.3 0.7 0.0016 18.6 0.7 2.4 1 1 0 1 1 1 1 SnoaL-like domain 2-Hacid_dh_C PF02826.19 EMR63199.1 - 0.0013 18.2 0.1 0.015 14.6 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 EMR63199.1 - 0.0049 16.1 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.12 EMR63199.1 - 0.016 14.2 0.0 0.06 12.4 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR63199.1 - 0.017 14.3 0.0 0.056 12.5 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain DUF928 PF06051.12 EMR63199.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) SnoaL_2 PF12680.7 EMR63199.1 - 0.02 15.6 0.1 0.078 13.6 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain Telomere_reg-2 PF10193.9 EMR63200.1 - 4.4e-36 123.6 0.0 1.2e-35 122.3 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein GP67 PF17634.2 EMR63200.1 - 0.52 10.8 5.9 1.3 9.5 5.9 1.6 1 0 0 1 1 1 0 Gene product 67 Tannase PF07519.11 EMR63201.1 - 1.5e-88 297.8 0.3 1.7e-88 297.6 0.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EMR63201.1 - 0.044 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMR63201.1 - 0.045 13.2 0.0 0.97 8.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family KR PF08659.10 EMR63202.1 - 3.7e-59 199.7 0.0 7.9e-59 198.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EMR63202.1 - 7.6e-43 147.2 0.1 1.4e-42 146.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EMR63202.1 - 2.4e-41 142.0 0.0 2e-32 112.8 0.0 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR63202.1 - 2.2e-34 118.0 0.4 7.2e-34 116.3 0.4 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EMR63202.1 - 4.7e-27 95.0 0.0 8.1e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.25 EMR63202.1 - 1.2e-11 44.4 0.0 6.3e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EMR63202.1 - 6.4e-11 42.7 0.2 2.2e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EMR63202.1 - 7.5e-09 35.6 0.1 3.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EMR63202.1 - 4.7e-05 23.7 0.1 0.00015 22.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 EMR63202.1 - 0.0062 17.6 0.0 0.027 15.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR63202.1 - 0.045 13.2 0.0 0.15 11.5 0.0 2.0 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Esterase_phd PF10503.9 EMR63203.1 - 2.1e-07 30.7 1.0 2.5e-06 27.1 0.1 2.9 2 1 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMR63203.1 - 0.001 18.6 0.1 0.0022 17.5 0.0 1.5 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 EMR63203.1 - 0.0086 14.8 0.0 0.029 13.1 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) G-alpha PF00503.20 EMR63204.1 - 4.1e-49 167.6 0.0 4.6e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EMR63204.1 - 0.0085 15.6 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_29 PF13555.6 EMR63204.1 - 0.045 13.5 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EMR63205.1 - 4.9e-17 62.6 0.0 9.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMR63205.1 - 0.0016 18.7 0.1 0.014 15.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMR63205.1 - 0.012 15.3 0.0 0.042 13.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 EMR63205.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMR63205.1 - 0.042 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 EMR63205.1 - 0.071 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR63205.1 - 0.08 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EMR63205.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps36_ESCRT-II PF11605.8 EMR63205.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Acid_PPase PF12689.7 EMR63206.1 - 2.3e-59 200.0 0.0 4.2e-59 199.2 0.0 1.4 1 0 0 1 1 1 1 Acid Phosphatase Phosphorylase PF00343.20 EMR63207.1 - 0 1042.2 0.0 0 1042.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Fringe PF02434.16 EMR63207.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Fungal_trans PF04082.18 EMR63208.1 - 4.4e-19 68.6 0.6 1.8e-17 63.3 0.2 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain RNA_pol_A_bac PF01000.26 EMR63209.1 - 4.9e-25 88.1 0.0 1.1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EMR63209.1 - 1.1e-20 72.8 0.0 1.5e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RVT_3 PF13456.6 EMR63210.1 - 0.00066 19.5 0.0 0.024 14.5 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like zf-ZPR1 PF03367.13 EMR63211.1 - 4.3e-113 374.4 0.0 5.4e-58 195.4 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-RRPl_C4 PF17026.5 EMR63211.1 - 0.016 15.3 1.6 0.52 10.4 0.2 2.2 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type PAF-AH_p_II PF03403.13 EMR63212.1 - 3.4e-35 121.3 0.0 9.8e-32 109.9 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EMR63212.1 - 1.4e-09 37.3 0.0 4.2e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EMR63212.1 - 8.2e-08 33.1 0.2 2.3e-07 31.6 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR63212.1 - 2.5e-05 23.7 0.1 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMR63212.1 - 0.0018 17.8 0.2 0.21 11.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.11 EMR63212.1 - 0.0064 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.13 EMR63212.1 - 0.017 15.0 0.0 0.05 13.5 0.0 1.8 3 0 0 3 3 3 0 alpha/beta hydrolase fold GLEYA PF10528.9 EMR63214.1 - 3.3e-16 59.5 0.1 7.1e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 GLEYA domain Het-C PF07217.11 EMR63215.1 - 0.089 11.3 0.5 0.11 11.0 0.5 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Baculo_PEP_C PF04513.12 EMR63215.1 - 0.11 12.5 13.6 1 9.4 13.2 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_72 PF03198.14 EMR63216.1 - 7.1e-72 242.3 0.0 2e-71 240.8 0.0 1.6 1 1 0 1 1 1 1 Glucanosyltransferase DUF3398 PF11878.8 EMR63216.1 - 0.065 13.7 0.3 0.49 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) DUF3176 PF11374.8 EMR63217.1 - 0.64 10.2 5.0 1.8 8.8 5.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) Ank_2 PF12796.7 EMR63219.1 - 7.4e-26 90.6 0.0 2.8e-08 34.2 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR63219.1 - 3e-20 72.3 0.3 1.6e-05 25.3 0.0 6.4 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EMR63219.1 - 1.5e-19 69.4 4.4 6.3e-05 23.2 0.1 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EMR63219.1 - 8.2e-18 64.2 0.3 0.00027 21.2 0.0 6.0 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR63219.1 - 2.8e-17 61.0 0.1 0.012 16.0 0.0 7.2 8 0 0 8 8 8 4 Ankyrin repeat VIT1 PF01988.19 EMR63220.1 - 0.0069 16.3 0.4 0.0069 16.3 0.4 2.0 2 0 0 2 2 2 1 VIT family Presenilin PF01080.17 EMR63220.1 - 5 5.8 12.2 7.7 5.2 12.2 1.3 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 EMR63220.1 - 9.5 6.3 9.8 16 5.6 8.8 1.8 2 0 0 2 2 2 0 DDHD domain HeLo PF14479.6 EMR63221.1 - 3.5e-31 108.6 0.8 6.4e-31 107.8 0.8 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 EMR63221.1 - 0.0015 18.0 0.0 0.0046 16.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Frankia_peptide PF14407.6 EMR63221.1 - 0.18 11.8 1.1 0.39 10.7 0.2 1.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. GFO_IDH_MocA PF01408.22 EMR63222.1 - 3.4e-18 66.6 0.0 6.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EMR63222.1 - 0.00012 22.6 0.0 0.00022 21.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.7 EMR63223.1 - 2.1e-67 223.7 1.5 1.1e-13 51.6 0.0 5.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR63223.1 - 2.5e-40 136.0 2.2 2.1e-08 34.3 0.0 6.2 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR63223.1 - 1.5e-39 129.5 0.3 0.005 17.2 0.0 11.4 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.6 EMR63223.1 - 5.8e-39 132.0 1.2 1.7e-07 31.6 0.0 8.0 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EMR63223.1 - 1.1e-34 117.4 13.8 0.00028 21.2 0.1 10.4 10 1 0 10 10 10 7 Ankyrin repeat PIR PF00399.19 EMR63224.1 - 0.00078 18.9 27.6 0.0056 16.2 0.9 4.9 4 0 0 4 4 4 4 Yeast PIR protein repeat Totivirus_coat PF05518.11 EMR63224.1 - 2.1 6.3 13.2 2.7 6.0 13.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein HET PF06985.11 EMR63225.1 - 8.2e-34 117.0 0.1 1.8e-33 116.0 0.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.6 EMR63225.1 - 1.1e-06 28.8 0.0 3.1e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR63225.1 - 2.2e-06 28.1 0.1 1.9e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR63225.1 - 5.2e-06 26.9 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EMR63225.1 - 0.00012 22.3 0.0 0.13 12.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EMR63225.1 - 0.00077 19.7 0.0 0.15 12.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Med15_fungi PF05397.12 EMR63225.1 - 0.0097 16.2 0.7 0.016 15.5 0.1 1.6 2 0 0 2 2 2 1 Mediator complex subunit 15 NAD_binding_10 PF13460.6 EMR63226.1 - 7.2e-21 74.9 0.0 1.3e-20 74.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR63226.1 - 3.6e-09 36.5 0.0 5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR63226.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Bestrophin PF01062.21 EMR63228.1 - 2.7e-28 99.2 0.0 4.4e-28 98.5 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel zf-U1 PF06220.12 EMR63229.1 - 1.8e-06 27.6 0.3 2.9e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 U1 zinc finger Transferase PF02458.15 EMR63230.1 - 3e-12 45.9 0.0 4.3e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family Tyrosinase PF00264.20 EMR63231.1 - 2.1e-31 109.9 0.2 1.3e-30 107.4 0.2 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase adh_short_C2 PF13561.6 EMR63235.1 - 7.2e-55 186.1 2.7 1.1e-54 185.5 2.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR63235.1 - 2.3e-39 134.9 1.1 4.7e-39 133.9 1.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR63235.1 - 3.9e-08 33.4 0.5 1.6e-07 31.4 0.1 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EMR63235.1 - 0.045 12.9 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_11 PF08241.12 EMR63236.1 - 0.00053 20.6 0.0 0.002 18.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR63236.1 - 0.00059 20.5 0.0 0.00093 19.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR63236.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain adh_short PF00106.25 EMR63237.1 - 1.9e-14 53.6 0.0 2.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63237.1 - 8.4e-13 48.4 0.0 2.2e-08 33.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR63237.1 - 0.0029 17.6 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 KR domain STE3 PF02076.15 EMR63238.1 - 1.2e-46 159.3 5.8 5.1e-40 137.5 2.1 2.0 2 0 0 2 2 2 2 Pheromone A receptor Aldo_ket_red PF00248.21 EMR63239.1 - 1.2e-52 179.0 0.0 1.3e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_1 PF00232.18 EMR63240.1 - 6.7e-62 209.4 3.3 5.2e-37 127.3 0.2 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Erf4 PF10256.9 EMR63243.1 - 6.2e-40 135.9 0.0 7.6e-40 135.6 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family MtrG PF04210.13 EMR63243.1 - 0.078 12.8 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Hormone_3 PF00159.18 EMR63244.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide DUF2654 PF10849.8 EMR63244.1 - 4.1 7.7 5.3 14 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) adh_short PF00106.25 EMR63245.1 - 1.5e-39 135.5 0.0 2.3e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63245.1 - 6.9e-31 107.6 0.0 9.4e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR63245.1 - 1.5e-09 38.1 0.0 2.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMR63245.1 - 0.00095 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 EMR63245.1 - 0.013 15.3 0.3 0.032 14.0 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Choline_transpo PF04515.12 EMR63246.1 - 4.1e-25 88.7 14.9 7.7e-25 87.8 14.9 1.4 1 1 0 1 1 1 1 Plasma-membrane choline transporter Cys_Met_Meta_PP PF01053.20 EMR63247.1 - 8.4e-147 488.7 0.0 9.5e-147 488.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMR63247.1 - 1.9e-10 40.3 0.2 3.1e-09 36.3 0.2 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMR63247.1 - 1.4e-09 37.7 0.0 2.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMR63247.1 - 4e-09 36.3 0.2 8e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EMR63247.1 - 8.9e-08 31.8 0.0 2.2e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EMR63247.1 - 0.00012 20.8 0.0 0.00018 20.2 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Ribosomal_60s PF00428.19 EMR63247.1 - 0.043 14.4 5.4 0.064 13.9 0.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein SepSecS PF05889.13 EMR63247.1 - 0.061 12.0 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Asparaginase_C PF17763.1 EMR63247.1 - 0.064 13.5 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain MccV PF17508.2 EMR63247.1 - 6.5 7.4 8.0 0.36 11.4 0.6 2.6 3 0 0 3 3 3 0 Microcin V bacteriocin MARVEL PF01284.23 EMR63248.1 - 6.5e-14 52.2 16.3 8.1e-14 51.9 16.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Ribosomal_L27e PF01777.18 EMR63249.1 - 5.4e-37 126.0 2.9 8.1e-37 125.4 2.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EMR63249.1 - 0.0074 16.2 0.9 0.018 15.0 0.9 1.7 1 0 0 1 1 1 1 KOW motif Glyoxalase PF00903.25 EMR63250.1 - 2.9e-19 69.5 0.1 2.4e-12 47.1 0.0 2.8 2 1 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMR63250.1 - 6.9e-14 52.1 0.1 4e-06 27.0 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EMR63250.1 - 1e-05 25.7 0.4 0.43 10.7 0.0 3.2 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EMR63250.1 - 0.0082 16.3 0.1 0.034 14.3 0.1 1.9 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_6 PF18029.1 EMR63250.1 - 0.024 15.4 0.2 3.7 8.4 0.3 2.7 2 2 0 2 2 2 0 Glyoxalase-like domain WW PF00397.26 EMR63251.1 - 0.0033 17.5 0.6 0.0064 16.6 0.6 1.5 1 0 0 1 1 1 1 WW domain CYSTM PF12734.7 EMR63251.1 - 0.58 10.5 0.1 0.58 10.5 0.1 4.8 4 1 0 4 4 4 0 Cysteine-rich TM module stress tolerance Sugar_tr PF00083.24 EMR63252.1 - 4.4e-66 223.6 7.9 4.8e-65 220.2 6.3 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR63252.1 - 7.5e-24 84.3 7.8 9.6e-24 84.0 7.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EMR63252.1 - 2.3e-06 26.4 4.2 2.3e-06 26.4 4.2 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_5 PF05631.14 EMR63252.1 - 8.4e-05 21.6 1.0 0.00013 21.0 1.0 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF2530 PF10745.9 EMR63252.1 - 0.39 11.0 2.3 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) FAD_binding_3 PF01494.19 EMR63253.1 - 1.2e-22 80.6 2.9 6e-15 55.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EMR63253.1 - 2.8e-07 30.1 0.2 1.4e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR63253.1 - 6.2e-05 22.4 3.8 0.0094 15.2 0.4 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR63253.1 - 0.0003 21.0 0.2 0.00098 19.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EMR63253.1 - 0.0043 16.0 0.2 0.02 13.7 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EMR63253.1 - 0.0054 15.8 0.7 0.018 14.1 0.7 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR63253.1 - 0.039 13.0 1.4 0.067 12.3 1.4 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EMR63253.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EMR63253.1 - 0.1 11.8 0.6 0.21 10.8 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EMR63253.1 - 0.16 12.6 0.4 0.16 12.6 0.4 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR63253.1 - 0.2 10.3 0.5 0.31 9.7 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 EMR63253.1 - 0.26 10.8 2.5 0.19 11.3 0.3 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase TPT PF03151.16 EMR63254.1 - 1.6e-27 96.6 24.8 1.9e-27 96.3 24.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Ssl1 PF04056.14 EMR63255.1 - 3.1e-70 235.9 0.0 9.7e-70 234.3 0.0 1.7 1 1 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EMR63255.1 - 1.2e-17 63.9 1.2 1.2e-17 63.9 1.2 3.8 4 0 0 4 4 4 1 TFIIH C1-like domain VWA_2 PF13519.6 EMR63255.1 - 2e-15 57.4 0.0 4.6e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 EMR63255.1 - 0.21 11.0 3.8 0.58 9.6 3.8 1.7 1 0 0 1 1 1 0 Transcription factor Tfb4 TPR_17 PF13431.6 EMR63256.1 - 0.088 13.2 0.0 0.82 10.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_Tnp_Tc3_1 PF11427.8 EMR63256.1 - 0.091 12.6 0.5 1.2 9.0 0.0 2.7 2 1 1 3 3 3 0 Tc3 transposase Chs7 PF12271.8 EMR63257.1 - 1.6e-100 336.2 5.3 2.1e-100 335.8 5.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Herpes_UL20 PF04544.12 EMR63257.1 - 0.032 14.6 4.7 0.063 13.6 0.4 2.8 2 2 2 4 4 4 0 Herpesvirus egress protein UL20 Ery_res_leader1 PF08051.11 EMR63257.1 - 0.32 11.2 1.1 11 6.5 0.1 3.3 2 1 0 2 2 2 0 Erythromycin resistance leader peptide FixQ PF05545.11 EMR63257.1 - 4.1 7.4 6.2 15 5.6 0.0 3.6 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1218 PF06749.12 EMR63257.1 - 8.8 6.9 10.1 10 6.7 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Ras PF00071.22 EMR63258.1 - 1.5e-47 161.2 0.0 4e-36 124.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EMR63258.1 - 9.3e-28 96.9 0.0 3.5e-17 62.7 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR63258.1 - 4.1e-08 32.9 0.0 1.5e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMR63258.1 - 4.6e-07 29.6 0.2 2e-06 27.5 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMR63258.1 - 1.5e-05 24.5 0.0 3.7e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMR63258.1 - 0.00066 19.7 0.1 0.009 16.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR63258.1 - 0.07 13.0 0.2 0.9 9.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EMR63258.1 - 0.2 11.9 0.1 0.41 10.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Secretin_N_2 PF07655.13 EMR63258.1 - 1.1 9.8 8.2 1 9.9 2.1 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Menin PF05053.13 EMR63258.1 - 3.3 6.0 7.5 3.1 6.0 0.5 2.0 2 0 0 2 2 2 0 Menin DUF2012 PF09430.10 EMR63259.1 - 6.7e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) PMT PF02366.18 EMR63260.1 - 1.3e-81 273.9 16.8 1.3e-81 273.9 16.8 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMR63260.1 - 5.1e-66 222.1 14.5 5.1e-66 222.1 14.5 2.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMR63260.1 - 2.4e-37 128.6 0.5 3.8e-37 128.0 0.5 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 EMR63260.1 - 0.15 11.9 1.8 1.5 8.6 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DAO PF01266.24 EMR63261.1 - 7e-22 78.5 0.0 3.1e-20 73.1 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HSDR_N_2 PF13588.6 EMR63261.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Glyco_hydro_76 PF03663.14 EMR63262.1 - 2.3e-116 389.3 2.1 2.9e-116 389.0 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Phage_r1t_holin PF16945.5 EMR63262.1 - 4.7 7.5 7.9 0.37 11.0 1.5 2.5 3 0 0 3 3 3 0 Putative lactococcus lactis phage r1t holin Fungal_trans PF04082.18 EMR63263.1 - 1.2e-11 44.2 0.0 2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR63263.1 - 1.8e-07 31.2 7.6 3.7e-07 30.2 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.12 EMR63263.1 - 0.065 13.2 3.4 0.12 12.3 1.4 2.1 2 0 0 2 2 2 0 Serglycin CENP-Q PF13094.6 EMR63264.1 - 0.069 13.4 0.1 0.083 13.1 0.1 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NACHT PF05729.12 EMR63265.1 - 5.5e-10 39.4 0.0 1.7e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 EMR63265.1 - 2.2e-09 37.7 0.1 0.0039 17.7 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR63265.1 - 2.5e-09 36.6 0.1 1.1 10.1 0.0 6.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 EMR63265.1 - 3.6e-09 37.1 0.0 3.9e-05 24.2 0.1 3.6 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) AAA_22 PF13401.6 EMR63265.1 - 2.8e-07 30.9 0.1 1.4e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMR63265.1 - 1.9e-06 28.4 0.0 4.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Ank_5 PF13857.6 EMR63265.1 - 0.00012 22.3 0.3 0.47 10.8 0.2 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) TrwB_AAD_bind PF10412.9 EMR63265.1 - 0.0014 17.6 0.0 0.11 11.4 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 EMR63265.1 - 0.0061 16.6 0.0 0.022 14.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 EMR63265.1 - 0.0077 16.2 0.1 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 EMR63265.1 - 0.016 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain DAP3 PF10236.9 EMR63265.1 - 0.12 11.5 0.0 0.64 9.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 KAP_NTPase PF07693.14 EMR63265.1 - 0.15 11.2 0.0 0.37 10.0 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Aldo_ket_red PF00248.21 EMR63266.1 - 1.8e-26 93.0 0.0 2.1e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.29 EMR63267.1 - 1.8e-20 73.7 0.0 4.7e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR63267.1 - 5.5e-05 23.6 2.5 0.00032 21.1 0.3 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EMR63267.1 - 0.00014 22.1 0.0 0.00048 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMR63267.1 - 0.00042 20.6 0.4 0.012 15.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 EMR63267.1 - 0.0012 18.8 0.0 0.0054 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EMR63267.1 - 0.0023 18.0 0.0 0.029 14.4 0.0 2.6 1 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EMR63267.1 - 0.0067 16.2 0.2 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EMR63267.1 - 0.017 14.8 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EMR63267.1 - 0.032 13.8 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMR63267.1 - 0.038 14.2 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EMR63267.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Torsin PF06309.11 EMR63267.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin Zip PF02535.22 EMR63267.1 - 0.51 9.5 2.3 0.86 8.7 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_11 PF13086.6 EMR63267.1 - 0.8 9.4 9.3 1 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain hNIFK_binding PF12196.8 EMR63267.1 - 1.2 8.7 5.4 3 7.4 0.5 3.4 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK Striatin PF08232.12 EMR63267.1 - 2.1 8.9 16.2 0.51 10.9 12.2 2.0 2 0 0 2 2 2 0 Striatin family RXT2_N PF08595.11 EMR63267.1 - 2.8 7.9 12.1 11 6.0 0.1 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Cyt-b5 PF00173.28 EMR63269.1 - 6.9e-17 61.4 1.3 1.4e-16 60.4 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EMR63269.1 - 1.8e-12 47.8 22.0 1.8e-12 47.8 22.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EMR63269.1 - 0.0049 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region DUF1996 PF09362.10 EMR63270.1 - 1.6e-84 283.5 2.1 2e-84 283.3 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AAA PF00004.29 EMR63271.1 - 1.8e-36 125.4 0.0 4.9e-36 124.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SGT1 PF07093.11 EMR63271.1 - 7.3e-32 110.6 28.3 1.2e-21 76.8 0.3 3.3 2 1 0 3 3 3 3 SGT1 protein Vps4_C PF09336.10 EMR63271.1 - 2.7e-08 33.7 0.0 6.1e-07 29.3 0.0 3.1 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EMR63271.1 - 5.4e-08 32.5 0.1 2.1e-07 30.6 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EMR63271.1 - 5.2e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR63271.1 - 0.0001 22.6 0.4 0.0028 18.0 0.0 3.0 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 EMR63271.1 - 0.00058 20.3 2.2 0.0035 17.7 0.1 3.1 3 1 0 3 3 2 1 AAA ATPase domain TIP49 PF06068.13 EMR63271.1 - 0.0011 18.2 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EMR63271.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EMR63271.1 - 0.0056 16.7 0.0 0.017 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMR63271.1 - 0.0064 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Ndc1_Nup PF09531.10 EMR63271.1 - 0.011 14.5 0.5 0.018 13.8 0.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AAA_24 PF13479.6 EMR63271.1 - 0.012 15.4 0.1 0.13 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EMR63271.1 - 0.016 14.4 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EMR63271.1 - 0.036 14.6 0.2 0.28 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMR63271.1 - 0.037 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMR63271.1 - 0.047 13.3 0.2 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 EMR63271.1 - 0.06 12.8 0.2 7 6.1 0.0 3.1 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EMR63271.1 - 0.061 13.4 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMR63271.1 - 0.23 10.9 0.0 0.5 9.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EMR63271.1 - 2 8.1 0.0 2 8.1 0.0 3.6 3 2 0 3 3 3 0 AAA domain SMC_N PF02463.19 EMR63272.1 - 3.6e-21 75.6 14.8 4.6e-10 39.3 0.1 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMR63272.1 - 1.4e-16 61.6 14.6 1.4e-16 61.6 14.6 5.2 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 EMR63272.1 - 3e-16 60.1 0.3 3e-16 60.1 0.3 3.2 2 2 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 EMR63272.1 - 9.3e-07 28.9 1.6 0.00058 19.8 0.2 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMR63272.1 - 0.00082 19.1 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EMR63272.1 - 0.0014 18.8 0.0 0.004 17.3 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF812 PF05667.11 EMR63272.1 - 0.0035 16.3 15.2 0.0035 16.3 15.2 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF812) SMC_hinge PF06470.13 EMR63272.1 - 0.033 14.5 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain Mga PF05043.13 EMR63272.1 - 0.1 13.2 1.7 7.6 7.2 0.1 3.1 2 0 0 2 2 2 0 Mga helix-turn-helix domain Pox_A_type_inc PF04508.12 EMR63272.1 - 0.79 9.7 7.1 6.4 6.8 0.1 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat EKAL PF17986.1 EMR63272.1 - 3.2 7.8 4.8 0.9 9.6 0.2 2.5 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain EthD PF07110.11 EMR63273.1 - 3.3e-09 37.8 0.0 4e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 EthD domain Pirin PF02678.16 EMR63274.1 - 1.8e-17 63.3 3.1 3.6e-16 59.1 3.1 2.5 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EMR63274.1 - 0.026 14.2 0.9 6 6.7 0.0 3.0 3 0 0 3 3 3 0 Cupin domain AraC_binding_2 PF14525.6 EMR63274.1 - 0.043 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 AraC-binding-like domain Glyco_hydro_18 PF00704.28 EMR63275.1 - 3.7e-18 66.3 0.1 7.5e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hormone_4 PF00220.17 EMR63275.1 - 0.05 13.5 1.0 23 5.3 0.1 3.3 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain Macoilin PF09726.9 EMR63275.1 - 7.3 5.0 14.0 11 4.4 14.0 1.2 1 0 0 1 1 1 0 Macoilin family PEP-utilisers_N PF05524.13 EMR63276.1 - 0.025 14.7 0.2 0.075 13.2 0.2 1.8 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal RNase_PH PF01138.21 EMR63278.1 - 8e-35 120.2 0.5 1.2e-34 119.6 0.5 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ADH_N PF08240.12 EMR63279.1 - 6.6e-27 93.6 2.1 1.4e-26 92.5 2.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR63279.1 - 2.7e-18 66.2 0.0 4.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR63279.1 - 6.7e-05 24.0 0.0 0.00012 23.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EMR63279.1 - 0.0014 18.4 0.5 0.0022 17.8 0.5 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase POR PF01558.18 EMR63279.1 - 0.0034 17.5 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase 2-Hacid_dh_C PF02826.19 EMR63279.1 - 0.014 14.7 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR63279.1 - 0.015 14.6 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.19 EMR63279.1 - 0.053 12.2 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase CoA_binding PF02629.19 EMR63279.1 - 0.071 13.8 0.3 0.2 12.3 0.2 1.8 2 0 0 2 2 2 0 CoA binding domain NIF PF03031.18 EMR63281.1 - 8.2e-40 136.1 0.0 1.2e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Motilin_assoc PF04643.12 EMR63281.1 - 0.1 12.5 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide adh_short_C2 PF13561.6 EMR63282.1 - 2.8e-56 190.7 0.6 3.7e-56 190.3 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR63282.1 - 1.4e-48 164.9 1.5 1.7e-48 164.6 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR63282.1 - 7e-11 42.4 0.5 1.5e-10 41.3 0.3 1.6 1 1 0 2 2 2 1 KR domain Epimerase PF01370.21 EMR63282.1 - 0.00012 21.6 0.1 0.00023 20.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMR63282.1 - 0.0039 16.4 0.2 0.0053 15.9 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMR63282.1 - 0.015 14.4 0.1 0.03 13.4 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4854 PF16146.5 EMR63282.1 - 0.1 12.9 0.0 1.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Vta1 PF04652.16 EMR63283.1 - 2.9e-56 189.5 0.7 3.6e-56 189.2 0.7 1.1 1 0 0 1 1 1 1 Vta1 like Atx10homo_assoc PF09759.9 EMR63283.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Thioredoxin PF00085.20 EMR63284.1 - 3.9e-32 110.3 0.1 9.2e-25 86.6 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 EMR63284.1 - 1.9e-06 28.2 0.8 0.0041 17.5 0.8 2.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 EMR63284.1 - 4.4e-06 26.7 0.0 0.0031 17.4 0.0 3.1 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EMR63284.1 - 1.4e-05 24.6 0.0 0.00027 20.4 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EMR63284.1 - 0.00033 20.9 0.1 3.4 8.1 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like QSOX_Trx1 PF18108.1 EMR63284.1 - 0.0036 17.5 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 QSOX Trx-like domain ERp29_N PF07912.13 EMR63284.1 - 0.004 17.3 0.1 0.11 12.6 0.0 2.6 2 1 0 2 2 2 1 ERp29, N-terminal domain AhpC-TSA PF00578.21 EMR63284.1 - 0.011 15.6 0.1 0.05 13.5 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family TraF PF13728.6 EMR63284.1 - 0.026 14.3 0.0 0.026 14.3 0.0 3.6 3 1 1 4 4 4 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EMR63284.1 - 0.035 14.3 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Glyco_hydro_61 PF03443.14 EMR63285.1 - 1.2e-25 90.7 0.0 1e-24 87.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.25 EMR63286.1 - 4.9e-52 176.9 0.0 6.5e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR63286.1 - 3.5e-25 88.8 0.0 5e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR63286.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMR63286.1 - 0.017 14.5 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR63286.1 - 0.045 13.7 0.0 0.42 10.5 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMR63286.1 - 0.18 10.6 0.0 0.63 8.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase PIP49_C PF12260.8 EMR63286.1 - 0.18 11.4 0.0 0.47 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 RGS PF00615.19 EMR63287.1 - 1.5e-12 47.9 0.0 3.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain GST_C_2 PF13410.6 EMR63289.1 - 2e-08 34.2 0.4 3.4e-08 33.4 0.4 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR63289.1 - 0.015 15.5 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMR63289.1 - 0.045 14.3 0.3 0.15 12.7 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR63289.1 - 0.099 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1793 PF08760.11 EMR63289.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) FAD_binding_3 PF01494.19 EMR63290.1 - 2.6e-18 66.4 0.4 2.2e-14 53.4 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMR63290.1 - 8.8e-05 22.7 0.2 0.00039 20.6 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMR63290.1 - 0.00025 21.1 1.1 0.031 14.2 0.1 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMR63290.1 - 0.0018 17.6 0.2 0.0032 16.7 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR63290.1 - 0.0097 15.0 0.0 0.7 8.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 EMR63290.1 - 0.017 15.6 0.0 0.063 13.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EMR63290.1 - 0.029 13.4 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 EMR63290.1 - 0.035 13.7 0.2 0.065 12.8 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_25 PF13649.6 EMR63291.1 - 5.6e-17 62.2 0.0 1.2e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR63291.1 - 1.4e-15 57.7 0.0 2.6e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR63291.1 - 1e-11 45.0 0.0 1.4e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR63291.1 - 3.6e-10 39.8 0.0 4.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR63291.1 - 2.5e-09 37.8 0.0 4.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EMR63291.1 - 0.00029 20.6 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EMR63291.1 - 0.00054 19.5 0.0 0.00086 18.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EMR63291.1 - 0.00069 19.0 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EMR63291.1 - 0.0049 16.2 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMR63291.1 - 0.0091 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ank_4 PF13637.6 EMR63292.1 - 2e-12 47.3 0.0 4.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR63292.1 - 4e-10 40.1 0.0 2e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR63292.1 - 1.5e-09 37.9 1.1 1.2e-05 25.5 0.1 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR63292.1 - 2.6e-09 36.6 0.3 0.0015 18.8 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EMR63292.1 - 0.00021 21.6 4.5 0.08 13.4 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat PikAIV_N PF18605.1 EMR63292.1 - 0.19 11.4 0.9 0.35 10.5 0.9 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Atg14 PF10186.9 EMR63293.1 - 1.5e-14 53.8 8.5 2.5e-12 46.5 8.5 2.7 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EMR63293.1 - 8.5e-10 38.1 0.0 2.6e-05 23.3 0.0 3.2 3 0 0 3 3 3 3 Vacuolar protein sorting 38 TauD PF02668.16 EMR63294.1 - 3.2e-45 155.0 0.1 5.2e-45 154.3 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.32 EMR63294.1 - 1.8e-08 34.9 6.0 0.0051 17.6 0.3 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR63294.1 - 0.00014 22.1 0.1 0.17 12.2 0.1 3.4 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ax_dynein_light PF10211.9 EMR63294.1 - 0.074 13.0 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Plasmod_MYXSPDY PF07981.11 EMR63294.1 - 0.18 11.8 0.1 0.42 10.6 0.1 1.6 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Glyco_hydro_18 PF00704.28 EMR63295.1 - 3.4e-21 76.3 1.6 9.4e-21 74.8 1.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 EMR63295.1 - 6.3e-08 32.4 13.7 1.9e-07 30.9 13.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain SMC_N PF02463.19 EMR63296.1 - 1.8e-07 30.9 0.0 1.2e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 EMR63296.1 - 0.00011 22.7 0.2 0.32 11.5 0.0 2.9 1 1 0 2 2 2 2 ABC transporter SbcCD_C PF13558.6 EMR63296.1 - 0.006 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.23 EMR63296.1 - 0.077 12.6 0.0 0.077 12.6 0.0 2.4 2 1 1 3 3 3 0 ABC transporter transmembrane region Myb_DNA-bind_3 PF12776.7 EMR63297.1 - 0.0064 17.5 0.0 0.011 16.7 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain AadA_C PF18280.1 EMR63297.1 - 0.029 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside adenyltransferase C-terminal domain DUF573 PF04504.14 EMR63297.1 - 0.067 13.9 0.0 0.12 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF573 RNA_pol_Rpc4 PF05132.14 EMR63297.1 - 4 7.9 7.5 0.65 10.4 3.6 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 SET PF00856.28 EMR63298.1 - 9.9e-16 58.6 0.0 5.3e-15 56.2 0.0 1.9 1 1 0 1 1 1 1 SET domain UQ_con PF00179.26 EMR63299.1 - 4.6e-47 159.2 0.0 5.7e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMR63299.1 - 9.5e-05 22.1 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMR63299.1 - 0.001 19.3 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EMR63299.1 - 0.007 16.2 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain MFS_1 PF07690.16 EMR63300.1 - 7.1e-29 100.8 29.1 7.1e-29 100.8 29.1 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily PepSY_TM_like_2 PF16357.5 EMR63300.1 - 0.074 13.0 1.1 0.14 12.1 1.1 1.4 1 0 0 1 1 1 0 Putative PepSY_TM-like Colicin_E5 PF12106.8 EMR63301.1 - 0.018 15.3 0.5 0.14 12.5 0.5 2.5 1 0 0 1 1 1 0 Colicin E5 ribonuclease domain hNIFK_binding PF12196.8 EMR63301.1 - 2.4 7.7 7.9 15 5.1 0.0 4.4 4 0 0 4 4 4 0 FHA Ki67 binding domain of hNIFK Glyco_hydro_79C PF16862.5 EMR63302.1 - 5.3e-23 81.9 0.3 1.1e-22 80.8 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Flagellin_C PF00700.21 EMR63304.1 - 0.011 16.1 0.4 2.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region SesA PF17107.5 EMR63304.1 - 0.023 14.9 0.5 0.031 14.5 0.5 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 EMR63304.1 - 0.041 14.4 1.8 8.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EMR63304.1 - 0.052 13.8 1.3 1 9.7 0.1 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Helo_like_N PF17111.5 EMR63304.1 - 0.064 12.6 2.4 0.13 11.7 0.5 2.0 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins P22_AR_C PF10548.9 EMR63304.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 P22AR C-terminal domain TFIIB_C_1 PF18542.1 EMR63304.1 - 0.12 12.5 1.5 0.86 9.7 0.1 2.3 2 1 0 2 2 2 0 Transcription factor IIB C-terminal module 1 Tet_JBP PF12851.7 EMR63305.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Glyco_hydro_115 PF15979.5 EMR63308.1 - 1.8e-140 468.2 0.7 2.7e-140 467.7 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EMR63308.1 - 1.5e-44 151.9 0.0 2.8e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Methyltransf_2 PF00891.18 EMR63309.1 - 8.5e-25 87.3 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EMR63309.1 - 5.2e-07 30.3 0.0 1e-06 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR63309.1 - 1.5e-05 25.6 0.0 2.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR63309.1 - 2.3e-05 24.3 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR63309.1 - 0.00085 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EMR63309.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 EMR63309.1 - 0.0027 17.2 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Sigma70_r4 PF04545.16 EMR63309.1 - 0.0049 16.4 0.1 0.0098 15.4 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Methyltransf_18 PF12847.7 EMR63309.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF5427 PF10310.9 EMR63310.1 - 2.1e-182 607.3 0.2 5.6e-182 605.9 0.2 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 EMR63310.1 - 0.024 14.8 0.1 0.066 13.4 0.1 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 EMR63310.1 - 0.25 10.9 6.9 2.4 7.7 4.5 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis NOA36 PF06524.12 EMR63310.1 - 7.8 5.7 6.0 16 4.7 6.0 1.4 1 0 0 1 1 1 0 NOA36 protein CSN7a_helixI PF18392.1 EMR63312.1 - 0.22 11.5 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain NUDIX PF00293.28 EMR63313.1 - 4.6e-05 23.5 0.0 0.00017 21.6 0.0 2.2 2 1 0 2 2 2 1 NUDIX domain CDH-cyt PF16010.5 EMR63314.1 - 1e-54 185.0 1.1 1.5e-54 184.4 0.3 1.7 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EMR63314.1 - 1e-24 87.4 0.0 5.9e-24 85.0 0.0 2.2 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR63314.1 - 5.4e-18 65.9 0.1 1.2e-17 64.8 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR63314.1 - 5.8e-05 22.3 0.5 0.00012 21.3 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EMR63314.1 - 0.00011 21.6 0.6 0.00017 21.0 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR63314.1 - 0.00012 21.4 0.2 0.00067 19.0 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR63314.1 - 0.0002 20.2 1.5 0.00022 20.1 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EMR63314.1 - 0.00044 20.4 0.6 0.0012 19.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR63314.1 - 0.0021 17.1 0.1 0.0036 16.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EMR63314.1 - 0.0045 16.4 1.8 0.0073 15.7 1.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR63314.1 - 0.0074 15.5 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EMR63314.1 - 0.021 14.1 2.2 0.037 13.3 1.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMR63314.1 - 0.033 13.3 0.5 0.052 12.6 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribosomal_L14 PF00238.19 EMR63316.1 - 2.9e-33 114.5 0.0 3.5e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SPT_ssu-like PF11779.8 EMR63317.1 - 2.2e-12 46.4 1.8 3.2e-12 45.9 1.8 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like CbtB PF09489.10 EMR63317.1 - 0.068 13.3 1.6 0.081 13.1 0.6 1.6 1 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) UPRTase PF14681.6 EMR63319.1 - 8.2e-37 126.7 0.1 1.5e-36 125.8 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 EMR63319.1 - 1.3e-18 67.7 0.0 2.5e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain HAD PF12710.7 EMR63319.1 - 1.6e-14 54.7 0.1 3.1e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.27 EMR63319.1 - 0.00068 19.2 0.1 0.0057 16.2 0.1 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain KAP_NTPase PF07693.14 EMR63319.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain MeaB PF03308.16 EMR63319.1 - 0.018 14.0 0.0 0.045 12.7 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EMR63319.1 - 0.037 14.6 0.0 0.15 12.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain Hydrolase_3 PF08282.12 EMR63319.1 - 0.09 12.5 0.0 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NB-ARC PF00931.22 EMR63319.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 EMR63319.1 - 0.13 12.7 0.1 1.4 9.4 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NeuB PF03102.14 EMR63319.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 NeuB family Kinesin PF00225.23 EMR63320.1 - 3.9e-116 387.6 0.0 5.9e-116 387.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMR63320.1 - 2.4e-27 95.7 0.0 5.3e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 EMR63320.1 - 0.051 13.8 7.1 0.037 14.3 5.0 1.9 1 1 0 1 1 1 0 Herpesvirus UL14-like protein zf-C2H2_4 PF13894.6 EMR63321.1 - 9.4e-08 32.3 2.7 0.0028 18.3 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EMR63321.1 - 6.5e-07 29.5 3.1 0.0026 18.1 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EMR63321.1 - 0.032 14.2 1.7 0.34 11.0 0.5 2.2 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EMR63321.1 - 0.17 11.6 0.7 0.32 10.8 0.7 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type Ima1_N PF09779.9 EMR63321.1 - 0.23 12.3 1.9 0.22 12.4 0.3 1.8 2 1 0 2 2 2 0 Ima1 N-terminal domain zf-C2H2_2 PF12756.7 EMR63321.1 - 1.1 9.6 3.9 2.5 8.5 0.4 2.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DEAD PF00270.29 EMR63323.1 - 3.6e-42 144.1 0.0 3.5e-41 140.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR63323.1 - 1.7e-19 70.2 0.0 2.7e-18 66.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR63323.1 - 3e-07 30.6 0.0 4.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMR63323.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EMR63323.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase Ceramidase PF05875.12 EMR63324.1 - 2.1e-58 197.8 0.0 2.7e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Ceramidase WSC PF01822.19 EMR63325.1 - 1.8e-13 50.4 8.9 4.3e-13 49.2 8.9 1.7 1 0 0 1 1 1 1 WSC domain Abhydrolase_5 PF12695.7 EMR63325.1 - 0.002 17.9 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EMR63325.1 - 0.022 15.4 3.9 0.019 15.6 2.6 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_10 PF13460.6 EMR63326.1 - 1.5e-10 41.3 0.2 2.7e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR63326.1 - 3.3e-10 39.9 0.0 4.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR63326.1 - 0.00014 21.4 0.2 0.0002 20.9 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMR63326.1 - 0.00051 20.3 0.1 0.00094 19.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EMR63326.1 - 0.0012 18.9 0.1 0.0027 17.8 0.1 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 EMR63326.1 - 0.012 15.5 0.2 0.018 14.9 0.2 1.2 1 0 0 1 1 1 0 KR domain F420_oxidored PF03807.17 EMR63326.1 - 0.025 15.1 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 EMR63326.1 - 0.041 14.0 0.6 0.065 13.3 0.6 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMR63326.1 - 0.049 12.6 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 EMR63326.1 - 0.086 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 EMR63326.1 - 0.092 13.2 0.2 0.18 12.3 0.2 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EMR63326.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Malic_M PF03949.15 EMR63327.1 - 2.4e-90 302.3 0.1 3e-90 302.0 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EMR63327.1 - 2.9e-61 206.5 0.0 5.1e-61 205.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4692 PF15763.5 EMR63328.1 - 0.48 10.9 7.0 0.96 9.9 7.0 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SR-25 PF10500.9 EMR63328.1 - 0.53 9.8 8.1 0.76 9.3 8.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 EMR63328.1 - 0.77 8.0 6.9 1.1 7.5 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EMR63328.1 - 0.87 7.7 9.8 1.4 7.0 9.8 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EMR63328.1 - 1.2 7.1 16.5 1.7 6.6 16.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 EMR63328.1 - 2.2 7.6 9.1 3.7 6.9 9.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 EMR63328.1 - 2.2 7.5 11.6 3 7.1 11.6 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EMR63328.1 - 2.3 7.6 11.2 3 7.2 11.2 1.1 1 0 0 1 1 1 0 SDA1 AF-4 PF05110.13 EMR63328.1 - 4 5.4 12.3 4.8 5.2 12.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sigma70_ner PF04546.13 EMR63328.1 - 4.9 7.0 6.2 8.7 6.2 6.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region TauD PF02668.16 EMR63329.1 - 2.1e-14 54.0 1.6 3.9e-14 53.1 1.6 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EMR63329.1 - 0.0078 16.8 0.0 0.043 14.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF971) Pkinase PF00069.25 EMR63330.1 - 2.2e-67 227.2 0.0 5.3e-67 226.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR63330.1 - 2e-31 109.2 0.0 5.5e-30 104.5 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR63330.1 - 0.00038 19.9 0.1 0.23 10.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EMR63330.1 - 0.0038 16.1 0.6 0.015 14.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EMR63330.1 - 0.09 12.7 0.0 0.44 10.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family PRP38_assoc PF12871.7 EMR63330.1 - 0.91 10.2 10.8 0.32 11.6 7.4 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RMI1_N PF08585.12 EMR63330.1 - 1.7 8.4 6.0 8.5 6.1 6.0 2.1 1 1 0 1 1 1 0 RecQ mediated genome instability protein JAB PF01398.21 EMR63331.1 - 9.4e-33 112.7 0.0 1.7e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EMR63331.1 - 3.8e-11 43.4 0.4 7.9e-11 42.4 0.4 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EMR63331.1 - 3.9e-07 29.9 0.0 7.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pectate_lyase_2 PF06917.12 EMR63331.1 - 0.14 10.8 0.2 0.57 8.7 0.1 1.9 2 1 1 3 3 3 0 Periplasmic pectate lyase Hist_deacetyl PF00850.19 EMR63332.1 - 1.1e-82 278.0 0.2 2.2e-82 277.0 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Eclosion PF04736.12 EMR63333.1 - 0.17 11.6 1.8 1.8 8.3 0.0 2.9 3 0 0 3 3 3 0 Eclosion hormone Ribosomal_L31e PF01198.19 EMR63334.1 - 2.2e-42 143.1 0.9 3.9e-42 142.4 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 EMR63334.1 - 0.062 13.3 0.1 0.073 13.1 0.1 1.1 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein M20_dimer PF07687.14 EMR63334.1 - 0.073 13.0 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Peptidase dimerisation domain DUF4188 PF13826.6 EMR63335.1 - 3.3e-32 111.3 0.0 4.8e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EMR63335.1 - 0.012 15.0 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase DHDPS PF00701.22 EMR63337.1 - 2.7e-40 137.9 0.0 3.1e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF5023 PF16426.5 EMR63338.1 - 0.19 11.4 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5023) GRDP-like PF07173.12 EMR63339.1 - 6e-09 36.7 2.7 6.8e-09 36.5 0.2 2.0 2 0 0 2 2 2 1 Glycine-rich domain-containing protein-like DUF1045 PF06299.12 EMR63339.1 - 0.082 12.9 0.8 0.16 11.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) ImpA_N PF06812.12 EMR63339.1 - 0.12 12.5 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system Peptidase_S10 PF00450.22 EMR63340.1 - 2e-78 264.7 0.4 3e-78 264.1 0.4 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Attacin_N PF03768.15 EMR63340.1 - 0.15 12.2 0.2 0.53 10.4 0.2 1.9 1 0 0 1 1 1 0 Attacin, N-terminal region DUF2828 PF11443.8 EMR63341.1 - 2e-239 795.9 0.0 4.2e-238 791.6 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) DUF3073 PF11273.8 EMR63341.1 - 8.9 7.1 7.3 46 4.9 7.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) Glyco_hydro_28 PF00295.17 EMR63343.1 - 1.2e-39 136.3 9.3 1.6e-39 135.9 9.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EMR63343.1 - 0.0039 17.0 9.5 0.0039 17.0 9.5 2.6 1 1 1 2 2 2 2 Right handed beta helix region SLT PF01464.20 EMR63344.1 - 0.092 12.4 1.1 0.33 10.6 1.1 1.9 1 1 0 1 1 1 0 Transglycosylase SLT domain Lysozyme_like PF13702.6 EMR63344.1 - 0.14 11.9 1.1 0.55 9.9 1.1 1.9 1 1 0 1 1 1 0 Lysozyme-like APH PF01636.23 EMR63345.1 - 2.1e-07 31.2 0.0 6.2e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMR63345.1 - 0.00034 20.3 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase GTP_cyclohydroI PF01227.22 EMR63346.1 - 1.5e-72 242.8 0.2 1.5e-72 242.8 0.2 1.4 2 0 0 2 2 2 1 GTP cyclohydrolase I QueF PF14489.6 EMR63346.1 - 0.00088 19.4 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein Med19 PF10278.9 EMR63346.1 - 2.6 7.9 10.1 4.5 7.2 10.1 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 LysM PF01476.20 EMR63347.1 - 1.8e-10 40.7 0.0 0.00082 19.4 0.0 3.2 3 0 0 3 3 3 2 LysM domain Glyco_hydro_18 PF00704.28 EMR63348.1 - 5e-36 125.0 0.1 7.9e-36 124.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TAFII28 PF04719.14 EMR63349.1 - 9.6e-30 102.5 0.2 2e-29 101.5 0.2 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region tRNA-synt_2c PF01411.19 EMR63350.1 - 4e-212 705.6 0.0 4e-212 705.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EMR63350.1 - 4.6e-16 58.6 0.5 1.2e-15 57.3 0.5 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EMR63350.1 - 5.9e-11 42.9 5.4 5.9e-11 42.9 5.4 2.4 3 0 0 3 3 3 1 DHHA1 domain DUF1902 PF08972.11 EMR63350.1 - 0.12 12.4 2.2 0.22 11.5 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Methyltransf_28 PF02636.17 EMR63351.1 - 8e-41 140.4 0.0 1.5e-40 139.5 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EMR63351.1 - 0.00063 19.6 0.0 0.0031 17.4 0.0 2.2 3 0 0 3 3 3 1 PRMT5 arginine-N-methyltransferase PALP PF00291.25 EMR63352.1 - 6e-60 203.2 4.8 1e-59 202.4 4.8 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BRF1 PF07741.13 EMR63352.1 - 0.012 15.9 3.9 0.012 15.9 3.9 2.2 3 0 0 3 3 3 0 Brf1-like TBP-binding domain DUF3824 PF12868.7 EMR63352.1 - 0.15 12.7 2.1 0.16 12.6 0.5 1.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Ferlin_C PF16165.5 EMR63352.1 - 0.53 10.2 2.3 1.1 9.2 2.3 1.4 1 0 0 1 1 1 0 Ferlin C-terminus U1snRNP70_N PF12220.8 EMR63352.1 - 0.56 10.9 8.2 0.17 12.6 4.4 2.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2956 PF11169.8 EMR63352.1 - 0.8 9.9 10.3 0.77 10.0 7.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF3682 PF12446.8 EMR63352.1 - 2.4 8.6 14.6 0.16 12.5 6.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3682) RNA_pol_Rbc25 PF08292.12 EMR63352.1 - 5 7.4 5.5 1.6 9.0 2.2 1.7 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 TFIIS_M PF07500.14 EMR63353.1 - 1.5e-26 93.1 1.7 3e-26 92.1 1.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EMR63353.1 - 6.9e-18 64.2 8.3 6.9e-18 64.2 8.3 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EMR63353.1 - 1.3e-07 31.5 0.4 1.3e-07 31.5 0.4 2.4 2 1 1 3 3 3 1 TFIIS helical bundle-like domain Sgf11 PF08209.11 EMR63353.1 - 0.46 10.1 6.4 7.5 6.2 1.4 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) 4HBT_2 PF13279.6 EMR63354.1 - 7e-08 33.0 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily ELO PF01151.18 EMR63356.1 - 3.1e-62 210.3 14.4 4.1e-62 209.9 14.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ABC_tran PF00005.27 EMR63358.1 - 2.2e-40 138.4 0.0 1e-20 74.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR63358.1 - 5.4e-25 88.6 11.5 5.4e-25 88.6 11.5 1.8 2 1 1 3 3 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 EMR63358.1 - 6e-11 42.7 4.3 0.0011 18.8 0.2 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMR63358.1 - 2.1e-07 30.6 6.4 0.1 12.0 0.4 5.1 4 2 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMR63358.1 - 7.3e-07 28.8 0.4 0.011 15.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EMR63358.1 - 1.4e-05 25.3 0.0 0.044 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EMR63358.1 - 4.4e-05 23.7 0.4 0.25 11.5 0.0 3.1 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EMR63358.1 - 4.4e-05 23.5 0.3 0.29 11.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EMR63358.1 - 6.6e-05 23.5 0.0 0.2 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EMR63358.1 - 0.00012 22.1 0.0 0.68 10.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EMR63358.1 - 0.00025 20.9 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EMR63358.1 - 0.00029 20.5 0.2 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EMR63358.1 - 0.00041 19.5 0.1 0.96 8.4 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 EMR63358.1 - 0.00075 19.9 0.1 0.42 11.0 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EMR63358.1 - 0.0016 18.5 0.1 0.22 11.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 EMR63358.1 - 0.0024 17.4 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EMR63358.1 - 0.005 16.2 0.2 0.87 8.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 EMR63358.1 - 0.0056 16.5 0.5 0.54 10.0 0.2 3.0 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 EMR63358.1 - 0.0074 16.8 0.0 2.7 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EMR63358.1 - 0.026 14.2 0.1 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EMR63358.1 - 0.091 12.5 0.1 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase CLP1_P PF16575.5 EMR63358.1 - 0.095 12.5 0.2 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop dNK PF01712.19 EMR63358.1 - 0.11 12.3 0.0 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase PduV-EutP PF10662.9 EMR63358.1 - 0.13 12.0 0.5 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EMR63358.1 - 0.16 11.2 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Septin DUF87 PF01935.17 EMR63358.1 - 0.18 11.9 0.5 0.35 10.9 0.1 1.7 2 0 0 2 2 1 0 Helicase HerA, central domain 7TM_GPCR_Srw PF10324.9 EMR63358.1 - 0.93 8.7 8.8 1.2 8.3 2.6 2.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF3611 PF12263.8 EMR63358.1 - 1.4 8.8 7.6 0.17 11.8 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) EamA PF00892.20 EMR63359.1 - 2.4e-13 50.4 10.2 5.9e-09 36.2 7.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family MFS_1 PF07690.16 EMR63360.1 - 1.4e-06 27.5 11.7 0.00051 19.1 0.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR63360.1 - 0.00099 18.1 0.5 0.0013 17.7 0.5 1.2 1 0 0 1 1 1 1 MFS_1 like family Peptidase_S10 PF00450.22 EMR63361.1 - 5e-37 128.3 0.0 2.6e-36 125.9 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase APH PF01636.23 EMR63361.1 - 2.1e-09 37.7 0.0 8e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EMR63361.1 - 5.4e-05 22.6 0.0 9.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EMR63361.1 - 0.00033 20.3 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Latrophilin PF02354.16 EMR63361.1 - 0.071 12.2 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region DUF3328 PF11807.8 EMR63363.1 - 1.2e-19 71.0 0.0 1.3e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Polyketide_cyc PF03364.20 EMR63364.1 - 2.1e-07 31.2 0.4 12 6.1 0.1 5.8 1 1 4 5 5 5 3 Polyketide cyclase / dehydrase and lipid transport DUF5341 PF17276.2 EMR63364.1 - 0.0066 16.6 9.0 19 5.4 0.1 5.2 1 1 4 5 5 5 1 Family of unknown function (DUF5341) CCD48 PF15799.5 EMR63364.1 - 0.01 14.2 2.4 5.5 5.2 0.1 3.5 1 1 2 4 4 4 0 Coiled-coil domain-containing protein 48 Gemini_AC4_5_2 PF08464.10 EMR63364.1 - 0.063 13.2 1.3 5.2e+02 0.7 0.0 5.3 6 0 0 6 6 6 0 Geminivirus AC4/5 conserved region MAS20 PF02064.15 EMR63364.1 - 0.42 10.7 3.2 7.5 6.7 0.3 2.5 1 1 1 2 2 2 0 MAS20 protein import receptor ESSS PF10183.9 EMR63364.1 - 0.88 9.8 3.9 77 3.6 0.1 3.9 1 1 4 5 5 5 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-NOSIP PF15906.5 EMR63364.1 - 3.5 7.8 5.2 1.4e+02 2.7 0.1 4.3 5 0 0 5 5 5 0 Zinc-finger of nitric oxide synthase-interacting protein DUF3328 PF11807.8 EMR63365.1 - 7.6e-28 97.8 0.0 9.7e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) preATP-grasp_3 PF18301.1 EMR63365.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 pre ATP-grasp 3 domain MFS_1 PF07690.16 EMR63366.1 - 3e-17 62.6 58.3 6.6e-11 41.7 32.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AtuA PF07287.11 EMR63368.1 - 8.2e-129 429.3 0.0 1e-128 429.0 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Aldo_ket_red PF00248.21 EMR63370.1 - 1.1e-17 64.2 0.0 2.5e-16 59.7 0.0 2.0 1 1 0 2 2 2 1 Aldo/keto reductase family Erp_C PF06780.11 EMR63370.1 - 0.024 14.7 0.2 0.05 13.6 0.2 1.5 1 0 0 1 1 1 0 Erp protein C-terminus Com_YlbF PF06133.11 EMR63370.1 - 0.062 13.9 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Beta-lactamase PF00144.24 EMR63372.1 - 3.2e-34 118.7 0.1 4.6e-34 118.2 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase Nrap_D4 PF17405.2 EMR63374.1 - 3.4e-63 212.9 0.5 5.6e-63 212.1 0.5 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 EMR63374.1 - 2.5e-54 183.4 0.0 9.3e-54 181.6 0.0 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EMR63374.1 - 1.2e-49 168.0 0.0 3.5e-48 163.2 0.0 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 EMR63374.1 - 4.2e-47 160.0 0.1 9.7e-47 158.8 0.0 1.6 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EMR63374.1 - 9.5e-39 133.0 0.0 1.8e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EMR63374.1 - 3.6e-30 104.9 0.0 1.6e-29 102.8 0.0 2.1 2 0 0 2 2 2 1 Nrap protein domain 6 MFS_1 PF07690.16 EMR63375.1 - 2.8e-35 121.9 23.7 4.2e-35 121.3 23.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cu_bind_like PF02298.17 EMR63376.1 - 0.34 10.9 0.8 1.1 9.3 0.8 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain Abhydrolase_4 PF08386.10 EMR63376.1 - 3.1 7.9 5.2 1.9 8.7 0.1 2.9 4 0 0 4 4 4 0 TAP-like protein PH PF00169.29 EMR63377.1 - 0.00012 22.6 0.0 0.0003 21.2 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF5344 PF17279.2 EMR63377.1 - 0.0062 17.1 0.2 0.063 13.9 0.1 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5344) Acyl_CoA_thio PF02551.15 EMR63377.1 - 0.062 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Acyl-CoA thioesterase Prominin PF05478.11 EMR63377.1 - 0.077 10.9 0.2 0.11 10.4 0.2 1.1 1 0 0 1 1 1 0 Prominin tRNA-synt_2b PF00587.25 EMR63378.1 - 1e-32 113.5 0.1 5.4e-30 104.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMR63378.1 - 6.9e-18 64.6 0.1 1.7e-17 63.4 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EMR63378.1 - 1.1e-11 44.6 0.0 2.3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EMR63378.1 - 1e-10 41.5 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain Chordopox_A20R PF05941.13 EMR63378.1 - 0.084 11.8 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus A20R protein DUF1654 PF07867.11 EMR63378.1 - 0.1 12.3 0.1 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) AMP-binding PF00501.28 EMR63379.1 - 5.3e-57 193.3 0.0 8.8e-41 139.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 EMR63379.1 - 7.3e-12 45.5 0.0 1.9e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 EMR63379.1 - 6.9e-09 34.9 0.0 3.4e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Condensation domain Epimerase PF01370.21 EMR63380.1 - 4e-14 52.7 0.0 8e-14 51.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR63380.1 - 6.1e-11 41.8 0.0 9.4e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EMR63380.1 - 2.1e-08 34.3 0.0 3.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EMR63380.1 - 1e-07 31.6 0.2 1.2e-06 28.1 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EMR63380.1 - 1e-07 31.7 0.4 4.4e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMR63380.1 - 1.9e-07 31.2 0.2 2.8e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR63380.1 - 6.4e-07 29.2 0.1 8.7e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EMR63380.1 - 1.2e-06 27.9 0.0 6e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EMR63380.1 - 3.4e-05 23.1 0.0 5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMR63380.1 - 0.011 14.8 0.1 0.23 10.5 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EMR63380.1 - 0.062 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 EMR63381.1 - 0.0038 16.9 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 EMR63381.1 - 0.0039 16.7 1.5 0.0039 16.7 1.5 1.9 2 1 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EMR63381.1 - 0.0072 15.6 0.0 0.062 12.6 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EMR63381.1 - 0.04 13.8 0.0 0.16 11.8 0.0 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF1100 PF06500.11 EMR63381.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 EMR63381.1 - 0.12 11.8 0.3 0.84 9.1 0.1 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 EMR63381.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF3328 PF11807.8 EMR63382.1 - 1.1e-44 152.9 0.8 1.4e-44 152.5 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TPP_enzyme_N PF02776.18 EMR63383.1 - 5.1e-32 110.8 0.1 8.7e-32 110.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMR63383.1 - 2.7e-20 72.5 0.0 7e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EMR63383.1 - 3e-15 56.3 0.1 1e-14 54.6 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1-N PF14463.6 EMR63383.1 - 0.045 13.6 0.1 0.16 11.8 0.1 2.0 1 0 0 1 1 1 0 E1 N-terminal domain OCC1 PF15506.6 EMR63383.1 - 0.072 13.2 2.9 0.98 9.6 0.4 2.8 3 0 0 3 3 3 0 OCC1 family VEGFR-2_TMD PF17988.1 EMR63384.1 - 0.094 12.2 1.0 0.15 11.5 1.0 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain TGF_beta_GS PF08515.12 EMR63384.1 - 0.26 10.8 2.0 0.62 9.6 2.0 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif SKG6 PF08693.10 EMR63384.1 - 0.43 10.0 6.4 1.6 8.2 6.4 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Gar1 PF04410.14 EMR63385.1 - 2.7e-35 121.4 0.0 3.3e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Loricrin PF15847.5 EMR63385.1 - 3.3 6.7 70.9 0.011 14.9 47.4 2.4 2 0 0 2 2 2 0 Major keratinocyte cell envelope protein Arylsulfotran_2 PF14269.6 EMR63386.1 - 1.5e-42 146.0 1.0 2.2e-42 145.5 1.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMR63386.1 - 2.1e-15 56.5 0.1 4.2e-14 52.2 0.1 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Peptidase_C14 PF00656.22 EMR63387.1 - 2e-64 217.9 0.0 2.5e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EMR63387.1 - 0.091 12.7 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain TLD PF07534.16 EMR63388.1 - 8.4e-24 84.4 0.0 2.5e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 TLD DciA PF05258.12 EMR63389.1 - 0.17 12.3 0.0 1.9 9.0 0.0 2.8 2 1 0 2 2 2 0 Dna[CI] antecedent, DciA YccV-like PF08755.11 EMR63390.1 - 9.6e-18 64.5 0.0 2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EMR63390.1 - 4.5e-15 55.6 0.0 1.3e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box PF00646.33 EMR63390.1 - 0.11 12.4 1.6 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EMR63390.1 - 0.4 10.6 2.7 6.2 6.8 2.7 2.6 1 1 0 1 1 1 0 F-box-like EI24 PF07264.11 EMR63391.1 - 1.4e-09 38.4 3.2 1.9e-09 38.0 3.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ADH_N PF08240.12 EMR63392.1 - 4.9e-09 36.0 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR63392.1 - 6.7e-08 32.6 0.1 1.2e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMR63392.1 - 0.001 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Evr1_Alr PF04777.13 EMR63393.1 - 1.6e-30 105.5 0.6 1.6e-30 105.5 0.6 1.5 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.6 EMR63393.1 - 0.016 15.3 0.2 0.12 12.4 0.0 2.1 2 1 0 2 2 2 0 Bd3614-like deaminase Adeno_PV PF03910.13 EMR63393.1 - 0.041 12.6 0.3 0.042 12.6 0.3 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV MFS_1 PF07690.16 EMR63394.1 - 4.2e-09 35.8 3.7 5.1e-09 35.5 3.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4233 PF14017.6 EMR63394.1 - 0.058 13.7 2.1 0.081 13.3 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Glyco_hydro_43 PF04616.14 EMR63395.1 - 6.5e-09 35.5 9.1 2.7e-05 23.6 2.5 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Polysacc_syn_2C PF08485.10 EMR63395.1 - 0.096 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal DUF3328 PF11807.8 EMR63396.1 - 4.7e-52 177.0 0.4 5.8e-52 176.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FATC PF02260.20 EMR63396.1 - 0.028 14.2 0.1 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 FATC domain CoA_trans PF01144.23 EMR63397.1 - 5.7e-98 326.6 0.4 4.9e-61 205.9 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EMR63397.1 - 0.0024 17.8 0.0 0.01 15.8 0.0 1.8 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain adh_short_C2 PF13561.6 EMR63398.1 - 5.9e-24 84.9 0.1 7.2e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR63398.1 - 2.6e-17 62.9 0.0 3.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR63398.1 - 1.1e-05 25.5 0.0 6.5e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 KR domain Abhydrolase_6 PF12697.7 EMR63399.1 - 5.1e-06 27.3 0.9 8.6e-06 26.5 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR63399.1 - 0.0022 17.3 0.1 0.0062 15.8 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Csa1 PF06023.12 EMR63400.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 TUG-UBL1 PF11470.8 EMR63400.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain PACT_coil_coil PF10495.9 EMR63401.1 - 8.4e-29 100.0 0.4 8.4e-29 100.0 0.4 4.2 4 0 0 4 4 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Cnn_1N PF07989.11 EMR63401.1 - 8.9e-26 89.9 4.1 8.9e-26 89.9 4.1 16.2 2 1 11 15 15 12 3 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 EMR63401.1 - 1.3e-06 28.5 213.6 0.012 15.7 4.7 13.1 4 2 7 12 12 12 8 TPR/MLP1/MLP2-like protein HMMR_N PF15905.5 EMR63401.1 - 1.4e-05 24.8 176.7 0.016 14.7 36.1 10.3 3 2 6 9 9 9 4 Hyaluronan mediated motility receptor N-terminal MscS_porin PF12795.7 EMR63401.1 - 1.9e-05 24.3 209.0 8.1e-05 22.3 26.0 8.7 2 1 4 7 7 5 4 Mechanosensitive ion channel porin domain Spc7 PF08317.11 EMR63401.1 - 0.00013 20.9 194.3 0.00071 18.5 27.1 9.7 1 1 12 13 13 13 7 Spc7 kinetochore protein DUF2046 PF09755.9 EMR63401.1 - 0.00046 19.5 28.2 0.00046 19.5 28.2 6.4 1 1 4 5 5 3 1 Uncharacterized conserved protein H4 (DUF2046) CENP-F_leu_zip PF10473.9 EMR63401.1 - 0.0011 19.1 16.8 0.0011 19.1 16.8 10.6 2 2 7 9 9 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EMR63401.1 - 0.0024 17.2 29.6 0.0024 17.2 29.6 10.1 1 1 7 9 9 9 4 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EMR63401.1 - 0.0033 17.4 118.3 0.011 15.8 6.2 10.8 3 2 6 11 11 11 5 Laminin Domain II Halo_GVPC PF05465.13 EMR63401.1 - 0.036 14.3 7.6 8.4 6.8 0.1 5.8 5 0 0 5 5 5 0 Halobacterial gas vesicle protein C (GVPC) repeat HsbA PF12296.8 EMR63401.1 - 0.04 14.4 20.3 1.6 9.2 0.1 6.1 5 1 1 6 6 6 0 Hydrophobic surface binding protein A MAD PF05557.13 EMR63401.1 - 0.072 11.5 190.3 0.71 8.2 102.2 7.3 1 1 4 5 5 5 0 Mitotic checkpoint protein Lebercilin PF15619.6 EMR63401.1 - 0.12 12.0 206.7 0.1 12.2 9.1 10.1 4 3 4 8 8 8 0 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.12 EMR63401.1 - 1.2 7.2 133.5 1.9 6.6 25.7 6.5 1 1 4 5 5 5 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 EMR63401.1 - 3 7.9 103.5 0.048 13.7 5.2 11.3 2 2 10 13 13 13 0 Protein of unknown function (DUF1664) DUF2013 PF09431.10 EMR63402.1 - 7.7e-50 168.7 1.8 7.7e-50 168.7 1.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Clr5 PF14420.6 EMR63403.1 - 7.5e-20 70.9 1.0 1.5e-19 70.0 1.0 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_10 PF13374.6 EMR63403.1 - 0.022 14.6 0.1 10 6.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Asparaginase_C PF17763.1 EMR63403.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Glyco_hydro_cc PF11790.8 EMR63404.1 - 5.1e-45 153.9 0.5 6.3e-45 153.6 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PhyH PF05721.13 EMR63406.1 - 1.5e-10 41.7 0.1 3.4e-10 40.5 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_92 PF07971.12 EMR63407.1 - 1.1e-150 502.7 0.0 1.2e-150 502.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Pectate_lyase_3 PF12708.7 EMR63408.1 - 5.5e-94 314.0 17.3 3.3e-82 275.5 6.6 3.0 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EMR63408.1 - 9.4e-08 31.6 2.8 0.0072 16.0 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase U62_UL91 PF17442.2 EMR63409.1 - 0.15 12.1 0.6 0.52 10.3 0.0 2.1 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins Dynamin_N PF00350.23 EMR63410.1 - 1.3e-30 106.6 0.0 2.4e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EMR63410.1 - 2.2e-11 43.5 0.7 5.3e-05 22.6 0.0 2.8 3 1 0 4 4 4 2 Dynamin central region MMR_HSR1 PF01926.23 EMR63410.1 - 0.00014 21.9 0.1 0.00072 19.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 EMR63410.1 - 0.001 19.2 0.1 0.038 14.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_21 PF13304.6 EMR63410.1 - 0.02 14.7 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMR63410.1 - 0.15 12.4 0.0 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MitMem_reg PF13012.6 EMR63411.1 - 3.4e-12 46.8 0.3 7.8e-12 45.6 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EMR63411.1 - 1.6e-07 31.3 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Acp26Ab PF05777.12 EMR63411.1 - 0.098 13.3 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Cupin_2 PF07883.11 EMR63412.1 - 8.3e-18 63.9 0.1 1.6e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EMR63412.1 - 9.4e-07 28.8 0.1 1.3e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EMR63412.1 - 7.1e-05 22.4 0.0 8.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 EMR63412.1 - 0.00013 21.7 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.14 EMR63412.1 - 0.00028 21.1 0.4 0.00055 20.1 0.0 1.6 2 0 0 2 2 2 1 ARD/ARD' family Cupin_3 PF05899.12 EMR63412.1 - 0.0012 18.5 0.1 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) JmjC PF02373.22 EMR63412.1 - 0.01 16.2 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase 2-Hacid_dh_C PF02826.19 EMR63414.1 - 2.1e-40 138.0 0.0 3.6e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR63414.1 - 1.8e-26 92.3 0.0 2.4e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Tmemb_14 PF03647.13 EMR63414.1 - 1.6e-19 70.4 4.4 3e-19 69.5 4.4 1.4 1 0 0 1 1 1 1 Transmembrane proteins 14C IlvN PF07991.12 EMR63414.1 - 0.029 14.0 0.0 0.18 11.4 0.0 2.2 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 EMR63414.1 - 0.032 14.3 0.5 0.13 12.4 0.5 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 EMR63414.1 - 0.1 13.2 0.0 0.3 11.7 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent VASt PF16016.5 EMR63415.1 - 2.2e-38 132.1 0.1 3.5e-38 131.4 0.1 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EMR63415.1 - 3.4e-24 84.9 0.0 6e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain ADH_N PF08240.12 EMR63416.1 - 2.7e-25 88.4 1.6 5.4e-25 87.4 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR63416.1 - 3.2e-15 56.3 0.1 1e-10 41.7 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR63416.1 - 9e-09 35.1 1.0 0.00021 20.8 0.1 2.5 3 0 0 3 3 3 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EMR63416.1 - 0.00076 18.8 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EMR63416.1 - 0.0086 17.1 0.0 0.017 16.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EMR63416.1 - 0.019 14.5 0.3 0.04 13.5 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 EMR63416.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.6 EMR63416.1 - 0.075 13.3 0.7 0.27 11.5 0.7 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EMR63416.1 - 0.091 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EMR63416.1 - 0.26 11.2 0.5 0.39 10.6 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CENP-Q PF13094.6 EMR63417.1 - 0.0014 18.9 0.6 0.0014 18.9 0.6 3.4 3 1 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit NRBF2_MIT PF17169.4 EMR63417.1 - 0.0021 18.2 0.7 0.0057 16.8 0.7 1.8 1 0 0 1 1 1 1 MIT domain of nuclear receptor-binding factor 2 Cep57_MT_bd PF06657.13 EMR63417.1 - 2 8.9 5.2 3.4 8.2 0.5 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Dor1 PF04124.12 EMR63417.1 - 2.8 6.6 5.8 1.1 7.9 0.2 2.5 3 0 0 3 3 3 0 Dor1-like family Spc24 PF08286.11 EMR63417.1 - 3 8.1 6.9 3.2 8.1 0.1 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 MIT PF04212.18 EMR63417.1 - 4.9 7.3 6.4 2.5 8.2 1.8 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DivIVA PF05103.13 EMR63417.1 - 5.5 7.1 10.0 1.6 8.8 0.1 3.0 3 0 0 3 3 3 0 DivIVA protein DUF5111 PF17138.4 EMR63418.1 - 0.0077 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5111) SMC_Nse1 PF07574.13 EMR63419.1 - 3.8e-65 219.4 0.1 5.3e-65 219.0 0.1 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EMR63419.1 - 6.5e-15 55.2 11.3 1e-14 54.5 11.3 1.3 1 0 0 1 1 1 1 RING-like domain FYDLN_acid PF09538.10 EMR63419.1 - 0.00046 20.8 3.0 0.0011 19.7 3.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) DUF2161 PF09929.9 EMR63419.1 - 0.061 13.4 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) zf-HC5HC2H PF13771.6 EMR63419.1 - 0.74 10.1 7.1 2.1 8.7 7.1 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 EMR63419.1 - 1.1 9.6 9.3 1.4 9.4 8.2 1.7 2 0 0 2 2 2 0 Ring finger domain Vps5 PF09325.10 EMR63420.1 - 1.3e-12 47.8 0.2 1.9e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EMR63420.1 - 3.4e-08 33.5 0.0 6.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 PX domain NST1 PF13945.6 EMR63420.1 - 0.15 12.2 1.5 0.24 11.5 1.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Cyclin_N PF00134.23 EMR63421.1 - 0.033 13.9 0.0 0.089 12.5 0.0 1.7 1 1 0 1 1 1 0 Cyclin, N-terminal domain GST_N PF02798.20 EMR63422.1 - 1.5e-13 50.9 0.0 2.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR63422.1 - 1.1e-05 25.4 0.1 3.1e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR63422.1 - 1.7e-05 25.0 0.0 2.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR63422.1 - 9e-05 22.6 0.0 0.00019 21.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR63422.1 - 0.00019 21.5 0.0 0.00052 20.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR63422.1 - 0.00021 21.6 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EMR63422.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EFG_II PF14492.6 EMR63423.1 - 4.8e-21 74.6 0.0 1.1e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU PF00009.27 EMR63423.1 - 1.7e-17 63.6 0.0 2.6e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EMR63423.1 - 1.1e-14 54.3 0.0 5e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus RF3_C PF16658.5 EMR63423.1 - 9.1e-07 28.8 0.0 3.1e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 EMR63423.1 - 0.00025 21.4 0.0 0.001 19.4 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Kelch_5 PF13854.6 EMR63425.1 - 5.6e-18 64.5 8.5 4.5e-08 32.9 0.2 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EMR63425.1 - 6.8e-10 39.0 13.5 0.043 14.1 0.2 5.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EMR63425.1 - 1.1e-08 35.0 4.3 0.36 10.9 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EMR63425.1 - 3.5e-08 33.4 11.5 0.033 14.5 0.2 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EMR63425.1 - 2.1e-07 30.4 9.4 0.012 15.2 0.2 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EMR63425.1 - 0.00063 19.6 10.3 0.1 12.6 0.1 5.1 7 0 0 7 7 7 2 Kelch motif SKG6 PF08693.10 EMR63425.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Zn-ribbon_8 PF09723.10 EMR63427.1 - 0.0017 18.4 3.2 0.12 12.5 0.8 2.5 2 0 0 2 2 2 2 Zinc ribbon domain zf-RING_7 PF02591.15 EMR63427.1 - 0.087 13.0 1.8 5.7 7.2 0.5 2.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain DZR PF12773.7 EMR63427.1 - 0.098 12.7 0.4 6.5 6.9 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-TFIIB PF13453.6 EMR63427.1 - 0.11 11.8 1.0 3.4 7.1 0.1 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger UBA_3 PF09288.10 EMR63428.1 - 0.3 10.9 0.9 1.4 8.8 0.1 2.5 4 0 0 4 4 4 0 Fungal ubiquitin-associated domain CUE PF02845.16 EMR63429.1 - 2.6e-11 43.0 0.0 4.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 EMR63429.1 - 0.17 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) OPT PF03169.15 EMR63430.1 - 1.3e-168 562.5 49.6 1.7e-168 562.1 49.6 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FlgM PF04316.13 EMR63430.1 - 0.00026 21.3 0.5 0.00051 20.3 0.5 1.5 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM AMP-binding PF00501.28 EMR63431.1 - 1.5e-35 122.6 0.0 1.9e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme TFR_dimer PF04253.15 EMR63432.1 - 9.7e-31 106.4 0.0 2.1e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EMR63432.1 - 5.9e-14 52.2 0.0 1.7e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMR63432.1 - 2.4e-11 43.5 0.2 6.5e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 PA domain ERM PF00769.19 EMR63433.1 - 4.9e-05 23.3 7.4 5.8e-05 23.0 7.4 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 EMR63433.1 - 0.0019 18.8 3.8 0.018 15.7 1.3 2.1 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 RasGAP_C PF03836.15 EMR63433.1 - 0.0043 17.2 0.4 0.0053 16.9 0.4 1.2 1 0 0 1 1 1 1 RasGAP C-terminus FapA PF03961.13 EMR63433.1 - 0.0069 15.0 0.2 0.0072 15.0 0.2 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A SHE3 PF17078.5 EMR63433.1 - 0.0071 16.1 2.3 0.0078 15.9 2.3 1.0 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Seryl_tRNA_N PF02403.22 EMR63433.1 - 0.013 15.7 3.1 0.03 14.5 0.9 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 EMR63433.1 - 0.016 15.2 2.7 0.11 12.5 0.6 2.0 1 1 1 2 2 2 0 Laminin Domain II DUF745 PF05335.13 EMR63433.1 - 0.017 14.8 4.4 0.022 14.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TMPIT PF07851.13 EMR63433.1 - 0.017 14.4 0.8 0.021 14.1 0.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 EMR63433.1 - 0.021 15.4 1.2 0.028 15.0 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA DivIVA PF05103.13 EMR63433.1 - 0.023 14.8 1.8 0.023 14.8 1.8 1.8 1 1 1 2 2 2 0 DivIVA protein DUF4201 PF13870.6 EMR63433.1 - 0.028 14.2 1.8 0.028 14.2 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) OmpH PF03938.14 EMR63433.1 - 0.029 14.7 1.8 0.037 14.4 1.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V-SNARE PF05008.15 EMR63433.1 - 0.034 14.5 3.6 6.1 7.3 1.9 2.4 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Prefoldin_2 PF01920.20 EMR63433.1 - 0.042 13.8 2.9 0.4 10.7 1.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 EMR63433.1 - 0.043 13.9 12.1 1.3 9.1 12.1 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.6 EMR63433.1 - 0.055 13.7 8.5 0.069 13.4 8.5 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Leu_zip PF15294.6 EMR63433.1 - 0.059 12.9 5.1 0.18 11.3 5.0 1.6 1 1 0 1 1 1 0 Leucine zipper Csm1_N PF18504.1 EMR63433.1 - 0.061 13.7 2.5 0.061 13.7 2.5 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain Dzip-like_N PF13815.6 EMR63433.1 - 0.064 13.2 1.1 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal GAS PF13851.6 EMR63433.1 - 0.065 12.6 4.7 0.096 12.0 4.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ufd2P_core PF10408.9 EMR63433.1 - 0.071 11.7 0.1 0.085 11.4 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core PRKG1_interact PF15898.5 EMR63433.1 - 0.072 14.0 4.6 0.095 13.6 4.6 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Sec2p PF06428.11 EMR63433.1 - 0.083 12.9 4.8 2 8.4 0.5 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CSN5_C PF18323.1 EMR63433.1 - 0.099 13.6 0.7 0.13 13.2 0.7 1.3 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain TSC22 PF01166.18 EMR63433.1 - 0.14 12.5 1.5 0.29 11.5 0.3 2.2 1 1 2 3 3 3 0 TSC-22/dip/bun family CHIP_TPR_N PF18391.1 EMR63433.1 - 0.15 12.8 7.0 1.2 10.0 1.6 2.1 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DivIC PF04977.15 EMR63433.1 - 0.2 11.4 5.9 0.11 12.3 2.5 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF724 PF05266.14 EMR63433.1 - 0.2 11.4 3.0 0.26 11.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 EMR63433.1 - 0.22 9.4 0.9 0.25 9.2 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PspA_IM30 PF04012.12 EMR63433.1 - 0.31 10.6 10.3 0.9 9.1 10.3 1.7 1 1 0 1 1 1 0 PspA/IM30 family Golgin_A5 PF09787.9 EMR63433.1 - 0.34 10.4 5.3 0.37 10.2 5.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc24 PF08286.11 EMR63433.1 - 0.4 10.9 9.0 2.9 8.2 9.0 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4337 PF14235.6 EMR63433.1 - 0.51 10.4 7.2 1.7 8.7 7.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4140 PF13600.6 EMR63433.1 - 0.56 10.7 6.5 0.25 11.8 2.2 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 EMR63433.1 - 0.57 9.0 7.1 0.93 8.3 7.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 EMR63433.1 - 0.67 10.0 6.7 1.8 8.7 6.6 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding XhlA PF10779.9 EMR63433.1 - 0.84 9.9 5.9 4.3 7.6 1.7 2.2 2 0 0 2 2 2 0 Haemolysin XhlA APG6_N PF17675.1 EMR63433.1 - 1.2 9.7 13.3 3.7 8.1 13.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 EMR63433.1 - 1.6 9.2 8.9 5.4 7.5 8.9 2.0 1 1 0 1 1 1 0 Cell division protein ZapB End3 PF12761.7 EMR63433.1 - 2.3 8.3 9.6 1.3 9.2 1.6 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 TMF_DNA_bd PF12329.8 EMR63433.1 - 3 7.9 10.1 16 5.6 10.1 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Vps35 PF03635.17 EMR63434.1 - 0 1033.2 0.0 0 1033.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Meth_synt_2 PF01717.18 EMR63435.1 - 1e-13 51.3 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EMR63435.1 - 0.0035 16.9 0.1 0.09 12.3 0.0 2.6 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain SNARE PF05739.19 EMR63436.1 - 5e-10 39.2 1.3 8.2e-10 38.5 1.3 1.4 1 0 0 1 1 1 1 SNARE domain HrpB7 PF09486.10 EMR63436.1 - 3.3 8.1 19.3 0.77 10.1 11.5 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) LysM PF01476.20 EMR63437.1 - 2.3e-31 107.6 0.1 2.2e-06 27.6 0.0 5.8 6 0 0 6 6 6 4 LysM domain HTH_23 PF13384.6 EMR63437.1 - 5.6e-08 32.4 0.0 0.2 11.5 0.0 3.5 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 EMR63437.1 - 5.6e-07 29.6 0.7 0.32 11.2 0.1 3.9 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EMR63437.1 - 3e-06 27.4 0.0 0.37 11.1 0.0 4.1 4 0 0 4 4 4 2 Transposase NLPC_P60 PF00877.19 EMR63437.1 - 0.00033 20.6 1.0 19 5.4 0.0 4.7 5 0 0 5 5 5 0 NlpC/P60 family CarbpepA_inh PF02977.15 EMR63437.1 - 0.0075 16.0 16.0 3.4 7.5 2.2 5.2 5 0 0 5 5 5 2 Carboxypeptidase A inhibitor DUF1153 PF06627.11 EMR63437.1 - 0.0091 16.1 0.0 25 5.1 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1153) CENP-B_N PF04218.13 EMR63437.1 - 0.028 14.0 0.0 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 EMR63437.1 - 0.031 14.3 0.0 8.4 6.6 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase UPF0203 PF05254.12 EMR63437.1 - 0.078 13.2 3.1 21 5.4 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0203) DUF4383 PF14325.6 EMR63437.1 - 0.12 12.6 0.2 5.2 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) HTH_29 PF13551.6 EMR63437.1 - 0.16 12.1 0.3 12 6.0 0.0 3.2 3 0 0 3 3 3 0 Winged helix-turn helix zf-TFIIB PF13453.6 EMR63437.1 - 2.4 7.6 7.4 25 4.3 0.1 3.9 4 0 0 4 4 4 0 Transcription factor zinc-finger LprI PF07007.12 EMR63438.1 - 0.034 14.8 0.5 0.034 14.8 0.5 2.3 3 0 0 3 3 3 0 Lysozyme inhibitor LprI Glyco_hydro_18 PF00704.28 EMR63439.1 - 1.9e-47 162.6 0.2 2.8e-47 162.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EMR63439.1 - 3.9e-05 23.6 0.0 0.34 11.0 0.1 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 EMR63439.1 - 0.0032 17.9 8.8 0.0032 17.9 8.8 3.3 4 0 0 4 4 4 1 Chitin recognition protein DUF3165 PF11364.8 EMR63439.1 - 0.13 12.6 2.0 0.22 11.9 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) Metaviral_G PF09595.10 EMR63440.1 - 0.095 12.8 0.9 0.15 12.1 0.9 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein Cep57_CLD_2 PF14197.6 EMR63440.1 - 0.36 11.0 3.2 0.64 10.1 3.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF3784 PF12650.7 EMR63440.1 - 0.45 10.7 5.0 0.81 9.9 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Hydrolase_4 PF12146.8 EMR63441.1 - 1.5e-14 53.9 0.1 3.5e-09 36.3 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR63441.1 - 1.5e-10 41.2 0.1 3.4e-07 30.2 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 EMR63441.1 - 7.5e-05 22.4 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EMR63441.1 - 8.3e-05 23.3 0.0 0.0005 20.7 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 EMR63441.1 - 8.5e-05 21.4 0.1 0.83 8.3 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DUF818 PF05677.12 EMR63441.1 - 0.00041 19.4 0.0 0.00059 18.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_5 PF12695.7 EMR63441.1 - 0.00044 20.1 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EMR63441.1 - 0.00088 19.2 0.0 0.0018 18.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR63441.1 - 0.0025 17.3 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 EMR63441.1 - 0.0035 17.1 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EMR63441.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 EMR63441.1 - 0.087 12.7 0.0 3.2 7.6 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Amidoligase_2 PF12224.8 EMR63442.1 - 1.6e-13 50.9 0.0 1.8e-10 40.9 0.0 2.6 2 1 0 2 2 2 2 Putative amidoligase enzyme Pex2_Pex12 PF04757.14 EMR63443.1 - 2.3e-41 141.9 2.7 3.1e-41 141.4 2.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EMR63443.1 - 1.4e-11 44.0 8.8 2.8e-11 43.1 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR63443.1 - 4.3e-11 42.5 5.1 6.9e-11 41.8 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMR63443.1 - 1.3e-10 41.4 8.6 2.6e-10 40.5 8.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EMR63443.1 - 3.8e-10 39.5 6.3 7.2e-10 38.6 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR63443.1 - 2.6e-08 33.7 7.8 5.8e-08 32.6 7.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EMR63443.1 - 4e-08 33.0 6.6 6.6e-08 32.3 6.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EMR63443.1 - 3.4e-07 30.1 4.6 6.4e-07 29.2 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EMR63443.1 - 3.3e-06 27.3 6.5 8.5e-06 26.0 6.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EMR63443.1 - 7.2e-06 26.1 8.1 1.3e-05 25.2 8.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EMR63443.1 - 0.0032 17.5 5.7 0.0066 16.6 5.7 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EMR63443.1 - 0.014 15.3 1.7 0.027 14.3 1.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 EMR63443.1 - 0.028 14.2 2.8 0.068 12.9 2.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger Transposase_23 PF03017.14 EMR63443.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 TNP1/EN/SPM transposase zf-RING_4 PF14570.6 EMR63443.1 - 0.82 9.5 8.5 1.7 8.5 8.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EXS PF03124.14 EMR63444.1 - 1.2e-106 356.8 3.9 1.4e-106 356.6 3.9 1.0 1 0 0 1 1 1 1 EXS family PIG-P PF08510.12 EMR63444.1 - 1.8 8.5 5.5 4.6 7.2 5.5 1.7 1 0 0 1 1 1 0 PIG-P MR_MLE_C PF13378.6 EMR63445.1 - 4.1e-59 199.8 0.1 4.9e-59 199.6 0.1 1.0 1 0 0 1 1 1 1 Enolase C-terminal domain-like F-box-like PF12937.7 EMR63446.1 - 0.00055 19.8 0.4 0.0025 17.7 0.4 2.3 1 0 0 1 1 1 1 F-box-like Peptidase_M43 PF05572.13 EMR63447.1 - 1.7e-18 67.0 1.9 2.8e-18 66.3 1.6 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 EMR63447.1 - 0.00019 21.3 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 EMR63447.1 - 0.00039 20.9 0.3 0.0017 18.8 0.1 1.9 1 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EMR63447.1 - 0.0004 20.1 0.2 0.00077 19.2 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EMR63447.1 - 0.00083 19.6 4.2 0.0011 19.2 4.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EMR63447.1 - 0.0049 16.8 0.2 0.007 16.3 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EMR63447.1 - 0.028 13.4 1.4 0.041 12.8 1.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 EMR63447.1 - 0.077 11.6 0.4 0.11 11.1 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase family AveC_like PF17198.4 EMR63447.1 - 0.09 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Spirocyclase AveC-like Cyt-b5 PF00173.28 EMR63448.1 - 4.2e-13 49.2 0.0 5.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Terpene_synth_C PF03936.16 EMR63449.1 - 0.0049 16.3 0.2 0.0088 15.4 0.0 1.5 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Abhydrolase_3 PF07859.13 EMR63450.1 - 2.5e-53 181.1 0.0 3.2e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR63450.1 - 3e-05 23.6 0.0 8.9e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EMR63450.1 - 0.00066 18.7 0.9 0.0017 17.3 0.1 1.8 1 1 1 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 EMR63450.1 - 0.0092 15.3 0.0 0.11 11.7 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 EMR63450.1 - 0.022 14.3 0.0 0.053 13.1 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EMR63450.1 - 0.12 13.0 4.5 0.16 12.5 3.8 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 EMR63450.1 - 0.18 10.5 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_transf_15 PF01793.16 EMR63453.1 - 1.7e-85 287.2 1.1 4e-85 285.9 1.1 1.5 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 EMR63453.1 - 0.21 11.8 1.6 0.34 11.2 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) zf-LYAR PF08790.11 EMR63454.1 - 2.9e-08 33.5 0.4 5.5e-08 32.6 0.4 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Hep_59 PF07052.11 EMR63454.1 - 2.5 8.9 0.0 2.5 8.9 0.0 3.2 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 MFS_1 PF07690.16 EMR63455.1 - 2.2e-23 82.7 30.0 6.6e-17 61.5 15.3 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR63455.1 - 1.3e-09 37.5 2.2 1.3e-08 34.2 0.3 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2615 PF11027.8 EMR63455.1 - 0.011 15.9 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) OATP PF03137.20 EMR63455.1 - 0.014 13.7 2.3 0.19 10.0 2.2 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NicO PF03824.16 EMR63455.1 - 0.02 14.3 0.8 0.089 12.1 0.0 2.3 2 1 1 3 3 3 0 High-affinity nickel-transport protein 7TM_GPCR_Srv PF10323.9 EMR63455.1 - 0.11 11.9 0.9 0.2 11.0 0.1 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv Ferrochelatase PF00762.19 EMR63456.1 - 7.1e-76 255.3 0.0 2e-52 178.3 0.0 2.0 1 1 1 2 2 2 2 Ferrochelatase Ku PF02735.16 EMR63457.1 - 1.6e-41 142.3 0.0 5e-41 140.6 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EMR63457.1 - 4e-33 115.0 0.2 7.9e-33 114.0 0.2 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EMR63457.1 - 6.8e-25 87.6 2.6 6.8e-25 87.6 2.6 2.4 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EMR63457.1 - 1e-10 41.1 1.4 1e-10 41.1 1.4 2.2 2 0 0 2 2 2 1 SAP domain LETM1 PF07766.13 EMR63457.1 - 0.056 12.8 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 LETM1-like protein HeH PF12949.7 EMR63457.1 - 0.2 11.4 0.7 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 HeH/LEM domain Het-C PF07217.11 EMR63459.1 - 1.7e-269 895.1 0.1 1.2e-268 892.3 0.1 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C RabGAP-TBC PF00566.18 EMR63460.1 - 3.3e-51 174.0 0.0 4.5e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Porphobil_deamC PF03900.15 EMR63460.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Glyco_tranf_2_3 PF13641.6 EMR63461.1 - 1.8e-15 57.5 0.0 2.1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMR63461.1 - 0.0018 18.1 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EMR63461.1 - 0.01 15.4 0.1 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 p450 PF00067.22 EMR63462.1 - 6.4e-43 147.2 0.0 8.6e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_5 PF06172.11 EMR63463.1 - 2.4e-47 160.7 0.0 2.7e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) GYF PF02213.16 EMR63464.1 - 5.4e-17 61.2 0.3 1.1e-16 60.2 0.3 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EMR63464.1 - 0.057 13.2 0.8 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 GYF domain 2 CN_hydrolase PF00795.22 EMR63465.1 - 1.1e-22 80.7 0.6 7.4e-22 77.9 0.6 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase V-SNARE_C PF12352.8 EMR63468.1 - 1.6e-14 54.0 3.0 3.3e-14 52.9 0.2 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EMR63468.1 - 1.4e-05 24.9 0.0 4.4e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Sec20 Mito_fiss_reg PF05308.11 EMR63468.1 - 0.033 14.3 0.9 0.049 13.7 0.1 1.7 1 1 0 2 2 2 0 Mitochondrial fission regulator Sigma70_r4 PF04545.16 EMR63468.1 - 0.034 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 E2F_TDP PF02319.20 EMR63468.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain DUF745 PF05335.13 EMR63468.1 - 0.34 10.6 2.5 3.9 7.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TPR_MLP1_2 PF07926.12 EMR63468.1 - 1.7 8.7 5.5 3.7 7.6 0.6 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein TPR_16 PF13432.6 EMR63469.1 - 1.6e-10 41.5 1.5 1.6e-10 41.5 1.5 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR63469.1 - 1.7e-06 27.6 0.4 0.0063 16.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR63469.1 - 5.8e-06 26.0 7.2 0.0051 16.8 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMR63469.1 - 4.7e-05 23.6 5.1 0.00077 19.7 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMR63469.1 - 0.00014 22.4 2.8 0.018 15.8 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMR63469.1 - 0.00045 20.3 0.3 0.0019 18.3 0.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMR63469.1 - 0.017 14.8 0.1 0.69 9.7 0.0 3.4 3 2 0 3 3 3 0 TPR repeat TPR_7 PF13176.6 EMR63469.1 - 0.018 15.1 0.1 9.6 6.5 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMR63469.1 - 0.046 13.9 0.0 0.78 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMR63469.1 - 0.091 13.3 2.4 0.83 10.2 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMR63469.1 - 2.6 8.0 10.5 27 4.8 1.6 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C12 PF01088.21 EMR63470.1 - 1.4e-51 175.2 0.0 3.7e-35 121.6 0.0 2.5 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase, family 1 TMEM214 PF10151.9 EMR63470.1 - 0.036 12.6 4.3 0.053 12.0 4.3 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator FemAB PF02388.16 EMR63470.1 - 0.036 12.9 0.1 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 FemAB family DotU PF09850.9 EMR63470.1 - 0.22 11.2 1.4 0.32 10.7 0.1 1.9 2 0 0 2 2 2 0 Type VI secretion system protein DotU Mito_carr PF00153.27 EMR63471.1 - 6.5e-58 192.7 4.9 1.1e-21 76.6 0.1 4.0 2 2 2 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EMR63471.1 - 0.00046 19.4 2.5 0.29 10.3 0.3 3.1 1 1 1 3 3 3 2 Gammaproteobacterial serine protease DUF5011 PF16403.5 EMR63472.1 - 0.21 11.7 1.8 1.5 9.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5011) ILVD_EDD PF00920.21 EMR63473.1 - 0.028 13.0 0.3 0.039 12.6 0.3 1.1 1 0 0 1 1 1 0 Dehydratase family CDP-OH_P_transf PF01066.21 EMR63474.1 - 1.5e-12 48.1 0.3 3.5e-12 46.9 0.3 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase HET PF06985.11 EMR63475.1 - 5e-31 108.0 0.2 9.2e-31 107.2 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APG9 PF04109.16 EMR63476.1 - 1e-69 235.8 1.6 1.2e-69 235.6 1.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF2722 PF10846.8 EMR63476.1 - 0.018 14.0 0.2 0.022 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 EMR63476.1 - 0.023 14.3 6.3 0.039 13.6 6.3 1.3 1 0 0 1 1 1 0 Spt20 family Fungal_trans_2 PF11951.8 EMR63477.1 - 2.5e-10 39.7 0.3 7.7e-10 38.1 0.0 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR63477.1 - 3e-06 27.2 12.3 3e-06 27.2 12.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta_protein PF14350.6 EMR63477.1 - 0.031 13.7 0.2 0.062 12.7 0.0 1.5 2 0 0 2 2 2 0 Beta protein Spt20 PF12090.8 EMR63477.1 - 0.68 9.5 8.1 0.024 14.2 2.1 1.6 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 EMR63477.1 - 0.94 9.6 10.4 2.6 8.2 10.4 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FA_desaturase PF00487.24 EMR63478.1 - 7.5e-24 84.9 28.5 8.3e-24 84.8 27.7 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EMR63478.1 - 7.5e-09 35.6 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Metallopep PF12044.8 EMR63480.1 - 1.6e-145 485.0 0.0 1.8e-145 484.8 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 EMR63480.1 - 0.042 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain Reprolysin_5 PF13688.6 EMR63480.1 - 0.055 13.6 0.4 0.085 13.0 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Inh PF02974.14 EMR63480.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protease inhibitor Inh Secretin_N_2 PF07655.13 EMR63481.1 - 5.2 7.7 10.5 0.19 12.3 2.6 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Syndecan PF01034.20 EMR63483.1 - 0.29 11.1 0.7 0.52 10.3 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 EMR63483.1 - 1.9 8.0 10.5 1.8 8.0 1.1 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DnaJ PF00226.31 EMR63484.1 - 2.9e-21 75.3 1.1 9.5e-21 73.7 1.1 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_8 PF13181.6 EMR63484.1 - 4.2e-14 51.5 3.2 0.086 13.1 0.0 7.3 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMR63484.1 - 3e-12 45.8 5.9 0.0043 16.8 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMR63484.1 - 2.4e-11 42.9 13.4 0.011 15.7 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMR63484.1 - 2e-09 37.5 0.5 2.8e-05 24.2 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMR63484.1 - 7.8e-08 31.9 8.4 0.0021 17.7 0.1 4.9 3 1 2 5 5 5 2 TPR repeat TPR_17 PF13431.6 EMR63484.1 - 8.3e-08 32.1 2.6 0.00051 20.2 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMR63484.1 - 1.5e-07 31.7 11.6 0.024 15.5 0.1 6.4 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMR63484.1 - 6.7e-07 29.7 10.7 0.081 13.4 0.0 5.0 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EMR63484.1 - 1e-06 28.3 7.5 0.00075 19.4 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EMR63484.1 - 1.3e-06 27.4 0.1 0.0025 16.6 0.0 2.6 1 1 0 2 2 2 2 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 EMR63484.1 - 1.7e-06 28.2 4.3 0.56 11.0 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR63484.1 - 9.1e-05 23.0 14.8 0.052 14.2 0.0 5.1 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMR63484.1 - 0.016 15.5 12.8 0.13 12.6 0.2 5.5 4 2 1 5 5 5 0 Tetratricopeptide repeat IFT46_B_C PF12317.8 EMR63484.1 - 0.035 13.8 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal BTAD PF03704.17 EMR63484.1 - 0.11 12.9 7.5 4 7.9 0.0 4.5 3 1 1 5 5 5 0 Bacterial transcriptional activator domain DUF3856 PF12968.7 EMR63484.1 - 0.14 12.3 3.2 1.6 8.8 0.2 3.6 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 EMR63484.1 - 0.81 10.0 12.1 3.6 7.9 0.0 4.4 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 HemY_N PF07219.13 EMR63484.1 - 1.6 9.0 7.3 0.38 11.0 0.7 3.1 3 1 0 3 3 3 0 HemY protein N-terminus Glyco_hydro_71 PF03659.14 EMR63485.1 - 1.3e-87 294.0 0.0 1.6e-87 293.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 COG6 PF06419.11 EMR63486.1 - 7.4e-219 728.1 5.4 8.4e-219 727.9 5.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DASH_Dad3 PF08656.10 EMR63486.1 - 0.025 14.7 2.6 0.087 12.9 0.1 3.0 3 1 0 3 3 3 0 DASH complex subunit Dad3 Med9 PF07544.13 EMR63486.1 - 0.055 13.6 1.6 0.12 12.5 0.4 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CRISPR_Cas2 PF09827.9 EMR63486.1 - 0.062 13.5 0.0 13 6.1 0.0 3.1 3 0 0 3 3 3 0 CRISPR associated protein Cas2 COG2 PF06148.11 EMR63486.1 - 0.096 12.8 2.5 0.26 11.4 1.0 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5595 PF18077.1 EMR63486.1 - 0.1 12.7 0.4 20 5.3 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DASH_Duo1 PF08651.10 EMR63486.1 - 0.12 12.1 1.2 5.3 6.9 0.6 3.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF2894 PF11445.8 EMR63486.1 - 0.39 11.2 5.2 1.3 9.4 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2894) Whi5 PF08528.11 EMR63487.1 - 2.7e-09 36.5 0.2 4.8e-09 35.6 0.2 1.5 1 0 0 1 1 1 1 Whi5 like CBS PF00571.28 EMR63488.1 - 8.7e-05 22.9 0.1 0.22 12.0 0.0 3.1 2 1 1 3 3 3 2 CBS domain AA_permease_2 PF13520.6 EMR63489.1 - 1.5e-73 248.1 40.2 1.9e-73 247.8 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR63489.1 - 4.2e-06 25.6 38.3 1.3e-05 24.1 38.3 1.9 1 1 0 1 1 1 1 Amino acid permease SurE PF01975.17 EMR63490.1 - 2.3e-33 115.6 0.0 3.1e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.6 EMR63490.1 - 0.013 15.9 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain PGM_PMM_I PF02878.16 EMR63491.1 - 6.1e-34 116.7 0.0 9e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EMR63491.1 - 5.3e-26 91.1 0.0 9.5e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EMR63491.1 - 1.8e-14 54.2 0.0 3.7e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EMR63491.1 - 4.2e-05 23.6 0.0 9.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glyco_hydro_cc PF11790.8 EMR63492.1 - 8e-28 97.6 0.1 9.5e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core VbhA PF18495.1 EMR63492.1 - 0.4 10.6 2.3 6.9 6.6 0.2 3.1 3 0 0 3 3 3 0 Antitoxin VbhA MFS_1 PF07690.16 EMR63493.1 - 4e-20 72.0 42.0 1.4e-19 70.3 41.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR63493.1 - 1.5e-08 33.9 13.2 1.5e-08 33.9 13.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Polysacc_lyase PF14099.6 EMR63494.1 - 2.8e-46 158.0 11.0 3.2e-46 157.8 11.0 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Methyltransf_25 PF13649.6 EMR63496.1 - 9.1e-12 45.5 0.0 4.8e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EMR63496.1 - 1.2e-09 38.7 0.0 0.0014 19.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EMR63496.1 - 3.3e-09 36.8 0.0 4.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR63496.1 - 4.3e-09 37.0 0.0 8.3e-08 32.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMR63496.1 - 0.00023 20.6 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EMR63496.1 - 0.0003 20.6 0.0 0.00068 19.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EMR63496.1 - 0.0067 16.0 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_33 PF10017.9 EMR63496.1 - 0.014 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_7 PF03492.15 EMR63496.1 - 0.024 13.9 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Ubie_methyltran PF01209.18 EMR63496.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 EMR63496.1 - 0.15 11.4 0.0 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB SUIM_assoc PF16619.5 EMR63497.1 - 0.42 10.7 6.3 0.12 12.4 0.9 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ank_5 PF13857.6 EMR63498.1 - 4.8e-14 52.2 0.1 1.9e-12 47.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR63498.1 - 7.2e-06 26.5 0.7 0.0031 18.0 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) VPS9 PF02204.18 EMR63498.1 - 3.7e-05 23.9 0.1 8.4e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_4 PF13637.6 EMR63498.1 - 8.1e-05 23.1 0.1 0.0055 17.3 0.1 3.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR63498.1 - 0.00019 21.6 0.3 0.35 11.6 0.0 4.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EMR63498.1 - 0.00049 20.4 0.7 2.3 8.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DUF3035 PF11233.8 EMR63498.1 - 0.05 13.9 0.3 0.11 12.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) RNase_T PF00929.24 EMR63499.1 - 1.3e-26 94.1 0.1 1.5e-26 93.9 0.1 1.0 1 0 0 1 1 1 1 Exonuclease RRP7 PF12923.7 EMR63499.1 - 0.17 12.0 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Cupin_2 PF07883.11 EMR63500.1 - 4.4e-07 29.5 0.0 6.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EMR63500.1 - 0.0011 18.7 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) cNMP_binding PF00027.29 EMR63500.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain SLC3A2_N PF16028.5 EMR63501.1 - 6.7 6.3 6.7 0.83 9.2 0.3 2.4 2 1 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus adh_short PF00106.25 EMR63503.1 - 7.5e-21 74.5 0.0 8.8e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63503.1 - 1e-14 54.6 0.0 1.3e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR63503.1 - 1.3e-06 28.5 0.0 2.5e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMR63503.1 - 0.0035 16.8 0.0 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR63503.1 - 0.005 16.7 0.1 0.0085 16.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EMR63503.1 - 0.044 12.9 0.0 0.095 11.8 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Abhydrolase_3 PF07859.13 EMR63504.1 - 1.3e-06 28.4 1.3 1.9e-06 27.9 1.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR63504.1 - 3e-05 23.1 0.0 5.8e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DEAD PF00270.29 EMR63505.1 - 1.8e-32 112.5 0.2 4.1e-22 78.8 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR63505.1 - 1.3e-23 83.5 0.0 1.1e-22 80.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMR63505.1 - 9e-20 70.7 0.4 1.9e-19 69.7 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EMR63505.1 - 0.035 14.1 0.0 0.53 10.3 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF2457 PF10446.9 EMR63505.1 - 0.043 13.0 17.3 0.062 12.4 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 EMR63505.1 - 5.3 6.3 23.1 7.6 5.8 23.1 1.1 1 0 0 1 1 1 0 BUD22 DIOX_N PF14226.6 EMR63506.1 - 8.1e-09 36.3 0.0 1.5e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR63506.1 - 1.1e-07 32.3 0.0 2.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CysA_C_terminal PF17850.1 EMR63506.1 - 0.066 13.8 1.2 0.19 12.3 0.5 2.2 2 0 0 2 2 2 0 CysA C-terminal regulatory domain FAA_hydrolase PF01557.18 EMR63508.1 - 8.5e-46 156.3 0.0 1.1e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 2OG-FeII_Oxy_3 PF13640.6 EMR63510.1 - 1.6e-08 35.3 0.0 3.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2116 PF09889.9 EMR63511.1 - 0.41 10.7 1.1 33 4.6 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Cellulase PF00150.18 EMR63512.1 - 6e-12 45.6 1.5 1.4e-11 44.4 1.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.25 EMR63513.1 - 2.2e-16 59.9 0.1 6.7e-16 58.3 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMR63513.1 - 1.6e-09 37.9 0.2 2.2e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMR63513.1 - 2.1e-08 34.0 0.2 9.5e-07 28.6 0.2 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GTP1_OBG PF01018.22 EMR63513.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 GTP1/OBG F-box PF00646.33 EMR63514.1 - 0.0018 18.1 0.1 0.009 15.9 0.0 2.2 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 EMR63514.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like Alpha_L_fucos PF01120.17 EMR63515.1 - 3.3e-30 105.7 0.0 1.1e-29 104.0 0.0 1.7 1 1 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 EMR63515.1 - 5.9e-12 45.8 1.1 2e-11 44.1 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain Methyltransf_25 PF13649.6 EMR63518.1 - 7.4e-09 36.2 0.1 4.1e-08 33.8 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR63518.1 - 1.1e-06 29.2 0.1 2.3e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR63518.1 - 3e-05 24.7 0.1 0.00012 22.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR63518.1 - 0.0038 17.0 0.1 0.0058 16.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.32 EMR63520.1 - 2e-41 139.2 17.0 7.7e-07 29.7 0.4 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 EMR63520.1 - 1.2e-11 44.1 2.1 3.5e-11 42.7 0.9 2.4 2 1 1 3 3 3 1 F-box domain F-box-like PF12937.7 EMR63520.1 - 9.2e-11 41.5 0.3 1.7e-10 40.6 0.3 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EMR63520.1 - 1e-09 38.6 0.6 0.22 11.8 0.0 5.3 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR63520.1 - 0.00065 18.5 7.5 2.6 6.6 0.0 5.2 3 1 2 5 5 5 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EMR63520.1 - 0.0013 18.3 2.9 0.91 9.1 0.0 3.4 3 1 1 4 4 4 2 PQQ-like domain F-box_4 PF15966.5 EMR63520.1 - 0.016 15.0 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 F-box DUF4597 PF15366.6 EMR63520.1 - 0.061 13.1 0.1 1.1 9.1 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) GST_N PF02798.20 EMR63521.1 - 1.9e-15 57.0 0.0 4.2e-14 52.6 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR63521.1 - 4.9e-14 52.5 0.0 2.6e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR63521.1 - 1.5e-11 44.3 0.0 3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR63521.1 - 2.1e-11 44.0 0.0 4.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR63521.1 - 2e-08 34.3 0.0 4.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR63521.1 - 5e-08 32.9 0.1 8.6e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EMR63521.1 - 0.0034 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PMP1_2 PF08114.11 EMR63522.1 - 0.0075 16.0 0.5 0.016 15.0 0.5 1.5 1 0 0 1 1 1 1 ATPase proteolipid family EphA2_TM PF14575.6 EMR63522.1 - 0.15 13.0 0.6 0.58 11.1 0.7 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Arylsulfotran_2 PF14269.6 EMR63523.1 - 3.7e-55 187.4 3.3 4.6e-55 187.1 3.3 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMR63523.1 - 2.9e-17 62.6 1.9 1.1e-16 60.7 1.9 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DAO PF01266.24 EMR63524.1 - 6.9e-26 91.7 6.8 1.5e-25 90.5 6.8 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR63524.1 - 0.0048 16.2 0.1 0.068 12.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4126 PF13548.6 EMR63524.1 - 0.013 15.3 0.3 0.06 13.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) Pyr_redox_2 PF07992.14 EMR63524.1 - 0.063 12.5 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR63524.1 - 0.086 13.1 0.4 0.34 11.2 0.4 2.1 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 4HBT PF03061.22 EMR63525.1 - 0.067 13.6 0.5 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Thioesterase superfamily Pirin PF02678.16 EMR63530.1 - 2.5e-30 104.6 0.0 4.2e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EMR63530.1 - 3e-25 88.6 0.0 1.1e-23 83.5 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EMR63530.1 - 1.9e-06 27.5 0.4 3.2e-05 23.6 0.2 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EMR63530.1 - 0.07 12.8 0.1 0.4 10.4 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF861) eIF3_p135 PF12807.7 EMR63531.1 - 0.054 13.5 0.6 0.16 12.0 0.4 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 Spt20 PF12090.8 EMR63531.1 - 0.091 12.4 8.5 0.18 11.4 8.5 1.4 1 0 0 1 1 1 0 Spt20 family Secretin_N_2 PF07655.13 EMR63531.1 - 0.18 12.4 14.4 4.1 8.0 0.4 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Presenilin PF01080.17 EMR63531.1 - 0.46 9.2 2.3 0.36 9.6 0.4 1.7 2 0 0 2 2 2 0 Presenilin DUF4834 PF16118.5 EMR63531.1 - 0.49 11.4 5.6 2 9.4 5.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAD_binding_3 PF01494.19 EMR63532.1 - 4e-24 85.5 0.0 9.5e-24 84.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR63532.1 - 1.1e-09 38.0 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR63532.1 - 2.3e-08 34.0 0.1 6.7e-07 29.2 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR63532.1 - 8.2e-07 28.1 0.0 0.00012 21.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 EMR63532.1 - 1.2e-06 28.1 0.0 8.1e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR63532.1 - 1.4e-06 27.7 0.0 4.4e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EMR63532.1 - 9.9e-06 25.7 0.0 2.9e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR63532.1 - 1.5e-05 24.6 0.1 3.9e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMR63532.1 - 0.00036 19.7 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EMR63532.1 - 0.0018 17.4 0.0 0.9 8.5 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMR63532.1 - 0.0057 16.7 0.1 0.064 13.3 0.1 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMR63532.1 - 0.0086 16.6 0.0 0.1 13.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMR63532.1 - 0.024 13.9 0.0 0.05 12.9 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EMR63532.1 - 0.072 11.9 0.1 2.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ABC_tran PF00005.27 EMR63533.1 - 3.4e-45 153.9 0.1 6.7e-23 81.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EMR63533.1 - 6.8e-30 102.9 0.2 2.2e-29 101.3 0.2 2.0 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 EMR63533.1 - 3.4e-18 66.5 0.0 0.0018 18.2 0.0 5.3 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMR63533.1 - 4.7e-15 55.6 0.3 0.00013 21.5 0.1 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMR63533.1 - 2e-10 41.5 5.9 2.1e-05 25.1 0.5 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EMR63533.1 - 1.1e-08 34.7 0.1 0.0051 16.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMR63533.1 - 2.8e-07 30.6 0.0 0.002 18.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMR63533.1 - 3.2e-07 30.4 0.0 0.0027 17.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EMR63533.1 - 7.2e-07 29.5 0.0 0.018 15.4 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 EMR63533.1 - 1.5e-06 28.6 0.0 0.019 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EMR63533.1 - 2.4e-06 27.7 0.0 0.00023 21.3 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 EMR63533.1 - 1.7e-05 25.3 0.1 0.19 12.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 EMR63533.1 - 2.5e-05 24.7 0.0 0.49 10.8 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EMR63533.1 - 4.7e-05 23.3 3.6 0.058 13.1 0.1 3.3 3 2 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 EMR63533.1 - 4.8e-05 23.6 0.0 0.54 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 EMR63533.1 - 7.2e-05 21.9 0.1 0.24 10.4 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EMR63533.1 - 7.4e-05 23.2 0.0 0.35 11.2 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain PduV-EutP PF10662.9 EMR63533.1 - 7.8e-05 22.5 0.0 0.067 12.9 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EMR63533.1 - 0.00014 22.2 0.0 1.2 9.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 EMR63533.1 - 0.0002 21.0 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMR63533.1 - 0.00046 20.1 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 EMR63533.1 - 0.00057 19.9 0.0 2.3 8.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EMR63533.1 - 0.00057 19.7 0.0 0.94 9.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 EMR63533.1 - 0.00063 19.0 0.1 1.2 8.2 0.0 2.7 3 1 0 3 3 2 2 G-protein alpha subunit AAA_30 PF13604.6 EMR63533.1 - 0.00064 19.5 0.0 2.6 7.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 EMR63533.1 - 0.0015 18.7 1.1 0.83 9.7 0.1 3.3 4 0 0 4 4 2 1 Helicase HerA, central domain Rad17 PF03215.15 EMR63533.1 - 0.0031 17.5 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Septin PF00735.18 EMR63533.1 - 0.0031 16.8 0.6 3.8 6.7 0.0 3.4 3 0 0 3 3 3 0 Septin cobW PF02492.19 EMR63533.1 - 0.0052 16.4 0.3 4 7.0 0.0 3.0 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EMR63533.1 - 0.0078 15.4 0.1 0.41 9.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 EMR63533.1 - 0.0088 16.3 0.0 2 8.7 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EMR63533.1 - 0.0093 16.2 0.0 5.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 EMR63533.1 - 0.0096 15.7 0.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 EMR63533.1 - 0.015 15.1 0.2 7.3 6.3 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EMR63533.1 - 0.015 15.2 0.0 3.9 7.3 0.0 3.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EMR63533.1 - 0.015 15.0 0.0 9.4 5.9 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein CLP1_P PF16575.5 EMR63533.1 - 0.017 14.9 1.3 0.75 9.6 0.0 2.8 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 EMR63533.1 - 0.024 14.2 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 EMR63533.1 - 0.025 13.3 2.4 2.3 6.8 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EMR63533.1 - 0.031 13.9 0.0 3.9 7.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 EMR63533.1 - 0.035 13.7 0.1 3.4 7.3 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 EMR63533.1 - 0.055 13.4 0.1 14 5.5 0.1 2.8 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 EMR63533.1 - 0.057 13.1 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 EMR63533.1 - 0.068 12.4 0.1 11 5.3 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin DUF815 PF05673.13 EMR63533.1 - 0.074 12.2 0.0 12 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EMR63533.1 - 0.087 12.2 0.0 7.8 5.8 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 EMR63533.1 - 0.092 12.7 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FeoB_N PF02421.18 EMR63533.1 - 0.12 11.9 0.2 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B MMS19_C PF12460.8 EMR63533.1 - 0.12 11.4 0.3 17 4.3 0.3 2.8 2 1 1 3 3 3 0 RNAPII transcription regulator C-terminal ParcG PF10274.9 EMR63533.1 - 0.18 11.9 0.3 2.8 8.0 0.1 2.5 1 1 1 2 2 2 0 Parkin co-regulated protein BDHCT PF08072.11 EMR63533.1 - 0.5 10.5 4.3 2.2 8.4 0.2 2.8 2 0 0 2 2 2 0 BDHCT (NUC031) domain CAF1C_H4-bd PF12265.8 EMR63535.1 - 9.8e-25 86.6 2.1 1.6e-23 82.7 0.2 3.7 4 1 0 4 4 4 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EMR63535.1 - 1.6e-20 73.0 9.4 2.2e-05 25.1 0.4 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR63535.1 - 2e-06 28.0 0.9 0.0017 18.6 0.1 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4059 PF13268.6 EMR63535.1 - 0.25 11.8 0.1 0.81 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) CENP-I PF07778.11 EMR63536.1 - 8.8e-15 54.4 0.0 1.8e-12 46.8 0.0 2.8 1 1 2 3 3 3 3 Mis6 NYAP_N PF15439.6 EMR63537.1 - 0.24 10.6 5.4 0.05 12.8 2.4 1.4 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DUF410 PF04190.13 EMR63538.1 - 1.8e-90 303.2 0.0 2.2e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Aminotran_1_2 PF00155.21 EMR63539.1 - 3.7e-08 32.9 0.0 1e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Cse1 PF08506.10 EMR63540.1 - 1.3e-155 517.8 3.3 2e-155 517.2 3.3 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 EMR63540.1 - 8.3e-126 420.0 0.0 6.6e-75 252.3 0.0 2.3 1 1 1 2 2 2 2 CAS/CSE protein, C-terminus IBN_N PF03810.19 EMR63540.1 - 2.8e-13 49.6 0.1 9.3e-13 47.9 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EMR63540.1 - 0.0049 16.9 2.2 0.43 10.6 0.0 4.1 4 1 0 4 4 4 1 Exportin 1-like protein TetR_C_13 PF16925.5 EMR63540.1 - 0.11 12.4 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CAF1A PF12253.8 EMR63541.1 - 2e-22 79.1 2.5 2e-22 79.1 2.5 3.8 4 0 0 4 4 4 1 Chromatin assembly factor 1 subunit A Bud13 PF09736.9 EMR63541.1 - 0.025 15.0 18.0 0.06 13.7 18.0 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2981 PF11200.8 EMR63541.1 - 0.27 10.9 11.8 0.49 10.1 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4778 PF16008.5 EMR63541.1 - 1.1 9.3 9.5 1.7 8.6 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) GBP_C PF02841.14 EMR63541.1 - 2.5 7.4 23.6 4.5 6.6 23.6 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Presenilin PF01080.17 EMR63541.1 - 7.4 5.2 12.5 11 4.7 12.5 1.2 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 EMR63541.1 - 9.2 6.0 15.0 22 4.7 15.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_60s PF00428.19 EMR63542.1 - 0.038 14.6 3.3 0.081 13.5 3.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein RAI1 PF08652.11 EMR63543.1 - 5e-28 97.1 0.1 2.1e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Aromatic_hydrox PF11723.8 EMR63543.1 - 0.046 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase MTHFR PF02219.17 EMR63544.1 - 3.7e-99 331.7 0.0 7.6e-99 330.6 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase DUF3295 PF11702.8 EMR63544.1 - 0.78 9.0 2.9 0.24 10.7 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) TB2_DP1_HVA22 PF03134.19 EMR63545.1 - 2.2e-27 94.8 10.2 3.6e-27 94.1 10.2 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bestrophin PF01062.21 EMR63545.1 - 0.0096 15.3 0.4 0.014 14.8 0.4 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel ABC_tran PF00005.27 EMR63546.1 - 7.6e-16 58.9 0.0 7.8e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMR63546.1 - 6.2e-10 39.4 0.2 0.00016 21.6 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMR63546.1 - 0.00066 19.4 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 EMR63546.1 - 0.001 16.7 0.2 0.0014 16.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SMC_N PF02463.19 EMR63546.1 - 0.0078 15.7 0.0 3.3 7.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EMR63546.1 - 0.0082 16.4 0.2 0.017 15.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMR63546.1 - 0.0093 16.5 0.0 0.013 16.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Phi-29_GP4 PF05464.11 EMR63546.1 - 0.014 15.7 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) AAA_16 PF13191.6 EMR63546.1 - 0.016 15.6 0.5 0.03 14.7 0.5 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EMR63546.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 EMR63546.1 - 0.031 14.0 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EMR63546.1 - 0.032 14.7 0.1 0.11 12.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMR63546.1 - 0.036 14.3 0.2 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EMR63546.1 - 0.04 13.5 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EMR63546.1 - 0.054 13.4 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EMR63546.1 - 0.072 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EMR63546.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_13 PF13166.6 EMR63546.1 - 0.12 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMR63546.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMR63546.1 - 0.2 11.6 0.2 0.35 10.8 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AA_kinase PF00696.28 EMR63548.1 - 6.2e-37 127.5 0.5 1.7e-36 126.0 0.0 1.8 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 EMR63548.1 - 7.2e-15 54.5 2.2 4.3e-08 32.8 0.1 3.4 2 1 1 3 3 3 2 ACT domain ACT_7 PF13840.6 EMR63548.1 - 9.5e-13 47.7 5.2 1.3e-09 37.7 0.4 2.6 2 0 0 2 2 2 2 ACT domain DUF3384 PF11864.8 EMR63549.1 - 4.1e-141 471.2 0.0 8.4e-141 470.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EMR63549.1 - 2.8e-55 186.7 0.0 1.6e-54 184.3 0.0 2.1 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.16 EMR63549.1 - 2e-12 46.9 0.4 1.5e-10 40.8 0.2 2.3 2 0 0 2 2 2 2 Tuberin IF4E PF01652.18 EMR63550.1 - 1.3e-52 177.8 0.2 1.8e-52 177.3 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1917 PF08939.10 EMR63550.1 - 0.065 13.1 1.2 0.084 12.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) XRN_N PF03159.18 EMR63551.1 - 4.3e-97 324.3 0.0 7.3e-97 323.5 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EMR63551.1 - 1.2e-76 256.7 0.0 2.3e-76 255.9 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN_M PF17846.1 EMR63551.1 - 3.9e-69 233.7 6.7 1.2e-34 120.1 0.1 2.3 1 1 1 2 2 2 2 Xrn1 helical domain XRN1_D2_D3 PF18334.1 EMR63551.1 - 3.7e-33 113.6 0.0 8.9e-33 112.4 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EMR63551.1 - 2.1e-21 75.8 0.1 4.9e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EMR63551.1 - 6.3e-07 29.4 0.8 2.6e-06 27.4 0.3 2.3 2 0 0 2 2 2 1 Exoribonuclease 1 Domain-3 Glyco_hydro_3_C PF01915.22 EMR63552.1 - 5e-46 157.2 0.0 1.5e-45 155.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR63552.1 - 8.2e-38 130.6 0.0 1.3e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR63552.1 - 4.5e-23 81.2 0.8 8.8e-23 80.2 0.8 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain NOA36 PF06524.12 EMR63553.1 - 1.7 7.9 3.1 2.9 7.1 3.1 1.3 1 0 0 1 1 1 0 NOA36 protein zf-RanBP PF00641.18 EMR63554.1 - 2.5e-18 65.1 13.3 8.6e-11 41.0 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EMR63554.1 - 3.2e-08 33.3 0.0 6.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 EMR63554.1 - 3.2e-05 24.6 0.0 4.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Kin17_mid PF10357.9 EMR63555.1 - 2.5e-31 108.2 6.4 2.8e-21 75.7 0.0 2.9 2 1 1 3 3 3 2 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 EMR63555.1 - 2.3e-05 24.5 0.2 4.4e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMR63555.1 - 3.7e-05 24.0 0.8 6.4e-05 23.2 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EMR63555.1 - 0.0056 17.0 0.2 0.01 16.2 0.2 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 EMR63555.1 - 0.13 11.4 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Putative actin-like family CiPC PF15800.5 EMR63555.1 - 0.56 9.9 11.1 0.91 9.2 11.1 1.3 1 0 0 1 1 1 0 Clock interacting protein circadian Acetyltransf_1 PF00583.25 EMR63556.1 - 2e-06 28.0 0.0 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR63556.1 - 0.00015 22.1 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR63556.1 - 0.00033 20.7 0.0 0.0033 17.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR63556.1 - 0.00095 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EMR63556.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 EMR63556.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Glyco_hydro_88 PF07470.13 EMR63557.1 - 3.5e-13 49.3 0.4 1.7e-12 47.1 0.4 1.8 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Ribosomal_L4 PF00573.22 EMR63558.1 - 2.2e-35 122.1 0.2 2.9e-35 121.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EMR63558.1 - 9.4e-28 96.1 0.3 9.4e-28 96.1 0.3 1.7 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Peptidase_M35 PF02102.15 EMR63559.1 - 4.7e-67 226.4 22.3 1.6e-66 224.6 22.3 1.6 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EMR63559.1 - 1.9e-42 145.2 6.1 3.4e-42 144.4 6.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase IceA2 PF05862.11 EMR63559.1 - 0.11 12.5 1.9 24 5.0 0.0 3.3 3 0 0 3 3 3 0 Helicobacter pylori IceA2 protein TOBE_2 PF08402.10 EMR63559.1 - 0.12 12.6 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 TOBE domain DUF4131 PF13567.6 EMR63559.1 - 0.18 11.4 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Cyclase PF04199.13 EMR63560.1 - 1.1e-07 32.2 0.0 1.5e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 EMR63561.1 - 2.3e-65 221.2 12.7 2.6e-65 221.0 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1996 PF09362.10 EMR63562.1 - 2.3e-72 243.8 0.1 3.6e-72 243.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EMR63562.1 - 2.3e-30 104.6 24.1 1.9e-15 56.8 9.7 2.6 2 0 0 2 2 2 2 WSC domain Peptidase_M1_N PF17900.1 EMR63563.1 - 8.7e-08 32.6 0.0 0.0015 18.8 0.0 2.8 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EMR63563.1 - 0.00034 20.3 0.0 0.00069 19.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT PF02985.22 EMR63563.1 - 0.029 14.6 0.1 13 6.3 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 EMR63563.1 - 0.066 13.6 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats MatP PF06303.12 EMR63563.1 - 0.22 12.1 1.2 0.69 10.5 1.2 1.8 1 0 0 1 1 1 0 MatP N-terminal domain PsiA PF06952.11 EMR63563.1 - 0.82 8.9 3.0 1.5 8.0 3.0 1.3 1 0 0 1 1 1 0 PsiA protein ERO1 PF04137.15 EMR63564.1 - 1.9e-136 455.0 0.0 2.5e-136 454.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Prok-TraM PF09228.10 EMR63564.1 - 0.084 13.2 0.5 0.25 11.7 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM TSGP1 PF07771.11 EMR63564.1 - 2.4 8.3 6.9 0.23 11.6 0.3 2.3 2 0 0 2 2 2 0 Tick salivary peptide group 1 Fasciclin PF02469.22 EMR63565.1 - 0.0064 16.7 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain Adenyl_transf PF04439.12 EMR63566.1 - 0.043 12.9 0.1 0.072 12.2 0.1 1.3 1 0 0 1 1 1 0 Streptomycin adenylyltransferase DUF3176 PF11374.8 EMR63567.1 - 2.6e-26 91.9 0.0 2.6e-26 91.9 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3176) YycH PF07435.11 EMR63567.1 - 0.06 12.3 0.1 0.086 11.8 0.1 1.1 1 0 0 1 1 1 0 YycH protein FAD_binding_2 PF00890.24 EMR63568.1 - 2.2e-85 287.3 0.7 2.7e-85 287.0 0.7 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EMR63568.1 - 7.5e-22 77.3 0.0 6.6e-21 74.2 0.0 2.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EMR63568.1 - 2e-13 50.6 1.0 4.5e-13 49.5 1.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EMR63568.1 - 1.6e-10 41.0 1.0 8.1e-10 38.6 1.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR63568.1 - 4.4e-08 32.7 1.0 4.4e-07 29.4 0.4 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR63568.1 - 2.5e-07 30.8 3.0 4.3e-07 30.1 0.6 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR63568.1 - 7.5e-07 28.7 0.0 0.023 14.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR63568.1 - 5.1e-05 22.7 1.4 0.00011 21.6 1.4 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMR63568.1 - 0.00025 20.4 1.0 0.03 13.6 0.5 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EMR63568.1 - 0.00031 19.6 4.1 0.014 14.2 0.3 3.2 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 EMR63568.1 - 0.00098 18.3 2.8 0.13 11.4 1.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 EMR63568.1 - 0.0023 17.3 0.8 0.45 9.8 0.2 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EMR63568.1 - 0.0088 16.6 5.4 1.8 9.2 1.8 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMR63568.1 - 0.069 12.4 2.0 0.13 11.6 2.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 EMR63569.1 - 9.5e-12 44.1 0.0 1.6e-10 40.0 0.0 2.7 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMR63569.1 - 6.7e-10 39.1 0.2 2.2e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR63569.1 - 2.2e-07 30.4 0.0 6.3e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR63569.1 - 3.7e-05 23.1 0.0 0.0003 20.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR63569.1 - 0.0095 15.9 0.1 1 9.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EMR63569.1 - 0.034 13.3 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EMR63569.1 - 0.037 13.3 0.1 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Thi4 family SAS4 PF15460.6 EMR63570.1 - 1.4e-05 25.1 0.1 1.4e-05 25.1 0.1 2.3 1 1 1 2 2 2 1 Something about silencing, SAS, complex subunit 4 Nop14 PF04147.12 EMR63570.1 - 0.011 14.0 18.3 0.014 13.6 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_primase_lrg PF04104.14 EMR63570.1 - 0.058 12.8 0.5 0.074 12.4 0.5 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit SH3-RhoG_link PF16609.5 EMR63570.1 - 0.11 12.2 4.5 0.15 11.8 4.5 1.2 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region PNISR PF15996.5 EMR63570.1 - 0.12 12.6 14.3 0.21 11.9 14.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CDC45 PF02724.14 EMR63570.1 - 0.17 10.2 15.3 0.23 9.7 15.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 EMR63570.1 - 0.33 10.9 25.9 0.59 10.1 25.9 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TMEM51 PF15345.6 EMR63570.1 - 0.71 9.7 5.3 1.1 9.1 5.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CobT PF06213.12 EMR63570.1 - 1.2 8.4 21.8 0.34 10.3 18.9 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 EMR63570.1 - 1.7 6.6 28.0 2.2 6.3 28.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi PTPRCAP PF15713.5 EMR63570.1 - 6.3 7.1 20.1 11 6.3 20.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 EMR63570.1 - 9.1 5.5 26.7 0.091 12.1 19.0 1.5 2 0 0 2 2 2 0 BUD22 MscS_TM PF12794.7 EMR63570.1 - 9.1 5.0 6.7 13 4.5 6.7 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MIP PF00230.20 EMR63571.1 - 1.1e-44 152.9 12.7 1.3e-44 152.6 12.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1616 PF07760.11 EMR63571.1 - 0.18 11.2 2.7 0.34 10.2 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) MFS_1 PF07690.16 EMR63572.1 - 1e-13 51.0 4.7 1.2e-13 50.7 4.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Egh16-like PF11327.8 EMR63573.1 - 8.4e-53 179.5 3.7 8.4e-53 179.5 3.7 2.1 2 0 0 2 2 1 1 Egh16-like virulence factor CENP-B_dimeris PF09026.10 EMR63573.1 - 0.0079 16.6 7.7 0.024 15.0 7.7 1.8 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EMR63573.1 - 0.0093 15.7 11.3 0.015 15.0 11.3 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 EMR63573.1 - 0.012 15.9 2.5 0.012 15.9 2.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.18 EMR63573.1 - 0.051 13.5 2.1 0.077 12.9 2.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF4637 PF15470.6 EMR63573.1 - 0.21 11.3 3.3 0.49 10.1 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) FAM176 PF14851.6 EMR63573.1 - 0.3 10.8 5.2 0.77 9.4 5.2 1.7 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 EMR63573.1 - 0.87 9.1 11.7 1.3 8.5 11.7 1.2 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.6 EMR63573.1 - 1.1 8.0 4.8 1.5 7.5 4.8 1.2 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 EMR63573.1 - 4.6 5.4 7.2 6 5.0 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EMR63573.1 - 5.3 5.1 13.5 7 4.7 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EMR63573.1 - 5.8 4.9 12.4 7.6 4.5 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Endonuclease_NS PF01223.23 EMR63574.1 - 2.2e-63 214.1 0.0 2.6e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Chitin_synth_2 PF03142.15 EMR63578.1 - 5.1e-44 150.8 6.1 4.4e-41 141.1 6.1 2.0 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EMR63578.1 - 8.8e-06 25.8 8.0 2.1e-05 24.6 8.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMR63578.1 - 2.9e-05 24.0 0.0 0.04 13.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_hydro_18 PF00704.28 EMR63579.1 - 3.7e-58 197.7 0.0 4.2e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_34 PF11312.8 EMR63579.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase E_Pc_C PF06752.12 EMR63579.1 - 0.021 15.0 0.2 0.053 13.6 0.3 1.5 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Metallophos PF00149.28 EMR63582.1 - 2.2e-10 41.4 0.0 3.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMR63582.1 - 0.0024 18.1 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sugar_tr PF00083.24 EMR63583.1 - 2.9e-90 303.3 15.6 3.3e-90 303.1 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR63583.1 - 3.6e-22 78.8 34.5 1.4e-17 63.7 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR63583.1 - 0.0002 20.0 2.9 0.00041 18.9 2.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMR63583.1 - 3.1 6.0 13.1 1.6 6.9 0.2 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family UDPG_MGDP_dh PF00984.19 EMR63584.1 - 7.7e-21 74.1 0.0 1.8e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 EMR63584.1 - 6e-17 61.8 0.1 4.1e-15 55.8 0.1 2.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 EMR63584.1 - 2.8e-05 24.3 0.0 4.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 EMR63584.1 - 9.9e-05 22.7 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TrkA_N PF02254.18 EMR63584.1 - 0.00059 20.1 0.0 0.0033 17.7 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain Methyltransf_25 PF13649.6 EMR63584.1 - 0.0017 19.0 0.0 0.0055 17.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 EMR63584.1 - 0.0066 15.8 0.6 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.12 EMR63584.1 - 0.008 16.8 0.0 0.027 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain F420_oxidored PF03807.17 EMR63584.1 - 0.0083 16.7 0.0 0.044 14.4 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EMR63584.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Anp1 PF03452.14 EMR63585.1 - 3.4e-27 95.5 0.0 5.4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Anp1 FAD_binding_4 PF01565.23 EMR63586.1 - 1.9e-20 73.0 1.0 3.7e-20 72.1 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR63586.1 - 0.01 15.9 0.1 0.026 14.6 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like DUF190 PF02641.15 EMR63586.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 CortBP2 PF09727.9 EMR63587.1 - 0.035 14.0 4.1 0.05 13.5 4.1 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 RNA_polI_A14 PF08203.11 EMR63587.1 - 0.25 12.1 2.6 0.45 11.3 2.5 1.7 1 1 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Fzo_mitofusin PF04799.13 EMR63587.1 - 0.28 10.7 4.7 0.71 9.4 4.8 1.5 1 1 0 1 1 1 0 fzo-like conserved region DUF3106 PF11304.8 EMR63587.1 - 0.64 10.5 9.0 0.97 9.9 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Exonuc_VII_L PF02601.15 EMR63587.1 - 0.76 9.3 3.6 1 8.9 3.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 EMR63587.1 - 4.6 7.1 8.2 0.39 10.5 1.0 2.1 2 0 0 2 2 2 0 Septum formation initiator Bap31_Bap29_C PF18035.1 EMR63587.1 - 6.2 6.9 8.7 1.7 8.7 2.1 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Cir_N PF10197.9 EMR63587.1 - 8.3 6.7 8.3 0.21 11.8 1.1 2.1 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR ZT_dimer PF16916.5 EMR63588.1 - 5.9e-09 35.9 0.3 1.2e-08 35.0 0.3 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 EMR63588.1 - 2.7e-05 24.0 11.3 0.00018 21.3 1.3 2.5 2 1 0 2 2 2 2 Cation efflux family CobS PF02654.15 EMR63588.1 - 0.0052 17.0 1.3 0.012 15.8 1.4 1.5 1 1 0 1 1 1 1 Cobalamin-5-phosphate synthase AAA_12 PF13087.6 EMR63589.1 - 2.1e-54 184.2 0.0 2.9e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMR63589.1 - 3.3e-34 118.9 0.2 1.4e-17 64.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EMR63589.1 - 3.1e-14 53.1 0.0 8.8e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR63589.1 - 1.3e-12 48.3 0.0 2.9e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EMR63589.1 - 1.5e-06 28.1 0.3 0.17 11.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EMR63589.1 - 7.6e-05 22.6 0.0 0.0002 21.3 0.0 1.7 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 EMR63589.1 - 0.00036 20.2 0.0 0.00068 19.3 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 EMR63589.1 - 0.0016 18.1 0.1 0.0028 17.3 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 EMR63589.1 - 0.0023 17.2 0.1 0.024 13.8 0.1 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 EMR63589.1 - 0.0059 17.0 0.0 0.021 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EMR63589.1 - 0.0081 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region CbiA PF01656.23 EMR63589.1 - 0.014 15.5 0.3 0.027 14.5 0.2 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.12 EMR63589.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EMR63589.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMR63589.1 - 0.063 13.3 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EMR63589.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PEPCK_ATP PF01293.20 EMR63589.1 - 0.065 11.9 0.1 0.21 10.2 0.0 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase DUF87 PF01935.17 EMR63589.1 - 0.092 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain DUF2075 PF09848.9 EMR63589.1 - 0.11 11.7 0.0 0.3 10.3 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF853 PF05872.12 EMR63589.1 - 0.12 11.0 0.1 0.19 10.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MeaB PF03308.16 EMR63589.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EMR63589.1 - 0.13 12.2 0.3 0.33 10.9 0.1 1.8 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit Thioredoxin_16 PF18569.1 EMR63589.1 - 0.14 12.3 0.0 0.46 10.6 0.0 1.8 2 0 0 2 2 1 0 Thioredoxin-like domain AAA_33 PF13671.6 EMR63589.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMR63589.1 - 0.17 11.8 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 NTPase DUF21 PF01595.20 EMR63590.1 - 1.7e-33 115.8 0.0 2.5e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EMR63590.1 - 7.9e-05 23.0 0.5 0.0091 16.4 0.0 3.0 2 0 0 2 2 2 2 CBS domain Fungal_trans PF04082.18 EMR63592.1 - 0.00023 20.3 0.0 0.001 18.2 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EMR63593.1 - 5.3e-23 81.4 0.0 1e-22 80.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain COX15-CtaA PF02628.15 EMR63594.1 - 8.2e-111 370.2 7.4 1e-110 369.9 7.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Zip PF02535.22 EMR63595.1 - 7.3e-53 179.9 0.5 9.4e-53 179.6 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Chromo_shadow PF01393.19 EMR63596.1 - 2.3e-20 72.4 2.0 6.2e-19 67.8 0.4 2.5 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 EMR63596.1 - 6e-11 42.1 1.0 6e-11 42.1 1.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain LAT PF15234.6 EMR63596.1 - 0.79 9.4 4.5 1.7 8.4 4.5 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells Glyco_hydro_16 PF00722.21 EMR63597.1 - 5.3e-44 149.8 6.9 5.3e-44 149.8 6.9 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 BAF1_ABF1 PF04684.13 EMR63597.1 - 0.054 12.6 3.6 0.062 12.4 3.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SOBP PF15279.6 EMR63597.1 - 3.4 8.2 7.8 5.1 7.6 7.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF572 PF04502.13 EMR63597.1 - 3.9 7.0 8.5 5.4 6.5 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Tmemb_cc2 PF10267.9 EMR63597.1 - 9 5.3 9.9 12 4.9 9.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SOG2 PF10428.9 EMR63597.1 - 9.1 5.3 18.5 12 4.9 18.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ApbA_C PF08546.11 EMR63598.1 - 2.4e-27 95.6 0.0 7.2e-27 94.1 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EMR63598.1 - 5.9e-11 42.2 0.0 1.2e-10 41.2 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Lactonase PF10282.9 EMR63599.1 - 2.6e-19 69.7 0.0 3.2e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HisKA PF00512.25 EMR63600.1 - 1.5e-12 47.3 1.5 5.8e-12 45.5 0.7 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EMR63600.1 - 2.9e-10 40.3 0.0 3.8e-09 36.7 0.0 2.7 2 1 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EMR63600.1 - 1.1e-09 38.8 0.1 2.2e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_2 PF08446.11 EMR63600.1 - 1e-07 32.5 0.0 3.4e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 EMR63600.1 - 0.0027 18.3 0.0 0.0057 17.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 EMR63600.1 - 0.092 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dioxygenase_C PF00775.21 EMR63601.1 - 1e-42 145.7 0.0 1.5e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EMR63601.1 - 5.5e-20 71.0 0.2 9e-20 70.3 0.2 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EMR63601.1 - 0.00093 19.4 0.1 0.0037 17.5 0.1 2.1 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EMR63601.1 - 0.0044 17.3 0.0 0.008 16.5 0.0 1.4 1 0 0 1 1 1 1 Prealbumin-like fold domain Na_H_Exchanger PF00999.21 EMR63602.1 - 1.9e-16 59.8 21.0 1.4e-12 47.1 16.0 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family RNB PF00773.19 EMR63604.1 - 8e-100 334.3 0.1 1.4e-99 333.6 0.1 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EMR63604.1 - 9e-34 116.3 0.2 2.7e-33 114.7 0.2 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EMR63604.1 - 8.9e-32 108.9 0.1 3.5e-31 107.0 0.1 2.1 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 EMR63604.1 - 3e-21 75.2 0.0 7.7e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EMR63604.1 - 1.3e-11 44.9 0.2 8.3e-11 42.3 0.1 2.4 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 EMR63604.1 - 2.1e-10 40.6 3.4 4.7e-06 26.7 0.0 3.6 4 0 0 4 4 4 2 Cold shock domain Dis3l2_C_term PF17877.1 EMR63604.1 - 0.0034 17.7 0.0 0.0098 16.2 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 EMR63604.1 - 0.053 13.2 0.1 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Trs65 PF12735.7 EMR63605.1 - 2.3e-114 382.1 0.0 3.4e-114 381.5 0.0 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Cwf_Cwc_15 PF04889.12 EMR63605.1 - 0.11 12.2 7.1 0.17 11.6 7.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 EMR63605.1 - 8.7 6.6 8.6 19 5.5 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EMR63605.1 - 9.7 5.4 9.1 15 4.8 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein SIR2 PF02146.17 EMR63606.1 - 1.1e-27 97.1 0.0 2.9e-27 95.7 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.10 EMR63606.1 - 0.16 12.1 1.9 0.3 11.2 1.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Dicty_REP PF05086.12 EMR63606.1 - 2.7 5.8 6.8 3.6 5.5 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_72 PF03198.14 EMR63607.1 - 6e-36 124.3 0.0 7.1e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase DUF3798 PF12683.7 EMR63607.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Cellulase PF00150.18 EMR63607.1 - 0.11 11.9 0.0 0.41 10.0 0.0 1.7 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) CRC_subunit PF08624.10 EMR63608.1 - 6.9e-53 178.7 0.0 9.4e-53 178.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SNF2_N PF00176.23 EMR63609.1 - 2.6e-57 194.1 0.0 5e-57 193.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EMR63609.1 - 3.8e-27 94.0 2.5 1.3e-16 60.2 0.2 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EMR63609.1 - 4.4e-18 65.7 0.0 1.1e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 EMR63609.1 - 6.9e-10 39.2 1.1 1.4e-09 38.2 0.1 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 EMR63609.1 - 9.8e-08 31.5 0.0 3.5e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 EMR63609.1 - 3.7e-06 27.2 1.7 3.7e-06 27.2 1.7 5.0 3 1 1 4 4 4 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 EMR63609.1 - 1.5e-05 25.1 0.0 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 EMR63609.1 - 0.0091 16.0 0.3 0.1 12.6 0.0 2.9 2 1 1 3 3 3 1 SLIDE CDH1_2_SANT_HL1 PF18375.1 EMR63609.1 - 0.016 15.9 1.0 0.15 12.8 1.0 2.9 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 AAA_22 PF13401.6 EMR63609.1 - 0.075 13.3 0.0 0.32 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF2335 PF10097.9 EMR63609.1 - 2.5 8.1 7.7 12 6.0 2.6 3.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) Med16 PF11635.8 EMR63610.1 - 2e-39 135.2 1.1 2.8e-16 58.7 0.0 4.1 2 1 2 4 4 4 4 Mediator complex subunit 16 UvrD_C PF13361.6 EMR63610.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 EMR63611.1 - 2.4e-31 109.1 0.0 6.5e-15 55.8 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 EMR63611.1 - 4.9e-14 51.9 5.7 4.9e-14 51.9 5.7 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 EMR63611.1 - 8.6e-09 35.6 7.8 0.2 11.4 0.0 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMR63611.1 - 1.3e-08 34.6 1.0 0.00032 20.2 0.1 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMR63611.1 - 3.3e-07 30.8 0.0 0.00079 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EMR63611.1 - 8.1e-06 26.1 0.0 0.0018 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.27 EMR63611.1 - 1e-05 25.1 2.7 1e-05 25.1 2.7 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_15 PF13175.6 EMR63611.1 - 1.5e-05 24.9 0.1 0.23 11.1 0.0 2.8 2 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 EMR63611.1 - 1.9e-05 25.1 0.0 0.011 16.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EMR63611.1 - 3.1e-05 24.0 0.1 0.66 9.9 0.0 3.5 4 0 0 4 4 4 2 RsgA GTPase Fer4_10 PF13237.6 EMR63611.1 - 0.00015 21.8 8.6 0.0044 17.1 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_18 PF13238.6 EMR63611.1 - 0.00019 22.0 0.0 0.62 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMR63611.1 - 0.0002 21.0 0.1 0.63 9.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EMR63611.1 - 0.00031 21.3 0.3 0.037 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EMR63611.1 - 0.00048 20.1 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 EMR63611.1 - 0.00063 19.5 0.1 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMR63611.1 - 0.0008 19.4 1.6 0.066 13.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EMR63611.1 - 0.00083 19.7 0.0 0.39 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Fer4_21 PF14697.6 EMR63611.1 - 0.00087 19.4 10.9 0.0018 18.3 10.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 EMR63611.1 - 0.00088 19.0 0.2 1.4 8.6 0.1 3.3 3 0 0 3 3 3 1 Thymidylate kinase NB-ARC PF00931.22 EMR63611.1 - 0.0015 17.8 0.0 0.87 8.7 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Fer4_6 PF12837.7 EMR63611.1 - 0.0016 18.4 12.8 0.0034 17.4 1.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_7 PF12775.7 EMR63611.1 - 0.0018 17.8 0.2 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 EMR63611.1 - 0.0029 17.6 0.1 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EMR63611.1 - 0.0043 17.0 0.2 0.19 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EMR63611.1 - 0.0055 16.4 2.8 0.13 11.9 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_13 PF13166.6 EMR63611.1 - 0.007 15.1 0.0 0.017 13.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMR63611.1 - 0.0073 16.6 0.2 0.96 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMR63611.1 - 0.0082 16.3 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMR63611.1 - 0.0084 15.8 0.2 0.55 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 EMR63611.1 - 0.014 16.0 0.4 0.014 16.0 0.4 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain VirE PF05272.11 EMR63611.1 - 0.04 13.6 0.0 7.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E MMR_HSR1 PF01926.23 EMR63611.1 - 0.057 13.5 0.3 8.9 6.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_9 PF13187.6 EMR63611.1 - 0.069 13.3 10.8 0.15 12.3 10.8 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain PduV-EutP PF10662.9 EMR63611.1 - 0.088 12.6 2.2 0.45 10.2 0.1 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_16 PF13484.6 EMR63611.1 - 0.091 13.7 0.3 0.091 13.7 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain MukB PF04310.12 EMR63611.1 - 0.092 12.5 0.2 9.8 5.9 0.1 2.5 2 0 0 2 2 2 0 MukB N-terminal NTPase_1 PF03266.15 EMR63611.1 - 0.12 12.3 2.9 1.3 8.9 0.2 2.5 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 EMR63611.1 - 0.12 11.9 0.1 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EMR63611.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC MeaB PF03308.16 EMR63611.1 - 0.2 10.6 0.2 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EMR63611.1 - 0.28 11.2 0.8 13 5.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EMR63611.1 - 0.29 10.9 1.4 0.92 9.3 0.1 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_2 PF12797.7 EMR63611.1 - 7.2 6.9 9.6 0.32 11.2 0.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.19 EMR63612.1 - 2.8e-51 171.5 11.3 4.4e-13 49.2 0.1 6.7 6 0 0 6 6 6 6 FF domain WW PF00397.26 EMR63612.1 - 1.6e-17 63.3 19.2 1.7e-10 40.8 5.8 2.7 2 0 0 2 2 2 2 WW domain Ribosomal_60s PF00428.19 EMR63612.1 - 2 9.1 12.6 8.3 7.1 12.6 2.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Glyco_hyd_101C PF17451.2 EMR63612.1 - 2.2 8.6 8.3 12 6.3 0.5 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Rick_17kDa_Anti PF05433.15 EMR63613.1 - 0.036 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF5470 PF17564.2 EMR63613.1 - 0.057 13.6 0.9 0.057 13.6 0.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5470) Abhydrolase_3 PF07859.13 EMR63614.1 - 1.3e-11 44.8 0.0 2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Golgin_A5 PF09787.9 EMR63615.1 - 4.4e-05 23.1 0.4 5.5e-05 22.8 0.4 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 GldM_N PF12081.8 EMR63615.1 - 0.0041 17.2 0.2 0.0053 16.9 0.2 1.2 1 0 0 1 1 1 1 GldM N-terminal domain DUF1043 PF06295.12 EMR63615.1 - 0.0061 16.6 1.1 0.0094 15.9 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Occludin_ELL PF07303.13 EMR63615.1 - 0.0067 17.1 0.5 0.014 16.1 0.5 1.5 1 0 0 1 1 1 1 Occludin homology domain HBM PF16591.5 EMR63615.1 - 0.0087 15.5 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Helical bimodular sensor domain DUF3584 PF12128.8 EMR63615.1 - 0.013 13.1 5.9 0.017 12.7 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 EMR63615.1 - 0.018 15.1 0.3 0.64 10.1 0.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 EMR63615.1 - 0.027 12.4 0.7 0.033 12.1 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 EMR63615.1 - 0.066 11.7 0.5 0.088 11.3 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.8 EMR63615.1 - 0.14 12.2 3.6 0.23 11.6 3.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4208 PF13907.6 EMR63615.1 - 0.19 12.2 2.4 0.32 11.5 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) Plasmid_RAQPRD PF09686.10 EMR63615.1 - 0.2 11.9 0.9 0.61 10.3 0.9 1.9 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF1664 PF07889.12 EMR63615.1 - 0.22 11.5 3.0 0.36 10.9 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EMR63615.1 - 0.3 10.3 2.5 0.37 10.0 2.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 EMR63615.1 - 0.38 9.6 7.6 0.51 9.2 7.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CdvA PF18822.1 EMR63615.1 - 0.52 10.1 6.1 6.3 6.6 2.3 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain BCS1_N PF08740.11 EMR63617.1 - 3.9e-54 183.5 1.6 3.9e-54 183.5 1.6 2.6 2 1 1 3 3 2 1 BCS1 N terminal AAA PF00004.29 EMR63617.1 - 2.5e-16 60.3 0.0 8.9e-08 32.6 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMR63617.1 - 0.00023 21.2 0.0 0.0025 17.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EMR63617.1 - 0.00086 19.2 11.3 0.32 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMR63617.1 - 0.014 15.8 0.1 0.014 15.8 0.1 2.3 2 2 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.6 EMR63617.1 - 0.016 15.5 0.2 0.087 13.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 EMR63617.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_membrane PF00664.23 EMR63617.1 - 0.039 13.6 0.3 0.066 12.8 0.3 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region ATPase PF06745.13 EMR63617.1 - 0.054 12.8 0.2 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 KaiC Macoilin PF09726.9 EMR63617.1 - 0.097 11.2 9.5 0.13 10.7 9.5 1.2 1 0 0 1 1 1 0 Macoilin family DDHD PF02862.17 EMR63617.1 - 0.31 11.2 8.1 21 5.2 10.2 2.3 2 0 0 2 2 2 0 DDHD domain NARP1 PF12569.8 EMR63617.1 - 0.47 9.3 23.9 0.91 8.4 23.9 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2151 PF10221.9 EMR63617.1 - 0.59 8.7 17.7 1.1 7.8 17.7 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator AAA_33 PF13671.6 EMR63617.1 - 1.2 9.3 0.0 1.2 9.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 EMR63617.1 - 3.5 8.1 16.1 6.2 7.3 11.8 2.6 3 0 0 3 3 3 0 AAA domain XRN_M PF17846.1 EMR63617.1 - 3.6 6.4 10.8 5.3 5.9 10.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain U79_P34 PF03064.16 EMR63617.1 - 5.7 6.2 18.2 17 4.7 18.2 1.8 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Mitofilin PF09731.9 EMR63617.1 - 6.1 5.5 28.7 9.3 5.0 28.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cdh1_DBD_1 PF18196.1 EMR63617.1 - 7.9 6.8 0.0 7.9 6.8 0.0 3.6 3 2 1 4 4 3 0 Chromodomain helicase DNA-binding domain 1 Nop14 PF04147.12 EMR63620.1 - 0.21 9.8 20.4 0.27 9.4 20.4 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EMR63620.1 - 0.77 9.1 16.2 0.92 8.9 16.2 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EMR63620.1 - 4 6.1 5.9 4.4 6.0 5.9 1.1 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 EMR63620.1 - 7.5 6.3 14.8 11 5.7 14.8 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein PI3K_1B_p101 PF10486.9 EMR63620.1 - 7.9 4.1 6.3 7.8 4.1 6.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CorA PF01544.18 EMR63621.1 - 0.027 13.8 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HELP PF03451.14 EMR63621.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 HELP motif DUF4212 PF13937.6 EMR63621.1 - 0.14 12.6 0.1 0.2 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) DUF3687 PF12459.8 EMR63621.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein HMG_CoA_synt_C PF08540.10 EMR63622.1 - 1.1e-106 356.5 0.8 1.4e-106 356.2 0.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EMR63622.1 - 4.2e-96 319.8 0.6 6e-96 319.3 0.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal zf-MYND PF01753.18 EMR63623.1 - 2.2e-09 37.3 9.9 5.8e-09 35.9 9.9 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EMR63623.1 - 8.1 6.4 9.6 3.7 7.5 7.2 1.7 2 0 0 2 2 2 0 HIT zinc finger Suc_Fer-like PF06999.12 EMR63624.1 - 2.2e-73 246.3 0.0 2.7e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PfkB PF00294.24 EMR63625.1 - 4.1e-24 85.4 0.0 1.4e-23 83.7 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Epimerase PF01370.21 EMR63627.1 - 1.2e-11 44.5 0.2 2.8e-11 43.3 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMR63627.1 - 0.00013 21.6 0.1 0.00022 20.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EMR63627.1 - 0.00019 20.6 0.1 0.0047 16.0 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EMR63627.1 - 0.00051 20.5 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EMR63627.1 - 0.00058 19.1 0.2 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EMR63627.1 - 0.0027 17.6 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR63627.1 - 0.077 12.4 0.1 0.78 9.1 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_kinase PF01513.21 EMR63628.1 - 1.3e-66 224.8 0.0 8.8e-65 218.8 0.0 2.5 1 1 0 1 1 1 1 ATP-NAD kinase Glyco_hydro_72 PF03198.14 EMR63629.1 - 1.7e-117 392.2 2.6 2.3e-117 391.8 2.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EMR63629.1 - 1.3e-22 80.2 2.1 3.9e-22 78.7 2.1 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EMR63629.1 - 0.0033 16.6 0.2 0.02 14.0 0.2 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cyanate_lyase PF02560.14 EMR63630.1 - 2e-23 82.0 0.0 3.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 EMR63630.1 - 0.0012 18.9 0.1 0.0018 18.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.12 EMR63630.1 - 0.0023 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_31 PF13560.6 EMR63630.1 - 0.022 15.1 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 EMR63630.1 - 0.052 13.1 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 adh_short PF00106.25 EMR63631.1 - 2.7e-36 124.9 0.1 4.5e-36 124.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63631.1 - 5.9e-20 71.8 1.4 6.6e-19 68.4 1.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EMR63631.1 - 0.00011 22.2 2.3 0.0003 20.7 0.5 2.1 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EMR63631.1 - 0.00018 21.5 2.6 0.00038 20.4 1.1 2.2 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 EMR63631.1 - 0.0021 17.6 0.5 0.0036 16.8 0.5 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMR63631.1 - 0.023 13.8 0.2 0.039 13.1 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1402 PF07182.11 EMR63631.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1402) NmrA PF05368.13 EMR63631.1 - 0.046 13.3 0.8 0.14 11.6 0.2 2.0 2 0 0 2 2 2 0 NmrA-like family Radical_SAM_C PF16199.5 EMR63632.1 - 2.7e-32 110.6 0.0 8.3e-32 109.1 0.0 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EMR63632.1 - 5e-17 62.8 0.1 2e-16 60.8 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EMR63632.1 - 8.3e-08 32.5 0.1 1.8e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR63632.1 - 2.7e-06 27.3 0.0 7.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR63632.1 - 0.019 15.4 0.1 0.045 14.2 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UQ_con PF00179.26 EMR63633.1 - 6e-26 90.8 0.0 1.2e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EMR63633.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 UEV domain GFO_IDH_MocA PF01408.22 EMR63634.1 - 1.5e-21 77.4 0.0 2.8e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMR63634.1 - 2.2e-10 40.6 0.0 3.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EMR63634.1 - 0.097 13.3 0.0 0.32 11.7 0.0 1.9 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain MT0933_antitox PF14013.6 EMR63635.1 - 0.65 10.3 8.7 0.74 10.2 5.3 2.7 2 1 0 2 2 2 0 MT0933-like antitoxin protein RNB PF00773.19 EMR63636.1 - 4.8e-75 252.9 0.0 8.1e-75 252.2 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EMR63636.1 - 5e-26 90.5 0.0 1.1e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EMR63636.1 - 1.3e-23 83.1 0.0 4e-23 81.6 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EMR63636.1 - 4.1e-06 26.9 0.0 0.0066 16.6 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EMR63636.1 - 0.049 13.4 0.0 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Rrp44-like cold shock domain Helicase_C PF00271.31 EMR63637.1 - 3.6e-14 53.0 0.2 1.2e-13 51.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMR63637.1 - 3.8e-11 43.2 0.0 1.3e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EMR63637.1 - 2e-10 40.7 0.2 4.3e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 EMR63637.1 - 5e-08 33.2 0.0 1.3e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.6 EMR63637.1 - 1.5e-05 25.3 0.3 5e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EMR63637.1 - 0.00049 20.4 0.0 0.0014 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EMR63637.1 - 0.00095 19.2 0.1 0.0024 17.9 0.1 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 EMR63637.1 - 0.0015 18.5 0.2 0.046 13.7 0.2 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMR63637.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EMR63637.1 - 0.097 12.5 0.2 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Helicase DUF1424 PF07232.11 EMR63637.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative rep protein (DUF1424) AAA_14 PF13173.6 EMR63637.1 - 0.16 12.0 0.2 0.86 9.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain 2-Hacid_dh_C PF02826.19 EMR63638.1 - 1.3e-50 171.2 0.0 1.9e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR63638.1 - 3.8e-16 59.0 0.0 5.6e-16 58.4 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EMR63638.1 - 0.0064 15.8 0.0 0.41 9.9 0.0 2.3 1 1 1 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Amidohydro_2 PF04909.14 EMR63639.1 - 1.7e-42 146.2 0.1 2.1e-42 145.9 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase UQ_con PF00179.26 EMR63640.1 - 5.1e-43 146.1 0.0 6.8e-43 145.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EMR63640.1 - 9.8e-07 28.5 0.6 1.6e-06 27.8 0.6 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF1421 PF07223.11 EMR63640.1 - 0.0097 15.7 0.7 0.13 12.1 0.3 2.3 2 0 0 2 2 2 1 UBA-like domain (DUF1421) Prok-E2_B PF14461.6 EMR63640.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EMR63640.1 - 0.05 13.9 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain ATP-synt_ab PF00006.25 EMR63641.1 - 6.7e-109 362.5 0.0 9.2e-109 362.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EMR63641.1 - 8.5e-48 161.2 0.1 2e-47 160.0 0.1 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EMR63641.1 - 2.2e-14 53.7 4.4 3.9e-14 52.9 2.7 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NAD_kinase PF01513.21 EMR63642.1 - 2.2e-49 168.3 0.0 1.4e-48 165.6 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase TIMELESS PF04821.14 EMR63643.1 - 1.3e-83 280.5 0.2 1.3e-83 280.5 0.2 2.9 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 EMR63643.1 - 5.9e-32 111.6 41.4 5.9e-32 111.6 41.4 3.3 2 1 0 2 2 2 1 Timeless protein C terminal region Acyltransferase PF01553.21 EMR63644.1 - 8.4e-23 80.5 0.0 1.3e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EMR63644.1 - 4.5e-12 45.9 0.3 8e-12 45.1 0.3 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Ank_4 PF13637.6 EMR63645.1 - 0.05 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.7 EMR63646.1 - 6.5e-16 59.6 9.2 1e-15 59.0 9.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR63646.1 - 6.9e-16 58.7 0.2 6.9e-14 52.1 0.2 3.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR63646.1 - 3.4e-11 42.9 1.4 2.2e-10 40.2 1.5 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 TruB_N PF01509.18 EMR63649.1 - 2.4e-44 151.3 0.0 5.1e-44 150.2 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EMR63649.1 - 1.4e-05 25.2 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Nkap_C PF06047.11 EMR63649.1 - 0.092 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain TOM20_plant PF06552.12 EMR63649.1 - 0.12 12.1 0.5 0.22 11.2 0.5 1.4 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 SRP-alpha_N PF04086.13 EMR63649.1 - 3.6 7.4 14.7 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal EXOSC1 PF10447.9 EMR63650.1 - 5e-22 78.6 3.7 3e-14 53.5 0.3 2.8 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 Sec2p PF06428.11 EMR63650.1 - 1.7e-12 47.2 0.5 5.6e-12 45.5 0.8 1.7 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ECR1_N PF14382.6 EMR63650.1 - 2.5e-11 43.2 0.1 4.9e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Jnk-SapK_ap_N PF09744.9 EMR63650.1 - 0.0033 17.6 1.0 0.0056 16.9 1.0 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 HR1 PF02185.16 EMR63650.1 - 0.078 13.1 0.7 0.16 12.1 0.7 1.5 1 0 0 1 1 1 0 Hr1 repeat RNA_polI_A14 PF08203.11 EMR63650.1 - 0.11 13.2 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Cupin_1 PF00190.22 EMR63651.1 - 4e-19 68.7 0.9 6e-19 68.1 0.9 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EMR63651.1 - 0.0046 16.6 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 1 Cupin domain ERG2_Sigma1R PF04622.12 EMR63652.1 - 1.5e-97 325.0 0.0 1.8e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein BSP_II PF05432.11 EMR63653.1 - 0.3 10.8 11.4 0.024 14.4 5.6 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 EMR63653.1 - 0.3 9.2 9.1 0.43 8.7 9.1 1.3 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 EMR63653.1 - 0.49 9.9 4.9 0.88 9.1 4.9 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NOA36 PF06524.12 EMR63653.1 - 0.97 8.7 17.0 1.8 7.8 17.0 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EMR63653.1 - 6.6 4.7 11.7 11 4.0 11.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi Metallophos PF00149.28 EMR63654.1 - 1.5e-14 55.0 0.3 2.5e-14 54.3 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Syntaxin-6_N PF09177.11 EMR63655.1 - 6.3e-26 90.8 0.8 1.9e-25 89.3 0.1 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Pox_EPC_I2-L1 PF12575.8 EMR63655.1 - 0.0025 18.0 0.3 13 6.0 0.0 3.4 3 0 0 3 3 3 1 Poxvirus entry protein complex L1 and I2 Use1 PF09753.9 EMR63655.1 - 0.0056 16.4 2.5 0.014 15.1 2.5 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 EMR63655.1 - 0.037 14.0 0.1 0.037 14.0 0.1 2.4 3 0 0 3 3 3 0 SNARE domain DUF1664 PF07889.12 EMR63655.1 - 0.093 12.8 1.7 2.8 8.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Cwf_Cwc_15 PF04889.12 EMR63655.1 - 0.13 11.9 9.6 0.17 11.6 9.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 EMR63655.1 - 0.15 11.5 0.5 0.26 10.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SURF2 PF05477.11 EMR63655.1 - 0.25 11.0 13.8 0.2 11.3 12.4 1.5 1 1 1 2 2 2 0 Surfeit locus protein 2 (SURF2) TBCA PF02970.16 EMR63655.1 - 0.38 11.1 7.5 0.12 12.7 0.6 3.1 3 1 0 3 3 3 0 Tubulin binding cofactor A DUF3348 PF11828.8 EMR63655.1 - 1.3 8.7 10.2 0.14 11.8 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) RRN3 PF05327.11 EMR63655.1 - 5.5 5.4 5.9 6.8 5.1 5.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ACT_7 PF13840.6 EMR63656.1 - 3.1e-22 78.1 0.3 1.6e-17 63.0 0.0 2.5 2 0 0 2 2 2 2 ACT domain Glyco_hydro_43 PF04616.14 EMR63658.1 - 1.2e-39 136.4 7.1 1.3e-39 136.2 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Methyltransf_32 PF13679.6 EMR63659.1 - 6.4e-24 84.7 0.0 1.2e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DNA_ligase_A_M PF01068.21 EMR63660.1 - 6.2e-15 55.4 0.6 6.3e-10 39.0 0.1 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EMR63660.1 - 0.00089 19.6 0.2 1.2 9.4 0.0 2.5 1 1 1 2 2 2 2 RNA ligase GILT PF03227.16 EMR63660.1 - 0.048 13.9 0.1 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF4048 PF13257.6 EMR63661.1 - 2.8e-19 70.0 23.6 9.2e-19 68.3 15.1 3.4 2 1 2 4 4 4 2 Domain of unknown function (DUF4048) WEMBL PF05701.11 EMR63661.1 - 0.023 13.4 0.2 0.035 12.8 0.2 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light 3HCDH_N PF02737.18 EMR63662.1 - 7e-51 172.7 1.7 1.8e-50 171.3 1.7 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EMR63662.1 - 8.7e-33 112.8 0.0 1.8e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 EMR63662.1 - 4.7e-05 23.7 0.2 0.00011 22.5 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EMR63662.1 - 0.00032 20.9 0.9 0.00096 19.4 0.9 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 EMR63662.1 - 0.006 16.2 0.1 0.0075 15.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 EMR63662.1 - 0.025 14.2 0.4 0.088 12.5 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EMR63662.1 - 0.029 13.7 0.2 0.062 12.6 0.2 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_channel_TID PF07941.11 EMR63662.1 - 0.25 11.8 2.9 7.4 7.1 1.2 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain F420_oxidored PF03807.17 EMR63662.1 - 0.45 11.1 3.0 3.7 8.2 2.7 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ATG22 PF11700.8 EMR63663.1 - 3.5e-124 415.1 21.7 4.1e-124 414.8 21.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SHOCT PF09851.9 EMR63663.1 - 0.11 12.3 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Short C-terminal domain GLE1 PF07817.13 EMR63665.1 - 2.9e-49 167.5 0.0 3.7e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 GLE1-like protein NUDIX PF00293.28 EMR63666.1 - 2.7e-13 50.1 0.1 4.1e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Ferritin_2 PF13668.6 EMR63667.1 - 9.4e-39 132.7 0.2 1.7e-38 131.9 0.2 1.4 1 0 0 1 1 1 1 Ferritin-like domain PP2C PF00481.21 EMR63668.1 - 1.3e-60 205.3 0.5 2.1e-49 168.5 0.1 3.9 2 1 1 3 3 3 2 Protein phosphatase 2C Cation_efflux PF01545.21 EMR63669.1 - 1.7e-23 83.4 4.2 2.1e-23 83.1 4.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMR63669.1 - 0.033 14.3 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter p450 PF00067.22 EMR63670.1 - 1.7e-31 109.5 0.0 2.3e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.6 EMR63671.1 - 2.5e-08 33.9 0.0 7e-08 32.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR63671.1 - 3.8e-08 33.4 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR63671.1 - 1.9e-07 31.7 0.0 4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR63671.1 - 3.6e-05 24.4 0.0 7.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR63671.1 - 0.01 16.5 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EMR63671.1 - 0.013 15.6 0.0 0.1 12.7 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 EMR63671.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Snf7 PF03357.21 EMR63672.1 - 5e-34 117.4 19.0 5e-34 117.4 19.0 1.4 1 1 1 2 2 2 1 Snf7 CaMBD PF02888.16 EMR63672.1 - 0.031 14.5 0.9 0.031 14.5 0.9 2.2 3 0 0 3 3 3 0 Calmodulin binding domain LdpA_C PF12617.8 EMR63672.1 - 0.069 12.8 0.8 0.14 11.8 0.3 1.7 1 1 0 1 1 1 0 Iron-Sulfur binding protein C terminal RHH_8 PF17723.1 EMR63672.1 - 0.077 13.2 3.8 0.19 11.9 0.1 2.3 1 1 1 2 2 2 0 Ribbon-Helix-Helix transcriptional regulator family Ist1 PF03398.14 EMR63672.1 - 0.19 11.6 7.2 0.33 10.9 7.2 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YojJ PF10372.9 EMR63672.1 - 8.5 6.6 7.2 1.9 8.7 0.2 2.9 3 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus adh_short PF00106.25 EMR63673.1 - 8.4e-22 77.6 0.1 5.8e-20 71.6 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63673.1 - 7.2e-10 38.8 0.3 0.00049 19.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR63673.1 - 0.0019 17.7 0.1 0.22 10.9 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR63673.1 - 0.0024 17.8 1.6 0.0069 16.3 1.5 1.8 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMR63673.1 - 0.025 14.5 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.17 EMR63673.1 - 0.065 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NACHT PF05729.12 EMR63674.1 - 6.1e-09 36.0 0.1 1.8e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.7 EMR63674.1 - 8.4e-09 35.9 0.2 8.8e-08 32.6 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR63674.1 - 2.1e-08 34.5 0.1 3.4e-07 30.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR63674.1 - 2.1e-07 31.1 0.0 5.9e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NB-ARC PF00931.22 EMR63674.1 - 3.9e-07 29.5 0.1 1.7e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 NB-ARC domain Ank PF00023.30 EMR63674.1 - 1.4e-06 28.4 2.9 0.00083 19.7 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat AAA_16 PF13191.6 EMR63674.1 - 0.00012 22.5 0.0 0.00093 19.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.6 EMR63674.1 - 0.0012 19.2 0.2 0.015 15.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Helo_like_N PF17111.5 EMR63674.1 - 0.0088 15.4 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA PF00004.29 EMR63674.1 - 0.011 16.2 0.0 0.16 12.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMR63674.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 EMR63674.1 - 0.053 13.8 0.0 0.31 11.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.12 EMR63674.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SelK_SelG PF10961.8 EMR63676.1 - 0.0029 18.2 1.1 0.007 17.0 1.1 1.6 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Adeno_PIX PF03955.14 EMR63676.1 - 0.074 13.2 2.5 0.15 12.2 1.9 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) OPT PF03169.15 EMR63677.1 - 9.7e-09 34.4 1.1 1e-08 34.3 1.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein peroxidase PF00141.23 EMR63678.1 - 8.5e-29 100.9 3.0 3.9e-28 98.7 3.0 1.8 1 1 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 EMR63678.1 - 4e-05 23.5 0.0 9.2e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region DUF640 PF04852.12 EMR63679.1 - 0.077 13.2 0.5 0.16 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF640) DUF676 PF05057.14 EMR63680.1 - 3.9e-45 154.0 0.0 7.4e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EMR63680.1 - 0.0023 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EMR63680.1 - 0.0075 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EMR63680.1 - 0.017 15.7 0.2 0.041 14.5 0.1 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EMR63680.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF4536 PF15055.6 EMR63681.1 - 3.6e-07 30.3 2.4 5.4e-07 29.8 2.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) SPT16 PF08644.11 EMR63682.1 - 2.4e-55 186.9 0.2 2.4e-55 186.9 0.2 3.3 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EMR63682.1 - 1.7e-54 184.0 1.5 1.7e-54 184.0 1.5 2.2 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EMR63682.1 - 2.3e-25 89.6 0.0 4.1e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EMR63682.1 - 2.4e-16 59.9 0.3 9.6e-16 58.0 0.0 2.2 3 0 0 3 3 3 1 Histone chaperone Rttp106-like TPR_12 PF13424.6 EMR63683.1 - 5.4e-08 33.0 2.5 8.2e-05 22.8 0.8 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMR63683.1 - 0.00042 20.1 1.2 0.0082 16.0 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat MARVEL PF01284.23 EMR63684.1 - 1.9e-22 79.8 15.3 2.2e-22 79.6 15.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.11 EMR63684.1 - 0.053 13.6 4.1 0.075 13.1 1.9 2.2 2 1 0 2 2 2 0 M penetrans paralogue family 26 HhH-GPD PF00730.25 EMR63685.1 - 3e-17 63.0 0.0 5.5e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EMR63685.1 - 2.1e-08 33.6 0.0 4.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPATIAL PF15256.6 EMR63685.1 - 0.0059 17.0 4.9 0.0068 16.8 3.6 1.8 2 0 0 2 2 2 1 SPATIAL ApbE PF02424.15 EMR63685.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 ApbE family SUR7 PF06687.12 EMR63686.1 - 3.3e-21 75.9 5.2 3.3e-21 75.9 5.2 1.4 1 1 0 1 1 1 1 SUR7/PalI family LYRIC PF15686.5 EMR63686.1 - 0.029 14.0 2.7 1.1 8.7 0.5 2.1 1 1 1 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family Trp_oprn_chp PF09534.10 EMR63686.1 - 0.046 13.5 9.8 0.087 12.6 7.2 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 EMR63686.1 - 0.22 12.4 0.9 28 5.7 0.0 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2371 PF10177.9 EMR63686.1 - 0.44 10.7 2.1 0.47 10.6 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Phage_holin_3_6 PF07332.11 EMR63686.1 - 0.73 9.9 19.1 0.42 10.7 7.7 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 EMR63686.1 - 0.98 8.1 6.0 10 4.8 5.5 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PIG-Y PF15159.6 EMR63686.1 - 5.6 8.0 6.4 99 4.0 0.1 3.4 3 1 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Sensor PF13796.6 EMR63686.1 - 9.1 6.3 21.4 2.7 8.0 10.5 2.9 3 0 0 3 3 3 0 Putative sensor Macoilin PF09726.9 EMR63687.1 - 0.0016 17.1 0.3 0.0019 16.9 0.3 1.4 1 0 0 1 1 1 1 Macoilin family SOG2 PF10428.9 EMR63687.1 - 8.3 5.5 22.6 12 4.9 22.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4267 PF14087.6 EMR63688.1 - 2.2e-16 59.9 0.6 2.9e-16 59.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Pkinase PF00069.25 EMR63689.1 - 1.6e-28 99.8 2.3 2.1e-28 99.4 2.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR63689.1 - 6.9e-16 58.3 0.6 8.9e-16 57.9 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMR63689.1 - 0.0023 17.9 0.0 0.0072 16.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMR63689.1 - 0.0034 17.0 0.8 0.0078 15.8 0.7 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EMR63689.1 - 0.026 14.1 0.1 0.045 13.4 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 EMR63689.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_N PF08240.12 EMR63690.1 - 4.7e-23 81.2 3.3 8.1e-23 80.4 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR63690.1 - 9.1e-18 64.5 0.2 1.8e-17 63.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMR63690.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 EMR63690.1 - 0.15 11.8 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain TPR_2 PF07719.17 EMR63692.1 - 3.1e-05 23.8 0.0 2.1 8.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMR63692.1 - 0.00011 21.9 0.1 0.67 9.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMR63692.1 - 0.0027 18.0 0.0 0.45 10.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMR63692.1 - 0.044 14.6 0.0 1.3 10.0 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMR63692.1 - 0.046 13.9 0.2 21 5.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EMR63692.1 - 0.049 13.6 2.4 0.53 10.3 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMR63692.1 - 0.057 14.1 1.2 3.5 8.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMR63692.1 - 0.088 12.5 0.1 8.1 6.2 0.0 2.6 3 0 0 3 3 3 0 TPR repeat SGL PF08450.12 EMR63693.1 - 6.5e-05 22.6 0.1 0.017 14.7 0.0 3.0 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 EMR63693.1 - 0.00067 19.6 0.0 1.6 8.8 0.0 2.8 2 0 0 2 2 2 2 Beta-propeller repeat GSDH PF07995.11 EMR63693.1 - 0.0072 15.7 0.6 0.061 12.6 0.7 2.5 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 EMR63693.1 - 0.027 14.5 0.0 26 5.1 0.0 4.0 3 0 0 3 3 3 0 NHL repeat Glyco_hydro_43 PF04616.14 EMR63694.1 - 1.6e-60 204.9 3.0 2e-60 204.6 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EMR63694.1 - 6e-16 58.8 0.0 1.9e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain SDA1 PF05285.12 EMR63695.1 - 0.046 13.1 21.2 0.075 12.5 14.5 2.1 2 0 0 2 2 2 0 SDA1 SOCS PF12610.8 EMR63695.1 - 0.99 9.9 6.0 2.2 8.8 0.0 2.9 2 0 0 2 2 2 0 Suppressor of cytokine signalling Apt1 PF10351.9 EMR63695.1 - 3.1 6.5 9.8 0.035 13.0 2.0 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain GRDP-like PF07173.12 EMR63695.1 - 5.1 7.7 9.0 1.5 9.4 1.7 3.1 4 0 0 4 4 4 0 Glycine-rich domain-containing protein-like BBE PF08031.12 EMR63696.1 - 0.0012 18.9 0.4 0.0024 17.9 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Caps_synth PF05704.12 EMR63697.1 - 3.1e-19 69.4 0.8 4.9e-19 68.8 0.8 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 EMR63697.1 - 5.9e-05 23.6 0.0 0.00012 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif GHMP_kinases_N PF00288.26 EMR63698.1 - 2.4e-16 59.7 1.7 2.4e-16 59.7 1.7 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMR63698.1 - 1.1e-06 28.9 0.1 3.9e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal Pkinase PF00069.25 EMR63699.1 - 6.4e-18 65.1 0.0 1.6e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR63699.1 - 6.2e-12 45.4 0.0 2.8e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EMR63699.1 - 0.041 12.9 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase 7tm_6 PF02949.20 EMR63699.1 - 0.21 10.6 0.1 0.34 9.9 0.1 1.3 1 0 0 1 1 1 0 7tm Odorant receptor MCM PF00493.23 EMR63700.1 - 1.5e-102 341.4 1.0 2.2e-102 340.9 0.4 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EMR63700.1 - 9.2e-38 128.9 0.1 1.6e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EMR63700.1 - 1.9e-32 111.7 0.0 5.5e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EMR63700.1 - 1.8e-24 86.0 0.1 6.5e-24 84.2 0.1 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMR63700.1 - 1.3e-15 57.8 0.4 7.8e-15 55.3 0.0 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMR63700.1 - 9.2e-08 31.7 0.0 1.1e-06 28.2 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EMR63700.1 - 0.00039 20.3 0.3 0.0038 17.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMR63700.1 - 0.00041 20.1 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EMR63700.1 - 0.027 14.4 0.0 0.076 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM_bind PF09739.9 EMR63700.1 - 0.13 10.6 0.8 0.25 9.8 0.0 1.8 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor GIDA_assoc PF13932.6 EMR63700.1 - 0.31 11.2 2.3 0.25 11.5 0.5 1.8 2 0 0 2 2 2 0 GidA associated domain CCDC53 PF10152.9 EMR63700.1 - 1.4 9.3 4.4 0.53 10.7 0.4 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex AA_permease PF00324.21 EMR63701.1 - 6.6e-13 48.1 3.3 8.3e-13 47.7 3.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.21 EMR63702.1 - 3.4e-08 33.1 0.0 3.8e-06 26.3 0.0 3.2 2 1 0 2 2 2 1 Aminotransferase class I and II MOZ_SAS PF01853.18 EMR63703.1 - 1.5e-80 269.1 0.3 2.2e-80 268.6 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EMR63703.1 - 9e-23 79.7 2.8 1.9e-22 78.6 2.8 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EMR63703.1 - 5e-16 58.3 0.0 1.5e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EMR63703.1 - 0.00083 19.7 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR63703.1 - 0.035 14.3 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pox_Ag35 PF03286.14 EMR63703.1 - 4.5 7.0 8.0 0.63 9.8 3.5 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Adenylsucc_synt PF00709.21 EMR63704.1 - 6.4e-83 279.0 0.1 7.1e-72 242.6 0.0 2.7 2 1 1 3 3 3 2 Adenylosuccinate synthetase RNase_T PF00929.24 EMR63704.1 - 1.2e-15 58.5 0.0 2.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease KHA PF11834.8 EMR63704.1 - 0.095 12.8 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel RNase_H2_suC PF08615.11 EMR63705.1 - 2.2e-08 34.4 0.0 2.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ferric_reduct PF01794.19 EMR63706.1 - 7.9e-24 84.2 14.9 7.9e-24 84.2 14.9 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMR63706.1 - 6.5e-12 45.8 0.0 1.1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR63706.1 - 1.2e-10 41.4 0.0 1.3e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EMR63706.1 - 0.013 16.1 0.0 0.73 10.5 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Ribosomal_60s PF00428.19 EMR63706.1 - 0.021 15.4 2.7 0.048 14.2 2.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop53 PF07767.11 EMR63707.1 - 1.2e-107 360.8 30.2 1.4e-107 360.6 30.2 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF16 PF01519.16 EMR63707.1 - 1.7 9.2 7.1 3 8.4 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 EthD PF07110.11 EMR63708.1 - 2.6e-09 38.1 0.5 3.7e-09 37.6 0.5 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EMR63708.1 - 4e-07 30.5 0.0 4.6e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase TFIIA PF03153.13 EMR63709.1 - 9.8 6.0 24.6 12 5.7 24.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTK PF00779.19 EMR63710.1 - 0.0054 16.5 5.3 0.012 15.4 5.3 1.7 1 0 0 1 1 1 1 BTK motif Ras PF00071.22 EMR63712.1 - 5.5e-42 143.1 0.1 7.5e-42 142.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR63712.1 - 2.9e-21 75.9 0.1 7e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR63712.1 - 8.8e-12 44.8 0.5 1.2e-11 44.4 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMR63712.1 - 1.1e-05 25.1 0.1 2.1e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FlgH PF02107.16 EMR63712.1 - 0.013 15.1 1.5 0.02 14.5 1.5 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein Gtr1_RagA PF04670.12 EMR63712.1 - 0.02 14.3 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TIR_2 PF13676.6 EMR63712.1 - 0.028 15.0 0.1 0.039 14.6 0.1 1.5 1 1 0 1 1 1 0 TIR domain ATP_bind_1 PF03029.17 EMR63712.1 - 0.038 13.8 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TetR_C_16 PF17920.1 EMR63712.1 - 0.049 13.9 0.0 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain zf-rbx1 PF12678.7 EMR63713.1 - 1.8e-06 28.1 1.4 1.8e-06 28.1 1.4 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EMR63713.1 - 2e-06 28.0 4.9 2e-06 28.0 4.9 3.5 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMR63713.1 - 5e-06 26.3 7.2 5.4e-05 23.0 1.4 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR63713.1 - 3e-05 24.0 0.8 3e-05 24.0 0.8 3.2 3 1 1 4 4 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMR63713.1 - 0.00046 20.1 1.1 0.00046 20.1 1.1 2.8 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EMR63713.1 - 0.00062 19.6 0.2 0.00062 19.6 0.2 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMR63713.1 - 0.0023 17.8 3.9 0.0099 15.7 0.5 2.8 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EMR63713.1 - 0.0041 17.2 0.1 0.0041 17.2 0.1 3.2 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zinc_ribbon_9 PF14369.6 EMR63713.1 - 0.0061 16.8 2.0 2.4 8.5 0.3 2.8 2 0 0 2 2 2 2 zinc-ribbon zf-ANAPC11 PF12861.7 EMR63713.1 - 0.0067 16.5 5.8 0.021 14.9 2.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SelK_SelG PF10961.8 EMR63713.1 - 0.054 14.1 0.7 0.1 13.2 0.7 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG zf-C3HC4_2 PF13923.6 EMR63713.1 - 0.054 13.3 0.8 0.054 13.3 0.8 3.9 5 1 0 5 5 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EMR63713.1 - 0.15 11.9 5.9 4.3 7.2 0.4 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EMR63713.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.8 4 0 0 4 4 4 0 RING-like zinc finger Pellino PF04710.14 EMR63713.1 - 0.55 8.8 2.0 0.56 8.8 0.3 1.7 2 0 0 2 2 2 0 Pellino zinc-ribbons_6 PF07191.12 EMR63713.1 - 1.3 9.1 5.6 9 6.4 0.6 2.8 3 0 0 3 3 3 0 zinc-ribbons HET PF06985.11 EMR63714.1 - 0.081 13.3 0.2 0.26 11.6 0.2 1.9 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 EMR63716.1 - 2.5e-16 59.6 26.3 3.1e-16 59.2 26.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily COX2-transmemb PF09125.10 EMR63717.1 - 8.7 6.2 7.6 2.7 7.9 0.4 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane ETC_C1_NDUFA4 PF04800.12 EMR63718.1 - 2.8e-36 123.6 0.5 4e-36 123.2 0.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 EMR63719.1 - 6.6e-39 132.3 0.3 7.5e-39 132.1 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi FAD_binding_3 PF01494.19 EMR63720.1 - 2.3e-06 27.1 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR63720.1 - 0.002 18.3 0.0 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMR63720.1 - 0.024 15.2 0.3 0.15 12.7 0.1 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR63720.1 - 0.047 13.3 1.1 0.11 12.1 0.8 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR63720.1 - 0.065 13.2 0.0 0.85 9.6 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMR63720.1 - 0.14 11.3 0.2 0.31 10.2 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DIT1_PvcA PF05141.12 EMR63721.1 - 8.8e-96 320.6 0.0 1.1e-95 320.3 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein PAP_assoc PF03828.19 EMR63722.1 - 1.7e-18 66.6 0.1 7.8e-17 61.3 0.1 2.7 1 1 0 1 1 1 1 Cid1 family poly A polymerase Retrotrans_gag PF03732.17 EMR63722.1 - 1.5e-06 28.4 0.1 0.016 15.5 0.1 2.8 2 0 0 2 2 2 2 Retrotransposon gag protein NTP_transf_2 PF01909.23 EMR63722.1 - 0.0011 19.2 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain RAP1 PF07218.11 EMR63723.1 - 1.5 7.1 9.8 1.9 6.7 9.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) p450 PF00067.22 EMR63724.1 - 5.7e-55 186.9 0.0 5.9e-54 183.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Cu-oxidase PF00394.22 EMR63725.1 - 4.2e-33 114.7 0.0 6.4e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMR63725.1 - 3.6e-18 65.6 1.0 5.9e-17 61.7 2.5 2.2 2 1 0 2 2 2 1 Multicopper oxidase WSC PF01822.19 EMR63726.1 - 9.1e-70 230.9 63.6 3.1e-19 69.0 13.4 4.1 4 0 0 4 4 4 4 WSC domain Cytomega_gL PF01801.16 EMR63726.1 - 0.75 9.1 1.9 18 4.6 0.0 2.9 3 0 0 3 3 3 0 Cytomegalovirus glycoprotein L Toxin_35 PF10530.9 EMR63726.1 - 1.3 9.0 21.0 4.3 7.4 0.5 4.6 4 0 0 4 4 4 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold NIR_SIR PF01077.22 EMR63728.1 - 2.5e-53 179.9 0.1 1e-48 164.9 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 EMR63728.1 - 4e-30 104.9 0.0 8.6e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 EMR63728.1 - 1.5e-29 101.6 0.1 3.3e-14 52.5 0.1 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 EMR63728.1 - 3.6e-09 36.7 0.1 1e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg UPRTase PF14681.6 EMR63729.1 - 5e-34 117.6 0.0 7.5e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_11 PF08241.12 EMR63730.1 - 1.9e-09 38.0 0.0 3.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR63730.1 - 2e-06 28.4 0.0 4.5e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR63730.1 - 0.038 13.3 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EMR63730.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EMR63731.1 - 0.024 15.3 0.0 0.044 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EMR63731.1 - 0.11 13.3 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ABM PF03992.16 EMR63732.1 - 0.00016 21.7 0.1 0.00021 21.3 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Spo0M PF07070.11 EMR63732.1 - 0.035 13.7 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 SpoOM protein Rib_5-P_isom_A PF06026.14 EMR63733.1 - 1.5e-45 154.9 0.0 2.4e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) FAD_binding_3 PF01494.19 EMR63734.1 - 2.2e-61 208.1 0.0 3.3e-61 207.5 0.0 1.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EMR63734.1 - 1.8e-06 27.3 1.6 2.9e-05 23.3 1.6 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EMR63734.1 - 8.9e-06 24.7 0.3 0.0005 18.9 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EMR63734.1 - 1.8e-05 24.2 2.8 0.03 13.6 1.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR63734.1 - 4.8e-05 22.7 0.2 0.0054 16.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR63734.1 - 0.00042 20.0 0.6 0.025 14.2 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR63734.1 - 0.0015 18.7 0.2 0.0052 17.0 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMR63734.1 - 0.0048 17.4 0.1 0.097 13.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR63734.1 - 0.0058 16.0 0.5 0.019 14.3 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMR63734.1 - 0.026 13.8 0.1 0.072 12.4 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EMR63734.1 - 0.037 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EMR63734.1 - 0.055 12.5 0.2 0.1 11.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 EMR63734.1 - 0.06 12.6 0.1 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pantoate_ligase PF02569.15 EMR63735.1 - 9.4e-92 307.0 0.0 1.1e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase TENA_THI-4 PF03070.16 EMR63736.1 - 3e-05 24.0 2.7 0.005 16.7 0.4 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Bud13 PF09736.9 EMR63737.1 - 3.1e-43 147.7 3.0 3.1e-43 147.7 3.0 2.4 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF4010 PF13194.6 EMR63737.1 - 0.25 11.0 2.6 0.15 11.7 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Pyr_redox_2 PF07992.14 EMR63738.1 - 4.5e-42 144.3 0.0 6.5e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR63738.1 - 4.4e-12 46.4 0.0 4.3e-10 40.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EMR63738.1 - 1e-06 27.9 0.5 2.2e-06 26.8 0.5 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EMR63738.1 - 5.1e-05 22.9 0.8 0.00016 21.4 0.8 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EMR63738.1 - 0.00077 19.9 0.2 0.0018 18.7 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EMR63738.1 - 0.0015 18.0 1.6 0.0033 16.9 1.6 1.5 1 0 0 1 1 1 1 EF hand FAD_binding_2 PF00890.24 EMR63738.1 - 0.056 12.5 0.0 1.2 8.1 0.1 2.7 3 0 0 3 3 3 0 FAD binding domain bVLRF1 PF18826.1 EMR63738.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor Methyltransf_23 PF13489.6 EMR63739.1 - 0.0014 18.5 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HET PF06985.11 EMR63740.1 - 5e-29 101.5 6.7 5e-29 101.5 6.7 3.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ORC6 PF05460.13 EMR63740.1 - 0.0047 16.3 12.0 0.0073 15.6 12.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF572 PF04502.13 EMR63740.1 - 0.0069 16.1 7.5 0.011 15.4 7.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) PPL5 PF18168.1 EMR63740.1 - 1.4 8.2 4.6 2.2 7.5 4.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 PI3K_1B_p101 PF10486.9 EMR63740.1 - 1.7 6.3 11.2 2.5 5.7 11.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 EMR63740.1 - 2.1 7.0 11.0 3.3 6.4 11.0 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EMR63740.1 - 2.4 7.3 3.8 4 6.6 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 EMR63740.1 - 3.5 6.3 9.9 6.7 5.4 9.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Smg8_Smg9 PF10220.9 EMR63740.1 - 4 5.6 11.0 5.9 5.1 11.0 1.2 1 0 0 1 1 1 0 Smg8_Smg9 SR-25 PF10500.9 EMR63740.1 - 6.5 6.3 29.0 32 4.0 24.0 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein RP-C_C PF11800.8 EMR63740.1 - 8.7 6.4 7.9 16 5.5 7.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region MFS_1 PF07690.16 EMR63741.1 - 3.8e-29 101.7 45.0 1.1e-27 96.9 45.0 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR63741.1 - 2.9e-11 42.9 2.2 2.9e-11 42.9 2.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMR63741.1 - 6e-06 25.0 20.6 1.4e-05 23.8 20.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EMR63741.1 - 0.00082 18.3 6.6 0.00082 18.3 6.6 2.3 2 1 0 2 2 2 1 MFS_1 like family TP_methylase PF00590.20 EMR63742.1 - 4.8e-22 78.9 0.1 7.6e-22 78.3 0.1 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases V-ATPase_H_N PF03224.14 EMR63743.1 - 0.069 12.4 0.2 0.28 10.4 0.1 1.8 2 0 0 2 2 2 0 V-ATPase subunit H Glyco_transf_90 PF05686.12 EMR63744.1 - 3.9e-12 45.8 0.1 4.9e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 90 DUF809 PF05663.11 EMR63744.1 - 0.0011 19.1 4.7 0.002 18.3 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF809) Coatomer_WDAD PF04053.14 EMR63745.1 - 1.9e-170 567.7 0.0 6.8e-170 565.9 0.0 1.8 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EMR63745.1 - 1.5e-37 126.9 6.5 4.7e-06 27.2 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR63745.1 - 9.2e-07 29.1 0.0 4.4 7.7 0.0 5.9 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR63745.1 - 2.6e-05 23.1 0.9 0.038 12.7 0.1 3.4 1 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EMR63745.1 - 0.0066 16.5 0.0 5.2 7.2 0.0 4.0 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.25 EMR63746.1 - 1.8e-70 237.3 0.0 2.3e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR63746.1 - 2.1e-33 115.7 0.0 2.8e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EMR63746.1 - 4.2e-12 46.6 1.1 1.3e-11 45.0 1.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EMR63746.1 - 1.6e-06 27.3 0.0 2.3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 EMR63746.1 - 0.0097 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EMR63746.1 - 0.012 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EMR63746.1 - 0.09 12.4 0.1 0.9 9.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EMR63746.1 - 0.18 11.2 0.1 0.34 10.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 EMR63747.1 - 2.2e-15 56.7 0.0 4.6e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain RGS PF00615.19 EMR63747.1 - 5.1e-11 42.9 0.0 9.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_4 PF08448.10 EMR63747.1 - 1.4e-07 31.7 0.0 2.5e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 EMR63747.1 - 0.012 15.9 0.0 0.044 14.1 0.0 2.0 1 1 0 1 1 1 0 PAS fold PAS PF00989.25 EMR63747.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.8 1 1 0 1 1 1 0 PAS fold AhpC-TSA PF00578.21 EMR63748.1 - 5.6e-38 129.7 0.0 7.6e-38 129.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMR63748.1 - 6.6e-13 48.6 0.0 9.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EMR63748.1 - 4.7e-12 45.6 0.0 8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin adh_short_C2 PF13561.6 EMR63749.1 - 1.4e-40 139.3 0.1 2e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR63749.1 - 1.7e-31 109.2 0.0 1.3e-30 106.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMR63749.1 - 0.0013 18.7 0.1 0.0023 17.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Pyrid_ox_like PF16242.5 EMR63751.1 - 2.4e-23 82.4 0.0 3.6e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EMR63751.1 - 2.4e-09 37.2 0.0 4.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Hva1_TUDOR PF11160.8 EMR63751.1 - 0.12 12.6 0.6 0.91 9.7 0.0 2.6 3 0 0 3 3 3 0 Hypervirulence associated proteins TUDOR domain Mannitol_dh_C PF08125.13 EMR63752.1 - 1.1e-41 143.0 0.1 1.6e-41 142.4 0.1 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EMR63752.1 - 9.4e-22 77.8 1.4 3.9e-21 75.8 0.0 2.4 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain PGI PF00342.19 EMR63753.1 - 1.7e-131 439.2 0.5 1.9e-131 439.0 0.5 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase zf-C2H2_jaz PF12171.8 EMR63754.1 - 3.3e-07 30.4 0.1 5.7e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMR63754.1 - 2.5e-05 24.5 0.1 4.3e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 EMR63754.1 - 0.0006 19.8 0.4 0.0013 18.8 0.4 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 EMR63754.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 DBF zinc finger TFIIB PF00382.19 EMR63755.1 - 1.1e-38 131.1 2.6 1.2e-24 86.1 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EMR63755.1 - 2.9e-14 52.3 0.8 4.6e-14 51.7 0.8 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 EMR63755.1 - 0.00051 20.1 0.0 0.078 13.1 0.0 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain RB_B PF01857.20 EMR63755.1 - 0.00055 20.0 0.1 0.00096 19.2 0.1 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain TMIE PF16038.5 EMR63755.1 - 0.059 13.2 0.1 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 TMIE protein zf-ribbon_3 PF13248.6 EMR63755.1 - 0.089 12.2 1.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HTH_5 PF01022.20 EMR63755.1 - 0.15 12.0 0.0 26 4.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family PHD PF00628.29 EMR63756.1 - 8.7e-09 35.1 10.0 1.4e-08 34.5 10.0 1.3 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EMR63756.1 - 0.0057 16.5 5.1 0.0057 16.5 5.1 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EMR63756.1 - 0.022 14.4 5.0 0.047 13.3 5.0 1.6 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 EMR63756.1 - 0.14 12.1 5.4 0.29 11.1 5.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.16 EMR63756.1 - 0.31 11.3 5.5 0.53 10.5 5.5 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.6 EMR63756.1 - 0.72 9.5 14.8 0.12 11.9 10.0 2.2 2 1 0 2 2 2 0 PHD-finger GvpL_GvpF PF06386.11 EMR63757.1 - 0.11 12.4 17.4 0.17 11.8 17.4 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Miga PF10265.9 EMR63757.1 - 1.1 8.2 8.6 1.4 7.8 8.6 1.1 1 0 0 1 1 1 0 Mitoguardin MDM10 PF12519.8 EMR63757.1 - 3.2 6.5 7.7 4 6.2 7.7 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DDHD PF02862.17 EMR63757.1 - 3.9 7.6 7.7 5.6 7.1 7.7 1.2 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 EMR63757.1 - 5.7 6.8 22.3 7.2 6.5 22.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 EMR63757.1 - 7.3 5.4 36.5 9.5 5.1 36.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 GMC_oxred_C PF05199.13 EMR63758.1 - 1.6e-09 38.5 0.0 2.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR63758.1 - 3e-08 33.4 0.1 7.3e-08 32.1 0.1 1.6 2 0 0 2 2 2 1 GMC oxidoreductase CoA_transf_3 PF02515.17 EMR63759.1 - 1.1e-113 380.1 0.0 1.3e-113 379.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III AA_permease_2 PF13520.6 EMR63760.1 - 6.3e-50 170.2 44.0 7.4e-50 170.0 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR63760.1 - 5.5e-26 91.2 39.4 7.5e-26 90.7 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1356 PF07092.12 EMR63760.1 - 0.5 9.6 1.2 0.89 8.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) UPF0203 PF05254.12 EMR63761.1 - 2 8.7 7.3 0.64 10.3 0.2 2.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) NARP1 PF12569.8 EMR63762.1 - 2e-192 640.7 19.4 8.9e-192 638.6 9.6 2.5 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 EMR63762.1 - 3.1e-21 75.7 16.0 6.4e-05 23.5 1.5 8.6 7 2 1 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMR63762.1 - 2.3e-19 69.6 30.6 0.0026 18.2 0.0 7.9 8 1 0 8 8 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMR63762.1 - 1.4e-15 56.6 18.6 0.0046 17.7 0.1 9.6 6 3 3 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 EMR63762.1 - 4.5e-13 49.1 13.7 0.00019 21.5 0.6 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMR63762.1 - 4.7e-13 48.2 39.4 4.5e-05 23.2 0.2 11.4 12 1 0 12 12 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMR63762.1 - 3.5e-10 39.4 14.2 3.6e-05 23.3 0.1 5.5 6 0 0 6 6 6 3 TPR repeat TPR_1 PF00515.28 EMR63762.1 - 5.9e-10 38.5 26.2 4.1e-06 26.4 0.4 8.6 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMR63762.1 - 2.7e-08 34.0 20.2 0.15 12.3 0.1 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMR63762.1 - 1.5e-07 31.1 18.9 0.00064 19.7 0.1 7.6 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EMR63762.1 - 1.4e-06 27.8 19.6 0.0089 15.3 2.9 5.4 3 1 2 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR63762.1 - 3.2e-06 27.3 20.5 0.0022 18.2 1.7 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EMR63762.1 - 8.7e-06 25.8 21.7 0.63 10.5 0.0 9.6 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMR63762.1 - 0.00016 21.5 8.1 6.3 7.1 0.2 7.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMR63762.1 - 0.00022 21.2 12.4 2.1 8.5 0.3 5.4 5 0 0 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 EMR63762.1 - 0.045 14.2 0.1 0.045 14.2 0.1 3.4 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TPR_3 PF07720.12 EMR63762.1 - 0.052 13.6 3.9 0.19 11.8 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR63762.1 - 0.064 13.9 12.7 0.94 10.3 0.4 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EMR63762.1 - 0.31 10.7 5.1 10 5.8 0.0 4.7 5 1 0 6 6 6 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 EMR63762.1 - 1 9.4 16.4 7.7 6.5 0.1 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat zf-GRF PF06839.12 EMR63763.1 - 0.0015 18.6 7.6 0.04 14.0 1.3 2.6 2 0 0 2 2 2 2 GRF zinc finger YrzO PF14142.6 EMR63763.1 - 0.16 11.8 0.3 0.37 10.7 0.3 1.5 1 0 0 1 1 1 0 YrzO-like protein HNF-1_N PF04814.13 EMR63763.1 - 0.32 11.6 1.1 0.46 11.1 1.1 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Tti2 PF10521.9 EMR63764.1 - 5.7e-87 291.8 0.1 7.4e-87 291.4 0.1 1.2 1 0 0 1 1 1 1 Tti2 family Peptidase_S8 PF00082.22 EMR63765.1 - 6.2e-41 140.6 2.8 2.3e-38 132.2 2.8 2.3 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EMR63765.1 - 8.5e-15 55.5 0.0 2e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 EMR63765.1 - 0.04 13.8 0.1 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain BclA_C PF18573.1 EMR63765.1 - 7.7 6.5 6.8 19 5.2 0.2 4.2 3 1 1 4 4 4 0 BclA C-terminal domain MFS_1 PF07690.16 EMR63766.1 - 1.1e-32 113.4 39.5 1.1e-32 113.4 39.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR63766.1 - 4.6e-05 22.5 23.3 8.4e-05 21.6 23.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Suf PF05843.14 EMR63767.1 - 9.4e-11 42.2 9.3 0.027 14.5 1.7 6.3 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EMR63767.1 - 4.3e-10 39.5 20.9 1.4 10.0 0.0 11.4 10 2 2 12 12 11 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EMR63767.1 - 2.6e-07 30.7 8.0 0.46 10.5 0.1 6.6 7 1 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 EMR63767.1 - 1e-05 24.9 9.4 0.00014 21.2 1.0 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMR63767.1 - 4.3e-05 23.7 1.3 3.4 8.0 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 EMR63767.1 - 0.00027 20.7 1.7 0.032 13.9 0.3 3.8 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_8 PF13181.6 EMR63767.1 - 0.00044 20.2 4.2 0.99 9.8 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR63767.1 - 0.0042 17.6 0.5 44 4.7 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EMR63767.1 - 0.0064 15.7 13.4 0.066 12.3 0.7 5.5 2 2 1 5 5 5 1 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 EMR63767.1 - 0.063 13.4 15.2 16 5.9 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 EMR63767.1 - 0.1 12.7 0.2 0.9 9.7 0.1 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 EMR63767.1 - 0.11 11.9 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_10 PF13374.6 EMR63767.1 - 0.4 10.6 10.5 71 3.5 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Sugar_tr PF00083.24 EMR63768.1 - 3.2e-46 158.1 16.1 9.3e-46 156.6 15.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR63768.1 - 2.3e-11 43.2 18.6 1.1e-10 41.0 18.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily PolyA_pol PF01743.20 EMR63769.1 - 1.2e-26 93.6 0.1 2.2e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EMR63769.1 - 3e-07 30.1 0.0 6.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EMR63769.1 - 9.1e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative His_Me_b4a2 PF18275.1 EMR63769.1 - 0.037 14.1 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain ATP-synt_D PF01813.17 EMR63770.1 - 2.9e-36 125.2 6.1 2.1e-30 106.1 1.0 3.1 1 1 1 2 2 2 2 ATP synthase subunit D ZapD PF07072.11 EMR63770.1 - 0.082 12.7 0.8 0.13 12.0 0.8 1.3 1 0 0 1 1 1 0 Cell division protein HisKA_3 PF07730.13 EMR63770.1 - 0.37 11.3 0.1 0.37 11.3 0.1 2.4 4 0 0 4 4 4 0 Histidine kinase Ribonuc_L-PSP PF01042.21 EMR63771.1 - 1.9e-20 73.1 0.0 2.4e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_9 PF08021.11 EMR63771.1 - 0.036 14.3 0.2 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Pec_lyase_C PF00544.19 EMR63773.1 - 1.4e-13 51.0 8.6 2.7e-12 46.7 8.6 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EMR63773.1 - 1.1e-05 25.4 11.4 0.0018 18.2 8.8 2.3 1 1 1 2 2 2 2 Right handed beta helix region Syja_N PF02383.18 EMR63774.1 - 2.5e-76 257.0 0.0 5.2e-76 256.0 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain RAM PF15320.6 EMR63774.1 - 0.049 14.2 0.4 0.049 14.2 0.4 4.7 3 1 1 4 4 4 0 mRNA cap methylation, RNMT-activating mini protein Mito_fiss_reg PF05308.11 EMR63774.1 - 1.6 8.7 9.2 5 7.1 9.2 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 EMR63774.1 - 4.5 7.3 5.3 9.4 6.3 5.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Citrate_synt PF00285.21 EMR63776.1 - 4.2e-99 332.0 0.0 5e-99 331.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF4360 PF14273.6 EMR63777.1 - 1.9e-65 220.0 5.0 2.2e-65 219.9 5.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MIP PF00230.20 EMR63778.1 - 1.3e-26 93.7 1.1 1.8e-26 93.3 1.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein RhlB PF12300.8 EMR63778.1 - 0.013 15.6 0.5 0.027 14.6 0.5 1.4 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB AAA_16 PF13191.6 EMR63779.1 - 5.8e-09 36.6 0.3 2.2e-08 34.7 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EMR63779.1 - 9.7e-06 25.7 0.1 1.6e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EMR63779.1 - 0.026 14.3 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2141 PF09912.9 EMR63779.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF815 PF05673.13 EMR63779.1 - 0.075 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PRORP PF16953.5 EMR63779.1 - 0.086 12.3 0.2 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein-only RNase P AAA_7 PF12775.7 EMR63779.1 - 0.098 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EMR63779.1 - 0.2 11.9 0.5 0.8 10.0 0.5 1.9 1 1 0 1 1 1 0 AAA domain IF-2B PF01008.17 EMR63782.1 - 9.7e-45 152.9 0.0 1.3e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family RepL PF05732.11 EMR63782.1 - 0.031 13.7 0.0 0.06 12.8 0.0 1.5 1 1 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Transp_cyt_pur PF02133.15 EMR63783.1 - 5.1e-95 318.8 35.0 6.4e-95 318.5 35.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin E1-E2_ATPase PF00122.20 EMR63783.1 - 0.44 10.1 7.0 1.7 8.2 0.1 3.0 3 0 0 3 3 3 0 E1-E2 ATPase adh_short PF00106.25 EMR63784.1 - 3.9e-19 68.9 0.4 2.5e-18 66.3 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63784.1 - 2.1e-11 43.8 0.0 4.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GMC_oxred_C PF05199.13 EMR63784.1 - 3.4e-11 43.9 0.1 4.5e-09 37.0 0.0 3.6 4 0 0 4 4 4 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR63784.1 - 1.2e-06 28.1 0.0 4.4e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR63784.1 - 0.0003 20.0 0.3 0.00054 19.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_1 PF00561.20 EMR63784.1 - 0.0011 18.7 0.0 0.023 14.4 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold KR PF08659.10 EMR63784.1 - 0.0015 18.5 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 KR domain Hydrolase_4 PF12146.8 EMR63784.1 - 0.0091 15.3 0.4 2.1 7.6 0.0 3.3 4 0 0 4 4 4 1 Serine aminopeptidase, S33 FAD_oxidored PF12831.7 EMR63784.1 - 0.023 14.1 0.3 0.034 13.5 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR63784.1 - 0.028 14.7 0.7 0.085 13.1 0.7 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Epimerase PF01370.21 EMR63784.1 - 0.043 13.3 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 EMR63784.1 - 0.052 12.8 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF900 PF05990.12 EMR63784.1 - 0.21 11.1 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Malic_M PF03949.15 EMR63785.1 - 7.9e-94 313.7 0.0 1e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EMR63785.1 - 8.4e-69 231.0 0.0 1.4e-68 230.3 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PadR PF03551.14 EMR63785.1 - 0.047 13.6 0.1 0.41 10.6 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF3632 PF12311.8 EMR63786.1 - 9.1e-17 62.0 0.3 1.3e-16 61.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ELFV_dehydrog PF00208.21 EMR63787.1 - 2.9e-30 105.8 0.1 3.3e-30 105.6 0.1 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Qn_am_d_aIV PF09100.10 EMR63787.1 - 0.00072 19.4 0.1 0.00079 19.3 0.1 1.2 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV Ras PF00071.22 EMR63788.1 - 2.8e-65 218.9 0.5 3.3e-65 218.6 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR63788.1 - 1.1e-35 122.4 0.1 1.9e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR63788.1 - 4.2e-16 58.9 0.1 5.2e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EMR63788.1 - 4.1e-05 23.6 0.3 0.15 11.9 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMR63788.1 - 4.3e-05 23.6 0.0 0.00015 21.8 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMR63788.1 - 0.00014 21.5 0.3 0.00035 20.2 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMR63788.1 - 0.00038 19.9 0.1 0.00049 19.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMR63788.1 - 0.00067 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EMR63788.1 - 0.0024 18.3 0.1 0.24 11.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EMR63788.1 - 0.0071 15.9 0.0 0.04 13.4 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EMR63788.1 - 0.01 16.2 0.0 0.014 15.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EMR63788.1 - 0.05 13.9 0.0 0.095 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EMR63788.1 - 0.055 12.9 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 EMR63788.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EMR63788.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EMR63788.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EMR63788.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Septin MCM PF00493.23 EMR63788.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 EMR63788.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PBP1_TM PF14812.6 EMR63789.1 - 0.15 12.5 6.0 1.9 8.9 2.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 EMR63789.1 - 0.26 11.0 11.4 0.39 10.4 11.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AJAP1_PANP_C PF15298.6 EMR63789.1 - 1.1 9.5 7.1 3 8.0 1.7 2.3 2 0 0 2 2 2 0 AJAP1/PANP C-terminus RTA1 PF04479.13 EMR63790.1 - 1.6e-39 135.7 13.0 1.6e-39 135.7 13.0 2.3 2 1 0 2 2 2 1 RTA1 like protein F-box-like PF12937.7 EMR63790.1 - 0.00077 19.3 0.2 0.0021 17.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like Fels1 PF05666.11 EMR63790.1 - 0.18 11.4 0.1 0.42 10.3 0.1 1.5 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like p450 PF00067.22 EMR63792.1 - 3.8e-57 194.1 0.0 4.8e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb6 PF01192.22 EMR63793.1 - 6.6e-17 61.2 0.1 1.2e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 p450 PF00067.22 EMR63794.1 - 1.1e-34 120.0 0.0 1.5e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 EMR63795.1 - 7.6e-28 95.4 43.8 3.6e-05 24.0 0.2 10.5 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR63795.1 - 5.3e-17 61.1 50.3 0.034 15.0 0.5 10.8 11 0 0 11 11 11 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMR63795.1 - 1.5e-07 31.5 51.5 0.00082 19.7 0.6 10.1 10 1 0 10 10 10 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMR63795.1 - 1.6e-06 28.3 23.2 0.19 12.1 1.3 8.9 10 0 0 10 10 10 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EMR63795.1 - 1.8e-05 25.3 27.9 0.012 16.2 0.1 7.6 6 2 2 9 9 9 4 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 EMR63795.1 - 0.00011 22.8 15.2 0.012 16.2 0.7 5.6 3 1 2 5 5 5 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 EMR63795.1 - 0.00012 22.3 13.9 0.31 11.5 0.0 6.0 6 0 0 6 6 5 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EMR63795.1 - 0.00028 21.1 23.3 0.064 13.4 0.6 5.4 3 1 4 7 7 6 2 Aberrant zinc-finger Ogr_Delta PF04606.12 EMR63795.1 - 0.0033 17.4 0.6 0.073 13.1 0.2 2.8 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger MerB PF03243.15 EMR63795.1 - 0.0051 17.0 0.2 0.015 15.4 0.2 1.9 1 0 0 1 1 1 1 Alkylmercury lyase zf-C2H2_8 PF15909.5 EMR63795.1 - 0.017 15.4 19.1 0.16 12.2 5.2 4.6 4 1 1 5 5 5 0 C2H2-type zinc ribbon zf_Hakai PF18408.1 EMR63795.1 - 0.067 12.9 0.1 0.067 12.9 0.1 7.3 8 0 0 8 8 8 0 C2H2 Hakai zinc finger domain zf-H2C2_5 PF13909.6 EMR63795.1 - 0.85 9.4 0.0 0.85 9.4 0.0 9.7 11 1 0 11 11 10 0 C2H2-type zinc-finger domain BBP1_N PF15271.6 EMR63795.1 - 2.2 9.1 4.4 19 6.0 0.0 2.9 2 1 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein CHORD PF04968.12 EMR63795.1 - 6.8 7.5 21.3 27 5.6 0.4 5.8 4 1 2 6 6 6 0 CHORD Esterase PF00756.20 EMR63796.1 - 1e-52 179.3 0.0 1.2e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EMR63796.1 - 0.00044 19.6 0.0 0.0012 18.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR63796.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EMR63796.1 - 0.006 15.5 0.0 0.014 14.3 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EMR63796.1 - 0.013 16.1 0.0 0.017 15.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EMR63796.1 - 0.026 14.0 0.1 0.059 12.8 0.1 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 EMR63796.1 - 0.097 12.2 0.1 0.12 11.8 0.1 1.3 1 1 0 1 1 1 0 Esterase PHB depolymerase Adhesin_P1_N PF18652.1 EMR63796.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain Abhydrolase_3 PF07859.13 EMR63797.1 - 6.5e-21 75.2 0.1 6.6e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EMR63797.1 - 5.3e-06 26.2 0.0 5.9e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 EMR63797.1 - 9.8e-05 22.6 0.0 0.0001 22.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 EMR63797.1 - 0.00019 21.3 0.0 0.0002 21.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EMR63797.1 - 0.00031 20.1 0.0 0.00033 20.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMR63797.1 - 0.00057 19.4 0.0 0.0017 17.9 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.14 EMR63797.1 - 0.0009 18.6 0.0 0.001 18.5 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.7 EMR63797.1 - 0.001 19.7 0.6 0.0011 19.6 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EMR63797.1 - 0.0035 17.0 0.0 0.0037 16.9 0.0 1.1 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.8 EMR63797.1 - 0.0043 16.6 0.0 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.12 EMR63797.1 - 0.022 13.4 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 EMR63797.1 - 0.026 14.0 0.2 0.047 13.2 0.1 1.5 1 1 1 2 2 2 0 Esterase PHB depolymerase DLH PF01738.18 EMR63797.1 - 0.03 13.9 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 EMR63797.1 - 0.038 13.9 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Lipase (class 3) ABATE PF07336.11 EMR63797.1 - 0.05 14.3 1.2 0.05 14.3 1.2 1.4 1 1 0 1 1 1 0 Putative stress-induced transcription regulator VirJ PF06057.11 EMR63797.1 - 0.075 12.9 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) BAAT_C PF08840.11 EMR63797.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MFS_1 PF07690.16 EMR63798.1 - 1.3e-23 83.5 20.8 1.5e-16 60.3 7.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CPSF_A PF03178.15 EMR63798.1 - 0.22 10.8 0.0 0.49 9.6 0.0 1.6 1 1 0 1 1 1 0 CPSF A subunit region DUF2070 PF09843.9 EMR63798.1 - 1.4 7.1 15.8 0.044 12.1 4.8 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) 2-Hacid_dh_C PF02826.19 EMR63799.1 - 3e-41 140.7 0.0 4e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR63799.1 - 1.7e-10 40.7 0.0 2.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMR63799.1 - 0.011 16.0 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMR63799.1 - 0.11 13.1 0.2 0.26 11.9 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent WaaY PF06176.11 EMR63800.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Baculo_PEP_C PF04513.12 EMR63801.1 - 0.005 16.9 0.7 2.7 8.1 0.0 3.3 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus ETRAMP PF09716.10 EMR63801.1 - 0.38 10.9 1.7 35 4.5 0.0 3.5 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) EI24 PF07264.11 EMR63801.1 - 1.3 9.2 9.4 2.9 8.1 0.1 3.4 3 1 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) PAPA-1 PF04795.12 EMR63802.1 - 1.6e-29 102.5 5.0 1.6e-29 102.5 5.0 3.8 4 1 0 4 4 4 1 PAPA-1-like conserved region COMM_domain PF07258.14 EMR63803.1 - 0.16 12.1 1.2 30 4.8 0.0 3.0 3 0 0 3 3 3 0 COMM domain Pex14_N PF04695.13 EMR63804.1 - 2.4e-33 116.0 6.1 2.4e-33 116.0 6.1 2.6 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_23 PF13489.6 EMR63806.1 - 1.9e-14 53.8 0.0 2.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR63806.1 - 6.6e-12 46.0 0.0 1.1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR63806.1 - 2.3e-10 41.1 0.0 2e-09 38.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR63806.1 - 5.9e-09 35.9 0.0 6.9e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR63806.1 - 1.5e-07 31.9 0.0 2.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMR63806.1 - 0.0031 17.0 0.1 0.041 13.3 0.0 2.4 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.14 EMR63806.1 - 0.0046 16.5 0.0 0.077 12.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EMR63806.1 - 0.0054 16.1 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EMR63806.1 - 0.028 13.7 0.0 0.19 11.0 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EMR63806.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 EMR63806.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 EMR63806.1 - 0.23 11.2 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PikAIV_N PF18605.1 EMR63806.1 - 0.41 10.3 2.4 0.73 9.5 2.4 1.4 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain p450 PF00067.22 EMR63807.1 - 6.7e-70 236.1 0.0 8.6e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EMR63807.1 - 1.5e-24 86.9 0.1 2.6e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EMR63807.1 - 9.9e-20 71.2 0.0 2.2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EMR63807.1 - 1.4e-14 54.6 0.0 9.3e-14 52.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain p450 PF00067.22 EMR63808.1 - 8e-63 212.8 0.0 1.7e-62 211.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Dicty_REP PF05086.12 EMR63808.1 - 0.17 9.8 2.7 0.24 9.4 2.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4481 PF14800.6 EMR63808.1 - 0.18 11.2 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Phage_Gp23 PF10669.9 EMR63808.1 - 0.22 11.9 2.9 0.44 10.9 2.9 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) FAD_binding_4 PF01565.23 EMR63809.1 - 1.2e-11 44.5 0.3 1.6e-10 40.9 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain adh_short PF00106.25 EMR63810.1 - 1.8e-31 109.2 0.2 2.1e-18 66.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63810.1 - 1.7e-20 73.6 0.3 1.9e-14 53.8 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EMR63810.1 - 1.4e-06 28.4 0.1 2.2e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR63810.1 - 0.00033 20.3 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 EMR63810.1 - 0.00067 19.6 0.1 0.0011 19.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.10 EMR63810.1 - 0.0022 17.9 0.7 0.0067 16.4 0.2 2.0 3 0 0 3 3 3 1 KR domain DFP PF04127.15 EMR63810.1 - 0.0023 17.8 0.2 0.0035 17.2 0.2 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_2 PF03446.15 EMR63810.1 - 0.0024 18.0 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMR63810.1 - 0.0043 17.6 0.0 0.0084 16.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 EMR63810.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMR63810.1 - 0.015 14.8 0.0 0.077 12.4 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EMR63810.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EMR63810.1 - 0.081 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 EMR63810.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SET PF00856.28 EMR63811.1 - 6e-06 26.7 0.0 9.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 SET domain CtaG_Cox11 PF04442.14 EMR63812.1 - 9.7e-59 197.7 0.0 1.7e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Amino_oxidase PF01593.24 EMR63812.1 - 1.4e-14 54.2 0.2 1.3e-06 28.0 0.0 3.1 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR63812.1 - 4.1e-11 42.9 0.0 9.2e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR63812.1 - 0.00068 19.0 0.0 0.039 13.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR63812.1 - 0.003 17.2 0.4 0.031 13.8 0.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR63812.1 - 0.0049 16.9 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EMR63812.1 - 0.13 11.0 0.0 2.9 6.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Peptidase_S32 PF05579.13 EMR63814.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.6 EMR63814.1 - 0.026 15.4 0.0 7.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Trypsin-like peptidase domain RNase_H PF00075.24 EMR63815.1 - 1.5e-06 28.4 0.0 2.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNase H WD40 PF00400.32 EMR63816.1 - 8.6e-30 102.4 10.7 7.7e-06 26.6 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 EMR63816.1 - 1.4e-29 102.2 17.2 2.3e-29 101.5 17.2 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 EMR63816.1 - 2e-10 40.8 0.3 0.029 14.6 0.0 5.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMR63816.1 - 4e-05 23.6 1.3 0.00029 20.8 0.2 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EMR63816.1 - 0.00021 20.4 0.1 0.011 14.8 0.0 3.0 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EMR63816.1 - 0.00023 21.2 0.0 3.3 7.8 0.0 4.5 2 2 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 EMR63816.1 - 0.0012 17.7 3.0 0.062 12.0 0.5 3.1 2 2 0 2 2 2 1 Nup133 N terminal like RICH PF05062.12 EMR63816.1 - 0.074 13.4 4.6 0.14 12.5 4.6 1.5 1 0 0 1 1 1 0 RICH domain RPN6_N PF18055.1 EMR63817.1 - 7.2e-47 158.6 2.0 2.8e-46 156.6 0.5 2.6 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EMR63817.1 - 8.6e-20 71.2 0.5 3.4e-19 69.3 0.1 2.2 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EMR63817.1 - 2.3e-11 43.2 0.9 5.8e-11 41.9 0.9 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 EMR63817.1 - 5.5e-05 22.9 0.2 9.7e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 DDRGK domain TPR_MalT PF17874.1 EMR63817.1 - 0.00061 19.3 1.2 0.00061 19.3 1.2 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 EMR63817.1 - 0.0073 16.3 2.1 5.5 7.3 0.6 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Med2 PF11214.8 EMR63817.1 - 0.025 14.7 0.0 0.19 11.9 0.1 2.4 2 0 0 2 2 2 0 Mediator complex subunit 2 TPR_12 PF13424.6 EMR63817.1 - 0.038 14.3 18.2 0.085 13.2 1.4 5.2 5 1 2 7 7 7 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 EMR63817.1 - 0.074 13.0 0.1 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TPR_1 PF00515.28 EMR63817.1 - 0.087 12.7 0.7 21 5.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMR63817.1 - 0.34 11.1 4.7 24 5.4 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF4398 PF14346.6 EMR63817.1 - 5.6 7.7 10.2 0.67 10.6 0.2 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4398) AMPKBI PF04739.15 EMR63818.1 - 2.8e-26 91.6 2.5 1.1e-25 89.6 2.5 2.1 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 EMR63818.1 - 9e-24 83.5 0.0 1.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase FAM104 PF15434.6 EMR63819.1 - 0.061 13.9 10.5 1.3 9.6 7.0 2.6 2 0 0 2 2 2 0 Family 104 Red1 PF07964.11 EMR63819.1 - 9.1 4.4 12.2 11 4.1 12.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 adh_short_C2 PF13561.6 EMR63820.1 - 4.3e-08 33.0 0.0 7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR63820.1 - 4.3e-05 23.1 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 EMR63820.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EMR63820.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Activator_LAG-3 PF11498.8 EMR63821.1 - 0.0016 17.5 3.9 0.0021 17.1 3.9 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Ndc1_Nup PF09531.10 EMR63821.1 - 0.044 12.5 1.2 0.049 12.3 1.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 EMR63821.1 - 0.77 8.5 8.3 0.91 8.3 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOBP PF15279.6 EMR63821.1 - 1.2 9.7 6.4 1.4 9.4 6.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.9 EMR63821.1 - 1.5 7.3 12.0 2 6.9 12.0 1.1 1 0 0 1 1 1 0 Macoilin family Rrn6 PF10214.9 EMR63821.1 - 3.6 6.0 8.0 4.3 5.7 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GREB1 PF15782.5 EMR63821.1 - 7.6 3.5 7.7 9.7 3.2 7.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer POT1 PF02765.17 EMR63822.1 - 1.4e-09 38.0 0.0 2.8e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 adh_short PF00106.25 EMR63823.1 - 2e-34 118.8 0.0 3.4e-34 118.0 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63823.1 - 3.6e-27 95.4 0.0 5.1e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR63823.1 - 0.0017 18.3 2.4 0.026 14.5 0.6 2.8 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 EMR63823.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR63823.1 - 0.058 13.3 0.2 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding DUF4281 PF14108.6 EMR63825.1 - 0.11 12.8 5.1 3.9 7.8 5.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4281) PTR2 PF00854.21 EMR63826.1 - 5.8e-43 147.2 6.0 1e-33 116.8 0.3 2.1 1 1 1 2 2 2 2 POT family Bacteriocin_IId PF09221.10 EMR63826.1 - 8.1 6.7 9.0 1.5 9.1 1.8 2.9 1 1 1 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like GFO_IDH_MocA PF01408.22 EMR63827.1 - 8.3e-11 42.8 1.7 4.1e-10 40.5 1.7 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 EMR63827.1 - 0.034 14.7 0.0 0.064 13.8 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain NAD_binding_3 PF03447.16 EMR63827.1 - 0.057 14.1 0.0 0.09 13.4 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Rox3 PF08633.10 EMR63828.1 - 5.2e-68 229.4 0.7 6.6e-68 229.0 0.7 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit UQ_con PF00179.26 EMR63829.1 - 4.8e-36 123.5 0.0 6.1e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Astro_capsid_p PF12226.8 EMR63829.1 - 9.6 5.2 7.5 11 5.0 7.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EBP PF05241.12 EMR63830.1 - 3e-71 238.5 3.7 3.5e-71 238.3 3.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein Cauli_VI PF01693.16 EMR63831.1 - 3.3e-32 110.5 5.1 3.9e-16 59.1 1.2 2.9 3 0 0 3 3 3 2 Caulimovirus viroplasmin MARVEL PF01284.23 EMR63832.1 - 5.2e-08 33.0 7.1 8.1e-08 32.4 7.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.6 EMR63832.1 - 0.058 13.8 1.8 0.096 13.1 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) DUF2615 PF11027.8 EMR63832.1 - 1.2 9.3 2.9 5 7.3 0.1 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF2615) zf-RING_2 PF13639.6 EMR63833.1 - 2.9e-10 40.3 6.1 6.1e-10 39.3 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EMR63833.1 - 1.1e-07 32.1 3.5 2.7e-07 30.8 3.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EMR63833.1 - 8.1e-07 28.8 5.4 8.1e-07 28.8 5.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMR63833.1 - 1.5e-06 27.8 4.1 1.5e-06 27.8 4.1 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EMR63833.1 - 3.5e-05 23.5 5.8 3.5e-05 23.5 5.8 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR63833.1 - 3.8e-05 23.6 2.3 3.8e-05 23.6 2.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMR63833.1 - 0.00023 21.1 2.4 0.00058 19.9 2.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EMR63833.1 - 0.00027 20.7 3.6 0.00027 20.7 3.6 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EMR63833.1 - 0.00038 20.5 3.9 0.0008 19.5 3.9 1.6 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 EMR63833.1 - 0.0018 17.8 3.4 0.0037 16.8 3.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EMR63833.1 - 0.0053 16.7 4.4 0.0053 16.7 4.4 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EMR63833.1 - 0.024 14.8 4.0 0.092 12.9 4.0 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EMR63833.1 - 0.031 14.5 6.6 0.058 13.6 5.2 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 EMR63833.1 - 0.088 13.1 3.8 0.17 12.2 3.8 1.5 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 EMR63833.1 - 0.13 12.1 6.7 0.26 11.2 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CNDH2_M PF16869.5 EMR63834.1 - 0.068 13.9 0.1 0.27 11.9 0.0 1.8 2 0 0 2 2 2 0 PF16858 DHDPS PF00701.22 EMR63835.1 - 4.3e-33 114.3 0.0 5.4e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family AP_endonuc_2 PF01261.24 EMR63835.1 - 0.044 13.2 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel SMC_N PF02463.19 EMR63836.1 - 7.2e-51 172.7 30.1 3e-50 170.7 30.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMR63836.1 - 1.1e-23 83.8 0.0 8.9e-23 80.8 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 EMR63836.1 - 5.1e-08 32.5 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EMR63836.1 - 8e-07 29.1 19.9 4.6e-05 23.4 0.2 4.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 EMR63836.1 - 2e-06 26.9 127.7 0.0051 15.7 11.2 7.2 3 2 4 7 7 7 5 Spc7 kinetochore protein DUF3584 PF12128.8 EMR63836.1 - 2e-05 22.4 109.6 0.0013 16.4 20.0 4.3 4 0 0 4 4 4 4 Protein of unknown function (DUF3584) EzrA PF06160.12 EMR63836.1 - 0.00055 18.2 18.0 0.00055 18.2 18.0 5.5 3 2 0 4 4 3 2 Septation ring formation regulator, EzrA AAA_15 PF13175.6 EMR63836.1 - 0.001 18.8 21.8 0.001 18.8 21.8 5.7 2 2 3 5 5 4 1 AAA ATPase domain MscS_porin PF12795.7 EMR63836.1 - 0.0051 16.4 15.1 0.0051 16.4 15.1 5.8 3 2 2 5 5 5 2 Mechanosensitive ion channel porin domain SbcCD_C PF13558.6 EMR63836.1 - 0.006 16.8 0.0 0.033 14.4 0.0 2.4 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit CENP-F_leu_zip PF10473.9 EMR63836.1 - 0.063 13.3 116.0 0.013 15.6 18.9 6.5 5 1 1 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FPP PF05911.11 EMR63836.1 - 0.23 9.6 103.3 0.0053 15.0 24.2 4.3 2 1 1 4 4 4 0 Filament-like plant protein, long coiled-coil DASH_Dam1 PF08653.10 EMR63836.1 - 3.6 7.4 8.0 20 5.1 0.4 4.6 3 1 0 3 3 3 0 DASH complex subunit Dam1 UBA_4 PF14555.6 EMR63837.1 - 4e-08 32.9 0.1 7.9e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain DnaJ_C PF01556.18 EMR63838.1 - 1.3e-36 125.9 0.9 1.8e-36 125.5 0.9 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMR63838.1 - 4.4e-27 94.0 3.8 6.9e-27 93.4 3.8 1.3 1 0 0 1 1 1 1 DnaJ domain Grg1 PF11034.8 EMR63839.1 - 2e-28 98.4 18.0 2.2e-28 98.3 18.0 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 BTB PF00651.31 EMR63842.1 - 1.6e-16 60.5 0.0 1.9e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans_2 PF11951.8 EMR63843.1 - 7.8e-52 176.4 0.8 1.2e-51 175.8 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nop16 PF09420.10 EMR63844.1 - 5.3e-67 225.9 11.2 6.7e-67 225.6 11.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 PCM1_C PF15717.5 EMR63844.1 - 0.032 12.9 4.0 0.037 12.7 4.0 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus NOA36 PF06524.12 EMR63844.1 - 0.088 12.1 4.1 0.11 11.8 4.1 1.3 1 0 0 1 1 1 0 NOA36 protein CAF1A PF12253.8 EMR63844.1 - 0.24 11.6 13.1 1.1 9.5 10.3 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A DUF2722 PF10846.8 EMR63844.1 - 0.59 9.0 5.2 0.75 8.7 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DNA_pol_phi PF04931.13 EMR63844.1 - 0.73 7.9 11.9 0.94 7.5 11.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EMR63844.1 - 0.95 7.7 10.0 1.1 7.4 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF5476 PF17570.2 EMR63844.1 - 1 9.8 7.0 0.25 11.8 0.7 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5476) Cwf_Cwc_15 PF04889.12 EMR63844.1 - 1.5 8.5 20.9 3.1 7.4 20.9 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 EMR63844.1 - 5.8 5.3 8.9 8.7 4.7 8.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 INCENP_ARK-bind PF03941.15 EMR63844.1 - 9.9 6.2 14.3 7.5 6.6 1.0 2.6 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region DUF2838 PF10998.8 EMR63845.1 - 1.3e-43 147.7 11.2 1.3e-43 147.7 11.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Spc7 PF08317.11 EMR63845.1 - 0.00091 18.2 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Apolipoprotein PF01442.18 EMR63845.1 - 0.0016 18.3 4.2 0.0024 17.8 3.7 1.5 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 EMR63845.1 - 0.011 15.3 0.2 0.027 14.0 0.2 1.7 1 1 0 1 1 1 0 fzo-like conserved region DHR10 PF18595.1 EMR63845.1 - 0.37 10.9 8.1 0.78 9.8 8.1 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF3584 PF12128.8 EMR63845.1 - 1.2 6.6 5.5 1.6 6.1 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MFS_1 PF07690.16 EMR63846.1 - 2.2e-38 132.1 43.3 2.2e-38 132.1 43.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR63846.1 - 1.1e-14 54.1 10.9 1.1e-14 54.1 10.9 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EMR63846.1 - 2.3e-05 23.4 11.8 0.0043 16.0 0.1 2.4 2 1 0 2 2 2 2 MFS_1 like family TRI12 PF06609.13 EMR63846.1 - 0.0068 14.9 12.4 0.0098 14.3 11.0 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) APH PF01636.23 EMR63849.1 - 1.1e-07 32.0 4.8 1.8e-07 31.4 4.8 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMR63849.1 - 0.0038 16.8 0.2 0.038 13.6 0.1 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Glyco_hydro_71 PF03659.14 EMR63850.1 - 7.5e-148 492.3 3.5 9.5e-148 492.0 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF2406 PF10295.9 EMR63851.1 - 1.1e-25 90.1 0.3 1.1e-25 90.1 0.3 2.5 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Spt20 PF12090.8 EMR63851.1 - 4.3 6.9 16.7 8.4 5.9 16.7 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 EMR63851.1 - 5.1 7.0 23.7 9.4 6.1 23.6 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L35Ae PF01247.18 EMR63852.1 - 7.6e-42 141.4 0.4 8.5e-42 141.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EMR63852.1 - 2.8e-05 24.2 0.0 0.025 14.8 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Sugar_tr PF00083.24 EMR63853.1 - 4.2e-80 269.8 22.6 5.2e-80 269.5 22.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR63853.1 - 1.2e-24 86.9 32.0 5.8e-24 84.7 31.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR63853.1 - 1.3e-06 27.2 3.4 2.1e-06 26.5 3.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2929 PF11151.8 EMR63853.1 - 5.8 7.3 14.4 5.9 7.3 5.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) ABC_membrane PF00664.23 EMR63854.1 - 1.4e-85 287.3 41.9 2.9e-53 181.3 20.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMR63854.1 - 3.7e-63 212.1 0.0 1.6e-29 103.2 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMR63854.1 - 1.9e-15 56.9 2.5 3.5e-07 29.9 2.4 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMR63854.1 - 3.7e-08 33.9 0.1 0.0034 17.8 0.1 3.2 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMR63854.1 - 4.5e-08 33.2 0.1 0.00045 20.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EMR63854.1 - 6.1e-08 33.0 0.2 0.037 14.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 EMR63854.1 - 1.2e-07 30.9 0.0 0.045 12.5 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EMR63854.1 - 4.7e-07 29.5 0.7 0.00065 19.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EMR63854.1 - 6.8e-07 29.4 0.1 0.29 10.9 0.0 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMR63854.1 - 2.2e-06 27.7 4.3 0.049 13.3 2.4 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EMR63854.1 - 3.8e-05 23.5 0.5 0.14 11.9 0.0 3.6 4 0 0 4 4 4 2 AAA domain DUF3987 PF13148.6 EMR63854.1 - 6.8e-05 22.0 0.2 0.00012 21.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) AAA PF00004.29 EMR63854.1 - 0.00012 22.5 0.7 12 6.4 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EMR63854.1 - 0.00015 21.8 0.0 0.078 12.9 0.1 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 EMR63854.1 - 0.00068 19.3 0.0 0.6 9.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.25 EMR63854.1 - 0.00078 19.2 0.0 0.77 9.4 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 EMR63854.1 - 0.001 18.6 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 EMR63854.1 - 0.0013 18.8 0.0 2.2 8.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EMR63854.1 - 0.0015 18.7 2.1 2.3 8.5 0.3 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EMR63854.1 - 0.0025 18.4 0.1 2 9.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EMR63854.1 - 0.0035 17.4 0.4 0.34 10.9 0.2 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EMR63854.1 - 0.0045 17.5 0.1 0.0045 17.5 0.1 3.2 2 1 0 3 3 2 1 AAA domain PRK PF00485.18 EMR63854.1 - 0.0065 16.2 0.1 3 7.6 0.1 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 EMR63854.1 - 0.021 15.0 0.1 3.2 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMR63854.1 - 0.022 14.9 0.3 1.2 9.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 EMR63854.1 - 0.03 14.0 0.4 12 5.5 0.2 3.4 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EMR63854.1 - 0.034 13.9 0.2 4.7 6.9 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EMR63854.1 - 0.044 13.1 0.2 13 5.0 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin DUF87 PF01935.17 EMR63854.1 - 0.062 13.4 0.0 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 EMR63854.1 - 0.07 12.3 0.1 4.4 6.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.7 EMR63854.1 - 0.12 11.3 0.1 0.24 10.3 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain ATPase_2 PF01637.18 EMR63854.1 - 0.12 12.2 2.3 0.84 9.5 0.3 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Roc PF08477.13 EMR63854.1 - 0.3 11.3 2.2 34 4.7 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase VMA21 PF09446.10 EMR63855.1 - 3e-16 59.3 8.7 4.3e-16 58.8 8.7 1.2 1 0 0 1 1 1 1 VMA21-like domain TraQ PF09679.10 EMR63855.1 - 0.033 14.1 0.1 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF1772 PF08592.11 EMR63855.1 - 0.036 14.4 0.1 0.04 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Peptidase_C48 PF02902.19 EMR63856.1 - 2e-15 57.2 0.1 4.9e-15 55.9 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SAICAR_synt PF01259.18 EMR63857.1 - 3.4e-48 164.5 0.0 4.4e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase G6PD_C PF02781.16 EMR63858.1 - 6.3e-115 383.3 0.0 1e-114 382.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EMR63858.1 - 2.6e-60 204.1 0.0 4.8e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain AMP-binding PF00501.28 EMR63860.1 - 2.6e-21 75.7 0.0 4.3e-21 75.0 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Sugar_tr PF00083.24 EMR63862.1 - 1.7e-72 244.7 19.6 2e-72 244.5 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR63862.1 - 8e-26 90.8 27.5 1.5e-25 89.9 26.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR63862.1 - 6e-05 21.7 1.9 6e-05 21.7 1.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EMR63862.1 - 7.2e-05 22.2 3.5 7.2e-05 22.2 3.5 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EMR63862.1 - 0.012 14.0 7.5 0.2 9.9 0.1 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Nuc_deoxyri_tr2 PF15891.5 EMR63863.1 - 5.9e-33 113.4 0.0 8.4e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like BLM10_mid PF16507.5 EMR63864.1 - 2.6e-203 676.4 0.0 4.1e-203 675.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EMR63864.1 - 1.4e-28 98.6 0.0 4.9e-28 96.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EMR63864.1 - 6.7e-21 74.4 0.0 2e-20 72.9 0.0 1.9 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 EMR63864.1 - 0.015 15.5 1.6 11 6.6 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat CENP-B_dimeris PF09026.10 EMR63864.1 - 4.9 7.6 7.7 16 5.9 7.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HOIP-UBA PF16678.5 EMR63865.1 - 0.088 12.8 0.2 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 HOIP UBA domain pair Mon2_C PF16206.5 EMR63866.1 - 0.022 12.9 0.0 0.87 7.6 0.0 2.0 2 0 0 2 2 2 0 C-terminal region of Mon2 protein GST_N_4 PF17172.4 EMR63867.1 - 1e-17 64.7 0.0 2.5e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EMR63867.1 - 1.8e-06 27.7 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR63867.1 - 0.0002 21.3 0.0 0.00042 20.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EMR63867.1 - 0.0036 17.6 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein adh_short PF00106.25 EMR63868.1 - 3.9e-12 46.0 0.0 2.1e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63868.1 - 1.7e-09 37.6 0.0 2.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR63869.1 - 1.3e-18 67.2 0.0 1.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63869.1 - 3e-11 43.4 0.0 3.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR63869.1 - 0.0035 16.8 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR63869.1 - 0.0036 16.7 0.0 0.038 13.4 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMR63869.1 - 0.0095 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 EMR63871.1 - 6.3e-16 58.2 0.7 9.4e-16 57.6 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TT_ORF2a PF08197.11 EMR63872.1 - 0.037 14.0 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 pORF2a truncated protein HERV-K_REC PF15695.5 EMR63872.1 - 0.13 12.3 0.1 0.33 11.1 0.1 1.7 1 1 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 MFS_1 PF07690.16 EMR63873.1 - 3e-24 85.6 49.9 1.1e-16 60.7 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMR63873.1 - 0.0008 18.8 33.8 0.0035 16.7 33.8 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Urotensin_II PF02083.15 EMR63873.1 - 6.4 6.7 5.9 29 4.6 0.9 2.6 2 0 0 2 2 2 0 Urotensin II LUC7 PF03194.15 EMR63874.1 - 1.4e-64 218.2 0.0 1.7e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DASH_Duo1 PF08651.10 EMR63874.1 - 0.044 13.6 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF4919 PF16266.5 EMR63874.1 - 0.2 11.6 0.1 0.63 10.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) DHHC PF01529.20 EMR63876.1 - 4.8e-10 39.7 9.4 6.3e-10 39.3 3.5 2.2 1 1 1 2 2 2 2 DHHC palmitoyltransferase H_PPase PF03030.16 EMR63876.1 - 0.03 12.9 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Pkinase PF00069.25 EMR63877.1 - 0.0079 15.6 0.0 0.83 9.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_L-PSP PF01042.21 EMR63878.1 - 8.9e-19 67.7 0.0 1.3e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.11 EMR63878.1 - 0.022 14.7 0.0 0.097 12.7 0.0 1.9 2 0 0 2 2 2 0 NOGCT (NUC087) domain DCB PF16213.5 EMR63879.1 - 2e-46 157.9 5.7 4.8e-46 156.7 5.7 1.6 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EMR63879.1 - 2.3e-42 144.6 0.5 2.1e-41 141.5 0.0 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Utp12 PF04003.12 EMR63879.1 - 3.2 8.1 10.2 21 5.5 0.1 4.2 3 2 1 4 4 4 0 Dip2/Utp12 Family Gpi16 PF04113.14 EMR63880.1 - 2.1e-239 795.7 0.0 2.7e-239 795.3 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component K_channel_TID PF07941.11 EMR63880.1 - 0.63 10.5 9.8 1.9 9.0 9.8 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RRM_1 PF00076.22 EMR63881.1 - 0.0055 16.5 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1682 PF07946.14 EMR63883.1 - 4.6 6.4 9.2 6 6.0 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1479 PF07350.12 EMR63884.1 - 1.8e-115 386.0 0.0 2.3e-115 385.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EMR63884.1 - 0.049 13.9 0.1 4.1 7.6 0.2 2.9 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Antifungal_pept PF11410.8 EMR63885.1 - 6.5 6.8 11.4 2.7 8.0 5.9 2.3 1 1 1 2 2 2 0 Antifungal peptide p450 PF00067.22 EMR63886.1 - 1.4e-54 185.6 0.0 2.3e-54 184.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 EMR63886.1 - 3.1e-35 121.8 0.4 8.7e-35 120.4 0.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR63886.1 - 5.5e-29 101.0 0.2 1.4e-28 99.7 0.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR63886.1 - 0.0017 18.3 1.6 0.0051 16.7 0.1 2.2 2 0 0 2 2 2 1 KR domain AAA PF00004.29 EMR63887.1 - 2.3e-25 89.5 0.0 4.2e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMR63887.1 - 6.1e-07 29.3 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain BCS1_N PF08740.11 EMR63887.1 - 3.9e-06 27.0 0.0 7.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal RNA_helicase PF00910.22 EMR63887.1 - 7.4e-05 23.1 0.0 0.00025 21.4 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EMR63887.1 - 0.00092 19.8 0.0 0.0019 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR63887.1 - 0.0011 19.3 0.2 0.0086 16.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EMR63887.1 - 0.0018 18.3 0.0 0.008 16.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EMR63887.1 - 0.0071 16.5 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMR63887.1 - 0.024 14.9 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMR63887.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 EMR63887.1 - 0.033 14.6 0.3 0.73 10.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 EMR63887.1 - 0.033 13.8 0.1 0.22 11.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMR63887.1 - 0.033 13.9 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EMR63887.1 - 0.049 12.8 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 EMR63887.1 - 0.087 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EMR63887.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 EMR63887.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EMR63887.1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MtrG PF04210.13 EMR63888.1 - 0.19 11.6 0.1 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Tyrosinase PF00264.20 EMR63889.1 - 1.6e-18 67.8 0.2 3e-18 66.9 0.1 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase PE_PPE_C PF12484.8 EMR63889.1 - 4.8 8.2 7.1 43 5.1 7.1 2.3 1 1 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal HSP70 PF00012.20 EMR63890.1 - 1.7e-05 23.3 0.0 2.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein NTP_transf_7 PF07984.12 EMR63890.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase Cellulase PF00150.18 EMR63891.1 - 4.1e-23 82.2 0.4 1.4e-22 80.5 0.4 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CC2-LZ PF16516.5 EMR63891.1 - 0.002 18.4 4.8 0.002 18.4 4.8 6.1 4 2 1 5 5 5 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FlxA PF14282.6 EMR63891.1 - 0.0089 16.0 48.3 1.2 9.2 0.1 7.4 1 1 5 7 7 7 4 FlxA-like protein HSBP1 PF06825.12 EMR63891.1 - 0.21 11.5 3.2 4.3 7.3 0.4 3.5 3 0 0 3 3 3 0 Heat shock factor binding protein 1 HBB PF06777.11 EMR63891.1 - 0.48 10.1 5.7 5.1 6.7 1.3 3.5 3 1 0 3 3 3 0 Helical and beta-bridge domain TRAF_BIRC3_bd PF16673.5 EMR63891.1 - 1.2 8.9 8.0 38 4.2 1.5 4.8 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF4363 PF14276.6 EMR63891.1 - 1.5 9.0 15.4 7.6 6.7 4.6 4.4 2 1 1 4 4 4 0 Domain of unknown function (DUF4363) YcbB PF08664.10 EMR63891.1 - 1.7 8.7 6.3 0.47 10.5 2.0 2.4 2 0 0 2 2 2 0 YcbB domain Csm2_III-A PF03750.13 EMR63891.1 - 9.6 7.1 9.3 4.5 8.2 3.4 3.1 2 0 0 2 2 2 0 Csm2 Type III-A DUF3439 PF11921.8 EMR63891.1 - 9.8 6.2 6.9 2.1 8.3 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) TRAUB PF08164.12 EMR63892.1 - 1.9e-29 102.0 0.0 1.9e-29 102.0 0.0 3.2 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EMR63892.1 - 4.9e-24 85.6 5.5 4.9e-24 85.6 5.5 3.0 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF5527 PF17665.1 EMR63892.1 - 0.039 13.5 0.1 0.079 12.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Glyco_hydro_16 PF00722.21 EMR63893.1 - 4.7e-16 58.8 0.0 2e-15 56.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EMR63893.1 - 4.7e-05 22.0 1.5 0.0018 16.7 0.5 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) RAMA PF18755.1 EMR63893.1 - 0.26 11.7 2.5 0.29 11.6 0.3 2.1 2 0 0 2 2 2 0 Restriction Enzyme Adenine Methylase Associated Sulfatase PF00884.23 EMR63894.1 - 2.1e-77 260.6 0.0 2.6e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EMR63894.1 - 0.0058 16.9 0.0 0.022 15.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) DUF4994 PF16385.5 EMR63894.1 - 0.02 14.8 0.0 0.049 13.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function Sulfatase_C PF14707.6 EMR63894.1 - 0.038 14.7 0.1 0.55 11.0 0.1 2.5 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Glyco_hydro_72 PF03198.14 EMR63895.1 - 2.5e-112 375.2 4.7 3.5e-112 374.7 4.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EMR63895.1 - 1.1e-21 77.3 6.9 2.6e-21 76.1 6.9 1.7 1 0 0 1 1 1 1 X8 domain Tudor_3 PF18115.1 EMR63896.1 - 2.2e-05 24.2 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EMR63896.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) FlxA PF14282.6 EMR63896.1 - 0.38 10.8 0.0 0.38 10.8 0.0 2.9 3 0 0 3 3 3 0 FlxA-like protein NOA36 PF06524.12 EMR63896.1 - 7.6 5.7 24.9 0.56 9.5 1.6 2.4 2 0 0 2 2 2 0 NOA36 protein ParA PF10609.9 EMR63897.1 - 2.2e-76 256.6 0.8 1.1e-53 182.2 0.0 2.0 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EMR63897.1 - 2e-11 44.0 0.0 1.7e-10 41.0 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMR63897.1 - 8.4e-08 32.3 0.1 7.5e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 EMR63897.1 - 7.5e-05 22.3 0.1 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 EMR63897.1 - 0.00039 19.7 0.4 0.022 13.9 0.1 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 EMR63897.1 - 0.00044 19.6 0.1 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 ATPase MipZ CBP_BcsQ PF06564.12 EMR63897.1 - 0.0017 17.9 0.7 0.045 13.2 0.1 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 EMR63897.1 - 0.0019 18.1 1.2 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMR63897.1 - 0.012 15.2 0.2 0.026 14.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EMR63897.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF2235 PF09994.9 EMR63901.1 - 1.8e-100 336.0 1.1 2.6e-100 335.5 1.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans_2 PF11951.8 EMR63902.1 - 3.7e-06 26.0 0.5 4.9e-06 25.6 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain IstB_IS21 PF01695.17 EMR63903.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NmrA PF05368.13 EMR63904.1 - 9.4e-19 67.9 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR63904.1 - 1e-10 41.8 0.1 6.5e-10 39.2 0.0 2.1 2 1 0 2 2 2 1 NAD(P)H-binding HET PF06985.11 EMR63905.1 - 2.7e-22 79.7 0.0 5.8e-22 78.6 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4072 PF13284.6 EMR63905.1 - 4.6 7.8 10.1 6.4 7.3 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) DUF3632 PF12311.8 EMR63906.1 - 9.4e-11 42.5 0.1 1.2e-10 42.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Alginate_lyase PF05426.12 EMR63907.1 - 2.1e-08 34.1 3.7 5.5e-08 32.7 3.7 1.6 1 1 0 1 1 1 1 Alginate lyase DUF3612 PF12268.8 EMR63907.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) 2OG-FeII_Oxy_3 PF13640.6 EMR63908.1 - 0.0024 18.7 0.0 0.23 12.3 0.0 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DLH PF01738.18 EMR63909.1 - 5.2e-05 22.9 0.0 7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EMR63909.1 - 0.31 10.9 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Securin PF04856.13 EMR63910.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.9 3 1 1 4 4 4 0 Securin sister-chromatid separation inhibitor HET PF06985.11 EMR63911.1 - 1.7e-15 57.7 0.0 1e-10 42.2 0.0 2.6 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 EMR63912.1 - 3.4e-15 56.0 0.0 5.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 EMR63913.1 - 1.2e-31 109.9 0.0 2.9e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR63913.1 - 8.2e-21 74.1 0.7 1.9e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EMR63913.1 - 8.6e-17 61.4 11.6 8.6e-17 61.4 11.6 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Abhydrolase_6 PF12697.7 EMR63914.1 - 7.3e-05 23.5 0.0 8.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family CBM9_2 PF16011.5 EMR63915.1 - 0.00081 19.1 0.2 0.0014 18.4 0.2 1.4 1 1 0 1 1 1 1 Carbohydrate-binding family 9 COX6B PF02297.17 EMR63917.1 - 9.8e-21 73.8 4.7 1.3e-20 73.4 4.7 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.11 EMR63917.1 - 0.0031 17.7 0.1 0.004 17.3 0.1 1.2 1 0 0 1 1 1 1 Prolamin-like SYS1 PF09801.9 EMR63918.1 - 9.9e-51 171.7 4.9 1.1e-50 171.5 4.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Kinocilin PF15033.6 EMR63918.1 - 0.81 9.4 2.9 1 9.0 0.5 2.1 1 1 1 2 2 2 0 Kinocilin protein AAA PF00004.29 EMR63920.1 - 3.2e-19 69.7 0.0 5.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR63920.1 - 2.4e-05 24.8 0.0 3.5e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR63920.1 - 9.3e-05 22.7 0.3 0.00084 19.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain Hydin_ADK PF17213.3 EMR63920.1 - 0.00099 19.4 0.1 0.0017 18.6 0.1 1.4 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_5 PF07728.14 EMR63920.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 EMR63920.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EMR63920.1 - 0.033 14.3 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMR63920.1 - 0.04 13.5 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RuvB_N PF05496.12 EMR63920.1 - 0.05 13.3 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EMR63920.1 - 0.054 14.0 0.0 0.13 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EMR63920.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EMR63920.1 - 0.066 12.8 0.1 1.4 8.5 0.0 2.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Torsin PF06309.11 EMR63920.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin NACHT PF05729.12 EMR63920.1 - 0.09 12.7 0.8 1.2 9.0 0.0 2.7 1 1 2 3 3 3 0 NACHT domain AAA_3 PF07726.11 EMR63920.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EMR63920.1 - 0.1 13.0 0.1 0.35 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 EMR63920.1 - 0.12 12.1 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein HET PF06985.11 EMR63921.1 - 9.4e-26 90.9 0.1 2.1e-25 89.8 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_tran_28_C PF04101.16 EMR63921.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF563 PF04577.14 EMR63922.1 - 2e-32 113.0 0.0 2.9e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF3464 PF11947.8 EMR63922.1 - 0.12 12.1 0.4 0.23 11.2 0.4 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 IPK PF03770.16 EMR63922.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Inositol polyphosphate kinase p450 PF00067.22 EMR63923.1 - 4.8e-32 111.3 0.0 5.8e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.19 EMR63924.1 - 3.2e-24 85.7 6.7 4.4e-23 82.0 6.6 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EMR63924.1 - 3.4e-11 43.2 11.4 1.4e-05 25.0 6.9 2.2 1 1 1 2 2 2 2 Right handed beta helix region Pectate_lyase_3 PF12708.7 EMR63924.1 - 1.3e-05 25.2 8.0 0.00031 20.7 3.8 2.2 1 1 1 2 2 2 2 Pectate lyase superfamily protein Helicase_C PF00271.31 EMR63925.1 - 3.2e-14 53.2 0.0 6.9e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ligase_CoA PF00549.19 EMR63925.1 - 0.069 13.0 0.2 0.6 9.9 0.2 2.1 1 1 0 1 1 1 0 CoA-ligase Choline_transpo PF04515.12 EMR63928.1 - 6.4e-83 278.6 20.9 6.4e-83 278.6 20.9 2.2 2 0 0 2 2 2 2 Plasma-membrane choline transporter Pex14_N PF04695.13 EMR63928.1 - 0.11 13.1 1.4 0.32 11.7 1.4 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UQ_con PF00179.26 EMR63929.1 - 1.6e-52 176.8 0.0 1.8e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMR63929.1 - 0.0048 16.6 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMR63929.1 - 0.037 14.3 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EMR63929.1 - 0.046 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain adh_short PF00106.25 EMR63931.1 - 1.8e-20 73.2 0.0 1.9e-19 69.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR63931.1 - 1e-12 48.1 0.0 6e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR63931.1 - 0.00033 20.6 0.1 0.00059 19.8 0.1 1.3 1 0 0 1 1 1 1 KR domain RdRP PF05183.12 EMR63932.1 - 4.8e-65 220.3 0.0 7.2e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase PIP5K PF01504.18 EMR63933.1 - 3.2e-84 282.4 0.4 5.3e-84 281.7 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PUF PF00806.19 EMR63934.1 - 3e-14 51.8 0.0 0.07 12.9 0.0 6.6 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat Acyl-CoA_dh_N PF02771.16 EMR63935.1 - 6.6e-25 88.0 0.1 1.3e-24 87.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EMR63935.1 - 2.4e-21 76.5 0.5 4.7e-21 75.6 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMR63935.1 - 5.3e-17 61.8 0.0 1.1e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMR63935.1 - 3.1e-06 27.5 0.4 5.3e-06 26.7 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RraB PF06877.11 EMR63937.1 - 0.1 13.4 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Regulator of ribonuclease activity B NAD_binding_4 PF07993.12 EMR63938.1 - 2.8e-33 115.2 0.0 4.1e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EMR63938.1 - 5.9e-14 52.1 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR63938.1 - 2.3e-05 24.7 0.0 0.0001 22.6 0.0 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 EMR63938.1 - 0.00014 21.8 0.8 0.28 11.1 0.0 2.8 3 0 0 3 3 3 2 KR domain GDP_Man_Dehyd PF16363.5 EMR63938.1 - 0.0018 17.7 0.1 0.015 14.7 0.0 2.4 3 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMR63938.1 - 0.019 14.1 0.0 0.98 8.5 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain B12-binding PF02310.19 EMR63938.1 - 0.025 14.6 0.1 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain LPD11 PF18824.1 EMR63938.1 - 0.04 14.0 0.3 3 8.0 0.1 2.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 Polysacc_synt_2 PF02719.15 EMR63938.1 - 0.076 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Dynamin_N PF00350.23 EMR63939.1 - 4.8e-29 101.6 0.0 8.6e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EMR63939.1 - 2.5e-22 79.5 0.0 8.1e-21 74.5 0.0 2.1 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EMR63939.1 - 0.0023 18.0 0.1 0.016 15.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_43 PF04616.14 EMR63940.1 - 5.7e-13 48.8 1.0 9.9e-11 41.5 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Lipoxygenase PF00305.19 EMR63943.1 - 1.3e-18 66.8 0.0 2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase Peptidase_S8 PF00082.22 EMR63944.1 - 4.4e-24 85.3 12.1 1.9e-23 83.2 7.9 2.0 1 1 1 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.16 EMR63944.1 - 1.3e-09 38.6 0.3 3.9e-08 33.8 0.3 2.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 Asp PF00026.23 EMR63945.1 - 8.3e-05 22.2 0.1 0.00074 19.0 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease EGF_2 PF07974.13 EMR63946.1 - 0.00037 20.8 10.3 0.00064 20.0 10.3 1.4 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 EMR63946.1 - 0.022 15.0 4.5 0.038 14.3 4.5 1.3 1 0 0 1 1 1 0 EB module hEGF PF12661.7 EMR63946.1 - 0.047 14.4 6.4 0.1 13.3 6.4 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF Glyco_hydro_43 PF04616.14 EMR63946.1 - 0.065 12.5 4.3 0.12 11.7 0.3 2.7 1 1 2 3 3 3 0 Glycosyl hydrolases family 43 EGF_Tenascin PF18720.1 EMR63946.1 - 1.4 9.0 7.6 3.2 7.9 7.6 1.6 1 0 0 1 1 1 0 Tenascin EGF domain Squash PF00299.18 EMR63946.1 - 4.5 7.4 7.3 12 6.0 7.3 1.7 1 1 0 1 1 1 0 Squash family serine protease inhibitor Lactonase PF10282.9 EMR63947.1 - 5.9e-40 137.6 0.0 7.4e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Subtilosin_A PF11420.8 EMR63947.1 - 4 7.5 10.9 13 5.9 0.1 3.4 3 0 0 3 3 3 0 Bacteriocin subtilosin A Amidase PF01425.21 EMR63948.1 - 9.9e-48 163.2 0.1 2.5e-45 155.3 0.2 2.2 2 0 0 2 2 2 2 Amidase XFP_N PF09364.10 EMR63949.1 - 1e-141 472.0 0.0 1.4e-141 471.6 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 EMR63949.1 - 9.3e-81 269.7 0.0 1.6e-80 268.9 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 EMR63949.1 - 3.2e-60 203.1 0.6 1.1e-59 201.3 0.0 2.0 2 1 1 3 3 3 1 XFP C-terminal domain PRANC PF09372.10 EMR63950.1 - 0.085 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 PRANC domain DUF1348 PF07080.11 EMR63951.1 - 2.8e-64 214.9 8.3 3.3e-64 214.6 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EMR63951.1 - 5.9e-08 33.3 2.8 8.1e-08 32.8 2.8 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EMR63951.1 - 1.1e-05 25.8 0.4 1.6e-05 25.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 EMR63951.1 - 0.025 14.4 0.1 0.044 13.6 0.1 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Ribosomal_L24e PF01246.20 EMR63952.1 - 9.8e-19 67.4 0.2 2.6e-18 66.0 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e DUF775 PF05603.12 EMR63952.1 - 0.023 14.2 1.2 0.03 13.9 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) CMS1 PF14617.6 EMR63953.1 - 1.5e-51 175.2 0.1 2.5e-51 174.5 0.1 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EMR63953.1 - 9.1e-06 25.6 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AKAP_110 PF05716.13 EMR63953.1 - 0.052 11.8 0.0 0.071 11.3 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Redoxin PF08534.10 EMR63954.1 - 2.3e-36 124.7 0.0 2.6e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMR63954.1 - 1.8e-08 34.4 0.0 2.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family RGS PF00615.19 EMR63955.1 - 8.2e-06 26.1 0.1 0.002 18.4 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Dak1 PF02733.17 EMR63956.1 - 2.2e-97 325.7 0.0 3e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EMR63956.1 - 2.3e-38 131.8 2.4 4.5e-38 130.9 2.4 1.5 1 0 0 1 1 1 1 DAK2 domain F_bP_aldolase PF01116.20 EMR63957.1 - 1.1e-86 290.8 0.2 1.3e-86 290.6 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_11 PF14833.6 EMR63958.1 - 1.5e-38 131.8 0.2 5.3e-25 88.0 0.0 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EMR63958.1 - 3.5e-32 111.8 0.1 1e-31 110.3 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMR63958.1 - 0.00043 20.8 0.0 0.0048 17.5 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EMR63958.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EMR63958.1 - 0.0021 18.0 0.1 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMR63958.1 - 0.056 13.0 0.0 0.49 10.0 0.0 2.4 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATG16 PF08614.11 EMR63959.1 - 0.002 18.4 1.4 0.0022 18.2 0.1 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Spore_Cse60 PF10957.8 EMR63959.1 - 0.043 13.8 1.9 0.1 12.6 0.4 2.3 2 0 0 2 2 2 0 Sporulation protein Cse60 ING PF12998.7 EMR63959.1 - 0.19 12.4 2.4 18 6.0 0.2 2.9 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding PepX_C PF08530.10 EMR63960.1 - 9.5e-26 91.1 0.6 1.3e-25 90.7 0.6 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EMR63960.1 - 1.8e-08 34.3 0.2 0.006 16.2 0.1 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DNA_ligase_A_C PF04679.15 EMR63960.1 - 0.013 16.0 0.2 0.037 14.6 0.2 1.7 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region LacAB_rpiB PF02502.18 EMR63961.1 - 1.8e-41 141.4 0.2 2e-41 141.3 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase KptA_kDCL PF18176.1 EMR63961.1 - 0.04 13.8 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain MIT PF04212.18 EMR63964.1 - 6.1e-17 61.5 1.6 1.3e-16 60.4 1.6 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Adaptin_binding PF10199.9 EMR63964.1 - 0.053 14.1 0.7 0.92 10.1 0.3 2.8 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Sporozoite_P67 PF05642.11 EMR63964.1 - 2.5 6.1 6.7 0.11 10.6 0.1 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen TPR_MLP1_2 PF07926.12 EMR63965.1 - 0.00016 21.7 16.7 0.00016 21.7 16.7 4.0 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EMR63965.1 - 0.0017 17.3 15.0 0.0017 17.3 15.0 3.2 1 1 2 3 3 3 1 Spc7 kinetochore protein Vps53_N PF04100.12 EMR63965.1 - 0.0052 15.8 4.4 0.0052 15.8 4.4 3.3 1 1 1 3 3 3 1 Vps53-like, N-terminal SCO1-SenC PF02630.14 EMR63965.1 - 0.0096 15.8 5.7 0.94 9.4 0.5 3.1 1 1 1 2 2 2 2 SCO1/SenC GAS PF13851.6 EMR63965.1 - 0.012 15.0 61.7 0.039 13.3 23.4 4.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 EMR63965.1 - 0.59 9.5 65.4 1 8.8 43.5 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3562 PF12085.8 EMR63965.1 - 0.87 9.2 8.4 4.7 6.9 0.1 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3562) DUF4472 PF14739.6 EMR63965.1 - 1.7 9.4 55.9 0.096 13.4 16.4 4.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4472) TMF_TATA_bd PF12325.8 EMR63965.1 - 2.6 8.3 63.2 2.4 8.4 8.5 5.7 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EMR63965.1 - 5.6 7.5 76.4 0.37 11.3 24.6 4.9 1 1 4 5 5 5 0 Apg6 coiled-coil region Lipase_GDSL PF00657.22 EMR63966.1 - 0.00052 20.0 0.0 0.0006 19.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EMR63966.1 - 0.15 12.4 0.5 0.64 10.4 0.5 2.0 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 EMR63967.1 - 1.3e-12 47.4 13.4 1.3e-12 47.4 13.4 3.1 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR63967.1 - 3.2e-09 35.8 15.6 4.7e-05 22.0 2.7 3.0 2 1 1 3 3 3 3 Fungal trichothecene efflux pump (TRI12) Transp_inhibit PF18791.1 EMR63967.1 - 0.21 11.1 0.5 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain MethyTransf_Reg PF10119.9 EMR63968.1 - 0.14 12.9 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain FAD_binding_3 PF01494.19 EMR63969.1 - 3.7e-63 213.9 0.0 5.1e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF1989 PF09347.10 EMR63969.1 - 3.3e-47 160.2 0.0 2.4e-45 154.1 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.21 EMR63969.1 - 4.5e-17 62.1 0.0 9.2e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DAO PF01266.24 EMR63969.1 - 2.7e-05 23.9 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF2334 PF10096.9 EMR63969.1 - 5.8e-05 22.8 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Pyr_redox_3 PF13738.6 EMR63969.1 - 0.00025 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.12 EMR63969.1 - 0.00036 20.6 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 EMR63969.1 - 0.00056 20.1 0.3 0.0022 18.2 0.1 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR63969.1 - 0.00073 18.9 0.1 0.0064 15.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR63969.1 - 0.0012 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EMR63969.1 - 0.0017 17.3 0.0 0.0055 15.6 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 EMR63969.1 - 0.0025 18.3 0.0 0.0055 17.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR63969.1 - 0.0047 16.0 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR63969.1 - 0.0051 15.9 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMR63969.1 - 0.0086 14.8 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein DUF445 PF04286.12 EMR63970.1 - 0.014 15.2 0.6 0.014 15.2 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Prominin PF05478.11 EMR63970.1 - 0.27 9.1 6.4 0.35 8.8 6.4 1.2 1 0 0 1 1 1 0 Prominin Herpes_UL6 PF01763.16 EMR63970.1 - 0.32 9.4 11.8 0.21 10.1 0.3 2.2 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF4192 PF13830.6 EMR63970.1 - 4 7.4 12.9 0.5 10.4 7.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Helicase_C PF00271.31 EMR63971.1 - 0.00063 20.1 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TIM PF00121.18 EMR63975.1 - 1.2e-44 152.5 0.0 5.2e-43 147.2 0.0 2.3 1 1 0 1 1 1 1 Triosephosphate isomerase DUF2103 PF09876.9 EMR63976.1 - 0.062 13.3 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2103) B12-binding PF02310.19 EMR63976.1 - 0.062 13.3 0.1 0.12 12.5 0.1 1.5 1 1 0 1 1 1 0 B12 binding domain Glyco_hydro_61 PF03443.14 EMR63978.1 - 6.2e-13 49.1 0.0 1.8e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.19 EMR63979.1 - 1.1e-54 186.0 0.0 1.5e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain RNA_ligase PF09414.10 EMR63980.1 - 9.9e-29 100.7 0.0 2.7e-28 99.3 0.0 1.6 2 0 0 2 2 2 1 RNA ligase Fungal_trans_2 PF11951.8 EMR63981.1 - 0.00012 21.0 0.6 0.014 14.2 0.1 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Ribosomal_60s PF00428.19 EMR63981.1 - 0.021 15.4 13.0 0.059 14.0 13.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein K_channel_TID PF07941.11 EMR63981.1 - 0.027 14.9 6.9 0.059 13.8 6.9 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RskA PF10099.9 EMR63981.1 - 0.27 11.5 5.5 0.071 13.4 0.9 2.2 2 1 1 3 3 3 0 Anti-sigma-K factor rskA UQ_con PF00179.26 EMR63982.1 - 2e-27 95.6 0.1 2.6e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MFS_1 PF07690.16 EMR63983.1 - 3.6e-18 65.6 23.0 1.6e-16 60.2 23.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR63983.1 - 0.014 15.2 0.9 0.054 13.2 0.9 2.0 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 DUF2070 PF09843.9 EMR63983.1 - 0.13 10.5 2.3 0.2 9.9 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3084 PF11283.8 EMR63984.1 - 0.045 13.7 1.1 0.045 13.7 1.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3084) DUF572 PF04502.13 EMR63985.1 - 7.3e-66 223.1 0.0 8.9e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) ABC2_membrane PF01061.24 EMR63986.1 - 1.4e-93 312.1 65.1 1.6e-50 171.5 21.5 3.5 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EMR63986.1 - 1e-33 116.8 0.0 1.3e-16 61.3 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EMR63986.1 - 9.1e-32 108.8 20.4 2.2e-31 107.6 0.5 4.2 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 EMR63986.1 - 2.8e-16 59.9 0.5 8.7e-16 58.3 0.5 1.9 1 1 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 EMR63986.1 - 9.7e-07 29.0 0.1 0.014 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMR63986.1 - 1.8e-06 28.5 0.2 0.00032 21.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EMR63986.1 - 3.6e-06 26.7 0.2 0.00015 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMR63986.1 - 2.1e-05 24.5 0.3 0.00064 19.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EMR63986.1 - 5e-05 23.2 0.1 0.4 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMR63986.1 - 6.6e-05 22.6 0.4 0.0023 17.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMR63986.1 - 0.00021 21.8 0.1 0.0069 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EMR63986.1 - 0.00058 19.1 50.6 0.0015 17.7 14.6 3.9 3 2 0 3 3 3 2 ABC-2 family transporter protein AAA_22 PF13401.6 EMR63986.1 - 0.00085 19.6 0.1 0.42 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EMR63986.1 - 0.00091 18.9 1.1 0.088 12.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EMR63986.1 - 0.002 17.6 0.0 1.3 8.4 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EMR63986.1 - 0.0099 15.6 0.5 0.68 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMR63986.1 - 0.011 15.6 0.4 0.63 9.9 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EMR63986.1 - 0.023 15.2 0.0 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EMR63986.1 - 0.034 13.9 0.8 6.8 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMR63986.1 - 0.035 14.3 0.5 0.5 10.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMR63986.1 - 0.037 14.4 0.2 9.8 6.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EMR63986.1 - 0.039 14.4 0.1 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EMR63986.1 - 0.071 12.8 0.1 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 EMR63986.1 - 0.095 12.6 0.0 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_19 PF13245.6 EMR63986.1 - 0.88 9.9 2.2 5.7 7.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Beta-lactamase PF00144.24 EMR63987.1 - 1.4e-32 113.3 0.0 2.4e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_7 PF00840.20 EMR63988.1 - 1.3e-141 472.3 9.1 1.6e-141 472.0 9.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 TAT_signal PF10518.9 EMR63988.1 - 0.47 10.4 3.4 1.1 9.3 3.4 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Cyclase PF04199.13 EMR63989.1 - 1.4e-18 67.5 0.2 1.9e-18 67.0 0.2 1.2 1 0 0 1 1 1 1 Putative cyclase AvrB_AvrC PF05394.11 EMR63989.1 - 0.025 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Avirulence protein DUF1835 PF08874.10 EMR63989.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) DOPA_dioxygen PF08883.11 EMR63990.1 - 1.2e-42 144.4 0.1 1.6e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family GFA PF04828.14 EMR63991.1 - 1.4e-24 86.2 0.0 1.8e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aldedh PF00171.22 EMR63992.1 - 1.5e-146 488.6 0.0 1.7e-146 488.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.22 EMR63993.1 - 2.8e-41 141.7 0.0 3.4e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CK_II_beta PF01214.18 EMR63994.1 - 1.1e-75 253.5 0.0 2.9e-75 252.1 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Myc_N PF01056.18 EMR63994.1 - 0.27 11.1 1.5 0.45 10.4 1.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Spt5_N PF11942.8 EMR63994.1 - 1.2 10.2 15.8 0.45 11.5 8.5 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.6 EMR63994.1 - 4.4 7.7 14.4 7.3 7.0 3.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box-like PF12937.7 EMR63995.1 - 3.3e-07 30.1 0.1 6e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR63995.1 - 0.0014 18.4 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain YL1 PF05764.13 EMR63995.1 - 0.0024 18.1 2.3 0.0024 18.1 2.3 2.0 2 0 0 2 2 2 1 YL1 nuclear protein Cnd2 PF05786.14 EMR63995.1 - 0.0045 15.7 6.5 0.0095 14.7 6.5 1.5 1 0 0 1 1 1 1 Condensin complex subunit 2 HSP90 PF00183.18 EMR63995.1 - 0.43 9.4 1.9 0.63 8.9 1.9 1.1 1 0 0 1 1 1 0 Hsp90 protein RNA_polI_A34 PF08208.11 EMR63995.1 - 0.95 9.5 7.8 1.8 8.6 7.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.12 EMR63995.1 - 5.4 5.1 9.7 5.9 5.0 8.3 1.6 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 EMR63995.1 - 5.8 6.2 12.7 0.019 14.4 2.2 2.0 2 0 0 2 2 2 0 SDA1 ABC2_membrane PF01061.24 EMR63996.1 - 2.2e-74 249.4 56.7 2.4e-38 131.7 23.9 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EMR63996.1 - 1.9e-35 122.4 0.0 1.8e-16 60.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EMR63996.1 - 3.3e-26 91.0 5.2 4.6e-23 80.9 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EMR63996.1 - 3.2e-19 69.3 0.1 3e-18 66.2 0.0 2.7 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_21 PF13304.6 EMR63996.1 - 1.5e-06 28.2 0.0 0.19 11.5 0.0 3.4 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EMR63996.1 - 1.5e-05 25.2 0.0 0.013 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EMR63996.1 - 1.8e-05 25.2 0.6 0.079 13.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EMR63996.1 - 3.4e-05 23.5 0.4 0.031 13.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMR63996.1 - 4.5e-05 23.9 0.1 0.093 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EMR63996.1 - 0.00011 21.9 0.3 0.012 15.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMR63996.1 - 0.00011 22.8 0.0 0.02 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMR63996.1 - 0.00046 20.5 0.1 0.058 13.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EMR63996.1 - 0.0008 19.3 0.0 0.0076 16.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 EMR63996.1 - 0.0011 18.1 18.0 0.0011 18.1 18.0 2.4 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_22 PF13401.6 EMR63996.1 - 0.0037 17.5 0.1 0.38 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 EMR63996.1 - 0.0043 16.4 0.0 0.088 12.1 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain cobW PF02492.19 EMR63996.1 - 0.0062 16.1 0.9 0.21 11.2 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EMR63996.1 - 0.0063 16.0 0.0 0.69 9.3 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EMR63996.1 - 0.0071 16.3 0.3 4.5 7.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 EMR63996.1 - 0.023 14.4 1.2 1.7 8.3 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMR63996.1 - 0.043 14.2 0.0 12 6.4 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Mor PF08765.11 EMR63996.1 - 0.09 12.8 0.0 0.96 9.5 0.0 2.4 2 0 0 2 2 2 0 Mor transcription activator family Wzz PF02706.15 EMR63996.1 - 0.28 11.5 2.0 1.6 9.1 0.0 3.0 3 0 0 3 3 3 0 Chain length determinant protein AAA_23 PF13476.6 EMR63996.1 - 0.43 11.1 0.1 0.43 11.1 0.1 2.2 3 0 0 3 3 1 0 AAA domain FMO-like PF00743.19 EMR63997.1 - 4.1e-14 51.9 0.0 2.1e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR63997.1 - 4.6e-13 49.1 0.0 1.4e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR63997.1 - 5.9e-12 45.4 0.1 9.3e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMR63997.1 - 6.3e-06 25.6 0.0 2.3e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.6 EMR63997.1 - 0.0085 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) Peptidase_M64 PF09471.10 EMR63999.1 - 1.5e-18 67.3 0.0 1e-10 41.7 0.0 2.8 1 1 1 2 2 2 2 IgA Peptidase M64 DUF2970 PF11174.8 EMR64000.1 - 0.05 13.5 0.1 0.05 13.5 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) Tom7 PF08038.12 EMR64001.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 TOM7 family PTPRCAP PF15713.5 EMR64001.1 - 1.5 9.1 17.2 1.3 9.3 2.7 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated AT_hook PF02178.19 EMR64001.1 - 2.4 8.3 14.9 1.4 9.0 8.2 2.7 2 0 0 2 2 2 0 AT hook motif CDC45 PF02724.14 EMR64001.1 - 4.5 5.4 10.1 0.4 8.9 1.7 2.0 2 0 0 2 2 2 0 CDC45-like protein GEN1_C PF18380.1 EMR64001.1 - 9.5 7.2 9.4 15 6.5 3.8 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Pro_isomerase PF00160.21 EMR64002.1 - 1.2e-50 171.8 0.0 1.4e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf_UBZ PF18439.1 EMR64003.1 - 0.2 11.3 2.3 2.2 7.9 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 EMR64003.1 - 1 9.0 7.9 0.19 11.3 3.1 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Acyl_transf_3 PF01757.22 EMR64004.1 - 5.1e-21 75.1 17.5 7.9e-21 74.5 17.5 1.3 1 0 0 1 1 1 1 Acyltransferase family TFIIS_C PF01096.18 EMR64005.1 - 4.3e-19 68.1 1.0 4.3e-19 68.1 1.0 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EMR64005.1 - 0.00039 20.2 0.5 0.0069 16.2 0.1 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.13 EMR64005.1 - 0.017 15.1 0.4 5.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_12 PF17976.1 EMR64005.1 - 0.097 13.0 4.6 0.11 12.8 0.1 2.5 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain CN_hydrolase PF00795.22 EMR64006.1 - 1.2e-27 96.9 0.0 1.4e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Med31 PF05669.12 EMR64009.1 - 7.5e-37 125.2 5.6 8.4e-37 125.1 5.6 1.0 1 0 0 1 1 1 1 SOH1 SMC_N PF02463.19 EMR64010.1 - 2.8e-25 89.1 0.0 1.2e-24 87.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMR64010.1 - 6.5e-20 72.5 2.0 6.5e-20 72.5 2.0 5.5 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.6 EMR64010.1 - 9e-06 25.7 1.1 0.025 14.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMR64010.1 - 0.00047 20.0 10.3 0.00047 20.0 10.3 4.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMR64010.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EMR64010.1 - 0.038 14.4 0.0 0.56 10.6 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EMR64010.1 - 0.069 13.0 5.3 0.7 9.8 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase AAA_27 PF13514.6 EMR64010.1 - 0.38 10.3 0.0 0.38 10.3 0.0 4.5 4 2 1 5 5 5 0 AAA domain AAA_22 PF13401.6 EMR64010.1 - 2 8.7 5.4 20 5.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain BLOC1_2 PF10046.9 EMR64010.1 - 5.9 7.3 42.8 3.7 7.9 0.2 7.1 6 1 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Acetyltransf_1 PF00583.25 EMR64011.1 - 0.00015 22.0 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR64011.1 - 0.092 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EMR64012.1 - 1.3e-30 106.6 27.4 1.3e-30 106.6 27.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily AA_permease_2 PF13520.6 EMR64013.1 - 1.8e-49 168.7 51.3 2.1e-36 125.7 34.1 2.0 2 0 0 2 2 2 2 Amino acid permease Peptidase_A22B PF04258.13 EMR64014.1 - 3.3e-55 187.6 9.1 3.8e-38 131.7 2.6 2.2 2 0 0 2 2 2 2 Signal peptide peptidase DEC-1_C PF04626.13 EMR64014.1 - 0.11 12.9 2.8 0.18 12.2 2.8 1.3 1 0 0 1 1 1 0 Dec-1 protein, C terminal region YqhR PF11085.8 EMR64014.1 - 5.6 6.9 9.0 1.2 9.0 4.9 2.0 2 0 0 2 2 2 0 Conserved membrane protein YqhR Ank_3 PF13606.6 EMR64015.1 - 1.5e-08 34.2 0.3 0.03 14.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EMR64015.1 - 4.9e-07 30.2 0.3 1e-06 29.3 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR64015.1 - 2.7e-06 27.8 0.1 0.00011 22.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR64015.1 - 2.6e-05 24.4 1.6 0.14 12.6 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EMR64015.1 - 0.00094 19.5 0.8 0.19 12.2 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat NOA36 PF06524.12 EMR64015.1 - 0.61 9.4 5.5 0.89 8.8 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein Lyase_1 PF00206.20 EMR64016.1 - 2.8e-110 368.6 0.0 3.9e-110 368.1 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EMR64016.1 - 1.2e-21 76.9 0.0 3.3e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus HET PF06985.11 EMR64018.1 - 2.9e-29 102.3 0.6 2.9e-29 102.3 0.6 2.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Malate_synthase PF01274.22 EMR64019.1 - 2e-228 758.9 0.0 2.3e-228 758.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HSP70 PF00012.20 EMR64020.1 - 4e-10 38.5 0.3 4.1e-09 35.2 0.1 1.9 2 0 0 2 2 2 2 Hsp70 protein Hexokinase_1 PF00349.21 EMR64021.1 - 2.6e-76 256.0 0.0 3.7e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EMR64021.1 - 1.2e-75 254.0 0.0 1.6e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase HHH_5 PF14520.6 EMR64021.1 - 0.058 14.0 3.2 1.8 9.2 0.2 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH PF00633.23 EMR64021.1 - 0.25 11.3 0.9 8.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sugar_tr PF00083.24 EMR64022.1 - 1.4e-84 284.6 20.9 3e-45 155.0 5.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR64022.1 - 5.4e-28 97.9 35.0 3.6e-26 91.9 27.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR64022.1 - 3.5e-06 25.7 4.0 3.5e-06 25.7 4.0 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EMR64022.1 - 2.9 7.1 28.5 0.011 15.0 8.3 2.9 3 0 0 3 3 3 0 Uncharacterised MFS-type transporter YbfB Fringe PF02434.16 EMR64023.1 - 2.4e-08 33.7 0.1 8.1e-07 28.7 0.1 2.2 1 1 0 1 1 1 1 Fringe-like Glyco_transf_92 PF01697.27 EMR64023.1 - 0.011 15.4 0.9 0.019 14.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 92 DUF604 PF04646.12 EMR64023.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Hexapep PF00132.24 EMR64024.1 - 6.1e-08 32.1 8.2 0.00016 21.3 2.3 4.2 3 1 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMR64024.1 - 0.0022 17.7 6.4 0.0044 16.7 0.8 2.9 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EMR64024.1 - 0.16 10.9 0.0 0.35 9.7 0.0 1.4 1 1 0 1 1 1 0 L-fucokinase 4HBT_2 PF13279.6 EMR64025.1 - 3.4e-07 30.8 0.0 5.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily FliT PF05400.13 EMR64026.1 - 0.049 14.5 0.3 0.049 14.5 0.3 1.6 2 0 0 2 2 2 0 Flagellar protein FliT Glyco_hydro_43 PF04616.14 EMR64028.1 - 1.6e-21 76.9 0.3 2.4e-21 76.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EMR64028.1 - 5.2e-15 55.7 1.1 2.6e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Beta xylosidase C-terminal Concanavalin A-like domain Abhydrolase_3 PF07859.13 EMR64029.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold CFEM PF05730.11 EMR64030.1 - 1.1e-10 41.5 13.9 1.8e-10 40.8 13.9 1.4 1 0 0 1 1 1 1 CFEM domain EcKinase PF02958.20 EMR64032.1 - 6.8e-18 65.0 0.0 1.6e-15 57.2 0.0 2.2 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EMR64032.1 - 1e-09 37.8 0.0 9.4e-09 34.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) APH PF01636.23 EMR64032.1 - 3e-08 33.9 0.1 3.9e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EMR64032.1 - 0.00045 19.5 0.0 0.26 10.4 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase GTP_cyclohydro2 PF00925.20 EMR64033.1 - 8e-59 197.9 0.0 9.9e-59 197.6 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II COesterase PF00135.28 EMR64034.1 - 2.5e-48 165.2 0.0 1.6e-39 136.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR64034.1 - 2.8e-08 33.9 0.0 4.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR64034.1 - 0.027 15.1 3.7 0.14 12.7 3.7 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Arf PF00025.21 EMR64035.1 - 7e-74 247.0 0.4 8.2e-74 246.8 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMR64035.1 - 1.7e-14 54.1 0.1 2.3e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EMR64035.1 - 3.6e-13 49.4 2.3 2.2e-09 37.0 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EMR64035.1 - 3.8e-13 49.4 0.0 4.4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EMR64035.1 - 2e-12 46.9 0.1 2.5e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EMR64035.1 - 1.4e-10 40.9 0.1 1.7e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMR64035.1 - 0.00021 21.3 0.1 0.00028 20.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EMR64035.1 - 0.033 13.5 0.2 0.068 12.5 0.2 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Methyltrn_RNA_3 PF02598.17 EMR64035.1 - 0.034 13.7 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase CRISPR_Cas2 PF09827.9 EMR64035.1 - 0.061 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 p450 PF00067.22 EMR64036.1 - 1.4e-59 202.1 0.0 1.9e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PMI_typeI PF01238.21 EMR64037.1 - 1.5e-140 468.7 0.0 1.7e-140 468.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I RRM_1 PF00076.22 EMR64038.1 - 1.9e-14 53.3 0.0 3.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 EMR64038.1 - 1.2e-10 41.9 0.0 2.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NDUF_B7 PF05676.13 EMR64039.1 - 2.6e-29 100.7 4.9 3e-29 100.5 4.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EMR64039.1 - 0.0082 16.1 1.8 0.012 15.6 1.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like YqhR PF11085.8 EMR64040.1 - 0.086 12.8 3.8 0.069 13.1 1.9 1.8 2 1 0 2 2 2 0 Conserved membrane protein YqhR zf-C2H2_4 PF13894.6 EMR64041.1 - 0.047 14.5 0.1 0.076 13.9 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Pkinase PF00069.25 EMR64043.1 - 2.6e-64 217.1 0.0 4.6e-64 216.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64043.1 - 2.3e-30 105.7 0.0 3.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR64043.1 - 0.002 17.5 0.1 0.0044 16.4 0.1 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EMR64043.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EMR64043.1 - 0.081 12.8 0.0 0.23 11.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RPA43_OB PF17875.1 EMR64044.1 - 1.8e-38 131.9 0.2 1.8e-38 131.9 0.2 3.3 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EMR64044.1 - 0.00084 19.7 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RR_TM4-6 PF06459.12 EMR64044.1 - 3.1 7.6 25.5 1.4 8.7 18.1 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NmrA PF05368.13 EMR64045.1 - 4.9e-30 104.8 0.0 6e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR64045.1 - 1.3e-11 44.8 0.0 7.8e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EMR64045.1 - 6.5e-07 29.0 0.0 6.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR64045.1 - 0.00017 20.7 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EMR64045.1 - 0.0049 16.8 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR64045.1 - 0.0052 16.0 0.0 0.0077 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EMR64045.1 - 0.024 15.1 0.0 0.065 13.7 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EMR64045.1 - 0.097 12.0 0.0 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase YGGT PF02325.17 EMR64045.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 YGGT family Actin PF00022.19 EMR64046.1 - 6.2e-111 370.9 0.0 3.9e-110 368.3 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EMR64046.1 - 0.03 13.2 0.0 0.17 10.6 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein GD_N PF16030.5 EMR64047.1 - 0.048 14.0 0.1 0.056 13.8 0.1 1.1 1 0 0 1 1 1 0 Serine protease gd N-terminus DUF1325 PF07039.11 EMR64048.1 - 5.7e-29 100.9 1.7 4.8e-28 97.9 0.1 2.6 2 0 0 2 2 2 1 SGF29 tudor-like domain Neisseria_TspB PF05616.13 EMR64049.1 - 0.15 10.5 0.9 0.25 9.8 0.9 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein FAD_binding_3 PF01494.19 EMR64050.1 - 2.1e-15 56.8 0.1 1.7e-07 30.9 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMR64050.1 - 0.00032 20.9 0.0 0.0012 19.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR64050.1 - 0.0047 16.2 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR64050.1 - 0.028 14.0 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR64050.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR64050.1 - 0.064 13.8 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NACHT PF05729.12 EMR64051.1 - 1.2e-08 35.0 0.0 2.2e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMR64051.1 - 0.00038 20.9 0.0 0.00079 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EMR64051.1 - 0.015 15.8 0.1 0.059 13.8 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EMR64051.1 - 0.019 14.1 0.0 0.05 12.8 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EMR64051.1 - 0.071 13.7 0.1 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMR64051.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Peptidase_S28 PF05577.12 EMR64052.1 - 2.6e-46 158.3 4.5 2.8e-35 122.0 0.3 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Oxidored_FMN PF00724.20 EMR64053.1 - 1.6e-41 142.7 0.0 2.1e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF561 PF04481.12 EMR64053.1 - 0.24 10.6 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Dus PF01207.17 EMR64053.1 - 0.25 10.4 0.1 1.3 8.1 0.0 2.1 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) EF-hand_7 PF13499.6 EMR64054.1 - 4.9e-11 42.9 0.0 1.4e-06 28.7 0.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EMR64054.1 - 9.1e-11 40.5 0.4 0.053 13.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EMR64054.1 - 1.9e-09 36.7 1.4 0.12 12.4 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EMR64054.1 - 0.0025 17.2 1.7 16 5.2 0.0 4.1 4 0 0 4 4 4 2 EF hand S-l_SbsC_C PF18316.1 EMR64054.1 - 0.033 14.7 0.1 0.057 13.9 0.1 1.3 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain Glyco_transf_90 PF05686.12 EMR64055.1 - 1.5e-10 40.5 0.0 1.2e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 90 DUF4667 PF15700.5 EMR64055.1 - 8.1e-05 22.8 13.5 0.068 13.3 0.1 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4667) SR-25 PF10500.9 EMR64055.1 - 0.00054 19.7 43.9 0.0084 15.7 9.1 3.5 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein BSP_II PF05432.11 EMR64055.1 - 0.017 14.8 6.4 0.036 13.8 6.4 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3446 PF11928.8 EMR64055.1 - 0.022 15.1 37.3 0.2 12.0 8.2 3.7 4 0 0 4 4 4 0 Early growth response N-terminal domain PcfK PF14058.6 EMR64055.1 - 3.8 7.8 7.7 6.7 7.0 7.7 1.2 1 0 0 1 1 1 0 PcfK-like protein dCMP_cyt_deam_1 PF00383.23 EMR64056.1 - 1e-23 83.1 1.8 1.5e-23 82.6 1.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMR64056.1 - 2.4e-06 27.3 0.1 3.9e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 EMR64056.1 - 0.0012 19.4 0.0 0.0043 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMR64056.1 - 0.02 15.1 0.1 0.042 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TT1725 PF18324.1 EMR64056.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein TT1725 zinc_ribbon_2 PF13240.6 EMR64057.1 - 0.039 13.7 0.1 0.095 12.4 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_2 PF13639.6 EMR64057.1 - 0.04 14.3 7.1 0.087 13.2 7.1 1.6 1 1 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 EMR64057.1 - 0.088 12.9 2.1 0.18 11.9 2.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EMR64057.1 - 0.15 12.3 2.9 0.34 11.1 2.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1993 PF09351.10 EMR64058.1 - 7.5e-48 162.7 0.0 8.4e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Proteasome PF00227.26 EMR64060.1 - 1.5e-47 161.5 0.0 2.2e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMR64060.1 - 4.2e-12 45.5 1.5 5e-12 45.3 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2011 PF09428.10 EMR64061.1 - 0.0072 16.5 0.2 0.12 12.6 0.0 2.1 1 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) SIS PF01380.22 EMR64062.1 - 9.2e-14 51.4 0.0 3.2e-13 49.7 0.0 1.9 2 1 0 2 2 2 1 SIS domain DUF3694 PF12473.8 EMR64063.1 - 4.6e-52 176.8 0.0 1.5e-51 175.0 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein Kinesin PF00225.23 EMR64063.1 - 3e-51 174.3 0.5 6.1e-51 173.3 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 EMR64063.1 - 7.7e-36 123.9 9.8 1.2e-30 107.0 0.3 3.4 2 1 1 3 3 3 2 Kinesin-associated KIF1B PF12423.8 EMR64063.1 - 5.1e-07 30.0 0.7 1.8e-06 28.3 0.7 2.0 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.29 EMR64063.1 - 0.043 14.3 0.0 1.5 9.4 0.0 2.9 1 1 0 1 1 1 0 PH domain DUF5336 PF17270.2 EMR64064.1 - 0.08 12.6 0.5 0.18 11.4 0.1 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5336) Claudin_2 PF13903.6 EMR64064.1 - 0.23 11.2 0.0 0.23 11.2 0.0 2.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF997 PF06196.12 EMR64064.1 - 0.66 10.0 7.1 0.56 10.2 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF997) Cyt-b5 PF00173.28 EMR64065.1 - 8.9e-20 70.6 0.2 9.9e-20 70.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.12 EMR64065.1 - 0.092 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain V-ATPase_H_C PF11698.8 EMR64065.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.5 1 1 0 1 1 1 0 V-ATPase subunit H DUF2373 PF10180.9 EMR64066.1 - 2e-19 69.2 0.0 3.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) adh_short PF00106.25 EMR64067.1 - 4.3e-20 72.0 0.0 5.5e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64067.1 - 2.1e-18 66.7 0.0 2.6e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR64067.1 - 0.0058 16.1 0.0 0.0078 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMR64067.1 - 0.008 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF3978 PF13123.6 EMR64067.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) p450 PF00067.22 EMR64068.1 - 6.9e-48 163.5 0.0 9.3e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3040 PF11239.8 EMR64068.1 - 1.5 9.1 4.6 3.2 8.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Glyco_hydro_16 PF00722.21 EMR64069.1 - 7e-05 22.4 0.1 0.00028 20.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Phage_capsid PF05065.13 EMR64069.1 - 2.4 7.4 8.9 0.6 9.4 2.7 2.8 3 0 0 3 3 3 0 Phage capsid family Leuk-A4-hydro_C PF09127.11 EMR64070.1 - 9.4e-33 112.7 0.0 2.5e-32 111.3 0.0 1.8 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EMR64070.1 - 2.3e-32 112.7 0.0 7.7e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EMR64070.1 - 5.5e-20 71.9 0.4 1.2e-17 64.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase family M1 domain Mrx7 PF10906.8 EMR64070.1 - 0.024 14.9 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 MIOREX complex component 7 MFS_1 PF07690.16 EMR64072.1 - 1.9e-28 99.4 31.6 1.9e-28 99.4 31.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR64072.1 - 2.3e-20 72.9 19.9 9.9e-17 60.9 5.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter ATG7_N PF16420.5 EMR64073.1 - 1.5e-71 241.5 0.1 2e-61 208.3 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EMR64073.1 - 8.9e-44 149.7 0.0 1.5e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Peptidase_M20 PF01546.28 EMR64074.1 - 9.4e-18 64.7 0.0 1.6e-17 63.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR64074.1 - 1.5e-09 37.7 0.1 3.7e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Uds1 PF15456.6 EMR64075.1 - 1.9e-19 70.1 5.7 1.1e-13 51.4 2.0 2.6 1 1 1 2 2 2 2 Up-regulated During Septation Stathmin PF00836.19 EMR64075.1 - 0.0058 16.6 1.5 0.038 13.9 1.5 2.3 1 1 0 1 1 1 1 Stathmin family PAP_central PF04928.17 EMR64075.1 - 0.15 11.0 0.1 0.28 10.1 0.1 1.4 1 1 0 1 1 1 0 Poly(A) polymerase central domain DUF1140 PF06600.11 EMR64075.1 - 0.18 12.3 0.4 0.33 11.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) FtsJ PF01728.19 EMR64076.1 - 1.5e-35 122.9 0.0 1.4e-34 119.7 0.0 1.9 1 1 1 2 2 2 2 FtsJ-like methyltransferase VCBS PF13517.6 EMR64077.1 - 0.35 11.5 6.4 11 6.7 0.3 4.8 4 2 3 7 7 7 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ABC_membrane PF00664.23 EMR64078.1 - 1.6e-63 214.9 29.2 1.8e-39 136.1 12.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMR64078.1 - 1e-61 207.4 0.0 2.6e-31 108.9 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMR64078.1 - 6.1e-16 58.5 0.1 0.00014 21.4 0.1 4.0 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMR64078.1 - 3.3e-09 37.4 0.3 0.003 18.0 0.0 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 EMR64078.1 - 2.6e-08 34.2 0.0 0.013 15.8 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMR64078.1 - 6e-08 32.3 0.3 0.00069 19.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMR64078.1 - 5.2e-07 29.7 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EMR64078.1 - 1.2e-06 29.0 0.5 1.6 9.1 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EMR64078.1 - 3.3e-06 26.9 0.2 0.17 11.6 0.0 3.6 3 1 0 3 3 3 2 AAA domain Rad17 PF03215.15 EMR64078.1 - 7.3e-06 26.0 0.0 0.01 15.8 0.0 2.7 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_7 PF12775.7 EMR64078.1 - 6.3e-05 22.6 0.0 0.14 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_ATPase PF09818.9 EMR64078.1 - 8.5e-05 21.5 0.1 0.11 11.3 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_18 PF13238.6 EMR64078.1 - 9.6e-05 22.9 0.0 0.8 10.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EMR64078.1 - 0.00015 21.8 0.2 1.7 8.6 0.0 3.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EMR64078.1 - 0.00016 21.5 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EMR64078.1 - 0.00021 21.2 0.0 1.8 8.3 0.0 3.1 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EMR64078.1 - 0.00057 20.1 2.4 1.4 9.2 0.2 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EMR64078.1 - 0.0008 19.6 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EMR64078.1 - 0.00095 18.9 0.2 1.9 8.2 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_23 PF13476.6 EMR64078.1 - 0.0012 19.4 0.3 1.5 9.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 EMR64078.1 - 0.0015 18.2 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EMR64078.1 - 0.0024 18.1 0.1 0.64 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EMR64078.1 - 0.004 16.8 1.3 1.4 8.5 0.0 2.9 3 1 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 EMR64078.1 - 0.0054 17.1 0.0 1.6 9.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase ATP_bind_1 PF03029.17 EMR64078.1 - 0.0056 16.5 0.1 0.66 9.7 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 EMR64078.1 - 0.0076 15.9 0.6 6.4 6.3 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 EMR64078.1 - 0.016 14.9 0.1 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Synapsin_N PF10581.9 EMR64078.1 - 0.017 15.1 0.0 0.65 10.0 0.0 2.4 2 0 0 2 2 2 0 Synapsin N-terminal TniB PF05621.11 EMR64078.1 - 0.041 13.3 0.1 17 4.7 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein Mg_chelatase PF01078.21 EMR64078.1 - 0.081 12.3 0.0 17 4.7 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 EMR64078.1 - 0.085 12.8 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase G-alpha PF00503.20 EMR64078.1 - 0.087 12.0 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit PRK PF00485.18 EMR64078.1 - 0.11 12.2 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EMR64078.1 - 0.13 11.4 0.1 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2057 PF09829.9 EMR64078.1 - 0.14 12.3 0.4 22 5.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) AAA_17 PF13207.6 EMR64078.1 - 0.36 11.3 1.6 38 4.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 EMR64079.1 - 1.1e-18 67.3 29.3 1.1e-18 67.3 29.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3708 PF12501.8 EMR64079.1 - 0.0048 16.7 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 Phosphate ATP-binding cassette transporter CENP-B_N PF04218.13 EMR64079.1 - 0.0096 15.5 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Amidase PF01425.21 EMR64080.1 - 1.4e-29 103.4 0.0 1e-24 87.3 0.0 2.6 2 1 0 2 2 2 2 Amidase Kinesin PF00225.23 EMR64081.1 - 1.2e-39 136.2 0.0 2.8e-39 135.0 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMR64081.1 - 1.2e-10 41.5 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 EMR64081.1 - 0.17 11.9 0.2 0.45 10.6 0.2 1.7 1 1 1 2 2 2 0 Helicase HerA, central domain Methyltransf_23 PF13489.6 EMR64082.1 - 3.1e-12 46.6 0.0 3.9e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR64082.1 - 6.8e-09 36.3 0.0 1.3e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR64082.1 - 2.5e-06 27.4 0.0 2.7e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR64082.1 - 0.0021 18.8 0.0 0.0079 16.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMR64082.1 - 0.0061 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 EMR64082.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EMR64082.1 - 0.018 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 EMR64082.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.14 EMR64082.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M48 PF01435.18 EMR64083.1 - 2.3e-34 118.9 0.0 4e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 HSP70 PF00012.20 EMR64084.1 - 1.8e-07 29.7 0.0 1.2e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMR64084.1 - 0.14 11.0 0.0 0.27 10.0 0.0 1.6 1 0 0 1 1 1 0 MreB/Mbl protein FAD_binding_4 PF01565.23 EMR64085.1 - 8.4e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Tet_JBP PF12851.7 EMR64086.1 - 0.0047 16.3 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DnaG_DnaB_bind PF08278.11 EMR64086.1 - 0.076 13.6 0.4 0.29 11.8 0.4 2.0 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding Mpv17_PMP22 PF04117.12 EMR64087.1 - 1.5e-08 34.7 1.8 5.9e-08 32.8 2.0 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family LPMO_10 PF03067.15 EMR64088.1 - 2.5e-12 47.9 0.0 3.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Myb_DNA-bind_6 PF13921.6 EMR64089.1 - 5.8e-09 36.1 0.1 9.1e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMR64089.1 - 0.00011 22.3 1.0 0.00014 22.0 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Vint PF14623.6 EMR64090.1 - 6.5e-64 214.7 0.0 1.2e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 EMR64090.1 - 3e-27 94.5 0.0 5e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 EMR64090.1 - 1.3e-13 51.5 0.0 3.1e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EMR64090.1 - 5.4e-12 45.9 0.0 7.7e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EMR64090.1 - 5.7e-12 46.2 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EMR64090.1 - 0.0071 15.8 0.0 0.026 13.9 0.0 1.8 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Hint PF01079.20 EMR64090.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Hint module CorA PF01544.18 EMR64091.1 - 0.15 11.3 2.4 5 6.4 0.1 2.4 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Methyltransf_25 PF13649.6 EMR64092.1 - 7.6e-13 49.0 0.0 1.3e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR64092.1 - 1.9e-11 44.5 0.0 3e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR64092.1 - 1.8e-09 38.2 0.0 2.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR64092.1 - 1.7e-08 34.5 0.0 2.5e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR64092.1 - 2.2e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EMR64092.1 - 0.00016 21.1 0.0 0.00023 20.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 EMR64092.1 - 0.00024 20.8 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EMR64092.1 - 0.00068 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EMR64092.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain NAD_synthase PF02540.17 EMR64093.1 - 3.9e-10 39.2 0.1 3.2e-06 26.4 0.1 2.1 2 0 0 2 2 2 2 NAD synthase GATase PF00117.28 EMR64093.1 - 5.9e-06 26.2 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I QueC PF06508.13 EMR64093.1 - 0.00014 21.4 0.0 0.00097 18.7 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 EMR64093.1 - 0.00027 20.7 0.1 0.00059 19.6 0.1 1.5 2 0 0 2 2 2 1 PP-loop family PAPS_reduct PF01507.19 EMR64093.1 - 0.0035 17.4 0.0 0.0051 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 EMR64093.1 - 0.0058 15.5 0.1 0.0099 14.7 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 EMR64093.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 EMR64093.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase SRF-TF PF00319.18 EMR64094.1 - 4.4e-21 74.1 0.1 6.2e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.14 EMR64094.1 - 0.2 9.9 0.5 0.25 9.6 0.5 1.1 1 0 0 1 1 1 0 CDC45-like protein MRI PF15325.6 EMR64094.1 - 2.6 9.2 5.0 0.72 11.0 0.5 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection eIF-1a PF01176.19 EMR64096.1 - 2.6e-22 78.4 0.0 3.8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.15 EMR64098.1 - 1.9e-18 67.1 0.0 3.7e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain DUF4780 PF16012.5 EMR64098.1 - 0.12 11.9 0.0 9.5 5.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4780) Tetraspanin PF00335.20 EMR64101.1 - 0.00098 18.9 6.3 0.0018 18.1 6.3 1.3 1 1 0 1 1 1 1 Tetraspanin family p450 PF00067.22 EMR64102.1 - 1.2e-34 119.8 0.0 1.4e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 fn3_2 PF16893.5 EMR64103.1 - 7.5e-38 128.6 0.0 1.3e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EMR64103.1 - 2.5e-23 81.8 0.7 4.2e-23 81.0 0.7 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EMR64103.1 - 1.7e-12 47.1 0.0 3.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EMR64103.1 - 6.9e-10 39.2 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 EMR64103.1 - 0.00015 21.9 0.0 0.0005 20.2 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 EMR64103.1 - 0.00056 20.3 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 EMR64103.1 - 0.0012 19.1 0.0 0.0035 17.7 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain CorA PF01544.18 EMR64104.1 - 0.0041 16.5 5.2 0.012 15.0 5.2 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TipE PF16972.5 EMR64104.1 - 0.33 10.1 2.1 0.28 10.3 0.8 1.4 1 1 0 1 1 1 0 Na+ channel auxiliary subunit TipE Vps16_N PF04841.13 EMR64106.1 - 2.9e-97 326.0 0.0 4.5e-97 325.4 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EMR64106.1 - 8.9e-79 264.8 0.0 1.3e-78 264.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EMR64106.1 - 0.008 16.5 0.0 0.23 11.8 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CdvA PF18822.1 EMR64107.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Surfac_D-trimer PF09006.11 EMR64107.1 - 0.071 13.0 0.8 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Flu_M2 PF00599.17 EMR64107.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M2) HET PF06985.11 EMR64108.1 - 2e-24 86.6 0.0 3.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fcf2 PF08698.11 EMR64109.1 - 6.8e-35 119.4 0.5 6.8e-35 119.4 0.5 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Pex14_N PF04695.13 EMR64109.1 - 0.062 14.0 2.5 0.095 13.4 2.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_1 PF00232.18 EMR64110.1 - 1.2e-147 492.1 0.0 1.4e-147 491.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sec15 PF04091.12 EMR64111.1 - 1.2e-93 314.0 1.2 1.2e-93 314.0 1.2 2.6 3 1 1 4 4 4 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.6 EMR64111.1 - 0.00014 21.7 3.6 0.00024 20.9 2.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF1704 PF08014.11 EMR64111.1 - 0.00095 18.3 0.6 0.17 10.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1704) DUF3510 PF12022.8 EMR64111.1 - 0.015 15.7 4.1 2.4 8.5 0.3 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF3510) DUF1192 PF06698.11 EMR64111.1 - 0.15 12.1 2.6 5.6 7.1 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SpoVIF PF14069.6 EMR64111.1 - 0.71 9.7 3.6 28 4.6 0.1 4.2 5 1 0 5 5 5 0 Stage VI sporulation protein F Spc29 PF17082.5 EMR64111.1 - 0.89 9.3 6.8 1.3 8.8 1.7 3.0 3 0 0 3 3 3 0 Spindle Pole Component 29 Sec8_exocyst PF04048.14 EMR64111.1 - 2.2 8.1 8.3 0.92 9.4 2.6 2.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Hrs_helical PF12210.8 EMR64111.1 - 8.6 7.0 12.5 3.2 8.4 3.1 3.9 4 0 0 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate tRNA_synthFbeta PF17759.1 EMR64112.1 - 8.8e-46 156.0 0.0 1.4e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EMR64112.1 - 5e-33 113.2 0.9 5.1e-32 109.9 0.3 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EMR64112.1 - 7.1e-25 87.7 0.0 1.3e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EMR64112.1 - 4.3e-16 59.0 0.0 2.5e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain WD40 PF00400.32 EMR64113.1 - 2.6e-14 53.4 12.3 0.0049 17.7 0.6 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR64113.1 - 9.9e-07 29.0 0.0 0.91 9.9 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MraZ PF02381.18 EMR64113.1 - 0.11 12.5 0.0 23 5.1 0.0 2.5 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like PHTB1_N PF14727.6 EMR64113.1 - 0.17 11.2 0.0 7 5.9 0.0 2.3 1 1 1 2 2 2 0 PTHB1 N-terminus Cwf_Cwc_15 PF04889.12 EMR64113.1 - 0.25 11.1 6.2 0.61 9.8 6.2 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tub_N PF16322.5 EMR64113.1 - 1.6 9.1 8.5 0.83 10.0 3.5 2.3 2 0 0 2 2 2 0 Tubby N-terminal Fructosamin_kin PF03881.14 EMR64114.1 - 3.9e-25 88.6 0.0 5.2e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EMR64114.1 - 7.4e-13 49.0 0.0 1.1e-12 48.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EMR64114.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 EMR64114.1 - 0.033 13.8 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SNF2_N PF00176.23 EMR64115.1 - 4.9e-74 249.1 0.8 1.5e-73 247.6 0.8 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR64115.1 - 4.6e-22 78.5 0.3 3.8e-18 65.8 0.0 4.2 4 0 0 4 4 4 2 Helicase conserved C-terminal domain Bromodomain PF00439.25 EMR64115.1 - 1.3e-21 76.4 0.1 3.1e-20 72.0 0.1 2.6 2 0 0 2 2 2 1 Bromodomain HSA PF07529.13 EMR64115.1 - 2.4e-18 66.2 13.3 2.4e-18 66.2 13.3 6.1 7 1 0 7 7 7 1 HSA SnAC PF14619.6 EMR64115.1 - 1.3e-12 48.1 0.2 1.3e-12 48.1 0.2 3.7 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 EMR64115.1 - 1.4e-10 41.5 0.0 1.4e-10 41.5 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit QLQ PF08880.11 EMR64115.1 - 1.7e-10 40.5 8.5 1.7e-10 40.5 8.5 3.1 3 0 0 3 3 3 1 QLQ RBR PF17208.3 EMR64115.1 - 0.0073 17.0 4.7 0.0073 17.0 4.7 3.5 4 1 1 5 5 5 1 RNA binding Region Sad1_UNC PF07738.13 EMR64116.1 - 5.3e-31 107.4 0.0 1e-30 106.5 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ANAPC4_WD40 PF12894.7 EMR64116.1 - 5.9e-10 39.3 0.0 0.033 14.5 0.0 5.6 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMR64116.1 - 0.012 16.4 0.0 50 5.0 0.0 5.1 5 0 0 5 5 5 0 WD domain, G-beta repeat CBFD_NFYB_HMF PF00808.23 EMR64117.1 - 2.5e-19 69.3 0.5 3.6e-19 68.8 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMR64117.1 - 5.3e-15 55.9 0.2 8.8e-15 55.2 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EMR64117.1 - 0.047 14.0 0.1 0.074 13.4 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X BDM PF10684.9 EMR64117.1 - 0.25 11.7 0.8 0.52 10.7 0.2 1.8 2 0 0 2 2 2 0 Putative biofilm-dependent modulation protein RRM_2 PF04059.12 EMR64118.1 - 2.4e-32 111.0 0.2 3.7e-32 110.4 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EMR64118.1 - 0.0083 15.9 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EMR64119.1 - 1.4e-10 40.8 0.0 1.4e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAF4 PF05236.14 EMR64119.1 - 5.4 6.7 22.1 11 5.7 22.1 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family HEAT PF02985.22 EMR64120.1 - 2e-38 127.1 17.4 0.015 15.5 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 EMR64120.1 - 9.5e-34 115.7 4.9 8.8e-10 38.9 0.0 8.1 4 2 5 9 9 9 9 HEAT repeats Cnd1 PF12717.7 EMR64120.1 - 2.7e-10 40.5 11.7 0.011 15.8 0.1 5.9 4 2 1 6 6 6 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EMR64120.1 - 3.4e-10 40.4 3.2 0.012 16.2 0.1 7.5 5 2 4 9 9 9 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EMR64120.1 - 6.2e-10 39.4 8.4 0.033 14.7 0.0 8.5 8 2 2 10 10 9 2 HEAT-like repeat Adaptin_N PF01602.20 EMR64120.1 - 1.5e-07 30.3 9.5 0.096 11.2 0.2 5.3 3 2 2 6 6 6 3 Adaptin N terminal region RTP1_C1 PF10363.9 EMR64120.1 - 5.8e-06 26.5 5.4 1.2 9.3 0.0 5.2 3 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EMR64120.1 - 8.5e-05 22.2 1.0 2 8.0 0.2 4.6 3 2 1 5 5 5 2 CLASP N terminal Proteasom_PSMB PF10508.9 EMR64120.1 - 0.014 14.0 3.6 0.34 9.4 0.1 2.4 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF3895 PF13034.6 EMR64120.1 - 0.039 14.0 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Arm PF00514.23 EMR64120.1 - 0.078 13.1 4.9 3.1 8.0 0.0 4.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat M11L PF11099.8 EMR64120.1 - 0.15 12.4 0.1 33 4.7 0.0 3.1 2 1 1 3 3 3 0 Apoptosis regulator M11L like Ecm29 PF13001.7 EMR64120.1 - 0.18 10.4 4.1 10 4.6 0.0 4.0 4 1 0 5 5 5 0 Proteasome stabiliser IFRD PF05004.13 EMR64120.1 - 0.31 10.1 1.0 4.2 6.4 0.0 2.9 3 2 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Mg_trans_NIPA PF05653.14 EMR64121.1 - 1.6e-36 125.9 1.9 2.7e-33 115.4 0.3 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EMR64121.1 - 0.00042 20.5 2.4 0.00042 20.5 2.4 3.0 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 EMR64121.1 - 0.012 15.1 0.4 0.018 14.6 0.4 1.3 1 0 0 1 1 1 0 Solute carrier family 35 DUF5362 PF17319.2 EMR64121.1 - 0.067 13.0 2.7 0.18 11.6 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5362) VMA21 PF09446.10 EMR64121.1 - 2.1 8.5 7.6 0.13 12.4 1.8 1.9 2 0 0 2 2 2 0 VMA21-like domain Myotub-related PF06602.14 EMR64123.1 - 2e-104 349.3 0.0 2.7e-104 348.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EMR64123.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family Methyltransf_31 PF13847.6 EMR64124.1 - 6.4e-11 42.3 0.0 3.9e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EMR64124.1 - 0.00021 22.0 0.3 0.00055 20.6 0.3 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR64124.1 - 0.00067 20.3 0.1 0.0024 18.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EMR64124.1 - 0.0031 17.5 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR64124.1 - 0.019 15.6 0.1 0.062 14.0 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain ADH_N PF08240.12 EMR64126.1 - 1.2e-27 96.0 0.1 3.7e-27 94.3 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR64126.1 - 3.2e-22 78.9 0.5 4.6e-22 78.4 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR64126.1 - 6.3e-07 30.5 0.0 1e-06 29.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR64126.1 - 0.14 11.6 1.7 0.21 11.0 1.2 1.5 1 1 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.16 EMR64127.1 - 2.2e-12 46.6 62.7 1.9e-11 43.5 58.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyoxalase PF00903.25 EMR64128.1 - 0.00011 22.4 0.7 0.0017 18.6 0.5 2.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMR64128.1 - 0.013 15.7 0.1 0.15 12.3 0.1 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pyr_redox_2 PF07992.14 EMR64131.1 - 1.9e-11 43.8 0.1 1.9e-08 33.9 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR64131.1 - 0.0011 18.0 0.8 0.0031 16.4 0.3 2.0 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 EMR64131.1 - 0.0015 18.2 1.5 0.0089 15.7 0.6 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR64131.1 - 0.0021 18.1 0.0 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EMR64131.1 - 0.02 14.0 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMR64131.1 - 0.023 14.9 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EMR64131.1 - 0.045 13.0 0.1 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EMR64131.1 - 0.11 11.8 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EMR64131.1 - 0.17 12.4 0.1 0.42 11.2 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IN_DBD_C PF00552.21 EMR64131.1 - 1.4 8.3 4.1 1.2 8.5 1.2 2.3 2 0 0 2 2 2 0 Integrase DNA binding domain PTR2 PF00854.21 EMR64132.1 - 1.3e-20 73.7 0.6 1.8e-20 73.1 0.6 1.3 1 0 0 1 1 1 1 POT family DELLA PF12041.8 EMR64132.1 - 0.19 11.6 0.1 1.5 8.7 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal FAD_binding_3 PF01494.19 EMR64133.1 - 3.5e-42 144.9 0.0 3.1e-41 141.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR64133.1 - 2.6e-05 23.6 0.8 4.4e-05 22.9 0.4 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR64133.1 - 0.00051 19.3 0.1 0.00093 18.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EMR64133.1 - 0.0016 17.6 0.3 0.0024 17.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR64133.1 - 0.0059 16.8 0.1 0.015 15.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR64133.1 - 0.01 15.1 0.2 0.018 14.3 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR64133.1 - 0.031 13.3 0.1 0.19 10.7 0.3 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 EMR64133.1 - 0.031 13.0 0.1 0.046 12.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 EMR64133.1 - 0.14 11.7 0.2 0.3 10.6 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_PK PF05891.12 EMR64134.1 - 1.1e-81 273.5 0.0 1.2e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 EMR64134.1 - 3.5e-05 24.4 0.0 5.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR64134.1 - 8.4e-05 23.2 0.0 0.00016 22.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR64134.1 - 0.00048 20.0 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR64134.1 - 0.0011 19.7 0.0 0.0017 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RNA_pol_Rpa2_4 PF06883.12 EMR64134.1 - 0.081 13.0 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain CMAS PF02353.20 EMR64134.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 EMR64134.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain RSN1_7TM PF02714.15 EMR64135.1 - 2.5e-74 250.0 20.9 3.4e-74 249.6 20.9 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EMR64135.1 - 2.4e-40 138.6 0.0 3.5e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EMR64135.1 - 0.00064 18.7 0.5 0.00064 18.7 0.5 1.9 2 0 0 2 2 2 1 Calcium-activated chloride channel Glyco_transf_20 PF00982.21 EMR64136.1 - 6e-161 536.3 0.1 8.5e-161 535.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EMR64136.1 - 1.3e-42 145.6 0.0 2.2e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 EMR64136.1 - 0.1 12.3 0.4 0.22 11.2 0.4 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF3761 PF12587.8 EMR64136.1 - 0.13 12.7 3.1 2 8.9 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3761) DUF4873 PF16170.5 EMR64136.1 - 0.17 12.1 0.2 0.95 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4873) Lactonase PF10282.9 EMR64137.1 - 2.5e-17 63.2 0.0 7.6e-17 61.6 0.0 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 EMR64137.1 - 0.048 12.7 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) HalOD2 PF18547.1 EMR64137.1 - 0.13 12.2 0.5 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Halobacterial output domain 2 Sugar_tr PF00083.24 EMR64138.1 - 5.7e-95 318.8 24.0 6.7e-95 318.6 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR64138.1 - 3.2e-20 72.3 38.1 9e-20 70.9 28.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR64138.1 - 0.0001 20.9 1.5 0.00022 19.8 1.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5527 PF17665.1 EMR64138.1 - 0.14 11.7 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) MFS_1 PF07690.16 EMR64139.1 - 1.8e-33 116.0 21.3 2.2e-33 115.7 21.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR64139.1 - 1.7e-11 43.7 15.5 4.2e-11 42.4 15.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter PIF1 PF05970.14 EMR64140.1 - 1.5e-29 103.4 0.0 2.2e-17 63.3 0.0 2.6 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EMR64140.1 - 1.9e-13 50.5 0.0 2.2e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain Herpes_Helicase PF02689.14 EMR64140.1 - 5.1e-06 24.7 0.0 7.8e-06 24.1 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.6 EMR64140.1 - 1.2e-05 25.6 0.0 0.00018 21.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 EMR64140.1 - 5.8e-05 22.8 0.1 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EMR64140.1 - 0.0092 15.7 0.0 0.092 12.5 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase OrfB_Zn_ribbon PF07282.11 EMR64140.1 - 0.04 13.9 0.2 0.083 12.8 0.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain CobA_CobO_BtuR PF02572.15 EMR64140.1 - 0.15 12.3 0.1 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Inhibitor_I9 PF05922.16 EMR64141.1 - 4e-11 43.4 0.5 6.7e-11 42.7 0.5 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 EMR64141.1 - 1e-10 41.4 7.2 3.8e-07 29.7 1.0 2.2 1 1 1 2 2 2 2 Subtilase family EcKinase PF02958.20 EMR64142.1 - 7.6e-10 38.6 0.0 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 EMR64142.1 - 3.4e-07 30.4 1.8 4.1e-07 30.2 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMR64142.1 - 0.07 12.7 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase AA_permease_2 PF13520.6 EMR64143.1 - 3.9e-90 302.7 35.0 3.9e-90 302.7 35.0 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR64143.1 - 5.1e-20 71.5 29.6 9.3e-20 70.7 29.6 1.4 1 1 0 1 1 1 1 Amino acid permease DUF3112 PF11309.8 EMR64143.1 - 0.21 11.0 2.9 0.14 11.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) TctB PF07331.11 EMR64143.1 - 1.3 9.3 31.9 0.38 11.0 1.1 4.3 3 2 1 4 4 4 0 Tripartite tricarboxylate transporter TctB family adh_short PF00106.25 EMR64145.1 - 1.2e-40 139.0 0.5 1.7e-40 138.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64145.1 - 1.4e-29 103.4 0.3 1.9e-29 102.9 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EMR64145.1 - 5.5e-07 29.3 0.0 1.7e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EMR64145.1 - 5.8e-07 29.6 0.3 9.2e-07 28.9 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR64145.1 - 0.0004 20.3 1.3 0.0012 18.7 1.3 1.9 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMR64145.1 - 0.0016 18.0 1.2 0.002 17.7 0.6 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR64145.1 - 0.014 14.9 0.3 0.099 12.1 0.7 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Aminotran_4 PF01063.19 EMR64146.1 - 1.1e-22 81.0 0.0 1.3e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_hydro_43 PF04616.14 EMR64147.1 - 9.2e-50 169.6 7.1 9.2e-50 169.6 7.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Laminin_G_1 PF00054.23 EMR64147.1 - 0.00082 19.6 0.2 0.0026 18.0 0.1 1.9 3 0 0 3 3 3 1 Laminin G domain CBM_4_9 PF02018.17 EMR64147.1 - 0.013 15.7 1.3 4.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Carbohydrate binding domain Ifi-6-16 PF06140.13 EMR64147.1 - 0.021 14.7 0.5 0.021 14.7 0.5 2.5 3 0 0 3 3 3 0 Interferon-induced 6-16 family Laminin_G_2 PF02210.24 EMR64147.1 - 0.09 13.4 0.1 0.63 10.6 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain MutS_V PF00488.21 EMR64148.1 - 3.1e-17 63.2 0.1 4.3e-11 43.2 0.2 2.3 1 1 1 2 2 2 2 MutS domain V MutS_V PF00488.21 EMR64149.1 - 7.9e-66 221.7 0.3 3.7e-64 216.2 0.1 2.6 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EMR64149.1 - 1.8e-35 122.9 3.3 1.8e-35 122.9 3.3 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EMR64149.1 - 3.8e-29 101.2 0.0 8.6e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EMR64149.1 - 1.1e-09 38.6 0.4 9.6e-09 35.6 0.1 2.7 2 1 1 3 3 3 1 MutS domain II MutS_IV PF05190.18 EMR64149.1 - 0.00039 20.7 0.0 0.0014 18.9 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 EMR64149.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) AAA_27 PF13514.6 EMR64149.1 - 0.046 13.3 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 EMR64151.1 - 1.1e-12 47.6 18.3 1.6e-12 47.1 18.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HPP PF04982.13 EMR64152.1 - 3.2e-40 137.1 6.6 4.2e-40 136.7 6.6 1.1 1 0 0 1 1 1 1 HPP family FAD_binding_4 PF01565.23 EMR64153.1 - 2.6e-13 49.9 0.2 5.6e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 EMR64153.1 - 6.2e-11 42.4 0.0 9.3e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMR64154.1 - 1.9e-17 63.3 1.1 4e-17 62.2 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR64154.1 - 1.9e-10 40.7 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like EF-hand_7 PF13499.6 EMR64155.1 - 1.2e-11 44.9 0.2 6e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EMR64155.1 - 1.9e-11 44.1 0.0 3.7e-05 24.0 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EMR64155.1 - 1e-08 34.4 1.0 0.0055 16.5 0.0 3.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EMR64155.1 - 4.2e-08 32.2 0.3 0.021 14.4 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EMR64155.1 - 4.5e-07 29.6 0.2 0.00041 20.2 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair FMO-like PF00743.19 EMR64157.1 - 1e-16 60.5 0.0 7.2e-16 57.7 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR64157.1 - 5.8e-16 58.6 0.0 1.2e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR64157.1 - 4.9e-12 45.7 0.0 8.9e-11 41.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR64157.1 - 1.5e-09 37.5 0.1 2.7e-06 26.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EMR64157.1 - 1e-05 25.7 0.6 9.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR64157.1 - 0.0005 19.8 2.8 0.0023 17.6 2.3 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR64157.1 - 0.00057 20.4 4.2 0.13 12.9 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EMR64157.1 - 0.0011 19.1 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EMR64157.1 - 0.0017 17.7 0.4 0.19 11.0 0.2 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EMR64157.1 - 0.012 15.7 1.0 0.27 11.2 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EMR64157.1 - 0.02 14.8 1.7 0.037 13.9 1.4 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EMR64157.1 - 0.038 13.1 2.5 0.13 11.4 0.9 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EMR64157.1 - 0.053 12.2 1.5 0.72 8.5 0.3 2.5 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 EMR64157.1 - 0.14 11.2 1.6 2.6 7.0 0.5 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A p450 PF00067.22 EMR64158.1 - 9.1e-26 90.6 0.6 1.3e-17 63.7 0.8 2.0 1 1 1 2 2 2 2 Cytochrome P450 DHO_dh PF01180.21 EMR64159.1 - 1.8e-61 207.9 0.0 1.7e-50 171.9 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase ApoL PF05461.11 EMR64159.1 - 0.0073 15.7 2.2 0.19 11.0 0.0 2.2 1 1 1 2 2 2 2 Apolipoprotein L QCR10 PF09796.9 EMR64160.1 - 3.8e-26 90.9 0.2 5.1e-26 90.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Peptidase_M3 PF01432.20 EMR64161.1 - 1e-122 410.7 0.0 1.5e-122 410.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EMR64161.1 - 0.0053 17.1 0.9 0.2 11.9 0.0 2.5 3 0 0 3 3 3 1 Effector protein DPBB_1 PF03330.18 EMR64162.1 - 0.00014 22.0 0.0 0.00017 21.8 0.0 1.3 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EMR64162.1 - 0.00093 19.0 0.3 0.0012 18.6 0.3 1.3 1 0 0 1 1 1 1 Barwin family Aminotran_3 PF00202.21 EMR64163.1 - 1.7e-51 175.2 2.0 3.1e-38 131.5 0.5 2.1 2 0 0 2 2 2 2 Aminotransferase class-III DIOX_N PF14226.6 EMR64164.1 - 3.7e-29 101.9 0.1 6.6e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR64164.1 - 1.2e-16 61.0 0.0 5.6e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Polysacc_deac_1 PF01522.21 EMR64165.1 - 4.1e-25 88.1 0.1 6.1e-25 87.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMR64165.1 - 0.0075 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF1996 PF09362.10 EMR64166.1 - 3.5e-65 220.3 6.2 6.1e-35 121.3 3.7 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) EMP70 PF02990.16 EMR64167.1 - 8.3e-209 694.6 4.9 1.2e-208 694.0 4.9 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Transp_cyt_pur PF02133.15 EMR64168.1 - 1.5e-60 205.2 21.0 1.7e-60 205.0 21.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Med4 PF10018.9 EMR64169.1 - 9.9e-38 129.8 0.0 1.6e-37 129.1 0.0 1.3 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 SART-1 PF03343.13 EMR64169.1 - 0.00046 18.9 3.6 0.00067 18.4 3.6 1.2 1 0 0 1 1 1 1 SART-1 family Neuropep_like PF15161.6 EMR64169.1 - 0.025 14.2 0.5 0.35 10.6 0.4 2.3 2 0 0 2 2 2 0 Neuropeptide-like SOG2 PF10428.9 EMR64169.1 - 0.12 11.6 6.2 0.55 9.4 5.7 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein Sporozoite_P67 PF05642.11 EMR64169.1 - 0.14 10.2 16.7 2.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Presenilin PF01080.17 EMR64169.1 - 0.8 8.4 1.4 1.1 8.0 1.4 1.2 1 0 0 1 1 1 0 Presenilin M_domain PF12938.7 EMR64169.1 - 2 8.2 10.1 4.6 7.0 10.1 1.5 1 0 0 1 1 1 0 M domain of GW182 DDRGK PF09756.9 EMR64169.1 - 7.3 6.1 17.7 11 5.6 17.7 1.2 1 0 0 1 1 1 0 DDRGK domain DIE2_ALG10 PF04922.12 EMR64170.1 - 8.4e-78 262.4 7.0 4.2e-55 187.6 1.9 2.1 2 0 0 2 2 2 2 DIE2/ALG10 family BaxI_1 PF12811.7 EMR64170.1 - 0.011 15.3 0.9 0.023 14.3 0.2 1.9 2 0 0 2 2 2 0 Bax inhibitor 1 like Mg_trans_NIPA PF05653.14 EMR64171.1 - 2e-86 289.7 26.8 2.8e-86 289.3 26.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EMR64171.1 - 1.5e-05 25.2 7.3 1.5e-05 25.2 7.3 3.1 3 0 0 3 3 3 1 EamA-like transporter family SprA-related PF12118.8 EMR64171.1 - 1.2 8.2 8.5 0.32 10.1 3.1 2.1 2 0 0 2 2 2 0 SprA-related family TFIIA PF03153.13 EMR64171.1 - 3.5 7.5 19.3 6.6 6.6 19.3 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sas10_Utp3 PF04000.15 EMR64172.1 - 4.9e-18 65.5 2.3 4.9e-18 65.5 2.3 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF4611 PF15387.6 EMR64172.1 - 0.053 13.8 4.7 7.7 6.8 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RNA12 PF10443.9 EMR64173.1 - 1.3e-161 538.3 0.3 1.6e-161 538.0 0.3 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 EMR64173.1 - 1.5e-05 24.8 0.0 0.00014 21.6 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 EMR64173.1 - 3.9e-05 23.7 0.2 0.00066 19.7 0.2 2.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 EMR64173.1 - 0.0037 17.3 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) adh_short PF00106.25 EMR64174.1 - 1.8e-35 122.2 0.0 4.6e-35 120.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64174.1 - 5.4e-27 94.8 0.0 2.4e-25 89.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64174.1 - 0.00099 19.1 0.1 0.0019 18.1 0.1 1.5 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EMR64174.1 - 0.045 13.7 0.2 0.086 12.8 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 EMR64174.1 - 0.058 12.8 0.2 0.2 11.1 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EMR64174.1 - 0.06 12.7 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain BNR PF02012.20 EMR64176.1 - 0.098 12.7 0.5 0.34 11.1 0.5 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat Mo25 PF08569.11 EMR64177.1 - 1.3e-129 432.3 0.0 1.5e-129 432.1 0.0 1.0 1 0 0 1 1 1 1 Mo25-like GFA PF04828.14 EMR64178.1 - 5e-15 55.6 0.0 7.1e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Mito_carr PF00153.27 EMR64180.1 - 1.1e-30 105.4 0.2 9.5e-16 57.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SWIB PF02201.18 EMR64181.1 - 6.6e-22 77.2 0.0 1.3e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain TFIIA PF03153.13 EMR64181.1 - 0.31 11.0 6.1 0.57 10.1 6.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.6 EMR64181.1 - 2.6 8.5 12.5 0.11 12.9 4.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OPT PF03169.15 EMR64182.1 - 2.7e-137 459.0 19.0 3.2e-137 458.8 19.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 EMR64182.1 - 0.068 13.2 0.9 1 9.4 0.2 3.2 3 0 0 3 3 3 0 Bacteriophage P21 holin S Gly-zipper_YMGG PF13441.6 EMR64182.1 - 6.3 6.6 8.2 15 5.4 3.1 3.2 3 0 0 3 3 3 0 YMGG-like Gly-zipper RGS PF00615.19 EMR64183.1 - 3.9e-05 23.9 0.0 0.00018 21.7 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain Tannase PF07519.11 EMR64184.1 - 3.2e-89 300.0 0.7 6.7e-89 298.9 0.7 1.5 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EMR64184.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3128 PF11326.8 EMR64186.1 - 2.5e-26 91.8 4.1 3.9e-26 91.2 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) tRNA-synt_1 PF00133.22 EMR64187.1 - 3.1e-216 719.3 0.5 3.1e-216 719.3 0.5 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMR64187.1 - 5.1e-25 88.2 0.0 2.8e-24 85.8 0.0 2.2 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMR64187.1 - 3.3e-16 59.0 0.2 2.4e-06 26.6 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EMR64187.1 - 0.0068 15.8 0.0 0.062 12.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain ANAPC_CDC26 PF10471.9 EMR64188.1 - 0.0045 17.8 0.0 0.0045 17.8 0.0 3.9 3 2 1 4 4 4 1 Anaphase-promoting complex APC subunit CDC26 DUF1962 PF09227.10 EMR64189.1 - 4.5e-05 23.7 11.2 5.4e-05 23.5 10.3 1.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1962) Pkinase PF00069.25 EMR64190.1 - 2.1e-68 230.6 0.0 2.6e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64190.1 - 8.4e-35 120.3 0.0 8.5e-34 117.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR64190.1 - 5.1e-06 26.0 0.1 0.015 14.6 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 EMR64190.1 - 2e-05 23.7 0.0 2.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMR64190.1 - 0.00037 19.9 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR64190.1 - 0.0027 17.7 0.1 0.01 15.8 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EMR64190.1 - 0.0028 17.3 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EMR64190.1 - 0.094 12.3 0.0 0.26 10.9 0.0 1.8 1 1 0 1 1 1 0 RIO1 family Sugar_tr PF00083.24 EMR64191.1 - 1.7e-88 297.5 32.6 2e-88 297.3 32.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR64191.1 - 7.6e-27 94.1 38.7 7.6e-27 94.1 38.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR64191.1 - 0.0013 17.2 15.5 0.0024 16.4 15.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TM140 PF14985.6 EMR64191.1 - 0.028 14.0 6.0 0.42 10.1 4.2 2.5 2 0 0 2 2 2 0 TM140 protein family Sacchrp_dh_NADP PF03435.18 EMR64192.1 - 4.8e-15 56.0 0.0 1e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EMR64192.1 - 1e-06 28.7 0.0 2.4e-06 27.6 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding GCV_H PF01597.19 EMR64192.1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Glycine cleavage H-protein RNA_pol_Rpc82 PF05645.13 EMR64193.1 - 1.1e-55 189.2 0.0 4.5e-54 183.9 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EMR64193.1 - 0.0098 16.0 3.4 0.068 13.3 0.3 3.6 4 1 1 5 5 5 2 RNA polymerase III subunit RPC82 helix-turn-helix domain Rav1p_C PF12234.8 EMR64194.1 - 7.1e-260 863.9 0.0 2.6e-245 815.7 0.0 2.1 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 EMR64194.1 - 0.039 14.8 0.4 0.4 11.6 0.0 3.1 4 0 0 4 4 4 0 WD domain, G-beta repeat adh_short_C2 PF13561.6 EMR64195.1 - 2.9e-55 187.4 6.2 4.6e-55 186.7 6.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR64195.1 - 1.1e-42 145.7 6.0 1.6e-42 145.2 6.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR64195.1 - 4.8e-15 55.9 3.9 1.1e-14 54.8 3.9 1.5 1 0 0 1 1 1 1 KR domain Ribonucleas_3_3 PF14622.6 EMR64195.1 - 2.4e-05 24.5 0.0 5.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Epimerase PF01370.21 EMR64195.1 - 0.00055 19.5 1.8 0.0018 17.8 1.8 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AIRC PF00731.20 EMR64195.1 - 0.042 13.4 0.3 0.042 13.4 0.3 2.0 2 0 0 2 2 2 0 AIR carboxylase Glyco_tranf_2_3 PF13641.6 EMR64195.1 - 0.046 13.6 0.3 0.092 12.6 0.3 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 F420_oxidored PF03807.17 EMR64195.1 - 0.054 14.1 0.7 0.24 12.0 0.7 2.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyridoxal_deC PF00282.19 EMR64195.1 - 0.07 11.8 0.7 0.095 11.4 0.1 1.5 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain YAcAr PF10686.9 EMR64195.1 - 0.21 11.5 2.0 0.93 9.5 1.1 2.5 2 1 0 2 2 2 0 YspA, cpYpsA-related SLOG family HSP70 PF00012.20 EMR64196.1 - 6.3e-259 860.2 5.1 7.2e-259 860.0 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMR64196.1 - 2.9e-16 59.2 0.0 3.8e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EMR64196.1 - 0.0024 18.3 1.8 4.6 7.7 0.2 3.4 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 EMR64196.1 - 0.0052 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EMR64196.1 - 0.017 14.4 0.1 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EMR64196.1 - 0.037 13.5 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 EMR64196.1 - 0.043 13.0 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein PMBR PF09373.10 EMR64196.1 - 0.35 11.1 1.3 0.51 10.6 0.1 2.0 2 0 0 2 2 2 0 Pseudomurein-binding repeat Sfi1 PF08457.10 EMR64197.1 - 9.2e-34 116.9 85.8 1.1e-23 83.6 25.8 6.7 3 2 2 6 6 6 5 Sfi1 spindle body protein ADH_zinc_N_2 PF13602.6 EMR64198.1 - 1.9e-11 45.1 0.0 4.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR64198.1 - 2.8e-11 43.5 0.1 6.8e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR64198.1 - 3.6e-08 33.3 0.0 1.4e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Dynamin_N PF00350.23 EMR64199.1 - 6.8e-31 107.6 1.8 7.9e-31 107.4 0.0 2.0 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 EMR64199.1 - 6.7e-06 26.2 0.8 6.7e-06 26.2 0.8 2.6 3 1 0 3 3 3 1 Dynamin GTPase effector domain AAA_15 PF13175.6 EMR64199.1 - 0.00015 21.7 0.0 0.00031 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EMR64199.1 - 0.00047 20.2 0.0 0.0021 18.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 EMR64199.1 - 0.00049 19.4 0.0 0.0017 17.6 0.1 1.9 1 1 0 1 1 1 1 Dynamin central region ABC_tran PF00005.27 EMR64199.1 - 0.0067 16.9 0.0 0.078 13.5 0.0 2.4 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EMR64199.1 - 0.0081 16.0 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMR64199.1 - 0.0094 16.5 1.4 1.1 9.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMR64199.1 - 0.021 14.5 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5388 PF17363.2 EMR64199.1 - 0.089 13.0 0.1 0.3 11.3 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5388) PilJ PF13675.6 EMR64199.1 - 0.13 12.3 4.5 0.78 9.8 0.4 2.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_16 PF13191.6 EMR64199.1 - 0.14 12.6 1.2 1 9.8 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain LMBR1 PF04791.16 EMR64199.1 - 0.15 10.9 0.2 0.24 10.3 0.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MapZ_EC1 PF18041.1 EMR64199.1 - 0.55 10.5 4.3 4.2 7.6 0.4 2.5 2 0 0 2 2 2 0 MapZ extracellular domain 1 GEN1_C PF18380.1 EMR64200.1 - 2.5e-29 102.3 0.1 1.6e-27 96.4 0.0 2.6 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 EMR64200.1 - 3.5e-26 91.4 0.0 1e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EMR64200.1 - 2.4e-08 34.4 0.0 6.2e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Endonuc-MspI PF09208.10 EMR64200.1 - 0.076 12.4 0.3 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 Restriction endonuclease MspI Actin PF00022.19 EMR64202.1 - 1.5e-07 30.4 0.0 0.0062 15.2 0.0 2.4 2 0 0 2 2 2 2 Actin SOG2 PF10428.9 EMR64202.1 - 0.36 10.0 5.3 0.66 9.1 5.3 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Fe_dep_repress PF01325.19 EMR64203.1 - 0.048 13.9 0.2 0.35 11.1 0.2 2.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Vps4_C PF09336.10 EMR64203.1 - 0.13 12.3 0.3 6.9 6.8 0.1 3.8 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain DNA_meth_N PF18284.1 EMR64203.1 - 0.22 11.4 1.7 2 8.4 0.2 3.5 2 1 0 2 2 2 0 DNA methylase N-terminal domain DNTTIP1_dimer PF18192.1 EMR64203.1 - 0.26 11.7 4.3 7.7 6.9 0.1 4.5 4 0 0 4 4 4 0 DNTTIP1 dimerisation domain TFIID-31kDa PF02291.15 EMR64203.1 - 0.52 10.4 3.7 11 6.1 0.0 3.4 3 0 0 3 3 3 0 Transcription initiation factor IID, 31kD subunit DUF2795 PF11387.8 EMR64203.1 - 4.8 7.5 22.6 48 4.3 0.1 7.7 4 1 4 8 8 8 0 Protein of unknown function (DUF2795) adh_short PF00106.25 EMR64205.1 - 3.5e-34 118.0 1.1 5.6e-34 117.3 1.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64205.1 - 7.6e-31 107.5 0.2 2.2e-30 106.0 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64205.1 - 1.4e-06 28.3 2.7 1.4e-06 28.3 2.7 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 EMR64205.1 - 0.0024 17.8 2.0 0.017 15.0 2.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox PF00070.27 EMR64205.1 - 0.0052 17.3 0.7 0.045 14.3 1.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMR64205.1 - 0.015 15.6 0.5 0.025 14.8 0.5 1.3 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 EMR64205.1 - 0.028 13.9 2.9 0.031 13.7 0.5 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR64205.1 - 0.037 13.0 0.1 0.054 12.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 EMR64205.1 - 0.04 13.8 2.5 0.056 13.3 2.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMR64205.1 - 0.05 13.9 0.8 0.076 13.3 0.8 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 EMR64205.1 - 0.11 12.5 1.5 0.18 11.8 1.5 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RRM_1 PF00076.22 EMR64206.1 - 2.8e-08 33.4 0.0 2.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLH PF01738.18 EMR64207.1 - 7.3e-18 64.9 0.0 1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EMR64207.1 - 0.002 18.1 0.0 0.0082 16.1 0.0 1.7 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EMR64207.1 - 0.055 13.1 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) HGTP_anticodon PF03129.20 EMR64208.1 - 1.4e-20 73.2 0.1 1.4e-20 73.2 0.1 3.1 3 1 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EMR64208.1 - 2.7e-09 37.2 0.0 6.9e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Bystin PF05291.11 EMR64208.1 - 0.35 10.1 1.5 0.64 9.3 1.5 1.3 1 0 0 1 1 1 0 Bystin tRNA-synt_2b PF00587.25 EMR64209.1 - 2.3e-18 66.8 0.0 3.6e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EMR64209.1 - 1.2e-11 44.8 3.9 2.4e-05 24.5 3.2 2.3 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DUF737 PF05300.11 EMR64209.1 - 0.096 13.0 3.5 0.18 12.2 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Ribosomal_L29 PF00831.23 EMR64209.1 - 0.67 10.0 7.0 0.2 11.6 3.4 2.0 2 0 0 2 2 2 0 Ribosomal L29 protein APG6_N PF17675.1 EMR64209.1 - 1.6 9.3 7.9 2.7 8.5 7.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Fungal_trans_2 PF11951.8 EMR64210.1 - 1.9e-05 23.6 0.2 0.00035 19.5 0.1 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain eIF3m_C_helix PF18005.1 EMR64210.1 - 0.31 10.8 3.3 3 7.6 0.2 2.9 3 0 0 3 3 3 0 eIF3 subunit M, C-terminal helix Bac_rhamnosid6H PF17389.2 EMR64211.1 - 1.9e-115 385.8 0.0 2.9e-115 385.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EMR64211.1 - 1.3e-51 174.9 0.7 2.1e-51 174.2 0.1 1.7 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 EMR64211.1 - 1.1e-25 89.6 0.0 2.1e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 EMR64211.1 - 8.2e-18 64.0 0.0 2.5e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain GTP1_OBG PF01018.22 EMR64212.1 - 2.1e-34 118.4 4.4 9.6e-27 93.5 6.6 3.9 4 0 0 4 4 4 2 GTP1/OBG MMR_HSR1 PF01926.23 EMR64212.1 - 1.2e-22 80.1 0.0 2.6e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMR64212.1 - 5.1e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EMR64212.1 - 0.0024 16.9 0.0 0.35 9.8 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EMR64212.1 - 0.047 13.1 0.0 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.27 EMR64212.1 - 0.048 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EMR64212.1 - 0.081 13.5 0.1 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3439 PF11921.8 EMR64212.1 - 2.8 7.9 8.2 4.9 7.1 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EMR64212.1 - 3.9 5.6 7.9 5.6 5.0 7.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ABC_tran_CTD PF16326.5 EMR64213.1 - 0.0006 20.0 3.1 0.0006 20.0 3.1 6.3 4 1 2 7 7 7 2 ABC transporter C-terminal domain MOSC PF03473.17 EMR64214.1 - 8.7e-27 93.7 0.1 1.8e-26 92.7 0.1 1.5 1 1 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EMR64214.1 - 2.9e-13 49.8 0.0 6.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain TFCD_C PF12612.8 EMR64215.1 - 1.2e-12 48.1 0.1 1.6e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal RNA_pol_Rpb5_C PF01191.19 EMR64216.1 - 3.6e-32 110.1 0.3 7.4e-32 109.0 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EMR64216.1 - 1.7e-23 83.0 0.0 2.9e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain CENP-B_N PF04218.13 EMR64216.1 - 0.071 12.8 0.1 12 5.6 0.0 2.5 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_CodY PF08222.11 EMR64216.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain eIF3g PF12353.8 EMR64217.1 - 6.6e-44 149.3 5.5 1.1e-43 148.6 5.5 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EMR64217.1 - 5.2e-15 55.0 0.0 9.8e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 EMR64217.1 - 0.0036 17.6 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 EMR64217.1 - 0.036 13.9 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif LEP503 PF15221.6 EMR64218.1 - 0.03 14.6 1.0 0.08 13.3 1.0 1.7 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 DUF1304 PF06993.12 EMR64218.1 - 0.046 13.7 0.2 0.097 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Viral_cys_rich PF08008.12 EMR64218.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.2 2 0 0 2 2 2 0 Viral cysteine rich Phage_holin_3_6 PF07332.11 EMR64218.1 - 0.21 11.6 2.9 2.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4690 PF15756.5 EMR64218.1 - 0.94 10.1 4.1 0.48 11.1 0.9 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage PEMT PF04191.13 EMR64219.1 - 2.7e-56 188.5 7.2 4.7e-34 117.0 0.7 2.4 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 EMR64219.1 - 0.0022 17.8 0.0 0.0061 16.4 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 EMR64219.1 - 0.13 12.8 0.0 3.4 8.3 0.0 2.3 1 1 0 1 1 1 0 SKICH domain fn3_3 PF14686.6 EMR64221.1 - 9.1e-26 89.5 1.7 2.3e-25 88.2 1.7 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 EMR64221.1 - 8.2e-22 77.8 0.1 1.4e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 EMR64221.1 - 0.0018 18.5 0.1 0.065 13.5 0.1 2.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Glyco_hydro_76 PF03663.14 EMR64222.1 - 1.7e-41 143.0 11.7 3.1e-41 142.1 11.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMR64222.1 - 0.0002 20.5 0.6 0.056 12.5 0.0 2.4 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Methyltr_RsmB-F PF01189.17 EMR64223.1 - 1.3e-31 109.9 0.0 2.2e-24 86.2 0.0 3.1 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EMR64223.1 - 0.062 13.4 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase TAF8_C PF10406.9 EMR64224.1 - 1.1 9.9 7.7 0.81 10.3 3.2 2.4 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Pkinase PF00069.25 EMR64225.1 - 3.8e-68 229.7 0.0 4.7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64225.1 - 7.1e-32 110.7 0.0 9.6e-32 110.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMR64225.1 - 1.1e-05 24.5 0.1 1.5e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMR64225.1 - 5.2e-05 22.7 0.1 0.00018 21.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR64225.1 - 0.0004 20.4 0.1 0.0012 18.9 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EMR64225.1 - 0.00073 18.9 0.0 0.073 12.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 EMR64225.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EMR64225.1 - 0.035 13.7 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FAT PF02259.23 EMR64226.1 - 2e-70 237.7 5.0 7.1e-70 235.9 5.0 2.1 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EMR64226.1 - 2.5e-32 112.7 0.0 6.9e-32 111.2 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EMR64226.1 - 6.9e-06 25.8 1.5 8.9e-06 25.4 0.2 2.0 2 0 0 2 2 2 1 FATC domain HEAT PF02985.22 EMR64226.1 - 0.025 14.8 0.2 21 5.7 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat TPR_8 PF13181.6 EMR64226.1 - 0.055 13.7 8.3 0.17 12.1 1.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMR64226.1 - 0.064 13.1 7.4 2.1 8.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMR64226.1 - 0.14 12.4 9.8 2.1 8.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat B56 PF01603.20 EMR64226.1 - 0.14 11.1 7.2 0.15 11.0 0.1 4.3 6 0 0 6 6 6 0 Protein phosphatase 2A regulatory B subunit (B56 family) TPR_17 PF13431.6 EMR64226.1 - 0.67 10.5 2.1 9 6.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NPP1 PF05630.11 EMR64227.1 - 1.3e-63 214.7 0.3 1.5e-63 214.5 0.3 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) GGACT PF06094.12 EMR64228.1 - 9.4e-19 68.2 0.3 1.8e-18 67.3 0.3 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Ribosomal_L5_C PF00673.21 EMR64228.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 ribosomal L5P family C-terminus UDPG_MGDP_dh_N PF03721.14 EMR64229.1 - 9.2e-50 168.8 0.0 1.6e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EMR64229.1 - 6.9e-29 99.9 0.0 1.9e-28 98.5 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EMR64229.1 - 6e-26 90.9 0.0 2.1e-19 69.9 0.0 3.3 2 1 1 3 3 3 3 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 EMR64229.1 - 0.0011 18.8 0.0 0.0045 16.9 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EMR64230.1 - 4e-49 167.8 0.0 5.1e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMR64230.1 - 1.6e-41 142.4 0.0 2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR64230.1 - 2.8e-11 42.9 0.0 3.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMR64230.1 - 5.4e-09 35.6 0.0 0.00047 19.4 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EMR64230.1 - 7e-06 25.4 0.0 0.0058 15.8 0.0 2.3 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMR64230.1 - 1.3e-05 24.5 0.0 0.00021 20.5 0.0 2.3 1 1 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 EMR64230.1 - 0.19 11.6 0.0 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 KR domain Ldh_2 PF02615.14 EMR64231.1 - 5e-124 413.8 0.5 5.7e-124 413.6 0.5 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase 6PF2K PF01591.18 EMR64232.1 - 2.7e-77 259.0 0.0 3.6e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EMR64232.1 - 1.2e-19 70.7 0.0 2.4e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EMR64232.1 - 7.4e-07 29.4 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMR64232.1 - 0.0032 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF816 PF05674.12 EMR64232.1 - 0.03 14.2 0.5 0.061 13.2 0.5 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Adeno_E3_CR1 PF02440.15 EMR64232.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 Ribosomal_S4e PF00900.20 EMR64233.1 - 6.5e-37 125.3 0.1 1.4e-36 124.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EMR64233.1 - 3.3e-23 81.0 0.0 5.8e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EMR64233.1 - 4.2e-18 65.2 6.2 8.2e-18 64.2 6.2 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 EMR64233.1 - 1.5e-05 24.8 2.0 1.5e-05 24.8 2.0 3.0 3 0 0 3 3 3 1 KOW motif S4 PF01479.25 EMR64233.1 - 1.9e-05 24.3 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain Myb_DNA-binding PF00249.31 EMR64234.1 - 1.2e-17 63.8 0.6 2.7e-09 37.1 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR64234.1 - 4.3e-12 46.1 0.6 4.9e-06 26.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EMR64234.1 - 1.8e-05 24.7 0.3 0.22 11.5 0.0 2.5 2 0 0 2 2 2 2 SLIDE Nop16 PF09420.10 EMR64234.1 - 0.00048 20.2 6.7 0.016 15.3 0.0 2.4 2 0 0 2 2 2 1 Ribosome biogenesis protein Nop16 SANT_DAMP1_like PF16282.5 EMR64234.1 - 0.0021 18.2 0.0 0.0058 16.8 0.0 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 CHDCT2 PF08074.11 EMR64234.1 - 0.0027 17.9 0.2 0.0092 16.2 0.2 2.0 2 1 0 2 2 2 1 CHDCT2 (NUC038) domain Sugar_tr PF00083.24 EMR64235.1 - 2.6e-80 270.5 22.8 3.2e-80 270.2 22.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Amidohydro_1 PF01979.20 EMR64235.1 - 1.5e-54 185.6 0.0 3.4e-54 184.5 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family MFS_1 PF07690.16 EMR64235.1 - 3.2e-23 82.2 28.2 1.7e-20 73.3 17.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_3 PF07969.11 EMR64235.1 - 3.8e-13 49.7 0.0 2.9e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family TRI12 PF06609.13 EMR64235.1 - 0.0022 16.5 2.4 0.0034 15.9 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) A_deaminase PF00962.22 EMR64235.1 - 0.0083 15.5 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF4293 PF14126.6 EMR64235.1 - 0.21 11.8 1.2 0.55 10.5 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Alpha-L-AF_C PF06964.12 EMR64236.1 - 2.6e-26 92.7 0.1 7.8e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CorA PF01544.18 EMR64237.1 - 8.8e-05 22.0 1.2 0.00022 20.7 1.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PdxJ PF03740.13 EMR64237.1 - 0.099 11.7 0.2 0.18 10.9 0.2 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Pkinase PF00069.25 EMR64238.1 - 4.4e-73 245.9 0.0 5.1e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64238.1 - 3.4e-37 128.1 0.0 4.1e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR64238.1 - 3.7e-08 33.0 0.0 5.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rad21_Rec8 PF04824.16 EMR64238.1 - 0.19 11.1 0.2 0.41 10.0 0.2 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein HD PF01966.22 EMR64239.1 - 0.00018 21.7 0.0 0.00024 21.3 0.0 1.2 1 0 0 1 1 1 1 HD domain Lectin_leg-like PF03388.13 EMR64240.1 - 2.9e-65 219.8 0.0 3.9e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EMR64240.1 - 5.9e-07 29.7 0.0 8.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EMR64240.1 - 5.2e-05 22.9 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 2 Legume lectin domain PBP1_TM PF14812.6 EMR64240.1 - 0.08 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KA1 PF02149.19 EMR64241.1 - 1.4e-19 69.6 0.1 2.6e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Ribos_L4_asso_C PF14374.6 EMR64241.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain adh_short_C2 PF13561.6 EMR64243.1 - 9e-62 208.7 0.5 1.2e-61 208.3 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR64243.1 - 5.8e-50 169.5 0.3 8.3e-50 169.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR64243.1 - 7.7e-12 45.5 0.1 1.2e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 KR domain PA PF02225.22 EMR64243.1 - 0.00016 21.6 0.1 0.0027 17.7 0.1 2.4 2 0 0 2 2 2 1 PA domain Epimerase PF01370.21 EMR64243.1 - 0.00016 21.2 0.0 0.00033 20.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMR64243.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Patatin PF01734.22 EMR64244.1 - 2.7e-07 31.0 0.0 5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase C1_2 PF03107.16 EMR64244.1 - 0.17 12.3 3.6 0.36 11.2 3.6 1.5 1 0 0 1 1 1 0 C1 domain zf-C3HC4_3 PF13920.6 EMR64244.1 - 0.2 11.5 4.5 0.44 10.5 4.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rcd1 PF04078.13 EMR64245.1 - 2.9e-125 416.8 5.3 4.3e-125 416.2 5.3 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OSCP PF00213.18 EMR64245.1 - 0.18 11.9 3.1 1.2 9.2 0.1 2.8 2 2 0 2 2 2 0 ATP synthase delta (OSCP) subunit Pkinase PF00069.25 EMR64246.1 - 2.3e-50 171.4 0.0 4.8e-29 101.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64246.1 - 1.8e-30 106.1 0.4 2.6e-15 56.4 0.0 2.4 2 1 1 3 3 3 2 Protein tyrosine kinase Borrelia_P83 PF05262.11 EMR64247.1 - 3.1 6.2 10.9 2.3 6.6 2.5 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein PHD PF00628.29 EMR64248.1 - 2.1e-11 43.6 7.3 2.1e-11 43.6 7.3 2.3 2 0 0 2 2 2 1 PHD-finger Ndc1_Nup PF09531.10 EMR64248.1 - 0.065 11.9 0.9 0.08 11.6 0.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FCP1_C PF09309.10 EMR64248.1 - 0.12 12.3 7.2 2.2 8.1 9.9 1.8 2 0 0 2 2 2 0 FCP1, C-terminal Macoilin PF09726.9 EMR64248.1 - 0.85 8.1 10.4 1.2 7.6 10.4 1.2 1 0 0 1 1 1 0 Macoilin family Mucin PF01456.17 EMR64248.1 - 3.1 7.8 16.1 6.6 6.7 16.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Apt1 PF10351.9 EMR64248.1 - 5.8 5.7 10.3 9 5.0 10.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SCO1-SenC PF02630.14 EMR64249.1 - 4.4e-49 165.8 0.0 6.2e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EMR64249.1 - 2.2e-05 24.4 0.0 4.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMR64249.1 - 0.0066 16.2 0.0 0.098 12.4 0.0 2.2 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EMR64249.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like BCA_ABC_TP_C PF12399.8 EMR64249.1 - 0.049 13.6 0.4 0.36 10.8 0.2 2.3 2 1 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter SUIM_assoc PF16619.5 EMR64249.1 - 3.8 7.7 10.0 17 5.6 5.1 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SCIMP PF15050.6 EMR64250.1 - 0.0017 18.9 0.3 0.0017 18.9 0.3 3.1 2 1 1 3 3 3 1 SCIMP protein Choline_kinase PF01633.20 EMR64251.1 - 2.9e-60 203.5 0.0 5.6e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EMR64251.1 - 3e-22 78.0 0.0 5.4e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EMR64251.1 - 0.00057 19.9 0.1 0.0013 18.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cu2_monoox_C PF03712.15 EMR64251.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Hydrolase_like PF13242.6 EMR64252.1 - 5.4e-21 74.4 0.2 3.1e-20 72.0 0.2 2.2 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EMR64252.1 - 1.1e-16 60.8 0.0 2.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR64252.1 - 1.1e-06 29.1 0.0 0.14 12.4 0.0 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR64252.1 - 0.00034 20.8 0.0 0.16 12.0 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Peptidase_M35 PF02102.15 EMR64253.1 - 8.6e-92 307.8 18.3 9.5e-92 307.6 18.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EMR64253.1 - 5.5e-41 140.5 6.1 9.1e-41 139.8 6.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase CARDB PF07705.11 EMR64253.1 - 0.02 15.2 0.0 0.061 13.6 0.0 1.8 1 1 0 1 1 1 0 CARDB DUF3433 PF11915.8 EMR64254.1 - 9.3e-28 96.5 2.0 9.3e-28 96.5 2.0 4.4 6 0 0 6 6 6 2 Protein of unknown function (DUF3433) DFP PF04127.15 EMR64255.1 - 6.8e-14 52.1 0.0 9.9e-06 25.5 0.0 3.4 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein CCDC53 PF10152.9 EMR64255.1 - 0.011 16.1 3.7 0.011 16.1 3.7 2.4 4 0 0 4 4 4 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 EMR64255.1 - 0.024 14.3 11.1 0.044 13.4 11.1 1.4 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 EMR64255.1 - 0.19 12.7 0.1 0.19 12.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Coilin_N PF15862.5 EMR64255.1 - 0.71 9.7 9.5 6.7 6.5 4.9 2.3 2 0 0 2 2 2 0 Coilin N-terminus SpoIIP PF07454.11 EMR64255.1 - 0.87 9.0 5.4 0.91 8.9 0.8 2.7 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) DUF702 PF05142.12 EMR64255.1 - 1.2 9.6 5.2 4.3 7.8 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4746 PF15928.5 EMR64255.1 - 3.2 7.1 11.8 1.6 8.1 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) WSC PF01822.19 EMR64256.1 - 1.2e-11 44.7 5.4 3.4e-11 43.2 5.4 1.9 1 0 0 1 1 1 1 WSC domain ORC6 PF05460.13 EMR64256.1 - 0.25 10.6 3.2 0.5 9.6 3.2 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Macoilin PF09726.9 EMR64256.1 - 0.3 9.6 4.1 0.43 9.1 4.1 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EMR64256.1 - 5.6 5.7 6.4 8.3 5.1 6.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GATA PF00320.27 EMR64257.1 - 9.6e-17 60.3 2.3 1.7e-16 59.5 2.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Peptidase_S28 PF05577.12 EMR64258.1 - 4.4e-41 141.1 5.0 1.2e-39 136.4 0.8 2.5 1 1 1 2 2 2 2 Serine carboxypeptidase S28 Pkinase PF00069.25 EMR64259.1 - 4.3e-61 206.6 0.0 3.9e-60 203.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64259.1 - 2.9e-28 98.9 0.6 5.7e-20 71.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EMR64259.1 - 0.00014 22.5 1.0 0.00063 20.4 1.0 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EMR64259.1 - 0.0077 15.2 0.0 0.014 14.3 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMR64259.1 - 0.0093 15.9 0.2 0.28 11.1 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EMR64259.1 - 0.016 14.5 0.1 0.053 12.8 0.0 1.8 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 EMR64259.1 - 0.031 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FMN_dh PF01070.18 EMR64260.1 - 1.6e-109 366.1 0.0 2.2e-109 365.7 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EMR64260.1 - 2.6e-07 30.1 0.0 4.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EMR64260.1 - 3.4e-05 23.0 0.4 0.00019 20.5 0.2 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMR64260.1 - 0.0069 15.8 0.2 0.01 15.3 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EMR64260.1 - 0.082 12.4 0.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 EMR64260.1 - 0.15 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase CFEM PF05730.11 EMR64261.1 - 0.012 15.7 8.0 0.4 10.8 8.0 2.5 1 1 0 1 1 1 0 CFEM domain Pyrid_oxidase_2 PF13883.6 EMR64262.1 - 3e-44 151.0 0.0 4.8e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3716 PF12511.8 EMR64263.1 - 1.4e-09 37.9 0.6 2.7e-09 36.9 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) zf-RING_6 PF14835.6 EMR64263.1 - 0.36 10.7 8.8 0.41 10.5 6.5 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein adh_short PF00106.25 EMR64264.1 - 1.7e-31 109.2 0.1 3.6e-31 108.1 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64264.1 - 4.1e-20 72.4 0.1 5.6e-20 71.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64264.1 - 4.6e-06 26.7 0.1 6.3e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR64264.1 - 2.4e-05 23.9 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMR64264.1 - 9.3e-05 22.7 0.5 0.00015 22.0 0.5 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EMR64265.1 - 5e-33 113.9 0.1 6.6e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EMR64265.1 - 2.9e-29 101.8 0.0 4.3e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal MFS_1 PF07690.16 EMR64266.1 - 7.1e-36 123.8 48.9 3.9e-29 101.7 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR64266.1 - 8.7e-05 21.6 11.7 8.7e-05 21.6 11.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR64267.1 - 4.9e-38 131.0 42.1 1.9e-37 129.0 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR64267.1 - 2.3e-08 33.4 1.6 4.6e-08 32.3 1.6 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter CnrY PF17524.2 EMR64267.1 - 0.67 10.2 4.1 0.63 10.3 1.1 2.3 2 0 0 2 2 2 0 Anti-sigma factor CnrY DUF1752 PF08550.10 EMR64268.1 - 5.6e-11 42.1 1.4 5.6e-11 42.1 1.4 2.0 2 1 1 3 3 3 1 Fungal protein of unknown function (DUF1752) Wbp11 PF09429.10 EMR64269.1 - 7.5e-24 83.9 8.8 7.5e-24 83.9 8.8 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 Lipoprotein_7 PF01540.16 EMR64269.1 - 0.01 15.1 2.3 0.015 14.6 2.3 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein DegS PF05384.11 EMR64269.1 - 0.055 12.9 0.8 0.086 12.3 0.8 1.2 1 0 0 1 1 1 0 Sensor protein DegS MFS_1 PF07690.16 EMR64270.1 - 7.9e-33 113.8 30.8 7.9e-33 113.8 30.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CD34_antigen PF06365.12 EMR64270.1 - 0.2 11.2 0.1 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family Abhydrolase_1 PF00561.20 EMR64271.1 - 0.0017 18.0 0.1 0.0036 17.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Egh16-like PF11327.8 EMR64272.1 - 6.7e-50 170.1 12.6 6.7e-50 170.1 12.6 2.1 2 1 0 2 2 2 1 Egh16-like virulence factor Izumo-Ig PF16706.5 EMR64272.1 - 0.022 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain I-set PF07679.16 EMR64272.1 - 0.087 12.9 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain Stm1_N PF09598.10 EMR64273.1 - 1.9e-14 54.2 3.7 1.9e-14 54.2 3.7 4.4 5 2 0 5 5 5 1 Stm1 RNA_pol_3_Rpc31 PF11705.8 EMR64274.1 - 0.74 10.0 10.3 1.6 8.9 7.2 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 EMR64274.1 - 9.9 6.6 15.0 0.062 13.7 3.5 3.0 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Peptidase_S10 PF00450.22 EMR64276.1 - 9.3e-88 295.4 0.1 1.2e-87 295.1 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_M20 PF01546.28 EMR64277.1 - 4.8e-27 95.0 0.0 8.5e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR64277.1 - 1.9e-07 31.0 0.0 4.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMR64277.1 - 0.057 13.1 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 MFS_1 PF07690.16 EMR64278.1 - 2.4e-26 92.5 41.0 2.4e-26 92.5 41.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMR64278.1 - 7e-05 22.3 9.5 7e-05 22.3 9.5 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TMEM43 PF07787.12 EMR64278.1 - 4.6 6.6 7.0 8.6 5.7 7.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 43 PA PF02225.22 EMR64279.1 - 9e-13 48.1 0.1 3.5e-12 46.2 0.0 1.9 1 1 1 2 2 2 1 PA domain DUF4804 PF16062.5 EMR64280.1 - 8.8e-81 272.0 0.0 3.9e-47 161.1 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4804) KNOX1 PF03790.13 EMR64280.1 - 0.0088 15.7 0.1 0.028 14.1 0.1 1.8 1 0 0 1 1 1 1 KNOX1 domain GMC_oxred_C PF05199.13 EMR64281.1 - 9.8e-30 104.0 0.0 1.7e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR64281.1 - 2.5e-29 102.6 0.0 4.3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR64281.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HHH PF00633.23 EMR64281.1 - 0.35 10.8 1.2 9.4 6.3 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif GMC_oxred_C PF05199.13 EMR64282.1 - 1.1e-34 120.0 0.0 1.5e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase CorA PF01544.18 EMR64283.1 - 0.00015 21.2 7.7 0.0018 17.7 7.7 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Chitin_synth_1 PF01644.17 EMR64284.1 - 7.1e-74 247.2 0.3 1.1e-73 246.5 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EMR64284.1 - 4.8e-30 103.3 0.0 9e-30 102.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EMR64284.1 - 4.6e-23 81.6 2.2 2.4e-16 59.5 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase SLAC1 PF03595.17 EMR64285.1 - 4.4e-71 239.8 43.6 4.9e-71 239.6 43.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Adeno_E3 PF06040.11 EMR64285.1 - 0.03 14.5 1.3 4.6 7.4 0.1 2.7 3 0 0 3 3 3 0 Adenovirus E3 protein DUF5527 PF17665.1 EMR64285.1 - 1.5 8.3 4.7 10 5.7 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5527) SesA PF17107.5 EMR64286.1 - 0.0096 16.1 0.2 0.016 15.4 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases BAG PF02179.16 EMR64286.1 - 0.075 13.5 1.0 0.11 12.9 1.0 1.6 1 1 0 1 1 1 0 BAG domain Pectate_lyase PF03211.13 EMR64287.1 - 1.4e-83 279.4 7.3 1.7e-83 279.2 7.3 1.0 1 0 0 1 1 1 1 Pectate lyase Pkinase_fungal PF17667.1 EMR64288.1 - 4.4e-74 249.7 0.4 5.7e-74 249.3 0.4 1.1 1 0 0 1 1 1 1 Fungal protein kinase MauJ PF17419.2 EMR64288.1 - 0.027 13.9 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ Actin PF00022.19 EMR64290.1 - 8e-127 423.2 0.0 3.2e-126 421.2 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EMR64290.1 - 0.041 12.7 0.0 6.3 5.5 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein Amidoligase_2 PF12224.8 EMR64292.1 - 5.4e-14 52.5 0.0 2.4e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme zf-CCCH_4 PF18044.1 EMR64294.1 - 2.1e-07 30.6 2.2 3.6e-07 29.8 2.2 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EMR64294.1 - 1.2e-05 25.2 5.0 2e-05 24.5 5.0 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_3 PF15663.5 EMR64294.1 - 0.00034 20.8 0.1 0.00083 19.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 EMR64294.1 - 0.00083 19.2 1.4 0.0015 18.4 1.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EMR64294.1 - 0.0078 16.6 3.5 0.013 16.0 3.5 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EMR64294.1 - 0.013 16.2 1.5 0.036 14.7 0.0 2.6 2 0 0 2 2 2 0 Torus domain DUF3150 PF11348.8 EMR64294.1 - 0.068 12.4 2.8 0.48 9.6 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3150) HNF-1_N PF04814.13 EMR64295.1 - 0.25 11.9 3.2 0.49 11.0 3.2 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus MT0933_antitox PF14013.6 EMR64297.1 - 0.0022 18.2 2.2 0.0048 17.2 1.0 2.0 2 0 0 2 2 2 1 MT0933-like antitoxin protein YtxH PF12732.7 EMR64297.1 - 0.004 17.7 0.2 1.4 9.5 0.1 2.7 2 0 0 2 2 2 1 YtxH-like protein Fig1 PF12351.8 EMR64297.1 - 0.026 14.5 8.9 0.052 13.5 8.9 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 ApoLp-III PF07464.11 EMR64297.1 - 0.05 13.7 0.3 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 EMR64297.1 - 0.083 10.8 0.1 0.23 9.4 0.0 1.7 2 0 0 2 2 2 0 Prominin DUF948 PF06103.11 EMR64297.1 - 0.14 12.4 0.3 0.14 12.4 0.3 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Taeniidae_ag PF05596.11 EMR64297.1 - 0.15 12.1 0.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Taeniidae antigen Baculo_PEP_C PF04513.12 EMR64297.1 - 0.15 12.1 0.2 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_76 PF03663.14 EMR64298.1 - 9.7e-40 137.2 4.9 9.7e-40 137.2 4.9 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMR64298.1 - 1.1e-05 24.7 0.9 0.00022 20.4 0.0 2.9 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 DUF3602 PF12223.8 EMR64299.1 - 2.4e-19 69.7 14.3 3.5e-18 66.0 2.6 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) DUF4719 PF15843.5 EMR64299.1 - 0.62 10.2 2.7 0.58 10.2 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4719) TPR_14 PF13428.6 EMR64300.1 - 5.1e-05 23.8 1.3 0.021 15.6 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR64300.1 - 6.1e-05 22.8 6.6 0.0011 19.0 0.8 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMR64300.1 - 0.00069 19.6 3.0 0.046 14.0 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR64300.1 - 0.0027 18.2 3.5 0.017 15.6 3.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR64300.1 - 0.003 18.2 3.4 0.21 12.2 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR64300.1 - 0.01 16.0 1.7 0.026 14.7 0.8 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EMR64300.1 - 0.012 15.7 1.9 0.092 12.8 0.1 2.7 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 EMR64300.1 - 0.015 15.6 0.4 0.12 12.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMR64300.1 - 0.02 15.2 5.6 0.62 10.4 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMR64300.1 - 0.021 15.4 3.9 0.086 13.5 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EMR64300.1 - 0.024 14.8 1.4 0.67 10.2 0.6 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMR64300.1 - 0.066 13.3 2.4 0.14 12.2 0.3 2.7 3 1 0 3 3 2 0 Tetratricopeptide repeat Glyco_hydro_92 PF07971.12 EMR64300.1 - 0.069 12.1 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 TPR_10 PF13374.6 EMR64300.1 - 0.094 12.6 2.7 12 5.9 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMR64300.1 - 0.12 12.3 1.2 1.7 8.6 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribonucleas_3_3 PF14622.6 EMR64301.1 - 0.00014 22.0 0.3 0.0089 16.2 0.1 2.2 1 1 1 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EMR64301.1 - 0.044 14.4 0.1 0.15 12.7 0.1 1.8 1 1 0 1 1 1 0 Ribonuclease III domain PemK_toxin PF02452.17 EMR64302.1 - 0.18 12.2 0.1 0.42 11.0 0.1 1.6 1 1 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system Carm_PH PF17888.1 EMR64302.1 - 0.24 11.8 0.0 0.37 11.2 0.0 1.2 1 0 0 1 1 1 0 Carmil pleckstrin homology domain Cwf_Cwc_15 PF04889.12 EMR64302.1 - 1.7 8.3 8.9 2.4 7.8 8.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AF-4 PF05110.13 EMR64302.1 - 1.8 6.5 3.6 2.8 5.9 3.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NOA36 PF06524.12 EMR64302.1 - 1.8 7.8 7.4 2.5 7.4 7.4 1.1 1 0 0 1 1 1 0 NOA36 protein Peptidase_M36 PF02128.15 EMR64305.1 - 1.4e-138 462.1 3.7 2e-138 461.6 3.7 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EMR64305.1 - 1.8e-13 50.0 3.3 1.8e-13 50.0 3.3 1.9 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Flavoprotein PF02441.19 EMR64306.1 - 3.1e-30 105.0 0.0 1.3e-25 90.0 0.0 2.6 2 1 0 2 2 2 2 Flavoprotein Sec1 PF00995.23 EMR64307.1 - 4.7e-92 310.1 0.0 7.5e-92 309.4 0.0 1.2 1 0 0 1 1 1 1 Sec1 family DUF1043 PF06295.12 EMR64307.1 - 0.18 11.8 0.8 1.5 8.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) YtxH PF12732.7 EMR64307.1 - 0.62 10.6 2.2 2.5 8.7 2.2 2.1 1 0 0 1 1 1 0 YtxH-like protein PhyH PF05721.13 EMR64309.1 - 4.1e-21 76.2 0.0 6.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pkinase PF00069.25 EMR64310.1 - 3.6e-12 46.2 0.0 1.2e-10 41.2 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64310.1 - 2.6e-07 30.2 0.0 7.2e-06 25.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMR64310.1 - 0.0051 16.8 0.1 0.87 9.5 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family PhyH PF05721.13 EMR64311.1 - 1.9e-29 103.4 0.1 2.5e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 EMR64312.1 - 9.9e-52 176.0 36.8 1.4e-51 175.5 36.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR64312.1 - 1.2e-10 40.9 9.8 1.2e-10 40.9 9.8 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EMR64312.1 - 0.17 10.2 19.1 0.7 8.1 9.3 3.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 EMR64313.1 - 2.7e-13 49.9 0.3 1.5e-11 44.2 0.2 3.0 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR64313.1 - 9.3e-11 41.5 0.4 7.5e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR64313.1 - 7.5e-10 38.9 0.2 6.6e-06 25.9 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR64313.1 - 5.1e-09 35.7 0.1 1.2e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR64313.1 - 1.6e-07 31.4 0.1 7.4e-07 29.3 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR64313.1 - 4.6e-07 29.6 0.3 1.4e-06 28.0 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR64313.1 - 7e-07 28.3 0.0 3.2e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EMR64313.1 - 7.8e-06 25.2 0.1 0.00012 21.3 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EMR64313.1 - 0.0002 20.5 0.2 0.12 11.4 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 EMR64313.1 - 0.00028 21.4 0.1 0.0075 16.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR64313.1 - 0.00073 18.5 0.3 0.1 11.5 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 EMR64313.1 - 0.0025 17.1 0.1 0.007 15.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR64313.1 - 0.0059 15.9 0.7 2.8 7.1 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 EMR64313.1 - 0.0061 15.8 0.0 0.042 13.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 EMR64313.1 - 0.036 14.1 0.5 9.6 6.2 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EMR64313.1 - 0.055 12.8 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMR64313.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EMR64313.1 - 0.22 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 EMR64314.1 - 2.1e-31 109.1 0.0 2.8e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain G_glu_transpept PF01019.21 EMR64315.1 - 7e-134 447.4 0.0 8.1e-134 447.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.16 EMR64318.1 - 8.9e-12 44.6 13.4 4.9e-07 29.0 0.2 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sulfotransfer_4 PF17784.1 EMR64319.1 - 1.4e-56 191.8 0.2 1.7e-56 191.5 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR64319.1 - 0.022 15.2 0.3 0.062 13.7 0.3 1.9 1 1 0 1 1 1 0 Sulfotransferase family Filament PF00038.21 EMR64320.1 - 0.0028 17.3 10.5 0.0029 17.2 6.9 2.0 1 1 0 2 2 2 1 Intermediate filament protein IFT57 PF10498.9 EMR64320.1 - 0.007 15.4 3.0 0.012 14.6 3.0 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Phage_GP20 PF06810.11 EMR64320.1 - 0.014 15.2 4.8 1.7 8.4 0.3 3.1 1 1 0 2 2 2 0 Phage minor structural protein GP20 Occludin_ELL PF07303.13 EMR64320.1 - 0.029 15.1 3.2 1.2 9.9 1.3 2.6 2 0 0 2 2 2 0 Occludin homology domain DWNN PF08783.11 EMR64320.1 - 0.049 13.9 2.9 0.84 10.0 0.1 2.7 2 1 1 3 3 3 0 DWNN domain Sec2p PF06428.11 EMR64320.1 - 0.074 13.0 8.8 0.46 10.5 7.6 2.6 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Type_III_YscX PF09474.10 EMR64320.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.1 2 1 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) PDDEXK_1 PF12705.7 EMR64320.1 - 0.16 11.9 1.8 0.22 11.4 1.8 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DraK_HK_N PF18092.1 EMR64320.1 - 0.24 11.8 4.6 2.2 8.8 0.2 3.1 3 0 0 3 3 3 0 DraK Histidine Kinase N-terminal domain DUF3450 PF11932.8 EMR64320.1 - 0.27 10.5 7.6 0.54 9.5 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spectrin PF00435.21 EMR64320.1 - 0.33 11.4 7.4 0.6 10.6 3.7 2.7 1 1 2 3 3 3 0 Spectrin repeat PRKG1_interact PF15898.5 EMR64320.1 - 0.37 11.7 9.1 0.13 13.2 5.1 2.1 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FlxA PF14282.6 EMR64320.1 - 0.38 10.8 7.5 0.95 9.5 6.7 2.0 2 1 0 2 2 2 0 FlxA-like protein Spc7 PF08317.11 EMR64320.1 - 0.46 9.3 9.6 0.64 8.8 6.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein MbeD_MobD PF04899.12 EMR64320.1 - 0.5 10.5 4.6 4.7 7.4 1.0 2.6 1 1 1 2 2 2 0 MbeD/MobD like Fib_alpha PF08702.10 EMR64320.1 - 0.56 10.4 8.2 0.41 10.8 3.8 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4446 PF14584.6 EMR64320.1 - 0.6 10.1 3.0 1.2 9.1 1.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) YabA PF06156.13 EMR64320.1 - 0.72 10.5 4.4 1.9 9.2 2.6 2.2 2 1 0 2 2 2 0 Initiation control protein YabA DUF1043 PF06295.12 EMR64320.1 - 0.89 9.6 10.0 23 5.0 6.7 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1043) Exonuc_VII_L PF02601.15 EMR64320.1 - 1.3 8.5 10.1 2.4 7.7 10.1 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 EMR64320.1 - 1.5 7.7 3.0 1.6 7.5 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Fzo_mitofusin PF04799.13 EMR64320.1 - 1.7 8.1 6.5 6.6 6.3 1.0 2.8 2 1 1 3 3 3 0 fzo-like conserved region DUF16 PF01519.16 EMR64320.1 - 2 8.9 6.0 1.7 9.1 3.0 2.2 1 1 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 EMR64320.1 - 5.8 7.0 9.1 7.2 6.7 4.0 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EMR64320.1 - 5.9 6.2 8.5 9.4 5.5 8.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Glutaredoxin PF00462.24 EMR64321.1 - 1.4e-14 54.1 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin PRELI PF04707.14 EMR64322.1 - 1.2e-23 83.7 0.6 1.2e-20 73.9 0.2 2.1 2 0 0 2 2 2 2 PRELI-like family Aldo_ket_red PF00248.21 EMR64323.1 - 7.6e-71 238.7 0.0 8.6e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase PF00702.26 EMR64323.1 - 0.0061 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Caps_synth PF05704.12 EMR64324.1 - 2e-09 37.3 0.0 4.7e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 EMR64324.1 - 0.0005 20.6 0.0 0.001 19.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Fe-S_biosyn PF01521.20 EMR64325.1 - 2.4e-19 69.6 0.0 3.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ndc1_Nup PF09531.10 EMR64325.1 - 0.95 8.1 8.6 1.1 7.9 8.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aa_trans PF01490.18 EMR64326.1 - 8.4e-16 57.7 9.0 9.8e-16 57.4 9.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 EMR64327.1 - 1.5e-10 40.5 33.4 5e-07 29.0 13.4 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily GMC_oxred_C PF05199.13 EMR64328.1 - 3.6e-16 60.0 0.0 6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR64328.1 - 0.0009 18.7 0.1 0.019 14.4 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EMR64328.1 - 0.0013 18.0 0.0 0.0034 16.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR64328.1 - 0.004 17.4 0.0 0.0088 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR64328.1 - 0.045 12.8 0.0 0.089 11.9 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EMR64328.1 - 0.058 13.0 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Aminotran_3 PF00202.21 EMR64329.1 - 2.4e-82 276.8 0.0 2.9e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fer2_2 PF01799.20 EMR64329.1 - 0.1 12.6 3.2 2.5 8.2 0.1 2.7 2 1 0 2 2 2 0 [2Fe-2S] binding domain DUF1741 PF08427.10 EMR64330.1 - 6.7e-88 294.3 0.0 1.1e-87 293.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DUF3632 PF12311.8 EMR64331.1 - 1.6e-23 84.0 6.7 1.6e-23 84.0 6.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) eIF3m_C_helix PF18005.1 EMR64331.1 - 0.041 13.6 0.5 0.041 13.6 0.5 1.9 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Serglycin PF04360.12 EMR64332.1 - 0.0052 16.7 2.5 0.012 15.5 2.5 1.6 1 0 0 1 1 1 1 Serglycin FeoB_Cyto PF17910.1 EMR64332.1 - 0.014 15.9 0.5 0.25 11.9 0.1 2.4 2 0 0 2 2 2 0 FeoB cytosolic helical domain Pkinase PF00069.25 EMR64333.1 - 1.1e-57 195.4 0.0 9e-52 176.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64333.1 - 5.8e-35 120.8 0.0 1.9e-33 115.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR64333.1 - 1.1e-07 31.5 0.0 5.4e-07 29.2 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EMR64333.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMR64333.1 - 0.00051 18.9 0.0 0.0012 17.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EMR64333.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MuF_C PF18819.1 EMR64333.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Phage MuF-C-terminal domain p450 PF00067.22 EMR64334.1 - 1.5e-08 33.8 0.0 7.6e-08 31.5 0.0 1.8 1 1 1 2 2 2 1 Cytochrome P450 OPT PF03169.15 EMR64335.1 - 9.9e-28 97.1 0.0 1.3e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GCN5L1 PF06320.13 EMR64336.1 - 4.2e-15 55.9 1.9 4.3e-15 55.9 0.5 1.7 1 1 1 2 2 2 1 GCN5-like protein 1 (GCN5L1) TFIIA PF03153.13 EMR64336.1 - 0.041 13.9 14.7 0.12 12.3 14.7 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serglycin PF04360.12 EMR64336.1 - 0.99 9.3 14.6 1.3 9.0 12.4 2.2 1 1 1 2 2 2 0 Serglycin Steroid_dh PF02544.16 EMR64337.1 - 4.8e-29 101.3 1.7 8e-29 100.6 1.7 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EMR64337.1 - 0.046 14.1 1.3 0.097 13.1 0.2 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase DUF1295 PF06966.12 EMR64337.1 - 0.061 12.8 0.3 0.098 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) p450 PF00067.22 EMR64338.1 - 1e-34 120.1 0.0 1.1e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trypsin_2 PF13365.6 EMR64339.1 - 9.7e-13 49.3 0.1 1.6e-12 48.5 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EMR64339.1 - 1.1e-09 38.4 0.0 2.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin Sec5 PF15469.6 EMR64339.1 - 0.17 11.7 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 4HBT_3 PF13622.6 EMR64340.1 - 2.2e-34 119.9 0.8 2.5e-34 119.7 0.8 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Med13_C PF06333.12 EMR64340.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain ATP-synt_DE_N PF02823.16 EMR64340.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HET PF06985.11 EMR64341.1 - 3.3e-10 40.5 0.1 1.1e-06 29.0 0.0 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) CinA PF02464.17 EMR64342.1 - 6e-35 120.1 2.3 6.8e-35 119.9 2.3 1.0 1 0 0 1 1 1 1 Competence-damaged protein FSH1 PF03959.13 EMR64343.1 - 1e-15 58.0 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PGP_phosphatase PF09419.10 EMR64344.1 - 4.6e-36 124.0 0.0 5.6e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EMR64344.1 - 6e-06 26.2 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like p450 PF00067.22 EMR64345.1 - 1.3e-39 136.2 0.1 7e-24 84.4 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 FAD_binding_3 PF01494.19 EMR64345.1 - 5.3e-12 45.7 0.7 1.9e-05 24.1 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 EMR64345.1 - 0.0024 17.2 0.0 0.7 9.1 0.0 2.4 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EMR64345.1 - 0.012 14.8 0.3 0.022 13.9 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EMR64345.1 - 0.013 15.1 0.3 0.42 10.1 0.2 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR64345.1 - 0.023 14.9 0.1 0.065 13.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMR64345.1 - 0.082 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 EMR64345.1 - 0.087 12.0 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CVNH PF08881.10 EMR64346.1 - 4.4e-28 97.9 0.1 4.9e-28 97.8 0.1 1.0 1 0 0 1 1 1 1 CVNH domain DUF4097 PF13349.6 EMR64346.1 - 0.03 13.7 0.0 2.5 7.4 0.1 2.0 1 1 1 2 2 2 0 Putative adhesin ArgJ PF01960.18 EMR64348.1 - 2.5e-143 477.4 0.3 3.6e-143 476.8 0.3 1.2 1 0 0 1 1 1 1 ArgJ family Rep_fac_C PF08542.11 EMR64348.1 - 1.7e-22 79.6 0.0 4.3e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EMR64348.1 - 4.6e-11 42.8 0.0 4e-08 33.2 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EMR64348.1 - 8.2e-11 42.5 0.0 1.7e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EMR64348.1 - 2.9e-06 27.3 0.0 6.8e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR64348.1 - 1.8e-05 25.2 0.0 0.00063 20.2 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMR64348.1 - 0.0003 21.1 0.1 0.31 11.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EMR64348.1 - 0.00051 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EMR64348.1 - 0.00081 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EMR64348.1 - 0.0014 18.5 0.0 0.0045 16.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 EMR64348.1 - 0.0042 17.4 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 EMR64348.1 - 0.011 15.1 0.0 0.051 13.0 0.0 1.9 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 EMR64348.1 - 0.031 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit MeaB PF03308.16 EMR64348.1 - 0.035 13.1 0.0 0.064 12.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 EMR64348.1 - 0.07 12.5 0.0 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_11 PF13086.6 EMR64348.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMR64348.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RGS12_usC PF16612.5 EMR64348.1 - 0.1 13.1 0.7 0.51 10.8 0.0 2.1 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 AAA_5 PF07728.14 EMR64348.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EMR64348.1 - 0.12 12.7 0.1 0.36 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMR64348.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 EMR64348.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain KR PF08659.10 EMR64351.1 - 5.6e-46 156.7 0.2 4.2e-27 95.2 0.1 2.6 1 1 1 2 2 2 2 KR domain PS-DH PF14765.6 EMR64351.1 - 1.9e-30 106.2 0.0 2.9e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EMR64351.1 - 1.1e-17 65.4 0.0 3.1e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR64351.1 - 1.4e-16 60.6 0.0 5.3e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EMR64351.1 - 4.9e-07 30.4 0.0 1.2e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR64351.1 - 1.7e-06 28.2 0.0 4.8e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EMR64351.1 - 1.6e-05 24.8 0.3 3.7e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_33 PF10017.9 EMR64351.1 - 0.00081 18.6 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 EMR64351.1 - 0.0014 19.3 0.2 0.0068 17.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 EMR64351.1 - 0.0025 17.3 0.1 0.028 13.9 0.0 2.4 1 1 1 2 2 2 1 short chain dehydrogenase Methyltransf_28 PF02636.17 EMR64351.1 - 0.11 12.1 0.0 0.36 10.4 0.0 1.8 3 0 0 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 EMR64351.1 - 0.14 11.2 0.0 0.45 9.5 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 EMR64351.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Mitofilin PF09731.9 EMR64352.1 - 0.075 11.9 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Methyltransf_2 PF00891.18 EMR64353.1 - 1.5e-18 66.9 0.0 4.1e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 EMR64353.1 - 0.038 13.8 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain CAP59_mtransfer PF11735.8 EMR64355.1 - 0.058 13.1 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 GFA PF04828.14 EMR64356.1 - 1.1e-05 25.6 1.3 1.1e-05 25.6 1.3 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Myticin-prepro PF10690.9 EMR64356.1 - 2 8.7 6.0 0.54 10.5 2.9 1.6 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel CutC PF03932.14 EMR64357.1 - 4.4e-29 101.4 1.7 2.5e-15 56.5 0.1 3.5 3 1 0 3 3 3 3 CutC family His_biosynth PF00977.21 EMR64357.1 - 0.045 13.2 0.1 0.083 12.3 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DER1 PF04511.15 EMR64358.1 - 5.4e-11 42.8 0.5 6.2e-11 42.6 0.5 1.0 1 0 0 1 1 1 1 Der1-like family TatC PF00902.18 EMR64358.1 - 0.011 15.6 4.9 0.014 15.2 4.9 1.1 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) SSPI PF14098.6 EMR64358.1 - 0.18 11.9 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Small, acid-soluble spore protein I ORC2 PF04084.14 EMR64359.1 - 2.9e-117 391.3 0.0 3.6e-117 391.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 MS_channel PF00924.18 EMR64360.1 - 9.3e-21 74.3 1.2 1.8e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 EMR64360.1 - 0.011 15.6 0.0 0.31 11.1 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EMR64360.1 - 0.035 14.6 0.0 0.13 12.7 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 EMR64360.1 - 0.047 13.2 0.3 0.12 12.0 0.3 1.8 1 0 0 1 1 1 0 EF hand Cytochrom_B_N_2 PF13631.6 EMR64360.1 - 8.4 6.4 8.7 0.45 10.5 2.1 2.0 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB FAD_binding_4 PF01565.23 EMR64361.1 - 2.3e-20 72.7 1.5 4.6e-20 71.8 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR64361.1 - 1.3e-06 28.4 0.3 3e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like NmrA PF05368.13 EMR64362.1 - 1.4e-35 123.0 0.1 1.7e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR64362.1 - 3e-20 72.9 0.6 3.8e-20 72.5 0.6 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR64362.1 - 0.00021 20.9 0.2 0.00073 19.1 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR64362.1 - 0.0017 17.4 0.1 0.0029 16.7 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EMR64362.1 - 0.0036 17.3 0.3 0.011 15.6 0.2 1.8 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EMR64362.1 - 0.012 15.0 0.0 0.039 13.4 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EMR64362.1 - 0.012 15.8 0.3 0.019 15.2 0.3 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3798 PF12683.7 EMR64362.1 - 0.088 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Polysacc_synt_2 PF02719.15 EMR64362.1 - 0.15 11.1 0.0 1.5 7.9 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PI-PLC-X PF00388.19 EMR64365.1 - 4.1e-56 188.6 0.0 8.1e-56 187.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EMR64365.1 - 4.1e-42 143.2 0.2 1.4e-41 141.4 0.2 2.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EMR64365.1 - 5.1e-07 29.9 0.1 1.9e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 C2 domain PH_12 PF16457.5 EMR64365.1 - 1.8e-05 25.3 0.1 1.8e-05 25.3 0.1 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain EF-hand_7 PF13499.6 EMR64365.1 - 0.00044 20.6 0.1 0.0027 18.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair PH PF00169.29 EMR64365.1 - 0.0013 19.2 0.9 0.0029 18.1 0.2 2.0 2 0 0 2 2 2 1 PH domain EF-hand_1 PF00036.32 EMR64365.1 - 0.0036 16.7 0.2 0.019 14.5 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.11 EMR64365.1 - 0.0094 16.4 0.1 0.055 13.9 0.0 2.3 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 EMR64365.1 - 0.0096 15.8 1.7 0.032 14.2 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain Mcp5_PH PF12814.7 EMR64365.1 - 0.075 13.2 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Benyvirus_P25 PF05744.11 EMR64365.1 - 0.084 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Benyvirus P25/P26 protein MnmE_helical PF12631.7 EMR64366.1 - 2.2e-26 93.3 0.0 5.1e-20 72.5 0.0 2.7 2 1 0 2 2 2 2 MnmE helical domain TrmE_N PF10396.9 EMR64366.1 - 7.5e-22 77.8 0.1 2.3e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EMR64366.1 - 1.9e-18 66.6 0.0 5.6e-18 65.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMR64366.1 - 2e-05 24.2 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EMR64366.1 - 6.1e-05 23.1 0.0 9.2e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 EMR64366.1 - 0.0022 17.9 0.0 0.0087 16.0 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EMR64366.1 - 0.013 15.1 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EMR64366.1 - 0.033 14.7 0.0 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 EMR64366.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.7 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EMR64366.1 - 0.057 13.1 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMR64366.1 - 0.085 13.1 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NMO PF03060.15 EMR64367.1 - 2.5e-48 165.2 6.5 4.2e-48 164.4 6.5 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EMR64367.1 - 3e-07 29.8 8.1 1.9e-06 27.2 8.1 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EMR64367.1 - 0.00038 19.6 9.4 0.0006 19.0 9.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EMR64367.1 - 0.21 10.7 7.0 0.34 10.0 7.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase FlpD PF02662.16 EMR64367.1 - 1.2 9.1 3.4 3.3 7.7 0.3 2.4 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit UQ_con PF00179.26 EMR64368.1 - 1.5e-49 167.2 0.0 1.7e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pmp3 PF01679.17 EMR64369.1 - 3.7e-20 71.9 8.6 4.5e-20 71.6 8.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ribosomal_L28e PF01778.17 EMR64370.1 - 1.8e-40 138.3 3.6 3.5e-40 137.3 2.2 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EMR64370.1 - 8.8e-29 100.1 20.4 8.8e-29 100.1 20.4 2.2 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EMR64370.1 - 0.00037 20.0 15.8 0.00053 19.5 15.8 1.2 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EMR64370.1 - 0.01 15.6 1.7 0.018 14.8 1.7 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain Methyltransf_11 PF08241.12 EMR64371.1 - 0.0024 18.5 0.0 0.0042 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR64371.1 - 0.01 16.5 0.0 0.023 15.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EMR64371.1 - 0.15 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family BCS1_N PF08740.11 EMR64372.1 - 2.6e-36 125.3 0.1 2.6e-36 125.3 0.1 1.6 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 EMR64372.1 - 4.1e-19 69.3 0.0 3.6e-10 40.4 0.0 2.6 1 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR64372.1 - 0.00067 20.1 0.0 0.011 16.1 0.0 2.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_28 PF13521.6 EMR64372.1 - 0.0078 16.5 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMR64372.1 - 0.0096 15.9 0.0 0.032 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMR64372.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EMR64372.1 - 0.019 14.5 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EMR64372.1 - 0.024 14.0 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 EMR64372.1 - 0.025 15.1 0.0 0.077 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EMR64372.1 - 0.033 13.4 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 EMR64372.1 - 0.058 13.8 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EMR64372.1 - 0.099 12.8 0.0 0.27 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain IPT PF01745.16 EMR64372.1 - 0.17 11.2 0.0 0.4 10.0 0.0 1.6 2 0 0 2 2 2 0 Isopentenyl transferase AAA_6 PF12774.7 EMR64372.1 - 0.18 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_11 PF13086.6 EMR64372.1 - 0.26 11.1 2.3 1.1 9.0 2.3 2.1 1 1 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.11 EMR64372.1 - 1.3 7.8 4.1 22 3.8 0.0 2.2 1 1 1 2 2 2 0 Polyomavirus large T antigen C-terminus DHHC PF01529.20 EMR64374.1 - 9.8e-37 126.1 10.8 1.4e-36 125.5 10.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase zinc_ribbon_2 PF13240.6 EMR64374.1 - 1.3 8.8 3.6 2.7 7.8 3.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain YfhO PF09586.10 EMR64374.1 - 7.5 4.6 6.6 0.25 9.5 0.5 1.5 2 0 0 2 2 2 0 Bacterial membrane protein YfhO adh_short PF00106.25 EMR64375.1 - 8.4e-31 106.9 0.0 1.2e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64375.1 - 3.4e-21 75.9 0.0 5.7e-21 75.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64375.1 - 0.1 12.5 0.1 0.67 9.8 0.1 2.1 1 1 0 1 1 1 0 KR domain UQ_con PF00179.26 EMR64376.1 - 2.7e-18 66.0 0.0 4.2e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EMR64376.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 RWD domain MCM PF00493.23 EMR64377.1 - 4.6e-106 352.9 0.1 1.1e-105 351.7 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EMR64377.1 - 1.1e-35 122.3 0.1 2e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EMR64377.1 - 1.3e-28 99.2 1.4 3.2e-28 98.0 1.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMR64377.1 - 1e-14 55.0 0.6 3.1e-14 53.4 0.6 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMR64377.1 - 7.1e-07 28.8 0.0 0.0002 20.8 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMR64377.1 - 3.6e-05 23.8 0.0 7.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EMR64377.1 - 0.00026 20.9 0.0 0.0013 18.6 0.0 2.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EMR64377.1 - 0.022 15.2 0.8 0.42 11.0 0.0 3.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMR64377.1 - 0.047 13.4 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain CorA PF01544.18 EMR64377.1 - 0.077 12.3 0.4 0.14 11.5 0.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein F-box-like PF12937.7 EMR64378.1 - 0.0016 18.3 0.2 0.0038 17.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR64378.1 - 0.0094 15.8 0.2 0.022 14.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EMR64378.1 - 0.11 13.0 0.1 22 5.7 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) FAD_binding_3 PF01494.19 EMR64379.1 - 5.3e-09 35.8 6.9 0.00046 19.5 3.2 3.5 3 1 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EMR64379.1 - 0.0024 18.0 0.6 0.014 15.6 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMR64379.1 - 0.014 15.4 0.2 0.031 14.3 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding p450 PF00067.22 EMR64380.1 - 9.3e-33 113.7 0.4 3.6e-32 111.7 0.4 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF4611 PF15387.6 EMR64380.1 - 2.1 8.6 4.0 21 5.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) adh_short PF00106.25 EMR64381.1 - 1.3e-25 90.0 0.1 2e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64381.1 - 7e-20 71.6 0.1 8.5e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64381.1 - 9e-08 32.2 0.1 1.3e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR64381.1 - 3.5e-07 30.3 0.3 3.9e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR64381.1 - 6.2e-05 22.6 0.1 9.9e-05 21.9 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Vps54 PF07928.12 EMR64383.1 - 4.6e-53 179.2 0.3 9.3e-53 178.2 0.1 1.6 2 0 0 2 2 2 1 Vps54-like protein DUF1996 PF09362.10 EMR64385.1 - 1.4e-75 254.3 3.0 1.7e-75 254.1 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-C2H2 PF00096.26 EMR64386.1 - 1e-13 50.9 14.1 0.0054 17.1 1.0 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR64386.1 - 5.2e-13 48.6 13.3 0.019 15.8 0.6 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMR64386.1 - 2.9e-12 46.5 8.8 0.0089 16.3 1.0 5.4 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMR64386.1 - 2.9e-09 37.0 10.9 0.019 15.4 0.2 5.3 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 EMR64386.1 - 1e-07 32.1 18.9 5.2e-05 23.5 1.9 3.6 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EMR64386.1 - 9.2e-06 25.9 17.8 0.35 11.2 0.9 4.4 2 2 2 4 4 4 3 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 EMR64386.1 - 0.00021 21.7 7.9 0.29 11.7 0.1 5.2 5 0 0 5 5 5 1 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 EMR64386.1 - 0.00053 20.3 20.5 0.76 10.3 0.2 5.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-WRNIP1_ubi PF18279.1 EMR64386.1 - 0.00071 20.0 4.2 6.6 7.6 0.0 4.7 4 0 0 4 4 4 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_8 PF15909.5 EMR64386.1 - 0.0084 16.4 7.4 0.27 11.5 0.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc ribbon zf-CRD PF17979.1 EMR64386.1 - 0.017 15.2 1.0 0.017 15.2 1.0 2.7 2 1 1 3 3 3 0 Cysteine rich domain with multizinc binding regions TRAF6_Z2 PF18048.1 EMR64386.1 - 0.027 14.6 1.2 1.7 8.8 0.1 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_9 PF16293.5 EMR64386.1 - 0.034 14.0 0.3 0.034 14.0 0.3 4.0 4 1 1 5 5 4 0 C2H2 type zinc-finger (1 copy) IBR PF01485.21 EMR64386.1 - 0.047 13.9 9.8 1.8 8.8 0.5 3.4 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain FdhE PF04216.12 EMR64386.1 - 0.078 12.9 1.7 0.095 12.6 0.4 1.7 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation FOXP-CC PF16159.5 EMR64386.1 - 0.086 13.5 4.6 23 5.7 0.3 4.1 2 2 1 3 3 3 0 FOXP coiled-coil domain zf-LITAF-like PF10601.9 EMR64386.1 - 0.088 13.1 8.0 0.76 10.1 2.3 2.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zinc_ribbon_4 PF13717.6 EMR64386.1 - 0.099 12.6 21.2 3.3 7.7 0.6 5.2 4 1 1 5 5 5 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EMR64386.1 - 0.12 12.5 9.1 4.1 7.6 1.0 3.5 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 EMR64386.1 - 0.18 12.5 3.1 1.2 9.9 0.5 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 EMR64386.1 - 0.48 10.2 2.8 17 5.2 0.0 2.8 3 0 0 3 3 2 0 zinc-finger C2H2-type FYDLN_acid PF09538.10 EMR64386.1 - 0.62 10.8 3.7 20 5.9 0.1 3.7 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Prok-RING_1 PF14446.6 EMR64386.1 - 0.67 9.9 14.4 6.2 6.8 2.4 4.4 3 2 1 4 4 4 0 Prokaryotic RING finger family 1 DUF2225 PF09986.9 EMR64386.1 - 0.72 9.5 12.6 3.7 7.2 1.7 3.8 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) PHD_4 PF16866.5 EMR64386.1 - 1.7 8.8 7.9 2.3 8.4 1.0 3.3 2 1 1 3 3 3 0 PHD-finger CpXC PF14353.6 EMR64386.1 - 2.1 8.4 11.8 15 5.6 0.1 4.3 2 2 3 5 5 5 0 CpXC protein zinc_ribbon_15 PF17032.5 EMR64386.1 - 3.2 8.6 8.4 8.3 7.2 1.2 3.4 2 1 1 3 3 3 0 zinc-ribbon family zf-C6H2 PF15801.5 EMR64386.1 - 4.6 7.6 12.6 23 5.4 0.1 4.5 5 0 0 5 5 4 0 zf-MYND-like zinc finger, mRNA-binding RNA_POL_M_15KD PF02150.16 EMR64386.1 - 5.3 7.0 5.9 3.2 7.7 0.0 3.4 5 0 0 5 5 5 0 RNA polymerases M/15 Kd subunit zf-DNA_Pol PF08996.10 EMR64386.1 - 5.4 6.7 10.2 3.9 7.2 1.0 2.6 2 1 0 2 2 2 0 DNA Polymerase alpha zinc finger zinc_ribbon_12 PF11331.8 EMR64386.1 - 5.7 6.8 9.8 7.5 6.4 0.1 4.1 3 1 1 4 4 4 0 Probable zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EMR64386.1 - 7.6 6.5 11.1 1 9.4 0.6 3.6 3 1 0 3 3 3 0 Putative transposase DNA-binding domain Gloverin PF10793.9 EMR64388.1 - 1.3 8.9 9.8 7 6.5 5.9 2.8 1 1 1 2 2 2 0 Gloverin-like protein FARP PF01581.16 EMR64388.1 - 6.6 7.7 10.6 80 4.5 0.6 4.2 4 0 0 4 4 4 0 FMRFamide related peptide family DUF2293 PF10056.9 EMR64389.1 - 1.7e-25 89.1 1.9 1.7e-25 89.1 1.9 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) DUF3235 PF11574.8 EMR64389.1 - 0.079 13.8 1.5 0.15 12.9 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) THOC7 PF05615.13 EMR64389.1 - 1.1 9.5 6.0 8.5 6.7 6.1 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 FAD_binding_1 PF00667.20 EMR64390.1 - 5e-45 153.8 0.0 7.3e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EMR64390.1 - 1.7e-09 38.3 0.0 4.7e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_4 PF01565.23 EMR64391.1 - 3.8e-11 42.9 1.6 6.9e-11 42.0 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR64391.1 - 4.2e-11 42.8 0.8 7.7e-11 41.9 0.8 1.4 1 0 0 1 1 1 1 Berberine and berberine like DUF2129 PF09902.9 EMR64391.1 - 0.027 14.6 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) FAD_binding_4 PF01565.23 EMR64393.1 - 1.5e-29 102.6 0.2 2.6e-29 101.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DUF4185 PF13810.6 EMR64397.1 - 2e-10 40.4 0.1 2.9e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Pkinase PF00069.25 EMR64398.1 - 4.5e-06 26.2 0.0 0.0045 16.4 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64398.1 - 0.0021 17.4 0.0 0.037 13.3 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Phage_min_cap2 PF06152.11 EMR64398.1 - 0.021 13.7 2.9 0.031 13.2 2.9 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Polyketide_cyc2 PF10604.9 EMR64400.1 - 1.2e-16 61.3 0.2 1.5e-16 61.0 0.2 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ADH_zinc_N PF00107.26 EMR64401.1 - 9e-11 41.9 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR64401.1 - 1.4e-08 34.5 0.0 7.1e-08 32.3 0.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.25 EMR64406.1 - 9.3e-32 110.4 0.0 1.4e-22 80.3 0.4 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64406.1 - 8.5e-12 44.9 0.7 2.7e-10 40.0 0.1 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR64406.1 - 0.027 13.2 1.0 0.073 11.8 1.0 1.8 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EMR64406.1 - 0.13 11.8 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Med3 PF11593.8 EMR64408.1 - 1.2 8.2 8.8 2.3 7.3 8.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med26 PF08711.11 EMR64409.1 - 4.3e-11 42.7 0.0 1.2e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF5309 PF17236.2 EMR64409.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5309) Fungal_trans PF04082.18 EMR64410.1 - 3.7e-17 62.2 0.1 5.8e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEPN_SAV_6107 PF18726.1 EMR64410.1 - 0.078 13.5 0.3 0.64 10.6 0.1 2.3 2 0 0 2 2 2 0 SAV_6107-like HEPN DnaA_N PF11638.8 EMR64410.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 DnaA N-terminal domain adh_short PF00106.25 EMR64411.1 - 2.5e-17 63.0 0.0 5.7e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMR64411.1 - 5.6e-07 29.6 0.0 8.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Brr6_like_C_C PF10104.9 EMR64412.1 - 6.6e-32 110.1 0.2 1.1e-31 109.4 0.2 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF4263 PF14082.6 EMR64412.1 - 0.04 14.2 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) FeoB_associated PF12669.7 EMR64412.1 - 0.27 11.7 1.1 0.61 10.5 1.1 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF5542 PF17696.1 EMR64412.1 - 1.2 9.3 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5542) SPAN PF02510.14 EMR64412.1 - 4.9 6.2 8.8 0.63 9.2 0.0 2.3 2 0 0 2 2 2 0 Surface presentation of antigens protein p450 PF00067.22 EMR64413.1 - 9.6e-55 186.1 0.0 1.3e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pim PF16765.5 EMR64413.1 - 0.061 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Pesticin immunity protein DUF3336 PF11815.8 EMR64414.1 - 4.5e-46 156.0 1.4 6.8e-46 155.4 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EMR64414.1 - 4.8e-18 66.1 0.2 2.3e-13 50.8 0.4 2.8 2 1 0 3 3 3 2 Patatin-like phospholipase GHMP_kinases_C PF08544.13 EMR64414.1 - 0.11 12.9 0.3 42 4.6 0.0 3.5 3 1 1 4 4 4 0 GHMP kinases C terminal DEAD PF00270.29 EMR64416.1 - 1.9e-42 145.0 0.2 3.1e-42 144.3 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR64416.1 - 2.6e-33 114.7 0.0 9.6e-33 112.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EMR64416.1 - 0.00051 19.8 0.1 0.00077 19.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EMR64416.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EMR64416.1 - 0.0013 19.1 0.1 0.011 16.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF5393 PF17371.2 EMR64416.1 - 0.049 11.7 0.1 0.078 11.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Flavi_DEAD PF07652.14 EMR64416.1 - 0.055 13.4 0.3 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 EMR64416.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 EMR64416.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 EMR64416.1 - 0.14 12.4 0.9 0.67 10.2 0.9 2.0 1 1 0 1 1 1 0 AAA domain Amino_oxidase PF01593.24 EMR64418.1 - 8.8e-12 45.0 0.0 1.5e-11 44.3 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR64418.1 - 4.4e-08 33.3 0.2 1.4e-07 31.7 0.2 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR64418.1 - 0.0026 17.4 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR64418.1 - 0.0072 15.4 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMR64418.1 - 0.0097 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EMR64418.1 - 0.035 13.3 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR64418.1 - 0.085 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Rrp15p PF07890.12 EMR64419.1 - 1.1e-36 126.1 3.8 1.1e-36 126.1 3.8 2.8 2 1 0 2 2 2 1 Rrp15p CAF1A PF12253.8 EMR64419.1 - 0.005 17.0 0.5 0.005 17.0 0.5 2.5 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A Macoilin PF09726.9 EMR64419.1 - 5.8 5.3 17.7 8 4.9 17.7 1.2 1 0 0 1 1 1 0 Macoilin family K_trans PF02705.16 EMR64420.1 - 8.1e-158 526.2 1.6 9.9e-158 526.0 1.6 1.1 1 0 0 1 1 1 1 K+ potassium transporter Macoilin PF09726.9 EMR64421.1 - 0.017 13.7 6.5 0.021 13.4 6.5 1.1 1 0 0 1 1 1 0 Macoilin family GrpE PF01025.19 EMR64421.1 - 0.12 12.0 4.9 0.21 11.3 4.9 1.3 1 0 0 1 1 1 0 GrpE DUF2203 PF09969.9 EMR64421.1 - 0.29 11.9 2.8 0.49 11.1 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Mito_carr PF00153.27 EMR64422.1 - 2.1e-14 53.2 1.0 4.5e-05 23.3 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_47 PF01532.20 EMR64423.1 - 2.8e-172 573.7 0.0 3.3e-172 573.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fer2 PF00111.27 EMR64424.1 - 2.4e-12 46.6 0.6 3.1e-12 46.3 0.6 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 EMR64426.1 - 2.8e-55 184.2 4.2 9.1e-19 67.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3449 PF11931.8 EMR64427.1 - 2.1e-75 252.6 0.0 2.9e-74 248.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EMR64427.1 - 2.6e-23 82.3 1.1 1.5e-22 79.9 0.3 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EMR64427.1 - 7.7e-12 44.9 0.0 1.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EMR64427.1 - 6.9e-09 35.8 2.4 4.4e-07 30.1 1.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMR64427.1 - 1.7e-08 34.5 2.4 1.7e-08 34.5 2.4 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 EMR64427.1 - 1.2e-05 25.4 1.8 0.054 13.5 0.4 2.9 1 1 1 2 2 2 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 EMR64427.1 - 0.00024 21.4 0.6 0.0053 17.1 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF4674 PF15719.5 EMR64427.1 - 0.0063 16.6 4.4 0.013 15.6 4.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4674) GRP PF07172.11 EMR64427.1 - 0.013 16.2 1.5 0.013 16.2 1.5 1.8 2 0 0 2 2 2 0 Glycine rich protein family zf-DBF PF07535.12 EMR64427.1 - 0.021 14.9 1.0 0.021 14.9 1.0 2.3 2 1 0 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.6 EMR64427.1 - 0.21 12.5 1.0 17 6.6 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PLU-1 PF08429.11 EMR64428.1 - 3.8e-115 384.7 14.6 4.3e-112 374.6 14.5 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EMR64428.1 - 3.5e-43 146.6 0.5 8.5e-43 145.4 0.5 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 EMR64428.1 - 1.2e-13 51.2 7.9 2.6e-13 50.1 7.9 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.29 EMR64428.1 - 1e-07 31.7 8.6 1e-07 31.7 8.6 4.1 3 1 0 3 3 3 1 PHD-finger Nexin_C PF08628.12 EMR64428.1 - 0.071 13.7 0.5 0.26 11.9 0.5 1.9 1 0 0 1 1 1 0 Sorting nexin C terminal Amino_oxidase PF01593.24 EMR64429.1 - 2e-29 103.2 0.3 2.4e-29 102.9 0.3 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Gln-synt_C-ter PF18318.1 EMR64429.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase C-terminal domain SGT1 PF07093.11 EMR64431.1 - 0.83 8.0 14.8 0.7 8.3 8.3 2.1 2 0 0 2 2 2 0 SGT1 protein Fungal_trans PF04082.18 EMR64433.1 - 4.4e-15 55.4 1.1 4.4e-15 55.4 1.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR64433.1 - 4.7e-08 33.0 9.6 9.4e-08 32.1 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_3 PF13606.6 EMR64435.1 - 9e-06 25.7 1.3 0.1 13.2 0.0 5.9 4 2 2 6 6 6 1 Ankyrin repeat Ank_2 PF12796.7 EMR64435.1 - 8.1e-05 23.1 0.0 0.093 13.3 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) F-box-like PF12937.7 EMR64435.1 - 0.00015 21.5 0.0 0.00042 20.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like Ank_4 PF13637.6 EMR64435.1 - 0.004 17.7 0.1 0.35 11.5 0.0 4.0 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 EMR64435.1 - 0.025 15.0 0.2 9.6 6.9 0.1 4.0 5 1 0 5 5 5 0 Ankyrin repeat TauD PF02668.16 EMR64437.1 - 1.2e-40 140.0 0.1 1.8e-40 139.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EMR64437.1 - 8.9e-08 32.7 0.0 2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EMR64437.1 - 0.0017 17.6 0.0 0.0025 17.0 0.0 1.3 1 1 0 1 1 1 1 CsiD ADH_zinc_N PF00107.26 EMR64438.1 - 2.7e-07 30.6 0.0 5.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_synthase PF02540.17 EMR64438.1 - 0.004 16.3 0.1 2.1 7.4 0.1 2.1 2 0 0 2 2 2 2 NAD synthase ADH_zinc_N_2 PF13602.6 EMR64438.1 - 0.028 15.5 0.0 0.056 14.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IBR PF01485.21 EMR64439.1 - 1e-11 44.9 39.9 1.6e-07 31.4 4.0 4.0 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EMR64439.1 - 0.0004 20.2 6.6 0.0004 20.2 6.6 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR64439.1 - 0.0017 18.2 5.6 0.0017 18.2 5.6 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR64439.1 - 0.0021 18.1 5.9 0.0021 18.1 5.9 3.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EMR64439.1 - 0.0026 18.1 7.1 0.0026 18.1 7.1 4.2 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 EMR64439.1 - 0.006 16.7 7.2 0.006 16.7 7.2 3.6 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMR64439.1 - 0.012 15.6 8.2 0.012 15.6 8.2 3.4 3 0 0 3 3 3 0 zinc-RING finger domain RRM_1 PF00076.22 EMR64439.1 - 0.027 14.3 0.0 0.69 9.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLS PF14611.6 EMR64439.1 - 0.092 12.6 0.2 1.2 9.0 0.0 2.6 2 1 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator zf-RING_14 PF17978.1 EMR64439.1 - 5.1 7.6 12.3 0.034 14.6 2.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_115 PF15979.5 EMR64440.1 - 1.1e-123 413.0 0.1 1.9e-123 412.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EMR64440.1 - 2.6e-39 134.8 0.0 4.4e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain RcsC PF09456.10 EMR64440.1 - 0.098 12.7 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) MFS_1 PF07690.16 EMR64441.1 - 3.7e-26 91.9 25.2 1.2e-24 86.9 25.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EMR64442.1 - 3e-13 49.3 0.3 2.3e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR64442.1 - 6.8e-05 22.9 10.1 6.8e-05 22.9 10.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 EMR64442.1 - 0.33 11.3 5.4 0.58 10.5 5.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Utp13 PF08625.11 EMR64443.1 - 3.9e-52 175.9 0.8 5.5e-52 175.5 0.8 1.2 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 EMR64443.1 - 1.4e-24 85.9 10.6 5.9e-05 23.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR64443.1 - 0.0021 18.3 0.1 29 5.1 0.0 4.2 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EMR64443.1 - 0.0096 14.7 0.4 3.5 6.3 0.0 3.0 3 0 0 3 3 3 2 Nup133 N terminal like Sulfotransfer_4 PF17784.1 EMR64443.1 - 0.089 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Sulfotransferase domain GPI-anchored PF10342.9 EMR64443.1 - 1.5 9.6 3.6 30 5.5 0.2 2.5 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dehydratase_hem PF13816.6 EMR64444.1 - 1.3e-114 382.8 0.0 1.5e-114 382.6 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 EMR64444.1 - 0.00083 19.7 0.0 0.84 10.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) AA_permease_2 PF13520.6 EMR64445.1 - 1.6e-49 168.9 57.6 2e-49 168.6 57.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR64445.1 - 5e-29 101.2 52.7 6.4e-29 100.9 52.7 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 EMR64445.1 - 0.1 12.5 0.4 0.23 11.3 0.4 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) MBOAT_2 PF13813.6 EMR64446.1 - 1.3e-15 57.4 3.1 3.1e-15 56.2 3.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4131 PF13567.6 EMR64446.1 - 0.02 14.6 0.2 0.02 14.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CTP_transf_1 PF01148.20 EMR64446.1 - 0.047 13.4 1.6 0.058 13.2 0.5 1.7 2 0 0 2 2 2 0 Cytidylyltransferase family XPG_I PF00867.18 EMR64447.1 - 2.1e-18 66.4 0.0 3.5e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EMR64447.1 - 0.00067 20.1 0.0 0.0029 18.1 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EMR64447.1 - 0.038 13.5 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing CopD PF05425.13 EMR64448.1 - 0.012 15.9 1.5 0.017 15.5 0.5 1.7 1 1 1 2 2 2 0 Copper resistance protein D DUF5336 PF17270.2 EMR64448.1 - 0.2 11.3 2.2 0.27 10.8 2.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Lipase_GDSL_2 PF13472.6 EMR64449.1 - 4.5e-11 43.5 0.1 5.4e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR64449.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 EMR64450.1 - 3.1e-14 52.7 16.1 3.1e-14 52.7 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EMR64450.1 - 0.00036 20.3 0.9 0.00036 20.3 0.9 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Chol_subst-bind PF09129.11 EMR64450.1 - 0.087 11.8 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding BORCS6 PF10157.9 EMR64451.1 - 0.00016 21.9 0.1 0.0002 21.6 0.1 1.3 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 DUF327 PF03885.13 EMR64451.1 - 0.0045 17.0 2.3 0.46 10.4 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF327) Not3 PF04065.15 EMR64451.1 - 0.005 16.3 2.6 0.0074 15.8 2.5 1.4 1 1 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component APC1_C PF18122.1 EMR64451.1 - 0.071 13.1 1.1 0.1 12.5 1.0 1.3 1 1 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF4164 PF13747.6 EMR64451.1 - 0.08 13.2 4.7 4.3 7.7 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 EMR64451.1 - 0.14 12.2 2.6 0.4 10.7 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EMR64451.1 - 0.17 12.1 4.0 0.28 11.3 4.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Retrotrans_gag PF03732.17 EMR64451.1 - 0.28 11.5 2.1 0.91 9.8 0.1 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein FUSC PF04632.12 EMR64451.1 - 4.1 5.8 9.2 5 5.5 9.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSBP1 PF06825.12 EMR64451.1 - 4.6 7.2 7.4 7.7 6.5 2.1 3.0 2 1 1 3 3 3 0 Heat shock factor binding protein 1 CCDC-167 PF15188.6 EMR64451.1 - 5 7.5 7.4 0.98 9.8 1.6 2.6 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 PspB PF06667.12 EMR64451.1 - 6.9 6.8 7.1 1.6 8.8 0.5 2.5 2 1 1 3 3 3 0 Phage shock protein B Lipase_GDSL_2 PF13472.6 EMR64452.1 - 1.4e-12 48.4 0.2 2.8e-12 47.4 0.2 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR64452.1 - 4.7e-08 33.3 0.6 1.4e-07 31.7 0.6 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 EMR64452.1 - 0.13 12.3 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Lebercilin PF15619.6 EMR64453.1 - 0.0017 18.1 11.9 0.03 14.0 1.8 2.1 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.19 EMR64453.1 - 0.027 14.3 9.8 0.036 13.9 9.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.8 EMR64453.1 - 0.029 14.5 7.8 0.048 13.8 7.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EMR64453.1 - 0.032 13.1 10.5 0.04 12.8 10.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Med4 PF10018.9 EMR64453.1 - 0.042 13.5 3.4 1.3 8.7 0.3 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 HrpB7 PF09486.10 EMR64453.1 - 0.055 13.8 4.3 0.08 13.3 4.3 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FAM76 PF16046.5 EMR64453.1 - 0.1 11.9 6.6 2.2 7.5 0.2 2.1 1 1 1 2 2 2 0 FAM76 protein FAM184 PF15665.5 EMR64453.1 - 0.28 10.9 8.4 0.39 10.5 8.4 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EMR64453.1 - 0.32 11.4 0.1 0.32 11.4 0.1 3.2 2 1 1 3 3 3 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 EMR64453.1 - 0.37 10.7 19.6 0.37 10.7 2.0 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase APG6_N PF17675.1 EMR64453.1 - 0.52 10.8 13.0 0.71 10.4 13.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 EMR64453.1 - 0.64 10.2 13.4 7.1 6.8 13.2 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 EMR64453.1 - 2 9.0 12.0 20 5.8 5.3 2.7 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C4H2 PF10146.9 EMR64453.1 - 2.5 8.3 5.3 4.3 7.6 5.3 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein AKAP7_NLS PF10469.9 EMR64455.1 - 1.8e-26 93.3 0.0 3e-26 92.6 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EMR64455.1 - 0.003 17.5 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily FHA PF00498.26 EMR64456.1 - 6.7e-16 58.4 0.0 1.1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EMR64456.1 - 0.0006 20.1 0.0 0.029 14.7 0.0 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain HAD_SAK_1 PF10307.9 EMR64457.1 - 7.9e-78 260.9 0.0 1.5e-77 260.0 0.0 1.5 2 0 0 2 2 2 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Glyco_hydro_18 PF00704.28 EMR64458.1 - 2.6e-60 204.8 0.0 7.6e-60 203.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Tim17 PF02466.19 EMR64459.1 - 4.1e-07 30.4 8.0 5e-07 30.1 7.2 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ycf66_N PF07444.11 EMR64459.1 - 0.039 14.1 0.6 0.079 13.1 0.1 1.7 2 0 0 2 2 2 0 Ycf66 protein N-terminus adh_short PF00106.25 EMR64462.1 - 6.2e-32 110.6 0.0 1.9e-31 109.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64462.1 - 2.3e-24 86.3 0.0 3.5e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64462.1 - 4.9e-08 33.1 0.2 3.7e-07 30.2 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMR64462.1 - 1.1e-06 28.3 0.1 2.2e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR64462.1 - 3.6e-05 23.7 0.3 5.1e-05 23.3 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR64462.1 - 0.00024 20.6 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMR64462.1 - 0.0022 17.6 0.3 0.0037 16.9 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 EMR64462.1 - 0.023 14.8 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EMR64462.1 - 0.035 14.4 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 EMR64462.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Transferase PF02458.15 EMR64464.1 - 1.1e-07 31.0 0.0 0.0043 15.7 0.0 2.3 2 0 0 2 2 2 2 Transferase family DUF167 PF02594.16 EMR64465.1 - 1e-22 80.0 0.1 1.7e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 ADH_zinc_N PF00107.26 EMR64466.1 - 6.3e-28 97.3 0.1 1.1e-27 96.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR64466.1 - 4.4e-21 76.3 0.0 8e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR64466.1 - 2.7e-08 33.6 0.0 7.2e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EMR64466.1 - 0.049 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Peptidase_C15 PF01470.17 EMR64468.1 - 6.3e-14 52.6 0.0 4.7e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase DNA_primase_S PF01896.19 EMR64469.1 - 6.3e-62 208.7 0.1 9.4e-62 208.2 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit UCH PF00443.29 EMR64470.1 - 1.2e-34 120.0 0.0 3.6e-34 118.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMR64470.1 - 9.4e-07 28.7 1.2 0.014 15.0 0.1 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 EMR64470.1 - 0.00063 19.6 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 PUB domain Josephin PF02099.17 EMR64470.1 - 0.11 12.5 0.2 0.63 10.1 0.1 2.2 2 0 0 2 2 2 0 Josephin Flavin_Reduct PF01613.18 EMR64471.1 - 3e-17 63.1 2.2 3e-15 56.6 0.1 2.5 2 1 0 2 2 2 2 Flavin reductase like domain Ribosomal_L31 PF01197.18 EMR64472.1 - 0.037 14.2 0.5 0.061 13.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L31 Flavodoxin_1 PF00258.25 EMR64473.1 - 1e-23 84.1 0.0 3.2e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 EMR64473.1 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_5 PF12724.7 EMR64473.1 - 0.00062 20.0 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain p450 PF00067.22 EMR64473.1 - 0.011 14.5 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 0 Cytochrome P450 Pyr_redox_2 PF07992.14 EMR64474.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EMR64475.1 - 5e-43 147.4 0.0 5.7e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64475.1 - 9.7e-26 90.6 0.0 1.3e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR64475.1 - 0.019 13.8 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EMR64475.1 - 0.23 10.4 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RRG8 PF17068.5 EMR64476.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial AIF-MLS PF14962.6 EMR64476.1 - 1.2 9.0 10.7 2.3 8.2 10.7 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Med11 PF10280.9 EMR64477.1 - 4e-40 137.4 0.0 4.8e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein FAD_binding_3 PF01494.19 EMR64479.1 - 2.8e-26 92.6 0.0 5.8e-26 91.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR64479.1 - 4.4e-08 33.1 0.3 6e-05 22.8 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR64479.1 - 3.2e-06 26.6 0.0 0.00011 21.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR64479.1 - 5.2e-06 26.6 0.1 1.5e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMR64479.1 - 9e-05 23.0 0.4 0.0056 17.2 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR64479.1 - 0.00015 21.1 0.0 0.0068 15.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR64479.1 - 0.00047 19.3 0.0 0.00093 18.3 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR64479.1 - 0.0015 17.7 0.2 0.003 16.7 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 EMR64479.1 - 0.0039 16.1 0.1 0.11 11.3 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 EMR64479.1 - 0.0067 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EMR64479.1 - 0.0076 15.6 0.0 0.047 13.0 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR64479.1 - 0.011 14.4 0.0 0.19 10.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 EMR64479.1 - 0.016 14.5 0.0 0.074 12.3 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SE PF08491.10 EMR64479.1 - 0.016 14.2 0.0 0.063 12.3 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 EMR64479.1 - 0.054 12.6 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EMR64479.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CLP_protease PF00574.23 EMR64480.1 - 3.3e-65 219.4 0.1 1.1e-64 217.6 0.1 1.7 1 1 0 1 1 1 1 Clp protease SDH_sah PF01972.16 EMR64480.1 - 0.013 14.5 0.2 0.024 13.7 0.1 1.5 1 1 1 2 2 2 0 Serine dehydrogenase proteinase UDPGT PF00201.18 EMR64481.1 - 0.00023 20.1 0.0 0.00034 19.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase RCDG1 PF15725.5 EMR64481.1 - 0.15 12.5 5.9 0.43 11.0 5.9 1.7 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Vps5 PF09325.10 EMR64482.1 - 6.9e-88 294.2 6.3 1.1e-87 293.5 6.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EMR64482.1 - 7.9e-25 87.0 0.1 1.7e-24 85.9 0.1 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.9 EMR64482.1 - 0.00091 18.4 1.8 0.0039 16.4 2.1 1.8 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EMR64482.1 - 0.0026 17.5 6.0 0.0048 16.6 6.0 1.4 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.9 EMR64482.1 - 0.0037 16.7 1.1 0.061 12.8 1.1 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_3 PF16746.5 EMR64482.1 - 0.0052 16.5 7.4 0.011 15.5 2.8 2.5 1 1 1 2 2 2 1 BAR domain of APPL family HBM PF16591.5 EMR64482.1 - 0.32 10.4 9.8 4.5 6.6 6.0 2.7 1 1 1 2 2 2 0 Helical bimodular sensor domain DUF713 PF05218.14 EMR64482.1 - 0.34 10.6 5.4 0.24 11.1 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF713) AcylCoA_dehyd_C PF12186.8 EMR64482.1 - 0.75 9.9 3.6 0.79 9.9 0.9 2.2 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase C terminal FadA PF09403.10 EMR64482.1 - 9.1 6.8 7.9 3.7 8.1 0.0 3.6 4 0 0 4 4 4 0 Adhesion protein FadA KR PF08659.10 EMR64483.1 - 5.8e-59 199.0 3.6 2.5e-58 196.9 0.1 2.8 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EMR64483.1 - 3.1e-28 98.9 0.0 5.2e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EMR64483.1 - 1.5e-21 77.0 0.0 2.4e-20 73.1 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EMR64483.1 - 1.8e-20 74.3 0.0 1.2e-17 65.2 0.0 3.3 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR64483.1 - 2.8e-15 56.5 0.1 3.6e-14 52.8 0.1 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EMR64483.1 - 2.9e-15 56.5 0.0 6.5e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR64483.1 - 3.8e-12 46.8 0.0 1.6e-10 41.6 0.0 3.4 4 0 0 4 4 3 1 Methyltransferase domain adh_short PF00106.25 EMR64483.1 - 2.5e-10 40.1 0.9 1e-08 34.9 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_11 PF08241.12 EMR64483.1 - 2.5e-09 37.7 0.0 5.4e-08 33.4 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain adh_short_C2 PF13561.6 EMR64483.1 - 1.6e-07 31.1 0.7 1.6e-05 24.6 0.0 3.2 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 EMR64483.1 - 1.5e-06 27.8 0.0 4.9e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 EMR64483.1 - 3.1e-06 27.5 0.2 1.6e-05 25.2 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EMR64483.1 - 5.5e-06 26.3 0.0 1.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PALP PF00291.25 EMR64483.1 - 0.24 10.8 3.0 1 8.7 0.7 2.6 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme WD40 PF00400.32 EMR64484.1 - 3.1e-40 135.4 30.6 5.2e-09 36.6 3.3 7.0 7 1 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EMR64484.1 - 3.9e-40 137.1 0.0 5.6e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EMR64484.1 - 2.3e-14 53.5 0.7 0.026 14.8 0.0 5.5 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EMR64484.1 - 2.3e-06 27.4 0.0 4.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 EMR64484.1 - 0.00015 21.7 0.0 0.0041 17.0 0.0 2.7 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 EMR64484.1 - 0.0052 16.1 0.0 1.2 8.3 0.0 2.8 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 EMR64484.1 - 0.0053 15.5 1.0 4.9 5.7 0.1 3.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EMR64484.1 - 0.45 9.4 2.2 1.7 7.5 0.8 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Orbi_VP6 PF01516.16 EMR64484.1 - 1.2 8.6 10.1 2.3 7.7 10.1 1.4 1 0 0 1 1 1 0 Orbivirus helicase VP6 HSP90 PF00183.18 EMR64485.1 - 3.3e-223 742.3 29.2 4e-223 742.0 29.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EMR64485.1 - 3.1e-15 56.7 0.0 6e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMR64485.1 - 3.4e-10 39.9 0.1 3.4e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serglycin PF04360.12 EMR64486.1 - 0.28 11.1 1.2 0.66 9.9 1.2 1.6 1 0 0 1 1 1 0 Serglycin FMO-like PF00743.19 EMR64487.1 - 0.0075 14.7 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Lipase_3 PF01764.25 EMR64488.1 - 6e-34 117.0 0.0 9.4e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 EMR64488.1 - 1.5e-05 24.9 0.5 3.6e-05 23.7 0.5 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF676 PF05057.14 EMR64488.1 - 3.6e-05 23.4 0.0 5.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EMR64488.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR64488.1 - 0.025 15.2 0.4 0.044 14.4 0.4 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Msg2_C PF12373.8 EMR64488.1 - 0.085 12.3 3.3 0.21 11.0 0.4 2.6 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal ASL_C2 PF14698.6 EMR64488.1 - 0.16 12.7 0.5 1.1 10.1 0.1 2.3 2 0 0 2 2 2 0 Argininosuccinate lyase C-terminal DUF4743 PF15916.5 EMR64489.1 - 2.1e-11 43.9 0.0 3.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EMR64489.1 - 3.6e-09 36.8 0.1 6.8e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_1 PF00561.20 EMR64490.1 - 4.4e-16 59.3 0.2 7.6e-16 58.5 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR64490.1 - 1.9e-14 54.8 4.2 2.7e-14 54.3 4.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR64490.1 - 3e-05 23.4 0.0 6.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Glyco_hydro_43 PF04616.14 EMR64491.1 - 1.2e-26 93.7 0.7 1.5e-26 93.4 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Rad52_Rad22 PF04098.15 EMR64492.1 - 3.9e-61 205.5 0.0 4.6e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Filament PF00038.21 EMR64493.1 - 6.3e-06 26.0 21.9 6.3e-06 26.0 21.9 3.8 2 1 0 3 3 3 2 Intermediate filament protein Lzipper-MIP1 PF14389.6 EMR64493.1 - 0.017 15.4 19.4 0.091 13.1 2.8 4.9 4 2 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 EMR64493.1 - 0.5 10.7 0.0 0.5 10.7 0.0 5.4 6 1 0 6 6 6 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 EMR64493.1 - 5.8 6.9 14.6 6.7 6.7 0.1 5.4 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region Lipase_GDSL_2 PF13472.6 EMR64494.1 - 1.6e-12 48.2 2.4 1.9e-12 47.9 2.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR64494.1 - 3.8e-05 23.7 0.3 6.1e-05 23.1 0.3 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 EMR64494.1 - 0.025 14.3 0.2 0.066 12.9 0.1 1.7 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX Pkinase PF00069.25 EMR64495.1 - 5e-64 216.2 0.0 6.4e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64495.1 - 1.2e-38 132.9 0.0 1.6e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR64495.1 - 0.00029 19.8 0.0 0.00046 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMR64495.1 - 0.00055 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EMR64495.1 - 0.017 14.1 0.1 0.025 13.6 0.1 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EMR64495.1 - 0.048 12.7 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 EMR64495.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase HAD_2 PF13419.6 EMR64496.1 - 2.3e-09 37.6 0.0 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR64496.1 - 4.2e-09 37.0 0.3 0.00071 19.9 0.5 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR64496.1 - 2.4e-06 27.5 1.7 4.9e-06 26.5 1.6 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EMR64496.1 - 0.022 15.2 1.2 0.3 11.5 1.2 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5523 PF17661.1 EMR64496.1 - 0.23 11.1 2.7 0.36 10.5 2.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF5321 PF17254.2 EMR64496.1 - 4.9 6.6 6.9 8.3 5.8 6.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5321) Cu-oxidase_2 PF07731.14 EMR64497.1 - 8.2e-40 135.7 7.9 1.2e-36 125.5 0.5 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMR64497.1 - 3.2e-36 123.9 7.2 5.4e-35 120.0 0.1 3.7 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EMR64497.1 - 3.3e-28 98.8 1.3 2.8e-25 89.3 0.1 2.8 2 1 1 3 3 3 2 Multicopper oxidase ketoacyl-synt PF00109.26 EMR64499.1 - 3.3e-50 171.0 0.1 6.1e-50 170.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EMR64499.1 - 5.7e-44 150.9 0.0 1.2e-43 149.8 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR64499.1 - 5.5e-37 126.4 0.6 1.5e-36 125.0 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EMR64499.1 - 1.4e-24 87.5 0.0 1.7e-23 84.0 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EMR64499.1 - 4.2e-22 78.3 2.2 2e-11 44.1 0.1 2.5 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 EMR64499.1 - 2e-10 40.4 0.0 3.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EMR64499.1 - 1.8e-06 27.5 0.3 0.0002 20.8 0.1 3.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 EMR64499.1 - 5.1e-05 24.0 1.3 0.0042 17.7 0.1 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 EMR64499.1 - 0.00035 21.0 0.0 0.0009 19.7 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 EMR64499.1 - 0.0014 18.0 0.1 0.046 13.0 0.0 2.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 EMR64499.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SH2_2 PF14633.6 EMR64500.1 - 1.4e-86 289.3 0.0 1.4e-86 289.3 0.0 2.0 2 0 0 2 2 2 1 SH2 domain HTH_44 PF14641.6 EMR64500.1 - 9.9e-39 132.3 0.7 3.1e-38 130.7 0.7 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EMR64500.1 - 2.7e-31 108.0 0.0 5.5e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EMR64500.1 - 2e-29 102.3 0.0 8e-29 100.4 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EMR64500.1 - 2.8e-19 69.5 31.0 2.8e-19 69.5 31.0 6.4 4 2 1 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 EMR64500.1 - 1.8e-07 32.0 1.5 5.2e-06 27.3 1.5 3.5 2 1 0 2 2 2 1 HHH domain S1 PF00575.23 EMR64500.1 - 3.5e-06 27.3 0.5 9.8e-06 25.8 0.5 1.9 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 EMR64500.1 - 5.8e-06 26.3 0.0 2.4e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 SH2 domain HHH_3 PF12836.7 EMR64500.1 - 0.00039 20.6 0.0 0.0018 18.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif adh_short_C2 PF13561.6 EMR64501.1 - 7.7e-20 71.5 0.0 1.5e-19 70.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR64501.1 - 2.9e-11 43.2 0.0 3.8e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Oxysterol_BP PF01237.18 EMR64502.1 - 5.6e-107 357.8 0.0 6.3e-107 357.6 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PAP1 PF08601.10 EMR64503.1 - 2.6e-63 215.0 15.0 2e-59 202.2 4.8 4.0 2 2 1 4 4 4 2 Transcription factor PAP1 bZIP_1 PF00170.21 EMR64503.1 - 2.3e-09 37.2 13.7 4.6e-09 36.2 13.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 EMR64503.1 - 0.00018 21.4 0.6 0.00036 20.4 0.6 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family SHE3 PF17078.5 EMR64503.1 - 0.00025 20.9 6.4 0.00054 19.7 6.4 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 IFP_35_N PF07334.13 EMR64503.1 - 0.0032 17.5 0.6 0.009 16.1 0.3 1.9 1 1 0 1 1 1 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus Fmp27_WPPW PF10359.9 EMR64503.1 - 0.0035 16.2 0.1 0.0035 16.2 0.1 1.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Cnn_1N PF07989.11 EMR64503.1 - 0.0071 16.5 5.3 0.019 15.1 5.3 1.7 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 DUF812 PF05667.11 EMR64503.1 - 0.0089 15.0 2.8 0.012 14.5 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF5082 PF16888.5 EMR64503.1 - 0.011 16.1 3.0 0.024 14.9 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) dsrm PF00035.26 EMR64503.1 - 0.013 16.2 0.4 0.23 12.2 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif TolA_bind_tri PF16331.5 EMR64503.1 - 0.017 15.2 1.4 0.035 14.2 1.4 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation bZIP_2 PF07716.15 EMR64503.1 - 0.023 14.8 15.4 0.14 12.2 15.4 2.2 1 1 0 1 1 1 0 Basic region leucine zipper DUF16 PF01519.16 EMR64503.1 - 0.026 15.0 2.6 0.027 15.0 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 Cluap1 PF10234.9 EMR64503.1 - 0.029 13.8 5.2 0.045 13.1 5.2 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 KLRAQ PF10205.9 EMR64503.1 - 0.034 14.4 4.0 0.11 12.7 4.0 1.9 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein SlyX PF04102.12 EMR64503.1 - 0.038 14.6 0.4 0.092 13.4 0.4 1.7 1 0 0 1 1 1 0 SlyX APG6_N PF17675.1 EMR64503.1 - 0.072 13.6 5.9 0.14 12.7 5.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Lebercilin PF15619.6 EMR64503.1 - 0.081 12.6 9.0 0.13 11.9 9.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_Maf PF03131.17 EMR64503.1 - 0.084 13.4 9.3 0.16 12.5 9.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.11 EMR64503.1 - 0.11 12.9 2.6 0.22 12.0 2.6 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 EMR64503.1 - 0.17 12.3 4.3 0.32 11.4 4.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 EMR64503.1 - 0.2 11.4 3.9 0.37 10.6 3.9 1.5 1 0 0 1 1 1 0 Septum formation initiator TMCO5 PF14992.6 EMR64503.1 - 0.5 9.9 4.9 0.87 9.1 4.9 1.3 1 0 0 1 1 1 0 TMCO5 family UPF0242 PF06785.11 EMR64503.1 - 0.52 10.4 5.9 1 9.4 5.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin PF02996.17 EMR64503.1 - 0.54 10.2 4.1 0.98 9.4 4.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit Prefoldin_2 PF01920.20 EMR64503.1 - 0.58 10.1 7.9 1.1 9.2 7.9 1.4 1 0 0 1 1 1 0 Prefoldin subunit RE_SacI PF09566.10 EMR64503.1 - 0.69 9.7 3.2 0.56 10.0 0.6 1.9 2 0 0 2 2 2 0 SacI restriction endonuclease DUF1664 PF07889.12 EMR64503.1 - 0.74 9.9 2.1 0.86 9.6 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 EMR64503.1 - 0.81 10.2 7.5 0.67 10.4 6.0 1.6 1 1 0 1 1 1 0 Cell division protein ZapB TMPIT PF07851.13 EMR64503.1 - 1.7 7.8 3.0 3.1 6.9 3.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein CDC45 PF02724.14 EMR64503.1 - 4.5 5.4 12.1 6.3 5.0 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein XhlA PF10779.9 EMR64503.1 - 8.6 6.6 5.4 18 5.7 5.4 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Glyco_hydro_31 PF01055.26 EMR64505.1 - 1.1e-105 354.4 0.1 1.3e-105 354.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EMR64505.1 - 1.5e-14 54.0 0.4 5.1e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Ceramidase_alk PF04734.13 EMR64506.1 - 4.3e-200 665.7 0.2 3.4e-198 659.4 0.2 2.0 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EMR64506.1 - 7.1e-63 211.5 0.1 1.1e-62 210.8 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Apidaecin PF00807.17 EMR64506.1 - 0.19 11.8 0.1 0.51 10.5 0.1 1.7 1 0 0 1 1 1 0 Apidaecin Utp14 PF04615.13 EMR64507.1 - 2.6e-187 624.8 70.7 2.6e-187 624.8 70.7 2.5 1 1 1 2 2 2 1 Utp14 protein Glucosamine_iso PF01182.20 EMR64508.1 - 2.4e-14 53.7 0.0 4.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pyr_redox_2 PF07992.14 EMR64510.1 - 5.8e-47 160.3 0.5 8.5e-47 159.8 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EMR64510.1 - 5.5e-18 65.0 0.0 1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 EMR64510.1 - 4e-17 62.6 3.6 9.9e-15 54.9 0.9 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 EMR64510.1 - 3.3e-15 56.2 7.0 1.2e-12 47.9 5.2 3.4 2 1 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 EMR64510.1 - 5.8e-12 45.5 0.0 4.1e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain Rieske PF00355.26 EMR64510.1 - 5.3e-11 42.3 0.1 1.2e-05 25.2 0.0 2.9 3 0 0 3 3 3 2 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 EMR64510.1 - 2.3e-09 37.0 0.0 4.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 EMR64510.1 - 3.4e-05 23.7 0.0 1.1 9.3 0.0 4.0 4 0 0 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 EMR64510.1 - 0.00028 20.9 1.0 3.6 7.5 0.1 3.8 2 2 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMR64510.1 - 0.00054 19.3 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR64510.1 - 0.2 10.7 0.0 0.6 9.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EMR64510.1 - 0.21 10.9 1.1 9.5 5.4 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Hexokinase_2 PF03727.16 EMR64511.1 - 1.6e-55 188.2 0.0 4.9e-55 186.6 0.0 1.7 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EMR64511.1 - 6.7e-42 143.7 0.0 1.1e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase RskA PF10099.9 EMR64511.1 - 0.017 15.5 1.5 0.017 15.5 1.5 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MYO10_CC PF16735.5 EMR64511.1 - 0.18 11.9 1.2 0.4 10.8 1.2 1.6 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain Abhydrolase_3 PF07859.13 EMR64512.1 - 1.7e-40 139.1 0.0 3.5e-31 108.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMR64512.1 - 4.1e-16 58.8 0.0 9.4e-16 57.6 0.0 1.5 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 EMR64512.1 - 0.0011 17.9 0.2 0.022 13.7 0.2 2.2 1 1 0 1 1 1 1 Carboxylesterase family BSD PF03909.17 EMR64513.1 - 1.3e-18 66.7 0.1 3.1e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 BSD domain POTRA_TamA_1 PF17243.2 EMR64513.1 - 0.081 13.0 0.5 22 5.3 0.2 2.8 2 0 0 2 2 2 0 POTRA domain TamA domain 1 Suf PF05843.14 EMR64513.1 - 0.14 12.1 8.5 0.024 14.6 2.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2076 PF09849.9 EMR64514.1 - 0.36 10.8 1.5 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) HTH_23 PF13384.6 EMR64515.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 EMR64515.1 - 0.079 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase WGG PF10273.9 EMR64516.1 - 1.6e-31 108.8 0.1 2.5e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 KfrA_N PF11740.8 EMR64516.1 - 0.018 15.7 0.0 0.035 14.8 0.0 1.5 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term CENP-B_dimeris PF09026.10 EMR64516.1 - 2.3 8.6 7.0 5.4 7.5 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_hydro_3_C PF01915.22 EMR64517.1 - 2.3e-50 171.4 0.1 4.3e-50 170.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR64517.1 - 1.4e-47 162.6 0.0 1.7e-28 100.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR64517.1 - 2.7e-22 78.6 1.5 3.1e-22 78.5 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain ToxS PF17323.2 EMR64517.1 - 0.005 16.5 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 Trans-membrane regulatory protein ToxS DUF11 PF01345.18 EMR64517.1 - 0.072 13.4 0.5 0.55 10.6 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF11 Sugar-bind PF04198.13 EMR64517.1 - 0.099 11.8 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Putative sugar-binding domain Pkinase PF00069.25 EMR64518.1 - 1.8e-59 201.3 0.0 2.3e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64518.1 - 8.2e-31 107.2 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR64518.1 - 0.00067 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMR64518.1 - 0.0081 16.1 1.7 0.023 14.6 0.2 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EMR64518.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMR64518.1 - 0.03 13.1 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pex14_N PF04695.13 EMR64518.1 - 0.3 11.7 7.5 0.5 11.0 7.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tubulin PF00091.25 EMR64519.1 - 5.7e-69 232.3 0.0 1.4e-68 231.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMR64519.1 - 5.9e-43 146.0 0.1 9.7e-43 145.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EMR64519.1 - 3.9e-05 23.9 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EMR64519.1 - 0.0023 17.2 0.0 0.024 13.8 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EMR64519.1 - 0.0032 17.2 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF1604 PF07713.13 EMR64520.1 - 4.9e-38 128.8 6.0 4.9e-38 128.8 6.0 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EMR64520.1 - 1.5e-06 28.0 2.7 1.5e-06 28.0 2.7 2.6 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 EMR64520.1 - 0.013 15.5 0.2 0.013 15.5 0.2 3.9 4 1 0 4 4 4 0 G-patch domain Ank_2 PF12796.7 EMR64521.1 - 1.4e-16 60.8 0.5 0.00036 21.1 0.0 4.3 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR64521.1 - 6.5e-16 58.5 1.3 0.00014 22.3 0.0 4.4 4 2 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR64521.1 - 3.1e-15 54.8 2.0 0.0011 19.2 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EMR64521.1 - 2.6e-13 49.7 8.0 0.0027 18.1 0.1 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EMR64521.1 - 3.4e-08 33.6 2.0 0.03 14.7 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.7 EMR64521.1 - 1.6e-05 24.7 0.0 5.9e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like Asparaginase_II PF06089.12 EMR64522.1 - 1.5e-121 405.4 1.3 1.7e-121 405.2 1.3 1.0 1 0 0 1 1 1 1 L-asparaginase II MRP-L27 PF09809.9 EMR64523.1 - 1.2e-17 63.7 0.4 1.9e-17 63.1 0.4 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 B12D PF06522.11 EMR64524.1 - 0.0027 17.5 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Glyco_hydro_10 PF00331.20 EMR64525.1 - 1.6e-97 326.5 0.0 1.8e-97 326.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 FAR1 PF03101.15 EMR64526.1 - 5.8e-06 26.9 0.5 9e-06 26.3 0.5 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 EMR64526.1 - 0.01 16.2 0.2 0.015 15.7 0.2 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sugarporin_N PF11471.8 EMR64526.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension WASH_WAHD PF11945.8 EMR64526.1 - 0.21 11.1 0.0 0.31 10.5 0.0 1.1 1 0 0 1 1 1 0 WAHD domain of WASH complex OmpH PF03938.14 EMR64526.1 - 0.25 11.7 0.0 15 5.9 0.0 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) MFS_1 PF07690.16 EMR64527.1 - 3.2e-45 154.6 58.2 6.2e-43 147.1 56.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Arrestin_C PF02752.22 EMR64528.1 - 1.3e-07 32.1 0.0 1.2e-06 29.0 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EMR64528.1 - 0.0079 16.3 0.1 0.081 13.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rhomboid PF01694.22 EMR64529.1 - 1.4e-34 119.2 10.0 1.4e-34 119.2 10.0 2.5 3 0 0 3 3 3 1 Rhomboid family Wzy_C PF04932.15 EMR64529.1 - 0.21 11.2 4.2 2.7 7.6 0.3 2.6 2 0 0 2 2 2 0 O-Antigen ligase SnoaL_4 PF13577.6 EMR64530.1 - 6.1e-09 36.1 0.0 1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Cnd3 PF12719.7 EMR64531.1 - 2.5e-89 299.4 0.0 8.5e-89 297.6 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EMR64531.1 - 3e-08 33.9 15.0 1.5e-05 25.3 1.1 5.2 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 EMR64531.1 - 1.1e-06 28.4 10.0 0.14 12.5 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 EMR64531.1 - 0.076 11.6 0.1 0.68 8.4 0.0 2.4 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 EMR64531.1 - 0.082 12.9 8.6 0.25 11.4 0.1 4.8 4 2 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 RGS12_us1 PF16613.5 EMR64531.1 - 0.8 10.0 10.1 1.2 9.5 2.3 2.6 2 0 0 2 2 2 0 Unstructured region of RGS12 HEAT_EZ PF13513.6 EMR64531.1 - 6.2 7.4 11.7 3.8 8.1 1.0 5.6 6 1 1 7 7 7 0 HEAT-like repeat Iso_dh PF00180.20 EMR64532.1 - 2.1e-70 237.6 0.0 2.4e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Helo_like_N PF17111.5 EMR64533.1 - 0.0056 16.1 0.4 0.015 14.7 0.1 1.8 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank_3 PF13606.6 EMR64533.1 - 0.15 12.7 1.1 6.8 7.6 0.0 3.9 5 0 0 5 5 5 0 Ankyrin repeat Arrestin_N PF00339.29 EMR64534.1 - 5.6e-14 52.4 0.0 1.1e-08 35.3 0.0 3.4 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain SUIM_assoc PF16619.5 EMR64534.1 - 0.0091 16.0 4.7 0.0091 16.0 4.7 2.7 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Bul1_C PF04426.12 EMR64534.1 - 0.052 12.9 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Bul1 C terminus DUF4834 PF16118.5 EMR64534.1 - 0.79 10.7 2.5 1.9 9.5 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SPX PF03105.19 EMR64534.1 - 0.9 9.4 8.3 22 4.8 8.5 2.1 1 1 0 1 1 1 0 SPX domain HABP4_PAI-RBP1 PF04774.15 EMR64535.1 - 0.066 14.1 2.6 0.098 13.5 2.6 1.4 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Meth_synt_2 PF01717.18 EMR64536.1 - 5e-06 26.0 0.0 0.00028 20.3 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Glyco_hydro_18 PF00704.28 EMR64537.1 - 2.8e-34 119.3 1.6 2.8e-34 119.3 1.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.20 EMR64537.1 - 1.4e-18 66.6 0.0 1.2e-08 34.8 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 EMR64537.1 - 4.2e-05 23.9 8.3 4.2e-05 23.9 8.3 4.0 3 1 1 4 4 4 1 Chitin recognition protein CIAPIN1 PF05093.13 EMR64539.1 - 1.7e-40 137.5 3.0 2.7e-40 136.9 3.0 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EMR64539.1 - 1.5e-22 80.2 0.0 2.2e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus AMP-binding PF00501.28 EMR64540.1 - 4.7e-74 249.5 0.0 4.9e-38 130.8 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EMR64540.1 - 8.5e-13 49.1 2.4 1.7e-12 48.1 2.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_3 PF07859.13 EMR64541.1 - 1.4e-47 162.2 0.1 1.9e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR64541.1 - 1.5e-11 43.9 0.6 2.5e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family WD40 PF00400.32 EMR64542.1 - 1.7e-18 66.6 9.6 0.0018 19.0 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR64542.1 - 3e-08 33.8 0.0 3.6e-05 24.0 0.1 4.3 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EMR64542.1 - 5.7e-05 22.6 0.0 9.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain adh_short PF00106.25 EMR64544.1 - 1e-38 132.8 0.0 1.5e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64544.1 - 7e-28 97.8 0.0 8.8e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EMR64544.1 - 3.4e-08 33.2 0.0 8.3e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMR64544.1 - 0.023 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMR64544.1 - 0.05 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Hce2 PF14856.6 EMR64545.1 - 8.5e-24 83.8 0.1 1.1e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor NmrA PF05368.13 EMR64546.1 - 4.3e-28 98.4 0.0 5.2e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR64546.1 - 7.9e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMR64546.1 - 0.049 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 EMR64546.1 - 0.049 13.1 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Tubulin PF00091.25 EMR64547.1 - 1.1e-68 231.4 0.1 1.5e-68 230.9 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMR64547.1 - 1.7e-45 154.2 0.2 5e-45 152.7 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EMR64547.1 - 9.8e-08 32.3 0.0 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain PepX_C PF08530.10 EMR64548.1 - 1.5e-18 67.5 0.0 2.8e-18 66.7 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EMR64548.1 - 0.0018 17.9 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) MDM10 PF12519.8 EMR64550.1 - 0.35 9.7 1.8 0.51 9.1 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PBP1_TM PF14812.6 EMR64550.1 - 0.96 9.9 7.0 1.3 9.5 2.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FA_hydroxylase PF04116.13 EMR64553.1 - 5.6e-06 26.7 1.2 1.5e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_2_C PF02836.17 EMR64554.1 - 2.5e-24 85.9 0.4 7.9e-24 84.3 0.1 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EMR64554.1 - 4.1e-20 72.4 0.1 2.3e-19 69.9 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EMR64554.1 - 4.1e-19 69.3 0.2 8.4e-19 68.3 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EMR64554.1 - 1.5e-05 25.5 0.0 0.0001 22.8 0.0 2.4 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Hydrolase_4 PF12146.8 EMR64555.1 - 6.8e-06 25.5 0.1 0.0021 17.4 0.1 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR64555.1 - 0.00021 21.0 0.0 0.0004 20.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR64555.1 - 0.0011 19.6 0.6 0.0025 18.4 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EMR64555.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family FoP_duplication PF13865.6 EMR64556.1 - 6.3 7.4 12.0 0.78 10.3 5.4 2.2 1 1 1 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 ketoacyl-synt PF00109.26 EMR64557.1 - 2.8e-66 223.7 0.4 5.3e-66 222.8 0.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EMR64557.1 - 5.7e-55 186.0 0.1 1.3e-54 184.9 0.1 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EMR64557.1 - 3.8e-49 167.9 0.5 7.1e-49 167.0 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 EMR64557.1 - 6.6e-43 147.1 1.1 1.2e-42 146.2 1.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EMR64557.1 - 3.9e-35 120.4 0.0 1.2e-34 118.9 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EMR64557.1 - 9.1e-17 62.4 0.0 4.7e-15 56.8 0.0 3.3 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EMR64557.1 - 1.4e-15 57.9 0.0 4.6e-15 56.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EMR64557.1 - 4.7e-15 55.7 0.3 2.9e-14 53.1 0.3 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EMR64557.1 - 2.6e-14 53.6 0.0 1.7e-12 47.8 0.0 3.0 2 1 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 EMR64557.1 - 1.2e-09 38.6 0.0 4.5e-09 36.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR64557.1 - 2.3e-09 37.3 0.0 5.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR64557.1 - 2.7e-09 37.6 0.0 1.1e-08 35.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EMR64557.1 - 3e-09 36.6 0.2 8.5e-09 35.2 0.0 1.8 2 0 0 2 2 1 1 short chain dehydrogenase Methyltransf_31 PF13847.6 EMR64557.1 - 9.9e-09 35.2 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR64557.1 - 1.9e-07 31.3 0.0 7.7e-07 29.4 0.0 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EMR64557.1 - 1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 EMR64557.1 - 5.4e-05 22.9 0.5 0.00028 20.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EMR64557.1 - 0.00018 21.0 0.2 0.00041 19.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EMR64557.1 - 0.004 17.0 0.8 0.013 15.4 0.8 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF938 PF06080.12 EMR64557.1 - 0.13 12.0 0.0 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Abhydrolase_6 PF12697.7 EMR64558.1 - 0.0001 23.0 1.1 0.00017 22.3 1.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tautomerase_3 PF14832.6 EMR64559.1 - 6.4e-13 49.1 0.0 8.3e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Rubrerythrin PF02915.17 EMR64559.1 - 0.038 14.4 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 Rubrerythrin MFS_1 PF07690.16 EMR64560.1 - 3e-10 39.6 12.0 4.6e-10 39.0 12.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4752 PF15944.5 EMR64560.1 - 0.2 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) Sugar_tr PF00083.24 EMR64561.1 - 3.1e-99 332.9 17.2 3.7e-99 332.6 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR64561.1 - 6.6e-27 94.4 50.4 4.3e-23 81.8 25.5 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF3792 PF12670.7 EMR64561.1 - 2.7 8.2 16.2 0.15 12.3 1.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) VCBS PF13517.6 EMR64562.1 - 1e-28 99.7 50.7 8.3e-12 45.5 1.7 7.7 3 2 5 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EMR64562.1 - 1.8e-12 48.0 1.5 1.8e-12 48.0 1.5 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR64562.1 - 9.4e-09 35.5 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 EMR64562.1 - 2.6e-07 30.2 4.8 0.14 11.5 0.0 5.8 4 2 2 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 EMR64562.1 - 1.1e-05 25.5 32.8 0.0014 18.7 0.3 6.3 6 0 0 6 6 6 4 FG-GAP repeat PliI PF16743.5 EMR64562.1 - 0.11 12.2 0.9 11 5.8 0.0 3.9 5 0 0 5 5 5 0 Periplasmic lysozyme inhibitor of I-type lysozyme Ank_2 PF12796.7 EMR64563.1 - 5.7e-17 62.1 3.2 6.3e-09 36.3 0.1 2.5 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR64563.1 - 3.1e-11 43.6 0.7 7.8e-07 29.5 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) CorA PF01544.18 EMR64563.1 - 1.7e-09 37.4 0.1 4.2e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TPR_12 PF13424.6 EMR64563.1 - 1.8e-07 31.3 0.1 0.00027 21.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Ank_5 PF13857.6 EMR64563.1 - 5.7e-07 29.7 1.1 0.00033 20.9 0.3 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR64563.1 - 4.7e-06 26.5 0.5 0.071 13.7 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EMR64563.1 - 0.00019 21.7 0.1 0.056 13.9 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat TPR_7 PF13176.6 EMR64563.1 - 0.017 15.1 0.1 5.4 7.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat VWA_3_C PF18571.1 EMR64563.1 - 0.054 13.4 0.2 17 5.4 0.0 3.5 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain TPR_10 PF13374.6 EMR64563.1 - 0.079 12.9 1.2 7.4 6.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4709 PF15821.5 EMR64563.1 - 1.6 9.0 4.4 2.3 8.5 1.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4709) adh_short PF00106.25 EMR64565.1 - 2.8e-20 72.6 0.0 3.4e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64565.1 - 2.3e-08 33.9 0.0 3.1e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64565.1 - 5.5e-08 32.9 0.1 6.9e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF2456 PF10445.9 EMR64566.1 - 3.3e-09 36.7 1.4 6.6e-09 35.7 1.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2456) cobW PF02492.19 EMR64567.1 - 4.5e-34 117.6 0.0 5.6e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EMR64567.1 - 1.3e-06 27.6 0.2 0.00041 19.4 0.1 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EMR64567.1 - 0.0063 16.6 0.0 0.019 15.1 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EMR64567.1 - 0.0064 17.0 0.0 0.0096 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EMR64567.1 - 0.028 14.4 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EMR64567.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMR64567.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain TMEM51 PF15345.6 EMR64567.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Pox_A32 PF04665.12 EMR64567.1 - 0.24 10.8 0.0 0.34 10.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Mif2_N PF15624.6 EMR64568.1 - 5.4e-34 117.8 3.6 5.4e-34 117.8 3.6 3.8 2 1 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 EMR64568.1 - 1.5e-31 108.5 0.2 2.9e-31 107.5 0.2 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EMR64568.1 - 9.5e-08 31.7 0.0 2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EMR64568.1 - 0.032 13.9 0.1 0.091 12.5 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF861) BING4CT PF08149.11 EMR64569.1 - 1.4e-39 133.7 0.0 5e-36 122.4 0.0 3.5 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EMR64569.1 - 1.2e-05 25.6 0.0 5.4 7.4 0.0 5.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EMR64569.1 - 0.0053 15.9 0.1 0.025 13.7 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EMR64569.1 - 0.017 16.0 0.0 91 4.2 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat HET PF06985.11 EMR64570.1 - 1.4e-19 70.9 0.1 3.3e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNase_HII PF01351.18 EMR64571.1 - 8.7e-45 153.0 0.0 1.5e-39 135.9 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease HII RIBIOP_C PF04950.12 EMR64572.1 - 4.5e-106 354.5 0.0 9e-106 353.6 0.0 1.5 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EMR64572.1 - 1.6e-20 73.0 0.0 4.4e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BNIP2 PF12496.8 EMR64572.1 - 1 9.8 10.0 21 5.6 10.0 2.5 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Sigma_reg_N PF13800.6 EMR64573.1 - 0.0024 18.1 3.5 0.4 11.0 0.1 3.8 3 1 1 4 4 4 2 Sigma factor regulator N-terminal ETRAMP PF09716.10 EMR64573.1 - 0.32 11.1 1.3 0.75 9.9 0.1 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RHD3 PF05879.12 EMR64574.1 - 4.4e-291 967.5 0.0 8e-289 960.0 0.0 2.0 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EMR64574.1 - 4.3e-07 29.5 0.0 7.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EMR64574.1 - 1.4e-06 28.5 0.0 3.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EMR64574.1 - 4.1e-06 26.8 0.0 9.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EMR64574.1 - 0.00052 20.3 0.0 0.002 18.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Cys_Met_Meta_PP PF01053.20 EMR64574.1 - 0.09 11.3 0.2 0.14 10.6 0.2 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Septin PF00735.18 EMR64574.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.12 EMR64575.1 - 1.6e-06 28.1 0.0 3.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMR64575.1 - 0.003 18.0 0.0 0.034 14.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 EMR64575.1 - 0.0053 16.1 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 EMR64575.1 - 0.0062 16.8 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EMR64575.1 - 0.033 14.5 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EMR64575.1 - 0.055 12.6 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SRF-TF PF00319.18 EMR64576.1 - 7.5e-24 83.0 0.2 9.7e-24 82.6 0.2 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.8 EMR64578.1 - 4.1e-170 566.2 1.1 6.2e-170 565.6 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Ala_racemase_N PF01168.20 EMR64579.1 - 3.7e-13 49.6 0.0 5.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Metallophos_2 PF12850.7 EMR64580.1 - 1.4e-06 28.6 0.6 5.2e-06 26.7 0.0 2.2 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase superfamily domain PT PF04886.12 EMR64580.1 - 2 8.0 10.3 3.6 7.2 10.3 1.4 1 0 0 1 1 1 0 PT repeat Podoplanin PF05808.11 EMR64581.1 - 0.0062 16.6 0.2 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 Podoplanin Mucin15 PF15672.5 EMR64581.1 - 0.01 15.3 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 TAL_FSA PF00923.19 EMR64582.1 - 8.9e-92 307.5 1.0 1e-91 307.3 1.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 EMR64582.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Cas_VVA1548 PF09652.10 EMR64582.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) GMC_oxred_N PF00732.19 EMR64584.1 - 1.5e-40 139.5 0.1 2.6e-33 115.7 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR64584.1 - 7.8e-23 81.6 0.0 1.8e-22 80.4 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMR64584.1 - 3.6e-05 23.0 0.1 0.00013 21.2 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMR64584.1 - 6.5e-05 23.1 0.0 0.00021 21.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR64584.1 - 0.00011 22.0 0.2 0.00021 21.0 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR64584.1 - 0.00081 18.7 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR64584.1 - 0.00097 19.7 0.0 0.42 11.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase BolA PF01722.18 EMR64585.1 - 3.1e-30 104.3 0.5 3.8e-30 104.0 0.5 1.1 1 0 0 1 1 1 1 BolA-like protein Sulfotransfer_4 PF17784.1 EMR64586.1 - 4.3e-52 177.1 0.1 5.5e-52 176.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR64586.1 - 0.00023 21.6 1.0 0.0041 17.5 0.1 2.2 1 1 0 2 2 2 1 Sulfotransferase family RNA_pol_Rpc34 PF05158.12 EMR64587.1 - 4.3e-79 266.3 0.0 5.2e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_27 PF13463.6 EMR64587.1 - 0.0071 16.8 0.1 0.019 15.5 0.1 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 EMR64587.1 - 0.0077 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC GntR PF00392.21 EMR64587.1 - 0.12 12.0 0.1 20 4.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_36 PF13730.6 EMR64587.1 - 0.13 12.2 0.1 0.91 9.5 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PIP5K PF01504.18 EMR64590.1 - 1.8e-37 129.1 0.6 9.3e-28 97.2 0.5 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase baeRF_family5 PF18846.1 EMR64590.1 - 0.028 14.6 0.1 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 MMM1 PF10296.9 EMR64591.1 - 1.8e-06 27.3 0.0 1.1e-05 24.6 0.0 2.1 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Oxidored_FMN PF00724.20 EMR64592.1 - 3.3e-72 243.6 0.0 3.9e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 EMR64592.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme AP_endonuc_2 PF01261.24 EMR64592.1 - 0.13 11.7 0.0 3.6 7.0 0.0 2.7 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel AMP-binding PF00501.28 EMR64594.1 - 1.2e-66 225.1 0.0 8.6e-34 116.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EMR64594.1 - 2.6e-12 47.5 0.5 7.6e-12 46.0 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans_2 PF11951.8 EMR64595.1 - 2.4e-40 138.5 0.0 4e-39 134.5 0.0 2.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR64595.1 - 2.7e-07 30.6 6.7 2.7e-07 30.6 6.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ctr PF04145.15 EMR64596.1 - 1.5e-40 139.2 0.2 1.8e-40 139.0 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.6 EMR64596.1 - 0.014 15.4 0.3 6 6.9 0.0 2.1 2 0 0 2 2 2 0 Putative sensor DUF4834 PF16118.5 EMR64596.1 - 0.08 13.9 0.0 2.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2530 PF10745.9 EMR64596.1 - 0.7 10.2 8.9 2.9 8.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) LapA_dom PF06305.11 EMR64596.1 - 6 6.8 6.7 55 3.7 0.0 2.4 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Oxidored_q3 PF00499.20 EMR64596.1 - 9.8 5.9 9.9 0.82 9.4 0.9 2.1 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MFS_1 PF07690.16 EMR64597.1 - 2.1e-46 158.5 64.4 1.8e-45 155.4 59.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR64597.1 - 5.7e-21 74.6 19.0 7.7e-21 74.1 19.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMR64597.1 - 9.4e-14 51.1 12.5 9.4e-14 51.1 12.5 3.2 2 1 0 3 3 3 1 Sugar (and other) transporter GST_N_2 PF13409.6 EMR64598.1 - 1e-21 77.0 0.0 2.2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR64598.1 - 2.1e-13 50.1 0.1 8.3e-13 48.2 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR64598.1 - 6.3e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR64598.1 - 0.00021 21.6 0.0 0.003 17.9 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR64598.1 - 0.00054 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MARVEL PF01284.23 EMR64599.1 - 9.1e-05 22.5 8.5 0.00025 21.1 8.5 1.7 1 1 0 1 1 1 1 Membrane-associating domain Zip PF02535.22 EMR64601.1 - 1e-33 117.0 0.0 1.2e-33 116.8 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter THOC2_N PF16134.5 EMR64601.1 - 0.086 11.5 0.2 0.12 11.0 0.2 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Peptidase_S8 PF00082.22 EMR64605.1 - 8.4e-33 113.9 10.7 1.1e-32 113.5 10.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR64605.1 - 3.1e-17 63.0 0.1 6.9e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 TFIIA PF03153.13 EMR64606.1 - 0.026 14.5 8.3 0.028 14.4 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EMR64606.1 - 0.79 9.3 15.4 1.2 8.7 15.4 1.2 1 0 0 1 1 1 0 Spt20 family GST_N PF02798.20 EMR64607.1 - 7.2e-07 29.5 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMR64607.1 - 1.4e-06 28.5 0.0 3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR64607.1 - 1.8e-05 24.8 0.0 3.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR64607.1 - 2.1e-05 24.6 0.0 4.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR64607.1 - 0.00051 20.0 0.0 0.00096 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR64607.1 - 0.0013 19.1 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DAO PF01266.24 EMR64608.1 - 7.1e-10 39.0 0.4 2.5e-07 30.6 0.4 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR64608.1 - 1.1e-08 35.1 0.0 2.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR64608.1 - 1.6e-05 24.3 0.0 0.0035 16.6 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR64608.1 - 0.0001 21.7 0.0 0.17 11.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMR64608.1 - 0.00022 19.8 0.1 0.0064 15.0 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 EMR64608.1 - 0.00026 20.3 0.0 0.00063 19.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 EMR64608.1 - 0.0006 19.2 0.1 0.0037 16.6 0.0 2.0 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.22 EMR64608.1 - 0.001 18.2 0.0 0.35 9.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 EMR64608.1 - 0.0074 16.8 0.0 0.11 13.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EMR64608.1 - 0.015 13.9 0.0 2.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 EMR64608.1 - 0.042 12.9 0.0 0.72 8.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 EMR64608.1 - 0.1 11.7 1.1 8.7 5.4 0.0 3.0 4 0 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EMR64608.1 - 0.12 11.4 0.1 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 EMR64609.1 - 7.6e-41 140.2 51.8 3.6e-39 134.7 51.8 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR64609.1 - 3.7e-14 52.1 20.3 2.9e-13 49.1 19.7 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMR64609.1 - 0.0022 16.4 3.5 0.0022 16.4 3.5 3.8 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family DUF4448 PF14610.6 EMR64609.1 - 0.19 11.5 0.1 0.19 11.5 0.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) ENTH PF01417.20 EMR64610.1 - 1.1e-29 103.0 0.2 2e-29 102.2 0.2 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EMR64610.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Pkinase PF00069.25 EMR64611.1 - 1.1e-33 116.7 0.0 1.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64611.1 - 1.6e-17 63.7 0.0 3.1e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR64611.1 - 0.0057 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF4263 PF14082.6 EMR64611.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) IF4E PF01652.18 EMR64613.1 - 2.4e-54 183.4 0.1 3e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DAO PF01266.24 EMR64614.1 - 5.8e-20 72.2 0.0 1.6e-15 57.6 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR64614.1 - 0.00015 22.2 0.2 0.00035 21.1 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR64614.1 - 0.0037 16.4 0.1 0.0087 15.2 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 EMR64614.1 - 0.0046 16.6 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EMR64614.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR64614.1 - 0.013 15.7 0.1 0.03 14.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EMR64614.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMR64614.1 - 0.038 14.4 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EMR64614.1 - 0.06 12.9 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EMR64614.1 - 0.062 12.6 0.1 0.094 12.0 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EMR64614.1 - 0.075 12.3 0.4 0.12 11.6 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EMR64614.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Glu_dehyd_C PF16912.5 EMR64614.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus GIDA PF01134.22 EMR64614.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pro_isomerase PF00160.21 EMR64615.1 - 5.3e-41 140.5 0.3 6.1e-41 140.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3391 PF11871.8 EMR64617.1 - 0.48 11.0 2.9 1.8 9.1 2.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) TPR_1 PF00515.28 EMR64618.1 - 4e-43 143.5 29.1 2.3e-06 27.2 0.1 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat STI1 PF17830.1 EMR64618.1 - 1.3e-35 121.1 12.9 1.4e-19 69.8 1.1 2.8 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 EMR64618.1 - 4.1e-34 113.9 26.1 5.2e-05 23.1 0.1 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 EMR64618.1 - 8.8e-20 70.1 18.1 0.00011 21.8 0.1 7.1 7 0 0 7 7 7 5 TPR repeat TPR_8 PF13181.6 EMR64618.1 - 1.8e-19 68.2 25.3 9.6e-06 25.4 0.3 9.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMR64618.1 - 6.9e-14 51.4 9.7 0.35 11.8 0.0 8.4 5 3 4 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EMR64618.1 - 2.8e-13 50.3 6.3 0.0074 16.9 0.0 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMR64618.1 - 3.7e-13 49.8 7.0 0.035 14.6 0.4 6.8 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 EMR64618.1 - 8.8e-13 48.2 3.3 0.00036 20.6 0.0 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMR64618.1 - 1e-12 48.1 10.6 3.3e-08 33.7 0.3 6.1 3 3 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMR64618.1 - 3.2e-12 45.9 4.9 0.078 13.4 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMR64618.1 - 8.5e-09 34.8 7.9 0.0017 18.2 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 EMR64618.1 - 1e-07 31.6 4.5 1.8 8.6 0.1 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat DUF5113 PF17140.4 EMR64618.1 - 0.02 14.7 4.8 1.7 8.4 0.2 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) SHNi-TPR PF10516.9 EMR64618.1 - 0.03 13.8 0.4 20 4.8 0.0 3.7 3 0 0 3 3 3 0 SHNi-TPR TPR_6 PF13174.6 EMR64618.1 - 0.07 13.8 16.9 1.9 9.3 0.0 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF2939 PF11159.8 EMR64618.1 - 0.41 11.1 1.9 1.6 9.2 0.0 3.0 2 1 1 3 3 2 0 Protein of unknown function (DUF2939) TPM_phosphatase PF04536.14 EMR64618.1 - 0.48 10.6 4.1 31 4.7 0.0 3.8 4 0 0 4 4 4 0 TPM domain ANAPC3 PF12895.7 EMR64618.1 - 1.6 9.0 10.1 9.6 6.5 1.7 3.8 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Trypan_PARP PF05887.11 EMR64618.1 - 3.9 7.5 21.4 0.4 10.7 15.9 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) p450 PF00067.22 EMR64619.1 - 1.9e-51 175.3 0.0 4.9e-33 114.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 60KD_IMP PF02096.20 EMR64620.1 - 0.00095 19.1 0.0 0.0083 16.0 0.0 2.1 2 0 0 2 2 2 1 60Kd inner membrane protein DUF4129 PF13559.6 EMR64621.1 - 2.9e-05 24.3 0.0 0.00015 21.9 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 EMR64621.1 - 0.0016 18.5 5.9 0.029 14.4 0.0 2.6 3 0 0 3 3 3 2 NICE-3 protein DUF3810 PF12725.7 EMR64621.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ebola_NP PF05505.12 EMR64621.1 - 0.25 9.6 0.4 0.33 9.2 0.4 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein PIG-P PF08510.12 EMR64621.1 - 1.3 9.0 4.2 2.6 8.0 4.2 1.4 1 0 0 1 1 1 0 PIG-P SieB PF14163.6 EMR64621.1 - 2.1 7.8 6.1 4.9 6.6 6.1 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B TcpE PF12648.7 EMR64621.1 - 2.9 8.5 7.4 4.9 7.8 7.4 1.3 1 0 0 1 1 1 0 TcpE family DUF829 PF05705.14 EMR64623.1 - 2.6e-32 112.6 0.0 3.1e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Syntaxin_2 PF14523.6 EMR64624.1 - 1.3e-24 86.4 1.0 1.3e-24 86.4 1.0 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EMR64624.1 - 7.3e-14 51.5 0.9 1.4e-13 50.6 0.9 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EMR64624.1 - 0.0058 16.3 10.8 0.084 12.5 10.8 2.5 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 EMR64624.1 - 0.061 13.1 0.1 0.34 10.7 0.2 2.1 2 0 0 2 2 2 0 Synaptobrevin SH3BGR PF04908.15 EMR64624.1 - 0.066 13.4 2.4 1.5 9.0 0.1 2.4 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein EF-hand_14 PF17959.1 EMR64624.1 - 0.094 13.1 0.4 0.26 11.7 0.4 1.8 1 1 0 1 1 1 0 EF-hand domain DUF5089 PF17002.5 EMR64624.1 - 0.097 12.5 0.2 0.097 12.5 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5089) CEP209_CC5 PF16574.5 EMR64624.1 - 0.1 12.8 10.5 0.37 10.9 0.3 2.9 2 1 1 3 3 3 0 Coiled-coil region of centrosome protein CE290 T2SSF PF00482.23 EMR64624.1 - 0.24 11.3 2.2 0.62 10.0 0.8 2.4 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF1664 PF07889.12 EMR64624.1 - 0.84 9.7 4.9 1.1 9.3 1.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 EMR64624.1 - 0.88 9.4 5.7 1.1 9.1 1.2 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UPF0242 PF06785.11 EMR64624.1 - 6.5 6.8 12.7 9.4 6.3 9.7 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ndc1_Nup PF09531.10 EMR64625.1 - 3.4e-179 597.5 0.3 3.9e-179 597.3 0.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup ALG11_N PF15924.5 EMR64626.1 - 1.8e-83 279.7 0.0 3.2e-83 278.9 0.0 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EMR64626.1 - 9.9e-21 74.0 0.0 1.9e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMR64626.1 - 3.7e-10 40.3 0.0 9.5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 MoaE PF02391.17 EMR64626.1 - 0.093 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 MoaE protein Glyco_transf_4 PF13439.6 EMR64626.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase Family 4 SPOB_a PF14689.6 EMR64626.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain Adap_comp_sub PF00928.21 EMR64627.1 - 2e-18 66.7 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMR64627.1 - 3.1e-07 30.4 0.2 5.3e-07 29.7 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EMR64627.1 - 0.0029 18.0 0.2 0.0051 17.2 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) ADH_N PF08240.12 EMR64628.1 - 9e-29 99.6 0.6 1.7e-28 98.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR64628.1 - 8.7e-25 87.2 0.2 1.4e-24 86.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR64628.1 - 0.00016 22.8 0.1 0.00024 22.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR64628.1 - 0.014 14.7 0.3 0.024 13.9 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EMR64628.1 - 0.075 12.4 1.5 0.13 11.6 0.5 1.7 2 0 0 2 2 2 0 ThiF family adh_short PF00106.25 EMR64628.1 - 0.13 11.7 0.4 0.27 10.7 0.4 1.6 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 EMR64628.1 - 0.16 11.3 0.1 0.33 10.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2420 PF10336.9 EMR64629.1 - 2.9e-05 24.1 0.0 0.0021 18.0 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2420) Pro_isomerase PF00160.21 EMR64630.1 - 2.7e-46 157.7 0.0 6.1e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EMR64630.1 - 6.2e-06 26.3 0.0 1.8e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EMR64630.1 - 0.0003 20.9 0.0 0.00073 19.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 EMR64630.1 - 0.0035 16.8 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger AMP-binding PF00501.28 EMR64631.1 - 3.4e-70 236.8 0.0 4.2e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR64631.1 - 9.8e-21 74.5 0.1 2.8e-20 73.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KTI12 PF08433.10 EMR64632.1 - 2e-74 250.5 0.0 2.9e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EMR64632.1 - 0.0002 21.5 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMR64632.1 - 0.0039 17.5 0.0 0.0073 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain GT-D PF08759.11 EMR64632.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase GT-D fold AAA_18 PF13238.6 EMR64632.1 - 0.032 14.8 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMR64632.1 - 0.04 14.3 0.1 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain 6PF2K PF01591.18 EMR64632.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_14 PF13173.6 EMR64632.1 - 0.11 12.5 0.1 0.7 9.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain Alg6_Alg8 PF03155.15 EMR64633.1 - 7.2e-46 157.2 7.1 8.6e-46 156.9 7.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lung_7-TM_R PF06814.13 EMR64634.1 - 1.6e-52 178.6 15.3 9.3e-41 140.0 9.8 2.1 1 1 1 2 2 2 2 Lung seven transmembrane receptor MIG-14_Wnt-bd PF06664.12 EMR64635.1 - 0.0055 16.0 0.7 0.54 9.4 1.0 2.2 1 1 1 2 2 2 2 Wnt-binding factor required for Wnt secretion Methyltransf_28 PF02636.17 EMR64636.1 - 8e-84 281.3 0.0 9.4e-84 281.1 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lectin_leg-like PF03388.13 EMR64637.1 - 1.1e-21 77.3 0.0 2.2e-21 76.3 0.0 1.5 2 0 0 2 2 2 1 Legume-like lectin family Baculo_PEP_C PF04513.12 EMR64637.1 - 0.018 15.1 0.1 3.7 7.6 0.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFIIA PF03153.13 EMR64637.1 - 0.031 14.3 7.3 0.04 13.9 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EMR64637.1 - 0.14 11.8 8.8 0.2 11.2 8.8 1.2 1 0 0 1 1 1 0 Spt20 family Tropomyosin_1 PF12718.7 EMR64637.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.3 2 1 0 2 2 2 0 Tropomyosin like DUF4175 PF13779.6 EMR64637.1 - 0.17 9.7 12.5 0.26 9.1 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2514 PF10721.9 EMR64637.1 - 0.45 10.5 3.9 0.79 9.7 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ANAPC4 PF12896.7 EMR64639.1 - 9.3e-29 100.4 0.0 2e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EMR64639.1 - 4.4e-19 68.6 0.1 1.5e-18 66.8 0.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TruB-C_2 PF09157.11 EMR64639.1 - 0.0056 16.7 0.2 5.7 7.1 0.0 2.9 2 0 0 2 2 2 2 Pseudouridine synthase II TruB, C-terminal WD40 PF00400.32 EMR64639.1 - 0.14 13.1 0.0 1.7 9.6 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Pkinase PF00069.25 EMR64640.1 - 8.6e-54 182.7 0.0 1.2e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64640.1 - 1.7e-21 76.7 0.0 3.5e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMR64640.1 - 0.00045 20.2 4.8 0.00058 19.8 0.1 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EMR64640.1 - 0.0062 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMR64640.1 - 0.0081 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TAF4 PF05236.14 EMR64640.1 - 0.047 13.4 12.7 0.073 12.8 12.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Sporozoite_P67 PF05642.11 EMR64640.1 - 2.3 6.2 6.9 3.2 5.7 6.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WAC_Acf1_DNA_bd PF10537.9 EMR64641.1 - 1.7e-39 134.4 1.2 3.3e-39 133.5 0.0 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EMR64641.1 - 2.3e-17 63.3 0.1 2.3e-17 63.3 0.1 3.3 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EMR64641.1 - 1.1e-16 60.8 0.2 2e-16 60.0 0.2 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EMR64641.1 - 3.2e-06 26.5 1.0 2.4e-05 23.7 0.0 2.7 3 0 0 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 1 SLX9 PF15341.6 EMR64641.1 - 0.011 16.2 0.6 0.011 16.2 0.6 4.1 4 0 0 4 4 4 0 Ribosome biogenesis protein SLX9 Spt5_N PF11942.8 EMR64641.1 - 4.1 8.5 29.4 1.9 9.5 6.2 3.7 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.6 EMR64641.1 - 8.4 6.7 16.5 0.23 11.7 1.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) MFS_1 PF07690.16 EMR64643.1 - 1.5e-25 89.9 24.1 3.3e-15 55.9 4.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR64643.1 - 9e-08 31.4 4.5 9e-08 31.4 4.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EMR64643.1 - 0.00011 21.6 3.0 0.0017 17.7 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Tom22 PF04281.13 EMR64644.1 - 3e-50 169.6 0.1 3.5e-50 169.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 UPF0444 PF15475.6 EMR64644.1 - 0.067 13.5 3.6 0.11 12.8 0.5 2.1 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Mid2 PF04478.12 EMR64645.1 - 0.03 14.2 5.6 5.1 6.9 6.8 2.4 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor PfkB PF00294.24 EMR64646.1 - 3.4e-67 226.9 0.3 3.9e-67 226.7 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMR64646.1 - 3e-05 23.5 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DOT1 PF08123.13 EMR64647.1 - 9.9e-70 234.2 0.0 1.6e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 RE_SinI PF09570.10 EMR64647.1 - 0.021 14.1 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 SinI restriction endonuclease Aft1_HRR PF11787.8 EMR64647.1 - 3.1 9.0 5.4 48 5.2 1.0 2.8 2 0 0 2 2 2 0 Aft1 HRR domain Scytalone_dh PF02982.14 EMR64648.1 - 2.8e-88 293.7 0.4 3.3e-88 293.5 0.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EMR64648.1 - 2.3e-09 37.5 0.3 3.1e-09 37.0 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain Dynamin_N PF00350.23 EMR64649.1 - 2.6e-36 125.2 0.0 5.9e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EMR64649.1 - 2.2e-18 66.5 0.6 4e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EMR64649.1 - 5e-05 23.4 0.1 0.00029 20.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2478 PF10649.9 EMR64649.1 - 0.043 13.4 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) ALIX_LYPXL_bnd PF13949.6 EMR64649.1 - 0.058 12.7 0.2 0.17 11.2 0.2 1.9 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_15 PF13175.6 EMR64649.1 - 0.1 12.3 0.5 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain zf-C2H2 PF00096.26 EMR64650.1 - 0.035 14.6 10.2 1.6 9.4 0.6 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 EMR64650.1 - 0.045 13.3 0.5 0.083 12.5 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type Ank_2 PF12796.7 EMR64652.1 - 2.1e-54 182.1 0.0 2.5e-06 28.0 0.0 11.0 7 3 2 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR64652.1 - 3.9e-42 142.1 9.2 4.1e-06 27.2 0.1 13.5 8 3 5 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.30 EMR64652.1 - 8.7e-37 124.0 16.7 5.4e-06 26.6 0.0 15.2 15 1 1 16 16 16 10 Ankyrin repeat Ank_3 PF13606.6 EMR64652.1 - 1.6e-32 107.8 14.1 6.4e-06 26.1 0.1 15.5 18 0 0 18 18 18 8 Ankyrin repeat Ank_5 PF13857.6 EMR64652.1 - 2.9e-31 107.1 6.8 0.0018 18.5 0.0 11.8 9 2 4 13 13 13 7 Ankyrin repeats (many copies) RRM_1 PF00076.22 EMR64653.1 - 1.8e-05 24.4 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR_2 PF13233.6 EMR64654.1 - 4.2e-07 30.6 0.4 5.7e-07 30.2 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EMR64654.1 - 4.7e-06 26.6 0.3 1.3e-05 25.1 0.3 1.8 2 1 0 2 2 2 1 Complex 1 protein (LYR family) NodA PF02474.15 EMR64654.1 - 0.14 11.8 0.4 3.7 7.2 0.0 2.1 1 1 1 2 2 2 0 Nodulation protein A (NodA) G10 PF01125.17 EMR64655.1 - 1.7e-63 212.8 4.8 1.9e-63 212.6 4.8 1.0 1 0 0 1 1 1 1 G10 protein p450 PF00067.22 EMR64657.1 - 5.2e-57 193.6 0.0 7.1e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.21 EMR64658.1 - 1.1e-32 113.0 3.9 1.9e-32 112.1 3.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.25 EMR64659.1 - 7.6e-47 159.9 0.0 1.1e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64659.1 - 8.2e-24 84.3 0.0 1.9e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMR64659.1 - 0.00017 21.6 0.1 0.00017 21.6 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMR64659.1 - 0.0011 18.6 0.3 0.0041 16.8 0.3 1.8 1 1 0 1 1 1 1 RIO1 family Jun PF03957.13 EMR64659.1 - 0.11 12.4 11.8 0.18 11.7 11.8 1.3 1 0 0 1 1 1 0 Jun-like transcription factor Choline_kinase PF01633.20 EMR64659.1 - 0.12 11.9 2.8 0.2 11.2 0.2 2.4 2 1 1 3 3 3 0 Choline/ethanolamine kinase TFIIA PF03153.13 EMR64659.1 - 9 6.2 13.9 13 5.6 13.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EST1_DNA_bind PF10373.9 EMR64660.1 - 7.3e-23 81.4 0.1 2.1e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EMR64660.1 - 1.2e-11 45.4 0.5 3.3e-11 44.0 0.5 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 DUF2937 PF11157.8 EMR64660.1 - 0.09 12.5 0.1 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FAD_binding_4 PF01565.23 EMR64661.1 - 6e-08 32.5 5.4 3.9e-07 29.9 0.7 2.5 2 1 1 3 3 3 2 FAD binding domain BBE PF08031.12 EMR64661.1 - 4.6e-07 29.8 0.2 1.3e-06 28.4 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like ATG16 PF08614.11 EMR64662.1 - 4.3e-56 190.3 6.4 5.2e-56 190.1 6.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 EMR64662.1 - 1.8e-05 24.0 3.5 0.00017 20.8 3.4 1.9 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region Golgin_A5 PF09787.9 EMR64662.1 - 0.0053 16.3 4.8 0.0073 15.8 4.8 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 APG6_N PF17675.1 EMR64662.1 - 0.069 13.7 9.3 0.34 11.4 5.0 2.5 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF4201 PF13870.6 EMR64662.1 - 0.094 12.4 6.6 0.2 11.4 6.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) SRP-alpha_N PF04086.13 EMR64662.1 - 0.099 12.5 6.0 0.14 12.1 6.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal bZIP_1 PF00170.21 EMR64662.1 - 0.11 12.6 9.7 0.71 10.0 0.0 3.8 2 1 2 4 4 4 0 bZIP transcription factor YabA PF06156.13 EMR64662.1 - 0.17 12.5 6.3 2.4 8.9 2.6 3.0 2 1 1 3 3 3 0 Initiation control protein YabA Cep57_MT_bd PF06657.13 EMR64662.1 - 0.23 11.9 6.5 5.8 7.4 1.4 3.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Metal_resist PF13801.6 EMR64662.1 - 0.28 11.4 9.6 0.19 11.9 6.9 2.0 1 1 1 2 2 2 0 Heavy-metal resistance DUF737 PF05300.11 EMR64662.1 - 0.53 10.6 6.5 0.67 10.3 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Uds1 PF15456.6 EMR64662.1 - 0.64 10.2 6.9 0.41 10.8 4.8 1.7 2 0 0 2 2 2 0 Up-regulated During Septation FUSC PF04632.12 EMR64662.1 - 0.84 8.1 6.3 0.42 9.1 2.7 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family ZapB PF06005.12 EMR64662.1 - 1.3 9.5 11.7 20 5.7 2.8 3.6 2 1 0 3 3 3 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 EMR64662.1 - 1.3 9.2 9.1 1.5 9.0 2.1 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 EMR64662.1 - 3.1 8.5 12.5 10 6.8 0.1 3.7 2 2 1 3 3 3 0 SlyX HET PF06985.11 EMR64663.1 - 1.7e-11 44.7 7.7 5.4e-09 36.5 0.3 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF3256 PF11644.8 EMR64663.1 - 0.033 13.7 0.3 0.051 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) p450 PF00067.22 EMR64664.1 - 3.6e-27 95.2 0.0 4.9e-22 78.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 RRM_1 PF00076.22 EMR64665.1 - 3.1e-61 203.1 0.0 1.2e-21 76.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMR64665.1 - 1.5e-10 40.8 0.0 4.1e-06 26.4 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMR64665.1 - 9.9e-10 38.1 0.0 0.0095 15.8 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EMR64665.1 - 2.1e-07 30.8 0.1 0.075 13.0 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 EMR64665.1 - 0.00052 20.2 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain RRM_7 PF16367.5 EMR64665.1 - 0.0014 18.7 0.1 1.5 9.0 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif Cas_Cas2CT1978 PF09707.10 EMR64665.1 - 0.0022 18.0 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) SET_assoc PF11767.8 EMR64665.1 - 0.047 13.3 0.0 9.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.8 EMR64665.1 - 0.069 13.2 0.0 9.2 6.4 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 RRM_3 PF08777.11 EMR64665.1 - 0.14 12.2 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif RNA_pol_L_2 PF13656.6 EMR64667.1 - 2.2e-32 110.7 0.0 2.9e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EMR64667.1 - 3.8e-14 51.9 0.0 5.6e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Terpene_synth_C PF03936.16 EMR64669.1 - 0.037 13.4 0.1 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain 2OG-Fe_Oxy_2 PF10014.9 EMR64670.1 - 2.9e-46 157.7 0.2 3.5e-46 157.4 0.2 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase Nha1_C PF08619.10 EMR64671.1 - 3.6e-124 415.5 46.2 5.6e-119 398.4 35.9 2.1 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EMR64671.1 - 3.5e-74 249.9 20.2 4.2e-74 249.6 20.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Colicin_E5 PF12106.8 EMR64671.1 - 0.006 16.9 3.6 0.12 12.6 1.4 2.7 1 1 1 2 2 2 1 Colicin E5 ribonuclease domain FlgD_ig PF13860.6 EMR64671.1 - 0.096 12.6 0.2 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 FlgD Ig-like domain YrhC PF14143.6 EMR64671.1 - 0.11 12.6 3.4 0.19 11.8 0.2 2.6 2 0 0 2 2 2 0 YrhC-like protein p450 PF00067.22 EMR64672.1 - 1.3e-55 189.0 0.0 1.6e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4909 PF16253.5 EMR64673.1 - 0.025 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) Ribosomal_L2_C PF03947.18 EMR64674.1 - 4e-42 143.4 4.2 6.6e-42 142.7 4.2 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EMR64674.1 - 2.8e-14 52.8 0.1 6.9e-14 51.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.16 EMR64675.1 - 2.5e-26 92.5 27.6 2.6e-26 92.4 26.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily COX14 PF14880.6 EMR64675.1 - 0.1 12.5 0.1 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF2304 PF10066.9 EMR64675.1 - 8.4 6.7 9.0 0.72 10.1 0.4 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Pkinase PF00069.25 EMR64676.1 - 0.045 13.1 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain CENP-F_leu_zip PF10473.9 EMR64677.1 - 1.9e-07 31.2 92.0 0.088 12.8 12.5 8.1 2 2 5 7 7 7 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EMR64677.1 - 0.00013 21.0 30.1 0.00013 21.0 30.1 4.8 1 1 4 5 5 5 1 Calcium binding and coiled-coil domain (CALCOCO1) like APG6_N PF17675.1 EMR64677.1 - 0.00046 20.7 111.5 0.045 14.3 11.4 8.5 2 2 6 8 8 8 4 Apg6 coiled-coil region JIP_LZII PF16471.5 EMR64677.1 - 0.0024 18.0 56.9 0.023 14.9 2.4 10.4 7 2 4 11 11 11 4 JNK-interacting protein leucine zipper II DHR10 PF18595.1 EMR64677.1 - 0.0047 17.0 3.7 0.0047 17.0 3.7 8.7 2 2 7 9 9 8 1 Designed helical repeat protein 10 domain XhlA PF10779.9 EMR64677.1 - 0.0052 17.0 33.9 0.76 10.0 0.2 8.7 7 1 1 8 8 8 1 Haemolysin XhlA Spc7 PF08317.11 EMR64677.1 - 0.0062 15.5 17.5 0.0062 15.5 17.5 5.5 2 1 2 5 5 5 3 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 EMR64677.1 - 0.0087 16.3 8.0 0.0087 16.3 8.0 7.3 2 2 4 6 6 6 1 JNK_SAPK-associated protein-1 Bacillus_HBL PF05791.11 EMR64677.1 - 0.013 15.3 4.0 0.013 15.3 4.0 6.5 4 2 4 8 8 8 0 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.11 EMR64677.1 - 0.018 15.3 6.4 0.018 15.3 6.4 7.2 1 1 4 6 6 5 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.6 EMR64677.1 - 0.021 14.9 2.1 0.021 14.9 2.1 9.8 5 2 5 12 12 9 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 EMR64677.1 - 0.023 14.8 48.8 0.96 9.5 1.3 7.4 5 1 2 7 7 7 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EMR64677.1 - 0.051 12.9 67.4 0.028 13.8 10.6 5.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) DUF2353 PF09789.9 EMR64677.1 - 0.076 12.4 63.9 0.048 13.0 8.5 4.8 2 1 2 4 4 3 0 Uncharacterized coiled-coil protein (DUF2353) NPV_P10 PF05531.12 EMR64677.1 - 0.26 11.8 0.2 0.26 11.8 0.2 7.8 6 3 1 9 9 9 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 EMR64677.1 - 0.31 10.4 83.7 0.084 12.2 10.2 6.2 2 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding WD40_alt PF14077.6 EMR64677.1 - 0.42 10.5 4.8 2.3 8.1 0.4 4.3 3 1 0 3 3 3 0 Alternative WD40 repeat motif MAD PF05557.13 EMR64677.1 - 1.9 6.8 80.3 1.1 7.6 7.2 4.9 2 1 3 5 5 5 0 Mitotic checkpoint protein Atg14 PF10186.9 EMR64677.1 - 2 7.5 67.9 1.2 8.1 13.9 5.4 1 1 4 5 5 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 DHDPS PF00701.22 EMR64678.1 - 3.6e-33 114.5 0.0 6.4e-16 57.9 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family Acetyltransf_2 PF00797.17 EMR64679.1 - 1.6e-41 142.7 3.0 1.9e-36 126.1 1.3 3.0 2 1 0 2 2 2 2 N-acetyltransferase Peptidase_C71 PF12386.8 EMR64679.1 - 0.033 13.9 0.1 0.086 12.5 0.1 1.6 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei eIF3_N PF09440.10 EMR64680.1 - 3.6e-45 153.7 1.6 3.6e-45 153.7 1.6 1.8 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EMR64680.1 - 6.7e-12 45.8 0.5 1.7e-11 44.6 0.1 1.9 2 0 0 2 2 2 1 PCI domain Sipho_Gp157 PF05565.11 EMR64680.1 - 0.029 14.4 0.2 0.052 13.5 0.2 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 DDRGK PF09756.9 EMR64680.1 - 0.04 13.5 0.7 0.66 9.5 0.1 2.5 2 0 0 2 2 2 0 DDRGK domain Glyco_hydro_5_C PF18564.1 EMR64681.1 - 3.2e-20 72.4 0.0 7.1e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain FAD_binding_4 PF01565.23 EMR64682.1 - 3.9e-20 72.0 0.5 7.2e-20 71.1 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR64682.1 - 4.8e-13 49.0 0.2 9.6e-13 48.0 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EMR64682.1 - 0.037 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Methyltransf_2 PF00891.18 EMR64683.1 - 1.3e-23 83.4 0.0 2.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EMR64683.1 - 0.0023 18.6 0.0 0.0086 16.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EMR64683.1 - 0.12 11.8 0.0 0.47 9.9 0.0 1.9 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain NmrA PF05368.13 EMR64684.1 - 3.4e-15 56.2 0.0 4.7e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR64684.1 - 1e-10 41.8 0.0 2.1e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR64684.1 - 9.2e-06 25.3 0.1 0.00025 20.6 0.2 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR64684.1 - 0.0078 16.1 0.1 0.017 15.1 0.1 1.6 1 1 1 2 2 2 1 KR domain adh_short PF00106.25 EMR64684.1 - 0.026 14.0 0.1 0.05 13.1 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 EMR64684.1 - 0.17 12.2 0.3 0.29 11.4 0.3 1.3 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_2 PF00891.18 EMR64685.1 - 2.1e-17 63.1 0.0 4.6e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 EMR64685.1 - 0.03 14.3 0.0 0.087 12.8 0.0 1.7 2 0 0 2 2 2 0 Dimerisation domain adh_short PF00106.25 EMR64686.1 - 1.3e-40 138.9 0.0 1.8e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64686.1 - 3.7e-29 101.9 0.0 4.6e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64686.1 - 0.00035 20.5 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMR64686.1 - 0.00072 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 EMR64686.1 - 0.0014 17.8 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EMR64686.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EMR64686.1 - 0.027 15.0 0.0 0.051 14.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Tudor_FRX1 PF18336.1 EMR64686.1 - 0.04 13.8 0.7 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain NAD_binding_10 PF13460.6 EMR64686.1 - 0.075 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR64686.1 - 0.08 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CFEM PF05730.11 EMR64687.1 - 5e-14 52.1 10.9 7.2e-14 51.6 10.9 1.2 1 0 0 1 1 1 1 CFEM domain Proteasom_PSMB PF10508.9 EMR64687.1 - 0.33 9.4 0.4 0.45 9.0 0.4 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Trypsin PF00089.26 EMR64688.1 - 0.0077 16.1 0.2 0.08 12.7 0.1 2.0 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 EMR64688.1 - 0.12 13.3 0.2 0.23 12.4 0.2 1.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain 2-Hacid_dh_C PF02826.19 EMR64689.1 - 2.8e-47 160.4 0.1 4.6e-47 159.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR64689.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMR64689.1 - 5.9e-05 23.3 0.0 0.00012 22.2 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HTH_1 PF00126.27 EMR64689.1 - 0.085 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Sugar_tr PF00083.24 EMR64690.1 - 4.6e-77 259.8 18.0 5.2e-77 259.6 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR64690.1 - 9.1e-19 67.6 52.5 1.4e-12 47.2 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_2 PF07719.17 EMR64691.1 - 9e-27 91.0 26.3 0.001 19.0 0.0 14.2 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_1 PF00515.28 EMR64691.1 - 2.6e-24 84.0 20.3 0.00084 19.1 0.0 13.3 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 EMR64691.1 - 1.8e-21 74.5 26.5 0.045 14.0 0.0 14.1 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 EMR64691.1 - 5.9e-19 68.4 16.9 0.025 15.1 0.0 8.6 8 1 1 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 EMR64691.1 - 1.4e-17 64.0 28.4 6.5e-05 23.5 0.7 10.6 9 2 1 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 EMR64691.1 - 2.5e-17 62.9 38.4 0.00058 20.1 0.0 12.5 9 5 4 13 13 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMR64691.1 - 1.5e-15 56.6 22.6 0.037 14.8 0.0 12.5 10 4 4 14 14 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMR64691.1 - 1.8e-15 56.1 9.7 0.026 14.9 0.0 12.1 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMR64691.1 - 9.8e-11 40.9 20.0 0.15 12.2 0.1 11.1 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMR64691.1 - 3.4e-10 39.4 27.6 0.00043 19.9 0.1 9.5 11 0 0 11 11 11 3 TPR repeat TPR_9 PF13371.6 EMR64691.1 - 2e-07 31.0 7.5 0.049 13.8 0.0 6.3 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_22 PF18833.1 EMR64691.1 - 2.8e-05 24.1 0.0 9.9e-05 22.4 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR64691.1 - 5.4e-05 23.3 14.8 0.38 11.0 0.0 8.1 8 0 0 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EMR64691.1 - 0.00012 22.5 30.1 0.17 12.5 0.0 11.7 13 0 0 13 13 10 2 Tetratricopeptide repeat DUF5588 PF17826.1 EMR64691.1 - 0.0016 17.4 1.1 0.36 9.7 0.0 3.6 4 0 0 4 4 4 1 Family of unknown function (DUF5588) TPR_10 PF13374.6 EMR64691.1 - 0.0048 16.7 16.9 16 5.5 0.0 8.9 10 0 0 10 10 8 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EMR64691.1 - 0.0065 15.6 0.0 0.026 13.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region ChAPs PF09295.10 EMR64691.1 - 0.043 12.8 0.3 14 4.6 0.0 3.6 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.12 EMR64691.1 - 0.077 13.0 1.2 95 3.1 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EMR64691.1 - 0.19 11.9 3.3 58 3.9 0.0 4.9 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain RPN6_N PF18055.1 EMR64691.1 - 0.24 11.8 3.3 7.8 6.9 0.0 3.7 4 0 0 4 4 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF2225 PF09986.9 EMR64691.1 - 0.3 10.8 5.7 10 5.8 0.0 4.8 4 2 2 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2225) HemY_N PF07219.13 EMR64691.1 - 2.1 8.6 10.9 21 5.4 0.0 5.4 5 2 2 7 7 6 0 HemY protein N-terminus TPR_4 PF07721.14 EMR64691.1 - 6.7 7.7 17.1 0.81 10.5 0.8 6.0 6 0 0 6 6 4 0 Tetratricopeptide repeat Glyco_hydro_43 PF04616.14 EMR64692.1 - 2.8e-52 177.8 1.4 3.3e-52 177.6 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBS PF00571.28 EMR64693.1 - 3.3e-34 117.1 9.9 8.4e-10 39.0 0.0 5.8 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 EMR64693.1 - 1.1e-08 34.9 0.4 2.7e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 PB1 domain Pkinase PF00069.25 EMR64694.1 - 9.7e-58 195.6 0.0 1.3e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64694.1 - 1.8e-42 145.5 0.0 2.5e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR64694.1 - 3.7e-08 33.0 0.0 2.7e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMR64694.1 - 0.0027 16.6 0.1 0.0039 16.0 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EMR64694.1 - 0.0033 16.8 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR64694.1 - 0.042 13.8 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1843 PF08898.10 EMR64694.1 - 0.13 12.8 0.1 4.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Sulfate_transp PF00916.20 EMR64695.1 - 1.5e-107 359.7 21.2 2.1e-107 359.2 21.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMR64695.1 - 4.9e-09 35.8 0.0 9.9e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EMR64695.1 - 0.00041 20.7 4.6 0.00041 20.7 4.6 3.5 2 2 1 3 3 3 1 Molybdate transporter of MFS superfamily YdjM PF04307.14 EMR64695.1 - 0.012 14.9 0.0 0.073 12.4 0.0 2.3 1 1 1 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase Epimerase PF01370.21 EMR64696.1 - 2.7e-20 72.8 0.0 3.6e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR64696.1 - 1.6e-11 43.8 0.0 2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMR64696.1 - 2e-11 43.9 0.0 2.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMR64696.1 - 0.00012 21.3 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EMR64696.1 - 0.00029 20.1 0.1 0.12 11.6 0.1 2.5 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 EMR64696.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EMR64696.1 - 0.0027 17.7 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR64696.1 - 0.0033 17.3 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR64696.1 - 0.0056 16.3 0.0 0.039 13.5 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EMR64696.1 - 0.008 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EMR64696.1 - 0.0099 15.0 0.0 0.078 12.1 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 EMR64696.1 - 0.041 14.0 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain zf-MYND PF01753.18 EMR64697.1 - 1.6e-09 37.7 15.3 3.3e-09 36.7 15.3 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EMR64697.1 - 0.17 12.2 11.6 0.35 11.2 11.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ribosomal_S2 PF00318.20 EMR64698.1 - 2.9e-63 213.0 0.1 3.4e-62 209.5 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 Bac_DNA_binding PF00216.21 EMR64698.1 - 0.1 12.8 0.3 0.23 11.7 0.3 1.5 1 0 0 1 1 1 0 Bacterial DNA-binding protein Aldo_ket_red PF00248.21 EMR64699.1 - 3.2e-66 223.5 0.0 4.2e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TRI9 PF08195.11 EMR64699.1 - 0.043 13.7 0.2 0.076 12.9 0.2 1.4 1 0 0 1 1 1 0 TRI9 protein zf-C2H2 PF00096.26 EMR64700.1 - 3.6e-11 42.9 17.4 3.6e-05 24.0 4.9 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMR64700.1 - 1.6e-06 28.2 16.3 0.00066 20.0 1.5 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMR64700.1 - 2.1e-06 28.0 15.8 0.016 16.0 3.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EMR64700.1 - 0.023 14.5 5.8 0.15 11.9 1.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 EMR64700.1 - 1 9.9 7.1 5.8 7.4 2.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EMR64700.1 - 1.5 8.9 11.9 2.4 8.2 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.12 EMR64700.1 - 7.2 6.9 8.5 17 5.7 8.5 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain BNR_2 PF13088.6 EMR64701.1 - 9.6e-13 48.1 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 EMR64701.1 - 0.1 12.7 0.3 0.25 11.5 0.3 1.7 1 0 0 1 1 1 0 BNR/Asp-box repeat Fringe PF02434.16 EMR64702.1 - 2.3e-07 30.5 0.0 9.5e-05 21.9 0.1 3.0 2 1 0 2 2 2 1 Fringe-like Dimerisation2 PF16864.5 EMR64702.1 - 0.0015 18.4 0.1 0.0034 17.3 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain PAN_4 PF14295.6 EMR64702.1 - 0.029 14.3 0.6 0.073 13.0 0.6 1.6 1 0 0 1 1 1 0 PAN domain Dimerisation PF08100.11 EMR64702.1 - 0.044 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_2 PF00891.18 EMR64702.1 - 0.067 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Put_DNA-bind_N PF06971.13 EMR64702.1 - 0.082 12.9 0.4 0.27 11.3 0.0 2.1 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus FMN_dh PF01070.18 EMR64703.1 - 8.1e-98 327.6 0.0 9.2e-98 327.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EMR64703.1 - 0.00016 21.0 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EMR64703.1 - 0.0011 18.1 0.0 0.0025 16.8 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain GST_C PF00043.25 EMR64704.1 - 2.1e-16 59.9 0.0 4.6e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMR64704.1 - 2.5e-14 53.4 0.2 1.5e-13 50.9 0.1 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR64704.1 - 1.1e-12 48.1 0.1 2e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR64704.1 - 5.3e-12 45.8 0.0 2.3e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR64704.1 - 3.3e-09 36.9 0.1 7.7e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR64704.1 - 1.2e-07 31.6 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EMR64704.1 - 0.024 15.4 0.0 0.042 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EMR64704.1 - 0.033 14.5 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein FadA PF09403.10 EMR64705.1 - 0.022 15.2 2.7 0.022 15.2 2.7 6.7 3 2 2 6 6 6 0 Adhesion protein FadA Takusan PF04822.13 EMR64705.1 - 0.035 14.0 22.8 0.66 9.9 1.7 5.6 5 1 1 6 6 6 0 Takusan MinE PF03776.14 EMR64705.1 - 0.067 13.2 4.2 6.1 6.9 0.1 3.2 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE DNA_primase_lrg PF04104.14 EMR64705.1 - 0.079 12.4 0.0 0.079 12.4 0.0 4.5 2 1 1 5 5 5 0 Eukaryotic and archaeal DNA primase, large subunit Minor_capsid_3 PF12691.7 EMR64705.1 - 0.096 13.1 4.0 0.87 10.0 0.6 2.9 2 0 0 2 2 2 0 Minor capsid protein from bacteriophage TMF_TATA_bd PF12325.8 EMR64705.1 - 0.12 12.6 64.7 0.23 11.7 14.9 6.7 5 1 3 8 8 8 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 EMR64705.1 - 0.62 9.6 56.7 0.46 10.0 3.7 3.8 2 2 1 3 3 3 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 EMR64705.1 - 1.7 8.6 70.0 0.39 10.7 2.5 6.2 3 2 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 EMR64705.1 - 3.7 6.9 68.6 0.3 10.5 21.0 5.1 2 2 1 4 4 4 0 Hyaluronan mediated motility receptor N-terminal Amidase PF01425.21 EMR64706.1 - 2.4e-74 250.9 8.3 4.8e-36 124.7 0.1 3.7 3 2 0 3 3 3 3 Amidase TetR_C_31 PF17940.1 EMR64706.1 - 0.91 9.8 15.9 0.37 11.0 1.3 3.6 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Sec10 PF07393.11 EMR64708.1 - 2.4e-217 723.8 0.2 2.8e-217 723.6 0.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 BssS PF13991.6 EMR64708.1 - 0.068 13.3 1.1 0.43 10.7 0.0 2.9 3 1 1 4 4 4 0 BssS protein family Cupin_8 PF13621.6 EMR64709.1 - 1.3e-30 106.9 0.0 2.7e-30 105.9 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EMR64709.1 - 7e-11 42.1 0.0 4.2e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 EMR64709.1 - 0.00021 21.7 0.0 0.0079 16.6 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EMR64709.1 - 0.0089 15.7 0.0 0.053 13.2 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Lactonase PF10282.9 EMR64711.1 - 0.00072 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Methyltransf_2 PF00891.18 EMR64712.1 - 1.3e-19 70.4 0.0 1.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HTH_10 PF04967.12 EMR64712.1 - 0.095 12.5 0.5 0.49 10.2 0.2 2.1 1 1 1 2 2 2 0 HTH DNA binding domain adh_short PF00106.25 EMR64713.1 - 4.8e-27 94.7 0.0 1.2e-25 90.1 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64713.1 - 1.1e-21 77.5 0.0 3.4e-20 72.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR64713.1 - 0.00096 18.7 0.1 0.006 16.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR64713.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EMR64713.1 - 0.0071 16.1 0.1 0.03 14.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Acyl-CoA_dh_N PF02771.16 EMR64713.1 - 0.14 12.9 0.1 0.39 11.4 0.1 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain APS_kinase PF01583.20 EMR64713.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase EHN PF06441.12 EMR64714.1 - 1.9e-28 99.0 0.3 4.1e-28 97.9 0.1 1.6 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMR64714.1 - 4.1e-08 33.2 0.0 6.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR64714.1 - 0.027 15.1 0.5 0.046 14.3 0.5 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.25 EMR64715.1 - 8.5e-34 116.7 2.4 1e-33 116.4 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64715.1 - 7.1e-25 87.9 1.6 1.2e-24 87.2 1.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64715.1 - 1.7e-14 54.2 1.6 2.3e-14 53.7 1.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR64715.1 - 1.1e-05 25.0 0.2 7.3e-05 22.3 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMR64715.1 - 0.011 14.9 0.2 0.013 14.6 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMR64715.1 - 0.058 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EMR64715.1 - 0.24 11.4 1.0 1.2 9.3 0.2 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amidase PF01425.21 EMR64716.1 - 4.1e-69 233.7 0.1 3.3e-52 178.0 0.0 3.2 2 1 1 3 3 3 3 Amidase Proho_convert PF12177.8 EMR64716.1 - 0.099 12.6 0.0 0.36 10.8 0.0 2.0 1 0 0 1 1 1 0 Prohormone convertase enzyme Fumble PF03630.14 EMR64717.1 - 2.4e-142 474.0 0.0 3.3e-142 473.5 0.0 1.1 1 0 0 1 1 1 1 Fumble Ran_BP1 PF00638.18 EMR64718.1 - 1e-50 171.1 0.3 1.8e-50 170.3 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EMR64718.1 - 0.0018 18.2 0.0 0.0071 16.3 0.0 1.8 1 1 0 1 1 1 1 WH1 domain CDC27 PF09507.10 EMR64718.1 - 9.3 5.5 20.6 0.19 11.1 12.3 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Phosducin PF02114.16 EMR64721.1 - 1.3e-11 44.0 0.1 4.7e-10 38.9 0.0 2.3 1 1 1 2 2 2 2 Phosducin Herpes_UL32 PF06070.11 EMR64721.1 - 0.019 12.7 1.3 0.029 12.1 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Nup188_C PF18378.1 EMR64722.1 - 4.2e-146 486.5 0.0 9.7e-146 485.3 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EMR64722.1 - 5.4e-11 41.2 4.9 5.3e-05 21.4 0.2 3.6 3 0 0 3 3 3 3 Nucleoporin subcomplex protein binding to Pom34 DUF4211 PF13926.6 EMR64723.1 - 6.6e-44 149.5 0.0 6.6e-44 149.5 0.0 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4211) L51_S25_CI-B8 PF05047.16 EMR64724.1 - 6.7e-15 54.7 0.1 9.6e-15 54.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 EMR64725.1 - 5.6e-24 84.6 2.8 1.2e-23 83.6 2.8 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EMR64725.1 - 1.9e-09 37.2 0.1 1.3e-08 34.5 0.1 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR64725.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Ribosomal_L10 PF00466.20 EMR64726.1 - 1.9e-21 76.1 0.0 2.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EMR64726.1 - 4e-18 65.2 0.0 6.4e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P zf-Tim10_DDP PF02953.15 EMR64727.1 - 1.4e-19 69.5 3.2 1.4e-19 69.5 3.2 1.6 2 0 0 2 2 2 1 Tim10/DDP family zinc finger IGPS PF00218.21 EMR64728.1 - 8.8e-95 316.7 0.0 1.3e-94 316.1 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 EMR64728.1 - 9.1e-47 159.3 0.0 1.8e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 EMR64728.1 - 1.6e-40 139.0 0.0 6e-36 124.1 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 EMR64728.1 - 0.00014 21.7 0.2 0.00049 19.9 0.2 1.8 1 1 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.18 EMR64728.1 - 0.038 13.0 1.3 0.087 11.8 0.1 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase QRPTase_C PF01729.19 EMR64728.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.5 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain TIM PF00121.18 EMR64729.1 - 1.4e-86 289.9 0.3 1.6e-86 289.7 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 EMR64729.1 - 0.027 13.9 0.0 0.054 13.0 0.0 1.4 1 1 0 1 1 1 0 CutC family DLIC PF05783.11 EMR64730.1 - 3.1e-20 72.5 0.0 1.4e-17 63.7 0.0 2.3 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) MF_alpha_N PF05436.11 EMR64731.1 - 0.049 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus FAD_binding_7 PF03441.14 EMR64732.1 - 4.4e-46 156.9 0.6 7.2e-46 156.2 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EMR64732.1 - 4.7e-06 26.7 0.0 8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase FPP PF05911.11 EMR64733.1 - 0.14 10.3 30.5 0.011 14.0 1.6 3.2 3 0 0 3 3 3 0 Filament-like plant protein, long coiled-coil DUF4200 PF13863.6 EMR64733.1 - 5.3 7.5 15.8 0.28 11.6 4.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.6 EMR64733.1 - 8.7 5.6 21.9 1.3 8.3 6.8 3.5 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding Thioredox_DsbH PF03190.15 EMR64734.1 - 2.3e-55 187.0 0.0 4e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EMR64734.1 - 1.7e-05 24.9 0.0 4.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_76 PF03663.14 EMR64734.1 - 0.0036 16.9 2.1 0.051 13.1 2.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 EMR64734.1 - 0.04 12.4 0.2 0.071 11.6 0.2 1.3 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Mucin PF01456.17 EMR64734.1 - 9.8 6.2 25.1 7.2 6.6 12.9 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein TRAM_LAG1_CLN8 PF03798.16 EMR64736.1 - 8.5e-36 123.5 15.4 1.4e-35 122.8 15.4 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EMR64736.1 - 1.8e-20 72.3 0.5 5.8e-20 70.7 0.5 1.9 1 0 0 1 1 1 1 TRAM1-like protein RelA_SpoT PF04607.17 EMR64737.1 - 2.7e-09 37.3 0.0 7.1e-09 36.0 0.0 1.7 2 1 0 2 2 2 1 Region found in RelA / SpoT proteins DUF550 PF04447.12 EMR64737.1 - 0.058 13.5 0.1 0.27 11.4 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF550) Peptidase_S10 PF00450.22 EMR64738.1 - 8.4e-74 249.4 0.0 1.2e-73 248.9 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase RRM_1 PF00076.22 EMR64739.1 - 2.4e-13 49.7 0.0 2.3e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR64739.1 - 0.039 14.1 0.0 0.099 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Bax1-I PF01027.20 EMR64740.1 - 3.1e-53 180.7 24.3 3.6e-53 180.5 24.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Septin PF00735.18 EMR64741.1 - 6.3e-109 363.6 0.1 1.3e-108 362.6 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EMR64741.1 - 9.1e-05 22.5 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EMR64741.1 - 0.0035 17.4 2.9 1.8 8.6 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AAA_23 PF13476.6 EMR64741.1 - 0.0059 17.1 2.7 2.1 8.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EMR64741.1 - 0.013 15.5 0.3 0.013 15.5 0.3 2.3 3 1 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 EMR64741.1 - 0.029 13.9 0.9 0.11 12.1 0.1 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EMR64741.1 - 0.052 13.8 0.8 0.15 12.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMR64741.1 - 0.06 13.5 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain EB1 PF03271.17 EMR64741.1 - 0.18 12.1 1.7 5.5 7.3 1.1 2.7 2 0 0 2 2 2 0 EB1-like C-terminal motif Roc PF08477.13 EMR64741.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EMR64741.1 - 0.21 10.9 0.1 0.21 10.9 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family zf-C2H2 PF00096.26 EMR64742.1 - 1.4e-08 34.7 19.4 0.013 15.9 2.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR64742.1 - 3.7e-07 30.4 14.5 0.021 15.6 2.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 EMR64742.1 - 0.073 13.7 1.4 0.073 13.7 1.4 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 EMR64742.1 - 0.39 11.2 26.8 1.6 9.3 2.0 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-HYPF PF07503.12 EMR64742.1 - 0.59 10.0 4.4 1.4 8.7 4.4 1.6 1 0 0 1 1 1 0 HypF finger Sina PF03145.16 EMR64742.1 - 1.9 8.4 12.7 6.5 6.6 9.9 2.1 1 1 1 2 2 2 0 Seven in absentia protein family PX PF00787.24 EMR64744.1 - 1.9e-19 69.7 0.2 4e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EMR64744.1 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PH PF00169.29 EMR64745.1 - 1.2e-10 41.9 0.1 1e-09 38.8 0.0 2.4 2 1 0 2 2 2 1 PH domain PH_11 PF15413.6 EMR64745.1 - 4.4e-05 23.8 0.0 0.0001 22.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EMR64745.1 - 0.0015 18.7 0.0 0.0066 16.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3409 PF11889.8 EMR64745.1 - 0.064 13.2 0.6 0.18 11.8 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) zf-MIZ PF02891.20 EMR64746.1 - 1.1e-09 37.9 6.2 4.4e-08 32.8 0.1 2.3 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EMR64746.1 - 0.00027 20.7 0.8 0.00082 19.1 0.8 1.8 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Peptidase_S10 PF00450.22 EMR64747.1 - 5.6e-114 381.8 0.1 6.8e-114 381.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase p450 PF00067.22 EMR64748.1 - 1.8e-29 102.8 0.0 2.1e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 EMR64749.1 - 8.1e-14 51.6 3.3 6e-12 45.5 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 EMR64749.1 - 0.00022 20.3 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EMR64749.1 - 0.00065 19.9 0.2 0.0056 16.9 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR64749.1 - 0.014 14.6 0.7 0.035 13.3 0.1 1.7 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR64749.1 - 0.016 15.2 1.2 0.067 13.2 0.1 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EMR64749.1 - 0.019 13.8 0.2 2 7.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 EMR64749.1 - 0.081 12.5 0.9 0.22 11.1 0.4 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR64749.1 - 0.1 13.2 0.0 0.32 11.6 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 EMR64750.1 - 8.2e-10 38.9 0.1 9.7e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR64750.1 - 7.2e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMR64750.1 - 6.2e-05 22.3 0.0 0.024 13.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EMR64750.1 - 0.00014 21.0 0.0 0.00035 19.7 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EMR64750.1 - 0.0045 17.1 0.1 0.012 15.8 0.1 1.8 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EMR64750.1 - 0.026 14.1 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EMR64750.1 - 0.096 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain But2 PF09792.9 EMR64751.1 - 0.022 15.1 0.1 0.046 14.1 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain PhyH PF05721.13 EMR64752.1 - 7e-12 46.0 0.0 9.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DNA_pol_A_exo1 PF01612.20 EMR64753.1 - 1.4e-09 38.0 0.0 5.7e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Pyr_redox_2 PF07992.14 EMR64754.1 - 2.4e-15 56.6 0.1 6.2e-09 35.5 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR64754.1 - 6.8e-07 29.2 0.7 9.2e-06 25.5 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR64754.1 - 5.3e-06 26.5 0.1 0.059 13.4 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EMR64754.1 - 4.8e-05 22.6 0.0 0.0001 21.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR64754.1 - 7.4e-05 22.9 0.1 0.00014 22.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMR64754.1 - 8.7e-05 21.4 0.1 0.00038 19.3 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EMR64754.1 - 0.00016 20.9 0.1 0.01 15.0 0.0 2.3 1 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMR64754.1 - 0.00032 20.1 0.1 0.0021 17.4 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR64754.1 - 0.00048 19.5 0.1 0.00071 18.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EMR64754.1 - 0.0025 17.2 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR64754.1 - 0.0054 16.0 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EMR64754.1 - 0.024 13.5 0.2 1.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EMR64754.1 - 0.025 13.6 0.1 0.096 11.7 0.1 2.1 2 1 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EMR64754.1 - 0.028 13.7 0.0 0.062 12.6 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RCC1 PF00415.18 EMR64755.1 - 4.5e-49 164.9 19.9 1e-09 38.9 0.0 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMR64755.1 - 2.5e-30 103.6 34.8 2.2e-08 33.7 1.7 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_76 PF03663.14 EMR64756.1 - 1.8e-151 504.9 12.6 2e-151 504.6 12.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMR64756.1 - 0.00073 18.7 6.7 0.025 13.7 0.1 2.9 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Pkinase PF00069.25 EMR64757.1 - 0.14 11.5 0.0 16 4.7 0.0 2.3 2 1 0 2 2 2 0 Protein kinase domain adh_short PF00106.25 EMR64758.1 - 1.4e-16 60.5 0.0 4.7e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64758.1 - 1.4e-06 28.1 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64758.1 - 2.1e-06 27.7 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 EMR64759.1 - 2e-20 73.0 11.8 5.4e-20 71.6 11.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3995 PF13160.6 EMR64759.1 - 0.037 14.4 6.6 0.96 9.8 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3995) DUF1430 PF07242.11 EMR64759.1 - 0.14 12.5 0.7 2.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF3784 PF12650.7 EMR64759.1 - 0.33 11.2 8.3 6.9 6.9 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Phage_holin_5_1 PF06946.11 EMR64759.1 - 0.49 10.8 2.8 0.62 10.5 0.2 2.3 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 DUF998 PF06197.13 EMR64759.1 - 0.55 9.8 9.1 5.7 6.5 9.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Peptidase_S15 PF02129.18 EMR64760.1 - 2.4e-38 132.3 5.0 4.9e-36 124.7 0.5 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EMR64760.1 - 1.1e-18 68.1 0.0 2.5e-18 66.9 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Pyr_redox_2 PF07992.14 EMR64761.1 - 2.1e-05 23.9 0.0 2.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR64761.1 - 0.00041 19.7 0.1 0.00054 19.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR64761.1 - 0.0009 18.9 0.0 0.00096 18.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR64761.1 - 0.003 16.7 0.1 0.0038 16.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR64761.1 - 0.003 16.7 0.2 0.0039 16.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR64761.1 - 0.0066 16.7 0.3 0.014 15.6 0.1 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR64761.1 - 0.0071 15.6 0.0 0.0099 15.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EMR64761.1 - 0.047 12.4 0.1 0.065 11.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EMR64761.1 - 0.074 13.0 1.1 0.13 12.2 0.5 1.7 1 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMR64761.1 - 0.1 11.8 0.5 0.16 11.2 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR64761.1 - 0.11 11.3 0.5 0.16 10.8 0.2 1.4 2 0 0 2 2 2 0 Tryptophan halogenase ComC PF03047.14 EMR64761.1 - 0.48 10.3 0.1 0.48 10.3 0.1 1.8 2 0 0 2 2 2 0 COMC family Ank_2 PF12796.7 EMR64762.1 - 0.027 15.0 0.0 0.18 12.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) HcyBio PF01837.16 EMR64763.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation Y_phosphatase2 PF03162.13 EMR64764.1 - 3.8e-45 153.4 0.0 4.8e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EMR64764.1 - 1.6e-10 41.3 0.0 2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EMR64764.1 - 0.0006 19.6 0.0 0.00084 19.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMR64764.1 - 0.0013 18.3 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DAO PF01266.24 EMR64765.1 - 3.4e-20 72.9 0.0 4e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glyoxalase PF00903.25 EMR64767.1 - 2.1e-10 40.8 0.0 6.3e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMR64767.1 - 5.8e-07 29.8 0.0 0.00025 21.3 0.0 1.9 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ECSIT PF06239.11 EMR64767.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway TxDE PF18711.1 EMR64767.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme OPT PF03169.15 EMR64771.1 - 6.6e-124 414.8 32.7 1.8e-123 413.4 32.7 1.6 1 1 0 1 1 1 1 OPT oligopeptide transporter protein IF2_N PF04760.15 EMR64771.1 - 0.17 11.7 0.3 0.48 10.3 0.3 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region RNA_pol_3_Rpc31 PF11705.8 EMR64772.1 - 0.11 12.8 18.1 0.14 12.4 9.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 COPI_C PF06957.11 EMR64772.1 - 0.75 8.5 9.8 1.5 7.5 9.8 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Ribosomal_60s PF00428.19 EMR64772.1 - 3 8.5 12.1 8.8 7.0 11.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein FYDLN_acid PF09538.10 EMR64772.1 - 5.2 7.8 23.6 2.2 9.0 1.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) Zip PF02535.22 EMR64772.1 - 5.6 6.1 5.6 8.8 5.4 5.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.9 EMR64772.1 - 9.9 6.2 19.5 3.8 7.6 11.7 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Tannase PF07519.11 EMR64774.1 - 0.0011 18.0 0.9 0.11 11.4 0.0 2.3 2 0 0 2 2 2 2 Tannase and feruloyl esterase PKD PF00801.20 EMR64774.1 - 0.0036 17.1 0.7 0.0036 17.1 0.7 2.0 2 0 0 2 2 2 1 PKD domain zf-C4H2 PF10146.9 EMR64776.1 - 0.0088 16.4 4.3 0.0088 16.4 4.3 2.2 1 1 0 2 2 2 1 Zinc finger-containing protein Atg14 PF10186.9 EMR64776.1 - 0.082 12.0 6.5 0.14 11.2 6.5 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DsrH PF04077.12 EMR64776.1 - 0.17 12.1 0.8 0.47 10.6 0.2 2.1 2 0 0 2 2 2 0 DsrH like protein Psu PF07455.11 EMR64777.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) XdhC_C PF13478.6 EMR64777.1 - 0.15 12.6 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain GMC_oxred_N PF00732.19 EMR64778.1 - 4.8e-55 187.0 0.0 6.9e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR64778.1 - 4.3e-29 101.9 0.0 2.3e-28 99.5 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 EMR64778.1 - 3.8e-07 30.0 0.1 6.5e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR64778.1 - 6.9e-06 25.3 0.0 1.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMR64778.1 - 2.1e-05 24.7 0.0 6.2e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR64778.1 - 0.00011 21.6 0.0 0.0086 15.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR64778.1 - 0.0018 17.4 0.3 0.092 11.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EMR64778.1 - 0.0021 17.3 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EMR64778.1 - 0.11 11.2 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EMR64778.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Big_4 PF07532.11 EMR64779.1 - 0.03 14.1 0.7 0.049 13.4 0.7 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) CitMHS PF03600.16 EMR64780.1 - 7.6 5.6 11.8 0.93 8.6 2.5 2.2 2 0 0 2 2 2 0 Citrate transporter DNA_pol_A_exo1 PF01612.20 EMR64781.1 - 1.5e-39 135.5 0.2 3.1e-39 134.5 0.2 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EMR64781.1 - 5.5e-27 94.3 2.7 2.7e-26 92.1 2.7 2.3 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 EMR64781.1 - 5.5e-12 45.5 0.0 1.6e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 HRDC domain NARP1 PF12569.8 EMR64781.1 - 6.8 5.5 17.0 12 4.7 17.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CrgA PF06781.12 EMR64782.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Cell division protein CrgA Abhydrolase_1 PF00561.20 EMR64783.1 - 3.1e-12 46.7 0.2 4.5e-12 46.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR64783.1 - 2.7e-11 44.5 0.1 3.2e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR64783.1 - 3.2e-08 33.1 0.0 4.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMR64783.1 - 4.3e-05 23.8 0.0 6.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Palm_thioest PF02089.15 EMR64783.1 - 0.03 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 EMR64783.1 - 0.087 12.6 0.2 3.1 7.5 0.1 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3237 PF11578.8 EMR64784.1 - 5.5e-13 49.0 0.0 6.4e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) CdhD PF03599.16 EMR64784.1 - 0.16 10.6 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit DAO PF01266.24 EMR64785.1 - 3.3e-07 30.2 0.5 3.5e-05 23.5 0.3 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 EMR64785.1 - 2.6e-06 27.1 0.0 2.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EMR64785.1 - 4.8e-05 22.7 0.3 0.00027 20.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR64785.1 - 5.9e-05 22.3 0.6 0.00011 21.4 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EMR64785.1 - 6.5e-05 22.1 0.1 0.0001 21.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMR64785.1 - 0.00042 20.5 1.0 0.00081 19.6 1.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR64785.1 - 0.0054 16.0 0.2 0.013 14.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR64785.1 - 0.0063 15.4 0.3 0.0071 15.3 0.3 1.1 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 EMR64785.1 - 0.015 14.1 0.1 0.015 14.1 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EMR64785.1 - 0.015 14.5 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EMR64785.1 - 0.071 13.1 0.2 0.071 13.1 0.2 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Inositol_P PF00459.25 EMR64786.1 - 4.5e-63 213.3 0.2 5.5e-63 213.0 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family ADH_N PF08240.12 EMR64787.1 - 2.3e-24 85.3 4.7 2.3e-24 85.3 4.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR64787.1 - 1.2e-15 57.7 0.1 1.9e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR64787.1 - 0.00012 21.5 0.5 0.00012 21.5 0.5 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EMR64787.1 - 0.0019 17.7 0.1 0.0027 17.2 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ELFV_dehydrog PF00208.21 EMR64787.1 - 0.0025 17.6 0.1 0.0045 16.7 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 EMR64787.1 - 0.0049 16.2 0.1 0.0076 15.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GTP_EFTU_D2 PF03144.25 EMR64787.1 - 0.0071 16.7 0.2 0.021 15.2 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TrkA_N PF02254.18 EMR64787.1 - 0.17 12.1 0.2 0.46 10.8 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain GMC_oxred_C PF05199.13 EMR64788.1 - 2.8e-34 118.7 0.0 5.9e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR64788.1 - 3e-19 69.5 0.0 4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase UPF0444 PF15475.6 EMR64788.1 - 0.014 15.7 1.9 0.015 15.5 0.5 1.7 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 HHH PF00633.23 EMR64788.1 - 0.12 12.3 0.0 9.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Anp1 PF03452.14 EMR64789.1 - 0.22 10.9 0.6 0.36 10.2 0.6 1.2 1 0 0 1 1 1 0 Anp1 MFS_1 PF07690.16 EMR64790.1 - 1.2e-32 113.2 50.7 1.1e-30 106.7 50.8 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR64790.1 - 1.4e-08 34.1 9.5 1.4e-08 34.1 9.5 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter His_Phos_2 PF00328.22 EMR64791.1 - 6.2e-65 220.0 0.0 7.2e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) VKOR PF07884.14 EMR64791.1 - 0.11 12.6 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Ras PF00071.22 EMR64792.1 - 4.7e-44 149.9 0.0 1.8e-32 112.2 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 EMR64792.1 - 1.2e-22 80.3 0.0 4.4e-12 46.3 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR64792.1 - 2.6e-06 27.0 0.0 0.031 13.7 0.0 2.3 1 1 1 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EMR64792.1 - 0.0054 16.6 0.3 1.5 8.7 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EMR64792.1 - 0.025 14.9 0.3 0.041 14.3 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 EMR64792.1 - 0.031 13.8 0.0 0.063 12.8 0.0 1.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EMR64792.1 - 0.046 14.0 0.0 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EMR64793.1 - 7e-47 159.7 0.0 2.6e-45 154.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EMR64793.1 - 3.6e-34 116.8 14.8 5.2e-34 116.3 1.5 4.0 3 1 0 4 4 3 2 AAA lid domain AAA PF00004.29 EMR64793.1 - 1.3e-27 96.8 0.3 1e-14 55.1 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EMR64793.1 - 1.2e-24 86.1 0.6 6.3e-24 83.9 0.6 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EMR64793.1 - 4.7e-15 55.8 0.2 3.5e-09 36.8 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMR64793.1 - 9.3e-12 45.6 7.1 2.6e-06 27.9 0.0 4.6 4 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 EMR64793.1 - 1.4e-11 44.8 0.0 0.0004 20.7 0.0 4.1 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EMR64793.1 - 6.4e-09 35.7 0.0 3e-05 23.8 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EMR64793.1 - 4.1e-06 26.6 0.0 0.087 12.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EMR64793.1 - 4.5e-06 26.3 0.0 0.016 14.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Clp_N PF02861.20 EMR64793.1 - 5.6e-06 26.4 8.5 0.0021 18.2 0.0 5.1 5 0 0 5 5 4 1 Clp amino terminal domain, pathogenicity island component AAA_14 PF13173.6 EMR64793.1 - 8.6e-06 25.8 0.0 0.14 12.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EMR64793.1 - 8.9e-06 26.3 0.7 0.13 12.8 0.0 3.6 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EMR64793.1 - 1.2e-05 25.6 0.0 0.27 11.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EMR64793.1 - 1.9e-05 24.7 4.2 0.056 13.4 0.1 4.4 4 1 0 4 4 4 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EMR64793.1 - 2.1e-05 24.0 0.1 0.17 11.2 0.0 3.4 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EMR64793.1 - 6.4e-05 23.2 0.8 0.5 10.6 0.0 3.5 3 1 1 4 4 2 2 AAA domain RNA_helicase PF00910.22 EMR64793.1 - 6.7e-05 23.2 0.0 0.56 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_23 PF13476.6 EMR64793.1 - 0.00017 22.2 8.7 0.36 11.3 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 EMR64793.1 - 0.00022 21.0 0.1 0.47 10.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 EMR64793.1 - 0.00026 21.0 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EMR64793.1 - 0.00033 21.0 0.2 0.22 11.8 0.2 3.8 4 1 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 EMR64793.1 - 0.00047 20.1 0.0 0.49 10.3 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 EMR64793.1 - 0.00047 19.9 0.0 1 9.0 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EMR64793.1 - 0.00056 19.8 0.0 3 7.7 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMR64793.1 - 0.00057 19.7 2.0 3.9 7.2 0.8 4.2 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EMR64793.1 - 0.00073 20.1 0.4 1 9.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter T2SSE PF00437.20 EMR64793.1 - 0.0016 17.6 0.1 0.026 13.6 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 EMR64793.1 - 0.0021 17.8 0.0 2 8.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.15 EMR64793.1 - 0.0022 18.0 0.0 0.72 9.8 0.0 3.7 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit Torsin PF06309.11 EMR64793.1 - 0.0031 17.6 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 Torsin NACHT PF05729.12 EMR64793.1 - 0.0066 16.4 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 EMR64793.1 - 0.0068 16.6 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EMR64793.1 - 0.0095 15.9 0.0 0.33 10.9 0.0 3.2 3 0 0 3 3 2 1 NTPase Rad17 PF03215.15 EMR64793.1 - 0.0099 15.8 0.0 4.6 7.1 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EMR64793.1 - 0.011 15.0 0.0 1.2 8.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 EMR64793.1 - 0.015 14.9 0.1 4.4 6.9 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain V_ATPase_I PF01496.19 EMR64793.1 - 0.022 12.7 1.7 0.04 11.8 1.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 EMR64793.1 - 0.045 13.1 10.0 0.12 11.7 10.0 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ran-binding PF05508.11 EMR64793.1 - 0.051 12.5 0.8 0.14 11.1 0.8 1.7 1 0 0 1 1 1 0 RanGTP-binding protein Macoilin PF09726.9 EMR64793.1 - 0.06 11.9 8.9 0.095 11.2 8.9 1.2 1 0 0 1 1 1 0 Macoilin family ATP_bind_1 PF03029.17 EMR64793.1 - 0.11 12.2 0.0 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EMR64793.1 - 0.12 12.1 0.0 7.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Spc7 PF08317.11 EMR64793.1 - 1.3 7.9 12.4 2.8 6.7 12.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 EMR64793.1 - 2.1 7.4 5.8 3.5 6.6 5.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_25 PF13481.6 EMR64793.1 - 7.9 6.0 9.8 6.8 6.2 0.0 3.8 4 1 0 4 4 4 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 EMR64794.1 - 2.8e-07 31.3 0.1 5.4e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Imm75 PF15660.6 EMR64794.1 - 0.1 12.8 0.6 0.1 12.8 0.6 1.8 2 0 0 2 2 2 0 Putative Immunity protein 75 zf-C3HC4_3 PF13920.6 EMR64795.1 - 0.00052 19.8 11.7 0.00089 19.1 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EMR64795.1 - 0.0068 16.3 6.5 0.011 15.6 6.5 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EMR64795.1 - 2.6 8.1 12.7 4 7.5 12.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EMR64795.1 - 4.9 7.1 13.0 8.9 6.3 13.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Peptidase_C50 PF03568.17 EMR64796.1 - 2.2e-158 527.5 0.0 2.6e-158 527.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 EMR64796.1 - 1.6e-07 31.1 0.2 0.00022 20.7 0.0 2.2 2 0 0 2 2 2 2 CHAT domain Mhr1 PF12829.7 EMR64798.1 - 5.9e-31 106.4 0.0 9.3e-31 105.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Sulfotransfer_3 PF13469.6 EMR64799.1 - 0.00022 21.7 0.2 0.0034 17.8 0.0 2.5 2 1 0 2 2 2 1 Sulfotransferase family Fungal_trans PF04082.18 EMR64800.1 - 7.6e-09 35.0 0.0 1.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PI3_PI4_kinase PF00454.27 EMR64801.1 - 1.1e-34 120.3 0.0 1.2e-33 117.0 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 EMR64801.1 - 0.015 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CXCR4_N PF12109.8 EMR64801.1 - 0.029 14.6 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal CBFD_NFYB_HMF PF00808.23 EMR64802.1 - 6.6e-15 55.1 2.1 1.2e-14 54.4 2.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMR64802.1 - 5.3e-05 23.6 0.5 5.3e-05 23.6 0.5 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EMR64802.1 - 0.008 16.2 2.2 0.008 16.2 2.2 1.5 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Phage_T4_gp19 PF06841.12 EMR64802.1 - 0.024 14.5 0.3 0.11 12.3 0.3 1.9 1 1 0 1 1 1 0 T4-like virus tail tube protein gp19 Myc_N PF01056.18 EMR64802.1 - 0.076 12.9 2.3 0.075 12.9 2.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CENP-X PF09415.10 EMR64802.1 - 0.64 10.4 5.8 0.48 10.8 0.4 2.1 1 1 1 2 2 2 0 CENP-S associating Centromere protein X Kri1 PF05178.12 EMR64803.1 - 2.5e-29 101.9 22.7 2.5e-29 101.9 22.7 5.4 6 2 0 6 6 6 1 KRI1-like family Kri1_C PF12936.7 EMR64803.1 - 5.4e-28 97.0 2.2 5.4e-28 97.0 2.2 3.7 3 1 1 4 4 4 1 KRI1-like family C-terminal ParD PF09386.10 EMR64803.1 - 0.0012 19.1 0.0 0.0046 17.3 0.0 2.0 1 0 0 1 1 1 1 Antitoxin ParD DUF5321 PF17254.2 EMR64804.1 - 8e-33 113.1 2.6 9.1e-33 113.0 2.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) FGGY_C PF02782.16 EMR64805.1 - 5.1e-26 91.6 0.0 8.7e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EMR64805.1 - 9.3e-17 61.4 0.0 2.8e-12 46.7 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.21 EMR64805.1 - 1.6e-12 47.6 0.3 7.9e-12 45.3 0.7 1.8 2 0 0 2 2 2 1 Cation efflux family ZT_dimer PF16916.5 EMR64805.1 - 5.3e-05 23.3 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PIG-X PF08320.12 EMR64806.1 - 1.2e-71 241.0 0.0 2.1e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 SnoaL_4 PF13577.6 EMR64807.1 - 4.3e-08 33.3 0.1 6.1e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain FSH1 PF03959.13 EMR64808.1 - 5.5e-23 81.8 0.0 5.6e-22 78.5 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PRIMA1 PF16101.5 EMR64809.1 - 0.57 10.2 1.9 1.5 8.9 1.9 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TPR_14 PF13428.6 EMR64811.1 - 0.00036 21.1 3.9 0.16 12.9 0.1 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMR64811.1 - 0.00067 20.1 0.9 0.28 11.7 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMR64811.1 - 0.0021 18.3 0.4 5.9 7.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR64811.1 - 0.081 13.1 3.9 22 5.5 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMR64811.1 - 0.33 10.7 9.6 3.2 7.5 0.1 4.7 5 0 0 5 5 5 0 TPR repeat TPR_12 PF13424.6 EMR64811.1 - 0.46 10.8 6.8 0.66 10.3 0.8 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMR64811.1 - 1.3 9.0 8.0 41 4.2 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Arrestin_N PF00339.29 EMR64812.1 - 9.5e-14 51.7 0.0 8.3e-13 48.6 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EMR64812.1 - 1.8e-13 51.1 0.0 3.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 EMR64812.1 - 0.055 13.2 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Bcl-2 PF00452.19 EMR64813.1 - 0.74 10.5 3.4 36 5.1 0.6 3.4 1 1 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family HU-CCDC81_euk_1 PF14908.6 EMR64813.1 - 4.5 7.5 5.6 1.7e+02 2.4 0.0 4.4 2 1 2 4 4 4 0 CCDC81 eukaryotic HU domain 1 KRTAP PF11759.8 EMR64813.1 - 6.2 7.4 11.5 3.2e+02 2.0 11.6 2.4 1 1 0 1 1 1 0 Keratin-associated matrix zf-Nse PF11789.8 EMR64814.1 - 4.1e-20 71.4 0.2 7.1e-20 70.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EMR64814.1 - 0.00086 19.3 0.3 0.0016 18.4 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMR64814.1 - 0.0031 17.3 0.1 0.006 16.4 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EMR64814.1 - 0.0098 15.6 0.2 0.019 14.7 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.25 EMR64814.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3584 PF12128.8 EMR64814.1 - 1.6 6.1 19.8 0.012 13.1 11.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 EMR64814.1 - 1.8 8.7 6.6 0.62 10.2 2.8 2.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 EMR64814.1 - 2.9 8.3 7.6 0.91 9.9 3.5 2.1 1 1 1 2 2 2 0 Syntaxin-like protein MR_MLE_C PF13378.6 EMR64815.1 - 3.9e-58 196.6 0.0 6.7e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMR64815.1 - 0.00041 20.5 0.0 0.00085 19.5 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EMR64815.1 - 0.024 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus PH PF00169.29 EMR64816.1 - 9e-06 26.2 0.0 1.6e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.18 EMR64816.1 - 0.019 14.9 1.6 0.042 13.7 0.5 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain PH_17 PF18012.1 EMR64816.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 PH domain KxDL PF10241.9 EMR64816.1 - 0.19 12.0 2.6 28 5.1 0.2 3.7 4 1 0 5 5 5 0 Uncharacterized conserved protein EF_assoc_2 PF08356.12 EMR64817.1 - 9.8e-34 115.2 0.0 1.8e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EMR64817.1 - 1.3e-16 60.6 0.0 1.1e-15 57.6 0.0 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EMR64817.1 - 2.5e-09 37.4 0.0 4.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 EMR64817.1 - 7.8e-05 23.0 0.1 0.00017 21.9 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair MMR_HSR1 PF01926.23 EMR64817.1 - 0.0002 21.4 0.0 0.00097 19.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 EMR64817.1 - 0.0035 16.8 0.0 0.01 15.3 0.0 1.9 1 0 0 1 1 1 1 EF hand AAA_24 PF13479.6 EMR64817.1 - 0.054 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain EF-hand_6 PF13405.6 EMR64817.1 - 0.072 13.1 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_10 PF14788.6 EMR64817.1 - 0.081 12.8 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 EF hand RsgA_GTPase PF03193.16 EMR64817.1 - 0.11 12.4 0.1 4.3 7.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase DUF1772 PF08592.11 EMR64818.1 - 3.1e-05 24.3 3.3 3.3e-05 24.2 2.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) WD40 PF00400.32 EMR64820.1 - 1.2e-06 29.1 0.1 0.0009 20.0 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR64820.1 - 1.5e-05 25.2 0.0 0.035 14.4 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain ECR1_N PF14382.6 EMR64820.1 - 0.03 14.1 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Leptin PF02024.15 EMR64820.1 - 0.098 12.4 0.0 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 Leptin YpsA PF06908.11 EMR64820.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 YspA SLOG family Clr5 PF14420.6 EMR64821.1 - 1.4e-14 54.0 0.3 1.9e-14 53.6 0.3 1.2 1 0 0 1 1 1 1 Clr5 domain AAA PF00004.29 EMR64822.1 - 5.6e-08 33.3 0.0 1.9e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Coilin_N PF15862.5 EMR64822.1 - 0.39 10.5 12.4 2.3 8.0 8.3 2.8 1 1 1 2 2 2 0 Coilin N-terminus DUF908 PF06012.12 EMR64822.1 - 3.9 6.8 6.7 24 4.2 7.7 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) peroxidase PF00141.23 EMR64823.1 - 4.8e-47 160.6 0.0 7e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase adh_short PF00106.25 EMR64824.1 - 1.9e-21 76.4 0.0 4.7e-21 75.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64824.1 - 1.7e-10 40.9 0.0 3.3e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64824.1 - 0.0057 16.6 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Ureide_permease PF07168.11 EMR64824.1 - 0.012 14.4 0.0 0.032 13.0 0.0 1.6 2 0 0 2 2 2 0 Ureide permease NAD_binding_10 PF13460.6 EMR64824.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 EMR64824.1 - 0.099 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EMR64824.1 - 0.14 11.2 0.0 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Acetyltransf_2 PF00797.17 EMR64825.1 - 0.0013 18.6 0.0 0.0015 18.4 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase ADH_zinc_N PF00107.26 EMR64826.1 - 1.3e-12 47.8 0.1 2.2e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR64826.1 - 6.6e-06 26.0 0.1 2.4e-05 24.2 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMR64826.1 - 0.12 13.5 0.0 0.21 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Lon_C PF05362.13 EMR64829.1 - 3.3e-64 216.2 0.0 5.9e-64 215.4 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EMR64829.1 - 1e-29 104.0 0.0 2.4e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EMR64829.1 - 1.3e-21 77.4 0.0 2.9e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EMR64829.1 - 1.8e-07 31.1 0.0 5.2e-07 29.5 0.0 1.8 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EMR64829.1 - 4.1e-07 30.1 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMR64829.1 - 2.7e-06 27.6 0.0 7.8e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EMR64829.1 - 1.9e-05 24.5 0.1 0.00056 19.7 0.0 2.9 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR64829.1 - 3e-05 24.3 0.0 0.00055 20.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 EMR64829.1 - 4.2e-05 22.6 0.0 9e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 EMR64829.1 - 0.00024 21.6 0.1 0.0018 18.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EMR64829.1 - 0.013 16.0 0.6 0.059 13.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMR64829.1 - 0.02 14.9 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.9 EMR64829.1 - 0.022 14.8 0.2 0.022 14.8 0.2 2.6 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein DNTTIP1_dimer PF18192.1 EMR64829.1 - 0.025 14.9 0.6 0.75 10.2 0.4 3.0 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain IstB_IS21 PF01695.17 EMR64829.1 - 0.027 14.2 0.0 0.089 12.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EMR64829.1 - 0.035 14.0 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EMR64829.1 - 0.039 13.7 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR64829.1 - 0.044 14.2 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EMR64829.1 - 0.064 12.8 0.7 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region SKI PF01202.22 EMR64829.1 - 0.099 12.8 0.1 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.15 EMR64829.1 - 0.11 12.4 0.2 1.3 8.9 0.0 2.5 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 EMR64829.1 - 0.51 10.8 4.3 0.71 10.4 0.0 2.7 3 0 0 3 3 2 0 ABC transporter ADH_N PF08240.12 EMR64830.1 - 1.4e-10 41.0 0.0 3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR64830.1 - 3.3e-08 33.6 0.1 6.2e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMR64830.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase MutL_C PF08676.11 EMR64831.1 - 1.2e-18 67.3 2.4 5.3e-17 61.9 1.4 3.1 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EMR64831.1 - 6.6e-13 48.7 0.0 2.9e-12 46.6 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EMR64831.1 - 7e-08 33.0 0.0 2.7e-07 31.1 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 EMR64832.1 - 0.00018 21.0 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CoA_binding_2 PF13380.6 EMR64834.1 - 5.7e-29 101.0 0.0 6.5e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain MFS_1 PF07690.16 EMR64835.1 - 1.3e-34 119.7 19.0 1.6e-34 119.4 19.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR64835.1 - 1.3e-08 33.8 6.9 1.6e-08 33.5 6.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMR64835.1 - 1.8e-08 33.7 9.9 2.3e-08 33.4 9.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EMR64835.1 - 0.00014 21.3 6.5 0.00017 21.0 6.5 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 EMR64835.1 - 0.0061 15.2 3.8 0.0082 14.8 3.8 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 EMR64835.1 - 0.02 13.8 7.7 0.026 13.4 7.7 1.2 1 0 0 1 1 1 0 MFS_1 like family COX2-transmemb PF09125.10 EMR64835.1 - 0.16 11.8 2.3 0.24 11.2 0.3 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane Sugar_tr PF00083.24 EMR64836.1 - 1.1e-55 189.3 9.5 1.4e-55 189.0 9.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR64836.1 - 4.2e-13 49.0 16.1 4.2e-13 49.0 16.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily YwiC PF14256.6 EMR64836.1 - 2.3 8.6 8.7 0.14 12.5 2.4 2.1 2 0 0 2 2 2 0 YwiC-like protein MFS_1 PF07690.16 EMR64837.1 - 2.9e-09 36.3 18.0 2.9e-09 36.3 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EMR64838.1 - 8.6e-49 166.5 0.0 3.5e-48 164.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DLH PF01738.18 EMR64839.1 - 2.9e-21 76.1 0.0 3.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Radical_SAM_N PF08497.10 EMR64839.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal NAD_binding_10 PF13460.6 EMR64839.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 EMR64840.1 - 1.1e-37 129.4 0.0 1.6e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64840.1 - 9e-21 74.5 0.0 1.2e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64840.1 - 3.7e-06 27.0 0.0 7.3e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 KR domain Rnk_N PF14760.6 EMR64840.1 - 0.46 11.0 0.1 0.46 11.0 0.1 2.0 3 0 0 3 3 3 0 Rnk N-terminus Transp_cyt_pur PF02133.15 EMR64841.1 - 6.9e-39 133.8 23.6 6.9e-39 133.8 23.6 1.8 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin SNF5 PF04855.12 EMR64842.1 - 9.3e-90 300.6 0.0 1.2e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EMR64842.1 - 1.8 8.2 8.9 0.14 11.8 3.6 2.0 2 1 0 2 2 2 0 GATA zinc finger Amidase PF01425.21 EMR64843.1 - 9.6e-73 245.7 3.9 4.3e-60 204.0 3.8 2.0 1 1 1 2 2 2 2 Amidase PTE PF02126.18 EMR64843.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family Methyltransf_11 PF08241.12 EMR64844.1 - 7.4e-17 61.8 0.0 2.1e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR64844.1 - 4.6e-15 56.1 0.0 1.9e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR64844.1 - 2e-08 34.9 0.0 6.1e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR64844.1 - 7.1e-07 29.1 0.0 2.2e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR64844.1 - 7e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR64844.1 - 0.00021 20.7 0.0 0.00048 19.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 EMR64844.1 - 0.0088 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 EMR64844.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 EMR64844.1 - 0.26 10.6 0.0 0.95 8.8 0.0 1.9 3 0 0 3 3 3 0 Protein kinase domain Fungal_trans PF04082.18 EMR64845.1 - 3.9e-26 91.7 0.1 5.3e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclin_C PF02984.19 EMR64845.1 - 0.031 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin, C-terminal domain Erg28 PF03694.13 EMR64846.1 - 4.3e-45 152.6 3.7 5.9e-45 152.2 3.7 1.2 1 0 0 1 1 1 1 Erg28 like protein SWIRM PF04433.17 EMR64847.1 - 3e-06 27.5 0.0 1.2e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain SHOCT PF09851.9 EMR64847.1 - 0.042 13.6 1.2 0.16 11.8 1.2 2.1 1 0 0 1 1 1 0 Short C-terminal domain Mt_ATP-synt_D PF05873.12 EMR64847.1 - 2.3 8.0 6.6 2.3 8.1 0.5 2.6 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Rhodanese PF00581.20 EMR64848.1 - 4.7e-10 39.9 0.0 7.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Ribonuc_L-PSP PF01042.21 EMR64849.1 - 1.1e-15 57.7 0.0 1.3e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_C70 PF12385.8 EMR64849.1 - 0.027 14.5 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 GalP_UDP_tr_C PF02744.17 EMR64850.1 - 1.3e-57 194.2 0.0 2e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 EMR64850.1 - 1.7e-32 113.3 0.0 6.4e-31 108.2 0.0 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 EMR64850.1 - 0.00042 21.0 0.0 0.004 17.9 0.0 2.2 2 1 0 2 2 2 1 HIT domain TRAP-gamma PF07074.12 EMR64850.1 - 0.18 11.3 0.0 0.43 10.1 0.0 1.5 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) O-FucT PF10250.9 EMR64852.1 - 8.9e-22 78.2 0.0 2.5e-21 76.7 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Polysacc_deac_1 PF01522.21 EMR64853.1 - 8.8e-11 41.8 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase FMN_dh PF01070.18 EMR64854.1 - 5.3e-76 255.9 3.9 5.7e-49 167.0 0.3 3.0 1 1 2 3 3 3 3 FMN-dependent dehydrogenase IMPDH PF00478.25 EMR64854.1 - 0.00018 20.6 0.3 0.001 18.1 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 EMR64854.1 - 0.00025 20.4 0.1 0.67 9.1 0.0 2.6 2 1 1 3 3 3 2 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 EMR64854.1 - 0.00057 19.1 0.0 0.00083 18.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EMR64854.1 - 0.032 13.7 0.0 2 7.8 0.0 2.6 2 1 0 3 3 3 0 Histidine biosynthesis protein PhyH PF05721.13 EMR64855.1 - 2.3e-12 47.6 0.0 3.6e-12 47.0 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ADH_zinc_N_2 PF13602.6 EMR64856.1 - 1.7e-17 64.7 0.0 7e-17 62.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SBP_bac_6 PF13343.6 EMR64856.1 - 1.3e-13 50.9 0.2 2.3e-13 50.1 0.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein ADH_zinc_N PF00107.26 EMR64856.1 - 2.2e-12 47.1 0.2 9e-12 45.1 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR64856.1 - 1.7e-07 31.1 0.0 2.1e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain SBP_bac_11 PF13531.6 EMR64856.1 - 4.4e-07 29.9 0.1 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein ADH_N_2 PF16884.5 EMR64856.1 - 0.00013 21.8 0.0 0.00053 19.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase SBP_bac_1 PF01547.25 EMR64856.1 - 0.03 14.3 1.2 0.18 11.7 1.2 2.2 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein DHH PF01368.20 EMR64857.1 - 0.0042 17.3 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.19 EMR64857.1 - 0.06 13.8 0.0 0.4 11.1 0.0 2.1 1 1 0 1 1 1 0 DHHA1 domain Nucleoporin_N PF08801.11 EMR64858.1 - 5.1e-75 252.9 0.1 7.7e-75 252.3 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EMR64858.1 - 9.2e-45 153.5 2.1 1.9e-44 152.4 0.9 1.8 1 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF1574 PF07611.11 EMR64858.1 - 0.075 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) RFX_DNA_binding PF02257.15 EMR64859.1 - 0.00069 20.2 0.0 12 6.6 0.0 3.8 1 1 3 4 4 4 2 RFX DNA-binding domain Elongin_A PF06881.11 EMR64859.1 - 0.0053 17.3 9.8 3.9 8.0 3.7 3.5 1 1 2 3 3 3 3 RNA polymerase II transcription factor SIII (Elongin) subunit A Arm_3 PF16186.5 EMR64859.1 - 0.0072 15.9 7.6 13 5.4 0.6 4.0 4 0 0 4 4 4 3 Atypical Arm repeat DUF5613 PF18467.1 EMR64859.1 - 0.1 13.0 1.3 14 6.2 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF5613) DUF3328 PF11807.8 EMR64860.1 - 1.3e-48 165.7 0.1 1.6e-48 165.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_61 PF03443.14 EMR64861.1 - 2.6e-50 171.2 0.1 2.9e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.22 EMR64862.1 - 2.1e-46 158.6 0.0 2.7e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_8 PF13621.6 EMR64864.1 - 1.2e-23 84.1 0.0 3.8e-23 82.5 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EMR64864.1 - 0.00068 19.3 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 EMR64864.1 - 0.0007 20.0 0.0 0.0027 18.1 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 EMR64864.1 - 0.002 17.6 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 EMR64864.1 - 0.062 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin dbPDZ_assoc PF16610.5 EMR64865.1 - 0.06 13.6 0.9 0.06 13.6 0.9 2.1 3 0 0 3 3 3 0 Unstructured region between two PDZ domains on Dlg5 UPF0220 PF05255.11 EMR64867.1 - 1.4e-65 219.9 5.3 1.5e-65 219.8 5.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF5337 PF17272.2 EMR64867.1 - 0.63 9.9 5.1 0.28 11.0 1.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5337) DUF3341 PF11821.8 EMR64867.1 - 1.4 8.5 5.1 0.59 9.8 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Mito_carr PF00153.27 EMR64868.1 - 8.8e-40 134.6 0.4 6.6e-19 67.6 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein SMI1_KNR4 PF09346.10 EMR64869.1 - 2.1e-20 73.5 0.0 4.1e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Aldolase_II PF00596.21 EMR64871.1 - 3.2e-49 167.4 0.1 4e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TES PF08034.11 EMR64871.1 - 0.075 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Trematode eggshell synthesis protein DUF4073 PF13285.6 EMR64871.1 - 0.12 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Urm1 PF09138.11 EMR64872.1 - 4.1e-35 120.0 0.0 4.9e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EMR64872.1 - 0.0015 19.1 0.0 0.0022 18.6 0.0 1.3 1 0 0 1 1 1 1 ThiS family dCMP_cyt_deam_1 PF00383.23 EMR64873.1 - 6.9e-16 58.0 0.2 9.3e-16 57.6 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EMR64873.1 - 2.2e-07 31.1 0.2 3e-07 30.7 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EMR64873.1 - 0.00022 20.9 0.4 0.037 13.6 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sugar_tr PF00083.24 EMR64875.1 - 1.2e-96 324.4 27.0 1.4e-96 324.1 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR64875.1 - 1.6e-20 73.3 19.7 1.6e-20 73.3 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR64875.1 - 0.00031 19.7 6.6 0.069 12.0 3.6 2.6 2 1 0 2 2 2 2 MFS_1 like family DUF3361 PF11841.8 EMR64876.1 - 5.9e-08 32.8 0.0 1.1e-07 32.0 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 EMR64876.1 - 0.0063 17.0 0.2 0.035 14.6 0.1 2.0 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.6 EMR64876.1 - 0.042 14.2 0.1 0.13 12.7 0.0 1.8 2 1 1 3 3 3 0 HEAT repeats HEAT PF02985.22 EMR64876.1 - 0.076 13.3 0.1 0.32 11.4 0.1 2.1 2 1 0 2 2 2 0 HEAT repeat DUF4739 PF15893.5 EMR64876.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4739) Hydrolase_4 PF12146.8 EMR64877.1 - 2.5e-14 53.2 0.0 5.6e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR64877.1 - 1.1e-11 44.9 0.8 1.9e-10 40.8 0.1 2.7 2 1 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR64877.1 - 1.3e-09 39.0 7.8 4.4e-09 37.3 7.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EMR64877.1 - 0.0023 17.5 0.0 0.0093 15.5 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 EMR64877.1 - 0.03 14.0 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.14 EMR64877.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ndr PF03096.14 EMR64877.1 - 0.21 10.2 0.1 3.8 6.1 0.1 2.1 2 0 0 2 2 2 0 Ndr family Abhydrolase_5 PF12695.7 EMR64877.1 - 0.22 11.3 0.0 0.81 9.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family LRS4 PF10422.9 EMR64877.1 - 0.28 10.7 0.1 0.4 10.2 0.1 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 adh_short_C2 PF13561.6 EMR64878.1 - 2.4e-27 96.0 0.0 2.6e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR64878.1 - 2.1e-17 63.2 0.0 2.9e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR64878.1 - 0.053 13.4 0.2 0.091 12.7 0.2 1.3 1 0 0 1 1 1 0 KR domain DUF1772 PF08592.11 EMR64879.1 - 1e-07 32.3 1.0 2.3e-07 31.2 1.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) PfkB PF00294.24 EMR64880.1 - 4.7e-10 39.3 0.4 2.1e-07 30.6 0.2 2.9 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMR64880.1 - 0.079 12.3 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase adh_short_C2 PF13561.6 EMR64881.1 - 2.1e-35 122.4 0.7 3e-35 121.9 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR64881.1 - 2.7e-28 98.8 1.2 3.7e-28 98.3 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR64881.1 - 3.9e-09 36.7 1.2 1.7e-08 34.6 0.2 1.9 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EMR64881.1 - 0.01 15.3 0.0 0.018 14.4 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMR64881.1 - 0.019 14.1 0.1 0.039 13.1 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMR64881.1 - 0.094 12.2 0.0 0.53 9.7 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMR64883.1 - 1.2e-37 129.3 1.6 1.7e-37 128.8 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR64883.1 - 4e-26 92.0 0.1 5.6e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR64883.1 - 4.2e-07 30.1 4.0 7.6e-06 25.9 4.0 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR64883.1 - 4.7e-06 26.2 0.2 1.1e-05 25.0 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR64883.1 - 0.0016 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 EMR64883.1 - 0.006 16.0 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMR64883.1 - 0.0094 15.0 0.2 0.013 14.5 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMR64883.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 EMR64883.1 - 0.049 13.5 1.1 0.11 12.4 1.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EMR64883.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 EMR64883.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3216 PF11505.8 EMR64883.1 - 0.2 11.9 0.0 0.5 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) UDPG_MGDP_dh_N PF03721.14 EMR64883.1 - 0.37 10.4 1.5 0.68 9.5 0.7 1.7 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-GRF PF06839.12 EMR64884.1 - 9.6e-08 32.0 6.9 1.8e-07 31.1 6.9 1.5 1 0 0 1 1 1 1 GRF zinc finger AAA_13 PF13166.6 EMR64884.1 - 0.13 10.9 0.6 0.23 10.0 0.6 1.4 1 0 0 1 1 1 0 AAA domain DUF2505 PF10698.9 EMR64884.1 - 0.13 12.3 4.8 0.11 12.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) Glyco_hydro_63 PF03200.16 EMR64885.1 - 1.4e-09 37.3 9.0 3.6e-07 29.3 0.2 4.6 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain Aldo_ket_red PF00248.21 EMR64886.1 - 2.4e-69 233.8 0.0 2.8e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2514 PF10721.9 EMR64886.1 - 0.48 10.4 2.9 0.91 9.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) FMN_red PF03358.15 EMR64887.1 - 2.9e-14 53.1 0.0 5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMR64887.1 - 3.3e-06 27.0 0.0 5.5e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Corona_3 PF04694.12 EMR64887.1 - 0.09 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Coronavirus ORF3 protein Auto_anti-p27 PF06677.12 EMR64887.1 - 0.13 12.4 2.4 0.24 11.6 2.4 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_S27e PF01667.17 EMR64887.1 - 0.14 11.9 0.3 0.28 10.9 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 Thioredoxin_2 PF13098.6 EMR64887.1 - 0.15 12.6 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain adh_short_C2 PF13561.6 EMR64888.1 - 3e-50 171.0 0.0 3.7e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR64888.1 - 6.6e-43 146.5 0.0 8.2e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR64888.1 - 4.5e-08 33.2 0.0 7.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DNA_pol3_beta_3 PF02768.15 EMR64888.1 - 0.081 12.8 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Chorion_1 PF01723.16 EMR64888.1 - 0.22 11.5 2.0 0.22 11.5 0.8 1.6 2 0 0 2 2 2 0 Chorion protein DUF1921 PF09081.10 EMR64888.1 - 0.48 10.7 2.1 1 9.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) SNF2_N PF00176.23 EMR64889.1 - 3.1e-09 36.0 0.0 7.2e-06 25.0 0.0 2.7 3 0 0 3 3 3 2 SNF2 family N-terminal domain ResIII PF04851.15 EMR64889.1 - 1.5e-06 28.3 2.0 0.002 18.1 2.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMR64889.1 - 6.4e-05 23.3 0.0 0.00019 21.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMR64889.1 - 9e-05 22.3 0.0 0.0095 15.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase FAD_binding_3 PF01494.19 EMR64890.1 - 3.2e-26 92.4 0.0 4.6e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR64890.1 - 3.6e-10 40.0 3.3 7.9e-06 25.7 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR64890.1 - 4.2e-08 32.8 1.9 0.0018 17.6 0.6 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR64890.1 - 3.3e-06 27.6 0.3 0.0062 17.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR64890.1 - 1e-05 24.5 2.3 0.0012 17.6 1.2 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMR64890.1 - 3.1e-05 23.2 2.8 3.1e-05 23.2 2.8 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EMR64890.1 - 0.00015 21.3 2.5 0.00034 20.1 2.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMR64890.1 - 0.00041 19.6 0.2 0.0035 16.5 0.6 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EMR64890.1 - 0.00051 20.2 0.9 0.0013 18.9 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EMR64890.1 - 0.0015 17.6 0.0 0.0077 15.3 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.17 EMR64890.1 - 0.016 14.5 0.4 0.025 13.8 0.4 1.2 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 EMR64890.1 - 0.027 13.8 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EMR64890.1 - 0.052 12.8 0.2 0.97 8.6 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR64890.1 - 0.084 11.9 1.6 0.76 8.8 1.6 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EMR64890.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EMR64890.1 - 0.13 11.1 0.9 0.22 10.4 0.4 1.5 1 1 1 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.16 EMR64891.1 - 6.6e-17 61.5 12.5 8.1e-17 61.2 12.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FA_desaturase PF00487.24 EMR64891.1 - 9.7 5.9 9.1 6.9 6.4 0.1 2.9 2 1 1 3 3 3 0 Fatty acid desaturase zf_C2H2_ZHX PF18387.1 EMR64892.1 - 0.00014 21.4 2.7 0.0003 20.4 2.7 1.5 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain OrsD PF12013.8 EMR64892.1 - 0.016 15.6 0.1 0.033 14.6 0.1 1.5 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D adh_short_C2 PF13561.6 EMR64893.1 - 6.2e-46 156.9 0.0 7.7e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR64893.1 - 2e-42 144.9 0.0 2.5e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR64893.1 - 0.0086 16.0 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.15 EMR64893.1 - 0.01 15.7 0.7 0.079 12.8 0.7 2.0 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ETF PF01012.21 EMR64893.1 - 0.03 14.2 4.3 0.047 13.6 1.9 2.0 2 0 0 2 2 2 0 Electron transfer flavoprotein domain THF_DHG_CYH_C PF02882.19 EMR64893.1 - 0.056 12.8 0.2 1.6 8.0 0.0 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LytR_C PF13399.6 EMR64893.1 - 0.075 14.0 0.2 0.87 10.6 0.6 2.2 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Bromodomain PF00439.25 EMR64894.1 - 2.9e-26 91.3 1.0 6e-26 90.3 1.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EMR64894.1 - 6.4e-08 32.8 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR64894.1 - 7.2e-07 29.2 0.2 1.7e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR64894.1 - 0.0003 21.2 0.3 0.00062 20.1 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_hydro_43 PF04616.14 EMR64895.1 - 3e-23 82.5 0.0 3.5e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Rad1 PF02144.16 EMR64897.1 - 1.7e-45 155.3 0.0 2.1e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 GFA PF04828.14 EMR64898.1 - 6.4e-17 61.7 7.4 1.1e-09 38.5 0.2 3.4 2 1 1 3 3 3 3 Glutathione-dependent formaldehyde-activating enzyme SF1-HH PF16275.5 EMR64899.1 - 2.8e-11 43.7 0.0 5.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EMR64899.1 - 0.05 13.4 0.7 0.45 10.4 0.7 2.3 1 1 0 1 1 1 0 KH domain Endotoxin_C2 PF18449.1 EMR64899.1 - 0.32 11.3 1.9 0.37 11.1 0.2 1.9 2 0 0 2 2 2 0 Delta endotoxin F-box-like PF12937.7 EMR64900.1 - 8.1e-05 22.4 1.3 0.0018 18.1 1.3 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EMR64900.1 - 0.015 15.1 0.1 6.9 6.7 0.1 2.4 2 0 0 2 2 2 0 F-box domain FAA_hydrolase PF01557.18 EMR64901.1 - 2.5e-55 187.5 0.0 3.6e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EMR64901.1 - 8.6e-32 109.5 0.0 2.3e-31 108.1 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal PBP1_TM PF14812.6 EMR64902.1 - 0.016 15.5 9.5 0.023 15.0 9.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0492 PF15744.5 EMR64902.1 - 0.1 11.8 2.3 0.12 11.5 2.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 NTP_transferase PF00483.23 EMR64903.1 - 7.8e-29 101.0 0.0 1.1e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EMR64903.1 - 1.5e-09 37.2 4.3 2.2e-06 27.2 0.0 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EMR64903.1 - 4.3e-06 27.2 0.0 6.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EMR64903.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Peptidase_M54 PF07998.11 EMR64905.1 - 6.5e-08 32.8 0.2 1.6e-07 31.5 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M54 Glyco_hydro_43 PF04616.14 EMR64906.1 - 5.2e-33 114.6 1.6 1.3e-31 110.0 1.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Aldedh PF00171.22 EMR64907.1 - 1.3e-74 251.4 2.9 5.5e-40 137.2 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family HHH_5 PF14520.6 EMR64907.1 - 0.069 13.8 0.1 0.36 11.5 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain CALCOCO1 PF07888.11 EMR64909.1 - 0.0011 17.9 21.7 0.0016 17.4 21.7 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.9 EMR64909.1 - 0.0051 16.0 13.1 0.0051 16.0 13.1 2.1 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 FPP PF05911.11 EMR64909.1 - 0.013 13.7 20.1 0.019 13.2 20.1 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil MAD PF05557.13 EMR64909.1 - 0.033 12.6 26.0 0.2 10.0 4.7 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein SOGA PF11365.8 EMR64909.1 - 0.048 14.8 3.0 0.048 14.8 3.0 3.5 2 1 2 4 4 4 0 Protein SOGA Spc7 PF08317.11 EMR64909.1 - 0.056 12.3 24.1 0.01 14.7 19.8 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Trns_repr_metal PF02583.17 EMR64909.1 - 0.074 13.4 2.2 1.9 8.9 1.6 3.0 1 1 1 2 2 2 0 Metal-sensitive transcriptional repressor FAM76 PF16046.5 EMR64909.1 - 1.1 8.6 13.7 1.8 7.8 13.7 1.3 1 0 0 1 1 1 0 FAM76 protein USP8_interact PF08941.10 EMR64909.1 - 3.5 7.4 9.4 0.34 10.7 2.1 2.8 1 1 3 4 4 4 0 USP8 interacting DUF1664 PF07889.12 EMR64909.1 - 4.6 7.3 14.6 13 5.8 2.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 EMR64909.1 - 6.4 7.5 27.4 0.28 11.8 13.8 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BST2 PF16716.5 EMR64909.1 - 6.6 7.4 25.6 0.56 10.8 6.9 3.6 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF4446 PF14584.6 EMR64909.1 - 6.8 6.7 12.9 0.78 9.7 3.2 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF4446) GrpE PF01025.19 EMR64909.1 - 7.4 6.2 18.0 0.33 10.6 10.7 2.2 1 1 1 2 2 2 0 GrpE Tup_N PF08581.10 EMR64909.1 - 9.9 6.5 15.2 3.3 8.1 3.9 3.7 2 1 2 4 4 4 0 Tup N-terminal NAD_binding_10 PF13460.6 EMR64910.1 - 7.9e-08 32.4 0.1 1.6e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR64910.1 - 6.1e-06 25.9 0.0 0.091 12.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMR64910.1 - 6.9e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EMR64910.1 - 0.00025 20.3 0.1 0.0014 17.9 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 EMR64910.1 - 0.0012 19.3 0.0 0.0029 18.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EMR64910.1 - 0.026 15.2 0.0 0.051 14.3 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.19 EMR64910.1 - 0.16 11.0 0.0 2.4 7.1 0.0 2.5 2 1 1 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1996 PF09362.10 EMR64911.1 - 5.3e-82 275.3 0.9 6.6e-82 275.0 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fungal_trans PF04082.18 EMR64914.1 - 5.7e-09 35.4 0.7 1.4e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain T6SS-SciN PF12790.7 EMR64914.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 TetR_N PF00440.23 EMR64914.1 - 0.76 9.6 2.5 0.56 10.0 0.2 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family DHDPS PF00701.22 EMR64915.1 - 9e-66 221.5 0.0 1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Proteasome PF00227.26 EMR64916.1 - 2.6e-60 203.2 0.1 3.2e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMR64916.1 - 2.7e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EMR64916.1 - 0.013 15.6 0.3 0.04 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EMR64916.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit TFIIS_M PF07500.14 EMR64917.1 - 1.7e-16 60.7 3.1 3.7e-16 59.6 3.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EMR64917.1 - 7.6e-15 55.1 0.0 1.5e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 EMR64917.1 - 2.3e-09 37.0 7.3 4.2e-09 36.2 7.3 1.4 1 0 0 1 1 1 1 PHD-finger DUF4050 PF13259.6 EMR64917.1 - 0.0014 19.0 5.9 0.0014 19.0 5.9 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) PHD_2 PF13831.6 EMR64917.1 - 0.16 11.6 2.6 0.29 10.7 2.6 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 EMR64917.1 - 0.31 11.0 2.9 0.81 9.7 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 BUD22 PF09073.10 EMR64918.1 - 0.0013 18.1 1.6 0.0017 17.8 1.6 1.2 1 0 0 1 1 1 1 BUD22 EphA2_TM PF14575.6 EMR64918.1 - 0.028 15.3 0.0 0.064 14.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 EMR64918.1 - 0.032 14.0 0.1 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CDC45 PF02724.14 EMR64918.1 - 0.086 11.1 2.1 0.1 10.9 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 EMR64918.1 - 0.17 11.5 15.2 0.28 10.9 15.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SKG6 PF08693.10 EMR64918.1 - 0.29 10.6 4.3 0.57 9.6 4.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain eIF-3c_N PF05470.12 EMR64918.1 - 0.36 9.1 1.1 0.41 8.9 1.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Adeno_terminal PF02459.15 EMR64918.1 - 0.5 8.7 2.2 1 7.7 2.2 1.5 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF4690 PF15756.5 EMR64918.1 - 2.1 9.0 8.7 5.5 7.7 5.6 3.0 2 1 0 2 2 2 0 Small Novel Rich in Cartilage Na_trans_assoc PF06512.13 EMR64918.1 - 2.9 8.1 7.4 4.6 7.5 7.4 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 EMR64918.1 - 3.9 5.6 11.4 5.7 5.0 11.4 1.2 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 EMR64918.1 - 7.1 6.9 18.0 7.9 6.8 16.2 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DGF-1_C PF11040.8 EMR64919.1 - 0.036 14.1 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus p450 PF00067.22 EMR64920.1 - 1.8e-73 247.9 0.0 2.3e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Formyl_trans_N PF00551.19 EMR64921.1 - 4.1e-38 130.9 0.2 5.2e-38 130.6 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EMR64921.1 - 4e-11 42.5 0.0 2.2e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 EMR64921.1 - 0.00044 20.2 0.0 0.0021 18.0 0.0 2.1 3 0 0 3 3 3 1 ACT domain ACT_4 PF13291.6 EMR64921.1 - 0.15 12.6 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 ACT domain RWD PF05773.22 EMR64923.1 - 3.4e-25 88.6 0.7 4.8e-25 88.1 0.7 1.2 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EMR64923.1 - 0.0001 22.7 2.2 0.00023 21.6 2.2 1.6 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF2852 PF11014.8 EMR64923.1 - 0.15 12.3 1.5 0.21 11.8 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) CPL PF08144.11 EMR64925.1 - 9.1e-31 107.1 0.7 1.4e-28 100.0 0.0 4.0 4 2 0 4 4 4 1 CPL (NUC119) domain SBP_bac_6 PF13343.6 EMR64925.1 - 0.0066 15.9 0.1 0.014 14.8 0.1 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein LAP1C PF05609.12 EMR64925.1 - 0.2 10.7 14.7 0.011 14.8 5.6 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) SWIB PF02201.18 EMR64925.1 - 0.34 10.8 2.8 2.8 7.9 0.1 3.3 3 0 0 3 3 3 0 SWIB/MDM2 domain Rhomboid PF01694.22 EMR64926.1 - 4.6e-20 72.2 14.4 8.3e-20 71.3 14.4 1.4 1 0 0 1 1 1 1 Rhomboid family DUF2157 PF09925.9 EMR64926.1 - 1.3 8.8 9.1 2.4 8.0 0.4 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) TPR_12 PF13424.6 EMR64927.1 - 2.8e-10 40.3 16.6 3.7e-05 23.9 11.0 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMR64927.1 - 7.1e-10 38.3 1.0 4.7e-05 23.3 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR64927.1 - 3.4e-09 36.1 19.8 1e-05 25.3 0.8 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMR64927.1 - 3.9e-09 36.6 26.4 0.033 15.0 1.5 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMR64927.1 - 6.2e-07 29.0 10.0 0.00013 21.7 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMR64927.1 - 1.1e-05 26.0 41.2 0.00062 20.4 18.3 5.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMR64927.1 - 6.2e-05 23.4 33.8 0.012 16.0 1.6 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMR64927.1 - 0.00025 20.7 0.3 0.00025 20.7 0.3 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMR64927.1 - 0.0027 18.2 10.9 8.2 7.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMR64927.1 - 0.015 15.7 1.5 43 4.8 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMR64927.1 - 0.022 14.4 0.1 0.087 12.5 0.1 2.1 1 0 0 1 1 1 0 TPR repeat TPR_10 PF13374.6 EMR64927.1 - 0.023 14.5 1.2 0.023 14.5 1.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR64927.1 - 0.073 13.7 0.6 0.073 13.7 0.6 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Asp PF00026.23 EMR64928.1 - 5.9e-68 229.6 5.1 7.6e-68 229.2 5.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EMR64928.1 - 1.7e-06 28.6 1.4 0.036 14.7 0.3 3.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.6 EMR64928.1 - 2e-05 24.9 15.3 9.7e-05 22.7 6.1 4.2 3 2 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EMR64928.1 - 0.00033 20.5 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Lipocalin_4 PF13648.6 EMR64928.1 - 2.8 9.0 9.5 0.45 11.5 0.5 2.9 3 1 0 3 3 3 0 Lipocalin-like domain ATP-synt_C PF00137.21 EMR64929.1 - 1.5e-09 38.1 27.0 3.9e-06 27.1 10.0 2.2 2 0 0 2 2 2 2 ATP synthase subunit C MFS_1 PF07690.16 EMR64930.1 - 1.6e-17 63.5 31.3 3e-17 62.6 31.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR64930.1 - 1.7e-15 56.5 10.0 2.3e-15 56.1 10.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMR64930.1 - 0.00012 21.1 12.7 0.00012 21.1 12.7 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Head-tail_con PF12236.8 EMR64930.1 - 0.11 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Acyl_transf_3 PF01757.22 EMR64931.1 - 6.3e-26 91.2 12.1 2.5e-19 69.5 6.4 2.3 2 0 0 2 2 2 2 Acyltransferase family SUIM_assoc PF16619.5 EMR64931.1 - 3.3 7.9 14.6 3.7 7.7 6.2 2.6 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3446 PF11928.8 EMR64931.1 - 7.1 7.0 17.4 0.89 9.9 11.3 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Lactamase_B_2 PF12706.7 EMR64933.1 - 9.7e-16 57.9 0.1 1.7e-15 57.1 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMR64933.1 - 3.4e-11 43.3 0.0 4.9e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain E1-E2_ATPase PF00122.20 EMR64934.1 - 3.4e-40 137.5 5.2 2.3e-31 108.7 0.0 2.8 1 1 1 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMR64934.1 - 3.4e-26 92.1 2.5 3.4e-26 92.1 2.5 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMR64934.1 - 1.7e-18 67.7 1.2 1.5e-14 54.8 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMR64934.1 - 5e-14 52.2 0.0 1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMR64934.1 - 9.9e-06 25.5 1.8 0.00013 21.8 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EMR64934.1 - 0.034 14.0 0.6 0.034 14.0 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) Peptidase_S8 PF00082.22 EMR64935.1 - 1.4e-33 116.4 13.5 3.2e-33 115.3 13.5 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR64935.1 - 4.1e-11 43.4 1.2 8.5e-11 42.4 1.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Amidohydro_3 PF07969.11 EMR64936.1 - 1.7e-71 242.2 4.4 2e-71 241.9 4.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EMR64936.1 - 2e-11 43.8 0.0 3.4e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Sugar_tr PF00083.24 EMR64937.1 - 1.5e-80 271.3 34.9 1.4e-66 225.3 26.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR64937.1 - 2e-25 89.5 25.7 1.2e-24 86.9 21.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR64937.1 - 0.00014 20.4 3.5 0.0003 19.3 3.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SDA1 PF05285.12 EMR64938.1 - 0.27 10.6 15.4 0.38 10.1 15.4 1.1 1 0 0 1 1 1 0 SDA1 CKAP2_C PF15297.6 EMR64938.1 - 0.81 8.7 7.0 1.3 8.0 6.3 1.6 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Cu-oxidase_2 PF07731.14 EMR64939.1 - 5.7e-44 149.2 5.9 7.4e-39 132.6 0.8 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMR64939.1 - 2e-41 140.7 2.6 1.1e-40 138.4 1.3 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EMR64939.1 - 2e-33 115.8 0.1 2.5e-32 112.2 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Zn_clus PF00172.18 EMR64940.1 - 0.00025 21.1 11.8 0.00045 20.3 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5098 PF17023.5 EMR64940.1 - 0.019 13.9 0.4 0.027 13.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) Mtc PF03820.17 EMR64941.1 - 3.9e-118 394.0 0.0 4.4e-118 393.9 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF4131 PF13567.6 EMR64942.1 - 3.2 7.4 6.8 3.5 7.3 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 EMR64943.1 - 2.8e-30 105.6 0.0 4.7e-24 85.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR64943.1 - 2.4e-13 50.0 0.0 3.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1357 PF07094.11 EMR64943.1 - 0.0055 16.8 1.8 0.062 13.4 0.2 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF1357) Kinase-like PF14531.6 EMR64943.1 - 0.013 14.8 0.2 2.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 EMR64943.1 - 0.072 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EMR64943.1 - 0.11 12.1 0.1 0.47 10.0 0.0 2.1 2 1 0 2 2 2 0 RIO1 family Exo_endo_phos PF03372.23 EMR64945.1 - 1.2e-12 47.9 0.7 1.8e-12 47.3 0.7 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family He_PIG PF05345.12 EMR64945.1 - 0.015 15.4 6.0 0.061 13.5 6.0 2.1 1 0 0 1 1 1 0 Putative Ig domain Exo_endo_phos_2 PF14529.6 EMR64945.1 - 0.038 13.8 0.0 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase fn3_3 PF14686.6 EMR64945.1 - 0.19 11.6 2.7 4.6 7.1 0.1 3.3 3 1 1 4 4 4 0 Polysaccharide lyase family 4, domain II Aldo_ket_red PF00248.21 EMR64946.1 - 5.4e-74 249.0 0.0 6.3e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fe-ADH PF00465.19 EMR64947.1 - 6e-52 176.7 1.2 4.7e-35 121.1 0.2 2.0 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMR64947.1 - 2.5e-09 37.2 0.0 3.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PhageMin_Tail PF10145.9 EMR64947.1 - 0.097 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Phage-related minor tail protein Glyco_hydro_125 PF06824.11 EMR64948.1 - 1.4e-161 538.0 0.0 1.6e-161 537.9 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) RNase_H PF00075.24 EMR64949.1 - 0.00064 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 RNase H DUF3292 PF11696.8 EMR64949.1 - 0.017 13.5 1.6 0.025 13.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) OGFr_III PF04680.13 EMR64949.1 - 0.08 13.6 4.8 0.17 12.5 4.8 1.6 1 0 0 1 1 1 0 Opioid growth factor receptor repeat Pilosulin PF17499.2 EMR64949.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Ant venom peptides DUF3510 PF12022.8 EMR64949.1 - 2.6 8.4 5.7 4.2 7.8 2.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) LigB PF02900.18 EMR64950.1 - 3.3e-34 118.2 0.0 4.1e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.16 EMR64951.1 - 7.8e-26 90.8 18.7 7.8e-26 90.8 18.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR64951.1 - 5e-07 28.5 6.3 7.8e-07 27.9 6.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HgmA PF04209.13 EMR64953.1 - 1.6e-144 481.8 0.9 2.4e-118 395.5 0.0 2.0 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase Fungal_trans_2 PF11951.8 EMR64954.1 - 1e-47 162.8 0.2 1.6e-47 162.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2434 PF10361.9 EMR64955.1 - 1.7e-122 408.1 6.9 2e-122 407.8 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) MFS_1 PF07690.16 EMR64955.1 - 2 7.3 13.9 0.71 8.7 6.5 2.2 1 1 1 2 2 2 0 Major Facilitator Superfamily COesterase PF00135.28 EMR64957.1 - 9.9e-22 77.5 0.0 2.3e-15 56.5 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family adh_short_C2 PF13561.6 EMR64958.1 - 3.9e-07 29.9 0.1 5.1e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR64958.1 - 6.6e-07 29.0 0.0 9.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EMR64958.1 - 0.0004 19.9 0.0 0.0015 18.0 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMR64958.1 - 0.00046 19.4 0.1 0.00059 19.0 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAM-associated PF14303.6 EMR64959.1 - 0.077 13.7 6.1 0.075 13.8 6.1 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF883 PF05957.13 EMR64959.1 - 0.12 13.0 6.7 0.15 12.7 6.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Fmp27_WPPW PF10359.9 EMR64959.1 - 0.2 10.5 5.4 0.2 10.5 5.4 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Macoilin PF09726.9 EMR64959.1 - 0.28 9.7 5.7 0.27 9.8 5.7 1.0 1 0 0 1 1 1 0 Macoilin family DUF4337 PF14235.6 EMR64959.1 - 0.32 11.1 7.2 0.34 11.0 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Phage_Mu_Gam PF07352.12 EMR64959.1 - 0.34 10.8 8.5 0.47 10.4 8.5 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF2229 PF09989.9 EMR64959.1 - 1.5 8.4 3.5 1.6 8.3 3.5 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF4407 PF14362.6 EMR64959.1 - 1.7 7.9 10.2 2.1 7.6 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EMR64959.1 - 3.2 7.6 10.6 0.56 10.0 5.1 2.0 1 1 1 2 2 2 0 Septum formation initiator NmrA PF05368.13 EMR64960.1 - 7.4e-64 215.5 0.3 1.1e-63 215.0 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family Aldedh PF00171.22 EMR64960.1 - 1.3e-52 178.9 0.0 8.6e-37 126.7 0.0 2.4 1 1 1 2 2 2 2 Aldehyde dehydrogenase family NAD_binding_10 PF13460.6 EMR64960.1 - 1.8e-15 57.3 0.5 7.9e-15 55.2 0.1 2.2 2 1 0 2 2 2 1 NAD(P)H-binding Amidase PF01425.21 EMR64960.1 - 0.014 14.3 0.2 0.025 13.5 0.2 1.3 1 0 0 1 1 1 0 Amidase adh_short_C2 PF13561.6 EMR64960.1 - 0.05 13.2 0.6 0.11 12.0 0.6 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Aminotran_3 PF00202.21 EMR64961.1 - 7.1e-94 314.7 0.0 1.1e-93 314.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMR64961.1 - 4.2e-05 22.9 0.0 0.00025 20.4 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Aa_trans PF01490.18 EMR64962.1 - 4.2e-60 203.6 38.3 4.8e-60 203.4 38.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0242 PF06785.11 EMR64962.1 - 1.9 8.6 6.2 2.2 8.3 1.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus 2OG-FeII_Oxy PF03171.20 EMR64963.1 - 9e-14 51.8 0.0 1.6e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMR64963.1 - 8e-11 42.7 0.0 1.8e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal NAP PF00956.18 EMR64964.1 - 1e-18 67.5 0.6 1.4e-18 67.1 0.6 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) EF-hand_1 PF00036.32 EMR64965.1 - 5.7e-21 72.4 1.7 4.3e-09 35.3 0.4 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EMR64965.1 - 9e-21 74.1 0.0 3.1e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EMR64965.1 - 6.5e-18 64.3 2.1 1.9e-11 43.6 0.3 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EMR64965.1 - 2.8e-15 54.9 0.2 6e-05 22.7 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 EMR64965.1 - 1.8e-09 37.7 0.0 7.3e-07 29.4 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EMR64965.1 - 1.2e-08 34.1 8.6 9e-05 21.8 0.4 3.2 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 EMR64965.1 - 3.2e-05 23.8 0.1 0.00038 20.4 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 EMR64965.1 - 0.00036 20.5 0.0 0.053 13.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 EMR64965.1 - 0.0015 19.4 0.0 0.05 14.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain DUF3349 PF11829.8 EMR64965.1 - 0.0024 18.6 0.0 0.094 13.5 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3349) Adenine_glyco PF03352.13 EMR64965.1 - 0.018 14.8 0.0 0.57 9.9 0.0 2.0 1 1 0 2 2 2 0 Methyladenine glycosylase SPARC_Ca_bdg PF10591.9 EMR64965.1 - 0.021 15.1 0.1 0.43 10.9 0.0 2.4 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DnaB_2 PF07261.11 EMR64965.1 - 0.03 14.1 0.1 0.72 9.6 0.0 2.7 3 0 0 3 3 3 0 Replication initiation and membrane attachment Tricorn_C1 PF14684.6 EMR64965.1 - 0.13 12.3 0.0 0.7 10.0 0.0 2.2 2 1 0 2 2 2 0 Tricorn protease C1 domain EF-hand_14 PF17959.1 EMR64965.1 - 0.15 12.5 0.0 7.6 7.0 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain Amidohydro_1 PF01979.20 EMR64967.1 - 1.8e-29 103.2 0.1 7e-29 101.2 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR64967.1 - 5e-12 46.0 4.0 1.2e-07 31.7 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family Rep_fac-A_C PF08646.10 EMR64968.1 - 1.5e-58 196.7 4.3 2.8e-56 189.3 0.8 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EMR64968.1 - 1.4e-38 130.7 0.3 1.9e-37 127.1 0.2 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EMR64968.1 - 6.6e-19 67.8 0.0 1.4e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EMR64968.1 - 1.1e-16 60.6 1.3 9.6e-11 41.5 0.0 5.0 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EMR64968.1 - 1.5e-05 24.9 0.1 0.079 12.7 0.0 2.6 2 0 0 2 2 2 2 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 EMR64968.1 - 0.0022 18.3 0.2 0.0048 17.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF223 tRNA_anti_2 PF13742.6 EMR64968.1 - 0.0043 17.2 1.5 1.8 8.8 0.0 3.8 5 0 0 5 5 5 1 OB-fold nucleic acid binding domain zf-like PF04071.12 EMR64968.1 - 0.038 13.9 0.3 0.089 12.7 0.3 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain POT1 PF02765.17 EMR64968.1 - 0.1 12.4 0.3 1.2 8.9 0.0 2.8 4 0 0 4 4 4 0 Telomeric single stranded DNA binding POT1/CDC13 DUF4539 PF15072.6 EMR64968.1 - 0.11 12.5 0.0 2.7 8.1 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4539) MFS_1 PF07690.16 EMR64969.1 - 2.9e-14 52.8 45.7 2.9e-14 52.8 45.7 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR64969.1 - 8e-06 25.6 6.7 8e-06 25.6 6.7 3.0 3 2 0 3 3 3 1 Ion channel regulatory protein UNC-93 ACAS_N PF16177.5 EMR64970.1 - 2.7e-19 68.8 2.6 4.1e-11 42.6 0.2 2.2 2 0 0 2 2 2 2 Acetyl-coenzyme A synthetase N-terminus AMP-binding PF00501.28 EMR64970.1 - 0.014 14.1 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme SR-25 PF10500.9 EMR64970.1 - 0.11 12.1 14.0 0.13 11.9 14.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EMR64970.1 - 0.37 8.8 15.4 0.43 8.6 15.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 EMR64970.1 - 0.47 8.9 2.8 0.51 8.8 2.8 1.0 1 0 0 1 1 1 0 Macoilin family SUZ PF12752.7 EMR64970.1 - 4.8 8.0 6.6 9.8 7.0 6.6 1.6 1 0 0 1 1 1 0 SUZ domain ADH_zinc_N PF00107.26 EMR64971.1 - 1.1e-22 80.4 0.1 2e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR64971.1 - 1.6e-18 68.1 0.0 2.8e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR64971.1 - 5.6e-08 32.6 0.0 2.8e-07 30.4 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Bac_rhodopsin PF01036.18 EMR64972.1 - 4.8e-48 163.7 19.1 6.6e-48 163.2 19.1 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Phage_holin_3_6 PF07332.11 EMR64972.1 - 1.1 9.4 8.8 0.27 11.3 0.4 2.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III CcmD PF04995.14 EMR64973.1 - 0.073 13.2 0.7 0.16 12.1 0.7 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) 2Fe-2S_thioredx PF01257.19 EMR64974.1 - 2.5e-60 202.5 0.1 3.2e-60 202.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Kelch_3 PF13415.6 EMR64975.1 - 1.3e-25 89.1 10.9 7e-07 29.4 0.1 8.3 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EMR64975.1 - 3.5e-22 78.1 12.8 6.3e-08 32.5 0.0 6.8 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EMR64975.1 - 2.8e-20 71.8 0.1 6.2e-05 22.9 0.0 6.6 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 EMR64975.1 - 1.6e-18 66.2 2.7 0.00026 21.2 0.1 5.7 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EMR64975.1 - 1.8e-17 62.7 3.5 1.4e-05 24.6 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EMR64975.1 - 2.2e-13 49.6 1.3 0.00023 21.0 0.0 5.4 5 0 0 5 5 5 3 Kelch motif dCMP_cyt_deam_1 PF00383.23 EMR64976.1 - 5.5e-07 29.4 0.0 0.00013 21.8 0.0 2.9 3 0 0 3 3 3 2 Cytidine and deoxycytidylate deaminase zinc-binding region Phostensin_N PF13916.6 EMR64976.1 - 1.8 9.0 5.2 0.54 10.6 1.8 1.9 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF4834 PF16118.5 EMR64976.1 - 4.7 8.2 9.1 0.2 12.6 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DLH PF01738.18 EMR64978.1 - 3.3e-23 82.4 0.0 2.3e-21 76.4 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EMR64978.1 - 0.0026 17.5 0.0 0.2 11.3 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EMR64978.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AhpC-TSA PF00578.21 EMR64979.1 - 1.2e-25 89.8 0.0 1.9e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMR64979.1 - 2.1e-16 59.9 0.0 3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EMR64979.1 - 0.0016 18.5 0.0 0.007 16.5 0.0 1.9 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme CBS PF00571.28 EMR64979.1 - 0.18 12.3 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 CBS domain PCI PF01399.27 EMR64980.1 - 0.045 14.3 0.0 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 PCI domain ACTH_assoc PF16102.5 EMR64980.1 - 0.094 13.5 1.0 0.36 11.7 1.0 2.0 1 0 0 1 1 1 0 ACTH-associated domain K_channel_TID PF07941.11 EMR64980.1 - 0.19 12.2 1.9 0.43 11.1 1.9 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SesA PF17107.5 EMR64980.1 - 0.44 10.8 2.5 11 6.3 0.4 2.3 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases p450 PF00067.22 EMR64981.1 - 7.6e-48 163.4 0.0 6e-30 104.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF3573 PF12097.8 EMR64983.1 - 0.1 11.4 0.5 0.14 11.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Methyltransf_11 PF08241.12 EMR64984.1 - 0.012 16.3 0.0 0.066 13.9 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 EMR64984.1 - 0.023 15.4 0.0 0.046 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EMR64984.1 - 0.05 14.3 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMR64984.1 - 0.069 13.0 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cu-oxidase_3 PF07732.15 EMR64985.1 - 3.5e-40 136.7 5.7 1.8e-37 128.0 1.5 3.7 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMR64985.1 - 1.2e-39 135.1 6.0 1.8e-39 134.6 0.1 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EMR64985.1 - 2.1e-36 125.4 1.2 9.9e-35 120.0 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase FTR1 PF03239.14 EMR64986.1 - 1.1e-82 277.7 8.8 1.3e-82 277.4 8.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF2615 PF11027.8 EMR64986.1 - 0.095 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Phage_holin_3_6 PF07332.11 EMR64986.1 - 4.9 7.2 17.0 0.17 12.0 3.7 3.3 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Myb_DNA-bind_4 PF13837.6 EMR64988.1 - 7.8e-05 23.0 0.1 0.00036 20.8 0.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pex19 PF04614.12 EMR64988.1 - 0.014 15.2 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Pex19 protein family DUF5525 PF17663.1 EMR64988.1 - 0.089 10.9 7.0 0.1 10.6 7.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) VPS11_C PF12451.8 EMR64988.1 - 0.13 12.5 0.7 0.21 11.8 0.7 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal Retrotran_gag_2 PF14223.6 EMR64988.1 - 0.17 11.6 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NPDC1 PF06809.11 EMR64989.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Sacchrp_dh_C PF16653.5 EMR64991.1 - 2.9e-94 316.1 0.0 5.5e-94 315.2 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EMR64991.1 - 1.2e-24 87.0 0.3 1.8e-24 86.4 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMR64991.1 - 2e-05 24.7 0.2 4.6e-05 23.5 0.2 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EMR64991.1 - 0.0016 18.4 0.4 0.0038 17.2 0.2 1.9 2 1 0 2 2 2 1 NAD(P)H-binding IlvN PF07991.12 EMR64991.1 - 0.015 14.9 0.2 0.051 13.1 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 EMR64991.1 - 0.087 13.7 0.1 0.17 12.7 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Mcp5_PH PF12814.7 EMR64992.1 - 7.8e-48 161.6 0.7 2e-47 160.3 0.0 2.1 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology ERM PF00769.19 EMR64992.1 - 0.0069 16.2 13.1 0.0069 16.2 13.1 2.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Fez1 PF06818.15 EMR64992.1 - 0.018 15.5 17.7 0.038 14.5 17.7 1.5 1 0 0 1 1 1 0 Fez1 PH_12 PF16457.5 EMR64992.1 - 0.057 13.9 0.1 0.29 11.7 0.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain TPR_MLP1_2 PF07926.12 EMR64992.1 - 0.099 12.7 24.8 0.24 11.5 20.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EMR64992.1 - 1.4 8.2 11.3 2.7 7.3 11.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EMR64992.1 - 1.4 9.0 12.4 2.4 8.2 12.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EMR64992.1 - 2.1 7.9 8.8 3.7 7.0 8.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EMR64992.1 - 3.2 6.6 16.0 5 5.9 16.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PALP PF00291.25 EMR64993.1 - 1.9e-07 30.8 0.0 2.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UQ_con PF00179.26 EMR64994.1 - 3e-37 127.4 0.0 3.9e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMR64994.1 - 0.025 14.3 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EMR64994.1 - 0.054 13.8 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EMR64994.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Hydrolase PF00702.26 EMR64995.1 - 1.4e-09 38.6 0.0 2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR64995.1 - 3.3e-08 33.8 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR64995.1 - 1.1e-06 28.5 0.0 2.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like IlvC PF01450.19 EMR64996.1 - 1.7e-42 145.1 0.0 2.7e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 EMR64996.1 - 1.7e-21 76.5 0.0 3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NmrA PF05368.13 EMR64997.1 - 2.3e-64 217.1 0.0 2.8e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR64997.1 - 1.2e-16 61.2 0.0 1.6e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EMR64997.1 - 9.7e-06 24.8 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EMR64997.1 - 0.0049 17.1 0.1 0.0076 16.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 EMR64997.1 - 0.015 14.9 0.3 0.024 14.2 0.3 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ELFV_dehydrog_N PF02812.18 EMR64997.1 - 0.026 14.4 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain GMC_oxred_C PF05199.13 EMR64998.1 - 7.5e-25 88.1 0.0 7.9e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase p450 PF00067.22 EMR64999.1 - 4.5e-18 65.3 0.0 6.4e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 EMR64999.1 - 1.1e-09 38.1 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EMR64999.1 - 0.0047 16.0 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein PIG-U PF06728.13 EMR65000.1 - 1.4e-121 406.2 29.0 1.6e-121 406.0 29.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 EMR65000.1 - 4.7e-05 23.4 0.4 4.7e-05 23.4 0.4 1.8 1 1 1 2 2 2 1 Mannosyltransferase (PIG-M) Peroxin-13_N PF04088.13 EMR65001.1 - 1.6e-51 174.4 0.1 2.2e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EMR65001.1 - 6.8e-09 35.3 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMR65001.1 - 1.4e-07 31.0 0.0 2.8e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMR65001.1 - 9.4e-07 28.6 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PRIMA1 PF16101.5 EMR65001.1 - 0.37 10.8 4.5 0.86 9.7 4.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4663 PF15668.5 EMR65001.1 - 8.1 5.4 6.9 3.6 6.6 4.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4663) Pkinase_Tyr PF07714.17 EMR65004.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Neisseria_TspB PF05616.13 EMR65004.1 - 6.4 5.1 13.2 7.5 4.9 13.2 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein FAD_binding_4 PF01565.23 EMR65005.1 - 5.4e-21 74.8 1.1 1.1e-20 73.7 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR65005.1 - 2e-07 31.0 0.0 4.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.21 EMR65005.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Bax1-I PF01027.20 EMR65007.1 - 2.1e-34 119.2 10.3 3.3e-34 118.5 10.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Abhydrolase_1 PF00561.20 EMR65008.1 - 1.5e-13 51.0 0.0 9.2e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR65008.1 - 1.2e-10 42.4 0.3 1.6e-10 42.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR65008.1 - 7.3e-10 38.5 0.0 5.1e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EMR65008.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 EMR65008.1 - 0.072 13.2 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Fungal_trans PF04082.18 EMR65009.1 - 4e-09 35.9 0.5 6e-09 35.3 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 EMR65011.1 - 3.3e-78 263.6 21.2 3.8e-78 263.4 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR65011.1 - 4.8e-29 101.4 45.6 4.3e-28 98.3 26.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 EMR65011.1 - 4.2 8.0 9.8 0.45 11.1 4.2 2.3 2 1 0 2 2 2 0 Phage holin family 2 DUF2401 PF10287.9 EMR65012.1 - 7.2e-85 284.2 0.1 1.1e-84 283.7 0.1 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EMR65012.1 - 2.8e-22 78.9 0.0 5.9e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Transp_cyt_pur PF02133.15 EMR65013.1 - 2.4e-40 138.7 36.0 2.7e-38 131.9 36.0 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cyd_oper_YbgE PF09600.10 EMR65013.1 - 6.5 7.2 16.0 1.4 9.4 9.9 3.1 1 1 1 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Ank_2 PF12796.7 EMR65014.1 - 1.6e-25 89.5 4.4 2.7e-13 50.3 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR65014.1 - 4.6e-20 71.7 0.2 2e-08 34.6 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EMR65014.1 - 3.2e-17 62.1 4.6 0.00028 21.2 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat NACHT PF05729.12 EMR65014.1 - 1.1e-12 48.2 0.1 1.7e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 EMR65014.1 - 1.9e-09 36.9 2.1 0.12 13.0 0.0 5.3 6 0 0 6 6 4 3 Ankyrin repeat Ank_5 PF13857.6 EMR65014.1 - 2.3e-06 27.7 0.2 0.0043 17.3 0.1 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 EMR65014.1 - 1.5e-05 24.4 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily AAA PF00004.29 EMR65014.1 - 0.0003 21.2 0.0 0.015 15.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EMR65014.1 - 0.0004 19.7 0.0 0.00083 18.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EMR65014.1 - 0.0015 18.9 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR65014.1 - 0.0017 18.6 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMR65014.1 - 0.01 15.9 0.0 0.23 11.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMR65014.1 - 0.014 16.0 0.1 0.069 13.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMR65014.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cNMP_binding PF00027.29 EMR65015.1 - 2.6e-21 75.5 0.0 1.6e-20 73.0 0.0 2.3 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain LRR_6 PF13516.6 EMR65015.1 - 1.4e-11 43.5 1.9 0.015 15.3 0.0 6.9 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 EMR65015.1 - 2.2e-08 34.2 0.0 0.88 10.1 0.0 5.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMR65015.1 - 2.4e-05 24.3 7.5 6.9 7.6 0.0 6.2 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.6 EMR65015.1 - 0.095 12.5 0.2 13 5.7 0.0 4.0 4 2 0 4 4 4 0 Leucine rich repeat F-box PF00646.33 EMR65015.1 - 0.39 10.7 3.2 1.2 9.1 0.9 2.8 2 1 0 2 2 2 0 F-box domain RPE65 PF03055.15 EMR65016.1 - 6.2e-73 246.6 0.0 7.8e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Adenine_glyco PF03352.13 EMR65016.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyladenine glycosylase Epimerase PF01370.21 EMR65017.1 - 3.3e-09 36.6 0.1 2.1e-08 33.9 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR65017.1 - 9.2e-06 25.3 0.3 0.00012 21.6 0.2 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMR65017.1 - 4.5e-05 22.8 0.0 0.00022 20.5 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EMR65017.1 - 9.6e-05 21.5 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMR65017.1 - 0.0033 17.3 0.1 0.024 14.5 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR65017.1 - 0.024 14.2 0.2 0.25 10.9 0.2 2.2 1 1 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 EMR65017.1 - 0.056 12.6 0.4 0.51 9.4 0.1 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 EMR65018.1 - 1.5e-16 60.2 0.2 3.9e-16 58.9 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR65018.1 - 4.8e-08 33.0 9.9 9.2e-08 32.1 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 EMR65019.1 - 1.1e-08 35.2 0.3 3.9e-06 26.9 0.3 2.2 1 1 1 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 EMR65019.1 - 4.8e-05 23.0 0.5 0.019 14.6 0.4 2.2 1 1 1 2 2 2 2 NmrA-like family KR PF08659.10 EMR65019.1 - 0.00031 20.7 0.2 0.00051 20.0 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR65019.1 - 0.0018 17.8 0.1 0.0038 16.7 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EMR65019.1 - 0.07 13.7 3.4 0.29 11.7 0.2 2.5 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF3842 PF12953.7 EMR65019.1 - 0.12 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) 3Beta_HSD PF01073.19 EMR65019.1 - 0.17 10.9 0.0 0.33 9.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GMC_oxred_C PF05199.13 EMR65020.1 - 8.6e-22 78.2 0.0 1.4e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR65020.1 - 7.1e-16 58.4 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Glyco_hydro_49N PF17433.2 EMR65020.1 - 0.052 13.2 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain DUF1737 PF08410.10 EMR65020.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) HupH_C PF04809.13 EMR65020.1 - 0.11 12.2 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region TPR_2 PF07719.17 EMR65021.1 - 5.8e-12 44.8 2.7 1.3e-05 24.9 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMR65021.1 - 1.2e-07 31.3 1.7 0.048 13.5 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMR65021.1 - 6.7e-07 29.6 0.7 0.00033 21.2 0.4 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EMR65021.1 - 7.4e-05 22.8 5.2 0.024 14.8 0.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMR65021.1 - 0.00085 19.4 0.8 0.089 13.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMR65021.1 - 0.0026 18.0 6.3 0.093 13.0 6.2 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EMR65021.1 - 0.0058 16.0 1.5 0.0079 15.6 1.5 1.1 1 0 0 1 1 1 1 MalT-like TPR region Fis1_TPR_C PF14853.6 EMR65021.1 - 0.0082 16.2 0.5 0.042 13.9 0.1 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EMR65021.1 - 0.017 15.7 3.6 0.21 12.3 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.28 EMR65021.1 - 0.032 14.6 0.1 0.17 12.3 0.0 2.0 2 1 0 2 2 2 0 SET domain TPR_16 PF13432.6 EMR65021.1 - 0.081 13.6 6.7 4.2 8.1 7.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMR65021.1 - 0.12 12.3 3.6 4.1 7.4 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMR65021.1 - 0.15 12.5 4.0 0.43 11.1 3.9 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 EMR65022.1 - 7.3e-25 87.4 0.0 1.1e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR65022.1 - 2.2e-22 80.5 0.0 3.6e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR65022.1 - 7.1e-07 29.1 0.1 1.9e-06 27.7 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PMSR PF01625.21 EMR65023.1 - 1e-60 204.3 0.4 1.2e-60 204.1 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FAD_binding_3 PF01494.19 EMR65024.1 - 1.3e-17 64.1 0.5 2e-15 56.9 0.5 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR65024.1 - 0.00062 19.9 0.1 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR65024.1 - 0.032 13.5 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR65024.1 - 0.084 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.25 EMR65025.1 - 5.7e-21 74.9 0.0 1.3e-20 73.7 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65025.1 - 2.9e-12 46.6 0.0 4.3e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR65025.1 - 3.6e-05 23.7 0.0 5.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR65025.1 - 4.1e-05 23.2 0.0 5.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Csm1_B PF18211.1 EMR65025.1 - 0.035 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Csm1 subunit domain B GDP_Man_Dehyd PF16363.5 EMR65025.1 - 0.047 13.1 0.1 0.16 11.3 0.1 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EMR65025.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 EMR65025.1 - 0.087 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EMR65025.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EMR65026.1 - 3.4e-22 79.9 0.2 5.3e-22 79.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR65026.1 - 3.9e-17 62.5 0.9 6.1e-17 61.8 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR65026.1 - 7.7e-11 41.8 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EMR65026.1 - 0.12 12.7 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF2306 PF10067.9 EMR65027.1 - 9.2e-18 64.9 8.3 9.2e-18 64.9 8.3 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Hexokinase_2 PF03727.16 EMR65029.1 - 5.8e-74 248.5 0.0 7.9e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EMR65029.1 - 5e-62 209.3 0.0 6.7e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase HET PF06985.11 EMR65030.1 - 3.8e-11 43.5 0.9 3.5e-08 33.9 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.22 EMR65031.1 - 3.1e-44 151.4 0.0 1.2e-43 149.5 0.0 1.9 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EMR65031.1 - 4.3e-16 59.6 0.1 9.7e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain ADH_N PF08240.12 EMR65032.1 - 2.5e-17 62.7 0.1 2.6e-16 59.5 0.0 2.6 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR65032.1 - 2.2e-11 43.9 1.8 1.5e-10 41.2 1.8 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR65032.1 - 0.005 16.3 0.3 0.013 15.0 0.3 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus DUF1353 PF07087.11 EMR65032.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) ADH_N_assoc PF13823.6 EMR65032.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated HNH_2 PF13391.6 EMR65033.1 - 2.1e-07 31.0 0.0 5.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EMR65033.1 - 0.23 11.3 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease Beta_helix PF13229.6 EMR65034.1 - 7.1e-10 39.0 9.0 1e-08 35.2 2.8 2.4 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.6 EMR65034.1 - 0.00011 21.3 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Chondroitinase B NosD PF05048.13 EMR65034.1 - 0.0015 17.9 8.1 0.12 11.6 0.6 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EMR65034.1 - 0.038 13.3 0.1 0.038 13.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1565) Glyco_hydro_47 PF01532.20 EMR65035.1 - 5.3e-171 569.5 0.5 6.2e-171 569.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.6 EMR65035.1 - 0.097 12.3 0.6 0.5 9.9 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4038) Abhydrolase_4 PF08386.10 EMR65036.1 - 3.6e-22 78.4 0.0 7.3e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EMR65036.1 - 2.9e-12 46.8 0.0 1.5e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pescadillo_N PF06732.11 EMR65037.1 - 6e-123 409.7 0.1 1.4e-122 408.5 0.1 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.26 EMR65037.1 - 0.0002 21.7 0.0 0.0011 19.3 0.0 2.3 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EMR65037.1 - 0.0026 18.1 0.0 0.016 15.6 0.0 2.3 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Flavodoxin_5 PF12724.7 EMR65037.1 - 0.11 12.7 1.5 0.24 11.6 1.5 1.5 1 0 0 1 1 1 0 Flavodoxin domain SGT1 PF07093.11 EMR65037.1 - 3.8 5.8 13.5 7 5.0 13.5 1.3 1 0 0 1 1 1 0 SGT1 protein GMC_oxred_N PF00732.19 EMR65038.1 - 5.4e-14 52.3 0.1 3.1e-12 46.5 0.1 2.4 1 1 0 1 1 1 1 GMC oxidoreductase Abhydrolase_3 PF07859.13 EMR65040.1 - 3.1e-27 95.8 0.1 2.9e-22 79.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR65040.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_16 PF00722.21 EMR65041.1 - 1.6e-13 50.5 2.2 4e-13 49.2 2.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EMR65041.1 - 0.016 13.7 2.8 0.056 11.8 0.2 2.1 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) NAD_binding_8 PF13450.6 EMR65042.1 - 7.7e-08 32.5 0.0 7.3e-06 26.1 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR65042.1 - 5.4e-05 22.6 0.1 0.018 14.3 0.1 3.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR65042.1 - 0.00037 19.8 0.0 0.035 13.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR65042.1 - 0.0039 17.2 0.1 0.58 10.1 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EMR65042.1 - 0.043 13.9 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 EMR65043.1 - 2.5e-43 148.3 23.3 2.5e-43 148.3 23.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EMR65043.1 - 0.0038 15.6 1.3 0.0038 15.6 1.3 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family YbgT_YccB PF08173.11 EMR65043.1 - 0.31 11.2 4.8 0.3 11.3 0.8 2.7 2 0 0 2 2 2 0 Membrane bound YbgT-like protein AP_endonuc_2 PF01261.24 EMR65044.1 - 1e-33 116.6 0.0 1.3e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PT-HINT PF07591.11 EMR65045.1 - 0.0066 16.7 0.4 8 6.7 0.0 3.2 3 0 0 3 3 3 2 Pretoxin HINT domain Cellulase PF00150.18 EMR65046.1 - 1.8e-48 165.4 0.8 2.4e-48 165.0 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 EMR65048.1 - 1.1e-06 27.8 9.9 1.6e-06 27.3 9.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TENA_THI-4 PF03070.16 EMR65049.1 - 1.4e-07 31.6 0.2 0.0015 18.4 0.0 2.4 2 1 0 2 2 2 2 TENA/THI-4/PQQC family Glyco_hydro_3 PF00933.21 EMR65050.1 - 1.7e-52 178.8 0.0 2.4e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EMR65050.1 - 8e-10 39.0 0.1 1.2e-08 35.1 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain OCD_Mu_crystall PF02423.15 EMR65051.1 - 5.6e-14 51.8 0.0 1.7e-13 50.2 0.0 1.7 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EMR65051.1 - 6.6e-07 29.5 0.1 6.6e-06 26.2 0.1 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GLEYA PF10528.9 EMR65052.1 - 2.3e-16 60.0 0.2 3.5e-16 59.4 0.2 1.3 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 EMR65052.1 - 1.2e-07 31.6 0.0 1.7e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 PA14 domain HhH-GPD PF00730.25 EMR65053.1 - 1.5e-10 41.5 0.0 2.5e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EMR65053.1 - 0.00081 19.1 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Aldo_ket_red PF00248.21 EMR65054.1 - 6.5e-27 94.5 0.0 7.1e-16 58.3 0.0 2.9 1 1 1 2 2 2 2 Aldo/keto reductase family PrpF PF04303.13 EMR65055.1 - 4.3e-18 65.4 0.5 3.9e-15 55.7 0.5 3.5 2 1 0 2 2 2 2 PrpF protein Mad3_BUB1_I PF08311.12 EMR65056.1 - 3.5e-43 146.5 0.2 4.8e-43 146.1 0.2 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 EMR65056.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Pkinase PF00069.25 EMR65057.1 - 2.3e-08 33.7 0.0 3.1e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR65057.1 - 0.023 14.0 0.0 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Kinase-like PF14531.6 EMR65057.1 - 0.21 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Nop14 PF04147.12 EMR65057.1 - 0.22 9.7 15.2 0.35 9.0 15.2 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EMR65057.1 - 0.8 9.0 12.6 1.3 8.3 12.6 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EMR65057.1 - 2.9 7.2 15.8 4.9 6.5 15.8 1.3 1 0 0 1 1 1 0 SDA1 7tm_2 PF00002.24 EMR65058.1 - 4.1e-08 32.8 14.3 1.6e-07 30.9 13.7 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 EMR65058.1 - 4.3e-07 29.5 0.8 7e-07 28.8 0.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 EMR65058.1 - 1.3e-06 27.8 11.7 2.3e-06 27.0 11.7 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 EMR65058.1 - 3.3e-05 23.8 11.2 5.5e-05 23.0 11.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 CitMHS PF03600.16 EMR65058.1 - 0.0052 16.0 0.2 0.0072 15.6 0.2 1.2 1 0 0 1 1 1 1 Citrate transporter GPR_Gpa2_C PF11970.8 EMR65058.1 - 0.012 15.6 1.7 0.11 12.5 0.1 2.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term HCV_NS5a PF01506.19 EMR65058.1 - 2.2 8.3 7.7 1.4 8.9 0.3 2.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor polyprenyl_synt PF00348.17 EMR65059.1 - 5.1e-53 179.8 0.2 7.5e-53 179.2 0.2 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DRMBL PF07522.14 EMR65060.1 - 3.4e-30 104.5 0.0 7.2e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EMR65060.1 - 3.8e-05 23.3 0.0 8.7e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.24 EMR65062.1 - 2.9e-22 79.2 22.0 1.8e-15 56.8 9.7 2.9 1 1 1 2 2 2 2 Sugar (and other) transporter DUF2686 PF10887.8 EMR65062.1 - 0.024 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Fungal_trans PF04082.18 EMR65063.1 - 1.5e-09 37.3 0.1 2.7e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF72 PF01904.18 EMR65063.1 - 0.079 13.1 0.0 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF72 MFS_1 PF07690.16 EMR65065.1 - 1.3e-34 119.7 23.6 2.1e-34 119.0 23.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3649 PF12365.8 EMR65065.1 - 0.16 11.7 6.5 0.18 11.5 0.7 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Acetyltransf_5 PF13444.6 EMR65066.1 - 0.071 13.8 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_N PF08240.12 EMR65068.1 - 5.9e-26 90.5 1.9 1.7e-25 89.0 1.9 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR65068.1 - 8e-19 67.9 0.4 1.5e-18 67.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR65068.1 - 0.0011 18.3 0.3 0.002 17.4 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EMR65068.1 - 0.059 13.6 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EMR65068.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EMR65068.1 - 0.14 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EMR65068.1 - 0.19 11.0 0.1 0.33 10.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-U1 PF06220.12 EMR65069.1 - 8.1e-22 76.7 3.4 1.2e-21 76.2 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger CDT1_C PF16679.5 EMR65070.1 - 2.9e-24 85.3 0.1 2.8e-23 82.2 0.1 2.5 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain adh_short PF00106.25 EMR65071.1 - 3.3e-19 69.1 0.0 5.1e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65071.1 - 9.2e-14 51.6 0.1 1.3e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR65071.1 - 0.00016 21.6 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Acetyltransf_13 PF13880.6 EMR65071.1 - 0.04 13.9 0.0 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase tRNA-synt_2 PF00152.20 EMR65072.1 - 2.1e-77 260.3 0.0 3e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EMR65072.1 - 1.7e-20 73.3 0.0 2.5e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EMR65072.1 - 1.7e-08 34.3 0.0 4.2e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMR65072.1 - 0.02 14.3 0.1 2.9 7.3 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Cut8 PF08559.10 EMR65072.1 - 0.043 13.4 0.4 0.084 12.5 0.4 1.4 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein TMEM132D_N PF15705.5 EMR65072.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term SGL PF08450.12 EMR65073.1 - 0.00097 18.8 2.6 0.0095 15.5 1.3 2.4 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region MRJP PF03022.16 EMR65073.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Major royal jelly protein GDPD PF03009.17 EMR65074.1 - 8.8e-35 120.7 0.0 2.7e-33 115.8 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EMR65074.1 - 9.7e-05 22.7 0.3 0.00098 19.5 0.6 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EMP24_GP25L PF01105.24 EMR65075.1 - 1.4e-40 139.2 0.0 1.6e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 EMR65075.1 - 0.1 10.8 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA MBF1 PF08523.10 EMR65076.1 - 1.6e-24 86.1 2.6 3e-24 85.3 2.6 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EMR65076.1 - 1.4e-08 34.6 0.1 2.3e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EMR65076.1 - 1.3e-06 28.6 0.0 2.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 EMR65076.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Nucleopor_Nup85 PF07575.13 EMR65078.1 - 5.4e-09 35.2 0.0 0.00052 18.7 0.0 3.4 2 1 0 2 2 2 2 Nup85 Nucleoporin Leader_Trp PF08255.11 EMR65078.1 - 0.061 13.3 0.2 0.22 11.6 0.2 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide PIG-F PF06699.11 EMR65079.1 - 9.6e-64 214.8 1.2 1.3e-63 214.4 1.2 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Translin PF01997.16 EMR65079.1 - 1.6e-35 123.0 0.1 2.2e-35 122.5 0.1 1.1 1 0 0 1 1 1 1 Translin family DUF1993 PF09351.10 EMR65080.1 - 6.6e-41 140.1 0.0 7.9e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) TPR_19 PF14559.6 EMR65080.1 - 0.23 12.0 3.3 13 6.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Sdh5 PF03937.16 EMR65081.1 - 1.1e-22 79.7 0.1 3.1e-22 78.3 0.2 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Transthyretin PF00576.21 EMR65083.1 - 5.1e-36 123.7 0.1 7.7e-36 123.1 0.1 1.3 1 1 0 1 1 1 1 HIUase/Transthyretin family Big_1 PF02369.16 EMR65083.1 - 0.045 13.8 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Sacchrp_dh_C PF16653.5 EMR65084.1 - 4.5e-64 217.1 0.0 1.4e-61 208.9 0.0 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EMR65084.1 - 7e-22 78.1 0.1 1e-21 77.6 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMR65084.1 - 5.9e-09 36.1 0.2 7.7e-08 32.5 0.2 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EMR65084.1 - 4.6e-05 23.4 0.1 6.9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EMR65084.1 - 0.00026 21.5 0.1 0.00053 20.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 EMR65084.1 - 0.03 15.0 0.1 0.059 14.0 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMR65084.1 - 0.14 12.6 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 EMR65086.1 - 4.8e-23 81.6 0.0 6.5e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65086.1 - 1.3e-12 47.8 0.0 1.6e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR65086.1 - 0.00011 21.7 0.0 0.0002 20.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR65086.1 - 0.00078 19.4 0.0 0.0021 18.0 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR65086.1 - 0.021 14.2 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 EMR65086.1 - 0.021 14.7 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 KR domain 3HCDH_N PF02737.18 EMR65086.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EMR65086.1 - 0.16 12.6 0.0 2 9.0 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Aft1_HRR PF11787.8 EMR65087.1 - 1.1e-15 58.6 4.6 1.1e-15 58.6 4.6 3.5 3 2 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.21 EMR65087.1 - 3.8e-13 49.3 6.5 6.4e-13 48.6 6.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMR65087.1 - 1.2e-06 28.4 6.4 2.6e-06 27.4 6.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMR65087.1 - 0.00064 20.2 2.7 0.00064 20.2 2.7 2.1 3 0 0 3 3 3 1 bZIP Maf transcription factor HALZ PF02183.18 EMR65087.1 - 0.058 13.6 0.2 0.1 12.9 0.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF334 PF03904.13 EMR65087.1 - 0.32 10.5 1.9 0.49 9.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Macoilin PF09726.9 EMR65087.1 - 0.37 9.3 7.1 0.45 9.0 7.1 1.2 1 0 0 1 1 1 0 Macoilin family NpwBP PF12622.7 EMR65087.1 - 3.8 8.3 11.0 1.9 9.3 2.9 2.9 2 0 0 2 2 2 0 mRNA biogenesis factor Abhydrolase_3 PF07859.13 EMR65088.1 - 4e-42 144.4 0.0 5.1e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR65088.1 - 5e-07 29.0 0.0 1.6e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 EMR65088.1 - 0.069 12.8 0.1 0.37 10.4 0.1 1.9 1 1 0 1 1 1 0 Putative esterase Say1_Mug180 PF10340.9 EMR65088.1 - 0.14 11.0 0.0 0.38 9.6 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Ctr PF04145.15 EMR65089.1 - 8.1e-20 71.9 0.8 1.7e-19 70.9 0.8 1.5 1 1 0 1 1 1 1 Ctr copper transporter family PNP_UDP_1 PF01048.20 EMR65090.1 - 1.7e-13 50.4 0.2 2.6e-13 49.8 0.2 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 EMR65090.1 - 2.4e-09 37.3 0.2 4.5e-09 36.5 0.2 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMR65090.1 - 0.00015 22.2 0.0 0.00027 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EMR65090.1 - 0.0012 18.5 0.5 0.0032 17.2 0.5 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMR65090.1 - 0.0037 17.8 0.0 0.026 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMR65090.1 - 0.0055 17.0 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMR65090.1 - 0.012 16.2 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EMR65090.1 - 0.027 13.8 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin GP52 PF17468.2 EMR65090.1 - 0.057 13.6 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Phage gene product 52 RNA_helicase PF00910.22 EMR65090.1 - 0.2 12.1 0.2 0.77 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Ferric_reduct PF01794.19 EMR65091.1 - 2.1e-14 53.7 15.8 2.1e-14 53.7 15.8 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMR65091.1 - 1.1e-10 41.9 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR65091.1 - 4e-07 30.1 0.0 8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain CoA_trans PF01144.23 EMR65091.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Coenzyme A transferase DUF4405 PF14358.6 EMR65091.1 - 0.7 10.5 19.1 0.43 11.2 2.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) eIF3_subunit PF08597.10 EMR65092.1 - 0.53 10.2 9.8 1.1 9.2 9.8 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1682 PF07946.14 EMR65092.1 - 1.8 7.7 10.5 3.3 6.8 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PTPA PF03095.15 EMR65093.1 - 3.7e-85 286.0 1.6 4.3e-85 285.8 1.6 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.21 EMR65094.1 - 1.6e-12 48.0 0.0 3.7e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EMR65094.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Anp1 PF03452.14 EMR65095.1 - 4.1e-108 360.8 0.0 4.8e-108 360.6 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EMR65095.1 - 0.036 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 NAD_kinase PF01513.21 EMR65096.1 - 1.6e-80 270.5 0.0 2.6e-80 269.7 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Aldedh PF00171.22 EMR65098.1 - 1.1e-136 456.0 0.0 1.3e-136 455.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family VWA PF00092.28 EMR65099.1 - 0.099 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Peptidase_S10 PF00450.22 EMR65100.1 - 7.5e-81 272.7 0.8 5.3e-80 269.9 0.8 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Ald_Xan_dh_C2 PF02738.18 EMR65101.1 - 1.4e-202 674.0 0.0 1.9e-202 673.6 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EMR65101.1 - 6.2e-48 162.8 0.0 1.2e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 EMR65101.1 - 8.8e-30 103.3 0.0 2e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EMR65101.1 - 1.1e-29 102.3 0.0 2.4e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 EMR65101.1 - 1.7e-28 98.8 0.0 5.2e-28 97.2 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 EMR65101.1 - 6.6e-08 32.4 1.9 8.4e-08 32.1 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain PPR_2 PF13041.6 EMR65102.1 - 6.4e-16 58.3 0.0 0.00046 20.3 0.0 4.5 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 EMR65102.1 - 1.1e-12 47.3 6.6 8.6e-05 22.5 0.0 4.9 5 1 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 EMR65102.1 - 2.7e-08 33.4 2.9 0.053 13.2 0.1 3.8 3 1 0 3 3 3 3 PPR repeat PPR_3 PF13812.6 EMR65102.1 - 9.7e-07 28.8 0.1 0.054 13.6 0.0 4.5 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EMR65102.1 - 0.003 17.0 0.1 0.018 14.5 0.1 2.2 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP TFIIA_gamma_N PF02268.16 EMR65102.1 - 0.11 12.5 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain PSDC PF12588.8 EMR65103.1 - 1e-28 100.1 0.1 1.9e-28 99.2 0.1 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EMR65103.1 - 5.6e-24 84.8 0.0 8.7e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MRP-S25 PF13741.6 EMR65104.1 - 3e-67 226.6 9.9 2.2e-61 207.4 4.7 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EMR65104.1 - 4e-08 33.6 5.8 5.2e-08 33.2 4.2 2.1 1 1 1 2 2 2 1 Mitochondrial ribosomal protein S23 Cullin PF00888.22 EMR65106.1 - 1.8e-23 83.0 0.0 3.1e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EMR65106.1 - 2.6e-22 79.1 0.0 7.1e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Csm1 PF12539.8 EMR65107.1 - 1.1e-32 112.5 0.0 3.2e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Taxilin PF09728.9 EMR65107.1 - 0.00012 21.4 8.6 0.00022 20.5 8.6 1.4 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Rootletin PF15035.6 EMR65107.1 - 0.00056 20.0 13.4 0.0014 18.7 13.4 1.6 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Filament PF00038.21 EMR65107.1 - 0.0011 18.6 10.4 0.0026 17.4 10.4 1.6 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 EMR65107.1 - 0.01 14.8 12.6 0.019 13.8 12.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF5094 PF17015.5 EMR65107.1 - 0.022 14.9 0.0 0.022 14.9 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5094) DUF4201 PF13870.6 EMR65107.1 - 0.027 14.2 8.2 0.052 13.3 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TraG_N PF07916.11 EMR65107.1 - 0.078 11.8 5.5 0.1 11.5 5.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region FapA PF03961.13 EMR65107.1 - 0.091 11.4 3.6 0.16 10.5 3.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A MMPL PF03176.15 EMR65107.1 - 0.12 11.3 7.5 0.19 10.6 7.5 1.2 1 0 0 1 1 1 0 MMPL family CRR7 PF12095.8 EMR65107.1 - 0.14 12.6 2.1 0.44 11.0 2.1 1.9 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 V_ATPase_I PF01496.19 EMR65107.1 - 0.23 9.4 7.1 0.31 8.9 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TACC_C PF05010.14 EMR65107.1 - 0.3 10.8 14.7 1.3 8.7 14.3 2.2 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FUSC PF04632.12 EMR65107.1 - 0.69 8.4 8.1 1.1 7.7 8.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 EMR65107.1 - 0.97 8.5 10.9 1.5 7.9 10.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EMR65107.1 - 1.1 8.4 5.6 1.7 7.8 5.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Prominin PF05478.11 EMR65107.1 - 1.2 7.0 4.7 1.7 6.5 4.7 1.1 1 0 0 1 1 1 0 Prominin CorA PF01544.18 EMR65107.1 - 1.3 8.3 4.4 2.8 7.2 4.4 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 EMR65107.1 - 1.5 8.9 17.5 0.24 11.5 8.6 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EMR65107.1 - 1.8 9.2 10.3 1 10.0 3.2 2.5 1 1 2 3 3 3 0 Initiation control protein YabA TEX13 PF15186.6 EMR65107.1 - 4 7.1 11.1 8.8 6.0 11.1 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF3138 PF11336.8 EMR65107.1 - 4.7 5.7 12.5 7 5.1 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CENP-H PF05837.12 EMR65107.1 - 7.1 7.1 23.4 0.27 11.6 10.0 2.8 2 1 1 3 3 2 0 Centromere protein H (CENP-H) DHR10 PF18595.1 EMR65107.1 - 7.7 6.6 24.3 9.4 6.3 16.5 3.3 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain APH PF01636.23 EMR65108.1 - 3e-41 141.9 2.9 3e-41 141.9 2.9 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EMR65108.1 - 1e-05 25.0 0.6 3.9e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 EMR65108.1 - 0.0076 15.9 0.0 0.016 14.8 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Cys_Met_Meta_PP PF01053.20 EMR65109.1 - 3.3e-134 447.2 0.0 3.8e-134 447.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMR65109.1 - 2.6e-06 26.6 0.0 2.3e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EMR65109.1 - 2.5e-05 23.0 0.1 6.5e-05 21.6 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 EMR65109.1 - 0.0019 17.6 0.0 0.0063 15.9 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EMR65109.1 - 0.057 12.7 0.1 0.24 10.7 0.1 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase AAA PF00004.29 EMR65110.1 - 3.3e-38 131.1 0.0 5.3e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMR65110.1 - 5e-09 35.8 0.1 1e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EMR65110.1 - 5e-06 27.0 0.1 0.00042 20.7 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EMR65110.1 - 7.2e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EMR65110.1 - 7.8e-06 26.0 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMR65110.1 - 1.3e-05 25.2 0.1 0.00019 21.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMR65110.1 - 5.9e-05 23.4 0.1 0.0039 17.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EMR65110.1 - 7.3e-05 22.9 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 EMR65110.1 - 0.00053 19.4 0.0 0.77 9.1 0.0 2.3 1 1 1 2 2 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 EMR65110.1 - 0.00099 18.5 0.1 0.0021 17.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EMR65110.1 - 0.0017 18.6 0.0 0.0038 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMR65110.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EMR65110.1 - 0.0037 17.6 0.0 0.0092 16.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 EMR65110.1 - 0.0039 16.8 0.4 0.042 13.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EMR65110.1 - 0.0044 16.9 0.0 0.014 15.3 0.0 1.9 2 1 0 2 2 1 1 NACHT domain Sigma54_activat PF00158.26 EMR65110.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EMR65110.1 - 0.012 15.5 0.0 0.087 12.7 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EMR65110.1 - 0.013 14.7 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 EMR65110.1 - 0.013 16.0 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EMR65110.1 - 0.016 14.3 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EMR65110.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMR65110.1 - 0.022 14.7 0.1 0.067 13.1 0.0 1.7 1 1 1 2 2 2 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EMR65110.1 - 0.025 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 EMR65110.1 - 0.026 13.7 0.1 0.1 11.8 0.0 1.9 2 1 0 2 2 2 0 TIP49 P-loop domain Bac_DnaA PF00308.18 EMR65110.1 - 0.046 13.5 0.0 0.087 12.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_28 PF13521.6 EMR65110.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EMR65110.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 EMR65110.1 - 0.058 13.9 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EMR65110.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EMR65110.1 - 0.066 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EMR65110.1 - 0.072 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EMR65110.1 - 0.096 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Oxidored_nitro PF00148.19 EMR65110.1 - 0.1 11.3 0.0 0.72 8.5 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Viral_helicase1 PF01443.18 EMR65110.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase P34-Arc PF04045.14 EMR65111.1 - 1.5e-107 358.8 0.7 1.8e-107 358.5 0.7 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Radical_SAM PF04055.21 EMR65111.1 - 0.11 12.8 0.1 0.33 11.3 0.1 1.8 2 0 0 2 2 2 0 Radical SAM superfamily WD40 PF00400.32 EMR65112.1 - 8.2e-48 159.4 21.0 6.2e-06 26.9 0.2 12.2 12 1 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 EMR65112.1 - 6.7e-18 65.0 1.0 1.4e-17 63.9 1.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EMR65112.1 - 9.7e-17 61.1 8.7 0.062 13.6 0.0 9.7 5 2 6 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR65112.1 - 3.6e-07 29.5 0.2 0.14 11.1 0.0 4.8 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EMR65112.1 - 2.1e-05 23.4 3.2 0.17 10.5 0.1 5.6 5 2 1 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EMR65112.1 - 0.00074 18.9 0.0 12 5.1 0.0 3.6 4 0 0 4 4 4 3 WD40-like domain RAB3GAP2_N PF14655.6 EMR65112.1 - 0.039 13.2 0.2 1.8 7.7 0.0 3.1 3 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 EMR65112.1 - 0.077 11.7 4.8 0.49 9.1 0.3 3.9 3 1 0 4 4 4 0 Nup133 N terminal like Questin_oxidase PF14027.6 EMR65113.1 - 1.8e-93 313.8 0.0 2.2e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like zf-C2H2 PF00096.26 EMR65114.1 - 0.00063 20.1 4.1 0.15 12.6 0.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR65114.1 - 0.0082 16.9 4.0 3.1 8.9 0.2 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-ribbon_3 PF13248.6 EMR65114.1 - 0.036 13.5 0.1 0.073 12.5 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 EMR65114.1 - 0.082 13.4 0.6 0.92 10.1 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 EMR65114.1 - 0.26 11.4 0.2 0.26 11.4 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain SMC_N PF02463.19 EMR65115.1 - 1.3e-67 227.5 37.0 1.5e-66 224.0 37.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMR65115.1 - 2.1e-24 86.0 0.0 7.5e-24 84.3 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EMR65115.1 - 9.8e-13 48.6 0.2 5.9e-05 23.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Tektin PF03148.14 EMR65115.1 - 0.00014 20.7 17.9 0.00014 20.7 17.9 5.8 3 2 3 6 6 6 1 Tektin family AAA_29 PF13555.6 EMR65115.1 - 0.00082 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 EMR65115.1 - 0.0015 18.7 18.4 0.0015 18.7 18.4 9.2 4 2 3 8 8 6 2 Tropomyosin like DUF4201 PF13870.6 EMR65115.1 - 0.0016 18.2 16.4 0.0016 18.2 16.4 7.5 4 2 3 7 7 7 3 Domain of unknown function (DUF4201) DivIC PF04977.15 EMR65115.1 - 0.0037 17.0 2.5 0.0037 17.0 2.5 11.8 7 4 6 13 13 12 1 Septum formation initiator Laminin_II PF06009.12 EMR65115.1 - 0.0061 16.6 2.3 0.0061 16.6 2.3 8.9 2 2 7 9 9 8 2 Laminin Domain II DUF4164 PF13747.6 EMR65115.1 - 0.023 14.9 0.6 0.023 14.9 0.6 8.2 6 2 2 8 8 7 0 Domain of unknown function (DUF4164) AAA_22 PF13401.6 EMR65115.1 - 0.43 10.9 2.5 25 5.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EMR65115.1 - 1.9 9.0 0.0 1.9 9.0 0.0 6.9 4 2 0 4 4 2 0 ABC transporter Ribosomal_S26e PF01283.19 EMR65116.1 - 2e-52 176.2 9.6 2.3e-52 176.0 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EMR65116.1 - 0.017 15.1 0.4 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 EMR65116.1 - 0.22 11.3 2.3 0.24 11.2 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) Isochorismatase PF00857.20 EMR65117.1 - 2.4e-31 109.3 0.0 5.5e-31 108.1 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family ubiquitin PF00240.23 EMR65118.1 - 4.5e-34 116.0 0.6 7.8e-34 115.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EMR65118.1 - 5.7e-26 90.4 1.7 5.7e-26 90.4 1.7 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EMR65118.1 - 2.6e-16 59.2 0.7 4.8e-16 58.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMR65118.1 - 2.6e-05 24.6 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMR65118.1 - 0.00071 19.7 0.7 0.0016 18.5 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EMR65118.1 - 0.0047 17.3 1.0 0.0075 16.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EMR65118.1 - 0.0054 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EMR65118.1 - 0.013 16.1 0.9 0.018 15.6 0.9 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EMR65118.1 - 0.02 14.9 1.0 5.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain ELYS PF13934.6 EMR65119.1 - 4e-66 223.2 3.6 4.7e-66 222.9 3.6 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SUIM_assoc PF16619.5 EMR65119.1 - 0.0058 16.7 1.1 0.01 15.9 1.1 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 FAD_binding_3 PF01494.19 EMR65121.1 - 5.1e-69 233.2 2.0 1.9e-68 231.3 2.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR65121.1 - 0.0026 17.1 0.1 0.0047 16.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EMR65121.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Nop PF01798.18 EMR65122.1 - 3.4e-82 275.4 0.2 5.8e-82 274.6 0.2 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EMR65122.1 - 4.6e-19 68.6 0.4 2.1e-18 66.4 0.4 2.3 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF4257 PF14074.6 EMR65122.1 - 0.035 14.3 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) RNA_polI_A34 PF08208.11 EMR65122.1 - 0.46 10.5 18.3 0.87 9.6 18.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 EMR65122.1 - 2.2 8.1 13.7 4.7 7.0 13.7 1.5 1 0 0 1 1 1 0 Coilin N-terminus DUF3408 PF11888.8 EMR65122.1 - 6.6 6.9 12.8 60 3.8 9.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3408) adh_short PF00106.25 EMR65123.1 - 5.3e-39 133.7 3.4 7e-39 133.3 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65123.1 - 5.1e-28 98.2 0.4 6.9e-28 97.8 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR65123.1 - 1.2e-12 48.2 0.8 1.6e-12 47.7 0.8 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR65123.1 - 2e-05 23.9 0.4 2.4e-05 23.6 0.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMR65123.1 - 7.4e-05 22.3 0.1 0.0012 18.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EMR65123.1 - 0.015 15.4 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Endonuc-FokI_C PF09254.11 EMR65123.1 - 0.17 11.1 0.0 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 Restriction endonuclease FokI, C terminal NAD_binding_6 PF08030.12 EMR65124.1 - 0.0065 16.6 0.0 0.008 16.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain p450 PF00067.22 EMR65125.1 - 3.9e-41 141.3 0.0 5.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SLD3 PF08639.10 EMR65127.1 - 4.2e-89 299.7 10.9 5.8e-89 299.3 10.9 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 MFS_1 PF07690.16 EMR65128.1 - 4.1e-25 88.5 35.0 5.9e-25 87.9 35.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65128.1 - 2.1e-09 36.8 15.9 2.1e-09 36.8 15.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1072 PF06380.11 EMR65128.1 - 1.8 8.5 5.5 2.2 8.2 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) PFK PF00365.20 EMR65129.1 - 5.3e-187 619.9 0.1 6.5e-105 350.5 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase BRCT PF00533.26 EMR65130.1 - 3.6e-06 27.3 0.1 5.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LCE6A PF15858.5 EMR65130.1 - 0.019 15.7 0.7 0.043 14.6 0.7 1.5 1 0 0 1 1 1 0 Late cornified envelope protein 6A family Sigma70_ner PF04546.13 EMR65130.1 - 1.3 8.8 10.0 0.1 12.4 3.6 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Roughex PF06020.11 EMR65130.1 - 1.3 8.0 9.0 2.1 7.3 9.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein p450 PF00067.22 EMR65131.1 - 1.4e-44 152.7 0.0 1.8e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 VPS11_C PF12451.8 EMR65131.1 - 0.0055 16.9 0.0 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal KR PF08659.10 EMR65132.1 - 1.6e-53 181.3 0.2 2.7e-53 180.5 0.2 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 EMR65132.1 - 1.7e-18 68.0 0.0 5.3e-17 63.1 0.0 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EMR65132.1 - 2.6e-17 63.4 0.0 8e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EMR65132.1 - 2.4e-12 47.0 0.1 8.3e-12 45.2 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR65132.1 - 3.5e-10 39.7 0.8 7.3e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 EMR65132.1 - 5e-10 39.5 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR65132.1 - 3.1e-09 37.0 0.4 7.9e-09 35.8 0.0 1.9 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EMR65132.1 - 8.5e-09 36.0 0.1 6.1e-08 33.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR65132.1 - 6.8e-08 33.1 0.0 3e-07 31.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR65132.1 - 5.5e-07 29.5 0.0 2.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.17 EMR65132.1 - 0.00017 21.3 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_N PF08240.12 EMR65132.1 - 0.023 14.6 0.0 0.069 13.0 0.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain NmrA PF05368.13 EMR65132.1 - 0.096 12.2 0.2 0.93 9.0 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family DUF3824 PF12868.7 EMR65133.1 - 0.00065 20.4 1.6 0.0015 19.3 1.6 1.5 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) Autoind_bind PF03472.15 EMR65133.1 - 0.054 13.0 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 Autoinducer binding domain Serglycin PF04360.12 EMR65133.1 - 0.076 13.0 4.0 1.8 8.5 2.9 2.3 2 0 0 2 2 2 0 Serglycin ketoacyl-synt PF00109.26 EMR65134.1 - 5.3e-65 219.5 0.0 8.4e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EMR65134.1 - 2.1e-46 158.9 0.1 3.6e-46 158.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR65134.1 - 4.3e-40 136.4 0.0 9.9e-40 135.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR65134.1 - 4.2e-14 52.9 0.0 2.1e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 EMR65134.1 - 0.0025 17.6 1.7 0.0039 17.0 0.4 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EMR65134.1 - 0.0032 16.9 0.1 0.0085 15.5 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain baeRF_family3 PF18845.1 EMR65134.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 BPD_transp_1 PF00528.22 EMR65135.1 - 0.003 17.3 2.7 0.0051 16.6 2.5 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ADH_zinc_N PF00107.26 EMR65137.1 - 6.9e-26 90.8 0.1 1.2e-25 90.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR65137.1 - 1.7e-16 61.5 0.0 3.6e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR65137.1 - 1.3e-07 31.4 0.1 6.5e-07 29.2 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_2 PF03446.15 EMR65138.1 - 7.8e-25 87.9 0.3 1.2e-24 87.2 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMR65138.1 - 3.7e-10 40.1 0.1 7.3e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EMR65138.1 - 0.00045 20.7 0.1 0.0024 18.4 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMR65138.1 - 0.0033 17.5 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EMR65138.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PH_10 PF15411.6 EMR65139.1 - 1.5e-42 144.7 0.4 3.1e-42 143.7 0.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EMR65139.1 - 3.2e-27 96.0 0.1 5.9e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 EMR65139.1 - 1.2e-23 83.2 0.0 1e-22 80.2 0.0 2.3 2 0 0 2 2 2 1 CDC24 Calponin PB1 PF00564.24 EMR65139.1 - 1.4e-09 37.8 0.0 3.6e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 PB1 domain DUF4071 PF13281.6 EMR65139.1 - 0.01 14.9 0.0 0.032 13.3 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4071) PH PF00169.29 EMR65139.1 - 0.097 13.2 0.2 0.22 12.1 0.2 1.5 1 0 0 1 1 1 0 PH domain Pkinase_Tyr PF07714.17 EMR65140.1 - 0.24 10.7 0.0 8.4 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase EHN PF06441.12 EMR65142.1 - 5.8e-29 100.6 0.5 9.4e-29 100.0 0.5 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMR65142.1 - 4.9e-06 26.4 0.0 6.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR65142.1 - 0.0012 19.5 0.1 0.0021 18.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_3_C PF01915.22 EMR65144.1 - 1.8e-45 155.4 0.0 2.9e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EMR65144.1 - 1e-21 76.8 0.1 1.8e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 EMR65144.1 - 3.8e-21 75.8 0.1 6.2e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Epimerase PF01370.21 EMR65145.1 - 1.4e-18 67.2 0.0 4.3e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR65145.1 - 1.3e-16 60.5 0.0 3.3e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMR65145.1 - 1.6e-14 54.2 0.0 2.4e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMR65145.1 - 5e-13 48.8 0.0 8.1e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 EMR65145.1 - 1.1e-08 35.0 0.0 2.8e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMR65145.1 - 2e-07 30.4 0.0 2.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMR65145.1 - 5.2e-06 26.1 0.0 8.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMR65145.1 - 0.00041 19.9 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR65145.1 - 0.0015 18.5 0.4 0.026 14.5 0.4 2.2 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EMR65145.1 - 0.0051 16.0 0.1 0.0081 15.3 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_2 PF03446.15 EMR65145.1 - 0.056 13.6 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.20 EMR65145.1 - 0.11 12.6 0.1 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GST_C PF00043.25 EMR65146.1 - 8.1e-12 45.2 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR65146.1 - 3.2e-10 39.9 0.1 1.2e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR65146.1 - 9.8e-08 32.1 0.0 2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMR65146.1 - 7.1e-07 29.5 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR65146.1 - 0.00044 20.6 0.0 0.00077 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DIOX_N PF14226.6 EMR65147.1 - 7.4e-15 55.7 0.0 7.8e-14 52.4 0.0 2.3 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR65147.1 - 1.8e-08 34.8 0.0 4.1e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DHDPS PF00701.22 EMR65148.1 - 5.8e-46 156.5 0.0 6.6e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 EMR65148.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase RNase_H PF00075.24 EMR65149.1 - 4.1e-23 82.2 0.1 8.4e-23 81.1 0.1 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EMR65149.1 - 0.0011 18.8 0.1 0.027 14.3 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like CENP-B_dimeris PF09026.10 EMR65149.1 - 0.056 13.8 5.4 0.1 13.0 5.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MFS_1 PF07690.16 EMR65150.1 - 5.2e-19 68.4 26.9 1.5e-16 60.3 23.7 3.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Med18 PF09637.10 EMR65151.1 - 1.2e-30 107.2 0.0 1.4e-30 107.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Sugar_tr PF00083.24 EMR65152.1 - 9.3e-36 123.6 20.4 9.2e-31 107.2 6.9 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EMR65152.1 - 4.3e-08 32.5 25.5 8.5e-06 24.9 6.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily XPC-binding PF09280.11 EMR65152.1 - 0.037 13.8 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 XPC-binding domain p450 PF00067.22 EMR65153.1 - 2.2e-43 148.7 0.0 2.9e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Snf7 PF03357.21 EMR65154.1 - 2.7e-35 121.5 7.7 3e-35 121.4 7.7 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.6 EMR65154.1 - 0.041 13.6 10.6 0.05 13.3 8.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) BLOC1_2 PF10046.9 EMR65154.1 - 0.14 12.4 6.9 0.068 13.5 2.5 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TssC PF17541.2 EMR65154.1 - 0.16 10.8 2.9 0.19 10.5 2.9 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB FapA PF03961.13 EMR65154.1 - 0.16 10.5 4.3 0.21 10.2 4.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 EMR65154.1 - 0.22 11.5 13.5 1.8 8.6 0.0 3.6 2 1 1 3 3 3 0 Prefoldin subunit TMPIT PF07851.13 EMR65154.1 - 0.37 10.0 6.3 0.6 9.3 6.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF3584 PF12128.8 EMR65154.1 - 0.39 8.2 11.5 0.48 7.9 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2703 PF10865.8 EMR65154.1 - 0.45 10.7 3.0 20 5.4 0.1 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF2703) IZUMO PF15005.6 EMR65154.1 - 0.46 11.0 2.8 0.83 10.2 2.8 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated NPV_P10 PF05531.12 EMR65154.1 - 0.5 10.9 3.7 0.64 10.5 1.7 2.3 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF720 PF05302.11 EMR65154.1 - 0.82 9.5 6.1 1.2 9.0 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF720) FadA PF09403.10 EMR65154.1 - 0.84 10.2 10.0 0.48 10.9 6.5 2.3 2 1 0 2 2 2 0 Adhesion protein FadA KxDL PF10241.9 EMR65154.1 - 1.2 9.5 10.3 6.1 7.2 1.0 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 EMR65154.1 - 2.5 8.2 12.6 9.8 6.2 2.7 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EMR65154.1 - 2.8 8.1 9.0 3.1 8.0 5.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mitoc_mL59 PF18126.1 EMR65154.1 - 4.1 7.7 7.4 6.9 7.0 7.4 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Hydantoinase_B PF02538.14 EMR65155.1 - 6.1e-197 655.1 2.3 3.2e-108 362.4 0.0 2.2 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMR65155.1 - 9.6e-104 346.7 0.4 1.9e-103 345.8 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMR65155.1 - 2.8e-47 160.7 0.7 4.3e-45 153.6 0.0 3.0 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 EMR65155.1 - 0.042 13.5 0.1 0.08 12.6 0.1 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Aminotran_1_2 PF00155.21 EMR65156.1 - 8.1e-56 189.7 0.0 2.1e-49 168.6 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II GST_C PF00043.25 EMR65158.1 - 6.2e-09 36.0 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMR65158.1 - 1e-07 32.2 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR65158.1 - 1.9e-06 27.8 0.0 8.4e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR65158.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR65158.1 - 0.00027 21.3 0.0 0.0005 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMR65158.1 - 0.002 18.4 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain WD40 PF00400.32 EMR65159.1 - 6.6e-29 99.5 4.5 2.3e-05 25.0 0.1 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 EMR65159.1 - 2.5e-12 46.5 0.4 7.3e-12 45.0 0.4 1.9 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EMR65159.1 - 1.2e-08 35.1 0.1 0.14 12.4 0.1 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EMR65159.1 - 1.5e-07 31.1 0.0 4.5e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EMR65159.1 - 0.2 10.2 0.6 1.1 7.8 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 aGPT-Pplase1 PF18723.1 EMR65161.1 - 0.13 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Glu-tRNAGln PF02686.15 EMR65163.1 - 3.5e-07 30.4 0.0 8.6e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit Creb_binding PF09030.10 EMR65163.1 - 0.2 12.3 5.3 0.092 13.4 3.2 1.6 2 0 0 2 2 2 0 Creb binding V-SNARE PF05008.15 EMR65164.1 - 4e-22 78.4 2.6 4e-22 78.4 2.6 2.3 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EMR65164.1 - 3e-17 62.7 4.0 3e-17 62.7 4.0 2.3 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EMR65164.1 - 1.1e-05 25.2 1.8 1.6e-05 24.7 0.3 2.1 2 1 0 2 2 2 1 Sec20 Fusion_gly PF00523.18 EMR65164.1 - 0.0023 16.3 1.6 0.0042 15.4 0.4 1.8 2 0 0 2 2 2 1 Fusion glycoprotein F0 FAM76 PF16046.5 EMR65164.1 - 0.022 14.1 0.3 0.022 14.1 0.3 1.6 2 0 0 2 2 2 0 FAM76 protein SNARE PF05739.19 EMR65164.1 - 0.068 13.2 0.7 0.068 13.2 0.7 3.2 4 0 0 4 4 4 0 SNARE domain Birna_RdRp PF04197.12 EMR65164.1 - 0.18 10.1 0.5 0.2 9.9 0.5 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Synaptobrevin PF00957.21 EMR65164.1 - 0.42 10.5 5.1 0.98 9.2 4.5 2.0 1 1 0 1 1 1 0 Synaptobrevin YqjK PF13997.6 EMR65164.1 - 0.71 10.2 5.7 2.3 8.5 0.1 3.0 4 0 0 4 4 4 0 YqjK-like protein FUSC PF04632.12 EMR65164.1 - 0.76 8.2 8.3 0.21 10.1 4.7 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family Prominin PF05478.11 EMR65164.1 - 1.3 6.9 5.2 12 3.7 4.0 1.9 1 1 1 2 2 2 0 Prominin Exonuc_VII_L PF02601.15 EMR65164.1 - 6.1 6.3 12.4 37 3.8 12.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit NUC173 PF08161.12 EMR65165.1 - 1.5e-81 272.9 0.4 4.4e-77 258.4 0.0 4.1 5 0 0 5 5 5 2 NUC173 domain NEMO PF11577.8 EMR65165.1 - 0.041 13.9 0.7 0.52 10.4 0.1 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Vac14_Fab1_bd PF12755.7 EMR65165.1 - 0.089 13.4 0.1 15 6.3 0.0 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EMR65165.1 - 0.099 13.0 5.2 0.54 10.7 0.4 4.2 4 1 0 4 4 4 0 HEAT repeats HEAT PF02985.22 EMR65165.1 - 0.16 12.3 1.4 31 5.2 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat Nucleo_P87 PF07267.11 EMR65165.1 - 0.91 8.3 5.0 0.11 11.3 0.5 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.6 EMR65165.1 - 8.2 6.1 8.9 3.8 7.2 5.4 2.3 2 0 0 2 2 2 0 FAM176 family SNAP PF14938.6 EMR65166.1 - 8.2e-118 392.9 7.9 9.2e-118 392.7 7.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EMR65166.1 - 6.9e-07 29.5 7.3 0.0015 18.8 0.5 3.5 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMR65166.1 - 1.7e-05 24.5 13.9 0.21 11.8 1.2 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMR65166.1 - 0.0019 18.1 6.6 0.77 9.9 0.0 5.3 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMR65166.1 - 0.0045 17.5 9.5 33 5.4 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMR65166.1 - 0.039 14.2 9.9 9.7 6.7 0.8 4.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMR65166.1 - 0.44 10.4 17.9 1.6 8.7 1.4 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMR65166.1 - 3.6 8.3 14.1 5.8 7.7 2.3 4.9 2 2 4 6 6 6 0 Tetratricopeptide repeat RasGEF PF00617.19 EMR65167.1 - 6.3e-46 156.8 0.2 1e-45 156.1 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EMR65167.1 - 5.2e-11 42.7 0.1 1.8e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 EMR65167.1 - 1.2e-05 25.0 0.0 2.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Ras family DUF726 PF05277.12 EMR65168.1 - 3.2e-108 361.7 0.1 5.3e-108 361.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DHR10 PF18595.1 EMR65168.1 - 0.82 9.7 7.1 1.9 8.6 7.1 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain FAD_binding_4 PF01565.23 EMR65170.1 - 6.9e-22 77.7 0.3 1.3e-21 76.8 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Acetyltransf_8 PF13523.6 EMR65171.1 - 1.6e-36 125.2 0.6 2.6e-36 124.5 0.6 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NmrA PF05368.13 EMR65172.1 - 5.7e-21 75.1 0.0 9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR65172.1 - 3.4e-10 40.1 0.1 5.7e-08 32.9 0.0 2.7 2 1 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 EMR65172.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mito_carr PF00153.27 EMR65173.1 - 3.5e-40 135.8 8.6 4.2e-16 58.6 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FMO-like PF00743.19 EMR65176.1 - 2.6e-11 42.6 0.0 4.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR65176.1 - 9.5e-10 38.2 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR65176.1 - 2e-09 37.1 0.0 7.1e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMR65176.1 - 7.1e-09 35.3 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR65176.1 - 8e-06 26.0 0.0 8.8e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR65176.1 - 0.0002 20.7 0.0 0.00055 19.2 0.0 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EMR65176.1 - 0.04 13.5 0.1 0.6 9.6 0.1 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR65176.1 - 0.081 12.0 0.1 11 5.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 EMR65177.1 - 3.3e-23 82.2 37.4 3.3e-23 82.2 37.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65177.1 - 7.5e-14 51.4 26.9 1.2e-13 50.8 26.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans_2 PF11951.8 EMR65178.1 - 2e-05 23.6 0.2 3.1e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arg_decarb_HB PF17810.1 EMR65178.1 - 0.063 13.5 0.1 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain Zn_clus PF00172.18 EMR65179.1 - 5.1e-07 29.7 7.2 9.1e-07 28.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR65179.1 - 0.00049 19.2 0.0 0.00077 18.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MscS_TM PF12794.7 EMR65179.1 - 0.029 13.2 0.2 0.052 12.4 0.2 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 K_channel_TID PF07941.11 EMR65179.1 - 3.1 8.3 4.4 1.7 9.2 0.7 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_hydro_18 PF00704.28 EMR65180.1 - 4.5e-82 276.3 0.0 5.2e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DEAD PF00270.29 EMR65181.1 - 4.7e-42 143.7 0.0 7.1e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR65181.1 - 3e-27 95.2 0.6 1.2e-26 93.2 0.3 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR65181.1 - 0.00071 19.6 0.6 0.0013 18.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EMR65181.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Spt20 PF12090.8 EMR65181.1 - 4.8 6.7 13.9 8.2 6.0 13.9 1.3 1 0 0 1 1 1 0 Spt20 family adh_short PF00106.25 EMR65182.1 - 8.1e-29 100.5 0.0 1.2e-21 77.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65182.1 - 9.6e-15 54.8 0.0 3.5e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR65182.1 - 1.5e-06 28.2 0.1 6.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMR65182.1 - 0.022 14.2 0.0 0.079 12.4 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GatB_N PF02934.15 EMR65183.1 - 7.9e-97 323.9 0.0 9.7e-97 323.6 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EMR65183.1 - 6.5e-10 39.1 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 GatB domain Glyco_hydro_31 PF01055.26 EMR65184.1 - 7.6e-85 285.7 5.3 7.6e-85 285.7 5.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 EMR65184.1 - 1.8e-05 24.9 0.0 4.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) GP67 PF17634.2 EMR65184.1 - 1.3 9.5 11.0 2.4 8.6 11.0 1.3 1 0 0 1 1 1 0 Gene product 67 LAT PF15234.6 EMR65185.1 - 2.4 7.8 5.1 4 7.1 5.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells RNA_pol_3_Rpc31 PF11705.8 EMR65185.1 - 2.5 8.3 11.5 4.6 7.4 11.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Lipase_GDSL_2 PF13472.6 EMR65186.1 - 4.6e-10 40.2 0.8 6e-10 39.8 0.8 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR65186.1 - 1.9e-06 28.0 0.1 3.2e-06 27.3 0.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase KR PF08659.10 EMR65187.1 - 2e-52 177.7 0.1 7.5e-52 175.8 0.1 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EMR65187.1 - 3e-21 75.9 0.4 6.9e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.25 EMR65187.1 - 7.8e-13 48.3 0.3 1.7e-12 47.2 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65187.1 - 2.2e-08 34.0 0.1 5e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 EMR65187.1 - 4.4e-06 26.5 0.0 2.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR65187.1 - 0.00025 21.0 0.1 0.00025 21.0 0.1 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EMR65187.1 - 0.0018 18.6 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 EMR65187.1 - 0.0023 17.1 0.5 0.0063 15.7 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein ThiF PF00899.21 EMR65187.1 - 0.043 13.2 1.2 0.091 12.1 1.2 1.4 1 0 0 1 1 1 0 ThiF family NAT PF04768.13 EMR65188.1 - 8.3e-49 165.5 0.7 1.4e-48 164.7 0.2 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EMR65188.1 - 4.1e-32 111.2 0.0 1.3e-31 109.5 0.0 2.0 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EMR65188.1 - 1.8e-30 106.3 0.0 3.3e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family GFO_IDH_MocA PF01408.22 EMR65188.1 - 0.003 18.4 0.0 0.01 16.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 EMR65188.1 - 0.027 14.6 0.0 0.097 12.8 0.0 2.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Asp PF00026.23 EMR65190.1 - 1.6e-67 228.2 2.0 3.6e-67 227.0 2.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR65190.1 - 2.2e-10 41.1 1.0 1.5e-08 35.1 1.0 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMR65190.1 - 0.00092 19.8 0.5 1.6 9.4 0.0 3.5 3 0 0 3 3 3 1 Aspartyl protease Sulfatase PF00884.23 EMR65190.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Sulfatase gag-asp_proteas PF13975.6 EMR65190.1 - 0.036 14.6 0.1 2.7 8.6 0.0 3.2 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DnaJ_C PF01556.18 EMR65191.1 - 1.6e-18 67.3 0.0 8.3e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain Helo_like_N PF17111.5 EMR65191.1 - 0.0001 21.8 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF2408 PF10303.9 EMR65191.1 - 0.045 14.3 0.6 0.25 11.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) TolA_bind_tri PF16331.5 EMR65191.1 - 0.066 13.3 4.4 0.12 12.5 0.6 3.0 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF3073 PF11273.8 EMR65191.1 - 0.11 13.2 0.2 4.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) IL5 PF02025.15 EMR65191.1 - 0.13 12.5 0.0 28 5.1 0.0 3.3 3 0 0 3 3 3 0 Interleukin 5 Syntaxin-6_N PF09177.11 EMR65191.1 - 4.2 8.0 6.4 17 6.1 0.1 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Amidohydro_1 PF01979.20 EMR65192.1 - 2.2e-20 73.3 0.1 3.2e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR65192.1 - 4.9e-09 36.2 1.0 0.00061 19.4 0.1 2.8 1 1 0 2 2 2 2 Amidohydrolase family Hemerythrin PF01814.23 EMR65194.1 - 2.5e-09 37.8 0.5 3.3e-09 37.5 0.5 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Cyclase PF04199.13 EMR65195.1 - 2e-15 57.2 0.0 2.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase EzrA PF06160.12 EMR65196.1 - 0.0012 17.1 11.0 0.0021 16.3 11.0 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 EMR65196.1 - 0.0034 17.7 10.4 12 6.4 1.1 4.8 4 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EMR65196.1 - 0.0046 17.0 13.9 0.0048 16.9 1.6 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EMR65196.1 - 0.01 15.9 6.0 0.95 9.5 1.9 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 EMR65196.1 - 0.013 15.7 3.2 0.013 15.7 3.2 2.9 1 1 2 3 3 3 0 Tropomyosin like AAA_13 PF13166.6 EMR65196.1 - 0.017 13.8 11.1 0.042 12.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain Surfac_D-trimer PF09006.11 EMR65196.1 - 0.047 13.6 5.2 6.8 6.7 0.1 4.5 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation CLZ PF16526.5 EMR65196.1 - 0.051 13.9 19.5 0.26 11.7 5.7 4.2 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 EMR65196.1 - 0.056 13.6 10.6 0.15 12.2 0.3 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EMR65196.1 - 0.11 13.0 7.4 11 6.6 0.5 3.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 EMR65196.1 - 0.22 12.0 14.2 2.6 8.6 0.3 3.3 1 1 2 3 3 3 0 Protein of unknown function DUF16 YkyA PF10368.9 EMR65196.1 - 0.23 11.1 13.9 0.53 9.9 0.7 2.9 1 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Sipho_Gp157 PF05565.11 EMR65196.1 - 0.27 11.3 21.3 2.1 8.3 8.7 3.2 2 1 1 3 3 3 0 Siphovirus Gp157 Laminin_II PF06009.12 EMR65196.1 - 0.37 10.8 9.9 0.5 10.4 0.9 2.8 1 1 2 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 EMR65196.1 - 0.64 9.5 12.9 7.2 6.1 13.1 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit Lipoprotein_2 PF00921.17 EMR65196.1 - 0.68 9.4 6.2 1.9 8.0 0.0 2.5 2 1 0 2 2 2 0 Borrelia lipoprotein DUF4988 PF16378.5 EMR65196.1 - 0.68 9.6 3.5 15 5.2 0.0 3.6 2 2 2 4 4 4 0 Domain of unknown function DUF2130 PF09903.9 EMR65196.1 - 0.69 9.1 12.5 0.079 12.2 4.6 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2130) Lectin_N PF03954.14 EMR65196.1 - 0.99 9.2 7.3 0.87 9.3 0.1 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Sec34 PF04136.15 EMR65196.1 - 1.1 9.1 10.6 11 5.9 0.1 3.1 2 1 1 3 3 3 0 Sec34-like family Not3 PF04065.15 EMR65196.1 - 1.9 7.9 16.6 0.71 9.3 5.7 2.8 1 1 2 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component TPX2 PF06886.11 EMR65196.1 - 2.1 8.6 17.1 0.06 13.6 1.8 3.5 2 1 1 3 3 3 0 Targeting protein for Xklp2 (TPX2) Phasin PF05597.11 EMR65196.1 - 2.5 8.1 16.0 5.6 7.0 3.2 3.4 1 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Noelin-1 PF12308.8 EMR65196.1 - 3 7.9 6.5 11 6.0 0.2 3.1 2 1 2 4 4 4 0 Neurogenesis glycoprotein ATG16 PF08614.11 EMR65196.1 - 3.1 8.0 18.0 0.75 10.0 10.9 2.8 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FapA PF03961.13 EMR65196.1 - 4.2 5.9 14.2 0.52 8.9 5.7 2.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3987 PF13148.6 EMR65196.1 - 4.4 6.2 10.2 0.96 8.4 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Allexi_40kDa PF05549.11 EMR65196.1 - 5 6.6 10.7 15 5.0 1.3 3.1 1 1 2 3 3 3 0 Allexivirus 40kDa protein DUF4795 PF16043.5 EMR65196.1 - 5.8 6.5 19.3 4.6 6.8 1.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Exonuc_VII_S PF02609.16 EMR65196.1 - 9.7 6.3 10.8 16 5.7 0.3 4.2 4 1 1 5 5 4 0 Exonuclease VII small subunit 2OG-FeII_Oxy_3 PF13640.6 EMR65197.1 - 3.4e-11 43.9 0.0 5.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YL1 PF05764.13 EMR65198.1 - 5.3e-72 242.9 29.4 5.3e-72 242.9 29.4 2.8 3 0 0 3 3 3 1 YL1 nuclear protein DUF572 PF04502.13 EMR65198.1 - 0.81 9.2 33.2 0.16 11.6 13.7 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF572) MFS_1 PF07690.16 EMR65199.1 - 5.1e-08 32.2 9.3 5.1e-08 32.2 9.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65199.1 - 0.00055 18.9 1.6 0.00064 18.7 1.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PRIMA1 PF16101.5 EMR65199.1 - 0.45 10.6 7.0 0.72 9.9 7.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 EMR65199.1 - 0.77 9.8 4.5 0.9 9.6 4.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EMR65199.1 - 1.1 8.7 7.0 1.6 8.2 7.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.16 EMR65200.1 - 1.1e-19 70.5 34.5 7.5e-15 54.7 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65200.1 - 8.9e-10 38.0 16.5 1.3e-09 37.5 16.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Ferric_reduct PF01794.19 EMR65201.1 - 1.4e-13 51.0 6.6 1.4e-13 51.0 6.6 1.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMR65201.1 - 5.7e-10 39.3 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMR65201.1 - 0.0012 19.0 0.0 0.0035 17.5 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Gln-synt_C PF00120.24 EMR65202.1 - 7.1e-52 176.5 0.0 1.7e-51 175.3 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Aldedh PF00171.22 EMR65203.1 - 1.5e-134 449.0 0.1 1.8e-134 448.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DnaJ-X PF14308.6 EMR65204.1 - 1.3e-75 253.5 4.8 1.3e-75 253.5 4.8 2.4 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 EMR65204.1 - 2.6e-25 88.3 1.3 6e-25 87.1 1.3 1.7 1 0 0 1 1 1 1 DnaJ domain Activator-TraM PF11657.8 EMR65204.1 - 3.7 7.4 7.3 0.22 11.3 1.6 1.8 2 0 0 2 2 2 0 Transcriptional activator TraM KdpC PF02669.15 EMR65205.1 - 0.033 14.0 0.9 0.049 13.5 0.9 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain KxDL PF10241.9 EMR65205.1 - 0.34 11.2 7.8 2.7 8.4 0.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF2570 PF10828.8 EMR65205.1 - 6.3 6.7 9.7 0.22 11.4 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) FUSC PF04632.12 EMR65205.1 - 9.9 4.6 5.9 13 4.2 5.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADH_N PF08240.12 EMR65206.1 - 5.3e-25 87.4 1.2 1e-24 86.5 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 EMR65206.1 - 2.6e-09 36.9 2.2 2e-08 34.0 0.1 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 EMR65206.1 - 8.9e-09 35.4 0.2 9.4e-05 22.4 0.0 2.8 3 0 0 3 3 3 2 Zinc-binding dehydrogenase Fungal_trans PF04082.18 EMR65207.1 - 6.2e-11 41.8 0.5 6.2e-11 41.8 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Spt20 PF12090.8 EMR65207.1 - 0.0022 17.6 14.6 0.0034 17.0 14.6 1.1 1 0 0 1 1 1 1 Spt20 family SUIM_assoc PF16619.5 EMR65207.1 - 0.003 17.6 6.1 0.003 17.6 6.1 1.8 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 EMR65207.1 - 0.015 15.3 6.6 0.021 14.8 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 EMR65207.1 - 0.031 13.2 9.2 0.049 12.5 9.2 1.2 1 0 0 1 1 1 0 Androgen receptor DUF1180 PF06679.12 EMR65207.1 - 0.9 9.9 5.7 1.4 9.3 4.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TERB2 PF15101.6 EMR65207.1 - 0.9 9.5 7.3 25 4.8 0.0 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Med3 PF11593.8 EMR65207.1 - 1.4 8.0 14.9 2.4 7.3 14.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4770 PF15994.5 EMR65207.1 - 2.1 8.6 6.2 1.7 8.8 4.1 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) DUF4834 PF16118.5 EMR65207.1 - 2.4 9.2 5.5 4.3 8.4 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 EMR65207.1 - 4.4 6.1 17.8 6.5 5.6 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 EMR65207.1 - 9.3 5.2 6.2 14 4.6 6.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF1996 PF09362.10 EMR65208.1 - 6.6e-65 219.4 0.0 9.3e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EMR65208.1 - 1.2e-15 57.5 5.1 2.4e-15 56.5 5.1 1.5 1 0 0 1 1 1 1 WSC domain Hydrolase_6 PF13344.6 EMR65210.1 - 4.1e-23 81.4 0.0 7.9e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR65210.1 - 2.5e-14 53.1 0.1 2.9e-13 49.7 0.0 2.6 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 EMR65210.1 - 0.009 16.3 0.0 0.4 10.9 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR65210.1 - 0.079 13.0 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase FSH1 PF03959.13 EMR65211.1 - 3.2e-28 98.9 0.0 5.9e-27 94.7 0.0 2.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AAA PF00004.29 EMR65212.1 - 1.4e-34 119.4 0.0 1.3e-33 116.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR65212.1 - 1.1e-05 25.9 0.3 0.0049 17.3 0.0 3.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EMR65212.1 - 5.6e-05 23.3 0.0 0.00024 21.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMR65212.1 - 6.8e-05 22.9 0.0 0.00025 21.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMR65212.1 - 7e-05 23.1 0.1 0.016 15.4 0.0 2.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EMR65212.1 - 0.00015 21.6 0.0 0.00044 20.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EMR65212.1 - 0.00021 21.0 0.0 0.00065 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EMR65212.1 - 0.00023 21.0 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EMR65212.1 - 0.0023 17.2 0.1 0.016 14.5 0.1 2.1 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_18 PF13238.6 EMR65212.1 - 0.0029 18.1 0.0 0.032 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 EMR65212.1 - 0.0044 17.1 0.0 0.035 14.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 EMR65212.1 - 0.0072 16.0 0.1 0.034 13.8 0.0 2.2 2 1 0 2 2 2 1 Sigma-54 interaction domain IPT PF01745.16 EMR65212.1 - 0.0087 15.5 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_24 PF13479.6 EMR65212.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR65212.1 - 0.014 15.7 0.0 0.075 13.4 0.0 2.3 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EMR65212.1 - 0.017 15.1 0.0 4.4 7.1 0.0 3.2 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EMR65212.1 - 0.018 15.1 0.0 0.07 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EMR65212.1 - 0.031 14.1 0.2 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EMR65212.1 - 0.037 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 EMR65212.1 - 0.042 14.0 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_6 PF12774.7 EMR65212.1 - 0.046 12.7 0.1 0.078 11.9 0.1 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Parvo_NS1 PF01057.17 EMR65212.1 - 0.048 12.8 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EMR65212.1 - 0.061 13.8 0.3 0.56 10.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 EMR65212.1 - 0.064 13.5 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 EMR65212.1 - 0.1 12.9 0.1 0.1 12.9 0.1 2.2 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain Mg_chelatase PF01078.21 EMR65212.1 - 0.12 11.7 0.1 0.42 10.0 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 EMR65212.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_3 PF07726.11 EMR65212.1 - 0.15 11.9 0.0 0.71 9.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SHMT PF00464.19 EMR65213.1 - 3.2e-158 526.5 0.0 3.9e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase V-ATPase_G PF03179.15 EMR65214.1 - 7.4e-27 93.9 13.8 8.5e-27 93.8 13.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit SAPS PF04499.15 EMR65214.1 - 0.45 9.2 6.4 0.52 9.0 6.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRF PF01765.19 EMR65214.1 - 1.3 9.0 10.9 1.7 8.6 10.9 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF2175 PF09943.9 EMR65214.1 - 2 8.8 7.4 1.5 9.1 2.8 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) HA2 PF04408.23 EMR65215.1 - 3.5e-15 56.2 0.0 3.5e-15 56.2 0.0 3.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMR65215.1 - 1.2e-14 54.6 0.1 3.5e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMR65215.1 - 3e-07 30.7 0.0 6.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EMR65215.1 - 1.1e-05 25.3 0.1 2.3e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase His_Phos_1 PF00300.22 EMR65216.1 - 2.7e-16 59.9 0.0 3.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FAD_binding_4 PF01565.23 EMR65217.1 - 2.7e-20 72.6 1.7 4.1e-20 71.9 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR65217.1 - 7.2e-09 35.6 0.0 2.6e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Abhydrolase_1 PF00561.20 EMR65218.1 - 2.9e-20 73.0 0.0 2e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EMR65218.1 - 1.6e-17 63.5 0.1 4.7e-17 62.0 0.1 1.8 1 1 0 1 1 1 1 TAP-like protein Epimerase PF01370.21 EMR65218.1 - 1e-12 48.0 0.1 3.7e-12 46.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR65218.1 - 1.3e-09 38.2 0.6 2.3e-09 37.4 0.6 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EMR65218.1 - 2.5e-07 30.0 0.0 1.4e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EMR65218.1 - 1.4e-06 28.1 0.5 2.7e-06 27.1 0.5 1.5 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EMR65218.1 - 2.6e-06 27.1 0.1 5.5e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 EMR65218.1 - 0.00027 20.3 0.2 0.0005 19.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EMR65218.1 - 0.00036 20.8 0.3 0.00083 19.6 0.3 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 EMR65218.1 - 0.00052 20.2 0.1 0.00096 19.3 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EMR65218.1 - 0.0031 17.6 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EMR65218.1 - 0.006 16.8 0.2 0.013 15.8 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EMR65218.1 - 0.006 15.7 0.0 0.057 12.5 0.2 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain ApbA PF02558.16 EMR65218.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EMR65218.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EMR65218.1 - 0.094 13.4 1.5 0.11 13.1 0.3 1.8 2 0 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EMR65218.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMR65218.1 - 0.11 12.4 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMR65218.1 - 0.19 11.3 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PET117 PF15786.5 EMR65219.1 - 1.6e-20 73.1 2.0 2e-20 72.8 2.0 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Pox_D5 PF03288.16 EMR65219.1 - 0.0056 17.1 0.1 0.0069 16.9 0.1 1.1 1 0 0 1 1 1 1 Poxvirus D5 protein-like Glyco_hydro_2_N PF02837.18 EMR65220.1 - 9.3e-15 54.9 0.3 3.2e-14 53.2 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EMR65220.1 - 2e-10 41.3 0.1 2.1e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EMR65220.1 - 3.3e-09 36.3 0.0 1.7e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Adeno_GP19K PF04881.13 EMR65220.1 - 0.065 13.2 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Adenovirus GP19K zf-MYND PF01753.18 EMR65221.1 - 9.3e-10 38.4 14.8 1.8e-09 37.5 14.8 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EMR65221.1 - 0.25 11.7 13.2 0.44 10.9 13.2 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Cyt-b5 PF00173.28 EMR65222.1 - 3.1e-15 56.1 0.0 5.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EMR65222.1 - 0.08 12.8 0.6 0.11 12.3 0.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase RNA_pol_Rpb2_6 PF00562.28 EMR65223.1 - 2.2e-124 415.5 0.0 3.7e-124 414.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EMR65223.1 - 2.9e-53 180.4 0.0 7.6e-53 179.1 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EMR65223.1 - 2.3e-47 161.1 0.0 4.6e-47 160.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EMR65223.1 - 5.8e-33 113.2 0.1 1.4e-32 112.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EMR65223.1 - 1.7e-25 89.0 0.1 5.8e-25 87.3 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EMR65223.1 - 8.3e-24 83.9 1.6 2.4e-23 82.4 1.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 EMR65223.1 - 1.6e-23 82.7 0.1 4.4e-23 81.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 MRNIP PF15749.5 EMR65223.1 - 0.18 12.6 0.1 0.53 11.0 0.1 1.8 1 0 0 1 1 1 0 MRN-interacting protein KR PF08659.10 EMR65224.1 - 2.5e-63 213.3 2.5 1.8e-62 210.4 0.8 3.3 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EMR65224.1 - 2.3e-55 188.0 0.0 4.1e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EMR65224.1 - 5.9e-50 170.2 0.1 3.1e-49 167.8 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EMR65224.1 - 2.9e-48 165.0 1.2 5.3e-48 164.2 1.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR65224.1 - 6.2e-35 119.8 0.3 1.8e-34 118.3 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EMR65224.1 - 7e-18 65.2 0.0 2.6e-16 60.1 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 EMR65224.1 - 2.9e-15 56.4 2.6 9.5e-15 54.7 0.0 3.3 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR65224.1 - 4.9e-15 56.8 0.0 4.2e-13 50.5 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR65224.1 - 6.7e-14 51.8 0.7 8.9e-13 48.1 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EMR65224.1 - 1.1e-13 51.6 0.1 1.2e-11 45.1 0.1 2.7 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EMR65224.1 - 1.4e-12 48.1 0.0 2.7e-11 44.0 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR65224.1 - 1.9e-09 38.0 2.9 6.2e-09 36.4 0.0 3.6 6 0 0 6 6 2 1 Methyltransferase domain ADH_N PF08240.12 EMR65224.1 - 3.2e-09 36.6 0.2 8.9e-09 35.2 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.6 EMR65224.1 - 3.2e-08 33.6 0.0 7.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EMR65224.1 - 1.4e-05 24.8 1.0 3.1e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 EMR65224.1 - 0.00014 21.7 0.0 0.00054 19.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR65224.1 - 0.00059 20.1 0.0 0.0018 18.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EMR65224.1 - 0.0034 16.8 0.0 0.0086 15.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Phage_Coat_B PF05356.11 EMR65224.1 - 0.046 13.6 1.3 0.11 12.4 0.2 2.3 2 0 0 2 2 1 0 Phage Coat protein B DUF915 PF06028.11 EMR65224.1 - 0.073 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PALP PF00291.25 EMR65224.1 - 0.11 11.9 5.1 0.57 9.5 0.1 3.1 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme Abhydrolase_6 PF12697.7 EMR65224.1 - 0.25 11.9 1.4 6.2 7.4 0.1 2.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family adh_short_C2 PF13561.6 EMR65225.1 - 7.1e-51 173.0 0.0 1e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR65225.1 - 3.9e-39 134.1 0.0 6e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR65225.1 - 3.8e-08 33.5 0.2 5.8e-08 32.9 0.2 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EMR65225.1 - 0.089 12.1 0.0 0.53 9.6 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MIOX PF05153.15 EMR65226.1 - 6e-125 415.8 1.0 8.9e-125 415.3 1.0 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase AAA PF00004.29 EMR65226.1 - 6.2e-08 33.1 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UBD PF16455.5 EMR65226.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-binding domain MR_MLE_C PF13378.6 EMR65227.1 - 3.9e-41 141.0 0.0 5.2e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMR65227.1 - 6.9e-10 39.2 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Gcn1_N PF12074.8 EMR65229.1 - 9e-38 130.5 7.9 7.4e-23 81.4 0.1 5.3 5 1 1 6 6 6 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EMR65229.1 - 2.2e-30 102.1 45.7 0.02 15.1 0.1 21.7 25 0 0 25 25 23 8 HEAT repeat HEAT_EZ PF13513.6 EMR65229.1 - 4.3e-29 100.6 54.2 7.5e-07 29.5 0.1 19.9 19 4 6 25 25 19 8 HEAT-like repeat HEAT_2 PF13646.6 EMR65229.1 - 4.2e-26 91.2 44.6 1.7e-05 25.1 0.1 15.6 11 4 8 19 19 19 10 HEAT repeats Vac14_Fab1_bd PF12755.7 EMR65229.1 - 5.9e-16 58.9 0.0 0.81 10.3 0.0 9.6 7 2 1 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EMR65229.1 - 4.7e-15 56.0 4.8 0.38 10.8 0.1 10.5 4 2 6 12 12 12 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EMR65229.1 - 1e-11 44.9 0.0 0.21 11.1 0.0 6.7 4 1 2 6 6 6 3 CLASP N terminal ParcG PF10274.9 EMR65229.1 - 1.1e-11 45.2 2.0 0.001 19.2 0.0 5.5 6 0 0 6 6 4 3 Parkin co-regulated protein Adaptin_N PF01602.20 EMR65229.1 - 2.1e-10 39.8 0.7 0.0023 16.5 0.0 7.1 6 3 2 8 8 8 3 Adaptin N terminal region MMS19_C PF12460.8 EMR65229.1 - 3.5e-07 29.7 22.9 4.6e-05 22.7 0.1 7.8 6 2 1 8 8 8 2 RNAPII transcription regulator C-terminal TIP120 PF08623.10 EMR65229.1 - 9.3e-07 28.8 1.8 0.012 15.4 0.0 6.3 6 1 1 7 7 6 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 EMR65229.1 - 7.8e-06 25.9 0.0 1.7 8.6 0.0 6.4 6 2 0 6 6 6 1 Domain of unknown function (DUF3385) DUF937 PF06078.11 EMR65229.1 - 0.00025 21.6 5.4 11 6.6 0.0 6.8 5 2 0 6 6 6 0 Bacterial protein of unknown function (DUF937) Tti2 PF10521.9 EMR65229.1 - 0.0057 16.2 10.8 0.43 10.1 0.0 7.2 7 3 3 10 10 10 1 Tti2 family NUC173 PF08161.12 EMR65229.1 - 0.0073 16.0 5.7 1 9.0 0.1 5.9 6 2 2 8 8 8 1 NUC173 domain Pes-10 PF07149.11 EMR65229.1 - 0.0087 15.2 0.1 0.019 14.0 0.1 1.5 1 0 0 1 1 1 1 Pes-10 FANCI_S2 PF14676.6 EMR65229.1 - 0.016 15.5 0.1 1.2 9.4 0.1 4.2 6 0 0 6 6 4 0 FANCI solenoid 2 TFCD_C PF12612.8 EMR65229.1 - 0.055 13.3 2.8 0.77 9.6 0.0 4.4 5 1 0 5 5 5 0 Tubulin folding cofactor D C terminal DRIM PF07539.12 EMR65229.1 - 0.12 10.6 16.6 0.6 8.4 0.3 5.1 5 2 1 6 6 6 0 Down-regulated in metastasis U3snoRNP10 PF12397.8 EMR65229.1 - 0.14 12.5 18.5 12 6.3 0.3 7.9 8 0 0 8 8 7 0 U3 small nucleolar RNA-associated protein 10 RIX1 PF08167.12 EMR65229.1 - 0.47 10.2 9.0 0.11 12.2 0.3 4.4 4 1 0 4 4 3 0 rRNA processing/ribosome biogenesis ADSL_C PF10397.9 EMR65229.1 - 0.97 10.0 4.5 11 6.7 0.0 4.5 4 0 0 4 4 3 0 Adenylosuccinate lyase C-terminus Ipi1_N PF12333.8 EMR65229.1 - 5.7 7.6 8.9 0.32 11.6 0.1 3.8 4 0 0 4 4 2 0 Rix1 complex component involved in 60S ribosome maturation RRM_1 PF00076.22 EMR65230.1 - 5.9e-41 138.1 0.1 2e-12 46.7 0.2 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMR65230.1 - 7.9e-33 112.2 0.0 1.3e-28 98.6 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EMR65230.1 - 1.5e-06 27.9 0.0 0.13 11.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMR65230.1 - 7e-05 22.7 0.0 0.51 10.4 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 EMR65230.1 - 0.00048 20.0 0.0 0.024 14.6 0.0 3.1 3 0 0 3 3 3 1 RL domain Nup35_RRM PF05172.13 EMR65230.1 - 0.017 15.1 0.1 0.14 12.1 0.0 2.5 3 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.11 EMR65230.1 - 0.024 14.1 0.2 0.052 13.1 0.2 1.6 1 0 0 1 1 1 0 Lsm interaction motif DUF3306 PF11748.8 EMR65230.1 - 0.51 11.2 5.3 2.7 8.9 5.3 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Ribosomal_L19e PF01280.20 EMR65231.1 - 1.5e-61 206.7 6.5 1.5e-61 206.7 6.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e TRAP-gamma PF07074.12 EMR65231.1 - 5.6 6.5 5.5 8.2 5.9 5.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) CTNNBL PF08216.11 EMR65232.1 - 5.4e-35 119.7 0.2 3.2e-34 117.2 0.1 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear PDCD2_C PF04194.13 EMR65232.1 - 0.069 13.2 0.5 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Glyco_transf_22 PF03901.17 EMR65234.1 - 2.5e-26 92.9 8.3 3e-26 92.6 8.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Phospholip_A2_3 PF09056.11 EMR65235.1 - 0.043 14.4 0.0 0.082 13.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 Mito_carr PF00153.27 EMR65236.1 - 2.4e-48 162.0 5.2 2.9e-18 65.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF218 PF02698.17 EMR65237.1 - 5.4e-22 78.2 0.0 7.1e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain AA_permease_2 PF13520.6 EMR65238.1 - 3.2e-24 85.5 12.5 3.2e-24 85.5 12.5 2.7 1 1 2 3 3 3 2 Amino acid permease AA_permease PF00324.21 EMR65238.1 - 5.7e-10 38.4 28.9 1.3e-08 33.9 15.1 2.4 2 1 0 2 2 2 2 Amino acid permease DUF3611 PF12263.8 EMR65238.1 - 0.037 13.9 1.1 0.037 13.9 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) Crystallin PF00525.18 EMR65239.1 - 0.065 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal Ubie_methyltran PF01209.18 EMR65240.1 - 1.8e-13 50.4 0.0 4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EMR65240.1 - 4.2e-12 46.6 0.0 8.9e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR65240.1 - 8e-12 45.7 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR65240.1 - 6.2e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR65240.1 - 1.1e-07 32.5 0.1 7.3e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR65240.1 - 2.4e-07 30.6 0.0 7.1e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EMR65240.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_1 PF00076.22 EMR65241.1 - 1.5e-08 34.3 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMR65241.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EMR65241.1 - 0.00029 20.7 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EMR65241.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif F-box-like PF12937.7 EMR65243.1 - 0.00019 21.3 0.0 0.0014 18.5 0.0 2.4 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EMR65243.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain CC2D2AN-C2 PF15625.6 EMR65243.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Phasin PF05597.11 EMR65243.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Sulfotransfer_4 PF17784.1 EMR65244.1 - 1.4e-45 155.8 0.0 1.6e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR65244.1 - 0.16 12.3 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family RAC_head PF16717.5 EMR65246.1 - 1.4e-30 106.1 2.8 1.4e-30 106.1 2.8 4.1 3 1 1 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 EMR65246.1 - 2.3e-19 69.3 0.8 2.3e-19 69.3 0.8 2.7 2 0 0 2 2 2 1 DnaJ domain V_ATPase_I PF01496.19 EMR65246.1 - 0.21 9.5 8.5 0.39 8.6 8.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M14 PF00246.24 EMR65247.1 - 6.1e-69 233.0 0.0 7e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Complex1_LYR PF05347.15 EMR65248.1 - 3.2e-06 27.1 0.0 5.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EMR65248.1 - 0.00023 21.8 0.0 0.00027 21.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Cys_Knot_tox PF17486.2 EMR65248.1 - 0.077 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Cystine knot toxins GLEYA PF10528.9 EMR65249.1 - 4.8e-21 75.0 2.9 4.8e-21 75.0 2.9 2.9 3 2 0 3 3 3 1 GLEYA domain MCM PF00493.23 EMR65251.1 - 1.3e-100 335.1 0.0 2.1e-100 334.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMR65251.1 - 8.9e-39 132.2 0.1 1.7e-38 131.3 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EMR65251.1 - 1.3e-33 116.5 37.2 1.3e-33 116.5 37.2 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EMR65251.1 - 2.5e-25 88.7 0.5 7.2e-25 87.2 0.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMR65251.1 - 4.9e-15 56.0 0.1 1.3e-14 54.6 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMR65251.1 - 2.6e-07 30.3 0.0 7.2e-06 25.5 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMR65251.1 - 1.1e-05 25.5 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EMR65251.1 - 0.0035 17.2 0.1 0.039 13.8 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMR65251.1 - 0.0039 16.9 0.2 0.017 14.8 0.2 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain MFS_1 PF07690.16 EMR65252.1 - 2.2e-14 53.2 22.6 2.2e-14 53.2 22.6 2.5 1 1 0 2 2 2 1 Major Facilitator Superfamily 4HBT PF03061.22 EMR65253.1 - 1.7e-08 34.7 1.4 2.4e-08 34.2 1.0 1.5 1 1 1 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 EMR65253.1 - 0.00085 19.6 0.4 0.0011 19.3 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 EMR65253.1 - 0.033 14.7 0.0 0.034 14.6 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily IDO PF01231.18 EMR65254.1 - 1.8e-160 534.5 0.0 2.1e-160 534.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Peptidase_S8 PF00082.22 EMR65255.1 - 4.5e-28 98.4 6.7 5.6e-28 98.0 6.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR65255.1 - 1.5e-13 51.2 0.0 3.1e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 ECR1_N PF14382.6 EMR65255.1 - 0.23 11.3 1.4 0.97 9.3 0.2 2.6 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region adh_short_C2 PF13561.6 EMR65256.1 - 1.4e-60 204.8 0.3 1.6e-60 204.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR65256.1 - 8.6e-51 172.2 1.2 9.9e-51 172.0 1.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR65256.1 - 4.9e-15 55.9 0.5 7.2e-15 55.4 0.5 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR65256.1 - 0.015 14.4 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EPO_TPO PF00758.18 EMR65256.1 - 0.027 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin 3HCDH_N PF02737.18 EMR65256.1 - 0.078 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DLH PF01738.18 EMR65257.1 - 1.5e-16 60.7 0.0 3.8e-16 59.3 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Rep_N PF08724.10 EMR65259.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Rep protein catalytic domain like SPDY PF03771.16 EMR65259.1 - 0.054 13.4 0.3 0.12 12.3 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF317) DUF3716 PF12511.8 EMR65260.1 - 5.9e-15 55.1 2.6 8.9e-15 54.5 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cytochrom_B558a PF05038.13 EMR65260.1 - 0.028 14.0 0.5 0.054 13.1 0.5 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Zn_clus PF00172.18 EMR65260.1 - 6.1 7.1 7.8 20 5.4 1.8 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylsulfotran_2 PF14269.6 EMR65261.1 - 3.9e-54 184.1 1.4 5.9e-54 183.5 0.8 1.6 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMR65261.1 - 5.8e-22 78.1 0.9 1.5e-21 76.8 0.9 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) zf-UBR PF02207.20 EMR65262.1 - 2.7e-13 49.9 8.5 2.7e-13 49.9 8.5 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) BUD22 PF09073.10 EMR65262.1 - 1.6 8.0 16.0 0.015 14.6 8.0 1.6 2 0 0 2 2 2 0 BUD22 Rep_4 PF05797.11 EMR65262.1 - 6.5 5.8 4.7 5 6.1 0.7 2.1 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) MFS_1 PF07690.16 EMR65263.1 - 3.6e-19 68.9 25.0 3.6e-12 45.9 19.2 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65263.1 - 0.019 13.9 20.8 0.23 10.3 1.5 2.8 2 1 1 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 EMR65264.1 - 4e-28 98.4 40.6 5.2e-28 98.0 40.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR65264.1 - 0.007 15.7 20.2 0.014 14.7 20.2 1.4 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Vps23_core PF09454.10 EMR65265.1 - 7.3e-20 70.7 0.0 1.2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain Sugar_tr PF00083.24 EMR65266.1 - 1.1e-96 324.5 10.4 1.3e-96 324.2 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR65266.1 - 1.2e-34 119.8 36.2 5.1e-27 94.7 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR65266.1 - 3.7e-07 29.1 16.3 7.5e-06 24.8 2.0 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 EMR65266.1 - 0.0025 16.2 11.2 0.015 13.6 5.5 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EMR65266.1 - 0.003 16.5 4.3 0.01 14.7 0.4 2.4 2 1 0 2 2 2 1 MFS_1 like family Fig1 PF12351.8 EMR65266.1 - 0.064 13.2 3.7 0.12 12.3 0.9 2.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 TRI12 PF06609.13 EMR65266.1 - 0.065 11.6 8.9 0.01 14.3 1.5 2.5 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EMR65266.1 - 0.084 11.3 5.5 0.59 8.5 0.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2644 PF10841.8 EMR65266.1 - 4.5 7.6 6.2 0.69 10.2 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) DUF2530 PF10745.9 EMR65266.1 - 4.7 7.5 7.9 17 5.7 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Hce2 PF14856.6 EMR65267.1 - 1.6e-07 31.6 0.3 2.1e-07 31.2 0.3 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF3509 PF12021.8 EMR65268.1 - 0.095 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) UBM PF14377.6 EMR65268.1 - 0.19 11.2 0.4 0.43 10.1 0.4 1.6 1 0 0 1 1 1 0 Ubiquitin binding region DDHD PF02862.17 EMR65269.1 - 0.36 11.0 7.5 0.61 10.2 1.8 2.2 2 0 0 2 2 2 0 DDHD domain TFIIA PF03153.13 EMR65269.1 - 0.38 10.7 23.3 0.94 9.4 13.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WDCP PF15390.6 EMR65269.1 - 5.3 5.3 9.0 8.3 4.7 9.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Vfa1 PF08432.10 EMR65269.1 - 7.8 6.8 29.4 1.1 9.5 1.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FTA4 PF13093.6 EMR65270.1 - 1.2e-64 218.0 0.0 1.5e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 KfrA_N PF11740.8 EMR65270.1 - 0.75 10.5 8.9 6.2 7.5 1.2 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term p450 PF00067.22 EMR65271.1 - 8.8e-05 21.4 0.0 0.0074 15.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF2542 PF10808.8 EMR65272.1 - 0.062 13.8 1.6 6.4 7.3 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2542) Beta-lactamase PF00144.24 EMR65273.1 - 1e-49 169.6 0.0 1.5e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EMR65273.1 - 5.1e-07 30.1 0.1 1.2e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase2 PF13354.6 EMR65273.1 - 0.00023 20.8 0.0 0.0016 18.1 0.0 2.3 3 0 0 3 3 3 1 Beta-lactamase enzyme family Pkip-1 PF06878.11 EMR65273.1 - 0.23 11.5 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 Pkip-1 protein CoA_transf_3 PF02515.17 EMR65274.1 - 1.3e-37 129.8 0.0 2.2e-36 125.7 0.0 2.4 2 0 0 2 2 2 1 CoA-transferase family III bZIP_1 PF00170.21 EMR65274.1 - 0.00023 21.2 1.6 0.0007 19.6 1.6 1.8 1 0 0 1 1 1 1 bZIP transcription factor UBA_3 PF09288.10 EMR65275.1 - 0.021 14.6 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Retrotrans_gag PF03732.17 EMR65275.1 - 0.095 13.0 1.9 0.14 12.5 0.3 2.1 2 1 1 3 3 3 0 Retrotransposon gag protein JHD PF17811.1 EMR65275.1 - 0.17 12.4 1.3 0.52 10.9 0.1 2.2 2 0 0 2 2 2 0 Jumonji helical domain Glyco_hydro_3_C PF01915.22 EMR65276.1 - 1.9e-63 214.1 0.0 3.4e-63 213.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR65276.1 - 7.5e-43 147.1 0.0 1.3e-42 146.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR65276.1 - 4.7e-25 87.5 0.2 1.1e-24 86.3 0.2 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EMR65276.1 - 1.8e-13 50.5 0.0 3.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Peptidase_C2 PF00648.21 EMR65277.1 - 1.2e-61 208.4 2.2 4e-42 144.3 0.4 2.5 3 0 0 3 3 3 2 Calpain family cysteine protease AvrLm4-7 PF18661.1 EMR65277.1 - 0.15 13.1 0.1 0.42 11.7 0.1 1.7 1 0 0 1 1 1 0 Avirulence Effector AvrLm4-7 Phage_HK97_TLTM PF06120.11 EMR65278.1 - 0.03 13.5 0.1 0.037 13.2 0.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Yip1 PF04893.17 EMR65278.1 - 0.069 12.9 0.0 0.098 12.4 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain DUF4307 PF14155.6 EMR65278.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Methyltransf_11 PF08241.12 EMR65279.1 - 1.4e-22 80.1 0.0 2.4e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR65279.1 - 1.5e-22 80.1 0.0 2.5e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR65279.1 - 4.4e-20 72.0 0.0 5.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR65279.1 - 3.8e-14 53.2 0.0 6.6e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR65279.1 - 4.7e-14 52.5 0.0 7.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR65279.1 - 2.5e-12 46.7 0.0 3.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMR65279.1 - 1.4e-07 31.2 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EMR65279.1 - 2.2e-05 24.3 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 EMR65279.1 - 0.00014 20.6 0.0 0.00022 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 EMR65279.1 - 0.00014 21.4 0.0 0.00094 18.7 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 EMR65279.1 - 0.00014 21.2 0.0 0.00028 20.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EMR65279.1 - 0.00018 21.5 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EMR65279.1 - 0.0004 20.3 0.0 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EMR65279.1 - 0.0016 17.6 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 EMR65279.1 - 0.0021 17.7 0.0 0.0052 16.4 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltr_RsmB-F PF01189.17 EMR65279.1 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EMR65279.1 - 0.004 17.3 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 EMR65279.1 - 0.011 15.6 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase NOG1_N PF17835.1 EMR65279.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 NOG1 N-terminal helical domain PrmA PF06325.13 EMR65279.1 - 0.021 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 EMR65279.1 - 0.021 14.3 0.0 3.5 7.1 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain NodS PF05401.11 EMR65279.1 - 0.03 13.9 0.0 0.049 13.3 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.17 EMR65279.1 - 0.066 12.4 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 EMR65279.1 - 0.081 11.8 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Sulfotransfer_4 PF17784.1 EMR65281.1 - 3.9e-72 242.6 0.0 4.9e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR65281.1 - 2.2e-06 28.2 0.1 0.0078 16.6 0.1 2.3 1 1 1 2 2 2 2 Sulfotransferase family CytB6-F_Fe-S PF08802.10 EMR65281.1 - 0.0047 16.9 0.2 0.012 15.6 0.2 1.7 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit ETRAMP PF09716.10 EMR65282.1 - 0.38 10.8 2.9 1.2 9.2 0.3 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) V-ATPase_G PF03179.15 EMR65282.1 - 8.4 7.0 12.1 19 5.9 1.8 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit PRP1_N PF06424.12 EMR65283.1 - 4.8e-52 176.3 8.3 1.4e-51 174.8 8.3 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EMR65283.1 - 3.8e-33 111.3 49.0 3.3e-06 27.5 0.4 14.1 3 2 12 15 15 15 12 Tetratricopeptide repeat TPR_19 PF14559.6 EMR65283.1 - 1.2e-29 102.6 21.4 1.1e-09 38.6 1.0 9.8 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EMR65283.1 - 6.3e-15 55.5 34.5 7e-06 26.6 0.1 8.1 5 2 2 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EMR65283.1 - 1.3e-13 50.0 19.7 0.075 13.2 0.0 10.7 11 1 1 12 12 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 EMR65283.1 - 6.5e-12 44.7 1.9 0.013 15.7 0.0 7.8 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMR65283.1 - 7.4e-12 44.8 5.8 0.31 11.5 0.0 9.4 9 1 1 10 10 10 2 Tetratricopeptide repeat NARP1 PF12569.8 EMR65283.1 - 1.5e-07 30.7 4.9 0.091 11.7 0.0 5.6 4 1 2 6 6 6 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 EMR65283.1 - 2.6e-07 30.2 32.0 0.0012 18.2 5.9 7.0 2 2 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMR65283.1 - 6e-07 29.5 15.4 9.1e-05 22.5 0.2 6.8 4 2 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR65283.1 - 3.7e-06 26.5 5.6 0.13 12.1 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR65283.1 - 5.5e-06 26.5 1.5 0.39 11.0 0.0 5.5 4 1 2 7 7 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EMR65283.1 - 0.00015 22.2 17.7 49 4.9 0.1 9.5 10 0 0 10 10 9 0 Tetratricopeptide repeat Suf PF05843.14 EMR65283.1 - 0.00035 20.6 1.5 4.2 7.3 0.1 4.8 4 1 2 6 6 6 1 Suppressor of forked protein (Suf) Wzy_C_2 PF11846.8 EMR65283.1 - 0.00048 20.1 8.3 0.22 11.5 1.2 5.0 3 1 2 5 5 5 1 Virulence factor membrane-bound polymerase, C-terminal TPR_21 PF09976.9 EMR65283.1 - 0.0011 18.7 2.2 0.0011 18.7 2.2 4.1 4 1 1 5 5 4 2 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 EMR65283.1 - 0.0013 19.0 19.4 1 9.7 0.0 8.0 5 1 5 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMR65283.1 - 0.012 15.3 9.8 1.2 8.8 0.1 5.5 7 0 0 7 7 6 0 TPR repeat ChAPs PF09295.10 EMR65283.1 - 0.021 13.9 1.3 0.088 11.8 0.4 2.2 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) YfiO PF13525.6 EMR65283.1 - 0.085 12.6 0.2 2.7 7.7 0.0 3.3 4 1 1 5 5 5 0 Outer membrane lipoprotein TPR_7 PF13176.6 EMR65283.1 - 0.15 12.2 5.6 29 5.0 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 EMR65283.1 - 0.18 10.5 4.5 3.7 6.2 0.0 3.8 3 1 1 5 5 5 0 Protein of unknown function (DUF3808) RrnaAD PF00398.20 EMR65284.1 - 1.9e-63 214.0 0.0 2.5e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EMR65284.1 - 2.4e-07 31.3 0.0 5.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR65284.1 - 6e-06 26.8 0.0 1.3e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR65284.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EMR65284.1 - 0.00049 19.9 0.0 0.00087 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EMR65284.1 - 0.00061 19.2 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EMR65284.1 - 0.00097 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR65284.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR65284.1 - 0.0032 18.2 0.0 0.0072 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EMR65284.1 - 0.028 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 EMR65284.1 - 0.052 12.9 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EMR65284.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 EMR65284.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 EMR65284.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 EMR65284.1 - 0.18 11.4 0.0 0.61 9.7 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DREV PF05219.12 EMR65284.1 - 0.2 10.7 0.0 0.49 9.4 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase ARGLU PF15346.6 EMR65284.1 - 1.8 8.4 4.9 19 5.1 0.8 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 FAD_binding_3 PF01494.19 EMR65285.1 - 1.2e-21 77.4 0.0 4.5e-21 75.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR65285.1 - 2.5e-05 23.7 0.1 0.0098 15.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR65285.1 - 0.00015 22.3 1.4 0.0084 16.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR65285.1 - 0.00018 21.2 0.1 0.0029 17.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR65285.1 - 0.00058 19.2 0.4 0.12 11.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR65285.1 - 0.0011 19.2 0.1 0.0031 17.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR65285.1 - 0.0024 17.0 0.2 0.022 13.8 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EMR65286.1 - 1.8e-49 168.9 0.2 2.2e-49 168.6 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMR65286.1 - 0.00099 19.2 0.0 0.0023 18.0 0.0 1.7 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain IF-2B PF01008.17 EMR65287.1 - 6.5e-22 78.0 0.0 7.4e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Aldo_ket_red PF00248.21 EMR65288.1 - 3.6e-39 134.7 0.0 5.4e-38 130.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 EMR65289.1 - 1.4e-31 109.8 0.0 1.7e-15 56.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SprT-like PF10263.9 EMR65290.1 - 4.9e-27 94.0 3.1 9e-27 93.2 3.1 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EMR65290.1 - 5.1e-09 35.9 6.1 9.4e-09 35.0 6.1 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF4379 PF14311.6 EMR65290.1 - 0.78 10.2 4.5 1.7 9.0 1.4 2.7 2 0 0 2 2 2 0 Probable Zinc-ribbon domain DASH_Dam1 PF08653.10 EMR65291.1 - 5.2e-27 93.4 1.8 8.3e-27 92.8 1.8 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 Silic_transp PF03842.13 EMR65291.1 - 0.035 12.4 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Silicon transporter Coatomer_WDAD PF04053.14 EMR65292.1 - 1.9e-146 488.6 0.0 3.5e-146 487.8 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 EMR65292.1 - 2.8e-100 335.9 0.0 3.6e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EMR65292.1 - 1e-36 124.3 21.7 1.8e-07 31.7 0.3 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR65292.1 - 2.6e-05 24.5 1.0 4.7 7.6 0.0 5.8 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EMR65292.1 - 0.026 14.4 0.0 0.17 11.7 0.0 2.2 1 1 1 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.8 EMR65292.1 - 0.16 10.6 4.1 7 5.2 0.8 3.5 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Hva1_TUDOR PF11160.8 EMR65293.1 - 2.1e-08 34.2 1.0 2.8e-08 33.8 1.0 1.2 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain SnoaL PF07366.12 EMR65293.1 - 0.14 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase HIT PF01230.23 EMR65294.1 - 3.3e-22 79.1 0.1 4.7e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EMR65294.1 - 3e-13 50.3 0.0 3.9e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EMR65294.1 - 4.5e-05 23.3 0.0 7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.6 EMR65294.1 - 0.068 13.6 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Fez1 PF06818.15 EMR65295.1 - 3e-05 24.6 32.9 0.00094 19.7 21.8 2.3 1 1 1 2 2 2 2 Fez1 FPP PF05911.11 EMR65295.1 - 0.00066 18.0 22.1 0.0009 17.6 22.1 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil CLZ PF16526.5 EMR65295.1 - 0.00093 19.5 19.8 0.12 12.7 3.3 3.0 2 1 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pox_A_type_inc PF04508.12 EMR65295.1 - 0.0039 17.0 0.0 0.014 15.2 0.0 2.0 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat DUF5531 PF17671.1 EMR65295.1 - 0.015 15.2 2.5 0.015 15.2 2.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5531) THOC7 PF05615.13 EMR65295.1 - 0.036 14.3 27.2 0.19 12.0 11.1 3.1 1 1 1 2 2 2 0 Tho complex subunit 7 bZIP_2 PF07716.15 EMR65295.1 - 0.071 13.2 1.0 0.071 13.2 1.0 5.2 4 1 1 5 5 5 0 Basic region leucine zipper HsbA PF12296.8 EMR65295.1 - 0.086 13.3 0.6 0.086 13.3 0.6 2.4 1 1 0 2 2 2 0 Hydrophobic surface binding protein A MAD PF05557.13 EMR65295.1 - 0.22 9.8 31.7 0.31 9.4 31.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein GAS PF13851.6 EMR65295.1 - 0.25 10.7 36.2 0.67 9.3 10.0 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EMR65295.1 - 0.26 10.2 38.8 0.14 11.1 20.2 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein MscS_porin PF12795.7 EMR65295.1 - 0.26 10.8 37.4 1.4 8.4 36.5 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF4094 PF13334.6 EMR65295.1 - 0.31 11.5 23.0 0.59 10.6 5.5 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Tropomyosin_1 PF12718.7 EMR65295.1 - 0.7 10.0 38.7 0.043 14.0 12.7 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF724 PF05266.14 EMR65295.1 - 0.73 9.6 30.5 1.1 9.0 13.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Sulfatase_C PF14707.6 EMR65295.1 - 1 10.1 9.1 0.6 10.8 2.2 2.6 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase KASH_CCD PF14662.6 EMR65295.1 - 1.2 9.0 33.9 3.7 7.3 20.7 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 EMR65295.1 - 1.2 9.2 34.5 1.3 9.1 10.1 2.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.12 EMR65295.1 - 1.4 6.9 33.7 1 7.5 5.6 2.0 1 1 1 2 2 2 0 HOOK protein Mga PF05043.13 EMR65295.1 - 1.5 9.5 5.3 2 9.1 0.6 3.0 1 1 2 3 3 3 0 Mga helix-turn-helix domain Pro_Al_protease PF02983.14 EMR65295.1 - 1.6 8.8 4.7 20 5.4 0.3 3.1 2 1 0 2 2 2 0 Alpha-lytic protease prodomain DUF1664 PF07889.12 EMR65295.1 - 2.1 8.4 19.0 10 6.2 7.5 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EMR65295.1 - 2.4 8.4 20.3 0.19 11.9 0.5 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 EMR65295.1 - 2.5 7.1 34.9 0.097 11.7 17.4 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 EMR65295.1 - 2.6 5.4 35.5 0.095 10.2 26.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CALCOCO1 PF07888.11 EMR65295.1 - 2.7 6.7 36.6 0.33 9.8 22.0 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.21 EMR65295.1 - 3.1 7.3 31.9 8.4 5.9 32.0 1.6 1 1 0 1 1 1 0 Intermediate filament protein DLP_helical PF18709.1 EMR65295.1 - 3.5 6.8 21.9 6 6.0 9.1 2.7 1 1 1 2 2 2 0 Dynamin-like helical domain End3 PF12761.7 EMR65295.1 - 3.7 7.7 31.6 2.6 8.2 15.4 2.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 HAUS-augmin3 PF14932.6 EMR65295.1 - 4 6.9 30.1 0.083 12.5 10.8 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 EMR65295.1 - 4.1 7.9 42.5 4.5 7.8 21.0 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region Tropomyosin PF00261.20 EMR65295.1 - 4.1 6.7 37.7 0.12 11.8 24.2 2.5 1 1 1 2 2 2 0 Tropomyosin DUF5082 PF16888.5 EMR65295.1 - 4.3 7.6 29.9 1 9.7 5.0 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) ABC_tran_CTD PF16326.5 EMR65295.1 - 5.3 7.4 35.7 0.8 10.0 5.4 4.6 2 1 3 5 5 5 0 ABC transporter C-terminal domain EzrA PF06160.12 EMR65295.1 - 5.5 5.0 28.4 11 4.1 28.4 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 EMR65295.1 - 5.6 6.3 35.4 4.5 6.6 12.9 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Lectin_N PF03954.14 EMR65295.1 - 6.6 6.5 19.0 0.28 10.9 8.4 2.9 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain VPS11_C PF12451.8 EMR65295.1 - 6.8 7.0 7.9 4.2 7.7 0.7 3.5 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal FlaC_arch PF05377.11 EMR65295.1 - 7.1 7.1 15.2 1.1 9.6 0.3 4.6 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 EMR65295.1 - 7.4 6.6 39.6 3.1 7.9 19.9 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein E2R135 PF11570.8 EMR65295.1 - 8.3 6.7 16.7 0.3 11.4 0.5 3.7 1 1 1 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 BST2 PF16716.5 EMR65295.1 - 8.4 7.1 30.2 0.18 12.4 7.1 3.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 HMMR_N PF15905.5 EMR65295.1 - 8.7 5.7 36.1 6.6 6.1 2.9 2.2 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CSN8_PSD8_EIF3K PF10075.9 EMR65296.1 - 2.6e-18 66.4 0.0 4.1e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EMR65296.1 - 0.095 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family Filament_head PF04732.14 EMR65296.1 - 1.1 10.2 9.3 5.4 8.0 0.1 3.0 2 1 1 3 3 3 0 Intermediate filament head (DNA binding) region Sel1 PF08238.12 EMR65297.1 - 1.4e-17 63.7 18.6 6.4e-08 33.0 0.2 6.8 6 0 0 6 6 6 5 Sel1 repeat N6-adenineMlase PF10237.9 EMR65298.1 - 4.6e-55 185.8 0.0 5.6e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Mog1 PF04603.12 EMR65299.1 - 2.3e-37 128.5 0.0 2.7e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein NAD_binding_8 PF13450.6 EMR65299.1 - 0.086 13.1 0.0 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Peptidase_S8 PF00082.22 EMR65300.1 - 1.9e-31 109.4 12.8 3.2e-31 108.7 12.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR65300.1 - 1.1e-10 42.1 0.1 7e-10 39.4 0.1 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 Lactamase_B PF00753.27 EMR65301.1 - 2.9e-19 69.9 4.6 4.6e-19 69.2 4.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EMR65301.1 - 4.7e-17 61.7 0.1 9.2e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EMR65301.1 - 5.9e-08 32.5 0.5 9.6e-08 31.8 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PCI PF01399.27 EMR65302.1 - 5.6e-06 26.8 0.0 1.6e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EMR65302.1 - 2.1e-05 24.0 0.3 4.5e-05 23.0 0.3 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix ANAPC5 PF12862.7 EMR65302.1 - 0.57 10.3 5.9 2.7 8.1 2.0 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 CRAL_TRIO PF00650.20 EMR65303.1 - 1.7e-40 138.3 0.0 2.9e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMR65303.1 - 2.6e-14 53.1 0.3 8.2e-14 51.5 0.3 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EMR65303.1 - 2.5e-07 30.9 0.0 4.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Gaa1 PF04114.14 EMR65304.1 - 2.6e-160 534.8 0.0 5.7e-160 533.6 0.0 1.5 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Glyco_hydro_17 PF00332.18 EMR65305.1 - 6.5e-08 32.5 0.2 1.4e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 SOG2 PF10428.9 EMR65305.1 - 0.017 14.4 6.5 0.023 13.9 6.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EMR65305.1 - 0.086 12.7 1.0 0.08 12.8 1.0 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 EMR65305.1 - 0.79 8.3 6.1 1 8.0 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aconitase PF00330.20 EMR65306.1 - 2.8e-146 488.2 0.0 3.6e-146 487.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMR65306.1 - 3.6e-43 147.0 0.0 6.2e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ytp1 PF10355.9 EMR65307.1 - 5.9e-115 383.2 4.5 8.7e-115 382.7 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EMR65307.1 - 3.4e-33 113.6 5.9 3.4e-33 113.6 5.9 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF5504 PF17608.2 EMR65307.1 - 0.013 15.6 3.9 0.16 12.1 2.6 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5504) Ca_hom_mod PF14798.6 EMR65307.1 - 0.11 11.5 0.3 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Calcium homeostasis modulator SUIM_assoc PF16619.5 EMR65308.1 - 0.0083 16.2 1.3 0.037 14.1 1.3 2.1 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RAM PF15320.6 EMR65308.1 - 0.034 14.7 0.9 0.62 10.7 0.1 2.4 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein PEHE PF15275.6 EMR65308.1 - 0.48 11.1 4.2 2.9 8.5 0.0 2.6 2 1 0 2 2 2 0 PEHE domain SPX PF03105.19 EMR65308.1 - 0.63 9.9 6.8 0.97 9.3 6.8 1.3 1 0 0 1 1 1 0 SPX domain Mito_carr PF00153.27 EMR65309.1 - 3.5e-27 94.1 1.0 5.7e-14 51.8 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_9_N PF15420.6 EMR65309.1 - 0.0025 17.9 2.1 0.2 11.6 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta-hydrolase family N-terminus DMT_YdcZ PF04657.13 EMR65309.1 - 0.018 15.3 2.4 0.22 11.8 0.4 2.3 2 0 0 2 2 2 0 Putative inner membrane exporter, YdcZ Heliorhodopsin PF18761.1 EMR65309.1 - 0.071 12.4 0.5 2.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Heliorhodopsin DUF3054 PF11255.8 EMR65309.1 - 0.17 12.4 1.4 0.74 10.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) Lgl_C PF08596.10 EMR65310.1 - 1.9e-117 392.3 0.0 3e-117 391.7 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EMR65310.1 - 8.1e-06 26.5 5.5 0.001 19.8 0.3 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR65310.1 - 3.4e-05 24.0 0.0 0.039 14.3 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR65310.1 - 0.2 10.3 0.0 12 4.3 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF4930 PF16284.5 EMR65310.1 - 0.23 11.4 0.2 0.54 10.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4930) Histidinol_dh PF00815.20 EMR65311.1 - 0.095 11.7 0.5 0.15 11.1 0.5 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase NAD_binding_10 PF13460.6 EMR65312.1 - 1.1e-07 32.0 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR65312.1 - 8.6e-07 28.7 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR65312.1 - 1.6e-05 24.5 0.2 3.1e-05 23.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR65312.1 - 1.6e-05 24.0 0.1 0.0001 21.5 0.1 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMR65312.1 - 0.046 12.8 0.1 0.16 11.0 0.1 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain XRCC1_N PF01834.16 EMR65312.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 XRCC1 N terminal domain zf-C2H2_jaz PF12171.8 EMR65313.1 - 3e-09 36.9 0.1 5e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding GH-E PF14410.6 EMR65313.1 - 0.0019 18.6 0.5 0.01 16.2 0.3 2.0 2 0 0 2 2 2 1 HNH/ENDO VII superfamily nuclease with conserved GHE residues zf-C2H2_2 PF12756.7 EMR65313.1 - 0.057 13.8 0.1 0.12 12.7 0.1 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EMR65313.1 - 0.072 14.0 0.3 0.25 12.3 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger SNF2_N PF00176.23 EMR65314.1 - 9.7e-58 195.5 0.0 1.5e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EMR65314.1 - 2.1e-56 191.0 0.1 8.9e-56 188.9 0.3 1.9 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 EMR65314.1 - 2.2e-16 60.2 0.0 6.6e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR65314.1 - 5e-09 36.4 0.0 9.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMR65314.1 - 7.8e-06 25.8 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EMR65314.1 - 0.0003 20.1 0.0 0.0014 17.8 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EMR65314.1 - 0.024 14.3 0.1 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Peptidase_S66 PF02016.15 EMR65316.1 - 4.6e-25 88.1 0.0 7.6e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 EMR65316.1 - 6.3e-23 81.6 0.0 1.5e-22 80.4 0.0 1.7 1 1 0 1 1 1 1 LD-carboxypeptidase C-terminal domain Glucan_synthase PF02364.15 EMR65317.1 - 0 1369.5 0.0 0 1368.9 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EMR65317.1 - 1.2e-41 142.0 0.4 4.8e-41 140.1 0.4 2.1 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Ribosomal_L18p PF00861.22 EMR65318.1 - 0.17 12.3 1.6 1.9 8.9 0.1 2.4 2 1 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Glyco_transf_24 PF18404.1 EMR65319.1 - 4.2e-148 492.0 1.5 6.2e-148 491.4 1.5 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 EMR65319.1 - 2.2e-53 181.3 0.3 3.8e-52 177.3 0.5 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_14 PF18402.1 EMR65319.1 - 1.8e-52 178.8 0.0 1e-50 173.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EMR65319.1 - 1.6e-41 140.9 0.0 3e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EMR65319.1 - 0.0001 22.0 0.1 0.00021 20.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Aminotran_1_2 PF00155.21 EMR65320.1 - 2.9e-39 135.3 0.0 3.4e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMR65320.1 - 0.0091 14.6 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Acetyltransf_7 PF13508.7 EMR65321.1 - 4.7e-08 33.3 0.0 8.1e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR65321.1 - 1.6e-07 31.6 0.0 2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR65321.1 - 0.00091 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rhomboid PF01694.22 EMR65322.1 - 2.2e-13 50.5 11.8 2.2e-13 50.5 11.8 1.4 2 0 0 2 2 2 1 Rhomboid family AAA PF00004.29 EMR65323.1 - 5.4e-10 39.8 0.0 2.2e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMR65323.1 - 0.057 13.4 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EMR65323.1 - 0.13 12.6 0.1 0.32 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMR65323.1 - 0.25 11.6 0.2 0.63 10.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain UCH PF00443.29 EMR65324.1 - 1.5e-23 83.7 5.3 1.8e-15 57.1 1.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMR65324.1 - 3e-10 40.2 10.7 3.8e-10 39.9 4.0 2.5 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EMR65324.1 - 8.6e-05 22.8 0.4 8.6e-05 22.8 0.4 2.3 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Rsa3 PF14615.6 EMR65325.1 - 1.1e-21 76.1 0.3 1.4e-21 75.7 0.3 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DUF2207 PF09972.9 EMR65326.1 - 0.0026 16.6 0.1 0.0033 16.3 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Ribosomal_S8e PF01201.22 EMR65327.1 - 8.2e-55 184.7 1.7 9.3e-55 184.5 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e An_peroxidase PF03098.15 EMR65327.1 - 0.017 13.7 0.9 0.018 13.6 0.1 1.4 2 0 0 2 2 2 0 Animal haem peroxidase AA_permease_2 PF13520.6 EMR65328.1 - 6.6e-55 186.6 44.8 7.5e-55 186.5 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR65328.1 - 9.6e-26 90.4 34.6 1.2e-25 90.0 34.6 1.1 1 0 0 1 1 1 1 Amino acid permease Ctf8 PF09696.10 EMR65329.1 - 1.4e-25 90.3 0.7 1.5e-25 90.2 0.7 1.0 1 0 0 1 1 1 1 Ctf8 Ribosomal_S6e PF01092.19 EMR65330.1 - 7.3e-59 197.2 0.1 1.4e-58 196.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Atg14 PF10186.9 EMR65330.1 - 1.3 8.0 7.5 2.1 7.4 7.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 WW PF00397.26 EMR65331.1 - 1.2e-10 41.3 0.4 2.5e-10 40.3 0.4 1.6 1 0 0 1 1 1 1 WW domain Tubulin PF00091.25 EMR65332.1 - 3.8e-68 229.6 0.0 5.6e-68 229.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMR65332.1 - 6.4e-49 165.3 0.0 1.1e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EMR65332.1 - 0.0023 17.7 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Cellulase PF00150.18 EMR65334.1 - 4e-54 184.0 4.3 4.8e-54 183.7 4.3 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short_C2 PF13561.6 EMR65335.1 - 1.6e-53 181.7 1.7 2.1e-53 181.3 1.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR65335.1 - 1.1e-38 132.7 2.1 1.4e-38 132.3 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR65335.1 - 3.6e-11 43.3 1.0 5.3e-11 42.8 1.0 1.2 1 0 0 1 1 1 1 KR domain DUF3104 PF11302.8 EMR65335.1 - 0.044 13.5 0.3 12 5.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3104) ADH_zinc_N PF00107.26 EMR65335.1 - 0.047 13.7 0.3 0.66 10.0 0.1 2.3 1 1 1 2 2 2 0 Zinc-binding dehydrogenase DUF3194 PF11419.8 EMR65335.1 - 0.15 12.4 0.5 9 6.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3194) TFIID_30kDa PF03540.13 EMR65336.1 - 1.8e-23 82.2 0.4 1.8e-23 82.2 0.4 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EMR65336.1 - 0.043 14.4 1.5 0.088 13.4 1.5 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pribosyltran_N PF13793.6 EMR65337.1 - 1.5e-43 147.5 1.0 6.3e-43 145.4 0.1 2.4 3 1 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EMR65337.1 - 7.6e-39 133.6 6.1 2.3e-33 115.8 4.3 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EMR65337.1 - 2.6e-16 59.5 1.8 6.2e-16 58.3 1.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMR65337.1 - 0.012 15.1 0.4 0.021 14.3 0.4 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF4392 PF14336.6 EMR65337.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Chlorosome_CsmC PF11098.8 EMR65337.1 - 0.18 11.8 3.8 0.25 11.3 2.8 1.8 1 1 1 2 2 2 0 Chlorosome envelope protein C AIP3 PF03915.13 EMR65338.1 - 1.7e-159 531.4 15.5 2e-159 531.1 15.5 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.14 EMR65338.1 - 0.012 15.3 0.8 0.012 15.3 0.8 2.8 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain MIP-T3_C PF17749.1 EMR65338.1 - 0.015 15.2 8.4 1.1 9.2 3.8 3.1 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Spore_III_AB PF09548.10 EMR65338.1 - 0.015 15.4 0.8 0.015 15.4 0.8 2.7 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Baculo_p24 PF05073.12 EMR65338.1 - 0.037 13.8 3.1 0.12 12.1 0.1 2.7 3 0 0 3 3 3 0 Baculovirus P24 capsid protein Ribosomal_S13 PF00416.22 EMR65338.1 - 0.069 13.6 0.8 0.24 11.8 0.8 1.9 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Sec34 PF04136.15 EMR65338.1 - 0.11 12.3 6.9 10 6.0 0.0 3.6 2 1 1 3 3 3 0 Sec34-like family DUF2935 PF11155.8 EMR65338.1 - 0.17 12.2 0.8 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) DUF1664 PF07889.12 EMR65338.1 - 0.37 10.8 9.4 0.56 10.3 0.8 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) RasGAP_C PF03836.15 EMR65338.1 - 0.38 10.9 5.3 2.4 8.3 1.3 3.5 2 1 1 3 3 3 0 RasGAP C-terminus CdvA PF18822.1 EMR65338.1 - 2.3 8.1 9.7 1.6 8.5 0.0 4.2 3 1 0 4 4 4 0 CdvA-like coiled-coil domain Epimerase PF01370.21 EMR65340.1 - 2.3e-17 63.3 0.0 3.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR65340.1 - 4.4e-12 45.6 0.0 5.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMR65340.1 - 6.6e-09 35.9 0.1 1.7e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMR65340.1 - 1e-07 31.4 0.1 5.4e-07 29.0 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EMR65340.1 - 1.7e-07 31.0 0.0 3.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMR65340.1 - 5.9e-05 22.6 0.0 0.00015 21.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR65340.1 - 7.8e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR65340.1 - 0.00039 19.6 0.0 0.00053 19.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EMR65340.1 - 0.0012 18.4 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short_C2 PF13561.6 EMR65340.1 - 0.0048 16.5 0.0 0.019 14.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 EMR65340.1 - 0.011 16.3 0.0 0.032 14.8 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_S19 PF00203.21 EMR65341.1 - 1.4e-25 89.0 0.0 1.9e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ufd2P_core PF10408.9 EMR65342.1 - 1.3e-199 664.9 0.0 1.5e-199 664.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EMR65342.1 - 1.2e-19 70.2 0.4 3.5e-19 68.7 0.4 1.8 1 0 0 1 1 1 1 U-box domain DASH_Duo1 PF08651.10 EMR65342.1 - 0.1 12.4 1.2 6.6 6.6 0.2 2.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 DHR10 PF18595.1 EMR65342.1 - 0.23 11.5 7.0 4.2 7.5 0.2 3.1 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Med9 PF07544.13 EMR65342.1 - 0.64 10.1 5.2 8.5 6.5 0.0 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ABC_tran_CTD PF16326.5 EMR65342.1 - 2.2 8.6 9.9 0.24 11.7 0.9 3.2 3 0 0 3 3 3 0 ABC transporter C-terminal domain CCDC-167 PF15188.6 EMR65342.1 - 4.8 7.6 5.1 23 5.4 0.2 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 RabGAP-TBC PF00566.18 EMR65343.1 - 1e-48 165.9 0.2 1e-46 159.3 0.0 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Jnk-SapK_ap_N PF09744.9 EMR65343.1 - 0.0016 18.7 15.5 0.0016 18.7 15.5 3.3 3 1 1 4 4 4 1 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 EMR65343.1 - 0.011 15.9 5.9 0.011 15.9 5.9 3.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 IFP_35_N PF07334.13 EMR65343.1 - 0.24 11.5 8.0 0.91 9.6 1.0 3.0 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Mod_r PF07200.13 EMR65343.1 - 0.36 10.9 21.9 0.37 10.9 10.4 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.18 EMR65343.1 - 1.6 9.0 16.5 1.4 9.2 1.7 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper TolA_bind_tri PF16331.5 EMR65343.1 - 2.5 8.2 12.2 0.22 11.6 4.7 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF4094 PF13334.6 EMR65343.1 - 3.6 8.1 4.9 6.8 7.2 2.9 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) FixQ PF05545.11 EMR65344.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.5 2 1 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4131 PF13567.6 EMR65344.1 - 2.5 7.7 5.3 3.8 7.1 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) EF-hand_4 PF12763.7 EMR65346.1 - 3.2e-30 104.2 0.0 2.2e-11 43.6 0.0 3.6 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EMR65346.1 - 4e-10 40.0 0.0 2.3e-05 24.8 0.0 4.7 5 0 0 5 5 4 1 EF-hand domain pair EF-hand_1 PF00036.32 EMR65346.1 - 1e-05 24.7 0.1 34 4.3 0.0 5.9 6 0 0 6 6 6 0 EF hand UBA PF00627.31 EMR65346.1 - 7.1e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 EMR65346.1 - 0.00014 21.5 0.0 3.1 7.9 0.0 4.8 5 0 0 5 5 4 1 EF-hand domain CENP-F_leu_zip PF10473.9 EMR65346.1 - 0.0016 18.5 12.5 0.0016 18.5 12.5 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 EMR65346.1 - 0.0033 18.3 10.1 0.0033 18.3 10.1 3.5 1 1 3 4 4 4 2 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 EMR65346.1 - 0.0041 17.3 28.9 0.02 15.1 4.2 3.2 1 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF4472 PF14739.6 EMR65346.1 - 0.0087 16.8 8.7 0.0087 16.8 8.7 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF4472) Spc7 PF08317.11 EMR65346.1 - 0.012 14.5 32.3 0.089 11.7 17.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein LPP PF04728.13 EMR65346.1 - 0.017 15.5 3.0 0.017 15.5 3.0 4.4 3 1 0 3 3 3 0 Lipoprotein leucine-zipper APG6_N PF17675.1 EMR65346.1 - 0.02 15.4 28.8 0.091 13.3 20.8 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 EMR65346.1 - 0.021 14.9 33.6 0.67 10.1 2.4 4.5 1 1 3 4 4 4 0 TolA binding protein trimerisation DUF1664 PF07889.12 EMR65346.1 - 0.046 13.8 19.8 0.017 15.2 8.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 EMR65346.1 - 0.05 12.1 4.4 0.077 11.5 4.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3243 PF11588.8 EMR65346.1 - 0.056 13.8 0.1 2.4 8.6 0.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF3243) DUF3584 PF12128.8 EMR65346.1 - 0.09 10.3 30.8 0.12 9.8 30.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ZapB PF06005.12 EMR65346.1 - 0.096 13.1 29.2 1.4 9.4 0.0 4.1 2 1 2 4 4 4 0 Cell division protein ZapB IFT57 PF10498.9 EMR65346.1 - 0.1 11.5 21.5 0.031 13.3 17.9 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 EMR65346.1 - 0.11 12.6 33.7 0.28 11.2 18.9 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 EMR65346.1 - 0.14 11.8 30.8 0.27 10.9 30.8 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 EMR65346.1 - 0.23 10.8 31.3 0.29 10.5 11.6 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 EMR65346.1 - 0.25 10.6 31.8 0.084 12.2 11.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 EMR65346.1 - 0.59 10.4 29.3 1.2 9.4 9.1 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 EMR65346.1 - 0.6 8.9 5.1 0.98 8.3 5.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ATG16 PF08614.11 EMR65346.1 - 0.64 10.2 38.8 0.059 13.6 9.7 2.8 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) Med30 PF11315.8 EMR65346.1 - 0.97 9.6 13.0 0.74 10.0 11.2 1.7 1 1 0 1 1 1 0 Mediator complex subunit 30 SYCE1 PF15233.6 EMR65346.1 - 1.3 9.1 26.4 0.13 12.3 17.5 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Golgin_A5 PF09787.9 EMR65346.1 - 1.3 8.4 30.6 0.26 10.7 24.6 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 Scaffolding_pro PF11418.8 EMR65346.1 - 1.6 9.3 5.0 5.5 7.6 0.3 2.7 1 1 1 2 2 2 0 Phi29 scaffolding protein Laminin_I PF06008.14 EMR65346.1 - 1.8 8.2 27.0 0.62 9.7 5.5 2.7 1 1 1 2 2 2 0 Laminin Domain I KASH_CCD PF14662.6 EMR65346.1 - 1.9 8.3 25.9 3.2 7.5 25.9 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4047 PF13256.6 EMR65346.1 - 1.9 8.7 9.5 0.7 10.1 6.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) HrpB7 PF09486.10 EMR65346.1 - 2.3 8.6 16.8 1.4 9.3 14.6 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HAP1_N PF04849.13 EMR65346.1 - 2.6 7.2 28.5 3.8 6.6 17.7 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region AAA_13 PF13166.6 EMR65346.1 - 3.2 6.3 23.5 5.8 5.4 23.5 1.4 1 0 0 1 1 1 0 AAA domain EzrA PF06160.12 EMR65346.1 - 3.7 5.6 23.4 0.49 8.5 16.1 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 EMR65346.1 - 3.8 8.0 15.3 17 5.9 0.2 4.4 2 2 1 4 4 4 0 Flagella accessory protein C (FlaC) ERM PF00769.19 EMR65346.1 - 3.8 7.3 32.1 1.1 9.0 11.5 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family YkyA PF10368.9 EMR65346.1 - 4.9 6.8 24.0 0.4 10.3 16.5 2.3 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein GP41 PF00517.17 EMR65346.1 - 4.9 7.0 7.7 4.5 7.1 0.8 2.3 2 0 0 2 2 2 0 Retroviral envelope protein FAD-SLDH PF12318.8 EMR65346.1 - 6.2 6.9 6.2 8.5 6.4 0.3 2.7 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Occludin_ELL PF07303.13 EMR65346.1 - 6.7 7.5 14.5 5.4 7.8 7.2 3.2 2 1 1 3 3 3 0 Occludin homology domain YabA PF06156.13 EMR65346.1 - 7.9 7.2 22.9 2.2 9.0 2.7 3.1 1 1 2 3 3 3 0 Initiation control protein YabA UPF0242 PF06785.11 EMR65347.1 - 0.0097 16.0 0.8 0.0097 16.0 0.8 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EMR65347.1 - 0.016 15.8 3.3 0.016 15.8 3.3 2.5 1 1 1 2 2 2 0 SlyX Spc29 PF17082.5 EMR65347.1 - 0.056 13.3 5.2 0.068 13.0 1.0 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 UME PF08064.13 EMR65347.1 - 0.078 12.9 0.5 0.13 12.2 0.5 1.4 1 0 0 1 1 1 0 UME (NUC010) domain DUF4407 PF14362.6 EMR65347.1 - 0.13 11.6 8.7 0.14 11.5 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Swi5 PF07061.11 EMR65347.1 - 0.22 11.6 4.9 2.4 8.3 0.9 2.3 1 1 1 2 2 2 0 Swi5 DUF16 PF01519.16 EMR65347.1 - 0.22 12.0 10.7 0.23 12.0 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 EMR65347.1 - 0.22 12.0 7.6 7.3 7.1 4.1 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein USP8_interact PF08941.10 EMR65347.1 - 0.25 11.1 4.0 0.4 10.5 4.0 1.4 1 0 0 1 1 1 0 USP8 interacting DUF1732 PF08340.11 EMR65347.1 - 0.69 9.9 7.2 0.46 10.5 1.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) FUSC PF04632.12 EMR65347.1 - 0.71 8.3 4.6 0.86 8.1 4.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM76 PF16046.5 EMR65347.1 - 2 7.7 6.6 2.4 7.4 6.6 1.1 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 EMR65347.1 - 4.3 7.5 8.1 0.96 9.6 2.0 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 EMR65347.1 - 4.5 7.7 9.9 3.5 8.0 0.9 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain DNase_NucA_NucB PF14040.6 EMR65348.1 - 7.6e-36 123.0 2.9 1.4e-35 122.1 2.9 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF913 PF06025.12 EMR65349.1 - 4.9e-129 430.5 0.0 4.9e-129 430.5 0.0 6.3 7 0 0 7 7 7 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EMR65349.1 - 8e-124 413.7 3.9 8e-124 413.7 3.9 4.3 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EMR65349.1 - 8.5e-93 311.2 0.0 1.4e-92 310.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EMR65349.1 - 2.8e-23 80.6 21.0 9.8e-08 31.2 1.6 4.0 3 1 0 3 3 3 3 Ubiquitin binding region U79_P34 PF03064.16 EMR65349.1 - 0.65 9.3 8.8 2 7.7 8.8 1.8 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CAF-1_p150 PF11600.8 EMR65349.1 - 8.3 6.1 32.6 0.24 11.1 24.5 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal p450 PF00067.22 EMR65353.1 - 5.2e-19 68.3 0.1 2.4e-18 66.1 0.1 1.8 1 1 0 1 1 1 1 Cytochrome P450 GPI2 PF06432.11 EMR65354.1 - 3.1e-133 443.5 4.3 3.7e-133 443.3 4.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase VCBS PF13517.6 EMR65355.1 - 8.3e-05 23.1 3.9 0.0061 17.1 0.3 4.4 1 1 3 5 5 5 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EMR65355.1 - 0.00035 20.6 1.0 0.47 10.6 0.1 3.5 3 0 0 3 3 3 2 FG-GAP repeat P_proprotein PF01483.20 EMR65355.1 - 0.0026 17.8 0.9 23 5.1 0.0 4.3 3 1 1 4 4 4 0 Proprotein convertase P-domain FaeA PF04703.12 EMR65355.1 - 0.032 14.6 0.8 20 5.7 0.0 3.2 3 0 0 3 3 3 0 FaeA-like protein EF-hand_1 PF00036.32 EMR65355.1 - 0.068 12.8 0.1 0.89 9.3 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EMR65355.1 - 0.088 12.8 0.1 2.2 8.4 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain DUF3642 PF12182.8 EMR65355.1 - 0.13 12.5 0.7 0.34 11.2 0.2 1.9 2 0 0 2 2 2 0 Bacterial lipoprotein DUF756 PF05506.12 EMR65355.1 - 0.54 11.2 4.3 20 6.2 1.5 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF756) adh_short PF00106.25 EMR65356.1 - 2e-09 37.2 0.0 0.0019 17.7 0.0 3.1 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65356.1 - 1.5e-07 31.2 0.0 0.0005 19.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR65356.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Annexin PF00191.20 EMR65357.1 - 7.5e-16 58.0 0.0 0.0023 17.9 0.0 4.4 4 0 0 4 4 4 4 Annexin DUF5617 PF18493.1 EMR65357.1 - 0.075 13.1 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) Cyt-b5 PF00173.28 EMR65358.1 - 4.9e-18 65.1 0.0 6.6e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.16 EMR65359.1 - 1.1e-11 44.2 30.1 1.1e-11 44.2 30.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65359.1 - 1.3e-08 34.2 7.1 1.3e-08 34.2 7.1 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter UNC-93 PF05978.16 EMR65359.1 - 2.4e-08 33.8 3.2 7e-08 32.3 3.2 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 ATPase_gene1 PF09527.10 EMR65359.1 - 0.5 10.6 12.6 0.51 10.5 2.4 3.5 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Amidohydro_2 PF04909.14 EMR65360.1 - 2.5e-37 129.2 0.4 3.4e-37 128.8 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase DAO PF01266.24 EMR65361.1 - 1.3e-34 120.4 0.0 1.4e-34 120.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR65361.1 - 0.0011 18.2 0.0 0.94 8.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 EMR65361.1 - 0.0084 16.7 0.6 0.028 15.0 0.1 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 EMR65361.1 - 0.0089 16.0 0.2 1.3 9.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 EMR65361.1 - 0.048 12.4 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 MCRA family Epimerase PF01370.21 EMR65361.1 - 0.091 12.2 0.0 2.7 7.4 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.6 EMR65361.1 - 0.16 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EMR65361.1 - 0.17 10.7 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mod_r PF07200.13 EMR65361.1 - 0.21 11.7 0.1 0.32 11.1 0.1 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein GIDA PF01134.22 EMR65361.1 - 0.23 10.5 0.0 2.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NIBRIN_BRCT_II PF16508.5 EMR65362.1 - 2e-37 128.2 0.0 1.1e-36 125.7 0.0 2.3 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 EMR65362.1 - 1.4e-09 38.1 0.0 3.5e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain NAM-associated PF14303.6 EMR65362.1 - 0.00087 20.0 3.4 34 5.1 0.0 4.1 2 2 1 3 3 3 1 No apical meristem-associated C-terminal domain RTT107_BRCT_5 PF16770.5 EMR65362.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 EMR65362.1 - 0.11 12.9 0.1 0.93 9.9 0.1 2.5 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RRM_1 PF00076.22 EMR65363.1 - 8.9e-17 60.7 0.0 1.3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.9 EMR65364.1 - 5.5e-46 155.2 1.7 6.2e-46 155.0 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 TPR_1 PF00515.28 EMR65365.1 - 1.2e-40 135.7 15.6 2.6e-07 30.2 0.0 9.8 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 EMR65365.1 - 7e-38 125.7 22.1 1.1e-05 25.1 0.1 10.4 10 0 0 10 10 10 8 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR65365.1 - 4.3e-29 100.6 30.1 1.5e-23 82.8 0.8 5.7 4 1 3 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EMR65365.1 - 1.3e-25 87.4 18.7 0.0012 18.8 0.0 10.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 EMR65365.1 - 2.2e-20 72.9 22.7 2.6e-08 34.3 4.7 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMR65365.1 - 3e-19 68.0 15.5 0.0082 16.9 0.2 9.9 5 1 4 10 10 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EMR65365.1 - 2.2e-18 65.2 12.6 0.0068 16.7 0.0 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 EMR65365.1 - 1.9e-17 63.3 25.1 0.087 13.1 0.0 9.1 6 3 1 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EMR65365.1 - 2e-17 62.6 21.2 2.5e-07 30.3 1.4 8.7 7 4 4 11 11 11 4 TPR repeat TPR_16 PF13432.6 EMR65365.1 - 3.3e-16 59.6 30.4 4.4e-07 30.5 0.2 7.8 7 2 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMR65365.1 - 7.5e-16 56.9 12.2 0.0039 17.1 0.0 8.7 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EMR65365.1 - 2.9e-11 43.2 15.4 1 10.1 0.0 10.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMR65365.1 - 8.7e-07 29.0 13.2 0.023 14.9 1.0 6.0 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 EMR65365.1 - 6.8e-06 25.5 13.8 0.012 14.8 2.3 5.2 3 1 1 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.9 EMR65365.1 - 0.0037 17.0 6.1 2.4 7.8 1.1 3.7 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) SRP68 PF16969.5 EMR65365.1 - 0.026 13.6 6.6 0.18 10.8 0.9 2.4 2 0 0 2 2 2 0 RNA-binding signal recognition particle 68 Fis1_TPR_C PF14853.6 EMR65365.1 - 0.041 14.0 4.4 0.1 12.7 0.3 3.5 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 EMR65365.1 - 0.2 12.3 6.6 8.8 7.3 0.4 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5113 PF17140.4 EMR65365.1 - 1.9 8.3 5.1 1.8 8.4 2.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5113) CENP-T_C PF15511.6 EMR65366.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EMR65366.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EMR65366.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EMR65366.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EMR65366.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EMR65366.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EMR65366.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EMR65366.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EMR65366.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region DUF3439 PF11921.8 EMR65367.1 - 3.7 7.5 13.6 0.066 13.2 6.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FAD_binding_6 PF00970.24 EMR65368.1 - 7.8e-30 103.2 0.0 1.2e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EMR65368.1 - 4e-28 98.2 0.0 6.4e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMR65368.1 - 0.00015 21.9 0.0 0.009 16.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Cep57_CLD PF14073.6 EMR65369.1 - 0.017 15.2 8.4 0.031 14.3 8.4 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Gp-FAR-1 PF05823.12 EMR65369.1 - 0.078 13.3 2.0 0.6 10.5 0.5 2.4 1 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2959 PF11172.8 EMR65369.1 - 9.8 6.3 8.0 14 5.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Exonuc_VII_L PF02601.15 EMR65369.1 - 9.8 5.6 9.4 16 4.9 9.3 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Sedlin_N PF04628.13 EMR65370.1 - 3.1e-43 147.0 0.0 3.6e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EMR65370.1 - 0.00061 19.7 0.0 0.0098 15.8 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family Caskin1-CID PF16600.5 EMR65370.1 - 0.53 10.9 6.9 1.2 9.8 6.9 1.6 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain Glyco_hydro_64 PF16483.5 EMR65371.1 - 5e-136 453.8 0.0 5.6e-136 453.6 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Isy1 PF06246.12 EMR65372.1 - 1.8e-91 306.3 2.0 2e-91 306.1 2.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 EMR65372.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 YolD-like protein 5_nucleotid_C PF02872.18 EMR65373.1 - 0.052 13.8 0.0 0.2 11.8 0.0 1.9 1 1 1 2 2 2 0 5'-nucleotidase, C-terminal domain MFS_1 PF07690.16 EMR65374.1 - 3.4e-20 72.3 54.9 9.3e-10 37.9 31.4 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 EMR65374.1 - 4e-08 32.2 23.0 5.2e-08 31.8 23.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Amidase PF01425.21 EMR65375.1 - 2e-86 290.7 0.0 2.8e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Amidase Big_3_5 PF16640.5 EMR65375.1 - 0.018 15.2 1.7 0.034 14.3 1.7 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Beach PF02138.18 EMR65376.1 - 3.9e-94 315.1 0.0 5.6e-94 314.6 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EMR65376.1 - 9.2e-07 29.5 6.2 0.022 15.6 0.2 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EMR65377.1 - 4.8e-09 35.7 8.9 4.8e-09 35.7 8.9 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EMR65377.1 - 0.0097 16.2 7.2 0.024 14.9 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EMR65377.1 - 1.2 9.4 10.1 3.6 8.0 8.2 2.3 1 1 1 2 2 2 0 RING-H2 zinc finger domain C1_1 PF00130.22 EMR65377.1 - 2 8.4 8.6 8.2 6.4 8.6 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UQ_con PF00179.26 EMR65379.1 - 1.2e-46 157.9 0.0 1.3e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMR65379.1 - 0.0025 17.5 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMR65379.1 - 0.063 13.6 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain PRP38 PF03371.15 EMR65380.1 - 5.4e-56 189.2 0.0 6.6e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 PRP38 family CDC45 PF02724.14 EMR65380.1 - 5.4 5.2 15.2 6 5.0 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S8 PF00082.22 EMR65381.1 - 2.8e-31 108.9 5.8 4.9e-31 108.1 5.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR65381.1 - 9e-22 77.5 0.2 2.3e-21 76.3 0.2 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Phasin PF05597.11 EMR65381.1 - 0.032 14.3 0.6 0.062 13.3 0.6 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NmrA PF05368.13 EMR65382.1 - 5.9e-37 127.5 0.2 1e-36 126.7 0.1 1.4 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EMR65382.1 - 1.8e-13 50.8 0.3 3.1e-13 50.0 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR65382.1 - 7.1e-09 35.5 0.1 2.2e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR65382.1 - 0.0073 16.2 0.3 0.012 15.5 0.3 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EMR65382.1 - 0.024 13.6 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMR65382.1 - 0.026 13.9 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EMR65382.1 - 0.12 12.9 0.5 0.3 11.7 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SIP1 PF04938.12 EMR65383.1 - 6.3e-10 39.1 0.1 6.7e-07 29.2 0.1 3.2 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Sigma70_ner PF04546.13 EMR65383.1 - 7.2 6.4 13.8 0.2 11.5 2.6 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Pyridoxal_deC PF00282.19 EMR65384.1 - 2.5e-62 210.8 0.0 3.4e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EMR65384.1 - 0.00055 19.0 0.0 0.0012 17.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.32 EMR65385.1 - 1e-09 38.8 16.6 0.0048 17.7 0.3 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat RWD PF05773.22 EMR65385.1 - 0.00049 20.4 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain ADH_zinc_N PF00107.26 EMR65386.1 - 1.9e-16 60.2 0.1 3.4e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR65386.1 - 0.0049 17.9 0.0 0.0093 17.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Smr PF01713.21 EMR65386.1 - 0.032 14.6 0.2 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Smr domain DDOST_48kD PF03345.14 EMR65387.1 - 1.2e-167 558.0 0.0 1.4e-167 557.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta WD40 PF00400.32 EMR65388.1 - 1.1e-10 41.9 1.3 0.35 11.8 0.0 6.6 5 1 1 6 6 6 3 WD domain, G-beta repeat CDC45 PF02724.14 EMR65388.1 - 0.65 8.2 17.0 1.5 7.0 15.4 1.9 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 EMR65388.1 - 1.1 7.3 20.4 1.4 7.0 20.4 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 EMR65388.1 - 3.7 6.7 4.4 5.2 6.2 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_127 PF07944.12 EMR65389.1 - 0.0011 17.6 0.1 0.0011 17.5 0.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 MdoG PF04349.12 EMR65389.1 - 0.056 12.4 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG CBM_11 PF03425.13 EMR65389.1 - 0.1 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) zf-Sec23_Sec24 PF04810.15 EMR65389.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Oxidored_FMN PF00724.20 EMR65390.1 - 1.8e-98 329.9 0.0 2.1e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ank_2 PF12796.7 EMR65391.1 - 1.7e-41 140.6 7.8 1.6e-10 41.5 0.0 5.8 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR65391.1 - 2.2e-32 111.0 16.4 2.9e-06 27.7 0.1 9.5 2 2 10 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR65391.1 - 1.7e-29 98.6 9.9 0.003 17.9 0.0 10.7 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 EMR65391.1 - 3e-25 87.9 7.1 5.9e-07 29.6 0.2 8.2 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EMR65391.1 - 2.9e-19 68.6 23.6 0.077 13.5 0.6 10.6 10 1 0 10 10 10 7 Ankyrin repeat zf-C2H2 PF00096.26 EMR65392.1 - 0.0015 18.9 13.9 0.014 15.8 0.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR65392.1 - 0.0059 17.4 9.7 0.64 11.0 0.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Tombus_P33 PF08500.10 EMR65392.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Tombusvirus p33 Acyl_transf_3 PF01757.22 EMR65393.1 - 2e-27 96.1 26.4 2.6e-27 95.8 26.4 1.1 1 0 0 1 1 1 1 Acyltransferase family Stealth_CR2 PF11380.8 EMR65394.1 - 3.4e-18 65.8 0.1 2.1e-17 63.2 0.1 2.2 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 EMR65394.1 - 2.8e-10 39.7 0.0 6.8e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 EMR65394.1 - 1.5e-05 24.8 0.0 4e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 EF-hand_1 PF00036.32 EMR65394.1 - 0.057 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 EF hand Glyco_transf_54 PF04666.13 EMR65395.1 - 6e-10 38.5 0.0 1.1e-08 34.3 0.0 2.4 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region zf-RING_2 PF13639.6 EMR65396.1 - 2.7e-09 37.2 5.6 2.7e-09 37.2 5.6 2.2 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.6 EMR65396.1 - 1.1e-07 31.7 6.7 3.6e-05 23.6 1.7 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 EMR65396.1 - 1.3e-05 25.2 2.0 1.3e-05 25.2 2.0 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EMR65396.1 - 0.00012 22.1 3.0 0.00034 20.6 3.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMR65396.1 - 0.00027 20.8 5.8 0.00027 20.8 5.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.8 EMR65396.1 - 0.00037 20.6 3.6 0.00037 20.6 3.6 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.29 EMR65396.1 - 0.0009 19.1 6.6 0.002 18.0 6.6 1.6 1 0 0 1 1 1 1 PHD-finger SWIM PF04434.17 EMR65396.1 - 0.0015 18.2 1.2 0.0029 17.3 1.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.7 EMR65396.1 - 0.0032 17.7 4.8 0.0032 17.7 4.8 2.3 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EMR65396.1 - 0.021 14.7 6.0 0.021 14.7 6.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EMR65396.1 - 0.026 14.7 4.0 0.064 13.4 4.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger Zf_RING PF16744.5 EMR65396.1 - 0.029 14.5 2.0 0.067 13.3 2.0 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Ndc1_Nup PF09531.10 EMR65396.1 - 0.051 12.3 4.0 0.054 12.2 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RINGv PF12906.7 EMR65396.1 - 0.11 12.6 5.6 0.31 11.2 5.6 1.8 1 0 0 1 1 1 0 RING-variant domain SR-25 PF10500.9 EMR65396.1 - 0.41 10.2 24.3 0.071 12.7 19.9 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-RING_4 PF14570.6 EMR65396.1 - 0.72 9.7 12.2 0.13 12.1 8.0 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Apt1 PF10351.9 EMR65396.1 - 1.7 7.4 6.6 2.7 6.7 6.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ferritin_2 PF13668.6 EMR65397.1 - 8.7e-15 55.1 0.0 1.3e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain TctB PF07331.11 EMR65398.1 - 0.0056 17.0 0.9 0.0069 16.7 0.9 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Polysacc_synt_C PF14667.6 EMR65398.1 - 0.0075 16.3 2.0 0.0098 16.0 2.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain GFO_IDH_MocA PF01408.22 EMR65400.1 - 6.1e-26 91.6 0.1 9.1e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMR65400.1 - 1.6e-12 47.4 0.0 2.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding_2 PF13380.6 EMR65400.1 - 0.01 16.4 0.1 0.017 15.6 0.1 1.4 1 0 0 1 1 1 1 CoA binding domain Semialdhyde_dh PF01118.24 EMR65400.1 - 0.031 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain G6PD_N PF00479.22 EMR65400.1 - 0.046 14.4 0.0 0.075 13.7 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Shikimate_dh_N PF08501.11 EMR65401.1 - 1.5e-21 76.4 0.0 2.4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EMR65401.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain DHquinase_I PF01487.15 EMR65402.1 - 2.7e-23 83.4 0.0 5.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 EMR65402.1 - 2.5e-20 72.5 0.0 7.1e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EMR65402.1 - 4.5e-10 39.1 0.1 9.9e-10 38.0 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EMR65402.1 - 2.1e-07 31.1 0.0 4.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SKI PF01202.22 EMR65402.1 - 9.9e-05 22.5 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase F420_oxidored PF03807.17 EMR65402.1 - 0.0032 18.0 0.0 0.0081 16.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EMR65402.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DHquinase_II PF01220.19 EMR65403.1 - 2.5e-62 208.6 0.1 2.9e-62 208.4 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Peroxidase_2 PF01328.17 EMR65404.1 - 5.6e-52 177.0 0.0 7.9e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 AP_endonuc_2 PF01261.24 EMR65405.1 - 3.3e-32 111.6 0.0 5e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.24 EMR65406.1 - 6.7e-135 450.4 21.2 7.7e-135 450.2 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR65406.1 - 6.5e-26 91.1 26.9 6.5e-26 91.1 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 EMR65407.1 - 2.1e-13 50.2 0.0 2.4e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65407.1 - 3.9e-07 29.9 0.0 5e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR65407.1 - 0.024 14.5 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 KR domain Pyr_redox PF00070.27 EMR65407.1 - 0.13 12.8 0.1 0.26 11.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_43 PF04616.14 EMR65408.1 - 2.3e-28 99.3 5.9 3.2e-28 98.9 5.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EMR65408.1 - 2.6e-24 86.1 0.1 4.7e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5361 PF17318.2 EMR65409.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5361) Lactamase_B PF00753.27 EMR65411.1 - 1.1e-08 35.3 4.0 6.1e-08 32.9 4.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMR65411.1 - 0.0023 17.5 0.1 0.048 13.2 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain AMP-binding PF00501.28 EMR65412.1 - 2.7e-87 293.1 0.0 3.6e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR65412.1 - 1.3e-14 54.9 1.4 5.3e-14 53.0 1.0 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain FoP_duplication PF13865.6 EMR65413.1 - 0.014 15.9 0.8 0.014 15.9 0.8 2.9 3 1 1 4 4 4 0 C-terminal duplication domain of Friend of PRMT1 AP_endonuc_2 PF01261.24 EMR65413.1 - 0.027 13.9 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ACC_epsilon PF13822.6 EMR65413.1 - 0.068 13.9 0.8 0.068 13.9 0.8 3.2 3 1 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit DUF2339 PF10101.9 EMR65413.1 - 0.09 11.3 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TPR_20 PF14561.6 EMR65413.1 - 0.11 12.9 2.1 6.2 7.2 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMR65413.1 - 2.5 8.8 9.2 4.6 8.0 2.8 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Atg29_N PF18388.1 EMR65414.1 - 1.4e-27 95.2 2.0 2.3e-27 94.5 2.0 1.3 1 0 0 1 1 1 1 Atg29 N-terminal domain Cwf_Cwc_15 PF04889.12 EMR65414.1 - 0.11 12.2 0.4 0.13 11.9 0.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Uso1_p115_C PF04871.13 EMR65414.1 - 0.13 12.6 0.8 0.34 11.3 0.2 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3246 PF11596.8 EMR65414.1 - 0.35 10.3 4.5 0.55 9.6 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Prok-E2_D PF14460.6 EMR65415.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family D 2OG-FeII_Oxy_2 PF13532.6 EMR65416.1 - 2.6e-21 76.7 0.0 4.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4191 PF13829.6 EMR65418.1 - 0.3 10.4 4.8 0.058 12.7 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Ribosomal_S14 PF00253.21 EMR65419.1 - 8.9e-21 73.4 0.5 8.9e-21 73.4 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e RRM_1 PF00076.22 EMR65419.1 - 0.03 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amino_oxidase PF01593.24 EMR65421.1 - 2e-39 136.1 0.1 6.3e-39 134.5 0.0 1.8 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR65421.1 - 9.8e-06 25.7 0.0 2.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain RAI16-like PF10257.9 EMR65421.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein MIP PF00230.20 EMR65422.1 - 2.3e-41 142.0 5.2 2.9e-41 141.6 5.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein ThrE PF06738.12 EMR65422.1 - 0.31 10.4 5.2 0.62 9.4 4.8 1.7 1 1 0 1 1 1 0 Putative threonine/serine exporter 3Beta_HSD PF01073.19 EMR65423.1 - 9.8e-17 60.9 0.0 1.4e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMR65423.1 - 7.8e-13 48.4 0.0 1.9e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR65423.1 - 2.7e-09 37.2 0.0 4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMR65423.1 - 4e-08 32.7 0.0 1.4e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EMR65423.1 - 3.5e-07 30.0 0.0 1.3e-06 28.1 0.0 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMR65423.1 - 2e-06 27.4 0.0 5.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EMR65423.1 - 0.00024 20.8 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMR65423.1 - 0.00082 18.6 0.0 0.002 17.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EMR65423.1 - 0.0072 16.2 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 KR domain RRM_1 PF00076.22 EMR65424.1 - 2.8e-82 270.5 3.7 2.3e-20 72.2 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EMR65424.1 - 1.4e-28 98.8 1.1 7.5e-28 96.5 1.2 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EMR65424.1 - 6e-08 32.3 0.0 0.0036 16.9 0.0 4.5 3 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR65424.1 - 0.00016 21.7 0.3 1.5 9.0 0.0 5.1 4 1 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 EMR65424.1 - 0.00024 20.9 0.0 3.1 7.7 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EMR65424.1 - 0.00055 19.9 0.7 2.2 8.3 0.1 4.5 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 EMR65424.1 - 0.011 16.2 6.3 0.38 11.3 0.3 3.3 3 0 0 3 3 3 0 Heat induced stress protein YflT OB_RNB PF08206.11 EMR65424.1 - 0.15 11.7 2.4 13 5.6 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain DHHA1 PF02272.19 EMR65424.1 - 1.2 9.5 4.1 2.2 8.7 0.1 2.8 3 0 0 3 3 3 0 DHHA1 domain FNIP_N PF14636.6 EMR65424.1 - 1.8 9.5 6.8 0.33 11.9 1.0 2.4 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus p450 PF00067.22 EMR65425.1 - 1.2e-31 110.0 0.0 1.9e-27 96.2 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 AP3D1 PF06375.11 EMR65425.1 - 0.12 12.7 5.6 0.18 12.0 5.6 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4710 PF15828.5 EMR65425.1 - 7.9 6.7 10.5 22 5.2 10.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) XFP_N PF09364.10 EMR65426.1 - 0.074 11.8 0.0 0.31 9.8 0.0 1.8 2 0 0 2 2 2 0 XFP N-terminal domain Baculo_PEP_C PF04513.12 EMR65426.1 - 0.17 11.9 0.0 0.66 10.0 0.0 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Usp PF00582.26 EMR65427.1 - 8.1e-16 58.8 0.6 4.3e-15 56.5 0.0 2.4 2 1 0 2 2 2 1 Universal stress protein family HECT PF00632.25 EMR65428.1 - 5.5e-80 269.1 0.0 7e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TauD PF02668.16 EMR65428.1 - 0.022 14.5 0.0 0.091 12.5 0.0 1.9 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Mucin PF01456.17 EMR65429.1 - 1.1 9.2 25.5 0.24 11.4 21.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein HisKA_4TM PF16926.5 EMR65430.1 - 5.3 6.6 6.8 0.77 9.3 0.8 2.0 1 1 1 2 2 2 0 Archaeal 4TM region of histidine kinase TrkH PF02386.16 EMR65431.1 - 3.4e-92 309.5 0.0 4.3e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 Cation transport protein F-box-like PF12937.7 EMR65432.1 - 0.0044 16.9 0.3 0.012 15.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like LPMO_10 PF03067.15 EMR65433.1 - 0.00027 21.6 0.0 0.00036 21.3 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Keratin_2_head PF16208.5 EMR65434.1 - 0.078 13.1 20.7 0.074 13.2 15.2 2.3 2 0 0 2 2 2 0 Keratin type II head Dus PF01207.17 EMR65435.1 - 1.1e-35 123.2 0.0 8.8e-27 94.0 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 EMR65435.1 - 0.15 12.2 9.2 1.3 9.1 1.3 2.7 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 EMR65435.1 - 0.8 9.7 8.6 2.2 8.3 0.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EMR65435.1 - 9.8 6.1 10.4 2.1 8.3 1.2 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger zf-met2 PF12907.7 EMR65436.1 - 0.00067 19.8 1.7 0.0014 18.7 1.7 1.6 1 0 0 1 1 1 1 Zinc-binding DUF1479 PF07350.12 EMR65437.1 - 5.4e-145 483.3 0.0 2e-143 478.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 EMR65437.1 - 0.016 15.4 2.0 0.71 10.1 0.1 3.0 4 0 0 4 4 4 0 Phytanoyl-CoA dioxygenase (PhyH) HHH PF00633.23 EMR65437.1 - 0.029 14.2 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Kelch_4 PF13418.6 EMR65438.1 - 3.6e-25 87.7 7.4 9e-06 25.6 0.0 4.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EMR65438.1 - 1e-20 73.1 1.2 6.1e-05 22.5 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EMR65438.1 - 3.4e-20 71.6 4.1 0.00047 20.3 0.2 4.6 1 1 3 4 4 4 4 Kelch motif Kelch_5 PF13854.6 EMR65438.1 - 2.1e-19 69.1 4.2 6.1e-06 26.1 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EMR65438.1 - 1.8e-18 65.7 3.8 4.6e-05 23.2 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 EMR65438.1 - 4.9e-17 61.8 2.2 7.1e-07 29.4 0.0 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain BTB PF00651.31 EMR65438.1 - 1.5e-09 38.1 0.1 2.6e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 EMR65438.1 - 0.0061 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Tannase PF07519.11 EMR65439.1 - 2.5e-69 234.4 0.0 3e-67 227.6 0.0 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EMR65439.1 - 0.00037 20.0 0.1 0.41 10.1 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EMR65439.1 - 0.018 14.7 0.0 0.05 13.2 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR65439.1 - 0.063 12.5 0.0 0.59 9.3 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Kelch_5 PF13854.6 EMR65440.1 - 7.1e-40 134.4 11.2 2.8e-07 30.4 0.0 6.9 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EMR65440.1 - 8.5e-37 124.5 17.1 3.9e-10 39.2 0.8 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EMR65440.1 - 7.5e-35 118.7 16.1 2.1e-08 34.0 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EMR65440.1 - 3.3e-34 116.0 10.9 9.6e-08 32.0 0.1 6.6 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EMR65440.1 - 2.4e-30 103.3 13.1 1.7e-08 34.1 0.2 6.9 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EMR65440.1 - 1.7e-19 69.6 47.4 3.6e-07 30.3 0.1 9.0 9 1 0 9 9 9 5 Galactose oxidase, central domain ADH_N PF08240.12 EMR65441.1 - 1.9e-26 92.1 4.2 1.9e-26 92.1 4.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR65441.1 - 2.2e-15 56.8 0.0 3.5e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR65441.1 - 1.5e-06 27.9 0.5 0.0004 19.9 0.2 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus DIOX_N PF14226.6 EMR65442.1 - 3.6e-32 111.6 0.0 1.9e-31 109.2 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR65442.1 - 7.5e-14 52.1 0.0 2e-13 50.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ANAPC4_WD40 PF12894.7 EMR65443.1 - 4.2e-17 62.2 5.4 2.8e-05 24.3 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMR65443.1 - 3.1e-15 56.3 18.6 0.00033 21.4 0.1 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EMR65443.1 - 6.3e-06 25.4 0.1 0.00034 19.7 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EMR65443.1 - 1.8e-05 24.7 0.5 0.0008 19.3 0.1 2.5 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A HIG_1_N PF04588.13 EMR65444.1 - 1.5e-06 28.3 0.4 1.5e-06 28.3 0.4 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF981 PF06168.11 EMR65444.1 - 0.07 13.0 0.1 0.73 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF981) Romo1 PF10247.9 EMR65444.1 - 0.12 12.7 5.4 0.21 12.0 5.4 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Bap31 PF05529.12 EMR65445.1 - 2.3e-45 153.8 8.9 3e-45 153.4 8.9 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EMR65445.1 - 4e-13 49.1 4.2 4e-13 49.1 4.2 1.9 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 EMR65445.1 - 0.0084 15.7 0.9 0.012 15.2 0.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein V_ATPase_I PF01496.19 EMR65445.1 - 0.062 11.2 0.3 0.11 10.4 0.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF722 PF05263.11 EMR65445.1 - 0.065 13.4 0.6 0.12 12.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF722) DUF4337 PF14235.6 EMR65445.1 - 0.3 11.2 2.2 0.62 10.2 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) She9_MDM33 PF05546.11 EMR65445.1 - 2.3 8.0 6.3 0.13 12.1 0.7 1.7 2 0 0 2 2 2 0 She9 / Mdm33 family ESM4 PF15952.5 EMR65447.1 - 7.6 6.9 7.0 48 4.3 7.0 2.1 1 1 0 1 1 1 0 Enhancer of split M4 family ATG2_CAD PF13329.6 EMR65449.1 - 1.8e-53 180.4 0.5 3.9e-53 179.3 0.3 1.7 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EMR65449.1 - 6.9e-32 109.7 0.7 7.3e-31 106.4 0.1 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EMR65449.1 - 0.0025 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Glyco_hydro_43 PF04616.14 EMR65451.1 - 1.5e-68 231.2 0.7 2e-68 230.8 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EMR65451.1 - 8.3e-10 38.7 0.0 2.4e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5005 PF16396.5 EMR65451.1 - 0.08 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) Chorein_N PF12624.7 EMR65452.1 - 3.7e-05 23.8 1.0 0.00012 22.2 0.1 2.2 2 1 0 2 2 2 1 N-terminal region of Chorein or VPS13 SKA2 PF16740.5 EMR65453.1 - 0.00014 21.6 0.6 0.00024 20.9 0.6 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 HIP1_clath_bdg PF16515.5 EMR65453.1 - 0.0043 17.6 1.6 0.0085 16.7 1.6 1.4 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C2H2 PF00096.26 EMR65453.1 - 0.015 15.7 14.6 1 10.0 2.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EMR65453.1 - 0.018 15.2 0.2 0.09 12.9 0.0 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger GAS PF13851.6 EMR65453.1 - 0.018 14.4 1.4 0.031 13.6 1.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EMR65453.1 - 0.039 14.4 3.2 0.079 13.4 3.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Rootletin PF15035.6 EMR65453.1 - 0.05 13.6 2.5 0.1 12.6 2.5 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF812 PF05667.11 EMR65453.1 - 0.058 12.3 0.2 0.077 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Macoilin PF09726.9 EMR65453.1 - 0.078 11.5 1.2 0.13 10.8 1.2 1.2 1 0 0 1 1 1 0 Macoilin family CLZ PF16526.5 EMR65453.1 - 0.1 13.0 1.7 0.23 11.8 1.7 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CDC73_N PF16050.5 EMR65453.1 - 0.17 11.2 1.1 0.29 10.4 1.1 1.3 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal DUF4407 PF14362.6 EMR65453.1 - 0.17 11.2 1.7 0.2 11.0 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.18 EMR65453.1 - 0.21 11.8 1.1 0.29 11.4 0.0 1.8 2 0 0 2 2 1 0 Homeobox associated leucine zipper CENP-H PF05837.12 EMR65453.1 - 0.26 11.7 2.4 0.46 10.9 2.4 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-C2H2_4 PF13894.6 EMR65453.1 - 6.4 7.9 12.6 23 6.2 0.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.32 EMR65455.1 - 3.5e-16 59.3 27.8 1.8e-06 28.6 0.7 6.5 7 1 1 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR65455.1 - 2.3e-08 34.2 0.2 0.0065 16.7 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR65455.1 - 0.00063 18.5 0.0 3.7 6.1 0.0 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Fungal_TACC PF12709.7 EMR65456.1 - 2.6e-10 40.6 1.0 2.6e-10 40.6 1.0 5.0 5 0 0 5 5 5 2 Fungal Transforming acidic coiled-coil (TACC) proteins MAP65_ASE1 PF03999.12 EMR65456.1 - 0.00029 19.7 12.8 0.00029 19.7 12.8 4.2 4 1 0 4 4 4 1 Microtubule associated protein (MAP65/ASE1 family) zf-C4H2 PF10146.9 EMR65456.1 - 0.0014 19.0 10.2 0.0014 19.0 10.2 3.9 3 1 0 3 3 3 2 Zinc finger-containing protein DUF1179 PF06678.11 EMR65456.1 - 1.4 8.9 6.4 1.7 8.6 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Spt20 PF12090.8 EMR65456.1 - 2.1 7.9 39.8 0.43 10.2 24.0 2.6 2 0 0 2 2 2 0 Spt20 family DUF4407 PF14362.6 EMR65456.1 - 2.3 7.5 33.5 2.3 7.5 5.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Activator_LAG-3 PF11498.8 EMR65456.1 - 2.7 6.9 33.2 0.01 14.8 23.0 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 XhlA PF10779.9 EMR65456.1 - 4.4 7.6 8.7 13 6.0 1.2 3.4 3 0 0 3 3 3 0 Haemolysin XhlA TMEM51 PF15345.6 EMR65456.1 - 7.8 6.3 19.4 6.5 6.5 1.3 2.6 2 0 0 2 2 2 0 Transmembrane protein 51 Acyl-CoA_dh_1 PF00441.24 EMR65457.1 - 3.8e-35 121.3 0.3 6.1e-35 120.6 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EMR65457.1 - 4.6e-19 68.3 0.0 1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EMR65457.1 - 7e-17 61.4 0.1 1.5e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMR65457.1 - 2.9e-08 34.4 0.3 1.6e-07 32.0 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMR65457.1 - 0.00015 22.0 0.0 0.00044 20.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_S20p PF01649.18 EMR65457.1 - 0.041 14.5 0.0 0.083 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 AA_permease PF00324.21 EMR65458.1 - 2.9e-102 342.7 46.7 4.7e-101 338.7 46.7 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR65458.1 - 2.4e-25 89.2 43.2 3.1e-25 88.9 43.2 1.1 1 0 0 1 1 1 1 Amino acid permease Cellulase PF00150.18 EMR65458.1 - 3.5e-17 62.8 0.0 8.3e-12 45.1 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EMR65458.1 - 0.00012 22.6 0.0 0.00026 21.5 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 EMR65458.1 - 0.0018 18.0 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Peroxidase_2 PF01328.17 EMR65459.1 - 5.5e-42 144.4 0.0 7.1e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PS_Dcarbxylase PF02666.15 EMR65460.1 - 3e-55 186.9 0.0 4.7e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EMR65460.1 - 9e-37 125.5 0.0 7.5e-17 61.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain eIF3_subunit PF08597.10 EMR65460.1 - 0.0012 18.8 0.7 0.42 10.5 0.5 2.6 2 0 0 2 2 2 2 Translation initiation factor eIF3 subunit PGA2 PF07543.12 EMR65460.1 - 0.013 15.5 3.3 0.24 11.4 0.5 2.9 2 0 0 2 2 2 0 Protein trafficking PGA2 EF-hand_6 PF13405.6 EMR65460.1 - 0.041 13.8 0.6 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EMR65460.1 - 0.057 13.0 0.3 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 EF hand ADIP PF11559.8 EMR65461.1 - 1e-13 51.7 11.9 1.2e-09 38.4 0.4 4.9 4 1 1 5 5 5 2 Afadin- and alpha -actinin-Binding AFG1_ATPase PF03969.16 EMR65462.1 - 7.5e-57 192.9 0.0 1.6e-26 93.1 0.0 5.1 4 1 1 5 5 5 5 AFG1-like ATPase AAA_16 PF13191.6 EMR65462.1 - 1.1e-05 25.9 0.2 0.017 15.5 0.0 3.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EMR65462.1 - 0.0014 18.6 0.0 0.0054 16.7 0.0 2.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 EMR65462.1 - 0.0016 18.4 0.1 0.13 12.2 0.0 2.7 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EMR65462.1 - 0.0081 16.4 0.0 0.031 14.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain SUIM_assoc PF16619.5 EMR65462.1 - 0.024 14.7 3.3 0.057 13.5 3.3 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 AAA_29 PF13555.6 EMR65462.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EMR65462.1 - 0.057 13.9 0.3 9.5 6.7 0.1 2.6 1 1 1 2 2 2 0 ABC transporter AAA PF00004.29 EMR65462.1 - 0.09 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 EMR65462.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF952 PF06108.12 EMR65463.1 - 6e-22 77.5 0.0 8.4e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Pkinase PF00069.25 EMR65464.1 - 2.7e-21 76.1 0.0 6.7e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR65464.1 - 1.3e-10 41.0 0.0 5.9e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase WW PF00397.26 EMR65464.1 - 0.04 14.0 5.3 0.06 13.4 0.1 3.2 4 0 0 4 4 4 0 WW domain Amino_oxidase PF01593.24 EMR65465.1 - 3.2e-13 49.8 2.7 7.2e-06 25.5 2.3 2.7 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EMR65465.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Peptidase_M57 PF12388.8 EMR65466.1 - 0.048 13.3 0.2 0.91 9.1 0.0 2.1 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M64 PF09471.10 EMR65466.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 Amidase02_C PF12123.8 EMR65466.1 - 0.075 12.7 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase MFS_1 PF07690.16 EMR65467.1 - 2.3e-16 59.7 19.2 2.9e-15 56.1 19.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily IDO PF01231.18 EMR65468.1 - 1.3e-31 109.9 0.0 1.7e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase zf-AN1 PF01428.16 EMR65469.1 - 1.1e-12 47.9 4.6 1.1e-12 47.9 4.6 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Stomagen PF16851.5 EMR65469.1 - 0.12 12.5 0.7 0.12 12.5 0.7 2.0 2 1 0 2 2 2 0 Stomagen p450 PF00067.22 EMR65470.1 - 6.7e-66 222.9 0.0 8.5e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.17 EMR65470.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Reticulon CP_ATPgrasp_2 PF14403.6 EMR65471.1 - 1.2e-113 379.8 0.0 1.8e-113 379.3 0.0 1.3 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 EMR65471.1 - 1.1e-81 274.5 0.0 1.5e-81 274.0 0.0 1.2 1 0 0 1 1 1 1 A circularly permuted ATPgrasp GCS2 PF04107.13 EMR65471.1 - 9.9e-43 146.5 0.2 1.5e-42 145.9 0.2 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) ATPgrasp_YheCD PF14398.6 EMR65471.1 - 0.0086 15.4 0.0 0.11 11.8 0.0 2.1 1 1 0 1 1 1 1 YheC/D like ATP-grasp Coatomer_E PF04733.14 EMR65472.1 - 5e-59 200.1 5.1 5.8e-59 199.9 5.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EMR65472.1 - 1.7e-09 38.0 19.2 0.00018 22.0 2.4 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR65472.1 - 2e-07 31.1 0.1 0.62 10.3 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EMR65472.1 - 3.7e-05 24.2 16.9 0.0051 17.5 0.2 6.2 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMR65472.1 - 4.3e-05 23.9 6.3 0.11 13.2 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMR65472.1 - 0.00011 22.2 0.9 2.9 8.3 0.0 5.0 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR65472.1 - 0.00012 21.7 0.6 1.5 8.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMR65472.1 - 0.00042 20.5 11.7 0.92 9.8 0.2 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMR65472.1 - 0.0016 19.1 11.7 0.24 12.1 0.0 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_5 PF12688.7 EMR65472.1 - 0.0034 17.6 4.1 0.76 10.0 0.3 2.8 2 1 1 3 3 3 2 Tetratrico peptide repeat Type_III_YscG PF09477.10 EMR65472.1 - 0.0066 16.5 1.8 0.055 13.5 0.1 3.0 1 1 0 2 2 2 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_2 PF07719.17 EMR65472.1 - 0.0092 16.0 13.4 0.023 14.8 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMR65472.1 - 0.015 15.0 7.6 0.052 13.2 0.4 4.5 6 0 0 6 6 6 0 TPR repeat NARP1 PF12569.8 EMR65472.1 - 0.021 13.7 1.1 3.1 6.6 0.2 2.3 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 Arg_tRNA_synt_N PF03485.16 EMR65472.1 - 0.083 13.5 0.2 0.18 12.4 0.2 1.6 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain TPR_17 PF13431.6 EMR65472.1 - 0.084 13.3 1.2 18 6.0 0.0 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EMR65472.1 - 2.1 8.6 7.3 1.5 9.0 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR65472.1 - 2.7 8.9 0.0 2.7 8.9 0.0 6.1 8 0 0 8 8 5 0 Tetratricopeptide repeat Fungal_trans PF04082.18 EMR65473.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain HAD PF12710.7 EMR65475.1 - 3.8e-22 79.6 0.1 5.4e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EMR65475.1 - 0.0053 16.2 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.12 EMR65475.1 - 0.022 14.3 0.1 0.074 12.5 0.0 2.0 3 0 0 3 3 3 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EMR65475.1 - 0.032 14.5 0.2 0.15 12.3 0.2 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Radical_SAM PF04055.21 EMR65475.1 - 0.1 13.0 0.0 5.2 7.4 0.0 2.5 1 1 0 1 1 1 0 Radical SAM superfamily Cut8 PF08559.10 EMR65476.1 - 6.9e-79 264.9 0.0 8.4e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Nucleoporin_C PF03177.14 EMR65477.1 - 8.1e-154 513.6 14.7 1.2e-153 513.1 14.7 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EMR65477.1 - 9.9e-81 271.7 0.2 1.3e-80 271.3 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Transcrip_act PF04949.13 EMR65477.1 - 0.00078 19.4 2.9 0.018 14.9 0.1 2.9 3 0 0 3 3 3 2 Transcriptional activator DNA_pol_E_B PF04042.16 EMR65478.1 - 1.8e-56 190.9 0.0 2.8e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CDC45 PF02724.14 EMR65478.1 - 0.042 12.2 3.5 0.067 11.5 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3439 PF11921.8 EMR65478.1 - 1.3 9.0 10.3 3.9 7.4 10.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Laminin_G_3 PF13385.6 EMR65479.1 - 7.2e-06 26.2 0.4 7.2e-06 26.2 0.4 1.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_16 PF00722.21 EMR65479.1 - 0.00086 18.8 0.1 0.0012 18.3 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 CD20 PF04103.15 EMR65481.1 - 0.89 9.6 4.4 0.25 11.4 1.6 1.4 2 0 0 2 2 2 0 CD20-like family E1-E2_ATPase PF00122.20 EMR65482.1 - 8.5e-48 162.3 3.0 8.5e-48 162.3 3.0 2.4 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EMR65482.1 - 6.3e-21 75.6 3.4 6.8e-20 72.3 3.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EMR65482.1 - 1.4e-06 28.6 0.1 4.3e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EMR65482.1 - 4.3e-06 26.6 0.1 0.0089 15.8 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EMR65482.1 - 0.061 12.8 0.0 10 5.6 0.0 2.6 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase DUF3439 PF11921.8 EMR65482.1 - 1.5 8.8 12.0 0.21 11.6 3.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) KAR9 PF08580.10 EMR65483.1 - 5.9e-41 140.8 2.6 7.8e-41 140.4 2.6 1.1 1 0 0 1 1 1 1 Yeast cortical protein KAR9 DEC-1_N PF04625.13 EMR65483.1 - 0.0085 15.1 3.8 0.013 14.6 3.8 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region PLU-1 PF08429.11 EMR65483.1 - 0.021 14.0 0.0 0.041 13.0 0.0 1.3 1 1 0 1 1 1 0 PLU-1-like protein SIS PF01380.22 EMR65484.1 - 1.2e-58 196.6 0.1 1.3e-31 109.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EMR65484.1 - 6e-17 62.1 0.0 1.2e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EMR65484.1 - 3.1e-10 40.0 0.0 1e-09 38.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EMR65484.1 - 0.0026 16.7 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II RecQ_Zn_bind PF16124.5 EMR65485.1 - 2.9e-17 63.1 5.5 6.6e-17 62.0 5.5 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 EMR65485.1 - 1.5e-16 60.7 0.0 5.2e-16 59.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.10 EMR65485.1 - 1.2e-15 57.2 0.6 3.5e-15 55.8 0.1 2.1 2 0 0 2 2 2 1 RQC domain DEAD PF00270.29 EMR65485.1 - 6.4e-06 26.0 0.0 0.00036 20.3 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase HEM4 PF02602.15 EMR65485.1 - 0.0046 16.3 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD HRDC PF00570.23 EMR65485.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 HRDC domain HTH_41 PF14502.6 EMR65486.1 - 0.041 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_16 PF13191.6 EMR65488.1 - 2.1e-14 54.2 0.1 2.8e-13 50.6 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR65488.1 - 1.2e-11 45.1 0.0 6.4e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EMR65488.1 - 1.8e-11 44.6 0.0 4.3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EMR65488.1 - 2.6e-06 27.5 0.0 6.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 EMR65488.1 - 5.7e-06 26.7 0.0 1.6e-05 25.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain TniB PF05621.11 EMR65488.1 - 1.6e-05 24.4 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_30 PF13604.6 EMR65488.1 - 0.0006 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EMR65488.1 - 0.0006 19.0 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 EMR65488.1 - 0.00066 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 EMR65488.1 - 0.00099 19.5 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EMR65488.1 - 0.0036 17.3 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EMR65488.1 - 0.0043 16.3 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase_2 PF01637.18 EMR65488.1 - 0.0044 17.0 0.0 0.021 14.8 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 EMR65488.1 - 0.0049 16.0 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein KAP_NTPase PF07693.14 EMR65488.1 - 0.0093 15.2 0.0 0.022 14.0 0.0 1.5 1 1 0 1 1 1 1 KAP family P-loop domain AAA_11 PF13086.6 EMR65488.1 - 0.024 14.4 0.0 0.065 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMR65488.1 - 0.025 15.1 0.0 0.046 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMR65488.1 - 0.027 14.4 0.0 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 EMR65488.1 - 0.042 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA12 PF10443.9 EMR65488.1 - 0.045 12.5 0.0 0.081 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein Rad17 PF03215.15 EMR65488.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 EMR65488.1 - 0.066 13.2 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMR65488.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TerB_C PF15615.6 EMR65488.1 - 0.075 13.3 1.4 0.15 12.3 0.1 2.0 2 0 0 2 2 2 0 TerB-C domain AAA_28 PF13521.6 EMR65488.1 - 0.091 13.0 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EMR65488.1 - 0.1 11.8 0.0 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_32 PF13654.6 EMR65488.1 - 0.14 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMR65488.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 EMR65488.1 - 0.19 10.5 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Proteasome PF00227.26 EMR65489.1 - 2.7e-25 89.0 0.0 1.1e-24 87.0 0.0 1.8 1 1 0 1 1 1 1 Proteasome subunit Peptidase_C97 PF05903.14 EMR65490.1 - 0.071 12.9 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain DUF3716 PF12511.8 EMR65491.1 - 1.9e-12 47.0 3.3 2.9e-12 46.4 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) AAA PF00004.29 EMR65492.1 - 6.7e-43 146.3 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EMR65492.1 - 4.5e-13 48.9 0.2 3.9e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EMR65492.1 - 4.9e-10 39.0 0.2 1.2e-09 37.8 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EMR65492.1 - 9.4e-08 32.6 0.1 6.7e-05 23.3 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EMR65492.1 - 1.8e-06 28.0 0.1 3.8e-05 23.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMR65492.1 - 3.4e-06 27.3 0.0 9.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EMR65492.1 - 7.2e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR65492.1 - 0.00021 21.6 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EMR65492.1 - 0.0004 19.6 0.0 0.00076 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EMR65492.1 - 0.00059 20.4 0.0 0.0025 18.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EMR65492.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EMR65492.1 - 0.0019 17.4 0.1 0.0043 16.3 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 EMR65492.1 - 0.0035 17.5 0.0 0.01 16.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 EMR65492.1 - 0.0037 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EMR65492.1 - 0.0047 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 EMR65492.1 - 0.0052 16.4 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 EMR65492.1 - 0.0056 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EMR65492.1 - 0.0061 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EMR65492.1 - 0.0077 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EMR65492.1 - 0.0083 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EMR65492.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMR65492.1 - 0.021 14.5 0.0 0.057 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EMR65492.1 - 0.023 14.5 0.4 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EMR65492.1 - 0.033 13.5 0.6 0.13 11.5 0.0 2.3 3 0 0 3 3 3 0 KaiC Thymidylate_kin PF02223.17 EMR65492.1 - 0.034 13.8 0.0 3.8 7.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_30 PF13604.6 EMR65492.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMR65492.1 - 0.055 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EMR65492.1 - 0.062 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 EMR65492.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMR65492.1 - 0.086 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMR65492.1 - 0.097 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 EMR65492.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DHHA1 PF02272.19 EMR65492.1 - 0.14 12.5 1.6 1.4 9.3 0.2 2.8 3 0 0 3 3 3 0 DHHA1 domain AAA_13 PF13166.6 EMR65492.1 - 0.57 8.8 2.4 13 4.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cep57_CLD_2 PF14197.6 EMR65492.1 - 4.5 7.4 6.6 0.59 10.2 1.5 2.2 2 1 0 2 2 1 0 Centrosome localisation domain of PPC89 HCNGP PF07818.13 EMR65493.1 - 6.5e-27 94.0 0.0 1.1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein K_channel_TID PF07941.11 EMR65493.1 - 2.4 8.6 17.3 5.6 7.5 17.3 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain p450 PF00067.22 EMR65494.1 - 1.6e-59 201.9 0.0 2.2e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SIR2 PF02146.17 EMR65495.1 - 7.1e-45 153.1 0.0 1.3e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Lipoxygenase PF00305.19 EMR65495.1 - 3.2e-24 85.4 1.3 1.8e-19 69.7 0.2 3.0 1 1 1 2 2 2 2 Lipoxygenase zf-LYAR PF08790.11 EMR65495.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Abhydrolase_3 PF07859.13 EMR65496.1 - 5e-52 176.8 1.2 7.9e-52 176.2 1.2 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR65496.1 - 3.9e-09 35.9 0.1 1.6e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EMR65496.1 - 0.13 11.8 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.18 EMR65497.1 - 9.9e-11 41.2 0.0 2.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR65497.1 - 2.2e-05 24.5 11.9 3.6e-05 23.8 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.20 EMR65498.1 - 7.6e-31 107.6 0.0 9e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.16 EMR65499.1 - 2.9e-39 135.0 21.6 6.4e-39 133.9 21.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65499.1 - 7.6e-14 51.4 13.4 7.6e-14 51.4 7.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMR65499.1 - 1.7e-08 33.3 0.9 2.6e-08 32.8 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EMR65499.1 - 4.4e-05 22.5 0.0 0.066 12.1 0.0 2.8 1 1 1 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 EMR65499.1 - 0.00013 20.5 0.4 0.00022 19.8 0.4 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 EMR65499.1 - 0.0061 15.2 0.9 0.0061 15.2 0.9 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein DUF4118 PF13493.6 EMR65499.1 - 0.029 14.2 0.1 0.029 14.2 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4118) zf-Di19 PF05605.12 EMR65501.1 - 0.0025 18.1 0.2 0.18 12.1 0.1 2.2 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding SKG6 PF08693.10 EMR65502.1 - 0.00012 21.4 3.2 0.00012 21.4 3.2 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EMR65502.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SPX PF03105.19 EMR65502.1 - 0.79 9.6 5.9 1.1 9.1 5.9 1.3 1 0 0 1 1 1 0 SPX domain Glyco_trans_2_3 PF13632.6 EMR65503.1 - 1.5e-19 70.7 0.6 2.8e-19 69.8 0.6 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Mito_carr PF00153.27 EMR65503.1 - 0.14 12.1 0.0 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial carrier protein HET PF06985.11 EMR65504.1 - 1.9e-12 47.7 2.3 4.5e-10 40.1 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1543 PF07566.12 EMR65504.1 - 0.16 11.7 0.1 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) Aldedh PF00171.22 EMR65505.1 - 3.7e-136 454.3 0.9 4.5e-136 454.0 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YtxC PF08812.11 EMR65505.1 - 0.0049 16.5 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 YtxC-like family adh_short_C2 PF13561.6 EMR65506.1 - 5.2e-50 170.2 0.7 7.8e-50 169.6 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR65506.1 - 4.2e-41 140.5 0.8 5.8e-41 140.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR65506.1 - 1.2e-09 38.3 1.0 2e-09 37.6 1.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR65506.1 - 0.05 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 EMR65507.1 - 8.8e-29 99.6 1.2 1.3e-28 99.0 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR65507.1 - 8.4e-22 77.5 0.8 1.2e-21 77.0 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR65507.1 - 2.2e-10 40.4 0.5 3.5e-10 39.7 0.5 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMR65507.1 - 1.8e-05 25.8 0.3 7e-05 23.9 0.0 2.1 3 0 0 3 3 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR65507.1 - 0.00045 19.6 1.2 0.00072 18.9 1.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EMR65507.1 - 0.0056 16.0 0.9 0.014 14.6 0.9 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.25 EMR65507.1 - 0.0076 15.7 1.8 0.012 15.0 1.8 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 EMR65507.1 - 0.0097 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMR65507.1 - 0.02 14.5 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 EMR65507.1 - 0.021 13.5 0.9 0.031 13.0 0.9 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.21 EMR65507.1 - 0.022 14.8 0.8 0.046 13.8 0.8 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_3 PF13738.6 EMR65507.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR65507.1 - 0.21 12.2 1.3 0.47 11.1 0.6 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Met_10 PF02475.16 EMR65507.1 - 0.28 10.9 1.1 0.99 9.1 0.3 2.0 2 0 0 2 2 2 0 Met-10+ like-protein Mannosidase_ig PF17786.1 EMR65508.1 - 5.7e-15 55.7 0.1 1.6e-14 54.3 0.1 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EMR65508.1 - 2.4e-11 44.3 0.2 7.8e-11 42.6 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EMR65508.1 - 2.7e-05 24.1 0.1 7.1e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 EMR65508.1 - 0.0006 19.5 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Ig_GlcNase PF18368.1 EMR65508.1 - 0.016 15.4 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain HET PF06985.11 EMR65510.1 - 1e-25 90.8 0.2 1.9e-25 89.9 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3136 PF11334.8 EMR65510.1 - 0.044 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Amidohydro_2 PF04909.14 EMR65511.1 - 1.6e-39 136.5 0.1 1.9e-39 136.2 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_4 PF01565.23 EMR65512.1 - 1.2e-19 70.4 0.6 2.1e-19 69.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain CARDB PF07705.11 EMR65512.1 - 0.081 13.2 0.1 22 5.4 0.0 2.4 2 0 0 2 2 2 0 CARDB MFS_1 PF07690.16 EMR65513.1 - 1.3e-39 136.2 26.6 1.9e-39 135.6 26.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR65513.1 - 0.006 15.5 8.7 0.0059 15.5 7.6 1.4 1 1 0 1 1 1 1 MFS_1 like family PgaD PF13994.6 EMR65513.1 - 0.043 13.9 1.0 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 PgaD-like protein DUF5413 PF17434.2 EMR65513.1 - 3.6 7.9 8.7 4.8 7.5 0.1 3.8 2 2 1 3 3 3 0 Family of unknown function (DUF5413) Glyco_transf_90 PF05686.12 EMR65514.1 - 2.2e-05 23.6 0.1 0.00056 18.9 0.2 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 90 Pkinase PF00069.25 EMR65515.1 - 6.8e-64 215.8 0.0 1.6e-63 214.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR65515.1 - 2e-36 125.6 0.0 1.4e-30 106.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EMR65515.1 - 3.7e-08 33.0 0.0 0.00016 21.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 EMR65515.1 - 0.00064 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMR65515.1 - 0.0046 16.0 0.2 0.0065 15.4 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EMR65515.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EMR65515.1 - 0.016 14.6 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMR65515.1 - 0.13 11.0 1.8 0.18 10.5 0.1 1.9 2 0 0 2 2 2 0 Fungal protein kinase AltA1 PF16541.5 EMR65516.1 - 6.2e-11 43.1 0.1 1.5e-10 41.9 0.0 1.6 1 1 1 2 2 2 1 Alternaria alternata allergen 1 Methyltrans_SAM PF10672.9 EMR65516.1 - 0.073 12.2 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase p450 PF00067.22 EMR65517.1 - 4.2e-42 144.5 0.0 6.5e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ras PF00071.22 EMR65517.1 - 2.8e-31 108.3 0.0 4.6e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR65517.1 - 2.6e-19 69.6 0.0 5.6e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR65517.1 - 1.4e-05 24.7 0.0 4.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMR65517.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DEAD PF00270.29 EMR65519.1 - 7.3e-26 91.0 0.1 2.9e-25 89.0 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR65519.1 - 4.1e-25 88.3 0.0 8.6e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR65519.1 - 0.00036 20.6 0.0 0.00077 19.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRK PF00485.18 EMR65520.1 - 1.9e-05 24.5 0.1 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 EMR65520.1 - 0.11 13.0 0.2 0.51 10.9 0.2 1.8 1 1 0 1 1 1 0 ABC transporter DUF87 PF01935.17 EMR65520.1 - 0.23 11.5 0.2 0.38 10.8 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain SPX PF03105.19 EMR65521.1 - 1.2 9.0 10.4 1.4 8.8 10.4 1.2 1 0 0 1 1 1 0 SPX domain RCDG1 PF15725.5 EMR65521.1 - 1.5 9.3 18.0 0.53 10.7 4.1 2.6 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein SHS2_Rpb7-N PF03876.17 EMR65523.1 - 2.6e-15 56.6 0.0 4.6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EMR65523.1 - 8e-12 45.3 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain LAM_C PF12544.8 EMR65524.1 - 5.1e-05 23.5 0.0 9.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 EMR65524.1 - 0.00059 20.2 0.0 0.0012 19.3 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EMR65524.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.6 EMR65524.1 - 0.16 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF962 PF06127.11 EMR65525.1 - 8.1e-09 35.5 0.1 1e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SNF5 PF04855.12 EMR65526.1 - 6.5e-63 212.7 1.9 1e-61 208.8 0.2 2.5 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.24 EMR65527.1 - 3.5e-07 30.1 0.1 5.1e-07 29.6 0.1 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 DUF4258 PF14076.6 EMR65527.1 - 0.091 13.1 0.2 6.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) GDP_Man_Dehyd PF16363.5 EMR65528.1 - 3.4e-69 233.8 0.0 4e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMR65528.1 - 1.1e-56 192.0 0.0 1.4e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR65528.1 - 3.2e-21 75.6 0.0 4.3e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMR65528.1 - 5.6e-21 74.9 0.0 6.3e-20 71.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EMR65528.1 - 8.2e-19 67.8 0.4 1.7e-17 63.4 0.4 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EMR65528.1 - 3.2e-16 59.3 0.0 4.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMR65528.1 - 1.8e-07 31.2 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EMR65528.1 - 0.12 11.8 0.0 4.8 6.6 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase PHD PF00628.29 EMR65529.1 - 2.7e-14 52.8 16.8 2.4e-08 33.7 9.6 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 EMR65529.1 - 0.0012 18.5 6.8 0.015 14.9 1.3 2.4 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 EMR65529.1 - 0.004 17.4 7.9 1.3 9.3 0.1 2.4 2 0 0 2 2 2 2 PHD-like zinc-binding domain DUF3621 PF12285.8 EMR65529.1 - 0.04 14.3 1.8 2.9 8.3 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3621) PHD_2 PF13831.6 EMR65529.1 - 0.077 12.6 8.4 0.38 10.4 4.1 2.7 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 EMR65529.1 - 4.9 7.5 14.8 1.4 9.3 0.4 2.5 2 0 0 2 2 2 0 C1 domain AAA PF00004.29 EMR65531.1 - 1.5e-14 54.5 0.0 2.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMR65531.1 - 0.00058 20.2 1.2 0.018 15.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain Torsin PF06309.11 EMR65531.1 - 0.0012 19.0 0.0 0.0032 17.6 0.0 1.7 1 1 0 1 1 1 1 Torsin AAA_16 PF13191.6 EMR65531.1 - 0.014 15.8 0.1 0.025 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Phage_int_SAM_2 PF12834.7 EMR65531.1 - 0.016 15.9 0.0 0.032 14.9 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal Sigma54_activat PF00158.26 EMR65531.1 - 0.022 14.4 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 EMR65531.1 - 0.023 14.7 0.0 0.058 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) CPT PF07931.12 EMR65531.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 EMR65531.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EMR65531.1 - 0.096 12.4 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EMR65531.1 - 0.15 11.7 0.3 0.52 10.0 0.3 1.9 1 1 0 1 1 1 0 AAA domain Acetyltransf_10 PF13673.7 EMR65532.1 - 5e-14 52.3 0.0 1e-13 51.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR65532.1 - 7.3e-12 45.6 0.0 9.4e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR65532.1 - 3e-10 40.4 0.0 4.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMR65532.1 - 0.00023 21.3 0.0 0.00083 19.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 EMR65532.1 - 0.0092 15.8 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR65532.1 - 0.025 14.6 0.1 0.13 12.4 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Lactamase_B_4 PF13691.6 EMR65532.1 - 0.11 12.3 0.1 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 tRNase Z endonuclease TPM_phosphatase PF04536.14 EMR65532.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 TPM domain Rbx_binding PF18113.1 EMR65532.1 - 0.12 12.1 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain FR47 PF08445.10 EMR65532.1 - 0.16 12.0 0.0 0.54 10.3 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Pep3_Vps18 PF05131.14 EMR65533.1 - 2.7e-48 163.6 0.0 6.5e-48 162.3 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EMR65533.1 - 5.7e-09 36.0 5.5 2.6e-07 30.6 0.0 3.3 3 2 1 4 4 4 1 Region in Clathrin and VPS Methyltransf_23 PF13489.6 EMR65533.1 - 2.8e-05 24.0 0.0 7.8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR65533.1 - 4.5e-05 24.1 0.0 0.00018 22.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR65533.1 - 0.00021 22.0 0.2 0.00099 19.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMR65533.1 - 0.00052 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Zn_ribbon_17 PF17120.5 EMR65533.1 - 0.00072 19.1 0.2 0.0015 18.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Methyltransf_2 PF00891.18 EMR65533.1 - 0.0098 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 EMR65533.1 - 0.018 14.9 0.0 0.084 12.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain zf-rbx1 PF12678.7 EMR65533.1 - 0.018 15.3 0.2 0.044 14.1 0.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EMR65533.1 - 0.02 14.8 0.8 0.046 13.7 0.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain CMAS PF02353.20 EMR65533.1 - 0.022 14.1 0.2 0.047 13.0 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase zf-RING_11 PF17123.5 EMR65533.1 - 0.07 12.9 7.7 0.011 15.4 3.3 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 EMR65533.1 - 0.074 13.4 0.4 0.18 12.2 0.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 EMR65533.1 - 0.18 11.9 0.1 0.45 10.6 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMR65533.1 - 0.29 11.0 0.7 0.7 9.8 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YEATS PF03366.16 EMR65534.1 - 3.9e-11 42.8 0.7 6.4e-11 42.1 0.7 1.3 1 0 0 1 1 1 1 YEATS family Abhydrolase_6 PF12697.7 EMR65536.1 - 4e-13 50.5 5.9 5.9e-13 49.9 5.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR65536.1 - 8.5e-13 48.5 0.5 2.3e-12 47.1 0.7 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR65536.1 - 9.8e-08 31.5 0.3 5.2e-07 29.2 0.2 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EMR65536.1 - 0.00039 20.1 0.0 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_8 PF06259.12 EMR65536.1 - 0.00042 20.0 1.3 0.00066 19.4 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Peptidase_S15 PF02129.18 EMR65536.1 - 0.022 14.4 0.7 0.13 11.9 0.7 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 EMR65536.1 - 0.041 13.6 0.1 0.064 13.0 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 EMR65536.1 - 0.042 13.3 0.1 1.6 8.1 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF676 PF05057.14 EMR65536.1 - 0.058 12.9 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIP PF03583.14 EMR65536.1 - 0.079 12.3 1.0 0.4 10.0 1.2 1.9 2 0 0 2 2 2 0 Secretory lipase SLC35F PF06027.12 EMR65538.1 - 1.7e-96 323.3 23.6 2.2e-96 322.9 23.6 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EMR65538.1 - 6.9e-09 35.1 5.3 6.9e-09 35.1 5.3 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EMR65538.1 - 3.4e-06 27.3 36.1 0.0043 17.2 13.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 EMR65538.1 - 0.7 8.9 9.4 0.074 12.1 2.7 2.3 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS CALM_bind PF16025.5 EMR65539.1 - 0.015 15.7 1.9 0.029 14.8 1.9 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Methyltransf_2 PF00891.18 EMR65540.1 - 6.4e-20 71.3 0.0 1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Glyco_hydro_47 PF01532.20 EMR65541.1 - 3.7e-20 72.3 0.0 4.2e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPR_1 PF00515.28 EMR65542.1 - 2.3e-49 163.3 19.5 4.3e-08 32.6 0.1 9.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 EMR65542.1 - 2.4e-41 136.5 15.1 1e-05 25.3 0.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 EMR65542.1 - 4e-37 123.3 13.8 2.6e-06 27.2 0.0 9.9 9 1 0 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.6 EMR65542.1 - 1.6e-24 84.5 5.9 0.019 15.3 0.0 8.6 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMR65542.1 - 2.4e-24 83.9 7.7 0.00054 20.6 0.0 8.3 4 3 5 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 EMR65542.1 - 1.6e-22 79.8 8.7 0.00021 21.9 0.2 6.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMR65542.1 - 9.7e-22 77.3 8.7 8e-05 23.1 0.0 6.6 5 1 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EMR65542.1 - 1.5e-18 66.9 14.5 3.4e-05 24.0 1.0 7.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 EMR65542.1 - 3.2e-18 65.1 13.7 0.0028 18.2 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EMR65542.1 - 2.8e-17 62.1 23.8 2.8e-06 26.9 0.2 8.3 4 3 4 8 8 8 4 TPR repeat TPR_7 PF13176.6 EMR65542.1 - 1e-16 59.6 10.6 0.0075 16.2 0.1 8.3 7 1 1 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR65542.1 - 2e-15 56.7 7.4 2e-08 34.3 1.2 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EMR65542.1 - 5.2e-12 45.7 8.6 0.00059 19.9 0.1 6.1 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_15 PF13429.6 EMR65542.1 - 1.4e-10 40.9 2.3 0.0038 16.5 0.1 4.4 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_21 PF09976.9 EMR65542.1 - 6.4e-07 29.3 4.6 0.38 10.4 0.0 4.4 2 2 0 3 3 3 3 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 EMR65542.1 - 2.6e-05 24.4 0.1 0.53 10.6 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMR65542.1 - 0.19 11.7 15.4 23 5.0 0.2 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat BTAD PF03704.17 EMR65542.1 - 0.86 10.0 10.8 0.69 10.3 0.1 3.5 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Aldedh PF00171.22 EMR65543.1 - 4.2e-171 569.5 0.4 4.8e-171 569.3 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 EMR65546.1 - 7.1e-17 61.8 2.4 1.7e-12 47.6 0.0 2.2 1 1 1 2 2 2 2 Ribosome recycling factor MFS_1 PF07690.16 EMR65547.1 - 1.1e-26 93.7 62.7 1.6e-26 93.1 40.1 3.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2784 PF10861.8 EMR65547.1 - 5 7.2 12.0 3.2 7.8 0.6 3.9 3 1 0 3 3 3 0 Protein of Unknown function (DUF2784) GFO_IDH_MocA PF01408.22 EMR65548.1 - 1.9e-16 61.0 0.4 5.7e-16 59.4 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EMR65548.1 - 0.079 13.6 0.1 0.18 12.5 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DJ-1_PfpI PF01965.24 EMR65550.1 - 8.1e-13 48.5 0.0 1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EMR65550.1 - 0.0031 17.3 0.0 0.0045 16.8 0.0 1.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_S8 PF00082.22 EMR65551.1 - 8.3e-20 71.2 13.4 1.3e-19 70.6 13.3 1.6 1 1 0 1 1 1 1 Subtilase family Defensin_propep PF00879.18 EMR65551.1 - 0.083 13.2 0.6 0.23 11.7 0.6 1.8 1 0 0 1 1 1 0 Defensin propeptide MF_alpha_N PF05436.11 EMR65551.1 - 0.11 12.4 6.3 0.082 12.8 0.5 2.9 3 1 0 3 3 3 0 Mating factor alpha precursor N-terminus Exo_endo_phos PF03372.23 EMR65552.1 - 4.6e-05 23.1 0.1 0.0001 21.9 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lactamase_B_2 PF12706.7 EMR65552.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Thiolase_N PF00108.23 EMR65553.1 - 1e-16 61.1 0.0 9.2e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMR65553.1 - 1.4e-11 44.1 0.4 5.9e-11 42.1 0.1 2.3 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EMR65553.1 - 8.4e-05 22.4 0.1 0.0045 16.8 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EMR65553.1 - 9.1e-05 22.2 0.2 0.00036 20.2 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR65553.1 - 0.0089 16.0 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Polysacc_lyase PF14099.6 EMR65554.1 - 7.6e-41 140.3 3.5 8.9e-41 140.0 3.5 1.0 1 0 0 1 1 1 1 Polysaccharide lyase P16-Arc PF04699.14 EMR65555.1 - 7e-50 169.4 0.0 8.2e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Tcf25 PF04910.14 EMR65556.1 - 5.7e-59 200.0 0.0 7.9e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 MNR PF15718.5 EMR65556.1 - 0.00082 17.6 6.1 0.0012 17.2 6.1 1.1 1 0 0 1 1 1 1 Protein moonraker YcaO PF02624.16 EMR65556.1 - 0.055 12.7 1.1 0.075 12.3 0.0 1.7 2 0 0 2 2 2 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding BUD22 PF09073.10 EMR65556.1 - 3.7 6.8 36.5 1.1 8.5 17.3 3.2 2 1 1 3 3 3 0 BUD22 Fungal_trans PF04082.18 EMR65557.1 - 1.5e-16 60.2 0.1 2.7e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CRIC_ras_sig PF10534.9 EMR65557.1 - 0.017 15.3 0.0 9.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras Glyco_transf_8 PF01501.20 EMR65558.1 - 7.9e-11 42.0 0.1 5.9e-10 39.1 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 adh_short PF00106.25 EMR65559.1 - 6.1e-36 123.7 0.0 1.5e-28 99.6 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65559.1 - 2.3e-22 79.7 0.0 1.1e-17 64.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR65559.1 - 1.3e-14 54.5 0.0 2.1e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR65559.1 - 0.00088 18.5 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMR65559.1 - 0.0097 15.4 0.2 0.024 14.1 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SPO22 PF08631.10 EMR65559.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like GDP_Man_Dehyd PF16363.5 EMR65559.1 - 0.041 13.3 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMR65559.1 - 0.071 13.0 0.0 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H-binding Methyltransf_11 PF08241.12 EMR65560.1 - 1.1e-07 32.4 0.0 1.7e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR65560.1 - 5.7e-07 29.5 0.0 7.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR65560.1 - 7.1e-05 23.5 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR65560.1 - 0.00072 20.2 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR65560.1 - 0.00088 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF5640 PF18692.1 EMR65561.1 - 0.075 13.1 0.5 3.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5640) Nup54_57_C PF18570.1 EMR65561.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain TBCA PF02970.16 EMR65561.1 - 0.095 13.0 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF1764 PF08576.10 EMR65561.1 - 0.6 11.0 4.2 0.3 12.0 0.8 2.2 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) HMA PF00403.26 EMR65562.1 - 1.7e-14 54.0 0.8 2.2e-14 53.7 0.8 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Glyco_hydro_64 PF16483.5 EMR65563.1 - 8.8e-102 341.1 0.0 1e-101 340.9 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DnaJ PF00226.31 EMR65564.1 - 8.2e-13 48.3 0.0 2.1e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain CorA PF01544.18 EMR65564.1 - 0.016 14.5 0.5 0.022 14.1 0.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HNHc_6 PF16784.5 EMR65564.1 - 0.096 12.2 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease Afi1 PF07792.12 EMR65564.1 - 1.1 9.8 4.8 0.75 10.3 2.7 1.8 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4140 PF13600.6 EMR65564.1 - 3 8.3 7.0 89 3.6 7.0 2.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Adaptin_N PF01602.20 EMR65565.1 - 1.5e-122 409.8 7.8 1.8e-122 409.6 7.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EMR65565.1 - 1.7e-45 153.8 0.0 4.9e-45 152.4 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EMR65565.1 - 1.1e-14 54.6 0.0 2.1e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Apc13p PF05839.11 EMR65566.1 - 7.6e-35 119.0 0.3 8.8e-35 118.8 0.3 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.16 EMR65567.1 - 1.7e-37 128.4 0.0 2e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO PF00650.20 EMR65568.1 - 9.4e-43 145.7 0.0 1.7e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMR65568.1 - 5.9e-13 48.8 1.4 1.3e-12 47.7 1.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EMR65568.1 - 0.0017 18.5 0.0 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Vasculin PF15337.6 EMR65568.1 - 0.33 11.8 1.3 15 6.5 0.1 2.5 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Pol_alpha_B_N PF08418.10 EMR65569.1 - 1.2e-69 235.0 4.7 2.8e-42 145.4 0.4 2.1 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EMR65569.1 - 5e-16 58.7 0.0 8.5e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Flavokinase PF01687.17 EMR65571.1 - 8.2e-34 116.3 0.0 1.1e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Macoilin PF09726.9 EMR65571.1 - 0.15 10.6 0.4 0.16 10.5 0.4 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 EMR65571.1 - 0.16 11.1 8.2 0.18 10.9 8.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein CCDC53 PF10152.9 EMR65571.1 - 0.48 10.8 6.3 0.7 10.3 6.3 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1180 PF06679.12 EMR65571.1 - 1.1 9.7 6.6 1.7 9.0 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Presenilin PF01080.17 EMR65571.1 - 3.1 6.5 4.3 3.9 6.1 4.3 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 EMR65571.1 - 5 7.8 11.8 8.4 7.0 11.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4551 PF15087.6 EMR65571.1 - 7.5 5.3 5.6 9.5 4.9 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SPX PF03105.19 EMR65573.1 - 2.7e-17 63.8 19.3 1.5e-10 41.6 1.7 3.2 1 1 2 3 3 3 3 SPX domain Ank_4 PF13637.6 EMR65573.1 - 2.2e-07 31.3 0.1 5e-05 23.8 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR65573.1 - 1.4e-06 28.8 0.1 7e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR65573.1 - 3.7e-06 27.1 0.3 0.00046 20.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR65573.1 - 0.00083 19.6 0.2 0.051 14.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EMR65573.1 - 0.029 14.8 0.2 0.2 12.2 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat MFS_1 PF07690.16 EMR65575.1 - 7.1e-34 117.3 36.0 7.1e-34 117.3 36.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ABM PF03992.16 EMR65576.1 - 7.6e-05 22.8 0.5 0.00011 22.2 0.5 1.3 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Citrate_synt PF00285.21 EMR65577.1 - 1.4e-99 333.6 0.0 1.9e-99 333.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EMR65577.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Fungal_trans PF04082.18 EMR65579.1 - 1.9e-07 30.4 0.2 3.1e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3446 PF11928.8 EMR65579.1 - 3.1 8.2 8.3 3.1 8.2 2.4 2.9 2 0 0 2 2 2 0 Early growth response N-terminal domain Cnn_1N PF07989.11 EMR65580.1 - 4.5e-08 33.1 5.0 4.5e-08 33.1 5.0 1.9 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 TAP42 PF04177.12 EMR65580.1 - 0.0072 15.5 1.3 0.0098 15.0 1.3 1.1 1 0 0 1 1 1 1 TAP42-like family ZapB PF06005.12 EMR65580.1 - 0.013 15.9 6.5 1.7 9.1 2.7 2.9 2 1 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 EMR65580.1 - 0.027 14.6 1.5 0.027 14.6 1.5 2.8 2 1 1 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.15 EMR65580.1 - 0.056 13.5 3.2 0.056 13.5 3.2 2.9 2 1 0 3 3 3 0 Basic region leucine zipper DUF4407 PF14362.6 EMR65580.1 - 0.12 11.7 0.3 0.15 11.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EMR65580.1 - 0.3 11.1 1.4 0.75 9.8 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 EMR65580.1 - 5 7.2 7.5 27 4.8 7.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPX2 PF06886.11 EMR65580.1 - 6.6 7.1 10.0 1.1 9.6 5.2 2.1 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) E1-E2_ATPase PF00122.20 EMR65581.1 - 3.8e-48 163.4 6.2 8.8e-48 162.2 4.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMR65581.1 - 8.3e-17 62.2 0.1 3.8e-16 60.0 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMR65581.1 - 3.8e-10 39.3 0.0 9.4e-10 38.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMR65581.1 - 0.0024 17.7 0.1 0.0047 16.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase O-antigen_lig PF13425.6 EMR65581.1 - 0.38 9.5 5.2 0.76 8.5 5.2 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CTD_bind PF04818.13 EMR65582.1 - 1.4e-09 38.6 0.0 2.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EMR65582.1 - 1.2e-05 25.1 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 EMR65583.1 - 1.6e-27 95.2 3.4 4.3e-12 45.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MatE PF01554.18 EMR65584.1 - 0.0017 18.0 0.2 0.0023 17.6 0.2 1.2 1 0 0 1 1 1 1 MatE PDCD2_C PF04194.13 EMR65585.1 - 4.7e-44 150.5 4.4 3.2e-43 147.8 0.0 3.4 4 0 0 4 4 4 1 Programmed cell death protein 2, C-terminal putative domain DUF737 PF05300.11 EMR65585.1 - 0.036 14.4 0.3 0.036 14.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Ribosomal_60s PF00428.19 EMR65585.1 - 0.48 11.0 4.8 2.8 8.6 1.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein BEX PF04538.12 EMR65585.1 - 1 10.0 6.7 1.1 9.9 5.5 1.7 1 1 0 1 1 1 0 Brain expressed X-linked like family MgtE_N PF03448.17 EMR65586.1 - 0.0093 16.6 5.1 1.2 9.7 0.3 2.1 1 1 1 2 2 2 2 MgtE intracellular N domain Fe_dep_repress PF01325.19 EMR65586.1 - 0.062 13.5 0.4 26 5.1 0.0 4.2 2 2 2 4 4 4 0 Iron dependent repressor, N-terminal DNA binding domain BslA PF17735.1 EMR65586.1 - 0.069 13.1 0.3 0.069 13.1 0.3 2.2 1 1 1 2 2 2 0 Biofilm surface layer A AbiEi_4 PF13338.6 EMR65586.1 - 0.46 10.7 10.5 23 5.2 0.1 4.5 1 1 1 2 2 2 0 Transcriptional regulator, AbiEi antitoxin TBCC PF07986.12 EMR65588.1 - 8.1e-29 99.8 0.0 1.2e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C RuBisCo_chap_C PF18087.1 EMR65588.1 - 0.12 12.0 1.9 0.15 11.7 0.9 1.6 1 1 0 1 1 1 0 Rubisco Assembly chaperone C-terminal domain DUF3439 PF11921.8 EMR65588.1 - 0.35 10.8 5.8 0.66 9.9 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EMR65588.1 - 1.6 6.6 6.2 2 6.3 6.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein G_path_suppress PF15991.5 EMR65588.1 - 1.9 8.5 5.9 2.9 8.0 5.9 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor Chitin_synth_1 PF01644.17 EMR65589.1 - 4.6e-67 225.0 0.0 6.6e-67 224.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EMR65589.1 - 1.5e-26 92.1 0.0 3.3e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EMR65589.1 - 8.1e-25 87.4 0.1 3e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EMR65589.1 - 2.9e-10 40.4 2.1 1.2e-09 38.3 2.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF2070 PF09843.9 EMR65589.1 - 1.1 7.4 7.1 1.8 6.8 7.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Med9 PF07544.13 EMR65590.1 - 1.1e-15 57.5 0.2 1.8e-15 56.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 EMR65590.1 - 0.0014 18.9 2.8 0.0025 18.1 2.8 1.5 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Phage_GP20 PF06810.11 EMR65590.1 - 0.045 13.5 0.1 0.067 13.0 0.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF812 PF05667.11 EMR65590.1 - 0.085 11.7 0.1 0.095 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TFIIA PF03153.13 EMR65590.1 - 0.13 12.2 5.0 0.15 12.1 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EMR65590.1 - 0.16 12.7 8.9 0.22 12.1 8.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1178 PF06676.11 EMR65590.1 - 0.17 12.3 5.3 0.41 11.0 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Dicty_REP PF05086.12 EMR65590.1 - 0.31 9.0 6.2 0.37 8.7 6.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med13_C PF06333.12 EMR65590.1 - 0.72 9.1 10.5 0.95 8.7 10.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF2981 PF11200.8 EMR65590.1 - 3.5 7.3 6.4 4.6 6.9 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Med3 PF11593.8 EMR65590.1 - 3.8 6.6 17.4 4.6 6.3 17.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ndc1_Nup PF09531.10 EMR65590.1 - 5.5 5.6 6.4 5.9 5.5 6.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup iPGM_N PF06415.13 EMR65591.1 - 1.6e-79 266.4 0.0 2.4e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EMR65591.1 - 4.6e-66 222.7 0.0 5.2e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EMR65591.1 - 9.7e-06 25.2 0.0 5.4e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EMR65591.1 - 0.0005 19.8 0.0 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase CSN8_PSD8_EIF3K PF10075.9 EMR65592.1 - 1.5e-39 135.3 0.0 2.1e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family MFS_1 PF07690.16 EMR65593.1 - 1.2e-12 47.4 41.2 6.9e-07 28.5 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HATPase_c PF02518.26 EMR65594.1 - 2.2e-21 76.5 0.0 6.2e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMR65594.1 - 1.7e-15 57.1 0.0 4.2e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 EMR65594.1 - 4.3e-08 33.3 0.6 0.00039 20.7 0.2 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EMR65594.1 - 2.8e-07 30.4 0.0 0.0059 16.6 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.7 EMR65594.1 - 0.0043 17.3 0.0 1.9 8.8 0.0 2.9 2 0 0 2 2 2 2 PAS domain Fer2 PF00111.27 EMR65595.1 - 7.7e-12 45.0 1.5 4.1e-11 42.7 1.8 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain MOSC PF03473.17 EMR65595.1 - 2.1e-09 37.5 0.0 5.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 MOSC domain NAD_binding_6 PF08030.12 EMR65595.1 - 0.0008 19.6 0.7 0.032 14.4 0.1 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain 3-alpha PF03475.14 EMR65595.1 - 0.00098 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 3-alpha domain Transferase PF02458.15 EMR65596.1 - 1.6e-26 93.0 0.0 2e-10 39.9 0.0 3.1 3 0 0 3 3 3 3 Transferase family Aldo_ket_red PF00248.21 EMR65597.1 - 3.2e-57 194.0 0.0 4.1e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UFD1 PF03152.14 EMR65598.1 - 5.8e-30 104.0 0.0 5.6e-14 52.0 0.0 3.4 2 1 1 3 3 3 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EMR65598.1 - 7.2e-07 29.4 0.2 7.2e-07 29.4 0.2 2.6 3 0 0 3 3 3 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-Mss51 PF13824.6 EMR65598.1 - 6.5 6.9 11.9 2.3 8.4 3.6 3.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Aldose_epim PF01263.20 EMR65599.1 - 2.2e-45 155.3 0.0 2.4e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Actin PF00022.19 EMR65600.1 - 3.1e-99 332.3 0.0 2.4e-98 329.4 0.0 1.9 1 1 0 1 1 1 1 Actin DUF3293 PF11697.8 EMR65601.1 - 0.046 14.2 1.1 1.3 9.5 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3293) zf-B_box PF00643.24 EMR65601.1 - 5.2 7.3 9.0 2.2 8.5 5.3 2.2 2 0 0 2 2 2 0 B-box zinc finger CDH-cyt PF16010.5 EMR65602.1 - 1e-51 175.2 0.1 1.3e-51 174.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase adh_short_C2 PF13561.6 EMR65603.1 - 1.1e-58 198.6 0.2 1.2e-58 198.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR65603.1 - 1.6e-41 141.9 0.4 2e-41 141.6 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR65603.1 - 6.4e-11 42.5 0.4 1.1e-10 41.8 0.4 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR65603.1 - 0.00051 19.6 0.1 0.00068 19.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EMR65603.1 - 0.005 16.2 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMR65603.1 - 0.0053 17.0 0.2 0.0092 16.2 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EMR65603.1 - 0.0068 15.6 0.0 0.0091 15.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMR65603.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EMR65603.1 - 0.023 14.8 0.2 0.036 14.2 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 EMR65603.1 - 0.13 12.4 0.0 0.45 10.6 0.0 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 EMR65603.1 - 0.2 11.2 0.7 0.38 10.3 0.6 1.5 2 0 0 2 2 2 0 NmrA-like family Sugar_tr PF00083.24 EMR65604.1 - 3.8e-91 306.2 20.2 4.5e-91 306.0 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR65604.1 - 3.2e-26 92.1 30.4 6.9e-25 87.7 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GP41 PF00517.17 EMR65604.1 - 0.43 10.5 4.2 4.2 7.2 0.6 3.2 3 0 0 3 3 3 0 Retroviral envelope protein ADH_N PF08240.12 EMR65605.1 - 1e-31 109.0 0.3 1e-31 109.0 0.3 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR65605.1 - 5e-25 88.0 0.4 9.6e-25 87.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR65605.1 - 9.7e-08 31.8 0.3 2.9e-06 27.0 0.3 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMR65605.1 - 4e-07 31.2 0.3 1.7e-06 29.1 0.0 2.3 3 1 0 3 3 3 1 Zinc-binding dehydrogenase CMAS PF02353.20 EMR65605.1 - 0.00023 20.6 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EMR65605.1 - 0.0011 19.7 0.0 0.0023 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EMR65605.1 - 0.0047 16.3 0.1 0.0078 15.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 EMR65605.1 - 0.019 15.6 0.0 0.041 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 EMR65605.1 - 0.04 13.5 0.1 0.074 12.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.21 EMR65605.1 - 0.48 10.5 2.7 2.2 8.4 0.8 2.4 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AAA_33 PF13671.6 EMR65606.1 - 9.6e-06 25.8 0.1 3.6e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMR65606.1 - 6.1e-05 22.7 0.1 9.5e-05 22.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EMR65606.1 - 0.00026 20.8 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EMR65606.1 - 0.0007 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMR65606.1 - 0.00081 19.7 0.0 0.0016 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EMR65606.1 - 0.00089 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.12 EMR65606.1 - 0.0012 18.2 0.1 0.0026 17.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EMR65606.1 - 0.0013 19.3 0.0 0.0021 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EMR65606.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 EMR65606.1 - 0.002 18.5 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 EMR65606.1 - 0.0035 17.0 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EMR65606.1 - 0.0087 16.4 0.5 0.029 14.7 0.5 1.9 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EMR65606.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 EMR65606.1 - 0.012 15.3 0.2 0.022 14.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EMR65606.1 - 0.013 15.5 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 EMR65606.1 - 0.014 15.4 0.0 0.035 14.0 0.0 1.7 2 0 0 2 2 1 0 NTPase ArsA_ATPase PF02374.15 EMR65606.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_16 PF13191.6 EMR65606.1 - 0.015 15.7 0.0 0.04 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DnaB_C PF03796.15 EMR65606.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_28 PF13521.6 EMR65606.1 - 0.021 15.1 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EMR65606.1 - 0.024 14.7 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EMR65606.1 - 0.025 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 EMR65606.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein KTI12 PF08433.10 EMR65606.1 - 0.053 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.6 EMR65606.1 - 0.069 13.6 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EMR65606.1 - 0.084 13.3 0.1 0.26 11.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 EMR65606.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EMR65606.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 EMR65606.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 EMR65606.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 2 0 0 2 2 1 0 FtsK/SpoIIIE family TsaE PF02367.17 EMR65606.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EMR65606.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 EMR65606.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 EMR65606.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EMR65606.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 KaiC Stimulus_sens_1 PF13756.6 EMR65607.1 - 0.016 15.8 0.0 0.061 13.9 0.0 1.8 2 0 0 2 2 2 0 Stimulus-sensing domain Ubiquitin_2 PF14560.6 EMR65607.1 - 0.17 12.4 0.0 0.55 10.7 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain OPT PF03169.15 EMR65608.1 - 3.2e-129 432.3 33.8 3.7e-129 432.2 33.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.25 EMR65609.1 - 7.3e-51 173.1 0.0 1.1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR65609.1 - 9.8e-30 103.7 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR65609.1 - 1.5e-09 37.6 0.0 2.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMR65609.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR65609.1 - 0.046 13.6 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Bravo_FIGEY PF13882.6 EMR65610.1 - 0.084 14.3 0.8 0.33 12.4 0.8 2.0 1 0 0 1 1 1 0 Bravo-like intracellular region Aa_trans PF01490.18 EMR65611.1 - 3e-45 154.6 24.7 8.5e-23 80.7 10.1 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EMR65611.1 - 0.0001 21.5 20.1 0.0038 16.3 5.7 2.2 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family ATP-synt_DE_N PF02823.16 EMR65612.1 - 1.8e-18 66.2 0.0 2.6e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain EnY2 PF10163.9 EMR65613.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 Macoilin PF09726.9 EMR65613.1 - 0.086 11.4 7.9 0.1 11.2 7.9 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 EMR65613.1 - 0.24 10.6 12.3 0.25 10.5 12.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein HNF-1_N PF04814.13 EMR65613.1 - 0.26 11.9 8.9 0.38 11.3 8.9 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Menin PF05053.13 EMR65613.1 - 0.26 9.6 6.1 0.28 9.5 6.1 1.3 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 EMR65613.1 - 0.6 8.8 4.7 0.73 8.5 4.7 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 EMR65613.1 - 2.2 7.6 9.7 2.9 7.2 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BAF1_ABF1 PF04684.13 EMR65613.1 - 3.3 6.7 14.5 4.2 6.3 14.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SRP-alpha_N PF04086.13 EMR65613.1 - 9.5 6.0 11.8 13 5.6 11.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ABC_membrane PF00664.23 EMR65614.1 - 5.3e-34 118.1 6.7 8.4e-34 117.5 6.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMR65614.1 - 9.1e-34 116.9 0.0 1.9e-33 115.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMR65614.1 - 0.0015 18.1 0.1 0.03 13.7 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMR65614.1 - 0.0089 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EMR65614.1 - 0.015 15.0 0.1 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 EMR65614.1 - 0.015 14.4 0.1 0.042 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 EMR65614.1 - 0.035 14.3 1.4 0.38 11.0 0.2 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 EMR65614.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FAM220 PF15487.6 EMR65615.1 - 6 6.4 9.6 1.4 8.5 6.1 1.6 2 0 0 2 2 2 0 FAM220 family FAM76 PF16046.5 EMR65615.1 - 6.9 5.9 10.4 3.7 6.8 7.8 1.8 2 0 0 2 2 2 0 FAM76 protein Arf PF00025.21 EMR65616.1 - 1.4e-66 223.3 0.0 1.5e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EMR65616.1 - 3e-12 46.4 0.1 1.2e-08 34.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EMR65616.1 - 2.3e-08 33.7 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EMR65616.1 - 5.9e-08 33.0 0.0 1.9e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EMR65616.1 - 2.1e-07 31.0 0.0 2.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EMR65616.1 - 7.8e-07 28.8 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EMR65616.1 - 1.4e-05 24.6 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMR65616.1 - 0.0079 15.7 0.1 0.34 10.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EMR65617.1 - 2.2e-97 322.6 0.0 2.3e-47 160.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMR65617.1 - 5.5e-25 86.9 2.2 9.9e-13 47.7 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EMR65617.1 - 1.1e-18 67.2 0.3 4.2e-18 65.3 0.3 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EMR65617.1 - 3.4e-14 52.9 0.0 3.2e-06 27.0 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMR65617.1 - 1e-13 51.8 0.0 2.2e-07 31.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EMR65617.1 - 1.9e-12 47.9 0.0 0.0012 19.3 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 EMR65617.1 - 5.6e-12 46.0 0.0 6.1e-05 23.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 EMR65617.1 - 1.1e-11 44.9 0.6 5.3e-06 26.5 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMR65617.1 - 1.4e-09 38.3 0.4 0.024 14.9 0.0 4.1 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 EMR65617.1 - 3.1e-09 36.5 0.1 0.0011 18.3 0.0 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EMR65617.1 - 6.9e-08 32.2 0.0 1.8e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 EMR65617.1 - 1.8e-07 31.1 0.0 0.011 15.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EMR65617.1 - 2.2e-07 31.5 0.0 0.028 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EMR65617.1 - 2.3e-07 30.4 0.3 0.008 15.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMR65617.1 - 3e-07 30.2 4.5 0.39 10.3 0.1 4.8 3 2 1 5 5 5 3 AAA domain ATPase PF06745.13 EMR65617.1 - 5.8e-07 29.1 0.3 0.25 10.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_14 PF13173.6 EMR65617.1 - 7.8e-07 29.2 0.0 0.0085 16.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EMR65617.1 - 1.1e-06 28.0 0.0 0.0019 17.4 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EMR65617.1 - 1.7e-06 28.4 0.0 0.092 13.1 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_7 PF12775.7 EMR65617.1 - 2.5e-06 27.1 0.0 0.045 13.3 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 EMR65617.1 - 4.4e-06 26.6 0.2 4.7e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 EMR65617.1 - 1.3e-05 25.5 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EMR65617.1 - 1.4e-05 25.6 0.0 0.18 12.3 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_24 PF13479.6 EMR65617.1 - 2.3e-05 24.2 0.0 0.083 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 EMR65617.1 - 3.3e-05 23.1 0.0 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EMR65617.1 - 4.1e-05 23.3 0.0 0.29 10.8 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 EMR65617.1 - 8.8e-05 22.4 0.0 0.16 11.8 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein TsaE PF02367.17 EMR65617.1 - 0.00014 21.9 0.0 0.87 9.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EMR65617.1 - 0.00014 21.4 0.3 0.41 10.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 EMR65617.1 - 0.00019 21.5 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EMR65617.1 - 0.00032 20.6 0.0 0.67 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EMR65617.1 - 0.00034 21.1 0.0 0.6 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMR65617.1 - 0.00037 20.4 0.1 0.44 10.5 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 EMR65617.1 - 0.00065 19.5 0.3 1.5 8.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EMR65617.1 - 0.001 18.9 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EMR65617.1 - 0.0011 19.4 0.5 5.6 7.3 0.0 3.7 3 1 1 4 4 3 0 AAA domain ATPase_2 PF01637.18 EMR65617.1 - 0.002 18.1 0.0 1.9 8.3 0.0 3.7 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EMR65617.1 - 0.0037 17.4 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 EMR65617.1 - 0.0043 16.3 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EMR65617.1 - 0.0055 16.6 0.7 2.6 7.9 0.0 3.9 4 0 0 4 4 3 1 NTPase Zeta_toxin PF06414.12 EMR65617.1 - 0.0063 15.8 0.5 7.7 5.7 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin Viral_helicase1 PF01443.18 EMR65617.1 - 0.0066 16.2 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 EMR65617.1 - 0.012 14.9 0.0 0.91 8.7 0.0 3.0 2 1 1 3 3 3 0 KAP family P-loop domain NB-ARC PF00931.22 EMR65617.1 - 0.012 14.8 0.0 3.9 6.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain IPT PF01745.16 EMR65617.1 - 0.012 15.0 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_6 PF12774.7 EMR65617.1 - 0.056 12.4 0.1 7.6 5.4 0.0 2.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region UFD1 PF03152.14 EMR65617.1 - 0.059 12.8 0.0 0.36 10.3 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 EMR65617.1 - 0.063 13.0 0.0 12 5.5 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 EMR65617.1 - 0.12 11.3 0.0 13 4.5 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Zot PF05707.12 EMR65617.1 - 0.15 11.6 0.0 2.4 7.7 0.0 2.9 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) TRAM_LAG1_CLN8 PF03798.16 EMR65618.1 - 4.1e-37 127.8 22.7 4.1e-37 127.8 22.7 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EMR65618.1 - 1.9e-27 94.7 0.0 4.5e-27 93.5 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein SARAF PF06682.12 EMR65618.1 - 0.24 11.0 3.2 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2457 PF10446.9 EMR65619.1 - 2.9e-112 376.2 50.7 4.6e-92 309.6 34.4 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF2457) Brix PF04427.18 EMR65621.1 - 6.6e-39 134.0 0.0 8.2e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain Arb2 PF09757.9 EMR65622.1 - 5.3e-97 324.0 0.0 7.2e-97 323.6 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EMR65622.1 - 4.6e-82 275.9 0.0 6.7e-82 275.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Troponin PF00992.20 EMR65623.1 - 0.00085 19.6 2.9 0.0018 18.6 2.9 1.4 1 0 0 1 1 1 1 Troponin F-box PF00646.33 EMR65624.1 - 0.0057 16.5 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ras PF00071.22 EMR65625.1 - 2.7e-63 212.4 0.2 3.2e-63 212.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR65625.1 - 2.8e-35 121.1 0.2 3.9e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR65625.1 - 4.7e-13 49.0 0.1 6e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMR65625.1 - 7.8e-08 32.4 0.1 1.2e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMR65625.1 - 0.00033 20.2 0.1 0.0019 17.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMR65625.1 - 0.00043 19.7 0.1 0.00069 19.0 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EMR65625.1 - 0.00054 19.9 1.0 0.017 15.0 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EMR65625.1 - 0.003 17.9 0.0 0.019 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EMR65625.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EMR65625.1 - 0.017 15.1 0.1 0.046 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR65625.1 - 0.017 15.5 0.1 0.029 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EMR65625.1 - 0.022 15.3 0.1 0.039 14.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EMR65625.1 - 0.029 14.1 0.1 0.064 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EMR65625.1 - 0.033 13.6 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 EMR65625.1 - 0.093 12.5 0.5 0.12 12.1 0.4 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 EMR65625.1 - 0.098 12.2 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B SpoIIID PF12116.8 EMR65625.1 - 0.099 12.7 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_7 PF12775.7 EMR65625.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HET PF06985.11 EMR65626.1 - 1.8e-09 38.1 0.0 5.4e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TauD PF02668.16 EMR65627.1 - 2.9e-49 168.3 1.0 3.6e-36 125.4 0.1 2.3 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.22 EMR65628.1 - 1.4e-27 96.6 0.0 1.7e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.17 EMR65629.1 - 4.9e-31 107.7 0.2 6.3e-31 107.4 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase GSAP-16 PF14959.6 EMR65629.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term p450 PF00067.22 EMR65630.1 - 5.5e-57 193.5 0.0 7.9e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EMR65631.1 - 6.5e-50 170.2 0.0 9.9e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EMR65632.1 - 2.2e-20 72.9 29.0 7.9e-19 67.8 29.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 EMR65633.1 - 5.3e-32 111.4 1.1 2.7e-31 109.1 1.1 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR65633.1 - 8.1e-07 29.2 0.9 2.8e-06 27.5 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR65633.1 - 3.2e-06 26.6 0.4 0.00028 20.3 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR65633.1 - 1e-05 24.8 0.9 0.0096 15.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EMR65633.1 - 1.9e-05 24.1 0.4 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR65633.1 - 3.1e-05 23.5 0.5 0.15 11.3 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 EMR65633.1 - 8.6e-05 22.3 2.0 0.00033 20.4 1.5 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR65633.1 - 0.00041 20.8 1.1 0.0048 17.4 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR65633.1 - 0.00052 18.8 0.2 0.0031 16.3 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EMR65633.1 - 0.00099 18.3 1.0 0.0021 17.2 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EMR65633.1 - 0.001 18.3 1.0 0.0034 16.5 1.0 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMR65633.1 - 0.0031 16.9 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR65633.1 - 0.041 12.7 0.0 0.08 11.8 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 EMR65633.1 - 0.044 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EMR65633.1 - 0.17 12.2 0.1 0.8 10.0 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain p450 PF00067.22 EMR65634.1 - 3.2e-08 32.8 0.0 5.6e-08 32.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SUR7 PF06687.12 EMR65635.1 - 6.7e-33 114.1 6.0 9.2e-33 113.7 6.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF4064 PF13273.6 EMR65635.1 - 8 6.8 18.9 0.053 13.8 1.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) p450 PF00067.22 EMR65637.1 - 6.7e-37 127.3 0.1 8.2e-37 127.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_21 PF05050.12 EMR65638.1 - 2.1e-17 63.7 0.0 3.3e-17 63.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 EMR65638.1 - 0.003 16.9 0.0 0.057 12.7 0.0 2.0 2 0 0 2 2 2 1 Vibrio cholerae RfbT protein Met_10 PF02475.16 EMR65638.1 - 0.0032 17.3 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EMR65638.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SnoaL_2 PF12680.7 EMR65639.1 - 0.00052 20.6 0.0 0.00068 20.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EMR65639.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_4 PF13577.6 EMR65639.1 - 0.072 13.2 0.0 0.08 13.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Transferase PF02458.15 EMR65640.1 - 7e-05 21.6 0.0 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 Transferase family adh_short PF00106.25 EMR65641.1 - 3.9e-14 52.6 0.0 1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65641.1 - 1e-09 38.3 0.0 2.2e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR65641.1 - 6e-06 26.3 0.0 2.3e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 KR domain UDPGT PF00201.18 EMR65641.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase HTH_51 PF18558.1 EMR65642.1 - 4e-30 103.5 0.0 7.6e-30 102.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_12 PF08242.12 EMR65642.1 - 7.2e-16 58.8 0.0 2.2e-15 57.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR65642.1 - 2.8e-13 50.0 0.0 5.1e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 EMR65642.1 - 3.3e-12 46.7 0.1 9.2e-12 45.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 EMR65642.1 - 1.7e-11 44.6 0.0 4.5e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR65642.1 - 1.2e-09 38.1 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR65642.1 - 4.5e-07 30.4 0.0 1.1e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.21 EMR65642.1 - 1.6e-05 24.5 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ubie_methyltran PF01209.18 EMR65642.1 - 0.00013 21.4 0.0 0.00034 20.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 EMR65642.1 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_28 PF02636.17 EMR65642.1 - 0.0076 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DLH PF01738.18 EMR65642.1 - 0.01 15.4 0.0 0.043 13.4 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Thioesterase PF00975.20 EMR65642.1 - 0.019 15.1 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain COesterase PF00135.28 EMR65642.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Hydrolase_4 PF12146.8 EMR65642.1 - 0.11 11.8 0.1 0.3 10.3 0.0 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EMR65642.1 - 0.14 12.0 0.0 4.8 6.9 0.0 2.2 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase GDP_Man_Dehyd PF16363.5 EMR65643.1 - 6.1e-81 272.4 0.0 2.2e-57 194.9 0.0 2.1 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMR65643.1 - 1.2e-26 93.6 0.0 2.6e-14 53.3 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMR65643.1 - 0.014 14.5 0.0 0.031 13.4 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RRM_1 PF00076.22 EMR65644.1 - 0.00044 20.0 0.0 0.00093 19.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Terpene_synth_C PF03936.16 EMR65645.1 - 9.4e-05 21.9 0.5 0.00013 21.4 0.5 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Carn_acyltransf PF00755.20 EMR65646.1 - 1.4e-100 337.6 0.0 1.9e-100 337.2 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 EMR65646.1 - 6.7e-71 238.8 0.0 1.6e-70 237.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EMR65646.1 - 1.9e-58 198.5 0.3 5.6e-58 196.9 0.3 1.8 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EMR65646.1 - 8.2e-58 196.0 0.0 1.6e-57 195.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EMR65646.1 - 1.8e-44 151.8 1.5 3.8e-44 150.7 0.2 2.3 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.22 EMR65646.1 - 7.3e-38 129.2 0.1 2.9e-37 127.3 0.1 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR65646.1 - 2e-20 73.3 0.0 2.6e-19 69.7 0.0 2.5 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EMR65646.1 - 5e-10 40.0 0.1 3.3e-09 37.4 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 EMR65646.1 - 7.1e-09 35.9 0.1 2e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EMR65646.1 - 5.4e-07 29.6 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR65646.1 - 1.1e-05 26.0 0.0 0.00015 22.3 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR65646.1 - 2.2e-05 25.1 0.0 0.00021 21.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR65646.1 - 6.9e-05 22.7 0.0 0.00027 20.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 EMR65646.1 - 7.1e-05 22.8 0.0 0.00064 19.7 0.0 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 EMR65646.1 - 0.00073 18.9 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 EMR65646.1 - 0.0016 17.9 0.7 0.0037 16.7 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.12 EMR65646.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Calici_coat PF00915.20 EMR65647.1 - 0.0011 17.9 0.1 0.0013 17.7 0.1 1.1 1 0 0 1 1 1 1 Calicivirus coat protein DUF3142 PF11340.8 EMR65648.1 - 0.023 14.5 0.2 0.051 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) DUF4685 PF15737.5 EMR65648.1 - 0.47 10.9 3.1 0.48 10.9 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) AAA PF00004.29 EMR65649.1 - 5.4e-41 140.1 0.1 6.2e-16 59.0 0.0 4.8 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 EMR65649.1 - 5.1e-36 124.2 0.8 1.9e-35 122.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_lid_6 PF17866.1 EMR65649.1 - 3.5e-17 62.3 4.5 1.3e-07 31.7 0.2 3.5 3 0 0 3 3 2 2 AAA lid domain AAA_11 PF13086.6 EMR65649.1 - 3.6e-14 53.2 35.6 8.4e-13 48.7 0.0 6.6 6 0 0 6 6 5 2 AAA domain AAA_30 PF13604.6 EMR65649.1 - 3.1e-13 49.9 0.7 0.045 13.5 0.0 4.8 4 0 0 4 4 4 4 AAA domain AAA_19 PF13245.6 EMR65649.1 - 5.9e-10 39.7 1.9 0.93 9.8 0.0 5.1 4 0 0 4 4 4 3 AAA domain AAA_5 PF07728.14 EMR65649.1 - 1.4e-09 38.1 0.5 0.067 13.2 0.0 4.4 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMR65649.1 - 1.4e-09 38.3 8.0 0.038 14.3 0.7 6.4 3 3 1 4 4 4 3 AAA domain Mg_chelatase PF01078.21 EMR65649.1 - 1.3e-08 34.4 0.0 0.046 13.1 0.0 3.6 3 0 0 3 3 3 3 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EMR65649.1 - 2e-08 34.3 0.1 0.061 13.0 0.0 5.2 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EMR65649.1 - 2.4e-07 31.3 1.1 0.26 11.7 0.0 4.7 4 0 0 4 4 3 2 AAA ATPase domain RuvB_N PF05496.12 EMR65649.1 - 7.9e-07 28.9 0.0 0.31 10.8 0.0 3.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EMR65649.1 - 1e-05 26.1 1.2 2.6 8.6 0.0 4.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EMR65649.1 - 1.5e-05 25.3 0.1 1.8 9.0 0.0 3.9 3 0 0 3 3 3 2 RNA helicase IstB_IS21 PF01695.17 EMR65649.1 - 1.7e-05 24.6 0.0 2.6 7.7 0.0 3.6 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_7 PF12775.7 EMR65649.1 - 1.9e-05 24.3 0.4 0.41 10.1 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_33 PF13671.6 EMR65649.1 - 0.00034 20.8 7.5 0.68 10.1 0.0 4.4 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 EMR65649.1 - 0.0004 20.2 12.1 0.36 10.5 0.0 5.0 5 1 0 5 5 5 3 AAA domain Torsin PF06309.11 EMR65649.1 - 0.00064 19.8 0.0 10 6.2 0.0 3.6 3 0 0 3 3 3 0 Torsin Sigma54_activat PF00158.26 EMR65649.1 - 0.0018 18.0 0.1 10 5.8 0.0 3.8 3 0 0 3 3 3 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EMR65649.1 - 0.005 16.8 1.5 20 5.1 0.0 3.8 3 0 0 3 3 3 0 NTPase AAA_6 PF12774.7 EMR65649.1 - 0.096 11.6 0.3 4.2 6.2 0.1 3.1 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region SRP54 PF00448.22 EMR65649.1 - 0.13 11.9 3.5 0.62 9.7 0.1 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EMR65649.1 - 0.29 11.4 12.8 2.3 8.4 0.0 4.8 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.27 EMR65649.1 - 6.1 7.4 8.8 60 4.2 0.0 4.6 4 0 0 4 4 4 0 ABC transporter Aldo_ket_red PF00248.21 EMR65650.1 - 2e-69 234.1 0.1 2.5e-69 233.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CDH-cyt PF16010.5 EMR65651.1 - 2.9e-55 186.8 0.5 9e-55 185.2 0.1 2.0 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EMR65651.1 - 2.5e-25 89.4 0.0 4.2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR65651.1 - 1.9e-21 77.1 1.0 3.8e-21 76.1 1.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR65651.1 - 2.5e-08 33.4 0.3 7e-07 28.7 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EMR65651.1 - 5.6e-07 29.3 3.8 9.3e-07 28.5 3.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR65651.1 - 3.2e-06 26.1 1.3 5.5e-06 25.3 1.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EMR65651.1 - 5.2e-06 25.9 0.1 9.4e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMR65651.1 - 8.8e-06 25.0 0.1 1.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EMR65651.1 - 1.3e-05 24.6 0.7 2.4e-05 23.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR65651.1 - 0.00037 20.7 1.0 0.001 19.3 1.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR65651.1 - 0.001 18.2 1.9 0.0028 16.8 1.9 1.7 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EMR65651.1 - 0.0012 18.6 3.4 0.023 14.3 3.4 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR65651.1 - 0.004 16.1 0.6 0.0063 15.4 0.6 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EMR65651.1 - 0.0055 16.0 2.2 0.0099 15.2 2.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR65651.1 - 0.0058 15.9 0.7 0.012 14.9 0.7 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EMR65651.1 - 0.047 14.3 0.2 0.19 12.3 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PNKP_ligase PF16542.5 EMR65651.1 - 0.09 12.3 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain Raptor_N PF14538.6 EMR65652.1 - 3e-65 218.7 0.0 6.3e-65 217.6 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EMR65652.1 - 6.9e-06 26.7 0.7 17 6.5 0.0 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 EMR65652.1 - 0.0076 16.6 0.7 0.12 12.8 0.0 3.1 4 0 0 4 4 4 1 HEAT repeats BBS2_Mid PF14783.6 EMR65652.1 - 0.011 15.7 0.0 7.7 6.6 0.0 2.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 EMR65652.1 - 0.18 11.9 0.3 0.35 10.9 0.3 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 EMR65652.1 - 6.7 7.3 10.0 26 5.4 0.2 5.4 7 0 0 7 7 7 0 HEAT repeat Kelch_4 PF13418.6 EMR65653.1 - 2e-34 117.3 7.8 1e-06 28.6 0.5 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EMR65653.1 - 2.9e-29 100.5 13.0 9.9e-09 35.0 0.2 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 EMR65653.1 - 4.7e-29 99.7 7.3 2.9e-12 46.4 0.4 6.8 6 1 1 7 7 7 6 Kelch motif Kelch_1 PF01344.25 EMR65653.1 - 2.8e-28 97.2 6.0 9.5e-12 44.3 0.3 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 EMR65653.1 - 1.7e-27 95.1 11.8 2.8e-08 33.8 0.1 7.0 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EMR65653.1 - 7.3e-21 73.3 9.2 4.7e-08 32.7 0.2 6.7 6 1 0 6 6 6 5 Kelch motif Mga PF05043.13 EMR65653.1 - 0.24 12.0 2.1 3.2 8.4 0.1 3.2 3 0 0 3 3 3 0 Mga helix-turn-helix domain Amino_oxidase PF01593.24 EMR65654.1 - 6.2e-24 85.1 0.3 3.2e-22 79.4 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR65654.1 - 1e-13 51.3 0.2 2.4e-13 50.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR65654.1 - 1.5e-12 47.8 2.2 1.4e-11 44.6 2.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR65654.1 - 1.6e-07 30.9 1.3 3e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR65654.1 - 1e-05 24.5 0.8 0.0028 16.4 2.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMR65654.1 - 1.5e-05 24.3 4.9 0.00011 21.4 3.2 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EMR65654.1 - 0.001 18.5 6.6 0.023 14.0 5.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR65654.1 - 0.0025 17.1 2.5 0.0054 16.0 2.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR65654.1 - 0.01 15.1 0.6 0.02 14.1 0.6 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 EMR65654.1 - 0.014 14.7 0.6 0.033 13.4 0.7 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EMR65654.1 - 0.073 13.1 2.5 0.31 11.0 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 EMR65654.1 - 0.15 11.7 0.4 0.32 10.6 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SnoaL_2 PF12680.7 EMR65654.1 - 0.16 12.6 1.1 1.2 9.8 0.1 2.4 2 0 0 2 2 2 0 SnoaL-like domain GIDA PF01134.22 EMR65654.1 - 0.33 10.0 4.8 0.44 9.6 4.2 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EMR65654.1 - 0.41 11.2 4.8 11 6.7 1.9 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 EMR65654.1 - 0.75 9.2 2.4 1.2 8.6 2.4 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Lycopene_cycl PF05834.12 EMR65654.1 - 0.92 8.5 3.2 0.77 8.7 1.5 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein EAF PF09816.9 EMR65656.1 - 3.4e-23 81.9 0.3 7.1e-23 80.9 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor FYDLN_acid PF09538.10 EMR65656.1 - 3.7 8.3 42.0 0.43 11.3 7.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (FYDLN_acid) ORC6 PF05460.13 EMR65656.1 - 8.4 5.6 12.1 13 5.0 11.5 1.6 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TauD PF02668.16 EMR65657.1 - 3.2e-61 207.5 0.4 3.9e-61 207.2 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CBM_21 PF03370.13 EMR65658.1 - 3.8e-33 114.0 0.1 7.5e-33 113.1 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EMR65658.1 - 3.4e-09 37.2 0.2 7.1e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DUF4195 PF13836.6 EMR65658.1 - 0.19 11.8 5.3 0.63 10.1 5.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) Pkinase PF00069.25 EMR65659.1 - 3.1e-24 85.8 0.0 1.2e-12 47.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EMR65659.1 - 3.3e-07 29.9 0.0 0.005 16.1 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EMR65659.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Syja_N PF02383.18 EMR65660.1 - 1.2e-93 313.9 0.0 2.2e-93 313.1 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EMR65660.1 - 4.2e-37 126.4 0.0 1.4e-36 124.7 0.0 1.9 2 0 0 2 2 2 1 Inositol phosphatase p450 PF00067.22 EMR65661.1 - 8.2e-52 176.5 0.0 1.1e-51 176.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CsbD PF05532.12 EMR65662.1 - 1.5e-14 53.6 26.0 9.8e-10 38.2 5.6 3.4 2 2 1 3 3 3 3 CsbD-like CreD PF06123.12 EMR65662.1 - 0.017 14.0 1.9 0.02 13.7 1.9 1.0 1 0 0 1 1 1 0 Inner membrane protein CreD NSP2_assoc PF14758.6 EMR65662.1 - 0.028 14.8 2.2 0.032 14.6 1.8 1.4 1 1 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein DUF3292 PF11696.8 EMR65662.1 - 1.2 7.4 5.7 0.11 10.8 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) DUF3430 PF11912.8 EMR65663.1 - 0.0033 17.5 0.1 0.0036 17.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) VanZ PF04892.12 EMR65663.1 - 0.013 16.1 0.1 0.021 15.5 0.1 1.3 1 0 0 1 1 1 0 VanZ like family NAD_binding_10 PF13460.6 EMR65664.1 - 2e-09 37.6 0.0 4.7e-09 36.4 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMR65664.1 - 4.9e-07 29.5 0.0 2.3e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 EMR65664.1 - 7.9e-05 22.7 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EMR65664.1 - 0.011 15.9 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LpxI_N PF17930.1 EMR65664.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 LpxI N-terminal domain TrkA_N PF02254.18 EMR65664.1 - 0.16 12.2 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain N_BRCA1_IG PF16158.5 EMR65665.1 - 7.6e-36 122.9 0.2 3.7e-35 120.7 0.0 2.4 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EMR65665.1 - 1.6e-16 59.9 62.5 1.4e-05 24.8 4.2 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type PC4 PF02229.16 EMR65666.1 - 2.4e-21 75.1 0.0 4e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) YqfQ PF14181.6 EMR65666.1 - 1.5 9.0 10.5 0.18 12.0 1.4 2.1 2 0 0 2 2 2 0 YqfQ-like protein Coilin_N PF15862.5 EMR65666.1 - 2.9 7.7 8.9 1.1 9.1 0.6 2.1 2 0 0 2 2 2 0 Coilin N-terminus YqzE PF14038.6 EMR65667.1 - 1.9 8.6 3.9 5.1 7.2 3.9 1.7 1 0 0 1 1 1 0 YqzE-like protein TcfC PF16967.5 EMR65668.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 E-set like domain AhpC-TSA_2 PF13911.6 EMR65669.1 - 6.1e-15 55.3 0.0 1.4e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EMR65669.1 - 0.0013 18.6 0.0 0.0033 17.4 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMR65669.1 - 0.027 14.2 0.0 0.062 13.0 0.0 1.6 1 1 0 1 1 1 0 Redoxin Clat_adaptor_s PF01217.20 EMR65670.1 - 1.6e-51 174.0 1.2 1.9e-51 173.8 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EMR65670.1 - 0.031 15.0 0.1 0.053 14.3 0.1 1.5 1 0 0 1 1 1 0 Pullulanase N1-terminal domain CDC50 PF03381.15 EMR65671.1 - 6.1e-90 301.5 0.0 7.5e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SET PF00856.28 EMR65672.1 - 2.4e-16 60.6 0.0 4.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 SET domain Mucin PF01456.17 EMR65672.1 - 0.17 11.8 17.1 2.1 8.3 9.8 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3446 PF11928.8 EMR65672.1 - 0.52 10.6 7.9 4.1 7.8 3.1 2.6 3 0 0 3 3 3 0 Early growth response N-terminal domain AAA_12 PF13087.6 EMR65673.1 - 3e-59 200.0 0.0 5.5e-59 199.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.10 EMR65673.1 - 3.5e-56 189.4 0.0 5.2e-55 185.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 EMR65673.1 - 6.7e-53 180.1 2.7 5.2e-30 105.1 0.1 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EMR65673.1 - 2e-33 114.4 0.0 3.9e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EMR65673.1 - 5.3e-14 52.4 0.1 7.6e-13 48.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR65673.1 - 2.4e-09 37.7 2.9 2.7e-09 37.5 0.1 2.5 3 1 0 3 3 2 1 AAA domain ResIII PF04851.15 EMR65673.1 - 7.8e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EMR65673.1 - 9.9e-05 22.3 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EMR65673.1 - 0.00031 20.5 0.1 1.7 8.3 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 EMR65673.1 - 0.001 18.3 0.0 0.3 10.2 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 EMR65673.1 - 0.0021 17.6 0.0 0.082 12.4 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 EMR65673.1 - 0.0021 17.3 0.1 0.024 13.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 EMR65673.1 - 0.0052 16.6 0.1 0.0092 15.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 EMR65673.1 - 0.022 14.1 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 EMR65673.1 - 0.023 15.0 0.0 0.068 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EMR65673.1 - 0.027 13.4 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 EMR65673.1 - 0.038 13.6 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 EMR65673.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 EMR65673.1 - 0.19 11.2 0.0 0.53 9.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Asp PF00026.23 EMR65674.1 - 1.9e-68 231.2 2.2 2.5e-68 230.8 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR65674.1 - 3.6e-18 66.4 3.7 9.2e-14 52.1 3.7 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMR65674.1 - 5.7e-05 23.7 0.5 0.59 10.8 0.2 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EMR65674.1 - 0.0077 16.8 0.3 3.8 8.1 0.0 2.7 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease CMD PF02627.20 EMR65675.1 - 4.4e-10 39.5 1.1 1.4e-09 37.9 0.2 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family ATP-synt_C PF00137.21 EMR65676.1 - 1.4e-34 118.2 34.4 7.3e-22 77.5 14.8 2.2 2 0 0 2 2 2 2 ATP synthase subunit C PT PF04886.12 EMR65677.1 - 0.00011 21.6 61.5 0.0023 17.5 7.2 6.0 3 2 1 4 4 4 3 PT repeat P68HR PF08061.11 EMR65677.1 - 1.6 8.9 12.2 9.7 6.4 0.1 5.7 4 3 3 7 7 7 0 P68HR (NUC004) repeat Brix PF04427.18 EMR65678.1 - 6.1e-22 78.7 0.0 1.7e-21 77.2 0.0 1.6 1 1 0 1 1 1 1 Brix domain MFS_1 PF07690.16 EMR65679.1 - 6.2e-27 94.4 22.3 7e-22 77.8 7.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR65679.1 - 3.6e-07 29.1 9.3 3.6e-07 29.1 9.3 1.5 2 0 0 2 2 2 1 MFS/sugar transport protein Vps55 PF04133.14 EMR65679.1 - 0.26 11.2 4.6 0.87 9.6 0.4 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting 55 LacY_symp PF01306.19 EMR65679.1 - 0.45 9.2 11.4 0.74 8.5 0.2 2.2 2 0 0 2 2 2 0 LacY proton/sugar symporter DUF5308 PF17233.2 EMR65680.1 - 2.1e-61 207.0 13.2 1e-60 204.8 13.2 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF5308) DUF4628 PF15429.6 EMR65680.1 - 0.17 11.6 6.0 0.24 11.0 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) GREB1 PF15782.5 EMR65680.1 - 0.28 8.3 1.6 0.33 8.0 1.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Di19_C PF14571.6 EMR65680.1 - 0.35 11.4 3.1 3 8.4 0.0 2.3 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal Smg8_Smg9 PF10220.9 EMR65680.1 - 6.5 4.9 6.3 8.4 4.6 6.3 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Maf1 PF09174.10 EMR65681.1 - 1e-58 198.4 0.0 1.4e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator TPR_2 PF07719.17 EMR65682.1 - 9.8e-40 131.5 16.3 9.2e-05 22.3 0.0 10.9 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 EMR65682.1 - 6.8e-39 130.1 17.6 2.4e-05 23.9 0.0 11.5 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 EMR65682.1 - 6e-25 87.6 9.8 3.3e-05 24.4 0.2 7.2 7 1 0 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EMR65682.1 - 2.3e-22 78.4 13.0 0.0002 20.9 0.0 8.8 6 1 2 8 8 8 5 TPR repeat TPR_8 PF13181.6 EMR65682.1 - 1.7e-21 74.5 13.9 0.13 12.6 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 EMR65682.1 - 1.9e-19 68.6 5.6 0.00015 21.9 0.0 8.7 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMR65682.1 - 2.7e-16 59.8 14.4 0.00022 21.6 0.8 6.7 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMR65682.1 - 1.2e-14 54.4 27.2 0.0008 19.7 0.2 8.3 4 3 6 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 EMR65682.1 - 1.3e-14 54.1 14.3 4e-06 26.9 0.5 6.2 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMR65682.1 - 6e-14 51.6 17.0 0.017 15.9 0.8 8.6 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 EMR65682.1 - 1.7e-12 46.4 18.5 0.0081 16.1 0.1 8.6 7 1 1 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR65682.1 - 2e-08 34.3 9.4 0.055 13.7 0.2 5.4 2 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EMR65682.1 - 4.8e-08 32.8 4.8 3.8e-07 29.8 1.2 2.6 1 1 1 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 EMR65682.1 - 5.4e-08 32.5 27.3 0.041 13.7 0.7 8.4 10 0 0 10 10 7 3 Tetratricopeptide repeat MAS20 PF02064.15 EMR65682.1 - 1.6e-05 25.0 7.2 0.018 15.1 0.2 4.6 4 1 1 5 5 4 1 MAS20 protein import receptor SHNi-TPR PF10516.9 EMR65682.1 - 6.3e-05 22.3 12.8 0.23 11.0 0.0 6.5 7 0 0 7 7 7 2 SHNi-TPR NARP1 PF12569.8 EMR65682.1 - 8.8e-05 21.6 20.8 0.03 13.3 0.6 5.3 3 1 3 6 6 6 3 NMDA receptor-regulated protein 1 HrpB1_HrpK PF09613.10 EMR65682.1 - 0.00021 21.0 0.6 0.0043 16.7 0.7 2.6 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 EMR65682.1 - 0.00051 20.5 7.0 1.5 9.2 0.0 4.9 3 2 2 5 5 5 1 Bacterial transcriptional activator domain preATP-grasp_3 PF18301.1 EMR65682.1 - 0.00059 20.1 0.1 0.0052 17.0 0.1 2.4 2 0 0 2 2 2 1 pre ATP-grasp 3 domain TPR_6 PF13174.6 EMR65682.1 - 0.00062 20.2 20.8 4.9 8.0 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF3856 PF12968.7 EMR65682.1 - 0.00065 19.8 9.5 5.5 7.1 0.0 5.8 4 1 3 7 7 7 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 EMR65682.1 - 0.0026 18.4 0.9 1.9 9.3 0.1 4.0 3 0 0 3 3 2 1 Sel1 repeat PknG_TPR PF16918.5 EMR65682.1 - 0.007 15.1 1.2 0.037 12.8 0.1 2.5 2 1 1 3 3 3 1 Protein kinase G tetratricopeptide repeat TAF1_subA PF14929.6 EMR65682.1 - 0.028 13.8 0.7 0.3 10.5 0.7 2.3 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A ANAPC5 PF12862.7 EMR65682.1 - 0.066 13.3 6.6 16 5.6 0.3 4.1 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 EMR65682.1 - 0.077 13.1 14.3 12 6.0 0.1 6.4 7 0 0 7 7 5 0 MIT (microtubule interacting and transport) domain SPO22 PF08631.10 EMR65682.1 - 0.085 12.3 2.1 3.7 6.9 0.0 3.7 5 0 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like GAPT PF11770.8 EMR65682.1 - 0.15 12.0 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) TPR_21 PF09976.9 EMR65682.1 - 0.18 11.5 11.7 2.4 7.8 0.0 4.7 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 EMR65682.1 - 0.18 12.1 7.9 0.24 11.7 0.4 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR65682.1 - 1.5 9.6 9.5 45 5.1 0.0 4.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4810 PF16068.5 EMR65682.1 - 2.8 8.6 6.8 31 5.2 0.0 4.4 4 1 1 5 5 3 0 Domain of unknown function (DUF4810) Syntaxin PF00804.25 EMR65683.1 - 2.9e-23 82.6 5.1 3.7e-23 82.2 5.1 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EMR65683.1 - 6.9e-11 42.0 0.7 2.3e-10 40.3 0.7 2.0 1 0 0 1 1 1 1 SNARE domain DUF2207 PF09972.9 EMR65683.1 - 0.0032 16.3 0.6 0.0074 15.1 0.1 1.7 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) Syntaxin_2 PF14523.6 EMR65683.1 - 0.0046 17.3 4.3 0.0047 17.3 0.8 2.2 2 0 0 2 2 2 1 Syntaxin-like protein RIFIN PF02009.16 EMR65683.1 - 0.031 14.2 2.1 0.057 13.3 2.0 1.3 1 1 0 1 1 1 0 Rifin Peptidase_S46 PF10459.9 EMR65683.1 - 0.1 11.2 7.9 0.13 10.9 7.9 1.1 1 0 0 1 1 1 0 Peptidase S46 Phage_holin_3_6 PF07332.11 EMR65683.1 - 0.12 12.4 1.5 0.28 11.2 1.5 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Orf78 PF06024.12 EMR65683.1 - 0.15 12.4 0.4 0.39 11.0 0.4 1.8 1 0 0 1 1 1 0 Orf78 (ac78) Tweety PF04906.13 EMR65683.1 - 0.19 10.4 2.7 0.11 11.1 0.9 1.5 2 0 0 2 2 2 0 Tweety T2SSF PF00482.23 EMR65683.1 - 0.23 11.4 2.3 1 9.3 0.2 2.5 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Use1 PF09753.9 EMR65683.1 - 0.25 11.1 6.2 0.55 9.9 6.2 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 Mito_fiss_reg PF05308.11 EMR65683.1 - 0.3 11.2 4.8 0.43 10.6 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator SHNi-TPR PF10516.9 EMR65685.1 - 2.2e-14 52.6 0.3 2.2e-14 52.6 0.3 2.8 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 EMR65685.1 - 1.3e-05 25.4 6.7 0.00025 21.3 0.6 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR65685.1 - 0.0013 19.3 4.9 0.011 16.4 0.7 3.8 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 EMR65685.1 - 0.0016 18.4 3.0 0.0016 18.4 3.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR65685.1 - 0.0021 18.2 2.0 0.43 10.8 1.1 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EMR65685.1 - 0.0052 16.8 14.1 0.06 13.5 1.7 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF3856 PF12968.7 EMR65685.1 - 0.0064 16.6 3.4 0.21 11.7 0.2 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EMR65685.1 - 0.019 14.8 6.1 0.69 9.9 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMR65685.1 - 0.051 14.1 0.5 0.051 14.1 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMR65685.1 - 0.068 13.6 1.2 4.2 8.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMR65685.1 - 0.24 11.7 10.6 0.98 9.8 1.9 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMR65685.1 - 0.47 10.6 4.8 4.9 7.4 0.2 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMR65685.1 - 0.63 9.8 11.1 1.2 8.8 2.5 4.1 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.28 EMR65685.1 - 1.3 9.0 8.5 0.56 10.1 1.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat BRCT_2 PF16589.5 EMR65686.1 - 1.3e-07 31.9 0.0 2.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EMR65686.1 - 2e-05 24.4 1.3 0.00019 21.3 1.3 2.2 1 1 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 EMR65686.1 - 0.021 15.1 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DUF3682 PF12446.8 EMR65686.1 - 7.3 7.1 13.5 0.82 10.2 7.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) MFS_1 PF07690.16 EMR65687.1 - 1.2e-25 90.2 18.1 7.3e-17 61.3 9.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMR65687.1 - 0.0055 15.1 5.9 0.0062 14.9 0.3 2.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family FUSC_2 PF13515.6 EMR65688.1 - 1.2e-28 99.8 7.0 1.2e-28 99.8 7.0 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 EMR65688.1 - 9.6e-07 27.7 10.6 9.2e-05 21.2 9.2 2.8 2 1 0 2 2 2 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 EMR65688.1 - 1.6e-06 28.2 1.8 0.00042 20.2 0.1 2.3 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 ALMT PF11744.8 EMR65688.1 - 1.2e-05 24.4 11.3 0.0049 15.8 3.2 3.4 3 0 0 3 3 3 3 Aluminium activated malate transporter ArAE_2_N PF10337.9 EMR65688.1 - 0.00012 21.3 0.7 0.00012 21.3 0.7 3.2 3 1 1 4 4 4 1 Putative ER transporter, 6TM, N-terminal FUSC-like PF12805.7 EMR65688.1 - 0.26 10.3 3.3 3.3 6.7 0.1 3.3 2 1 0 3 3 3 0 FUSC-like inner membrane protein yccS Aldo_ket_red PF00248.21 EMR65689.1 - 3.1e-09 36.4 0.0 4.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1987 PF09345.10 EMR65689.1 - 0.21 11.3 0.1 1.2 8.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) Response_reg PF00072.24 EMR65690.1 - 2.1e-28 98.7 0.3 3.6e-28 98.0 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EMR65690.1 - 1.4e-11 44.8 0.7 2.3e-11 44.2 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L7Ae PF01248.26 EMR65691.1 - 6.5e-27 93.1 0.1 8.2e-27 92.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EMR65691.1 - 0.00031 20.8 0.1 0.00036 20.6 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EMR65691.1 - 0.0022 17.9 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Pectate_lyase PF03211.13 EMR65692.1 - 1.5e-84 282.6 7.5 1.8e-84 282.4 7.5 1.0 1 0 0 1 1 1 1 Pectate lyase Transketolase_N PF00456.21 EMR65693.1 - 3.3e-155 516.1 0.0 4.6e-155 515.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EMR65693.1 - 1.7e-47 161.4 0.0 4e-47 160.2 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMR65693.1 - 4.3e-13 49.2 0.0 8.9e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EMR65693.1 - 0.00013 21.2 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 EMR65693.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase RRP7 PF12923.7 EMR65694.1 - 1.2e-31 109.3 11.9 1.2e-31 109.3 11.9 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EMR65694.1 - 2.7e-19 69.5 0.1 5.5e-19 68.5 0.0 1.5 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain Usp PF00582.26 EMR65694.1 - 0.35 11.4 6.1 0.59 10.6 0.5 2.3 2 0 0 2 2 2 0 Universal stress protein family MTBP_N PF14918.6 EMR65694.1 - 0.65 9.4 3.0 0.21 11.0 0.2 1.5 2 0 0 2 2 2 0 MDM2-binding DUF3464 PF11947.8 EMR65694.1 - 6.4 6.5 6.3 0.9 9.3 0.4 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Aminotran_5 PF00266.19 EMR65695.1 - 8.6e-93 311.2 0.0 1.1e-92 310.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMR65695.1 - 4.4e-06 26.2 0.1 7.3e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMR65695.1 - 0.0001 21.7 0.0 0.00042 19.7 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.19 EMR65695.1 - 0.064 13.3 0.2 0.29 11.2 0.0 2.1 3 0 0 3 3 3 0 B12 binding domain Pyridoxal_deC PF00282.19 EMR65695.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Pro-kuma_activ PF09286.11 EMR65696.1 - 1.2e-38 132.6 0.0 2.5e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMR65696.1 - 0.001 18.4 0.1 0.0019 17.5 0.1 1.4 1 1 0 1 1 1 1 Subtilase family COPIIcoated_ERV PF07970.12 EMR65698.1 - 4.1e-36 124.9 0.0 5.6e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EMR65698.1 - 2.1e-24 85.7 0.0 3.8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sdh_cyt PF01127.22 EMR65699.1 - 0.82 9.7 10.0 0.82 9.7 0.1 3.3 2 1 1 4 4 4 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Methyltransf_34 PF11312.8 EMR65700.1 - 4.8e-94 315.0 0.0 2.9e-76 256.7 0.0 3.1 2 1 0 2 2 2 2 Putative SAM-dependent methyltransferase Spt5_N PF11942.8 EMR65700.1 - 0.003 18.5 5.6 0.003 18.5 5.6 4.0 4 1 0 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal Fructosamin_kin PF03881.14 EMR65701.1 - 1.3e-13 50.8 0.0 2.8e-13 49.8 0.0 1.4 1 1 1 2 2 2 1 Fructosamine kinase APH PF01636.23 EMR65702.1 - 9.5e-08 32.2 2.3 0.00056 19.9 0.8 3.1 2 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EMR65702.1 - 6.8e-07 28.8 0.0 0.0025 17.2 0.0 3.1 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EMR65702.1 - 2.1e-05 24.0 0.0 8.2e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR65702.1 - 0.002 17.4 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EMR65702.1 - 0.022 14.3 0.0 3.7 7.1 0.0 2.4 2 0 0 2 2 2 0 RIO1 family A_deaminase PF00962.22 EMR65703.1 - 1e-23 84.2 0.0 2e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase Btz PF09405.10 EMR65704.1 - 5.7e-20 71.9 1.3 5.7e-20 71.9 1.3 2.1 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding DUF4805 PF16063.5 EMR65704.1 - 0.043 13.1 1.8 0.059 12.7 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Gln-synt_C PF00120.24 EMR65705.1 - 4.8e-15 55.4 0.0 7.5e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EMR65705.1 - 3.2e-11 42.8 0.0 5.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Hydantoinase_B PF02538.14 EMR65706.1 - 7.1e-218 724.2 0.1 1e-217 723.6 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMR65706.1 - 3e-101 338.5 1.0 6.1e-101 337.5 1.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMR65706.1 - 1.1e-58 197.8 0.3 9.5e-57 191.6 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MOSC PF03473.17 EMR65707.1 - 5.8e-25 87.8 0.0 1.8e-24 86.2 0.0 1.9 2 0 0 2 2 2 1 MOSC domain Fer2 PF00111.27 EMR65707.1 - 5.4e-11 42.3 1.0 1.4e-10 41.0 1.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EMR65707.1 - 6.7e-07 29.9 0.4 3.5e-06 27.6 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.14 EMR65707.1 - 1.4e-06 28.0 0.0 3.6e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 3-alpha domain NAD_binding_6 PF08030.12 EMR65707.1 - 0.052 13.7 0.0 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Taxilin PF09728.9 EMR65708.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Myosin-like coiled-coil protein BAR PF03114.18 EMR65709.1 - 6.7e-67 225.6 6.5 8.3e-67 225.3 6.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EMR65709.1 - 2.8e-15 55.6 0.0 5.2e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMR65709.1 - 8.6e-14 51.1 0.0 1.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMR65709.1 - 1.7e-08 34.0 0.0 5.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ku_PK_bind PF08785.11 EMR65709.1 - 0.22 11.7 3.5 0.21 11.7 1.1 2.1 1 1 1 2 2 2 0 Ku C terminal domain like Topoisom_I_N PF02919.15 EMR65709.1 - 1.8 8.0 8.8 0.06 12.8 2.7 1.6 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment TMPIT PF07851.13 EMR65709.1 - 2.1 7.5 5.4 9.3 5.4 0.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein TMF_DNA_bd PF12329.8 EMR65709.1 - 6.9 6.8 10.7 0.41 10.7 5.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding p450 PF00067.22 EMR65710.1 - 2.8e-47 161.5 0.0 2.5e-46 158.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 FeS_assembly_P PF01883.19 EMR65710.1 - 0.13 12.5 0.4 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein Yae1_N PF09811.9 EMR65711.1 - 1.3e-06 28.0 8.6 2.6e-06 27.0 7.7 1.9 1 1 0 1 1 1 1 Essential protein Yae1, N terminal HD PF01966.22 EMR65712.1 - 2e-08 34.5 0.0 4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 HD domain DWNN PF08783.11 EMR65714.1 - 3.6e-31 107.3 0.1 6.2e-31 106.5 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EMR65714.1 - 5.9e-10 38.8 8.1 1.5e-09 37.5 7.4 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EMR65714.1 - 0.00038 20.4 1.0 0.00073 19.5 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle FYVE_2 PF02318.16 EMR65714.1 - 0.0051 17.0 2.4 0.0072 16.5 0.8 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4_2 PF13923.6 EMR65714.1 - 0.016 15.0 9.1 0.016 15.0 9.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EMR65714.1 - 0.017 15.0 2.1 0.032 14.1 2.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 EMR65714.1 - 0.026 14.7 0.7 0.096 12.9 0.0 2.4 2 0 0 2 2 2 0 U-box domain zf-CCHC_3 PF13917.6 EMR65714.1 - 0.026 14.5 0.5 0.071 13.1 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-RING_2 PF13639.6 EMR65714.1 - 0.11 12.8 6.5 0.24 11.8 6.5 1.6 1 0 0 1 1 1 0 Ring finger domain zf-Nse PF11789.8 EMR65714.1 - 0.52 10.2 4.6 1.2 9.0 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EMR65714.1 - 0.84 9.8 9.1 2.7 8.2 9.1 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMR65714.1 - 0.99 9.4 12.6 0.13 12.2 6.9 2.1 2 0 0 2 2 2 0 zinc-RING finger domain HypA PF01155.19 EMR65714.1 - 1.3 9.0 5.0 3.1 7.9 2.6 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4 PF00097.25 EMR65714.1 - 1.6 8.7 9.5 3.3 7.7 9.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 EMR65714.1 - 5.7 7.1 10.7 0.93 9.6 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF3127 PF11325.8 EMR65715.1 - 0.052 13.8 0.1 16 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) Glyoxalase PF00903.25 EMR65718.1 - 2e-13 50.7 0.1 2.7e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMR65718.1 - 0.00063 20.5 0.0 0.0012 19.6 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Amidohydro_2 PF04909.14 EMR65719.1 - 3.6e-24 86.1 0.1 1.4e-23 84.2 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase SUR7 PF06687.12 EMR65720.1 - 2.6e-22 79.5 10.7 3.8e-22 79.0 10.7 1.3 1 0 0 1 1 1 1 SUR7/PalI family WBP-1 PF11669.8 EMR65720.1 - 0.029 15.0 1.4 0.04 14.6 0.0 2.0 2 1 0 2 2 2 0 WW domain-binding protein 1 Fig1 PF12351.8 EMR65720.1 - 8 6.3 12.6 11 5.9 12.6 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 UcrQ PF02939.16 EMR65721.1 - 5.2e-37 125.6 2.1 6.2e-37 125.4 2.1 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 EMR65722.1 - 2.3e-24 86.4 7.4 5.4e-24 85.2 7.4 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EMR65722.1 - 0.00068 18.8 3.6 0.00089 18.4 3.6 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial ArsA_ATPase PF02374.15 EMR65723.1 - 6.5e-108 360.5 0.0 7.7e-108 360.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EMR65723.1 - 2.2e-12 47.2 0.1 6.8e-10 39.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 EMR65723.1 - 6.1e-12 45.7 0.0 8.9e-12 45.2 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EMR65723.1 - 1.2e-06 28.2 0.3 2.5e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EMR65723.1 - 4.1e-05 23.1 0.2 0.00022 20.7 0.1 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EMR65723.1 - 4.7e-05 23.1 0.0 0.0017 18.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EMR65723.1 - 0.00015 21.3 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 EMR65723.1 - 0.032 14.6 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EMR65723.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EMR65723.1 - 0.12 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EMR65723.1 - 0.16 12.5 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AMPK1_CBM PF16561.5 EMR65724.1 - 9e-06 25.8 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 EMR65724.1 - 0.022 14.7 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 Starch binding domain NAD_Gly3P_dh_N PF01210.23 EMR65725.1 - 6.8e-46 156.1 0.2 1.6e-45 154.9 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EMR65725.1 - 2.1e-41 141.5 0.2 3.4e-41 140.9 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus HABP4_PAI-RBP1 PF04774.15 EMR65725.1 - 0.13 13.1 0.6 0.32 11.8 0.6 1.6 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family AIG2_2 PF13772.6 EMR65726.1 - 0.00018 21.8 0.0 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family DUF1467 PF07330.12 EMR65726.1 - 0.22 11.5 0.2 3.2 7.8 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1467) Acetyltransf_1 PF00583.25 EMR65727.1 - 8.6e-09 35.7 0.0 5.3e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR65727.1 - 3.6e-06 26.9 0.1 0.00027 20.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR65727.1 - 4.6e-06 27.0 0.0 8.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR65727.1 - 0.0004 20.5 0.1 0.0044 17.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR65727.1 - 0.0016 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Chlam_OMP PF01308.17 EMR65727.1 - 0.025 13.4 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Chlamydia major outer membrane protein hDGE_amylase PF14701.6 EMR65728.1 - 6.7e-179 595.6 0.0 8.6e-179 595.2 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EMR65728.1 - 2e-118 395.7 0.0 3.1e-118 395.1 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EMR65728.1 - 8.1e-88 294.3 0.0 5.3e-87 291.7 0.0 2.2 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EMR65728.1 - 1.5e-30 105.2 0.0 3.2e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme adh_short_C2 PF13561.6 EMR65730.1 - 4e-37 128.0 0.0 5.4e-30 104.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR65730.1 - 2.5e-31 108.7 0.1 4e-22 78.6 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR65730.1 - 0.00023 21.2 0.2 0.037 13.9 0.2 2.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMR65730.1 - 0.00064 19.2 0.0 0.00088 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EMR65731.1 - 2.9e-11 43.4 0.0 8.3e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR65731.1 - 0.00048 20.1 0.0 0.0018 18.2 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR65731.1 - 0.0027 17.2 0.0 0.0076 15.7 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EMR65731.1 - 0.053 14.0 0.0 0.33 11.4 0.0 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 EMR65732.1 - 6.2e-28 97.8 0.1 7e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 XAP5 PF04921.14 EMR65733.1 - 8e-87 291.2 0.2 3.2e-86 289.2 0.2 2.1 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF4083 PF13314.6 EMR65734.1 - 0.021 14.7 0.2 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Cu_amine_oxid PF01179.20 EMR65735.1 - 2.3e-127 425.3 0.0 1.6e-126 422.6 0.0 1.9 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EMR65735.1 - 3.8e-06 27.2 0.0 7.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EMR65735.1 - 6.3e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DAO PF01266.24 EMR65736.1 - 1.2e-43 150.1 1.8 1.3e-43 149.9 1.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR65736.1 - 0.00033 20.0 0.3 0.12 11.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR65736.1 - 0.0011 19.2 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMR65736.1 - 0.0048 16.9 0.3 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EMR65736.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 EMR65736.1 - 0.012 14.4 0.6 0.064 12.0 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 EMR65736.1 - 0.022 15.0 0.1 0.097 12.9 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EMR65736.1 - 0.049 13.9 0.4 0.72 10.1 1.3 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 EMR65736.1 - 0.054 12.3 5.8 0.6 8.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 EMR65736.1 - 0.088 12.5 1.1 0.21 11.2 1.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mqo PF06039.15 EMR65736.1 - 0.12 10.9 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 EMR65736.1 - 0.36 9.9 3.3 0.63 9.1 3.3 1.5 1 1 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EMR65736.1 - 0.43 9.6 2.2 0.36 9.8 0.1 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EMR65736.1 - 1.3 8.0 5.2 1.1 8.2 1.4 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EMR65736.1 - 4 6.7 6.5 0.25 10.6 0.5 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 EMR65737.1 - 2.7e-07 29.9 32.1 2.9e-06 26.4 32.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR65737.1 - 1.3e-05 25.0 8.9 1.3e-05 25.0 8.9 2.5 1 1 2 3 3 3 1 Ion channel regulatory protein UNC-93 Peptidase_U4 PF03419.13 EMR65737.1 - 0.0085 15.4 2.4 0.0085 15.4 2.4 2.3 2 1 1 3 3 3 1 Sporulation factor SpoIIGA Nucleoporin_FG PF13634.6 EMR65738.1 - 6.7e-09 36.5 80.0 9.3e-07 29.6 21.3 3.9 2 1 2 4 4 4 3 Nucleoporin FG repeat region Prominin PF05478.11 EMR65738.1 - 0.022 12.8 0.0 0.12 10.3 0.0 1.8 2 0 0 2 2 2 0 Prominin Fib_alpha PF08702.10 EMR65738.1 - 0.029 14.6 0.2 6.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EMR65738.1 - 0.066 13.3 0.2 7.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 EMR65738.1 - 0.11 12.5 0.6 14 5.8 0.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fungal_trans PF04082.18 EMR65739.1 - 7.3e-11 41.6 0.0 1.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AFT PF08731.11 EMR65740.1 - 0.00024 21.5 1.7 0.00061 20.2 1.7 1.6 1 0 0 1 1 1 1 Transcription factor AFT GAS PF13851.6 EMR65740.1 - 0.0017 17.8 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding FAR1 PF03101.15 EMR65740.1 - 0.029 15.1 1.7 0.057 14.1 1.7 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain PRIMA1 PF16101.5 EMR65740.1 - 8.5 6.4 12.0 28 4.8 12.0 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Methyltransf_10 PF05971.12 EMR65741.1 - 2.1e-57 194.8 0.0 3e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EMR65741.1 - 4e-07 29.7 0.0 6.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EMR65741.1 - 0.00048 19.6 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EMR65741.1 - 0.0058 17.3 0.0 0.015 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR65741.1 - 0.03 15.0 0.0 0.093 13.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EMR65741.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 EMR65741.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_31 PF13847.6 EMR65741.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TrmK PF04816.12 EMR65741.1 - 0.24 10.9 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase SOR_SNZ PF01680.17 EMR65743.1 - 4.7e-104 346.6 6.0 6.2e-104 346.2 6.0 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EMR65743.1 - 3.1e-08 33.2 10.5 2.8e-06 26.8 1.2 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EMR65743.1 - 0.00034 20.1 0.5 0.039 13.4 0.1 3.1 2 1 1 3 3 3 1 Histidine biosynthesis protein Dus PF01207.17 EMR65743.1 - 0.00041 19.5 0.1 0.62 9.1 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 EMR65743.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 EMR65743.1 - 0.007 15.6 0.3 0.13 11.4 0.1 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 EMR65743.1 - 0.044 12.9 0.2 0.32 10.1 0.0 2.2 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 EMR65743.1 - 5.1 6.4 11.3 0.6 9.4 2.6 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase Fip1 PF05182.13 EMR65744.1 - 1.3e-20 72.7 2.2 2.7e-20 71.6 2.2 1.6 1 0 0 1 1 1 1 Fip1 motif YL1 PF05764.13 EMR65744.1 - 1.1 9.4 7.4 1.2 9.2 7.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein GMC_oxred_C PF05199.13 EMR65746.1 - 1.6e-28 100.1 0.0 3.1e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR65746.1 - 1.8e-19 70.3 0.0 2.7e-18 66.4 0.0 2.5 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EMR65746.1 - 8.4e-05 21.9 0.0 0.00096 18.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR65746.1 - 0.0021 17.4 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR65746.1 - 0.011 16.0 0.3 0.011 16.0 0.3 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR65746.1 - 0.09 12.1 0.3 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMR65746.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EMR65746.1 - 0.19 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fig1 PF12351.8 EMR65747.1 - 6.9e-32 110.9 7.8 8.5e-32 110.6 7.8 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF898 PF05987.13 EMR65747.1 - 6.7e-05 22.1 4.5 7.1e-05 22.0 4.5 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF751 PF05421.11 EMR65747.1 - 0.059 14.1 0.1 0.059 14.1 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF751) SUR7 PF06687.12 EMR65747.1 - 6.9 6.2 11.6 4.6 6.8 10.0 1.5 1 1 0 1 1 1 0 SUR7/PalI family HMG_box PF00505.19 EMR65749.1 - 5.3e-25 87.6 0.8 7.4e-25 87.2 0.8 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR65749.1 - 3e-17 63.0 1.3 5e-17 62.3 1.3 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EMR65749.1 - 0.0017 18.9 0.8 0.0063 17.1 0.0 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 EMR65749.1 - 0.011 15.7 0.4 0.021 14.8 0.4 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 ADH_zinc_N PF00107.26 EMR65750.1 - 2.6e-27 95.4 1.7 4.8e-27 94.5 1.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR65750.1 - 7e-17 62.7 0.4 1.6e-16 61.6 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR65750.1 - 1.2e-11 44.5 0.0 4e-11 42.8 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EMR65750.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 EMR65750.1 - 0.002 17.5 0.3 0.0035 16.7 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 EMR65750.1 - 0.16 11.9 0.1 0.41 10.6 0.1 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase CENP-H PF05837.12 EMR65751.1 - 1.8e-35 121.8 2.7 2.1e-35 121.5 2.7 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) CCDC85 PF10226.9 EMR65751.1 - 0.023 14.4 0.4 0.028 14.1 0.4 1.2 1 0 0 1 1 1 0 CCDC85 family Trans_reg_C PF00486.28 EMR65751.1 - 0.033 14.3 0.1 0.25 11.5 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal TMCO5 PF14992.6 EMR65751.1 - 0.046 13.3 0.2 0.057 13.0 0.2 1.3 1 0 0 1 1 1 0 TMCO5 family ATG11 PF10377.9 EMR65752.1 - 4.5e-43 146.4 0.1 4.5e-43 146.4 0.1 3.4 3 0 0 3 3 3 1 Autophagy-related protein 11 Tropomyosin PF00261.20 EMR65752.1 - 0.0018 17.7 8.2 0.0018 17.7 8.2 7.0 6 1 2 9 9 9 1 Tropomyosin DtxR PF18357.1 EMR65752.1 - 0.079 12.6 0.4 0.18 11.5 0.4 1.6 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain EzrA PF06160.12 EMR65752.1 - 0.27 9.4 54.3 0.039 12.1 17.6 4.8 3 2 2 5 5 5 0 Septation ring formation regulator, EzrA APG17 PF04108.12 EMR65752.1 - 9.4 5.2 59.4 0.0049 16.0 8.6 5.3 3 3 1 4 4 4 0 Autophagy protein Apg17 AA_permease PF00324.21 EMR65753.1 - 1.8e-128 429.1 40.6 2.1e-128 429.0 40.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR65753.1 - 1.2e-29 103.4 46.3 1.6e-29 103.0 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease WSC PF01822.19 EMR65754.1 - 2.3e-12 47.0 8.1 2.3e-12 47.0 8.1 1.6 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 EMR65754.1 - 1.4e-06 27.6 5.3 1.4e-06 27.6 5.3 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 EMR65754.1 - 0.0028 17.8 0.4 0.0043 17.2 0.4 1.3 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.6 EMR65754.1 - 0.045 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Adeno_E3_CR2 PF02439.15 EMR65754.1 - 0.064 13.0 1.3 0.16 11.8 1.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PTP_tm PF18861.1 EMR65754.1 - 0.11 12.4 0.3 0.19 11.7 0.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Gram_pos_anchor PF00746.21 EMR65754.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Cu_bind_like PF02298.17 EMR65755.1 - 0.0011 18.9 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.20 EMR65755.1 - 0.068 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Glyco_hydro_47 PF01532.20 EMR65756.1 - 6.9e-184 612.0 0.0 9.4e-184 611.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CFEM PF05730.11 EMR65757.1 - 6.2e-06 26.2 2.4 6.2e-06 26.2 2.4 3.0 2 0 0 2 2 2 1 CFEM domain DUF445 PF04286.12 EMR65759.1 - 0.00029 20.8 7.3 0.0004 20.3 6.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF4449 PF14613.6 EMR65759.1 - 0.024 14.8 0.0 0.024 14.8 0.0 3.1 5 0 0 5 5 5 0 Protein of unknown function (DUF4449) DUF2267 PF10025.9 EMR65759.1 - 0.11 12.7 7.0 2.8 8.2 0.7 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) DUF4208 PF13907.6 EMR65759.1 - 0.15 12.5 4.4 6 7.4 0.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) CHORD PF04968.12 EMR65760.1 - 6 7.7 8.5 10 6.9 0.1 2.9 1 1 1 2 2 2 0 CHORD Abhydrolase_1 PF00561.20 EMR65761.1 - 2.5e-25 89.6 0.1 8.5e-25 87.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EMR65761.1 - 9.1e-23 79.6 0.1 2e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EMR65761.1 - 0.00011 21.6 0.0 0.0057 16.0 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EMR65761.1 - 0.0012 18.5 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Pet191_N PF10203.9 EMR65762.1 - 1.3e-27 95.9 4.1 1.7e-27 95.5 4.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EMR65762.1 - 0.44 10.6 5.4 2.8 8.0 0.3 2.6 2 1 1 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EMR65762.1 - 2.1 8.4 6.6 7.3 6.7 1.4 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_C107 PF17222.3 EMR65763.1 - 0.084 11.8 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 eIF-5a PF01287.20 EMR65765.1 - 6.2e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Myosin_head PF00063.21 EMR65766.1 - 7.7e-267 887.0 0.0 2.3e-266 885.4 0.0 1.9 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 EMR65766.1 - 1.4e-12 46.4 267.7 5.7e-11 41.0 42.0 6.8 2 2 2 4 4 4 3 Myosin tail Myosin_N PF02736.19 EMR65766.1 - 1.3e-06 28.1 0.0 3.7e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 EMR65766.1 - 0.00036 20.2 13.7 0.00077 19.1 12.7 9.8 2 2 7 9 9 9 4 Intermediate filament protein AAA_22 PF13401.6 EMR65766.1 - 0.085 13.1 0.0 0.085 13.1 0.0 4.8 4 0 0 4 4 4 0 AAA domain UDPG_MGDP_dh_N PF03721.14 EMR65766.1 - 0.15 11.6 1.6 0.42 10.2 1.6 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain bVLRF1 PF18826.1 EMR65767.1 - 1.2e-54 184.2 0.5 2.3e-54 183.3 0.5 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EMR65767.1 - 3.9e-06 27.0 0.0 8.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EMR65767.1 - 0.024 15.1 0.2 0.062 13.8 0.2 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 EMR65767.1 - 0.18 12.4 0.0 0.42 11.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Peptidase_C1_2 PF03051.15 EMR65768.1 - 3.4e-150 500.7 0.0 4e-150 500.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EMR65768.1 - 1.3e-07 32.0 0.4 0.00034 20.8 0.6 2.6 2 1 0 2 2 2 2 Papain family cysteine protease MFS_1 PF07690.16 EMR65769.1 - 2.4e-15 56.3 42.6 1.6e-08 33.9 10.2 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Tropomyosin_1 PF12718.7 EMR65770.1 - 0.018 15.2 2.4 0.018 15.2 2.4 2.1 2 0 0 2 2 2 0 Tropomyosin like Rootletin PF15035.6 EMR65770.1 - 0.025 14.6 2.0 0.048 13.7 2.0 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion zf-C3H1 PF10650.9 EMR65770.1 - 0.11 12.2 1.1 0.18 11.6 1.1 1.3 1 0 0 1 1 1 0 Putative zinc-finger domain DUF4201 PF13870.6 EMR65770.1 - 1.2 8.8 4.4 1.2 8.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4140 PF13600.6 EMR65770.1 - 1.6 9.2 7.1 20 5.7 0.0 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 EMR65770.1 - 6.8 5.5 7.3 10 4.9 2.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein HET PF06985.11 EMR65771.1 - 1.4e-09 38.4 0.0 3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NFACT-C PF11923.8 EMR65772.1 - 2.7e-39 133.3 0.4 2.7e-39 133.3 0.4 3.2 5 0 0 5 5 5 1 NFACT protein C-terminal domain FbpA PF05833.11 EMR65772.1 - 2.3e-33 115.6 7.2 2.3e-33 115.6 7.2 1.5 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EMR65772.1 - 1.4e-32 112.6 0.0 3.3e-32 111.4 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF371 PF04027.13 EMR65772.1 - 0.1 12.6 0.0 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF371) Ndc1_Nup PF09531.10 EMR65772.1 - 6.1 5.4 7.5 13 4.3 7.5 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_A4 PF01828.17 EMR65774.1 - 5.5e-36 124.0 5.3 7e-36 123.7 5.3 1.0 1 0 0 1 1 1 1 Peptidase A4 family p450 PF00067.22 EMR65777.1 - 2.8e-45 154.9 0.0 3.9e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4407 PF14362.6 EMR65778.1 - 0.037 13.4 0.1 0.042 13.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 EMR65778.1 - 0.17 12.3 3.8 0.25 11.8 3.8 1.3 1 1 0 1 1 1 0 Cell division protein ZapB Zn_clus PF00172.18 EMR65779.1 - 8.3e-08 32.2 8.4 1.7e-07 31.2 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.27 EMR65781.1 - 5.1e-47 159.5 0.0 7e-45 152.6 0.0 2.7 1 1 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EMR65781.1 - 1.1e-13 51.3 4.4 1.2e-13 51.2 0.8 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Sec66 PF09802.9 EMR65781.1 - 0.0054 16.3 0.0 0.56 9.8 0.2 2.3 2 0 0 2 2 2 2 Preprotein translocase subunit Sec66 DUF5321 PF17254.2 EMR65781.1 - 0.045 13.2 0.4 0.1 12.0 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5321) p450 PF00067.22 EMR65782.1 - 1.4e-30 106.5 0.0 1.9e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Med12 PF09497.10 EMR65784.1 - 3e-20 72.3 0.1 1.9e-19 69.7 0.1 2.3 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 SLAC1 PF03595.17 EMR65785.1 - 2.2e-85 286.8 37.2 2.6e-85 286.6 37.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel STAC2_u1 PF16664.5 EMR65786.1 - 0.0048 17.4 0.8 0.0053 17.2 0.8 1.1 1 0 0 1 1 1 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 XRCC4 PF06632.12 EMR65786.1 - 0.059 12.2 2.7 0.063 12.1 2.7 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 TFIIA PF03153.13 EMR65786.1 - 0.14 12.1 11.7 0.14 12.1 11.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 EMR65786.1 - 1.4 8.8 5.9 1.4 8.8 5.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Rrn6 PF10214.9 EMR65786.1 - 3.5 6.0 11.5 3.6 6.0 11.5 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 EMR65786.1 - 4.4 6.0 6.2 4.5 5.9 6.2 1.0 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 EMR65786.1 - 4.6 6.8 16.6 5.6 6.5 16.6 1.2 1 0 0 1 1 1 0 Spt20 family Baculo_PP31 PF05311.11 EMR65786.1 - 6 6.3 6.7 7.6 5.9 6.7 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) NUDE_C PF04880.13 EMR65787.1 - 1.6e-36 126.4 8.8 1.6e-36 126.4 8.8 2.3 2 1 0 2 2 2 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 EMR65787.1 - 0.0013 19.1 7.6 0.0013 19.1 7.6 4.0 1 1 1 2 2 1 1 Cell division protein ZapB ERM PF00769.19 EMR65787.1 - 0.0033 17.3 34.0 0.0074 16.1 10.8 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family DHR10 PF18595.1 EMR65787.1 - 0.004 17.2 16.1 0.004 17.2 16.1 3.0 1 1 2 3 3 3 2 Designed helical repeat protein 10 domain CLZ PF16526.5 EMR65787.1 - 0.034 14.5 5.0 0.034 14.5 5.0 3.6 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_13 PF13166.6 EMR65787.1 - 0.037 12.7 22.3 0.048 12.3 22.3 1.1 1 0 0 1 1 1 0 AAA domain Chibby PF14645.6 EMR65787.1 - 0.048 14.1 12.5 0.69 10.3 5.8 2.3 1 1 1 2 2 2 0 Chibby family Filament PF00038.21 EMR65787.1 - 0.053 13.1 31.1 0.21 11.1 31.1 1.9 1 1 0 1 1 1 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 EMR65787.1 - 0.055 13.5 34.3 0.31 11.1 14.5 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 EMR65787.1 - 0.21 12.0 28.0 0.37 11.2 10.9 2.4 1 1 1 2 2 2 0 Fez1 ADIP PF11559.8 EMR65787.1 - 0.23 11.5 27.6 0.11 12.6 11.9 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 EMR65787.1 - 0.24 11.6 30.3 1.6 8.9 30.6 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EMR65787.1 - 0.38 10.8 14.8 0.13 12.3 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 EMR65787.1 - 0.53 10.1 24.6 0.79 9.5 10.2 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 Tho2 PF11262.8 EMR65787.1 - 0.57 9.3 21.1 0.13 11.5 6.3 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 YabA PF06156.13 EMR65787.1 - 0.92 10.2 22.4 0.58 10.8 5.6 3.1 1 1 0 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 EMR65787.1 - 1.4 9.0 34.7 1.6 8.8 11.0 3.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YjbH PF06082.11 EMR65787.1 - 2.2 7.0 8.8 2.6 6.8 8.8 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH APG6_N PF17675.1 EMR65787.1 - 2.6 8.6 40.5 0.34 11.4 13.4 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region FPP PF05911.11 EMR65787.1 - 2.6 6.1 29.4 0.48 8.5 15.1 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Prefoldin_2 PF01920.20 EMR65787.1 - 3.5 7.6 31.5 0.57 10.2 7.1 4.7 1 1 4 5 5 5 0 Prefoldin subunit Tropomyosin_1 PF12718.7 EMR65787.1 - 4.2 7.5 37.0 8.3 6.6 23.7 3.1 1 1 1 2 2 2 0 Tropomyosin like DUF3450 PF11932.8 EMR65787.1 - 4.2 6.6 27.6 0.042 13.2 5.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 EMR65787.1 - 4.5 5.1 19.7 10 3.9 18.5 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 EMR65787.1 - 4.5 5.1 12.3 6.2 4.6 12.3 1.1 1 0 0 1 1 1 0 Prominin DMPK_coil PF08826.10 EMR65787.1 - 5.2 7.3 27.4 0.15 12.2 3.1 3.5 3 0 0 3 3 3 0 DMPK coiled coil domain like PRKG1_interact PF15898.5 EMR65787.1 - 7.1 7.6 29.5 1.4 9.8 9.9 3.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF16 PF01519.16 EMR65787.1 - 7.6 7.1 19.6 0.27 11.7 6.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 HIP1_clath_bdg PF16515.5 EMR65787.1 - 8.3 7.1 27.5 1.7 9.3 12.7 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fmp27_WPPW PF10359.9 EMR65787.1 - 9.6 4.9 21.1 86 1.8 21.1 2.2 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Peptidase_S8 PF00082.22 EMR65789.1 - 3.5e-38 131.6 0.0 1.1e-37 129.9 0.0 1.7 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EMR65789.1 - 7.3e-19 68.6 0.1 1.7e-18 67.4 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 EMR65789.1 - 7.3e-05 22.7 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 PA domain FlgD_ig PF13860.6 EMR65789.1 - 0.048 13.5 0.1 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain Inhibitor_I9 PF05922.16 EMR65789.1 - 0.063 13.9 0.1 0.22 12.2 0.1 1.9 1 1 0 1 1 1 0 Peptidase inhibitor I9 Methyltransf_2 PF00891.18 EMR65790.1 - 4.4e-22 78.4 0.0 6e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EMR65790.1 - 0.0038 17.2 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Dimerisation domain Sugar_tr PF00083.24 EMR65792.1 - 3.1e-49 168.1 30.4 4.8e-29 101.5 20.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR65792.1 - 6.1e-19 68.2 38.7 4.8e-15 55.3 11.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR65792.1 - 0.0027 16.2 6.5 0.004 15.6 5.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YesK PF14150.6 EMR65792.1 - 2.7 8.2 16.0 0.56 10.4 2.0 3.8 2 1 2 4 4 4 0 YesK-like protein LOH1CR12 PF10158.9 EMR65793.1 - 0.0072 16.3 0.5 0.012 15.7 0.5 1.2 1 0 0 1 1 1 1 Tumour suppressor protein TSC22 PF01166.18 EMR65793.1 - 0.014 15.6 0.5 0.035 14.4 0.3 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 EMR65793.1 - 0.11 13.2 0.3 0.19 12.4 0.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF572 PF04502.13 EMR65793.1 - 0.13 11.9 1.0 0.16 11.6 1.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ZapB PF06005.12 EMR65793.1 - 0.13 12.7 7.0 0.12 12.8 5.7 1.6 1 1 0 1 1 1 0 Cell division protein ZapB GIT_CC PF16559.5 EMR65793.1 - 1.5 8.8 5.4 12 5.8 0.7 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor MFS_1 PF07690.16 EMR65794.1 - 4.1e-54 183.8 36.6 4.1e-54 183.8 36.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65794.1 - 1.9e-16 60.0 7.8 1.9e-16 60.0 7.8 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EMR65794.1 - 1.9e-07 29.9 2.9 3.5e-07 29.0 2.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EMR65794.1 - 8.5e-05 21.1 5.1 0.00014 20.4 5.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector SR-25 PF10500.9 EMR65796.1 - 0.00032 20.4 15.3 0.00036 20.2 15.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Mlf1IP PF10248.9 EMR65796.1 - 0.0038 17.2 8.3 0.0043 17.0 8.3 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein FAM184 PF15665.5 EMR65796.1 - 0.052 13.3 5.6 0.065 13.0 5.6 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B MID_MedPIWI PF18296.1 EMR65796.1 - 0.058 13.2 5.2 0.061 13.1 5.2 1.0 1 0 0 1 1 1 0 MID domain of medPIWI Golgin_A5 PF09787.9 EMR65796.1 - 0.14 11.6 6.8 0.17 11.3 6.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 EMR65796.1 - 0.37 10.1 6.0 0.43 9.9 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC106 PF15794.5 EMR65796.1 - 0.78 9.4 12.3 0.96 9.1 12.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Menin PF05053.13 EMR65796.1 - 1.2 7.4 8.5 1.3 7.3 8.5 1.0 1 0 0 1 1 1 0 Menin SRP-alpha_N PF04086.13 EMR65796.1 - 2.2 8.1 12.5 3.1 7.6 12.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DDHD PF02862.17 EMR65796.1 - 4 7.5 9.2 5 7.2 9.2 1.0 1 0 0 1 1 1 0 DDHD domain Macoilin PF09726.9 EMR65796.1 - 4.3 5.8 12.1 4.9 5.6 12.1 1.0 1 0 0 1 1 1 0 Macoilin family AA_permease PF00324.21 EMR65798.1 - 2.1e-101 339.9 42.4 2.6e-101 339.6 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR65798.1 - 2.3e-18 66.3 43.6 2.9e-18 65.9 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-binding PF00249.31 EMR65799.1 - 3.1e-17 62.5 4.1 1.6e-06 28.2 0.6 4.0 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR65799.1 - 3.4e-15 56.0 3.4 2.9e-09 37.0 0.1 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EMR65799.1 - 0.0019 18.5 8.1 0.0021 18.4 0.6 3.3 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EMR65799.1 - 0.085 13.1 0.3 9 6.6 0.0 2.7 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Abhydrolase_1 PF00561.20 EMR65801.1 - 4.9e-08 32.9 0.0 4e-06 26.7 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR65801.1 - 0.0045 17.6 0.4 0.0073 16.9 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Drc1-Sld2 PF11719.8 EMR65803.1 - 3.4e-56 191.7 16.9 4.2e-56 191.4 16.9 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein TPR_12 PF13424.6 EMR65805.1 - 1.1e-09 38.5 5.2 0.00034 20.8 0.6 2.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMR65805.1 - 2e-06 27.4 1.0 0.0031 17.4 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMR65805.1 - 6.7e-06 25.8 7.5 0.0064 16.3 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMR65805.1 - 3.1e-05 23.8 2.9 0.11 12.7 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMR65805.1 - 0.00014 21.5 4.3 0.19 11.6 0.3 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR65805.1 - 0.00044 20.1 5.3 0.25 11.6 0.5 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMR65805.1 - 0.0035 18.0 2.1 1.9 9.5 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMR65805.1 - 0.078 13.7 0.1 1.9e+02 3.0 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Serine_protease PF18405.1 EMR65805.1 - 0.26 10.4 0.0 0.34 10.0 0.0 1.1 1 0 0 1 1 1 0 Gammaproteobacterial serine protease TPR_16 PF13432.6 EMR65805.1 - 1.4 9.7 5.5 36 5.1 1.5 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.17 EMR65806.1 - 4e-46 157.6 0.5 5.3e-46 157.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ECH_1 PF00378.20 EMR65807.1 - 2.6e-45 154.7 0.0 3.4e-34 118.3 0.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMR65807.1 - 1.4e-22 80.7 3.2 8.2e-12 45.3 0.9 3.0 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase DUF3439 PF11921.8 EMR65807.1 - 2.1 8.3 7.0 3.4 7.7 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) K_oxygenase PF13434.6 EMR65808.1 - 7.7e-12 45.0 0.0 2.9e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMR65808.1 - 1.5e-08 34.3 0.0 2.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR65808.1 - 1.9e-07 30.6 1.8 0.0035 16.7 0.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR65808.1 - 0.00046 19.9 1.1 2.7 7.5 0.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR65808.1 - 0.0021 17.2 0.4 0.062 12.3 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein DUF3246 PF11596.8 EMR65808.1 - 0.012 15.1 1.8 0.019 14.4 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) FAD_binding_3 PF01494.19 EMR65808.1 - 0.031 13.5 3.2 0.19 10.9 0.3 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EMR65808.1 - 0.034 12.8 0.1 3.5 6.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EMR65808.1 - 0.049 12.9 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EMR65808.1 - 0.099 13.2 3.0 4.2 8.0 0.1 2.8 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR65808.1 - 0.17 11.8 4.6 0.84 9.6 0.4 3.0 3 1 0 3 3 3 0 FAD-NAD(P)-binding DUF4611 PF15387.6 EMR65808.1 - 0.37 11.0 3.2 1.1 9.5 2.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EMR65808.1 - 7.7 5.7 6.0 14 4.9 6.0 1.3 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_3 PF07859.13 EMR65809.1 - 9.4e-40 136.7 0.2 2e-39 135.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR65809.1 - 6.9e-07 28.5 0.0 3.4e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 EMR65809.1 - 0.0023 17.5 0.0 0.0087 15.6 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EMR65809.1 - 0.004 16.7 0.0 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Eno-Rase_NADH_b PF12242.8 EMR65809.1 - 0.0092 15.7 0.0 0.59 9.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HTH_Tnp_Tc3_2 PF01498.18 EMR65809.1 - 0.13 12.5 2.9 4.1 7.7 0.2 2.3 2 0 0 2 2 2 0 Transposase AXE1 PF05448.12 EMR65809.1 - 0.18 10.4 0.1 0.3 9.7 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MSC PF09402.10 EMR65809.1 - 0.24 10.8 2.5 0.4 10.1 2.5 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF4834 PF16118.5 EMR65809.1 - 6.9 7.7 8.8 18 6.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2196 PF09962.9 EMR65810.1 - 5.7e-23 80.7 3.1 1e-22 79.8 3.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) TOBE_2 PF08402.10 EMR65810.1 - 0.062 13.5 0.8 0.16 12.2 0.5 1.9 2 0 0 2 2 2 0 TOBE domain HAS-barrel PF09378.10 EMR65810.1 - 0.15 12.2 0.5 0.91 9.7 0.5 2.0 1 1 0 1 1 1 0 HAS barrel domain Mac PF12464.8 EMR65811.1 - 4e-18 65.4 0.0 6.2e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 EMR65811.1 - 3.8e-12 45.4 11.3 9.3e-12 44.2 2.7 3.1 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMR65811.1 - 1.3e-11 44.0 5.3 8.3e-11 41.4 1.8 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Subtilosin_A PF11420.8 EMR65811.1 - 0.036 14.1 0.6 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Bacteriocin subtilosin A PWI PF01480.17 EMR65813.1 - 4.6e-14 52.5 0.8 4.6e-14 52.5 0.8 2.4 2 0 0 2 2 2 1 PWI domain Ribosomal_S21 PF01165.20 EMR65814.1 - 8.3e-15 54.2 2.6 8.3e-15 54.2 2.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 TPT PF03151.16 EMR65815.1 - 6e-18 65.2 17.1 7.4e-18 64.9 17.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EMR65815.1 - 0.074 12.2 14.6 0.58 9.3 14.6 2.1 1 1 0 1 1 1 0 UAA transporter family PMP1_2 PF08114.11 EMR65815.1 - 0.34 10.7 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 0 ATPase proteolipid family p450 PF00067.22 EMR65817.1 - 2.6e-09 36.3 0.0 2.8e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 EMR65819.1 - 0.0033 16.3 1.3 0.014 14.2 0.2 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Rnk_N PF14760.6 EMR65819.1 - 0.08 13.4 0.6 0.18 12.3 0.6 1.6 1 0 0 1 1 1 0 Rnk N-terminus Las1 PF04031.13 EMR65820.1 - 7.7e-62 207.9 1.2 1.5e-61 207.0 1.2 1.5 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 EMR65820.1 - 1.4e-21 76.8 0.2 3.4e-21 75.5 0.2 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EMR65820.1 - 2.2e-14 53.9 2.8 4.9e-12 46.3 2.8 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMR65820.1 - 0.01 15.4 0.1 0.031 13.8 0.1 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Cation_efflux PF01545.21 EMR65821.1 - 1.7e-09 37.7 11.4 2.7e-09 37.1 11.4 1.3 1 0 0 1 1 1 1 Cation efflux family stn_TNFRSF12A PF12191.8 EMR65821.1 - 0.41 10.9 3.2 3.7 7.8 0.2 3.1 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Sec10 PF07393.11 EMR65822.1 - 2.2e-158 528.9 0.0 2.7e-158 528.6 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF5302 PF17227.2 EMR65822.1 - 0.14 13.2 1.8 0.64 11.0 1.8 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5302) Abhydrolase_1 PF00561.20 EMR65823.1 - 7.9e-12 45.4 0.0 1.4e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR65823.1 - 2.3e-05 23.8 0.0 8.1e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Alpha-amylase_C PF02806.18 EMR65823.1 - 0.078 13.5 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain PIG-Y PF15159.6 EMR65824.1 - 8.9e-21 74.6 7.7 1.5e-20 73.8 7.7 1.4 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Mid1 PF12929.7 EMR65825.1 - 2.3e-146 488.4 0.1 2.7e-146 488.1 0.1 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EMR65825.1 - 0.00012 22.7 4.5 0.0028 18.2 1.1 2.4 2 0 0 2 2 2 2 Fz domain Cohesin_load PF10345.9 EMR65826.1 - 3.1e-89 300.1 2.3 3.9e-89 299.7 2.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor RAMP4 PF06624.12 EMR65827.1 - 2.3e-24 85.2 0.2 2.5e-24 85.1 0.2 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF5542 PF17696.1 EMR65827.1 - 0.015 15.4 0.2 0.024 14.8 0.2 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5542) SMAP PF15477.6 EMR65828.1 - 1.2e-13 51.8 4.7 1.2e-13 51.8 4.7 5.4 2 1 0 2 2 2 1 Small acidic protein family SpoIIE PF07228.12 EMR65829.1 - 4.3e-10 39.8 0.0 3.2e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EMR65829.1 - 1.1e-06 28.4 0.1 0.011 15.4 0.1 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EMR65829.1 - 8.7e-06 25.5 1.0 1.8e-05 24.5 0.7 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C GPI-anchored PF10342.9 EMR65830.1 - 3.6e-05 24.4 0.0 5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fer2_3 PF13085.6 EMR65831.1 - 6.9e-33 112.9 0.0 1.1e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EMR65831.1 - 3.8e-08 33.8 5.9 3.8e-08 33.8 5.9 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMR65831.1 - 2e-07 31.4 7.9 2e-07 31.4 7.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMR65831.1 - 3e-07 30.5 3.7 3e-07 30.5 3.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EMR65831.1 - 4.6e-05 23.9 1.7 4.6e-05 23.9 1.7 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EMR65831.1 - 0.0023 17.8 3.2 0.0032 17.4 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EMR65831.1 - 0.024 14.9 0.4 0.88 9.8 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMR65831.1 - 0.68 10.2 12.7 9.7 6.5 11.3 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain AMP-binding PF00501.28 EMR65833.1 - 1.2e-43 149.3 0.0 3.7e-32 111.4 0.0 2.1 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EMR65833.1 - 1.2e-16 61.4 0.1 3.1e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Arginase PF00491.21 EMR65834.1 - 2.8e-85 286.2 0.4 3.5e-85 285.9 0.4 1.1 1 0 0 1 1 1 1 Arginase family Abhydrolase_3 PF07859.13 EMR65835.1 - 0.00078 19.4 1.8 0.014 15.3 1.8 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR65835.1 - 0.0012 19.5 8.8 0.0037 17.9 8.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EMR65835.1 - 0.23 11.5 0.3 0.43 10.7 0.3 1.4 1 0 0 1 1 1 0 Thioesterase domain TauD PF02668.16 EMR65836.1 - 2.4e-53 181.6 1.6 2.8e-53 181.4 1.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_28 PF00295.17 EMR65837.1 - 2.1e-13 50.0 4.4 9.9e-13 47.8 4.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EMR65837.1 - 7.3e-11 42.3 8.4 2.9e-10 40.4 5.9 2.7 1 1 1 2 2 2 1 Pectate lyase superfamily protein Peptidase_S78_2 PF14550.6 EMR65837.1 - 0.52 10.4 2.5 37 4.4 0.1 3.3 3 1 1 4 4 4 0 Putative phage serine protease XkdF Beta_helix PF13229.6 EMR65837.1 - 0.54 10.1 4.0 1.2 9.0 0.5 2.6 2 2 0 2 2 2 0 Right handed beta helix region p450 PF00067.22 EMR65838.1 - 2.6e-21 75.9 0.0 6.4e-21 74.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_62 PF03664.13 EMR65839.1 - 1e-151 503.9 10.8 1.2e-151 503.6 10.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Aminotran_5 PF00266.19 EMR65840.1 - 3.8e-08 32.7 0.0 1.2e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMR65840.1 - 0.0027 17.1 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EMR65840.1 - 0.2 10.2 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Asp PF00026.23 EMR65842.1 - 2.2e-53 181.8 0.0 2.7e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR65842.1 - 2e-15 57.5 0.3 2.4e-14 54.0 0.3 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMR65842.1 - 0.0057 17.3 1.1 0.35 11.5 0.1 3.0 4 0 0 4 4 4 1 Aspartyl protease gag-asp_proteas PF13975.6 EMR65842.1 - 0.088 13.4 0.2 0.65 10.6 0.2 2.4 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease OPT PF03169.15 EMR65843.1 - 1.2e-66 225.7 42.9 5.1e-55 187.3 29.6 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein PetL PF05115.14 EMR65843.1 - 0.018 15.0 0.2 0.018 15.0 0.2 4.3 4 0 0 4 4 4 0 Cytochrome B6-F complex subunit VI (PetL) EssA PF10661.9 EMR65843.1 - 0.22 11.3 0.0 0.5 10.2 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA NmrA PF05368.13 EMR65844.1 - 1.6e-15 57.3 0.0 2.2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR65844.1 - 1.8e-14 54.0 0.9 6.4e-14 52.3 0.4 1.9 1 1 1 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EMR65844.1 - 1.3e-06 28.8 0.7 3.5e-06 27.4 0.2 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EMR65844.1 - 4.8e-05 23.5 0.1 0.00025 21.2 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 EMR65844.1 - 0.00026 21.5 1.2 0.0029 18.2 0.4 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMR65844.1 - 0.0022 18.1 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EMR65844.1 - 0.0023 17.4 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMR65844.1 - 0.022 13.9 0.1 0.087 12.0 0.0 2.0 3 0 0 3 3 3 0 Male sterility protein NAD_binding_8 PF13450.6 EMR65845.1 - 2.2e-08 34.2 0.5 5.2e-08 33.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR65845.1 - 2.2e-06 27.1 0.0 4.9e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR65845.1 - 2.2e-05 23.9 2.1 0.00011 21.5 2.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR65845.1 - 0.00014 21.6 5.0 0.00028 20.6 4.5 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR65845.1 - 0.0011 19.4 1.5 0.0011 19.4 1.5 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR65845.1 - 0.0025 17.2 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR65845.1 - 0.0054 15.9 3.8 0.016 14.3 3.4 1.8 1 1 1 2 2 2 1 FAD binding domain Rossmann-like PF10727.9 EMR65845.1 - 0.026 14.4 0.6 0.061 13.2 0.6 1.6 1 0 0 1 1 1 0 Rossmann-like domain GIDA PF01134.22 EMR65845.1 - 0.043 12.9 2.1 0.062 12.4 2.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 EMR65845.1 - 0.069 12.4 0.3 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EMR65845.1 - 0.26 9.9 2.2 0.38 9.4 2.2 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 EMR65845.1 - 3.6 7.4 6.5 0.3 10.9 1.9 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 EMR65846.1 - 2.8e-33 115.3 4.3 1.8e-27 96.4 0.0 3.0 2 1 1 3 3 3 2 KR domain ADH_zinc_N_2 PF13602.6 EMR65846.1 - 3.6e-20 73.4 0.0 1.9e-18 67.8 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EMR65846.1 - 5.1e-18 65.6 0.0 1.7e-17 63.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EMR65846.1 - 1.2e-17 64.1 0.0 3.6e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 EMR65846.1 - 3.2e-11 43.3 0.0 1.8e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR65846.1 - 2.3e-10 40.5 0.0 5.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR65846.1 - 3.4e-10 40.5 0.0 1.4e-08 35.3 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR65846.1 - 8.2e-09 36.0 0.0 4.8e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EMR65846.1 - 6.4e-06 26.4 0.0 1.5e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EMR65846.1 - 3.1e-05 23.8 0.3 0.00042 20.2 0.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 EMR65846.1 - 0.00043 19.7 0.0 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 EMR65846.1 - 0.00052 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 EMR65846.1 - 0.00053 19.8 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_28 PF02636.17 EMR65846.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 EMR65846.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain APH PF01636.23 EMR65848.1 - 1.6e-18 67.6 0.0 3.6e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMR65848.1 - 0.0065 16.1 0.2 0.3 10.7 0.1 2.3 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EMR65848.1 - 0.026 14.1 0.2 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase EcKinase PF02958.20 EMR65848.1 - 0.042 13.1 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.16 EMR65849.1 - 2.1e-09 36.8 9.5 2.6e-09 36.5 9.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65849.1 - 4.1e-06 25.9 5.2 4.1e-06 25.9 5.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EMR65849.1 - 0.00075 18.0 0.6 0.00092 17.7 0.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glycos_transf_1 PF00534.20 EMR65849.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 PX PF00787.24 EMR65850.1 - 1.9e-17 63.3 0.0 3.2e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 PX domain F-box PF00646.33 EMR65851.1 - 4e-11 42.5 2.8 1.1e-10 41.2 2.3 2.0 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 EMR65851.1 - 1.2e-10 41.1 2.6 2.6e-10 40.0 2.6 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 EMR65851.1 - 1.1e-06 29.2 1.4 0.63 11.0 0.4 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box_4 PF15966.5 EMR65851.1 - 0.0052 16.7 2.2 0.022 14.6 2.2 2.1 1 1 0 1 1 1 1 F-box FAD-oxidase_C PF02913.19 EMR65852.1 - 1.1e-42 146.4 0.9 2.7e-42 145.1 0.9 1.5 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain Ribosomal_L27A PF00828.19 EMR65853.1 - 6.6e-32 110.9 0.4 1.2e-31 110.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Trp_halogenase PF04820.14 EMR65853.1 - 0.00061 18.8 0.5 0.9 8.3 0.1 3.3 2 1 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 EMR65853.1 - 0.099 12.2 0.6 0.2 11.2 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Sec62 PF03839.16 EMR65855.1 - 0.79 9.2 9.7 1.4 8.4 9.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Med19 PF10278.9 EMR65855.1 - 0.87 9.5 17.3 0.025 14.5 11.1 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 GST_C_3 PF14497.6 EMR65856.1 - 2.6e-06 27.5 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMR65856.1 - 5.9e-06 26.5 0.0 3.4e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR65856.1 - 8.9e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR65856.1 - 0.00011 22.1 0.1 0.00017 21.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR65856.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR65856.1 - 0.093 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.16 EMR65857.1 - 2.4e-14 53.0 21.1 2.4e-14 53.0 21.1 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2681 PF10883.8 EMR65857.1 - 0.56 10.6 2.8 0.82 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) GRA6 PF05084.13 EMR65859.1 - 0.0073 16.3 0.7 0.0083 16.1 0.7 1.0 1 0 0 1 1 1 1 Granule antigen protein (GRA6) SARAF PF06682.12 EMR65859.1 - 0.024 14.3 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2946 PF11162.8 EMR65859.1 - 0.16 12.7 0.7 0.22 12.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Amidoligase_2 PF12224.8 EMR65860.1 - 0.0074 16.0 0.0 0.8 9.3 0.0 2.6 2 1 0 2 2 2 2 Putative amidoligase enzyme Trehalase PF01204.18 EMR65861.1 - 1.2e-117 393.9 0.0 2.7e-116 389.4 0.0 2.0 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 EMR65861.1 - 2e-05 23.7 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase WD40 PF00400.32 EMR65862.1 - 8.4e-07 29.6 7.6 0.56 11.2 0.6 5.3 4 1 0 4 4 4 3 WD domain, G-beta repeat SnoaL_2 PF12680.7 EMR65863.1 - 0.00023 21.7 0.0 0.00027 21.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ank_2 PF12796.7 EMR65864.1 - 3.5e-40 136.5 0.0 4.4e-14 52.8 0.0 9.1 8 1 1 9 9 9 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR65864.1 - 1.7e-33 110.9 8.4 0.0022 18.3 0.0 13.3 14 0 0 14 14 14 6 Ankyrin repeat Ank_5 PF13857.6 EMR65864.1 - 8.8e-30 102.4 0.7 0.00026 21.2 0.0 9.8 10 1 1 11 11 11 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR65864.1 - 7.7e-27 93.3 0.4 9.1e-06 26.1 0.0 10.1 9 1 1 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 EMR65864.1 - 3.1e-26 90.6 4.8 0.0044 17.4 0.0 11.0 12 0 0 12 12 12 5 Ankyrin repeat Acetyltransf_3 PF13302.7 EMR65865.1 - 2.1e-29 103.0 0.0 2.5e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR65865.1 - 4.6e-07 30.1 0.1 6.6e-07 29.6 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMR65865.1 - 0.0037 17.4 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_transf_17 PF04724.13 EMR65866.1 - 2.9e-52 177.9 0.3 6.4e-52 176.7 0.3 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 17 UPF0258 PF06789.12 EMR65866.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) STT3 PF02516.14 EMR65867.1 - 1.1e-139 466.5 36.6 1.3e-134 449.8 34.6 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Pkinase PF00069.25 EMR65868.1 - 0.091 12.1 0.0 0.47 9.8 0.0 1.8 1 1 1 2 2 2 0 Protein kinase domain Sel1 PF08238.12 EMR65869.1 - 4.9e-14 52.4 4.4 0.0023 18.6 0.1 4.2 4 0 0 4 4 4 3 Sel1 repeat BAMBI PF06211.12 EMR65869.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Antifungal_pept PF11410.8 EMR65869.1 - 0.47 10.4 6.4 19 5.2 2.2 3.1 2 1 1 3 3 3 0 Antifungal peptide ATP-synt_E PF05680.12 EMR65870.1 - 2.1e-25 88.8 0.2 2.2e-25 88.8 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain Drf_GBD PF06371.13 EMR65870.1 - 0.019 14.5 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain COPIIcoated_ERV PF07970.12 EMR65871.1 - 8.1e-89 297.2 0.1 1.1e-88 296.9 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EMR65871.1 - 2.1e-30 104.9 0.1 9.7e-30 102.8 0.0 2.2 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Beta_elim_lyase PF01212.21 EMR65872.1 - 2.1e-66 224.2 0.0 3e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMR65872.1 - 3.3e-05 23.2 0.0 4.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMR65872.1 - 0.0017 16.9 0.0 0.0033 16.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMR65872.1 - 0.02 14.2 0.1 0.044 13.1 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Herpes_pp85 PF04637.12 EMR65872.1 - 0.25 9.7 2.4 0.36 9.2 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DXP_reductoisom PF02670.16 EMR65873.1 - 0.04 14.6 0.0 0.063 14.0 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 EMR65873.1 - 0.055 13.7 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EMR65873.1 - 0.19 10.9 0.0 0.45 9.6 0.0 1.6 1 1 1 2 2 2 0 Male sterility protein CENP-L PF13092.6 EMR65874.1 - 1.3e-59 201.0 0.0 3.6e-59 199.6 0.0 1.7 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 CENP-B_dimeris PF09026.10 EMR65874.1 - 0.1 13.0 3.1 16 6.0 0.4 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ank_4 PF13637.6 EMR65875.1 - 9.3e-14 51.6 0.4 9.5e-07 29.3 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR65875.1 - 3e-10 40.6 0.0 0.0024 18.4 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR65875.1 - 4.7e-10 38.8 0.2 0.0037 17.6 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EMR65875.1 - 1.1e-09 38.3 0.9 0.01 16.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EMR65875.1 - 1.6e-05 25.1 0.2 0.45 10.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EMR65875.1 - 0.0017 18.2 0.6 0.0017 18.2 0.6 2.8 2 1 0 2 2 2 1 KilA-N domain DUF2973 PF11189.8 EMR65875.1 - 0.034 14.2 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) SKG6 PF08693.10 EMR65875.1 - 0.042 13.3 2.6 0.11 12.0 2.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain USP8_interact PF08941.10 EMR65875.1 - 1.2 8.9 3.0 0.65 9.8 0.8 1.7 2 0 0 2 2 2 0 USP8 interacting Lebercilin PF15619.6 EMR65875.1 - 8.8 5.9 13.3 8.9 5.9 9.3 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Rbsn PF11464.8 EMR65876.1 - 1.3e-16 60.1 0.5 3.8e-16 58.5 0.5 1.9 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Seryl_tRNA_N PF02403.22 EMR65876.1 - 0.011 16.0 0.2 0.011 16.0 0.2 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HrpB2 PF09487.10 EMR65876.1 - 0.041 14.3 3.3 3.7 8.0 0.0 3.2 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB2) Lant_dehydr_C PF14028.6 EMR65876.1 - 0.061 12.9 0.2 0.061 12.9 0.2 1.9 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF3248 PF11609.8 EMR65876.1 - 0.095 12.6 0.5 0.25 11.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) CotJB PF12652.7 EMR65876.1 - 0.12 12.6 0.0 0.36 11.1 0.0 1.8 1 1 0 1 1 1 0 CotJB protein TMF_TATA_bd PF12325.8 EMR65876.1 - 0.48 10.7 6.1 0.35 11.1 3.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 EMR65876.1 - 0.79 9.9 4.7 16 5.7 0.0 3.0 3 0 0 3 3 3 0 bZIP transcription factor Uds1 PF15456.6 EMR65876.1 - 3.4 7.8 13.4 27 4.9 0.1 3.2 1 1 1 2 2 2 0 Up-regulated During Septation Acetyltransf_1 PF00583.25 EMR65877.1 - 8.5e-17 61.5 0.0 1.1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR65877.1 - 5.5e-08 32.8 0.0 7.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR65877.1 - 5.6e-08 32.6 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EMR65877.1 - 5.2e-07 30.0 0.0 8.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMR65877.1 - 0.00088 20.0 0.0 0.0012 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4349 PF14257.6 EMR65877.1 - 0.003 17.0 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Acetyltransf_4 PF13420.7 EMR65877.1 - 0.022 14.9 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 EMR65877.1 - 0.082 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ NAD_binding_7 PF13241.6 EMR65878.1 - 2.5e-28 98.6 0.0 5.1e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EMR65878.1 - 6.5e-25 86.6 0.0 1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EMR65878.1 - 1.7e-14 52.9 0.4 3.4e-14 52.0 0.4 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Cytotoxic PF09000.10 EMR65878.1 - 0.0012 19.1 0.1 0.09 13.1 0.0 2.3 2 0 0 2 2 2 1 Cytotoxic Pyr_redox_3 PF13738.6 EMR65878.1 - 0.0016 17.7 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Ead_Ea22 PF13935.6 EMR65878.1 - 0.22 12.2 0.0 0.37 11.4 0.0 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein SARG PF15385.6 EMR65879.1 - 2.6 7.2 7.9 2.7 7.1 7.9 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein p450 PF00067.22 EMR65880.1 - 5.3e-51 173.8 0.0 6.6e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 EMR65881.1 - 9e-12 45.2 0.0 2.8e-11 43.6 0.0 1.8 2 1 0 2 2 2 1 BTB/POZ domain SRAP PF02586.14 EMR65881.1 - 0.04 13.4 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 SOS response associated peptidase (SRAP) MFS_1 PF07690.16 EMR65882.1 - 3.7e-29 101.7 30.8 3.7e-29 101.7 30.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EMR65883.1 - 1.8e-24 86.3 75.8 1.8e-17 63.3 39.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin PF08613.11 EMR65885.1 - 3e-40 138.2 7.2 2.2e-24 86.7 0.1 2.7 2 1 1 3 3 3 2 Cyclin KOG2701 PF09762.9 EMR65885.1 - 0.081 13.1 0.3 4.9 7.4 0.0 2.1 1 1 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) DUF4484 PF14831.6 EMR65885.1 - 0.29 11.1 5.2 0.51 10.4 5.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Peptidase_M19 PF01244.21 EMR65887.1 - 1.4e-104 349.7 0.0 1.7e-104 349.5 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) SIS PF01380.22 EMR65887.1 - 0.12 12.2 0.1 1.4 8.8 0.0 2.1 1 1 1 2 2 2 0 SIS domain Amidase PF01425.21 EMR65888.1 - 1.7e-12 47.1 0.0 1e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 Amidase DUF2188 PF09954.9 EMR65888.1 - 0.21 11.7 0.5 16 5.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Peptidase_S8 PF00082.22 EMR65889.1 - 4.3e-31 108.3 23.3 5.6e-31 107.9 22.7 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR65889.1 - 5.9e-07 30.1 0.0 1.6e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 Proteasome PF00227.26 EMR65890.1 - 1.8e-44 151.5 0.4 2e-44 151.4 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit SpvD PF05563.12 EMR65890.1 - 0.072 12.7 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD MFS_1 PF07690.16 EMR65891.1 - 4e-12 45.7 19.9 8.1e-09 34.9 2.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65891.1 - 2e-06 26.9 2.5 2e-06 26.9 2.5 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 EMR65891.1 - 0.0065 15.1 6.6 0.13 10.8 1.8 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein DUF4781 PF16013.5 EMR65891.1 - 4.9 5.9 6.2 3 6.6 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4781) Evr1_Alr PF04777.13 EMR65892.1 - 2.7e-27 95.1 0.0 3.9e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family GRA6 PF05084.13 EMR65892.1 - 0.23 11.4 0.1 0.23 11.4 0.1 1.4 2 0 0 2 2 2 0 Granule antigen protein (GRA6) C2 PF00168.30 EMR65893.1 - 1.9e-11 44.2 0.0 3.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain p450 PF00067.22 EMR65894.1 - 3.1e-48 164.7 0.0 3.8e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.8 EMR65895.1 - 5.4e-18 65.1 0.0 1.3e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) HeLo PF14479.6 EMR65896.1 - 1.5e-08 34.7 0.9 0.001 19.0 0.1 2.8 1 1 1 2 2 2 2 Prion-inhibition and propagation adh_short PF00106.25 EMR65897.1 - 3.2e-26 92.0 0.0 1.6e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR65897.1 - 5.4e-13 49.1 0.0 1.3e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR65897.1 - 2.5e-09 37.3 0.1 3.7e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR65897.1 - 0.00017 21.1 0.0 0.0006 19.3 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMR65897.1 - 0.00042 19.9 0.0 0.00059 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family tRNA-synt_1d PF00750.19 EMR65898.1 - 4e-98 328.6 3.2 7.5e-98 327.7 3.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EMR65898.1 - 1.1e-27 96.6 0.1 2.2e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EMR65898.1 - 0.0051 17.4 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF4473 PF14747.6 EMR65898.1 - 0.054 14.0 0.2 1.7 9.2 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF3889 PF13028.6 EMR65898.1 - 0.057 13.4 1.1 0.095 12.6 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) DUF2080 PF09853.9 EMR65900.1 - 0.12 12.2 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) Med3 PF11593.8 EMR65900.1 - 2.8 7.0 5.4 4.1 6.5 5.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ferric_reduct PF01794.19 EMR65901.1 - 4.5e-19 68.8 13.2 1e-18 67.6 13.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMR65901.1 - 3.5e-16 59.7 0.2 5.1e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR65901.1 - 8.7e-13 48.3 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain TMEM208_SND2 PF05620.11 EMR65901.1 - 0.55 10.0 3.4 2.1 8.1 3.4 2.0 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 p450 PF00067.22 EMR65902.1 - 1.8e-55 188.5 0.0 2.6e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RINGv PF12906.7 EMR65903.1 - 2e-16 59.9 9.0 3.5e-16 59.1 9.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EMR65903.1 - 0.0045 17.3 8.9 0.0079 16.5 8.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EMR65903.1 - 0.088 12.9 1.9 0.2 11.7 1.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EMR65903.1 - 2.3 8.2 5.0 4.5 7.2 5.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EMR65903.1 - 6.1 6.7 6.4 11 5.9 6.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3328 PF11807.8 EMR65904.1 - 1.7e-44 152.2 2.2 2.6e-44 151.6 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 4HBT_3 PF13622.6 EMR65905.1 - 3.3e-32 112.7 4.8 4.7e-31 108.9 4.8 2.0 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMR65905.1 - 8.8e-12 45.0 0.0 4.2e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA thioesterase YHYH PF14240.6 EMR65906.1 - 0.12 12.3 0.1 0.91 9.4 0.1 2.1 2 0 0 2 2 2 0 YHYH protein p450 PF00067.22 EMR65907.1 - 4.1e-10 39.0 0.0 4.6e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Esterase_phd PF10503.9 EMR65908.1 - 1.6e-25 89.9 0.8 2.4e-25 89.4 0.8 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMR65908.1 - 7.8e-09 35.3 0.5 1.2e-08 34.7 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EMR65908.1 - 0.011 15.7 0.1 0.016 15.1 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 EMR65908.1 - 0.013 14.4 0.2 0.02 13.8 0.2 1.5 1 1 0 1 1 1 0 Carboxylesterase family Peptidase_S10 PF00450.22 EMR65908.1 - 0.021 14.2 0.2 0.033 13.6 0.2 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Glycos_transf_1 PF00534.20 EMR65909.1 - 2.4e-35 121.6 0.0 3.6e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMR65909.1 - 6.4e-29 101.1 0.0 1.1e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMR65909.1 - 1e-15 58.2 0.0 1.3e-12 48.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EMR65909.1 - 1.2e-12 48.6 0.1 4.3e-12 46.8 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EMR65909.1 - 2.2e-10 40.8 0.0 4.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 NAD_binding_4 PF07993.12 EMR65910.1 - 9.5e-12 44.6 0.0 1.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EMR65911.1 - 4e-77 259.6 0.0 1.7e-74 250.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EMR65911.1 - 1.3e-59 202.1 0.0 8.5e-37 126.9 0.0 2.2 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EMR65911.1 - 2.3e-28 98.4 0.6 3.8e-15 56.0 0.0 3.7 3 0 0 3 3 3 2 Phosphopantetheine attachment site Inositol_P PF00459.25 EMR65912.1 - 7.9e-50 169.9 0.1 5.3e-49 167.2 0.1 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family Abhydrolase_1 PF00561.20 EMR65913.1 - 4.4e-17 62.6 0.1 6.5e-16 58.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR65913.1 - 4.5e-12 47.0 2.3 6.9e-12 46.4 2.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EMR65913.1 - 0.0038 16.0 0.0 0.0067 15.2 0.0 1.4 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 EMR65913.1 - 0.011 15.1 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ISN1 PF06437.11 EMR65913.1 - 0.055 12.4 0.1 0.17 10.8 0.0 1.8 3 0 0 3 3 3 0 IMP-specific 5'-nucleotidase Fungal_trans PF04082.18 EMR65914.1 - 5.8e-15 55.0 0.1 1.3e-14 53.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 EMR65915.1 - 9.9e-13 49.0 0.0 1.5e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold YGGT PF02325.17 EMR65915.1 - 0.097 13.1 0.6 0.41 11.1 0.3 2.0 2 0 0 2 2 2 0 YGGT family Clr5 PF14420.6 EMR65916.1 - 5e-22 77.9 0.8 9.5e-22 77.0 0.8 1.5 1 0 0 1 1 1 1 Clr5 domain rhaM PF05336.13 EMR65917.1 - 0.032 14.3 5.0 0.024 14.7 2.9 1.8 2 0 0 2 2 2 0 L-rhamnose mutarotase FAD_binding_3 PF01494.19 EMR65918.1 - 2.7e-21 76.2 0.0 4.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR65918.1 - 5e-05 22.7 0.1 0.076 12.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR65918.1 - 0.0032 17.1 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR65918.1 - 0.024 13.5 0.0 5.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EMR65918.1 - 0.025 14.6 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMR65918.1 - 0.036 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 EMR65918.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sugar_tr PF00083.24 EMR65919.1 - 6.1e-45 153.9 5.7 7e-45 153.7 5.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR65919.1 - 4.4e-09 35.7 10.5 5.4e-09 35.4 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3188 PF11384.8 EMR65919.1 - 0.038 13.7 0.0 0.14 11.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) AAA PF00004.29 EMR65920.1 - 2e-08 34.7 0.0 5e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CHASE8 PF17152.4 EMR65920.1 - 0.076 13.3 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Periplasmic sensor domain CagY_I PF14585.6 EMR65920.1 - 1 9.5 9.5 2.2 8.4 0.8 2.7 2 0 0 2 2 2 0 CagY type 1 repeat Cu_amine_oxid PF01179.20 EMR65921.1 - 6e-163 542.5 0.0 7.3e-163 542.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EMR65921.1 - 1.1e-17 64.2 0.1 2.3e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EMR65921.1 - 5.2e-10 39.4 0.0 9.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain HgmA PF04209.13 EMR65922.1 - 8.6e-188 624.3 0.0 9.9e-188 624.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase MFS_1 PF07690.16 EMR65923.1 - 8e-28 97.4 8.2 9.7e-28 97.1 8.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR65923.1 - 2.4e-05 23.8 1.5 3.6e-05 23.2 1.5 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB CLN3 PF02487.17 EMR65923.1 - 0.0081 15.2 0.4 0.016 14.3 0.2 1.6 2 0 0 2 2 2 1 CLN3 protein DUF3094 PF11293.8 EMR65923.1 - 0.017 14.8 0.5 1.2 8.9 0.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3094) CD20 PF04103.15 EMR65923.1 - 0.24 11.5 5.1 0.72 9.9 4.9 2.0 1 1 0 1 1 1 0 CD20-like family 4HBT PF03061.22 EMR65924.1 - 3.6e-07 30.4 0.1 6.2e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 Thioesterase superfamily NAD_binding_8 PF13450.6 EMR65925.1 - 3.3e-12 46.5 0.0 9.9e-09 35.3 0.0 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR65925.1 - 9e-12 44.9 0.0 9.3e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR65925.1 - 1.2e-11 44.5 0.0 0.00011 21.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMR65925.1 - 5.7e-10 38.2 0.0 4.9e-07 28.6 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Thi4 PF01946.17 EMR65925.1 - 4.5e-08 32.6 0.2 3.1e-06 26.6 0.0 2.7 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 EMR65925.1 - 1.1e-06 28.5 1.7 0.00049 19.8 0.1 3.2 3 1 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EMR65925.1 - 4.7e-06 26.0 0.1 0.00042 19.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EMR65925.1 - 7.2e-06 26.5 0.0 0.015 15.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR65925.1 - 0.00012 21.3 0.2 0.034 13.2 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR65925.1 - 0.00012 21.3 0.5 0.0004 19.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EMR65925.1 - 0.00043 19.7 0.1 1 8.6 0.0 3.2 3 1 1 4 4 4 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EMR65925.1 - 0.00068 19.7 0.6 1.4 8.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EMR65925.1 - 0.0067 16.5 0.0 0.12 12.4 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 EMR65925.1 - 0.0068 15.8 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMR65925.1 - 0.0086 15.2 4.4 0.026 13.6 0.1 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EMR65925.1 - 0.0095 15.2 0.1 0.027 13.8 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EMR65925.1 - 0.014 14.2 1.1 0.034 12.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein MCRA PF06100.11 EMR65925.1 - 0.018 13.9 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 MCRA family NAD_Gly3P_dh_N PF01210.23 EMR65925.1 - 0.022 14.7 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EMR65925.1 - 0.031 13.9 0.2 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EMR65925.1 - 0.067 12.0 1.4 5.5 5.7 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_7 PF13241.6 EMR65925.1 - 0.12 12.8 0.0 0.49 10.9 0.0 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding Mqo PF06039.15 EMR65925.1 - 0.13 10.8 0.0 0.32 9.5 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Oxysterol_BP PF01237.18 EMR65926.1 - 5e-51 173.7 0.0 1.8e-41 142.2 0.0 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein DUF2722 PF10846.8 EMR65928.1 - 0.00015 20.9 4.6 0.00015 20.9 4.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) FAM110_C PF14160.6 EMR65928.1 - 0.14 13.2 2.1 0.3 12.2 2.1 1.6 1 0 0 1 1 1 0 Centrosome-associated C terminus Pex14_N PF04695.13 EMR65928.1 - 0.74 10.5 19.4 0.31 11.7 9.3 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 EMR65928.1 - 8.3 5.1 5.5 12 4.5 5.5 1.2 1 0 0 1 1 1 0 Presenilin zf-C2H2_3 PF13878.6 EMR65929.1 - 0.44 10.4 7.7 0.15 11.9 0.4 3.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Sugar_tr PF00083.24 EMR65930.1 - 1.9e-33 116.0 20.0 1.4e-25 90.1 7.3 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR65930.1 - 7.3e-29 100.8 23.6 7.3e-29 100.8 23.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 EMR65930.1 - 0.0012 17.7 14.1 0.0018 17.2 14.1 1.2 1 0 0 1 1 1 1 LacY proton/sugar symporter BT1 PF03092.16 EMR65930.1 - 0.0058 14.9 0.3 0.011 14.1 0.3 1.4 1 0 0 1 1 1 1 BT1 family DUF1156 PF06634.12 EMR65930.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Transp_cyt_pur PF02133.15 EMR65931.1 - 6.5e-84 282.2 31.0 7.9e-84 281.9 31.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TAL_FSA PF00923.19 EMR65932.1 - 2.3e-48 165.0 0.1 2.7e-48 164.8 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Xan_ur_permease PF00860.20 EMR65933.1 - 1.2e-63 215.2 35.5 2.3e-62 210.9 35.5 2.0 1 1 0 1 1 1 1 Permease family ANAPC4_WD40 PF12894.7 EMR65934.1 - 8.6e-08 32.4 0.0 4e-05 23.8 0.0 3.5 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMR65934.1 - 0.00045 21.0 8.2 0.8 10.7 0.1 5.2 7 0 0 7 7 7 2 WD domain, G-beta repeat Nup160 PF11715.8 EMR65934.1 - 0.0022 16.7 0.0 0.0032 16.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 CDC45 PF02724.14 EMR65934.1 - 0.0067 14.8 5.2 0.0092 14.3 5.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EMR65934.1 - 0.98 7.5 6.1 1.3 7.1 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 EMR65934.1 - 3.2 7.8 12.4 5.6 7.0 12.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Oxidored_molyb PF00174.19 EMR65935.1 - 2.2e-55 186.9 0.0 3.1e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EMR65935.1 - 1.2e-24 86.8 3.1 1e-15 58.0 0.6 3.5 4 0 0 4 4 4 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EMR65935.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Sugar_tr PF00083.24 EMR65937.1 - 2.1e-120 402.7 25.6 3e-120 402.2 25.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR65937.1 - 5.2e-30 104.6 52.9 9e-26 90.6 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Defensin_propep PF00879.18 EMR65938.1 - 0.28 11.5 1.0 0.39 11.0 1.0 1.2 1 0 0 1 1 1 0 Defensin propeptide UbiA PF01040.18 EMR65939.1 - 5.1e-59 199.6 18.3 6.9e-59 199.2 18.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Mito_carr PF00153.27 EMR65939.1 - 0.015 15.2 0.2 0.97 9.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial carrier protein Ferredoxin_N PF16947.5 EMR65939.1 - 0.12 12.4 3.4 0.25 11.5 3.4 1.4 1 0 0 1 1 1 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding mRNA_triPase PF02940.15 EMR65940.1 - 8.9e-51 172.7 0.0 1.2e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Dicty_REP PF05086.12 EMR65940.1 - 0.3 9.0 0.2 0.4 8.6 0.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein adh_short PF00106.25 EMR65941.1 - 9.4e-08 31.7 0.0 6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMR65941.1 - 6.3e-06 26.2 0.0 9.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR65941.1 - 0.00034 20.2 0.1 0.00065 19.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMR65941.1 - 0.00064 19.0 0.0 0.00091 18.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EMR65941.1 - 0.0073 15.7 0.1 0.0099 15.3 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sulfotransfer_3 PF13469.6 EMR65941.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family MutS_V PF00488.21 EMR65943.1 - 2.7e-65 219.9 1.2 4.5e-65 219.2 0.2 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EMR65943.1 - 3e-43 148.3 0.0 8.4e-43 146.8 0.0 1.8 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EMR65943.1 - 8.6e-33 113.0 0.1 1.8e-32 111.9 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EMR65943.1 - 2.3e-13 50.6 0.6 9.9e-13 48.6 0.1 2.3 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EMR65943.1 - 7.8e-12 45.4 0.9 2e-11 44.1 0.9 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 EMR65943.1 - 0.0031 18.0 5.2 0.0049 17.4 0.1 3.0 3 0 0 3 3 3 1 AAA domain SPT6_acidic PF14632.6 EMR65943.1 - 0.0079 16.8 12.1 0.049 14.2 8.6 2.9 1 1 1 2 2 2 1 Acidic N-terminal SPT6 AAA_29 PF13555.6 EMR65943.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EMR65943.1 - 0.068 13.0 1.5 0.096 12.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 EMR65943.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain CCDC85 PF10226.9 EMR65943.1 - 0.15 11.7 2.1 2 8.0 0.2 2.7 2 0 0 2 2 2 0 CCDC85 family DUF3461 PF11944.8 EMR65943.1 - 0.25 11.5 2.0 0.71 10.0 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) CCDC24 PF15669.5 EMR65943.1 - 1.8 8.4 7.4 1.2 8.9 3.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family RPN2_C PF18004.1 EMR65944.1 - 2e-49 167.6 3.6 2e-49 167.6 3.6 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EMR65944.1 - 1.8e-39 132.2 23.0 1.2e-08 35.0 0.0 8.7 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EMR65944.1 - 2.1e-21 76.1 0.0 8.4e-15 54.9 0.0 5.1 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EMR65944.1 - 2.8e-06 27.7 0.9 0.0023 18.4 0.0 5.1 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 EMR65944.1 - 9.2e-06 25.5 0.0 1.1 9.8 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EMR65944.1 - 0.0031 17.6 0.0 1.4 8.9 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Smg8_Smg9 PF10220.9 EMR65944.1 - 0.069 11.4 1.6 0.12 10.7 1.6 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Mad3_BUB1_II PF08171.11 EMR65944.1 - 0.16 12.2 1.2 0.41 10.8 1.2 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 DUF913 PF06025.12 EMR65944.1 - 5.8 5.8 7.1 2.3 7.1 3.6 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) AP_endonuc_2 PF01261.24 EMR65945.1 - 1.1e-31 110.0 0.0 1.7e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Carot_N PF09150.10 EMR65945.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal AATase PF07247.12 EMR65946.1 - 6.1e-08 31.7 0.0 2.3e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Alcohol acetyltransferase NAD_binding_4 PF07993.12 EMR65947.1 - 1.8e-27 96.1 0.0 9.9e-26 90.4 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EMR65947.1 - 7e-17 61.1 0.0 1.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EMR65947.1 - 1.7e-14 53.8 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR65947.1 - 8.8e-09 35.6 0.0 1.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EMR65947.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EMR65947.1 - 0.00019 22.3 0.0 0.00045 21.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 EMR65947.1 - 0.2 11.1 0.0 4.6 6.6 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Methyltransf_3 PF01596.17 EMR65948.1 - 5.7e-11 42.0 0.0 6.4e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 EMR65948.1 - 0.0002 21.2 0.1 0.00023 21.0 0.1 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GDPD PF03009.17 EMR65949.1 - 2.7e-13 50.2 0.0 4.3e-13 49.6 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Nif11 PF07862.11 EMR65949.1 - 0.11 12.9 0.0 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 Nif11 domain DUF3431 PF11913.8 EMR65950.1 - 5.1e-42 144.1 0.0 3.2e-30 105.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) Trypan_PARP PF05887.11 EMR65950.1 - 0.42 10.6 16.3 0.84 9.6 16.3 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 EMR65950.1 - 4.1 6.5 6.2 5.7 6.0 6.2 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 ABC_tran PF00005.27 EMR65951.1 - 0.0022 18.5 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMR65951.1 - 0.0043 17.0 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EMR65951.1 - 0.0046 17.4 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EMR65951.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMR65951.1 - 0.011 15.6 0.9 0.038 13.9 0.9 2.0 1 1 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EMR65951.1 - 0.018 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EMR65951.1 - 0.029 14.7 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMR65951.1 - 0.033 13.9 0.2 0.064 13.0 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 EMR65951.1 - 0.049 13.6 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 EMR65951.1 - 0.056 13.9 1.1 0.09 13.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMR65951.1 - 0.086 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR65951.1 - 0.087 13.2 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 EMR65951.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Peroxidase_2 PF01328.17 EMR65952.1 - 4.9e-46 157.6 0.0 6.4e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Glyco_hydro_18 PF00704.28 EMR65953.1 - 1.3e-68 232.0 0.0 1.5e-68 231.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.6 EMR65953.1 - 0.0013 18.8 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 15 YadA_anchor PF03895.15 EMR65953.1 - 0.066 13.3 0.7 0.17 12.0 0.7 1.6 1 0 0 1 1 1 0 YadA-like membrane anchor domain Glyco_hydro_47 PF01532.20 EMR65954.1 - 6e-162 539.7 0.0 6.9e-162 539.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Toxin_ToxA PF11584.8 EMR65954.1 - 0.038 14.0 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA FAD_binding_4 PF01565.23 EMR65955.1 - 6.3e-23 81.1 0.2 1.3e-22 80.0 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR65955.1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like MARVEL PF01284.23 EMR65956.1 - 4e-10 39.9 27.1 7e-10 39.1 27.1 1.4 1 1 0 1 1 1 1 Membrane-associating domain Myb_DNA-binding PF00249.31 EMR65957.1 - 2.4e-09 37.2 0.2 8.1e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 EMR65957.1 - 3.4e-08 33.4 0.1 0.41 10.8 0.0 3.7 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Myb_DNA-bind_6 PF13921.6 EMR65957.1 - 1.7e-06 28.1 0.8 7.5e-06 26.1 0.7 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 EMR65957.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain YajC PF02699.15 EMR65957.1 - 6.6 6.7 5.5 23 4.9 1.7 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit DUF1635 PF07795.11 EMR65957.1 - 9.9 6.0 10.5 3.2 7.6 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) ADH_N PF08240.12 EMR65958.1 - 2.9e-17 62.5 1.4 8.7e-17 61.0 0.6 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR65958.1 - 5.1e-07 29.7 0.9 7.3e-06 26.0 0.9 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EMR65958.1 - 0.00022 21.1 0.6 0.00022 21.1 0.6 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.14 EMR65958.1 - 0.0007 18.4 0.5 0.00099 17.9 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EMR65958.1 - 0.022 14.1 0.2 0.034 13.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EMR65958.1 - 0.061 12.4 1.2 0.11 11.5 1.2 1.4 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 EMR65958.1 - 0.095 12.2 0.2 0.58 9.6 0.1 2.3 2 1 0 2 2 2 0 Glucose dehydrogenase C-terminus DAO PF01266.24 EMR65958.1 - 0.13 11.9 0.5 0.19 11.2 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Asp_decarbox PF02261.16 EMR65958.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase NACHT PF05729.12 EMR65959.1 - 4.1e-12 46.3 0.1 1.2e-11 44.8 0.1 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMR65959.1 - 7.4e-07 29.7 1.9 1.5e-06 28.7 0.1 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EMR65959.1 - 1e-06 29.0 0.0 4.7e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMR65959.1 - 0.0012 19.4 0.0 0.005 17.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMR65959.1 - 0.0018 18.8 0.0 0.0061 17.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.18 EMR65959.1 - 0.0075 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 EMR65959.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 EMR65959.1 - 0.036 13.3 0.3 0.95 8.6 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Ploopntkinase1 PF18748.1 EMR65959.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_29 PF13555.6 EMR65959.1 - 0.044 13.5 0.2 0.093 12.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EMR65959.1 - 0.066 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 EMR65959.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 EMR65959.1 - 0.095 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EMR65959.1 - 0.098 12.6 0.1 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 EMR65959.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EMR65959.1 - 1.8 9.0 6.6 29 5.1 0.1 2.9 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EMR65960.1 - 2e-17 63.7 0.0 2e-17 63.7 0.0 2.7 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EMR65960.1 - 1.9e-10 40.8 0.0 9e-10 38.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMR65960.1 - 2e-05 24.2 5.4 4.8e-05 23.0 1.3 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EMR65960.1 - 0.0036 16.4 0.0 0.0091 15.1 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 EMR65960.1 - 0.0086 16.0 1.9 3 7.7 0.0 3.2 3 1 0 3 3 3 1 RsgA GTPase cobW PF02492.19 EMR65960.1 - 0.026 14.1 0.8 0.4 10.2 0.8 2.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EMR65960.1 - 0.037 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EMR65960.1 - 0.088 13.1 0.3 3.8 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Prominin PF05478.11 EMR65960.1 - 0.11 10.4 0.2 0.21 9.5 0.2 1.4 1 0 0 1 1 1 0 Prominin HSR PF03172.13 EMR65960.1 - 0.14 12.3 0.0 0.54 10.5 0.0 2.0 1 0 0 1 1 1 0 HSR domain Roc PF08477.13 EMR65960.1 - 0.3 11.3 2.9 1.2 9.4 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Roughex PF06020.11 EMR65960.1 - 0.39 9.8 5.3 0.74 8.9 5.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein SUIM_assoc PF16619.5 EMR65960.1 - 0.47 10.6 13.3 1.5 9.0 13.3 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 EMR65960.1 - 0.66 9.1 7.2 1.4 8.0 7.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_24 PF13479.6 EMR65960.1 - 0.71 9.6 3.2 4.2 7.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Spt20 PF12090.8 EMR65960.1 - 2.2 7.8 11.8 5 6.7 11.8 1.5 1 0 0 1 1 1 0 Spt20 family SPX PF03105.19 EMR65960.1 - 5.7 6.8 12.6 2.3 8.1 7.6 2.2 2 0 0 2 2 2 0 SPX domain Peptidase_C78 PF07910.13 EMR65961.1 - 3.1e-50 170.6 0.0 2.1e-27 96.0 0.0 2.0 1 1 1 2 2 2 2 Peptidase family C78 Hemerythrin PF01814.23 EMR65962.1 - 4.4e-13 50.0 4.1 6.4e-13 49.5 4.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain FAD_binding_4 PF01565.23 EMR65963.1 - 6.4e-17 61.6 0.1 8.3e-15 54.7 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 EMR65964.1 - 4.9e-36 124.4 13.7 4.9e-36 124.4 13.7 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR65964.1 - 3.1e-13 49.4 6.1 3.1e-13 49.4 6.1 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EMR65964.1 - 3e-06 26.0 3.7 5.5e-06 25.1 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2_1 PF04971.12 EMR65964.1 - 0.43 10.6 6.4 9.6 6.3 0.1 3.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S HMG_box PF00505.19 EMR65965.1 - 2.6e-21 75.8 0.4 5.6e-21 74.7 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR65965.1 - 6.8e-06 26.6 0.2 6.8e-06 26.6 0.2 2.1 2 0 0 2 2 2 1 HMG-box domain TFIIA PF03153.13 EMR65965.1 - 0.0031 17.6 2.3 0.0031 17.6 2.3 2.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit KGG PF10685.9 EMR65966.1 - 1.6e-25 88.5 16.8 1.6e-10 40.9 1.1 3.5 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif GHL6 PF14871.6 EMR65968.1 - 5.1e-26 91.5 0.0 8.9e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 Glyco_hydro_42M PF08532.10 EMR65968.1 - 1.2e-08 34.7 0.0 2.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42 PF02449.15 EMR65968.1 - 2.2e-05 24.0 0.0 9.1e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase GHL10 PF02638.15 EMR65968.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 DUF4350 PF14258.6 EMR65968.1 - 0.059 13.8 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Aldedh PF00171.22 EMR65970.1 - 6.9e-11 41.3 0.1 3.1e-07 29.3 0.0 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family LigB PF02900.18 EMR65970.1 - 6.6e-08 31.9 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short_C2 PF13561.6 EMR65971.1 - 5.7e-47 160.2 0.0 6.7e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR65971.1 - 1.2e-39 135.8 0.0 1.5e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR65971.1 - 7.9e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Histidinol_dh PF00815.20 EMR65973.1 - 1e-136 456.2 0.0 1.3e-136 455.9 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Prok_Ub PF14454.6 EMR65974.1 - 0.039 13.6 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic Ubiquitin GPI-anchored PF10342.9 EMR65974.1 - 0.051 14.3 0.1 0.079 13.7 0.1 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PepX_C PF08530.10 EMR65975.1 - 1.4e-36 126.5 0.1 2.1e-36 126.0 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EMR65975.1 - 1.4e-21 77.3 0.0 2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FAD_binding_3 PF01494.19 EMR65976.1 - 5.4e-23 81.8 0.0 7.9e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 EMR65976.1 - 1.9e-14 53.8 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 EMR65976.1 - 2.3e-07 31.0 0.3 8.2e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Cupin_2 PF07883.11 EMR65976.1 - 2.6e-07 30.3 0.0 7e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Pyr_redox_2 PF07992.14 EMR65976.1 - 4.7e-07 29.3 0.2 1.9e-06 27.3 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR65976.1 - 5.2e-06 26.3 0.6 1.2e-05 25.1 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR65976.1 - 0.00026 20.2 0.4 0.00041 19.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EMR65976.1 - 0.0018 18.8 0.4 0.0066 17.0 0.4 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR65976.1 - 0.0038 16.2 0.0 0.013 14.3 0.0 1.9 3 0 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EMR65976.1 - 0.0052 15.9 0.0 0.033 13.2 0.0 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EMR65976.1 - 0.017 14.4 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EMR65976.1 - 0.026 13.8 0.1 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 EMR65976.1 - 0.05 12.4 0.1 0.074 11.8 0.1 1.2 1 0 0 1 1 1 0 MCRA family Cupin_1 PF00190.22 EMR65976.1 - 0.12 12.0 0.1 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 Cupin FAD_binding_4 PF01565.23 EMR65976.1 - 0.13 12.0 0.1 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EMR65976.1 - 0.15 10.8 0.2 0.22 10.2 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein NmrA PF05368.13 EMR65977.1 - 5.4e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR65977.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding SRP19 PF01922.17 EMR65978.1 - 5e-32 110.7 0.1 7.1e-32 110.2 0.1 1.2 1 0 0 1 1 1 1 SRP19 protein adh_short_C2 PF13561.6 EMR65979.1 - 9.4e-32 110.4 0.4 1.5e-31 109.8 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR65979.1 - 1.3e-30 106.3 0.0 2.1e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR65979.1 - 2.5e-05 24.2 0.3 4.5e-05 23.4 0.3 1.3 1 0 0 1 1 1 1 KR domain Metallophos PF00149.28 EMR65980.1 - 2.5e-06 28.2 0.2 3.7e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box PF00646.33 EMR65982.1 - 0.057 13.3 0.4 0.15 11.9 0.4 1.7 1 0 0 1 1 1 0 F-box domain TIP49 PF06068.13 EMR65983.1 - 1.2e-164 547.7 0.0 1.5e-164 547.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EMR65983.1 - 4.8e-25 87.5 0.3 1.3e-24 86.1 0.3 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EMR65983.1 - 3.7e-10 40.3 0.9 3.2e-06 27.6 0.1 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMR65983.1 - 1.6e-08 34.5 0.0 6e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR65983.1 - 3.5e-05 24.1 0.2 0.2 11.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EMR65983.1 - 0.00012 22.4 0.2 0.00037 20.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMR65983.1 - 0.00015 22.2 0.2 0.0011 19.4 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EMR65983.1 - 0.0012 19.2 1.5 0.19 12.1 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMR65983.1 - 0.0019 18.2 0.2 0.054 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EMR65983.1 - 0.0029 17.2 0.1 0.027 14.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMR65983.1 - 0.017 15.7 0.1 0.053 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 EMR65983.1 - 0.021 14.6 0.1 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EMR65983.1 - 0.024 14.0 0.1 0.67 9.3 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 EMR65983.1 - 0.025 13.8 0.1 0.049 12.9 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 EMR65983.1 - 0.031 14.0 0.2 0.061 13.1 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EMR65983.1 - 0.039 13.7 0.3 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMR65983.1 - 0.14 11.4 0.1 0.36 10.1 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EMR65983.1 - 0.16 11.5 0.3 0.3 10.6 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region Phytase-like PF13449.6 EMR65984.1 - 1.9e-36 126.5 0.0 2.4e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase FAD_binding_3 PF01494.19 EMR65985.1 - 2.3e-14 53.4 0.0 1.8e-13 50.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EMR65985.1 - 0.00045 19.4 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EMR65985.1 - 0.0012 18.5 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR65985.1 - 0.012 14.4 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EMR65985.1 - 0.026 13.7 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Med10 PF09748.9 EMR65986.1 - 4.2e-51 172.0 0.1 5.9e-51 171.5 0.1 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex ETS_PEA3_N PF04621.13 EMR65986.1 - 0.011 15.6 0.8 0.013 15.4 0.8 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain RCS1 PF07326.11 EMR65986.1 - 0.076 12.9 3.4 0.11 12.4 3.4 1.2 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 DUF3877 PF12993.7 EMR65986.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF4972 PF16342.5 EMR65986.1 - 0.16 11.7 0.1 0.99 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) Siah-Interact_N PF09032.11 EMR65986.1 - 0.17 12.2 0.3 1.7 9.0 0.0 2.6 2 1 1 3 3 3 0 Siah interacting protein, N terminal Sporozoite_P67 PF05642.11 EMR65986.1 - 0.19 9.8 6.0 0.28 9.2 4.8 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen SSP160 PF06933.11 EMR65986.1 - 0.89 7.7 8.5 1.2 7.3 8.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Iso_dh PF00180.20 EMR65987.1 - 1.5e-123 412.4 0.0 1.7e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase p450 PF00067.22 EMR65988.1 - 8.4e-17 61.1 0.1 9.7e-17 60.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 EMR65989.1 - 0.11 11.1 0.2 0.45 9.1 0.1 2.1 2 1 0 2 2 2 0 Transferase family RPA_C PF08784.11 EMR65990.1 - 5.1e-18 65.6 0.0 1e-17 64.7 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EMR65990.1 - 3.3e-09 36.6 0.1 7.2e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EMR65990.1 - 5.9e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 2OG-FeII_Oxy PF03171.20 EMR65991.1 - 1.6e-18 67.1 0.0 2.6e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMR65991.1 - 8.3e-17 62.0 0.0 1.4e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PcfK PF14058.6 EMR65991.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 2 0 0 2 2 2 0 PcfK-like protein NUDIX PF00293.28 EMR65992.1 - 7.1e-26 90.8 0.0 1e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.7 EMR65993.1 - 2.7e-06 27.7 0.0 6.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR65993.1 - 3.7e-05 23.9 0.0 6.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR65993.1 - 7e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR65993.1 - 0.00075 19.6 0.2 0.0021 18.1 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR65993.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 EMR65993.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase bZIP_1 PF00170.21 EMR65994.1 - 3.8e-08 33.3 13.8 6.5e-08 32.6 13.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 EMR65994.1 - 1.6e-07 31.4 6.6 4.6e-06 26.6 0.0 2.0 1 1 1 2 2 2 1 Transcription factor PAP1 SHE3 PF17078.5 EMR65994.1 - 0.00039 20.2 5.2 0.00056 19.7 5.2 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 EMR65994.1 - 0.00087 19.8 9.2 0.0015 19.0 9.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor V_ATPase_I PF01496.19 EMR65994.1 - 0.0043 15.1 0.3 0.0054 14.7 0.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ADIP PF11559.8 EMR65994.1 - 0.016 15.3 10.9 0.23 11.5 11.8 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 EMR65994.1 - 0.23 11.6 16.8 3.2 7.9 16.5 2.3 1 1 1 2 2 2 0 Basic region leucine zipper FlaC_arch PF05377.11 EMR65994.1 - 0.23 11.9 1.5 0.44 11.0 1.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) GvpL_GvpF PF06386.11 EMR65994.1 - 0.44 10.4 4.2 0.71 9.7 4.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DivIC PF04977.15 EMR65994.1 - 1 9.2 4.8 2.1 8.2 4.8 1.6 1 0 0 1 1 1 0 Septum formation initiator SVIP PF15811.5 EMR65994.1 - 2.9 8.4 11.4 7.9 7.0 9.5 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein M PF02370.16 EMR65994.1 - 6.2 7.7 7.9 5.7 7.9 1.2 2.8 1 1 0 2 2 2 0 M protein repeat UDPGT PF00201.18 EMR65995.1 - 3.4e-07 29.4 0.0 4.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EMR65995.1 - 1.2e-05 25.4 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain KdpD PF02702.17 EMR65995.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Glyco_trans_4_2 PF13477.6 EMR65995.1 - 0.13 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Glyco_transf_28 PF03033.20 EMR65995.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain TauD PF02668.16 EMR65996.1 - 1.4e-43 149.6 0.1 2.1e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4238 PF14022.6 EMR65997.1 - 1.2e-72 244.8 0.4 1.9e-72 244.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Spore_YpjB PF09577.10 EMR65997.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) PGDH_C PF16896.5 EMR65997.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term DUF1485 PF07364.12 EMR65998.1 - 9.9e-110 366.3 0.1 1.2e-109 366.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 EMR65998.1 - 1.6e-57 194.5 0.1 2.6e-57 193.9 0.1 1.3 1 0 0 1 1 1 1 MlrC C-terminus COG5 PF10392.9 EMR65999.1 - 0.35 11.0 4.2 0.56 10.4 2.7 2.0 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 EMR65999.1 - 0.43 10.6 4.0 0.85 9.7 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MFS_5 PF05631.14 EMR66000.1 - 9.2e-32 110.3 0.8 3.4e-25 88.7 0.7 2.2 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EMR66000.1 - 3.8e-13 49.1 14.6 2.2e-12 46.6 6.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR66000.1 - 0.00011 21.2 0.2 0.00069 18.6 0.0 2.3 2 1 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 EMR66000.1 - 0.00024 20.1 0.9 0.00024 20.1 0.9 2.6 3 1 1 4 4 4 1 Sugar (and other) transporter adh_short PF00106.25 EMR66001.1 - 5e-25 88.1 0.0 1.3e-24 86.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66001.1 - 7.8e-16 58.3 0.0 1.6e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66001.1 - 1.8e-06 28.0 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Clr5 PF14420.6 EMR66002.1 - 2.9e-20 72.2 2.4 6.4e-20 71.1 2.4 1.6 1 0 0 1 1 1 1 Clr5 domain RTA1 PF04479.13 EMR66003.1 - 2.6e-31 108.8 3.4 3.5e-31 108.4 3.4 1.2 1 0 0 1 1 1 1 RTA1 like protein NAD_binding_10 PF13460.6 EMR66005.1 - 9.4e-16 58.2 0.0 1.7e-15 57.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR66005.1 - 1.1e-15 57.8 0.0 1.5e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EMR66005.1 - 4e-05 23.9 0.0 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EMR66005.1 - 0.012 16.1 0.8 0.043 14.3 0.8 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EMR66005.1 - 0.017 15.8 0.2 0.051 14.3 0.1 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Epimerase PF01370.21 EMR66005.1 - 0.052 13.0 0.0 0.21 11.0 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMR66005.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein NepR PF18557.1 EMR66006.1 - 0.099 12.3 1.8 0.16 11.6 0.1 2.3 2 0 0 2 2 2 0 Anti-sigma factor NepR Transferase PF02458.15 EMR66007.1 - 4.8e-15 55.2 0.0 3.4e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Transferase family Peptidase_M24 PF00557.24 EMR66008.1 - 4.4e-40 137.6 0.1 6.3e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EMR66008.1 - 2.5e-11 44.3 0.0 4.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Pectate_lyase PF03211.13 EMR66009.1 - 2.5e-83 278.6 4.2 3.3e-83 278.2 4.2 1.2 1 0 0 1 1 1 1 Pectate lyase AAA PF00004.29 EMR66010.1 - 7.6e-40 136.4 0.0 1.4e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EMR66010.1 - 5.1e-19 68.0 0.1 1e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EMR66010.1 - 3.3e-08 33.2 0.0 6.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EMR66010.1 - 9.3e-05 22.9 1.7 0.015 15.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EMR66010.1 - 0.00011 22.2 0.1 0.00051 20.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMR66010.1 - 0.00028 20.7 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR66010.1 - 0.00068 19.9 1.2 0.067 13.5 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 EMR66010.1 - 0.0014 18.8 0.0 0.008 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 EMR66010.1 - 0.0042 16.6 0.3 0.063 12.7 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EMR66010.1 - 0.0061 16.0 0.1 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EMR66010.1 - 0.0092 15.2 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EMR66010.1 - 0.013 15.6 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMR66010.1 - 0.063 13.0 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EMR66010.1 - 0.08 12.5 0.0 0.24 10.9 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EMR66010.1 - 0.11 12.2 0.0 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EMR66010.1 - 0.12 12.1 0.3 0.32 10.7 0.1 1.9 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EMR66010.1 - 0.2 11.2 0.7 1.2 8.6 0.2 2.2 1 1 1 2 2 2 0 AAA domain Acyl_transf_1 PF00698.21 EMR66012.1 - 6.1e-11 42.4 1.3 1e-05 25.3 1.2 2.1 1 1 1 2 2 2 2 Acyl transferase domain DUF2458 PF10454.9 EMR66012.1 - 0.0033 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Fungal_lectin PF07938.12 EMR66013.1 - 4.6e-08 32.8 0.9 8.5e-05 22.1 0.1 2.2 1 1 1 2 2 2 2 Fungal fucose-specific lectin Dehydrin PF00257.19 EMR66013.1 - 0.44 11.1 4.2 0.36 11.4 0.1 2.3 2 0 0 2 2 2 0 Dehydrin RRM_1 PF00076.22 EMR66014.1 - 1.2e-34 118.0 1.9 5.8e-17 61.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR66014.1 - 4.3e-10 39.6 0.1 0.00039 20.5 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EMR66014.1 - 6.1e-05 22.9 0.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EMR66014.1 - 0.071 13.2 0.0 20 5.3 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif TFIIA PF03153.13 EMR66014.1 - 0.41 10.6 23.3 0.58 10.1 23.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1631 PF07793.11 EMR66014.1 - 1.1 7.6 19.0 1.5 7.1 19.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Chorion_1 PF01723.16 EMR66015.1 - 0.014 15.4 1.8 0.018 15.0 1.8 1.2 1 0 0 1 1 1 0 Chorion protein MFS_1 PF07690.16 EMR66015.1 - 0.71 8.7 9.0 0.39 9.6 5.3 1.9 2 0 0 2 2 2 0 Major Facilitator Superfamily ADH_zinc_N PF00107.26 EMR66016.1 - 5.8e-11 42.5 0.1 1.3e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR66016.1 - 5.4e-06 26.3 0.1 2.2e-05 24.3 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EMR66016.1 - 0.0001 21.7 0.6 0.00015 21.1 0.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 EMR66016.1 - 0.00034 20.3 0.4 0.00057 19.5 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EMR66016.1 - 0.023 14.1 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase FAD_binding_2 PF00890.24 EMR66018.1 - 4.3e-95 319.3 0.4 4.9e-95 319.1 0.4 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR66018.1 - 8.8e-08 32.3 0.7 3.2e-07 30.5 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR66018.1 - 1e-07 31.7 0.1 2.1e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EMR66018.1 - 1e-07 31.9 6.7 5.4e-06 26.2 6.0 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMR66018.1 - 3.7e-07 29.7 0.5 3.7e-07 29.7 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EMR66018.1 - 9.1e-06 25.0 0.6 1.9e-05 24.0 0.6 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EMR66018.1 - 4.4e-05 22.8 4.4 0.00019 20.7 0.5 3.0 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR66018.1 - 0.0002 20.7 0.3 0.0005 19.4 0.3 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EMR66018.1 - 0.00022 21.7 0.6 0.042 14.4 0.4 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR66018.1 - 0.001 17.9 0.2 0.001 17.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EMR66018.1 - 0.0017 17.7 0.3 0.0031 16.8 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR66018.1 - 0.061 12.6 4.6 0.32 10.2 0.2 3.0 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase GMC_oxred_N PF00732.19 EMR66018.1 - 0.074 12.4 0.3 7.2 5.9 0.1 2.3 2 0 0 2 2 2 0 GMC oxidoreductase Lycopene_cycl PF05834.12 EMR66018.1 - 0.11 11.6 2.2 0.084 11.9 0.5 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein baeRF_family10 PF18854.1 EMR66018.1 - 0.12 12.6 1.8 0.21 11.9 0.3 2.2 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 10 Aminotran_4 PF01063.19 EMR66019.1 - 2.1e-25 89.9 0.0 2.6e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF2524 PF10732.9 EMR66020.1 - 0.013 15.8 5.2 0.47 10.8 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) NiFeSe_Hases PF00374.19 EMR66020.1 - 0.083 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase KHA PF11834.8 EMR66020.1 - 0.19 11.9 0.5 0.54 10.4 0.1 2.0 3 0 0 3 3 3 0 KHA, dimerisation domain of potassium ion channel INO80_Ies4 PF08193.11 EMR66021.1 - 1.8e-85 286.8 23.4 2.4e-85 286.4 23.4 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 DUF5127 PF17168.4 EMR66022.1 - 4.3e-84 281.8 2.3 6.2e-84 281.3 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EMR66022.1 - 3.9e-73 244.8 0.7 1.2e-72 243.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EMR66022.1 - 1.3e-65 220.9 1.2 2.9e-65 219.8 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EMR66022.1 - 2.9e-05 23.5 0.0 9.6e-05 21.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Mpp10 PF04006.12 EMR66023.1 - 9.5e-113 377.8 54.1 4.6e-112 375.5 54.1 2.0 1 1 0 1 1 1 1 Mpp10 protein Bac_luciferase PF00296.20 EMR66024.1 - 5.4e-54 183.7 1.0 5.4e-54 183.7 1.0 1.6 2 0 0 2 2 2 1 Luciferase-like monooxygenase Endonuc-PvuII PF09225.10 EMR66024.1 - 0.057 13.2 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease PvuII CTP_transf_like PF01467.26 EMR66025.1 - 6.3e-25 88.0 0.0 4e-21 75.7 0.0 3.0 3 0 0 3 3 3 2 Cytidylyltransferase-like ERG4_ERG24 PF01222.17 EMR66027.1 - 5e-143 477.0 21.8 5.9e-143 476.7 21.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family FXR_C1 PF16096.5 EMR66027.1 - 2.7 8.2 8.4 0.63 10.3 4.6 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DAO PF01266.24 EMR66028.1 - 2.7e-38 132.5 1.1 4.6e-38 131.7 1.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR66028.1 - 3.2e-05 23.3 0.0 6.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EMR66028.1 - 7.8e-05 22.8 0.4 0.00038 20.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 EMR66028.1 - 0.0038 15.9 0.0 0.0049 15.5 0.0 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 EMR66028.1 - 0.006 15.7 6.9 0.011 14.8 1.3 2.4 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR66028.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3446 PF11928.8 EMR66028.1 - 0.036 14.4 11.4 0.049 13.9 0.8 3.3 3 0 0 3 3 3 0 Early growth response N-terminal domain FAD_binding_3 PF01494.19 EMR66028.1 - 0.049 12.9 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EMR66028.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein RabGAP-TBC PF00566.18 EMR66029.1 - 1.2e-45 155.8 0.1 1.7e-45 155.3 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SSF PF00474.17 EMR66030.1 - 2.4e-21 76.1 28.6 4e-21 75.3 28.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family PhyH PF05721.13 EMR66031.1 - 4.8e-57 193.6 0.0 7e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EMR66031.1 - 0.098 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.16 EMR66032.1 - 6.4e-41 140.4 19.5 6.1e-40 137.2 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMR66032.1 - 4.2e-05 23.0 8.5 0.0001 21.8 2.7 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Neurensin PF14927.6 EMR66032.1 - 0.016 14.9 0.1 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 Neurensin DUF2776 PF10951.8 EMR66032.1 - 0.051 12.8 6.8 0.058 12.6 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2776) Ribosomal_L9_N PF01281.19 EMR66032.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain DUF3094 PF11293.8 EMR66032.1 - 0.063 13.0 0.9 3.1 7.6 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) TMEM100 PF16311.5 EMR66032.1 - 0.089 12.4 0.3 8.3 6.0 0.1 2.8 2 0 0 2 2 2 0 Transmembrane protein 100 EXS PF03124.14 EMR66032.1 - 2.6 7.3 7.4 0.38 10.0 1.3 2.4 3 0 0 3 3 3 0 EXS family Ank_2 PF12796.7 EMR66033.1 - 4.8e-14 52.7 0.6 1.9e-06 28.3 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR66033.1 - 1.5e-12 46.5 0.9 0.0013 19.1 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EMR66033.1 - 2e-11 43.9 3.7 0.00056 20.2 0.2 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EMR66033.1 - 4.7e-10 39.4 1.0 0.0064 16.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EMR66033.1 - 4.8e-09 36.6 0.8 0.0019 18.7 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PPR_2 PF13041.6 EMR66034.1 - 6.2e-13 48.7 0.0 1.6e-05 25.0 0.0 3.8 3 1 2 5 5 5 2 PPR repeat family PPR PF01535.20 EMR66034.1 - 4.5e-10 39.1 0.5 0.002 18.2 0.0 4.0 3 1 2 5 5 5 2 PPR repeat PPR_3 PF13812.6 EMR66034.1 - 8.8e-10 38.5 0.0 4.4e-05 23.5 0.0 3.4 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EMR66034.1 - 1.4e-09 37.5 0.0 4.5e-05 23.1 0.0 3.4 3 0 0 3 3 3 2 PPR repeat CorA PF01544.18 EMR66035.1 - 3.1e-09 36.6 0.3 4.3e-09 36.1 0.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CD225 PF04505.12 EMR66035.1 - 0.068 13.3 0.5 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF1539 PF07560.11 EMR66035.1 - 0.19 11.8 0.0 0.63 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Ceramidase_alk PF04734.13 EMR66036.1 - 3.6e-222 738.5 0.0 4.1e-222 738.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EMR66036.1 - 5.9e-53 179.2 0.1 1.3e-52 178.0 0.1 1.6 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Pkinase PF00069.25 EMR66038.1 - 2.3e-75 253.4 0.0 3.2e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR66038.1 - 9.1e-39 133.3 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EMR66038.1 - 6.5e-20 71.7 1.0 2.8e-11 43.9 0.2 2.5 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EMR66038.1 - 1.7e-16 60.0 0.3 5.3e-16 58.5 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EMR66038.1 - 3e-07 30.1 0.0 9.3e-07 28.4 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EMR66038.1 - 0.00085 18.4 0.1 0.0015 17.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EMR66038.1 - 0.00092 18.9 0.4 0.0018 17.9 0.4 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 EMR66038.1 - 0.0043 15.9 0.1 0.0067 15.3 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 EMR66038.1 - 0.055 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR66038.1 - 0.11 12.4 0.3 0.53 10.2 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Adap_comp_sub PF00928.21 EMR66039.1 - 8.9e-69 231.8 0.0 1.1e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMR66039.1 - 0.00052 20.0 0.0 0.00077 19.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain cNMP_binding PF00027.29 EMR66040.1 - 4.1e-38 129.3 0.0 2.8e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BNR_2 PF13088.6 EMR66041.1 - 1.1e-07 31.5 0.1 0.00042 19.7 0.0 2.6 3 0 0 3 3 3 2 BNR repeat-like domain BNR PF02012.20 EMR66041.1 - 0.14 12.3 2.1 0.5 10.6 2.1 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat CLTH PF10607.9 EMR66042.1 - 1.5e-33 115.8 0.1 2.3e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EMR66042.1 - 2.3e-23 82.6 0.2 4.4e-23 81.7 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EMR66042.1 - 3.3e-05 23.7 2.6 3.4e-05 23.6 0.1 2.4 3 0 0 3 3 3 1 LisH SMC_ScpB PF04079.16 EMR66042.1 - 0.017 14.8 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB BCAS2 PF05700.11 EMR66043.1 - 5.5e-58 196.1 6.5 6.3e-58 195.9 6.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Herpes_IE1 PF07340.11 EMR66044.1 - 0.044 12.7 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein tRNA_U5-meth_tr PF05958.11 EMR66045.1 - 2.7e-11 43.1 0.0 1.9e-09 37.0 0.0 3.0 3 1 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EMR66045.1 - 2.2e-05 25.1 0.0 7e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EMR66045.1 - 0.00035 20.2 0.0 0.00062 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 EMR66045.1 - 0.00052 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR66045.1 - 0.0081 16.8 0.0 0.032 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EMR66045.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UNC45-central PF11701.8 EMR66046.1 - 2.6e-52 176.9 0.2 2.7e-51 173.5 0.0 2.9 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Rcd1 PF04078.13 EMR66046.1 - 0.029 13.7 0.3 1.1 8.5 0.0 3.0 3 0 0 3 3 3 0 Cell differentiation family, Rcd1-like Arm PF00514.23 EMR66046.1 - 0.13 12.4 17.4 13 6.0 0.0 8.3 10 1 1 11 11 11 0 Armadillo/beta-catenin-like repeat DUF3730 PF12530.8 EMR66046.1 - 0.17 11.4 2.3 1.4 8.5 1.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 EMR66046.1 - 1 9.8 18.2 0.91 10.0 2.0 5.2 3 2 3 6 6 6 0 HEAT repeats HEAT PF02985.22 EMR66046.1 - 7.2 7.2 8.7 1.1e+02 3.5 0.1 5.3 5 0 0 5 5 5 0 HEAT repeat G_glu_transpept PF01019.21 EMR66047.1 - 3.4e-159 530.9 1.3 4.6e-159 530.5 1.3 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1479 PF07350.12 EMR66048.1 - 9.7e-123 410.0 0.0 1.1e-122 409.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF4990 PF16380.5 EMR66048.1 - 0.19 11.9 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DHR10 PF18595.1 EMR66049.1 - 0.024 14.7 24.5 0.13 12.3 1.3 3.4 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain TMEM214 PF10151.9 EMR66049.1 - 0.048 12.1 0.6 0.076 11.5 0.6 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4407 PF14362.6 EMR66049.1 - 0.25 10.6 19.5 7.6 5.8 19.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) KIP1 PF07765.12 EMR66049.1 - 0.36 11.0 4.0 0.45 10.7 0.1 2.8 2 1 1 3 3 3 0 KIP1-like protein BLOC1_2 PF10046.9 EMR66049.1 - 1.6 9.1 12.7 0.066 13.5 1.1 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EMR66049.1 - 4.8 7.5 5.9 6.3 7.1 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 EMR66049.1 - 6 5.6 23.5 3.2 6.6 15.7 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein ATP_transf PF09830.9 EMR66050.1 - 7.2e-17 61.3 0.1 2.3e-16 59.7 0.2 1.8 2 0 0 2 2 2 1 ATP adenylyltransferase DUF456 PF04306.13 EMR66051.1 - 0.016 15.5 2.1 0.016 15.5 2.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF456) DUF308 PF03729.13 EMR66051.1 - 2.5 8.5 19.2 0.41 11.0 2.1 3.3 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) HET PF06985.11 EMR66053.1 - 3.9e-10 40.2 3.6 1e-07 32.4 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HTH_IclR PF09339.10 EMR66054.1 - 0.01 15.6 0.0 3.6 7.4 0.0 3.3 3 0 0 3 3 3 0 IclR helix-turn-helix domain YflT PF11181.8 EMR66055.1 - 0.001 19.5 0.8 0.001 19.5 0.8 2.0 2 0 0 2 2 2 1 Heat induced stress protein YflT LCD1 PF09798.9 EMR66055.1 - 0.16 10.4 0.5 0.25 9.8 0.5 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein HET PF06985.11 EMR66056.1 - 1.1e-26 94.0 0.0 1.9e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuc_L-PSP PF01042.21 EMR66058.1 - 1.4e-23 83.2 0.0 1.7e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP FMO-like PF00743.19 EMR66059.1 - 1.5e-14 53.4 0.0 1.4e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMR66059.1 - 5.3e-12 45.6 0.0 3.4e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR66059.1 - 2.9e-09 37.0 0.0 5.8e-08 32.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR66059.1 - 1.8e-07 31.1 0.0 0.0082 15.8 0.0 3.4 2 1 1 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR66059.1 - 5e-07 29.3 0.1 0.00018 20.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR66059.1 - 6.4e-07 29.5 0.2 4.3e-06 26.8 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EMR66059.1 - 1.5e-06 27.6 0.0 0.0001 21.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EMR66059.1 - 0.0003 20.1 0.0 0.00063 19.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 EMR66059.1 - 0.0031 16.8 0.0 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EMR66059.1 - 0.012 16.1 0.1 10 6.8 0.2 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR66059.1 - 0.037 13.3 0.1 0.086 12.1 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EMR66059.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein IMUP PF15761.5 EMR66059.1 - 3.2 8.5 6.5 6.5 7.5 6.5 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Nse5 PF08691.10 EMR66060.1 - 0.031 13.0 0.8 0.042 12.5 0.8 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 DUF334 PF03904.13 EMR66060.1 - 0.078 12.5 5.3 0.13 11.7 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) RHSP PF07999.11 EMR66060.1 - 0.27 10.0 2.7 0.5 9.1 0.4 2.0 2 0 0 2 2 2 0 Retrotransposon hot spot protein DUF948 PF06103.11 EMR66060.1 - 1.3 9.3 3.8 25 5.2 0.2 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4381 PF14316.6 EMR66060.1 - 5.6 7.2 8.6 1.3 9.2 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4618 PF15397.6 EMR66060.1 - 6.5 6.1 21.2 0.079 12.4 8.6 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) Glyco_transf_90 PF05686.12 EMR66061.1 - 2.8e-25 89.0 1.8 3.9e-25 88.6 1.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EMR66061.1 - 0.0021 18.4 0.2 0.0051 17.2 0.2 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 SF3b1 PF08920.10 EMR66061.1 - 0.074 13.6 0.1 0.3 11.6 0.0 2.0 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 2-Hacid_dh_C PF02826.19 EMR66062.1 - 1.6e-53 180.7 0.0 2.3e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR66062.1 - 6.9e-33 113.2 0.0 8.2e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMR66062.1 - 0.0019 18.4 0.0 0.0077 16.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sulfatase PF00884.23 EMR66063.1 - 1.5e-60 205.2 0.8 2e-60 204.8 0.8 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EMR66063.1 - 0.056 12.1 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TFR_dimer PF04253.15 EMR66064.1 - 8e-25 87.3 0.0 1.4e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EMR66064.1 - 1.3e-20 73.9 0.0 2.2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMR66064.1 - 6.7e-06 26.0 1.4 1.5e-05 24.9 0.2 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EMR66064.1 - 0.0087 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 adh_short_C2 PF13561.6 EMR66065.1 - 1.6e-52 178.4 0.0 2.3e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR66065.1 - 1.2e-45 155.4 0.0 1.9e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase FAD_binding_3 PF01494.19 EMR66065.1 - 5.6e-20 71.9 3.1 2.3e-10 40.3 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain DUF1776 PF08643.10 EMR66065.1 - 6.3e-05 22.5 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EMR66065.1 - 0.00034 20.6 0.0 0.00069 19.6 0.0 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMR66065.1 - 0.00034 20.5 0.0 0.17 11.8 0.0 2.6 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EMR66065.1 - 0.00039 20.6 0.2 0.0037 17.5 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EMR66065.1 - 0.0035 17.6 0.0 0.39 11.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.16 EMR66065.1 - 0.0064 16.1 0.0 4.7 6.8 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 EMR66065.1 - 0.0074 15.8 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 EMR66065.1 - 0.0083 15.4 0.0 0.027 13.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR66065.1 - 0.019 14.2 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR66065.1 - 0.033 13.8 0.3 1.6 8.2 0.0 2.6 2 1 0 3 3 3 0 FAD dependent oxidoreductase GDP_Man_Dehyd PF16363.5 EMR66065.1 - 0.055 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMR66065.1 - 0.074 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_16 PF10294.9 EMR66067.1 - 5.4e-26 91.4 0.1 8.2e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EMR66067.1 - 3.7e-08 33.1 0.0 5.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EMR66067.1 - 1.1e-06 29.2 0.2 2.4e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR66067.1 - 1.2e-06 28.2 0.1 1.9e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EMR66067.1 - 8.1e-06 26.5 0.1 1.3e-05 25.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR66067.1 - 4.2e-05 23.4 0.0 5.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EMR66067.1 - 0.0016 18.3 0.0 0.0098 15.7 0.0 1.9 1 1 0 2 2 2 1 Met-10+ like-protein Methyltransf_23 PF13489.6 EMR66067.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EMR66067.1 - 0.0038 16.9 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RrnaAD PF00398.20 EMR66067.1 - 0.0084 15.2 0.0 0.027 13.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 EMR66067.1 - 0.026 15.2 0.1 0.058 14.0 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EMR66067.1 - 0.1 12.3 0.1 0.3 10.8 0.1 1.8 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Esterase_phd PF10503.9 EMR66069.1 - 3.1e-07 30.1 2.1 6.1e-07 29.1 2.1 1.6 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMR66069.1 - 0.0015 18.1 0.3 0.0053 16.3 0.3 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EMR66069.1 - 0.0018 17.0 0.3 0.0054 15.5 0.3 1.7 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 EMR66069.1 - 0.051 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 EMR66069.1 - 0.062 12.9 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF3558 PF12079.8 EMR66070.1 - 0.00095 19.2 1.1 0.0011 19.0 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) SSP160 PF06933.11 EMR66070.1 - 0.01 14.1 12.9 0.013 13.7 12.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EMR66070.1 - 0.066 13.2 6.8 0.096 12.7 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EMR66070.1 - 0.55 8.1 1.5 0.65 7.9 1.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Asp PF00026.23 EMR66071.1 - 2e-44 152.3 6.9 6.4e-33 114.5 2.8 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR66071.1 - 8.6e-14 52.2 0.2 1.3e-12 48.4 0.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Macoilin PF09726.9 EMR66072.1 - 0.099 11.2 9.8 0.12 10.9 9.8 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_61 PF03443.14 EMR66073.1 - 2.1e-55 187.9 0.2 2.5e-55 187.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAR2 PF16974.5 EMR66073.1 - 0.039 13.4 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory DUF5624 PF18538.1 EMR66073.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) MG2 PF01835.19 EMR66073.1 - 0.098 13.1 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 MG2 domain tRNA-synt_1c PF00749.21 EMR66074.1 - 5.2e-98 327.8 0.0 6.9e-98 327.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EMR66074.1 - 5e-29 101.4 0.0 1.5e-28 99.8 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Sugar_tr PF00083.24 EMR66075.1 - 2.9e-77 260.5 19.1 3.6e-77 260.2 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66075.1 - 3.1e-18 65.8 41.4 9.1e-17 61.0 22.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NPP1 PF05630.11 EMR66076.1 - 2.2e-65 220.5 0.0 2.6e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) CN_hydrolase PF00795.22 EMR66078.1 - 2.7e-27 95.8 0.1 3.6e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_3 PF01494.19 EMR66079.1 - 3.4e-26 92.3 0.0 6.7e-26 91.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR66079.1 - 0.034 13.4 0.1 0.34 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR66079.1 - 0.087 13.1 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 EMR66079.1 - 0.13 11.3 0.0 0.3 10.1 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 EMR66079.1 - 0.77 9.3 2.3 1.6 8.3 1.8 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_61 PF03443.14 EMR66080.1 - 5.2e-43 147.4 0.4 5.8e-43 147.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cgr1 PF03879.14 EMR66083.1 - 3.2e-21 75.7 30.6 3.4e-21 75.6 30.6 1.0 1 0 0 1 1 1 1 Cgr1 family Snapin_Pallidin PF14712.6 EMR66084.1 - 0.014 15.8 1.4 0.031 14.7 1.4 1.6 1 0 0 1 1 1 0 Snapin/Pallidin ZapB PF06005.12 EMR66084.1 - 0.018 15.5 6.2 0.16 12.4 1.1 2.5 1 1 1 2 2 2 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 EMR66084.1 - 0.029 14.6 1.7 0.046 14.0 1.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF16 PF01519.16 EMR66084.1 - 0.032 14.7 2.0 0.076 13.5 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EMR66084.1 - 0.04 14.1 0.9 0.25 11.5 0.8 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EMR66084.1 - 0.052 12.4 4.1 0.12 11.2 4.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 EMR66084.1 - 0.058 13.7 1.8 0.82 10.0 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Med4 PF10018.9 EMR66084.1 - 0.058 13.1 0.7 0.45 10.2 0.1 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 eIF3_N PF09440.10 EMR66084.1 - 0.099 13.1 1.2 0.11 12.9 0.3 1.6 2 0 0 2 2 1 0 eIF3 subunit 6 N terminal domain WASH_WAHD PF11945.8 EMR66084.1 - 0.13 11.8 0.7 0.21 11.1 0.5 1.5 1 1 0 1 1 1 0 WAHD domain of WASH complex DUF1664 PF07889.12 EMR66084.1 - 0.14 12.2 1.4 1.6 8.8 1.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ABC2_membrane_2 PF12679.7 EMR66084.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein GAS PF13851.6 EMR66084.1 - 0.17 11.2 2.5 0.26 10.6 2.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 EMR66084.1 - 0.29 9.6 0.6 0.35 9.4 0.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family VAPB_antitox PF02697.14 EMR66084.1 - 0.31 11.8 2.5 5.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Putative antitoxin TolA_bind_tri PF16331.5 EMR66084.1 - 0.34 11.0 4.2 0.97 9.5 4.1 1.9 1 1 0 1 1 1 0 TolA binding protein trimerisation BST2 PF16716.5 EMR66084.1 - 0.67 10.6 3.5 1.8 9.2 0.4 2.5 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 Med9 PF07544.13 EMR66084.1 - 2.4 8.3 4.9 12 6.1 2.6 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 EMR66084.1 - 3.7 8.2 5.6 3 8.5 1.8 2.5 2 1 0 2 2 2 0 SlyX Seryl_tRNA_N PF02403.22 EMR66084.1 - 4.3 7.6 6.5 20 5.5 2.0 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FAD_binding_2 PF00890.24 EMR66085.1 - 2.6e-124 415.5 2.3 3.1e-124 415.2 2.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EMR66085.1 - 6.9e-43 145.7 0.2 1e-42 145.1 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 EMR66085.1 - 1.6e-05 24.3 0.1 0.0061 15.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EMR66085.1 - 0.00027 20.1 0.7 0.046 12.8 1.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EMR66085.1 - 0.00034 20.0 0.8 0.04 13.2 0.1 2.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR66085.1 - 0.0091 15.3 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMR66085.1 - 0.22 10.2 0.7 0.68 8.6 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF3818 PF12825.7 EMR66086.1 - 4.6e-129 430.3 5.2 7e-129 429.7 5.2 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EMR66086.1 - 1.2e-39 135.3 0.3 2.5e-39 134.2 0.3 1.6 1 0 0 1 1 1 1 PX-associated DUF3381 PF11861.8 EMR66086.1 - 0.0025 17.6 2.3 0.0093 15.8 2.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) PX PF00787.24 EMR66086.1 - 0.0031 17.5 3.3 0.19 11.7 1.2 3.1 2 1 0 2 2 2 1 PX domain Myc_N PF01056.18 EMR66086.1 - 0.1 12.5 1.0 0.18 11.7 1.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Cwf_Cwc_15 PF04889.12 EMR66086.1 - 5.4 6.7 14.8 0.049 13.3 6.0 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein UQ_con PF00179.26 EMR66087.1 - 5.6e-29 100.6 0.0 6.9e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CAF1-p150_C2 PF15539.6 EMR66087.1 - 0.049 13.1 0.3 0.087 12.3 0.3 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term DUF3433 PF11915.8 EMR66088.1 - 6.4e-09 36.2 0.6 1.7e-08 34.8 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Caveolin PF01146.17 EMR66088.1 - 0.091 12.7 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Caveolin MFS_1 PF07690.16 EMR66089.1 - 3.6e-30 105.1 22.5 7.7e-30 104.0 22.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 EMR66091.1 - 2.8e-56 190.7 0.2 3.3e-56 190.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR66091.1 - 1.9e-45 154.7 0.0 2.4e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR66091.1 - 3.5e-05 23.8 0.0 0.00034 20.6 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMR66091.1 - 0.0062 16.0 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR66091.1 - 0.0083 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TFB6 PF17110.5 EMR66092.1 - 2.4e-48 164.1 21.7 4.8e-43 146.9 0.1 3.2 1 1 0 2 2 2 2 Subunit 11 of the general transcription factor TFIIH DUF4551 PF15087.6 EMR66092.1 - 0.15 10.9 5.5 0.2 10.5 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-CCHC PF00098.23 EMR66093.1 - 4.3e-47 156.2 59.7 5.9e-08 32.4 2.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EMR66093.1 - 1.3e-10 40.8 38.6 0.16 11.7 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 EMR66093.1 - 2.6e-07 30.5 41.7 0.011 15.7 0.0 6.9 4 2 3 7 7 7 5 Zinc knuckle zf-CCHC_5 PF14787.6 EMR66093.1 - 1e-05 25.1 43.7 0.0069 16.1 1.0 7.0 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EMR66093.1 - 0.034 14.0 49.3 0.06 13.2 0.2 6.8 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.6 EMR66093.1 - 0.059 13.2 2.0 0.059 13.2 2.0 7.2 7 0 0 7 7 7 0 Zinc knuckle Sporozoite_P67 PF05642.11 EMR66093.1 - 1.1 7.2 4.7 1.1 7.2 4.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_16 PF00722.21 EMR66094.1 - 8.6e-13 48.1 0.0 1.4e-12 47.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EMR66094.1 - 9.8e-08 30.8 0.1 0.0043 15.5 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Lipocalin_4 PF13648.6 EMR66094.1 - 0.024 15.6 2.9 0.57 11.2 0.2 2.2 2 0 0 2 2 2 0 Lipocalin-like domain Asparaginase_2 PF01112.18 EMR66094.1 - 0.075 12.1 0.2 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 Asparaginase Abhydrolase_6 PF12697.7 EMR66097.1 - 4e-12 47.2 0.0 8.1e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR66097.1 - 1.5e-07 31.0 0.0 2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMR66097.1 - 0.044 12.5 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 EMR66097.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Sulfatase PF00884.23 EMR66098.1 - 1.6e-75 254.4 0.0 1.9e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 EMR66098.1 - 6.6e-05 23.6 0.5 0.0015 19.3 0.1 2.5 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 EMR66098.1 - 0.0037 17.5 0.0 0.0093 16.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 EMR66098.1 - 0.037 12.6 0.0 0.057 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Phosphodiest PF01663.22 EMR66098.1 - 0.044 13.4 0.0 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase adh_short PF00106.25 EMR66099.1 - 2.1e-21 76.3 0.0 3.1e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66099.1 - 3.9e-13 49.5 0.0 5.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66099.1 - 1.5e-05 25.0 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR66099.1 - 0.0065 16.0 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR66099.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CRISPR_Cas2 PF09827.9 EMR66099.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 CRISPR associated protein Cas2 THF_DHG_CYH_C PF02882.19 EMR66099.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 EMR66099.1 - 0.23 10.5 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1751 PF08551.10 EMR66100.1 - 8.1e-05 23.1 0.7 0.00017 22.1 0.7 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Gly-zipper_Omp PF13488.6 EMR66100.1 - 0.14 12.1 0.3 0.33 11.0 0.3 1.5 1 0 0 1 1 1 0 Glycine zipper Sugar_tr PF00083.24 EMR66102.1 - 0.0058 15.5 4.8 0.011 14.6 4.8 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66102.1 - 0.27 10.1 14.4 0.13 11.2 10.8 1.9 2 0 0 2 2 2 0 Major Facilitator Superfamily HET PF06985.11 EMR66103.1 - 7.7e-23 81.5 1.8 7.7e-23 81.5 1.8 2.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 EMR66103.1 - 1.6e-15 57.7 0.0 5.8e-15 55.9 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR66103.1 - 0.00046 20.6 0.1 0.0025 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMR66103.1 - 0.0021 18.3 0.1 0.016 15.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EMR66103.1 - 0.017 15.1 0.1 0.17 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EMR66103.1 - 0.058 13.0 0.5 0.36 10.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain Vps36_ESCRT-II PF11605.8 EMR66103.1 - 0.071 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Zeta_toxin PF06414.12 EMR66103.1 - 0.12 11.6 0.1 0.86 8.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EMR66103.1 - 0.15 12.6 0.2 0.77 10.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EMR66103.1 - 0.24 11.6 0.9 0.58 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Ank_5 PF13857.6 EMR66104.1 - 8.5e-20 70.6 1.4 3.6e-05 23.9 0.0 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR66104.1 - 2.4e-19 69.7 0.0 4e-09 36.9 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR66104.1 - 1.4e-16 60.6 1.2 0.00073 20.0 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EMR66104.1 - 2e-15 56.4 4.0 0.00016 22.0 0.2 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EMR66104.1 - 2.7e-15 54.9 5.4 0.002 18.5 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Clp_N PF02861.20 EMR66104.1 - 0.13 12.5 0.5 24 5.2 0.0 2.7 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component GST_C_3 PF14497.6 EMR66105.1 - 1.1e-25 89.7 0.0 1.9e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMR66105.1 - 0.00034 20.9 0.0 0.0022 18.3 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR66105.1 - 0.0009 19.2 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR66105.1 - 0.0023 18.1 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PilJ PF13675.6 EMR66105.1 - 0.092 12.8 0.2 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Glyco_hydro_76 PF03663.14 EMR66106.1 - 0.00083 19.0 0.0 0.00099 18.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 adh_short PF00106.25 EMR66107.1 - 2.2e-12 46.9 0.0 1.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66107.1 - 9.4e-07 28.6 0.0 3.4e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Uds1 PF15456.6 EMR66108.1 - 2.1e-30 105.5 3.2 2.1e-30 105.5 3.2 5.2 4 1 1 5 5 5 1 Up-regulated During Septation Spc7 PF08317.11 EMR66108.1 - 0.00062 18.8 49.8 0.0017 17.3 22.3 4.4 2 1 1 3 3 3 2 Spc7 kinetochore protein DUF4164 PF13747.6 EMR66108.1 - 0.0021 18.3 10.6 0.0021 18.3 10.6 6.8 6 2 2 8 8 8 1 Domain of unknown function (DUF4164) HR1 PF02185.16 EMR66108.1 - 0.0038 17.3 1.9 0.0038 17.3 1.9 7.7 6 2 3 9 9 9 3 Hr1 repeat FliJ PF02050.16 EMR66108.1 - 0.011 16.0 20.5 0.011 16.0 20.5 6.1 4 2 2 6 6 6 0 Flagellar FliJ protein Fez1 PF06818.15 EMR66108.1 - 0.015 15.8 14.2 0.015 15.8 14.2 4.3 2 1 2 4 4 4 0 Fez1 Lectin_N PF03954.14 EMR66108.1 - 3 7.6 14.5 2.5 7.9 0.3 5.0 4 1 1 5 5 5 0 Hepatic lectin, N-terminal domain Cep3 PF16846.5 EMR66108.1 - 3.6 5.9 6.7 0.64 8.4 2.5 1.8 2 0 0 2 2 2 0 Centromere DNA-binding protein complex CBF3 subunit B Vps53_N PF04100.12 EMR66108.1 - 5 6.0 13.7 0.19 10.7 7.0 2.0 2 0 0 2 2 2 0 Vps53-like, N-terminal Matrilin_ccoil PF10393.9 EMR66108.1 - 6.4 6.7 9.7 7.8 6.5 0.8 4.4 5 1 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin PHD PF00628.29 EMR66109.1 - 3.1e-06 27.0 7.5 5.4e-06 26.2 7.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EMR66109.1 - 0.0024 17.4 2.0 0.0041 16.6 2.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EMR66109.1 - 0.022 15.0 2.8 0.061 13.6 2.8 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain Epimerase PF01370.21 EMR66110.1 - 0.00017 21.2 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR66110.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 EMR66110.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Pyr_redox_2 PF07992.14 EMR66111.1 - 4.1e-05 23.0 0.1 7.1e-05 22.2 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR66111.1 - 0.00079 18.8 0.2 0.011 15.0 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase His_Phos_2 PF00328.22 EMR66112.1 - 3e-37 128.9 0.0 1e-18 67.9 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) V_ATPase_I PF01496.19 EMR66113.1 - 0 1052.7 0.0 0 1052.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 EMR66113.1 - 0.085 12.4 4.6 0.89 9.1 0.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 EMR66113.1 - 0.12 11.8 8.3 0.55 9.6 0.3 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 SesA PF17107.5 EMR66113.1 - 0.22 11.7 1.9 0.86 9.8 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CheZ PF04344.13 EMR66113.1 - 0.26 11.2 4.9 0.27 11.1 0.6 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Laminin_II PF06009.12 EMR66113.1 - 0.42 10.6 5.4 6.3 6.8 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 EMR66113.1 - 0.48 10.5 5.6 2 8.5 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EMR66113.1 - 0.52 9.1 6.4 1.5 7.6 0.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.9 EMR66113.1 - 0.53 9.1 4.0 1.6 7.5 0.6 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Baculo_PEP_C PF04513.12 EMR66113.1 - 0.72 9.9 6.4 2.5 8.1 1.3 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup54 PF13874.6 EMR66113.1 - 0.75 9.9 5.3 2.3 8.3 0.3 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 EzrA PF06160.12 EMR66113.1 - 1.1 7.4 10.2 1.1 7.4 1.9 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Filament PF00038.21 EMR66113.1 - 1.1 8.8 14.2 0.19 11.2 1.0 2.6 2 1 0 2 2 2 0 Intermediate filament protein HMMR_N PF15905.5 EMR66113.1 - 1.4 8.3 9.2 0.87 9.0 1.5 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FapA PF03961.13 EMR66113.1 - 3.9 6.0 5.0 2.4 6.7 0.4 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DivIC PF04977.15 EMR66113.1 - 4.8 7.0 11.9 0.22 11.3 1.1 3.3 2 1 1 3 3 3 0 Septum formation initiator DUF4140 PF13600.6 EMR66113.1 - 5 7.6 6.1 10 6.6 0.9 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Peptidase_S9 PF00326.21 EMR66114.1 - 4.8e-11 42.5 0.0 2.1e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EMR66114.1 - 0.0015 18.5 0.1 0.0067 16.3 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EMR66114.1 - 0.016 15.3 0.0 0.05 13.7 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 EMR66114.1 - 0.051 13.1 0.0 7.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family IMUP PF15761.5 EMR66114.1 - 1.6 9.5 10.5 0.44 11.3 2.4 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein RIP PF00161.19 EMR66115.1 - 1.6e-44 151.8 0.1 2.6e-44 151.1 0.1 1.4 1 0 0 1 1 1 1 Ribosome inactivating protein Fungal_lectin_2 PF18647.1 EMR66116.1 - 0.048 14.1 0.1 0.094 13.2 0.1 1.5 1 1 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin FAD_binding_4 PF01565.23 EMR66117.1 - 8.4e-25 87.1 0.7 1.3e-24 86.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR66117.1 - 1.6e-07 31.3 0.0 2.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Acetyltransf_1 PF00583.25 EMR66118.1 - 1.8e-05 24.9 0.0 2.9e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR66118.1 - 2.3e-05 24.7 0.0 4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR66118.1 - 0.0031 17.5 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EMR66118.1 - 0.05 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 EMR66118.1 - 0.095 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Prenyltransf PF01255.19 EMR66119.1 - 3.4e-80 268.8 0.0 5.2e-80 268.2 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase zf-C2H2 PF00096.26 EMR66120.1 - 0.06 13.8 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 EMR66120.1 - 0.071 13.7 0.9 0.13 12.9 0.6 1.6 1 1 1 2 2 2 0 FOXP coiled-coil domain NARP1 PF12569.8 EMR66120.1 - 2.2 7.1 7.9 2.7 6.8 7.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3987 PF13148.6 EMR66120.1 - 2.3 7.1 9.4 3 6.8 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) 5-FTHF_cyc-lig PF01812.20 EMR66121.1 - 5.7e-13 49.1 0.0 7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GTP_EFTU PF00009.27 EMR66122.1 - 1.9e-68 229.9 0.3 2.7e-68 229.4 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EMR66122.1 - 3.4e-32 110.8 0.0 1.1e-31 109.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EMR66122.1 - 3.1e-21 75.2 0.0 4.5e-20 71.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMR66122.1 - 1.5e-13 50.9 0.6 4.5e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EMR66122.1 - 3.6e-12 46.2 0.0 1.3e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EMR66122.1 - 0.00044 20.3 0.3 0.0011 19.0 0.3 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR66122.1 - 0.21 11.5 1.6 2.5 8.0 0.3 2.6 2 1 0 2 2 2 0 RsgA GTPase DAGK_cat PF00781.24 EMR66123.1 - 4e-07 29.7 0.0 1.5e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain TRM PF02005.16 EMR66124.1 - 1.3e-101 340.6 0.0 2.2e-99 333.2 0.0 2.4 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DUF2378 PF09536.10 EMR66124.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2378) Methyltransf_25 PF13649.6 EMR66124.1 - 0.0065 17.1 0.0 0.019 15.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EMR66124.1 - 0.0086 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.16 EMR66124.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 EMR66124.1 - 0.062 12.8 0.0 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_15 PF09445.10 EMR66124.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase XRN_M PF17846.1 EMR66124.1 - 0.29 10.0 2.8 0.61 9.0 2.8 1.4 1 0 0 1 1 1 0 Xrn1 helical domain LSM PF01423.22 EMR66125.1 - 4.8e-15 55.0 0.1 5.5e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EMR66125.1 - 0.0041 16.7 0.1 0.0061 16.2 0.1 1.3 1 0 0 1 1 1 1 Hfq protein SLATT_fungal PF18142.1 EMR66126.1 - 4.6e-26 91.2 0.0 6.5e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain DUF4231 PF14015.6 EMR66126.1 - 0.022 15.2 1.1 0.071 13.6 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ABC_tran PF00005.27 EMR66127.1 - 3.6e-37 127.9 10.2 1.5e-22 80.6 0.0 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EMR66127.1 - 2.4e-10 40.7 8.3 0.0047 16.8 0.8 3.8 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMR66127.1 - 4.5e-10 39.1 0.5 0.0013 18.5 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EMR66127.1 - 3e-07 30.5 0.4 0.015 15.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EMR66127.1 - 2.4e-06 27.9 0.5 0.0018 18.5 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMR66127.1 - 4e-06 27.4 1.1 0.043 14.4 0.0 3.4 3 2 0 3 3 2 2 AAA domain AAA_16 PF13191.6 EMR66127.1 - 2.8e-05 24.5 5.8 0.02 15.3 0.4 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_tran_Xtn PF12848.7 EMR66127.1 - 5.2e-05 23.2 5.1 5.2e-05 23.2 5.1 2.4 2 1 1 3 3 2 1 ABC transporter MeaB PF03308.16 EMR66127.1 - 5.4e-05 22.3 0.8 0.081 11.9 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EMR66127.1 - 7e-05 22.8 5.3 0.033 14.1 0.2 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EMR66127.1 - 0.0001 22.6 1.8 0.62 10.3 0.1 3.3 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 EMR66127.1 - 0.00013 22.4 0.2 0.028 14.8 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EMR66127.1 - 0.00014 21.8 0.1 0.08 12.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 EMR66127.1 - 0.00019 21.6 12.1 0.069 13.2 0.1 3.6 3 1 0 3 3 3 2 Helicase HerA, central domain AAA_30 PF13604.6 EMR66127.1 - 0.00024 20.9 3.6 0.43 10.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.19 EMR66127.1 - 0.00049 19.6 8.5 0.85 9.0 0.0 4.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 EMR66127.1 - 0.00072 19.6 1.7 0.21 11.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EMR66127.1 - 0.0016 18.8 0.1 0.39 11.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 EMR66127.1 - 0.0026 17.7 1.1 0.07 13.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EMR66127.1 - 0.0029 16.8 2.3 0.35 10.0 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EMR66127.1 - 0.0059 16.6 4.9 0.19 11.6 0.1 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EMR66127.1 - 0.0065 16.2 0.0 1.8 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 EMR66127.1 - 0.011 15.1 0.7 0.53 9.7 0.1 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family NTPase_1 PF03266.15 EMR66127.1 - 0.013 15.4 0.2 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 NTPase ATP-synt_ab PF00006.25 EMR66127.1 - 0.014 15.1 0.3 6.4 6.4 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Thymidylate_kin PF02223.17 EMR66127.1 - 0.014 15.1 2.6 3.1 7.4 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase Viral_helicase1 PF01443.18 EMR66127.1 - 0.016 14.9 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EMR66127.1 - 0.023 14.2 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_ATPase PF09818.9 EMR66127.1 - 0.025 13.4 0.6 0.14 10.9 0.0 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 EMR66127.1 - 0.031 14.5 7.6 0.4 10.8 0.0 3.2 4 1 0 4 4 2 0 AAA domain Roc PF08477.13 EMR66127.1 - 0.036 14.3 2.3 6.7 7.0 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 EMR66127.1 - 0.049 14.1 8.3 4.2 7.8 0.0 4.0 3 1 0 4 4 4 0 AAA domain NB-ARC PF00931.22 EMR66127.1 - 0.052 12.7 6.5 3.3 6.8 0.0 3.9 4 0 0 4 4 4 0 NB-ARC domain AAA_27 PF13514.6 EMR66127.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.9 4 0 0 4 4 2 0 AAA domain TsaE PF02367.17 EMR66127.1 - 0.17 11.9 0.6 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 EMR66127.1 - 0.2 11.7 8.7 9 6.3 3.6 3.5 3 1 0 3 3 3 0 Dynamin family MobB PF03205.14 EMR66127.1 - 0.37 10.7 2.4 8.4 6.3 0.1 3.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.20 EMR66127.1 - 0.8 8.8 5.9 2.6 7.1 0.8 2.7 2 1 0 2 2 2 0 G-protein alpha subunit cobW PF02492.19 EMR66127.1 - 2.4 7.7 4.6 12 5.5 0.3 2.7 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EMR66127.1 - 4.4 7.8 38.5 0.93 10.0 0.2 4.1 2 1 0 2 2 1 0 AAA domain Xpo1 PF08389.12 EMR66128.1 - 1.2e-30 106.5 4.9 2.1e-30 105.7 0.5 3.6 4 2 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 EMR66128.1 - 8.4e-05 22.4 0.1 0.00026 20.8 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain GAT PF03127.14 EMR66128.1 - 0.0039 17.5 1.3 0.017 15.4 0.2 2.8 4 0 0 4 4 4 1 GAT domain Ribosomal_S5_C PF03719.15 EMR66128.1 - 0.044 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain DUF3865 PF12981.7 EMR66128.1 - 0.089 12.7 0.1 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3865) Importin_rep_3 PF18806.1 EMR66128.1 - 0.14 12.3 0.0 3.7 7.6 0.0 3.0 2 0 0 2 2 2 0 Importin 13 repeat Adaptin_N PF01602.20 EMR66128.1 - 0.25 9.9 3.5 0.65 8.5 0.5 2.8 3 0 0 3 3 3 0 Adaptin N terminal region AMP-binding PF00501.28 EMR66129.1 - 2.6e-66 224.0 0.2 8.4e-25 87.2 0.0 4.9 4 1 1 5 5 5 4 AMP-binding enzyme DMAP_binding PF06464.11 EMR66129.1 - 2.8e-10 41.0 0.0 1.3e-09 38.8 0.0 2.0 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 EMR66129.1 - 0.026 14.5 0.7 0.079 13.0 0.7 1.8 1 0 0 1 1 1 0 Gas vesicle protein G PDEase_II PF02112.15 EMR66130.1 - 6.8e-25 87.9 0.0 8.5e-18 64.5 0.0 2.0 2 0 0 2 2 2 2 cAMP phosphodiesterases class-II CN_hydrolase PF00795.22 EMR66131.1 - 2.8e-47 161.3 0.0 3.6e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 EMR66132.1 - 5.8e-13 48.5 30.7 5.8e-13 48.5 30.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR66132.1 - 1.6e-09 37.7 4.6 1.6e-09 37.7 4.6 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Peptidase_M48_N PF16491.5 EMR66132.1 - 1.4 8.8 15.7 0.7 9.8 0.1 3.7 4 1 0 4 4 4 0 CAAX prenyl protease N-terminal, five membrane helices Glyco_hydro_3_C PF01915.22 EMR66133.1 - 1.5e-49 168.7 0.0 2.8e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR66133.1 - 3.9e-41 141.5 0.0 6.3e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Peptidase_C48 PF02902.19 EMR66134.1 - 2e-07 31.1 0.0 2.1e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Flavin_Reduct PF01613.18 EMR66135.1 - 1.8e-18 67.1 0.1 2.5e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Pkinase_Tyr PF07714.17 EMR66136.1 - 0.0019 17.5 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EMR66136.1 - 0.014 14.8 0.0 0.23 10.8 0.0 2.5 2 1 1 3 3 3 0 Protein kinase domain SMP_LBD PF17047.5 EMR66136.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain VPS38 PF17649.1 EMR66136.1 - 0.094 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Glyco_hydro_61 PF03443.14 EMR66139.1 - 9.5e-48 162.8 0.0 1.2e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4469 PF14734.6 EMR66139.1 - 0.071 13.3 0.0 0.2 11.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold TauD PF02668.16 EMR66141.1 - 9.6e-36 123.9 0.1 1.5e-35 123.3 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EMR66142.1 - 2.3e-07 30.1 34.0 2.3e-07 30.1 34.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR66142.1 - 6.3e-06 26.0 4.9 6.3e-06 26.0 4.9 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Lactamase_B_4 PF13691.6 EMR66143.1 - 2.4e-26 91.2 0.0 1.7e-25 88.5 0.1 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EMR66143.1 - 1.9e-14 53.6 1.0 9.2e-14 51.4 1.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMR66143.1 - 8e-07 29.3 4.4 2e-05 24.7 4.4 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_16 PF00722.21 EMR66144.1 - 2.6e-07 30.3 0.2 5.4e-07 29.2 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 C1-set PF07654.15 EMR66144.1 - 0.059 13.8 0.2 0.28 11.6 0.0 2.1 1 1 1 2 2 2 0 Immunoglobulin C1-set domain Epimerase PF01370.21 EMR66145.1 - 4.6e-12 45.9 0.1 3.1e-11 43.2 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR66145.1 - 1.5e-09 37.3 0.0 2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMR66145.1 - 7.5e-09 35.4 0.0 1.3e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMR66145.1 - 1.5e-06 27.6 0.1 3.6e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EMR66145.1 - 2.4e-06 26.9 0.0 1.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMR66145.1 - 3.4e-06 27.1 0.0 5.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EMR66145.1 - 0.013 14.9 0.1 0.055 12.9 0.0 1.9 2 1 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 EMR66145.1 - 0.036 13.6 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 EMR66145.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lyase_aromatic PF00221.19 EMR66146.1 - 8.6e-150 499.4 3.2 9.7e-150 499.3 3.2 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase UbiA PF01040.18 EMR66147.1 - 2.4e-33 115.5 13.7 3.5e-33 115.0 13.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_3 PF01494.19 EMR66148.1 - 2.3e-23 83.0 0.0 1.1e-22 80.8 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR66148.1 - 1.8e-08 34.4 0.1 1.5e-05 24.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR66148.1 - 1.5e-07 31.0 0.0 0.00021 20.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR66148.1 - 1e-06 28.9 0.3 3.5e-06 27.1 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMR66148.1 - 1.7e-06 28.5 0.0 6.5e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR66148.1 - 2.1e-06 26.7 0.2 0.0014 17.4 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 EMR66148.1 - 3.4e-06 26.6 0.2 0.005 16.2 0.4 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EMR66148.1 - 1.5e-05 24.3 0.2 2.2e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR66148.1 - 0.00087 18.6 0.0 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR66148.1 - 0.0012 17.8 0.2 0.026 13.4 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 EMR66148.1 - 0.0046 16.1 0.4 0.0066 15.6 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 EMR66148.1 - 0.0079 15.9 0.4 0.023 14.4 0.2 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 EMR66148.1 - 0.0079 15.6 0.4 0.013 14.9 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR66148.1 - 0.014 14.6 0.3 0.029 13.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EMR66148.1 - 0.033 14.2 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EMR66148.1 - 0.041 13.8 0.1 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR66148.1 - 0.089 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 EMR66149.1 - 1.3e-07 31.4 0.0 3.2e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR66149.1 - 3.4e-07 30.3 0.1 1e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR66149.1 - 0.19 11.0 0.9 0.41 9.9 0.6 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EMR66150.1 - 5.2e-25 88.0 0.0 7e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66150.1 - 1.3e-15 57.6 0.0 1.6e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR66150.1 - 8.6e-05 22.1 0.1 0.02 14.3 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR66150.1 - 0.0032 17.4 0.1 0.0067 16.4 0.1 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EMR66150.1 - 0.0045 16.6 0.1 0.0068 16.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR66150.1 - 0.018 14.9 0.2 0.052 13.4 0.2 1.8 1 1 0 1 1 1 0 NAD(P)H-binding DUF3533 PF12051.8 EMR66151.1 - 0.21 10.5 1.1 0.34 9.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) p450 PF00067.22 EMR66152.1 - 1.1e-64 218.9 0.0 1.4e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S7 PF00177.21 EMR66153.1 - 3.5e-15 56.0 0.0 1.1e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e HET PF06985.11 EMR66154.1 - 3.1e-07 30.8 0.0 5.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mito_fiss_reg PF05308.11 EMR66154.1 - 0.18 11.9 5.4 0.35 10.9 5.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EMR66154.1 - 0.2 11.1 7.4 0.39 10.2 7.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EMR66154.1 - 1.3 9.1 7.5 2.9 7.9 7.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MFS_1 PF07690.16 EMR66155.1 - 9.5e-17 60.9 30.4 1.3e-16 60.5 30.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.19 EMR66156.1 - 4.6e-15 55.0 0.0 2e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR66156.1 - 6.3e-11 42.1 0.0 2e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR66156.1 - 4e-09 36.1 0.3 1.2e-07 31.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EMR66156.1 - 1.4e-08 34.8 0.0 3.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR66156.1 - 1.3e-06 27.9 0.0 2.6e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR66156.1 - 2.3e-05 24.1 0.0 0.1 12.1 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR66156.1 - 3.9e-05 23.7 0.0 0.0078 16.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EMR66156.1 - 0.043 13.9 0.0 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Mqo PF06039.15 EMR66156.1 - 0.047 12.2 0.0 0.56 8.7 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Med15_fungi PF05397.12 EMR66157.1 - 0.0064 16.7 0.2 0.0064 16.7 0.2 2.9 4 0 0 4 4 4 1 Mediator complex subunit 15 Spore_III_AB PF09548.10 EMR66157.1 - 0.14 12.3 0.9 0.36 10.9 0.8 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Nitr_red_assoc PF09655.10 EMR66157.1 - 5.6 7.6 6.9 0.71 10.5 0.3 2.7 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF1996 PF09362.10 EMR66158.1 - 5.2e-64 216.4 0.4 7.7e-64 215.9 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltr_RsmB-F PF01189.17 EMR66159.1 - 5.6e-16 58.8 0.0 2.3e-09 37.2 0.0 2.8 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PB1 PF00564.24 EMR66159.1 - 0.16 11.9 0.3 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 PB1 domain MFS_1 PF07690.16 EMR66160.1 - 2.6e-38 131.9 42.9 2.6e-38 131.9 42.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3817 PF12823.7 EMR66160.1 - 3 8.7 8.2 0.46 11.3 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) Whi5 PF08528.11 EMR66162.1 - 1.7e-09 37.1 0.0 2.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Whi5 like CDC45 PF02724.14 EMR66162.1 - 0.25 9.6 2.9 0.29 9.4 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Gtr1_RagA PF04670.12 EMR66163.1 - 1.7e-67 227.1 0.1 2.1e-67 226.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EMR66163.1 - 0.00075 19.0 0.0 0.0019 17.7 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Neurexophilin PF06312.12 EMR66164.1 - 0.055 12.9 0.5 0.056 12.9 0.5 1.1 1 0 0 1 1 1 0 Neurexophilin Ank PF00023.30 EMR66165.1 - 3e-08 33.8 0.9 0.18 12.3 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EMR66165.1 - 2.1e-07 31.0 0.3 0.003 17.8 0.0 4.6 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR66165.1 - 2.2e-07 31.3 0.2 0.001 19.6 0.0 4.4 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR66165.1 - 8.1e-07 29.6 0.2 0.0061 17.1 0.0 3.5 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR66165.1 - 1.6e-06 28.0 0.1 0.24 12.1 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat FAD_binding_4 PF01565.23 EMR66166.1 - 8.1e-10 38.6 2.0 0.00038 20.2 0.8 2.8 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.12 EMR66166.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like DUF5122 PF17164.4 EMR66166.1 - 0.21 11.9 7.9 1.7 9.0 0.1 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller SET PF00856.28 EMR66168.1 - 2.5e-09 37.8 0.0 5.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.6 EMR66168.1 - 0.025 14.9 2.5 0.054 13.8 2.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat peroxidase PF00141.23 EMR66169.1 - 2.2e-22 79.9 0.1 3.8e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Peroxidase Zn_clus PF00172.18 EMR66170.1 - 0.0063 16.6 5.8 0.0063 16.6 5.8 4.9 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain YmgD PF16456.5 EMR66170.1 - 0.11 12.6 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 YmgD protein Rubredoxin_2 PF18073.1 EMR66170.1 - 6.5 6.6 8.8 3 7.7 0.2 4.0 3 0 0 3 3 3 0 Rubredoxin metal binding domain Hydantoinase_B PF02538.14 EMR66171.1 - 3.2e-171 570.3 0.5 6.3e-168 559.4 0.3 2.2 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMR66171.1 - 4.3e-93 311.7 0.0 8.6e-93 310.8 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMR66171.1 - 5.5e-57 192.3 0.0 1.7e-55 187.5 0.0 2.5 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 EMR66172.1 - 2.1e-27 96.0 35.0 1.4e-20 73.5 18.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CPP1-like PF11833.8 EMR66172.1 - 0.26 10.9 1.7 3.3 7.3 1.1 2.5 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like zf-RING_2 PF13639.6 EMR66173.1 - 5.5e-09 36.2 9.3 1.2e-08 35.1 9.3 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EMR66173.1 - 3.6e-06 27.1 9.3 1.6e-05 25.0 9.3 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EMR66173.1 - 0.00014 21.9 2.4 0.00039 20.4 2.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EMR66173.1 - 0.00019 21.7 8.0 0.00061 20.0 8.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EMR66173.1 - 0.00069 19.4 10.1 0.0014 18.4 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EMR66173.1 - 0.0011 18.8 3.5 0.0011 18.8 3.5 2.1 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 EMR66173.1 - 0.0015 18.6 8.1 0.0044 17.1 8.1 1.9 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 EMR66173.1 - 0.0034 17.0 5.4 0.0065 16.1 5.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EMR66173.1 - 0.012 15.4 6.2 0.026 14.4 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMR66173.1 - 0.013 15.3 8.7 0.028 14.3 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 EMR66173.1 - 0.13 12.2 6.3 0.28 11.1 6.3 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING-like PF08746.11 EMR66173.1 - 0.18 12.2 11.4 0.069 13.5 8.5 1.9 2 0 0 2 2 1 0 RING-like domain Prok-RING_4 PF14447.6 EMR66173.1 - 0.36 10.7 7.7 1.6 8.6 7.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 EMR66173.1 - 0.73 9.8 7.4 1.5 8.7 7.4 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 EMR66173.1 - 0.88 9.7 4.0 2.2 8.5 4.0 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 EMR66173.1 - 2.9 7.7 8.7 1.3e+02 2.5 8.7 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EMR66173.1 - 8.5 6.4 9.2 17 5.5 9.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RhoGAP PF00620.27 EMR66174.1 - 1.2e-18 67.3 0.0 3.6e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain Helo_like_N PF17111.5 EMR66174.1 - 0.00014 21.3 0.1 0.00024 20.5 0.1 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SBF PF01758.16 EMR66175.1 - 6.5e-51 172.8 11.1 6.5e-51 172.8 11.1 2.3 3 0 0 3 3 3 1 Sodium Bile acid symporter family Glyco_hydro_30C PF17189.4 EMR66176.1 - 1.3e-12 47.7 5.6 3.4e-12 46.4 5.6 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 EMR66176.1 - 1.8e-12 47.1 0.1 2.9e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EMR66176.1 - 8e-12 45.4 3.0 2.6e-09 37.2 0.0 2.6 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 EMR66176.1 - 1.8e-08 33.8 0.0 2.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Melibiase_C PF17801.1 EMR66176.1 - 0.019 15.0 0.1 0.09 12.9 0.1 2.2 1 1 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain PI-PLC-X PF00388.19 EMR66177.1 - 6.4e-46 155.5 0.0 1e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EMR66177.1 - 1.8e-38 131.4 0.0 3.3e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Fungal_trans PF04082.18 EMR66178.1 - 9.4e-24 83.9 0.0 4e-23 81.8 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1707 PF08044.11 EMR66178.1 - 0.004 17.2 1.2 0.0094 16.0 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) DUF3067 PF11267.8 EMR66178.1 - 0.19 12.3 0.1 2 9.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) Hist_deacetyl PF00850.19 EMR66179.1 - 4.7e-22 78.9 0.0 9.5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 EMR66179.1 - 0.00071 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 RTP801 C-terminal region Palm_thioest PF02089.15 EMR66181.1 - 1e-77 261.3 0.0 1.2e-77 261.1 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EMR66181.1 - 0.017 14.5 0.0 0.065 12.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 EMR66181.1 - 0.023 14.2 0.0 0.17 11.4 0.0 2.0 1 1 0 1 1 1 0 Lipase (class 2) DUF3425 PF11905.8 EMR66182.1 - 4.2e-15 55.8 0.0 2e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 EMR66182.1 - 0.24 11.5 4.5 0.43 10.7 4.5 1.4 1 0 0 1 1 1 0 Basic region leucine zipper ParA PF10609.9 EMR66183.1 - 4.1e-95 317.9 0.0 4.9e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EMR66183.1 - 1.4e-10 41.3 0.0 3.3e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMR66183.1 - 1.1e-05 25.4 0.0 6.4e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EMR66183.1 - 0.00051 19.3 0.7 0.0021 17.3 0.6 1.9 1 1 1 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 EMR66183.1 - 0.0016 17.8 0.0 0.0037 16.6 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 EMR66183.1 - 0.0056 16.3 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 EMR66183.1 - 0.009 15.8 0.1 2.4 8.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 EMR66183.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_NifH PF00142.18 EMR66183.1 - 0.015 14.8 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 EMR66183.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EMR66183.1 - 0.028 14.8 0.1 0.053 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 EMR66183.1 - 0.032 14.2 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EMR66183.1 - 0.038 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR66183.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EMR66183.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 EMR66183.1 - 0.16 12.5 0.1 0.33 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMR66183.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 EMR66183.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EMR66183.1 - 0.24 10.6 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SNF2_N PF00176.23 EMR66184.1 - 3.8e-47 160.7 0.1 1.2e-34 119.5 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR66184.1 - 5.2e-13 49.3 0.1 1.4e-12 48.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EMR66184.1 - 0.024 13.8 1.1 2.8 7.1 0.1 2.3 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 EMR66184.1 - 0.033 13.1 0.0 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 BCS1_N PF08740.11 EMR66185.1 - 2.4e-41 141.8 0.2 3.4e-41 141.3 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EMR66185.1 - 1.5e-17 64.3 0.0 2.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMR66185.1 - 0.00015 21.6 0.8 0.004 16.9 0.0 2.5 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EMR66185.1 - 0.00052 19.7 0.0 0.0042 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMR66185.1 - 0.0014 19.0 0.0 0.0068 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EMR66185.1 - 0.003 16.7 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EMR66185.1 - 0.0037 17.3 0.3 0.012 15.6 0.0 2.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EMR66185.1 - 0.0054 16.5 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EMR66185.1 - 0.0056 16.2 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 EMR66185.1 - 0.0078 16.7 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 EMR66185.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 EMR66185.1 - 0.015 14.1 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_33 PF13671.6 EMR66185.1 - 0.02 15.0 0.0 0.06 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EMR66185.1 - 0.024 14.7 0.3 0.063 13.4 0.0 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EMR66185.1 - 0.048 13.9 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EMR66185.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EMR66185.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Herpes_Helicase PF02689.14 EMR66185.1 - 0.097 10.6 0.0 1.9 6.3 0.0 2.0 2 0 0 2 2 2 0 Helicase RNA_helicase PF00910.22 EMR66185.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 EMR66185.1 - 0.13 12.7 0.0 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EMR66185.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF3632 PF12311.8 EMR66187.1 - 4e-08 33.9 0.3 5.9e-08 33.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Glyco_hydro_3_C PF01915.22 EMR66188.1 - 3.5e-40 138.2 0.0 6.8e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR66188.1 - 5.7e-36 124.5 0.0 9.9e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR66188.1 - 1.8e-22 79.2 0.1 3.3e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Myc_target_1 PF15179.6 EMR66189.1 - 5.7 6.8 8.1 1.6 8.6 0.8 2.5 2 0 0 2 2 2 0 Myc target protein 1 Cofilin_ADF PF00241.20 EMR66190.1 - 9.8e-20 70.6 0.0 1.1e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ank_3 PF13606.6 EMR66191.1 - 1.1e-12 46.9 0.7 2.1 9.2 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 EMR66191.1 - 5.4e-08 33.3 0.0 0.07 13.7 0.0 4.3 4 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR66191.1 - 3.5e-06 27.5 0.5 8.4 7.1 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 EMR66191.1 - 9.3e-06 25.9 4.9 6 7.5 0.0 6.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 EMR66191.1 - 0.00012 22.2 2.5 31 5.0 0.0 5.4 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Sacchrp_dh_NADP PF03435.18 EMR66191.1 - 0.039 14.2 0.4 1.1 9.6 0.0 2.8 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain F-box_4 PF15966.5 EMR66191.1 - 0.041 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 F-box Nod_GRP PF07806.11 EMR66191.1 - 0.14 12.0 3.2 0.23 11.3 3.2 1.3 1 0 0 1 1 1 0 Nodule-specific GRP repeat MFS_1 PF07690.16 EMR66193.1 - 1.4e-22 80.1 5.9 2.7e-14 52.9 2.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MIP PF00230.20 EMR66194.1 - 8e-49 166.4 14.4 1e-48 166.1 14.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein NACHT PF05729.12 EMR66196.1 - 2.4e-11 43.8 2.4 7.1e-11 42.3 2.4 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMR66196.1 - 1.9e-07 31.4 0.0 4.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR66196.1 - 3.5e-07 30.8 0.1 6.5e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 EMR66196.1 - 0.00097 18.5 0.1 0.32 10.2 0.0 2.2 2 0 0 2 2 2 2 KAP family P-loop domain ATPase_2 PF01637.18 EMR66196.1 - 0.0018 18.2 0.0 0.0048 16.8 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EMR66196.1 - 0.0021 18.6 0.0 0.018 15.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMR66196.1 - 0.0044 17.5 0.0 0.0087 16.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 EMR66196.1 - 0.005 17.3 0.0 0.028 14.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EMR66196.1 - 0.0058 16.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 EMR66196.1 - 0.011 14.9 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 EMR66196.1 - 0.013 15.2 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EMR66196.1 - 0.026 14.7 0.0 1 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EMR66196.1 - 0.049 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 EMR66196.1 - 0.058 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EMR66196.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EMR66196.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMR66196.1 - 0.12 12.4 0.0 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Parvo_NS1 PF01057.17 EMR66196.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EMR66196.1 - 0.14 11.4 0.0 0.38 10.0 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 EMR66196.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 EMR66196.1 - 0.23 10.4 0.0 0.39 9.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MTHFR PF02219.17 EMR66197.1 - 2.7e-110 368.2 0.0 5.6e-110 367.2 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Peptidase_M20 PF01546.28 EMR66198.1 - 8.8e-22 77.8 0.1 1.1e-20 74.3 0.1 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EMR66198.1 - 8.7e-07 28.8 0.0 1.9e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 EMR66198.1 - 5.5e-05 23.0 0.0 0.00017 21.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain APH PF01636.23 EMR66199.1 - 3.6e-11 43.4 0.3 4.8e-11 43.0 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMR66199.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cyclin_N PF00134.23 EMR66200.1 - 7.9e-09 35.3 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zn-ribbon_8 PF09723.10 EMR66200.1 - 0.0072 16.4 0.4 0.017 15.3 0.4 1.6 1 0 0 1 1 1 1 Zinc ribbon domain UQ_con PF00179.26 EMR66201.1 - 2.6e-24 85.5 0.1 4.2e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EMR66201.1 - 0.002 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 EMR66201.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 EMR66201.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 NIT PF08376.10 EMR66203.1 - 0.002 18.7 0.0 1.2 9.5 0.0 2.5 1 1 1 2 2 2 2 Nitrate and nitrite sensing Phage_TAC_7 PF10109.9 EMR66203.1 - 0.048 13.8 0.1 0.098 12.8 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 Ribosomal_L1 PF00687.21 EMR66205.1 - 3.4e-57 193.5 0.3 6.5e-57 192.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NUMOD3 PF07460.11 EMR66205.1 - 0.11 12.7 1.1 0.39 11.0 1.1 1.9 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) F-box-like PF12937.7 EMR66206.1 - 2.6e-05 24.0 0.2 8.3e-05 22.4 0.2 2.0 1 0 0 1 1 1 1 F-box-like Peptidase_M19 PF01244.21 EMR66207.1 - 8.2e-32 110.6 0.0 3.2e-25 88.9 0.0 2.1 1 1 1 2 2 2 2 Membrane dipeptidase (Peptidase family M19) PTS_2-RNA PF01885.16 EMR66208.1 - 4.6e-28 98.5 0.0 5.9e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF4939 PF16297.5 EMR66208.1 - 0.0072 16.2 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) AA_permease_2 PF13520.6 EMR66209.1 - 1e-60 205.8 32.8 1.3e-60 205.5 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR66209.1 - 5.7e-22 78.0 23.6 5.7e-22 78.0 23.6 2.0 2 0 0 2 2 2 2 Amino acid permease Helicase_C PF00271.31 EMR66210.1 - 6e-08 33.0 0.0 2.9e-07 30.8 0.0 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EMR66210.1 - 0.0015 17.8 0.0 0.0025 17.0 0.0 1.3 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PTS_2-RNA PF01885.16 EMR66210.1 - 0.0033 17.5 0.0 0.0049 16.9 0.0 1.3 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF2046 PF09755.9 EMR66210.1 - 0.053 12.8 0.1 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Ligase_CoA PF00549.19 EMR66210.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 CoA-ligase 2-Hacid_dh_C PF02826.19 EMR66211.1 - 2.9e-45 153.8 0.0 3.8e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR66211.1 - 5.6e-10 39.0 0.0 8.7e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMR66211.1 - 0.00046 20.4 0.0 0.00078 19.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMR66211.1 - 0.04 14.5 0.0 0.09 13.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-C2H2 PF00096.26 EMR66212.1 - 7.3e-10 38.7 19.3 0.00052 20.3 0.9 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMR66212.1 - 1.2e-08 35.0 17.4 5.3e-06 26.6 0.5 5.2 4 0 0 4 4 4 2 Zinc-finger double domain NACHT PF05729.12 EMR66212.1 - 2.3e-08 34.1 0.0 4.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain zf-C2H2_jaz PF12171.8 EMR66212.1 - 1.5e-05 25.1 5.5 0.012 15.9 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMR66212.1 - 0.00011 22.4 3.5 0.17 12.3 0.2 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EMR66212.1 - 0.00024 21.7 15.6 0.0094 16.7 1.0 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger NB-ARC PF00931.22 EMR66212.1 - 0.00078 18.7 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EMR66212.1 - 0.00078 19.7 0.4 0.018 15.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EMR66212.1 - 0.0058 17.0 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase zf-C2H2_6 PF13912.6 EMR66212.1 - 0.0065 16.4 0.6 0.0065 16.4 0.6 4.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2HE PF16278.5 EMR66212.1 - 0.008 16.6 1.9 4.7 7.7 0.2 3.2 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DUF2075 PF09848.9 EMR66212.1 - 0.0087 15.3 0.6 0.051 12.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EMR66212.1 - 0.0099 16.3 0.1 0.07 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EMR66212.1 - 0.05 13.6 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMR66212.1 - 0.055 13.4 0.2 0.2 11.5 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea HypA PF01155.19 EMR66212.1 - 0.06 13.4 0.4 0.15 12.1 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ResIII PF04851.15 EMR66212.1 - 0.096 12.7 1.3 0.37 10.8 1.2 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_32 PF13654.6 EMR66212.1 - 0.15 10.8 5.9 0.14 10.9 4.3 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMR66212.1 - 0.28 11.7 3.3 0.42 11.2 0.1 3.0 3 1 0 3 3 2 0 AAA domain LIM PF00412.22 EMR66212.1 - 0.37 11.0 3.4 9.8 6.5 3.4 2.9 1 1 0 1 1 1 0 LIM domain zf-C2H2_3rep PF18868.1 EMR66212.1 - 1.7 9.3 5.6 0.4 11.3 1.2 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats p450 PF00067.22 EMR66213.1 - 9.9e-37 126.8 0.0 3.6e-32 111.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Exo_endo_phos PF03372.23 EMR66215.1 - 2.5e-06 27.2 0.1 3.8e-06 26.6 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NmrA PF05368.13 EMR66216.1 - 1.6e-29 103.1 0.0 5.2e-29 101.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR66216.1 - 2.8e-10 40.4 0.1 3.9e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR66216.1 - 0.00033 20.2 0.1 0.00054 19.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EMR66216.1 - 0.0011 19.3 0.0 0.0027 18.0 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 EMR66216.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMR66216.1 - 0.15 11.1 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.22 EMR66217.1 - 6.2e-60 201.5 0.1 7.2e-60 201.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR66217.1 - 4.9e-20 71.9 0.0 7e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR66217.1 - 1.8e-07 30.8 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMR66217.1 - 2.8e-05 23.8 0.1 0.00013 21.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMR66217.1 - 0.00043 20.2 0.3 1 9.2 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMR66217.1 - 0.0026 17.8 0.0 0.0037 17.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EMR66217.1 - 0.0051 16.8 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EMR66217.1 - 0.0061 16.1 0.0 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B IstB_IS21 PF01695.17 EMR66217.1 - 0.22 11.3 1.1 2.4 7.9 0.2 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 EMR66217.1 - 0.23 11.2 1.4 3.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Iron_permease PF04120.12 EMR66218.1 - 0.46 10.2 0.1 0.46 10.2 0.1 2.2 3 0 0 3 3 3 0 Low affinity iron permease DUF3292 PF11696.8 EMR66218.1 - 0.75 8.1 4.7 1.2 7.4 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FAD_binding_3 PF01494.19 EMR66220.1 - 2.6e-13 49.9 1.5 2.3e-08 33.7 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EMR66220.1 - 2.5e-06 27.3 1.3 0.00011 21.9 0.2 2.5 1 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR66220.1 - 0.0003 20.1 0.5 0.092 12.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR66220.1 - 0.0011 19.5 0.1 0.0039 17.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR66220.1 - 0.029 14.6 0.1 0.064 13.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EMR66220.1 - 0.088 11.6 0.6 2.1 7.1 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EMR66220.1 - 0.13 11.5 0.2 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MoCF_biosynth PF00994.24 EMR66221.1 - 1.9e-16 60.0 0.0 3.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain FAS_N PF17828.1 EMR66221.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta NAD_binding_4 PF07993.12 EMR66222.1 - 1.7e-36 125.7 0.0 2.5e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EMR66222.1 - 4.6e-22 78.2 0.0 1.6e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EMR66222.1 - 1.2e-11 44.6 0.0 1.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR66222.1 - 6.1e-09 35.3 0.0 1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 EMR66222.1 - 0.00024 21.4 0.2 0.0022 18.3 0.2 2.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site Adenylsucc_synt PF00709.21 EMR66223.1 - 1.8e-149 498.3 0.0 3.2e-146 487.6 0.0 2.0 1 1 1 2 2 2 2 Adenylosuccinate synthetase adh_short PF00106.25 EMR66224.1 - 5.2e-07 29.3 0.0 3.6e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66224.1 - 0.0035 16.9 0.0 0.013 15.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HD_3 PF13023.6 EMR66225.1 - 1.4e-49 168.2 0.0 1.7e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EMR66225.1 - 2.8e-08 33.7 0.0 4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Esterase_phd PF10503.9 EMR66226.1 - 3.2e-23 82.4 1.8 4.4e-23 81.9 1.8 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMR66226.1 - 2.2e-06 27.3 0.8 4.6e-06 26.3 0.9 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EMR66226.1 - 0.016 14.1 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR66226.1 - 0.044 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Macoilin PF09726.9 EMR66227.1 - 0.04 12.5 6.8 0.025 13.1 5.3 1.3 1 1 0 1 1 1 0 Macoilin family F-box-like PF12937.7 EMR66228.1 - 0.00038 20.3 0.7 0.00073 19.4 0.7 1.5 1 0 0 1 1 1 1 F-box-like NMO PF03060.15 EMR66231.1 - 7.9e-29 101.1 3.8 1.4e-28 100.3 3.8 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 EMR66231.1 - 2.9e-10 39.7 6.7 4e-10 39.3 6.7 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMR66231.1 - 8.4e-05 21.7 0.3 8.4e-05 21.7 0.3 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMR66231.1 - 9.6e-05 21.7 0.1 9.6e-05 21.7 0.1 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase RCC1_2 PF13540.6 EMR66232.1 - 0.093 12.6 1.1 8.7 6.3 0.0 3.6 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat CTXphi_pIII-N1 PF16710.5 EMR66232.1 - 0.12 12.5 0.0 22 5.2 0.0 2.4 2 0 0 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII NAD_binding_2 PF03446.15 EMR66233.1 - 4.7e-22 78.8 0.3 5.4e-22 78.7 0.3 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase KAP_NTPase PF07693.14 EMR66233.1 - 0.02 14.2 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Shikimate_DH PF01488.20 EMR66233.1 - 0.021 14.9 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_71 PF03659.14 EMR66234.1 - 7.3e-121 403.5 0.3 8.3e-121 403.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF218 PF02698.17 EMR66235.1 - 2.1e-05 24.5 0.0 0.00014 21.9 0.0 2.3 3 0 0 3 3 3 1 DUF218 domain Mur_ligase_M PF08245.12 EMR66235.1 - 4.1e-05 23.7 0.0 7.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EMR66235.1 - 0.0071 16.6 0.0 0.04 14.2 0.0 2.3 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Sugar_tr PF00083.24 EMR66236.1 - 2.9e-85 286.8 23.6 3.4e-85 286.6 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66236.1 - 3.7e-29 101.8 35.7 1.2e-22 80.4 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR66236.1 - 0.00059 18.8 12.4 0.15 10.9 5.9 2.9 2 1 0 2 2 2 2 MFS_1 like family OATP PF03137.20 EMR66236.1 - 0.00078 17.9 2.6 0.00086 17.7 1.3 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 EMR66236.1 - 0.0026 16.8 8.6 0.0026 16.8 8.6 1.9 2 0 0 2 2 2 1 PUCC protein YtpI PF14007.6 EMR66236.1 - 3.1 8.0 6.4 1.2 9.4 1.7 2.7 2 0 0 2 2 2 0 YtpI-like protein PhyH PF05721.13 EMR66237.1 - 1.9e-20 74.0 0.0 2.2e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aldedh PF00171.22 EMR66238.1 - 2.5e-137 458.2 0.0 2.8e-137 458.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.25 EMR66239.1 - 1.1e-15 57.6 0.0 3.1e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMR66239.1 - 8.2e-08 32.4 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMR66239.1 - 7.7e-07 28.9 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FHA PF00498.26 EMR66240.1 - 8.6e-09 35.6 0.0 2.2e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain Peptidase_M20 PF01546.28 EMR66241.1 - 9.8e-24 84.2 0.1 1.3e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR66241.1 - 9.2e-08 32.0 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Glyco_hydro_71 PF03659.14 EMR66242.1 - 2e-127 425.1 3.3 2.3e-127 424.9 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Pkinase PF00069.25 EMR66243.1 - 3e-56 190.7 0.0 3.6e-46 157.7 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR66243.1 - 2e-34 119.0 0.0 8.7e-29 100.6 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR66243.1 - 4.9e-05 22.3 0.0 0.00013 20.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EMR66243.1 - 0.0054 16.1 0.0 0.056 12.7 0.1 2.1 1 1 1 2 2 2 1 Kinase-like HEAT PF02985.22 EMR66244.1 - 2.7e-09 36.5 4.9 0.21 11.9 0.0 5.2 5 0 0 5 5 5 4 HEAT repeat Pkinase PF00069.25 EMR66244.1 - 1e-08 34.9 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.6 EMR66244.1 - 6.2e-07 29.7 1.2 0.00017 21.9 0.4 3.3 2 1 2 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 EMR66244.1 - 1.8e-06 27.4 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 EMR66244.1 - 2.9e-05 24.2 0.0 0.00014 21.9 0.0 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EMR66244.1 - 7.6e-05 23.1 0.6 0.52 10.9 0.6 3.8 3 0 0 3 3 3 2 HEAT-like repeat Adaptin_N PF01602.20 EMR66244.1 - 0.27 9.8 0.1 4.5 5.7 0.0 2.0 1 1 1 2 2 2 0 Adaptin N terminal region DUF3824 PF12868.7 EMR66245.1 - 0.0023 18.6 5.3 0.0023 18.6 5.3 8.3 7 1 2 9 9 9 3 Domain of unknwon function (DUF3824) FAD_binding_3 PF01494.19 EMR66246.1 - 0.0022 17.3 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NmrA PF05368.13 EMR66247.1 - 1.1e-15 57.9 0.0 1.4e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family IFRD PF05004.13 EMR66248.1 - 7.1e-84 281.5 6.0 9.7e-84 281.1 6.0 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 EMR66248.1 - 0.022 15.1 2.3 7.4 7.0 0.2 2.7 1 1 2 3 3 3 0 HEAT repeats HEAT_EZ PF13513.6 EMR66248.1 - 0.023 15.2 0.4 12 6.5 0.1 3.3 3 0 0 3 3 3 0 HEAT-like repeat Arg_decarbox_C PF17944.1 EMR66248.1 - 0.059 13.9 0.2 0.059 13.9 0.2 2.9 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Ku_PK_bind PF08785.11 EMR66248.1 - 0.06 13.5 0.0 0.66 10.1 0.0 2.5 2 1 1 3 3 3 0 Ku C terminal domain like Nrap_D5 PF17406.2 EMR66248.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Citrate_synt PF00285.21 EMR66249.1 - 5.1e-97 325.2 0.0 6.2e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain adh_short PF00106.25 EMR66250.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66250.1 - 0.037 13.6 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase LigB PF02900.18 EMR66251.1 - 2.9e-33 115.1 0.0 3.9e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NmrA PF05368.13 EMR66252.1 - 1.6e-21 76.9 0.0 2.2e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR66252.1 - 5.1e-13 49.3 0.0 8.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMR66252.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EMR66252.1 - 0.13 12.9 0.1 0.26 11.9 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EMR66252.1 - 0.16 12.4 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Lipase_GDSL_2 PF13472.6 EMR66253.1 - 5e-13 49.8 0.4 6.8e-13 49.4 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR66253.1 - 1.1e-11 45.1 0.1 1.5e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EMR66253.1 - 0.035 14.2 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ADH_N PF08240.12 EMR66254.1 - 2.4e-14 53.1 0.3 5.3e-14 52.0 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR66254.1 - 1e-12 48.2 0.1 3.7e-07 30.2 0.1 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR66254.1 - 2e-05 25.7 0.0 4.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR66254.1 - 0.00013 21.5 0.2 0.18 11.3 0.0 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 EMR66254.1 - 0.0053 16.4 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 EMR66254.1 - 0.0066 17.1 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EMR66254.1 - 0.054 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 EMR66254.1 - 0.1 13.2 0.0 0.28 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EMR66255.1 - 5.4e-40 136.7 0.0 7.4e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR66255.1 - 9.2e-22 77.1 0.0 1.1e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EMR66255.1 - 0.00019 21.5 0.5 0.00039 20.5 0.1 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 EMR66255.1 - 0.0043 17.6 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 1 XdhC Rossmann domain Sugar_tr PF00083.24 EMR66258.1 - 1.5e-109 366.9 21.4 1.8e-109 366.7 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66258.1 - 1.2e-21 77.1 34.1 5.5e-16 58.4 4.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 EMR66260.1 - 1.1e-37 127.3 17.2 5.7e-10 39.6 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR66260.1 - 9.7e-13 48.2 0.8 0.006 16.8 0.0 4.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR66260.1 - 6.8e-08 31.8 1.4 0.32 9.9 0.0 4.9 3 2 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EMR66260.1 - 6.4e-05 22.0 0.1 6.4e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 EMR66260.1 - 0.0002 20.1 6.4 0.16 10.6 0.1 4.2 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Frtz PF11768.8 EMR66260.1 - 0.0015 17.0 0.0 0.0051 15.2 0.0 1.8 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 EMR66260.1 - 0.004 16.7 0.0 0.066 12.7 0.0 2.4 2 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 Hira PF07569.11 EMR66260.1 - 0.46 10.2 3.4 29 4.3 0.1 3.5 1 1 1 2 2 2 0 TUP1-like enhancer of split Glyco_hydro_61 PF03443.14 EMR66261.1 - 5e-65 219.3 0.1 9e-65 218.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 EMR66263.1 - 1.4e-07 30.8 0.0 2.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EMR66264.1 - 6.2e-19 68.1 0.3 1.7e-18 66.6 0.1 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR66264.1 - 0.033 14.3 1.5 0.063 13.4 1.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_33 PF10017.9 EMR66264.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent MFS_1 PF07690.16 EMR66265.1 - 9.2e-33 113.6 28.0 1.2e-32 113.2 28.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PNTB_4TM PF12769.7 EMR66265.1 - 0.21 12.1 6.3 0.13 12.7 1.2 2.6 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch GHMP_kinases_N PF00288.26 EMR66267.1 - 4e-10 39.8 0.0 8.3e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMR66267.1 - 0.00015 22.1 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal FAD_binding_4 PF01565.23 EMR66268.1 - 5.4e-24 84.5 0.3 1e-23 83.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain ACC_epsilon PF13822.6 EMR66268.1 - 0.77 10.5 6.8 12 6.7 0.0 3.0 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit FAD_binding_4 PF01565.23 EMR66269.1 - 8.8e-20 70.9 0.3 1.5e-19 70.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR66269.1 - 7e-05 22.8 0.2 0.00016 21.7 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Aldolase_II PF00596.21 EMR66270.1 - 2.4e-51 174.4 0.2 2.9e-51 174.0 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain BRCC36_C PF18110.1 EMR66270.1 - 0.16 12.1 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain PLAC8 PF04749.17 EMR66271.1 - 2e-21 76.8 14.2 2.6e-21 76.5 14.2 1.1 1 0 0 1 1 1 1 PLAC8 family ThiF PF00899.21 EMR66273.1 - 1.3e-17 64.0 0.0 6e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 ThiF family PufQ PF05398.11 EMR66273.1 - 0.045 13.9 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 PufQ cytochrome subunit E1_4HB PF16191.5 EMR66273.1 - 0.073 13.3 0.0 0.24 11.6 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Methyltransf_3 PF01596.17 EMR66274.1 - 1.3e-24 86.5 0.0 1.2e-11 44.3 0.0 2.0 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_24 PF13578.6 EMR66274.1 - 1.1e-08 36.1 0.0 1.8e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NST1 PF13945.6 EMR66276.1 - 0.037 14.2 8.8 0.024 14.8 7.3 1.4 1 1 0 1 1 1 0 Salt tolerance down-regulator VID27 PF08553.10 EMR66277.1 - 4.2e-193 641.2 0.0 5.6e-193 640.8 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EMR66277.1 - 4.7e-76 254.4 0.1 4.7e-76 254.4 0.1 2.5 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EMR66277.1 - 3.5e-45 152.8 1.9 1.5e-44 150.7 0.6 2.6 3 0 0 3 3 3 1 VID27 PH-like domain PTPRCAP PF15713.5 EMR66277.1 - 0.31 11.3 9.0 0.86 9.9 9.0 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 EMR66277.1 - 1.1 7.3 7.5 1.7 6.7 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAD_binding_3 PF01494.19 EMR66279.1 - 3.8e-10 39.5 0.0 4.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.23 EMR66280.1 - 2.9e-21 75.7 0.1 6.1e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR66280.1 - 0.01 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Fungal_trans_2 PF11951.8 EMR66281.1 - 9.3e-19 67.5 0.1 3.4e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain SNF2_N PF00176.23 EMR66282.1 - 7.6e-50 169.6 0.0 2e-49 168.2 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR66282.1 - 4.7e-12 46.2 0.0 1.3e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR66282.1 - 7.8e-07 29.2 0.0 1.9e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NMO PF03060.15 EMR66283.1 - 1.5e-23 83.7 0.2 2.7e-22 79.6 0.2 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EMR66283.1 - 1.9e-06 27.1 0.0 2.7e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain adh_short_C2 PF13561.6 EMR66284.1 - 2.4e-56 190.9 0.0 3.2e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR66284.1 - 1e-43 149.1 0.0 1.4e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR66284.1 - 2.6e-12 47.0 0.0 3.6e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR66284.1 - 0.0065 15.9 0.0 0.0085 15.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMR66284.1 - 0.007 15.5 0.1 0.047 12.8 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 EMR66284.1 - 0.032 14.7 0.1 0.061 13.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding PALP PF00291.25 EMR66284.1 - 0.038 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF1776 PF08643.10 EMR66284.1 - 0.04 13.3 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMR66284.1 - 0.041 13.3 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EMR66285.1 - 1.3e-46 158.2 0.0 1.8e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EMR66285.1 - 0.0024 17.9 0.0 0.0061 16.6 0.0 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh PF00389.30 EMR66285.1 - 0.0048 16.6 0.0 0.023 14.4 0.0 2.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 EMR66285.1 - 0.014 15.9 0.1 0.049 14.1 0.1 1.9 1 1 0 1 1 1 0 XdhC Rossmann domain ELFV_dehydrog PF00208.21 EMR66285.1 - 0.14 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MFS_1 PF07690.16 EMR66286.1 - 1.5e-23 83.3 16.0 5.1e-23 81.6 16.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily AMP-binding PF00501.28 EMR66287.1 - 1.3e-73 248.1 0.0 1.7e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EMR66287.1 - 2.1e-26 92.6 0.0 4.9e-21 74.9 0.0 2.9 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EMR66287.1 - 1.1e-09 38.4 0.0 2.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site HET PF06985.11 EMR66288.1 - 1.1e-07 32.3 0.0 1.7e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EMR66289.1 - 2.7e-06 27.9 0.0 0.011 16.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) F-box-like PF12937.7 EMR66289.1 - 2.4e-05 24.1 0.1 9.4e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like Ank_3 PF13606.6 EMR66289.1 - 6.5e-05 23.0 0.3 0.072 13.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EMR66289.1 - 0.00035 20.8 0.0 0.059 13.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF3104 PF11302.8 EMR66289.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) F-box_5 PF18511.1 EMR66289.1 - 0.058 13.0 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 F-box MFS_1 PF07690.16 EMR66291.1 - 3.6e-20 72.2 12.2 5.2e-17 61.8 6.5 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Halogen_Hydrol PF10112.9 EMR66291.1 - 0.049 13.6 1.4 0.095 12.7 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PdxA PF04166.12 EMR66292.1 - 7.9e-76 255.2 0.0 9.5e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Fungal_trans PF04082.18 EMR66293.1 - 8.9e-07 28.2 0.4 2.3e-06 26.8 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR66293.1 - 0.0004 20.4 9.9 0.00071 19.6 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EMR66294.1 - 4.2e-34 118.0 50.7 4.2e-34 118.0 50.7 3.3 1 1 1 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 EMR66294.1 - 3e-08 32.9 0.4 3e-08 32.9 0.4 2.6 3 0 0 3 3 3 1 LacY proton/sugar symporter CcmD PF04995.14 EMR66294.1 - 0.1 12.7 1.1 0.52 10.4 0.2 2.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) AAA PF00004.29 EMR66295.1 - 3.8e-32 111.5 0.2 2.3e-13 50.7 0.0 4.7 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EMR66295.1 - 5.7e-12 45.6 1.1 1.4e-09 38.0 0.4 3.3 3 0 0 3 3 3 1 AAA lid domain AAA_5 PF07728.14 EMR66295.1 - 2.1e-11 44.0 0.1 0.0088 16.0 0.0 4.1 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMR66295.1 - 1.4e-08 34.6 0.0 0.015 15.1 0.0 4.1 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR66295.1 - 1.8e-08 34.8 4.4 0.054 13.8 0.0 6.0 5 3 1 6 6 5 2 AAA domain AAA_33 PF13671.6 EMR66295.1 - 7.3e-08 32.7 0.1 0.042 14.0 0.0 4.1 4 1 0 4 4 3 2 AAA domain AAA_30 PF13604.6 EMR66295.1 - 4.3e-07 29.8 0.1 0.0025 17.6 0.0 3.4 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.6 EMR66295.1 - 4.4e-07 30.5 4.0 0.082 13.4 0.0 4.4 5 0 0 5 5 3 2 AAA domain AAA_16 PF13191.6 EMR66295.1 - 6.8e-07 29.8 0.2 0.022 15.2 0.0 4.3 4 0 0 4 4 3 2 AAA ATPase domain RNA_helicase PF00910.22 EMR66295.1 - 6.9e-06 26.4 0.1 0.21 12.0 0.0 3.8 4 0 0 4 4 3 2 RNA helicase Torsin PF06309.11 EMR66295.1 - 9.9e-06 25.7 0.0 1.1 9.4 0.0 3.9 3 0 0 3 3 3 2 Torsin AAA_19 PF13245.6 EMR66295.1 - 1.2e-05 25.6 1.1 0.3 11.4 0.2 3.8 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EMR66295.1 - 1.3e-05 24.6 0.0 0.26 10.6 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EMR66295.1 - 2e-05 24.4 0.0 0.093 12.4 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_24 PF13479.6 EMR66295.1 - 0.0002 21.1 0.9 0.77 9.5 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 EMR66295.1 - 0.00037 20.8 0.2 0.65 10.2 0.1 3.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EMR66295.1 - 0.0009 19.0 0.0 0.39 10.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EMR66295.1 - 0.001 19.5 2.0 0.49 10.8 0.1 4.2 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EMR66295.1 - 0.002 17.7 0.1 4.2 6.9 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_11 PF13086.6 EMR66295.1 - 0.0047 16.7 0.8 0.99 9.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 EMR66295.1 - 0.0052 16.5 0.0 14 5.3 0.0 4.2 5 0 0 5 5 5 0 Sigma-54 interaction domain AAA_2 PF07724.14 EMR66295.1 - 0.0061 16.7 0.0 25 4.9 0.0 3.9 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 EMR66295.1 - 0.0063 16.4 0.9 4.6 7.1 0.0 4.1 5 0 0 5 5 4 1 RsgA GTPase NTPase_1 PF03266.15 EMR66295.1 - 0.0092 15.9 0.4 0.48 10.3 0.1 2.8 3 0 0 3 3 3 1 NTPase SRP54 PF00448.22 EMR66295.1 - 0.01 15.5 0.1 5.9 6.5 0.0 3.2 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain MCM PF00493.23 EMR66295.1 - 0.02 14.0 0.0 1.9 7.5 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain TniB PF05621.11 EMR66295.1 - 0.021 14.2 0.0 3.9 6.8 0.0 3.9 3 1 1 4 4 4 0 Bacterial TniB protein tRNA_lig_kinase PF08303.11 EMR66295.1 - 0.033 14.3 0.0 8.4 6.5 0.0 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain CbiA PF01656.23 EMR66295.1 - 0.064 13.3 0.2 8.5 6.4 0.0 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 EMR66295.1 - 0.077 12.4 0.0 13 5.1 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NACHT PF05729.12 EMR66295.1 - 0.21 11.5 0.4 31 4.4 0.0 3.4 3 1 1 4 4 4 0 NACHT domain AAA_6 PF12774.7 EMR66295.1 - 0.21 10.5 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 EMR66295.1 - 0.26 11.8 4.2 2.6 8.6 0.0 4.0 4 1 0 4 4 3 0 ABC transporter DUF1282 PF06930.12 EMR66296.1 - 0.00086 19.1 0.2 0.0009 19.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) TMEMspv1-c74-12 PF11044.8 EMR66296.1 - 0.7 9.9 2.1 3.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein zf-B_box PF00643.24 EMR66297.1 - 0.19 11.9 6.3 5.5 7.2 1.2 2.9 2 0 0 2 2 2 0 B-box zinc finger zf-piccolo PF05715.13 EMR66297.1 - 1.1 9.4 7.9 0.19 11.9 1.7 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger DUF1712 PF08217.11 EMR66298.1 - 3.3e-11 42.4 0.0 3e-10 39.2 0.0 2.0 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) He_PIG PF05345.12 EMR66299.1 - 4.6e-12 45.9 14.2 0.002 18.3 0.3 5.3 5 0 0 5 5 5 4 Putative Ig domain ICL PF00463.21 EMR66300.1 - 7.9e-292 968.4 0.4 8.9e-292 968.2 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EMR66300.1 - 8.2e-12 45.1 0.4 1.6e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF3197 PF11432.8 EMR66300.1 - 0.01 15.7 0.4 6.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) DPBB_1 PF03330.18 EMR66301.1 - 0.00077 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase SOG2 PF10428.9 EMR66301.1 - 0.92 8.6 10.8 1 8.5 10.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PepSY_2 PF13670.6 EMR66301.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain RNA_Me_trans PF04252.13 EMR66302.1 - 1.3e-78 263.1 0.0 1.5e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase adh_short PF00106.25 EMR66303.1 - 2.6e-39 134.7 0.0 3.3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66303.1 - 2.2e-30 106.0 0.0 3.2e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66303.1 - 9e-09 35.5 0.1 1.8e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Yippee-Mis18 PF03226.14 EMR66304.1 - 4e-17 62.4 0.0 6.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF678 PF05077.12 EMR66304.1 - 0.32 11.1 3.1 5.3 7.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF678) DUF3984 PF13136.6 EMR66304.1 - 2.6 7.4 7.8 4.6 6.6 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Methyltransf_16 PF10294.9 EMR66305.1 - 1.5e-21 76.9 0.0 1.7e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Pro_isomerase PF00160.21 EMR66306.1 - 9e-47 159.3 0.1 1.4e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EMR66306.1 - 7.8e-05 22.5 10.8 0.00014 21.7 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR66306.1 - 0.00067 19.4 0.1 0.00067 19.4 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMR66306.1 - 0.0011 19.0 1.0 0.0024 17.9 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMR66306.1 - 0.023 15.0 5.6 0.11 12.9 2.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR66306.1 - 0.024 15.4 2.2 0.024 15.4 2.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMR66306.1 - 0.034 14.8 3.0 0.062 14.0 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EMR66306.1 - 0.082 13.1 7.7 0.13 12.4 5.8 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 EMR66307.1 - 7.9e-34 117.2 0.1 1.1e-33 116.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR66307.1 - 7.6e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain RasGAP PF00616.19 EMR66308.1 - 3.7e-10 39.9 0.8 0.0018 18.0 0.0 3.8 2 2 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EMR66308.1 - 0.0012 19.1 0.0 0.0038 17.5 0.0 1.8 1 1 0 1 1 1 1 C2 domain CaM-KIIN PF15170.6 EMR66308.1 - 0.14 12.4 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Calcium/calmodulin-dependent protein kinase II inhibitor Sugar_tr PF00083.24 EMR66309.1 - 9.9e-90 301.6 19.5 1.2e-89 301.3 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66309.1 - 3.2e-24 85.5 27.5 4.1e-17 62.1 7.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR66309.1 - 0.019 13.4 7.0 0.027 12.9 0.8 2.4 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Tyr_Deacylase PF02580.16 EMR66310.1 - 3.4e-52 176.8 0.3 4.2e-52 176.5 0.3 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Glyco_trans_2_3 PF13632.6 EMR66311.1 - 7.3e-48 163.1 2.8 7.3e-48 163.1 2.8 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMR66311.1 - 3e-05 23.9 0.0 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EMR66311.1 - 0.0035 16.8 0.0 0.0096 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EMR66311.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CheZ PF04344.13 EMR66311.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ zf-C2H2 PF00096.26 EMR66312.1 - 0.076 13.5 1.9 0.076 13.5 1.9 4.3 4 1 0 4 4 4 0 Zinc finger, C2H2 type TFIIIC_sub6 PF10419.9 EMR66313.1 - 4.1e-20 71.4 0.0 6.9e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Ino80_Iec3 PF14612.6 EMR66314.1 - 9.5e-52 177.0 8.1 5.8e-29 102.4 4.2 3.0 1 1 2 3 3 3 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling YabA PF06156.13 EMR66314.1 - 0.3 11.7 0.1 0.3 11.7 0.1 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Not3 PF04065.15 EMR66315.1 - 2.7e-91 305.1 25.3 2.7e-91 305.1 25.3 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EMR66315.1 - 8.3e-43 145.6 9.9 2.3e-42 144.2 9.9 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 EMR66315.1 - 0.012 15.5 3.2 0.027 14.3 3.2 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 EMR66315.1 - 0.012 15.9 3.7 0.012 15.9 3.7 2.9 3 0 0 3 3 3 0 Syntaxin-like protein ABC_tran_CTD PF16326.5 EMR66315.1 - 0.012 15.8 4.6 0.012 15.8 4.6 3.6 2 1 0 2 2 1 0 ABC transporter C-terminal domain Cep57_MT_bd PF06657.13 EMR66315.1 - 0.055 13.9 10.0 0.62 10.6 2.2 3.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 NIT PF08376.10 EMR66315.1 - 0.098 13.1 2.6 0.63 10.5 2.8 2.2 1 1 0 1 1 1 0 Nitrate and nitrite sensing DUF1192 PF06698.11 EMR66315.1 - 0.35 10.9 6.6 0.36 10.9 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MMPL PF03176.15 EMR66315.1 - 1.7 7.5 3.5 3.2 6.6 3.5 1.5 1 1 0 1 1 1 0 MMPL family Cob_adeno_trans PF01923.18 EMR66315.1 - 2.3 8.4 8.9 36 4.4 8.7 2.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase CorA PF01544.18 EMR66315.1 - 5.3 6.3 10.1 0.66 9.2 1.5 2.2 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4140 PF13600.6 EMR66315.1 - 6.1 7.4 8.5 10 6.6 1.5 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Trehalase PF01204.18 EMR66316.1 - 3.3e-193 643.2 0.0 4.1e-193 642.9 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EMR66316.1 - 2.3e-17 62.4 0.6 3.7e-17 61.7 0.6 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Glyco_hydro_127 PF07944.12 EMR66317.1 - 4.2e-101 339.0 1.7 1.8e-46 158.7 0.1 3.5 3 1 0 3 3 3 3 Beta-L-arabinofuranosidase, GH127 MRP-L20 PF12824.7 EMR66318.1 - 7.1e-54 182.4 9.0 8.6e-54 182.1 9.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 EMR66318.1 - 0.0021 18.1 1.4 0.0022 18.0 0.1 1.7 2 0 0 2 2 2 1 Neugrin PPR_2 PF13041.6 EMR66319.1 - 0.0014 18.8 0.0 0.042 14.1 0.0 3.1 3 0 0 3 3 3 1 PPR repeat family ODC_AZ PF02100.17 EMR66320.1 - 1.2e-43 147.7 0.3 1.7e-43 147.2 0.3 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme PP2C PF00481.21 EMR66321.1 - 3.1e-82 276.1 0.0 4.6e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C His_biosynth PF00977.21 EMR66322.1 - 8.3e-42 143.2 1.6 1.6e-40 139.0 1.6 2.8 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EMR66322.1 - 4.5e-21 75.5 0.0 6.6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EMR66322.1 - 1e-08 35.3 0.0 5.1e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EMR66322.1 - 0.00019 21.1 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EMR66322.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 EMR66322.1 - 0.034 13.9 0.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase C26 Dus PF01207.17 EMR66322.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Vps62 PF06101.11 EMR66323.1 - 3.8e-10 38.7 0.4 7.9e-10 37.6 0.4 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Cwf_Cwc_15 PF04889.12 EMR66323.1 - 5.1 6.8 6.1 0.68 9.6 0.5 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein LSM PF01423.22 EMR66324.1 - 3.5e-16 58.6 0.3 4.7e-16 58.2 0.3 1.2 1 0 0 1 1 1 1 LSM domain NAD_binding_10 PF13460.6 EMR66325.1 - 0.00079 19.4 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR66325.1 - 0.013 14.9 0.1 0.12 11.8 0.1 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EMR66325.1 - 0.036 14.2 0.0 0.082 13.0 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 EMR66325.1 - 0.086 11.9 0.1 0.14 11.2 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 EMR66325.1 - 0.15 11.2 0.0 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein WD40 PF00400.32 EMR66326.1 - 4.6e-29 100.1 24.1 1.7e-06 28.7 0.2 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR66326.1 - 1.6e-09 37.9 0.4 1 9.7 0.0 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMR66326.1 - 4.9e-05 23.3 0.6 0.41 10.5 0.1 3.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EMR66326.1 - 0.065 12.0 0.0 0.23 10.2 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like Ge1_WD40 PF16529.5 EMR66326.1 - 0.12 11.3 0.1 3.5 6.5 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MBOAT PF03062.19 EMR66327.1 - 2e-21 76.7 10.5 4.1e-21 75.7 10.3 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EMR66327.1 - 0.003 17.8 1.3 0.0086 16.3 1.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family HRXXH PF13933.6 EMR66328.1 - 4.6e-103 344.0 0.1 6.2e-103 343.6 0.1 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 EMR66328.1 - 1.8e-09 38.3 0.3 7.6e-08 33.0 0.1 2.7 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase ATP13 PF12921.7 EMR66329.1 - 2e-15 56.7 0.2 8.3e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ATPase expression Flu_M2 PF00599.17 EMR66330.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Glyco_hydro_28 PF00295.17 EMR66331.1 - 3e-46 158.0 13.2 4.2e-46 157.5 13.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EMR66331.1 - 0.17 11.7 17.1 0.07 13.0 13.9 2.2 1 1 1 2 2 2 0 Right handed beta helix region Kp4 PF09044.10 EMR66332.1 - 4e-38 130.3 4.8 4.7e-38 130.1 4.8 1.0 1 0 0 1 1 1 1 Kp4 DUF3464 PF11947.8 EMR66333.1 - 0.057 13.2 0.2 0.071 12.9 0.2 1.3 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 PIG-L PF02585.17 EMR66334.1 - 7.1e-26 91.4 0.0 1.2e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF863 PF05904.11 EMR66334.1 - 0.013 14.0 0.4 0.016 13.7 0.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) ANAPC1 PF12859.7 EMR66334.1 - 0.11 13.1 0.8 0.2 12.2 0.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Ribonuclease_T2 PF00445.18 EMR66335.1 - 6.3e-42 143.9 0.4 1.1e-41 143.1 0.4 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family HATPase_c PF02518.26 EMR66336.1 - 7.1e-24 84.5 0.0 1.8e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMR66336.1 - 3e-21 75.7 0.1 8.4e-21 74.2 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 EMR66336.1 - 1.1e-10 41.6 0.0 0.049 13.9 0.0 3.9 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 EMR66336.1 - 1.3e-08 35.0 0.0 0.086 13.1 0.0 4.7 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 EMR66336.1 - 1.7e-08 34.3 0.0 0.0017 18.3 0.0 3.7 4 0 0 4 4 4 2 PAS domain PAS_3 PF08447.12 EMR66336.1 - 3e-07 30.6 0.0 0.029 14.7 0.0 3.0 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 EMR66336.1 - 6.4e-07 29.3 0.2 1.3e-05 25.1 0.2 3.1 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EMR66336.1 - 1.1e-06 28.6 0.1 0.073 13.1 0.0 3.6 3 0 0 3 3 3 2 PAS fold HATPase_c_3 PF13589.6 EMR66336.1 - 0.0014 18.5 0.2 0.0059 16.4 0.2 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.7 EMR66337.1 - 4.3e-13 49.7 8.4 5.5e-07 30.1 1.4 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR66337.1 - 3.3e-08 33.2 7.8 0.038 14.5 0.2 5.6 5 1 1 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 EMR66337.1 - 3.1e-07 30.8 8.2 0.0002 21.8 1.3 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR66337.1 - 5e-07 29.9 6.4 0.0019 18.5 0.9 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EMR66337.1 - 1.6e-06 28.3 9.5 0.00021 21.6 1.5 4.6 5 0 0 5 5 5 2 Ankyrin repeat SnoaL_4 PF13577.6 EMR66338.1 - 3.6e-20 72.4 0.0 4.7e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF1831 PF08866.10 EMR66338.1 - 0.0061 17.0 0.0 0.0083 16.6 0.0 1.1 1 0 0 1 1 1 1 Putative amino acid metabolism SnoaL_2 PF12680.7 EMR66338.1 - 0.052 14.2 0.0 0.081 13.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain RraA-like PF03737.15 EMR66339.1 - 3.9e-05 23.9 0.1 6.9e-05 23.1 0.0 1.4 2 0 0 2 2 2 1 Aldolase/RraA MazE_antitoxin PF04014.18 EMR66339.1 - 0.061 13.3 0.1 1.5 8.9 0.0 2.1 1 1 1 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin Phage_holin_3_6 PF07332.11 EMR66340.1 - 1.4 9.0 5.8 2.6 8.1 5.8 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Dabb PF07876.12 EMR66341.1 - 2.3e-09 37.8 0.0 1.4e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Peptidase_S58 PF03576.14 EMR66341.1 - 0.06 12.9 0.1 0.067 12.7 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S58 DAO PF01266.24 EMR66342.1 - 1.9e-53 182.3 3.6 2.2e-53 182.1 3.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR66342.1 - 0.073 13.3 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HSP70 PF00012.20 EMR66343.1 - 1.8e-267 888.5 16.7 2e-267 888.3 16.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMR66343.1 - 4e-16 58.8 4.3 4e-14 52.2 1.2 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EMR66343.1 - 0.00043 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Big_3_4 PF13754.6 EMR66343.1 - 0.037 13.8 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function YlbD_coat PF14071.6 EMR66343.1 - 0.53 10.5 4.5 1.9 8.8 4.5 2.0 1 0 0 1 1 1 0 Putative coat protein DUF4363 PF14276.6 EMR66343.1 - 1.2 9.3 7.4 2.5 8.2 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) MFS_1 PF07690.16 EMR66344.1 - 5e-13 48.7 1.1 7.4e-13 48.1 1.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_7 PF13176.6 EMR66344.1 - 0.0095 15.9 0.6 0.15 12.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR66344.1 - 0.011 16.2 1.9 0.53 10.8 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMR66344.1 - 0.25 11.6 0.9 43 4.6 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR66344.1 - 5 8.0 11.8 0.37 11.5 4.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat V-ATPase_H_N PF03224.14 EMR66345.1 - 3.4e-76 256.6 0.0 4.1e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EMR66345.1 - 2.9e-34 117.7 0.0 1.5e-33 115.4 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 EMR66345.1 - 0.049 14.0 0.6 0.77 10.2 0.1 3.1 2 2 0 2 2 2 0 HEAT repeats HEAT PF02985.22 EMR66345.1 - 0.1 12.9 0.1 2.5 8.6 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat Cu-oxidase_2 PF07731.14 EMR66346.1 - 1.4e-17 63.7 9.2 1.4e-12 47.5 0.7 2.6 2 1 1 3 3 3 2 Multicopper oxidase Hfx_Cass5 PF18287.1 EMR66346.1 - 0.15 12.3 0.4 0.29 11.4 0.4 1.5 1 0 0 1 1 1 0 Integron Cassette Protein Hfx_Cass5 adh_short PF00106.25 EMR66347.1 - 2.8e-34 118.3 0.1 3.9e-34 117.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66347.1 - 3.5e-26 92.2 0.0 4.7e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66347.1 - 1.6e-05 24.9 1.6 3.5e-05 23.8 1.6 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMR66347.1 - 0.0092 15.4 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glyco_hydro_1 PF00232.18 EMR66348.1 - 8e-74 248.7 1.5 1.4e-71 241.3 1.5 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 KIP1 PF07765.12 EMR66349.1 - 0.12 12.5 0.6 0.23 11.6 0.6 1.4 1 0 0 1 1 1 0 KIP1-like protein Inositol_P PF00459.25 EMR66350.1 - 6.9e-51 173.4 1.4 1.6e-50 172.1 1.4 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family RCC1 PF00415.18 EMR66351.1 - 3.4e-61 203.7 6.6 1.4e-08 35.2 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMR66351.1 - 7.1e-37 124.5 22.4 2e-07 30.6 0.3 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 EMR66351.1 - 0.1 12.5 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain CN_hydrolase PF00795.22 EMR66353.1 - 8.7e-34 117.0 0.0 1.4e-33 116.4 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase GrpB PF04229.14 EMR66353.1 - 0.063 13.5 0.0 0.19 11.9 0.0 1.8 2 1 0 2 2 2 0 GrpB protein Band_7_C PF16200.5 EMR66353.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of band_7 Tht1 PF04163.12 EMR66354.1 - 1.5e-06 27.3 0.0 2.7e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein ICEA PF05315.11 EMR66354.1 - 0.01 15.3 0.1 0.021 14.3 0.0 1.4 1 1 0 1 1 1 0 ICEA Protein DUF3482 PF11981.8 EMR66354.1 - 0.051 13.0 0.5 0.072 12.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) NPV_P10 PF05531.12 EMR66354.1 - 0.099 13.1 0.2 0.2 12.1 0.2 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Rap1_C PF11626.8 EMR66355.1 - 1.4e-24 86.0 1.0 3.7e-24 84.6 0.5 2.0 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 EMR66355.1 - 3.5e-12 46.5 0.0 6.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 EMR66355.1 - 7.4e-09 35.7 0.0 3.3e-08 33.6 0.0 2.2 1 0 0 1 1 1 1 Rap1 Myb domain ARID PF01388.21 EMR66355.1 - 6.7e-06 26.7 0.1 1.7e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF768 PF05589.11 EMR66355.1 - 0.17 11.9 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF768) E1-E2_ATPase PF00122.20 EMR66356.1 - 5.5e-45 153.1 0.8 2.7e-44 150.8 0.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMR66356.1 - 9.7e-32 111.0 1.8 1.2e-26 94.4 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.26 EMR66356.1 - 8.1e-11 42.2 0.4 2.9e-10 40.4 0.1 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EMR66356.1 - 0.00042 20.1 1.9 0.0031 17.3 2.6 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 EMR66356.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat Phage_holin_3_7 PF05449.11 EMR66356.1 - 0.42 10.6 3.0 1.3 9.1 3.0 1.8 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 DUF2752 PF10825.8 EMR66356.1 - 0.96 9.6 3.7 0.89 9.7 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) Ribosomal_L6 PF00347.23 EMR66357.1 - 4.7e-18 65.6 0.0 2.4e-09 37.7 0.0 2.8 2 1 1 3 3 3 2 Ribosomal protein L6 zf-C3HC PF07967.13 EMR66358.1 - 1.4e-42 144.9 0.2 9.9e-37 125.9 0.1 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EMR66358.1 - 7.3e-28 96.6 0.1 7.3e-28 96.6 0.1 2.5 2 1 0 2 2 2 1 Rsm1-like BIR PF00653.21 EMR66358.1 - 0.00061 20.4 0.1 0.013 16.1 0.1 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain PAP_assoc PF03828.19 EMR66359.1 - 1.7e-14 53.8 0.0 3.6e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EMR66359.1 - 1e-07 32.1 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EMR66359.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF3915 PF13054.6 EMR66359.1 - 0.75 9.8 7.6 1.4 8.9 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DHHC PF01529.20 EMR66360.1 - 6.6e-33 113.7 0.7 6.6e-33 113.7 0.7 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase FAD_binding_1 PF00667.20 EMR66361.1 - 5.8e-63 212.4 0.0 1.4e-62 211.1 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain PFOR_II PF17147.4 EMR66361.1 - 2.6e-09 37.3 0.6 7e-09 35.9 0.6 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II NAD_binding_1 PF00175.21 EMR66361.1 - 1.9e-08 34.9 0.0 5.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 EMR66361.1 - 9.3e-07 29.1 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.20 EMR66361.1 - 0.01 15.7 0.3 0.026 14.4 0.3 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain TANGO2 PF05742.12 EMR66362.1 - 1e-67 228.9 0.0 1.2e-67 228.7 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 PDR_assoc PF08370.11 EMR66362.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Plant PDR ABC transporter associated APG12 PF04110.13 EMR66363.1 - 4.2e-24 84.8 0.0 5.9e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EMR66363.1 - 0.0029 17.8 0.0 0.0036 17.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Tfb2 PF03849.14 EMR66364.1 - 9.1e-26 90.7 0.4 1.6e-25 89.8 0.3 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EMR66364.1 - 1.8e-19 69.9 2.4 1.8e-19 69.9 2.4 1.5 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EMR66364.1 - 1e-05 25.7 0.1 1.7e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cytochrome_P460 PF16694.5 EMR66364.1 - 0.028 14.8 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome P460 p450 PF00067.22 EMR66365.1 - 3.4e-43 148.1 0.0 4.4e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.14 EMR66366.1 - 7.7e-34 117.3 6.6 9.5e-34 117.0 6.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pantoate_transf PF02548.15 EMR66367.1 - 1.1e-104 349.5 0.3 1.2e-104 349.3 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EMR66367.1 - 1.4e-08 34.5 0.1 2.5e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 EMR66367.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) dCMP_cyt_deam_1 PF00383.23 EMR66368.1 - 1.5e-08 34.5 0.0 3e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMR66368.1 - 2.1e-06 27.5 0.0 5.7e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EMR66368.1 - 0.008 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase Senescence PF06911.12 EMR66370.1 - 0.033 14.5 5.7 0.045 14.1 5.7 1.1 1 0 0 1 1 1 0 Senescence-associated protein VPS13_C PF16909.5 EMR66370.1 - 1.3 8.8 5.2 0.73 9.6 2.6 1.8 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal rve_3 PF13683.6 EMR66371.1 - 0.17 11.7 3.2 10 6.0 0.0 2.8 3 0 0 3 3 3 0 Integrase core domain FAM176 PF14851.6 EMR66371.1 - 1.4 8.5 5.9 2.1 8.0 5.1 1.8 1 1 0 1 1 1 0 FAM176 family SR-25 PF10500.9 EMR66371.1 - 5.5 6.5 34.1 0.11 12.1 17.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2231 PF09990.9 EMR66372.1 - 0.0029 18.0 0.1 0.0051 17.2 0.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) MARVEL PF01284.23 EMR66372.1 - 0.017 15.1 0.4 0.049 13.6 0.1 1.7 1 1 1 2 2 2 0 Membrane-associating domain Peptidase_M24 PF00557.24 EMR66373.1 - 6.3e-49 166.5 0.0 1.7e-48 165.1 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 EMR66373.1 - 2.1e-33 114.6 0.0 3.5e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain COesterase PF00135.28 EMR66374.1 - 1.9e-68 231.6 0.0 2.9e-45 155.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR66374.1 - 0.0022 17.9 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Dfp1_Him1_M PF08630.10 EMR66375.1 - 3.8e-44 149.9 0.0 3.8e-44 149.9 0.0 2.7 2 1 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EMR66375.1 - 4.7e-05 23.4 1.5 4.7e-05 23.4 1.5 1.9 2 0 0 2 2 2 1 DBF zinc finger TFIIA PF03153.13 EMR66375.1 - 0.32 10.9 29.0 0.27 11.2 20.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DGF-1_C PF11040.8 EMR66375.1 - 0.52 10.3 3.0 3 7.9 0.2 3.0 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Kringle PF00051.18 EMR66375.1 - 5.3 7.4 7.2 12 6.3 1.8 2.5 2 0 0 2 2 2 0 Kringle domain Sugar_tr PF00083.24 EMR66377.1 - 3.1e-47 161.5 32.5 5.9e-35 121.0 17.2 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EMR66377.1 - 5.6e-25 88.0 46.3 1.3e-17 63.8 18.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Rad51 PF08423.11 EMR66378.1 - 1.2e-125 417.9 0.0 1.5e-125 417.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EMR66378.1 - 4.7e-09 36.1 0.0 6.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EMR66378.1 - 2.6e-08 33.7 0.0 3.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EMR66378.1 - 3.2e-05 24.4 0.2 7.4e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 EMR66378.1 - 5.3e-05 22.7 0.0 0.00015 21.2 0.0 1.7 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.11 EMR66378.1 - 0.022 13.9 0.3 0.11 11.7 0.1 1.9 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.15 EMR66378.1 - 0.025 13.9 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 EMR66378.1 - 0.065 13.3 0.2 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain AAA_24 PF13479.6 EMR66378.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Aha1_N PF09229.11 EMR66379.1 - 1.4e-37 128.9 0.3 2.1e-37 128.4 0.3 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EMR66379.1 - 5.7e-21 75.0 0.6 1.3e-20 73.9 0.6 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein FSIP2 PF15783.5 EMR66379.1 - 0.056 11.4 0.2 0.076 10.9 0.2 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 Tannase PF07519.11 EMR66380.1 - 6.1e-58 196.9 0.0 8.2e-33 114.0 0.0 3.0 1 1 2 3 3 3 3 Tannase and feruloyl esterase Nuc_sug_transp PF04142.15 EMR66381.1 - 1.6e-100 336.3 4.1 2.1e-100 335.9 4.1 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EMR66381.1 - 1.5e-06 27.7 7.7 4.2e-06 26.2 7.7 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EMR66381.1 - 3.3e-06 27.3 26.7 0.00068 19.8 6.0 2.4 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EMR66381.1 - 0.017 14.3 0.1 0.017 14.3 0.1 2.5 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport TPT PF03151.16 EMR66381.1 - 0.05 12.9 12.5 0.16 11.3 5.2 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DMT_6 PF04342.12 EMR66381.1 - 1.1 9.5 7.4 6.9 6.9 0.2 2.9 2 1 1 3 3 3 0 Putative member of DMT superfamily (DUF486) cobW PF02492.19 EMR66382.1 - 3.3e-47 160.4 2.6 5e-34 117.4 0.2 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EMR66382.1 - 1.5e-19 69.7 0.4 3e-14 52.7 0.1 2.8 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 EMR66382.1 - 0.0045 16.0 1.2 1.4 7.8 0.1 2.5 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EMR66382.1 - 0.006 17.0 1.1 0.022 15.1 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMR66382.1 - 0.016 15.2 1.0 0.96 9.3 0.3 2.3 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 EMR66382.1 - 0.016 15.1 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 EMR66382.1 - 0.024 14.6 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EMR66382.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PBP1_TM PF14812.6 EMR66382.1 - 0.074 13.4 4.0 0.26 11.7 4.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_18 PF13238.6 EMR66382.1 - 0.13 12.8 1.9 0.42 11.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain CDC45 PF02724.14 EMR66382.1 - 0.14 10.4 1.4 0.23 9.7 1.4 1.3 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 EMR66382.1 - 4 7.4 7.4 0.73 9.8 3.0 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Pes-10 PF07149.11 EMR66382.1 - 8.5 5.3 7.4 19 4.2 7.4 1.5 1 0 0 1 1 1 0 Pes-10 NOA36 PF06524.12 EMR66382.1 - 8.8 5.6 12.2 21 4.3 12.2 1.5 1 0 0 1 1 1 0 NOA36 protein Lin-8 PF03353.15 EMR66383.1 - 0.008 15.8 5.5 0.0094 15.5 5.5 1.0 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF1754 PF08555.10 EMR66383.1 - 0.043 14.6 1.0 0.043 14.6 1.0 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Mpp10 PF04006.12 EMR66383.1 - 0.051 12.0 8.4 0.056 11.9 8.4 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 EMR66383.1 - 0.19 11.1 10.1 0.21 11.0 10.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EMR66383.1 - 2.7 6.2 8.8 3.2 5.9 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EMR66383.1 - 3 5.9 9.8 3.5 5.7 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 EMR66383.1 - 3.7 5.7 6.1 4.5 5.5 6.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DEAD PF00270.29 EMR66384.1 - 4.9e-28 98.1 0.0 8.9e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 EMR66384.1 - 1.6e-21 76.7 0.0 2.4e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain ResIII PF04851.15 EMR66384.1 - 4e-13 49.7 0.0 1.4e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMR66384.1 - 7.9e-09 35.8 0.0 3.4e-08 33.8 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EMR66384.1 - 0.00023 21.5 0.0 0.0022 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMR66384.1 - 0.0049 17.1 0.1 0.015 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EMR66384.1 - 0.016 15.0 0.0 0.082 12.8 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_30 PF13604.6 EMR66384.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EMR66384.1 - 0.047 13.2 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Adeno_IVa2 PF02456.15 EMR66384.1 - 0.08 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Abhydrolase_3 PF07859.13 EMR66387.1 - 1.7e-42 145.7 0.1 2.2e-42 145.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR66387.1 - 0.00026 20.0 0.1 0.00072 18.5 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 EMR66387.1 - 0.0092 15.6 0.0 0.018 14.6 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EMR66387.1 - 0.13 11.7 0.0 6.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Vps26 PF03643.15 EMR66388.1 - 4.5e-102 340.7 0.9 6.1e-102 340.3 0.9 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 MMR_HSR1 PF01926.23 EMR66388.1 - 8.3e-15 54.9 0.0 2.4e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMR66388.1 - 1.2e-06 28.2 0.0 1.5e-05 24.6 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMR66388.1 - 7.1e-05 22.8 0.0 0.00059 19.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase TniB PF05621.11 EMR66388.1 - 0.0064 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_28 PF13521.6 EMR66388.1 - 0.027 14.7 0.7 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EMR66388.1 - 0.07 12.7 0.0 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EMR66388.1 - 0.088 12.9 1.7 0.39 10.8 0.0 2.8 3 0 0 3 3 3 0 Dynamin family IL17R_D_N PF16742.5 EMR66388.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Roc PF08477.13 EMR66388.1 - 0.16 12.2 0.0 0.52 10.5 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MFS_1 PF07690.16 EMR66389.1 - 6.3e-14 51.7 31.0 5.4e-08 32.2 16.2 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR66389.1 - 3.2e-06 26.3 12.9 0.00019 20.4 3.6 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter p450 PF00067.22 EMR66390.1 - 5.6e-35 121.0 0.0 6.7e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol_A_exoN PF18305.1 EMR66390.1 - 0.17 12.2 1.1 13 6.2 0.0 2.7 3 0 0 3 3 3 0 3' to 5' exonuclease C-terminal domain Glyco_hydro_2_C PF02836.17 EMR66391.1 - 4.6e-101 337.9 0.0 9.5e-101 336.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EMR66391.1 - 1.1e-56 192.1 0.1 2.4e-56 191.1 0.1 1.6 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EMR66391.1 - 3.6e-37 127.9 0.3 1.6e-36 125.8 0.2 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EMR66391.1 - 3.5e-16 59.5 0.1 2.2e-15 56.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EMR66391.1 - 1.1e-11 45.4 1.4 8.6e-10 39.3 0.0 2.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 bZIP_2 PF07716.15 EMR66391.1 - 4.6 7.4 7.0 0.91 9.7 2.5 2.0 2 0 0 2 2 2 0 Basic region leucine zipper MFS_1 PF07690.16 EMR66392.1 - 3.3e-16 59.2 19.7 3.3e-16 59.2 19.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TPP_enzyme_N PF02776.18 EMR66393.1 - 6.3e-34 117.1 0.1 9.8e-34 116.4 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMR66393.1 - 3.7e-18 65.6 0.0 8.2e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EMR66393.1 - 1.9e-16 60.2 0.0 1.2e-14 54.3 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Amidase PF01425.21 EMR66394.1 - 9.5e-93 311.6 0.0 5.6e-92 309.0 0.0 1.9 1 1 0 1 1 1 1 Amidase FAD_binding_3 PF01494.19 EMR66395.1 - 4.5e-72 243.2 0.0 6.3e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMR66395.1 - 2.6e-30 105.6 0.0 5e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EMR66395.1 - 8.6e-06 25.2 0.0 0.00018 20.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR66395.1 - 9.3e-06 25.8 0.1 2.4e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR66395.1 - 7.3e-05 22.1 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EMR66395.1 - 0.00019 21.1 0.1 0.00037 20.2 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR66395.1 - 0.00082 18.5 0.3 0.0015 17.7 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR66395.1 - 0.0021 17.2 0.6 0.0039 16.3 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EMR66395.1 - 0.0034 16.1 0.0 0.0053 15.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein XdhC_C PF13478.6 EMR66395.1 - 0.0051 17.3 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain Pyr_redox_3 PF13738.6 EMR66395.1 - 0.0057 15.9 0.1 0.0092 15.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMR66395.1 - 0.011 15.1 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EMR66395.1 - 0.016 14.1 0.1 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 EMR66395.1 - 0.019 15.5 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR66395.1 - 0.024 14.0 0.5 0.047 13.0 0.4 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EMR66395.1 - 0.026 13.6 0.1 0.049 12.7 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 EMR66395.1 - 0.033 13.3 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 EMR66395.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMR66395.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMR66395.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_4 PF01565.23 EMR66396.1 - 2e-27 95.6 0.2 3.8e-27 94.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain PD40 PF07676.12 EMR66397.1 - 2e-10 40.3 1.8 0.00037 20.3 0.1 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ring_hydroxyl_A PF00848.19 EMR66398.1 - 1.8e-21 77.1 7.2 2.7e-10 40.6 1.1 2.5 2 1 1 3 3 3 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EMR66398.1 - 3.3e-13 49.4 0.0 6.5e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_3 PF01494.19 EMR66399.1 - 2.6e-18 66.4 0.1 1.2e-12 47.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EMR66399.1 - 2.8e-07 30.1 0.1 0.0021 17.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR66399.1 - 5.9e-07 28.7 3.9 0.0024 16.8 0.8 2.1 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EMR66399.1 - 7.3e-06 26.1 2.1 0.00059 20.0 2.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR66399.1 - 2.5e-05 23.5 0.7 7.5e-05 21.9 0.7 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EMR66399.1 - 3.1e-05 23.7 9.2 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR66399.1 - 0.0017 17.2 3.7 0.052 12.2 4.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EMR66399.1 - 0.0022 18.5 0.9 0.17 12.5 0.9 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR66399.1 - 0.0056 15.8 6.9 0.0056 15.8 6.9 2.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR66399.1 - 0.012 14.8 0.2 0.02 14.2 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR66399.1 - 0.035 13.3 0.3 0.13 11.5 0.3 1.7 2 0 0 2 2 2 0 Thi4 family Amino_oxidase PF01593.24 EMR66399.1 - 0.076 12.3 2.1 4.9 6.3 1.3 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EMR66399.1 - 0.11 11.9 6.8 0.15 11.3 6.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_16 PF10294.9 EMR66399.1 - 0.23 11.2 0.1 0.47 10.2 0.1 1.4 1 0 0 1 1 1 0 Lysine methyltransferase 3HCDH_N PF02737.18 EMR66399.1 - 0.31 10.9 2.2 0.52 10.2 2.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR66399.1 - 0.66 9.2 2.7 3.3 6.9 1.4 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EMR66399.1 - 1.1 8.3 7.7 0.68 9.0 6.1 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Oxidored_FMN PF00724.20 EMR66400.1 - 4.4e-78 262.9 0.0 1.1e-77 261.7 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 EMR66400.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Fungal_trans PF04082.18 EMR66402.1 - 1.8e-37 128.9 0.0 2.9e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.21 EMR66403.1 - 2.7e-17 62.8 0.0 5.4e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMR66403.1 - 7.3e-08 32.3 0.2 9.5e-06 25.4 0.0 2.5 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2334) adh_short_C2 PF13561.6 EMR66404.1 - 2.5e-50 171.2 0.3 2.9e-50 171.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR66404.1 - 3.1e-42 144.3 0.3 4e-42 143.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR66404.1 - 1.9e-08 34.5 1.1 4.4e-08 33.3 1.0 1.5 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.16 EMR66405.1 - 1.9e-34 119.2 29.5 2.8e-34 118.6 29.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EMR66405.1 - 0.0078 16.0 1.5 0.96 9.2 0.8 2.4 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DIOX_N PF14226.6 EMR66406.1 - 1e-31 110.1 0.0 1.5e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR66406.1 - 2.6e-22 79.2 0.0 7.4e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Aldedh PF00171.22 EMR66407.1 - 3.8e-118 394.9 0.0 4.4e-118 394.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMR66407.1 - 0.074 12.1 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DIOX_N PF14226.6 EMR66408.1 - 6.7e-18 65.6 0.0 1.4e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR66408.1 - 3.4e-13 49.9 0.0 5.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily THUMP PF02926.17 EMR66408.1 - 0.046 13.8 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 THUMP domain MFS_1 PF07690.16 EMR66409.1 - 1.5e-11 43.8 36.0 1.8e-06 27.1 23.4 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR66409.1 - 8.4e-08 31.5 20.6 0.0029 16.5 13.7 3.2 1 1 1 2 2 2 2 Sugar (and other) transporter Abhydrolase_1 PF00561.20 EMR66410.1 - 8.8e-44 150.1 0.0 3.8e-43 148.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EMR66410.1 - 0.0014 18.3 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase zf-RING_6 PF14835.6 EMR66410.1 - 0.19 11.6 0.8 0.45 10.4 0.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Aldo_ket_red PF00248.21 EMR66411.1 - 5.8e-49 166.9 0.0 7.8e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Med21 PF11221.8 EMR66412.1 - 3.7e-48 163.5 9.0 4.1e-48 163.3 9.0 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.6 EMR66412.1 - 0.0027 17.1 9.4 0.14 11.5 0.5 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Med9 PF07544.13 EMR66412.1 - 0.018 15.1 2.1 0.018 15.1 2.1 3.0 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HMMR_N PF15905.5 EMR66412.1 - 0.031 13.8 6.2 0.035 13.6 6.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 EMR66412.1 - 0.037 14.2 5.0 0.097 12.9 4.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spore_III_AB PF09548.10 EMR66412.1 - 0.041 14.0 2.4 0.053 13.6 2.4 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Cauli_AT PF03233.13 EMR66412.1 - 0.16 11.9 2.7 0.24 11.3 2.7 1.3 1 0 0 1 1 1 0 Aphid transmission protein DUF4226 PF10774.9 EMR66412.1 - 0.73 10.1 5.1 1 9.7 0.7 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4226) TMPIT PF07851.13 EMR66412.1 - 2.4 7.3 3.7 2 7.6 2.6 1.3 1 1 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 EMR66412.1 - 8.5 6.9 13.7 23 5.5 13.7 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region KIND PF16474.5 EMR66413.1 - 0.074 13.0 0.6 0.11 12.4 0.6 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain CENP-B_dimeris PF09026.10 EMR66413.1 - 0.64 10.4 4.4 1.6 9.2 3.8 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ank_2 PF12796.7 EMR66414.1 - 2.6e-68 226.6 20.2 4.2e-15 56.1 0.3 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR66414.1 - 3.2e-49 164.7 10.0 2.1e-09 37.8 0.7 8.4 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EMR66414.1 - 3.8e-47 156.8 12.0 1e-05 25.8 0.0 9.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 EMR66414.1 - 7.6e-39 127.3 3.3 0.0039 17.6 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EMR66414.1 - 2.8e-36 123.1 6.7 4.5e-08 33.2 0.5 6.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ligase_CoA PF00549.19 EMR66414.1 - 0.014 15.2 0.0 0.038 13.8 0.1 1.7 2 0 0 2 2 2 0 CoA-ligase HAD_2 PF13419.6 EMR66415.1 - 5.5e-11 42.9 0.0 7.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR66415.1 - 4.5e-10 40.2 0.0 1.9e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase 5_nucleotid PF05761.14 EMR66415.1 - 0.066 12.1 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase family CorA PF01544.18 EMR66416.1 - 1.1e-08 34.7 0.1 1.1e-08 34.7 0.1 2.8 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein SelK_SelG PF10961.8 EMR66416.1 - 0.023 15.3 0.1 0.023 15.3 0.1 2.5 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Remorin_N PF03766.13 EMR66416.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Remorin, N-terminal region eIF3_subunit PF08597.10 EMR66417.1 - 1.3 8.9 11.4 0.44 10.4 0.4 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit KH_1 PF00013.29 EMR66418.1 - 1.8e-33 114.2 1.0 1.6e-07 31.0 0.0 7.1 8 0 0 8 8 8 6 KH domain TGT PF01702.18 EMR66420.1 - 3.7e-103 345.3 0.0 2.7e-100 335.9 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase GFA PF04828.14 EMR66421.1 - 0.31 11.4 4.1 0.1 12.9 0.9 1.8 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Syndecan PF01034.20 EMR66422.1 - 0.028 14.3 1.2 0.049 13.5 1.2 1.3 1 0 0 1 1 1 0 Syndecan domain Sugar_tr PF00083.24 EMR66423.1 - 3.6e-94 316.2 28.0 4.2e-94 315.9 28.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66423.1 - 1.3e-18 67.1 30.0 1.3e-18 67.1 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_11 PF08241.12 EMR66424.1 - 7.9e-14 52.1 0.0 1.7e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR66424.1 - 8.7e-14 52.0 0.0 1.7e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR66424.1 - 2.7e-09 37.6 0.0 5.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR66424.1 - 1.2e-07 31.6 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR66424.1 - 5.8e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR66424.1 - 0.0025 17.2 0.0 0.0052 16.1 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family 2OG-FeII_Oxy_2 PF13532.6 EMR66425.1 - 6.3e-31 108.1 0.0 8.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EMR66425.1 - 6.7e-11 42.1 4.2 1.2e-10 41.3 4.2 1.4 1 0 0 1 1 1 1 GRF zinc finger NAD_binding_4 PF07993.12 EMR66427.1 - 9.4e-31 106.9 0.0 1.4e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EMR66427.1 - 1.9e-13 49.8 0.0 7.4e-12 44.6 0.0 2.2 1 1 1 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EMR66427.1 - 5.3e-11 42.5 0.0 9.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR66427.1 - 2.2e-05 24.7 0.0 7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 EMR66427.1 - 0.017 15.5 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EMR66427.1 - 0.019 14.9 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.17 EMR66427.1 - 0.019 14.1 0.0 0.57 9.2 0.0 2.7 2 1 0 2 2 2 0 RmlD substrate binding domain DUF2529 PF10740.9 EMR66428.1 - 0.027 14.1 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) HGAL PF15666.5 EMR66428.1 - 0.032 14.3 0.8 0.049 13.7 0.8 1.4 1 1 0 1 1 1 0 Germinal center-associated lymphoma DUF1743 PF08489.11 EMR66428.1 - 0.31 11.1 2.8 0.42 10.7 0.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1743) Isochorismatase PF00857.20 EMR66429.1 - 5.2e-36 124.4 0.0 5.9e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family NAD_binding_2 PF03446.15 EMR66430.1 - 2.5e-35 122.0 0.0 5.2e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMR66430.1 - 1.1e-13 51.5 1.1 1.6e-13 50.9 1.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EMR66430.1 - 0.00012 22.6 0.0 0.001 19.6 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EMR66430.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 EMR66431.1 - 1.8e-71 240.8 0.2 2.2e-71 240.5 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.19 EMR66432.1 - 1.6e-26 93.4 0.0 2.1e-15 56.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EMR66432.1 - 1.6e-08 34.2 0.1 5.1e-08 32.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR66432.1 - 7.1e-05 23.0 0.4 0.00031 20.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR66432.1 - 0.00013 21.6 0.2 0.00019 21.1 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR66432.1 - 0.00032 21.2 0.2 0.013 16.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR66432.1 - 0.0021 17.3 0.5 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EMR66432.1 - 0.033 13.8 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EMR66432.1 - 0.036 13.3 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EMR66432.1 - 0.054 12.6 0.1 0.088 11.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Myb_DNA-bind_3 PF12776.7 EMR66433.1 - 8.9e-22 77.9 0.4 2.3e-21 76.6 0.4 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RAP1 PF07218.11 EMR66433.1 - 1.4 7.2 3.6 1.7 6.9 3.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cutinase PF01083.22 EMR66435.1 - 2.1e-52 177.7 9.0 2.4e-52 177.5 9.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EMR66435.1 - 2e-06 27.5 0.1 2.7e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 EMR66435.1 - 0.018 15.6 0.1 0.022 15.4 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR66435.1 - 0.035 13.8 0.1 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 EMR66435.1 - 0.23 10.9 0.0 0.33 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Sec63 PF02889.16 EMR66436.1 - 1.5e-135 450.3 0.0 5.5e-81 271.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EMR66436.1 - 4.8e-49 166.5 0.5 2.7e-25 89.1 0.5 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EMR66436.1 - 5.1e-20 72.2 0.0 8e-10 39.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMR66436.1 - 3e-16 59.7 0.3 3.2e-06 27.5 0.0 4.5 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 EMR66436.1 - 6e-06 26.1 0.3 0.11 12.2 0.3 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EMR66436.1 - 8.1e-06 26.2 2.0 0.22 11.8 0.0 4.2 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.6 EMR66436.1 - 0.00021 21.6 0.8 0.038 14.3 0.7 2.6 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 EMR66436.1 - 0.0035 17.5 0.5 0.023 14.9 0.0 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain DUF3365 PF11845.8 EMR66436.1 - 0.0046 17.3 0.0 0.021 15.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3365) AAA PF00004.29 EMR66436.1 - 0.0095 16.4 4.1 15 6.0 0.0 4.8 4 2 1 5 5 4 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EMR66436.1 - 0.053 12.6 0.0 2.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EMR66436.1 - 0.092 12.5 0.3 10 5.8 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein TPR_MLP1_2 PF07926.12 EMR66438.1 - 8.9e-35 119.6 24.4 8.9e-35 119.6 24.4 18.9 10 5 9 19 19 19 3 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 EMR66438.1 - 0.008 16.2 6.1 0.008 16.2 6.1 21.5 13 8 7 20 20 20 5 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 EMR66438.1 - 0.011 15.7 0.9 0.011 15.7 0.9 17.9 8 5 8 17 17 17 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_trans PF04082.18 EMR66439.1 - 0.041 12.9 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain PRODH PF18327.1 EMR66439.1 - 0.15 12.3 0.8 0.71 10.1 0.0 2.4 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain SKG6 PF08693.10 EMR66440.1 - 0.00021 20.6 1.5 0.00044 19.6 1.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Squash PF00299.18 EMR66440.1 - 0.26 11.4 3.5 7.5 6.7 0.4 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor PTP_tm PF18861.1 EMR66440.1 - 0.66 9.9 3.1 0.52 10.3 1.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Fungal_lectin PF07938.12 EMR66443.1 - 0.00013 21.5 0.1 0.0085 15.5 0.0 2.1 2 0 0 2 2 2 2 Fungal fucose-specific lectin Ilar_coat PF01787.16 EMR66443.1 - 0.072 12.9 1.8 0.12 12.2 1.8 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein PQQ_3 PF13570.6 EMR66443.1 - 0.079 13.5 0.0 3.7 8.2 0.1 2.9 2 1 0 2 2 2 0 PQQ-like domain DUF2456 PF10445.9 EMR66444.1 - 1.1e-17 63.9 1.5 1.5e-17 63.4 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) MMR_HSR1 PF01926.23 EMR66445.1 - 2.6e-05 24.3 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF3712 PF12505.8 EMR66446.1 - 5e-11 42.9 0.2 1.6e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF3310 PF11753.8 EMR66446.1 - 0.2 11.9 0.0 0.53 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) L51_S25_CI-B8 PF05047.16 EMR66447.1 - 2.7e-22 78.4 0.0 5.2e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Arylsulfotran_2 PF14269.6 EMR66448.1 - 1.1e-46 159.6 0.0 1.6e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMR66448.1 - 6.9e-19 68.0 0.0 3.4e-18 65.7 0.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) adh_short PF00106.25 EMR66449.1 - 1.6e-25 89.7 0.0 2.7e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66449.1 - 1.4e-14 54.3 0.2 4.3e-14 52.6 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66449.1 - 6.9e-07 29.3 0.2 1.3e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR66449.1 - 0.0047 16.1 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMR66449.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMR66449.1 - 0.16 11.4 0.2 0.4 10.1 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TMEM135_C_rich PF15982.5 EMR66450.1 - 0.00011 22.8 0.0 0.0068 17.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 DUF3624 PF12292.8 EMR66450.1 - 0.037 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) PPI_Ypi1 PF07491.11 EMR66451.1 - 8.3e-24 83.2 4.9 6.3e-23 80.4 4.9 2.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor MFS_1 PF07690.16 EMR66452.1 - 0.00054 19.0 4.3 0.00054 19.0 4.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR66452.1 - 0.16 10.8 5.9 0.41 9.4 5.5 1.8 1 1 1 2 2 2 0 Sugar (and other) transporter Rbsn PF11464.8 EMR66453.1 - 0.0042 16.8 0.1 0.0081 15.9 0.1 1.4 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Peptidase_S8 PF00082.22 EMR66455.1 - 1.2e-11 44.5 0.7 1.2e-11 44.5 0.7 2.0 2 1 0 2 2 2 1 Subtilase family Ank_2 PF12796.7 EMR66455.1 - 0.00086 19.8 0.4 0.011 16.3 0.2 2.9 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) MT0933_antitox PF14013.6 EMR66455.1 - 0.041 14.2 0.7 3 8.2 0.0 2.6 2 0 0 2 2 2 0 MT0933-like antitoxin protein Ank_5 PF13857.6 EMR66455.1 - 0.078 13.3 0.1 16 6.0 0.0 3.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR66455.1 - 0.1 13.2 1.4 5.5 7.9 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat Glyco_hydro_127 PF07944.12 EMR66457.1 - 1.9e-132 442.4 2.9 2.1e-132 442.3 2.9 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF4986 PF16375.5 EMR66457.1 - 0.0074 16.9 0.0 0.02 15.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function Gloverin PF10793.9 EMR66457.1 - 0.07 13.0 0.1 0.44 10.4 0.0 2.3 1 1 0 1 1 1 0 Gloverin-like protein GMC_oxred_C PF05199.13 EMR66458.1 - 2.2e-32 112.6 0.1 5.3e-32 111.3 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR66458.1 - 4.6e-27 95.2 0.0 6.4e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase IMS PF00817.20 EMR66459.1 - 5.1e-33 114.2 0.0 1.9e-20 73.4 0.0 2.3 2 0 0 2 2 2 2 impB/mucB/samB family IMS_C PF11799.8 EMR66459.1 - 1.4e-10 41.9 0.0 3.7e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EMR66459.1 - 0.003 17.8 0.0 0.0082 16.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif GET2 PF08690.10 EMR66460.1 - 2e-45 155.8 0.0 3.5e-45 155.0 0.0 1.4 1 0 0 1 1 1 1 GET complex subunit GET2 WD40 PF00400.32 EMR66461.1 - 2.4e-09 37.6 17.8 0.016 16.0 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EMR66461.1 - 0.014 14.1 0.5 9.2 4.8 0.0 3.1 2 2 1 4 4 4 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EMR66461.1 - 0.028 13.3 0.1 0.34 9.8 0.1 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DUF627 PF04781.12 EMR66461.1 - 0.034 14.1 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) HLH PF00010.26 EMR66462.1 - 3.2e-08 33.4 0.0 3.2e-08 33.4 0.0 3.5 4 1 0 4 4 4 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 EMR66462.1 - 0.027 14.5 12.2 0.12 12.4 12.2 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Mcl1_mid PF12341.8 EMR66465.1 - 1.7e-79 267.2 0.0 2.9e-65 220.6 0.0 3.1 3 1 1 4 4 4 2 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EMR66465.1 - 4.6e-21 74.7 3.7 4.8e-08 33.5 0.0 7.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR66465.1 - 8.4e-18 64.5 0.0 8.5e-05 22.8 0.2 6.9 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EMR66465.1 - 3.1e-08 33.1 0.0 5.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.11 EMR66465.1 - 0.00027 20.9 0.1 0.0039 17.1 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.8 EMR66465.1 - 0.0027 17.7 1.2 0.0081 16.2 1.2 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.12 EMR66465.1 - 0.0034 15.5 0.0 0.011 13.7 0.0 1.7 2 0 0 2 2 2 1 IKI3 family MMS1_N PF10433.9 EMR66465.1 - 0.011 14.4 0.0 0.034 12.8 0.0 1.9 1 1 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ge1_WD40 PF16529.5 EMR66465.1 - 0.042 12.8 0.0 2.5 7.0 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EMR66465.1 - 0.056 11.8 0.0 1 7.6 0.0 2.5 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1631 PF07793.11 EMR66465.1 - 0.063 11.7 0.0 0.082 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) WD40_like PF17005.5 EMR66465.1 - 0.21 10.8 0.0 2.4 7.4 0.0 2.2 1 1 0 1 1 1 0 WD40-like domain dDENN PF03455.19 EMR66466.1 - 1e-13 51.0 0.6 1.6e-13 50.4 0.6 1.3 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 EMR66466.1 - 0.009 16.3 6.8 0.014 15.7 6.8 1.3 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 EMR66466.1 - 0.017 15.0 8.9 0.027 14.3 8.9 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 EMR66466.1 - 1.5 8.8 9.7 2.8 7.9 9.7 1.5 1 0 0 1 1 1 0 PHD-finger OrfB_Zn_ribbon PF07282.11 EMR66466.1 - 4.9 7.2 8.1 8.8 6.3 8.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF974 PF06159.13 EMR66467.1 - 8.3e-78 261.6 0.0 1.4e-77 260.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF974) RTBV_P12 PF06361.11 EMR66467.1 - 0.39 11.1 1.4 0.46 10.9 0.1 1.8 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Transp_cyt_pur PF02133.15 EMR66468.1 - 6.5e-89 298.7 39.3 8.5e-89 298.3 39.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ank_2 PF12796.7 EMR66469.1 - 1.3e-131 429.4 23.1 5.8e-17 62.0 0.0 14.9 4 3 11 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR66469.1 - 3.5e-108 352.7 7.0 3.5e-09 37.0 0.1 21.8 11 7 12 23 23 23 20 Ankyrin repeats (many copies) Ank PF00023.30 EMR66469.1 - 5.5e-87 282.7 41.0 9.3e-06 25.9 0.0 27.5 27 1 0 27 27 27 21 Ankyrin repeat Ank_5 PF13857.6 EMR66469.1 - 2e-80 263.8 29.7 1.1e-07 31.9 0.0 23.2 14 7 9 24 24 24 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR66469.1 - 8.8e-77 243.8 10.1 0.00052 20.3 0.0 28.5 29 0 0 29 29 29 15 Ankyrin repeat SPRY PF00622.28 EMR66469.1 - 3.8e-17 62.5 0.2 8.5e-17 61.4 0.2 1.6 1 0 0 1 1 1 1 SPRY domain GH-E PF14410.6 EMR66470.1 - 0.097 13.1 0.1 12 6.4 0.0 2.4 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Acetyltransf_1 PF00583.25 EMR66470.1 - 0.1 12.8 0.3 0.28 11.4 0.3 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Amidase PF01425.21 EMR66471.1 - 7.3e-88 295.5 0.0 8.7e-88 295.2 0.0 1.1 1 0 0 1 1 1 1 Amidase HECT PF00632.25 EMR66472.1 - 7.2e-74 249.0 0.0 1.9e-73 247.7 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF998 PF06197.13 EMR66473.1 - 0.004 16.8 8.2 0.46 10.1 4.6 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF998) LrgB PF04172.16 EMR66473.1 - 0.14 11.7 1.7 0.83 9.1 1.6 2.0 1 1 1 2 2 2 0 LrgB-like family FAM117 PF15388.6 EMR66473.1 - 0.21 11.0 2.6 0.32 10.4 2.6 1.2 1 0 0 1 1 1 0 Protein Family FAM117 Con-6 PF10346.9 EMR66474.1 - 4.6e-11 42.5 0.1 2e-10 40.5 0.4 1.9 2 0 0 2 2 2 1 Conidiation protein 6 TauD PF02668.16 EMR66476.1 - 5.2e-52 177.3 1.2 7.3e-52 176.8 1.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LupA PF18242.1 EMR66476.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain C2 PF00168.30 EMR66477.1 - 3.1e-28 98.1 0.0 2.3e-16 59.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain GFO_IDH_MocA PF01408.22 EMR66479.1 - 3.4e-16 60.2 0.0 6.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMR66479.1 - 0.001 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain G6PD_N PF00479.22 EMR66479.1 - 0.063 13.9 0.0 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain PseudoU_synth_2 PF00849.22 EMR66480.1 - 2.9e-15 56.7 0.0 5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.12 EMR66480.1 - 0.037 14.2 0.4 0.081 13.1 0.1 1.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Barwin PF00967.17 EMR66480.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Barwin family bZIP_1 PF00170.21 EMR66481.1 - 0.0028 17.7 12.6 0.069 13.3 12.7 2.2 1 1 0 1 1 1 1 bZIP transcription factor JAKMIP_CC3 PF16034.5 EMR66481.1 - 0.034 14.1 5.9 0.051 13.5 5.9 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain VSG_B PF13206.6 EMR66481.1 - 0.086 12.1 0.6 0.11 11.7 0.6 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain ASD2 PF08687.11 EMR66481.1 - 0.092 12.3 5.1 0.13 11.8 5.1 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF1003 PF06210.11 EMR66481.1 - 0.38 10.9 2.2 0.71 10.0 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) adh_short PF00106.25 EMR66482.1 - 1e-25 90.3 0.0 1.5e-17 63.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66482.1 - 8.9e-16 58.1 0.0 4e-12 46.2 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66482.1 - 2.3e-08 34.2 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR66482.1 - 0.011 15.1 0.1 0.029 13.8 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 EMR66482.1 - 0.016 15.7 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.21 EMR66482.1 - 0.075 12.5 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EMR66482.1 - 0.086 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Helicase_RecD PF05127.14 EMR66482.1 - 0.095 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Helicase Linker_histone PF00538.19 EMR66483.1 - 2.8e-26 91.7 0.1 2.8e-26 91.7 0.1 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 EMR66483.1 - 0.045 13.8 75.1 0.083 13.0 75.1 1.5 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DNA_pol_phi PF04931.13 EMR66484.1 - 6.8 4.7 8.4 13 3.7 8.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi Sulfotransfer_4 PF17784.1 EMR66486.1 - 1.4e-56 191.7 0.0 1.7e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR66486.1 - 0.0015 19.0 0.0 0.0088 16.4 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase family PsbN PF02468.15 EMR66486.1 - 0.53 10.2 1.5 1 9.3 1.5 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) SPX PF03105.19 EMR66488.1 - 0.019 14.9 6.5 0.02 14.8 6.5 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EMR66488.1 - 0.17 10.7 8.6 0.22 10.3 8.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 EMR66488.1 - 0.72 9.8 11.0 0.98 9.4 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Zip PF02535.22 EMR66488.1 - 0.73 9.0 6.8 0.87 8.7 6.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM76 PF16046.5 EMR66488.1 - 2.4 7.5 5.7 3 7.1 5.7 1.1 1 0 0 1 1 1 0 FAM76 protein RAP1 PF07218.11 EMR66488.1 - 4.9 5.3 17.0 6 5.0 17.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_hydro_43 PF04616.14 EMR66489.1 - 1.3e-13 50.9 3.7 2.1e-13 50.2 3.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.24 EMR66491.1 - 4.6e-64 217.0 17.3 5.3e-64 216.7 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66491.1 - 1.1e-20 73.9 34.7 5e-20 71.7 15.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF554 PF04474.12 EMR66491.1 - 0.005 16.3 9.1 0.0064 16.0 3.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF554) DUF5345 PF17280.2 EMR66491.1 - 0.54 10.3 6.1 0.23 11.4 0.2 3.1 4 0 0 4 4 4 0 Family of unknown function (DUF5345) HET PF06985.11 EMR66492.1 - 0.032 14.6 0.0 0.12 12.8 0.0 2.0 2 1 0 2 2 2 0 Heterokaryon incompatibility protein (HET) zf-RING_UBOX PF13445.6 EMR66492.1 - 0.093 12.8 0.4 0.21 11.6 0.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Neugrin PF06413.11 EMR66493.1 - 1.4e-08 35.0 0.3 1.4e-08 35.0 0.3 2.8 2 1 0 3 3 3 1 Neugrin SLATT_1 PF18181.1 EMR66493.1 - 0.052 13.5 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 CytochromB561_N PF09786.9 EMR66493.1 - 2 7.3 13.9 2.9 6.8 13.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal RNA_pol_A_bac PF01000.26 EMR66494.1 - 7.9e-31 106.7 0.0 1.3e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EMR66494.1 - 3.7e-16 58.3 0.0 9.8e-16 57.0 0.0 1.7 2 1 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_Phos_2 PF00328.22 EMR66494.1 - 0.02 14.2 0.0 0.82 8.9 0.0 2.1 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Proteasome PF00227.26 EMR66495.1 - 4.3e-53 179.6 0.0 4.4e-29 101.3 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EMR66495.1 - 1.2e-10 40.9 0.3 3.1e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Mito_carr PF00153.27 EMR66496.1 - 4.9e-50 167.4 0.6 1.1e-21 76.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Z1 PF10593.9 EMR66496.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Z1 domain Calcipressin PF04847.12 EMR66497.1 - 1.1e-53 181.8 0.0 1.4e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Calcipressin FMO-like PF00743.19 EMR66498.1 - 4e-17 61.8 0.0 3.8e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMR66498.1 - 2.1e-11 43.9 0.0 1.2e-09 38.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR66498.1 - 2.3e-11 43.5 0.0 9.9e-11 41.4 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR66498.1 - 4e-11 42.7 0.0 7.6e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fringe PF02434.16 EMR66498.1 - 1.7e-09 37.5 0.0 3.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DAO PF01266.24 EMR66498.1 - 1.4e-07 31.5 0.8 0.00013 21.7 0.1 3.6 2 2 2 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EMR66498.1 - 1.3e-06 27.8 0.1 0.00023 20.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EMR66498.1 - 3e-05 23.4 0.9 0.00011 21.6 0.0 2.2 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 EMR66498.1 - 0.00018 22.0 0.0 0.61 10.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR66498.1 - 0.0045 16.1 0.1 1.9 7.5 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein PAN_4 PF14295.6 EMR66498.1 - 0.007 16.3 1.5 0.023 14.6 1.5 1.9 1 0 0 1 1 1 1 PAN domain NAD_binding_9 PF13454.6 EMR66498.1 - 0.013 15.5 6.3 0.57 10.2 0.0 4.5 4 1 1 5 5 5 0 FAD-NAD(P)-binding ANAPC_CDC26 PF10471.9 EMR66498.1 - 0.042 14.7 2.9 0.66 10.8 2.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 PAN_1 PF00024.26 EMR66498.1 - 0.066 13.2 0.2 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 PAN domain NAD_binding_7 PF13241.6 EMR66498.1 - 0.21 12.1 0.0 0.74 10.3 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding PAN_3 PF08277.12 EMR66498.1 - 1.4 8.7 3.7 3.5 7.5 3.7 1.6 1 0 0 1 1 1 0 PAN-like domain Ribonuclease_3 PF00636.26 EMR66499.1 - 5.5e-35 120.2 0.0 3e-21 76.0 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EMR66499.1 - 3.4e-27 95.1 0.0 4.2e-15 56.1 0.0 3.5 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EMR66499.1 - 1.4e-19 70.1 0.1 3e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 EMR66499.1 - 1.2e-18 67.5 0.0 2.9e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMR66499.1 - 7e-18 65.0 0.0 1.9e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EMR66499.1 - 2.7e-14 53.5 0.0 8.5e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EMR66499.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Pec_lyase_C PF00544.19 EMR66500.1 - 2e-44 151.7 5.1 2.9e-44 151.2 5.1 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EMR66500.1 - 0.00034 20.5 8.7 0.0094 15.8 8.6 2.3 1 1 0 1 1 1 1 Right handed beta helix region GrpE PF01025.19 EMR66502.1 - 4.3e-46 156.6 11.5 1.6e-45 154.8 11.5 1.7 1 1 0 1 1 1 1 GrpE PLC-beta_C PF08703.10 EMR66502.1 - 0.12 12.3 9.2 0.33 10.9 9.2 1.7 1 1 0 1 1 1 0 PLC-beta C terminal tRNA-synt_2d PF01409.20 EMR66504.1 - 4.8e-48 163.8 0.1 1.7e-24 86.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EMR66504.1 - 2.5e-25 88.7 0.0 5.5e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain HATPase_c_2 PF13581.6 EMR66504.1 - 0.018 15.0 0.2 0.17 11.9 0.0 2.1 1 1 1 2 2 2 0 Histidine kinase-like ATPase domain DUF4235 PF14019.6 EMR66506.1 - 0.015 15.3 0.3 0.039 14.0 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) ADH_N PF08240.12 EMR66508.1 - 7.6e-07 29.0 0.0 2.1e-06 27.6 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR66508.1 - 0.00017 21.6 0.2 0.00027 20.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR66508.1 - 0.1 13.6 0.0 0.21 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Inhibitor_I68 PF10468.9 EMR66509.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 DUF1664 PF07889.12 EMR66509.1 - 6.3 6.9 9.1 1.9 8.5 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Mx_ML PF17536.2 EMR66510.1 - 0.098 12.4 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal 4F5 PF04419.14 EMR66511.1 - 1.3e-09 38.8 13.0 1.3e-09 38.8 13.0 2.3 1 1 1 2 2 2 1 4F5 protein family ResB PF05140.14 EMR66511.1 - 7.5 5.2 8.0 8.4 5.0 8.0 1.0 1 0 0 1 1 1 0 ResB-like family Presenilin PF01080.17 EMR66511.1 - 8.8 5.0 7.4 8.7 5.0 7.4 1.0 1 0 0 1 1 1 0 Presenilin GRAB PF10375.9 EMR66512.1 - 4.8e-09 35.8 0.1 9.7e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Spc7 PF08317.11 EMR66512.1 - 0.00031 19.8 33.0 0.00031 19.8 33.0 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EMR66512.1 - 0.0027 17.8 17.1 0.0027 17.8 17.1 5.2 3 1 2 5 5 5 2 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 EMR66512.1 - 0.0075 15.8 27.1 0.0075 15.8 27.1 3.1 1 1 2 3 3 3 2 Golgin subfamily A member 5 Filament PF00038.21 EMR66512.1 - 0.026 14.1 56.2 0.025 14.2 34.9 2.4 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 EMR66512.1 - 0.036 14.2 26.8 0.2 11.8 12.7 3.6 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EMR66512.1 - 0.045 13.8 24.5 0.69 10.0 5.1 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EMR66512.1 - 0.071 13.1 60.1 0.021 14.9 21.1 3.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FPP PF05911.11 EMR66512.1 - 0.11 10.7 49.5 0.0076 14.5 30.3 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Prominin PF05478.11 EMR66512.1 - 0.12 10.3 22.1 0.16 9.9 1.6 3.0 1 1 2 3 3 3 0 Prominin CALCOCO1 PF07888.11 EMR66512.1 - 0.57 9.0 58.3 52 2.5 57.2 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Baculo_PEP_C PF04513.12 EMR66512.1 - 0.6 10.2 15.3 3.3 7.7 3.6 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 EMR66512.1 - 0.62 9.4 63.6 0.047 13.0 15.9 3.7 2 1 1 4 4 3 0 Growth-arrest specific micro-tubule binding Nup54_57_C PF18570.1 EMR66512.1 - 1.1 8.9 10.3 2.1 8.0 0.1 4.6 4 0 0 4 4 4 0 NUP57/Nup54 C-terminal domain Occludin_ELL PF07303.13 EMR66512.1 - 1.2 9.9 29.0 1.2 10.0 0.9 4.3 1 1 3 4 4 4 0 Occludin homology domain NPV_P10 PF05531.12 EMR66512.1 - 1.6 9.3 15.6 2.2 8.8 1.4 4.3 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EMR66512.1 - 2.6 8.5 25.7 1.9 9.0 0.7 5.6 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 EMR66512.1 - 7.8 6.3 22.3 2.2 8.0 4.0 3.4 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF3584 PF12128.8 EMR66512.1 - 9.7 3.6 63.0 1.6 6.1 47.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Cu_bind_like PF02298.17 EMR66513.1 - 0.0065 16.5 0.0 0.021 14.8 0.0 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain RRM_1 PF00076.22 EMR66514.1 - 1.4e-13 50.4 0.0 3.8e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMR66514.1 - 0.02 14.9 0.1 0.048 13.7 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1731 PF08338.11 EMR66514.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Aa_trans PF01490.18 EMR66515.1 - 3.2e-61 207.3 24.5 9.3e-34 116.8 10.3 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein CHD5 PF04420.14 EMR66516.1 - 2.8e-62 209.3 2.6 3.5e-62 208.9 2.6 1.1 1 0 0 1 1 1 1 CHD5-like protein DUF3826 PF12875.7 EMR66516.1 - 0.022 14.9 0.1 0.03 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) Peptidase_S49_N PF08496.10 EMR66516.1 - 0.089 12.8 0.4 0.18 11.9 0.2 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TMEM223 PF14640.6 EMR66518.1 - 0.09 12.9 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 223 DUF4133 PF13571.6 EMR66518.1 - 0.28 11.5 1.8 0.59 10.5 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) Asp PF00026.23 EMR66519.1 - 3.1e-66 224.0 2.6 4.6e-66 223.4 2.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR66519.1 - 6.4e-14 52.6 5.1 4.8e-08 33.5 4.9 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EMR66519.1 - 0.00012 21.9 0.0 0.0016 18.2 0.0 2.1 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EMR66519.1 - 0.01 16.5 0.6 1.6 9.4 0.0 3.3 3 1 1 4 4 4 0 Aspartyl protease gag-asp_proteas PF13975.6 EMR66519.1 - 0.18 12.4 0.2 1.3 9.6 0.0 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease CFIA_Pcf11 PF11526.8 EMR66520.1 - 1.2e-05 25.7 0.8 8.5e-05 23.0 0.8 2.1 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf-C2H2_4 PF13894.6 EMR66520.1 - 0.0059 17.3 2.8 0.95 10.5 0.3 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-LITAF-like PF10601.9 EMR66520.1 - 0.013 15.7 0.4 3.1 8.1 0.2 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-C2HC_2 PF13913.6 EMR66520.1 - 0.021 14.7 2.1 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EMR66520.1 - 0.044 13.5 0.2 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf_UBZ PF18439.1 EMR66520.1 - 0.083 12.5 8.6 1.6 8.4 4.7 3.3 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 EMR66520.1 - 0.1 12.7 0.8 18 5.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_Tnp_IS91 PF14319.6 EMR66520.1 - 0.12 12.4 0.7 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain C1_1 PF00130.22 EMR66520.1 - 0.22 11.5 2.4 25 4.8 0.1 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-C2H2_12 PF18112.1 EMR66520.1 - 0.6 10.6 3.2 1.6 9.3 0.2 2.8 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_1 PF14446.6 EMR66520.1 - 2.3 8.2 6.8 25 4.9 0.1 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2 PF00096.26 EMR66520.1 - 2.6 8.7 7.6 8.9 7.0 0.8 2.8 3 0 0 3 3 2 0 Zinc finger, C2H2 type Bac_rhamnosid6H PF17389.2 EMR66521.1 - 2e-115 385.7 3.8 2.7e-115 385.3 3.8 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EMR66521.1 - 8.4e-62 208.0 0.1 1.6e-61 207.1 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 EMR66521.1 - 3.2e-30 104.1 0.0 8.3e-30 102.8 0.0 1.7 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 EMR66521.1 - 7.9e-25 86.5 0.1 2.5e-24 84.9 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain RuBisCo_chap_C PF18087.1 EMR66522.1 - 0.22 11.2 0.7 0.36 10.5 0.7 1.3 1 0 0 1 1 1 0 Rubisco Assembly chaperone C-terminal domain DUF2721 PF11026.8 EMR66522.1 - 2.9 7.8 8.8 0.21 11.5 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Glyoxalase_3 PF13468.6 EMR66523.1 - 8.4e-06 26.0 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Cyclin_N PF00134.23 EMR66524.1 - 6.2e-39 132.6 1.2 7.7e-39 132.3 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMR66524.1 - 1.9e-11 44.1 1.7 1.5e-10 41.2 1.7 2.2 1 1 0 1 1 1 1 Cyclin, C-terminal domain Caskin-Pro-rich PF16907.5 EMR66524.1 - 0.0047 17.4 0.1 0.01 16.4 0.1 1.5 1 0 0 1 1 1 1 Proline rich region of Caskin proteins TFIIA PF03153.13 EMR66525.1 - 4e-89 300.5 0.3 4.7e-89 300.3 0.3 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 EMR66525.1 - 0.12 12.1 3.0 0.19 11.4 3.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ADH_N PF08240.12 EMR66528.1 - 3.6e-13 49.3 1.4 5.4e-13 48.8 0.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR66528.1 - 2.8e-11 43.5 0.0 5.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMR66528.1 - 3.7e-05 23.1 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR66528.1 - 0.0059 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EMR66528.1 - 0.015 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EMR66528.1 - 0.065 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Aldo_ket_red PF00248.21 EMR66529.1 - 6.9e-54 183.0 0.0 7.8e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Kp4 PF09044.10 EMR66530.1 - 7.8e-05 22.7 0.1 0.00014 21.9 0.1 1.4 1 1 0 1 1 1 1 Kp4 Peptidase_S8 PF00082.22 EMR66531.1 - 1.7e-32 112.9 6.6 2.5e-32 112.3 6.6 1.2 1 0 0 1 1 1 1 Subtilase family Aminotran_3 PF00202.21 EMR66532.1 - 6.6e-80 268.7 0.0 8.1e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_M19 PF01244.21 EMR66533.1 - 1.8e-52 178.5 0.1 2.1e-52 178.3 0.1 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF3425 PF11905.8 EMR66534.1 - 5.2e-21 74.9 0.0 9.9e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) MFS_1 PF07690.16 EMR66536.1 - 8.8e-34 117.0 29.8 1.4e-33 116.3 27.3 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily IKI3 PF04762.12 EMR66537.1 - 2e-127 426.6 0.1 2.4e-127 426.3 0.1 1.0 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EMR66537.1 - 6.4e-08 32.8 1.2 0.49 10.7 0.0 5.5 3 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMR66537.1 - 4.5 8.3 7.8 2.1e+02 3.0 0.0 5.6 6 1 1 7 7 7 0 WD domain, G-beta repeat Hpt PF01627.23 EMR66538.1 - 3.9e-13 49.5 0.0 5.6e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Erp_C PF06780.11 EMR66538.1 - 0.027 14.5 0.5 0.032 14.3 0.5 1.2 1 0 0 1 1 1 0 Erp protein C-terminus DUF3984 PF13136.6 EMR66539.1 - 7.3e-34 117.6 12.5 8e-24 84.6 3.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3984) F-box-like PF12937.7 EMR66540.1 - 5.1e-12 45.5 0.0 2.6e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EMR66540.1 - 1.2e-06 28.7 16.2 0.0022 18.3 0.0 5.6 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.33 EMR66540.1 - 9.9e-05 22.1 0.0 0.00032 20.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 EMR66540.1 - 0.0036 17.2 16.1 0.91 9.7 0.0 7.7 9 0 0 9 9 9 2 Leucine Rich repeat Recep_L_domain PF01030.24 EMR66540.1 - 0.015 15.4 2.0 1.1 9.5 0.8 2.9 3 0 0 3 3 3 0 Receptor L domain LRR_8 PF13855.6 EMR66540.1 - 0.37 10.6 5.2 5 7.0 0.2 4.3 4 2 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 EMR66540.1 - 0.51 11.1 0.0 0.51 11.1 0.0 6.8 9 1 0 9 9 9 0 Leucine Rich Repeat adh_short PF00106.25 EMR66541.1 - 4.5e-39 133.9 0.8 5.9e-37 127.0 0.8 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66541.1 - 2.4e-38 132.0 2.8 5.8e-30 104.6 1.3 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66541.1 - 2.1e-12 47.3 1.4 5.8e-11 42.6 1.4 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR66541.1 - 0.00029 20.4 0.4 0.0026 17.2 0.4 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR66541.1 - 0.12 11.8 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF2632 PF10943.8 EMR66543.1 - 0.0056 16.3 7.4 0.0056 16.3 7.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2632) Carb_bind PF10645.9 EMR66544.1 - 0.06 13.6 0.4 6.2 7.1 0.1 3.1 3 0 0 3 3 3 0 Carbohydrate binding Auts2 PF15336.6 EMR66544.1 - 0.12 12.4 1.3 0.21 11.7 1.3 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein FAD_binding_4 PF01565.23 EMR66545.1 - 2.7e-21 75.8 1.1 4.9e-21 74.9 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR66545.1 - 1.5e-10 41.0 0.1 3.5e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like SprA-related PF12118.8 EMR66546.1 - 1.1 8.3 19.2 1.5 7.9 19.2 1.1 1 0 0 1 1 1 0 SprA-related family Presenilin PF01080.17 EMR66546.1 - 8.4 5.0 15.6 12 4.5 15.6 1.4 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.20 EMR66547.1 - 3.8e-226 752.0 8.3 4.2e-226 751.8 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMR66547.1 - 4.3e-15 55.3 0.1 3.7e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EMR66547.1 - 0.00062 19.5 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EMR66547.1 - 0.031 14.7 1.2 37 4.8 0.0 3.6 3 1 0 3 3 3 0 Cell division protein FtsA DUF1894 PF08979.11 EMR66547.1 - 0.14 12.6 0.1 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) DUF726 PF05277.12 EMR66549.1 - 2.7e-110 368.5 0.5 3.7e-110 368.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EMR66549.1 - 0.00024 21.3 0.0 0.00048 20.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EMR66549.1 - 0.015 15.9 1.8 0.015 15.9 1.8 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family PE-PPE PF08237.11 EMR66549.1 - 0.05 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain GCIP PF13324.6 EMR66549.1 - 0.053 13.1 0.2 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF3419 PF11899.8 EMR66550.1 - 4e-165 549.7 0.0 5.1e-165 549.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EMR66550.1 - 5.3e-14 52.4 0.0 5.1e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR66550.1 - 6e-08 33.3 0.0 1.2e-06 29.1 0.0 3.0 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR66550.1 - 7.8e-08 33.0 0.0 3.2e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR66550.1 - 1.3e-07 31.2 0.0 0.0011 18.4 0.0 2.5 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EMR66550.1 - 2e-06 27.7 0.0 6.9e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR66550.1 - 7.5e-06 26.5 0.0 0.00034 21.2 0.0 3.4 4 0 0 4 4 4 1 Methyltransferase domain PCMT PF01135.19 EMR66550.1 - 0.00091 19.0 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LRR_4 PF12799.7 EMR66552.1 - 1.8e-38 129.9 46.4 3e-09 37.0 1.4 6.3 1 1 8 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMR66552.1 - 2.4e-21 75.2 29.8 5.3e-05 22.9 1.6 5.6 4 2 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EMR66552.1 - 3.8e-13 49.3 12.4 1.8e-05 24.3 1.9 4.1 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EMR66552.1 - 0.0032 17.4 20.7 0.58 10.3 0.2 8.1 8 0 0 8 8 8 1 Leucine Rich repeat OAR PF03826.17 EMR66552.1 - 0.54 10.2 1.8 1 9.3 1.8 1.5 1 0 0 1 1 1 0 OAR domain LRR_1 PF00560.33 EMR66552.1 - 3.2 8.7 23.5 39 5.3 0.1 7.6 7 1 0 7 7 7 0 Leucine Rich Repeat UDG PF03167.19 EMR66553.1 - 1.9e-20 73.4 0.0 2.8e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PQ-loop PF04193.14 EMR66555.1 - 3.9e-18 65.0 1.4 1.1e-07 31.6 0.0 3.2 2 1 0 2 2 2 2 PQ loop repeat DUF3927 PF13064.6 EMR66555.1 - 0.098 12.7 3.5 3.5 7.7 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3927) Piwi PF02171.17 EMR66556.1 - 1.5e-70 237.9 0.0 1.2e-69 234.9 0.0 2.0 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EMR66556.1 - 1.3e-18 67.9 0.0 2.4e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EMR66556.1 - 1.1e-14 53.8 0.2 2.4e-14 52.7 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EMR66556.1 - 2e-11 43.9 0.0 4.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 EMR66556.1 - 4.2e-06 27.0 0.1 1.4e-05 25.3 0.1 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain Aldo_ket_red PF00248.21 EMR66558.1 - 8.3e-39 133.5 0.0 1.3e-38 132.9 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Nop14 PF04147.12 EMR66559.1 - 7 4.7 13.9 10 4.2 13.9 1.2 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.18 EMR66561.1 - 2.8e-09 36.4 0.2 3.7e-09 36.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2c PF01411.19 EMR66562.1 - 4e-08 32.2 0.2 5.8e-08 31.7 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EMR66562.1 - 1.7e-05 24.8 0.4 3.3e-05 23.9 0.4 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF1857 PF08982.11 EMR66563.1 - 1.1e-61 207.0 0.0 1.2e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DUF4188 PF13826.6 EMR66565.1 - 4.5e-29 101.2 0.3 6.8e-29 100.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EMR66565.1 - 4.7e-05 22.9 0.1 6.4e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase Dabb PF07876.12 EMR66565.1 - 0.18 12.4 0.0 0.31 11.7 0.0 1.3 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain LMBR1 PF04791.16 EMR66566.1 - 3.9e-20 72.3 13.6 2.9e-18 66.1 10.8 2.5 2 1 0 2 2 2 1 LMBR1-like membrane protein GRP PF07172.11 EMR66566.1 - 0.074 13.7 0.3 0.074 13.7 0.3 3.6 5 0 0 5 5 5 0 Glycine rich protein family ETRAMP PF09716.10 EMR66566.1 - 5.3 7.2 0.0 5.3 7.2 0.0 3.6 7 0 0 7 7 7 0 Malarial early transcribed membrane protein (ETRAMP) UDPGP PF01704.18 EMR66567.1 - 1.1e-45 156.0 0.0 4e-44 150.9 0.0 2.0 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EMR66567.1 - 0.0031 17.9 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MFS_1 PF07690.16 EMR66568.1 - 1.7e-41 142.4 33.2 1.6e-39 135.9 9.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR66568.1 - 1.8e-11 43.6 0.5 1.8e-11 43.6 0.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 EMR66568.1 - 0.00037 19.6 6.5 0.0006 18.9 0.1 2.2 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_1_like PF12832.7 EMR66568.1 - 1.1 8.0 17.3 0.013 14.4 3.8 3.0 2 2 0 2 2 2 0 MFS_1 like family Fungal_trans PF04082.18 EMR66569.1 - 0.00027 20.1 0.0 0.0013 17.8 0.0 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain Staufen_C PF16482.5 EMR66569.1 - 0.096 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Staufen C-terminal domain UbiA PF01040.18 EMR66570.1 - 9.5e-15 54.6 0.0 1.3e-07 31.2 0.0 2.3 1 1 1 2 2 2 2 UbiA prenyltransferase family CENP-B_dimeris PF09026.10 EMR66571.1 - 0.065 13.6 5.2 0.12 12.8 5.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EMR66571.1 - 0.46 10.1 3.8 0.74 9.5 3.8 1.2 1 0 0 1 1 1 0 FAM176 family PhoLip_ATPase_C PF16212.5 EMR66572.1 - 7.5e-66 222.4 14.2 7.5e-66 222.4 14.2 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMR66572.1 - 6.7e-23 80.2 2.9 2.5e-22 78.3 0.2 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EMR66572.1 - 8.3e-12 45.8 0.1 2.1e-05 24.9 0.0 3.4 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EMR66572.1 - 3.9e-10 39.5 0.0 1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EMR66572.1 - 1.2e-08 34.9 0.0 1.4e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMR66572.1 - 0.02 14.6 0.0 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Peptidase_U4 PF03419.13 EMR66572.1 - 1.9 7.7 5.9 5.2 6.3 5.9 1.7 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Caleosin PF05042.13 EMR66573.1 - 1.6e-79 265.8 0.0 1.9e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein TPR_9 PF13371.6 EMR66574.1 - 0.0015 18.6 0.2 0.0072 16.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Peptidase_M20 PF01546.28 EMR66575.1 - 1.1e-06 28.5 0.4 1.7e-06 27.9 0.4 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR66575.1 - 6.8e-06 26.0 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain GMC_oxred_N PF00732.19 EMR66576.1 - 5.2e-62 209.9 0.0 6.8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR66576.1 - 7.1e-28 97.9 0.0 2.7e-27 96.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR66576.1 - 4.5e-09 35.9 0.0 0.00012 21.3 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EMR66576.1 - 2.8e-06 26.6 0.7 1.5e-05 24.3 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EMR66576.1 - 7.2e-06 25.4 0.0 0.00026 20.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR66576.1 - 8.5e-05 22.3 0.0 0.0034 17.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR66576.1 - 0.00026 21.1 0.2 0.00079 19.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR66576.1 - 0.00044 19.6 0.2 0.14 11.4 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR66576.1 - 0.0015 17.8 0.2 0.0025 17.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EMR66576.1 - 0.0039 16.0 0.1 0.0074 15.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.18 EMR66576.1 - 0.016 15.5 0.9 0.055 13.7 0.1 2.3 2 1 1 3 3 3 0 TrkA-N domain Trp_halogenase PF04820.14 EMR66576.1 - 0.029 13.2 0.3 0.041 12.7 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 EMR66576.1 - 0.041 14.4 0.4 0.18 12.4 0.1 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR66576.1 - 0.043 13.1 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EMR66576.1 - 0.075 13.0 0.3 0.39 10.7 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding HSCB_C PF07743.13 EMR66577.1 - 1.7e-20 73.3 3.2 1.7e-20 73.3 3.2 2.1 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EMR66577.1 - 0.00038 20.5 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.13 EMR66578.1 - 0.34 10.8 5.7 0.37 10.7 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 EMR66579.1 - 2.9e-42 145.0 0.0 3.4e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EMR66580.1 - 7.1e-27 93.8 1.2 1.1e-26 93.2 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR66580.1 - 0.13 12.4 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 Berberine and berberine like Sugar_tr PF00083.24 EMR66581.1 - 7.1e-89 298.7 18.5 1.2e-88 297.9 18.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66581.1 - 5.4e-31 107.8 23.1 2.6e-23 82.5 5.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR66581.1 - 0.0093 14.6 0.3 0.0093 14.6 0.3 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 EMR66581.1 - 0.73 8.0 13.5 0.1 10.8 0.4 3.4 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family BCHF PF07284.11 EMR66582.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) MFS_2 PF13347.6 EMR66583.1 - 5.5e-11 41.7 8.6 2.8e-10 39.4 5.8 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 EMR66583.1 - 0.0003 19.8 0.5 0.0015 17.5 0.5 1.9 2 1 0 2 2 2 1 MFS_1 like family Acatn PF13000.7 EMR66583.1 - 0.0063 15.1 0.1 0.011 14.3 0.1 1.3 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 DUF3278 PF11683.8 EMR66583.1 - 0.043 13.9 0.0 14 5.8 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF3040 PF11239.8 EMR66583.1 - 0.1 12.9 0.7 2.1 8.7 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) HisG PF01634.18 EMR66584.1 - 7.6e-55 185.2 0.0 1.2e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EMR66584.1 - 6.6e-26 90.3 0.3 1.1e-25 89.5 0.3 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EMR66584.1 - 0.035 14.1 0.0 3.1 7.7 0.0 2.5 2 1 0 2 2 2 0 NMT1/THI5 like DUF1697 PF08002.11 EMR66584.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) MBOAT_2 PF13813.6 EMR66585.1 - 2.5e-16 59.7 5.5 9.3e-16 57.9 5.5 2.0 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family RVT_1 PF00078.27 EMR66586.1 - 2.9e-11 43.3 0.0 6.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3402 PF11882.8 EMR66587.1 - 3.7e-192 639.5 0.1 3.5e-158 527.5 0.0 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF3402) N1221 PF07923.13 EMR66587.1 - 1.8e-40 139.0 2.5 2.3e-33 115.6 1.3 2.8 3 0 0 3 3 3 2 N1221-like protein Spt20 PF12090.8 EMR66587.1 - 2.2 7.9 16.5 4.8 6.7 16.5 1.5 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 EMR66587.1 - 8.2 5.1 14.9 14 4.4 14.9 1.3 1 0 0 1 1 1 0 Androgen receptor DUF2011 PF09428.10 EMR66588.1 - 5.7e-20 71.4 1.6 9.9e-20 70.6 0.1 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) NDT80_PhoG PF05224.12 EMR66589.1 - 1.1e-32 113.8 0.0 1.1e-32 113.8 0.0 2.8 4 0 0 4 4 4 1 NDT80 / PhoG like DNA-binding family SUIM_assoc PF16619.5 EMR66589.1 - 0.00031 20.7 16.2 0.092 12.8 1.4 3.1 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 EMR66589.1 - 0.63 9.6 20.3 0.29 10.7 4.7 2.2 2 0 0 2 2 2 0 Spt20 family Hydin_ADK PF17213.3 EMR66589.1 - 1.3 9.2 13.1 0.52 10.6 0.5 2.7 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain DUF4834 PF16118.5 EMR66589.1 - 4.8 8.2 5.7 22 6.1 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SPO22 PF08631.10 EMR66590.1 - 5e-30 104.9 7.8 3.2e-23 82.6 0.1 3.9 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 EMR66590.1 - 0.054 13.6 2.5 52 4.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Sld5 PF05916.11 EMR66590.1 - 0.075 13.5 1.4 1.8 9.1 0.1 3.4 4 0 0 4 4 4 0 GINS complex protein DUF4128 PF13554.6 EMR66590.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Muted PF14942.6 EMR66590.1 - 0.62 10.4 4.8 0.54 10.6 0.3 2.5 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Sec6 PF06046.13 EMR66591.1 - 1.3e-168 562.0 10.0 2e-168 561.4 10.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 CUT PF02376.15 EMR66591.1 - 0.047 13.9 0.3 44 4.3 0.0 3.8 3 0 0 3 3 3 0 CUT domain NPV_P10 PF05531.12 EMR66591.1 - 0.058 13.9 5.7 15 6.2 0.1 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein OmdA PF13376.6 EMR66591.1 - 0.12 12.4 5.7 0.2 11.7 0.1 3.7 4 0 0 4 4 4 0 Bacteriocin-protection, YdeI or OmpD-Associated Vps53_N PF04100.12 EMR66591.1 - 0.48 9.3 13.2 0.0068 15.4 2.9 2.6 3 0 0 3 3 3 0 Vps53-like, N-terminal DUF745 PF05335.13 EMR66591.1 - 8 6.1 9.8 7.1 6.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF745) DUF104 PF01954.16 EMR66592.1 - 0.16 12.4 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 Abhydrolase_1 PF00561.20 EMR66593.1 - 2.3e-12 47.1 0.7 1.1e-10 41.6 0.9 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR66593.1 - 6.4e-09 35.4 0.2 9.2e-09 34.9 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR66593.1 - 2.6e-07 31.5 0.9 6.9e-07 30.1 0.2 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.14 EMR66593.1 - 0.044 13.1 0.3 0.067 12.5 0.3 1.2 1 0 0 1 1 1 0 Secretory lipase Thioesterase PF00975.20 EMR66593.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF3140 PF11338.8 EMR66594.1 - 2.6e-34 117.5 0.2 3e-34 117.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) TauD PF02668.16 EMR66595.1 - 3.2e-26 92.7 0.0 4.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CDH-cyt PF16010.5 EMR66596.1 - 2.6e-46 157.6 5.9 3e-46 157.4 5.9 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EMR66596.1 - 0.01 16.0 0.0 0.032 14.5 0.0 1.8 1 1 1 2 2 2 0 DOMON domain Acetyltransf_1 PF00583.25 EMR66598.1 - 0.017 15.4 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR66598.1 - 0.027 14.9 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR66598.1 - 0.03 14.4 0.0 0.08 13.1 0.0 1.7 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EMR66598.1 - 0.07 12.6 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 EMR66598.1 - 0.096 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_10 PF13673.7 EMR66598.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.19 EMR66599.1 - 4.2e-34 118.3 0.0 5.5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR66599.1 - 1.4e-30 106.7 0.0 2.3e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR66599.1 - 0.005 16.0 0.1 0.0081 15.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EMR66600.1 - 4.2e-08 32.8 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 EMR66600.1 - 0.00079 19.9 0.2 0.0017 18.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR66600.1 - 0.0029 16.9 0.2 0.015 14.6 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR66600.1 - 0.0093 16.2 0.2 0.028 14.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR66600.1 - 0.053 12.9 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Abhydrolase_6 PF12697.7 EMR66600.1 - 0.067 13.8 0.3 0.35 11.4 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family FAD_binding_2 PF00890.24 EMR66600.1 - 0.13 11.3 0.2 0.2 10.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EMR66600.1 - 0.27 10.4 0.2 0.48 9.6 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EHN PF06441.12 EMR66601.1 - 1e-37 128.8 1.5 1.1e-36 125.4 0.2 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMR66601.1 - 2.5e-12 47.0 0.1 4.5e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 EMR66602.1 - 7.6e-38 130.4 0.0 9.3e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EMR66603.1 - 2.2e-22 79.4 0.1 3.4e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMR66603.1 - 5.4e-22 77.7 0.0 8.8e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EMR66603.1 - 9.3e-09 36.4 0.0 1.6e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR66605.1 - 1.4e-23 83.4 0.0 1.2e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66605.1 - 6.6e-15 55.3 0.0 1.6e-12 47.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66605.1 - 1.6e-07 31.5 0.0 3.9e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMR66605.1 - 0.0004 19.9 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR66605.1 - 0.0061 16.0 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EMR66605.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fungal_lectin PF07938.12 EMR66606.1 - 5.2e-08 32.6 0.0 4.1e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Fungal fucose-specific lectin PhyH PF05721.13 EMR66607.1 - 6.5e-17 62.5 0.0 1e-16 61.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 EMR66608.1 - 5.9e-90 302.3 17.2 6.8e-90 302.1 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66608.1 - 1.3e-18 67.0 38.0 2.8e-17 62.7 21.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR66608.1 - 6.9e-06 24.9 20.3 0.00062 18.4 1.4 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein Glyco_hydro_61 PF03443.14 EMR66609.1 - 2.2e-54 184.5 0.0 2.7e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 EMR66610.1 - 2.1e-15 56.7 0.0 1.8e-12 47.1 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR66610.1 - 2.4e-05 24.3 0.2 6.4e-05 22.9 0.2 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR66610.1 - 0.094 12.2 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMR66610.1 - 0.097 11.7 0.1 0.62 9.1 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain LPMO_10 PF03067.15 EMR66611.1 - 1e-12 49.1 1.2 1.5e-12 48.6 1.2 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Opy2 PF09463.10 EMR66611.1 - 8 6.9 10.0 3.6 8.0 2.9 2.7 2 0 0 2 2 2 0 Opy2 protein MFS_1 PF07690.16 EMR66612.1 - 3.8e-30 105.0 34.7 7.9e-30 104.0 33.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMR66612.1 - 1.6e-06 27.7 4.0 1.6e-06 27.7 4.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 EMR66612.1 - 9.4 5.8 8.9 3.7 7.2 0.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) ThiJ_like PF17124.5 EMR66613.1 - 1.4e-63 214.1 0.0 1.8e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 EMR66613.1 - 3.1e-13 49.8 0.0 6.9e-12 45.5 0.0 2.6 1 1 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.19 EMR66613.1 - 0.0003 20.7 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EMR66613.1 - 0.066 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 EMR66614.1 - 1.6e-48 165.4 44.5 1.6e-48 165.4 44.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR66614.1 - 1.5e-17 63.3 21.3 2.1e-17 62.8 21.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMR66614.1 - 5e-14 52.0 9.6 5e-14 52.0 9.6 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 EMR66614.1 - 7e-05 21.4 0.8 7e-05 21.4 0.8 2.3 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 EMR66614.1 - 0.15 10.3 12.8 5.7 5.1 12.8 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_61 PF03443.14 EMR66616.1 - 1.6e-61 207.9 0.0 2.3e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4404 PF14357.6 EMR66617.1 - 0.026 15.2 0.6 0.044 14.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) ALAD PF00490.21 EMR66617.1 - 0.029 13.6 0.0 0.034 13.3 0.0 1.0 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase FlgN PF05130.12 EMR66617.1 - 0.042 14.4 1.4 1.5 9.3 0.6 2.1 1 1 1 2 2 2 0 FlgN protein RICH PF05062.12 EMR66617.1 - 0.045 14.1 0.5 0.31 11.4 0.0 2.3 2 0 0 2 2 2 0 RICH domain IZUMO PF15005.6 EMR66617.1 - 0.061 13.8 0.5 0.078 13.5 0.5 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated adh_short PF00106.25 EMR66618.1 - 3.4e-23 82.1 0.0 5.1e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66618.1 - 1.9e-17 63.7 0.0 2.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR66618.1 - 2.6e-05 23.8 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR66618.1 - 8.4e-05 22.6 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR66618.1 - 0.00041 20.3 0.0 0.001 19.0 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMR66618.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EMR66618.1 - 0.048 13.9 0.1 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain HAD_2 PF13419.6 EMR66619.1 - 3.4e-05 24.0 0.0 0.0019 18.3 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR66619.1 - 0.00065 20.0 0.0 0.29 11.4 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR66619.1 - 0.0054 16.8 0.1 0.015 15.4 0.1 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like TPR_16 PF13432.6 EMR66619.1 - 0.065 13.9 1.7 0.077 13.7 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat AflR PF08493.10 EMR66619.1 - 0.2 11.1 2.0 0.32 10.4 2.0 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Alpha-amylase PF00128.24 EMR66620.1 - 6.5e-108 361.3 0.0 8.8e-108 360.8 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EMR66620.1 - 0.046 12.8 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Delta_lysin PF05372.11 EMR66620.1 - 0.28 10.5 1.8 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Delta lysin family Mac PF12464.8 EMR66622.1 - 2.4e-19 69.3 0.0 5.5e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Fungal_trans_2 PF11951.8 EMR66622.1 - 2.3e-13 49.7 0.3 3.3e-13 49.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hexapep PF00132.24 EMR66622.1 - 6.1e-12 44.8 5.8 1.4e-10 40.4 3.6 2.4 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMR66622.1 - 9e-11 41.3 4.4 5.4e-08 32.4 2.9 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase PDR_CDR PF06422.12 EMR66623.1 - 2 8.3 7.6 0.97 9.4 2.7 2.6 2 1 1 3 3 3 0 CDR ABC transporter DUF1996 PF09362.10 EMR66624.1 - 1.7e-70 237.6 0.9 2.2e-70 237.3 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ribosomal_60s PF00428.19 EMR66625.1 - 0.2 12.3 6.0 0.27 11.8 0.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein POPLD PF08170.12 EMR66626.1 - 6e-30 103.4 1.0 2.2e-29 101.6 0.0 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain Aldo_ket_red PF00248.21 EMR66628.1 - 1.3e-41 142.8 0.0 1.4e-39 136.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MASE1 PF05231.14 EMR66629.1 - 0.022 13.9 0.2 0.036 13.2 0.2 1.2 1 0 0 1 1 1 0 MASE1 NT-C2 PF10358.9 EMR66630.1 - 1.5e-22 79.9 0.0 8.6e-18 64.5 0.0 2.3 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins SNARE PF05739.19 EMR66631.1 - 6e-14 51.8 0.1 1.7e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EMR66631.1 - 1e-10 40.5 8.4 8.3e-10 37.6 1.7 2.6 2 0 0 2 2 2 2 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 EMR66631.1 - 0.0053 16.5 0.4 0.0053 16.5 0.4 2.5 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.21 EMR66631.1 - 0.0054 16.6 4.4 0.26 11.1 1.1 2.3 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-18_N PF10496.9 EMR66631.1 - 0.029 14.6 0.5 0.26 11.5 0.1 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Prominin PF05478.11 EMR66631.1 - 0.2 9.6 0.5 1.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Prominin UPF0242 PF06785.11 EMR66631.1 - 2.3 8.3 6.6 1.2 9.2 0.7 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Use1 PF09753.9 EMR66631.1 - 8.6 6.0 11.0 0.93 9.2 0.4 2.8 2 1 0 3 3 3 0 Membrane fusion protein Use1 GMC_oxred_N PF00732.19 EMR66632.1 - 3.5e-61 207.2 0.0 4.6e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR66632.1 - 7.4e-31 107.6 0.0 1.3e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 EMR66632.1 - 0.00011 21.6 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR66632.1 - 0.00063 19.9 0.1 0.0014 18.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR66632.1 - 0.0011 18.2 0.2 0.023 13.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EMR66632.1 - 0.0018 17.4 0.3 0.0065 15.6 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 EMR66632.1 - 0.0034 16.2 0.1 0.2 10.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EMR66632.1 - 0.0047 16.2 0.0 0.85 8.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR66632.1 - 0.014 15.0 0.9 0.081 12.5 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EMR66632.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.12 EMR66633.1 - 3.7e-16 59.6 0.0 7.1e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR66633.1 - 5.6e-16 58.8 0.0 1.1e-15 57.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR66633.1 - 6.4e-15 55.3 0.0 8.5e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR66633.1 - 1.3e-14 54.7 0.0 2.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR66633.1 - 9.3e-08 31.7 0.0 8.3e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMR66633.1 - 3.1e-07 31.1 0.0 5.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMR66633.1 - 4.9e-07 29.3 0.0 7e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EMR66633.1 - 0.00061 19.4 0.0 0.0013 18.3 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase small domain Couple_hipA PF13657.6 EMR66633.1 - 0.0011 19.5 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 HipA N-terminal domain MetW PF07021.12 EMR66633.1 - 0.0021 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 EMR66633.1 - 0.022 14.2 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 EMR66633.1 - 0.038 12.9 0.1 0.077 11.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 EMR66633.1 - 0.07 13.1 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EMR66633.1 - 0.088 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HSP70 PF00012.20 EMR66634.1 - 1e-79 268.3 1.0 1.3e-79 268.0 1.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMR66634.1 - 6.9e-06 25.1 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein CsgE PF10627.9 EMR66634.1 - 0.022 15.0 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 Curli assembly protein CsgE YbaB_DNA_bd PF02575.16 EMR66634.1 - 0.081 13.2 1.9 0.25 11.6 0.1 2.6 4 0 0 4 4 4 0 YbaB/EbfC DNA-binding family Rrp40_N PF18311.1 EMR66635.1 - 5.2e-19 67.9 4.3 5.5e-19 67.8 0.9 2.6 3 0 0 3 3 3 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 EMR66635.1 - 1.8e-15 57.0 0.0 5.1e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 KH domain Lipase_GDSL PF00657.22 EMR66636.1 - 2.2e-11 44.1 0.0 2.6e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EMR66636.1 - 0.00012 22.5 2.7 0.00039 20.9 2.7 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family p450 PF00067.22 EMR66638.1 - 1.8e-74 251.2 0.0 2.4e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EMR66639.1 - 4.9e-49 167.3 0.0 6.2e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GYF PF02213.16 EMR66640.1 - 2.5e-11 43.1 1.4 6.3e-11 41.8 1.4 1.7 1 0 0 1 1 1 1 GYF domain Herpes_US9 PF06072.11 EMR66640.1 - 0.038 13.9 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Fib_alpha PF08702.10 EMR66641.1 - 0.00034 20.8 2.8 0.00034 20.8 2.8 7.0 3 2 2 7 7 6 4 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EMR66641.1 - 0.0018 17.2 3.7 0.0018 17.2 3.7 5.9 2 2 3 6 6 5 2 Spc7 kinetochore protein MscS_porin PF12795.7 EMR66641.1 - 0.002 17.7 30.3 0.002 17.7 30.3 4.9 4 1 1 5 5 5 1 Mechanosensitive ion channel porin domain GAS PF13851.6 EMR66641.1 - 0.0028 17.0 2.9 0.0028 17.0 2.9 6.7 4 3 3 7 7 6 4 Growth-arrest specific micro-tubule binding Lipase_GDSL PF00657.22 EMR66641.1 - 0.006 16.6 7.9 0.0096 15.9 0.7 3.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase CorA PF01544.18 EMR66641.1 - 0.012 15.0 27.7 0.015 14.6 9.6 4.7 4 1 1 5 5 5 0 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.20 EMR66641.1 - 0.02 14.8 0.6 0.02 14.8 0.6 10.5 7 4 2 10 10 9 0 Prefoldin subunit FlaC_arch PF05377.11 EMR66641.1 - 0.021 15.2 37.3 0.17 12.3 0.9 8.6 7 2 3 10 10 10 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 EMR66641.1 - 0.13 12.5 25.4 0.99 9.7 1.1 6.2 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 EMR66641.1 - 0.21 10.9 63.9 0.44 9.8 17.5 4.5 2 2 2 4 4 4 0 Domain of unknown function (DUF4407) DASH_Dam1 PF08653.10 EMR66641.1 - 0.22 11.3 2.6 21 5.0 0.1 4.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 LPP PF04728.13 EMR66641.1 - 0.42 11.0 0.1 0.34 11.3 0.2 7.5 8 2 2 10 10 7 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 EMR66641.1 - 1.2 9.2 55.5 0.023 14.7 5.2 7.5 5 2 3 8 8 8 0 Protein of unknown function (DUF1664) Myb_DNA-bind_4 PF13837.6 EMR66642.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Gp_dh_C PF02800.20 EMR66643.1 - 2.3e-73 245.0 0.1 3.5e-73 244.4 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EMR66643.1 - 2.2e-39 133.9 0.2 4.9e-39 132.8 0.2 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EMR66643.1 - 0.009 16.1 0.6 0.044 13.9 0.4 2.4 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus TTC5_OB PF16669.5 EMR66643.1 - 0.12 12.1 0.1 2.4 7.9 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat protein 5 OB fold domain TFR_dimer PF04253.15 EMR66644.1 - 4.1e-21 75.3 0.0 7.7e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EMR66644.1 - 9e-21 74.5 0.0 1.7e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMR66644.1 - 1.1e-08 34.9 0.2 5.7e-08 32.7 0.1 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EMR66644.1 - 0.035 13.8 0.0 0.091 12.4 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 UFD1 PF03152.14 EMR66646.1 - 5.2e-68 227.9 0.1 6.6e-68 227.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 EMR66646.1 - 0.2 11.9 0.0 0.56 10.4 0.0 1.8 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Pyr_redox_3 PF13738.6 EMR66648.1 - 6.1e-24 84.8 0.0 4e-20 72.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR66648.1 - 1.8e-21 76.6 0.0 2e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR66648.1 - 2.9e-17 62.8 0.0 3.3e-13 49.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EMR66648.1 - 1e-15 57.2 0.0 1.8e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 EMR66648.1 - 2.1e-10 41.0 0.0 0.033 14.7 0.0 3.4 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR66648.1 - 2.7e-08 33.9 0.5 0.018 15.0 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EMR66648.1 - 3.9e-08 32.9 0.9 3.3e-06 26.6 0.3 2.4 1 1 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 EMR66648.1 - 6e-07 29.6 0.0 0.002 18.2 0.0 3.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 EMR66648.1 - 8.6e-06 25.9 0.0 4e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EMR66648.1 - 1.1e-05 24.7 0.5 0.33 10.0 0.0 3.3 3 1 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 EMR66648.1 - 1.6e-05 24.6 1.7 0.42 10.1 0.0 3.7 3 2 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR66648.1 - 6.4e-05 22.2 0.4 0.016 14.3 0.0 3.1 3 1 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EMR66648.1 - 6.9e-05 22.3 0.0 0.064 12.6 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EMR66648.1 - 0.00015 21.0 0.0 0.015 14.4 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein F420_oxidored PF03807.17 EMR66648.1 - 0.0011 19.5 0.0 1.7 9.3 0.0 3.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 EMR66648.1 - 0.0018 17.1 0.1 0.22 10.2 0.0 3.1 4 0 0 4 4 4 1 HI0933-like protein FAD_oxidored PF12831.7 EMR66648.1 - 0.0052 16.2 0.0 0.21 10.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EMR66648.1 - 0.0096 15.8 0.0 0.8 9.6 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 EMR66648.1 - 0.011 15.1 0.3 1.1 8.5 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 EMR66648.1 - 0.02 15.3 0.0 0.85 10.1 0.0 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding ApbA PF02558.16 EMR66648.1 - 0.054 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EMR66648.1 - 0.094 12.1 0.0 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 ThiF family NitrOD2 PF18550.1 EMR66648.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Nitrososphaera output domain 2 AlaDh_PNT_C PF01262.21 EMR66648.1 - 0.14 11.4 0.0 17 4.6 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TIP49 PF06068.13 EMR66649.1 - 3.7e-152 506.6 1.2 4.6e-152 506.3 1.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EMR66649.1 - 5.1e-20 71.4 0.3 1.9e-19 69.5 0.2 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EMR66649.1 - 9.2e-08 32.6 0.2 5.6e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMR66649.1 - 3e-07 30.3 0.5 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EMR66649.1 - 3.2e-06 26.7 0.5 5.5e-06 25.9 0.5 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EMR66649.1 - 0.0001 22.8 1.0 0.00021 21.7 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EMR66649.1 - 0.00095 18.6 0.8 0.0089 15.4 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EMR66649.1 - 0.018 15.3 0.1 2.3 8.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EMR66649.1 - 0.02 15.2 1.9 1 9.7 1.9 2.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EMR66649.1 - 0.034 13.9 0.0 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 EMR66649.1 - 0.042 13.6 0.6 0.34 10.7 0.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMR66649.1 - 0.057 13.4 0.1 3.7 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EMR66649.1 - 0.059 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMR66649.1 - 0.078 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMR66649.1 - 0.18 11.3 0.2 0.68 9.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region p450 PF00067.22 EMR66651.1 - 5.3e-44 150.7 0.0 6.7e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2785 PF10978.8 EMR66652.1 - 0.0039 17.0 0.4 0.0048 16.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2785) p450 PF00067.22 EMR66653.1 - 3e-40 138.4 0.0 4.7e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HTH_12 PF08461.10 EMR66655.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Trypan_PARP PF05887.11 EMR66655.1 - 1.5 8.8 16.8 2.5 8.1 16.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) p450 PF00067.22 EMR66656.1 - 4.2e-27 95.0 0.0 9.3e-27 93.9 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 DUF917 PF06032.12 EMR66657.1 - 1.7e-124 415.2 1.1 1.7e-124 415.2 1.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EMR66657.1 - 4.2e-34 118.1 7.7 2.4e-31 109.1 0.1 3.8 3 1 1 4 4 4 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMR66657.1 - 1.3e-26 93.4 6.9 6.5e-26 91.1 0.0 3.3 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 EMR66657.1 - 5.1e-05 22.9 5.6 0.0012 18.5 0.1 3.0 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 EMR66657.1 - 0.0007 18.3 5.5 0.0025 16.5 0.0 2.7 3 0 0 3 3 3 2 MutL protein StbA PF06406.11 EMR66657.1 - 0.0092 15.3 0.5 2 7.6 0.0 2.4 2 0 0 2 2 2 2 StbA protein ROK PF00480.20 EMR66657.1 - 0.013 15.0 0.0 0.048 13.1 0.0 2.0 1 0 0 1 1 1 0 ROK family DUF1640 PF07798.11 EMR66658.1 - 7.6e-46 156.3 9.1 8.5e-46 156.2 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 EMR66658.1 - 0.0046 16.4 0.9 0.0079 15.6 0.1 1.6 1 1 1 2 2 2 1 GNAT acetyltransferase 2 Peptidase_S46 PF10459.9 EMR66658.1 - 0.02 13.5 1.9 0.023 13.3 1.9 1.0 1 0 0 1 1 1 0 Peptidase S46 Cluap1 PF10234.9 EMR66658.1 - 0.053 12.9 7.6 0.067 12.6 7.6 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 XhlA PF10779.9 EMR66658.1 - 0.31 11.3 0.2 0.31 11.3 0.2 2.6 3 0 0 3 3 3 0 Haemolysin XhlA BST2 PF16716.5 EMR66658.1 - 1.5 9.5 13.6 0.47 11.1 1.5 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FapA PF03961.13 EMR66658.1 - 1.5 7.3 6.2 1.7 7.1 6.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A BshC PF10079.9 EMR66658.1 - 1.9 7.1 8.1 0.53 9.0 1.2 2.0 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC Uso1_p115_C PF04871.13 EMR66658.1 - 2.3 8.6 12.1 1.6 9.1 1.9 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nas2_N PF18265.1 EMR66658.1 - 3.8 7.5 6.8 5.5 7.0 0.2 2.7 3 0 0 3 3 3 0 Nas2 N_terminal domain TMPIT PF07851.13 EMR66658.1 - 7.4 5.7 7.2 0.88 8.7 0.9 1.9 1 1 1 2 2 2 0 TMPIT-like protein Lactamase_B_2 PF12706.7 EMR66659.1 - 4.2e-28 98.2 0.0 2.2e-26 92.6 0.0 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMR66659.1 - 3e-11 43.5 0.0 5.7e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMR66659.1 - 2e-07 31.2 0.0 1.3e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily MPC PF03650.13 EMR66660.1 - 2.8e-33 114.3 0.0 3.4e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Glyco_transf_15 PF01793.16 EMR66661.1 - 1e-132 442.4 8.0 1.2e-132 442.1 8.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Clathrin PF00637.20 EMR66662.1 - 3.2e-197 646.3 28.7 2.6e-32 111.7 1.9 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EMR66662.1 - 8.2e-32 108.9 0.1 4.6e-31 106.5 0.0 2.4 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 EMR66662.1 - 1.4e-31 107.2 1.2 2.6e-05 24.3 0.1 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat TPR_7 PF13176.6 EMR66662.1 - 1.8e-05 24.4 4.6 8.5 6.7 0.1 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMR66662.1 - 0.00077 20.1 10.5 5.9 8.0 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat Clathrin-link PF09268.10 EMR66662.1 - 0.0073 15.6 0.1 0.074 12.4 0.1 2.5 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_12 PF13424.6 EMR66662.1 - 0.012 15.9 1.5 24 5.3 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMR66662.1 - 0.037 14.3 7.9 0.4 11.0 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EMR66662.1 - 0.075 12.1 7.9 8.3 5.3 0.3 4.7 5 0 0 5 5 5 0 Coatomer WD associated region Vps39_1 PF10366.9 EMR66662.1 - 0.31 11.3 7.8 7.7 6.8 0.0 5.8 5 2 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 EMR66662.1 - 0.99 9.7 10.4 7.2 7.0 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMR66662.1 - 1.3 9.0 9.1 6.6 6.7 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L5_C PF00673.21 EMR66664.1 - 4.6e-22 78.0 0.0 6.7e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EMR66664.1 - 9.5e-19 67.5 0.0 2.8e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Sin_N PF04801.13 EMR66665.1 - 3.7e-21 75.8 0.0 2.9e-20 72.9 0.0 2.0 1 1 0 1 1 1 1 Sin-like protein conserved region LSM PF01423.22 EMR66666.1 - 1.5e-18 66.3 0.0 2.1e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EMR66666.1 - 0.25 11.0 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Hfq protein RRM_1 PF00076.22 EMR66667.1 - 0.0052 16.6 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGAP PF00620.27 EMR66668.1 - 1.6e-43 148.2 0.4 3.3e-43 147.1 0.4 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EMR66668.1 - 2.3e-12 47.4 0.0 5.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EMR66668.1 - 0.0099 16.1 0.0 0.097 13.0 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Fanconi_A_N PF15865.5 EMR66668.1 - 0.12 11.8 1.4 0.2 11.0 1.4 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus NAD_binding_9 PF13454.6 EMR66669.1 - 2.1e-05 24.5 0.9 0.11 12.5 0.1 2.7 2 1 1 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EMR66669.1 - 0.00064 19.1 1.3 0.0082 15.4 1.3 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR66669.1 - 0.00072 18.9 1.6 0.03 13.5 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR66669.1 - 0.00074 19.7 0.2 0.0023 18.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR66669.1 - 0.0011 18.2 0.1 0.62 9.0 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.24 EMR66669.1 - 0.0077 15.6 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EMR66669.1 - 0.017 15.6 0.4 0.51 10.9 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR66669.1 - 0.064 12.8 0.9 0.13 11.9 0.9 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Rossmann-like PF10727.9 EMR66669.1 - 0.098 12.5 0.3 0.2 11.5 0.3 1.5 1 0 0 1 1 1 0 Rossmann-like domain PAT1 PF09770.9 EMR66670.1 - 0 1175.7 0.5 0 1175.4 0.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Transp_cyt_pur PF02133.15 EMR66671.1 - 3.8e-80 269.8 38.9 5.6e-80 269.3 38.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2516 PF10724.9 EMR66671.1 - 3.5 8.0 8.6 4.4 7.7 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) MFS_1 PF07690.16 EMR66672.1 - 1.2 8.0 7.0 0.37 9.6 0.3 2.1 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF5504 PF17608.2 EMR66673.1 - 9 6.4 20.1 0.99 9.5 3.2 3.2 1 1 2 3 3 3 0 Family of unknown function (DUF5504) Abhydrolase_1 PF00561.20 EMR66674.1 - 2.8e-05 23.9 0.0 3.8e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR66674.1 - 0.0026 18.4 0.3 0.011 16.3 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR66674.1 - 0.025 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RNA_ligase PF09414.10 EMR66675.1 - 1.7e-25 90.2 0.0 3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Abhydrolase_6 PF12697.7 EMR66676.1 - 6.6e-16 59.6 0.5 7.9e-16 59.3 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR66676.1 - 2.4e-08 33.9 0.2 5.2e-05 23.0 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR66676.1 - 9.6e-08 31.6 0.0 0.0037 16.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMR66676.1 - 0.00028 20.4 0.0 0.047 13.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 EMR66676.1 - 0.002 16.8 0.0 0.067 11.9 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 EMR66676.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 EMR66676.1 - 0.086 12.4 0.0 0.58 9.7 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 EMR66676.1 - 0.13 12.3 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain adh_short_C2 PF13561.6 EMR66677.1 - 9.9e-22 77.6 2.3 1.2e-21 77.3 2.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR66677.1 - 5.9e-17 61.8 0.1 8.1e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR66677.1 - 0.00025 21.0 0.9 0.00039 20.4 0.9 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 EMR66677.1 - 0.028 14.8 0.1 0.051 14.0 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 EMR66677.1 - 0.052 12.9 1.0 0.069 12.5 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EMR66677.1 - 0.11 12.0 2.5 0.38 10.2 0.3 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMR66678.1 - 1.1e-27 97.1 0.0 1.6e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR66678.1 - 7.6e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMR66678.1 - 3e-05 24.3 0.2 0.00093 19.5 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EMR66678.1 - 0.00071 19.7 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EMR66678.1 - 0.0011 19.3 0.2 0.0027 18.2 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EMR66678.1 - 0.025 14.0 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PDR_assoc PF08370.11 EMR66678.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Glyco_hydro_43 PF04616.14 EMR66679.1 - 5.5e-60 203.1 0.2 6.9e-60 202.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EMR66679.1 - 0.0004 20.2 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Peptidase_M20 PF01546.28 EMR66680.1 - 1.2e-20 74.2 0.1 1.7e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EMR66680.1 - 0.0036 17.0 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 EMR66680.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain TraW_N PF12477.8 EMR66680.1 - 0.16 12.0 0.6 0.45 10.5 0.6 1.8 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Hce2 PF14856.6 EMR66681.1 - 2.1e-09 37.6 0.0 2.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor RTA1 PF04479.13 EMR66682.1 - 1.6e-71 240.2 11.7 2.2e-71 239.7 11.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.12 EMR66682.1 - 2.3 8.1 18.4 0.21 11.5 3.3 3.1 2 2 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component HemY_N PF07219.13 EMR66682.1 - 6.2 7.1 6.0 32 4.8 0.2 3.4 4 0 0 4 4 4 0 HemY protein N-terminus Peptidase_S8 PF00082.22 EMR66684.1 - 1.6e-29 103.1 7.5 1.9e-29 102.9 7.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR66684.1 - 0.0014 19.3 0.1 0.0056 17.3 0.1 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 RRM_1 PF00076.22 EMR66684.1 - 0.15 11.9 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AKAP2_C PF15304.6 EMR66685.1 - 0.046 13.0 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Glyco_transf_92 PF01697.27 EMR66685.1 - 0.067 12.8 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 TRI12 PF06609.13 EMR66686.1 - 1.8e-129 432.9 33.5 9.2e-79 265.4 7.5 3.0 1 1 2 3 3 3 3 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EMR66686.1 - 2.3e-15 56.4 43.8 2.3e-15 56.4 43.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR66686.1 - 4.9e-11 42.1 6.8 4.9e-11 42.1 6.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Tmemb_18A PF09771.9 EMR66686.1 - 4 7.8 5.1 50 4.3 1.0 2.7 2 0 0 2 2 2 0 Transmembrane protein 188 DUF3671 PF12420.8 EMR66686.1 - 4.7 7.3 6.4 5.1 7.2 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function ADH_N PF08240.12 EMR66687.1 - 8.2e-27 93.2 1.0 1.4e-26 92.5 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR66687.1 - 2.5e-19 69.5 0.7 5.8e-19 68.4 0.7 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR66687.1 - 9.9e-18 65.5 0.3 2.2e-17 64.4 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DHHC PF01529.20 EMR66687.1 - 3.9 7.6 4.9 6.3 6.9 4.9 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Prim_Zn_Ribbon PF08273.12 EMR66689.1 - 0.1 12.9 0.7 5.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Sugar_tr PF00083.24 EMR66690.1 - 7.9e-69 232.7 19.7 9.2e-68 229.1 19.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66690.1 - 2.2e-15 56.5 31.1 3e-10 39.6 9.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR66690.1 - 6.5e-05 22.0 8.0 0.00032 19.7 0.9 2.6 1 1 1 2 2 2 2 MFS_1 like family PspC PF04024.12 EMR66690.1 - 9.1 6.2 7.7 1.5 8.7 0.5 3.1 3 0 0 3 3 3 0 PspC domain NUDIX_2 PF13869.6 EMR66691.1 - 8e-81 270.1 0.0 9.5e-81 269.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase PDEase_I PF00233.19 EMR66692.1 - 1.7e-67 227.6 0.0 2.4e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase UPF0047 PF01894.17 EMR66693.1 - 6.2e-37 126.3 0.0 7.8e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 CAP_N PF01213.19 EMR66693.1 - 0.06 12.8 1.5 0.078 12.4 1.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 EMR66694.1 - 3.8e-48 164.1 0.0 4.5e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR66694.1 - 1.3e-15 57.4 0.0 1.7e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR66694.1 - 1.2e-08 34.6 0.0 1.9e-08 34.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EMR66694.1 - 4.1e-05 22.7 0.0 5.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EMR66694.1 - 0.00013 21.7 0.4 0.00024 20.7 0.1 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EMR66694.1 - 0.00036 20.5 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EMR66694.1 - 0.00037 19.9 0.1 0.00065 19.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMR66694.1 - 0.00079 18.3 0.0 0.00096 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Peptidase_M16_M PF16187.5 EMR66695.1 - 1.8e-95 319.4 0.1 2.8e-95 318.8 0.1 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EMR66695.1 - 5.7e-33 114.0 0.9 2.2e-32 112.1 0.0 2.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMR66695.1 - 1.8e-32 112.9 0.1 1.7e-19 70.5 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain UCH PF00443.29 EMR66696.1 - 1.1e-53 182.4 0.1 1.4e-53 182.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMR66696.1 - 4.2e-09 36.4 0.0 4.4e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Zn_ribbon_SprT PF17283.2 EMR66696.1 - 0.63 10.0 2.3 1.5 8.8 0.3 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-ribbon_3 PF13248.6 EMR66696.1 - 0.82 9.2 4.0 3.5 7.2 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Dynamin_N PF00350.23 EMR66697.1 - 9.8e-14 51.8 1.0 1.1e-12 48.3 0.0 3.0 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EMR66697.1 - 5.1e-06 26.5 0.2 0.0025 17.9 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR66697.1 - 0.00012 22.1 0.0 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EMR66697.1 - 0.0032 18.0 3.1 0.0032 18.0 3.1 4.1 3 2 0 3 3 3 1 ABC transporter AAA_22 PF13401.6 EMR66697.1 - 0.012 15.8 0.1 0.18 12.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain CttA_N PF18244.1 EMR66697.1 - 0.026 15.0 2.6 4.7 7.7 0.1 3.1 3 0 0 3 3 3 0 Cellulose-binding protein CttA N-terminal domain Rsbr_N PF08678.10 EMR66697.1 - 0.066 13.3 1.5 0.26 11.4 0.1 2.8 3 0 0 3 3 2 0 Rsbr N terminal Adeno_IVa2 PF02456.15 EMR66697.1 - 0.079 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.6 EMR66697.1 - 0.1 12.4 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PSK_trans_fac PF07704.11 EMR66697.1 - 0.18 12.5 3.3 2.9 8.7 0.0 3.5 2 1 0 2 2 2 0 Rv0623-like transcription factor RNA_helicase PF00910.22 EMR66697.1 - 0.36 11.2 1.8 3.8 7.9 0.0 3.3 3 0 0 3 3 3 0 RNA helicase GTP_EFTU PF00009.27 EMR66697.1 - 0.36 10.3 0.0 0.36 10.3 0.0 2.8 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran_CTD PF16326.5 EMR66697.1 - 1.8 8.8 9.5 0.9 9.8 2.9 3.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain Tma16 PF11176.8 EMR66697.1 - 7.3 6.5 13.0 0.46 10.4 7.1 2.1 2 0 0 2 2 2 0 Translation machinery-associated protein 16 zf-CHCC PF10276.9 EMR66698.1 - 1.1e-10 41.3 0.1 1.7e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger domain Cytomega_UL84 PF06284.11 EMR66698.1 - 0.084 11.3 0.2 0.11 10.9 0.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Glyco_hydro_31 PF01055.26 EMR66699.1 - 1.1e-149 499.4 2.0 1.3e-149 499.1 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 FAD_binding_2 PF00890.24 EMR66700.1 - 1e-33 117.0 0.0 1.5e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR66700.1 - 0.00039 20.1 0.1 0.0049 16.5 0.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR66700.1 - 0.0035 16.6 0.0 0.03 13.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase LPD22 PF18834.1 EMR66700.1 - 0.015 15.4 0.0 0.043 14.0 0.0 1.7 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 EthD PF07110.11 EMR66701.1 - 4.9e-08 34.0 0.1 5.2e-08 33.9 0.1 1.0 1 0 0 1 1 1 1 EthD domain EcoEI_R_C PF08463.10 EMR66701.1 - 0.056 13.5 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 EcoEI R protein C-terminal Tannase PF07519.11 EMR66702.1 - 7.2e-95 318.6 0.2 1.1e-94 318.0 0.2 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase KR PF08659.10 EMR66702.1 - 1.1e-58 198.1 0.1 3.5e-58 196.5 0.0 2.0 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.21 EMR66702.1 - 2.9e-49 168.3 0.2 5.6e-49 167.4 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EMR66702.1 - 3e-39 135.1 0.1 5.2e-39 134.3 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EMR66702.1 - 3.9e-38 130.1 0.1 1.1e-37 128.6 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EMR66702.1 - 2.8e-37 128.6 0.0 2e-25 89.8 0.0 2.8 2 1 1 3 3 2 2 Beta-ketoacyl synthase, N-terminal domain Methyltransf_12 PF08242.12 EMR66702.1 - 8e-21 74.6 0.0 2.4e-20 73.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EMR66702.1 - 1.7e-15 57.4 0.0 1.1e-14 54.9 0.0 2.3 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EMR66702.1 - 3.9e-15 55.8 0.3 2.4e-14 53.3 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 EMR66702.1 - 2.3e-13 50.7 0.1 2.7e-12 47.2 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR66702.1 - 1.1e-12 48.1 0.0 3.7e-12 46.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EMR66702.1 - 1.8e-12 48.5 0.0 8e-11 43.1 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 EMR66702.1 - 1.1e-11 44.8 0.0 3e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR66702.1 - 6.4e-11 42.8 0.0 2.4e-10 40.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EMR66702.1 - 3.8e-09 36.6 7.9 1.3e-07 31.7 0.2 4.6 4 1 0 4 4 4 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 EMR66702.1 - 1.4e-08 34.6 0.1 5.2e-08 32.7 0.0 2.0 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 EMR66702.1 - 1.1e-06 28.2 0.0 3.2e-06 26.7 0.0 1.7 2 0 0 2 2 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 EMR66702.1 - 4.9e-06 26.8 0.0 1.5e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EMR66702.1 - 0.0024 17.8 0.1 0.0075 16.1 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PIF1 PF05970.14 EMR66702.1 - 0.0032 16.7 0.0 0.0057 15.9 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Methyltransf_16 PF10294.9 EMR66702.1 - 0.02 14.6 0.0 0.06 13.1 0.0 1.8 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 EMR66702.1 - 0.023 15.7 0.0 0.098 13.7 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.15 EMR66702.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAS PF03059.16 EMR66702.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Nicotianamine synthase protein UvrD_C_2 PF13538.6 EMR66702.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Methyltransf_28 PF02636.17 EMR66702.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 EMR66704.1 - 2.1e-11 43.9 0.0 6e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR66704.1 - 3.3e-07 30.8 0.0 1.5e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR66704.1 - 1.3e-06 29.0 0.0 6.5e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR66704.1 - 1.5e-05 25.7 0.0 4.1e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR66704.1 - 0.00015 21.2 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EMR66704.1 - 0.003 17.4 0.0 0.009 15.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Kelch_5 PF13854.6 EMR66707.1 - 8.3e-14 51.2 0.5 8.9e-10 38.3 0.2 3.2 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 EMR66707.1 - 1.7e-05 24.9 3.0 0.093 13.1 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EMR66707.1 - 0.0036 17.2 8.5 2.7 8.1 0.3 4.4 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 EMR66707.1 - 0.0064 16.1 5.3 4.2 7.0 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 EMR66707.1 - 0.019 15.0 10.9 2.1 8.4 0.5 4.0 2 2 1 3 3 3 0 Galactose oxidase, central domain Kelch_3 PF13415.6 EMR66707.1 - 0.23 11.8 0.1 0.23 11.8 0.1 4.7 6 1 0 6 6 6 0 Galactose oxidase, central domain MtrG PF04210.13 EMR66708.1 - 0.15 11.9 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Glyco_hydro_6 PF01341.17 EMR66709.1 - 3e-97 326.0 0.6 3.9e-97 325.7 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 MFS_1 PF07690.16 EMR66710.1 - 1e-06 28.0 7.2 8.7e-06 24.9 6.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 EMR66712.1 - 4.3e-15 56.0 12.6 5.2e-15 55.7 12.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain T4SS_CagC PF16943.5 EMR66712.1 - 0.06 13.5 0.2 2 8.6 0.1 2.2 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system MFS_1 PF07690.16 EMR66713.1 - 1.8e-10 40.3 9.5 2.3e-05 23.5 1.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OST3_OST6 PF04756.13 EMR66714.1 - 2.2e-101 339.1 0.0 2.7e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EMR66714.1 - 0.0049 16.8 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HisKA_7TM PF16927.5 EMR66714.1 - 0.067 13.2 3.6 0.13 12.2 3.6 1.5 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase DUF3995 PF13160.6 EMR66714.1 - 0.1 13.0 3.5 0.61 10.5 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) SbcCD_C PF13558.6 EMR66715.1 - 0.11 12.8 1.8 0.18 12.1 0.6 1.8 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF4325 PF14213.6 EMR66716.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Sugar_tr PF00083.24 EMR66717.1 - 2.9e-82 277.0 13.7 1.6e-53 182.2 4.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR66717.1 - 2e-19 69.8 29.4 2.7e-14 52.9 1.9 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 EMR66717.1 - 0.38 11.0 7.4 1.2 9.4 2.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Phage_holin_3_2 PF04550.12 EMR66717.1 - 0.55 10.8 4.4 0.24 12.0 0.7 2.2 2 0 0 2 2 2 0 Phage holin family 2 MFS_1 PF07690.16 EMR66718.1 - 6.1e-39 133.9 34.3 6.1e-39 133.9 34.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2721 PF11026.8 EMR66718.1 - 0.35 10.8 0.1 0.35 10.8 0.1 4.2 3 2 1 4 4 4 0 Protein of unknown function (DUF2721) Pkinase PF00069.25 EMR66720.1 - 1.6e-48 165.4 0.0 3.7e-46 157.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR66720.1 - 3e-26 92.2 0.0 1.2e-25 90.3 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase DIOX_N PF14226.6 EMR66721.1 - 1.6e-25 90.1 0.1 2.7e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR66721.1 - 5.4e-12 46.1 0.0 1.1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.26 EMR66723.1 - 4e-47 159.4 0.0 4.5e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMR66723.1 - 0.019 14.7 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EMR66723.1 - 0.055 13.8 0.3 0.1 12.9 0.3 1.5 1 1 0 1 1 1 0 RWD domain AIM24 PF01987.17 EMR66725.1 - 5.5e-47 160.2 0.2 7e-47 159.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ndc1_Nup PF09531.10 EMR66725.1 - 0.078 11.7 0.8 0.071 11.8 0.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 EMR66725.1 - 5.1 7.0 25.1 7.2 6.5 25.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MetOD2 PF18548.1 EMR66726.1 - 0.096 12.8 38.9 0.79 9.9 3.5 5.6 4 2 1 5 5 5 0 Metanogen output domain 2 Ureidogly_lyase PF04115.12 EMR66727.1 - 5.2e-54 182.9 0.0 6.7e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase SANT_DAMP1_like PF16282.5 EMR66728.1 - 6.3e-32 109.6 1.0 1.3e-31 108.6 1.0 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Gag_p17 PF00540.18 EMR66728.1 - 0.4 10.7 0.0 0.4 10.7 0.0 2.9 3 0 0 3 3 3 0 gag gene protein p17 (matrix protein) MRC1 PF09444.10 EMR66729.1 - 5.9e-42 143.6 18.7 5.9e-42 143.6 18.7 9.0 7 2 2 9 9 9 1 MRC1-like domain Gly_rich PF12810.7 EMR66729.1 - 0.025 14.5 11.6 0.068 13.1 11.6 1.8 1 0 0 1 1 1 0 Glycine rich protein DUF3446 PF11928.8 EMR66731.1 - 9.9 6.5 12.9 18 5.7 2.6 3.2 3 0 0 3 3 3 0 Early growth response N-terminal domain Med1 PF10744.9 EMR66732.1 - 2.7e-100 336.3 0.0 4e-100 335.8 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DAG_kinase_N PF14513.6 EMR66732.1 - 0.27 11.4 1.4 0.5 10.6 1.4 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Cyt-b5 PF00173.28 EMR66733.1 - 1.8e-14 53.6 0.0 9.8e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.20 EMR66733.1 - 1.7e-11 44.2 0.0 4.2e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain IDO PF01231.18 EMR66733.1 - 2.7e-11 42.9 0.0 3.6e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.21 EMR66733.1 - 3.8e-08 33.9 0.0 1.4e-07 32.1 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Mucin PF01456.17 EMR66734.1 - 1.5 8.8 15.9 2.2 8.3 15.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ArsB PF02040.15 EMR66735.1 - 7.6e-06 25.5 23.0 5.1e-05 22.8 12.5 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 EMR66735.1 - 0.0011 18.2 14.1 0.0011 18.2 14.1 2.3 2 1 0 2 2 2 1 Citrate transporter DPM3 PF08285.11 EMR66735.1 - 0.0094 16.1 1.1 1.6 9.0 0.1 3.1 3 0 0 3 3 3 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) UPF0767 PF15990.5 EMR66735.1 - 0.011 15.9 0.0 0.039 14.1 0.0 1.9 1 0 0 1 1 1 0 UPF0767 family DUF1772 PF08592.11 EMR66735.1 - 0.05 13.9 0.0 0.05 13.9 0.0 3.8 2 2 1 4 4 4 0 Domain of unknown function (DUF1772) GCP_C_terminal PF04130.13 EMR66736.1 - 1.2e-98 330.4 0.1 1.7e-98 329.9 0.1 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EMR66736.1 - 5.6e-57 193.7 0.6 1.8e-56 192.0 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Ribosomal_60s PF00428.19 EMR66736.1 - 0.033 14.8 0.5 2.3 8.9 0.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein APG17 PF04108.12 EMR66736.1 - 0.035 13.2 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 SAGA-Tad1 PF12767.7 EMR66737.1 - 6e-32 111.3 0.0 8e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Peptidase_S8 PF00082.22 EMR66738.1 - 1.2e-28 100.2 5.0 3.4e-28 98.8 5.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR66738.1 - 5e-12 46.3 0.0 8.6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 EarP PF10093.9 EMR66738.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP EMP24_GP25L PF01105.24 EMR66740.1 - 3e-52 177.2 0.0 3.4e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HXXSHH PF07586.11 EMR66740.1 - 0.13 11.8 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF3328 PF11807.8 EMR66741.1 - 3.5e-28 98.9 2.1 3.9e-28 98.7 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HET PF06985.11 EMR66742.1 - 2.7e-25 89.4 0.0 4.8e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 EMR66743.1 - 4.1e-21 75.9 0.8 2.3e-18 67.0 0.1 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EMR66743.1 - 1.7e-10 41.3 0.0 4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR66743.1 - 3e-09 36.3 0.0 3.6e-05 23.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EMR66743.1 - 4.7e-09 36.6 0.0 6.2e-06 26.7 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EMR66743.1 - 1.1e-08 35.1 0.0 2.2e-05 24.7 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EMR66743.1 - 1.4e-06 28.4 0.1 4.3e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF620 PF04788.12 EMR66743.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF620) DNA_methylase PF00145.17 EMR66744.1 - 7.8e-14 51.8 0.7 2.3e-05 23.9 0.0 3.7 3 1 0 3 3 3 2 C-5 cytosine-specific DNA methylase SNF2_N PF00176.23 EMR66744.1 - 2.1e-10 39.9 0.0 1.8e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain HC2 PF07382.11 EMR66744.1 - 2.5e-05 24.5 17.1 6.2e-05 23.2 17.1 1.6 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 PIEZO PF15917.5 EMR66744.1 - 0.16 11.4 5.0 15 5.0 5.5 2.5 2 0 0 2 2 2 0 Piezo Mod_r PF07200.13 EMR66744.1 - 0.92 9.6 5.8 3.4 7.8 4.1 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Peptidase_M43 PF05572.13 EMR66745.1 - 2.7e-08 33.8 0.1 4.2e-08 33.2 0.1 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EMR66745.1 - 0.00036 20.7 0.0 0.00056 20.1 0.0 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 EMR66745.1 - 0.0061 15.5 0.6 0.0091 15.0 0.6 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 EMR66745.1 - 0.014 16.0 0.7 0.016 15.8 0.7 1.3 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EMR66745.1 - 0.034 14.0 0.2 0.05 13.5 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EMR66745.1 - 0.043 13.5 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CorA PF01544.18 EMR66747.1 - 3.2e-08 33.3 0.1 5.3e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DnaJ PF00226.31 EMR66748.1 - 1.3e-17 63.7 0.3 2.7e-17 62.6 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain UL42 PF17638.2 EMR66748.1 - 0.043 13.8 0.1 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 HCMV UL42 ABC1 PF03109.16 EMR66749.1 - 9.8e-33 112.8 0.0 1.6e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Asn_synthase PF00733.21 EMR66750.1 - 2.2e-94 317.1 0.1 2.3e-55 188.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EMR66750.1 - 5.6e-36 123.2 0.0 8.8e-36 122.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EMR66750.1 - 3.7e-28 98.4 0.0 8.3e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EMR66750.1 - 8e-06 25.5 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EMR66750.1 - 0.0013 17.9 0.0 0.0029 16.8 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Snf7 PF03357.21 EMR66751.1 - 2.1e-28 99.1 22.5 2.1e-28 99.1 22.5 2.0 1 1 1 2 2 2 1 Snf7 Allexi_40kDa PF05549.11 EMR66751.1 - 0.083 12.4 8.6 0.14 11.6 8.6 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein Macro_2 PF14519.6 EMR66751.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Macro-like domain CAF1-p150_N PF15557.6 EMR66751.1 - 0.26 11.2 7.8 0.054 13.4 1.5 2.1 1 1 0 2 2 2 0 CAF1 complex subunit p150, region binding to PCNA SCAB_CC PF16712.5 EMR66751.1 - 0.91 9.3 15.0 0.04 13.7 3.6 2.2 1 1 1 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein DUF3138 PF11336.8 EMR66751.1 - 0.99 7.9 8.9 0.2 10.2 4.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Baculo_F PF12259.8 EMR66751.1 - 9.8 4.6 9.5 34 2.8 9.5 1.7 1 1 0 1 1 1 0 Baculovirus F protein Glyco_hydro_79C PF16862.5 EMR66752.1 - 3.5e-19 69.6 0.8 8.1e-19 68.4 0.8 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Cellulase PF00150.18 EMR66752.1 - 0.0046 16.4 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 EMR66753.1 - 7.5e-28 97.6 0.0 9.6e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR66753.1 - 1.2e-14 54.3 0.0 1.5e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR66753.1 - 5.7e-07 28.6 0.0 8e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase NACHT_N PF17100.5 EMR66754.1 - 3.8e-45 154.4 0.1 9.9e-45 153.1 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 EMR66754.1 - 4.1e-10 39.8 0.0 1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMR66754.1 - 4.1e-07 30.5 0.1 1.2e-06 29.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMR66754.1 - 3e-05 24.3 0.0 9.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EMR66754.1 - 0.0044 16.3 0.2 0.44 9.7 0.6 2.3 1 1 1 2 2 2 1 KAP family P-loop domain EcKinase PF02958.20 EMR66754.1 - 0.0093 15.3 0.9 0.17 11.2 0.0 2.6 3 0 0 3 3 3 1 Ecdysteroid kinase GIT1_C PF12205.8 EMR66754.1 - 0.012 15.7 1.1 0.039 14.1 0.1 2.2 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term TcpS PF17456.2 EMR66754.1 - 0.032 14.3 1.1 5.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S AAA_18 PF13238.6 EMR66754.1 - 0.097 13.2 0.0 0.33 11.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Porin_3 PF01459.22 EMR66755.1 - 1.9e-68 230.8 8.9 2.2e-68 230.7 8.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pex19 PF04614.12 EMR66756.1 - 3.1e-71 240.0 18.0 3.1e-71 240.0 18.0 1.8 2 0 0 2 2 2 1 Pex19 protein family PP2C_C PF07830.13 EMR66756.1 - 0.035 14.6 6.2 2.4 8.7 0.0 3.9 4 1 1 5 5 5 0 Protein serine/threonine phosphatase 2C, C-terminal domain GlutR_dimer PF00745.20 EMR66756.1 - 0.069 13.6 2.9 0.2 12.1 0.4 2.6 2 2 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Zn_clus PF00172.18 EMR66758.1 - 2.3e-08 34.0 8.3 3.6e-08 33.4 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Collagen PF01391.18 EMR66759.1 - 5.5e-05 22.9 16.9 5.5e-05 22.9 16.9 5.2 4 1 1 5 5 5 3 Collagen triple helix repeat (20 copies) Glyco_hydro_31 PF01055.26 EMR66760.1 - 1.6e-155 518.6 0.7 2e-155 518.3 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EMR66760.1 - 5.7e-39 132.9 0.0 1e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EMR66760.1 - 3.3e-13 49.7 2.1 9.6e-13 48.3 0.5 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like Ribosomal_L7Ae PF01248.26 EMR66761.1 - 1.5e-18 66.3 0.2 1.5e-18 66.3 0.2 2.3 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4050 PF13259.6 EMR66761.1 - 0.26 11.6 4.8 0.39 11.0 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) CDC45 PF02724.14 EMR66761.1 - 8 4.6 8.5 12 4.1 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1761 PF08570.10 EMR66762.1 - 2.7e-24 85.8 2.9 3.1e-24 85.6 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) DUF1413 PF07205.11 EMR66763.1 - 0.076 13.0 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) MFS_1 PF07690.16 EMR66766.1 - 9.9e-38 129.9 39.4 9.9e-38 129.9 39.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR66766.1 - 2.4e-10 39.9 13.0 2.4e-10 39.9 13.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter CDP-OH_P_transf PF01066.21 EMR66768.1 - 3.5e-17 62.9 0.1 3.5e-17 62.9 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FixP_N PF14715.6 EMR66768.1 - 2.8 7.8 7.1 8 6.3 1.3 2.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF1690 PF07956.11 EMR66769.1 - 1.2e-42 145.6 5.9 1.4e-42 145.4 5.9 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) SieB PF14163.6 EMR66769.1 - 0.047 13.2 1.1 0.066 12.7 1.1 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B Med9 PF07544.13 EMR66769.1 - 0.48 10.6 4.8 0.22 11.6 1.0 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LST1 PF05083.13 EMR66769.1 - 0.89 9.9 5.2 4.1 7.8 1.0 2.5 2 0 0 2 2 2 0 LST-1 protein Lzipper-MIP1 PF14389.6 EMR66769.1 - 1.5 9.2 10.9 1.3 9.4 4.0 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FUSC PF04632.12 EMR66769.1 - 3.4 6.1 6.1 3.5 6.1 6.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family SSF PF00474.17 EMR66770.1 - 1.2e-07 31.0 32.4 1.2e-06 27.7 32.4 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family Ycf70 PF17382.2 EMR66770.1 - 0.034 14.5 0.7 0.22 11.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized Ycf70-like RRM_1 PF00076.22 EMR66771.1 - 8.6e-24 83.1 0.0 3.1e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EMR66771.1 - 0.0025 17.8 0.0 0.044 13.9 0.0 2.7 2 1 0 2 2 2 1 Limkain b1 RRM_7 PF16367.5 EMR66771.1 - 0.096 12.8 0.1 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif TYW3 PF02676.14 EMR66772.1 - 8e-73 244.3 0.0 1.2e-72 243.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2014 PF09427.10 EMR66773.1 - 1.2e-114 382.1 5.1 1.7e-114 381.6 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) NDT80_PhoG PF05224.12 EMR66774.1 - 4.9e-33 114.9 0.0 1.1e-32 113.8 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.21 EMR66775.1 - 1.7e-61 208.3 0.0 2.4e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 EMR66775.1 - 0.0012 19.1 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR66775.1 - 0.031 14.2 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR66775.1 - 0.19 12.2 0.0 0.49 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_1 PF01979.20 EMR66776.1 - 2.4e-12 46.8 0.0 6.4e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR66776.1 - 4.1e-08 33.1 0.1 6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family SSB PF00436.25 EMR66777.1 - 1.2e-19 70.3 0.0 1.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family ADH_zinc_N PF00107.26 EMR66778.1 - 1.4e-08 34.8 0.0 7.5e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR66778.1 - 6.1e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMR66778.1 - 0.00031 21.8 0.0 0.00053 21.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding_2 PF13380.6 EMR66778.1 - 0.12 12.9 0.1 0.37 11.3 0.1 1.8 1 1 0 1 1 1 0 CoA binding domain EF-hand_6 PF13405.6 EMR66779.1 - 1.4e-10 40.2 0.0 0.00013 21.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EMR66779.1 - 2.5e-09 36.0 0.4 0.00027 20.3 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EMR66779.1 - 3.9e-06 27.2 0.0 1.6e-05 25.2 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EMR66779.1 - 1.4e-05 24.3 2.6 0.0083 15.6 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EMR66779.1 - 0.00013 21.7 0.0 0.41 10.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EMR66779.1 - 0.13 12.7 0.0 2.3 8.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Sugar_tr PF00083.24 EMR66782.1 - 1.3e-58 199.0 4.0 1.3e-58 199.0 4.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Ribosomal_L14 PF00238.19 EMR66783.1 - 1.2e-45 154.5 3.3 1.5e-45 154.3 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Glyco_hydro_28 PF00295.17 EMR66784.1 - 3.9e-36 124.7 4.6 7e-36 123.9 4.6 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EMR66784.1 - 1.7 8.5 18.2 1.4e+02 2.1 15.2 3.7 1 1 1 2 2 2 0 Pectate lyase superfamily protein Beta_helix PF13229.6 EMR66784.1 - 4.3 7.2 20.5 2.2 8.1 16.6 2.3 1 1 1 2 2 2 0 Right handed beta helix region Actin PF00022.19 EMR66785.1 - 9.3e-29 100.2 0.0 8.6e-20 70.7 0.0 2.6 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 EMR66785.1 - 0.00069 18.9 0.2 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 EMR66785.1 - 0.01 16.2 0.0 0.042 14.3 0.0 2.1 1 1 0 1 1 1 0 Cell division protein FtsA MreB_Mbl PF06723.13 EMR66785.1 - 0.019 13.8 0.0 0.091 11.6 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein MFS_1 PF07690.16 EMR66786.1 - 9.7e-26 90.5 29.0 1.6e-25 89.8 20.4 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily OMP_b-brl PF13505.6 EMR66787.1 - 0.032 14.4 0.9 0.05 13.7 0.6 1.4 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain RTA1 PF04479.13 EMR66788.1 - 3.5e-74 248.9 3.8 4.5e-74 248.5 3.8 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3593 PF12159.8 EMR66788.1 - 1.3 9.1 5.4 5.9 7.0 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) DHHC PF01529.20 EMR66788.1 - 1.5 8.9 5.7 2.3 8.3 0.1 3.0 2 1 0 2 2 2 0 DHHC palmitoyltransferase RTA1 PF04479.13 EMR66789.1 - 1.2e-57 194.9 1.6 1.2e-57 194.9 1.6 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF1097 PF06496.11 EMR66789.1 - 0.0015 18.6 3.2 0.0015 18.6 3.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1097) Fungal_trans PF04082.18 EMR66790.1 - 1.3e-19 70.3 0.0 2.6e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PRP1_N PF06424.12 EMR66790.1 - 0.018 15.4 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal SOG2 PF10428.9 EMR66790.1 - 0.64 9.1 2.9 0.23 10.6 0.4 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein Sugar_tr PF00083.24 EMR66791.1 - 8.3e-110 367.7 24.4 9.5e-110 367.5 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66791.1 - 6.5e-28 97.7 27.6 7.3e-21 74.5 5.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR66791.1 - 8.1e-05 21.4 23.5 0.0012 17.5 5.5 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EMR66791.1 - 0.00047 18.7 1.5 0.00047 18.7 1.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Catalase PF00199.19 EMR66792.1 - 2e-173 576.9 1.0 2.5e-173 576.6 1.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EMR66792.1 - 2e-19 69.5 0.1 3.6e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EMR66792.1 - 6.2e-13 48.7 0.1 1.5e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EMR66792.1 - 2.8e-11 43.5 0.0 5.8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family TPP_enzyme_N PF02776.18 EMR66793.1 - 1.6e-38 132.0 1.1 2.6e-38 131.3 0.6 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMR66793.1 - 3.6e-15 56.1 0.0 6.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMR66793.1 - 4.1e-08 33.1 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Alk_phosphatase PF00245.20 EMR66794.1 - 1.6e-77 261.2 0.0 2e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EMR66794.1 - 0.042 13.2 0.2 0.066 12.6 0.2 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily AAA_3 PF07726.11 EMR66794.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4451 PF14616.6 EMR66795.1 - 2.4e-18 66.5 0.0 4.7e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Acetyltransf_3 PF13302.7 EMR66796.1 - 5.1e-31 108.2 0.0 6.6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMR66796.1 - 0.014 15.1 0.0 0.52 10.0 0.0 2.2 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR66796.1 - 0.063 13.5 0.1 1 9.6 0.1 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Skp1 PF01466.19 EMR66797.1 - 1.6e-29 101.7 0.4 3.4e-29 100.7 0.4 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EMR66797.1 - 3.8e-24 84.6 0.3 8.8e-24 83.5 0.2 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF615 PF04751.14 EMR66797.1 - 0.36 10.8 2.5 17 5.4 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF615) GMC_oxred_N PF00732.19 EMR66798.1 - 7.8e-62 209.3 0.0 1e-61 208.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR66798.1 - 3.6e-30 105.4 0.0 6.5e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMR66798.1 - 0.00059 19.0 0.2 0.00086 18.5 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EMR66798.1 - 0.0097 15.2 0.2 0.018 14.3 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EMR66798.1 - 0.033 13.3 0.9 4.6 6.2 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain Sugar_tr PF00083.24 EMR66799.1 - 3.3e-27 95.5 3.5 1.5e-12 47.2 0.0 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EMR66799.1 - 4.8e-09 35.6 23.9 1.7e-07 30.5 12.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinocilin PF15033.6 EMR66799.1 - 0.0059 16.2 0.1 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Kinocilin protein SNF2_N PF00176.23 EMR66800.1 - 1.7e-43 148.7 0.1 3.2e-43 147.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR66800.1 - 1.8e-24 86.2 0.0 6.5e-22 78.0 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR66800.1 - 1.7e-08 34.6 0.6 7.7e-08 32.5 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMR66800.1 - 0.00036 19.8 1.1 0.00061 19.1 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Prominin PF05478.11 EMR66800.1 - 0.3 9.0 0.5 0.48 8.3 0.5 1.2 1 0 0 1 1 1 0 Prominin MFS_1 PF07690.16 EMR66801.1 - 1.4e-13 50.5 34.9 1.6e-07 30.6 13.5 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 EMR66801.1 - 0.00061 18.5 0.5 0.016 13.9 0.0 2.3 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like Claudin_2 PF13903.6 EMR66801.1 - 0.019 14.7 0.0 0.57 9.9 0.0 2.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.9 EMR66801.1 - 0.67 8.7 3.5 22 3.7 0.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 EMR66801.1 - 1.8 8.2 0.0 1.8 8.2 0.0 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4131) HeLo PF14479.6 EMR66803.1 - 3.7e-26 92.2 2.4 4.7e-26 91.9 2.4 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation GRP PF07172.11 EMR66805.1 - 3.4e-06 27.7 1.6 4.8e-06 27.2 1.6 1.3 1 0 0 1 1 1 1 Glycine rich protein family DUF429 PF04250.13 EMR66805.1 - 0.0058 16.4 0.4 0.0091 15.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF429) BAF1_ABF1 PF04684.13 EMR66805.1 - 0.08 12.0 0.1 0.094 11.8 0.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Chorion_3 PF05387.11 EMR66805.1 - 0.93 9.1 3.1 1.2 8.7 3.1 1.1 1 0 0 1 1 1 0 Chorion family 3 DUF2967 PF11179.8 EMR66805.1 - 2.1 6.3 5.9 2.4 6.1 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) K_channel_TID PF07941.11 EMR66805.1 - 6.7 7.3 26.9 4.2e+02 1.5 26.9 2.4 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain GSH_synth_ATP PF03917.17 EMR66806.1 - 4.8e-121 404.1 0.0 5.2e-120 400.6 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EMR66806.1 - 4.2e-33 113.9 0.0 6.7e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Serglycin PF04360.12 EMR66807.1 - 0.3 11.0 3.4 0.56 10.2 3.4 1.3 1 0 0 1 1 1 0 Serglycin GATase_5 PF13507.6 EMR66809.1 - 2.1e-98 328.6 0.0 3.1e-98 328.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EMR66809.1 - 2.8e-37 128.2 0.1 2.3e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EMR66809.1 - 5.3e-24 84.4 0.0 9.6e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EMR66809.1 - 5.9e-20 71.5 0.0 1.3e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Ral PF11058.8 EMR66810.1 - 0.095 12.3 0.3 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral SET PF00856.28 EMR66812.1 - 7e-08 33.0 0.0 2.1e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 SET domain Tmemb_55A PF09788.9 EMR66812.1 - 0.076 12.1 0.1 0.076 12.1 0.1 1.9 2 0 0 2 2 2 0 Transmembrane protein 55A Pyr_redox_2 PF07992.14 EMR66813.1 - 1.6e-05 24.3 0.0 4.3e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Arf PF00025.21 EMR66814.1 - 7.2e-59 198.1 0.2 2e-57 193.4 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMR66814.1 - 8.2e-10 38.9 0.1 1.1e-09 38.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EMR66814.1 - 3.1e-08 33.2 0.1 6.4e-08 32.1 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 EMR66814.1 - 6.2e-07 29.1 0.0 8.3e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EMR66814.1 - 1.6e-06 27.6 0.0 2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMR66814.1 - 1.9e-05 24.1 0.0 2.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EMR66814.1 - 0.0046 16.5 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMR66814.1 - 0.065 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PTCB-BRCT PF12738.7 EMR66815.1 - 8e-34 115.4 0.0 6.7e-19 67.6 0.0 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 EMR66815.1 - 3.3e-25 88.2 0.0 2.8e-11 43.6 0.0 4.7 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EMR66815.1 - 4.8e-17 62.1 0.0 1.1e-05 25.7 0.0 4.0 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EMR66815.1 - 8.9e-05 22.7 0.0 2.8 8.3 0.0 4.1 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EMR66815.1 - 0.0031 17.6 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain HalX PF08663.10 EMR66816.1 - 0.09 13.1 1.5 0.22 11.8 0.1 2.2 2 1 0 2 2 2 0 HalX domain CybS PF05328.12 EMR66816.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit HSBP1 PF06825.12 EMR66816.1 - 0.12 12.2 2.0 3.1 7.7 0.1 2.7 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF1996 PF09362.10 EMR66817.1 - 2e-77 260.3 3.7 2e-77 260.3 3.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) WD40 PF00400.32 EMR66818.1 - 0.0023 18.7 0.0 0.0069 17.2 0.0 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat CN_hydrolase PF00795.22 EMR66820.1 - 4.5e-44 150.7 0.0 5.3e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPR_1 PF00515.28 EMR66821.1 - 5.4e-35 117.8 8.0 3.9e-08 32.8 0.1 8.2 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 EMR66821.1 - 3.7e-30 101.6 10.1 6.2e-06 25.9 0.0 8.4 6 1 2 8 8 8 5 Tetratricopeptide repeat DnaJ PF00226.31 EMR66821.1 - 3.3e-27 94.4 6.1 6.1e-27 93.5 4.6 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 EMR66821.1 - 1.9e-20 72.2 9.8 0.0001 21.9 0.0 7.5 5 3 2 7 7 7 4 TPR repeat TPR_19 PF14559.6 EMR66821.1 - 4e-20 72.1 8.8 3.2e-09 37.2 0.0 5.6 4 2 1 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EMR66821.1 - 5.5e-20 69.8 1.4 0.00041 20.3 0.1 6.5 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EMR66821.1 - 2.2e-17 63.4 7.1 2.7e-05 24.7 0.0 5.9 4 3 2 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR66821.1 - 2.4e-14 53.3 5.3 6.2e-05 23.1 0.1 4.4 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EMR66821.1 - 1.2e-13 50.6 13.8 0.00027 21.5 0.0 7.5 6 2 2 8 8 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMR66821.1 - 2.5e-13 50.1 13.2 0.00058 20.1 0.2 7.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EMR66821.1 - 3.9e-12 46.1 9.1 0.014 15.5 1.0 5.3 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 EMR66821.1 - 3.4e-10 39.9 4.6 0.082 13.6 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMR66821.1 - 3.8e-10 39.4 14.9 0.076 13.4 0.0 7.5 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMR66821.1 - 2.1e-09 36.8 1.9 0.064 13.3 0.0 6.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EMR66821.1 - 2.5e-07 30.2 8.1 0.037 13.2 0.0 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMR66821.1 - 8.4e-06 25.8 3.9 3.4 7.8 0.0 4.6 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EMR66821.1 - 1.9e-05 24.4 11.9 0.32 10.9 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 EMR66821.1 - 0.00043 20.6 0.6 7.4 7.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 EMR66821.1 - 0.00049 20.6 13.3 0.057 13.8 0.1 4.7 3 1 2 5 5 5 1 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 EMR66821.1 - 0.0013 19.2 0.7 0.49 10.9 0.0 3.5 2 1 2 4 4 4 1 Alkyl sulfatase dimerisation TPR_21 PF09976.9 EMR66821.1 - 0.0025 17.6 6.8 1.7 8.3 0.1 4.0 2 1 1 4 4 4 2 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 EMR66821.1 - 0.0068 15.8 0.1 2.7 7.3 0.0 3.2 3 0 0 3 3 3 1 Coatomer epsilon subunit TPR_20 PF14561.6 EMR66821.1 - 0.019 15.3 11.2 1.1 9.6 0.0 4.8 3 3 2 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 EMR66821.1 - 0.022 14.8 0.7 34 4.5 0.0 4.8 4 2 1 5 5 5 0 Domain of Unknown Function (DUF3856) SRP_TPR_like PF17004.5 EMR66821.1 - 0.42 10.6 3.2 2.4 8.2 0.3 3.3 1 1 3 4 4 4 0 Putative TPR-like repeat MAS20 PF02064.15 EMR66821.1 - 4.9 7.3 5.6 12 6.1 0.0 3.0 3 1 1 4 4 3 0 MAS20 protein import receptor DUF4203 PF13886.6 EMR66823.1 - 4.6e-46 157.0 27.1 6.1e-46 156.6 27.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Aldedh PF00171.22 EMR66824.1 - 4.9e-118 394.6 0.3 1.4e-83 280.9 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.16 EMR66825.1 - 1.3e-13 50.7 15.6 1.3e-13 50.7 15.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR66825.1 - 7.4e-11 41.6 8.7 1.3e-10 40.8 8.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Sulfotransfer_4 PF17784.1 EMR66826.1 - 2.2e-55 187.8 0.0 2.6e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR66826.1 - 0.0017 18.8 0.0 0.014 15.8 0.0 2.2 2 1 1 3 3 3 1 Sulfotransferase family Zn_clus PF00172.18 EMR66827.1 - 0.015 15.4 0.3 0.028 14.5 0.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SesA PF17107.5 EMR66828.1 - 0.081 13.1 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases adh_short PF00106.25 EMR66829.1 - 2.3e-09 37.0 0.0 7.2e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66829.1 - 0.00025 20.7 0.0 0.0096 15.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66829.1 - 0.0058 16.6 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR66829.1 - 0.04 13.4 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 EMR66830.1 - 5.8e-44 150.6 0.0 7.2e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mpv17_PMP22 PF04117.12 EMR66831.1 - 9.7e-18 64.2 0.1 2e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family SURF4 PF02077.15 EMR66833.1 - 5.7e-97 324.5 6.1 6.4e-97 324.3 6.1 1.0 1 0 0 1 1 1 1 SURF4 family GMC_oxred_N PF00732.19 EMR66835.1 - 9.4e-48 163.1 0.0 1.4e-47 162.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR66835.1 - 7.5e-42 143.2 0.0 1.4e-41 142.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR66835.1 - 4.9e-06 25.9 0.2 0.0022 17.1 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EMR66835.1 - 8.3e-05 22.3 0.1 0.00025 20.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR66835.1 - 0.00069 18.8 1.2 0.00081 18.5 0.2 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EMR66835.1 - 0.0013 18.0 0.3 0.0025 17.1 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR66835.1 - 0.0035 16.7 0.1 0.057 12.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR66835.1 - 0.015 14.2 0.5 0.025 13.4 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 EMR66835.1 - 0.019 15.2 1.4 0.053 13.8 1.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EMR66835.1 - 0.056 12.7 0.1 2 7.6 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EMR66835.1 - 0.061 13.3 0.4 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sugar_tr PF00083.24 EMR66836.1 - 7e-82 275.7 14.5 8e-82 275.5 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR66836.1 - 3.9e-30 105.0 18.1 5.2e-30 104.6 18.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR66836.1 - 3.4e-06 25.8 2.9 0.00026 19.6 0.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMR66836.1 - 0.012 14.0 1.0 0.012 14.0 1.0 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 EMR66837.1 - 1.4e-06 28.3 9.7 3.1e-06 27.2 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CxC4 PF18717.1 EMR66837.1 - 0.009 15.9 0.0 0.009 15.9 0.0 2.0 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases DUF2335 PF10097.9 EMR66837.1 - 0.74 9.8 3.5 1.4 8.9 0.4 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) Bul1_C PF04426.12 EMR66838.1 - 0.00017 21.1 0.0 0.00063 19.3 0.0 1.8 2 0 0 2 2 2 1 Bul1 C terminus Bul1_N PF04425.12 EMR66838.1 - 0.003 16.4 0.2 0.03 13.1 0.0 2.5 1 1 2 3 3 3 1 Bul1 N terminus Arrestin_N PF00339.29 EMR66838.1 - 0.074 13.1 0.3 0.91 9.6 0.1 2.7 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Eryth_link_C PF16915.5 EMR66838.1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Annelid erythrocruorin linker subunit C-terminus ABC2_membrane PF01061.24 EMR66839.1 - 2.8e-84 281.8 53.7 1.1e-42 145.8 25.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EMR66839.1 - 1.4e-33 116.3 0.4 2e-15 57.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EMR66839.1 - 2e-31 107.7 1.1 4.5e-25 87.4 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EMR66839.1 - 4e-15 56.2 0.3 1.2e-14 54.6 0.3 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EMR66839.1 - 3.1e-07 30.9 0.1 0.00019 21.9 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EMR66839.1 - 9.1e-06 25.7 0.0 0.0077 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EMR66839.1 - 1.3e-05 24.5 29.1 0.00022 20.5 9.3 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 EMR66839.1 - 1.6e-05 25.4 0.0 0.0017 18.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMR66839.1 - 3e-05 24.0 0.1 0.00049 20.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 EMR66839.1 - 4.5e-05 23.7 0.3 0.006 16.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 EMR66839.1 - 0.00013 21.7 0.3 0.46 10.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EMR66839.1 - 0.0004 20.4 0.2 0.072 13.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EMR66839.1 - 0.00046 20.4 0.0 0.042 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EMR66839.1 - 0.00055 19.6 0.1 0.019 14.6 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EMR66839.1 - 0.0007 19.1 0.5 0.064 12.7 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMR66839.1 - 0.0025 18.1 0.1 0.33 11.2 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMR66839.1 - 0.0049 16.5 0.0 0.73 9.4 0.1 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMR66839.1 - 0.013 15.5 0.2 0.37 10.7 0.3 2.4 2 0 0 2 2 2 0 NACHT domain INCENP_ARK-bind PF03941.15 EMR66839.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region AAA_24 PF13479.6 EMR66839.1 - 0.024 14.4 0.2 0.37 10.5 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EMR66839.1 - 0.042 13.6 0.6 3.5 7.3 0.5 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EMR66839.1 - 0.064 12.6 0.5 8.7 5.6 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 EMR66839.1 - 0.065 12.4 0.2 1.9 7.6 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 EMR66839.1 - 0.097 13.1 0.9 2.2 8.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 EMR66839.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase HisKA_4TM PF16926.5 EMR66839.1 - 0.14 11.7 1.1 0.58 9.7 0.1 2.2 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase KAP_NTPase PF07693.14 EMR66839.1 - 0.16 11.2 0.0 0.92 8.7 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain Septin PF00735.18 EMR66839.1 - 0.19 10.9 0.6 0.6 9.3 0.2 1.9 2 0 0 2 2 2 0 Septin Clat_adaptor_s PF01217.20 EMR66840.1 - 3.8e-15 56.1 1.4 2.4e-14 53.4 1.4 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.18 EMR66841.1 - 4.4e-54 182.7 0.0 7.2e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EMR66841.1 - 1.5e-31 109.8 0.0 2.3e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding MCM PF00493.23 EMR66842.1 - 4e-101 336.8 0.0 5.6e-101 336.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EMR66842.1 - 7.6e-28 96.8 3.6 1.9e-27 95.5 3.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EMR66842.1 - 3.2e-19 69.0 0.1 5.5e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 EMR66842.1 - 4.2e-07 30.0 0.0 2.8e-06 27.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMR66842.1 - 2.4e-06 27.1 0.0 0.00026 20.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EMR66842.1 - 0.00023 21.0 0.0 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMR66842.1 - 0.019 14.7 0.2 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain PWI PF01480.17 EMR66843.1 - 6.2e-32 109.7 0.0 1.2e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 PWI domain IBR PF01485.21 EMR66844.1 - 3.4e-08 33.6 36.4 1.9e-06 28.0 11.5 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain COG4 PF08318.12 EMR66845.1 - 4.7e-99 331.6 0.0 1.8e-72 244.2 0.0 2.6 1 1 1 2 2 2 2 COG4 transport protein Glyco_hydro_2_C PF02836.17 EMR66846.1 - 1e-12 47.8 0.1 5.3e-11 42.2 0.0 2.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EMR66846.1 - 5.8e-10 39.8 0.0 1.9e-09 38.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EMR66846.1 - 9.3e-06 25.6 0.0 3.6e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Abhydrolase_3 PF07859.13 EMR66847.1 - 1.9e-13 50.8 0.0 2.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Zip PF02535.22 EMR66848.1 - 2.1e-58 198.1 6.9 5.5e-58 196.8 6.9 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2157 PF09925.9 EMR66848.1 - 0.061 13.1 1.4 0.41 10.4 0.1 2.9 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) FAA_hydrolase PF01557.18 EMR66849.1 - 1.9e-51 174.9 0.0 2.2e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ZU5 PF00791.20 EMR66849.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 ZU5 domain TBCA PF02970.16 EMR66850.1 - 4.7e-24 84.5 5.1 6.4e-24 84.1 5.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A Upf2 PF04050.14 EMR66850.1 - 0.0085 16.8 2.0 0.011 16.5 2.0 1.2 1 0 0 1 1 1 1 Up-frameshift suppressor 2 TMF_DNA_bd PF12329.8 EMR66850.1 - 2.2 8.3 13.3 5.5 7.1 9.9 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ISG65-75 PF11727.8 EMR66850.1 - 4 6.6 9.8 5.3 6.2 5.7 2.0 1 1 0 2 2 2 0 Invariant surface glycoprotein PTR2 PF00854.21 EMR66851.1 - 6.1e-78 262.4 6.5 8e-78 262.0 6.5 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EMR66851.1 - 1.6e-05 24.0 28.6 0.00021 20.3 4.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily 7TM_GPCR_Sra PF02117.16 EMR66851.1 - 5 5.9 5.8 3 6.6 0.1 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sra Glyco_hydro_18 PF00704.28 EMR66852.1 - 3.5e-85 286.5 5.8 4.3e-85 286.2 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 COX17 PF05051.13 EMR66853.1 - 2.7e-21 75.7 5.8 3.3e-21 75.4 5.8 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Alg6_Alg8 PF03155.15 EMR66854.1 - 1.7e-128 429.7 29.3 1.1e-80 272.0 12.7 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DDE_1 PF03184.19 EMR66856.1 - 2.2e-16 60.0 0.0 1.6e-15 57.2 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_psq PF05225.16 EMR66856.1 - 4.9e-07 29.4 0.1 1e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EMR66856.1 - 0.00055 19.9 0.5 0.0015 18.5 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CUE PF02845.16 EMR66857.1 - 2.6e-11 43.0 0.0 4.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3446 PF11928.8 EMR66857.1 - 0.029 14.7 6.1 0.045 14.1 5.2 1.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Ashwin PF15323.6 EMR66857.1 - 0.16 12.0 6.1 0.23 11.5 6.1 1.1 1 0 0 1 1 1 0 Developmental protein G2BR PF18442.1 EMR66857.1 - 0.3 10.8 11.2 0.73 9.5 11.2 1.6 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 EMR66857.1 - 0.3 11.2 0.9 0.63 10.1 0.9 1.4 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 TMEM171 PF15471.6 EMR66857.1 - 0.57 9.1 3.2 0.96 8.4 3.2 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Conotoxin PF02950.17 EMR66857.1 - 1.1 10.4 2.9 2.5 9.2 0.0 2.6 2 1 0 2 2 2 0 Conotoxin FAM177 PF14774.6 EMR66858.1 - 0.028 14.8 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 FAM177 family DEAD PF00270.29 EMR66859.1 - 3.6e-42 144.1 0.0 9.8e-42 142.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR66859.1 - 5.4e-24 84.7 0.0 1.3e-22 80.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR66859.1 - 0.0001 22.4 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMR66859.1 - 0.25 10.5 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase FAD_binding_4 PF01565.23 EMR66860.1 - 6e-16 58.4 2.3 6e-16 58.4 2.3 1.9 2 0 0 2 2 2 1 FAD binding domain DUF4160 PF13711.6 EMR66860.1 - 0.051 13.9 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Thi4 PF01946.17 EMR66860.1 - 0.059 12.6 1.1 0.17 11.1 0.9 1.9 2 0 0 2 2 2 0 Thi4 family WD40 PF00400.32 EMR66861.1 - 4.6e-12 46.3 3.3 0.017 16.0 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR66861.1 - 6.9e-05 23.1 0.1 0.15 12.4 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SMC_N PF02463.19 EMR66862.1 - 2.7e-35 121.8 12.9 2.7e-35 121.8 12.9 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMR66862.1 - 6.4e-20 71.6 5.3 6.5e-20 71.6 0.1 3.4 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EMR66862.1 - 7.2e-11 43.0 15.6 7.2e-11 43.0 15.6 6.4 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 EMR66862.1 - 9.4e-05 22.1 0.1 0.00022 20.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EMR66862.1 - 0.00015 21.7 0.2 0.00015 21.7 0.2 2.5 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Tup_N PF08581.10 EMR66862.1 - 0.0025 18.1 2.6 0.0025 18.1 2.6 7.7 7 2 1 8 8 8 1 Tup N-terminal DUF4250 PF14056.6 EMR66862.1 - 0.011 15.7 4.4 8.4 6.4 0.0 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4250) HIP1_clath_bdg PF16515.5 EMR66862.1 - 0.015 15.9 7.7 0.015 15.9 7.7 8.5 4 2 4 8 8 8 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HSBP1 PF06825.12 EMR66862.1 - 2 8.3 8.5 0.22 11.4 0.2 3.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 HALZ PF02183.18 EMR66862.1 - 5.5 7.3 26.0 1.5 9.1 1.1 5.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper GFA PF04828.14 EMR66863.1 - 1.3e-14 54.3 4.4 4.7e-07 30.0 0.0 3.1 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.13 EMR66863.1 - 0.14 11.9 3.7 2.3 8.0 1.4 2.5 2 0 0 2 2 2 0 CSL zinc finger Nudix_N_2 PF14803.6 EMR66863.1 - 0.2 11.6 10.1 4.6 7.3 0.0 4.1 4 0 0 4 4 4 0 Nudix N-terminal 4HBT_2 PF13279.6 EMR66864.1 - 4.3e-05 24.0 0.0 5.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Tyrosinase PF00264.20 EMR66865.1 - 8.7e-37 127.6 0.0 1.5e-36 126.8 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Thioredoxin PF00085.20 EMR66866.1 - 2.3e-60 201.0 0.0 7.6e-30 102.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EMR66866.1 - 8.5e-25 87.5 1.7 8.5e-25 87.5 1.7 2.7 3 0 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EMR66866.1 - 3.7e-17 62.8 0.0 1.9e-08 34.7 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EMR66866.1 - 2.4e-13 50.1 0.0 8.6e-06 25.3 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EMR66866.1 - 1.2e-09 38.2 0.1 0.00072 19.5 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 EMR66866.1 - 1.2e-09 38.4 0.0 0.00061 20.1 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EMR66866.1 - 7.1e-09 35.7 0.0 0.0025 18.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 EMR66866.1 - 8e-06 25.6 0.3 0.014 15.1 0.0 2.3 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.13 EMR66866.1 - 1e-05 25.7 0.7 5.8e-05 23.2 0.0 2.5 3 1 0 3 3 3 1 ERp29, N-terminal domain HyaE PF07449.11 EMR66866.1 - 1.7e-05 24.7 0.0 0.011 15.7 0.0 2.8 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 EMR66866.1 - 6.3e-05 22.9 0.0 0.22 11.6 0.0 2.7 3 0 0 3 3 2 2 Thioredoxin domain Thioredoxin_9 PF14595.6 EMR66866.1 - 0.00029 20.6 0.0 0.14 11.9 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin TraF PF13728.6 EMR66866.1 - 0.00036 20.4 0.0 0.079 12.8 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 EMR66866.1 - 0.0014 18.8 0.2 3.4 8.0 0.0 3.1 2 1 0 2 2 2 2 Glutaredoxin Thioredoxin_4 PF13462.6 EMR66866.1 - 0.0023 18.1 4.6 2.9 8.0 0.1 4.0 3 2 2 5 5 5 2 Thioredoxin DSBA PF01323.20 EMR66866.1 - 0.0056 16.5 3.4 6.3 6.5 0.9 3.3 2 1 1 3 3 3 2 DSBA-like thioredoxin domain LAT PF15234.6 EMR66866.1 - 0.02 14.7 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Linker for activation of T-cells GTP_EFTU PF00009.27 EMR66867.1 - 3.4e-57 193.1 0.2 4.5e-57 192.7 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMR66867.1 - 9.3e-26 90.3 0.0 2.5e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMR66867.1 - 1.1e-16 61.0 2.3 1.1e-16 61.0 2.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMR66867.1 - 1.3e-05 25.2 0.1 2.8e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR66867.1 - 0.0012 18.7 0.1 0.0031 17.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EMR66867.1 - 0.019 14.6 0.3 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EMR66867.1 - 0.067 12.9 0.2 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EMR66867.1 - 0.19 11.1 0.1 0.72 9.2 0.1 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.21 EMR66868.1 - 6.1e-13 48.3 2.5 8.5e-13 47.9 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 EMR66868.1 - 0.022 14.6 0.2 0.027 14.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) ATP_transf PF09830.9 EMR66870.1 - 6.1e-24 84.0 0.1 1e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 EMR66870.1 - 0.01 15.6 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) HIT PF01230.23 EMR66870.1 - 0.026 15.2 0.2 0.047 14.4 0.2 1.4 1 0 0 1 1 1 0 HIT domain Neurochondrin PF05536.11 EMR66871.1 - 2.4e-76 257.4 0.0 3.1e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Neurochondrin Sec7_N PF12783.7 EMR66871.1 - 0.057 13.3 0.6 0.22 11.4 0.3 2.1 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UPF0181 PF03701.14 EMR66871.1 - 0.15 11.7 0.2 0.7 9.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) NUFIP2 PF15293.6 EMR66873.1 - 0.028 13.3 0.4 0.043 12.7 0.4 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 DNA_pol_A PF00476.20 EMR66874.1 - 1e-55 189.3 0.0 1.7e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNApol_Exo PF18136.1 EMR66874.1 - 3.4e-20 72.3 0.0 5.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain FliT PF05400.13 EMR66874.1 - 0.11 13.4 0.1 0.35 11.7 0.1 1.8 1 0 0 1 1 1 0 Flagellar protein FliT DUF3405 PF11885.8 EMR66875.1 - 4.1e-176 586.6 0.7 3.9e-139 464.6 0.1 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) PRKCSH PF07915.13 EMR66876.1 - 2.1e-18 67.1 0.8 4e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EMR66876.1 - 0.00063 19.5 0.0 0.28 10.8 0.1 2.3 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein DUF4834 PF16118.5 EMR66876.1 - 0.47 11.4 4.5 0.75 10.8 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 EMR66876.1 - 6.1 6.4 8.6 1.5 8.4 5.1 1.8 2 0 0 2 2 2 0 Spt20 family MFS_1 PF07690.16 EMR66878.1 - 6.2e-06 25.4 21.1 0.012 14.6 22.2 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR66878.1 - 8e-06 24.6 2.7 8e-06 24.6 2.7 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF2964 PF11177.8 EMR66878.1 - 0.15 12.3 0.4 0.15 12.3 0.4 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2964) Cu-oxidase_2 PF07731.14 EMR66879.1 - 8.9e-40 135.6 0.5 2.5e-39 134.1 0.2 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EMR66879.1 - 5.3e-31 107.9 0.0 1e-30 107.0 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase TFIID-18kDa PF02269.16 EMR66880.1 - 5e-17 61.7 0.0 8.1e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EMR66880.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EMR66880.1 - 0.055 13.7 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 EMR66880.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 EMR66880.1 - 0.084 13.0 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Tcp11 PF05794.13 EMR66881.1 - 7.5e-90 302.1 0.5 1.9e-89 300.8 0.5 1.5 1 1 0 1 1 1 1 T-complex protein 11 p450 PF00067.22 EMR66882.1 - 2.4e-59 201.3 0.0 3.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tfb4 PF03850.14 EMR66883.1 - 1.1e-89 300.7 0.0 1.4e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Actin PF00022.19 EMR66884.1 - 1e-85 287.8 0.0 1.7e-52 178.5 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 EMR66884.1 - 0.049 12.5 0.1 2.9 6.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 EMR66885.1 - 9.9e-44 149.6 4.6 7.7e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Glyco_hydro_88 PF07470.13 EMR66887.1 - 2.5e-67 227.4 14.1 3.3e-67 227.0 14.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 adh_short PF00106.25 EMR66888.1 - 1.2e-09 37.9 0.1 1.6e-06 27.7 0.0 3.8 3 1 1 4 4 4 1 short chain dehydrogenase KR PF08659.10 EMR66888.1 - 0.00018 21.5 0.0 0.063 13.2 0.0 2.5 2 0 0 2 2 2 2 KR domain TraC PF07820.12 EMR66888.1 - 0.099 13.0 0.9 0.18 12.2 0.3 1.7 2 0 0 2 2 2 0 TraC-like protein Spt20 PF12090.8 EMR66888.1 - 0.65 9.6 9.0 1 8.9 9.0 1.2 1 0 0 1 1 1 0 Spt20 family TPR_12 PF13424.6 EMR66889.1 - 7.6e-22 77.4 11.9 2.6e-10 40.4 0.8 6.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 EMR66889.1 - 4.6e-10 39.0 22.7 0.011 15.6 2.1 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.22 EMR66889.1 - 1.1e-08 34.6 0.0 0.0004 19.6 0.0 2.2 1 1 1 2 2 2 2 NB-ARC domain TPR_7 PF13176.6 EMR66889.1 - 8e-08 31.8 8.3 0.1 12.6 0.2 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EMR66889.1 - 4.1e-07 29.7 3.2 0.006 16.0 1.1 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 EMR66889.1 - 3.1e-06 27.3 2.8 0.45 11.3 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMR66889.1 - 3.5e-06 26.8 13.7 0.68 10.3 0.0 5.6 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMR66889.1 - 1.2e-05 24.9 13.0 0.0016 18.2 1.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMR66889.1 - 1.2e-05 25.7 10.5 0.76 10.8 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMR66889.1 - 0.00022 21.4 0.5 17 6.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMR66889.1 - 0.00025 20.9 11.6 6.6 7.1 1.3 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR66889.1 - 0.001 19.5 6.7 0.35 11.4 0.1 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat PPR PF01535.20 EMR66889.1 - 0.004 17.3 0.1 0.48 10.8 0.0 3.3 3 0 0 3 3 3 1 PPR repeat TPR_16 PF13432.6 EMR66889.1 - 0.018 15.7 13.2 3.2 8.5 0.3 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat RepC PF06504.11 EMR66889.1 - 0.029 13.6 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Replication protein C (RepC) SNAP PF14938.6 EMR66889.1 - 0.036 13.5 1.4 0.84 9.0 0.6 2.4 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP DrsE PF02635.15 EMR66889.1 - 0.057 13.8 0.2 16 5.9 0.1 2.5 2 0 0 2 2 2 0 DsrE/DsrF-like family TPR_6 PF13174.6 EMR66889.1 - 0.21 12.3 7.5 72 4.4 0.8 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DHHC PF01529.20 EMR66892.1 - 6.1e-35 120.2 11.9 6.1e-35 120.2 11.9 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EMR66892.1 - 1e-26 93.3 0.0 3.3e-12 46.8 0.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR66892.1 - 4.4e-25 87.7 1.4 2.1e-07 31.3 0.0 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR66892.1 - 3.6e-23 81.3 0.0 8.9e-07 29.1 0.0 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EMR66892.1 - 6.2e-23 80.2 0.0 1.5e-05 25.2 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EMR66892.1 - 5.5e-22 75.5 0.5 7.3e-07 29.0 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Polysacc_synt_C PF14667.6 EMR66892.1 - 0.15 12.1 7.3 0.41 10.7 7.3 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain GtrA PF04138.14 EMR66892.1 - 0.37 11.0 8.4 0.18 12.0 4.9 2.3 2 0 0 2 2 2 0 GtrA-like protein BLOC1_2 PF10046.9 EMR66895.1 - 0.0043 17.3 0.6 0.013 15.8 0.0 2.0 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 eIF3_p135 PF12807.7 EMR66895.1 - 0.028 14.5 0.0 0.077 13.0 0.0 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 Prominin PF05478.11 EMR66895.1 - 0.036 12.0 1.2 0.045 11.7 1.2 1.1 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.12 EMR66895.1 - 0.038 14.5 3.9 0.072 13.6 0.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EMR66895.1 - 0.055 13.5 0.8 0.42 10.7 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Nuc_recep-AF1 PF11825.8 EMR66895.1 - 0.086 12.9 0.4 0.15 12.1 0.4 1.4 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 LPP PF04728.13 EMR66895.1 - 0.17 12.3 5.3 0.27 11.6 0.2 3.4 3 1 2 5 5 5 0 Lipoprotein leucine-zipper DUF948 PF06103.11 EMR66895.1 - 0.39 11.0 6.0 0.21 11.9 0.5 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ERCC4 PF02732.15 EMR66897.1 - 5.4e-28 98.2 0.0 5.4e-28 98.2 0.0 1.6 2 0 0 2 2 1 1 ERCC4 domain Uso1_p115_C PF04871.13 EMR66897.1 - 0.12 12.7 18.6 0.21 11.9 18.6 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cellulose_synt PF03552.14 EMR66897.1 - 0.23 9.9 4.7 0.31 9.5 4.7 1.1 1 0 0 1 1 1 0 Cellulose synthase GNT-I PF03071.15 EMR66897.1 - 0.25 10.1 2.8 0.37 9.5 2.8 1.3 1 0 0 1 1 1 0 GNT-I family CENP-I PF07778.11 EMR66897.1 - 0.45 9.2 5.8 0.75 8.4 5.8 1.3 1 0 0 1 1 1 0 Mis6 Ndc1_Nup PF09531.10 EMR66897.1 - 0.58 8.8 5.0 0.82 8.3 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 EMR66897.1 - 0.65 9.1 2.2 0.93 8.6 2.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 EMR66897.1 - 0.84 8.4 11.6 1.4 7.6 11.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SOBP PF15279.6 EMR66897.1 - 0.87 10.1 7.5 0.15 12.7 4.0 1.5 2 0 0 2 2 2 0 Sine oculis-binding protein Presenilin PF01080.17 EMR66897.1 - 0.92 8.2 9.3 0.037 12.8 3.8 1.4 2 0 0 2 2 2 0 Presenilin PA26 PF04636.13 EMR66897.1 - 1.4 7.8 7.2 2 7.2 7.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GREB1 PF15782.5 EMR66897.1 - 1.9 5.5 7.5 2.7 5.0 7.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5102 PF17104.5 EMR66897.1 - 2.3 8.2 15.6 0.7 9.9 11.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) RR_TM4-6 PF06459.12 EMR66897.1 - 3.2 7.5 15.0 5.4 6.8 15.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Chorion_2 PF03964.15 EMR66897.1 - 3.3 8.6 8.1 18 6.2 0.8 2.4 2 0 0 2 2 2 0 Chorion family 2 SR-25 PF10500.9 EMR66897.1 - 3.5 7.2 32.4 0.36 10.4 23.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Endostatin PF06482.11 EMR66897.1 - 3.6 6.9 10.7 28 4.1 0.0 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Tho2 PF11262.8 EMR66897.1 - 5.3 6.2 13.4 8.3 5.5 13.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RNA_pol_Rpc4 PF05132.14 EMR66897.1 - 7.8 6.9 11.3 16 5.9 10.2 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4129 PF13559.6 EMR66898.1 - 0.047 13.9 2.5 0.11 12.8 0.6 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4129) FAD_binding_4 PF01565.23 EMR66899.1 - 2.9e-27 95.1 0.4 8.7e-27 93.6 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EMR66899.1 - 0.013 15.6 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like GAF PF01590.26 EMR66899.1 - 0.064 13.9 0.0 0.21 12.2 0.0 1.9 3 0 0 3 3 3 0 GAF domain Sugar_tr PF00083.24 EMR66900.1 - 7.9e-34 117.3 24.1 7.5e-18 64.6 8.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR66900.1 - 4e-24 85.2 41.3 3e-14 52.7 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR66900.1 - 6.2e-05 21.7 20.8 0.01 14.4 6.0 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein DUF2231 PF09990.9 EMR66900.1 - 0.58 10.6 7.2 1.7 9.1 5.5 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Peptidase_M24 PF00557.24 EMR66901.1 - 1.3e-40 139.4 0.0 6.2e-26 91.4 0.1 2.3 2 0 0 2 2 2 2 Metallopeptidase family M24 Creatinase_N PF01321.18 EMR66901.1 - 0.00055 20.6 0.0 0.00099 19.8 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain His_Phos_1 PF00300.22 EMR66902.1 - 2.9e-20 72.8 0.0 4.9e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CDT1_C PF16679.5 EMR66902.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain CP12 PF02672.15 EMR66903.1 - 0.96 10.2 5.9 0.22 12.3 0.9 2.1 2 1 0 2 2 2 0 CP12 domain BNIP2 PF12496.8 EMR66903.1 - 2.3 8.6 7.0 2.3 8.7 2.0 2.0 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RXT2_N PF08595.11 EMR66903.1 - 2.8 7.9 7.5 8.4 6.4 0.9 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.6 EMR66903.1 - 5.6 7.4 9.7 11 6.4 1.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYDLN_acid PF09538.10 EMR66903.1 - 9.6 6.9 11.5 1.4 9.7 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAD_binding_2 PF00890.24 EMR66904.1 - 5.8e-61 206.8 6.7 6.9e-61 206.6 6.7 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR66904.1 - 2.6e-09 37.1 4.1 6.2e-09 35.9 3.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR66904.1 - 9.9e-08 32.1 1.2 2.9e-07 30.6 1.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR66904.1 - 2.8e-07 30.3 1.8 4.4e-07 29.6 1.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR66904.1 - 4.7e-07 29.3 2.2 1e-06 28.2 1.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR66904.1 - 5.2e-06 26.9 0.2 0.0046 17.5 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR66904.1 - 6.5e-05 22.3 0.1 8.2e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EMR66904.1 - 0.0001 21.6 0.9 0.0001 21.6 0.9 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 EMR66904.1 - 0.0002 20.7 1.6 0.00033 20.0 0.6 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EMR66904.1 - 0.0007 18.4 0.5 0.0007 18.4 0.5 2.6 3 1 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EMR66904.1 - 0.00092 18.6 0.2 0.0024 17.2 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EMR66904.1 - 0.018 14.1 0.1 0.055 12.5 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EMR66904.1 - 0.031 13.5 0.1 0.31 10.3 0.2 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EMR66904.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EMR66904.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 EMR66904.1 - 0.26 10.0 0.1 0.36 9.6 0.1 1.1 1 0 0 1 1 1 0 MCRA family Thi4 PF01946.17 EMR66906.1 - 8.1e-114 378.7 0.1 9.6e-114 378.5 0.1 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EMR66906.1 - 9.3e-09 35.3 2.3 1.6e-07 31.3 0.9 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR66906.1 - 5.8e-06 26.4 0.4 1.6e-05 25.0 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR66906.1 - 1.9e-05 23.9 0.2 4.4e-05 22.7 0.2 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMR66906.1 - 0.00012 22.2 0.2 0.00034 20.6 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EMR66906.1 - 0.00019 20.6 2.8 0.0049 16.0 0.3 2.9 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR66906.1 - 0.00024 20.5 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR66906.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR66906.1 - 0.079 12.3 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR66906.1 - 0.1 11.4 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 EMR66906.1 - 0.11 11.2 0.3 0.16 10.6 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EMR66906.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GSIII_N PF12437.8 EMR66907.1 - 0.16 11.6 0.4 0.54 9.9 0.0 1.9 2 0 0 2 2 2 0 Glutamine synthetase type III N terminal DUF4603 PF15376.6 EMR66907.1 - 0.32 8.3 2.7 0.39 8.1 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) PARP PF00644.20 EMR66908.1 - 3.2e-09 36.6 0.5 5.8e-09 35.8 0.5 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 EMR66908.1 - 0.017 15.4 0.2 0.089 13.0 0.2 2.2 1 1 0 1 1 1 0 ARTD15 N-terminal domain Sod_Cu PF00080.20 EMR66909.1 - 7.4e-47 159.1 6.3 8.6e-47 158.9 6.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.17 EMR66911.1 - 1.5e-66 221.6 0.0 3.3e-21 75.8 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EMR66911.1 - 5.4e-25 87.8 0.0 2.1e-24 85.9 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 EMR66911.1 - 3.1e-06 26.6 0.0 9.7e-06 25.0 0.0 1.8 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) DUF3334 PF11813.8 EMR66911.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) HATPase_c_3 PF13589.6 EMR66912.1 - 1.4e-05 24.9 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DPBB_1 PF03330.18 EMR66913.1 - 9.7e-06 25.8 0.0 2e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EMR66913.1 - 0.013 15.3 0.2 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 Barwin family RsgI_N PF12791.7 EMR66913.1 - 0.041 13.8 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma factor N-terminus Robl_LC7 PF03259.17 EMR66914.1 - 2e-07 30.7 0.2 4.6e-06 26.3 0.1 2.1 2 0 0 2 2 2 1 Roadblock/LC7 domain CFIA_Pcf11 PF11526.8 EMR66914.1 - 0.047 14.2 13.3 0.098 13.2 13.3 1.6 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 NPR3 PF03666.13 EMR66914.1 - 0.25 10.1 1.5 0.27 10.0 1.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 EMR66914.1 - 0.29 9.6 6.7 0.28 9.7 6.7 1.1 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 EMR66914.1 - 0.62 8.3 10.5 0.71 8.2 10.5 1.1 1 0 0 1 1 1 0 Menin NST1 PF13945.6 EMR66914.1 - 3.1 7.9 11.9 4.5 7.3 11.9 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator AMP-binding PF00501.28 EMR66916.1 - 8.1e-68 228.9 0.3 1.6e-67 227.9 0.3 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR66916.1 - 1.5e-05 25.9 0.0 3.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DEAD PF00270.29 EMR66917.1 - 6e-39 133.6 0.0 1e-38 132.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR66917.1 - 1.2e-25 90.0 0.2 2.8e-24 85.6 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR66917.1 - 1.9e-08 34.5 0.0 4.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EMR66917.1 - 0.00027 20.6 0.0 0.00035 20.2 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 EMR66917.1 - 0.049 13.0 0.1 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 EMR66917.1 - 0.15 12.6 0.8 0.34 11.5 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) DEAD PF00270.29 EMR66918.1 - 6.8e-41 139.9 0.0 1e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR66918.1 - 5.7e-26 91.0 0.2 2.1e-25 89.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EMR66918.1 - 0.00066 18.5 0.0 0.00099 17.9 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain UTP25 PF06862.12 EMR66918.1 - 0.14 10.9 0.1 5 5.8 0.0 2.7 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Mg_trans_NIPA PF05653.14 EMR66919.1 - 0.0014 17.8 2.9 0.0018 17.5 2.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA HPHLAWLY PF14925.6 EMR66919.1 - 0.025 13.3 1.6 0.041 12.6 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function Metallophos PF00149.28 EMR66921.1 - 1.4e-12 48.5 0.0 3e-07 31.2 0.0 2.2 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMR66921.1 - 2.7e-05 24.4 0.0 0.0063 16.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain RP-C_C PF11800.8 EMR66921.1 - 0.0048 17.0 0.1 0.0074 16.4 0.1 1.2 1 0 0 1 1 1 1 Replication protein C C-terminal region BAF1_ABF1 PF04684.13 EMR66921.1 - 0.019 14.1 0.5 0.024 13.7 0.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor THOC2_N PF16134.5 EMR66921.1 - 0.026 13.2 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus ECH_1 PF00378.20 EMR66922.1 - 2.1e-62 210.7 0.1 2.8e-62 210.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMR66922.1 - 2.1e-29 103.1 1.3 1.5e-25 90.5 0.6 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EMR66922.1 - 0.0097 15.9 0.0 0.042 13.8 0.0 1.9 1 1 1 2 2 2 1 Peptidase family S49 Myc_N PF01056.18 EMR66923.1 - 0.18 11.6 4.0 0.29 11.0 4.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region PGA2 PF07543.12 EMR66923.1 - 5.7 6.9 13.2 16 5.4 13.2 1.8 1 1 0 1 1 1 0 Protein trafficking PGA2 Ndc1_Nup PF09531.10 EMR66923.1 - 5.9 5.5 5.0 8.2 5.0 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FYDLN_acid PF09538.10 EMR66923.1 - 8.8 7.1 12.1 16 6.3 7.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PPP4R2 PF09184.11 EMR66923.1 - 9.2 5.8 11.6 16 5.0 11.6 1.4 1 0 0 1 1 1 0 PPP4R2 Aminotran_1_2 PF00155.21 EMR66924.1 - 1e-19 70.9 0.0 6.3e-16 58.5 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class I and II CorA PF01544.18 EMR66925.1 - 3.1e-16 59.6 0.3 4.5e-16 59.0 0.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 EMR66925.1 - 0.024 14.4 0.2 0.034 13.8 0.2 1.2 1 0 0 1 1 1 0 Transposase Fzo_mitofusin PF04799.13 EMR66925.1 - 0.18 11.3 2.0 0.81 9.2 0.2 2.2 2 0 0 2 2 2 0 fzo-like conserved region Glyco_tran_WbsX PF14307.6 EMR66926.1 - 9.6e-36 123.9 0.3 1.7e-23 83.7 0.0 2.1 1 1 0 2 2 2 2 Glycosyltransferase WbsX vATP-synt_E PF01991.18 EMR66927.1 - 8.1e-63 211.4 1.4 9.4e-63 211.2 1.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Ipi1_N PF12333.8 EMR66928.1 - 1e-25 90.3 0.0 1.7e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation CNH PF00780.22 EMR66929.1 - 1.2e-62 212.0 0.0 2e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EMR66929.1 - 1.9e-29 103.2 0.7 3.2e-29 102.5 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EMR66929.1 - 8.4e-07 29.2 0.0 5.1e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Tropomyosin PF00261.20 EMR66929.1 - 0.0066 15.8 1.3 0.014 14.8 1.3 1.5 1 0 0 1 1 1 1 Tropomyosin SQS_PSY PF00494.19 EMR66930.1 - 2.8e-56 191.0 0.5 3.6e-56 190.6 0.5 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase 4HBT PF03061.22 EMR66931.1 - 2e-06 28.1 0.2 1e-05 25.8 0.1 2.1 2 0 0 2 2 2 1 Thioesterase superfamily Rrp44_CSD1 PF17216.3 EMR66931.1 - 0.13 12.0 1.1 0.21 11.3 1.1 1.3 1 0 0 1 1 1 0 Rrp44-like cold shock domain Pex14_N PF04695.13 EMR66931.1 - 0.59 10.8 7.8 0.071 13.8 2.6 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSase_L_D2 PF02786.17 EMR66932.1 - 4.2e-113 376.0 0.3 4e-84 281.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EMR66932.1 - 1e-47 161.1 0.0 2.9e-47 159.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EMR66932.1 - 1.9e-46 158.2 0.0 6.2e-46 156.6 0.0 2.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EMR66932.1 - 8.9e-45 152.3 0.0 2e-44 151.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EMR66932.1 - 3.6e-38 130.6 0.0 8.2e-38 129.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EMR66932.1 - 1.7e-30 106.2 0.0 3.7e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EMR66932.1 - 6.4e-22 77.5 0.0 3.2e-21 75.3 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 EMR66932.1 - 8.9e-18 64.4 0.3 2.6e-09 36.9 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EMR66932.1 - 8.9e-16 58.0 1.0 4.5e-07 29.6 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EMR66932.1 - 2.4e-10 40.2 0.0 4.9e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DJ-1_PfpI PF01965.24 EMR66932.1 - 1.2e-05 25.2 0.2 0.014 15.2 0.0 4.3 4 0 0 4 4 4 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 EMR66932.1 - 1.4e-05 24.9 1.4 0.00054 19.8 0.4 2.7 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 EMR66932.1 - 3.2e-05 24.0 0.4 0.11 12.6 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EMR66932.1 - 0.0013 18.5 0.1 1.7 8.4 0.0 3.0 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Aminotran_1_2 PF00155.21 EMR66933.1 - 2.1e-58 198.2 0.0 2.5e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EMR66933.1 - 0.06 12.2 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Allinase Spc24 PF08286.11 EMR66934.1 - 7.6e-42 141.8 0.5 2.4e-38 130.6 0.0 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 Nsp1_C PF05064.13 EMR66934.1 - 0.0013 18.5 3.3 0.049 13.4 0.3 2.2 2 0 0 2 2 2 2 Nsp1-like C-terminal region Prefoldin_2 PF01920.20 EMR66934.1 - 0.0082 16.1 5.2 0.48 10.4 0.2 2.4 2 1 0 2 2 2 2 Prefoldin subunit V_ATPase_I PF01496.19 EMR66934.1 - 0.023 12.7 0.5 0.022 12.7 0.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BAR_3 PF16746.5 EMR66934.1 - 0.049 13.3 4.3 0.31 10.7 1.3 2.0 1 1 1 2 2 2 0 BAR domain of APPL family Vps5 PF09325.10 EMR66934.1 - 0.053 13.1 4.7 0.079 12.5 4.7 1.3 1 0 0 1 1 1 0 Vps5 C terminal like CLZ PF16526.5 EMR66934.1 - 0.059 13.7 5.6 0.67 10.3 0.4 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 EMR66934.1 - 0.16 12.5 10.1 0.25 11.9 10.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 EMR66934.1 - 0.21 12.0 3.4 0.87 10.0 0.2 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 EMR66934.1 - 0.3 11.4 5.1 0.52 10.6 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) GvpG PF05120.12 EMR66934.1 - 0.33 11.0 3.3 0.88 9.6 3.3 1.6 1 0 0 1 1 1 0 Gas vesicle protein G FUSC PF04632.12 EMR66934.1 - 1.8 7.0 4.1 1.9 6.9 4.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family NTPase_I-T PF01931.18 EMR66936.1 - 0.0043 16.9 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF84 Med9 PF07544.13 EMR66936.1 - 0.045 13.9 1.6 8.4 6.6 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1929 PF09118.11 EMR66938.1 - 1.4e-25 89.4 1.3 3.5e-25 88.1 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 EMR66938.1 - 1.3e-20 73.8 2.8 1.4e-20 73.6 1.3 1.9 2 0 0 2 2 2 1 F5/8 type C domain Kelch_6 PF13964.6 EMR66938.1 - 8.6e-16 57.6 2.4 9.9e-06 25.7 0.0 4.6 3 1 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 EMR66938.1 - 2.5e-10 39.7 2.3 0.0008 18.9 0.5 4.4 4 1 0 4 4 4 2 Kelch motif Glyoxal_oxid_N PF07250.11 EMR66938.1 - 2.6e-09 36.6 0.2 5.4e-05 22.5 0.2 2.8 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 EMR66938.1 - 2.1e-05 24.3 0.1 1.1 9.4 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 EMR66938.1 - 3.2e-05 23.8 13.8 0.00044 20.2 0.2 5.8 6 1 0 6 6 6 1 Galactose oxidase, central domain DPBB_1 PF03330.18 EMR66938.1 - 0.0056 16.9 0.0 0.02 15.2 0.0 1.9 1 0 0 1 1 1 1 Lytic transglycolase Kelch_3 PF13415.6 EMR66938.1 - 0.051 13.9 6.9 4.2 7.8 0.0 5.1 5 0 0 5 5 5 0 Galactose oxidase, central domain Secretin PF00263.21 EMR66938.1 - 0.2 11.3 1.1 24 4.5 0.1 3.3 3 0 0 3 3 3 0 Bacterial type II and III secretion system protein RabGAP-TBC PF00566.18 EMR66939.1 - 4.8e-47 160.4 0.1 1.4e-46 158.9 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Macoilin PF09726.9 EMR66940.1 - 1.8 7.0 5.5 2.3 6.7 5.5 1.2 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 EMR66940.1 - 1.9 7.8 21.0 4.3 6.7 21.0 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 EMR66940.1 - 2.7 7.1 5.9 4.8 6.3 5.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SHR3_chaperone PF08229.11 EMR66941.1 - 8.4e-77 256.4 0.0 1e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2157 PF09925.9 EMR66941.1 - 0.51 10.1 3.3 8.1 6.2 0.7 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) DUF5453 PF17534.2 EMR66941.1 - 0.9 9.5 5.7 0.27 11.2 1.9 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5453) Pyridox_oxase_2 PF12766.7 EMR66942.1 - 1.3e-20 73.9 0.0 2.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DNA_topoisoIV PF00521.20 EMR66943.1 - 9.3e-112 374.0 5.0 9.3e-112 374.0 5.0 2.8 2 2 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EMR66943.1 - 5e-49 165.8 3.6 2.6e-48 163.5 3.6 2.4 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EMR66943.1 - 1.3e-24 86.6 2.6 2.9e-24 85.5 2.6 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EMR66943.1 - 4.8e-13 49.6 0.0 2e-12 47.6 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EMR66943.1 - 1.2e-06 28.7 0.1 5.9e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Toprim domain Glyco_hydro_76 PF03663.14 EMR66944.1 - 3.3e-124 415.1 13.1 3.8e-124 414.9 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Reticulon PF02453.17 EMR66945.1 - 1.6e-33 115.9 3.6 2.7e-33 115.1 3.6 1.4 1 0 0 1 1 1 1 Reticulon FUSC_2 PF13515.6 EMR66945.1 - 0.047 13.8 6.0 1.1 9.4 1.0 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like ApoO PF09769.9 EMR66945.1 - 0.43 10.6 3.8 4.3 7.3 0.1 2.5 3 0 0 3 3 3 0 Apolipoprotein O TatD_DNase PF01026.21 EMR66946.1 - 2.9e-31 108.8 0.0 4.9e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Trypan_PARP PF05887.11 EMR66946.1 - 0.00032 20.7 2.7 0.00049 20.1 1.2 2.1 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) TPR_1 PF00515.28 EMR66948.1 - 1.8e-06 27.5 1.8 0.22 11.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR66948.1 - 0.00024 21.0 6.4 0.44 10.8 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMR66948.1 - 0.017 15.6 0.6 0.087 13.4 0.9 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMR66948.1 - 0.044 14.0 0.2 0.28 11.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SAPIS-gp6 PF16722.5 EMR66948.1 - 0.68 10.4 2.9 0.78 10.2 1.3 1.9 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus TPR_7 PF13176.6 EMR66948.1 - 1.8 8.8 6.3 17 5.7 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 EMR66949.1 - 8.1e-05 23.3 3.1 1 10.3 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR66949.1 - 0.076 13.3 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_11 PF17123.5 EMR66950.1 - 7.1e-05 22.5 3.9 9.5e-05 22.1 0.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EMR66950.1 - 0.005 17.1 2.5 0.017 15.5 0.3 2.2 2 0 0 2 2 2 1 Ring finger domain RAP1 PF07218.11 EMR66951.1 - 8.8 4.5 8.1 14 3.8 8.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Fis1_TPR_C PF14853.6 EMR66952.1 - 5.6e-24 84.0 1.8 9.4e-24 83.2 1.8 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EMR66952.1 - 4.5e-18 64.6 0.0 7.4e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EMR66952.1 - 0.019 15.0 2.7 0.042 14.0 2.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_43 PF04616.14 EMR66953.1 - 2.4e-27 96.0 0.3 3e-27 95.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Mcp5_PH PF12814.7 EMR66954.1 - 2.2e-44 150.5 0.1 6e-44 149.1 0.1 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EMR66954.1 - 9.2e-06 26.1 0.0 3.2e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 PH domain Glyco_hydro_61 PF03443.14 EMR66955.1 - 9.9e-56 188.9 0.1 1.2e-55 188.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 EMR66957.1 - 9.2e-23 80.7 46.6 9.2e-23 80.7 46.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily zf-CCCH PF00642.24 EMR66958.1 - 2e-08 33.9 2.5 3.9e-08 33.0 2.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EMR66958.1 - 5.5e-07 29.3 4.2 9.5e-07 28.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMR66958.1 - 1.5e-06 27.9 7.0 2.9e-06 27.0 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR66958.1 - 2.1e-06 27.6 5.9 4.2e-06 26.7 5.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMR66958.1 - 7.7e-06 25.7 7.4 1.4e-05 24.8 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMR66958.1 - 9.9e-06 25.4 6.8 1.7e-05 24.7 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 EMR66958.1 - 2e-05 24.5 6.2 4e-05 23.5 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 EMR66958.1 - 2.8e-05 24.2 2.8 2.8e-05 24.2 2.8 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 EMR66958.1 - 0.00011 22.5 5.9 0.0002 21.6 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 EMR66958.1 - 0.00012 21.8 2.6 0.00022 20.9 2.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EMR66958.1 - 0.0017 18.5 7.9 0.0039 17.3 7.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EMR66958.1 - 0.004 17.0 5.0 0.0075 16.1 5.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 EMR66958.1 - 0.09 13.3 3.6 0.2 12.2 3.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 EMR66958.1 - 0.092 13.1 2.6 0.19 12.1 2.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain adh_short PF00106.25 EMR66959.1 - 1.3e-43 148.7 0.5 2.7e-43 147.7 0.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR66959.1 - 2.2e-42 145.2 0.5 5.5e-42 143.9 0.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR66959.1 - 6.5e-10 39.2 1.5 7.9e-10 38.9 0.2 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 EMR66959.1 - 9.8e-05 22.4 0.2 0.00067 19.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 EMR66959.1 - 0.0012 18.8 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 EMR66959.1 - 0.0067 15.9 0.2 0.033 13.6 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMR66959.1 - 0.024 13.8 0.2 0.039 13.1 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMR66959.1 - 0.03 13.8 0.2 0.087 12.3 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Snf7 PF03357.21 EMR66961.1 - 1.2e-05 25.0 27.6 1.2e-05 25.0 27.6 1.6 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 EMR66961.1 - 0.0057 16.6 9.1 0.014 15.4 9.1 1.6 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Rh5 PF18515.1 EMR66961.1 - 0.023 14.0 2.6 0.03 13.6 2.6 1.1 1 0 0 1 1 1 0 Rh5 coiled-coil domain HD PF01966.22 EMR66962.1 - 1.7e-05 25.1 0.3 3.2e-05 24.1 0.3 1.5 1 0 0 1 1 1 1 HD domain Peptidase_C12 PF01088.21 EMR66963.1 - 5.8e-56 189.6 0.0 6.5e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Fungal_trans PF04082.18 EMR66964.1 - 4.3e-12 45.6 0.0 9.7e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spt20 PF12090.8 EMR66964.1 - 0.00092 18.9 2.8 0.0016 18.1 2.8 1.4 1 0 0 1 1 1 1 Spt20 family NINJA_B PF16136.5 EMR66964.1 - 0.033 14.6 1.5 0.079 13.3 1.5 1.6 1 0 0 1 1 1 0 Putative nuclear localisation signal Roughex PF06020.11 EMR66964.1 - 1.4 7.9 4.2 2.8 7.0 4.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein NADH-u_ox-rdase PF10785.9 EMR66965.1 - 4.7e-30 104.1 0.3 1e-29 103.0 0.3 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EMR66965.1 - 5e-26 90.5 0.0 7.2e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Curlin_rpt PF07012.12 EMR66966.1 - 3.5 7.7 12.1 10 6.2 1.2 3.3 1 1 2 3 3 3 0 Curlin associated repeat bZIP_2 PF07716.15 EMR66967.1 - 9.2e-08 32.1 13.3 1.9e-07 31.1 13.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EMR66967.1 - 1.2e-07 31.7 18.7 1.9e-07 31.0 18.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EMR66967.1 - 0.0067 16.9 11.6 0.012 16.1 11.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF641 PF04859.12 EMR66967.1 - 0.12 12.7 5.0 0.19 12.0 5.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Pox_A11 PF05061.13 EMR66967.1 - 0.19 11.0 0.2 0.25 10.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein Cut12 PF11500.8 EMR66967.1 - 0.31 11.0 7.4 0.86 9.6 7.4 1.7 1 0 0 1 1 1 0 Spindle pole body formation-associated protein AAA_13 PF13166.6 EMR66967.1 - 0.41 9.2 2.1 0.55 8.8 2.1 1.1 1 0 0 1 1 1 0 AAA domain FUSC PF04632.12 EMR66967.1 - 6.7 5.1 5.2 10 4.5 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pex16 PF08610.10 EMR66968.1 - 6.8e-138 459.2 0.7 7.6e-138 459.1 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) BNR_2 PF13088.6 EMR66969.1 - 1.4e-14 54.0 0.1 1.1e-12 47.9 0.0 2.2 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EMR66969.1 - 0.00093 18.9 24.6 0.051 13.6 0.7 6.2 6 0 0 6 6 6 3 BNR/Asp-box repeat BNR_4 PF15892.5 EMR66969.1 - 0.014 14.8 1.0 0.028 13.8 1.0 1.5 1 1 0 1 1 1 0 BNR repeat-containing family member CHB_HEX_C PF03174.13 EMR66969.1 - 0.095 12.7 0.4 4.3 7.4 0.0 3.4 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain Swi3 PF07962.12 EMR66970.1 - 3.6e-31 107.0 0.5 6.6e-31 106.1 0.5 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Pectinesterase PF01095.19 EMR66971.1 - 5.6e-144 478.4 98.4 2.1e-45 154.8 5.8 7.2 8 0 0 8 8 8 5 Pectinesterase DSHCT PF08148.12 EMR66972.1 - 1.2e-51 174.6 0.7 2.5e-51 173.6 0.7 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EMR66972.1 - 2e-40 137.7 0.1 2.6e-39 134.1 0.1 2.5 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EMR66972.1 - 9.5e-24 84.8 0.0 2.3e-23 83.5 0.0 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EMR66972.1 - 2.7e-18 66.3 0.0 7.4e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR66972.1 - 5.8e-07 29.8 0.0 3.2e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR66972.1 - 7.3e-05 22.8 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Trypan_PARP PF05887.11 EMR66972.1 - 7.6 6.5 8.1 2.1 8.3 4.3 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cellulase PF00150.18 EMR66973.1 - 4.1e-19 69.1 4.6 6.3e-19 68.5 4.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Oxysterol_BP PF01237.18 EMR66974.1 - 6.8e-131 436.5 0.1 4.5e-130 433.8 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 EMR66974.1 - 2.7e-16 59.4 0.1 1.1e-08 35.2 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.29 EMR66974.1 - 9.9e-13 48.5 0.4 2.1e-12 47.5 0.4 1.6 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 EMR66974.1 - 1.6e-12 46.4 0.0 0.00083 19.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EMR66974.1 - 3e-12 46.4 0.2 0.0085 16.5 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EMR66974.1 - 3.4e-12 46.8 0.0 2.1e-07 31.4 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR66974.1 - 2.5e-09 37.5 0.1 1.2e-05 25.7 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.6 EMR66974.1 - 3.9e-08 33.5 0.9 1e-07 32.1 0.9 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EMR66974.1 - 2.9e-05 24.4 2.1 8.4e-05 23.0 2.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_17 PF18012.1 EMR66974.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF2796 PF10986.8 EMR66975.1 - 0.12 12.3 1.8 0.17 11.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) ACPS PF01648.20 EMR66976.1 - 8.5e-08 32.3 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DLH PF01738.18 EMR66977.1 - 1.4e-12 47.6 0.0 1.7e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EMR66977.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3297 PF11730.8 EMR66978.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Xpo1 PF08389.12 EMR66979.1 - 0.012 15.7 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Exportin 1-like protein 4HBT_3 PF13622.6 EMR66980.1 - 1.7e-80 270.9 2.4 2.1e-80 270.6 2.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMR66980.1 - 2e-23 82.7 0.0 4.5e-11 42.7 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Peptidase_M28 PF04389.17 EMR66981.1 - 7.5e-31 107.4 0.2 1.2e-30 106.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EMR66981.1 - 0.00024 20.9 2.6 0.0034 17.1 2.6 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DEP PF00610.21 EMR66981.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.7 1 1 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CdiI_2 PF18593.1 EMR66981.1 - 0.023 15.3 0.1 8.4 7.1 0.0 2.5 2 0 0 2 2 2 0 CdiI immunity protein DNA_pol_phi PF04931.13 EMR66981.1 - 0.079 11.1 0.1 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi BioT2 PF15368.6 EMR66981.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis family BioT2 ATP12 PF07542.11 EMR66982.1 - 4.8e-41 139.9 0.0 9.3e-41 138.9 0.0 1.5 2 0 0 2 2 2 1 ATP12 chaperone protein U3snoRNP10 PF12397.8 EMR66984.1 - 0.075 13.4 0.2 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Fer2 PF00111.27 EMR66985.1 - 7e-07 29.1 0.9 1.6e-06 27.9 0.9 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MOSC PF03473.17 EMR66985.1 - 2.9e-05 24.1 0.1 6e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 MOSC domain FAD_binding_6 PF00970.24 EMR66985.1 - 0.0006 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EMR66985.1 - 0.0007 20.2 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2_3 PF13085.6 EMR66985.1 - 0.16 12.0 0.4 0.43 10.6 0.4 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Peptidase_S49_N PF08496.10 EMR66986.1 - 0.24 11.4 3.4 0.74 9.9 3.4 1.8 1 1 0 1 1 1 0 Peptidase family S49 N-terminal GAGA_bind PF06217.12 EMR66986.1 - 2.8 8.1 6.9 0.93 9.7 4.1 1.6 2 0 0 2 2 2 0 GAGA binding protein-like family Stm1_N PF09598.10 EMR66986.1 - 9.3 7.2 10.0 2.3 9.1 6.0 2.1 2 0 0 2 2 2 0 Stm1 Metallophos PF00149.28 EMR66987.1 - 0.00011 22.8 0.3 0.00015 22.4 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1996 PF09362.10 EMR66988.1 - 3.9e-62 210.3 0.0 4.7e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Esterase_phd PF10503.9 EMR66990.1 - 4e-08 33.0 3.3 7.4e-08 32.2 3.2 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMR66990.1 - 2.6e-07 30.3 0.0 4.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EMR66990.1 - 0.00026 20.9 0.1 0.00047 20.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR66990.1 - 0.00047 19.5 0.1 0.083 12.1 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 EMR66990.1 - 0.0024 16.6 0.1 0.0037 16.0 0.1 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF1180 PF06679.12 EMR66990.1 - 2.7 8.4 4.3 1.5 9.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Nop14 PF04147.12 EMR66991.1 - 0.22 9.7 9.4 0.26 9.4 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 EMR66991.1 - 0.23 11.3 6.2 0.32 10.9 6.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 EMR66991.1 - 0.3 9.3 7.9 0.37 9.0 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein GCIP PF13324.6 EMR66991.1 - 0.62 9.6 4.9 0.97 9.0 4.9 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 EMR66991.1 - 0.65 8.0 21.4 0.85 7.6 21.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EMR66991.1 - 1.2 8.5 11.5 1.5 8.2 11.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EMR66991.1 - 5.6 6.2 10.1 7.6 5.8 10.1 1.2 1 0 0 1 1 1 0 BUD22 eIF-3c_N PF05470.12 EMR66991.1 - 8.8 4.5 6.1 11 4.1 6.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus ABC2_membrane_3 PF12698.7 EMR66992.1 - 0.86 8.6 13.2 1.7 7.7 13.2 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Septin PF00735.18 EMR66993.1 - 2e-112 375.1 0.6 2.4e-112 374.8 0.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EMR66993.1 - 8.2e-08 32.3 0.0 1.8e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMR66993.1 - 1.7e-05 24.5 1.2 0.043 13.3 0.1 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EMR66993.1 - 1.8e-05 24.2 0.0 3.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EMR66993.1 - 2.6e-05 24.2 0.1 0.00069 19.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EMR66993.1 - 0.0011 19.1 1.1 0.95 9.5 0.1 2.7 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.6 EMR66993.1 - 0.0027 18.1 0.0 0.012 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EMR66993.1 - 0.0072 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 EMR66993.1 - 0.0073 15.8 0.0 0.045 13.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EMR66993.1 - 0.0073 16.6 0.0 0.017 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMR66993.1 - 0.022 15.2 0.8 0.035 14.6 0.5 1.7 1 1 0 1 1 1 0 ABC transporter Microtub_bd PF16796.5 EMR66993.1 - 0.031 14.2 0.2 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 Microtubule binding FtsK_SpoIIIE PF01580.18 EMR66993.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 EMR66993.1 - 0.095 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EMR66993.1 - 0.2 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PAP2 PF01569.21 EMR66994.1 - 6.9e-16 58.3 5.1 6.9e-16 58.3 5.1 2.0 2 0 0 2 2 2 1 PAP2 superfamily CHD5 PF04420.14 EMR66994.1 - 0.29 11.0 1.1 0.69 9.8 1.1 1.6 1 0 0 1 1 1 0 CHD5-like protein PAP2_3 PF14378.6 EMR66994.1 - 3.5 7.3 16.0 0.065 12.9 1.7 2.8 3 0 0 3 3 3 0 PAP2 superfamily MFS_1 PF07690.16 EMR66995.1 - 3e-30 105.4 23.7 3.6e-30 105.1 23.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR66995.1 - 0.0024 16.8 4.2 0.0024 16.8 4.2 2.2 2 0 0 2 2 2 2 MFS_1 like family zf-MYND PF01753.18 EMR66996.1 - 3e-11 43.2 11.3 5.2e-11 42.5 11.3 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EMR66996.1 - 0.13 12.6 8.5 0.39 11.1 8.5 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 EMR66999.1 - 1.7e-33 116.0 11.7 2.5e-33 115.5 11.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.11 EMR66999.1 - 0.0035 17.1 0.2 0.0035 17.1 0.2 2.5 2 1 1 3 3 3 1 7TM receptor with intracellular HD hydrolase Macro PF01661.21 EMR67000.1 - 1.7e-23 82.9 0.0 3.9e-23 81.7 0.0 1.6 1 1 0 1 1 1 1 Macro domain DNA_pol_delta_4 PF04081.13 EMR67001.1 - 6.6e-44 149.4 5.0 9e-44 149.0 5.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Rrp15p PF07890.12 EMR67001.1 - 0.014 15.8 8.7 0.022 15.1 8.7 1.3 1 0 0 1 1 1 0 Rrp15p Spore_coat_CotO PF14153.6 EMR67001.1 - 0.1 12.5 6.9 0.13 12.1 6.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FAM176 PF14851.6 EMR67001.1 - 0.11 12.1 7.1 0.17 11.5 7.1 1.2 1 0 0 1 1 1 0 FAM176 family DUF2967 PF11179.8 EMR67002.1 - 3.4 5.6 4.2 3.5 5.6 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) TauD PF02668.16 EMR67003.1 - 7.2e-56 189.9 1.6 7.2e-56 189.9 1.6 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Beta_helix PF13229.6 EMR67003.1 - 0.01 15.7 0.1 0.017 15.0 0.1 1.4 1 1 0 1 1 1 0 Right handed beta helix region Glyco_hydro_43 PF04616.14 EMR67004.1 - 2.1e-34 119.2 2.5 3.3e-34 118.5 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 APH PF01636.23 EMR67004.1 - 8e-11 42.3 0.0 6.7e-10 39.3 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EMR67004.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EMR67004.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase tRNA_int_end_N2 PF12928.7 EMR67005.1 - 1.2e-23 83.1 0.0 6.3e-23 80.7 0.0 2.0 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term ThiF PF00899.21 EMR67006.1 - 9.4e-74 247.8 0.1 1.3e-73 247.3 0.1 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EMR67006.1 - 7.1e-22 77.8 0.9 7.1e-22 77.8 0.9 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EMR67006.1 - 3e-08 33.9 2.5 9.9e-06 25.6 0.6 2.6 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EMR67006.1 - 0.00032 21.1 0.2 0.001 19.5 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EMR67006.1 - 0.0048 17.2 0.6 0.056 13.7 0.6 2.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMR67006.1 - 0.0092 16.0 0.1 0.022 14.8 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EMR67006.1 - 0.011 16.2 0.1 0.24 12.0 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 EMR67007.1 - 3.3e-26 91.8 0.2 6.3e-26 90.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR67007.1 - 1.9e-15 58.1 0.0 4e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR67007.1 - 1.9e-08 34.2 0.0 3.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EMR67007.1 - 0.048 13.0 0.2 0.078 12.3 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EMR67007.1 - 0.051 13.8 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Q_salvage PF10343.9 EMR67009.1 - 1.8e-95 319.8 0.0 3.8e-72 243.2 0.0 2.1 1 1 1 2 2 2 2 Potential Queuosine, Q, salvage protein family DUF1563 PF07599.11 EMR67009.1 - 0.046 13.8 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) MAM PF00629.23 EMR67010.1 - 0.037 14.0 0.1 0.099 12.6 0.1 1.7 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu WD40 PF00400.32 EMR67011.1 - 3.9e-25 87.6 11.6 1.9e-07 31.7 0.6 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR67011.1 - 1e-15 57.8 1.4 0.0036 17.6 0.0 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EMR67011.1 - 0.00083 18.0 0.1 0.0096 14.5 0.1 2.0 1 1 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 EMR67011.1 - 0.0018 18.2 0.1 0.093 12.6 0.0 2.9 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EMR67011.1 - 0.025 13.9 0.2 12 5.1 0.0 3.2 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EMR67011.1 - 0.055 12.1 0.1 2.6 6.6 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Hira PF07569.11 EMR67011.1 - 0.056 13.2 0.4 0.8 9.4 0.0 2.5 2 1 0 2 2 2 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 EMR67011.1 - 0.067 12.1 1.3 6.9 5.5 0.0 3.4 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_binding_1 PF01035.20 EMR67012.1 - 2.2e-28 98.2 0.0 3.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ribosomal_60s PF00428.19 EMR67012.1 - 0.034 14.7 7.0 0.055 14.0 7.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.18 EMR67012.1 - 0.035 14.0 3.8 0.045 13.7 3.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CENP-N PF05238.13 EMR67012.1 - 0.047 13.0 1.0 0.058 12.7 1.0 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF4820 PF16091.5 EMR67012.1 - 0.14 11.5 2.0 0.2 11.0 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pro_Al_protease PF02983.14 EMR67013.1 - 2.4e-14 53.1 4.7 8.2e-14 51.4 4.7 2.0 1 0 0 1 1 1 1 Alpha-lytic protease prodomain MFS_1 PF07690.16 EMR67014.1 - 1.1e-06 27.8 25.9 1.1e-06 27.8 25.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR67014.1 - 1.6e-05 24.6 4.0 1.6e-05 24.6 4.0 2.5 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EMR67014.1 - 0.0057 15.6 8.3 0.01 14.8 8.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Sulfatase PF00884.23 EMR67015.1 - 2.4e-35 122.4 0.1 4.6e-35 121.5 0.1 1.4 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 EMR67015.1 - 0.078 12.9 0.0 0.73 9.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function F-box-like PF12937.7 EMR67016.1 - 7.3e-09 35.4 0.0 1.9e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR67016.1 - 1.1e-05 25.1 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Rhabdo_M2 PF04785.12 EMR67016.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 GPR_Gpa2_C PF11970.8 EMR67017.1 - 9.8e-15 54.4 3.6 1.5e-14 53.8 0.1 2.6 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Hydantoinase_B PF02538.14 EMR67018.1 - 6.4e-201 668.2 0.4 8.3e-201 667.9 0.4 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMR67018.1 - 8e-101 337.1 0.2 2.8e-100 335.3 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMR67018.1 - 1.9e-59 200.4 0.4 2.2e-57 193.6 0.0 3.2 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Arrestin_C PF02752.22 EMR67019.1 - 1.2e-12 48.4 0.1 1.6e-12 48.0 0.1 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain adh_short_C2 PF13561.6 EMR67020.1 - 2.7e-47 161.3 3.7 1.4e-45 155.7 3.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR67020.1 - 1.7e-45 154.9 3.4 1.1e-43 149.0 3.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR67020.1 - 3.2e-07 30.4 1.5 6.1e-07 29.5 1.5 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMR67020.1 - 0.0096 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EMR67020.1 - 0.019 14.3 0.0 0.13 11.6 0.0 2.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EMR67020.1 - 0.041 13.4 0.8 0.48 9.8 0.3 2.5 3 1 0 3 3 3 0 NAD dependent epimerase/dehydratase family Glyco_hydro_72 PF03198.14 EMR67021.1 - 3.8e-115 384.5 0.4 4.7e-115 384.2 0.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 EMR67021.1 - 0.013 14.6 0.7 0.029 13.5 0.7 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DAO PF01266.24 EMR67022.1 - 1.6e-28 100.3 0.0 4.1e-28 99.0 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR67022.1 - 4.2e-05 23.7 0.0 0.00014 22.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR67022.1 - 0.00017 20.8 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EMR67022.1 - 0.00079 19.9 0.0 1.3 9.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR67022.1 - 0.0015 18.6 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMR67022.1 - 0.0033 16.7 0.0 0.034 13.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR67022.1 - 0.0091 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMR67022.1 - 0.023 15.0 0.0 0.061 13.6 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.21 EMR67022.1 - 0.027 13.8 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 EMR67022.1 - 0.028 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EMR67022.1 - 0.064 12.5 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EMR67022.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EMR67022.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EMR67022.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_4 PF07993.12 EMR67023.1 - 4.8e-32 111.1 0.0 8.1e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EMR67023.1 - 2e-08 34.0 0.0 1.1e-07 31.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR67023.1 - 7e-06 26.3 0.1 2.5e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 EMR67023.1 - 0.00017 22.0 0.0 0.0009 19.7 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMR67023.1 - 0.0058 15.7 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family P2X_receptor PF00864.19 EMR67023.1 - 0.039 13.0 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 ATP P2X receptor GDP_Man_Dehyd PF16363.5 EMR67023.1 - 0.075 12.4 0.0 8.8 5.6 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Pro_isomerase PF00160.21 EMR67024.1 - 2.1e-43 148.3 0.0 2.3e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ubiquitin PF00240.23 EMR67025.1 - 0.024 14.4 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family Glyco_hydro_16 PF00722.21 EMR67026.1 - 7.1e-13 48.4 1.6 9.7e-13 48.0 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EMR67026.1 - 0.074 11.4 6.5 0.74 8.2 6.3 2.0 1 1 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Goodbye PF17109.5 EMR67027.1 - 6.1e-07 29.9 0.1 7.1e-07 29.7 0.1 1.0 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain GATase PF00117.28 EMR67028.1 - 3.3e-12 46.6 0.0 4.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMR67028.1 - 0.012 15.4 0.5 0.06 13.1 0.4 2.1 2 1 0 2 2 2 0 Peptidase C26 MFS_1 PF07690.16 EMR67029.1 - 1.5e-39 135.9 70.8 4.3e-32 111.4 38.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_8 PF13855.6 EMR67030.1 - 0.05 13.4 2.3 5.3 6.9 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 EMR67030.1 - 0.2 12.2 0.8 1.9 9.1 0.4 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) AA_permease PF00324.21 EMR67031.1 - 8.8e-101 337.8 28.1 9.9e-101 337.7 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR67031.1 - 2.3e-30 105.8 33.2 2.5e-30 105.7 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease Rax2 PF12768.7 EMR67033.1 - 0.0041 16.6 0.0 0.0068 15.9 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Gram_pos_anchor PF00746.21 EMR67033.1 - 0.028 14.3 0.9 0.062 13.3 0.9 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Romo1 PF10247.9 EMR67033.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 TMEM154 PF15102.6 EMR67033.1 - 0.2 11.5 2.2 0.23 11.4 0.0 2.1 3 0 0 3 3 3 0 TMEM154 protein family Podoplanin PF05808.11 EMR67033.1 - 0.22 11.6 5.7 0.21 11.7 3.9 1.7 1 1 1 2 2 2 0 Podoplanin Nitrate_red_gam PF02665.14 EMR67033.1 - 3.8 7.0 5.1 0.53 9.8 0.4 1.9 3 0 0 3 3 3 0 Nitrate reductase gamma subunit Trp_DMAT PF11991.8 EMR67034.1 - 6.4e-77 259.4 0.0 7.8e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Peptidase_M20 PF01546.28 EMR67035.1 - 6.2e-12 45.6 0.0 9.5e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR67035.1 - 6.9e-08 32.4 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Acetyltransf_1 PF00583.25 EMR67036.1 - 0.0027 17.9 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EMR67036.1 - 0.014 15.6 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Abi_HHR PF07815.14 EMR67037.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Abl-interactor HHR Sugar_tr PF00083.24 EMR67038.1 - 4.3e-57 194.0 14.9 3.8e-50 171.1 11.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR67038.1 - 4e-07 29.3 22.1 5.1e-07 28.9 22.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ketoacyl-synt PF00109.26 EMR67039.1 - 1.1e-66 225.0 0.0 2.1e-66 224.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR67039.1 - 7e-34 116.4 0.0 1.6e-33 115.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 EMR67039.1 - 1.5e-33 114.6 0.0 4.3e-33 113.0 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 EMR67039.1 - 1e-22 81.1 0.0 2.4e-20 73.3 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.12 EMR67039.1 - 2.1e-15 56.6 0.0 3.6e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 EMR67039.1 - 3.8e-14 53.2 0.0 1.7e-13 51.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 EMR67039.1 - 3.5e-11 43.3 0.4 1.3e-10 41.4 0.3 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EMR67039.1 - 5.4e-11 43.0 0.0 1.9e-10 41.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR67039.1 - 3.5e-08 33.4 0.0 9.3e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR67039.1 - 9.5e-08 32.6 0.0 6.5e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Amidase PF01425.21 EMR67039.1 - 3.7e-07 29.5 0.0 6.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Amidase Methyltransf_23 PF13489.6 EMR67039.1 - 1.6e-06 28.1 0.0 4.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EMR67039.1 - 2e-06 28.2 0.1 5e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EMR67039.1 - 2.8e-06 26.9 1.9 7.1e-06 25.6 0.0 2.4 3 0 0 3 3 3 1 Thiolase, N-terminal domain NodS PF05401.11 EMR67039.1 - 0.0097 15.5 0.0 0.036 13.7 0.0 1.9 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EMR67039.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 EMR67039.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF551 PF04448.12 EMR67039.1 - 0.74 10.8 2.8 6.4 7.8 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF551) Methyltransf_25 PF13649.6 EMR67040.1 - 1.1e-06 29.3 0.0 2.8e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR67040.1 - 1.7e-05 25.4 0.0 3.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR67040.1 - 2.5e-05 24.2 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR67040.1 - 6e-05 22.9 0.0 0.00044 20.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EMR67040.1 - 0.0037 17.4 0.0 0.0072 16.5 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 EMR67040.1 - 0.0067 17.2 0.0 0.016 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EMR67041.1 - 1.3e-19 70.4 0.0 3.3e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 EMR67041.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Dimerisation domain FAD_binding_4 PF01565.23 EMR67042.1 - 3.6e-14 52.7 0.3 9e-12 44.9 0.0 2.7 2 1 1 3 3 3 2 FAD binding domain BBE PF08031.12 EMR67042.1 - 5.9e-06 26.3 0.1 1.7e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EMR67043.1 - 3.1e-12 46.4 0.0 4.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF1479 PF07350.12 EMR67044.1 - 2.4e-113 379.0 0.8 2.1e-72 244.2 1.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 EMR67044.1 - 0.0077 16.5 0.4 0.57 10.4 0.1 2.4 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Amino_oxidase PF01593.24 EMR67047.1 - 2.7e-61 208.3 0.0 3.3e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR67047.1 - 4.5e-09 36.4 0.1 3.9e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR67047.1 - 0.00029 20.6 0.0 0.00074 19.2 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR67047.1 - 0.00098 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR67047.1 - 0.0035 16.6 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR67047.1 - 0.018 14.3 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 EMR67047.1 - 0.019 14.2 0.5 0.032 13.5 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EMR67047.1 - 0.022 13.4 0.4 0.034 12.8 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EMR67047.1 - 0.038 14.5 0.5 0.3 11.7 0.2 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR67047.1 - 0.14 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DIOX_N PF14226.6 EMR67048.1 - 3.8e-30 105.0 0.0 5.4e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR67048.1 - 1.1e-20 74.0 0.0 6.5e-20 71.5 0.0 2.2 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily IpaB_EvcA PF03278.13 EMR67048.1 - 0.15 11.8 0.0 2.4 7.9 0.1 2.1 2 0 0 2 2 2 0 IpaB/EvcA family adh_short PF00106.25 EMR67049.1 - 1.1e-20 73.9 0.0 1.9e-20 73.2 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67049.1 - 6.5e-13 48.8 0.0 8.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67049.1 - 0.0037 17.2 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR67049.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Snf7 PF03357.21 EMR67050.1 - 1.7e-36 125.4 3.5 2.2e-36 125.0 3.5 1.1 1 0 0 1 1 1 1 Snf7 OSCP PF00213.18 EMR67051.1 - 1.5e-44 152.2 4.5 2e-44 151.7 4.5 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Acyl_transf_1 PF00698.21 EMR67052.1 - 3.8e-50 171.2 0.0 6.6e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EMR67052.1 - 1.4e-44 152.6 0.0 7.6e-27 94.5 0.0 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EMR67052.1 - 1.3e-38 132.9 0.0 2.3e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EMR67052.1 - 7.1e-36 122.8 0.1 5.4e-35 120.0 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EMR67052.1 - 4.8e-23 82.0 0.6 1.8e-22 80.1 0.0 2.3 3 0 0 3 3 3 1 KR domain ADH_zinc_N_2 PF13602.6 EMR67052.1 - 4.3e-21 76.4 0.0 1.9e-17 64.6 0.0 3.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR67052.1 - 7.5e-17 61.5 0.0 7.2e-16 58.3 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EMR67052.1 - 3.7e-15 56.5 0.0 3.2e-14 53.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EMR67052.1 - 4.6e-13 49.6 0.0 2.2e-12 47.4 0.0 2.3 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EMR67052.1 - 8.1e-10 38.8 0.0 3.6e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR67052.1 - 1.2e-09 38.1 0.0 3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR67052.1 - 3.6e-09 37.2 0.0 2.5e-08 34.5 0.0 2.6 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR67052.1 - 5.5e-09 36.6 0.0 1.5e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR67052.1 - 0.0015 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 EMR67052.1 - 0.084 13.2 0.2 0.23 11.8 0.2 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_24 PF13578.6 EMR67052.1 - 0.097 13.7 0.0 0.41 11.7 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_3 PF13640.6 EMR67054.1 - 2.2e-08 34.9 0.0 6.4e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SNF2_N PF00176.23 EMR67055.1 - 1.1e-64 218.3 1.4 3.5e-64 216.7 1.4 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EMR67055.1 - 2.7e-49 166.9 14.2 2.7e-49 166.9 14.2 5.7 4 2 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 EMR67055.1 - 4.1e-20 72.2 0.0 1.1e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR67055.1 - 4e-05 23.7 0.0 4e-05 23.7 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EMR67055.1 - 0.0023 17.1 0.0 0.0023 17.1 0.0 3.0 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Lipase_3 PF01764.25 EMR67056.1 - 1.7e-21 76.5 0.0 3.1e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EMR67056.1 - 0.042 14.4 0.0 0.062 13.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family RAI16-like PF10257.9 EMR67057.1 - 4.5e-41 140.9 0.0 7.5e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Plasmodium_Vir PF05795.11 EMR67057.1 - 1.5 8.1 4.3 2.5 7.4 4.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SDA1 PF05285.12 EMR67057.1 - 3 7.2 13.6 4.9 6.5 13.6 1.2 1 0 0 1 1 1 0 SDA1 2OG-FeII_Oxy_3 PF13640.6 EMR67058.1 - 2.4e-08 34.7 0.2 2.3e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NigD_N PF12667.7 EMR67058.1 - 0.13 12.4 0.1 22 5.3 0.0 2.7 2 0 0 2 2 2 0 NigD-like N-terminal OB domain ABC_tran PF00005.27 EMR67059.1 - 7.1e-45 152.9 0.0 3.1e-21 76.3 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EMR67059.1 - 1.3e-19 70.0 7.3 1.3e-19 70.0 7.3 3.4 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EMR67059.1 - 5.8e-18 65.7 0.2 0.00025 20.9 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMR67059.1 - 1.7e-11 44.0 0.1 0.00019 21.0 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMR67059.1 - 1.2e-08 35.8 3.2 0.012 16.1 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EMR67059.1 - 4.8e-08 32.6 0.0 0.012 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMR67059.1 - 3.9e-07 30.1 0.6 0.0064 16.4 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 EMR67059.1 - 2.4e-06 28.1 1.1 0.03 14.9 0.0 3.3 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.23 EMR67059.1 - 3e-06 27.3 0.0 0.015 15.3 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EMR67059.1 - 4.2e-06 26.7 0.0 0.18 11.5 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 EMR67059.1 - 6.9e-06 26.4 1.4 2 8.8 0.0 3.6 3 0 0 3 3 3 2 RNA helicase AAA_16 PF13191.6 EMR67059.1 - 7.3e-06 26.5 0.0 0.036 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EMR67059.1 - 2.9e-05 24.4 0.0 0.17 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EMR67059.1 - 3.5e-05 24.1 0.0 0.016 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMR67059.1 - 6e-05 23.1 0.1 0.29 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 EMR67059.1 - 8.5e-05 23.0 0.0 0.59 10.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EMR67059.1 - 0.00014 21.8 0.1 0.2 11.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 EMR67059.1 - 0.00083 19.5 0.2 0.3 11.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EMR67059.1 - 0.001 19.1 0.0 2.7 8.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EMR67059.1 - 0.0026 17.5 0.3 2.2 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 EMR67059.1 - 0.0042 17.3 0.1 3.1 8.0 0.0 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF2813 PF11398.8 EMR67059.1 - 0.0043 16.4 0.5 0.8 8.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) NB-ARC PF00931.22 EMR67059.1 - 0.0044 16.2 0.3 5.6 6.1 0.0 3.3 3 1 0 3 3 3 0 NB-ARC domain AAA_27 PF13514.6 EMR67059.1 - 0.0083 15.7 0.0 2.1 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMR67059.1 - 0.011 15.3 0.0 1.3 8.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain GST_C_3 PF14497.6 EMR67059.1 - 0.012 15.7 0.1 0.03 14.5 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DAP3 PF10236.9 EMR67059.1 - 0.02 14.1 0.8 6.2 5.9 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 EMR67059.1 - 0.022 14.7 0.3 3.7 7.4 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EMR67059.1 - 0.032 14.2 0.0 2.7 7.9 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 EMR67059.1 - 0.036 13.6 0.4 2.4 7.7 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_30 PF13604.6 EMR67059.1 - 0.037 13.8 0.2 4.8 6.9 0.1 3.0 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EMR67059.1 - 0.04 14.0 1.2 29 4.7 0.0 3.6 3 1 1 4 4 4 0 Dynamin family DUF815 PF05673.13 EMR67059.1 - 0.042 13.0 0.0 3.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MCM PF00493.23 EMR67059.1 - 0.043 12.9 0.0 9.5 5.2 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain DUF87 PF01935.17 EMR67059.1 - 0.08 13.0 0.1 17 5.4 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain TsaE PF02367.17 EMR67059.1 - 0.087 12.8 0.2 19 5.3 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EMR67059.1 - 0.093 12.5 0.7 13 5.5 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EMR67059.1 - 0.14 11.7 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.6 EMR67059.1 - 0.23 11.9 4.3 5 7.6 0.0 3.3 4 0 0 4 4 3 0 AAA domain MeaB PF03308.16 EMR67059.1 - 0.23 10.4 1.1 13 4.6 0.0 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MAJIN PF15077.6 EMR67060.1 - 1.2 8.9 5.1 0.19 11.5 1.1 1.6 2 0 0 2 2 2 0 Membrane-anchored junction protein Hydrophobin PF01185.18 EMR67061.1 - 1.2e-12 48.3 7.8 1.7e-12 47.8 7.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DDHD PF02862.17 EMR67062.1 - 0.35 11.0 7.8 0.28 11.3 3.3 2.3 2 0 0 2 2 2 0 DDHD domain Sec3_C PF09763.9 EMR67063.1 - 3.6e-207 690.1 5.1 6e-194 646.3 1.6 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec3 Sec3_C_2 PF15278.6 EMR67063.1 - 0.021 15.2 0.5 3.7 8.0 0.0 3.3 3 0 0 3 3 3 0 Sec3 exocyst complex subunit PMC2NT PF08066.12 EMR67063.1 - 0.085 13.6 0.9 0.53 11.0 0.1 2.7 2 0 0 2 2 2 0 PMC2NT (NUC016) domain TBCC_N PF16752.5 EMR67063.1 - 0.14 12.6 4.7 15 6.0 0.0 4.3 4 0 0 4 4 4 0 Tubulin-specific chaperone C N-terminal domain FAD_binding_4 PF01565.23 EMR67064.1 - 1.3e-21 76.8 0.9 2.2e-21 76.0 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR67064.1 - 0.15 12.2 0.2 0.3 11.2 0.2 1.6 1 0 0 1 1 1 0 Berberine and berberine like MFS_1 PF07690.16 EMR67065.1 - 3.5e-31 108.4 22.9 1e-30 106.9 23.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.19 EMR67065.1 - 3.3 7.5 6.1 0.35 10.7 0.5 2.3 3 1 0 3 3 3 0 VIT family Formyl_trans_N PF00551.19 EMR67066.1 - 1.6e-21 76.8 0.0 2.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Peptidase_M30 PF10460.9 EMR67066.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M30 Fapy_DNA_glyco PF01149.24 EMR67067.1 - 3.8e-36 124.2 0.0 6.7e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EMR67067.1 - 4.9e-20 71.3 0.0 1.2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EMR67067.1 - 0.00016 20.6 1.8 0.019 13.8 0.0 2.9 2 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) Tannase PF07519.11 EMR67068.1 - 4.3e-120 401.8 1.9 6e-120 401.3 1.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EMR67068.1 - 0.026 14.0 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ribosomal_S14 PF00253.21 EMR67068.1 - 0.22 11.3 0.2 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Pribosyl_synth PF14572.6 EMR67069.1 - 1.3e-43 149.2 1.1 2.8e-37 128.5 0.3 2.1 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EMR67069.1 - 3.6e-15 55.8 0.2 5.8e-15 55.2 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran_N PF13793.6 EMR67069.1 - 9.5e-07 28.8 0.0 5.6e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase PEX11 PF05648.14 EMR67070.1 - 2.5e-70 236.4 0.4 2.9e-70 236.2 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Avian_gp85 PF03708.14 EMR67070.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.5 2 0 0 2 2 2 0 Avian retrovirus envelope protein, gp85 FBPase PF00316.20 EMR67071.1 - 2.6e-72 242.3 0.3 3.5e-72 241.8 0.3 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Cwf_Cwc_15 PF04889.12 EMR67072.1 - 1.5e-90 303.2 22.1 1.7e-90 303.1 22.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Glypican PF01153.19 EMR67072.1 - 0.15 10.9 5.9 0.2 10.4 5.9 1.1 1 0 0 1 1 1 0 Glypican Dsh_C PF12316.8 EMR67072.1 - 0.39 11.1 5.1 0.63 10.4 5.0 1.3 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SDA1 PF05285.12 EMR67072.1 - 0.88 8.9 25.8 1.1 8.6 25.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EMR67072.1 - 2.3 6.3 24.6 2.6 6.2 24.6 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 EMR67072.1 - 3.5 6.3 12.3 4.1 6.1 12.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 EMR67072.1 - 6.9 5.5 6.0 9 5.2 6.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAC1 PF16094.5 EMR67072.1 - 7.9 5.6 11.7 15 4.6 11.7 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 CDC45 PF02724.14 EMR67072.1 - 8.6 4.5 21.8 10 4.3 21.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Arf PF00025.21 EMR67073.1 - 7.3e-40 136.3 0.2 2.3e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 EMR67073.1 - 8.5e-14 51.5 0.0 1.5e-08 34.2 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EMR67073.1 - 1.4e-08 35.0 0.0 3.1e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EMR67073.1 - 4.9e-08 32.7 0.0 0.00082 19.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.12 EMR67073.1 - 1.9e-07 30.7 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMR67073.1 - 2.8e-07 30.2 0.0 9.2e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EMR67073.1 - 0.0022 18.1 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMR67073.1 - 0.004 16.7 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Lipase_GDSL_2 PF13472.6 EMR67075.1 - 5.3e-10 40.0 0.2 7.1e-09 36.3 0.2 2.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family SBDS_C PF09377.10 EMR67076.1 - 4.6e-46 155.6 0.1 8.5e-46 154.7 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EMR67076.1 - 5.9e-34 116.0 0.0 1.1e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SUIM_assoc PF16619.5 EMR67076.1 - 8e-05 22.6 6.4 0.055 13.5 2.6 2.5 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 IHABP4_N PF16174.5 EMR67076.1 - 0.31 11.6 9.3 0.59 10.7 9.3 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Vps39_1 PF10366.9 EMR67076.1 - 0.59 10.4 2.0 7.6 6.9 0.1 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DUF3050 PF11251.8 EMR67077.1 - 0.09 12.4 0.5 0.45 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3050) PBP PF01161.20 EMR67079.1 - 1.3e-17 64.3 0.0 1.8e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ParB PF08775.10 EMR67081.1 - 0.052 14.0 0.5 0.53 10.8 0.1 2.1 2 0 0 2 2 2 0 ParB family Pkinase PF00069.25 EMR67082.1 - 3.7e-08 33.0 0.0 0.035 13.5 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EMR67082.1 - 0.00011 21.6 0.0 0.083 12.2 0.0 3.1 1 1 1 2 2 2 2 Protein tyrosine kinase Ribosomal_S13 PF00416.22 EMR67083.1 - 4.3e-55 185.6 3.0 5e-55 185.4 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EMR67083.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 EMR67083.1 - 0.035 14.5 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Syntaxin-6_N PF09177.11 EMR67083.1 - 0.15 12.7 0.0 0.4 11.3 0.0 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Peptidase_S10 PF00450.22 EMR67084.1 - 2.6e-131 438.9 4.0 3.1e-131 438.6 4.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EMR67084.1 - 1.4e-11 45.0 0.0 3.1e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Cas1_AcylT PF07779.12 EMR67085.1 - 2.3e-38 132.4 0.0 3.6e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Peptidase_S10 PF00450.22 EMR67086.1 - 5.7e-84 283.0 0.3 9.2e-84 282.3 0.3 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Ribonuclease PF00545.20 EMR67087.1 - 1.9e-08 34.9 0.0 2.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 ribonuclease HpcH_HpaI PF03328.14 EMR67088.1 - 9.1e-34 116.5 0.0 1.1e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DENN PF02141.21 EMR67089.1 - 2.7e-39 135.0 0.0 4.5e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Elongin_A PF06881.11 EMR67089.1 - 0.016 15.8 5.0 0.043 14.3 3.4 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A BRE1 PF08647.11 EMR67089.1 - 9.5 6.4 14.7 1.7 8.7 3.0 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Pkinase PF00069.25 EMR67090.1 - 7.4e-05 22.2 0.0 0.0067 15.8 0.0 3.0 3 1 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR67090.1 - 0.00026 20.4 0.0 0.069 12.4 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase Herpes_UL32 PF06070.11 EMR67090.1 - 0.78 7.4 1.9 1.1 6.9 1.9 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 PBP1_TM PF14812.6 EMR67090.1 - 3.1 8.2 9.7 0.18 12.2 3.1 2.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FoP_duplication PF13865.6 EMR67090.1 - 9.9 6.8 11.8 26 5.5 11.8 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 cobW PF02492.19 EMR67092.1 - 3.5e-40 137.5 0.0 4.8e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EMR67092.1 - 0.00098 19.0 0.0 0.0028 17.6 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.14 EMR67092.1 - 0.023 14.6 0.0 0.23 11.4 0.0 2.6 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 EMR67092.1 - 0.031 14.6 0.0 0.078 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EMR67092.1 - 0.032 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EMR67092.1 - 0.059 12.6 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF463 PF04317.12 EMR67092.1 - 0.09 11.7 0.1 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 YcjX-like family, DUF463 TrwB_AAD_bind PF10412.9 EMR67092.1 - 0.093 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 EMR67092.1 - 0.15 12.6 0.0 0.32 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nop14 PF04147.12 EMR67093.1 - 0.002 16.5 14.2 0.002 16.5 14.2 1.2 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 EMR67093.1 - 0.011 14.3 13.9 0.0096 14.4 13.9 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 EMR67093.1 - 0.014 14.9 16.4 0.014 14.8 16.4 1.2 1 0 0 1 1 1 0 SDA1 DDRGK PF09756.9 EMR67093.1 - 0.039 13.5 9.9 0.054 13.1 9.9 1.2 1 0 0 1 1 1 0 DDRGK domain BUD22 PF09073.10 EMR67093.1 - 0.045 13.1 12.4 0.043 13.2 12.4 1.1 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.10 EMR67093.1 - 0.24 12.1 15.9 0.36 11.5 15.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Connexin PF00029.19 EMR67093.1 - 0.28 10.9 0.6 0.32 10.7 0.6 1.2 1 0 0 1 1 1 0 Connexin DUF2722 PF10846.8 EMR67093.1 - 0.51 9.2 5.8 0.53 9.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 EMR67093.1 - 0.66 8.2 17.1 0.93 7.7 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EMR67093.1 - 0.96 8.4 2.9 1.1 8.1 2.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HSP90 PF00183.18 EMR67093.1 - 1.2 8.0 16.1 1.3 7.8 16.1 1.1 1 0 0 1 1 1 0 Hsp90 protein DNA_pol_phi PF04931.13 EMR67093.1 - 1.2 7.1 31.0 1.6 6.8 31.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4820 PF16091.5 EMR67093.1 - 1.4 8.2 6.0 1.8 7.9 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 EMR67093.1 - 1.9 8.3 8.9 2.6 7.8 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 EMR67093.1 - 1.9 7.8 20.1 2.7 7.3 20.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.11 EMR67093.1 - 2.2 6.7 13.0 2.1 6.8 13.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ABC_trans_N PF14510.6 EMR67093.1 - 2.2 9.0 5.9 28 5.4 0.0 2.3 2 0 0 2 2 2 0 ABC-transporter N-terminal NOA36 PF06524.12 EMR67093.1 - 2.3 7.4 24.3 3.3 6.9 24.3 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EMR67093.1 - 2.9 7.5 20.3 4.7 6.9 20.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ORC_WH_C PF18137.1 EMR67093.1 - 2.9 7.9 10.5 4.1 7.5 10.5 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Pox_Ag35 PF03286.14 EMR67093.1 - 3.7 7.3 13.5 5.5 6.7 13.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 EMR67093.1 - 3.8 7.5 13.9 7.7 6.5 13.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal RPA43_OB PF17875.1 EMR67093.1 - 3.9 8.1 11.3 5.3 7.7 11.3 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I TFB6 PF17110.5 EMR67093.1 - 3.9 7.2 14.6 7.4 6.3 14.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Rhabdo_ncap PF00945.18 EMR67093.1 - 4.5 6.1 10.0 6.9 5.4 10.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2457 PF10446.9 EMR67093.1 - 5.1 6.1 31.3 6.5 5.8 31.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SF1-HH PF16275.5 EMR67096.1 - 3.4e-44 149.8 1.1 3.4e-44 149.8 1.1 2.5 1 1 1 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EMR67096.1 - 1.7e-12 46.8 11.7 2.5e-06 27.3 1.1 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EMR67096.1 - 2.6e-08 33.6 0.1 4.9e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EMR67096.1 - 3.4e-07 30.1 7.9 0.0016 18.4 3.3 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EMR67096.1 - 0.00011 22.0 8.2 0.081 12.8 0.5 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EMR67096.1 - 0.002 17.8 5.0 0.43 10.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EMR67096.1 - 0.1 12.5 0.4 0.1 12.5 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 EMR67096.1 - 3.9 7.9 8.3 3.8 7.9 0.9 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Prim_Zn_Ribbon PF08273.12 EMR67096.1 - 5.3 7.4 7.9 0.66 10.3 3.2 1.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase ECH_1 PF00378.20 EMR67097.1 - 2e-23 83.0 0.0 2.7e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMR67097.1 - 4.2e-07 29.8 0.0 5.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ras PF00071.22 EMR67098.1 - 8.6e-35 119.7 0.0 1.1e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR67098.1 - 3e-17 62.9 0.0 4.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR67098.1 - 0.002 17.6 0.0 0.0037 16.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMR67098.1 - 0.033 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TRAPP PF04051.16 EMR67099.1 - 3.7e-33 114.3 0.0 4.6e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3678 PF12435.8 EMR67099.1 - 0.038 13.4 0.7 0.038 13.4 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3678) DUF2423 PF10338.9 EMR67100.1 - 1.6e-19 69.8 6.7 1.6e-19 69.8 6.7 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2423) PINIT PF14324.6 EMR67101.1 - 1.7e-27 96.6 0.1 4.4e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 PINIT domain HU-HIG PF18291.1 EMR67101.1 - 0.023 14.8 0.0 0.067 13.3 0.0 1.6 1 1 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Alpha_L_fucos PF01120.17 EMR67102.1 - 1.2e-66 225.5 10.8 1.8e-38 132.9 10.9 2.2 1 1 1 2 2 2 2 Alpha-L-fucosidase AP3B1_C PF14796.6 EMR67102.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal DUF2272 PF10030.9 EMR67102.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2272) DUF1996 PF09362.10 EMR67103.1 - 3.7e-83 279.1 0.9 6e-83 278.4 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) F-box-like PF12937.7 EMR67104.1 - 9.9e-05 22.2 0.4 0.00029 20.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like HhH-GPD PF00730.25 EMR67105.1 - 2e-19 70.0 0.0 6.5e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 EMR67105.1 - 1.2e-18 67.0 0.0 2.8e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 EMR67105.1 - 6.7e-06 25.7 0.1 1.7e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Glyco_hydro_92 PF07971.12 EMR67106.1 - 1.1e-145 486.1 0.1 1.3e-145 485.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMR67106.1 - 3.5e-56 190.8 0.0 7.2e-56 189.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain SSI PF00720.17 EMR67106.1 - 0.054 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Subtilisin inhibitor-like CBM_6 PF03422.15 EMR67106.1 - 0.087 13.1 0.1 0.88 9.9 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) Sec23_trunk PF04811.15 EMR67107.1 - 4.2e-51 173.9 0.0 1.2e-50 172.4 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EMR67107.1 - 1.3e-22 79.6 0.0 2.3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EMR67107.1 - 2.6e-16 60.1 0.0 4.7e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EMR67107.1 - 6.6e-15 54.9 3.9 1.9e-14 53.4 3.9 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EMR67107.1 - 0.00015 21.6 0.0 0.00039 20.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Glyco_hydro_92 PF07971.12 EMR67108.1 - 3.6e-137 458.0 0.1 4.6e-137 457.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMR67108.1 - 2.9e-63 214.0 0.2 5e-63 213.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_79C PF16862.5 EMR67109.1 - 4.5e-19 69.2 1.5 9.7e-19 68.2 1.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF948 PF06103.11 EMR67110.1 - 2.9 8.2 7.3 75 3.7 0.3 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3040 PF11239.8 EMR67110.1 - 5.6 7.3 6.4 3.3 8.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Lactamase_B_6 PF16661.5 EMR67111.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain DUF4148 PF13663.6 EMR67112.1 - 4.9 7.4 8.0 1.9 8.8 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) zf-H2C2 PF09337.10 EMR67113.1 - 4.5e-10 39.6 0.2 1.2e-09 38.2 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EMR67113.1 - 5.5e-07 29.6 0.1 1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EMR67113.1 - 2.1e-06 28.0 0.0 3.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMR67113.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMR67113.1 - 0.002 18.8 0.0 0.0031 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR67113.1 - 0.04 13.9 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.7 EMR67113.1 - 0.097 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR67113.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_92 PF07971.12 EMR67114.1 - 6.1e-126 421.0 0.0 8.6e-102 341.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMR67114.1 - 2.3e-59 201.2 0.5 3.6e-59 200.5 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain adh_short PF00106.25 EMR67115.1 - 1.8e-17 63.4 0.0 2.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67115.1 - 4.7e-09 36.2 0.0 6.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67115.1 - 6.2e-08 32.8 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR67115.1 - 8.6e-05 22.1 0.0 0.00018 21.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMR67115.1 - 0.016 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.13 EMR67115.1 - 0.16 11.9 0.0 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Shikimate_DH PF01488.20 EMR67115.1 - 0.18 11.8 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amidohydro_3 PF07969.11 EMR67117.1 - 2.4e-12 47.1 3.2 1.1e-11 44.9 0.1 2.9 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_1 PF01979.20 EMR67117.1 - 1.9e-09 37.3 0.6 2.6e-08 33.6 0.0 2.6 3 0 0 3 3 3 1 Amidohydrolase family Lactamase_B_6 PF16661.5 EMR67118.1 - 1.6e-65 220.2 0.0 2.3e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 EMR67118.1 - 6.6e-17 61.8 0.0 2.2e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_2 PF12706.7 EMR67118.1 - 0.02 14.4 0.0 0.1 12.1 0.0 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Asp PF00026.23 EMR67119.1 - 1.3e-30 106.9 0.1 3.3e-30 105.6 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR67119.1 - 1.7e-05 25.1 0.8 0.00037 20.8 0.8 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EMR67119.1 - 0.13 12.8 0.1 18 6.0 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SIR2_2 PF13289.6 EMR67122.1 - 8.4e-18 64.9 0.0 1.7e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 SIR2-like domain AbiH PF14253.6 EMR67122.1 - 0.06 13.2 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH CBP4 PF07960.11 EMR67123.1 - 1e-30 106.3 0.7 1.2e-30 106.0 0.7 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.10 EMR67123.1 - 0.059 13.2 0.4 0.1 12.4 0.4 1.7 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2852 PF11014.8 EMR67123.1 - 3.4 7.8 6.9 0.8 9.9 2.8 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2852) RRM_1 PF00076.22 EMR67124.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 EMR67125.1 - 6.2e-15 56.0 0.0 8.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 SET domain Aconitase PF00330.20 EMR67126.1 - 1.3e-72 245.3 0.0 3.8e-71 240.5 0.0 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMR67126.1 - 8.2e-26 90.9 0.0 1.8e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain SecE PF00584.20 EMR67127.1 - 2.3e-14 53.0 0.0 2.6e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 EMR67128.1 - 3.1e-19 68.9 15.5 1.5e-05 25.6 0.8 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR67128.1 - 1.7e-05 25.0 0.0 0.0027 18.0 0.0 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EMR67128.1 - 9.1e-05 21.1 0.7 0.12 10.9 0.0 3.8 4 0 0 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.12 EMR67128.1 - 0.027 14.4 0.7 0.33 11.0 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TAP42 PF04177.12 EMR67128.1 - 0.2 10.7 1.1 0.31 10.1 1.1 1.2 1 0 0 1 1 1 0 TAP42-like family WD40_like PF17005.5 EMR67128.1 - 0.27 10.5 0.2 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Histidinol_dh PF00815.20 EMR67129.1 - 7.2e-161 535.8 3.5 1e-160 535.3 3.5 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EMR67129.1 - 7.2e-24 83.4 0.1 1.4e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EMR67129.1 - 1.8e-13 50.7 0.1 9.1e-13 48.5 0.2 2.2 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase Tannase PF07519.11 EMR67130.1 - 5.6e-110 368.4 0.6 6.6e-110 368.2 0.6 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Enolase_C PF00113.22 EMR67130.1 - 0.35 10.1 0.9 0.66 9.2 0.0 1.7 2 0 0 2 2 2 0 Enolase, C-terminal TIM barrel domain Syntaxin PF00804.25 EMR67131.1 - 1.8e-20 73.4 17.7 6e-20 71.8 17.7 1.7 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 EMR67131.1 - 1.8e-12 47.0 0.5 1.8e-12 47.0 0.5 2.9 2 1 1 3 3 3 1 SNARE domain SKA2 PF16740.5 EMR67131.1 - 0.011 15.6 0.3 0.011 15.6 0.3 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Allexi_40kDa PF05549.11 EMR67131.1 - 0.08 12.4 6.7 0.13 11.7 0.9 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein HEPN_Toprim_N PF18871.1 EMR67131.1 - 0.11 12.4 0.9 0.17 11.8 0.9 1.3 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 DUF1664 PF07889.12 EMR67131.1 - 0.12 12.4 9.7 3 7.9 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EMR67131.1 - 0.15 12.1 13.0 0.31 11.1 1.9 2.5 2 1 0 2 2 2 0 Laminin Domain II DASH_Dam1 PF08653.10 EMR67131.1 - 0.24 11.2 3.4 3.4 7.5 0.4 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 WXG100 PF06013.12 EMR67131.1 - 0.35 11.1 14.6 1.6 9.1 2.8 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG AAA_13 PF13166.6 EMR67131.1 - 0.54 8.8 12.1 0.28 9.8 2.1 2.0 1 1 1 2 2 2 0 AAA domain DUF3323 PF11796.8 EMR67131.1 - 1 9.2 10.4 1.5 8.6 9.1 1.8 1 1 1 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DUF4349 PF14257.6 EMR67131.1 - 1.1 8.7 16.2 0.071 12.5 4.2 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4349) Occludin_ELL PF07303.13 EMR67131.1 - 1.2 9.9 7.1 22 5.9 0.1 3.2 2 1 0 2 2 2 0 Occludin homology domain Seryl_tRNA_N PF02403.22 EMR67131.1 - 1.8 8.8 9.7 4.4 7.6 0.9 3.1 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4298 PF14131.6 EMR67131.1 - 2.5 8.1 5.6 1 9.3 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) BLOC1_2 PF10046.9 EMR67131.1 - 2.9 8.3 10.9 1.7 9.0 1.5 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF883 PF05957.13 EMR67131.1 - 5 7.8 11.6 0.6 10.8 4.0 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DAP10 PF07213.11 EMR67132.1 - 0.077 13.0 0.7 0.15 12.0 0.7 1.4 1 0 0 1 1 1 0 DAP10 membrane protein VSP PF03302.13 EMR67132.1 - 0.19 10.6 1.7 0.25 10.2 1.7 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein AlaDh_PNT_N PF05222.15 EMR67133.1 - 3.9e-28 98.5 0.0 5.5e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EMR67133.1 - 7.7e-06 25.4 0.0 3.3e-05 23.3 0.0 1.8 1 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.18 EMR67134.1 - 3.9e-08 33.3 12.4 6.5e-08 32.6 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.17 EMR67135.1 - 2.3 8.2 13.6 3.3 7.7 13.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Memo PF01875.17 EMR67136.1 - 3.1e-58 197.1 0.0 9.3e-57 192.2 0.0 2.0 1 1 0 1 1 1 1 Memo-like protein DUF4830 PF16112.5 EMR67137.1 - 0.082 13.4 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4830) RNA_binding PF01877.17 EMR67137.1 - 0.12 12.7 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA binding Cupin_2 PF07883.11 EMR67139.1 - 0.04 13.6 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Cupin domain MFS_1 PF07690.16 EMR67140.1 - 9.5e-33 113.6 25.1 1.4e-32 113.0 25.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF21 PF01595.20 EMR67140.1 - 0.38 10.4 4.4 1.3 8.8 2.4 2.5 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain Glyco_hydro_88 PF07470.13 EMR67141.1 - 1.2e-91 307.3 3.5 1.4e-91 307.2 3.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EMR67141.1 - 0.00024 19.7 0.5 0.00035 19.2 0.5 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 EMR67141.1 - 0.0049 16.4 10.0 0.088 12.3 2.4 3.1 1 1 2 3 3 3 2 Glycosyl hydrolase family 76 MiaE PF06175.11 EMR67141.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) IDO PF01231.18 EMR67142.1 - 6.4e-141 470.1 0.0 7.3e-141 469.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 EMR67142.1 - 0.0022 16.8 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) DUF5023 PF16426.5 EMR67142.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5023) Methyltransf_23 PF13489.6 EMR67143.1 - 4.3e-15 55.9 0.0 5.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR67143.1 - 1e-09 38.9 0.0 2.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR67143.1 - 9e-09 35.3 0.0 2.6e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR67143.1 - 1e-08 35.7 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMR67143.1 - 6.4e-06 25.7 0.0 2.7e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 EMR67143.1 - 0.00014 22.5 0.0 0.00038 21.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EMR67143.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 EMR67143.1 - 0.0039 17.3 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 EMR67143.1 - 0.0049 16.7 0.0 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 EMR67143.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EMR67143.1 - 0.039 13.3 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 EMR67143.1 - 0.043 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.20 EMR67143.1 - 0.17 11.1 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GidB PF02527.15 EMR67143.1 - 0.25 10.6 0.0 2.7 7.3 0.0 2.1 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G QRPTase_C PF01729.19 EMR67144.1 - 3.2e-55 186.5 0.1 3.8e-55 186.2 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EMR67144.1 - 3.6e-18 65.4 0.0 2.5e-17 62.7 0.0 2.4 3 1 0 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ubie_methyltran PF01209.18 EMR67146.1 - 8.6e-59 198.7 0.0 1e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EMR67146.1 - 2.4e-10 41.0 0.0 3.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR67146.1 - 6.6e-08 33.1 0.0 1e-07 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR67146.1 - 1.9e-07 31.7 0.0 3.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR67146.1 - 3.3e-05 23.7 0.0 4.9e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR67146.1 - 0.003 17.4 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EMR67146.1 - 0.17 11.7 0.0 1.9 8.3 0.0 2.3 3 0 0 3 3 3 0 Hypothetical methyltransferase NmrA PF05368.13 EMR67147.1 - 3.4e-12 46.4 0.0 1.6e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR67147.1 - 3.1e-10 40.3 0.2 6.2e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EMR67147.1 - 0.0027 18.1 0.0 0.0054 17.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMR67147.1 - 0.069 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ATP-grasp_3 PF02655.14 EMR67149.1 - 8.9e-10 38.8 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EMR67149.1 - 0.00042 19.9 0.0 0.0011 18.6 0.0 1.6 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus RimK PF08443.11 EMR67149.1 - 0.00057 19.5 0.0 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 EMR67149.1 - 0.017 14.4 0.0 0.068 12.4 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp FolB PF02152.18 EMR67149.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Dihydroneopterin aldolase LtrA PF06772.11 EMR67150.1 - 7e-09 35.4 22.7 1.6e-08 34.2 4.2 3.1 2 1 1 3 3 3 2 Bacterial low temperature requirement A protein (LtrA) MnhB PF04039.13 EMR67150.1 - 1.2 9.4 6.4 0.37 11.1 0.3 2.7 2 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter PNP_UDP_1 PF01048.20 EMR67151.1 - 4.4e-09 35.9 0.0 1.5e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily GST_N PF02798.20 EMR67152.1 - 5.1e-15 55.6 0.0 1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR67152.1 - 6.4e-15 55.3 0.0 1.4e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMR67152.1 - 5.4e-13 49.0 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EMR67152.1 - 2.9e-05 24.2 0.0 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.6 EMR67152.1 - 0.0026 17.8 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR67152.1 - 0.0026 17.9 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMR67152.1 - 0.014 16.0 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR67152.1 - 0.098 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 EMR67153.1 - 8.5e-13 47.9 33.3 4.9e-08 32.3 9.1 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily CFEM PF05730.11 EMR67154.1 - 1.1e-08 35.1 7.7 1.7e-08 34.5 7.7 1.3 1 0 0 1 1 1 1 CFEM domain RFC1 PF08519.12 EMR67155.1 - 8e-58 195.0 0.2 7.1e-57 192.0 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EMR67155.1 - 9.1e-16 58.0 0.0 2.2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EMR67155.1 - 5.2e-09 36.6 0.0 1.6e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMR67155.1 - 4.9e-05 23.6 0.2 0.00016 21.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain DNA_pol3_delta PF06144.13 EMR67155.1 - 8.3e-05 22.4 0.0 0.00043 20.1 0.0 2.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EMR67155.1 - 8.7e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EMR67155.1 - 0.0019 18.6 0.1 0.014 15.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EMR67155.1 - 0.0026 17.8 0.0 0.0066 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMR67155.1 - 0.014 15.6 0.0 0.07 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMR67155.1 - 0.017 15.6 0.1 0.017 15.6 0.1 2.7 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 EMR67155.1 - 0.02 15.3 3.5 2.6 8.5 0.1 3.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMR67155.1 - 0.044 13.5 0.0 0.044 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMR67155.1 - 0.065 13.2 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 EMR67155.1 - 0.074 12.9 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 NTPase PTCB-BRCT PF12738.7 EMR67155.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain AAA_28 PF13521.6 EMR67155.1 - 0.11 12.8 1.7 0.73 10.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.12 EMR67155.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Glyco_hydro_18 PF00704.28 EMR67156.1 - 1.2e-55 189.4 0.2 1.5e-55 189.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1996 PF09362.10 EMR67157.1 - 5.4e-80 268.8 4.5 8.4e-80 268.1 4.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF4071 PF13281.6 EMR67158.1 - 0.11 11.5 2.8 0.21 10.6 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DciA PF05258.12 EMR67159.1 - 0.026 14.9 0.1 0.048 14.1 0.1 1.3 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA FAIM1 PF06905.13 EMR67159.1 - 0.064 13.0 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Glyco_hydro_88 PF07470.13 EMR67160.1 - 8.5e-47 159.9 3.6 1e-46 159.6 3.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Rgp1 PF08737.10 EMR67161.1 - 6.3e-160 532.9 0.0 8.6e-160 532.5 0.0 1.2 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 EMR67161.1 - 0.0044 17.1 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EMR67161.1 - 0.0058 17.1 0.0 0.068 13.6 0.0 2.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain SGT1 PF07093.11 EMR67161.1 - 0.12 10.8 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 SGT1 protein FAM176 PF14851.6 EMR67161.1 - 0.21 11.2 0.7 0.62 9.7 0.7 1.7 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EMR67161.1 - 0.33 10.2 9.4 0.49 9.7 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 EMR67161.1 - 1.1 9.7 8.3 2.4 8.6 8.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EMR67161.1 - 1.4 9.4 16.1 0.77 10.2 12.2 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EMR67161.1 - 1.6 6.7 8.7 2.2 6.3 8.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EMR67161.1 - 2.4 7.2 11.9 3.8 6.5 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 EMR67161.1 - 7.8 4.6 5.3 11 4.0 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family DASH_Dad3 PF08656.10 EMR67162.1 - 2.2e-34 117.3 0.4 2.7e-34 117.1 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 VBS PF08913.10 EMR67162.1 - 0.15 12.5 0.0 0.57 10.6 0.0 1.6 1 1 0 1 1 1 0 Vinculin Binding Site Ribosomal_S5_C PF03719.15 EMR67163.1 - 3.1e-21 74.6 0.1 6.3e-21 73.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EMR67163.1 - 8.8e-17 60.9 0.1 1.8e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain CorA PF01544.18 EMR67164.1 - 0.00023 20.6 0.0 0.0005 19.5 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_1 PF00561.20 EMR67165.1 - 8.6e-19 68.2 0.5 1.7e-12 47.5 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR67165.1 - 3.8e-10 39.5 0.0 4.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR67165.1 - 2.8e-08 34.6 0.0 1e-05 26.2 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EMR67165.1 - 0.086 12.4 0.2 0.23 11.0 0.1 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Ac76 PF05814.11 EMR67166.1 - 0.0045 17.0 0.1 0.0058 16.6 0.1 1.1 1 0 0 1 1 1 1 Orf76 (Ac76) OAD_gamma PF04277.13 EMR67166.1 - 0.01 16.4 0.1 0.019 15.5 0.1 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DcuC PF03606.15 EMR67166.1 - 0.019 13.5 0.6 0.44 8.9 0.1 1.9 1 1 1 2 2 2 0 C4-dicarboxylate anaerobic carrier DUF4834 PF16118.5 EMR67166.1 - 0.04 14.9 0.0 0.046 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Baculo_11_kDa PF06143.11 EMR67166.1 - 0.049 13.2 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Vpu PF00558.19 EMR67166.1 - 0.076 12.8 0.2 0.1 12.4 0.2 1.2 1 0 0 1 1 1 0 Vpu protein Chordopox_A13L PF05961.11 EMR67166.1 - 0.11 12.8 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Comm PF15957.5 EMR67166.1 - 0.13 12.6 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 Commissureless Holin_BhlA PF10960.8 EMR67166.1 - 0.26 11.3 2.2 0.85 9.6 2.2 1.8 1 1 1 2 2 2 0 BhlA holin family CLASP_N PF12348.8 EMR67167.1 - 8.9e-119 395.1 1.2 1.6e-86 289.5 0.0 4.3 4 1 1 5 5 5 3 CLASP N terminal HEAT PF02985.22 EMR67167.1 - 0.0013 18.8 0.7 12 6.5 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Glyco_hydro_92 PF07971.12 EMR67170.1 - 5.1e-72 243.3 0.1 7.9e-72 242.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMR67170.1 - 1.5e-35 123.2 1.1 2.2e-35 122.7 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Iso_dh PF00180.20 EMR67171.1 - 2.4e-99 332.8 0.0 3e-99 332.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EMR67171.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 IclR PF01614.18 EMR67171.1 - 0.074 12.9 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial transcriptional regulator Sec5 PF15469.6 EMR67172.1 - 2e-27 96.3 0.0 1.3e-19 70.8 0.0 2.9 1 1 1 2 2 2 2 Exocyst complex component Sec5 HlyE PF06109.13 EMR67172.1 - 0.0092 15.3 0.5 0.069 12.4 0.3 2.2 2 0 0 2 2 2 1 Haemolysin E (HlyE) PTS_IIA PF02255.16 EMR67172.1 - 0.064 13.3 0.7 25 5.0 0.0 3.5 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit BSP PF04450.12 EMR67173.1 - 6.6e-79 264.5 0.0 8.3e-79 264.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Menin PF05053.13 EMR67173.1 - 0.12 10.7 3.1 0.16 10.3 3.1 1.1 1 0 0 1 1 1 0 Menin AF-4 PF05110.13 EMR67173.1 - 0.88 7.6 12.7 1.1 7.2 12.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NST1 PF13945.6 EMR67173.1 - 6.4 6.8 7.7 11 6.1 7.7 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Acetyltransf_7 PF13508.7 EMR67174.1 - 4.4e-06 27.0 0.0 9.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR67174.1 - 2.3e-05 24.3 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR67174.1 - 9.5e-05 22.6 0.0 0.00022 21.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Spt20 PF12090.8 EMR67174.1 - 0.53 9.8 3.2 1.1 8.8 3.2 1.4 1 0 0 1 1 1 0 Spt20 family rRNA_processing PF08524.11 EMR67175.1 - 0.0094 16.0 33.9 1.4 8.9 33.9 2.2 1 1 0 1 1 1 1 rRNA processing DUF3245 PF11595.8 EMR67175.1 - 0.017 15.6 14.8 0.017 15.6 14.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3245) RhoGAP PF00620.27 EMR67176.1 - 1.8e-46 157.7 1.3 6.1e-46 156.0 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain CENP-F_leu_zip PF10473.9 EMR67176.1 - 0.41 10.7 21.5 0.05 13.6 15.4 2.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 EMR67176.1 - 0.65 9.3 6.8 1.1 8.6 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ARD PF03079.14 EMR67176.1 - 1.1 9.4 4.5 0.3 11.2 0.6 2.0 2 0 0 2 2 2 0 ARD/ARD' family NPV_P10 PF05531.12 EMR67176.1 - 2.7 8.5 4.6 5.2 7.6 0.1 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 EMR67176.1 - 4.6 7.7 13.2 11 6.4 13.2 1.6 1 0 0 1 1 1 0 Fez1 Zn-ribbon_8 PF09723.10 EMR67177.1 - 0.011 15.8 0.2 0.024 14.8 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-BED PF02892.15 EMR67177.1 - 0.049 13.7 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 BED zinc finger Rubella_E2 PF05749.11 EMR67177.1 - 4.7 6.6 7.3 3 7.2 4.3 2.1 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 Dehydrin PF00257.19 EMR67177.1 - 5.3 7.6 7.7 2 9.0 2.6 2.3 2 0 0 2 2 2 0 Dehydrin SRP68 PF16969.5 EMR67178.1 - 3.9e-203 676.5 6.7 4.8e-203 676.2 6.7 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Cu-oxidase_3 PF07732.15 EMR67178.1 - 5.1e-35 120.1 8.8 1.7e-27 95.8 3.4 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EMR67178.1 - 1.3e-17 64.3 0.0 2.9e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase DUF4699 PF15770.5 EMR67178.1 - 0.019 14.7 2.2 0.067 13.0 2.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) DUF1525 PF07511.11 EMR67178.1 - 0.098 12.8 0.5 8.8 6.5 0.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1525) Pex14_N PF04695.13 EMR67178.1 - 2 9.1 8.2 0.58 10.8 1.8 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1295 PF06966.12 EMR67179.1 - 3.7e-24 85.6 0.0 5e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EMR67179.1 - 0.0023 18.3 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EMR67179.1 - 0.07 13.5 0.3 0.21 12.0 0.1 1.9 2 0 0 2 2 2 0 Phospholipid methyltransferase Steroid_dh PF02544.16 EMR67179.1 - 0.2 11.7 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 EMR67179.1 - 0.25 10.1 0.0 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DNA_methylase PF00145.17 EMR67180.1 - 1.1e-33 117.0 0.0 1.7e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EMR67180.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 BAH domain Ank_2 PF12796.7 EMR67181.1 - 1.3e-17 64.1 0.2 3.1e-07 30.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR67181.1 - 1.5e-15 57.0 1.0 5.8e-08 32.9 0.0 4.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR67181.1 - 6.6e-12 45.7 0.2 5.6e-08 33.2 0.0 3.8 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EMR67181.1 - 5.8e-11 42.3 1.3 0.033 14.6 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EMR67181.1 - 1.2e-07 31.4 0.1 0.41 11.4 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat GAS PF13851.6 EMR67181.1 - 1.3 8.4 5.4 7.2 5.9 1.4 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EMR67181.1 - 1.4 9.4 4.9 7.1 7.1 0.5 3.4 3 1 0 3 3 3 0 Cell division protein ZapB CFEM PF05730.11 EMR67182.1 - 8.6e-09 35.4 5.6 1.5e-08 34.6 5.6 1.4 1 0 0 1 1 1 1 CFEM domain Isochorismatase PF00857.20 EMR67183.1 - 5.4e-27 95.1 0.2 1.1e-26 94.0 0.2 1.5 1 1 0 1 1 1 1 Isochorismatase family ACC_central PF08326.12 EMR67184.1 - 6.9e-271 900.7 0.0 8.6e-271 900.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EMR67184.1 - 2.1e-179 597.3 0.0 2.8e-179 596.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EMR67184.1 - 1.8e-51 174.6 0.0 3.3e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EMR67184.1 - 1.2e-27 96.6 0.1 4.2e-27 94.9 0.1 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EMR67184.1 - 2.2e-22 79.2 0.0 1.2e-20 73.6 0.0 2.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EMR67184.1 - 2.7e-18 65.6 0.4 7e-18 64.2 0.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme GxGYxYP_N PF16216.5 EMR67184.1 - 0.0065 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Biotin_lipoyl_2 PF13533.6 EMR67184.1 - 0.029 14.2 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EMR67184.1 - 0.066 13.3 0.0 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EMR67184.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus AAA PF00004.29 EMR67187.1 - 1.6e-14 54.5 0.0 4.5e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMR67187.1 - 0.029 14.8 0.0 0.083 13.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EMR67187.1 - 0.18 12.0 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SelR PF01641.18 EMR67188.1 - 3.3e-51 172.4 0.2 3.9e-51 172.2 0.2 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 EMR67188.1 - 0.021 14.9 1.1 3.1 7.9 0.0 2.4 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 EMR67188.1 - 0.028 14.1 0.1 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 EMR67188.1 - 0.08 13.2 0.4 0.2 11.9 0.3 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 EMR67188.1 - 0.14 11.7 1.4 0.6 9.7 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding PP2C PF00481.21 EMR67189.1 - 1.5e-33 116.6 0.0 5.8e-28 98.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C YrzK PF17449.2 EMR67189.1 - 0.0036 17.6 0.1 0.01 16.1 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized YrzK-like PP2C_2 PF13672.6 EMR67189.1 - 0.034 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C DUF382 PF04037.13 EMR67190.1 - 8.3e-60 200.5 1.8 8.3e-60 200.5 1.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EMR67190.1 - 9.9e-18 63.7 5.2 2e-17 62.8 5.2 1.5 1 0 0 1 1 1 1 PSP Snf7 PF03357.21 EMR67192.1 - 3.7e-22 78.7 0.9 3.7e-22 78.7 0.9 1.9 2 0 0 2 2 2 1 Snf7 DUF3484 PF11983.8 EMR67192.1 - 0.066 14.3 1.0 0.12 13.5 0.2 1.8 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch DUF2870 PF11069.8 EMR67192.1 - 0.71 10.3 4.7 6.7 7.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF4470 PF14737.6 EMR67193.1 - 8.4e-13 48.3 0.0 2.2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) ATP-synt_ab PF00006.25 EMR67194.1 - 7e-62 208.8 0.0 1.1e-61 208.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EMR67194.1 - 4.2e-23 81.7 0.7 1.1e-22 80.3 0.3 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 EMR67194.1 - 0.008 16.6 0.1 0.52 10.7 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EMR67194.1 - 0.015 14.5 0.4 0.081 12.1 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 EMR67194.1 - 0.016 15.1 0.5 0.032 14.1 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase T3SS_ATPase_C PF18269.1 EMR67194.1 - 0.023 14.6 0.8 0.12 12.3 0.8 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase_2 PF01637.18 EMR67194.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EMR67194.1 - 0.038 13.4 0.2 0.064 12.6 0.2 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 EMR67194.1 - 0.05 13.9 0.8 0.47 10.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMR67194.1 - 0.053 13.4 0.1 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EMR67194.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EMR67194.1 - 0.11 12.9 0.1 0.39 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF4805 PF16063.5 EMR67195.1 - 0.028 13.7 0.1 0.028 13.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) TPT PF03151.16 EMR67196.1 - 1.4e-56 192.0 7.3 1.7e-56 191.7 7.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EMR67196.1 - 2e-06 28.0 26.2 0.0052 16.9 7.1 3.0 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EMR67196.1 - 0.00047 19.5 11.3 0.0015 17.8 11.3 1.7 1 1 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 EMR67196.1 - 4.3 8.1 11.0 8 7.2 1.1 3.8 4 0 0 4 4 4 0 Small Multidrug Resistance protein CS PF04969.16 EMR67197.1 - 5.3e-07 30.6 0.0 8.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 CS domain Flavin_Reduct PF01613.18 EMR67198.1 - 3.8e-16 59.5 0.1 7.3e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Flavin reductase like domain HD PF01966.22 EMR67198.1 - 0.092 13.0 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 HD domain Oxidored_FMN PF00724.20 EMR67199.1 - 1.8e-30 106.4 0.0 2.9e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.25 EMR67199.1 - 1e-28 100.2 0.0 4.7e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67199.1 - 1.7e-24 86.7 0.1 1.6e-22 80.2 0.1 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67199.1 - 0.013 15.5 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 0 KR domain DUF1776 PF08643.10 EMR67199.1 - 0.032 13.6 0.0 1.5 8.1 0.0 2.5 3 0 0 3 3 3 0 Fungal family of unknown function (DUF1776) Sugar_tr PF00083.24 EMR67201.1 - 2.5e-71 240.9 19.0 1.6e-70 238.2 19.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR67201.1 - 1.3e-10 40.7 34.5 1.5e-05 24.1 12.8 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily HMw1_D2 PF18254.1 EMR67201.1 - 0.0063 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 HMW1 domain 2 MFA1_2 PF17317.2 EMR67201.1 - 0.15 11.8 0.6 0.44 10.3 0.6 1.8 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 HPP PF04982.13 EMR67201.1 - 0.94 9.7 12.3 0.63 10.2 1.1 3.1 3 1 0 3 3 3 0 HPP family SIR2 PF02146.17 EMR67202.1 - 1.4e-24 87.0 0.1 1.3e-14 54.5 0.1 2.8 2 1 0 2 2 2 2 Sir2 family DZR PF12773.7 EMR67203.1 - 2.5 8.2 8.6 3 8.0 0.6 3.4 3 0 0 3 3 3 0 Double zinc ribbon zf-UBR PF02207.20 EMR67203.1 - 4.7 7.4 7.9 0.17 12.1 0.5 2.3 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) adh_short PF00106.25 EMR67204.1 - 1.2e-21 77.1 0.0 1.3e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67204.1 - 3.2e-14 53.1 0.0 1.2e-11 44.6 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67204.1 - 1.2e-05 25.4 0.2 1.2e-05 25.4 0.2 1.6 2 0 0 2 2 2 1 KR domain ThiF PF00899.21 EMR67204.1 - 0.0093 15.3 0.5 0.016 14.6 0.1 1.5 1 1 1 2 2 2 1 ThiF family Chitin_bind_4 PF00379.23 EMR67204.1 - 0.09 13.3 0.2 0.21 12.2 0.2 1.6 1 0 0 1 1 1 0 Insect cuticle protein Shikimate_DH PF01488.20 EMR67204.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EMR67205.1 - 8.5e-11 41.7 1.3 7.8e-07 28.7 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EMR67205.1 - 2.8e-09 36.6 0.3 0.00053 19.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR67205.1 - 5.4e-05 22.4 0.1 9e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMR67205.1 - 7.9e-05 21.5 0.1 0.0052 15.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EMR67205.1 - 8.2e-05 22.8 0.3 0.00024 21.3 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EMR67205.1 - 0.00028 20.1 0.0 0.0006 19.0 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMR67205.1 - 0.00097 18.5 1.4 0.029 13.6 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR67205.1 - 0.0046 17.5 0.2 0.14 12.7 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR67205.1 - 0.0068 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EMR67205.1 - 0.0082 15.8 0.1 0.061 12.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMR67205.1 - 0.077 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EMR67205.1 - 0.19 10.7 0.8 2.3 7.2 0.0 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein Aldo_ket_red PF00248.21 EMR67206.1 - 1.8e-46 158.7 0.0 2.1e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Macro PF01661.21 EMR67208.1 - 2.4e-39 134.0 0.0 4.8e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Macro domain Ank_2 PF12796.7 EMR67209.1 - 4.1e-26 91.4 0.1 4.9e-10 39.9 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR67209.1 - 2e-22 79.3 3.9 2.9e-05 24.5 0.0 6.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EMR67209.1 - 1.3e-15 57.1 1.0 0.044 14.2 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EMR67209.1 - 3.2e-11 42.4 3.0 0.11 13.2 0.0 7.2 8 1 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 EMR67209.1 - 3.6e-10 39.9 1.2 0.074 13.4 0.0 6.5 6 2 1 7 7 7 4 Ankyrin repeats (many copies) ZZ PF00569.17 EMR67209.1 - 0.00019 21.2 8.5 0.00034 20.4 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 EMR67209.1 - 0.006 16.9 9.2 0.012 16.0 9.2 1.4 1 0 0 1 1 1 1 C1 domain SOBP PF15279.6 EMR67210.1 - 0.1 13.2 0.9 0.21 12.2 0.0 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein Zip PF02535.22 EMR67211.1 - 7.6e-25 87.8 8.3 2.2e-18 66.6 3.8 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Mito_carr PF00153.27 EMR67213.1 - 1e-28 99.1 0.2 4.6e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein SCA7 PF08313.12 EMR67214.1 - 7.5e-32 109.0 0.2 2.1e-31 107.6 0.2 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.14 EMR67214.1 - 0.25 9.6 11.4 0.33 9.2 11.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 EMR67214.1 - 0.52 9.6 5.0 0.42 10.0 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) SAPS PF04499.15 EMR67214.1 - 4.9 5.8 4.9 6.2 5.5 4.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RES PF08808.11 EMR67215.1 - 0.036 14.0 0.6 0.073 12.9 0.2 1.6 1 1 1 2 2 2 0 RES domain MFS_1 PF07690.16 EMR67216.1 - 2.5e-17 62.8 11.6 2.5e-17 62.8 11.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Iso_dh PF00180.20 EMR67218.1 - 1.3e-86 290.9 0.0 1.5e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_1 PF00561.20 EMR67219.1 - 1e-22 81.1 0.1 1.1e-22 80.9 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR67219.1 - 4.7e-20 73.1 3.1 5.7e-20 72.9 3.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR67219.1 - 1.6e-11 43.9 0.0 3.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMR67219.1 - 8.8e-06 26.0 0.0 5.9e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase PF07224.11 EMR67219.1 - 0.0049 15.9 0.0 0.022 13.8 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 EMR67219.1 - 0.023 13.4 0.0 0.057 12.1 0.0 1.6 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) baeRF_family10 PF18854.1 EMR67219.1 - 0.025 14.8 0.1 0.26 11.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Ndr PF03096.14 EMR67219.1 - 0.028 13.1 0.0 0.23 10.1 0.0 2.1 2 0 0 2 2 2 0 Ndr family Chlorophyllase2 PF12740.7 EMR67219.1 - 0.1 11.5 0.0 0.31 9.9 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Pkinase PF00069.25 EMR67220.1 - 5.2e-68 229.3 0.0 9.8e-68 228.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR67220.1 - 1.6e-36 125.9 0.0 4.2e-36 124.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR67220.1 - 2.6e-06 27.0 0.0 7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMR67220.1 - 0.0038 17.2 0.1 0.017 15.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMR67220.1 - 0.011 14.6 0.0 0.023 13.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EMR67220.1 - 0.042 12.9 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2855 PF11017.8 EMR67221.1 - 1.7e-95 320.6 0.2 1.9e-95 320.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) zf-C2H2_4 PF13894.6 EMR67222.1 - 7.4e-18 63.7 28.7 0.022 15.6 0.2 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMR67222.1 - 1.6e-11 44.2 29.0 0.0054 17.0 0.5 7.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EMR67222.1 - 1.7e-11 44.3 28.6 0.022 15.1 0.9 6.6 2 2 5 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EMR67222.1 - 1.2e-10 41.2 37.1 0.22 12.1 0.1 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-met PF12874.7 EMR67222.1 - 3.4e-09 36.8 29.3 0.004 17.5 0.4 7.2 7 1 0 7 7 7 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EMR67222.1 - 1.8e-07 31.3 25.7 0.07 13.6 0.3 7.5 7 0 0 7 7 7 3 Zinc-finger double domain Zn-C2H2_12 PF18112.1 EMR67222.1 - 0.022 15.2 4.3 0.33 11.5 0.1 3.8 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HC_2 PF13913.6 EMR67222.1 - 0.17 11.8 21.0 2.1 8.4 0.7 5.9 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EMR67222.1 - 0.18 11.9 30.8 0.63 10.1 0.6 7.8 8 0 0 8 8 8 0 C2H2-type zinc finger zf-FCS PF06467.14 EMR67222.1 - 0.18 11.8 12.0 8.1 6.5 0.1 5.1 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.12 EMR67222.1 - 0.18 12.1 0.3 0.18 12.1 0.3 4.7 3 2 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 EMR67222.1 - 0.5 10.2 7.4 7.5 6.5 0.0 4.3 4 1 1 5 5 5 0 Rad50 zinc hook motif AKAP95 PF04988.12 EMR67222.1 - 1 9.5 15.1 0.25 11.6 0.6 4.1 2 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_9 PF16293.5 EMR67222.1 - 1.2 9.0 16.2 3.2 7.7 0.1 5.5 4 2 3 7 7 7 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_9 PF14369.6 EMR67222.1 - 1.9 8.8 0.0 1.9 8.8 0.0 5.3 6 1 1 7 7 7 0 zinc-ribbon zf-LYAR PF08790.11 EMR67222.1 - 4.7 7.2 0.0 4.7 7.2 0.0 5.3 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 EMR67222.1 - 4.9 7.3 16.3 48 4.2 0.0 5.6 6 0 0 6 6 5 0 Uncharacterized protein conserved in bacteria (DUF2256) adh_short PF00106.25 EMR67223.1 - 2.1e-06 27.3 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67223.1 - 1.7e-05 24.5 0.0 1.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EMR67223.1 - 0.0039 16.8 0.0 0.014 14.9 0.0 1.8 1 1 1 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EMR67223.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain CoA_binding_2 PF13380.6 EMR67223.1 - 0.042 14.3 0.1 0.085 13.4 0.1 1.5 1 1 0 1 1 1 0 CoA binding domain Fungal_trans PF04082.18 EMR67224.1 - 3.8e-06 26.1 0.0 6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1772 PF08592.11 EMR67225.1 - 3.2e-32 111.7 8.4 3.9e-32 111.4 8.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Lactamase_B PF00753.27 EMR67226.1 - 1.6e-17 64.1 6.9 1.1e-16 61.5 6.9 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMR67226.1 - 6.8e-07 29.0 1.1 1.3e-06 28.1 1.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 EMR67226.1 - 0.05 13.6 0.2 0.5 10.4 0.0 2.5 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain DUF3198 PF11433.8 EMR67227.1 - 0.014 15.3 1.1 12 5.9 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3198) GlcNAc PF11397.8 EMR67227.1 - 0.35 10.3 5.6 26 4.1 0.1 4.2 1 1 4 5 5 5 0 Glycosyltransferase (GlcNAc) XLF PF09302.11 EMR67228.1 - 7.9e-51 172.8 0.0 1.6e-50 171.7 0.0 1.5 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component HTH_Tnp_ISL3 PF13542.6 EMR67229.1 - 0.0067 15.8 0.0 0.084 12.3 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 EMR67229.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 EMR67229.1 - 0.11 12.6 0.0 0.62 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix adh_short PF00106.25 EMR67230.1 - 2.7e-27 95.5 0.0 6.5e-27 94.3 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67230.1 - 1.4e-13 51.0 0.0 2.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 EMR67230.1 - 7.6e-13 48.1 45.5 1e-11 44.4 45.1 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR67230.1 - 8.3e-09 34.4 16.2 1.3e-08 33.7 16.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) KR PF08659.10 EMR67230.1 - 1e-08 35.3 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR67230.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FIVAR PF07554.13 EMR67230.1 - 0.13 13.0 0.1 0.3 11.9 0.1 1.5 1 0 0 1 1 1 0 FIVAR domain SPC25 PF06703.11 EMR67230.1 - 1.4 8.7 3.3 2.2 8.1 1.9 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) GST_N PF02798.20 EMR67231.1 - 3.8e-13 49.6 0.0 6.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR67231.1 - 1.3e-11 44.6 0.0 2.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR67231.1 - 1.7e-05 24.8 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR67231.1 - 3e-05 24.4 0.0 5.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR67231.1 - 5e-05 23.4 0.1 9.2e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR67231.1 - 0.00049 20.4 0.0 0.0012 19.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain adh_short PF00106.25 EMR67232.1 - 1.5e-26 93.1 0.0 3.5e-21 75.6 0.2 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67232.1 - 2.4e-12 46.9 0.3 2.2e-11 43.8 0.6 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67232.1 - 2.3e-11 44.0 0.2 6.4e-11 42.5 0.3 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 EMR67233.1 - 9.2e-47 159.6 0.8 1.4e-45 155.7 0.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR67233.1 - 5.4e-43 146.7 0.2 6.7e-43 146.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR67233.1 - 1.6e-05 24.9 0.1 4.4e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 EMR67233.1 - 0.037 13.4 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TrmE_N PF10396.9 EMR67233.1 - 0.086 13.2 0.0 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus ketoacyl-synt PF00109.26 EMR67234.1 - 1.3e-73 247.8 0.0 1.2e-72 244.6 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EMR67234.1 - 5.6e-41 141.1 0.9 8.5e-41 140.5 0.3 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR67234.1 - 4.6e-33 113.7 2.2 1.8e-32 111.9 2.2 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 EMR67234.1 - 2.3e-21 76.6 0.7 6.9e-12 45.6 0.0 3.7 2 1 1 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 EMR67234.1 - 5.1e-12 46.0 0.4 1.5e-11 44.5 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EMR67234.1 - 1.3e-08 35.3 0.0 1.6e-07 31.8 0.0 2.8 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EMR67234.1 - 1.3e-08 34.4 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EMR67234.1 - 3.6e-05 23.2 0.1 0.00011 21.7 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 EMR67234.1 - 0.21 12.2 5.5 0.045 14.3 0.6 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family GMC_oxred_C PF05199.13 EMR67235.1 - 3.4e-38 131.4 0.1 5.1e-38 130.8 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR67235.1 - 1.1e-35 123.5 0.0 2.3e-35 122.4 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_10 PF13460.6 EMR67236.1 - 1e-15 58.1 0.0 1.4e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR67236.1 - 5.4e-07 29.4 0.0 7.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMR67236.1 - 0.0073 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EMR67236.1 - 0.02 13.9 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMR67236.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 EMR67238.1 - 3.7e-51 174.3 0.0 4.3e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_34 PF13601.6 EMR67238.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain GMC_oxred_C PF05199.13 EMR67239.1 - 2.1e-30 106.1 0.0 3.5e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR67239.1 - 2.7e-19 69.7 0.0 3.5e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Questin_oxidase PF14027.6 EMR67240.1 - 7.7e-86 288.7 0.0 9.5e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Scytalone_dh PF02982.14 EMR67241.1 - 2.3e-69 232.2 2.0 2.6e-69 232.1 2.0 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EMR67241.1 - 2.5e-08 34.1 0.8 3.1e-08 33.8 0.8 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4304 PF14137.6 EMR67241.1 - 0.039 14.1 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) SnoaL_3 PF13474.6 EMR67241.1 - 0.1 12.9 1.9 1.3 9.3 1.9 2.1 1 1 0 1 1 1 0 SnoaL-like domain RNA_pol_3_Rpc31 PF11705.8 EMR67242.1 - 1.3e-42 146.6 27.8 1.1e-39 137.0 27.8 2.2 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CDC27 PF09507.10 EMR67242.1 - 7 5.9 8.9 8.9 5.6 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA PF00004.29 EMR67243.1 - 3e-13 50.3 0.0 1.3e-12 48.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMR67243.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMR67243.1 - 2 8.7 4.6 13 6.0 0.4 3.4 2 1 1 3 3 3 0 AAA domain SlyX PF04102.12 EMR67243.1 - 3.7 8.2 9.6 1.3 9.7 5.7 2.2 2 0 0 2 2 2 0 SlyX Proteasom_PSMB PF10508.9 EMR67244.1 - 0.002 16.7 0.5 0.009 14.6 0.0 1.9 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Fungal_trans PF04082.18 EMR67245.1 - 8.2e-17 61.1 0.2 1.2e-16 60.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-G-binding_N PF07299.11 EMR67246.1 - 0.03 14.9 0.8 0.086 13.4 0.3 1.9 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal CbiG_N PF11760.8 EMR67246.1 - 0.04 13.9 1.3 0.054 13.5 0.2 1.8 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal MFS_1 PF07690.16 EMR67247.1 - 1.1e-38 133.0 27.1 2.5e-34 118.8 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 EMR67247.1 - 0.49 10.6 2.3 0.56 10.4 0.0 2.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit Ion_trans PF00520.31 EMR67248.1 - 5.2e-05 22.6 27.9 0.0014 17.9 27.9 2.2 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EMR67248.1 - 8.8e-05 21.4 22.0 0.00053 18.8 22.0 2.0 1 1 0 1 1 1 1 Polycystin cation channel Sec7 PF01369.20 EMR67249.1 - 1.6e-70 236.5 0.8 3.6e-70 235.4 0.1 2.0 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 EMR67249.1 - 1.1e-32 111.7 11.6 2e-31 107.7 0.0 6.2 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 EMR67249.1 - 1.1e-27 96.9 4.3 8.5e-13 48.5 0.0 3.8 2 1 1 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EMR67249.1 - 2.2e-21 76.3 2.2 6.4e-19 68.3 0.3 3.4 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 2-oxoacid_dh PF00198.23 EMR67250.1 - 8.7e-76 254.4 0.3 1.1e-75 254.1 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMR67250.1 - 4.4e-19 68.1 2.2 1.2e-18 66.7 2.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EMR67250.1 - 3.4e-11 43.3 1.0 9.8e-11 41.8 1.0 1.8 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 EMR67250.1 - 0.026 15.0 0.1 0.062 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Fungal_trans_2 PF11951.8 EMR67251.1 - 1.4e-09 37.3 1.2 1.6e-08 33.7 1.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain MOSC_N PF03476.16 EMR67252.1 - 9.8e-14 51.3 0.0 1.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EMR67252.1 - 1.3e-10 41.4 0.0 2.3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain NOT2_3_5 PF04153.18 EMR67253.1 - 1.4e-27 96.3 2.8 2.2e-27 95.7 2.8 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family OSR1_C PF12202.8 EMR67253.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain Mob1_phocein PF03637.17 EMR67254.1 - 1.6e-21 77.1 0.0 2.6e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 EMR67254.1 - 0.2 12.0 3.8 0.55 10.5 3.8 1.8 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases AAA_2 PF07724.14 EMR67255.1 - 3.4e-33 115.2 0.1 3.3e-29 102.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EMR67255.1 - 1.1e-10 42.1 0.0 2.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EMR67255.1 - 4.9e-08 32.9 0.1 1.1e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EMR67255.1 - 2.8e-05 24.1 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMR67255.1 - 0.0062 16.9 0.1 0.026 14.9 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain MCM PF00493.23 EMR67255.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 EMR67255.1 - 0.026 14.8 1.2 0.29 11.4 0.2 2.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMR67255.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ORC5_C PF14630.6 EMR67256.1 - 1.6e-77 260.9 0.0 2.2e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EMR67256.1 - 5.8e-13 49.6 0.2 1.9e-12 47.9 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR67256.1 - 0.003 17.8 0.0 0.0097 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EMR67256.1 - 0.027 14.4 0.0 0.16 11.9 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Alpha-amylase_C PF02806.18 EMR67258.1 - 5.6e-28 97.3 0.1 1.5e-27 95.9 0.1 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EMR67258.1 - 4.9e-19 68.5 0.0 2e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EMR67258.1 - 8.2e-17 61.8 0.2 1.5e-12 47.7 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Cellulase PF00150.18 EMR67258.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.6 EMR67258.1 - 0.19 10.8 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain eIF-3c_N PF05470.12 EMR67259.1 - 3.4e-176 587.1 19.9 9.6e-147 489.8 1.9 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EMR67259.1 - 1.6e-13 51.0 0.1 2.6e-12 47.2 0.0 2.8 2 0 0 2 2 2 1 PCI domain CDC45 PF02724.14 EMR67259.1 - 0.4 8.9 23.0 0.64 8.2 23.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 EMR67259.1 - 3.4 6.0 14.7 5 5.5 14.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 AAA_12 PF13087.6 EMR67260.1 - 2.5e-25 89.3 0.0 1.1e-24 87.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EMR67260.1 - 5.8e-07 29.6 0.0 1.5e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EMR67260.1 - 0.0058 16.4 0.2 1.1 8.9 0.1 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EMR67260.1 - 0.15 11.7 0.0 1.6 8.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain FRB_dom PF08771.11 EMR67261.1 - 0.00025 21.4 0.5 0.0003 21.1 0.5 1.1 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain Uds1 PF15456.6 EMR67261.1 - 0.041 14.0 2.5 0.05 13.8 2.5 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Tfb2 PF03849.14 EMR67261.1 - 0.16 10.9 0.8 0.2 10.6 0.8 1.0 1 0 0 1 1 1 0 Transcription factor Tfb2 NmrA PF05368.13 EMR67262.1 - 1.9e-34 119.2 0.0 2.6e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR67262.1 - 6.5e-12 45.7 0.0 8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR67262.1 - 0.00043 19.8 0.0 0.00064 19.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR67262.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EMR67262.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 EMR67262.1 - 0.24 10.4 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HET PF06985.11 EMR67263.1 - 2.3e-12 47.5 3.8 3.1e-09 37.3 0.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4857 PF16149.5 EMR67263.1 - 0.2 10.8 0.0 0.67 9.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4857) Pet100 PF09803.9 EMR67264.1 - 1.3e-20 73.6 0.2 1.6e-20 73.4 0.2 1.1 1 0 0 1 1 1 1 Pet100 FAD_binding_4 PF01565.23 EMR67265.1 - 4.7e-24 84.7 0.5 9.1e-24 83.8 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain DUF1772 PF08592.11 EMR67266.1 - 6.8e-23 81.5 0.4 8.8e-23 81.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Hemerythrin PF01814.23 EMR67267.1 - 2.9e-14 53.8 0.2 4e-14 53.4 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HEAT_2 PF13646.6 EMR67269.1 - 5.2e-11 42.8 4.5 0.61 10.5 0.0 7.4 6 1 1 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EMR67269.1 - 7.6e-08 32.9 0.0 0.056 14.0 0.0 6.1 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EMR67269.1 - 7.7e-08 32.0 17.5 0.17 12.3 0.1 9.9 10 0 0 10 10 10 3 HEAT repeat CLASP_N PF12348.8 EMR67269.1 - 6e-06 26.0 4.7 0.71 9.4 0.0 5.4 4 1 1 5 5 5 2 CLASP N terminal V-ATPase_H_C PF11698.8 EMR67269.1 - 0.0016 18.6 0.4 0.13 12.4 0.0 3.8 4 0 0 4 4 4 1 V-ATPase subunit H HEAT_EZ PF13513.6 EMR67269.1 - 0.059 13.9 14.1 16 6.2 0.0 7.2 6 0 0 6 6 6 0 HEAT-like repeat Adaptin_N PF01602.20 EMR67269.1 - 0.071 11.7 4.1 9 4.7 0.0 4.8 5 0 0 5 5 5 0 Adaptin N terminal region FAD_binding_3 PF01494.19 EMR67270.1 - 7.6e-10 38.6 0.7 2.1e-08 33.8 0.7 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR67270.1 - 0.00012 21.4 0.1 0.00026 20.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR67270.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR67270.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Transcrip_reg PF01709.20 EMR67272.1 - 2.1e-53 181.2 0.0 2.6e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Motile_Sperm PF00635.26 EMR67273.1 - 8.5e-19 67.4 0.1 1.6e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.8 EMR67273.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase FA_desaturase PF00487.24 EMR67274.1 - 6e-28 98.4 13.9 9.3e-28 97.7 13.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EMR67274.1 - 2e-18 65.5 0.4 4.8e-18 64.3 0.4 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DUF2536 PF10750.9 EMR67274.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) Na_Ca_ex PF01699.24 EMR67275.1 - 4.2e-09 36.5 0.9 4.8e-09 36.3 0.9 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Cnd2 PF05786.14 EMR67276.1 - 1.1e-282 940.3 0.2 8.5e-194 646.4 0.0 2.0 1 1 1 2 2 2 2 Condensin complex subunit 2 CNDH2_N PF06278.11 EMR67276.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Gag_p15 PF08723.10 EMR67276.1 - 0.15 12.3 0.2 0.57 10.4 0.1 1.9 2 0 0 2 2 2 0 Gag protein p15 SAM_1 PF00536.30 EMR67277.1 - 6.5e-09 36.1 0.4 1.2e-08 35.3 0.0 1.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box PF00505.19 EMR67277.1 - 2.7e-07 30.9 10.0 6.8e-07 29.6 2.2 2.6 2 1 1 3 3 3 2 HMG (high mobility group) box SAM_2 PF07647.17 EMR67277.1 - 1.2e-06 28.5 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 EMR67277.1 - 1.4e-05 25.6 1.8 1.4e-05 25.6 1.8 2.6 2 1 1 3 3 3 1 HMG-box domain YpsA PF06908.11 EMR67277.1 - 0.077 13.0 1.4 0.12 12.4 1.4 1.2 1 0 0 1 1 1 0 YspA SLOG family WYL_3 PF18488.1 EMR67277.1 - 0.093 13.1 3.7 0.18 12.2 3.0 1.8 2 0 0 2 2 2 0 WYL domain DUF3811 PF11656.8 EMR67277.1 - 0.21 12.0 4.3 0.38 11.2 4.0 1.5 2 0 0 2 2 2 0 YjbD family (DUF3811) PMM PF03332.13 EMR67278.1 - 3e-101 337.8 0.1 3.4e-101 337.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EMR67278.1 - 0.00025 20.9 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMR67278.1 - 0.059 13.8 0.0 5.5 7.3 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase AAA_lid_7 PF17867.1 EMR67279.1 - 0.068 13.4 0.0 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 Midasin AAA lid domain Transformer PF06495.11 EMR67279.1 - 0.36 10.9 1.7 0.44 10.6 0.3 1.8 2 0 0 2 2 2 0 Fruit fly transformer protein Pex14_N PF04695.13 EMR67279.1 - 0.51 11.0 7.2 0.67 10.6 4.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3446 PF11928.8 EMR67279.1 - 2.6 8.4 8.2 4.5 7.6 4.0 3.1 3 0 0 3 3 3 0 Early growth response N-terminal domain Glyco_hydro_92 PF07971.12 EMR67280.1 - 2.4e-24 86.1 0.0 2.7e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ptaRNA1_toxin PF12703.7 EMR67281.1 - 0.094 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system RhgB_N PF09284.10 EMR67284.1 - 1.5e-87 293.3 1.4 2.3e-87 292.7 1.4 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EMR67284.1 - 1.3e-33 116.2 0.5 1.7e-32 112.6 0.1 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EMR67284.1 - 3.2e-16 58.9 2.1 1.2e-15 57.0 2.1 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EMR67284.1 - 0.005 17.1 0.4 0.005 17.1 0.4 2.6 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Cupin_5 PF06172.11 EMR67284.1 - 0.029 14.5 0.1 0.061 13.5 0.1 1.5 1 0 0 1 1 1 0 Cupin superfamily (DUF985) F-box-like PF12937.7 EMR67285.1 - 9.3e-09 35.1 0.0 5.7e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EMR67285.1 - 1.9e-07 30.8 0.5 6.1e-07 29.2 0.0 2.1 2 1 0 2 2 2 1 F-box domain Phage_T4_Gp30_7 PF06919.11 EMR67285.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage Gp30.7 protein Vac7 PF12751.7 EMR67286.1 - 2.2e-86 290.7 19.5 4e-66 224.0 11.5 2.9 2 1 1 3 3 3 2 Vacuolar segregation subunit 7 Trimer_CC PF08954.11 EMR67288.1 - 0.0034 16.9 0.2 0.018 14.6 0.2 2.3 1 0 0 1 1 1 1 Trimerisation motif SUIM_assoc PF16619.5 EMR67288.1 - 0.37 10.9 5.3 1.3 9.1 5.3 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Amidohydro_2 PF04909.14 EMR67289.1 - 7.3e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Catalase_C PF18011.1 EMR67289.1 - 0.062 12.9 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 C-terminal domain found in long catalases Ribosomal_L7Ae PF01248.26 EMR67290.1 - 2e-24 85.1 0.0 2.3e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 EMR67291.1 - 3.3e-44 150.1 0.1 4.5e-44 149.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SKG6 PF08693.10 EMR67292.1 - 2.1e-05 23.8 0.5 4e-05 22.9 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF5134 PF17197.4 EMR67292.1 - 0.017 15.0 0.2 0.026 14.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) VSP PF03302.13 EMR67292.1 - 0.025 13.4 0.3 0.034 13.0 0.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2207 PF09972.9 EMR67292.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AAA_2 PF07724.14 EMR67293.1 - 9.1e-06 25.9 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 EMR67293.1 - 0.011 15.8 0.0 0.035 14.1 0.0 2.0 1 1 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EMR67293.1 - 0.098 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMR67293.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TFIIA PF03153.13 EMR67294.1 - 0.74 9.8 33.5 1.9 8.4 19.1 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 EMR67294.1 - 1.7 8.8 34.5 0.042 13.9 9.5 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DDE_Tnp_1_2 PF13586.6 EMR67294.1 - 6.8 7.1 6.1 1.9 8.9 0.1 2.3 2 0 0 2 2 2 0 Transposase DDE domain Suf PF05843.14 EMR67294.1 - 8.2 6.3 15.6 3 7.7 7.7 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3450 PF11932.8 EMR67296.1 - 0.025 13.9 24.4 0.054 12.8 16.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FapA PF03961.13 EMR67296.1 - 0.12 11.0 10.5 0.031 12.9 6.3 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Bacillus_HBL PF05791.11 EMR67296.1 - 0.19 11.5 5.2 0.45 10.3 5.2 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 EMR67296.1 - 0.51 10.5 22.5 0.59 10.3 8.5 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Tweety PF04906.13 EMR67296.1 - 0.86 8.2 3.1 1.3 7.6 3.1 1.2 1 0 0 1 1 1 0 Tweety DUF87 PF01935.17 EMR67296.1 - 0.92 9.6 7.9 29 4.7 6.7 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Herpes_UL6 PF01763.16 EMR67296.1 - 2.4 6.6 12.3 2.2 6.7 9.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like V_ATPase_I PF01496.19 EMR67296.1 - 4.1 5.2 14.9 11 3.8 0.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 EMR67296.1 - 6 5.6 16.3 12 4.6 11.5 2.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain CwfJ_C_2 PF04676.14 EMR67297.1 - 8.5e-30 103.6 0.1 8.5e-30 103.6 0.1 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EMR67297.1 - 4.2e-29 100.9 0.0 7.6e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 BTB PF00651.31 EMR67299.1 - 5.5e-08 33.0 0.0 1.6e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 EMR67299.1 - 0.068 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Peptidase_S24 PF00717.23 EMR67300.1 - 9.3e-07 28.7 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like TFIIB PF00382.19 EMR67301.1 - 1.8e-27 95.2 0.0 1.4e-18 66.7 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EMR67301.1 - 1.6e-23 83.0 0.7 1.6e-23 83.0 0.7 3.6 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 EMR67301.1 - 0.018 14.8 0.2 1.7 8.4 0.0 2.6 3 0 0 3 3 3 0 Cyclin, N-terminal domain Sulfotransfer_3 PF13469.6 EMR67301.1 - 0.086 13.2 0.4 11 6.4 0.2 3.0 3 0 0 3 3 3 0 Sulfotransferase family Arginosuc_synth PF00764.19 EMR67303.1 - 1.3e-132 442.8 0.0 1.6e-132 442.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase SRR1 PF07985.12 EMR67305.1 - 1.5e-10 41.0 0.0 2.6e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 SRR1 Tissue_fac PF01108.17 EMR67305.1 - 0.076 12.9 2.4 0.091 12.6 0.3 2.1 2 1 0 2 2 2 0 Tissue factor Pyrid_ox_like PF16242.5 EMR67307.1 - 1.3e-16 60.5 0.0 2.3e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EMR67307.1 - 2.2e-05 24.6 0.0 8.2e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ThiC-associated PF13667.6 EMR67307.1 - 0.0034 17.2 0.5 0.059 13.2 0.1 2.3 2 0 0 2 2 2 1 ThiC-associated domain ketoacyl-synt PF00109.26 EMR67308.1 - 6.4e-84 281.5 0.5 1.8e-83 280.0 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EMR67308.1 - 6.3e-59 198.9 0.0 1.5e-58 197.7 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EMR67308.1 - 4.2e-43 148.1 0.5 7.4e-39 134.1 0.2 3.3 2 1 1 3 3 3 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR67308.1 - 3.4e-39 133.5 2.3 7.8e-39 132.4 1.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR67308.1 - 2.2e-12 47.4 0.0 5.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EMR67308.1 - 2.8e-10 39.9 0.0 0.00028 20.2 0.0 2.3 2 0 0 2 2 2 2 Polyketide synthase dehydratase PP-binding PF00550.25 EMR67308.1 - 4.2e-08 33.4 0.0 1.1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EMR67308.1 - 5.4e-05 22.7 3.2 8e-05 22.1 0.2 2.7 4 0 0 4 4 4 1 Thiolase, N-terminal domain adh_short PF00106.25 EMR67308.1 - 7.1e-05 22.3 0.0 0.00026 20.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EMR67309.1 - 5.4e-10 39.1 0.3 9.1e-06 25.3 0.0 2.9 2 1 1 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR67309.1 - 7.8e-06 25.5 0.2 2.2e-05 24.0 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMR67309.1 - 0.00021 21.3 0.0 0.59 10.0 0.0 2.5 2 1 0 3 3 3 2 NAD(P)H-binding NmrA PF05368.13 EMR67309.1 - 0.0065 16.1 0.0 0.069 12.7 0.0 2.1 1 1 1 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 EMR67309.1 - 0.0076 15.3 0.2 0.54 9.2 0.1 2.3 1 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMR67309.1 - 0.018 14.2 0.1 0.95 8.6 0.0 2.2 1 1 1 2 2 2 0 Male sterility protein adh_short PF00106.25 EMR67309.1 - 0.059 12.8 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase NepR PF18557.1 EMR67310.1 - 0.0041 16.7 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Anti-sigma factor NepR Cupin_2 PF07883.11 EMR67310.1 - 0.0051 16.5 0.4 0.018 14.7 0.2 1.9 2 0 0 2 2 2 1 Cupin domain Arginase PF00491.21 EMR67311.1 - 4e-87 292.3 0.0 5.5e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EMR67311.1 - 0.043 14.0 0.1 0.068 13.4 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain Nup192 PF11894.8 EMR67312.1 - 0 1277.3 2.4 2e-235 784.4 0.0 2.0 1 1 1 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 Voltage_CLC PF00654.20 EMR67313.1 - 6e-32 111.3 12.8 8e-32 110.9 12.8 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel LacI PF00356.21 EMR67313.1 - 0.2 11.5 1.8 0.42 10.5 1.8 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family His_Phos_2 PF00328.22 EMR67314.1 - 2.5e-16 60.0 0.0 1.2e-12 47.9 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RTA1 PF04479.13 EMR67315.1 - 2.4e-43 148.2 2.5 2.4e-43 148.2 2.5 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF4045 PF13254.6 EMR67316.1 - 3.6e-37 129.0 6.7 3.6e-37 129.0 6.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EMR67316.1 - 1e-08 34.9 0.0 0.00012 22.0 0.0 3.7 3 1 0 3 3 3 2 Gelsolin repeat RRM_1 PF00076.22 EMR67317.1 - 2.1e-34 117.1 0.3 8.4e-11 41.5 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMR67317.1 - 4.8e-15 55.2 0.1 0.0074 16.1 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 EMR67317.1 - 9.4e-09 34.9 2.3 9.4e-09 34.9 2.3 3.7 3 1 0 3 3 3 1 Putative RRM domain DUF4523 PF15023.6 EMR67317.1 - 2.4e-06 27.5 0.0 0.032 14.1 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 EMR67317.1 - 0.00021 21.3 0.5 0.18 11.8 0.2 3.0 3 0 0 3 3 3 2 RNA binding motif RRM_7 PF16367.5 EMR67317.1 - 0.0078 16.3 0.0 18 5.6 0.0 3.6 3 1 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EMR67317.1 - 0.013 15.5 0.1 4.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 EMR67317.1 - 0.017 15.2 1.5 0.18 11.9 0.0 3.0 3 1 1 4 4 4 0 RNA binding domain Ferric_reduct PF01794.19 EMR67318.1 - 3.1e-21 75.8 4.5 5.3e-21 75.0 4.5 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMR67318.1 - 6.8e-17 62.0 0.0 9.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR67318.1 - 9.4e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 EMR67318.1 - 0.012 16.2 7.3 0.18 12.3 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Arf PF00025.21 EMR67319.1 - 2.6e-67 225.6 0.5 3e-67 225.5 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMR67319.1 - 9.5e-13 48.4 0.1 1.3e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EMR67319.1 - 3.7e-12 46.1 0.8 5.4e-07 29.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EMR67319.1 - 5e-12 45.7 0.0 5.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EMR67319.1 - 1.5e-09 37.6 0.0 1.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMR67319.1 - 8.5e-08 32.3 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EMR67319.1 - 2.4e-07 30.4 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EMR67319.1 - 0.0023 17.5 0.0 0.042 13.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 EMR67319.1 - 0.013 15.5 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 EMR67319.1 - 0.11 12.0 0.3 0.27 10.8 0.3 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B ATHILA PF03078.15 EMR67319.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family 6PF2K PF01591.18 EMR67319.1 - 0.17 11.1 0.0 0.39 10.0 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase PI3_PI4_kinase PF00454.27 EMR67320.1 - 5.4e-52 177.1 0.0 1.6e-51 175.6 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EMR67320.1 - 2.8e-07 30.2 0.1 5.9e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 FATC domain PPR_2 PF13041.6 EMR67321.1 - 3.4e-23 81.6 0.0 3.6e-08 33.5 0.0 7.0 6 1 1 7 7 7 4 PPR repeat family PPR_3 PF13812.6 EMR67321.1 - 2.8e-12 46.5 0.0 2.2e-05 24.4 0.0 4.3 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 EMR67321.1 - 9.4e-10 38.1 0.0 0.23 11.8 0.0 6.7 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.7 EMR67321.1 - 9.2e-07 28.5 0.0 0.15 11.8 0.0 5.3 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 EMR67321.1 - 0.017 14.5 0.0 8.3 5.7 0.1 3.0 1 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 EMR67321.1 - 0.023 15.2 1.0 0.34 11.4 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR67321.1 - 0.064 14.1 2.0 24 6.1 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TCTP PF00838.17 EMR67322.1 - 1.3e-65 220.7 0.2 1.5e-65 220.6 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein AA_permease PF00324.21 EMR67323.1 - 3.3e-129 431.6 40.2 4.1e-129 431.3 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR67323.1 - 1.3e-37 129.6 44.3 1.6e-37 129.3 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease GPS2_interact PF15784.5 EMR67324.1 - 0.029 14.8 3.1 0.029 14.8 3.1 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain YqzE PF14038.6 EMR67324.1 - 0.04 13.9 0.2 0.04 13.9 0.2 2.3 2 0 0 2 2 2 0 YqzE-like protein CDC45 PF02724.14 EMR67324.1 - 1.5 7.0 7.4 2.9 6.1 6.9 1.5 1 1 1 2 2 2 0 CDC45-like protein FA_hydroxylase PF04116.13 EMR67325.1 - 5.7e-17 62.3 11.4 1.4e-16 61.1 9.0 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Mis12 PF05859.12 EMR67327.1 - 2.7e-44 150.5 0.0 5.1e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein Nucleo_P87 PF07267.11 EMR67327.1 - 0.033 13.0 3.7 0.045 12.6 3.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CCDC106 PF15794.5 EMR67327.1 - 0.47 10.1 6.7 0.86 9.3 6.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FAM176 PF14851.6 EMR67327.1 - 1.9 8.1 4.3 5.5 6.6 4.3 1.7 1 0 0 1 1 1 0 FAM176 family PCI PF01399.27 EMR67328.1 - 1.1e-18 67.6 0.1 4.9e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 PCI domain DUF4423 PF14394.6 EMR67328.1 - 0.0027 17.5 0.1 1.3 8.7 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4423) TPR_2 PF07719.17 EMR67328.1 - 0.016 15.3 2.6 0.18 12.0 0.0 4.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 EMR67328.1 - 0.019 14.3 0.6 0.081 12.2 0.2 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase TPR_1 PF00515.28 EMR67328.1 - 0.019 14.8 0.1 0.57 10.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMR67328.1 - 0.02 14.9 1.6 0.26 11.4 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMR67328.1 - 0.08 13.2 0.1 2.3 8.6 0.0 3.1 4 1 0 4 4 4 0 Tetratricopeptide repeat XLF PF09302.11 EMR67328.1 - 0.097 12.8 1.1 0.32 11.1 0.3 2.1 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component GSDH PF07995.11 EMR67329.1 - 6.7e-117 390.5 0.1 7.8e-117 390.3 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 EMR67329.1 - 0.002 18.1 1.4 4 8.0 0.0 4.0 3 0 0 3 3 3 2 Two component regulator propeller NHL PF01436.21 EMR67329.1 - 0.054 13.6 0.0 0.45 10.6 0.0 2.6 2 0 0 2 2 2 0 NHL repeat NUDIX PF00293.28 EMR67330.1 - 4.3e-16 59.1 0.1 6.3e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Med17 PF10156.9 EMR67331.1 - 6.6e-69 232.8 0.0 9.5e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Methyltransf_2 PF00891.18 EMR67332.1 - 6.8e-20 71.3 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain THDPS_N_2 PF14805.6 EMR67333.1 - 0.6 10.4 3.2 1.5 9.1 0.5 2.5 2 1 1 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Menin PF05053.13 EMR67333.1 - 2.2 6.5 10.4 3.7 5.8 10.4 1.4 1 0 0 1 1 1 0 Menin Nuc_N PF14448.6 EMR67333.1 - 6.5 6.7 6.5 5.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Nuclease N terminal GREB1 PF15782.5 EMR67333.1 - 7.6 3.5 13.4 9.5 3.2 13.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PP2C PF00481.21 EMR67334.1 - 4.5e-37 128.1 0.0 9.8e-37 127.0 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EMR67334.1 - 0.033 14.1 0.1 5.2 6.9 0.0 3.1 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) p450 PF00067.22 EMR67335.1 - 1.7e-64 218.3 0.0 2e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EMR67336.1 - 9.6e-48 162.2 2.9 1.3e-47 161.8 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67336.1 - 1.7e-41 142.4 4.2 2.1e-41 142.0 4.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67336.1 - 5.7e-07 29.6 0.8 8.5e-07 29.1 0.8 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMR67336.1 - 0.0024 17.8 0.3 0.004 17.0 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EMR67336.1 - 0.0038 16.7 0.3 0.0057 16.2 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR67336.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EMR67336.1 - 0.013 16.1 0.6 0.041 14.4 0.3 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 EMR67336.1 - 0.015 14.9 0.9 0.028 14.0 0.9 1.5 1 0 0 1 1 1 0 NmrA-like family RTC4 PF14474.6 EMR67336.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 RTC4-like domain THF_DHG_CYH_C PF02882.19 EMR67336.1 - 0.038 13.3 0.4 0.071 12.4 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 EMR67336.1 - 0.05 12.7 0.1 0.082 12.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EMR67336.1 - 0.051 13.0 0.8 0.064 12.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 EMR67336.1 - 0.064 13.3 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F-box-like PF12937.7 EMR67337.1 - 5.7e-06 26.1 0.2 5.7e-06 26.1 0.2 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EMR67337.1 - 8.2e-06 25.6 0.1 8.2e-06 25.6 0.1 2.5 3 0 0 3 3 3 1 F-box domain Aminotran_1_2 PF00155.21 EMR67337.1 - 0.046 12.9 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II Ras PF00071.22 EMR67338.1 - 3.6e-53 179.5 0.0 4.4e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR67338.1 - 1.2e-21 77.1 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR67338.1 - 1.3e-09 37.7 0.0 6.4e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMR67338.1 - 4.6e-05 22.9 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EMR67338.1 - 0.0025 17.0 0.0 0.0045 16.2 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 EMR67338.1 - 0.0047 16.4 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EMR67338.1 - 0.0068 16.5 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR67338.1 - 0.016 15.2 0.0 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EMR67338.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EMR67338.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF2207 PF09972.9 EMR67339.1 - 0.099 11.4 0.5 0.11 11.2 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CoxIIa PF08113.11 EMR67339.1 - 7.5 6.5 9.7 5.1 7.0 3.2 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family CWC25 PF12542.8 EMR67340.1 - 9.6e-23 81.0 0.1 9.6e-23 81.0 0.1 4.4 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EMR67340.1 - 3.5e-14 52.7 3.1 3.5e-14 52.7 3.1 3.1 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR RNase_H PF00075.24 EMR67341.1 - 5.7e-12 46.0 0.0 8.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 RNase H Trypan_PARP PF05887.11 EMR67342.1 - 0.015 15.3 14.6 0.015 15.3 14.6 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Sulfotransfer_4 PF17784.1 EMR67343.1 - 3.1e-42 144.9 0.1 3.7e-42 144.6 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR67343.1 - 0.0042 17.5 0.1 0.007 16.8 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family SNF2_N PF00176.23 EMR67344.1 - 2.7e-38 131.6 2.0 1.8e-27 96.0 0.5 2.9 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR67344.1 - 2.6e-16 59.9 0.0 5.5e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EMR67344.1 - 9.4e-09 35.0 1.0 9.4e-09 35.0 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR67344.1 - 6e-08 32.4 2.2 1.3e-07 31.4 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EMR67344.1 - 8.9e-07 29.1 1.2 1.8e-06 28.1 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EMR67344.1 - 1.3e-06 28.1 5.1 3.6e-06 26.8 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMR67344.1 - 2.8e-06 27.5 4.6 2.8e-06 27.5 4.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EMR67344.1 - 7.5e-06 25.9 3.7 2.1e-05 24.5 3.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMR67344.1 - 8.1e-06 25.7 4.5 1.9e-05 24.6 4.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EMR67344.1 - 0.00032 20.8 6.6 0.00032 20.8 6.6 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING ERCC3_RAD25_C PF16203.5 EMR67344.1 - 0.0027 17.0 0.0 0.0062 15.8 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_11 PF17123.5 EMR67344.1 - 0.0098 15.6 0.7 0.025 14.3 0.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 EMR67344.1 - 0.012 15.4 4.6 0.031 14.1 4.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 EMR67344.1 - 0.015 15.2 0.8 0.059 13.3 0.2 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) LOH1CR12 PF10158.9 EMR67344.1 - 0.045 13.8 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 Tumour suppressor protein DZR PF12773.7 EMR67344.1 - 0.055 13.5 6.0 0.11 12.5 6.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 EMR67344.1 - 0.37 10.7 8.5 5.6 6.9 8.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 ketoacyl-synt PF00109.26 EMR67345.1 - 3.9e-74 249.4 0.0 6.9e-74 248.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EMR67345.1 - 3.4e-50 170.5 0.0 3.7e-48 163.8 0.0 2.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 EMR67345.1 - 1.9e-36 125.6 0.0 3.4e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EMR67345.1 - 1.2e-31 110.5 0.7 2.7e-31 109.3 0.7 1.5 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR67345.1 - 4.4e-28 97.7 0.1 1.6e-27 95.9 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR67345.1 - 5.4e-17 62.3 0.0 1.4e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EMR67345.1 - 4.4e-14 52.5 0.0 1.7e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PS-DH PF14765.6 EMR67345.1 - 1.5e-13 50.6 0.0 5.3e-11 42.3 0.0 2.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.25 EMR67345.1 - 9.3e-12 44.8 0.0 4.9e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.12 EMR67345.1 - 5.3e-08 33.5 0.0 1.3e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR67345.1 - 1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 EMR67345.1 - 1.7e-05 24.0 0.0 4.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 EMR67345.1 - 6.2e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 EMR67345.1 - 0.00013 22.5 0.0 0.00033 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR67345.1 - 0.0004 20.2 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR67345.1 - 0.00088 19.6 0.1 0.0087 16.4 0.0 2.8 2 1 0 2 2 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EMR67345.1 - 0.0021 17.5 0.0 0.023 14.1 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EMR67345.1 - 0.0058 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.6 EMR67345.1 - 0.072 13.8 0.0 0.22 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Semialdhyde_dh PF01118.24 EMR67345.1 - 0.094 13.2 0.0 0.34 11.4 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ACP_syn_III PF08545.10 EMR67345.1 - 0.22 11.4 0.9 3.4 7.6 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Trp_DMAT PF11991.8 EMR67346.1 - 1.1e-89 301.4 0.0 4.2e-89 299.5 0.0 1.7 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase BPL_LplA_LipB PF03099.19 EMR67347.1 - 0.00049 20.0 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3938 PF13074.6 EMR67348.1 - 0.0022 18.2 0.6 0.0054 16.9 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3938) Clr5 PF14420.6 EMR67349.1 - 2.6e-18 66.0 0.6 7e-18 64.6 0.6 1.8 1 0 0 1 1 1 1 Clr5 domain Ran-binding PF05508.11 EMR67350.1 - 5.4e-48 163.6 0.0 7.8e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein NMO PF03060.15 EMR67351.1 - 0.031 13.7 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase GTP_EFTU PF00009.27 EMR67352.1 - 1.2e-29 103.3 0.2 1.3e-16 60.7 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMR67352.1 - 2.5e-29 101.8 0.3 7e-29 100.4 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMR67352.1 - 7.9e-09 35.8 2.3 4.5e-08 33.4 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TFIIA PF03153.13 EMR67352.1 - 0.17 11.9 14.6 0.27 11.2 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNF2_N PF00176.23 EMR67353.1 - 1.1e-66 225.0 3.6 2.5e-65 220.5 1.1 2.9 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR67353.1 - 6.9e-16 58.6 0.0 1.8e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR67353.1 - 4.7e-07 30.0 0.1 1.7e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMR67353.1 - 4.4e-06 26.6 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 EMR67353.1 - 0.03 14.0 0.6 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 DEAD_2 PI3K_1B_p101 PF10486.9 EMR67353.1 - 5.1 4.8 18.8 2 6.1 10.5 2.1 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAD_binding_3 PF01494.19 EMR67355.1 - 4.6e-17 62.3 1.4 4.1e-10 39.4 0.3 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMR67355.1 - 5.3e-05 23.4 0.1 0.00014 22.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR67355.1 - 0.0018 17.6 0.0 0.029 13.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR67355.1 - 0.022 14.0 0.1 0.91 8.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR67355.1 - 0.063 13.8 0.1 0.7 10.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR67355.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Herpes_gE PF02480.16 EMR67357.1 - 0.098 11.4 0.0 0.33 9.7 0.1 1.7 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E 2-Hacid_dh_C PF02826.19 EMR67358.1 - 1.8e-39 135.0 0.1 1.8e-38 131.7 0.0 2.5 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 EMR67358.1 - 1.1e-20 74.2 0.4 1.1e-20 74.2 0.4 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EMR67358.1 - 1.2e-19 70.9 0.2 3.9e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding 2-Hacid_dh PF00389.30 EMR67358.1 - 2.3e-08 33.8 0.0 7.2e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Semialdhyde_dh PF01118.24 EMR67358.1 - 0.0019 18.6 0.4 0.13 12.7 0.1 2.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMR67358.1 - 0.0042 16.1 0.1 0.0073 15.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMR67358.1 - 0.0047 16.4 0.2 0.019 14.4 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EMR67358.1 - 0.029 14.4 0.3 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AOC_like PF18678.1 EMR67358.1 - 0.085 12.5 0.2 0.3 10.7 0.2 1.9 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain DapB_N PF01113.20 EMR67358.1 - 0.29 11.3 2.6 3.4 7.8 0.2 2.8 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 EMR67360.1 - 1.8e-35 122.2 0.3 2.4e-35 121.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67360.1 - 7.1e-32 110.8 0.2 9.9e-32 110.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67360.1 - 4.7e-10 39.7 0.2 1.1e-09 38.5 0.2 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EMR67360.1 - 0.017 14.1 0.0 2.4 7.1 0.0 2.4 2 1 1 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Flu_PB1 PF00602.17 EMR67360.1 - 0.071 11.2 0.0 0.097 10.8 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Sorting_nexin PF03700.13 EMR67361.1 - 0.065 13.8 0.4 0.18 12.4 0.0 1.9 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain Titin_Z PF09042.11 EMR67361.1 - 0.14 12.1 0.4 0.28 11.2 0.4 1.4 1 0 0 1 1 1 0 Titin Z Kinesin PF00225.23 EMR67362.1 - 9.1e-65 218.8 0.4 9.1e-65 218.8 0.4 3.1 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EMR67362.1 - 2.8e-33 115.0 0.0 1.4e-32 112.7 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 EMR67362.1 - 0.34 11.2 0.0 0.34 11.2 0.0 4.8 5 0 0 5 5 5 0 AAA domain MUG113 PF13455.6 EMR67362.1 - 0.59 10.9 6.7 1.8 9.3 0.8 4.1 3 1 0 3 3 3 0 Meiotically up-regulated gene 113 AAA_16 PF13191.6 EMR67362.1 - 1.3 9.4 0.0 1.3 9.4 0.0 4.4 2 1 1 3 3 3 0 AAA ATPase domain DinB_2 PF12867.7 EMR67363.1 - 0.076 13.5 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 DinB superfamily p450 PF00067.22 EMR67364.1 - 7.7e-11 41.4 0.0 8.9e-11 41.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 EMR67364.1 - 0.25 11.1 0.4 0.49 10.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Glyco_hydro_3_C PF01915.22 EMR67365.1 - 1.3e-40 139.6 0.0 2.4e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR67365.1 - 5.6e-29 101.5 0.0 8.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR67365.1 - 2.7e-07 30.6 0.0 5.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Alpha-L-AF_C PF06964.12 EMR67366.1 - 1.1e-32 113.5 0.0 1.6e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_25 PF01183.20 EMR67367.1 - 8.6e-40 136.8 0.0 9.7e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 BTB PF00651.31 EMR67368.1 - 0.021 15.1 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain AHSP PF09236.10 EMR67368.1 - 0.13 12.8 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein FrhB_FdhB_N PF04422.13 EMR67369.1 - 0.07 13.3 0.2 2.2 8.5 0.0 2.7 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term PRIMA1 PF16101.5 EMR67369.1 - 2.1 8.4 12.1 2 8.5 8.7 2.7 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EMR67369.1 - 3.6 7.0 18.4 0.2 11.1 8.7 2.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal EMG1 PF03587.14 EMR67370.1 - 8.7e-78 260.4 0.0 1e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PgaD PF13994.6 EMR67371.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 PgaD-like protein PrgI PF12666.7 EMR67371.1 - 0.01 16.5 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 0 PrgI family protein UPF0014 PF03649.13 EMR67371.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) CorA PF01544.18 EMR67371.1 - 0.079 12.3 5.8 0.22 10.8 5.8 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3500 PF12006.8 EMR67371.1 - 0.16 11.4 0.9 7.2 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) Ribosomal_S17 PF00366.20 EMR67372.1 - 2e-20 72.6 0.7 3.9e-20 71.7 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 KNOX2 PF03791.13 EMR67373.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 KNOX2 domain eIF2A PF08662.11 EMR67374.1 - 7.8e-34 117.3 1.2 1.3e-30 106.8 0.1 4.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EMR67374.1 - 0.0019 17.9 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EMR67374.1 - 0.0097 16.7 1.0 4.9 8.2 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat MciZ PF13072.6 EMR67374.1 - 0.13 12.1 0.3 0.3 11.0 0.3 1.6 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Pkinase PF00069.25 EMR67375.1 - 2.2e-43 148.6 0.0 7.5e-42 143.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EMR67375.1 - 1.3e-42 145.0 0.0 3.1e-42 143.7 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EMR67375.1 - 5.6e-24 84.8 0.0 2.1e-22 79.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EMR67375.1 - 3.9e-08 32.8 0.1 0.00035 20.4 0.0 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 EMR67375.1 - 0.0053 16.4 0.7 0.03 13.9 0.7 2.3 1 1 0 1 1 1 1 PQQ-like domain Pkinase_fungal PF17667.1 EMR67375.1 - 0.007 15.2 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EMR67375.1 - 0.0094 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EMR67375.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 EMR67375.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.24 EMR67376.1 - 1.5e-139 465.8 11.5 1.8e-139 465.6 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.12 EMR67376.1 - 0.028 14.8 0.1 0.083 13.3 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1132) CRM1_repeat PF18777.1 EMR67376.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF5442 PF17514.2 EMR67376.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) FA_desaturase PF00487.24 EMR67378.1 - 3e-23 82.9 19.9 1.5e-22 80.7 19.9 2.1 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EMR67378.1 - 4.7e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) RHS_repeat PF05593.14 EMR67380.1 - 0.0062 17.0 66.2 0.15 12.6 0.4 15.5 13 3 2 15 15 15 6 RHS Repeat RabGAP-TBC PF00566.18 EMR67381.1 - 3.5e-32 111.8 0.0 6.5e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EMR67381.1 - 2.7e-09 35.9 0.5 2.7e-09 35.9 0.5 1.5 2 0 0 2 2 2 1 SBE2, cell-wall formation zf-C3HC4_3 PF13920.6 EMR67383.1 - 7.6e-05 22.5 10.3 7.6e-05 22.5 10.3 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_10 PF00331.20 EMR67385.1 - 9.2e-90 301.0 0.0 1e-89 300.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.24 EMR67385.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF1653 PF07866.11 EMR67385.1 - 0.17 12.2 0.1 1.7 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1653) SWIB PF02201.18 EMR67386.1 - 9.3e-31 105.5 0.9 3.1e-30 103.9 0.3 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 EMR67386.1 - 4.6e-16 58.5 0.8 9.6e-16 57.5 0.5 1.7 2 0 0 2 2 2 1 DEK C terminal domain SRP-alpha_N PF04086.13 EMR67386.1 - 1.4 8.7 14.9 1.8 8.4 14.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DTHCT PF08070.11 EMR67386.1 - 5 7.9 27.3 0.99 10.2 9.1 2.4 1 1 1 2 2 2 0 DTHCT (NUC029) region Presenilin PF01080.17 EMR67386.1 - 7.7 5.2 5.3 9 4.9 5.3 1.1 1 0 0 1 1 1 0 Presenilin Glyco_hydro_3_C PF01915.22 EMR67387.1 - 2.3e-53 181.2 0.0 3.2e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR67387.1 - 1.4e-43 149.5 0.0 2.1e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR67387.1 - 5.7e-23 80.8 0.2 1.2e-22 79.8 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EMR67387.1 - 1.9e-18 66.7 0.0 3.4e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Phage_tail_X PF05489.12 EMR67387.1 - 0.07 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Phage Tail Protein X KfrA_N PF11740.8 EMR67388.1 - 0.004 17.8 1.3 0.004 17.8 1.3 1.8 2 1 0 2 2 2 1 Plasmid replication region DNA-binding N-term FlxA PF14282.6 EMR67388.1 - 0.0049 16.8 2.8 0.0049 16.8 2.8 1.4 1 1 0 1 1 1 1 FlxA-like protein Spc7 PF08317.11 EMR67388.1 - 0.01 14.7 0.5 0.01 14.7 0.5 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein YscO PF07321.12 EMR67388.1 - 0.019 14.9 7.5 0.019 14.9 7.5 1.9 2 0 0 2 2 2 0 Type III secretion protein YscO Med9 PF07544.13 EMR67388.1 - 0.044 13.9 1.7 4.8 7.3 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Ead_Ea22 PF13935.6 EMR67388.1 - 0.046 14.4 7.1 0.55 10.9 3.8 2.0 1 1 1 2 2 2 0 Ead/Ea22-like protein DUF4259 PF14078.6 EMR67388.1 - 0.051 14.3 2.0 0.063 14.0 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) SKA1 PF07160.12 EMR67388.1 - 0.083 12.7 6.1 0.099 12.5 6.1 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Sec6 PF06046.13 EMR67388.1 - 0.098 11.0 2.5 0.11 10.8 2.5 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 ApoO PF09769.9 EMR67388.1 - 0.27 11.2 3.6 0.21 11.5 0.9 2.2 2 1 0 2 2 2 0 Apolipoprotein O Mis14 PF08641.12 EMR67388.1 - 0.29 11.5 9.2 0.34 11.2 2.5 2.1 2 0 0 2 2 2 0 Kinetochore protein Mis14 like BBP1_C PF15272.6 EMR67388.1 - 1.6 8.5 7.7 1 9.2 0.4 2.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal TPR_MLP1_2 PF07926.12 EMR67388.1 - 5 7.2 13.2 9 6.4 12.9 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF604 PF04646.12 EMR67391.1 - 1.5e-12 47.5 0.0 7.8e-11 41.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.16 EMR67391.1 - 3e-08 33.4 0.0 6.4e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Fringe-like PBP1_TM PF14812.6 EMR67393.1 - 2.1 8.8 7.0 3.3 8.2 6.1 1.9 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldolase_II PF00596.21 EMR67394.1 - 5.3e-49 166.7 0.6 6.8e-49 166.3 0.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_C41 PF05417.11 EMR67394.1 - 0.095 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Hepatitis E cysteine protease Abhydrolase_3 PF07859.13 EMR67395.1 - 1.8e-30 106.4 0.0 2.3e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR67395.1 - 0.00017 20.6 0.1 0.00033 19.7 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 EMR67395.1 - 0.01 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_transf_90 PF05686.12 EMR67396.1 - 8.6e-14 51.2 0.2 9e-10 38.0 0.0 3.5 3 1 0 3 3 3 3 Glycosyl transferase family 90 DHHA2 PF02833.14 EMR67397.1 - 1.9e-16 60.6 0.1 3.2e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EMR67397.1 - 2.1e-06 27.9 0.0 3.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 DHH family UBA_4 PF14555.6 EMR67397.1 - 0.065 13.1 0.4 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain Mpv17_PMP22 PF04117.12 EMR67398.1 - 1.8e-17 63.3 3.9 3.1e-17 62.6 3.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ApbA PF02558.16 EMR67399.1 - 7.2e-25 87.4 0.0 8e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA CoA_binding PF02629.19 EMR67399.1 - 0.093 13.4 0.4 0.31 11.7 0.4 1.8 1 1 0 1 1 1 0 CoA binding domain ThiF PF00899.21 EMR67399.1 - 0.1 11.9 1.8 0.54 9.6 1.5 1.9 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.19 EMR67399.1 - 0.1 11.8 0.4 0.13 11.5 0.4 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EMR67399.1 - 0.1 11.8 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SM-ATX PF14438.6 EMR67399.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Ataxin 2 SM domain PglD_N PF17836.1 EMR67399.1 - 0.13 12.9 0.3 0.29 11.8 0.3 1.7 1 1 0 1 1 1 0 PglD N-terminal domain FAD_binding_2 PF00890.24 EMR67399.1 - 0.21 10.7 1.5 0.36 9.9 1.5 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EMR67399.1 - 0.22 10.6 0.8 0.41 9.7 0.6 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 EMR67399.1 - 0.27 10.8 1.7 0.44 10.1 1.5 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase WD40 PF00400.32 EMR67401.1 - 1.6e-17 63.5 0.6 5.5e-07 30.2 0.4 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR67401.1 - 2.2e-08 34.3 0.1 0.0062 16.8 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR67401.1 - 1.2e-05 24.1 0.4 0.062 11.9 0.1 2.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EMR67401.1 - 0.00045 20.1 0.1 0.0018 18.2 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EMR67401.1 - 0.012 14.2 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 EMR67401.1 - 0.012 14.7 0.0 0.042 12.9 0.0 1.6 1 1 1 2 2 2 0 Coatomer WD associated region Phage_term_sma PF07141.11 EMR67401.1 - 0.089 12.6 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Putative bacteriophage terminase small subunit Ge1_WD40 PF16529.5 EMR67401.1 - 0.09 11.7 0.0 3.8 6.4 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_5 PF13857.6 EMR67402.1 - 7.7e-11 42.0 0.2 8.9e-08 32.3 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR67402.1 - 5.6e-06 26.9 0.2 7e-05 23.3 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR67402.1 - 2.7e-05 24.6 0.1 9.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR67402.1 - 0.00023 21.3 1.6 0.0018 18.6 0.2 3.0 3 0 0 3 3 3 1 Ankyrin repeat HWE_HK PF07536.14 EMR67402.1 - 0.007 17.1 0.0 0.05 14.3 0.0 2.1 2 0 0 2 2 2 1 HWE histidine kinase Ank PF00023.30 EMR67402.1 - 0.031 14.7 0.3 0.65 10.5 0.1 2.9 3 1 0 3 3 3 0 Ankyrin repeat Mito_carr PF00153.27 EMR67403.1 - 1.9e-42 143.1 4.4 1.2e-18 66.8 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Glycos_transf_3 PF00591.21 EMR67404.1 - 5.8e-62 209.6 0.0 1.1e-61 208.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EMR67404.1 - 3.9e-10 39.4 0.0 9.6e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Vac_ImportDeg PF09783.9 EMR67406.1 - 7.3e-63 211.2 0.6 1.1e-62 210.6 0.6 1.3 1 0 0 1 1 1 1 Vacuolar import and degradation protein PM0188 PF11477.8 EMR67406.1 - 0.0082 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Sialyltransferase PMO188 DUF3439 PF11921.8 EMR67406.1 - 0.037 14.0 0.1 0.037 14.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LuxQ-periplasm PF09308.10 EMR67406.1 - 0.12 11.9 1.0 0.21 11.1 1.0 1.3 1 0 0 1 1 1 0 LuxQ, periplasmic RNA_lig_T4_1 PF09511.10 EMR67407.1 - 7.3e-87 290.8 0.0 1.5e-86 289.9 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 EMR67407.1 - 1.6e-86 289.9 0.0 2.6e-86 289.2 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 EMR67407.1 - 1.1e-54 185.0 0.7 2.1e-54 184.1 0.7 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain 2_5_RNA_ligase2 PF13563.6 EMR67407.1 - 0.074 13.0 0.0 7.9 6.4 0.0 2.5 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily RNA_ligase PF09414.10 EMR67407.1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA ligase SGL PF08450.12 EMR67408.1 - 1.5e-05 24.7 0.0 0.00096 18.8 0.0 2.3 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region ABC2_membrane PF01061.24 EMR67409.1 - 1.4e-26 93.2 32.5 2.3e-21 76.2 17.1 2.9 2 1 1 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EMR67409.1 - 1.2e-11 44.3 0.0 1.2e-11 44.3 0.0 3.4 4 0 0 4 4 4 1 CDR ABC transporter ABC_tran PF00005.27 EMR67409.1 - 3.8e-07 30.7 0.1 6.7e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 EMR67409.1 - 9.7e-07 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMR67409.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EMR67409.1 - 0.0043 16.8 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMR67409.1 - 0.035 14.6 0.2 0.035 14.6 0.2 1.5 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 EMR67409.1 - 0.042 14.2 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EMR67409.1 - 0.057 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 EMR67409.1 - 0.068 12.3 22.2 0.4 9.7 8.6 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_28 PF13521.6 EMR67409.1 - 0.086 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EMR67409.1 - 0.11 12.3 0.5 0.17 11.7 0.1 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EMR67409.1 - 0.12 12.0 0.5 0.18 11.3 0.5 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain OCD_Mu_crystall PF02423.15 EMR67409.1 - 0.13 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family AAA_18 PF13238.6 EMR67409.1 - 0.14 12.7 0.1 0.26 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMR67409.1 - 0.17 12.2 0.1 0.31 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L10 PF00466.20 EMR67410.1 - 0.0004 20.5 0.0 0.0041 17.2 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L10 IMUP PF15761.5 EMR67410.1 - 1.4 9.6 10.7 4.2 8.1 10.7 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein TPR_14 PF13428.6 EMR67411.1 - 0.00018 22.1 5.9 0.54 11.2 0.7 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat PRD PF00874.20 EMR67411.1 - 0.13 12.6 0.1 7.3 7.0 0.0 2.9 2 0 0 2 2 2 0 PRD domain TPR_19 PF14559.6 EMR67411.1 - 3.2 8.3 7.4 14 6.3 1.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EMR67411.1 - 5.4 7.2 8.9 1.7 8.9 3.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMR67411.1 - 5.7 7.7 10.1 59 4.4 3.8 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0020 PF01170.18 EMR67413.1 - 3e-08 33.6 0.0 2.8e-06 27.2 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 ChAPs PF09295.10 EMR67415.1 - 6.1e-154 512.8 0.0 8e-154 512.4 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 EMR67415.1 - 1e-06 28.3 0.4 0.12 12.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMR67415.1 - 2.2e-05 24.3 0.1 0.034 14.4 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMR67415.1 - 4.4e-05 24.0 2.8 0.25 12.3 0.2 5.2 3 1 2 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR67415.1 - 7.1e-05 22.6 1.0 0.11 12.7 1.7 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EMR67415.1 - 0.0002 21.5 0.1 0.018 15.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR67415.1 - 0.001 19.5 0.1 6.4 7.4 0.0 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR67415.1 - 0.0017 18.1 0.5 2.6 8.0 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TAF4 PF05236.14 EMR67415.1 - 0.0043 16.9 5.1 0.0071 16.1 5.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TPR_12 PF13424.6 EMR67415.1 - 0.019 15.2 1.0 12 6.3 0.8 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR67415.1 - 0.033 14.4 4.7 8.1 6.7 0.1 4.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EMR67415.1 - 0.033 14.8 0.1 47 4.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AdoHcyase PF05221.17 EMR67417.1 - 1.1e-128 428.6 0.0 1.3e-74 251.1 0.3 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EMR67417.1 - 3.8e-83 277.4 3.2 5.9e-83 276.8 3.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMR67417.1 - 2.5e-05 23.7 0.2 5.3e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EMR67417.1 - 0.018 14.7 0.4 0.033 13.8 0.4 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Mago_nashi PF02792.14 EMR67418.1 - 8.7e-44 149.1 0.1 9.4e-44 149.0 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein JAB PF01398.21 EMR67419.1 - 1.1e-05 25.4 0.2 0.00046 20.2 0.2 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF5513 PF17632.2 EMR67419.1 - 0.083 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5513) Sec39 PF08314.11 EMR67420.1 - 1.7e-181 605.4 7.9 2.1e-69 234.8 0.0 3.0 1 1 2 3 3 3 3 Secretory pathway protein Sec39 MFS_1 PF07690.16 EMR67421.1 - 2.3e-28 99.2 23.6 2.3e-28 99.2 23.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1218 PF06749.12 EMR67421.1 - 0.14 12.7 1.3 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Med5 PF08689.10 EMR67422.1 - 5.2e-15 54.4 0.0 1.5e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 Mediator complex subunit Med5 SRP_TPR_like PF17004.5 EMR67423.1 - 1.4e-22 79.9 0.0 3.8e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 EMR67423.1 - 8.9e-16 58.1 3.2 2.6e-15 56.6 3.2 1.8 1 0 0 1 1 1 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 EMR67423.1 - 1.4e-05 25.2 2.7 0.0015 18.7 0.7 3.2 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EMR67423.1 - 2.5e-05 24.7 12.2 0.11 13.0 0.5 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMR67423.1 - 0.0041 17.8 17.9 26 6.0 0.3 7.9 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMR67423.1 - 0.027 14.6 14.1 1.7 9.0 0.4 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMR67423.1 - 0.028 15.1 0.6 0.028 15.1 0.6 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat GGA_N-GAT PF18308.1 EMR67423.1 - 0.13 11.9 0.7 12 5.6 0.0 2.9 3 0 0 3 3 3 0 GGA N-GAT domain SPO22 PF08631.10 EMR67423.1 - 0.21 11.0 1.6 1.4 8.3 0.1 2.6 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_1 PF00515.28 EMR67423.1 - 2.2 8.2 7.6 5.7 6.9 0.3 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EMR67423.1 - 3 8.0 4.7 11 6.2 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 EMR67424.1 - 4.6e-08 32.9 0.1 7.7e-08 32.1 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_60s PF00428.19 EMR67424.1 - 3.5 8.3 5.4 0.36 11.4 0.3 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein SNARE PF05739.19 EMR67425.1 - 3.7e-13 49.2 1.6 6.8e-13 48.4 0.5 2.1 2 0 0 2 2 2 1 SNARE domain DUF4611 PF15387.6 EMR67425.1 - 0.0068 16.6 0.7 0.027 14.7 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Syntaxin PF00804.25 EMR67425.1 - 0.6 9.7 17.5 0.076 12.7 4.0 2.3 2 0 0 2 2 2 0 Syntaxin Peptidase_S64 PF08192.11 EMR67425.1 - 9.9 4.5 11.2 13 4.1 11.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4965 PF16335.5 EMR67426.1 - 2.1e-65 219.6 0.1 5.6e-51 172.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EMR67426.1 - 7.7e-47 159.8 0.3 6.9e-46 156.7 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 EMR67426.1 - 6.6e-43 147.1 1.7 1.1e-42 146.3 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) Glyco_hydr_116N PF12215.8 EMR67426.1 - 2.9e-05 23.7 0.8 4.7e-05 23.0 0.8 1.2 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term RNase_J_C PF17770.1 EMR67426.1 - 0.082 14.0 0.1 0.25 12.4 0.1 1.8 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain NAD_binding_1 PF00175.21 EMR67427.1 - 8.8e-06 26.3 0.0 0.0065 17.1 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMR67427.1 - 0.0088 16.2 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EMR67427.1 - 0.017 15.4 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EF-hand_1 PF00036.32 EMR67428.1 - 6.1e-38 125.5 13.9 8.5e-10 37.5 0.9 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EMR67428.1 - 3.2e-33 114.0 5.4 4.1e-16 59.2 1.8 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EMR67428.1 - 2e-30 104.4 13.4 2.9e-15 55.8 1.0 4.0 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 EMR67428.1 - 4.2e-27 91.7 8.2 2.1e-09 36.6 0.2 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EMR67428.1 - 2.3e-24 83.7 8.9 2.8e-06 26.6 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EMR67428.1 - 3.2e-15 56.2 0.4 2.6e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EMR67428.1 - 1.7e-08 34.3 2.0 0.0041 17.0 0.2 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EMR67428.1 - 3e-08 34.0 0.9 0.006 16.9 0.5 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EMR67428.1 - 1.3e-06 28.3 0.0 0.0087 16.1 0.0 3.0 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) TerB PF05099.13 EMR67428.1 - 0.00012 22.0 0.1 0.36 10.8 0.0 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 EMR67428.1 - 0.0002 21.7 0.3 0.16 12.3 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb4 Caleosin PF05042.13 EMR67428.1 - 0.00049 20.1 2.0 0.48 10.3 0.0 3.3 1 1 3 4 4 4 2 Caleosin related protein EF-hand_11 PF08976.11 EMR67428.1 - 0.0011 19.8 0.1 0.057 14.3 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain DUF3349 PF11829.8 EMR67428.1 - 0.0031 18.3 0.4 2.9 8.7 0.0 2.8 1 1 3 4 4 4 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 EMR67428.1 - 0.0059 16.8 6.1 0.43 10.8 0.8 2.7 2 2 0 2 2 2 2 Dockerin type I domain SurA_N_2 PF13623.6 EMR67428.1 - 0.0099 15.7 0.8 0.45 10.4 0.1 2.4 1 1 1 2 2 2 1 SurA N-terminal domain EFhand_Ca_insen PF08726.10 EMR67428.1 - 0.01 15.9 2.1 0.13 12.4 0.3 3.0 2 2 0 2 2 2 0 Ca2+ insensitive EF hand Poly_export PF02563.16 EMR67428.1 - 0.039 14.2 0.0 0.31 11.3 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein EF-hand_14 PF17959.1 EMR67428.1 - 0.058 13.7 0.8 4.6 7.7 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain RuvA_C PF07499.13 EMR67428.1 - 0.082 13.4 0.1 9.3 6.8 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 EMR67428.1 - 0.085 13.0 0.2 1.5 9.0 0.0 2.3 2 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF5132 PF17195.4 EMR67428.1 - 0.16 12.1 0.5 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Spore_III_AB PF09548.10 EMR67428.1 - 0.22 11.6 0.6 0.55 10.3 0.5 1.8 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Jnk-SapK_ap_N PF09744.9 EMR67429.1 - 2.2 8.5 10.3 6.4 7.0 7.5 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 WD40 PF00400.32 EMR67430.1 - 1.3e-12 48.0 1.7 0.043 14.7 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR67430.1 - 0.0022 18.2 0.0 46 4.4 0.0 4.8 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain COX7a PF02238.15 EMR67431.1 - 1.7e-16 60.4 1.9 1.9e-16 60.2 1.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Glyco_hydro_47 PF01532.20 EMR67432.1 - 3.2e-166 553.8 0.0 3.7e-166 553.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPR_2 PF07719.17 EMR67435.1 - 4.1e-08 32.7 7.7 0.00012 21.9 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMR67435.1 - 1.1e-05 25.9 1.8 0.00013 22.4 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR67435.1 - 3e-05 23.6 0.6 0.055 13.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMR67435.1 - 0.0005 20.1 1.7 0.0045 17.1 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR67435.1 - 0.006 17.2 8.5 0.0091 16.6 4.1 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMR67435.1 - 0.0071 16.6 7.0 0.042 14.2 2.4 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMR67435.1 - 0.034 14.8 1.9 0.73 10.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR67435.1 - 0.14 13.0 0.6 0.14 13.0 0.6 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Binary_toxB_2 PF17475.2 EMR67435.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 2 TPR_4 PF07721.14 EMR67435.1 - 0.64 10.8 11.2 0.65 10.8 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMR67435.1 - 2.1 8.3 7.6 17 5.4 1.9 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SSF PF00474.17 EMR67436.1 - 0.0088 14.9 0.6 0.011 14.7 0.6 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.22 EMR67437.1 - 2.2e-19 69.0 0.0 3.4e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMR67437.1 - 0.00027 20.5 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_8 PF01501.20 EMR67439.1 - 7.2e-10 38.9 1.1 1.5e-07 31.2 0.8 3.0 1 1 1 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EMR67439.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative TFIIA PF03153.13 EMR67440.1 - 0.00017 21.8 0.6 0.00025 21.2 0.6 1.3 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RapA_C PF12137.8 EMR67440.1 - 0.03 13.3 0.7 0.046 12.7 0.7 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal UPF0149 PF03695.13 EMR67440.1 - 0.13 12.6 3.2 0.22 11.8 3.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0149) DUF2018 PF09442.10 EMR67440.1 - 0.14 13.2 0.1 0.57 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) NOA36 PF06524.12 EMR67440.1 - 4.7 6.4 14.5 7.6 5.8 14.5 1.3 1 0 0 1 1 1 0 NOA36 protein Hydrolase_4 PF12146.8 EMR67441.1 - 1.8e-47 161.6 0.0 2.2e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR67441.1 - 6.6e-15 56.3 3.8 8.5e-15 56.0 3.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR67441.1 - 7.2e-12 45.5 1.7 4.8e-11 42.8 0.4 2.6 2 2 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR67441.1 - 0.00012 21.6 0.5 0.0042 16.6 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family Adaptin_N PF01602.20 EMR67442.1 - 4.7e-129 431.3 0.6 6e-129 431.0 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EMR67442.1 - 2.3e-21 76.2 0.0 5.5e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EMR67442.1 - 3.1e-09 37.1 1.8 0.00013 22.0 0.0 3.7 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMR67442.1 - 1e-06 29.0 0.7 0.035 14.5 0.0 4.2 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EMR67442.1 - 0.00042 20.3 0.9 12 6.5 0.1 5.2 5 1 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 EMR67442.1 - 0.02 15.4 0.1 51 4.5 0.0 5.1 4 1 0 4 4 4 0 HEAT-like repeat RICTOR_M PF14666.6 EMR67442.1 - 0.046 13.5 0.5 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain TIP120 PF08623.10 EMR67442.1 - 0.07 12.9 1.0 4.4 7.1 0.1 3.2 3 1 0 3 3 3 0 TATA-binding protein interacting (TIP20) Arm PF00514.23 EMR67442.1 - 0.093 12.8 0.1 1.4e+02 2.7 0.0 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 EMR67442.1 - 0.12 11.1 0.0 0.33 9.7 0.0 1.7 1 1 1 2 2 2 0 Apoptosis inhibitory protein 5 (API5) zf-C2H2 PF00096.26 EMR67444.1 - 3.2e-06 27.3 18.2 0.16 12.5 1.4 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR67444.1 - 0.017 15.9 19.5 0.29 12.1 0.7 4.9 4 1 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 EMR67444.1 - 0.29 11.6 3.2 3.6 8.1 0.6 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMR67444.1 - 0.65 10.4 6.4 2.7 8.4 0.6 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Nitroreductase PF00881.24 EMR67446.1 - 3.6e-19 69.5 0.6 4.3e-18 65.9 0.6 2.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EMR67446.1 - 0.0014 18.2 0.0 0.039 13.5 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase TRAP_alpha PF03896.16 EMR67447.1 - 1.3e-13 50.9 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF4352 PF11611.8 EMR67447.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) ABC_membrane PF00664.23 EMR67448.1 - 7e-54 183.3 10.2 9.1e-54 182.9 10.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMR67448.1 - 5.1e-35 121.0 0.0 1.7e-34 119.2 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMR67448.1 - 1.2e-05 24.9 0.0 0.00045 19.7 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMR67448.1 - 0.00084 19.6 0.1 0.0069 16.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMR67448.1 - 0.0081 15.9 0.2 0.021 14.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EMR67448.1 - 0.018 15.5 0.5 0.85 10.0 0.3 3.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR67448.1 - 0.022 15.2 0.1 0.077 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EMR67448.1 - 0.043 13.8 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EMR67448.1 - 0.071 12.8 0.4 1.6 8.5 0.0 2.6 2 1 1 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 EMR67448.1 - 0.076 13.3 0.9 1.2 9.5 0.9 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CTD_bind PF04818.13 EMR67449.1 - 2.5e-19 69.8 0.3 7.8e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 EMR67449.1 - 0.04 13.9 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Clathrin_lg_ch PF01086.17 EMR67450.1 - 2.7e-73 246.8 6.3 3.1e-73 246.6 6.3 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF5630 PF18632.1 EMR67450.1 - 0.16 11.2 2.6 0.24 10.7 2.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5630) rve_3 PF13683.6 EMR67450.1 - 0.22 11.3 0.7 0.56 10.0 0.7 1.6 1 0 0 1 1 1 0 Integrase core domain Pept_tRNA_hydro PF01195.19 EMR67451.1 - 1.1e-26 93.8 0.0 1.4e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase GGACT PF06094.12 EMR67454.1 - 0.005 17.4 0.1 0.02 15.5 0.1 2.0 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like WD40 PF00400.32 EMR67456.1 - 8.3e-16 58.1 14.4 0.00029 21.6 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR67456.1 - 7.6e-07 29.3 0.0 0.12 12.7 0.0 4.2 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EMR67458.1 - 0.0033 17.2 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMR67458.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 1 1 2 2 2 0 Occluded RNA-recognition motif HILPDA PF15220.6 EMR67458.1 - 0.13 12.4 0.8 0.22 11.7 0.8 1.3 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated Herpes_pp85 PF04637.12 EMR67458.1 - 4.6 5.5 5.3 1.2 7.5 2.9 1.3 1 1 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF846 PF05832.12 EMR67459.1 - 2.3e-52 176.7 7.3 2.8e-52 176.5 7.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DuoxA PF10204.9 EMR67459.1 - 0.024 13.6 5.9 0.4 9.7 0.7 2.1 2 0 0 2 2 2 0 Dual oxidase maturation factor DUF5504 PF17608.2 EMR67459.1 - 0.028 14.5 1.7 0.028 14.5 1.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5504) DUF3445 PF11927.8 EMR67460.1 - 2.2e-78 263.0 0.0 2.9e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Gram_pos_anchor PF00746.21 EMR67460.1 - 0.016 15.1 0.1 0.17 11.9 0.0 2.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Cupin_2 PF07883.11 EMR67461.1 - 2.2e-09 36.9 0.3 3.9e-09 36.1 0.3 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EMR67461.1 - 0.00057 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EMR67461.1 - 0.0026 17.4 0.1 0.0041 16.7 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EMR67461.1 - 0.0033 17.3 0.1 0.0048 16.8 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EMR67461.1 - 0.0042 17.0 0.1 0.0053 16.7 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase EutQ PF06249.12 EMR67461.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ UPF0669 PF17065.5 EMR67461.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 Phage_holin_3_3 PF16083.5 EMR67462.1 - 0.0024 18.0 2.4 0.0024 18.0 2.4 1.6 2 0 0 2 2 2 1 LydA holin phage, holin superfamily III DUF4191 PF13829.6 EMR67462.1 - 4.3 6.6 5.5 3.5 6.9 4.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Glyco_hydro_31 PF01055.26 EMR67463.1 - 1.1e-94 318.2 0.1 1.4e-94 317.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EMR67463.1 - 1.3e-11 44.6 0.0 7.9e-11 42.1 0.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like p450 PF00067.22 EMR67464.1 - 1.7e-05 23.8 0.0 0.016 14.0 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 Zn_clus PF00172.18 EMR67465.1 - 4.2e-09 36.4 7.9 8.3e-09 35.4 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR67465.1 - 0.0079 15.2 0.5 0.019 14.0 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mito_fiss_reg PF05308.11 EMR67465.1 - 0.11 12.5 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator adh_short PF00106.25 EMR67466.1 - 1.7e-22 79.9 0.0 2.7e-22 79.2 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67466.1 - 1.3e-13 51.0 0.0 1.8e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67466.1 - 2.9e-09 37.1 0.1 4e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR67466.1 - 0.0001 21.8 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR67466.1 - 0.0049 16.3 0.0 0.0074 15.7 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Prp19 PF08606.11 EMR67466.1 - 0.036 14.0 0.1 0.077 13.0 0.1 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like THF_DHG_CYH_C PF02882.19 EMR67466.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EMR67466.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TIR-like PF10137.9 EMR67466.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain MFS_1 PF07690.16 EMR67467.1 - 6.3e-31 107.6 31.0 6.3e-31 107.6 31.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_4 PF01565.23 EMR67470.1 - 2.6e-20 72.6 1.6 4e-20 72.0 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.28 EMR67471.1 - 3e-05 24.1 0.0 0.067 13.3 0.0 2.7 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain HET PF06985.11 EMR67472.1 - 5.4e-12 46.3 0.4 1.2e-11 45.2 0.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF747 PF05346.11 EMR67473.1 - 2.6e-37 129.0 0.0 2.8e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF4834 PF16118.5 EMR67473.1 - 0.03 15.3 0.0 0.089 13.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_M16 PF00675.20 EMR67475.1 - 1.8e-14 53.9 0.0 3.3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMR67475.1 - 6.4e-10 39.3 0.0 1.2e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain LEA_3 PF03242.13 EMR67475.1 - 2.2 9.1 7.6 0.2 12.4 1.0 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein CDH-cyt PF16010.5 EMR67476.1 - 6.1e-49 166.2 0.2 7.2e-49 165.9 0.2 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Dioxygenase_C PF00775.21 EMR67477.1 - 9.6e-06 25.1 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Mak10 PF04112.13 EMR67478.1 - 2.1e-60 203.0 0.1 3.3e-60 202.4 0.1 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase GRA6 PF05084.13 EMR67478.1 - 0.55 10.2 4.0 0.82 9.6 4.0 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Cnd2 PF05786.14 EMR67478.1 - 4.8 5.7 5.9 6.9 5.2 5.9 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 SKG6 PF08693.10 EMR67479.1 - 0.019 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SUIM_assoc PF16619.5 EMR67479.1 - 0.027 14.5 0.0 0.066 13.3 0.0 1.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Mito_carr PF00153.27 EMR67480.1 - 1.1e-44 150.3 4.0 1.6e-15 56.7 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein ATP-synt_Eps PF04627.13 EMR67481.1 - 2.2e-17 62.8 1.5 1e-15 57.4 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial ATP synthase epsilon chain CorA PF01544.18 EMR67482.1 - 3.2e-06 26.7 0.2 3.2e-06 26.7 0.2 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Beta-lactamase PF00144.24 EMR67483.1 - 3.3e-33 115.3 0.0 2.4e-32 112.5 0.0 2.2 1 1 1 2 2 2 1 Beta-lactamase Lactamase_B PF00753.27 EMR67484.1 - 3.7e-08 33.6 2.2 3.6e-07 30.4 0.1 2.7 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMR67484.1 - 0.019 14.5 0.1 0.062 12.8 0.0 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain WSC PF01822.19 EMR67485.1 - 2.9e-05 24.2 1.0 2.9e-05 24.2 1.0 4.0 4 0 0 4 4 4 2 WSC domain Peptidase_M28 PF04389.17 EMR67486.1 - 3.5e-27 95.4 0.0 4.9e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMR67486.1 - 5.4e-14 52.0 0.5 9.7e-14 51.2 0.5 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EMR67486.1 - 0.00087 19.0 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Mis14 PF08641.12 EMR67487.1 - 4.2e-15 56.2 0.0 1e-13 51.8 0.0 2.7 2 2 0 2 2 2 1 Kinetochore protein Mis14 like GreA_GreB_N PF03449.15 EMR67487.1 - 0.051 13.7 3.4 1.1 9.5 0.0 3.2 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal IGF2_C PF08365.11 EMR67487.1 - 0.85 9.7 2.8 25 4.9 0.2 2.7 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide Sec7 PF01369.20 EMR67488.1 - 1.1e-28 100.2 0.2 1.9e-28 99.4 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EMR67488.1 - 1.1e-18 67.7 0.0 3.1e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain SPT2 PF08243.11 EMR67488.1 - 0.12 12.9 3.0 0.14 12.7 1.4 1.9 2 0 0 2 2 2 0 SPT2 chromatin protein Prefoldin PF02996.17 EMR67491.1 - 2.9e-34 117.5 0.7 6.3e-34 116.5 0.2 1.7 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 EMR67491.1 - 0.00034 20.5 1.1 0.0087 16.0 0.1 2.8 1 1 1 3 3 3 1 Prefoldin subunit THOC7 PF05615.13 EMR67491.1 - 0.015 15.5 1.2 0.28 11.5 0.2 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Filament PF00038.21 EMR67491.1 - 0.02 14.5 5.9 0.14 11.7 5.9 1.9 1 1 0 1 1 1 0 Intermediate filament protein DUF4201 PF13870.6 EMR67491.1 - 0.036 13.8 0.8 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 EMR67491.1 - 0.094 12.8 0.1 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 EMR67491.1 - 0.13 12.7 1.2 19 5.7 0.1 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 EMR67491.1 - 0.15 12.1 0.6 1 9.4 0.0 2.0 2 0 0 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.11 EMR67491.1 - 0.24 11.9 2.3 11 6.7 2.3 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal End3 PF12761.7 EMR67491.1 - 0.25 11.5 2.2 1.6 8.9 0.1 2.3 2 2 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Folliculin PF11704.8 EMR67492.1 - 5.8e-17 62.2 0.0 6.9e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport K_channel_TID PF07941.11 EMR67492.1 - 0.52 10.8 9.0 2.1 8.9 9.0 1.9 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Mid2 PF04478.12 EMR67493.1 - 0.0044 16.9 0.0 0.0044 16.9 0.0 2.1 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EMR67493.1 - 0.012 15.0 6.3 0.03 13.7 6.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ADH_N PF08240.12 EMR67494.1 - 5.3e-23 81.0 5.6 8.5e-23 80.3 5.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR67494.1 - 5.8e-19 68.4 0.0 9.9e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR67494.1 - 2.7e-10 41.4 0.0 5.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMR67494.1 - 0.076 12.4 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zinc-ribbons_6 PF07191.12 EMR67494.1 - 0.076 13.0 1.1 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbons AlaDh_PNT_C PF01262.21 EMR67494.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AAA PF00004.29 EMR67496.1 - 3.8e-45 153.5 0.1 1.4e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EMR67496.1 - 1e-10 41.4 0.1 7.6e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EMR67496.1 - 7.8e-09 35.6 0.3 2.7e-08 33.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMR67496.1 - 6.3e-08 32.9 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EMR67496.1 - 1.9e-07 31.6 0.5 3.7e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EMR67496.1 - 4.2e-06 26.1 0.0 7.9e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EMR67496.1 - 4.1e-05 23.9 1.3 0.0081 16.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EMR67496.1 - 0.00039 20.2 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EMR67496.1 - 0.00085 19.9 0.0 0.0026 18.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EMR67496.1 - 0.00085 18.9 0.0 0.0078 15.7 0.1 2.3 2 1 0 2 2 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EMR67496.1 - 0.00093 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EMR67496.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 EMR67496.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 EMR67496.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 EMR67496.1 - 0.0016 18.4 0.0 0.024 14.7 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EMR67496.1 - 0.0019 18.2 0.2 0.0087 16.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 EMR67496.1 - 0.0025 17.7 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 EMR67496.1 - 0.0051 16.5 0.1 0.014 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EMR67496.1 - 0.0063 16.5 0.4 0.11 12.4 0.0 2.7 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 EMR67496.1 - 0.0064 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EMR67496.1 - 0.0083 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EMR67496.1 - 0.0093 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EMR67496.1 - 0.011 15.2 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 EMR67496.1 - 0.017 14.9 0.1 0.043 13.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 EMR67496.1 - 0.02 14.6 0.2 0.051 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMR67496.1 - 0.042 13.8 1.2 0.23 11.4 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EMR67496.1 - 0.047 13.5 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EMR67496.1 - 0.053 12.9 1.3 0.56 9.5 0.0 2.4 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.18 EMR67496.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 EMR67496.1 - 0.077 11.9 0.1 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.26 EMR67496.1 - 0.084 12.6 0.2 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.14 EMR67496.1 - 0.098 11.2 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_25 PF13481.6 EMR67496.1 - 0.14 11.8 1.8 0.23 11.0 0.2 2.1 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 EMR67496.1 - 0.14 12.5 0.1 0.41 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMR67496.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 EMR67496.1 - 0.2 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NTP_transf_9 PF04248.12 EMR67497.1 - 1.6e-35 120.8 0.1 2.6e-26 91.3 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) FAD_binding_3 PF01494.19 EMR67498.1 - 5.7e-24 85.0 0.0 9.5e-13 48.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EMR67498.1 - 4.6e-07 29.4 0.1 1.8e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR67498.1 - 7.8e-06 26.0 0.1 3.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR67498.1 - 8.2e-05 22.0 0.1 0.0033 16.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR67498.1 - 0.00013 20.8 0.1 0.0056 15.4 0.0 2.7 3 1 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 EMR67498.1 - 0.0024 18.4 0.2 0.12 12.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR67498.1 - 0.0042 17.1 0.9 0.35 10.8 0.1 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 EMR67498.1 - 0.0076 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EMR67498.1 - 0.0081 15.3 0.7 0.044 12.9 0.0 2.2 2 1 1 3 3 3 1 FAD binding domain TrkA_N PF02254.18 EMR67498.1 - 0.017 15.4 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 EMR67498.1 - 0.019 14.1 0.7 0.1 11.7 0.0 2.3 2 1 1 3 3 3 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EMR67498.1 - 0.023 14.0 0.0 0.079 12.2 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 EMR67498.1 - 0.023 13.8 0.0 0.076 12.1 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EMR67498.1 - 0.048 13.2 0.3 0.1 12.1 0.3 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 EMR67498.1 - 0.053 13.2 0.2 0.27 10.9 0.4 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ala_racemase_N PF01168.20 EMR67499.1 - 3.3e-31 108.6 0.2 4e-31 108.4 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 EMR67499.1 - 7.4e-18 65.0 0.0 1.5e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Glyco_trans_4_4 PF13579.6 EMR67499.1 - 0.009 16.5 0.2 0.067 13.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain MeaB PF03308.16 EMR67499.1 - 0.021 13.8 0.7 0.81 8.6 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Glyco_transf_4 PF13439.6 EMR67499.1 - 0.04 13.9 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 TFIIE_beta PF02186.15 EMR67499.1 - 0.17 12.2 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 TFIIE beta subunit core domain CRAL_TRIO PF00650.20 EMR67500.1 - 8.1e-31 106.9 0.0 1.4e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMR67500.1 - 1.4e-06 28.4 0.1 3.1e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EMR67500.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain AA_permease PF00324.21 EMR67501.1 - 7.6e-105 351.3 36.4 7e-83 278.8 18.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EMR67501.1 - 3.5e-21 75.5 31.6 1.2e-18 67.2 17.3 2.1 1 1 1 2 2 2 2 Amino acid permease NCE101 PF11654.8 EMR67501.1 - 0.13 12.0 1.1 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Non-classical export protein 1 Y_phosphatase PF00102.27 EMR67502.1 - 1e-43 149.6 0.0 9.9e-43 146.4 0.0 2.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EMR67502.1 - 5.1e-07 29.9 0.0 1.9e-05 24.8 0.0 2.8 3 0 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EMR67502.1 - 1.9e-05 24.8 0.0 3.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EMR67502.1 - 0.00035 20.4 0.0 0.00098 18.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HSP20 PF00011.21 EMR67503.1 - 2.3e-11 43.8 0.0 3.8e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EMR67503.1 - 0.0076 15.8 0.1 0.073 12.6 0.0 2.6 2 1 0 2 2 2 1 HSP20-like domain found in ArsA PhoD PF09423.10 EMR67504.1 - 2.1e-05 23.7 0.5 0.00029 20.0 0.5 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase DSPc PF00782.20 EMR67505.1 - 8.8e-17 61.2 0.0 1.9e-16 60.1 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 EMR67505.1 - 1.4e-11 45.0 0.0 3.2e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 EMR67505.1 - 3.8e-06 26.6 0.0 6.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EMR67505.1 - 0.1 12.7 0.1 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate p450 PF00067.22 EMR67506.1 - 4.1e-56 190.7 0.0 6.2e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 OmdA PF13376.6 EMR67507.1 - 5.4e-13 48.7 0.1 5.4e-13 48.7 0.1 2.4 3 0 0 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated KRE1 PF17056.5 EMR67507.1 - 0.042 13.6 0.7 0.92 9.3 0.1 2.5 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 Sialidase PF02973.16 EMR67508.1 - 0.039 13.5 0.1 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Sialidase, N-terminal domain Mito_carr PF00153.27 EMR67510.1 - 4.3e-38 129.1 5.6 1.6e-16 60.0 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein fn3_4 PF16794.5 EMR67511.1 - 0.11 12.4 0.1 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Fibronectin-III type domain CdvA PF18822.1 EMR67511.1 - 0.12 12.2 0.1 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Pkinase PF00069.25 EMR67512.1 - 4.6e-67 226.2 0.0 6.2e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR67512.1 - 7e-41 140.2 0.0 1.1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR67512.1 - 2e-08 33.9 0.0 2.8e-07 30.1 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EMR67512.1 - 1.1e-05 24.6 0.3 2.1e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMR67512.1 - 0.0081 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR67512.1 - 0.048 13.6 3.2 0.09 12.7 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family CytB6-F_Fe-S PF08802.10 EMR67513.1 - 0.81 9.8 4.9 8.7 6.5 0.3 2.9 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit PHO4 PF01384.20 EMR67513.1 - 2.3 7.2 7.3 11 5.0 7.3 1.9 1 1 0 1 1 1 0 Phosphate transporter family DUF3488 PF11992.8 EMR67513.1 - 2.3 7.1 10.2 0.62 9.0 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) PSII_BNR PF14870.6 EMR67514.1 - 2.9e-08 33.3 7.8 2.2e-05 23.9 0.2 3.7 1 1 2 4 4 4 2 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 EMR67514.1 - 2.6e-06 26.5 1.6 0.00085 18.2 0.0 2.6 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 EMR67514.1 - 6.9e-05 22.3 26.1 0.26 11.4 0.9 6.4 6 0 0 6 6 6 5 BNR/Asp-box repeat BNR_2 PF13088.6 EMR67514.1 - 0.29 10.4 2.8 16 4.7 0.0 3.2 2 1 0 3 3 3 0 BNR repeat-like domain p450 PF00067.22 EMR67515.1 - 1.9e-49 168.7 0.0 2.8e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_20 PF00982.21 EMR67516.1 - 1.4e-197 657.1 0.0 1.7e-197 656.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EMR67516.1 - 0.025 14.3 0.5 0.081 12.6 0.3 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EMR67516.1 - 0.073 12.6 0.1 1.9 8.0 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 IBR PF01485.21 EMR67517.1 - 5.8e-15 55.3 13.7 2.9e-07 30.6 3.3 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 EMR67517.1 - 0.0013 18.8 3.5 0.0013 18.8 3.5 2.4 2 0 0 2 2 2 1 AN1-like Zinc finger Atg14 PF10186.9 EMR67517.1 - 0.21 10.6 7.6 0.28 10.2 7.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Transp_Tc5_C PF04236.15 EMR67517.1 - 0.22 11.9 8.9 2.3 8.7 1.4 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Folliculin PF11704.8 EMR67517.1 - 0.45 10.4 5.5 0.78 9.6 5.5 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Borrelia_P83 PF05262.11 EMR67517.1 - 1.5 7.2 10.5 1.7 7.0 10.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.19 EMR67517.1 - 2.2 6.1 3.6 2.5 5.9 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 EMR67517.1 - 2.7 8.5 21.7 4.4 7.8 21.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region RR_TM4-6 PF06459.12 EMR67517.1 - 3 7.6 7.6 4.1 7.2 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4449 PF14613.6 EMR67517.1 - 4.3 7.4 8.5 6.4 6.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) MRP-S26 PF14943.6 EMR67517.1 - 8.1 6.3 19.5 11 5.9 19.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Perilipin PF03036.16 EMR67517.1 - 9.9 5.1 8.0 13 4.7 8.0 1.0 1 0 0 1 1 1 0 Perilipin family CENP-T_C PF15511.6 EMR67518.1 - 1.7e-33 115.0 0.0 6.9e-33 113.0 0.0 2.0 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EMR67518.1 - 2.1e-08 34.4 0.1 4.3e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EMR67518.1 - 6e-05 23.4 0.0 6e-05 23.4 0.0 2.2 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EMR67518.1 - 0.00065 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EMR67518.1 - 0.074 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated dsDNA_bind PF01984.20 EMR67519.1 - 6.2e-33 113.4 10.8 7.5e-33 113.1 10.8 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.6 EMR67519.1 - 0.072 13.7 1.6 0.094 13.3 0.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) Sas10_Utp3 PF04000.15 EMR67520.1 - 3.1e-16 59.8 0.3 3.1e-16 59.8 0.3 2.5 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Nucleo_P87 PF07267.11 EMR67520.1 - 0.0056 15.6 4.1 0.0064 15.4 4.1 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 SUIM_assoc PF16619.5 EMR67520.1 - 0.017 15.2 1.0 0.017 15.2 1.0 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Glypican PF01153.19 EMR67520.1 - 0.55 9.0 6.1 0.69 8.7 6.1 1.1 1 0 0 1 1 1 0 Glypican DUF2052 PF09747.9 EMR67520.1 - 0.79 9.8 10.3 0.98 9.5 10.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4604 PF15377.6 EMR67520.1 - 0.98 9.8 24.5 1.2 9.5 24.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Neur_chan_memb PF02932.16 EMR67520.1 - 4 7.4 4.7 4.8 7.2 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.22 EMR67521.1 - 6.5e-54 181.9 0.0 7.5e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR67521.1 - 2e-21 76.5 0.0 2.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR67521.1 - 1.9e-06 27.5 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RdRP PF05183.12 EMR67522.1 - 9e-181 602.5 0.0 1.4e-180 601.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3861 PF12977.7 EMR67522.1 - 0.063 13.4 0.0 4 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) Peptidase_M78 PF06114.13 EMR67522.1 - 0.13 12.2 0.2 0.34 10.9 0.2 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain ApbA_C PF08546.11 EMR67523.1 - 1.9e-14 53.9 0.0 6.2e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EMR67523.1 - 1.6e-06 27.8 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Coq4 PF05019.13 EMR67524.1 - 9e-72 241.0 0.0 1e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 UBX PF00789.20 EMR67525.1 - 4.8e-09 36.3 0.0 1.1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 UBX domain SOBP PF15279.6 EMR67525.1 - 0.56 10.8 30.0 0.062 13.9 13.0 2.1 1 1 2 3 3 3 0 Sine oculis-binding protein DUF2076 PF09849.9 EMR67527.1 - 3e-06 27.5 25.0 6.1e-06 26.5 25.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EMR67527.1 - 0.00042 20.4 5.1 0.00065 19.8 5.1 1.3 1 0 0 1 1 1 1 CHCH domain Trypan_glycop_C PF10659.9 EMR67527.1 - 0.0089 16.4 6.2 0.014 15.8 6.2 1.2 1 0 0 1 1 1 1 Trypanosome variant surface glycoprotein C-terminal domain GCK PF07802.11 EMR67527.1 - 0.01 16.3 0.7 0.019 15.4 0.7 1.5 1 1 0 1 1 1 0 GCK domain YjbE PF11106.8 EMR67527.1 - 0.76 10.0 8.5 1.6 9.0 8.5 1.6 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE CX9C PF16860.5 EMR67527.1 - 1.3 9.1 10.3 0.27 11.3 6.0 1.9 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SURF1 PF02104.15 EMR67528.1 - 7.5e-44 150.1 0.1 1.1e-43 149.5 0.1 1.2 1 0 0 1 1 1 1 SURF1 family RE_TdeIII PF09520.10 EMR67529.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII NmrA PF05368.13 EMR67531.1 - 5.8e-45 153.7 0.3 7.2e-45 153.4 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR67531.1 - 1.1e-09 38.5 0.2 1.5e-09 38.0 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMR67531.1 - 0.00053 20.2 0.3 0.42 10.9 0.3 2.5 2 1 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EMR67531.1 - 0.0021 17.1 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Melibiase_2 PF16499.5 EMR67532.1 - 1.5e-35 122.7 3.8 2.9e-22 79.2 0.6 2.4 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 EMR67532.1 - 4e-10 39.6 0.6 4e-10 39.6 0.6 2.0 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain UCH PF00443.29 EMR67534.1 - 2.6e-20 73.0 0.0 3.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMR67534.1 - 0.0046 16.6 0.0 0.0088 15.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_pol_E_B PF04042.16 EMR67535.1 - 3.3e-11 43.0 0.0 3.8e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B COMPASS-Shg1 PF05205.12 EMR67536.1 - 9.8e-26 90.4 0.2 9.8e-26 90.4 0.2 2.9 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Rep_fac-A_3 PF08661.11 EMR67537.1 - 3.7e-20 72.2 0.0 4e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 HAD_2 PF13419.6 EMR67538.1 - 2.6e-08 34.1 0.0 5e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR67538.1 - 9.9e-06 25.5 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EMR67538.1 - 8.6e-05 22.9 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Dak1 PF02733.17 EMR67540.1 - 7.4e-106 353.5 2.9 9.4e-106 353.2 2.9 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EMR67540.1 - 4.6e-46 156.9 0.3 8.6e-46 156.0 0.3 1.5 1 0 0 1 1 1 1 DAK2 domain Antiterm PF03589.13 EMR67540.1 - 0.041 14.2 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 Antitermination protein MFAP1 PF06991.11 EMR67541.1 - 6.7e-71 238.6 28.8 6.7e-71 238.6 28.8 2.2 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Cwf_Cwc_15 PF04889.12 EMR67541.1 - 0.0049 16.7 23.5 0.0049 16.7 23.5 3.1 2 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein TPR_12 PF13424.6 EMR67542.1 - 7.3e-13 48.6 7.7 3.2e-06 27.3 0.0 4.1 1 1 3 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.22 EMR67542.1 - 4e-11 42.6 0.0 2.8e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 EMR67542.1 - 2.1e-07 30.6 9.6 0.0021 17.9 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat AAA_16 PF13191.6 EMR67542.1 - 9.1e-05 22.9 0.5 0.00051 20.5 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain TPR_2 PF07719.17 EMR67542.1 - 0.0085 16.1 10.2 17 5.8 0.5 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 EMR67542.1 - 0.046 14.0 0.0 0.31 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain TPR_8 PF13181.6 EMR67542.1 - 0.077 13.3 2.1 7.5 7.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Toprim PF01751.22 EMR67542.1 - 0.093 13.0 0.0 0.33 11.2 0.0 2.0 1 0 0 1 1 1 0 Toprim domain TPR_4 PF07721.14 EMR67542.1 - 0.11 13.2 3.7 5.7 7.9 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMR67542.1 - 0.15 12.0 5.0 5 7.1 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Dehydratase_LU PF02286.15 EMR67542.1 - 0.16 10.5 0.5 0.31 9.6 0.1 1.6 2 0 0 2 2 2 0 Dehydratase large subunit TPR_16 PF13432.6 EMR67542.1 - 0.23 12.1 7.5 3.6 8.3 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR67542.1 - 1.3 10.0 7.7 11 7.2 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Dicty_REP PF05086.12 EMR67543.1 - 0.087 10.8 1.3 0.12 10.4 1.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SDA1 PF05285.12 EMR67543.1 - 0.13 11.7 6.0 0.22 10.9 6.0 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EMR67543.1 - 4.4 5.3 9.3 5.9 4.9 9.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EMR67543.1 - 5.2 6.1 9.0 8.1 5.5 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Zn_clus PF00172.18 EMR67544.1 - 6.5e-09 35.8 11.8 1e-08 35.2 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMR67544.1 - 7.6e-07 28.3 0.3 1.4e-06 27.4 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain bZIP_1 PF00170.21 EMR67545.1 - 3.3e-09 36.7 14.4 3.3e-09 36.7 14.4 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EMR67545.1 - 2.7e-08 33.8 16.1 2.7e-08 33.8 16.1 2.6 2 1 1 3 3 3 1 Basic region leucine zipper FapA PF03961.13 EMR67545.1 - 0.7 8.4 4.6 0.97 8.0 4.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SR-25 PF10500.9 EMR67545.1 - 1.2 8.7 26.5 2 8.0 2.3 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Seryl_tRNA_N PF02403.22 EMR67545.1 - 5.4 7.3 18.1 11 6.3 18.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 EMR67545.1 - 8.2 5.7 14.4 13 5.0 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EMR67545.1 - 9.1 6.1 19.8 1.2 8.9 3.0 2.6 2 0 0 2 2 2 0 Septum formation initiator TPT PF03151.16 EMR67546.1 - 2.8e-13 49.9 14.0 3.7e-13 49.5 14.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family IF-2B PF01008.17 EMR67547.1 - 3.9e-48 164.1 0.0 1.1e-47 162.6 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Macoilin PF09726.9 EMR67547.1 - 0.59 8.6 4.2 0.84 8.1 4.2 1.1 1 0 0 1 1 1 0 Macoilin family PBP PF01161.20 EMR67548.1 - 6.3e-07 29.8 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RskA PF10099.9 EMR67548.1 - 0.014 15.7 6.4 0.026 14.8 6.4 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CAP_N PF01213.19 EMR67548.1 - 1.4 8.3 8.8 2.8 7.3 8.8 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal LSM PF01423.22 EMR67549.1 - 1.3e-12 47.2 0.0 1.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EMR67549.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Alb1 PF09135.11 EMR67551.1 - 2.3e-30 105.6 7.2 2.3e-30 105.6 7.2 1.8 2 0 0 2 2 2 1 Alb1 Ribosomal_L4 PF00573.22 EMR67552.1 - 1.7e-47 161.6 0.0 2.3e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_2 PF16113.5 EMR67553.1 - 1.9e-128 428.7 0.0 2.3e-128 428.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EMR67553.1 - 6.4e-30 104.3 0.2 2.5e-27 95.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase SPRY PF00622.28 EMR67554.1 - 1.1e-20 73.9 0.0 1.5e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 SPRY domain SET PF00856.28 EMR67555.1 - 8.7e-10 39.2 0.0 1.6e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 SET domain TPR_MalT PF17874.1 EMR67555.1 - 0.017 14.5 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 MalT-like TPR region Condensation PF00668.20 EMR67556.1 - 1.3e-19 70.2 0.0 1.4e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Condensation domain Ribophorin_I PF04597.14 EMR67558.1 - 6.9e-127 424.3 2.5 7.9e-127 424.1 2.5 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.16 EMR67559.1 - 1e-83 280.4 0.0 1.4e-83 280.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EMR67559.1 - 3.6e-72 242.4 0.0 7.3e-72 241.5 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Complex1_49kDa PF00346.19 EMR67561.1 - 1.9e-121 404.3 0.0 3.2e-121 403.6 0.0 1.4 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EMR67561.1 - 0.039 12.9 0.0 0.07 12.0 0.0 1.4 1 1 0 1 1 1 0 Nickel-dependent hydrogenase Maff2 PF12750.7 EMR67561.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Maff2 family SSF PF00474.17 EMR67562.1 - 5.4e-09 35.4 17.0 7.9e-09 34.9 17.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Methyltransf_30 PF05430.11 EMR67562.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase ARL6IP6 PF15062.6 EMR67562.1 - 0.23 11.6 1.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix FbpA PF05833.11 EMR67563.1 - 0.032 13.0 0.0 0.038 12.7 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) adh_short_C2 PF13561.6 EMR67564.1 - 2.2e-54 184.5 0.2 3.2e-54 183.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR67564.1 - 1.3e-46 158.6 2.0 1.6e-46 158.3 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR67564.1 - 4.6e-14 52.7 0.7 6.5e-14 52.2 0.7 1.1 1 0 0 1 1 1 1 KR domain Osteopontin PF00865.18 EMR67567.1 - 0.16 11.5 3.3 0.27 10.7 3.3 1.3 1 0 0 1 1 1 0 Osteopontin F-box PF00646.33 EMR67568.1 - 9.6e-05 22.2 0.1 0.00028 20.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain Ubie_methyltran PF01209.18 EMR67568.1 - 0.051 12.9 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family LRR_4 PF12799.7 EMR67568.1 - 0.091 13.2 2.7 11 6.6 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Peptidase_M28 PF04389.17 EMR67569.1 - 2.8e-28 99.0 0.0 4e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EMR67569.1 - 8.6e-08 32.1 0.0 5.5e-07 29.5 0.0 2.2 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 Pectate_lyase_3 PF12708.7 EMR67570.1 - 1.8e-72 243.7 15.6 8.5e-67 225.1 7.0 3.1 3 0 0 3 3 3 2 Pectate lyase superfamily protein VTC PF09359.10 EMR67571.1 - 1.4e-97 326.4 0.3 2.6e-97 325.5 0.3 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EMR67571.1 - 1.9e-13 51.1 12.7 1.3e-07 31.9 2.3 3.6 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.15 EMR67571.1 - 9.1e-13 48.5 1.3 1.6e-12 47.7 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Host_attach PF10116.9 EMR67571.1 - 0.03 14.9 0.1 0.086 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein required for attachment to host cells DUF3246 PF11596.8 EMR67571.1 - 0.047 13.1 1.3 0.075 12.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) baeRF_family12 PF18856.1 EMR67571.1 - 0.1 13.2 0.1 0.34 11.5 0.1 1.9 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 FixQ PF05545.11 EMR67571.1 - 0.15 12.0 0.2 0.41 10.7 0.2 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Pil1 PF13805.6 EMR67572.1 - 5e-110 367.2 5.3 7.6e-110 366.6 5.3 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 FAD_binding_3 PF01494.19 EMR67572.1 - 2.1e-23 83.2 0.1 4.6e-21 75.5 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EMR67572.1 - 3.8e-06 26.2 0.2 0.0042 16.2 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EMR67572.1 - 0.002 17.4 0.0 0.0034 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR67572.1 - 0.0083 15.7 0.0 0.37 10.3 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR67572.1 - 0.012 15.6 0.1 0.052 13.5 0.0 2.1 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMR67572.1 - 0.056 13.7 0.3 0.21 11.9 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EMR67572.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EMR67572.1 - 0.12 11.6 0.0 0.42 9.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family SE PF08491.10 EMR67572.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase AAA PF00004.29 EMR67574.1 - 4.1e-07 30.5 0.1 1.6e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Aspzincin_M35 PF14521.6 EMR67576.1 - 0.015 15.8 0.0 0.023 15.3 0.0 1.3 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase DUF3405 PF11885.8 EMR67577.1 - 6e-205 681.7 9.9 8.1e-204 678.0 9.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) TMEM100 PF16311.5 EMR67578.1 - 3 7.4 4.5 6.7 6.3 4.5 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 AFG1_ATPase PF03969.16 EMR67579.1 - 1.1e-71 241.6 0.0 3.2e-67 227.0 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase LigB PF02900.18 EMR67580.1 - 1.2e-24 86.8 0.0 1.6e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.16 EMR67581.1 - 4.4e-26 91.6 33.0 5.9e-26 91.2 33.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3775 PF12616.8 EMR67581.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Ank_2 PF12796.7 EMR67582.1 - 0.11 13.2 0.0 0.46 11.1 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) ketoacyl-synt PF00109.26 EMR67583.1 - 1.2e-43 149.5 0.0 1.7e-34 119.6 0.0 2.1 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR67583.1 - 9.3e-30 103.1 0.1 2.5e-29 101.7 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain MF_alpha_N PF05436.11 EMR67585.1 - 0.18 11.8 0.2 0.37 10.7 0.1 1.6 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Pkinase_Tyr PF07714.17 EMR67586.1 - 0.24 10.6 0.0 5.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Amidase PF01425.21 EMR67587.1 - 8.7e-55 186.5 0.2 1.9e-52 178.7 0.1 2.1 2 0 0 2 2 2 2 Amidase MFS_1 PF07690.16 EMR67588.1 - 2.4e-09 36.6 21.2 4.8e-09 35.6 21.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR67588.1 - 1.4e-06 28.1 4.7 1.4e-06 28.1 4.7 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EMR67589.1 - 3.3e-14 52.6 29.4 2.9e-13 49.5 9.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.19 EMR67590.1 - 2.5e-12 46.0 0.1 1.4e-11 43.6 0.0 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMR67590.1 - 1.2e-11 44.7 0.0 1.1e-10 41.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR67590.1 - 2e-09 37.1 0.1 1.7e-08 34.1 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR67590.1 - 4.7e-09 35.9 0.0 1.4e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR67590.1 - 3.2e-06 26.5 0.0 4.5e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EMR67590.1 - 7.8e-05 22.4 2.9 0.008 15.8 2.9 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR67590.1 - 0.00011 21.5 0.3 0.00027 20.3 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.15 EMR67590.1 - 0.00057 18.6 1.0 0.4 9.2 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 EMR67590.1 - 0.00088 19.3 0.1 0.38 10.7 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMR67590.1 - 0.052 14.1 1.0 15 6.2 0.3 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR67590.1 - 0.4 9.9 0.8 0.78 8.9 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain Bac_luciferase PF00296.20 EMR67591.1 - 9e-61 206.0 0.6 1.3e-60 205.5 0.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase TPD PF14811.6 EMR67593.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif HTH_25 PF13413.6 EMR67593.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Bac_luciferase PF00296.20 EMR67594.1 - 1.4e-58 198.8 2.5 1.8e-58 198.4 2.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fe_dep_repress PF01325.19 EMR67594.1 - 0.19 11.9 0.3 0.45 10.8 0.3 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain AAA_23 PF13476.6 EMR67595.1 - 3.1e-29 102.9 1.0 3.1e-29 102.9 1.0 8.0 1 1 5 7 7 2 1 AAA domain SbcCD_C PF13558.6 EMR67595.1 - 9e-07 29.0 0.0 3.2e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EMR67595.1 - 9.6e-07 28.8 28.4 1.1e-05 25.4 0.8 6.0 1 1 3 4 4 2 2 AAA ATPase domain AAA_21 PF13304.6 EMR67595.1 - 1e-06 28.8 20.9 0.0031 17.4 0.0 4.4 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMR67595.1 - 0.0015 18.2 0.3 0.0071 16.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain Snapin_Pallidin PF14712.6 EMR67595.1 - 0.0089 16.4 4.4 0.0089 16.4 4.4 10.1 7 3 3 11 11 10 3 Snapin/Pallidin AAA_16 PF13191.6 EMR67595.1 - 0.061 13.7 0.0 0.061 13.7 0.0 5.2 2 1 0 2 2 1 0 AAA ATPase domain ABC_tran PF00005.27 EMR67595.1 - 0.13 12.8 0.0 0.13 12.8 0.0 7.8 3 2 1 5 5 3 0 ABC transporter AAA_33 PF13671.6 EMR67595.1 - 0.52 10.5 0.0 0.52 10.5 0.0 4.1 5 0 0 5 5 5 0 AAA domain AAA_22 PF13401.6 EMR67595.1 - 2.3 8.5 10.3 0.5 10.6 0.1 4.8 3 2 0 3 3 3 0 AAA domain Flagellin_C PF00700.21 EMR67595.1 - 4.8 7.6 12.8 3 8.3 1.2 5.4 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region SURF2 PF05477.11 EMR67596.1 - 1 9.0 5.8 1.3 8.7 5.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Glyco_hydro_115 PF15979.5 EMR67597.1 - 2.3e-103 346.2 0.6 3.5e-103 345.6 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EMR67597.1 - 1.1e-54 184.8 0.0 1.8e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain S_layer_C PF05124.12 EMR67597.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 S-layer like family, C-terminal region GATA PF00320.27 EMR67598.1 - 6e-16 57.8 5.4 1.1e-15 57.0 5.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 EMR67598.1 - 8.5e-11 42.0 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 EMR67598.1 - 1.4e-06 28.4 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EMR67598.1 - 2.1e-06 27.7 0.1 9.2e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EMR67598.1 - 0.0024 18.1 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF1635 PF07795.11 EMR67598.1 - 0.0083 16.0 2.1 0.02 14.7 2.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) Zn-ribbon_8 PF09723.10 EMR67598.1 - 0.01 15.9 0.2 0.022 14.9 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Inj_translocase PF16928.5 EMR67598.1 - 0.026 14.0 0.6 0.045 13.2 0.6 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome PAS_9 PF13426.7 EMR67598.1 - 0.06 13.6 0.2 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 PAS domain INO80_Ies4 PF08193.11 EMR67598.1 - 0.084 12.9 9.1 0.25 11.3 1.7 2.2 2 0 0 2 2 2 0 INO80 complex subunit Ies4 TF_Zn_Ribbon PF08271.12 EMR67598.1 - 0.19 11.3 0.7 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding SUIM_assoc PF16619.5 EMR67598.1 - 1.8 8.7 7.4 0.42 10.7 2.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4428 PF14471.6 EMR67598.1 - 4.5 7.3 5.0 0.93 9.5 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) HET PF06985.11 EMR67600.1 - 5.4e-29 101.4 0.0 8e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Adenyl_transf PF04439.12 EMR67600.1 - 0.29 10.2 0.5 0.43 9.6 0.5 1.1 1 0 0 1 1 1 0 Streptomycin adenylyltransferase DUF829 PF05705.14 EMR67601.1 - 6.6e-42 144.1 0.2 8.1e-42 143.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ish1 PF10281.9 EMR67602.1 - 1.6e-83 274.7 28.5 5.3e-15 55.4 0.1 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EMR67602.1 - 3.8e-08 32.9 0.0 14 5.6 0.0 8.0 9 0 0 9 9 9 1 SAP domain HeH PF12949.7 EMR67602.1 - 3.3e-05 23.5 0.1 1.4 8.6 0.0 4.9 5 0 0 5 5 5 1 HeH/LEM domain Slx4 PF09494.10 EMR67602.1 - 8.2e-05 22.5 1.5 35 4.4 0.0 6.0 6 1 0 6 6 6 0 Slx4 endonuclease TubC_N PF18563.1 EMR67602.1 - 0.0056 16.6 0.3 0.027 14.4 0.1 2.2 2 0 0 2 2 2 1 TubC N-terminal docking domain Phage_CRI PF05144.14 EMR67602.1 - 0.069 12.5 0.2 0.069 12.5 0.2 2.0 2 0 0 2 2 2 0 Phage replication protein CRI CyRPA PF18638.1 EMR67602.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Cysteine-Rich Protective Antigen 6 bladed domain SAM_2 PF07647.17 EMR67602.1 - 0.12 12.5 1.4 2.3 8.4 0.1 3.5 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) 6PGD PF00393.19 EMR67602.1 - 0.95 8.8 8.2 4.8 6.5 0.1 3.9 2 1 2 4 4 4 0 6-phosphogluconate dehydrogenase, C-terminal domain Apolipoprotein PF01442.18 EMR67602.1 - 1.6 8.6 11.1 2.7 7.8 0.0 4.0 3 1 1 4 4 4 0 Apolipoprotein A1/A4/E domain CinA PF02464.17 EMR67603.1 - 5.1e-34 117.1 2.8 1.2e-33 115.8 2.8 1.6 1 1 0 1 1 1 1 Competence-damaged protein UPF0254 PF06787.11 EMR67603.1 - 0.094 12.5 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Rhabdo_ncap PF00945.18 EMR67604.1 - 3.6 6.4 4.9 6.2 5.6 4.9 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF4360 PF14273.6 EMR67605.1 - 3.1e-47 160.7 0.0 3.6e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Glyco_hydro_7 PF00840.20 EMR67607.1 - 1.2e-184 614.1 9.3 1.4e-184 613.9 9.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 NAD_binding_8 PF13450.6 EMR67607.1 - 0.08 13.2 0.0 0.42 10.9 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Methyltransf_11 PF08241.12 EMR67608.1 - 4.9e-21 75.2 0.0 9.8e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR67608.1 - 1.9e-20 73.2 0.0 2.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR67608.1 - 2.3e-19 69.9 0.1 5.2e-19 68.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR67608.1 - 1.6e-15 57.1 0.0 2.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EMR67608.1 - 2e-14 53.7 0.0 3.1e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR67608.1 - 3.8e-13 50.0 0.0 5.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR67608.1 - 0.00055 19.5 0.0 0.0015 18.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_29 PF03141.16 EMR67608.1 - 0.0029 16.2 0.1 0.0037 15.9 0.1 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 EMR67608.1 - 0.039 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EMR67608.1 - 0.061 13.3 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EMR67608.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CheR PF01739.18 EMR67608.1 - 0.2 11.1 0.0 0.56 9.7 0.0 1.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain adh_short PF00106.25 EMR67609.1 - 1.4e-29 103.0 0.0 1.8e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67609.1 - 2.4e-22 79.6 0.0 2.9e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67609.1 - 1.4e-08 34.9 0.0 2.1e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR67609.1 - 0.0095 15.8 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EMR67609.1 - 0.058 12.8 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Hydrophobin_2 PF06766.11 EMR67611.1 - 2.1e-27 94.8 9.3 3.4e-27 94.2 9.3 1.3 1 0 0 1 1 1 1 Fungal hydrophobin LRR_8 PF13855.6 EMR67612.1 - 0.0036 17.0 1.2 0.008 15.9 0.4 2.0 2 1 0 2 2 2 1 Leucine rich repeat Recep_L_domain PF01030.24 EMR67612.1 - 0.039 14.1 0.6 0.1 12.7 0.5 1.8 1 1 0 1 1 1 0 Receptor L domain Glyco_hydro_35 PF01301.19 EMR67613.1 - 7.6e-77 259.0 0.0 5.4e-76 256.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EMR67613.1 - 0.00051 19.5 0.0 0.002 17.6 0.0 1.9 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 EMR67613.1 - 0.0017 18.9 0.1 0.31 11.6 0.0 3.1 3 1 0 3 3 3 1 Beta-galactosidase jelly roll domain ALF PF03752.13 EMR67613.1 - 0.75 9.8 3.6 2.6 8.1 3.6 1.9 1 0 0 1 1 1 0 Short repeats of unknown function Kinesin PF00225.23 EMR67614.1 - 2.5e-56 191.0 0.0 4.7e-56 190.1 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMR67614.1 - 5.1e-10 39.5 0.0 2.9e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding EzrA PF06160.12 EMR67614.1 - 0.2 9.8 0.8 0.3 9.2 0.8 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NRBF2 PF08961.10 EMR67614.1 - 0.72 9.4 4.6 9.1 5.8 0.7 2.6 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator FAM76 PF16046.5 EMR67614.1 - 0.77 9.1 3.1 0.46 9.8 0.6 1.7 2 0 0 2 2 2 0 FAM76 protein TFIIA PF03153.13 EMR67614.1 - 1.7 8.6 5.6 0.15 12.0 1.0 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GST_N_2 PF13409.6 EMR67615.1 - 1e-07 32.1 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR67615.1 - 5e-07 30.0 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMR67615.1 - 1.4e-06 28.5 0.0 2.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR67615.1 - 2.1e-05 24.6 0.0 3e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR67615.1 - 4.3e-05 23.5 0.1 0.00012 22.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR67615.1 - 0.0001 22.4 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GDPD_2 PF13653.6 EMR67616.1 - 0.012 16.1 0.1 0.029 14.8 0.1 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family SH3_9 PF14604.6 EMR67617.1 - 0.043 13.7 0.0 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Variant SH3 domain DUF3805 PF12712.7 EMR67617.1 - 0.21 11.7 0.5 0.39 10.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3805) FAD_binding_4 PF01565.23 EMR67619.1 - 2.6e-25 88.8 7.9 3.3e-23 82.0 6.2 2.7 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.12 EMR67619.1 - 0.00012 22.1 0.1 0.00034 20.7 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_31 PF01055.26 EMR67620.1 - 5.3e-106 355.4 0.5 7.7e-106 354.9 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EMR67620.1 - 1.4e-06 28.5 1.1 9.4e-06 25.9 0.1 2.7 2 1 0 2 2 2 1 Galactose mutarotase-like Fungal_trans PF04082.18 EMR67621.1 - 0.00095 18.3 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 EMR67623.1 - 1.7e-12 47.4 0.0 2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR67623.1 - 2e-09 37.6 0.1 3.1e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_trans_4_4 PF13579.6 EMR67623.1 - 0.0039 17.6 2.7 0.019 15.4 0.1 2.8 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain NAD_binding_7 PF13241.6 EMR67623.1 - 0.0053 17.2 0.0 0.035 14.5 0.0 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding Epimerase PF01370.21 EMR67623.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Phage_cap_E PF03864.15 EMR67623.1 - 0.045 12.9 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Phage major capsid protein E F420_oxidored PF03807.17 EMR67623.1 - 0.13 12.9 0.2 0.39 11.3 0.0 1.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Uma2 PF05685.12 EMR67624.1 - 0.019 14.5 0.1 0.029 13.9 0.1 1.3 1 1 0 1 1 1 0 Putative restriction endonuclease Asp PF00026.23 EMR67625.1 - 1.1e-08 34.9 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 EMR67625.1 - 5.8e-07 28.8 4.1 1e-06 28.0 4.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 EMR67625.1 - 0.0013 18.9 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.7 EMR67625.1 - 0.016 14.7 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Peptidase_M43 PF05572.13 EMR67627.1 - 1.1e-11 44.8 3.0 1.8e-11 44.2 1.2 1.9 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EMR67627.1 - 0.00013 22.1 0.2 0.0002 21.6 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EMR67627.1 - 0.00073 19.2 0.2 0.00093 18.9 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EMR67627.1 - 0.0018 18.1 0.2 0.0049 16.7 0.2 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 EMR67627.1 - 0.006 17.1 0.1 0.012 16.1 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like NOA36 PF06524.12 EMR67628.1 - 0.012 15.0 0.4 0.013 14.9 0.4 1.1 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 EMR67628.1 - 8.6 5.3 11.4 4.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Pes-10 Peptidase_S10 PF00450.22 EMR67629.1 - 3.1e-78 264.1 0.0 4e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase p450 PF00067.22 EMR67630.1 - 5.1e-40 137.6 0.0 3.7e-37 128.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 PI3_PI4_kinase PF00454.27 EMR67631.1 - 5.5e-41 141.0 0.0 3.2e-38 132.0 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EMR67631.1 - 1.5e-22 79.9 0.0 2.6e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EMR67631.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) FMO-like PF00743.19 EMR67632.1 - 2.7e-40 138.3 0.0 3.2e-19 68.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR67632.1 - 8.6e-22 77.8 0.1 1.5e-15 57.3 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR67632.1 - 7.7e-16 58.2 0.0 3.8e-15 55.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR67632.1 - 8e-11 41.9 0.3 0.00047 19.6 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 EMR67632.1 - 3.6e-09 36.7 7.6 9e-05 22.2 3.9 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EMR67632.1 - 5.6e-09 35.6 3.1 3.1e-07 29.9 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EMR67632.1 - 2e-08 34.3 0.2 1.1e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMR67632.1 - 6.7e-08 33.0 4.5 0.00025 21.5 0.6 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR67632.1 - 2e-07 31.1 5.2 0.00016 21.7 0.3 4.2 4 1 0 4 4 4 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EMR67632.1 - 1.2e-05 24.9 0.6 2.3e-05 24.0 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR67632.1 - 2.9e-05 23.4 2.5 0.00096 18.5 0.9 2.2 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EMR67632.1 - 5.9e-05 22.5 0.5 0.0033 16.7 0.2 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EMR67632.1 - 0.0001 22.3 0.5 0.65 10.0 0.3 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EMR67632.1 - 0.00081 18.6 1.7 0.00081 18.6 1.7 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EMR67632.1 - 0.0014 17.8 3.9 0.0061 15.7 2.0 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EMR67632.1 - 0.012 14.3 4.4 0.023 13.4 1.4 2.6 3 0 0 3 3 3 0 HI0933-like protein 3HCDH_N PF02737.18 EMR67632.1 - 0.023 14.6 1.9 0.17 11.8 1.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EMR67632.1 - 0.036 13.3 3.0 0.045 13.0 0.8 2.2 3 0 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 EMR67632.1 - 0.05 14.1 0.4 15 6.1 0.1 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 EMR67632.1 - 0.14 12.4 0.2 0.51 10.5 0.1 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EMR67632.1 - 0.21 11.2 1.2 3.7 7.1 0.4 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 EMR67632.1 - 0.23 10.8 0.9 6 6.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EMR67632.1 - 0.44 9.5 3.2 0.37 9.8 1.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein HSP20 PF00011.21 EMR67633.1 - 2.2e-18 66.3 0.1 2.4e-12 46.9 0.0 2.3 2 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EMR67633.1 - 0.00011 21.6 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Glyco_hydro_53 PF07745.13 EMR67634.1 - 1e-94 317.3 0.4 1.4e-94 316.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 TMEM51 PF15345.6 EMR67634.1 - 0.041 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Herpes_gE PF02480.16 EMR67634.1 - 0.056 12.2 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 EMR67634.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family CcmD PF04995.14 EMR67634.1 - 0.11 12.6 4.1 0.27 11.3 4.1 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Insulin_TMD PF17870.1 EMR67634.1 - 0.13 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 EMR67634.1 - 0.13 13.1 0.0 0.29 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 EMR67634.1 - 3.6 7.6 9.7 1.8 8.5 1.4 2.9 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DMRL_synthase PF00885.19 EMR67635.1 - 7.5e-57 191.1 0.0 1.1e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Polysacc_deac_1 PF01522.21 EMR67636.1 - 1.4e-20 73.4 0.0 2.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 EMR67636.1 - 0.002 17.3 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase GFRP PF06399.13 EMR67636.1 - 0.058 13.3 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) HTH_33 PF13592.6 EMR67636.1 - 0.13 11.9 0.9 6.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn helix DUF3080 PF11279.8 EMR67637.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Ribosomal_L34 PF00468.17 EMR67637.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L34 NmrA PF05368.13 EMR67638.1 - 4.7e-16 59.0 0.0 7.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR67638.1 - 9.1e-12 45.2 0.0 1.7e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR67638.1 - 1.1e-06 28.3 0.6 4e-05 23.2 0.2 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR67638.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EMR67638.1 - 0.013 16.1 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EMR67638.1 - 0.03 13.4 0.1 0.088 11.9 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.25 EMR67638.1 - 0.061 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 EMR67638.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_1 PF00175.21 EMR67639.1 - 1.5e-25 89.9 0.0 3.4e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMR67639.1 - 9.2e-08 32.4 0.0 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EMR67639.1 - 0.00011 22.5 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Glyco_hydro_17 PF00332.18 EMR67640.1 - 0.0074 15.9 2.0 0.01 15.4 0.1 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 HIT PF01230.23 EMR67641.1 - 1.4e-20 73.9 0.0 2.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EMR67641.1 - 0.015 15.8 0.0 6.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding SSP160 PF06933.11 EMR67641.1 - 0.27 9.4 7.9 0.35 9.0 7.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MSP1_C PF07462.11 EMR67641.1 - 1.7 7.3 3.0 2.1 6.9 3.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus 3Beta_HSD PF01073.19 EMR67642.1 - 3.8e-24 85.2 0.0 1.2e-23 83.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMR67642.1 - 2.2e-10 40.1 0.0 5.9e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EMR67642.1 - 3.4e-10 39.8 0.0 6.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR67642.1 - 1.4e-07 31.6 0.0 3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR67642.1 - 1.6e-06 27.5 0.0 2.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMR67642.1 - 0.00031 20.7 0.0 0.00075 19.4 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR67642.1 - 0.00089 18.7 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMR67642.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Polyketide_cyc2 PF10604.9 EMR67644.1 - 0.072 13.4 1.1 0.36 11.1 0.5 2.3 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport PQQ PF01011.21 EMR67644.1 - 0.55 10.3 2.8 0.99 9.5 1.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat Cys_Met_Meta_PP PF01053.20 EMR67645.1 - 6.6e-55 186.2 0.0 1.1e-53 182.1 0.0 2.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMR67645.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Cation_efflux PF01545.21 EMR67646.1 - 9.5e-24 84.2 12.0 1.2e-23 83.9 12.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMR67646.1 - 8.3e-06 25.8 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4271 PF14093.6 EMR67646.1 - 0.44 10.4 3.6 0.69 9.8 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Proteasome PF00227.26 EMR67647.1 - 2.2e-30 105.6 0.2 5.1e-30 104.4 0.1 1.6 2 1 0 2 2 2 1 Proteasome subunit Kinesin PF00225.23 EMR67648.1 - 6.2e-75 252.2 1.5 3.8e-74 249.6 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EMR67648.1 - 4.3e-41 140.3 0.0 1.1e-40 139.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Torsin PF06309.11 EMR67648.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA PF00004.29 EMR67649.1 - 9.3e-12 45.5 0.0 2.2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMR67649.1 - 2.4e-06 27.9 0.0 6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EMR67649.1 - 6.1e-05 23.0 0.1 0.00026 21.0 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 EMR67649.1 - 0.00023 21.2 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EMR67649.1 - 0.00023 21.2 0.0 0.00069 19.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EMR67649.1 - 0.00029 20.6 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMR67649.1 - 0.00081 19.8 0.1 0.0036 17.7 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 EMR67649.1 - 0.0015 18.7 0.3 0.009 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EMR67649.1 - 0.0021 17.4 0.7 0.054 12.8 0.1 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EMR67649.1 - 0.0067 16.2 1.1 0.015 15.0 0.2 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EMR67649.1 - 0.016 14.4 0.0 0.04 13.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Jun PF03957.13 EMR67649.1 - 0.017 15.1 0.5 1.6 8.6 0.1 2.8 3 0 0 3 3 3 0 Jun-like transcription factor AAA_19 PF13245.6 EMR67649.1 - 0.017 15.5 0.2 0.8 10.0 0.2 3.2 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EMR67649.1 - 0.018 15.0 0.3 0.17 11.8 0.0 2.4 2 1 1 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 EMR67649.1 - 0.046 13.2 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Methyltr_RsmB-F PF01189.17 EMR67649.1 - 0.047 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F NTPase_1 PF03266.15 EMR67649.1 - 0.05 13.5 0.6 0.34 10.8 0.1 2.4 2 1 0 2 2 2 0 NTPase AAA_8 PF12780.7 EMR67649.1 - 0.081 12.2 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA_18 PF13238.6 EMR67649.1 - 0.095 13.2 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMR67649.1 - 0.1 12.4 0.1 4.9 7.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EMR67649.1 - 0.12 12.7 0.1 0.34 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EMR67649.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EMR67649.1 - 0.3 10.8 1.4 0.71 9.6 0.1 2.2 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase Amidoligase_2 PF12224.8 EMR67650.1 - 6e-16 58.9 0.0 1.1e-13 51.4 0.0 2.5 3 0 0 3 3 3 2 Putative amidoligase enzyme NAF PF03822.14 EMR67650.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 NAF domain RXT2_N PF08595.11 EMR67651.1 - 0.29 11.1 5.1 0.29 11.1 1.2 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 EMR67651.1 - 3.1 7.5 10.7 2.7 7.6 6.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 EMR67651.1 - 6 6.5 10.8 1.1 9.0 1.7 3.3 4 0 0 4 4 4 0 FAM176 family ADH_zinc_N PF00107.26 EMR67654.1 - 2.6e-08 33.9 0.0 4.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR67654.1 - 0.0071 16.2 0.2 0.18 11.7 0.1 3.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 EMR67655.1 - 4.7e-41 141.0 0.0 5.6e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EMR67656.1 - 4e-36 124.7 46.5 2e-35 122.4 46.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR67656.1 - 9.8e-12 44.5 13.5 9.8e-12 44.5 13.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EMR67656.1 - 1.1e-08 34.0 13.9 1.7e-08 33.4 13.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.8 EMR67656.1 - 0.051 13.8 4.2 0.45 10.8 1.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) DUF1707 PF08044.11 EMR67657.1 - 0.089 12.9 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Transferase PF02458.15 EMR67658.1 - 6.4e-11 41.6 0.0 1.2e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 Transferase family ketoacyl-synt PF00109.26 EMR67659.1 - 1.5e-41 142.7 0.1 4.8e-41 141.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 EMR67659.1 - 1.8e-28 98.2 0.0 5.3e-28 96.7 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain NAD_binding_4 PF07993.12 EMR67659.1 - 1.9e-28 99.3 0.0 5.4e-28 97.9 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EMR67659.1 - 6.4e-19 68.1 0.1 1.6e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 EMR67659.1 - 3.7e-16 59.6 0.2 9.6e-14 51.7 0.5 2.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 EMR67659.1 - 2.6e-13 50.6 0.0 1.1e-12 48.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR67659.1 - 1.8e-12 47.4 0.7 2.2e-10 40.7 0.2 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EMR67659.1 - 3e-12 46.7 0.0 1e-11 44.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR67659.1 - 7.6e-12 45.8 0.0 5.2e-11 43.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR67659.1 - 1.3e-08 34.7 0.0 4.5e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR67659.1 - 2.1e-08 34.7 0.0 6.3e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EMR67659.1 - 3.7e-07 29.8 0.0 1.9e-06 27.5 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Acyl_transf_1 PF00698.21 EMR67659.1 - 4.8e-06 26.3 0.3 0.00021 20.9 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 EMR67659.1 - 0.0037 17.7 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension GDP_Man_Dehyd PF16363.5 EMR67659.1 - 0.05 13.0 0.1 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMR67659.1 - 0.055 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EMR67659.1 - 0.08 11.9 0.0 3.5 6.5 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EMR67659.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 KR domain FAD_binding_3 PF01494.19 EMR67660.1 - 1.2e-27 97.1 0.7 6.1e-26 91.5 0.7 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR67660.1 - 4e-06 26.6 4.5 8.1e-06 25.7 4.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR67660.1 - 0.00021 21.5 0.4 0.00076 19.7 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR67660.1 - 0.0013 18.1 0.5 0.003 16.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR67660.1 - 0.015 15.9 1.6 0.033 14.8 1.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RPAP1_N PF08621.10 EMR67660.1 - 0.026 14.3 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 RPAP1-like, N-terminal 3HCDH_N PF02737.18 EMR67660.1 - 0.13 12.1 0.7 0.21 11.5 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EMR67660.1 - 0.27 10.1 1.9 19 4.0 1.9 2.1 1 1 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 EMR67660.1 - 0.6 8.8 1.7 0.86 8.2 1.7 1.2 1 0 0 1 1 1 0 HI0933-like protein LIP PF03583.14 EMR67661.1 - 2.5e-57 194.4 0.1 3.5e-57 193.9 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase MFS_1 PF07690.16 EMR67662.1 - 4.1e-12 45.7 26.6 4.1e-12 45.7 26.6 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR67662.1 - 2.4e-10 39.5 0.8 2.4e-10 39.5 0.8 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2975 PF11188.8 EMR67662.1 - 0.018 14.9 5.8 0.16 11.8 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF2070 PF09843.9 EMR67662.1 - 2.2 6.5 3.8 2.9 6.1 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase PF00069.25 EMR67663.1 - 0.037 13.4 0.0 2.8 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein kinase domain ABC_tran PF00005.27 EMR67664.1 - 8.8e-34 117.0 0.0 1.7e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EMR67664.1 - 1.1e-07 31.8 4.7 1.8e-07 31.1 4.7 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.6 EMR67664.1 - 0.0014 18.9 0.0 0.0078 16.5 0.0 2.3 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EMR67664.1 - 0.0028 17.6 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 EMR67664.1 - 0.0046 17.4 0.3 0.15 12.5 0.1 2.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EMR67664.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EMR67664.1 - 0.017 15.5 0.0 0.043 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EMR67664.1 - 0.03 14.8 0.1 0.063 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMR67664.1 - 0.032 14.0 0.1 0.078 12.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EMR67664.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 EMR67664.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EMR67664.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EMR67664.1 - 0.063 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SMC_N PF02463.19 EMR67664.1 - 0.065 12.7 0.0 2.3 7.6 0.0 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMR67664.1 - 0.075 12.8 0.3 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EMR67664.1 - 0.11 12.6 0.1 0.36 10.9 0.1 1.9 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_15 PF13175.6 EMR67664.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EMR67664.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EMR67664.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Peptidase_M24 PF00557.24 EMR67665.1 - 4.2e-30 105.0 0.8 1.2e-24 87.2 0.2 2.1 1 1 1 2 2 2 2 Metallopeptidase family M24 zf-C6H2 PF15801.5 EMR67665.1 - 2.5e-09 37.3 4.9 2.5e-09 37.3 4.9 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EMR67665.1 - 0.034 14.3 2.6 0.034 14.3 2.6 2.0 2 0 0 2 2 2 0 MYND finger Isochorismatase PF00857.20 EMR67666.1 - 2.1e-12 47.6 0.0 2.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Gamma_PGA_hydro PF05908.11 EMR67666.1 - 0.027 13.9 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase Mur_ligase PF01225.25 EMR67666.1 - 0.094 13.1 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, catalytic domain adh_short PF00106.25 EMR67667.1 - 1.6e-36 125.6 0.1 1.9e-36 125.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67667.1 - 1.9e-26 93.1 0.0 2.2e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EMR67667.1 - 0.00022 21.2 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMR67667.1 - 0.00062 19.7 0.4 0.00098 19.1 0.4 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMR67667.1 - 0.00093 18.6 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMR67667.1 - 0.0024 17.4 0.1 0.0045 16.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DER1 PF04511.15 EMR67667.1 - 0.028 14.3 0.1 0.037 14.0 0.1 1.1 1 0 0 1 1 1 0 Der1-like family NmrA PF05368.13 EMR67667.1 - 0.053 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EMR67667.1 - 0.059 12.8 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PAE PF03283.13 EMR67667.1 - 0.16 11.1 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Peptidase_M24 PF00557.24 EMR67668.1 - 1.5e-34 119.5 0.1 2e-34 119.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3323 PF11796.8 EMR67668.1 - 0.09 12.7 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) PGA2 PF07543.12 EMR67668.1 - 9.3 6.2 7.4 2.7 8.0 3.0 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 GMC_oxred_N PF00732.19 EMR67669.1 - 2.1e-54 184.9 0.0 6.5e-54 183.3 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR67669.1 - 1.6e-33 116.3 0.0 3e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 EMR67669.1 - 2.7e-06 26.9 0.1 0.066 12.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR67669.1 - 3.6e-05 23.2 0.1 0.048 12.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR67669.1 - 6.2e-05 23.2 0.3 0.00031 20.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR67669.1 - 0.00011 21.9 0.3 0.00029 20.5 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR67669.1 - 0.0002 20.6 0.1 0.015 14.4 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EMR67669.1 - 0.0016 17.5 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EMR67669.1 - 0.0021 16.8 0.1 0.067 11.9 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 EMR67669.1 - 0.0059 15.9 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EMR67669.1 - 0.038 13.1 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A tRNA-Thr_ED PF08915.11 EMR67669.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Trp_halogenase PF04820.14 EMR67669.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase RTA1 PF04479.13 EMR67670.1 - 7.3e-66 221.7 13.3 7.3e-66 221.7 13.3 1.7 2 0 0 2 2 2 1 RTA1 like protein OppC_N PF12911.7 EMR67670.1 - 9.4 6.3 11.9 2.6 8.1 0.6 4.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C COX7B PF05392.11 EMR67671.1 - 0.042 13.5 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Glyco_hydro_3 PF00933.21 EMR67673.1 - 1.6e-36 126.3 0.0 2e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_transf_28 PF03033.20 EMR67674.1 - 2e-10 40.8 0.0 2e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EMR67674.1 - 5.9e-05 22.0 0.0 8.5e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EMR67674.1 - 0.0016 18.5 0.4 0.0033 17.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain HCV_capsid PF01543.17 EMR67674.1 - 0.0069 16.6 0.7 0.016 15.4 0.7 1.6 1 0 0 1 1 1 1 Hepatitis C virus capsid protein Pol_alpha_B_N PF08418.10 EMR67674.1 - 0.13 12.2 4.4 0.21 11.5 4.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Cas_Csy4 PF09618.10 EMR67674.1 - 0.16 12.1 3.6 0.27 11.4 3.6 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) SOG2 PF10428.9 EMR67674.1 - 1.2 8.2 10.5 1.7 7.8 10.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Nha1_C PF08619.10 EMR67674.1 - 1.5 7.9 12.5 3.5 6.7 12.2 1.6 1 1 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus MFS_1 PF07690.16 EMR67675.1 - 4.2e-09 35.8 8.8 6.1e-06 25.4 4.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 EMR67675.1 - 0.058 13.0 0.0 0.97 9.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) YoqO PF14037.6 EMR67675.1 - 0.082 13.4 2.0 1.1 9.8 0.3 2.4 2 0 0 2 2 2 0 YoqO-like protein Kinetochor_Ybp2 PF08568.10 EMR67677.1 - 6.8e-87 292.4 0.0 8.3e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin ATP-synt_I PF03899.15 EMR67677.1 - 0.2 12.1 0.6 0.41 11.1 0.0 1.8 2 0 0 2 2 2 0 ATP synthase I chain Pox_A12 PF04651.13 EMR67677.1 - 0.25 11.4 1.5 0.41 10.7 1.5 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein DUF3446 PF11928.8 EMR67677.1 - 0.84 10.0 8.3 3 8.2 4.3 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain R3H PF01424.22 EMR67678.1 - 2e-09 37.3 0.1 3.9e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 R3H domain Sugar_tr PF00083.24 EMR67679.1 - 3.8e-83 279.9 19.4 4.6e-83 279.6 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR67679.1 - 1.3e-16 60.5 44.7 2.3e-12 46.5 13.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 EMR67680.1 - 1.1e-11 45.1 0.0 0.0038 17.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR67680.1 - 1.1e-10 40.8 0.0 2.7 8.8 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EMR67680.1 - 6.8e-08 32.9 0.0 0.43 11.2 0.0 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR67680.1 - 1.6e-07 31.4 0.0 2.4 8.6 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EMR67680.1 - 4.2e-06 26.9 0.0 3.1 8.4 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat adh_short PF00106.25 EMR67681.1 - 2.8e-06 26.9 0.0 0.076 12.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase Tyrosinase PF00264.20 EMR67683.1 - 1.9e-44 152.6 0.0 2.7e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Pec_lyase_C PF00544.19 EMR67684.1 - 6.1e-38 130.5 5.3 9.2e-38 129.9 5.3 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EMR67684.1 - 6.5e-05 22.8 2.5 6.5e-05 22.8 2.5 2.5 2 1 1 3 3 3 2 Right handed beta helix region p450 PF00067.22 EMR67685.1 - 1.7e-58 198.5 0.0 2.3e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EMR67686.1 - 5.8e-75 252.8 0.0 6.7e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSA_C PF10479.9 EMR67687.1 - 1.7 6.7 11.6 1.8 6.6 11.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus REF PF05755.12 EMR67688.1 - 1 9.1 4.6 26 4.6 3.0 2.2 1 1 0 2 2 2 0 Rubber elongation factor protein (REF) Peptidase_M43 PF05572.13 EMR67689.1 - 4.7e-14 52.6 0.1 9.6e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EMR67689.1 - 0.0011 19.1 0.6 0.0021 18.3 0.6 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 EMR67689.1 - 0.003 16.5 0.1 0.0041 16.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 EMR67689.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EMR67689.1 - 0.0094 15.8 0.5 0.025 14.4 0.5 1.4 1 1 0 1 1 1 1 Matrixin DUF4953 PF16313.5 EMR67689.1 - 0.013 14.7 0.2 0.022 14.0 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 EMR67689.1 - 0.027 15.0 0.0 0.046 14.2 0.0 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EMR67689.1 - 0.028 14.3 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like QCR10 PF09796.9 EMR67690.1 - 1.3 9.1 7.8 2.1 8.4 0.1 3.9 3 1 1 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF872 PF05915.12 EMR67690.1 - 2.9 8.1 7.1 7 6.9 1.1 2.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) CBF PF03914.17 EMR67691.1 - 1.1e-51 175.2 0.2 1.1e-51 175.2 0.2 2.3 2 1 0 2 2 2 1 CBF/Mak21 family Cnd1 PF12717.7 EMR67691.1 - 0.0023 18.0 1.9 0.041 13.9 0.2 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 p450 PF00067.22 EMR67692.1 - 2.6e-49 168.2 0.0 3.2e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APS_kinase PF01583.20 EMR67693.1 - 2.9e-70 235.2 0.0 3.9e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EMR67693.1 - 6.7e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMR67693.1 - 0.00065 20.2 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMR67693.1 - 0.0037 16.7 0.0 0.0069 15.9 0.0 1.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Dmrt1 PF12374.8 EMR67693.1 - 0.099 13.1 0.3 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 AAA_29 PF13555.6 EMR67693.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EMR67693.1 - 0.11 12.9 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase TctC PF03401.14 EMR67693.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor FAD_binding_4 PF01565.23 EMR67694.1 - 2.5e-14 53.2 1.6 2.3e-13 50.1 1.6 2.3 1 1 0 1 1 1 1 FAD binding domain V-ATPase_C PF03223.15 EMR67695.1 - 1e-126 423.3 0.3 1.2e-126 423.1 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 EMR67695.1 - 0.059 14.0 0.3 0.17 12.5 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain AA_permease PF00324.21 EMR67697.1 - 3.3e-50 171.1 42.4 7e-46 156.8 35.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EMR67697.1 - 1.7e-06 27.1 32.2 1.7e-06 27.1 32.2 1.5 1 1 0 1 1 1 1 Amino acid permease Cpta_toxin PF07254.12 EMR67697.1 - 5.2 7.1 6.6 0.88 9.6 1.7 2.2 3 0 0 3 3 3 0 Membrane-bound toxin component of toxin-antitoxin system LPMO_10 PF03067.15 EMR67698.1 - 2.3e-14 54.5 0.9 2.3e-14 54.5 0.9 1.5 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Serglycin PF04360.12 EMR67698.1 - 8e-05 22.6 0.6 0.00015 21.8 0.6 1.4 1 0 0 1 1 1 1 Serglycin Glyco_hydro2_C5 PF18565.1 EMR67698.1 - 0.13 12.1 2.4 0.12 12.2 0.9 1.7 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 BAT2_N PF07001.11 EMR67698.1 - 2.1 8.8 10.0 0.24 11.8 5.5 1.7 2 0 0 2 2 2 0 BAT2 N-terminus Glyco_hydro_76 PF03663.14 EMR67699.1 - 3e-44 152.0 8.7 9.7e-44 150.4 8.7 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMR67699.1 - 3.6e-05 23.0 0.0 8.1e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 EMR67699.1 - 0.0061 16.1 0.1 0.1 12.1 0.0 2.8 3 1 1 4 4 4 1 D-glucuronyl C5-epimerase C-terminus peroxidase PF00141.23 EMR67701.1 - 1.6e-19 70.5 0.0 2.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Abhydrolase_6 PF12697.7 EMR67702.1 - 1.5e-12 48.6 3.8 2.9e-12 47.7 3.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR67702.1 - 7.8e-08 31.9 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR67702.1 - 1.5e-07 31.3 0.2 2.4e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EMR67702.1 - 1.8e-06 28.0 0.2 4.2e-06 26.8 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR67702.1 - 0.01 15.3 0.0 0.051 13.0 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short_C2 PF13561.6 EMR67703.1 - 1.6e-60 204.6 7.9 2.9e-60 203.7 7.9 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR67703.1 - 5e-49 166.4 0.8 7.9e-49 165.8 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR67703.1 - 4.4e-13 49.5 1.8 2.2e-12 47.3 1.8 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR67703.1 - 5.9e-06 25.6 0.3 3.8e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMR67703.1 - 0.002 17.6 1.7 0.0066 15.9 1.7 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR67703.1 - 0.065 12.2 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FMO-like PF00743.19 EMR67704.1 - 3.2e-16 58.9 0.1 7.5e-14 51.0 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMR67704.1 - 2.7e-09 36.6 0.1 6.4e-07 28.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EMR67704.1 - 3.1e-08 33.7 0.0 9.4e-07 29.0 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR67704.1 - 1.8e-06 27.8 0.4 0.0031 17.2 0.1 3.1 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR67704.1 - 2.9e-05 23.5 0.0 0.0034 16.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR67704.1 - 3e-05 24.1 0.4 0.0089 16.0 0.0 4.0 4 2 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 EMR67704.1 - 0.00061 19.1 0.0 0.027 13.7 0.0 3.0 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 EMR67704.1 - 0.002 18.2 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EMR67704.1 - 0.004 16.5 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EMR67704.1 - 0.049 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KxDL PF10241.9 EMR67705.1 - 1.1e-30 105.7 2.4 1.6e-30 105.2 2.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Mating_C PF12737.7 EMR67705.1 - 0.16 11.2 3.3 8.6 5.5 2.1 2.2 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 XylR_N PF06505.11 EMR67705.1 - 0.32 10.7 2.2 0.41 10.4 0.2 2.0 2 0 0 2 2 2 0 Activator of aromatic catabolism DUF883 PF05957.13 EMR67705.1 - 8.4 7.1 8.2 12 6.6 0.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Cir_N PF10197.9 EMR67706.1 - 8.5e-08 32.3 2.8 8.5e-08 32.3 2.8 6.1 4 2 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR adh_short_C2 PF13561.6 EMR67707.1 - 6.9e-62 209.1 2.6 7.7e-62 208.9 2.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR67707.1 - 4.8e-47 160.0 1.5 6.4e-47 159.6 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR67707.1 - 1.7e-09 37.9 1.0 2.5e-09 37.3 1.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMR67707.1 - 0.0025 17.7 0.1 0.004 17.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 EMR67709.1 - 4.1e-56 190.5 0.0 5e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR67709.1 - 7.9e-08 32.9 0.0 1.2e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMR67709.1 - 1.3e-07 31.0 0.0 0.001 18.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EMR67709.1 - 0.00017 21.0 0.1 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR67709.1 - 0.00019 21.1 0.4 0.085 12.4 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 EMR67709.1 - 0.0006 19.0 0.2 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EMR67709.1 - 0.0007 18.8 0.5 0.079 12.0 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMR67709.1 - 0.00088 19.5 0.3 0.0022 18.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR67709.1 - 0.024 13.9 0.1 0.53 9.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR67709.1 - 0.06 13.9 0.3 0.31 11.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR67709.1 - 0.18 10.6 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Borrelia_P83 PF05262.11 EMR67711.1 - 6.5 5.1 20.3 0.14 10.6 9.9 2.2 2 0 0 2 2 2 0 Borrelia P83/100 protein AF-4 PF05110.13 EMR67712.1 - 1.2e-05 23.7 10.3 2.2e-05 22.8 10.3 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Sporozoite_P67 PF05642.11 EMR67712.1 - 8.5e-05 20.9 2.4 7.4 4.5 0.0 3.1 2 1 1 3 3 3 1 Sporozoite P67 surface antigen HAP1_N PF04849.13 EMR67712.1 - 0.00068 18.9 4.2 0.00068 18.9 4.2 2.0 2 0 0 2 2 2 1 HAP1 N-terminal conserved region DUF508 PF04370.12 EMR67712.1 - 1.7 8.4 8.5 4 7.2 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Abhydrolase_6 PF12697.7 EMR67713.1 - 3.4e-12 47.5 0.3 4.8e-12 46.9 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR67713.1 - 0.0038 16.5 0.1 0.0071 15.6 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Acetyltransf_1 PF00583.25 EMR67714.1 - 1.6e-13 50.9 0.1 3.3e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMR67714.1 - 2.4e-06 27.4 0.1 4e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EMR67714.1 - 5.4e-06 26.8 0.0 1.1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR67714.1 - 1.1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR67714.1 - 0.0066 16.5 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RP-C_C PF11800.8 EMR67714.1 - 0.09 12.9 0.2 0.14 12.3 0.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Fructosamin_kin PF03881.14 EMR67715.1 - 4.5e-24 85.1 0.1 5.8e-24 84.8 0.1 1.0 1 0 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 EMR67715.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EMR67715.1 - 0.024 14.6 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_12 PF13424.6 EMR67716.1 - 1.3e-13 51.1 3.7 3.2e-11 43.4 0.1 4.1 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EMR67716.1 - 1.8e-08 34.0 2.4 0.028 14.3 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMR67716.1 - 1.1e-07 31.3 2.8 0.0049 16.7 1.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR67716.1 - 2.3e-07 30.4 5.8 0.0077 16.3 1.1 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 EMR67716.1 - 7e-07 28.7 0.0 7.7e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 EMR67716.1 - 0.00013 21.7 0.0 0.95 9.6 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMR67716.1 - 0.0005 20.1 2.9 0.051 13.8 0.5 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMR67716.1 - 0.0079 16.9 3.6 0.36 11.8 0.1 4.2 3 1 1 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR67716.1 - 0.017 15.4 0.1 0.047 13.9 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EMR67716.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region TPR_6 PF13174.6 EMR67716.1 - 0.054 14.2 1.6 1.3 9.8 0.2 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat IF-2B PF01008.17 EMR67717.1 - 4.2e-33 114.8 0.2 1.2e-32 113.3 0.2 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family LUD_dom PF02589.15 EMR67717.1 - 0.0017 18.1 0.7 0.004 16.9 0.6 1.5 1 1 0 1 1 1 1 LUD domain Alpha_L_fucos PF01120.17 EMR67718.1 - 9.3e-87 291.7 4.4 1.3e-86 291.3 4.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 EMR67718.1 - 0.033 14.3 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 p450 PF00067.22 EMR67719.1 - 1.8e-37 129.2 0.0 4.5e-23 81.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Pyr_redox_2 PF07992.14 EMR67720.1 - 1.7e-44 152.2 0.3 2.7e-44 151.6 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR67720.1 - 6.8e-16 58.6 0.0 1.1e-12 48.3 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR67720.1 - 7.4e-14 51.7 0.0 1.4e-11 44.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR67720.1 - 1.6e-06 28.0 0.1 0.005 16.5 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR67720.1 - 0.00011 21.6 0.3 0.00074 18.8 0.1 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EMR67720.1 - 0.00082 18.6 4.2 0.76 8.8 0.2 4.1 4 1 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EMR67720.1 - 0.00093 18.4 2.9 0.37 9.8 0.2 3.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 EMR67720.1 - 0.0015 19.0 0.1 0.39 11.2 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EMR67720.1 - 0.0054 16.9 0.8 0.25 11.6 0.0 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EMR67720.1 - 0.0064 16.6 0.2 6.6 6.8 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 EMR67720.1 - 0.012 14.8 0.2 0.35 10.0 0.0 2.6 2 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EMR67720.1 - 0.016 14.0 1.0 4.2 6.0 0.2 3.0 2 1 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 EMR67720.1 - 0.029 13.2 0.2 0.32 9.8 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 EMR67720.1 - 0.059 12.7 0.1 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR67720.1 - 0.06 13.3 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pribosyltran PF00156.27 EMR67721.1 - 1.8e-12 47.1 0.0 3.6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain WD40 PF00400.32 EMR67722.1 - 4.4e-43 144.4 28.5 2.7e-11 43.8 1.5 7.2 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR67722.1 - 3.4e-16 59.3 2.0 0.0086 16.4 0.1 5.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR67722.1 - 0.0002 20.1 3.7 0.11 11.1 0.2 3.5 4 0 0 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EMR67722.1 - 0.0027 16.7 0.0 28 3.5 0.0 4.3 3 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PBP1_TM PF14812.6 EMR67723.1 - 0.38 11.2 3.3 0.34 11.3 1.4 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4719 PF15843.5 EMR67723.1 - 3.3 7.8 7.3 0.12 12.5 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) PH_6 PF15406.6 EMR67724.1 - 2e-43 147.2 2.6 2e-43 147.2 2.6 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EMR67724.1 - 7.7e-05 23.1 0.0 0.00022 21.7 0.0 1.8 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 EMR67724.1 - 0.077 13.0 0.2 0.16 12.0 0.0 1.6 2 0 0 2 2 2 0 PH domain PH_13 PF16652.5 EMR67724.1 - 0.083 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain ABC_tran PF00005.27 EMR67726.1 - 2.4e-29 102.6 0.0 4e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMR67726.1 - 1.3e-09 37.8 3.4 8.4e-07 28.6 0.3 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMR67726.1 - 1.6e-05 25.4 1.7 3.6e-05 24.2 1.7 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR67726.1 - 0.00035 20.9 0.8 0.0018 18.5 0.8 2.0 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 EMR67726.1 - 0.0012 19.0 0.1 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_5 PF07728.14 EMR67726.1 - 0.0013 18.7 0.2 0.13 12.2 0.1 3.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EMR67726.1 - 0.0019 17.9 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EMR67726.1 - 0.0083 16.2 1.0 0.026 14.6 1.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EMR67726.1 - 0.014 15.2 0.1 0.048 13.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMR67726.1 - 0.015 15.2 0.5 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.6 EMR67726.1 - 0.016 15.5 0.3 0.082 13.2 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EMR67726.1 - 0.017 14.8 0.1 0.03 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EMR67726.1 - 0.019 14.8 2.6 3.4 7.4 0.7 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EMR67726.1 - 0.029 14.3 0.2 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 EMR67726.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EMR67726.1 - 0.098 12.2 0.0 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 EMR67726.1 - 0.1 12.2 0.1 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 EMR67726.1 - 0.1 12.4 0.3 3.3 7.4 0.0 2.4 3 0 0 3 3 2 0 DEAD/DEAH box helicase Tex_YqgF PF16921.5 EMR67726.1 - 0.11 12.9 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Tex protein YqgF-like domain IIGP PF05049.13 EMR67726.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Aminotran_4 PF01063.19 EMR67727.1 - 2.9e-22 79.6 0.0 4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV OPT PF03169.15 EMR67728.1 - 8.5e-147 490.4 50.0 9.9e-147 490.2 50.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S10 PF00450.22 EMR67729.1 - 2.4e-91 307.2 0.0 3.2e-91 306.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase 2-Hacid_dh_C PF02826.19 EMR67729.1 - 1.9e-37 128.3 0.0 3.9e-37 127.3 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EMR67729.1 - 0.3 11.2 0.8 0.82 9.7 0.7 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans_2 PF11951.8 EMR67730.1 - 6e-12 45.1 0.8 1.2e-11 44.1 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 EMR67731.1 - 1.4e-07 31.5 4.4 1.6e-07 31.3 4.0 1.3 1 1 0 1 1 1 1 ABC transporter transmembrane region GFO_IDH_MocA PF01408.22 EMR67732.1 - 4.6e-21 75.9 0.1 8.8e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EMR67732.1 - 9.9e-06 26.2 0.1 1.9e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sugar_tr PF00083.24 EMR67733.1 - 6.4e-59 200.0 31.1 6.6e-37 127.4 17.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR67733.1 - 4.2e-11 42.4 32.4 3.2e-08 32.9 6.0 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily T_cell_tran_alt PF15128.6 EMR67733.1 - 0.0091 15.8 0.1 0.025 14.4 0.1 1.7 1 0 0 1 1 1 1 T-cell leukemia translocation-altered Peptidase_M48_N PF16491.5 EMR67733.1 - 8.3 6.3 11.0 0.43 10.5 0.7 2.5 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices ADH_zinc_N PF00107.26 EMR67734.1 - 6.3e-08 32.7 0.0 2.1e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR67734.1 - 3.4e-05 23.7 0.1 0.00016 21.5 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain HI0933_like PF03486.14 EMR67734.1 - 0.0009 18.0 0.1 0.0012 17.7 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EMR67734.1 - 0.0015 17.8 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EMR67734.1 - 0.012 14.7 0.7 0.018 14.2 0.7 1.1 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 EMR67734.1 - 0.037 13.5 0.1 0.073 12.5 0.0 1.5 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 EMR67734.1 - 0.08 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FtsK_SpoIIIE PF01580.18 EMR67735.1 - 0.00098 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 EMR67735.1 - 0.033 14.6 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain GFO_IDH_MocA PF01408.22 EMR67736.1 - 1.1e-11 45.6 0.0 1.9e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMR67736.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF3601 PF12208.8 EMR67736.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) F-box-like PF12937.7 EMR67737.1 - 0.0011 18.8 0.1 0.0044 16.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like FTA2 PF13095.6 EMR67738.1 - 1.2e-53 182.0 0.0 1.4e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 adh_short PF00106.25 EMR67739.1 - 3.1e-25 88.8 0.1 4.2e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67739.1 - 1.5e-19 70.5 0.1 1.9e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67739.1 - 1.5e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR67739.1 - 0.14 12.0 0.1 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Glyco_hydro_114 PF03537.13 EMR67740.1 - 6.4e-79 264.5 0.0 7.6e-79 264.3 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ADH_zinc_N PF00107.26 EMR67741.1 - 1.7e-09 37.7 0.0 2.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR67741.1 - 2.5e-06 27.3 0.0 5.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMR67741.1 - 0.12 13.4 0.0 0.23 12.5 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NACHT PF05729.12 EMR67742.1 - 5e-07 29.8 0.2 1.2e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EMR67742.1 - 1.4e-06 28.8 0.1 6.6e-06 26.6 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMR67742.1 - 2.2e-05 24.7 0.0 5.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EMR67742.1 - 5.5e-05 22.5 0.0 0.00013 21.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 EMR67742.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 EMR67742.1 - 0.0036 16.6 0.1 0.1 11.8 0.1 2.4 1 1 1 2 2 2 1 KAP family P-loop domain TsaE PF02367.17 EMR67742.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE But2 PF09792.9 EMR67743.1 - 1.1e-53 181.4 0.4 1.1e-53 181.4 0.4 3.4 2 1 1 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 EMR67744.1 - 3.5e-09 37.4 0.0 6.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 EMR67745.1 - 1.1e-17 64.0 0.0 1.2e-16 60.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 KR PF08659.10 EMR67746.1 - 5.8e-21 75.2 1.6 5.2e-19 68.9 0.6 2.5 1 1 1 2 2 2 2 KR domain ketoacyl-synt PF00109.26 EMR67746.1 - 9.8e-21 74.5 1.3 9.8e-10 38.4 0.0 3.4 1 1 2 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N PF00107.26 EMR67746.1 - 7.7e-09 35.6 0.0 2e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ketoacyl-synt_C PF02801.22 EMR67746.1 - 2.5e-05 24.3 0.1 6.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EMR67746.1 - 3.7e-05 24.0 0.0 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ig_GlcNase PF18368.1 EMR67749.1 - 2.1e-34 117.8 0.2 2.3e-33 114.5 0.0 2.6 3 0 0 3 3 3 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 EMR67749.1 - 6.5e-11 42.9 0.1 3.3e-10 40.6 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 EMR67749.1 - 1.6e-07 31.8 0.4 1.4e-06 28.8 0.1 2.5 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain DUF2528 PF10800.8 EMR67749.1 - 0.015 15.9 0.0 0.046 14.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) Ig_mannosidase PF17753.1 EMR67749.1 - 0.021 14.5 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 Ig-fold domain Glyco_hydro_2_C PF02836.17 EMR67749.1 - 0.031 13.4 0.1 0.052 12.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF2735 PF10931.8 EMR67749.1 - 1.3 9.7 3.4 16 6.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2735) Fungal_trans PF04082.18 EMR67751.1 - 1.9e-09 37.0 0.0 2.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.33 EMR67752.1 - 1e-05 25.2 0.7 9.1e-05 22.2 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EMR67752.1 - 0.011 15.7 0.6 0.027 14.4 0.1 1.9 2 0 0 2 2 2 0 F-box-like Pam17 PF08566.10 EMR67753.1 - 2.9e-61 206.1 0.0 4.2e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Pex14_N PF04695.13 EMR67753.1 - 0.15 12.7 7.5 0.35 11.5 7.5 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Transp_cyt_pur PF02133.15 EMR67754.1 - 5.8e-56 190.1 15.1 7.6e-56 189.7 15.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PRRSV_2b PF07069.11 EMR67754.1 - 0.15 12.6 1.1 0.8 10.3 0.0 2.5 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b ThiF PF00899.21 EMR67755.1 - 7.5e-54 182.7 0.0 1.1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EMR67755.1 - 1.5e-12 47.9 0.0 7.2e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EMR67755.1 - 0.0071 16.4 0.4 0.026 14.6 0.0 2.1 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase MscS_porin PF12795.7 EMR67755.1 - 0.014 15.0 1.5 0.021 14.4 1.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Wtap PF17098.5 EMR67755.1 - 0.043 13.7 0.3 0.12 12.3 0.2 1.7 2 0 0 2 2 2 0 WTAP/Mum2p family Spc29 PF17082.5 EMR67755.1 - 0.13 12.1 0.9 0.21 11.4 0.9 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 SlyX PF04102.12 EMR67755.1 - 0.63 10.7 4.3 0.33 11.6 1.1 2.2 2 0 0 2 2 2 0 SlyX FAD_binding_3 PF01494.19 EMR67755.1 - 0.83 8.8 3.1 1.3 8.2 3.1 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EMR67755.1 - 0.99 8.4 2.4 1.4 7.9 2.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NICE-1 PF15845.5 EMR67756.1 - 2.7 8.8 6.2 14 6.6 1.5 2.3 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family SLX9 PF15341.6 EMR67757.1 - 4.9e-37 127.2 6.6 6.6e-37 126.8 6.6 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Syntaxin-6_N PF09177.11 EMR67757.1 - 0.017 15.7 2.7 0.11 13.1 0.4 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal adh_short PF00106.25 EMR67760.1 - 5.1e-12 45.7 2.5 8.1e-10 38.5 1.5 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR67760.1 - 9.1e-06 25.7 0.3 6.2e-05 23.0 0.3 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMR67760.1 - 2.3e-05 24.0 2.1 0.048 13.2 0.4 2.5 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase H_PPase PF03030.16 EMR67760.1 - 0.029 13.0 0.6 0.055 12.1 0.1 1.6 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase p450 PF00067.22 EMR67761.1 - 1.8e-38 132.5 0.0 2.7e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 BtrH_N PF14399.6 EMR67761.1 - 0.13 12.5 0.1 0.96 9.7 0.0 2.1 2 0 0 2 2 2 0 Butirosin biosynthesis protein H, N-terminal FAD_binding_3 PF01494.19 EMR67762.1 - 5.6e-08 32.4 0.1 1.6e-07 31.0 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR67762.1 - 2.7e-06 26.8 0.5 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR67762.1 - 0.00019 20.9 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR67762.1 - 0.00038 20.6 1.8 0.0009 19.4 1.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR67762.1 - 0.0074 15.4 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR67762.1 - 0.019 14.5 6.0 0.028 14.0 5.4 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EMR67762.1 - 0.075 12.3 0.4 0.13 11.5 0.1 1.4 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 EMR67762.1 - 0.18 11.7 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EMR67762.1 - 0.43 9.8 2.1 13 4.9 1.5 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR67762.1 - 0.92 9.5 2.3 7.1 6.6 1.2 2.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding PhoLip_ATPase_C PF16212.5 EMR67763.1 - 1.3e-71 241.3 20.2 1.3e-71 241.3 20.2 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMR67763.1 - 5.7e-24 83.6 1.2 2.3e-23 81.6 0.1 2.5 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EMR67763.1 - 2.2e-12 46.9 0.0 4.5e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EMR67763.1 - 2.6e-12 46.6 0.0 9.2e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMR67763.1 - 2.9e-12 47.3 0.1 4.6e-05 23.8 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMR67763.1 - 0.00047 20.0 0.0 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tannase PF07519.11 EMR67764.1 - 7.8e-58 196.5 1.4 4.6e-54 184.1 0.1 2.3 1 1 1 2 2 2 2 Tannase and feruloyl esterase GMC_oxred_N PF00732.19 EMR67765.1 - 3.4e-61 207.2 0.0 5.8e-39 134.2 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR67765.1 - 5.9e-37 127.4 0.0 1e-36 126.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMR67765.1 - 9.9e-05 21.5 0.1 0.00014 21.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EMR67765.1 - 0.0067 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR67765.1 - 0.015 14.6 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 EMR67765.1 - 0.066 12.8 1.0 0.21 11.2 1.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR67765.1 - 0.14 11.2 0.1 0.86 8.6 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pkinase PF00069.25 EMR67766.1 - 9.1e-18 64.6 0.0 1.7e-15 57.1 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR67766.1 - 1.1e-05 24.9 0.0 0.00076 18.8 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Nop10p PF04135.12 EMR67767.1 - 3.5e-20 71.8 0.2 4.2e-20 71.5 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family 4HBT_3 PF13622.6 EMR67768.1 - 2.6e-46 158.9 11.6 2.2e-45 155.9 11.6 1.9 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMR67768.1 - 5.3e-05 23.1 0.0 0.00019 21.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA thioesterase Glyco_transf_25 PF01755.17 EMR67769.1 - 5e-06 26.5 0.0 9.9e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) adh_short PF00106.25 EMR67770.1 - 8.7e-45 152.6 0.3 1.1e-44 152.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67770.1 - 1.4e-31 109.9 0.0 1.7e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67770.1 - 6.5e-07 29.4 0.1 9.2e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMR67770.1 - 0.0015 17.9 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMR67770.1 - 0.0023 17.4 0.1 0.0038 16.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EMR67770.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 EMR67770.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 EMR67771.1 - 3.2e-10 39.8 4.0 3.4e-06 26.6 0.2 2.5 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMR67771.1 - 8e-05 22.8 0.8 0.00089 19.4 0.1 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR67771.1 - 0.00016 21.0 2.2 0.00044 19.6 2.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR67771.1 - 0.0042 16.3 0.3 0.0072 15.6 0.3 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EMR67771.1 - 0.062 13.3 1.1 2.6 8.0 0.2 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMR67771.1 - 0.081 12.2 0.4 0.13 11.5 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR67771.1 - 0.088 11.6 6.1 2.6 6.8 1.7 2.9 2 1 1 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 EMR67771.1 - 0.14 10.8 0.4 0.23 10.1 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 EMR67771.1 - 0.66 9.5 6.7 0.72 9.4 1.3 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase RVT_1 PF00078.27 EMR67772.1 - 2e-06 27.5 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MerR-DNA-bind PF09278.11 EMR67772.1 - 0.034 14.7 3.8 0.09 13.3 1.4 3.0 3 0 0 3 3 3 0 MerR, DNA binding Lyase_aromatic PF00221.19 EMR67773.1 - 4e-136 454.4 8.9 5.7e-136 453.9 8.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase MSA-2c PF12238.8 EMR67774.1 - 0.24 11.4 3.5 0.41 10.6 3.5 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c NOB1_Zn_bind PF08772.11 EMR67775.1 - 8.1e-31 106.0 1.0 1.3e-30 105.3 1.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EMR67775.1 - 8.8e-30 103.1 0.0 2.5e-29 101.6 0.0 1.8 1 0 0 1 1 1 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 EMR67775.1 - 0.0079 15.8 6.9 0.0088 15.7 1.2 2.5 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain WRNPLPNID PF15017.6 EMR67775.1 - 0.0093 16.8 8.3 0.0093 16.8 8.3 2.5 3 0 0 3 3 3 1 Putative WW-binding domain and destruction box HypA PF01155.19 EMR67775.1 - 0.017 15.2 0.0 0.33 11.0 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EMR67775.1 - 1 9.5 4.2 0.84 9.8 2.0 1.9 2 0 0 2 2 2 0 Zinc ribbon domain ADH_N PF08240.12 EMR67776.1 - 1.2e-24 86.3 0.2 1.8e-24 85.7 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR67776.1 - 1.5e-14 54.1 0.0 2.1e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR67776.1 - 1.4e-08 34.5 0.2 9.1e-08 31.8 0.1 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMR67776.1 - 0.0011 20.1 0.0 0.002 19.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 EMR67776.1 - 0.022 14.0 0.1 0.11 11.7 0.1 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase OTT_1508_deam PF14441.6 EMR67776.1 - 0.023 14.7 0.3 0.046 13.7 0.3 1.5 1 0 0 1 1 1 0 OTT_1508-like deaminase TrkA_N PF02254.18 EMR67776.1 - 0.063 13.5 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.24 EMR67778.1 - 2.6e-61 207.9 34.0 1.1e-40 139.9 21.7 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR67778.1 - 3.7e-15 55.7 35.9 2.4e-10 39.9 3.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.12 EMR67778.1 - 0.088 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF697) UL42 PF17638.2 EMR67778.1 - 0.51 10.3 2.3 0.39 10.7 0.3 1.9 2 0 0 2 2 2 0 HCMV UL42 ADH_N PF08240.12 EMR67779.1 - 1e-25 89.7 5.5 2e-25 88.8 5.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR67779.1 - 1e-15 57.8 0.1 5.3e-15 55.5 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMR67779.1 - 7.9e-05 22.1 0.3 0.00014 21.3 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Apolipoprotein PF01442.18 EMR67780.1 - 0.00014 21.8 0.4 0.00023 21.1 0.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain FMO-like PF00743.19 EMR67782.1 - 2.7e-27 95.4 0.0 9.3e-25 87.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR67782.1 - 4e-24 85.4 0.0 1.2e-22 80.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR67782.1 - 8.4e-20 71.2 0.0 1.3e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR67782.1 - 2.6e-15 56.4 0.0 2.2e-11 43.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EMR67782.1 - 4.4e-07 29.5 0.4 0.0028 16.9 0.3 3.1 2 1 1 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EMR67782.1 - 9.7e-07 28.3 0.1 0.026 13.9 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EMR67782.1 - 7.8e-06 26.4 0.2 0.029 14.9 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR67782.1 - 1.2e-05 25.4 0.0 0.00022 21.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMR67782.1 - 1.3e-05 25.3 1.1 0.56 10.2 0.0 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EMR67782.1 - 5.1e-05 22.5 0.0 0.041 12.9 0.0 3.4 4 0 0 4 4 4 1 Lycopene cyclase protein HI0933_like PF03486.14 EMR67782.1 - 7.3e-05 21.6 0.7 0.038 12.7 0.0 3.6 4 0 0 4 4 4 1 HI0933-like protein GIDA PF01134.22 EMR67782.1 - 9.1e-05 21.7 0.0 1.9 7.5 0.0 3.9 4 0 0 4 4 4 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 EMR67782.1 - 0.00011 22.3 0.1 0.077 13.0 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EMR67782.1 - 0.00012 22.4 0.8 0.26 11.6 0.0 3.4 4 0 0 4 4 3 1 TrkA-N domain NAD_binding_7 PF13241.6 EMR67782.1 - 0.00041 20.8 0.0 0.03 14.8 0.0 2.6 3 0 0 3 3 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EMR67782.1 - 0.0005 20.0 0.2 0.15 11.9 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EMR67782.1 - 0.0014 17.8 0.1 0.1 11.7 0.1 2.9 3 0 0 3 3 3 1 FAD binding domain ApbA PF02558.16 EMR67782.1 - 0.0024 17.6 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EMR67782.1 - 0.0036 16.6 0.0 1.5 8.0 0.0 3.5 4 0 0 4 4 4 1 Thi4 family IlvN PF07991.12 EMR67782.1 - 0.0042 16.7 0.2 0.039 13.5 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain SnoaL_2 PF12680.7 EMR67782.1 - 0.0084 16.7 0.0 0.036 14.7 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain F420_oxidored PF03807.17 EMR67782.1 - 0.0094 16.5 0.1 6.8 7.3 0.0 3.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 EMR67782.1 - 0.014 15.0 0.1 3.5 7.1 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMR67782.1 - 0.065 12.5 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMR67782.1 - 0.19 11.3 0.0 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NTF2 PF02136.20 EMR67782.1 - 0.2 12.2 0.0 0.41 11.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain ELFV_dehydrog PF00208.21 EMR67782.1 - 0.21 11.3 0.2 0.43 10.3 0.2 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Fungal_trans PF04082.18 EMR67783.1 - 7.6e-22 77.6 0.0 1.1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR67783.1 - 6.3e-07 29.4 12.4 9.9e-07 28.8 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2776 PF10951.8 EMR67783.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) WD40 PF00400.32 EMR67784.1 - 3.8e-17 62.3 8.7 0.00025 21.8 0.3 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR67784.1 - 4.3e-09 36.6 0.1 0.01 16.1 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR67784.1 - 0.006 15.3 0.4 1.9 7.0 0.0 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EMR67784.1 - 0.031 13.2 0.4 0.55 9.1 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein G-alpha PF00503.20 EMR67785.1 - 8.2e-125 416.6 2.9 9.4e-125 416.4 2.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EMR67785.1 - 3.1e-15 56.1 1.7 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EMR67785.1 - 8.3e-05 22.3 0.0 0.00036 20.3 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EMR67785.1 - 0.0022 17.4 3.2 0.11 11.9 0.0 2.7 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EMR67785.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EMR67785.1 - 0.024 14.8 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 EMR67785.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 EMR67785.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 EMR67785.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EMR67785.1 - 0.13 12.3 0.1 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase D123 PF07065.14 EMR67786.1 - 2.5e-117 391.4 0.0 2.9e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 D123 Gly-rich_Ago1 PF12764.7 EMR67786.1 - 0.37 11.6 0.2 0.37 11.6 0.2 2.4 3 0 0 3 3 3 0 Glycine-rich region of argonaut BLOC1S3 PF15753.5 EMR67786.1 - 0.53 10.4 5.8 0.18 11.9 1.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 YL1 PF05764.13 EMR67786.1 - 0.65 10.1 7.8 0.11 12.6 0.8 2.2 2 0 0 2 2 2 0 YL1 nuclear protein DUF3716 PF12511.8 EMR67787.1 - 1e-16 60.7 8.3 1.7e-16 60.0 8.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Med3 PF11593.8 EMR67787.1 - 0.0028 16.9 9.5 0.0044 16.3 9.5 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF5544 PF17698.1 EMR67787.1 - 0.025 14.7 0.2 0.025 14.7 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5544) FAM70 PF14967.6 EMR67787.1 - 7.1 6.0 7.2 2.8 7.3 4.6 1.6 2 0 0 2 2 2 0 FAM70 protein Nnf1 PF03980.14 EMR67788.1 - 1.6e-16 60.7 0.1 1.6e-16 60.7 0.1 2.3 2 1 0 2 2 2 1 Nnf1 Spt20 PF12090.8 EMR67788.1 - 0.043 13.4 9.7 0.046 13.3 9.7 1.1 1 0 0 1 1 1 0 Spt20 family SOG2 PF10428.9 EMR67788.1 - 0.12 11.5 12.9 0.15 11.3 12.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 EMR67788.1 - 0.15 12.0 10.3 0.15 12.0 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TP2 PF01254.18 EMR67788.1 - 0.33 11.6 14.5 0.49 11.0 14.5 1.2 1 0 0 1 1 1 0 Nuclear transition protein 2 Pex14_N PF04695.13 EMR67788.1 - 0.41 11.3 15.2 0.67 10.6 15.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Podoplanin PF05808.11 EMR67788.1 - 1.5 8.9 10.1 2.1 8.4 10.1 1.2 1 0 0 1 1 1 0 Podoplanin Presenilin PF01080.17 EMR67788.1 - 2.9 6.5 6.7 3.2 6.4 6.7 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EMR67788.1 - 3.5 6.2 8.5 3.9 6.1 8.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAP1 PF07218.11 EMR67788.1 - 5.6 5.1 7.8 6.9 4.8 7.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) cwf21 PF08312.12 EMR67790.1 - 6.9e-18 64.5 8.5 6.9e-18 64.5 8.5 2.1 2 0 0 2 2 2 1 cwf21 domain GvpG PF05120.12 EMR67790.1 - 0.58 10.2 6.2 3.1 7.9 0.5 2.5 2 1 0 2 2 2 0 Gas vesicle protein G DUF1640 PF07798.11 EMR67791.1 - 1.4e-32 113.2 10.4 2.4e-32 112.4 10.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 EMR67791.1 - 0.0027 17.6 6.5 0.0046 16.9 6.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PgaD PF13994.6 EMR67791.1 - 0.035 14.2 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 PgaD-like protein Type2_restr_D3 PF16902.5 EMR67791.1 - 0.068 13.1 0.3 0.19 11.7 0.3 1.9 1 1 0 1 1 1 0 Type-2 restriction enzyme D3 domain ALMT PF11744.8 EMR67791.1 - 0.24 10.2 2.3 0.33 9.7 2.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5082 PF16888.5 EMR67791.1 - 0.32 11.3 8.6 0.23 11.7 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Fzo_mitofusin PF04799.13 EMR67791.1 - 0.75 9.3 8.1 0.92 9.0 5.3 2.2 1 1 2 3 3 3 0 fzo-like conserved region adh_short PF00106.25 EMR67792.1 - 2.2e-28 99.1 0.0 2.9e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67792.1 - 1e-19 71.1 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67792.1 - 5.6e-10 39.4 0.0 1e-09 38.6 0.0 1.4 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EMR67792.1 - 0.0018 18.8 0.0 0.024 15.2 0.1 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMR67792.1 - 0.0033 17.5 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 EMR67792.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_binding_2 PF13380.6 EMR67792.1 - 0.028 14.9 0.2 0.096 13.2 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain NAD_binding_7 PF13241.6 EMR67792.1 - 0.039 14.4 0.0 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Epimerase PF01370.21 EMR67792.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 EMR67792.1 - 0.15 12.0 0.2 1 9.3 0.0 2.3 2 1 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Sas10 PF09368.10 EMR67793.1 - 4.2e-24 84.8 9.7 4.2e-24 84.8 9.7 3.0 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EMR67793.1 - 3.7e-11 43.5 0.1 3.7e-11 43.5 0.1 2.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Plk4_PB1 PF18190.1 EMR67793.1 - 0.058 13.6 0.2 0.16 12.2 0.2 1.7 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 DUF1771 PF08590.10 EMR67794.1 - 1.5e-23 82.9 9.2 1.5e-23 82.9 9.2 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.21 EMR67794.1 - 2.1e-11 44.0 0.2 2.1e-11 44.0 0.2 2.4 2 1 0 3 3 3 1 Smr domain Mlh1_C PF16413.5 EMR67794.1 - 0.053 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus HET PF06985.11 EMR67795.1 - 0.0032 17.8 4.1 0.018 15.4 0.2 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 EMR67796.1 - 1.2e-30 106.6 28.3 1.2e-30 106.6 28.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 EMR67796.1 - 0.64 9.8 0.0 0.64 9.8 0.0 2.9 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like APH PF01636.23 EMR67798.1 - 1.8e-20 73.9 0.0 2.3e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMR67798.1 - 1.4e-05 24.8 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF728 PF05304.12 EMR67798.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF728) DUF1679 PF07914.11 EMR67798.1 - 0.18 10.6 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) VanZ PF04892.12 EMR67799.1 - 0.0012 19.5 0.9 0.0018 18.9 0.9 1.2 1 0 0 1 1 1 1 VanZ like family Nop14 PF04147.12 EMR67799.1 - 0.0041 15.4 15.2 0.0051 15.1 15.2 1.0 1 0 0 1 1 1 1 Nop14-like family Phage_holin_2_4 PF16082.5 EMR67799.1 - 0.059 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Paf1 PF03985.13 EMR67799.1 - 0.059 12.4 5.9 0.064 12.3 5.9 1.1 1 0 0 1 1 1 0 Paf1 Cwf_Cwc_15 PF04889.12 EMR67799.1 - 0.076 12.7 13.0 0.088 12.5 13.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EMR67799.1 - 0.11 10.6 17.6 0.14 10.3 17.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 EMR67799.1 - 0.25 11.5 16.1 0.33 11.2 16.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 EMR67799.1 - 0.47 8.7 12.7 0.69 8.1 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EMR67799.1 - 0.54 9.5 13.8 0.67 9.2 13.8 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 EMR67799.1 - 0.55 9.0 4.0 0.62 8.8 4.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RXT2_N PF08595.11 EMR67799.1 - 1.1 9.2 9.6 1.8 8.6 9.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EMR67799.1 - 1.4 8.2 16.1 1.9 7.8 16.1 1.2 1 0 0 1 1 1 0 NOA36 protein SURF2 PF05477.11 EMR67799.1 - 1.7 8.3 4.9 2.3 7.8 4.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Sigma70_ner PF04546.13 EMR67799.1 - 1.7 8.4 11.9 2.4 8.0 11.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.13 EMR67799.1 - 2.3 8.3 20.0 3.5 7.7 20.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 EMR67799.1 - 2.3 7.5 16.6 2.6 7.4 16.6 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EMR67799.1 - 2.6 7.1 21.7 3.5 6.7 21.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) eIF-3c_N PF05470.12 EMR67799.1 - 6.5 4.9 9.0 8.2 4.6 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sporozoite_P67 PF05642.11 EMR67799.1 - 7.4 4.5 10.5 9.7 4.1 10.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HIP1_clath_bdg PF16515.5 EMR67800.1 - 0.59 10.8 46.3 0.5 11.0 10.7 6.1 3 3 3 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EMR67800.1 - 0.89 9.6 0.0 0.89 9.6 0.0 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 EMR67800.1 - 1.5 8.7 10.5 0.43 10.5 0.2 3.3 3 1 1 4 4 4 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 EMR67800.1 - 4.5 7.3 32.3 1.7 8.7 5.2 4.2 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF4470 PF14737.6 EMR67801.1 - 1.9e-14 53.6 0.0 4.9e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 EMR67801.1 - 0.011 15.8 0.1 0.29 11.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMR67801.1 - 0.052 13.8 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat XPG_I PF00867.18 EMR67802.1 - 1.7e-31 108.4 0.0 1.7e-31 108.4 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EMR67802.1 - 1.6e-29 102.4 0.0 1.6e-29 102.4 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EMR67802.1 - 6.1e-06 26.8 0.7 7.7e-05 23.2 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF262 PF03235.14 EMR67802.1 - 0.21 11.7 4.8 0.43 10.7 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF262 AAA_23 PF13476.6 EMR67802.1 - 0.55 10.7 8.5 0.51 10.8 6.0 2.0 2 0 0 2 2 2 0 AAA domain SRR1 PF07985.12 EMR67803.1 - 3.9e-05 23.6 0.0 0.00011 22.2 0.0 1.8 2 0 0 2 2 2 1 SRR1 NYN_YacP PF05991.11 EMR67804.1 - 1.7e-05 24.8 0.1 6.5e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 YacP-like NYN domain PIN_9 PF18477.1 EMR67804.1 - 0.008 16.5 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Mut7-C PF01927.16 EMR67804.1 - 0.22 11.6 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain adh_short_C2 PF13561.6 EMR67805.1 - 5.5e-62 209.4 0.6 6.3e-62 209.2 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR67805.1 - 4.1e-41 140.6 1.0 4.8e-41 140.4 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR67805.1 - 4.4e-13 49.5 0.6 6.4e-13 49.0 0.6 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EMR67805.1 - 0.12 12.3 1.7 0.34 10.9 0.2 2.3 1 1 2 3 3 3 0 Zinc-binding dehydrogenase Acetyltransf_2 PF00797.17 EMR67806.1 - 2.7e-11 43.7 0.1 1.3e-10 41.4 0.1 1.9 1 1 0 1 1 1 1 N-acetyltransferase Clr5 PF14420.6 EMR67807.1 - 1.8e-12 47.3 0.2 3.7e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 Clr5 domain BH3 PF15285.6 EMR67808.1 - 0.019 14.8 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Acyl-CoA_dh_1 PF00441.24 EMR67809.1 - 1.5e-41 142.0 0.5 2.2e-41 141.5 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMR67809.1 - 2.7e-21 75.6 0.1 4.8e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMR67809.1 - 2.7e-19 69.9 0.0 5.7e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 EMR67809.1 - 3.2e-19 68.9 0.7 5.9e-19 68.0 0.7 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 EMR67809.1 - 2.5e-09 37.5 0.0 4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acetyltransf_1 PF00583.25 EMR67810.1 - 5.6e-08 33.0 0.0 8.4e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR67810.1 - 1.6e-06 28.1 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR67810.1 - 2.3e-05 24.7 0.0 4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR67810.1 - 8.7e-05 22.4 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMR67810.1 - 0.00057 20.0 0.0 0.033 14.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR67810.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EMR67810.1 - 0.028 15.1 0.5 0.12 13.1 0.5 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.7 EMR67811.1 - 4.1e-11 43.9 14.5 1.4e-10 42.2 14.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR67811.1 - 1.6e-08 34.5 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR67811.1 - 0.00031 20.1 0.4 0.016 14.5 0.1 2.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EMR67811.1 - 0.11 12.2 0.0 0.73 9.5 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.7 EMR67811.1 - 0.18 10.6 0.0 0.47 9.3 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme adh_short PF00106.25 EMR67812.1 - 4.6e-31 107.8 0.0 5.7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67812.1 - 2.2e-15 56.9 0.0 2.8e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67812.1 - 9.4e-05 22.4 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EMR67812.1 - 0.0049 16.9 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EMR67812.1 - 0.0093 16.2 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EMR67812.1 - 0.013 15.0 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR67812.1 - 0.029 14.3 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 EMR67812.1 - 0.031 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EMR67812.1 - 0.081 13.1 0.0 0.25 11.5 0.0 1.8 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase HA PF03457.14 EMR67812.1 - 0.15 12.4 0.0 19 5.7 0.0 2.3 2 0 0 2 2 2 0 Helicase associated domain DUF1776 PF08643.10 EMR67812.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Thioesterase PF00975.20 EMR67814.1 - 2.2e-14 54.1 0.0 2.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EMR67814.1 - 7.9e-05 23.4 0.2 9.7e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family TatC PF00902.18 EMR67815.1 - 0.2 11.4 11.9 0.26 11.1 11.9 1.1 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF4181 PF13789.6 EMR67815.1 - 0.98 9.7 10.0 2 8.7 10.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) Glyco_hydro_43 PF04616.14 EMR67816.1 - 3.5e-24 85.6 0.0 6.2e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_11 PF00457.17 EMR67817.1 - 8.3e-72 240.5 13.0 9.9e-72 240.3 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 ubiquitin PF00240.23 EMR67818.1 - 0.00034 20.3 0.4 0.0032 17.2 0.2 2.3 1 1 1 2 2 2 1 Ubiquitin family NACHT PF05729.12 EMR67820.1 - 0.02 14.8 0.3 0.042 13.8 0.3 1.5 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_61 PF03443.14 EMR67821.1 - 4e-51 173.9 0.0 4.6e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HAD_2 PF13419.6 EMR67822.1 - 3e-22 79.6 0.0 4.2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR67822.1 - 1.5e-10 41.8 0.0 2.7e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR67822.1 - 7.5e-07 29.1 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Vitelline_membr PF10542.9 EMR67822.1 - 0.15 11.9 0.0 0.61 10.0 0.0 2.0 1 1 1 2 2 2 0 Vitelline membrane cysteine-rich region Methyltransf_23 PF13489.6 EMR67823.1 - 5.4e-11 42.6 0.0 5.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR67823.1 - 2.8e-07 31.1 0.0 4.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR67823.1 - 1.8e-06 28.6 0.0 3.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR67823.1 - 4.5e-05 24.1 0.0 7.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR67823.1 - 0.0009 18.6 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EMR67823.1 - 0.0048 16.7 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pyridoxal_deC PF00282.19 EMR67824.1 - 1.6e-71 241.1 0.0 2e-61 207.8 0.0 2.3 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EMR67824.1 - 4.3e-06 25.9 0.0 6.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMR67824.1 - 0.00019 20.8 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DNA_pol_phi PF04931.13 EMR67824.1 - 1.4 6.9 2.9 1.9 6.5 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi COPI_C PF06957.11 EMR67824.1 - 7.1 5.3 5.1 11 4.6 5.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ABC_membrane PF00664.23 EMR67825.1 - 4.9e-42 144.5 12.4 6.6e-42 144.1 12.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMR67825.1 - 4.7e-34 117.8 0.0 1.4e-32 113.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EMR67825.1 - 3.5e-05 23.4 0.0 0.016 14.7 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMR67825.1 - 0.00034 21.1 0.0 0.00088 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMR67825.1 - 0.00036 20.5 0.0 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EMR67825.1 - 0.00059 19.7 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EMR67825.1 - 0.0016 18.5 0.0 0.019 15.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EMR67825.1 - 0.005 17.1 0.2 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMR67825.1 - 0.0061 16.8 1.3 0.012 15.9 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 EMR67825.1 - 0.007 16.4 0.0 0.039 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EMR67825.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMR67825.1 - 0.018 14.8 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EMR67825.1 - 0.032 14.8 2.8 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMR67825.1 - 0.044 13.3 0.2 0.11 12.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EMR67825.1 - 0.046 14.1 0.0 0.27 11.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMR67825.1 - 0.055 14.0 0.0 0.26 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EMR67825.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_10 PF12846.7 EMR67825.1 - 0.074 12.0 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain ATP-synt_ab PF00006.25 EMR67825.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EMR67825.1 - 0.1 12.5 0.2 0.57 10.1 0.0 2.2 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 EMR67825.1 - 0.1 12.7 0.0 0.1 12.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain Bromodomain PF00439.25 EMR67826.1 - 3.3e-18 65.5 0.4 3.3e-18 65.5 0.4 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 EMR67826.1 - 1.5e-09 37.7 0.0 3.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 EMR67826.1 - 0.093 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Histone-fold protein 3Beta_HSD PF01073.19 EMR67828.1 - 2.2e-13 49.9 0.0 1.2e-12 47.4 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMR67828.1 - 1.5e-11 44.2 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMR67828.1 - 1.6e-06 27.5 0.0 0.00077 18.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EMR67828.1 - 2.4e-06 27.6 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR67828.1 - 1.8e-05 24.4 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EMR67828.1 - 5.5e-05 23.2 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR67828.1 - 0.0012 18.1 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMR67828.1 - 0.029 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_16 PF00722.21 EMR67829.1 - 5.6e-12 45.5 0.1 8.3e-12 44.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EMR67829.1 - 0.00015 20.3 3.1 0.035 12.5 0.5 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Abhydrolase_6 PF12697.7 EMR67830.1 - 9.3e-08 32.9 1.7 1e-07 32.8 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR67830.1 - 0.00019 20.8 0.1 0.00049 19.4 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EMR67830.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme AKAP2_C PF15304.6 EMR67831.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus DUF2408 PF10303.9 EMR67832.1 - 3e-32 112.0 10.4 6.1e-15 56.0 3.4 5.3 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 EMR67832.1 - 0.00078 19.8 6.1 0.014 15.8 0.1 4.0 5 0 0 5 5 5 2 Snapin/Pallidin YCII PF03795.14 EMR67833.1 - 1.5e-10 41.3 0.0 1.8e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain G-patch PF01585.23 EMR67834.1 - 6e-13 48.5 0.5 1.4e-12 47.3 0.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EMR67834.1 - 0.0011 18.7 0.0 0.0037 17.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRCC PF10253.9 EMR67834.1 - 0.25 12.1 19.7 0.079 13.7 2.6 2.7 2 1 1 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Recep_L_domain PF01030.24 EMR67835.1 - 4.8e-12 46.0 0.6 0.02 15.0 0.0 3.6 2 1 1 3 3 3 3 Receptor L domain Ecm33 PF12454.8 EMR67835.1 - 1.8 8.8 7.5 0.18 12.0 2.1 2.1 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein UBX PF00789.20 EMR67836.1 - 4.1e-05 23.7 0.0 8.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain Selenoprotein_S PF06936.11 EMR67836.1 - 0.012 15.5 13.6 0.017 15.0 13.6 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF4551 PF15087.6 EMR67836.1 - 0.47 9.2 9.4 0.53 9.0 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V_ATPase_I PF01496.19 EMR67836.1 - 1.6 6.5 3.1 1.5 6.6 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MDM1 PF15501.6 EMR67836.1 - 2 7.4 19.9 2.3 7.3 19.9 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 CDC45 PF02724.14 EMR67836.1 - 2.1 6.6 10.6 2.1 6.6 10.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 EMR67836.1 - 4.2 6.6 11.8 5.9 6.1 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L18_c PF14204.6 EMR67837.1 - 3.2e-37 127.3 6.6 3.8e-37 127.1 6.6 1.1 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 EMR67837.1 - 0.13 12.5 0.6 2.9 8.2 0.0 2.7 2 1 0 3 3 3 0 Threonine synthase N terminus FAM176 PF14851.6 EMR67838.1 - 1 9.0 5.4 0.16 11.6 0.5 1.9 1 1 1 2 2 2 0 FAM176 family TLP-20 PF06088.11 EMR67838.1 - 3.4 7.5 5.3 0.83 9.5 1.8 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) AMP-binding PF00501.28 EMR67839.1 - 9.6e-77 258.3 0.0 4.9e-52 177.0 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EMR67839.1 - 1.5e-19 70.7 0.3 4.2e-19 69.3 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_60s PF00428.19 EMR67840.1 - 4.3e-26 91.3 9.5 5.2e-26 91.0 9.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein AP_endonuc_2 PF01261.24 EMR67841.1 - 2.7e-37 128.2 0.0 3.9e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Aldedh PF00171.22 EMR67842.1 - 3.3e-98 329.2 0.0 3.8e-98 329.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HicB_lk_antitox PF15919.5 EMR67842.1 - 0.14 12.3 0.0 13 5.9 0.1 2.4 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Phage_holin_3_6 PF07332.11 EMR67843.1 - 0.052 13.6 0.1 0.052 13.6 0.1 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SIT PF15330.6 EMR67843.1 - 0.13 12.7 0.1 0.86 10.1 0.1 2.2 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DnaJ PF00226.31 EMR67846.1 - 1.2e-13 50.9 0.1 4e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain RNA_pol_3_Rpc31 PF11705.8 EMR67846.1 - 0.00071 19.9 13.0 0.00071 19.9 13.0 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 EMR67846.1 - 0.0014 18.1 8.0 0.0014 18.1 8.0 2.1 1 1 1 2 2 2 1 BUD22 DUF719 PF05334.13 EMR67846.1 - 0.21 11.8 7.5 0.23 11.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) TFIIA PF03153.13 EMR67846.1 - 0.67 9.9 24.7 1 9.3 24.7 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Opi1 PF08618.10 EMR67846.1 - 1.8 7.7 6.6 11 5.2 6.5 2.0 1 1 0 1 1 1 0 Transcription factor Opi1 Pex14_N PF04695.13 EMR67846.1 - 2.1 9.0 7.9 0.088 13.5 1.6 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.12 EMR67846.1 - 3.7 6.9 27.5 0.15 11.5 12.8 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 EMR67846.1 - 6.2 5.5 9.3 13 4.4 0.2 2.1 2 0 0 2 2 2 0 Presenilin Cu_amine_oxid PF01179.20 EMR67847.1 - 3.4e-128 428.1 0.1 5.4e-114 381.3 0.0 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EMR67847.1 - 0.0012 19.0 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Methyltransf_2 PF00891.18 EMR67848.1 - 1.4e-15 57.2 0.0 2.5e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EMR67848.1 - 0.0011 18.9 0.0 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 Dimerisation domain HTH_IclR PF09339.10 EMR67848.1 - 0.0016 18.2 0.0 0.0054 16.5 0.0 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 EMR67848.1 - 0.0059 16.4 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.16 EMR67848.1 - 0.012 15.1 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EMR67848.1 - 0.018 14.7 0.1 0.072 12.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.6 EMR67848.1 - 0.09 12.3 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Glyco_hydro_3_C PF01915.22 EMR67849.1 - 1.1e-45 156.1 0.0 2.1e-45 155.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR67849.1 - 1.8e-42 145.9 0.0 2.6e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR67849.1 - 2.3e-24 85.3 0.2 4.3e-24 84.4 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.18 EMR67850.1 - 0.00035 19.7 0.1 0.00042 19.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2474 PF10617.9 EMR67850.1 - 6.3 6.7 7.4 5.6 6.9 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) NESP55 PF06390.12 EMR67851.1 - 0.0036 16.9 10.4 0.0036 16.9 10.4 1.8 2 0 0 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 EMR67851.1 - 0.18 11.8 6.3 0.36 10.8 6.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Kelch_5 PF13854.6 EMR67852.1 - 4.9e-12 45.6 2.4 4.9e-12 45.6 2.4 4.5 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 EMR67852.1 - 0.19 11.4 8.1 1.2 8.8 0.0 4.1 4 0 0 4 4 4 0 Kelch motif DUF4381 PF14316.6 EMR67852.1 - 0.26 11.5 0.9 0.52 10.5 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PetG PF02529.15 EMR67852.1 - 0.41 10.5 1.5 0.84 9.5 1.5 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF1771 PF08590.10 EMR67853.1 - 0.018 15.4 3.6 0.031 14.6 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Smr PF01713.21 EMR67853.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Smr domain Epimerase PF01370.21 EMR67854.1 - 6.1e-21 75.0 0.0 1.3e-20 73.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR67854.1 - 7.9e-10 38.2 0.0 1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMR67854.1 - 5.4e-07 29.7 0.0 2.7e-06 27.4 0.0 2.2 2 1 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR67854.1 - 5.4e-06 26.0 0.1 1.4e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMR67854.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EMR67854.1 - 0.018 14.5 0.2 0.046 13.2 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Band_7 PF01145.25 EMR67855.1 - 1e-12 48.5 0.1 1e-12 48.5 0.1 2.8 2 1 0 2 2 2 1 SPFH domain / Band 7 family PHC2_SAM_assoc PF16616.5 EMR67855.1 - 2.6 8.9 7.9 0.34 11.7 2.0 2.1 1 1 1 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 NPC1_N PF16414.5 EMR67856.1 - 1.1e-79 267.5 9.3 1.5e-79 267.0 9.3 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EMR67856.1 - 6e-78 262.8 10.5 3.2e-77 260.4 10.5 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EMR67856.1 - 2.2e-52 177.0 5.3 2.2e-52 177.0 5.3 3.3 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 EMR67856.1 - 6e-06 26.2 0.9 1.2e-05 25.2 0.9 1.4 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.15 EMR67856.1 - 8.8e-06 24.9 5.9 8.8e-06 24.9 5.9 3.3 4 1 0 4 4 4 1 MMPL family TMEM174 PF15029.6 EMR67856.1 - 0.078 12.7 1.2 0.23 11.2 1.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 174 Cas9-BH PF16593.5 EMR67856.1 - 0.27 11.0 0.6 0.59 9.9 0.6 1.5 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 KCH PF16944.5 EMR67857.1 - 6e-54 183.5 1.7 6.7e-54 183.3 1.7 1.0 1 0 0 1 1 1 1 Fungal potassium channel Sensor PF13796.6 EMR67857.1 - 0.0076 16.3 0.1 0.0084 16.2 0.1 1.2 1 0 0 1 1 1 1 Putative sensor CDK2AP PF09806.9 EMR67858.1 - 0.2 11.7 18.9 0.16 12.0 1.2 3.2 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein Macoilin PF09726.9 EMR67858.1 - 0.48 8.9 10.5 0.083 11.4 3.3 2.0 2 0 0 2 2 2 0 Macoilin family ArgoN PF16486.5 EMR67859.1 - 2.7e-13 50.7 1.1 4e-13 50.2 1.1 1.3 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EMR67859.1 - 4.8e-12 45.4 0.2 1e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain Putative_PNPOx PF01243.20 EMR67860.1 - 7.3e-10 38.9 0.0 3.9e-06 27.0 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase CTP_transf_like PF01467.26 EMR67861.1 - 1.2e-25 90.3 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like p450 PF00067.22 EMR67862.1 - 2.9e-26 92.2 0.0 1.1e-19 70.6 0.0 2.9 2 1 1 3 3 3 3 Cytochrome P450 DUF3843 PF12954.7 EMR67862.1 - 0.052 12.5 0.0 0.45 9.4 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3843) LIP PF03583.14 EMR67864.1 - 8.7e-11 41.7 0.6 0.0001 21.7 0.3 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 EMR67864.1 - 2.7e-10 41.2 8.7 2.7e-10 41.2 8.7 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR67864.1 - 3.7e-08 32.9 0.0 1.2e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR67864.1 - 5.8e-07 29.4 0.3 0.00016 21.4 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR67864.1 - 1.1e-06 28.4 0.0 0.04 13.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 EMR67864.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 EMR67864.1 - 0.1 12.1 0.0 0.48 9.9 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family TauD PF02668.16 EMR67865.1 - 5.1e-49 167.5 0.0 6.2e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_3 PF07859.13 EMR67866.1 - 1.6e-25 90.2 0.0 3.7e-25 89.0 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 EMR67866.1 - 0.029 13.0 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 EMR67866.1 - 0.072 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EMR67866.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.16 EMR67867.1 - 2.3e-29 102.5 27.9 2.7e-29 102.2 27.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.21 EMR67868.1 - 7.2e-13 48.4 6.5 1.1e-12 47.8 6.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GMC_oxred_N PF00732.19 EMR67869.1 - 4e-59 200.4 0.0 6.7e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR67869.1 - 9.9e-32 110.4 0.0 1.6e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMR67869.1 - 2.9e-06 26.6 0.3 5.8e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR67869.1 - 0.00022 20.4 0.1 0.0031 16.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EMR67869.1 - 0.0027 17.0 0.2 0.0062 15.8 0.1 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EMR67869.1 - 0.015 15.5 0.1 0.041 14.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EMR67869.1 - 0.035 13.0 0.1 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EMR67869.1 - 0.046 12.9 0.1 0.097 11.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR67869.1 - 0.081 12.1 0.1 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EMR67869.1 - 0.14 10.8 0.2 0.26 9.9 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein APG17 PF04108.12 EMR67870.1 - 1.8e-130 435.6 2.5 2.1e-130 435.4 2.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF2316 PF10078.9 EMR67870.1 - 0.017 15.4 0.4 0.049 13.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) HOIP-UBA PF16678.5 EMR67870.1 - 0.029 14.4 2.1 0.78 9.7 0.2 2.9 2 1 0 2 2 2 0 HOIP UBA domain pair KxDL PF10241.9 EMR67870.1 - 0.032 14.5 3.4 0.35 11.2 0.6 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein APP_E2 PF12925.7 EMR67870.1 - 10 5.8 7.4 32 4.2 0.2 3.2 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein Flavokinase PF01687.17 EMR67871.1 - 6.2e-12 45.8 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase Ferric_reduct PF01794.19 EMR67872.1 - 1.7e-19 70.2 10.0 4.8e-19 68.7 10.0 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMR67872.1 - 1e-08 35.2 0.0 0.00012 22.1 0.1 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 EMR67872.1 - 0.016 15.4 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain TssN PF17555.2 EMR67872.1 - 2.6 7.4 8.3 3.9 6.8 8.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN KR PF08659.10 EMR67873.1 - 1.4e-25 90.3 0.2 3.1e-25 89.1 0.2 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EMR67873.1 - 1.1e-20 74.2 0.0 3.2e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EMR67873.1 - 5.3e-19 69.6 0.0 5.7e-18 66.3 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR67873.1 - 1.5e-16 60.6 0.4 1.2e-15 57.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 EMR67873.1 - 2.4e-11 44.1 0.0 2e-10 41.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EMR67873.1 - 2.7e-11 43.6 0.1 7.8e-11 42.2 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EMR67873.1 - 2.8e-11 44.0 0.1 4.9e-10 40.0 0.0 3.3 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR67873.1 - 2.8e-09 36.9 0.0 8.8e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR67873.1 - 6.6e-09 35.8 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR67873.1 - 8.7e-08 31.8 0.0 2.2e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 EMR67873.1 - 0.0032 17.2 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_33 PF10017.9 EMR67873.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent PCMT PF01135.19 EMR67873.1 - 0.11 12.2 0.0 23 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EMR67873.1 - 0.14 11.8 0.1 1 9.1 0.0 2.3 2 1 0 2 2 2 0 Lysine methyltransferase GST_N PF02798.20 EMR67874.1 - 1.8e-09 37.8 0.0 3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMR67874.1 - 2.7e-08 34.0 0.0 5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR67874.1 - 1.9e-05 25.0 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR67874.1 - 5.9e-05 23.2 0.0 0.00014 22.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR67874.1 - 0.0002 21.5 0.0 0.00033 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR67874.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_1 PF00561.20 EMR67875.1 - 1.4e-12 47.8 0.1 1.8e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR67875.1 - 1.8e-07 32.0 6.9 2.4e-07 31.6 6.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR67875.1 - 3.7e-05 23.1 0.0 5.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMR67875.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 EMR67875.1 - 0.054 13.1 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Cu-oxidase_2 PF07731.14 EMR67876.1 - 3.5e-27 94.8 2.0 6.3e-24 84.3 0.7 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMR67876.1 - 1.5e-17 63.7 0.5 3.6e-17 62.5 0.0 2.0 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EMR67876.1 - 0.00011 22.4 0.0 0.00051 20.2 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase adh_short PF00106.25 EMR67878.1 - 1.8e-26 92.8 2.1 1e-14 54.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67878.1 - 3.1e-21 76.0 1.3 2.7e-10 40.2 0.0 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67878.1 - 6.2e-06 26.2 1.6 0.00039 20.4 0.0 2.9 2 1 0 2 2 2 1 KR domain Amidase PF01425.21 EMR67879.1 - 2.8e-74 250.7 0.1 8.7e-74 249.1 0.1 1.7 1 1 0 1 1 1 1 Amidase PHD PF00628.29 EMR67880.1 - 4.3e-10 39.3 5.3 4.3e-10 39.3 5.3 1.7 2 0 0 2 2 2 1 PHD-finger zf-SNAP50_C PF12251.8 EMR67880.1 - 0.053 13.2 1.8 0.093 12.4 1.8 1.3 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal PHD_2 PF13831.6 EMR67880.1 - 0.18 11.4 3.8 0.31 10.6 3.8 1.4 1 0 0 1 1 1 0 PHD-finger UIM PF02809.20 EMR67880.1 - 0.61 10.1 11.0 0.033 14.1 4.1 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif Pex14_N PF04695.13 EMR67881.1 - 1.1 9.9 10.3 0.57 10.8 3.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CAP_N PF01213.19 EMR67881.1 - 5.8 6.3 9.7 0.096 12.2 2.4 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MMR_HSR1 PF01926.23 EMR67882.1 - 7.7e-11 42.1 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EMR67882.1 - 0.0029 17.7 0.0 0.098 12.7 0.0 2.3 1 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EMR67882.1 - 0.0087 16.0 0.0 2.1 8.2 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EMR67882.1 - 0.0095 16.3 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EMR67882.1 - 0.017 14.7 0.0 0.056 13.0 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 EMR67882.1 - 0.035 14.7 0.0 0.087 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 EMR67882.1 - 0.069 12.2 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Arf PF00025.21 EMR67882.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family E1-E2_ATPase PF00122.20 EMR67884.1 - 2.3e-32 112.0 12.0 1.4e-22 80.1 0.3 4.0 5 0 0 5 5 5 2 E1-E2 ATPase Hydrolase PF00702.26 EMR67884.1 - 1e-18 68.4 0.1 2e-18 67.4 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMR67884.1 - 5.4e-13 48.4 1.4 7.3e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMR67884.1 - 0.0036 17.1 0.1 0.0078 16.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GNVR PF13807.6 EMR67884.1 - 0.058 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase RRM_1 PF00076.22 EMR67886.1 - 3.1e-23 81.4 0.0 7.2e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Yae1_N PF09811.9 EMR67886.1 - 4.3e-12 45.5 3.9 4.3e-12 45.5 3.9 2.1 2 0 0 2 2 2 1 Essential protein Yae1, N terminal HA2 PF04408.23 EMR67889.1 - 1.9e-23 82.8 0.1 1.9e-23 82.8 0.1 2.9 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EMR67889.1 - 2.8e-23 82.1 0.0 5.6e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EMR67889.1 - 2.9e-13 50.1 0.0 9.9e-13 48.4 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EMR67889.1 - 1.1e-12 48.2 0.3 2.3e-12 47.1 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 EMR67889.1 - 1.5e-05 25.3 0.2 4.2e-05 23.9 0.1 1.9 2 0 0 2 2 1 1 AAA domain DEAD PF00270.29 EMR67889.1 - 1.9e-05 24.5 0.6 4.7e-05 23.2 0.6 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EMR67889.1 - 0.00037 19.7 0.0 0.00077 18.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EMR67889.1 - 0.00067 19.4 0.0 0.002 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EMR67889.1 - 0.0034 16.7 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EMR67889.1 - 0.0065 16.8 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMR67889.1 - 0.0083 16.6 0.5 0.17 12.4 0.2 3.0 2 1 1 3 3 3 1 ABC transporter AAA_16 PF13191.6 EMR67889.1 - 0.016 15.6 0.4 0.071 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EMR67889.1 - 0.046 13.4 0.4 0.13 11.9 0.4 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 EMR67889.1 - 0.059 12.8 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 EMR67889.1 - 0.064 13.3 0.1 0.49 10.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EMR67889.1 - 0.071 12.5 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase PF06745.13 EMR67889.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Herpes_ori_bp PF02399.15 EMR67889.1 - 0.19 9.8 0.0 0.29 9.1 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Abhydrolase_4 PF08386.10 EMR67890.1 - 1.3e-19 70.3 0.0 1.6e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 TAP-like protein p450 PF00067.22 EMR67891.1 - 1.4e-15 57.0 0.0 1.5e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 EMR67892.1 - 2.2e-13 51.3 0.0 2.7e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR67892.1 - 0.00016 21.0 0.0 0.067 12.5 0.0 2.4 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR67892.1 - 0.00051 19.8 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EMR67892.1 - 0.011 15.6 0.1 0.029 14.2 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EMR67892.1 - 0.038 13.8 0.1 0.081 12.7 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 EMR67893.1 - 4.3e-06 26.2 0.0 5.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EMR67893.1 - 0.00045 19.4 0.0 0.00064 18.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pro-rich PF15240.6 EMR67894.1 - 3.6 7.8 57.3 12 6.1 57.3 1.7 1 1 0 1 1 1 0 Proline-rich adh_short PF00106.25 EMR67895.1 - 4.5e-21 75.2 0.6 3.4e-09 36.5 0.0 3.3 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67895.1 - 2.4e-12 46.9 0.0 2e-06 27.6 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR67897.1 - 4e-31 108.3 0.1 7e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 EMR67897.1 - 1.8e-09 37.8 0.0 3.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site FSH1 PF03959.13 EMR67898.1 - 1.6e-27 96.6 0.0 2.4e-27 96.0 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EMR67898.1 - 2e-07 31.9 0.1 3.2e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 EMR67898.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Ketoacyl-synt_C PF02801.22 EMR67899.1 - 1.2e-33 115.6 0.0 1.6e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EMR67899.1 - 1.1e-08 34.9 0.1 2.1e-08 34.1 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Peroxidase_2 PF01328.17 EMR67900.1 - 4.6e-48 164.2 0.1 6.1e-48 163.8 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DIX PF00778.17 EMR67900.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 DIX domain Sin3a_C PF16879.5 EMR67901.1 - 1.1e-75 255.0 4.2 2.7e-75 253.7 2.8 2.4 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 EMR67901.1 - 4.8e-47 157.9 6.9 1e-17 63.9 0.0 4.4 4 1 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EMR67901.1 - 3.4e-37 126.5 0.2 1.2e-36 124.7 0.0 2.1 2 0 0 2 2 2 1 Sin3 family co-repressor Pollen_allerg_1 PF01357.21 EMR67901.1 - 0.13 12.3 0.4 0.39 10.8 0.2 1.9 2 0 0 2 2 2 0 Pollen allergen WD40 PF00400.32 EMR67903.1 - 2.1e-18 66.3 3.9 0.00092 20.0 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR67903.1 - 3.7e-12 46.4 0.1 0.00037 20.7 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMR67903.1 - 5e-05 23.3 0.2 0.014 15.3 0.1 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EMR67903.1 - 0.0028 16.8 0.1 0.012 14.7 0.1 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40_like PF17005.5 EMR67903.1 - 0.019 14.3 0.1 0.071 12.4 0.1 1.9 2 0 0 2 2 2 0 WD40-like domain Fungal_trans_2 PF11951.8 EMR67904.1 - 0.0051 15.7 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sun2_CC2 PF18580.1 EMR67904.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 NAD_binding_10 PF13460.6 EMR67905.1 - 0.00066 19.6 0.1 0.014 15.3 0.1 2.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR67905.1 - 0.0078 15.8 0.0 0.016 14.8 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family Thiolase_N PF00108.23 EMR67906.1 - 5.3e-92 307.9 1.7 5.3e-92 307.9 1.7 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMR67906.1 - 2.5e-46 156.3 0.3 2.5e-46 156.3 0.3 2.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMR67906.1 - 0.00025 20.7 0.8 0.00025 20.7 0.8 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EMR67906.1 - 0.17 11.8 5.6 0.99 9.3 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LIN52 PF10044.9 EMR67907.1 - 9.7e-06 26.2 0.1 27 5.6 0.0 8.0 5 3 5 10 10 10 0 Retinal tissue protein MauJ PF17419.2 EMR67907.1 - 0.007 15.9 0.5 13 5.1 0.0 4.7 2 1 3 5 5 5 1 Methylamine utilization protein MauJ Antimicrobial_7 PF08102.11 EMR67907.1 - 0.07 13.4 1.2 41 4.5 0.0 4.0 3 0 0 3 3 3 0 Scorpion antimicrobial peptide Adaptin_N PF01602.20 EMR67907.1 - 0.11 11.0 0.4 43 2.5 0.0 3.5 2 1 0 3 3 3 0 Adaptin N terminal region FlgN PF05130.12 EMR67907.1 - 0.19 12.2 3.6 7.4 7.1 0.0 4.1 2 1 0 3 3 3 0 FlgN protein DUF4423 PF14394.6 EMR67907.1 - 0.2 11.3 1.6 22 4.7 0.0 4.1 4 1 2 6 6 6 0 Domain of unknown function (DUF4423) Campylo_MOMP PF05538.11 EMR67907.1 - 0.68 8.9 1.8 1.3e+02 1.3 0.0 4.3 6 0 0 6 6 6 0 Campylobacter major outer membrane protein DUF3368 PF11848.8 EMR67907.1 - 1.8 8.4 38.3 2.3 8.1 0.0 15.9 19 0 0 19 19 19 0 Domain of unknown function (DUF3368) GMC_oxred_C PF05199.13 EMR67908.1 - 5e-30 104.9 0.1 8.5e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR67908.1 - 8.8e-24 84.4 0.7 2.2e-14 53.6 0.2 2.9 1 1 0 2 2 2 2 GMC oxidoreductase Epimerase PF01370.21 EMR67909.1 - 2e-09 37.3 0.1 1.4e-08 34.5 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMR67909.1 - 0.0099 15.1 0.0 0.025 13.8 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 EMR67909.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EMR67909.1 - 0.017 14.7 0.5 0.037 13.6 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family Semialdhyde_dh PF01118.24 EMR67909.1 - 0.026 14.9 0.0 0.06 13.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 EMR67910.1 - 5.2e-18 65.1 0.2 1.3e-17 63.8 0.2 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 EMR67910.1 - 3e-15 57.1 0.0 6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_60s PF00428.19 EMR67911.1 - 4.6 7.9 11.4 0.61 10.7 3.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein GTP_EFTU PF00009.27 EMR67913.1 - 4.2e-46 157.0 0.0 6.3e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EMR67913.1 - 4e-37 127.5 7.1 8.3e-37 126.5 7.1 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EMR67913.1 - 1.2e-18 67.0 0.0 7.4e-18 64.5 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EMR67913.1 - 5.7e-18 64.7 0.0 1.5e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EMR67913.1 - 2e-07 31.0 0.1 9.6e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EMR67913.1 - 2.8e-07 30.8 0.0 6.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMR67913.1 - 0.00031 20.8 0.1 0.00062 19.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase adh_short_C2 PF13561.6 EMR67914.1 - 1.3e-26 93.6 0.1 2.1e-26 92.9 0.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR67914.1 - 1.6e-17 63.6 0.2 2.2e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR67914.1 - 2e-07 31.1 0.0 3.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 KR domain PK_C PF02887.16 EMR67914.1 - 0.034 14.4 1.3 9.1 6.5 0.0 2.6 2 1 1 3 3 3 0 Pyruvate kinase, alpha/beta domain Glyco_tran_WecB PF03808.13 EMR67914.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Rad51 PF08423.11 EMR67915.1 - 0.0027 17.0 0.0 0.0032 16.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 DUF1768 PF08719.11 EMR67916.1 - 2.2e-53 180.8 0.0 2.7e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) NAD_binding_1 PF00175.21 EMR67917.1 - 2.7e-30 105.2 0.0 5.8e-30 104.1 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMR67917.1 - 2.9e-23 82.1 0.0 5.8e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EMR67917.1 - 3.2e-07 30.6 0.0 0.0013 18.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EMR67917.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain AstE_AspA PF04952.14 EMR67918.1 - 5e-31 107.9 0.0 6.6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family RnfC_N PF13375.6 EMR67918.1 - 0.014 15.4 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain MFS_1 PF07690.16 EMR67920.1 - 1.9e-32 112.5 13.7 2.7e-32 112.1 13.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3712 PF12505.8 EMR67922.1 - 8.5e-27 93.9 0.3 8.5e-27 93.9 0.3 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) Glyco_transf_28 PF03033.20 EMR67923.1 - 9.1e-23 80.8 0.0 1.7e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EMR67923.1 - 5.9e-05 22.1 0.0 9.1e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 EMR67923.1 - 0.2 11.4 0.3 0.46 10.2 0.3 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Hamartin PF04388.12 EMR67923.1 - 0.21 10.2 5.1 0.29 9.7 5.1 1.1 1 0 0 1 1 1 0 Hamartin protein Zip PF02535.22 EMR67923.1 - 0.31 10.2 3.0 0.46 9.7 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 EMR67923.1 - 5 6.5 7.2 8.1 5.8 7.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ABC_tran PF00005.27 EMR67924.1 - 5.8e-50 169.4 0.0 2.5e-28 99.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR67924.1 - 2e-42 145.8 15.9 9.7e-27 94.3 7.8 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EMR67924.1 - 3.2e-07 30.0 2.7 0.38 10.2 0.4 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMR67924.1 - 1.4e-05 25.5 0.8 0.0035 17.7 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EMR67924.1 - 0.00055 20.0 0.3 0.044 13.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 EMR67924.1 - 0.00063 18.9 0.0 0.038 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 EMR67924.1 - 0.00078 20.0 0.8 0.082 13.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EMR67924.1 - 0.00095 19.1 0.2 0.99 9.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EMR67924.1 - 0.0022 17.7 2.1 0.29 10.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMR67924.1 - 0.0048 17.2 0.0 7.2 6.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EMR67924.1 - 0.0059 16.2 0.0 1.2 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EMR67924.1 - 0.02 15.0 3.3 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 EMR67924.1 - 0.032 14.0 0.2 12 5.6 0.3 3.5 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 EMR67924.1 - 0.052 12.8 0.2 0.89 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 EMR67924.1 - 0.066 12.5 0.2 6.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 EMR67924.1 - 0.068 13.4 0.1 11 6.4 0.0 3.5 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EMR67924.1 - 0.069 12.9 1.0 8 6.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 EMR67924.1 - 0.13 11.2 0.1 0.27 10.2 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EMR67924.1 - 0.37 10.8 1.5 28 4.8 0.5 2.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MFS_1 PF07690.16 EMR67926.1 - 2.1e-37 128.9 24.4 2.1e-37 128.9 24.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR67926.1 - 0.00027 19.9 1.5 0.00027 19.9 1.5 1.8 2 1 0 2 2 2 1 MFS_1 like family ESSS PF10183.9 EMR67926.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3671 PF12420.8 EMR67926.1 - 0.096 12.8 7.7 0.75 9.9 0.5 3.8 3 1 0 3 3 3 0 Protein of unknown function zf-H2C2_2 PF13465.6 EMR67928.1 - 1.1e-10 41.4 23.3 0.00039 20.7 0.4 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 EMR67928.1 - 1.1e-10 41.3 18.3 0.0012 19.1 0.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR67928.1 - 9.8e-07 29.1 16.4 0.0063 17.3 0.4 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 EMR67928.1 - 0.0014 18.9 7.6 0.062 13.7 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EMR67928.1 - 0.0046 17.1 0.8 0.27 11.4 0.1 2.3 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2_3rep PF18868.1 EMR67928.1 - 0.014 16.1 1.5 0.44 11.2 0.1 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 EMR67928.1 - 0.028 14.2 0.2 0.21 11.4 0.1 2.3 2 0 0 2 2 2 0 GAGA factor C1_4 PF07975.12 EMR67928.1 - 0.13 12.5 0.6 0.36 11.1 0.6 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 EMR67928.1 - 0.2 11.7 12.6 0.27 11.3 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMR67928.1 - 0.35 11.2 5.0 1.4 9.3 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Cyclin_N PF00134.23 EMR67929.1 - 3.7e-43 146.3 0.0 2e-42 144.0 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMR67929.1 - 1.5e-35 121.8 0.0 2.6e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.18 EMR67931.1 - 5.1e-51 172.1 4.1 1.4e-50 170.8 3.4 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EMR67931.1 - 2.2e-25 88.4 1.1 9.1e-25 86.4 0.5 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain TYA PF01021.19 EMR67931.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 TYA transposon protein Proteasome PF00227.26 EMR67932.1 - 6.1e-47 159.6 0.0 7.7e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EMR67932.1 - 2.9e-14 52.2 0.2 2.9e-14 52.2 0.2 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal MFS_1 PF07690.16 EMR67935.1 - 2.9e-31 108.7 33.4 2.9e-31 108.7 33.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EMR67935.1 - 0.0013 17.1 0.4 0.0013 17.1 0.4 2.3 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family NUP214 PF16755.5 EMR67936.1 - 0.00015 21.2 0.0 0.00073 18.9 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 EMR67936.1 - 0.014 15.6 0.0 0.046 14.0 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF812 PF05667.11 EMR67936.1 - 0.06 12.2 0.5 0.091 11.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ABA_GPCR PF12430.8 EMR67937.1 - 1e-59 201.3 0.3 1e-59 201.3 0.3 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EMR67937.1 - 2.5e-26 91.5 0.1 1.5e-25 89.0 0.0 2.3 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF2157 PF09925.9 EMR67937.1 - 0.093 12.5 8.3 1 9.2 0.4 3.7 2 2 1 3 3 3 0 Predicted membrane protein (DUF2157) MRP-L46 PF11788.8 EMR67938.1 - 3.3e-28 98.8 0.1 2.3e-27 96.1 0.0 2.2 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 EMR67938.1 - 0.071 13.2 0.1 0.17 11.9 0.1 1.7 1 1 0 1 1 1 0 NUDIX domain PEX11 PF05648.14 EMR67939.1 - 9.7e-05 21.9 2.1 0.05 13.1 0.0 3.1 3 0 0 3 3 3 3 Peroxisomal biogenesis factor 11 (PEX11) Pyr_redox_2 PF07992.14 EMR67940.1 - 7.1e-53 179.7 0.1 9.1e-53 179.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR67940.1 - 3.9e-12 46.5 0.2 2.7e-10 40.7 0.2 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR67940.1 - 0.0012 18.1 0.5 0.27 10.4 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 EMR67940.1 - 0.078 12.6 0.6 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal NAD_binding_8 PF13450.6 EMR67940.1 - 0.13 12.5 0.0 22 5.4 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Peptidase_M16_C PF05193.21 EMR67941.1 - 7.6e-55 185.8 0.0 1.4e-54 184.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMR67941.1 - 2.9e-40 137.7 0.0 6e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) CTU2 PF10288.9 EMR67942.1 - 3.3e-11 43.4 6.3 2.2e-10 40.7 0.0 4.4 5 1 0 5 5 5 1 Cytoplasmic tRNA 2-thiolation protein 2 Ribosomal_60s PF00428.19 EMR67942.1 - 0.068 13.8 11.6 0.13 12.9 4.4 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 EMR67942.1 - 0.16 12.4 0.7 0.49 10.8 0.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Abhydrolase_6 PF12697.7 EMR67943.1 - 1.5e-08 35.6 0.0 2.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR67943.1 - 4.2e-07 29.9 0.0 0.00055 19.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR67943.1 - 0.0015 17.8 0.0 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 EMR67943.1 - 0.095 12.2 0.0 5.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Acetyltransf_1 PF00583.25 EMR67944.1 - 6.3e-09 36.1 0.0 1.3e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR67944.1 - 3.1e-08 33.9 0.0 6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR67944.1 - 9.5e-08 32.0 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR67944.1 - 0.00013 22.0 0.0 0.04 14.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR67944.1 - 0.00029 20.9 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EMR67944.1 - 0.0053 16.7 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Mito_carr PF00153.27 EMR67945.1 - 1.3e-55 185.3 1.0 3e-19 68.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CorA PF01544.18 EMR67946.1 - 3.2e-06 26.7 4.9 3.2e-06 26.7 4.9 2.9 3 1 0 3 3 3 1 CorA-like Mg2+ transporter protein PHF5 PF03660.14 EMR67947.1 - 5e-52 174.5 10.5 5.7e-52 174.3 10.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EMR67947.1 - 0.69 7.7 7.7 0.73 7.6 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EMR67947.1 - 3.1 7.9 16.0 6.1 6.9 2.1 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 EMR67948.1 - 9.8e-32 109.7 13.3 9.8e-32 109.7 13.3 2.5 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 EMR67948.1 - 0.00046 20.4 6.4 0.00046 20.4 6.4 3.9 2 2 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif DUF2461 PF09365.10 EMR67949.1 - 0.089 12.7 0.1 0.089 12.7 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) Hamartin PF04388.12 EMR67949.1 - 0.16 10.6 3.0 0.2 10.3 3.0 1.1 1 0 0 1 1 1 0 Hamartin protein PA26 PF04636.13 EMR67949.1 - 0.46 9.3 1.2 0.68 8.8 1.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 EMR67949.1 - 5.4 6.8 8.5 8.6 6.1 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAGA-Tad1 PF12767.7 EMR67949.1 - 6.8 6.4 9.3 6.9 6.3 6.5 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Nucleo_P87 PF07267.11 EMR67949.1 - 8.4 5.1 6.7 13 4.5 6.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LIG3_BRCT PF16759.5 EMR67950.1 - 4.5e-05 23.7 0.1 9.6e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 EMR67950.1 - 6.6e-05 23.2 0.0 0.00016 22.0 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EMR67950.1 - 0.0036 17.7 0.0 0.0087 16.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EMR67950.1 - 0.0055 16.6 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain DUF680 PF05079.12 EMR67950.1 - 0.5 11.1 5.6 0.27 11.9 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF680) PhoLip_ATPase_C PF16212.5 EMR67951.1 - 9.5e-42 143.5 16.9 1.4e-26 93.8 7.4 3.4 3 1 1 4 4 4 2 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMR67951.1 - 1.3e-27 95.2 5.9 3.3e-27 94.0 5.9 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EMR67951.1 - 2.5e-11 43.5 0.1 4.6e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMR67951.1 - 3.4e-11 43.8 1.3 4.7e-06 27.0 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EMR67951.1 - 2.7e-09 36.8 0.1 6.4e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EMR67951.1 - 0.00033 20.5 0.2 0.0011 18.8 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 EMR67952.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like KASH_CCD PF14662.6 EMR67953.1 - 0.0081 16.0 1.5 0.014 15.3 1.5 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 EMR67953.1 - 0.067 13.3 1.3 0.17 12.0 1.3 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 EMR67953.1 - 0.084 12.7 1.4 0.21 11.4 1.4 1.6 1 0 0 1 1 1 0 Septum formation initiator Syntaxin PF00804.25 EMR67953.1 - 0.15 11.7 0.4 0.24 11.1 0.4 1.3 1 0 0 1 1 1 0 Syntaxin HALZ PF02183.18 EMR67953.1 - 0.55 10.5 3.5 0.48 10.7 0.7 2.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper MFS_1 PF07690.16 EMR67956.1 - 5.4e-17 61.8 10.4 5.4e-17 61.8 10.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Wzy_C PF04932.15 EMR67956.1 - 0.053 13.2 1.2 0.92 9.1 0.4 2.3 2 1 0 2 2 2 0 O-Antigen ligase Prefoldin_2 PF01920.20 EMR67957.1 - 7.8e-21 74.0 11.8 1e-20 73.6 11.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EMR67957.1 - 0.00068 19.6 9.3 0.0013 18.6 0.4 2.4 2 1 0 2 2 2 1 Prefoldin subunit MIP-T3_C PF17749.1 EMR67957.1 - 0.0057 16.6 3.1 0.0057 16.6 3.1 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Prefoldin_3 PF13758.6 EMR67957.1 - 0.0061 16.6 6.0 0.008 16.2 6.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit COG5 PF10392.9 EMR67957.1 - 0.012 15.8 1.9 3.4 7.9 0.1 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 HBM PF16591.5 EMR67957.1 - 0.013 14.9 3.3 0.013 14.9 3.3 1.9 2 0 0 2 2 2 0 Helical bimodular sensor domain NPV_P10 PF05531.12 EMR67957.1 - 0.014 15.9 4.2 0.93 10.0 0.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RmuC PF02646.16 EMR67957.1 - 0.02 14.0 4.3 0.3 10.2 0.9 2.0 2 0 0 2 2 2 0 RmuC family CHGN PF05679.16 EMR67957.1 - 0.024 13.5 2.3 0.031 13.1 2.3 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Laminin_II PF06009.12 EMR67957.1 - 0.055 13.5 3.7 2.3 8.3 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II FliD_C PF07195.12 EMR67957.1 - 0.056 12.9 4.2 0.12 11.8 4.2 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ABC_tran_CTD PF16326.5 EMR67957.1 - 0.069 13.4 11.4 0.71 10.2 1.8 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain LPP PF04728.13 EMR67957.1 - 0.084 13.3 5.9 3.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Swi5 PF07061.11 EMR67957.1 - 0.096 12.8 7.3 1 9.5 2.0 2.3 2 0 0 2 2 2 0 Swi5 Rx_N PF18052.1 EMR67957.1 - 0.11 12.8 6.5 2 8.8 2.3 2.2 2 0 0 2 2 2 0 Rx N-terminal domain DUF4407 PF14362.6 EMR67957.1 - 0.11 11.9 8.4 0.16 11.3 8.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 EMR67957.1 - 0.11 12.8 10.5 0.28 11.5 10.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) CENP-F_N PF10481.9 EMR67957.1 - 0.13 11.9 8.8 1.1 8.9 8.8 1.9 1 1 0 1 1 1 0 Cenp-F N-terminal domain DivIC PF04977.15 EMR67957.1 - 0.13 12.1 18.1 4.1 7.3 1.2 3.2 2 1 0 2 2 2 0 Septum formation initiator Nup88 PF10168.9 EMR67957.1 - 0.13 10.0 10.1 0.16 9.7 10.1 1.0 1 0 0 1 1 1 0 Nuclear pore component Rh5 PF18515.1 EMR67957.1 - 0.14 11.5 2.9 0.16 11.2 2.9 1.2 1 1 0 1 1 1 0 Rh5 coiled-coil domain FlaC_arch PF05377.11 EMR67957.1 - 0.16 12.4 7.7 1.3 9.5 0.7 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) WEMBL PF05701.11 EMR67957.1 - 0.16 10.6 10.4 0.28 9.8 10.3 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.7 EMR67957.1 - 0.17 12.0 11.3 1.1 9.5 1.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 EMR67957.1 - 0.18 10.7 14.0 0.4 9.5 14.0 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 EMR67957.1 - 0.19 11.8 4.8 1.5 8.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 EMR67957.1 - 0.2 11.7 9.1 2.9 8.0 0.4 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HalX PF08663.10 EMR67957.1 - 0.25 11.7 5.4 1.6 9.1 0.1 2.5 2 1 0 2 2 2 0 HalX domain MutS_IV PF05190.18 EMR67957.1 - 0.26 11.7 4.1 3.1 8.2 0.1 2.2 2 0 0 2 2 2 0 MutS family domain IV OmpH PF03938.14 EMR67957.1 - 0.27 11.6 19.1 6.6 7.1 2.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FliJ PF02050.16 EMR67957.1 - 0.37 11.0 12.8 0.45 10.7 0.7 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Rho_Binding PF08912.11 EMR67957.1 - 0.39 11.6 10.9 0.46 11.3 0.3 2.5 2 1 0 2 2 2 0 Rho Binding DUF4164 PF13747.6 EMR67957.1 - 0.39 11.0 9.0 1 9.7 3.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) COG2 PF06148.11 EMR67957.1 - 0.42 10.7 5.7 5.8 7.0 0.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 EMR67957.1 - 0.43 10.6 11.4 1.4 9.0 4.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF677 PF05055.12 EMR67957.1 - 0.49 9.2 5.5 0.88 8.4 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF677) SKA2 PF16740.5 EMR67957.1 - 0.5 10.2 11.5 0.64 9.8 4.6 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF1640 PF07798.11 EMR67957.1 - 0.5 10.4 10.0 0.95 9.5 10.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) TMPIT PF07851.13 EMR67957.1 - 0.52 9.5 6.1 0.63 9.2 6.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein JIP_LZII PF16471.5 EMR67957.1 - 0.58 10.4 7.0 0.94 9.7 1.7 2.4 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Occludin_ELL PF07303.13 EMR67957.1 - 0.63 10.8 5.6 1.5 9.6 1.4 2.1 2 0 0 2 2 2 0 Occludin homology domain End3 PF12761.7 EMR67957.1 - 0.8 9.8 9.9 0.95 9.6 9.9 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 THOC7 PF05615.13 EMR67957.1 - 0.92 9.8 11.6 0.59 10.4 1.3 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 ZnuA PF01297.17 EMR67957.1 - 1.1 8.6 3.8 0.92 8.9 0.1 1.9 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic DHR10 PF18595.1 EMR67957.1 - 1.2 9.2 13.1 3.2 7.8 1.1 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain MtrG PF04210.13 EMR67957.1 - 1.5 8.7 4.7 1.3 8.9 1.8 2.3 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G FapA PF03961.13 EMR67957.1 - 1.6 7.3 11.7 6.4 5.3 11.7 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 EMR67957.1 - 1.6 9.3 16.3 3.5 8.2 7.2 2.1 1 1 0 2 2 2 0 Apg6 coiled-coil region Tektin PF03148.14 EMR67957.1 - 1.7 7.3 11.5 1.5 7.5 1.8 2.0 2 0 0 2 2 2 0 Tektin family SKA1 PF07160.12 EMR67957.1 - 1.8 8.4 10.7 2.2 8.1 3.3 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 PHM7_cyt PF14703.6 EMR67957.1 - 1.8 8.8 9.6 4.3 7.5 9.6 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Muted PF14942.6 EMR67957.1 - 1.8 8.9 12.0 2.9 8.3 1.0 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Spc24 PF08286.11 EMR67957.1 - 2.2 8.6 9.3 2.8 8.2 2.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cep57_MT_bd PF06657.13 EMR67957.1 - 2.5 8.6 9.5 5.8 7.5 3.2 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4140 PF13600.6 EMR67957.1 - 2.6 8.5 11.8 4.9 7.6 1.0 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.6 EMR67957.1 - 2.7 8.0 16.8 1.7 8.7 2.6 2.2 2 0 0 2 2 2 0 FlxA-like protein YabA PF06156.13 EMR67957.1 - 2.7 8.7 9.0 82 3.9 8.7 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Uso1_p115_C PF04871.13 EMR67957.1 - 2.8 8.3 13.6 20 5.6 13.6 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF16 PF01519.16 EMR67957.1 - 3 8.4 12.1 0.57 10.7 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Val_tRNA-synt_C PF10458.9 EMR67957.1 - 3 8.2 11.2 0.41 11.0 0.7 2.8 3 0 0 3 3 2 0 Valyl tRNA synthetase tRNA binding arm GrpE PF01025.19 EMR67957.1 - 3.5 7.3 11.6 2.3 7.8 1.5 2.1 2 0 0 2 2 2 0 GrpE DUF812 PF05667.11 EMR67957.1 - 3.6 6.4 13.5 8.4 5.1 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF641 PF04859.12 EMR67957.1 - 3.6 7.9 8.9 7.2 7.0 1.1 2.1 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Cluap1 PF10234.9 EMR67957.1 - 3.7 6.9 11.4 0.29 10.5 1.4 2.0 1 1 0 2 2 2 0 Clusterin-associated protein-1 SlyX PF04102.12 EMR67957.1 - 4.1 8.1 8.5 9.1 7.0 0.1 2.4 2 1 0 2 2 2 0 SlyX YlqD PF11068.8 EMR67957.1 - 5.7 7.3 17.0 8.6 6.7 2.0 2.1 1 1 1 2 2 2 0 YlqD protein DUF4337 PF14235.6 EMR67957.1 - 6.7 6.8 8.6 8.2 6.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) 60KD_IMP PF02096.20 EMR67957.1 - 8.1 6.3 6.6 23 4.8 1.9 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein DUF4315 PF14193.6 EMR67957.1 - 8.2 6.5 13.3 6.1 6.9 3.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) Com_YlbF PF06133.11 EMR67957.1 - 8.6 7.0 14.6 4.2 8.0 7.6 2.2 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA RHS_repeat PF05593.14 EMR67958.1 - 1.3e-15 57.5 62.9 8.7e-06 26.1 0.3 14.5 11 3 5 16 16 16 10 RHS Repeat HRXXH PF13933.6 EMR67958.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase family HSP70 PF00012.20 EMR67959.1 - 2.5e-05 22.7 0.0 0.00027 19.3 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein RAP1 PF07218.11 EMR67960.1 - 1.5 7.0 6.8 2 6.6 6.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.6 EMR67960.1 - 1.8 7.8 8.7 3.3 7.0 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) JAB PF01398.21 EMR67961.1 - 2e-14 53.6 0.0 3.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EMR67961.1 - 6e-06 26.0 0.1 2.1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 EMR67961.1 - 9.6e-06 25.8 0.1 1.8e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain AAA PF00004.29 EMR67962.1 - 8.1e-42 142.8 0.0 1.5e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EMR67962.1 - 2.1e-28 98.1 0.4 1.3e-27 95.6 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EMR67962.1 - 3.2e-22 78.4 9.8 7.5e-22 77.2 9.8 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EMR67962.1 - 3.1e-07 30.1 0.0 2.3e-06 27.3 0.0 2.6 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 EMR67962.1 - 4.1e-05 23.4 0.0 9.9e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EMR67962.1 - 8.5e-05 22.9 0.9 0.016 15.6 0.0 3.1 4 0 0 4 4 3 1 RNA helicase AAA_5 PF07728.14 EMR67962.1 - 0.00012 22.1 0.0 0.00066 19.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EMR67962.1 - 0.00014 21.6 0.0 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EMR67962.1 - 0.00016 21.0 0.0 0.00032 20.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EMR67962.1 - 0.00019 21.8 0.2 0.018 15.4 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EMR67962.1 - 0.00039 20.6 0.4 0.0015 18.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMR67962.1 - 0.00043 20.6 0.1 0.096 13.0 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 EMR67962.1 - 0.00076 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EMR67962.1 - 0.0015 17.7 0.0 0.0054 15.9 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EMR67962.1 - 0.0026 17.9 0.0 0.0096 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EMR67962.1 - 0.0061 16.3 0.1 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMR67962.1 - 0.0075 16.8 0.0 0.032 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EMR67962.1 - 0.0098 15.3 0.2 0.038 13.4 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMR67962.1 - 0.013 15.1 0.2 2.6 7.6 0.1 3.0 1 1 2 3 3 3 0 AAA domain AAA_17 PF13207.6 EMR67962.1 - 0.014 15.8 0.0 0.058 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMR67962.1 - 0.021 14.1 0.4 1 8.6 0.1 3.0 2 1 1 3 3 3 0 Zeta toxin USP8_dimer PF08969.11 EMR67962.1 - 0.021 15.0 7.4 0.035 14.3 5.6 2.1 2 0 0 2 2 2 0 USP8 dimerisation domain AAA_7 PF12775.7 EMR67962.1 - 0.022 14.2 0.0 0.12 11.9 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region Torsin PF06309.11 EMR67962.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Torsin PhoH PF02562.16 EMR67962.1 - 0.065 12.7 0.8 0.12 11.9 0.1 1.7 2 0 0 2 2 1 0 PhoH-like protein NACHT PF05729.12 EMR67962.1 - 0.12 12.3 0.0 0.66 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 EMR67962.1 - 0.13 12.0 0.3 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Cytidylate kinase Parvo_NS1 PF01057.17 EMR67962.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 EMR67962.1 - 0.15 11.9 0.9 1.8 8.4 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EMR67962.1 - 0.16 12.5 1.0 3 8.3 0.0 3.1 3 1 0 3 3 3 0 ABC transporter TPR_1 PF00515.28 EMR67962.1 - 3.1 7.8 5.9 2.7 8.0 3.6 2.2 2 1 0 2 2 1 0 Tetratricopeptide repeat DUF3632 PF12311.8 EMR67964.1 - 1.9e-13 51.3 0.3 5.4e-13 49.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) YchF-GTPase_C PF06071.13 EMR67965.1 - 4.5e-35 119.7 0.1 1.3e-34 118.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EMR67965.1 - 7.5e-17 61.4 0.0 7.1e-16 58.3 0.0 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMR67965.1 - 0.00057 19.4 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EMR67965.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 0 TGS domain AAA_14 PF13173.6 EMR67965.1 - 0.068 13.2 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EMR67965.1 - 0.12 12.8 3.6 3.5 8.1 3.6 2.3 1 1 0 1 1 1 0 AAA domain DNA_pol3_a_NII PF11490.8 EMR67965.1 - 2.8 7.8 7.8 5.1 7.0 0.3 3.2 2 1 1 3 3 3 0 DNA polymerase III polC-type N-terminus II FMO-like PF00743.19 EMR67967.1 - 2.2e-31 108.9 0.0 1e-23 83.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR67967.1 - 2.1e-12 46.9 0.0 2.7e-08 33.4 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR67967.1 - 6.6e-08 32.1 0.0 1.1e-06 28.1 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR67967.1 - 8.4e-05 22.6 0.6 0.00056 19.9 0.2 2.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMR67967.1 - 0.00059 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR67967.1 - 0.0056 15.8 0.2 1.4 7.9 0.1 3.0 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EMR67967.1 - 0.015 14.5 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 EMR67967.1 - 0.044 13.3 1.1 1.1 8.7 0.1 2.9 1 1 1 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR67967.1 - 0.051 14.1 0.0 7.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4062 PF13271.6 EMR67967.1 - 0.059 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) HI0933_like PF03486.14 EMR67967.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NOA36 PF06524.12 EMR67968.1 - 0.0035 16.7 17.0 0.0035 16.7 17.0 3.1 3 0 0 3 3 3 2 NOA36 protein DUF913 PF06025.12 EMR67968.1 - 0.015 14.3 1.2 0.015 14.3 1.2 2.9 2 1 0 3 3 3 0 Domain of Unknown Function (DUF913) PRTP PF01366.18 EMR67968.1 - 0.029 12.4 1.1 0.059 11.4 1.1 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Vfa1 PF08432.10 EMR67968.1 - 0.37 11.1 22.6 4 7.7 9.7 3.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.14 EMR67968.1 - 1.3 8.8 34.9 0.73 9.6 1.7 3.3 3 0 0 3 3 3 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 EMR67968.1 - 1.4 9.7 44.0 0.41 11.4 4.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) RNA_pol_3_Rpc31 PF11705.8 EMR67968.1 - 3.2 8.0 42.8 1.3 9.2 21.6 3.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Fungal_trans_2 PF11951.8 EMR67969.1 - 1.1e-08 34.3 0.2 0.0033 16.3 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Amino_oxidase PF01593.24 EMR67970.1 - 1.4e-51 176.2 0.0 1.9e-51 175.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR67970.1 - 1.3e-11 44.6 0.2 3e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR67970.1 - 0.0002 20.6 0.2 0.0004 19.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR67970.1 - 0.00036 20.2 0.3 0.0018 17.9 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMR67970.1 - 0.0011 18.2 0.3 0.0019 17.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR67970.1 - 0.0016 17.7 0.0 0.0034 16.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR67970.1 - 0.0017 17.1 0.1 0.0028 16.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EMR67970.1 - 0.008 15.6 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EMR67970.1 - 0.0096 14.8 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 EMR67970.1 - 0.098 12.6 0.4 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMR67970.1 - 0.16 12.6 0.1 0.37 11.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR67970.1 - 0.39 9.5 1.6 0.5 9.1 0.1 1.9 3 0 0 3 3 3 0 Tryptophan halogenase Peptidase_C97 PF05903.14 EMR67971.1 - 3.7e-35 121.0 0.0 4.6e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EMR67971.1 - 0.0097 16.2 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.12 EMR67971.1 - 0.1 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Pyr_redox_3 PF13738.6 EMR67972.1 - 1.6e-10 40.7 0.9 1.6e-06 27.6 0.0 3.9 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMR67972.1 - 6.6e-10 38.0 0.9 3.7e-09 35.6 0.1 2.3 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMR67972.1 - 1.7e-09 37.4 0.1 5.3e-06 25.9 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR67972.1 - 1.1e-07 31.3 4.0 1.5e-06 27.6 0.1 2.8 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EMR67972.1 - 8.3e-05 22.3 1.2 0.2 11.2 0.3 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EMR67972.1 - 0.12 11.5 0.1 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EMR67972.1 - 0.32 11.0 1.4 1.6 8.7 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Nitroreductase PF00881.24 EMR67974.1 - 1.6e-26 93.4 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EMR67974.1 - 8.9e-09 35.2 0.1 0.051 13.1 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase YukD PF08817.10 EMR67974.1 - 0.18 12.5 0.5 0.66 10.7 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Ribosomal_S11 PF00411.19 EMR67975.1 - 1.5e-10 41.4 0.0 2.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Phage_Mu_Gam PF07352.12 EMR67975.1 - 0.019 14.8 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein rOmpB PF12334.8 EMR67975.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Tim44 PF04280.15 EMR67976.1 - 1.6e-36 125.6 0.0 8.7e-36 123.2 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain DUF445 PF04286.12 EMR67976.1 - 0.17 11.7 2.3 0.39 10.5 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Med7 PF05983.11 EMR67976.1 - 6.5 6.8 9.6 1.4 9.0 6.1 1.6 2 0 0 2 2 2 0 MED7 protein adh_short PF00106.25 EMR67977.1 - 2.7e-33 115.1 0.0 1.1e-32 113.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR67977.1 - 6.6e-25 88.0 0.0 9.7e-24 84.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RPEL PF02755.15 EMR67977.1 - 0.037 13.7 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 RPEL repeat Methyltransf_25 PF13649.6 EMR67977.1 - 0.16 12.7 0.0 0.33 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EMR67977.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_47 PF01532.20 EMR67978.1 - 4.5e-67 226.9 0.0 5.1e-59 200.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 AAA_11 PF13086.6 EMR67979.1 - 7.2e-58 196.4 0.7 2.5e-57 194.6 0.3 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EMR67979.1 - 4e-56 189.8 0.0 1.2e-55 188.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMR67979.1 - 3.3e-11 43.3 0.0 8.2e-10 38.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR67979.1 - 7.5e-09 36.1 0.0 5e-08 33.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EMR67979.1 - 6.5e-08 32.6 0.0 0.22 11.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EMR67979.1 - 1.9e-06 27.4 0.2 7.8e-06 25.4 0.2 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EMR67979.1 - 3.5e-06 27.1 0.0 2.2e-05 24.5 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EMR67979.1 - 8.8e-06 25.4 0.1 1.9e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EMR67979.1 - 5.8e-05 23.4 0.1 0.0016 18.7 0.2 2.8 2 1 0 2 2 1 1 AAA domain T2SSE PF00437.20 EMR67979.1 - 0.0004 19.5 0.0 0.0008 18.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 EMR67979.1 - 0.00048 20.0 0.0 0.015 15.1 0.0 2.4 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.6 EMR67979.1 - 0.00081 19.8 0.1 0.0028 18.1 0.1 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.6 EMR67979.1 - 0.002 17.7 0.2 0.83 9.2 0.0 3.4 3 1 0 4 4 4 1 AAA domain UvrD_C PF13361.6 EMR67979.1 - 0.0041 16.5 0.1 2.5 7.4 0.0 3.1 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.14 EMR67979.1 - 0.0072 16.3 0.3 0.031 14.3 0.0 2.2 2 1 1 3 3 2 1 Flavivirus DEAD domain PhoH PF02562.16 EMR67979.1 - 0.0076 15.7 0.0 0.09 12.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 EMR67979.1 - 0.0082 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 EMR67979.1 - 0.011 16.1 0.1 0.13 12.7 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EMR67979.1 - 0.013 15.4 0.5 5.8 6.8 0.0 3.3 3 0 0 3 3 3 0 NTPase 4HB_MCP_1 PF12729.7 EMR67979.1 - 0.019 14.5 0.2 0.047 13.2 0.2 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_24 PF13479.6 EMR67979.1 - 0.025 14.3 0.1 0.18 11.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 EMR67979.1 - 0.039 13.8 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PucR PF07905.11 EMR67979.1 - 0.048 13.9 0.0 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family ABC_tran PF00005.27 EMR67979.1 - 0.06 13.9 0.0 0.21 12.1 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EMR67979.1 - 0.06 13.3 0.1 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 EMR67979.1 - 0.09 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 EMR67979.1 - 0.15 12.5 1.0 2.9 8.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain NLRC4_HD2 PF17776.1 EMR67979.1 - 0.16 12.5 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 NLRC4 helical domain HD2 CpcD PF01383.21 EMR67979.1 - 0.17 12.2 0.2 0.48 10.7 0.2 1.7 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain Ribosomal_L30_N PF08079.12 EMR67979.1 - 0.38 11.0 4.3 1 9.7 4.3 1.7 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain HTH_32 PF13565.6 EMR67980.1 - 0.0036 17.9 0.1 0.006 17.2 0.0 1.4 1 1 1 2 2 2 1 Homeodomain-like domain Med13_C PF06333.12 EMR67982.1 - 3e-58 197.6 2.9 5.7e-58 196.8 2.9 1.4 1 1 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain PNP_UDP_1 PF01048.20 EMR67983.1 - 1.1e-24 87.0 0.1 1.4e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily FAT PF02259.23 EMR67986.1 - 1.7e-131 438.6 1.4 3.6e-131 437.5 1.4 1.6 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 EMR67986.1 - 1.2e-79 265.9 0.9 5.4e-73 244.2 0.0 5.4 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 EMR67986.1 - 2e-73 247.3 0.0 4e-73 246.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EMR67986.1 - 2.8e-45 152.7 1.9 1.9e-44 150.1 0.1 3.5 4 0 0 4 4 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EMR67986.1 - 2.5e-13 50.2 7.2 0.0076 16.6 0.0 7.9 8 0 0 8 8 7 2 HEAT repeats FATC PF02260.20 EMR67986.1 - 7.4e-13 48.1 0.2 2e-12 46.7 0.2 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EMR67986.1 - 2.6e-11 42.7 19.0 0.0068 16.6 0.0 11.3 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.6 EMR67986.1 - 3.5e-10 40.2 17.3 0.001 19.5 0.0 11.6 11 2 2 13 13 12 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EMR67986.1 - 4e-06 27.3 0.2 24 5.6 0.0 7.0 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EMR67986.1 - 7.5e-06 24.8 5.1 0.025 13.1 0.2 4.4 4 1 0 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.7 EMR67986.1 - 5.7e-05 23.2 4.0 0.3 11.1 0.0 5.3 5 1 1 6 6 5 2 non-SMC mitotic condensation complex subunit 1 VirDNA-topo-I_N PF09266.10 EMR67986.1 - 0.0056 16.8 0.1 0.015 15.4 0.1 1.7 1 0 0 1 1 1 1 Viral DNA topoisomerase I, N-terminal CLASP_N PF12348.8 EMR67986.1 - 0.013 15.1 10.3 13 5.2 0.0 6.8 6 2 1 8 8 8 0 CLASP N terminal Sec7_N PF12783.7 EMR67986.1 - 0.023 14.6 2.9 8.1 6.3 0.0 4.4 4 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ANAPC3 PF12895.7 EMR67986.1 - 0.025 14.8 5.0 12 6.2 0.0 4.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 IFRD PF05004.13 EMR67986.1 - 0.025 13.7 0.1 5.5 6.0 0.0 3.7 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) RICTOR_N PF14664.6 EMR67986.1 - 0.21 10.5 1.2 2.3 7.1 0.1 2.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term FANCI_S2 PF14676.6 EMR67986.1 - 0.43 10.9 4.6 6.9 6.9 0.0 4.5 6 0 0 6 6 4 0 FANCI solenoid 2 F-box PF00646.33 EMR67987.1 - 2.1e-05 24.3 0.1 4e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMR67987.1 - 8e-05 22.5 0.2 0.00017 21.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 EMR67988.1 - 1.8e-24 86.3 39.9 3.7e-19 68.8 9.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR67988.1 - 1.8e-07 30.4 0.2 1.8e-07 30.4 0.2 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EMR67988.1 - 0.042 12.7 9.1 0.06 12.2 0.1 2.5 2 0 0 2 2 2 0 MFS_1 like family NUC153 PF08159.12 EMR67990.1 - 8.6e-12 44.7 2.4 1.9e-11 43.6 2.4 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EMR67990.1 - 1.7e-07 31.8 0.0 0.0019 19.0 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR67990.1 - 0.055 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_71 PF03659.14 EMR67991.1 - 6.1e-116 387.3 5.3 7.6e-116 387.0 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Iron_transport PF10634.9 EMR67992.1 - 0.13 12.4 0.1 0.62 10.2 0.0 2.1 3 0 0 3 3 3 0 Fe2+ transport protein PRKCSH-like PF12999.7 EMR67993.1 - 1.1e-38 132.8 8.6 2.7e-23 82.7 1.1 3.3 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EMR67993.1 - 2.9e-31 108.2 0.6 2.9e-31 108.2 0.6 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EMR67993.1 - 1.3e-11 45.3 0.5 3.9e-11 43.8 0.5 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 EMR67993.1 - 0.0033 17.6 1.6 0.0033 17.6 1.6 2.5 2 1 0 2 2 1 1 Low-density lipoprotein receptor domain class A DUF4200 PF13863.6 EMR67993.1 - 0.0048 17.3 9.7 0.0048 17.3 9.7 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) ATG27 PF09451.10 EMR67993.1 - 0.018 14.9 1.2 0.018 14.9 1.2 1.8 2 0 0 2 2 2 0 Autophagy-related protein 27 DUF5082 PF16888.5 EMR67993.1 - 0.019 15.2 6.4 0.037 14.3 0.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) TolA PF06519.11 EMR67993.1 - 0.026 14.7 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 TolA C-terminal GLE1 PF07817.13 EMR67993.1 - 0.059 12.6 0.4 0.11 11.6 0.3 1.5 1 1 0 1 1 1 0 GLE1-like protein DUF3435 PF11917.8 EMR67993.1 - 0.12 11.2 5.7 4.1 6.2 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) YvrJ PF12841.7 EMR67993.1 - 0.17 11.5 0.7 0.38 10.3 0.7 1.6 1 0 0 1 1 1 0 YvrJ protein family DUF3584 PF12128.8 EMR67993.1 - 0.28 8.7 14.4 0.02 12.4 9.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.20 EMR67993.1 - 1.2 9.1 17.2 0.057 13.4 3.5 3.6 4 0 0 4 4 3 0 Prefoldin subunit UPF0242 PF06785.11 EMR67993.1 - 1.8 8.7 8.2 0.66 10.0 4.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rab5-bind PF09311.11 EMR67993.1 - 1.8 7.9 10.1 1.4 8.3 7.6 2.0 2 1 0 2 2 2 0 Rabaptin-like protein ABC_tran_CTD PF16326.5 EMR67993.1 - 2 8.7 11.7 0.092 13.0 1.1 3.1 3 1 0 3 3 3 0 ABC transporter C-terminal domain Osmo_CC PF08946.10 EMR67993.1 - 3.1 8.1 5.1 1.3 9.3 1.6 2.2 1 1 1 2 2 2 0 Osmosensory transporter coiled coil DivIC PF04977.15 EMR67993.1 - 3.1 7.6 12.6 0.17 11.7 3.6 3.1 3 0 0 3 3 3 0 Septum formation initiator Mod_r PF07200.13 EMR67993.1 - 4 7.5 12.7 28 4.8 9.6 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fzo_mitofusin PF04799.13 EMR67993.1 - 5.3 6.6 5.9 5.3 6.6 3.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region HAUS6_N PF14661.6 EMR67993.1 - 5.9 6.4 10.3 23 4.5 5.7 2.4 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.14 EMR67993.1 - 7.2 7.0 16.2 32 4.8 0.3 3.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) PspA_IM30 PF04012.12 EMR67993.1 - 7.3 6.1 16.9 0.5 9.9 10.9 2.2 2 1 0 2 2 2 0 PspA/IM30 family Rtf2 PF04641.12 EMR67994.1 - 1.5e-47 162.2 3.5 1.9e-47 161.9 3.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.6 EMR67994.1 - 0.0043 17.0 0.2 0.052 13.6 0.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 EMR67994.1 - 0.015 15.1 0.1 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 EMR67994.1 - 0.036 14.4 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 EMR67994.1 - 0.046 13.7 0.1 0.32 11.0 0.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMR67994.1 - 0.068 13.0 0.7 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMR67994.1 - 0.11 12.3 0.7 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 RING-like zinc finger UPF0547 PF10571.9 EMR67994.1 - 1.8 8.7 4.0 38 4.5 1.9 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 BRF1 PF07741.13 EMR67994.1 - 3.6 8.0 9.1 2.8 8.3 7.0 1.9 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Ank_2 PF12796.7 EMR67995.1 - 1.9e-61 204.6 22.8 2.4e-15 56.9 0.0 6.3 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR67995.1 - 5.4e-45 151.2 19.5 1.1e-09 38.6 0.0 9.6 3 3 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR67995.1 - 1.7e-41 135.4 11.8 0.00079 19.7 0.0 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 EMR67995.1 - 4.9e-37 125.5 17.5 4.9e-07 29.9 0.2 8.4 5 1 3 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EMR67995.1 - 1e-33 114.3 28.5 0.00018 21.8 0.4 12.4 12 1 0 12 12 12 8 Ankyrin repeat RhgB_N PF09284.10 EMR67996.1 - 4.6e-106 354.0 6.4 8.4e-106 353.1 6.4 1.4 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EMR67996.1 - 2.2e-42 144.7 0.5 1.2e-41 142.3 0.0 2.4 2 1 1 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EMR67996.1 - 3.2e-21 74.9 9.6 3.2e-21 74.9 9.6 3.1 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EMR67996.1 - 4e-05 23.8 5.4 4e-05 23.8 5.4 3.2 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain Kelch_6 PF13964.6 EMR67996.1 - 0.061 13.6 1.2 0.6 10.5 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 EMR67996.1 - 0.1 12.6 0.1 7.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Kelch motif DUF1735 PF08522.10 EMR67996.1 - 6.4 7.4 8.7 3.9 8.1 0.4 4.1 3 2 0 3 3 3 0 Domain of unknown function (DUF1735) MBOAT_2 PF13813.6 EMR67997.1 - 1.7e-08 34.6 1.1 3.8e-08 33.5 1.1 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PepX_C PF08530.10 EMR67997.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Pex24p PF06398.11 EMR67998.1 - 1.8e-90 303.6 0.0 2.2e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin GCIP PF13324.6 EMR67999.1 - 6.5e-23 81.7 0.1 4.6e-22 78.9 0.0 2.3 1 1 1 2 2 2 1 Grap2 and cyclin-D-interacting KptA_kDCL PF18176.1 EMR67999.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain Mis14 PF08641.12 EMR67999.1 - 0.19 12.1 2.2 0.43 10.9 2.2 1.6 1 0 0 1 1 1 0 Kinetochore protein Mis14 like CdvA PF18822.1 EMR67999.1 - 0.2 11.5 3.9 0.96 9.3 0.0 2.9 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Pes-10 PF07149.11 EMR67999.1 - 1.9 7.5 5.5 2.8 6.9 5.5 1.2 1 0 0 1 1 1 0 Pes-10 RRN3 PF05327.11 EMR67999.1 - 2.1 6.8 4.9 3.5 6.1 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA PF00004.29 EMR68000.1 - 0.076 13.4 0.1 0.093 13.2 0.1 1.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.7 EMR68002.1 - 8.9e-23 80.7 0.0 1.4e-10 41.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR68002.1 - 2.3e-18 66.0 2.2 1.1e-07 31.9 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR68002.1 - 4.8e-17 62.1 0.3 4.7e-12 46.2 0.1 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EMR68002.1 - 1.1e-16 60.4 0.3 0.0015 18.9 0.1 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EMR68002.1 - 3e-15 54.8 0.1 0.0029 18.0 0.0 5.5 5 0 0 5 5 4 3 Ankyrin repeat NACHT PF05729.12 EMR68002.1 - 8.4e-11 42.1 0.0 2.9e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain PNP_UDP_1 PF01048.20 EMR68002.1 - 2e-05 24.0 0.8 9.1e-05 21.8 0.1 2.3 2 0 0 2 2 2 1 Phosphorylase superfamily KAP_NTPase PF07693.14 EMR68002.1 - 9.5e-05 21.8 0.0 0.00044 19.6 0.0 1.9 2 0 0 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.6 EMR68002.1 - 0.004 17.6 0.0 0.022 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMR68002.1 - 0.037 14.3 0.1 0.38 11.0 0.0 2.7 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EMR68002.1 - 0.17 11.9 0.0 35 4.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HTH_45 PF14947.6 EMR68006.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix Baculo_helicase PF04735.12 EMR68006.1 - 0.28 8.7 0.0 0.36 8.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase Sds3 PF08598.11 EMR68008.1 - 1.9e-20 73.8 6.4 3.3e-20 73.0 6.3 1.7 1 1 0 1 1 1 1 Sds3-like UQ_con PF00179.26 EMR68009.1 - 3.1e-08 33.4 0.0 8.5e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMR68009.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B COG5 PF10392.9 EMR68011.1 - 0.49 10.6 4.5 0.45 10.7 0.7 2.8 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Peptidase_M24 PF00557.24 EMR68012.1 - 1.4e-59 201.3 0.0 3.6e-59 200.0 0.0 1.6 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EMR68012.1 - 1.8e-06 27.7 0.0 4.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SH3_1 PF00018.28 EMR68013.1 - 5.1e-14 51.6 0.1 8e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMR68013.1 - 2.2e-12 46.6 0.1 3.4e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMR68013.1 - 1.6e-07 30.9 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF910 PF06014.11 EMR68013.1 - 0.2 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) Ribosomal_L14e PF01929.17 EMR68014.1 - 2.9e-30 104.6 3.1 3.9e-30 104.2 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EMR68014.1 - 0.024 14.6 0.4 0.044 13.7 0.0 1.6 2 0 0 2 2 2 0 KOW motif Prot_ATP_ID_OB PF16450.5 EMR68014.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain GMC_oxred_N PF00732.19 EMR68015.1 - 1.7e-64 218.1 0.0 2.1e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR68015.1 - 3.2e-32 112.0 0.0 5.6e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR68015.1 - 7.2e-07 28.6 0.1 4.3e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR68015.1 - 1.1e-05 25.2 0.5 4.4e-05 23.2 0.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR68015.1 - 8.8e-05 21.7 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMR68015.1 - 0.00025 21.2 0.1 0.00061 20.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR68015.1 - 0.00058 19.2 0.0 0.28 10.4 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR68015.1 - 0.0011 18.3 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR68015.1 - 0.0084 15.4 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EMR68015.1 - 0.057 12.1 0.1 0.11 11.2 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Peptidase_A4 PF01828.17 EMR68016.1 - 5.9e-31 107.6 0.1 7.1e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family YIF1 PF03878.15 EMR68017.1 - 1.6e-100 335.6 0.8 1.9e-100 335.3 0.8 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EMR68017.1 - 0.39 10.4 11.9 0.13 12.0 8.8 1.7 1 1 1 2 2 2 0 Yip1 domain zf-MYND PF01753.18 EMR68018.1 - 0.0023 18.0 3.8 0.0062 16.6 3.8 1.7 1 1 0 1 1 1 1 MYND finger Radial_spoke PF04712.12 EMR68019.1 - 0.1 11.5 0.8 0.16 10.9 0.8 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein NAC PF01849.18 EMR68020.1 - 1.6e-23 82.5 0.1 3.1e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 NAC domain PGA2 PF07543.12 EMR68020.1 - 3.5 7.6 11.5 9.4 6.2 0.5 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 CENP-B_dimeris PF09026.10 EMR68020.1 - 4.5 7.7 15.3 9.4 6.7 8.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Goodbye PF17109.5 EMR68021.1 - 5.5e-28 97.9 0.0 4e-27 95.1 0.0 2.7 2 0 0 2 2 1 1 fungal STAND N-terminal Goodbye domain TPR_12 PF13424.6 EMR68021.1 - 6.3e-08 32.8 0.1 9.9e-05 22.6 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR68021.1 - 7.8e-07 28.7 3.4 0.043 13.9 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMR68021.1 - 5.5e-06 26.0 1.0 0.49 10.1 0.2 4.5 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 EMR68021.1 - 0.00033 21.1 0.7 0.054 14.0 0.0 4.0 4 1 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMR68021.1 - 0.00053 20.0 9.1 0.35 11.2 0.1 5.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR68021.1 - 0.0021 17.8 0.8 0.045 13.6 0.1 3.5 4 0 0 4 4 2 1 Tetratricopeptide repeat NACHT PF05729.12 EMR68021.1 - 0.0068 16.3 0.1 0.096 12.6 0.1 2.8 2 1 0 2 2 2 1 NACHT domain TPR_14 PF13428.6 EMR68021.1 - 0.0071 17.1 0.4 18 6.5 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.6 EMR68021.1 - 0.064 13.5 0.0 0.63 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain ANAPC5 PF12862.7 EMR68021.1 - 0.072 13.2 0.0 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF4890 PF16231.5 EMR68021.1 - 0.1 13.1 1.8 0.52 10.8 1.8 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) DUF2267 PF10025.9 EMR68021.1 - 0.12 12.7 0.0 5.1 7.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) AAA_16 PF13191.6 EMR68021.1 - 0.12 12.7 0.0 0.65 10.4 0.0 2.3 2 0 0 2 2 1 0 AAA ATPase domain TPR_6 PF13174.6 EMR68021.1 - 0.53 11.0 4.0 13 6.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat THOC7 PF05615.13 EMR68021.1 - 3.9 7.8 10.2 0.51 10.6 4.0 2.7 2 0 0 2 2 2 0 Tho complex subunit 7 PKK PF12474.8 EMR68022.1 - 0.017 15.3 11.0 0.017 15.3 11.0 4.2 2 2 2 4 4 4 0 Polo kinase kinase Choline_kinase PF01633.20 EMR68022.1 - 0.18 11.3 8.2 0.13 11.8 1.4 2.1 1 1 0 2 2 2 0 Choline/ethanolamine kinase Mt_ATP-synt_D PF05873.12 EMR68023.1 - 1.1e-21 77.2 0.9 1.5e-21 76.9 0.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) GIDA_assoc PF13932.6 EMR68023.1 - 0.066 13.4 1.2 0.084 13.0 1.2 1.1 1 0 0 1 1 1 0 GidA associated domain T5orf172 PF10544.9 EMR68023.1 - 0.075 13.6 0.1 0.21 12.1 0.0 1.7 1 1 1 2 2 2 0 T5orf172 domain Med18 PF09637.10 EMR68023.1 - 0.084 12.7 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Med18 protein Peptidase_S8 PF00082.22 EMR68024.1 - 2e-55 188.2 0.1 2.9e-55 187.6 0.1 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EMR68024.1 - 2.4e-08 34.7 0.1 4.7e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Fn3-like domain Aldo_ket_red PF00248.21 EMR68025.1 - 3.6e-42 144.6 0.0 4e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_fiss_reg PF05308.11 EMR68026.1 - 0.82 9.7 7.7 2.3 8.2 0.2 3.1 3 0 0 3 3 3 0 Mitochondrial fission regulator Herpes_UL32 PF06070.11 EMR68026.1 - 2.3 5.9 9.8 3.7 5.2 9.8 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Mpv17_PMP22 PF04117.12 EMR68027.1 - 2.4e-10 40.5 4.5 7e-10 39.0 0.5 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Sulfotransfer_4 PF17784.1 EMR68028.1 - 2e-15 57.2 0.1 2.3e-15 57.0 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR68028.1 - 0.0058 17.0 0.0 0.0067 16.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family F-box-like PF12937.7 EMR68030.1 - 1.2e-07 31.5 0.1 4.5e-07 29.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 EMR68030.1 - 0.13 12.3 0.5 0.79 9.9 0.3 2.6 2 0 0 2 2 2 0 Leucine Rich repeat F-box PF00646.33 EMR68030.1 - 0.15 12.0 0.9 0.61 10.0 0.1 2.4 3 0 0 3 3 3 0 F-box domain MFS_1 PF07690.16 EMR68031.1 - 1.8e-22 79.8 34.3 1.8e-22 79.8 34.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR68031.1 - 2.4e-06 26.7 27.4 7.4e-06 25.1 27.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EMR68031.1 - 0.00066 18.2 5.1 0.0012 17.3 5.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short_C2 PF13561.6 EMR68032.1 - 3.3e-06 26.8 0.0 6.2e-06 25.9 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR68032.1 - 1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase SRP-alpha_N PF04086.13 EMR68033.1 - 3.8e-85 286.4 0.0 7.1e-85 285.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EMR68033.1 - 1.1e-46 158.9 0.2 3.5e-45 154.1 0.2 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EMR68033.1 - 3.2e-08 33.7 0.4 8.5e-08 32.3 0.1 1.8 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EMR68033.1 - 2.7e-07 29.8 0.1 5.1e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EMR68033.1 - 7.7e-05 22.5 0.1 0.00016 21.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMR68033.1 - 0.0016 18.9 0.5 0.0039 17.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMR68033.1 - 0.0083 15.7 0.1 0.03 13.9 0.1 1.9 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMR68033.1 - 0.0096 16.0 0.4 0.051 13.7 0.4 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 EMR68033.1 - 0.013 15.5 0.0 0.24 11.5 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EMR68033.1 - 0.015 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR68033.1 - 0.02 15.3 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EMR68033.1 - 0.048 14.2 0.1 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_31 PF13614.6 EMR68033.1 - 0.052 13.5 0.1 0.59 10.0 0.0 2.3 1 1 0 2 2 2 0 AAA domain MmgE_PrpD PF03972.14 EMR68034.1 - 5.8e-144 479.9 0.0 6.6e-144 479.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family KNOX2 PF03791.13 EMR68034.1 - 0.095 12.2 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 KNOX2 domain KORA PF16509.5 EMR68034.1 - 0.17 12.2 0.1 0.43 10.9 0.1 1.6 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor RRM_1 PF00076.22 EMR68036.1 - 7.5e-11 41.7 0.4 0.00027 20.7 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 EMR68036.1 - 1.7e-07 31.0 3.5 4.8e-07 29.6 3.5 1.7 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 EMR68036.1 - 3e-05 23.2 4.7 5.9e-05 22.3 4.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 EMR68036.1 - 3.8e-05 23.7 1.7 3.8e-05 23.7 1.7 2.3 2 0 0 2 2 2 1 G-patch domain RED_N PF07808.13 EMR68036.1 - 0.0068 16.0 0.1 0.0068 16.0 0.1 2.9 4 0 0 4 4 4 1 RED-like protein N-terminal region zf-C2H2_jaz PF12171.8 EMR68036.1 - 0.1 12.9 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMR68036.1 - 1.7 9.1 4.8 0.24 11.8 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EMR68036.1 - 4.2 7.2 8.7 0.16 11.8 2.3 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type F-box PF00646.33 EMR68037.1 - 7.3e-05 22.5 0.4 0.00016 21.5 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMR68037.1 - 0.00011 22.0 0.2 0.00026 20.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like adh_short PF00106.25 EMR68039.1 - 3.3e-35 121.3 0.4 8.1e-35 120.1 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68039.1 - 1.3e-21 77.2 0.4 2.3e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR68039.1 - 0.00029 20.4 0.0 0.023 14.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family CPSF100_C PF13299.6 EMR68040.1 - 4.2e-52 176.8 0.1 5.3e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 EMR68040.1 - 6.6e-15 54.8 0.0 1.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain DASH_Spc19 PF08287.11 EMR68041.1 - 3.6e-48 163.4 0.0 5.9e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Spc19 MiAMP1 PF09117.10 EMR68042.1 - 0.071 13.3 1.2 0.16 12.2 1.2 1.6 1 1 0 1 1 1 0 MiAMP1 GMC_oxred_C PF05199.13 EMR68043.1 - 1e-31 110.4 0.1 1.4e-31 110.0 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR68043.1 - 7.5e-20 71.5 0.1 1e-19 71.0 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase DNase_NucA_NucB PF14040.6 EMR68044.1 - 3.9e-14 53.0 7.1 2.9e-06 27.6 3.3 2.4 1 1 1 2 2 2 2 Deoxyribonuclease NucA/NucB SH3_1 PF00018.28 EMR68045.1 - 5e-09 35.6 0.0 9.8e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMR68045.1 - 1.5e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMR68045.1 - 2e-06 27.4 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3112 PF11309.8 EMR68045.1 - 0.54 9.7 5.3 0.92 8.9 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) MFS_1 PF07690.16 EMR68047.1 - 1.9e-27 96.1 24.0 1.9e-27 96.1 24.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Dynactin_p22 PF07426.11 EMR68049.1 - 3.6e-06 27.0 0.0 4.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Cu_amine_oxid PF01179.20 EMR68050.1 - 1e-129 433.1 7.5 1.3e-129 432.7 7.5 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EMR68050.1 - 3.1e-34 116.6 0.8 8.3e-34 115.2 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EMR68050.1 - 5.7e-05 23.3 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu-oxidase_2 PF07731.14 EMR68050.1 - 0.074 12.8 1.0 0.2 11.4 0.6 1.9 1 1 0 1 1 1 0 Multicopper oxidase UCR_14kD PF02271.16 EMR68052.1 - 6.5e-46 154.4 0.1 7.6e-46 154.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit NIF PF03031.18 EMR68052.1 - 0.076 12.8 0.1 0.41 10.4 0.0 1.9 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase Anp1 PF03452.14 EMR68053.1 - 1.8e-100 335.7 0.0 2.2e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Anp1 HhH-GPD PF00730.25 EMR68054.1 - 7.2e-13 48.9 0.0 6.4e-12 45.9 0.0 2.2 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Mito_carr PF00153.27 EMR68055.1 - 5.8e-31 106.3 0.5 1e-19 70.2 0.6 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein LRR_6 PF13516.6 EMR68057.1 - 5.4e-05 22.9 3.9 0.99 9.6 0.0 5.7 5 0 0 5 5 5 3 Leucine Rich repeat adh_short PF00106.25 EMR68058.1 - 3.9e-20 72.2 0.0 2.8e-19 69.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68058.1 - 3.2e-14 53.1 0.0 7.6e-14 51.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68058.1 - 0.00014 21.8 0.1 0.00022 21.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR68058.1 - 0.0014 18.1 0.1 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3657 PF12394.8 EMR68058.1 - 0.15 12.7 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein FAM135 Arm PF00514.23 EMR68060.1 - 4.4e-98 318.7 16.4 3.7e-14 52.2 0.2 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EMR68060.1 - 3.7e-27 94.6 2.1 3.7e-27 94.6 2.1 1.9 2 0 0 2 2 1 1 Importin beta binding domain HEAT_EZ PF13513.6 EMR68060.1 - 2.6e-25 88.5 5.5 1.2e-09 38.4 0.1 6.5 6 0 0 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 EMR68060.1 - 6.1e-24 83.3 3.0 9.8e-24 82.7 2.0 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 EMR68060.1 - 2e-20 73.0 0.1 5e-09 36.4 0.0 5.3 1 1 3 5 5 5 4 HEAT repeats HEAT PF02985.22 EMR68060.1 - 1.4e-19 68.5 3.7 3.5e-06 26.8 0.0 7.5 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 EMR68060.1 - 7.6e-08 32.1 0.0 0.046 13.2 0.0 3.9 3 1 2 5 5 5 3 Armadillo-like Adaptin_N PF01602.20 EMR68060.1 - 5.2e-06 25.3 0.0 0.00075 18.2 0.0 2.8 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 EMR68060.1 - 0.0001 22.4 0.0 1.7 8.8 0.0 4.5 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 EMR68060.1 - 0.0011 19.5 0.3 2.2 9.2 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 EMR68060.1 - 0.0015 18.6 0.0 2.6 8.1 0.0 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 EMR68060.1 - 0.012 15.9 4.6 1.2 9.4 0.0 4.6 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 EMR68060.1 - 0.02 14.5 0.0 9 5.8 0.0 3.8 1 1 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Glycos_trans_3N PF02885.17 EMR68060.1 - 0.13 12.1 0.0 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain zf-C2HE PF16278.5 EMR68061.1 - 1.1e-17 64.2 0.2 3.3e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EMR68061.1 - 3.3e-15 56.5 0.1 2e-06 28.2 0.3 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EMR68061.1 - 6.7e-12 46.0 0.9 1.3e-10 41.9 0.9 2.2 1 1 0 1 1 1 1 HIT domain Roughex PF06020.11 EMR68061.1 - 0.97 8.5 5.4 1.4 7.9 5.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Paf1 PF03985.13 EMR68061.1 - 2.1 7.3 7.3 2.9 6.8 7.3 1.1 1 0 0 1 1 1 0 Paf1 Cyclin_N PF00134.23 EMR68062.1 - 8.8e-42 141.8 0.0 1.4e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMR68062.1 - 8.3e-36 122.7 0.1 2.9e-34 117.7 0.0 2.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Zn_clus PF00172.18 EMR68063.1 - 0.0003 20.8 12.3 0.00056 20.0 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EMR68064.1 - 1.5e-34 119.5 30.2 1.8e-34 119.2 30.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AT_hook PF02178.19 EMR68065.1 - 0.025 14.4 4.3 0.025 14.4 4.3 6.1 5 0 0 5 5 5 0 AT hook motif CDC27 PF09507.10 EMR68065.1 - 0.063 12.7 14.3 0.073 12.4 14.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 EMR68065.1 - 0.14 12.1 9.0 0.17 11.8 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SWIRM-assoc_2 PF16496.5 EMR68065.1 - 0.72 8.7 4.4 0.81 8.5 4.4 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Astro_capsid_p PF12226.8 EMR68065.1 - 0.95 8.6 8.0 1.3 8.1 8.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HA2 PF04408.23 EMR68066.1 - 4.7e-15 55.8 0.8 2.6e-14 53.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EMR68066.1 - 3e-14 53.2 0.0 5.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EMR68066.1 - 4.6e-13 49.5 0.0 9.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMR68066.1 - 4.9e-11 42.7 0.1 1.3e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 EMR68066.1 - 4.6e-07 30.1 0.0 1.1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 RWD domain ResIII PF04851.15 EMR68066.1 - 0.00022 21.3 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMR68066.1 - 0.0016 18.7 0.5 0.0075 16.5 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMR68066.1 - 0.0062 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EMR68066.1 - 0.017 14.8 0.1 0.3 10.8 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase PF06745.13 EMR68066.1 - 0.019 14.3 0.3 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 EMR68066.1 - 0.057 12.5 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EMR68066.1 - 0.089 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EMR68066.1 - 0.11 12.0 0.1 0.44 10.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EMR68066.1 - 0.18 12.4 0.1 0.61 10.6 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_23 PF13476.6 EMR68066.1 - 0.29 11.6 1.6 0.71 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain POT1PC PF16686.5 EMR68067.1 - 9.1e-50 168.5 0.5 2e-49 167.4 0.5 1.6 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EMR68067.1 - 3.7e-14 52.8 0.0 8.1e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Membralin PF09746.9 EMR68067.1 - 0.099 11.7 2.5 0.16 10.9 2.5 1.3 1 0 0 1 1 1 0 Tumour-associated protein CDC45 PF02724.14 EMR68067.1 - 7.1 4.8 12.4 13 3.9 12.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3824 PF12868.7 EMR68068.1 - 1.9e-15 57.8 41.0 1.2e-13 51.9 31.6 11.8 6 4 6 12 12 12 3 Domain of unknwon function (DUF3824) Phage_holin_3_3 PF16083.5 EMR68068.1 - 1.4 9.1 4.5 0.79 9.9 0.2 2.8 4 1 0 4 4 4 0 LydA holin phage, holin superfamily III FA_desaturase PF00487.24 EMR68068.1 - 6.9 6.4 11.6 25 4.6 0.2 3.4 2 1 1 3 3 3 0 Fatty acid desaturase DnaJ_C PF01556.18 EMR68069.1 - 3.4e-25 88.9 0.0 5.4e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMR68069.1 - 5.4e-25 87.3 1.9 7e-25 86.9 1.0 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMR68069.1 - 5.3e-14 52.3 15.3 8.7e-14 51.6 15.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EMR68069.1 - 0.00028 20.8 7.9 0.036 14.0 0.5 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EMR68069.1 - 0.00066 19.7 5.6 0.12 12.3 0.6 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 EMR68069.1 - 0.81 10.1 8.5 6.4 7.2 1.2 3.0 2 1 1 3 3 3 0 Restriction alleviation protein Lar TackOD1 PF18551.1 EMR68069.1 - 1.7 8.3 6.5 3.6 7.2 0.5 2.2 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 zf-FPG_IleRS PF06827.14 EMR68069.1 - 4.8 7.1 11.3 2.1 8.3 1.2 3.2 2 1 1 3 3 3 0 Zinc finger found in FPG and IleRS OB_NTP_bind PF07717.16 EMR68070.1 - 6.4e-22 77.7 0.1 1.4e-21 76.6 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EMR68070.1 - 1.1e-19 70.7 0.1 1.1e-19 70.7 0.1 3.4 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMR68070.1 - 2.7e-13 50.2 0.0 9e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMR68070.1 - 4.5e-06 26.5 0.0 9.8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMR68070.1 - 7.9e-06 26.2 0.0 3e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMR68070.1 - 0.00041 20.1 1.2 0.00064 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EMR68070.1 - 0.0011 18.1 0.0 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EMR68070.1 - 0.0051 17.1 0.1 0.017 15.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EMR68070.1 - 0.02 14.5 0.2 0.049 13.3 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EMR68070.1 - 0.061 13.8 0.0 0.25 11.9 0.0 2.1 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 EMR68070.1 - 0.067 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EMR68070.1 - 0.067 13.2 0.1 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EMR68070.1 - 0.21 12.1 0.1 0.21 12.1 0.1 3.2 1 1 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EMR68070.1 - 0.3 11.1 2.7 2.2 8.3 0.2 3.1 2 1 0 2 2 2 0 AAA domain Glyco_hydro_18 PF00704.28 EMR68071.1 - 5.1e-17 62.6 4.0 1e-16 61.6 4.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chorismate_bind PF00425.18 EMR68072.1 - 3.9e-88 295.3 0.0 2.1e-87 292.9 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EMR68072.1 - 8.6e-27 94.1 0.0 6.5e-20 71.8 0.0 4.0 4 1 0 4 4 4 3 Anthranilate synthase component I, N terminal region YebG PF07130.12 EMR68072.1 - 0.095 12.6 0.1 0.33 10.8 0.1 1.9 1 1 0 1 1 1 0 YebG protein HscB_4_cys PF18256.1 EMR68073.1 - 0.01 15.6 0.7 0.022 14.5 0.7 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zinc_ribbon_2 PF13240.6 EMR68073.1 - 0.011 15.4 0.2 0.011 15.4 0.2 1.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EMR68073.1 - 0.021 14.2 0.2 0.049 13.1 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 EMR68073.1 - 0.029 14.1 0.5 0.083 12.6 0.2 1.8 1 1 1 2 2 2 0 A2L zinc ribbon domain Yippee-Mis18 PF03226.14 EMR68073.1 - 0.032 14.4 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.14 EMR68073.1 - 0.034 14.5 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 EMR68073.1 - 0.059 13.5 0.7 0.1 12.8 0.7 1.3 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Auto_anti-p27 PF06677.12 EMR68073.1 - 0.17 12.0 0.6 0.28 11.4 0.6 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ARD PF03079.14 EMR68074.1 - 1.5e-41 142.2 0.1 1.8e-41 142.0 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EMR68074.1 - 2.4e-09 36.8 0.0 3.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EMR68074.1 - 1.1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain tRNA-synt_1c PF00749.21 EMR68075.1 - 6.8e-61 205.9 0.0 9.6e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HflK_N PF12221.8 EMR68075.1 - 0.11 12.6 0.5 2 8.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Peptidase_S24 PF00717.23 EMR68075.1 - 0.15 12.1 0.0 4.3 7.4 0.0 2.6 2 1 0 2 2 2 0 Peptidase S24-like tRNA-synt_1b PF00579.25 EMR68076.1 - 9.4e-56 189.3 0.0 1.1e-55 189.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF883 PF05957.13 EMR68076.1 - 0.11 13.2 1.3 0.23 12.1 0.6 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GIDA PF01134.22 EMR68077.1 - 9.9e-155 515.4 0.0 1.5e-154 514.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Sec1 PF00995.23 EMR68077.1 - 9.1e-120 401.6 1.0 4.3e-119 399.4 1.0 1.9 1 1 0 1 1 1 1 Sec1 family GIDA_assoc PF13932.6 EMR68077.1 - 3.7e-68 229.9 0.2 8.9e-68 228.6 0.2 1.7 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EMR68077.1 - 2.7e-05 23.7 2.8 5.1e-05 22.8 2.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR68077.1 - 5.3e-05 22.6 0.1 0.0001 21.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR68077.1 - 0.00093 18.4 2.5 0.003 16.7 2.6 1.8 2 0 0 2 2 2 1 FAD binding domain B12-binding PF02310.19 EMR68077.1 - 0.012 15.6 1.3 0.036 14.1 0.2 2.3 2 0 0 2 2 2 0 B12 binding domain AlaDh_PNT_C PF01262.21 EMR68077.1 - 0.021 14.1 0.1 0.05 12.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EMR68077.1 - 0.056 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EMR68077.1 - 0.067 11.9 1.3 0.36 9.5 0.5 2.1 2 0 0 2 2 2 0 HI0933-like protein Occludin_ELL PF07303.13 EMR68077.1 - 0.07 13.9 0.3 29 5.4 0.1 2.9 2 0 0 2 2 2 0 Occludin homology domain NAD_binding_7 PF13241.6 EMR68077.1 - 0.19 12.2 0.1 0.76 10.3 0.1 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding JAB PF01398.21 EMR68078.1 - 6.9e-31 106.7 0.4 1.4e-30 105.6 0.2 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EMR68078.1 - 1.2e-23 83.8 0.2 3.3e-23 82.4 0.2 1.8 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EMR68078.1 - 0.00017 21.3 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EMR68078.1 - 0.044 13.8 0.0 0.084 12.9 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) CPBP PF02517.16 EMR68079.1 - 3.6e-15 56.1 9.5 3.6e-15 56.1 9.5 3.0 3 1 1 4 4 4 1 CPBP intramembrane metalloprotease MBOAT PF03062.19 EMR68080.1 - 1.9e-55 188.7 8.8 1.9e-55 188.7 8.8 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.11 EMR68080.1 - 0.1 12.9 0.2 0.64 10.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) adh_short PF00106.25 EMR68081.1 - 4.3e-31 107.9 0.0 5.6e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68081.1 - 7.6e-22 78.0 0.0 9.2e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68081.1 - 2.8e-09 37.1 0.0 4.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR68081.1 - 1e-07 31.7 0.1 3.8e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMR68081.1 - 0.00058 19.1 0.0 0.00081 18.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EMR68081.1 - 0.0083 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMR68081.1 - 0.04 13.8 0.0 0.053 13.4 0.0 1.3 1 1 0 1 1 1 0 NAD(P)H-binding SDH_alpha PF03313.15 EMR68081.1 - 0.07 12.8 0.2 0.49 10.0 0.1 1.9 1 1 1 2 2 2 0 Serine dehydratase alpha chain NmrA PF05368.13 EMR68081.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EMR68081.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Creatinase_N_2 PF16189.5 EMR68082.1 - 1.3e-52 178.1 0.0 1e-51 175.3 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EMR68082.1 - 9.5e-42 143.0 0.0 1.3e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EMR68082.1 - 3.9e-23 81.3 0.1 1e-22 79.9 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EMR68082.1 - 4.9e-18 66.1 0.0 2.6e-16 60.5 0.0 2.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain MMM1 PF10296.9 EMR68083.1 - 8.5e-142 472.1 0.1 2.8e-140 467.1 0.1 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 EamA PF00892.20 EMR68084.1 - 0.00081 19.6 28.9 0.0021 18.3 9.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family Pyr_redox_2 PF07992.14 EMR68085.1 - 8.6e-37 127.0 0.4 8.2e-31 107.3 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR68085.1 - 1.1e-10 42.0 0.0 5.8e-10 39.6 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR68085.1 - 0.00014 21.3 0.0 0.0022 17.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR68085.1 - 0.019 14.1 0.1 0.39 9.7 0.1 2.3 1 1 1 2 2 2 0 FAD binding domain DAO PF01266.24 EMR68085.1 - 0.1 12.2 0.5 5.6 6.4 0.0 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase DER1 PF04511.15 EMR68086.1 - 6.3e-51 173.0 6.5 7.3e-51 172.8 6.5 1.0 1 0 0 1 1 1 1 Der1-like family Ribosomal_S10 PF00338.22 EMR68087.1 - 4.6e-26 90.9 0.0 8e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FAM75 PF14650.6 EMR68087.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 FAM75 family Peptidase_M35 PF02102.15 EMR68088.1 - 3.8e-24 85.2 1.6 4.9e-24 84.9 1.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EMR68088.1 - 0.0037 17.8 0.7 0.0064 17.0 0.5 1.5 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase DnaJ_C PF01556.18 EMR68089.1 - 4.8e-36 124.1 0.0 6.9e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMR68089.1 - 2.7e-25 88.3 3.8 4.8e-25 87.5 3.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMR68089.1 - 1.7e-13 50.7 17.8 3.3e-13 49.8 17.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EMR68089.1 - 0.00082 19.3 9.7 0.22 11.5 2.2 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Val_tRNA-synt_C PF10458.9 EMR68089.1 - 0.011 16.0 1.0 0.02 15.1 1.0 1.4 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm RPT PF13446.6 EMR68089.1 - 0.056 13.4 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 A repeated domain in UCH-protein HypA PF01155.19 EMR68089.1 - 0.13 12.3 6.3 3 7.9 1.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 EMR68089.1 - 0.21 10.8 0.6 2.8 7.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) zf-RING_10 PF16685.5 EMR68089.1 - 0.43 10.7 8.0 2 8.6 0.5 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 EMR68089.1 - 2.2 8.3 7.5 6.5 6.8 2.0 2.3 2 0 0 2 2 2 0 zinc-ribbons PIGA PF08288.12 EMR68090.1 - 1.4e-46 157.0 2.7 2.1e-46 156.4 0.6 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EMR68090.1 - 7.5e-28 97.7 0.2 1.4e-27 96.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EMR68090.1 - 1.6e-27 96.1 0.0 2.6e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMR68090.1 - 2.3e-22 79.9 0.1 6.1e-22 78.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMR68090.1 - 2.2e-12 47.7 0.0 5.2e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EMR68090.1 - 4.3e-05 23.6 0.1 7.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EMR68090.1 - 0.00035 20.9 0.1 0.0021 18.4 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 VWA_2 PF13519.6 EMR68093.1 - 4.2e-07 30.6 1.2 2.1e-06 28.4 0.0 2.7 2 1 1 3 3 3 1 von Willebrand factor type A domain DUF3584 PF12128.8 EMR68093.1 - 0.023 12.3 23.0 0.036 11.6 23.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 EMR68093.1 - 0.085 13.0 28.6 0.085 13.0 13.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Lumazine_bd_2 PF12893.7 EMR68093.1 - 0.12 13.1 0.8 0.32 11.7 0.3 2.0 1 1 0 1 1 1 0 Putative lumazine-binding LMBR1 PF04791.16 EMR68093.1 - 0.25 10.2 9.5 0.34 9.8 9.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Lebercilin PF15619.6 EMR68093.1 - 0.3 10.7 33.1 0.073 12.7 10.6 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EMR68093.1 - 0.54 9.1 31.9 5.6 5.7 17.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4455 PF14643.6 EMR68093.1 - 0.59 8.7 25.0 0.0072 15.0 5.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) Fib_alpha PF08702.10 EMR68093.1 - 0.72 10.0 20.2 0.19 11.9 7.1 3.6 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Tropomyosin PF00261.20 EMR68093.1 - 0.82 9.0 31.9 0.011 15.1 16.8 2.2 1 1 1 2 2 2 0 Tropomyosin GIDA_assoc PF13932.6 EMR68093.1 - 1.1 9.4 10.6 2.4 8.3 10.6 1.6 1 0 0 1 1 1 0 GidA associated domain Lectin_N PF03954.14 EMR68093.1 - 1.4 8.6 11.7 0.83 9.4 1.1 2.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Jnk-SapK_ap_N PF09744.9 EMR68093.1 - 1.9 8.7 34.5 0.51 10.5 1.2 3.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 EMR68093.1 - 2.1 7.7 31.0 0.045 13.2 13.2 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF1977 PF09320.11 EMR68093.1 - 2.3 8.5 9.4 0.19 12.0 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) DUF4407 PF14362.6 EMR68093.1 - 3.1 7.1 25.5 7.6 5.8 7.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 EMR68093.1 - 3.3 8.1 37.6 0.81 10.1 14.7 3.6 2 1 2 4 4 3 0 Domain of unknown function (DUF4200) DUF1996 PF09362.10 EMR68094.1 - 3.4e-83 279.2 0.7 4.4e-83 278.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fructosamin_kin PF03881.14 EMR68095.1 - 0.028 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase RepA_C PF04796.12 EMR68095.1 - 0.091 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Plasmid encoded RepA protein GST_N_3 PF13417.6 EMR68096.1 - 2.2e-11 44.0 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR68096.1 - 2.5e-06 27.4 0.5 4.3e-06 26.7 0.5 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR68096.1 - 0.0018 18.5 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR68096.1 - 0.0032 17.7 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR68096.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Helicase_C PF00271.31 EMR68097.1 - 9.7e-21 74.2 0.0 2.5e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMR68097.1 - 4e-14 52.8 0.0 6.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AltA1 PF16541.5 EMR68098.1 - 1.2e-08 35.8 3.9 2.9e-06 28.1 1.1 2.4 2 0 0 2 2 2 2 Alternaria alternata allergen 1 DUF4231 PF14015.6 EMR68098.1 - 0.14 12.7 0.3 0.21 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) AAA_5 PF07728.14 EMR68099.1 - 1.4e-10 41.4 0.0 2.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMR68099.1 - 1.7e-10 41.3 0.0 3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 EMR68099.1 - 2e-06 27.8 0.0 8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EMR68099.1 - 6.7e-06 26.6 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR68099.1 - 0.013 15.9 0.0 0.12 12.7 0.0 2.4 2 1 1 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 EMR68099.1 - 0.021 14.2 0.0 2.7 7.3 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EMR68099.1 - 0.044 14.1 0.0 0.28 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain Tyrosinase PF00264.20 EMR68100.1 - 3.4e-33 115.8 2.2 3.4e-33 115.8 2.2 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase DUF3570 PF12094.8 EMR68100.1 - 0.00096 18.0 0.1 0.0013 17.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3570) PrlF_antitoxin PF15937.5 EMR68100.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin adh_short PF00106.25 EMR68101.1 - 5.4e-31 107.6 0.1 6.6e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68101.1 - 2.4e-24 86.2 0.0 3.1e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68101.1 - 1e-07 32.1 1.2 1.5e-07 31.5 1.2 1.2 1 0 0 1 1 1 1 KR domain CRISPR_assoc PF08798.11 EMR68101.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 CRISPR associated protein MtrD PF04207.12 EMR68101.1 - 0.19 11.4 1.8 2.5 7.7 0.6 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D NAD_binding_10 PF13460.6 EMR68101.1 - 0.51 10.2 3.5 6.9 6.5 3.5 2.2 1 1 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 EMR68102.1 - 2.2e-25 89.3 0.0 4.6e-23 81.7 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68102.1 - 1.1e-13 51.4 0.0 1.9e-13 50.5 0.1 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR68102.1 - 6.6e-07 29.0 0.0 9.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR68102.1 - 3.2e-06 27.2 0.1 5.5e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR68102.1 - 9.2e-05 22.0 0.1 0.00024 20.6 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Prp19 PF08606.11 EMR68102.1 - 0.005 16.8 0.1 0.0088 16.0 0.1 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like Shikimate_DH PF01488.20 EMR68102.1 - 0.015 15.4 0.1 0.021 14.9 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EMR68102.1 - 0.033 14.1 0.3 0.12 12.3 0.3 1.8 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 EMR68102.1 - 0.036 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 EMR68102.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ecm29 PF13001.7 EMR68103.1 - 1.6e-83 281.1 0.8 2.3e-42 145.3 0.0 3.7 3 1 0 3 3 3 2 Proteasome stabiliser HEAT_EZ PF13513.6 EMR68103.1 - 3e-05 24.4 2.6 4.7 7.8 0.0 7.6 8 1 1 9 9 9 1 HEAT-like repeat HEAT PF02985.22 EMR68103.1 - 0.00079 19.5 8.7 1.4 9.4 0.0 6.9 7 0 0 7 7 7 1 HEAT repeat IFRD PF05004.13 EMR68103.1 - 0.05 12.7 8.7 0.83 8.7 0.1 4.5 4 1 0 5 5 5 0 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 EMR68103.1 - 0.13 12.1 0.1 0.64 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Fungal_trans PF04082.18 EMR68104.1 - 0.00016 20.8 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4913 PF16259.5 EMR68104.1 - 0.083 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) GPW_gp25 PF04965.14 EMR68104.1 - 0.1 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Gene 25-like lysozyme Abhydrolase_1 PF00561.20 EMR68106.1 - 3.9e-18 66.0 0.0 7.9e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR68106.1 - 1.4e-11 45.4 0.0 1.9e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR68106.1 - 7e-09 35.3 0.0 4e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EMR68106.1 - 0.023 14.3 0.0 0.07 12.7 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EMR68106.1 - 0.091 12.2 0.2 1 8.8 0.0 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family Bac_rhamnosid6H PF17389.2 EMR68107.1 - 2e-44 152.3 2.0 5.2e-34 118.0 0.4 3.0 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EMR68107.1 - 8.8e-24 84.2 2.9 3e-19 69.5 0.0 3.1 2 1 1 3 3 3 2 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 EMR68107.1 - 0.00029 20.8 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain MFS_1 PF07690.16 EMR68108.1 - 3.2e-18 65.8 26.6 3.2e-18 65.8 26.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR68108.1 - 1.1e-08 34.0 5.8 1.6e-08 33.5 5.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4153 PF13687.6 EMR68108.1 - 0.018 14.6 0.7 0.03 14.0 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4153) DUF3438 PF11920.8 EMR68108.1 - 0.033 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) SNF2_N PF00176.23 EMR68109.1 - 2.5e-49 167.9 0.4 4.3e-49 167.1 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR68109.1 - 9.7e-19 67.8 0.0 6.9e-18 65.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR68109.1 - 3.4e-11 43.4 0.0 7.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMR68109.1 - 0.00045 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 EMR68109.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 HSA PF07529.13 EMR68109.1 - 1.2 9.5 17.1 0.034 14.5 6.9 3.0 3 0 0 3 3 3 0 HSA NDUF_B8 PF05821.11 EMR68111.1 - 4.4e-08 33.2 0.3 7.6e-08 32.4 0.3 1.5 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cupin_2 PF07883.11 EMR68113.1 - 2.3e-09 36.9 0.0 3.4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EMR68113.1 - 0.0041 16.8 0.0 0.0046 16.6 0.0 1.3 1 1 0 1 1 1 1 Cupin DUF4437 PF14499.6 EMR68113.1 - 0.088 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Cupin_7 PF12973.7 EMR68113.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain FAD_binding_3 PF01494.19 EMR68114.1 - 1.4e-19 70.6 0.1 2.6e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR68114.1 - 1.8e-05 24.5 0.4 0.065 12.8 0.3 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR68114.1 - 7.4e-05 22.1 0.0 0.021 14.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GST_N_2 PF13409.6 EMR68114.1 - 0.0016 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pyr_redox PF00070.27 EMR68114.1 - 0.0075 16.8 0.0 0.022 15.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GST_N_3 PF13417.6 EMR68114.1 - 0.011 16.1 0.1 0.027 14.9 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NAD_binding_8 PF13450.6 EMR68114.1 - 0.013 15.7 1.5 0.021 15.0 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 EMR68114.1 - 0.018 14.7 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GST_C_2 PF13410.6 EMR68114.1 - 0.054 13.5 0.0 0.22 11.6 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain YchF-GTPase_C PF06071.13 EMR68115.1 - 1.6e-31 108.3 0.0 4e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EMR68115.1 - 3.4e-21 75.4 0.0 7.2e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMR68115.1 - 9.5e-08 31.7 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Thioredoxin_7 PF13899.6 EMR68116.1 - 2.1e-16 59.8 0.0 6.5e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 EMR68116.1 - 7.7e-12 44.8 0.0 1.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EMR68116.1 - 1.1e-05 25.5 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 EMR68116.1 - 0.0056 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Prothymosin PF03247.14 EMR68116.1 - 1.3 9.5 8.2 2.8 8.4 8.2 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family Cwf_Cwc_15 PF04889.12 EMR68116.1 - 1.4 8.6 6.5 2.5 7.7 6.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DnaJ PF00226.31 EMR68118.1 - 1.8e-08 34.4 1.8 3.6e-08 33.4 0.1 2.4 3 0 0 3 3 3 1 DnaJ domain MIP PF00230.20 EMR68119.1 - 1.9e-31 109.5 2.5 2.5e-31 109.1 2.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4360 PF14273.6 EMR68120.1 - 2.2e-25 89.6 0.0 2.7e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RRM_1 PF00076.22 EMR68121.1 - 2.3e-45 152.2 0.0 8.5e-16 57.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMR68121.1 - 1.6e-06 28.0 0.0 0.0021 18.0 0.1 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EMR68121.1 - 2.5e-05 24.3 0.0 0.0023 18.0 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 EMR68121.1 - 9.1e-05 22.5 0.2 0.05 13.7 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 EMR68121.1 - 0.0022 17.8 0.0 0.51 10.2 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EMR68121.1 - 0.0095 16.2 0.2 3 8.1 0.0 3.2 3 1 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter Syntaxin-6_N PF09177.11 EMR68122.1 - 0.17 12.5 0.3 2 9.0 0.0 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF5597 PF18120.1 EMR68123.1 - 3.2e-29 101.7 0.0 4.8e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 EMR68123.1 - 8.8e-08 31.9 0.0 4.6e-06 26.2 0.0 2.5 2 1 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.19 EMR68123.1 - 0.0013 18.5 0.0 1.3 8.6 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 35 BNR_2 PF13088.6 EMR68124.1 - 0.00039 19.8 0.4 0.041 13.2 0.4 2.6 1 1 0 1 1 1 1 BNR repeat-like domain DUF4185 PF13810.6 EMR68124.1 - 0.0011 18.2 4.7 0.23 10.7 0.1 3.0 1 1 0 2 2 2 2 Domain of unknown function (DUF4185) BNR PF02012.20 EMR68124.1 - 0.098 12.7 12.8 1.1 9.6 2.7 3.8 3 0 0 3 3 3 0 BNR/Asp-box repeat Ribonuc_L-PSP PF01042.21 EMR68125.1 - 3.3e-06 27.1 0.0 7.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Endoribonuclease L-PSP Cytochrom_C_asm PF01578.20 EMR68126.1 - 0.00016 21.5 0.7 0.00022 21.0 0.7 1.1 1 0 0 1 1 1 1 Cytochrome C assembly protein DUF2427 PF10348.9 EMR68126.1 - 0.01 15.6 5.3 0.023 14.5 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Wzy_C PF04932.15 EMR68126.1 - 0.021 14.4 4.4 0.76 9.4 2.7 2.4 1 1 1 2 2 2 0 O-Antigen ligase Cytochrom_B561 PF03188.16 EMR68126.1 - 0.034 14.3 5.1 0.15 12.2 5.5 1.9 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF2776 PF10951.8 EMR68126.1 - 0.28 10.4 3.4 0.61 9.3 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2776) DUF3040 PF11239.8 EMR68126.1 - 0.5 10.7 0.0 0.5 10.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) NINJA_B PF16136.5 EMR68126.1 - 1.3 9.4 3.1 0.5 10.7 0.5 1.6 2 0 0 2 2 2 0 Putative nuclear localisation signal CDC45 PF02724.14 EMR68126.1 - 4.7 5.4 5.9 7.5 4.7 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_1 PF00561.20 EMR68128.1 - 6.3e-12 45.7 0.0 2.7e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR68128.1 - 5.7e-07 29.0 0.0 2e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR68128.1 - 4.6e-06 27.4 0.2 5.8e-06 27.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EMR68128.1 - 0.0068 15.1 0.0 0.0088 14.8 0.0 1.4 1 1 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 EMR68128.1 - 0.077 12.8 0.0 3.2 7.5 0.0 2.6 2 1 1 3 3 3 0 Alpha/beta hydrolase family Dynamin_N PF00350.23 EMR68130.1 - 1.8e-14 54.2 2.9 2.9e-14 53.5 0.0 2.8 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EMR68130.1 - 1.8e-05 24.8 0.0 0.00026 21.1 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR68130.1 - 0.00024 21.1 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EMR68130.1 - 0.0015 19.1 1.6 0.0024 18.4 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 EMR68130.1 - 0.014 15.6 0.2 0.47 10.7 0.0 3.7 3 1 0 3 3 3 0 AAA domain IIGP PF05049.13 EMR68130.1 - 0.056 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 EMR68130.1 - 0.074 12.4 0.0 0.22 10.8 0.0 1.8 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 EMR68130.1 - 0.17 12.3 0.0 0.17 12.3 0.0 3.7 3 1 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 EMR68130.1 - 0.76 10.2 0.0 0.76 10.2 0.0 3.5 2 1 0 2 2 1 0 AAA domain DUF4140 PF13600.6 EMR68130.1 - 2 8.9 6.8 22 5.6 0.4 3.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.14 EMR68130.1 - 2 8.2 9.7 2.7 7.8 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.11 EMR68130.1 - 5.5 7.6 9.6 14 6.3 0.2 4.4 4 0 0 4 4 4 0 Syntaxin 6, N-terminal zf-MYND PF01753.18 EMR68131.1 - 1.5e-07 31.4 8.9 2.9e-07 30.5 8.9 1.5 1 0 0 1 1 1 1 MYND finger adh_short PF00106.25 EMR68132.1 - 1.2e-36 126.0 0.0 1.8e-35 122.2 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68132.1 - 1.9e-26 93.1 0.0 1.5e-25 90.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68132.1 - 4.7e-06 26.6 0.1 0.0034 17.3 0.1 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EMR68132.1 - 3.2e-05 23.5 0.0 4.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMR68132.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CorA PF01544.18 EMR68133.1 - 2.6e-08 33.5 1.0 5.7e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF3591 PF12157.8 EMR68133.1 - 0.065 11.9 0.0 0.094 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) Glyco_hydro_61 PF03443.14 EMR68134.1 - 1.4e-59 201.5 0.1 2.2e-59 200.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sugar_tr PF00083.24 EMR68135.1 - 1.6e-65 221.8 19.9 8.7e-43 146.8 4.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR68135.1 - 2e-12 46.7 34.9 1.8e-10 40.3 32.8 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 EMR68135.1 - 0.86 10.0 9.7 0.3 11.4 1.1 3.1 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Aconitase PF00330.20 EMR68136.1 - 2.9e-161 537.6 0.0 3.5e-161 537.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMR68136.1 - 5.3e-41 140.0 0.0 9.5e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Abhydrolase_1 PF00561.20 EMR68137.1 - 2.7e-22 79.6 0.0 9.8e-22 77.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR68137.1 - 5.2e-14 53.4 0.0 6.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR68137.1 - 0.00041 19.7 0.0 0.0069 15.7 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BTB PF00651.31 EMR68138.1 - 3e-06 27.4 0.1 1.1e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DSBA PF01323.20 EMR68139.1 - 3.7e-23 82.3 0.1 4.3e-23 82.1 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EMR68139.1 - 0.001 19.2 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Cullin PF00888.22 EMR68140.1 - 1.9e-191 637.9 1.5 1.9e-191 637.9 1.5 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EMR68140.1 - 1.4e-24 85.9 0.8 3.8e-24 84.5 0.8 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Lipase_GDSL_2 PF13472.6 EMR68141.1 - 1.9e-11 44.7 0.6 2.6e-11 44.3 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR68141.1 - 6.8e-05 22.9 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EMR68141.1 - 0.0055 16.9 0.0 0.01 16.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GH131_N PF18271.1 EMR68142.1 - 2.6e-72 243.6 0.3 3e-72 243.4 0.3 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain DicB PF05358.11 EMR68142.1 - 0.2 11.8 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 DicB protein YbjQ_1 PF01906.17 EMR68144.1 - 1.1e-09 38.9 0.0 1.4e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Putative heavy-metal-binding zf-DNL PF05180.12 EMR68145.1 - 5.7e-27 93.4 0.1 8.9e-27 92.8 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 EMR68145.1 - 0.015 15.0 0.2 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger NTPase_1 PF03266.15 EMR68145.1 - 0.041 13.8 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 NTPase UPF0167 PF03691.14 EMR68145.1 - 0.21 11.4 0.0 8.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) SH3_1 PF00018.28 EMR68146.1 - 6e-09 35.4 0.0 1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMR68146.1 - 1.5e-07 31.2 0.1 3.2e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMR68146.1 - 0.00011 21.8 0.0 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FAD-oxidase_C PF02913.19 EMR68147.1 - 8e-09 35.5 0.1 9.6e-09 35.2 0.1 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DUF4058 PF13267.6 EMR68147.1 - 0.2 11.0 0.0 8 5.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4058) Cyclin_C PF02984.19 EMR68149.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain Ssu72 PF04722.13 EMR68150.1 - 6.5e-84 280.3 0.0 7.5e-84 280.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF3638 PF12340.8 EMR68150.1 - 0.22 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Trypan_PARP PF05887.11 EMR68151.1 - 0.011 15.7 5.5 0.026 14.5 5.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 EMR68151.1 - 0.14 10.4 3.5 0.21 9.9 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SPESP1 PF15754.5 EMR68151.1 - 0.41 9.8 3.5 0.66 9.1 3.5 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 EspB PF05802.11 EMR68152.1 - 0.00046 20.2 3.0 0.00046 20.2 3.0 4.5 3 2 2 5 5 4 1 Enterobacterial EspB protein SARAF PF06682.12 EMR68152.1 - 0.0048 16.6 0.8 0.013 15.2 0.8 1.8 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Rootletin PF15035.6 EMR68152.1 - 0.0077 16.3 12.1 0.0077 16.3 12.1 3.5 3 1 0 3 3 3 1 Ciliary rootlet component, centrosome cohesion CLZ PF16526.5 EMR68152.1 - 0.012 15.9 0.7 0.012 15.9 0.7 4.8 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 EMR68152.1 - 0.022 14.8 13.6 0.036 14.2 0.0 4.3 4 0 0 4 4 4 0 bZIP transcription factor FlaC_arch PF05377.11 EMR68152.1 - 0.25 11.8 8.5 4 7.9 0.1 4.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 EMR68152.1 - 0.8 10.4 30.6 4 8.1 0.8 6.5 5 1 1 6 6 6 0 SlyX PSII_Pbs27 PF13326.6 EMR68152.1 - 0.95 9.8 8.8 0.5 10.7 0.4 3.1 3 0 0 3 3 3 0 Photosystem II Pbs27 HSBP1 PF06825.12 EMR68152.1 - 1.1 9.1 8.3 10 6.1 3.5 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Cor1 PF04803.12 EMR68152.1 - 6.2 7.0 23.9 0.62 10.3 2.6 3.8 3 1 0 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF948 PF06103.11 EMR68152.1 - 6.9 7.0 13.8 87 3.5 1.3 4.9 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Pro_dh PF01619.18 EMR68153.1 - 1.1e-61 208.9 0.0 1.8e-61 208.3 0.0 1.3 1 1 0 1 1 1 1 Proline dehydrogenase Sugar_tr PF00083.24 EMR68154.1 - 4e-116 388.5 23.1 4.6e-116 388.3 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR68154.1 - 7.6e-22 77.7 27.9 1.8e-14 53.5 6.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily CGI-121 PF08617.10 EMR68155.1 - 6.5e-53 179.2 0.1 7.6e-53 178.9 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Stork_head PF10264.9 EMR68155.1 - 0.074 13.2 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Cytokin_check_N PF10407.9 EMR68156.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Rad60-SLD PF11976.8 EMR68156.1 - 0.15 11.9 0.0 4.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Fungal_trans PF04082.18 EMR68157.1 - 2e-14 53.2 0.1 3.6e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR68157.1 - 0.00013 22.0 0.7 0.00034 20.7 0.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EMR68158.1 - 7e-15 55.1 0.0 2e-09 37.2 0.0 2.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR68158.1 - 6.5e-08 32.2 0.0 3.5e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EMR68158.1 - 0.0015 18.5 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EMR68158.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EMR68158.1 - 0.17 11.1 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Sec61_beta PF03911.16 EMR68159.1 - 6.5e-19 67.7 1.8 8.9e-19 67.2 1.8 1.2 1 0 0 1 1 1 1 Sec61beta family adh_short PF00106.25 EMR68160.1 - 2.6e-25 89.0 0.0 7.1e-24 84.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68160.1 - 1.8e-13 50.6 0.0 3.2e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68160.1 - 3.6e-08 33.5 0.0 5.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAPRTase PF04095.16 EMR68161.1 - 2.3e-54 184.6 0.0 2.8e-29 102.4 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EMR68161.1 - 1.8e-35 122.1 0.0 3.1e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain p450 PF00067.22 EMR68162.1 - 2.1e-41 142.2 0.0 2.6e-29 102.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 KH_1 PF00013.29 EMR68164.1 - 2.1e-10 40.2 0.0 5.3e-08 32.6 0.0 2.7 2 0 0 2 2 2 2 KH domain ATLF PF07737.11 EMR68164.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain tRNA-synt_2d PF01409.20 EMR68165.1 - 6.6e-84 281.2 0.0 1.8e-83 279.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EMR68165.1 - 6.8e-18 64.7 1.0 1.6e-17 63.5 1.0 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EMR68165.1 - 3e-06 26.8 0.0 0.007 15.8 0.0 2.6 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EMR68165.1 - 0.00036 19.7 2.2 0.0033 16.6 0.0 3.0 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 EMR68165.1 - 0.0095 15.9 2.3 0.046 13.7 2.3 2.3 1 1 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 EMR68165.1 - 0.02 14.9 0.0 0.13 12.2 0.0 2.2 1 1 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF3712 PF12505.8 EMR68166.1 - 3.4e-09 37.0 0.3 5.7e-08 33.1 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) adh_short PF00106.25 EMR68167.1 - 4.3e-09 36.1 0.0 2.2e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68167.1 - 0.00015 21.4 0.0 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase OTCace_N PF02729.21 EMR68168.1 - 8e-47 159.0 0.2 1.1e-46 158.5 0.2 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EMR68168.1 - 1.2e-40 139.1 0.0 2e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ACT PF01842.25 EMR68169.1 - 3e-15 55.7 0.1 5.6e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 EMR68169.1 - 1.2e-14 54.3 0.0 2.8e-13 49.9 0.0 2.5 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 EMR68169.1 - 1.6e-08 34.2 0.1 3.6e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 EMR68169.1 - 0.14 12.2 0.0 25 4.9 0.0 2.5 2 0 0 2 2 2 0 ACT domain Pkinase PF00069.25 EMR68170.1 - 0.055 12.8 0.0 1.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Protein kinase domain Arginase PF00491.21 EMR68171.1 - 2.7e-74 250.2 0.5 3.2e-74 249.9 0.5 1.0 1 0 0 1 1 1 1 Arginase family FAD_binding_4 PF01565.23 EMR68172.1 - 1.2e-21 77.0 0.9 2.8e-21 75.7 0.9 1.7 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 EMR68172.1 - 8.8e-07 29.0 12.2 1.7e-06 28.1 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR68172.1 - 2.7e-06 26.6 0.0 6.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mating_N PF12731.7 EMR68172.1 - 0.034 14.2 0.4 3.6 7.8 0.1 3.1 3 0 0 3 3 3 0 Mating-type protein beta 1 Lipase_2 PF01674.18 EMR68176.1 - 2.9e-06 27.0 0.0 8.9e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_6 PF12697.7 EMR68176.1 - 5e-06 27.3 0.4 7e-06 26.8 0.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR68176.1 - 1.2e-05 24.7 0.1 1.6e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR68176.1 - 2.3e-05 24.2 0.0 5.5e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 EMR68176.1 - 0.00099 18.7 0.0 0.0021 17.6 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EMR68176.1 - 0.009 15.9 0.0 0.032 14.1 0.0 1.7 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_8 PF06259.12 EMR68176.1 - 0.014 15.1 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.13 EMR68176.1 - 0.029 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 EMR68176.1 - 0.055 12.8 0.0 2.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.8 EMR68176.1 - 0.076 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Smg4_UPF3 PF03467.15 EMR68177.1 - 2.1e-12 47.4 0.0 2.8e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family Peptidase_M64 PF09471.10 EMR68179.1 - 0.1 12.1 1.0 0.32 10.5 0.2 1.9 1 1 1 2 2 2 0 IgA Peptidase M64 Zincin_1 PF06262.11 EMR68179.1 - 0.21 11.7 0.1 0.64 10.2 0.1 1.7 2 0 0 2 2 2 0 Zincin-like metallopeptidase GDPD PF03009.17 EMR68180.1 - 1.8e-35 123.0 0.0 2.1e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ras PF00071.22 EMR68181.1 - 1e-47 161.8 0.0 1.3e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR68181.1 - 7e-21 74.7 0.0 1.3e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR68181.1 - 5.9e-06 25.9 0.0 2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EMR68181.1 - 0.043 13.3 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EMR68181.1 - 0.043 13.2 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Metallophos PF00149.28 EMR68182.1 - 3.8e-33 115.7 0.0 1.2e-28 101.0 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EMR68182.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Peptidase_M9_N PF08453.10 EMR68183.1 - 0.069 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal DUF848 PF05852.11 EMR68183.1 - 0.27 11.3 3.3 0.76 9.9 0.3 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SBP56 PF05694.11 EMR68184.1 - 3.8e-06 26.0 0.0 5e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 EMR68184.1 - 0.0027 17.0 0.1 0.16 11.2 0.3 2.5 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EMR68184.1 - 0.027 14.0 0.0 0.97 9.0 0.0 2.7 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region GRP PF07172.11 EMR68185.1 - 0.0018 18.9 10.4 0.0036 17.9 10.4 1.4 1 0 0 1 1 1 1 Glycine rich protein family Pkinase PF00069.25 EMR68186.1 - 4.5e-09 36.1 0.0 3.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR68186.1 - 0.00081 18.8 0.0 0.068 12.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase adh_short PF00106.25 EMR68187.1 - 5.8e-11 42.2 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68187.1 - 6.6e-06 25.9 0.4 2.1e-05 24.2 0.5 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68187.1 - 0.00046 20.2 0.7 0.00067 19.6 0.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR68187.1 - 0.0011 18.9 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Spt46 PF17734.1 EMR68188.1 - 0.12 12.2 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 Smg4_UPF3 PF03467.15 EMR68189.1 - 4.1e-20 72.5 1.9 4.1e-20 72.5 1.9 4.6 4 2 0 4 4 4 1 Smg-4/UPF3 family RRM_1 PF00076.22 EMR68189.1 - 2.3e-05 24.1 0.2 0.0003 20.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U79_P34 PF03064.16 EMR68189.1 - 1.8 7.8 25.9 0.034 13.5 6.9 2.5 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Skp1_POZ PF03931.15 EMR68190.1 - 2.3e-09 37.3 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain TRF PF08558.10 EMR68191.1 - 1.8e-38 132.5 0.1 2.9e-38 131.8 0.1 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) DUF1041 PF06292.17 EMR68191.1 - 0.13 12.7 0.2 12 6.4 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) Rho_N PF07498.12 EMR68191.1 - 0.36 10.8 2.2 6.9 6.7 0.3 2.5 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Aldedh PF00171.22 EMR68192.1 - 7.5e-185 614.9 0.0 8.4e-185 614.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 EMR68193.1 - 7.3e-26 90.9 18.8 3.9e-25 88.5 19.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR68193.1 - 1.2e-06 28.2 2.1 1.9e-06 27.4 2.1 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ATG16 PF08614.11 EMR68194.1 - 0.00062 20.1 10.3 0.01 16.1 6.5 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) YabA PF06156.13 EMR68194.1 - 0.0027 18.3 6.2 0.41 11.3 1.1 2.8 1 1 1 2 2 2 2 Initiation control protein YabA ZapB PF06005.12 EMR68194.1 - 0.0032 17.9 10.9 0.27 11.7 2.4 3.6 2 1 1 3 3 3 1 Cell division protein ZapB Rootletin PF15035.6 EMR68194.1 - 0.0047 17.0 11.0 0.017 15.2 7.9 2.2 1 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 EMR68194.1 - 0.0061 16.7 12.6 1.7 8.7 12.6 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EMR68194.1 - 0.0077 15.1 9.8 0.0071 15.3 8.3 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin PF00261.20 EMR68194.1 - 0.009 15.4 4.5 0.009 15.4 4.5 2.2 1 1 1 2 2 2 1 Tropomyosin DUF2046 PF09755.9 EMR68194.1 - 0.009 15.3 5.7 0.018 14.3 5.7 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Lebercilin PF15619.6 EMR68194.1 - 0.018 14.7 12.1 0.02 14.5 8.3 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.19 EMR68194.1 - 0.019 12.9 3.7 0.023 12.6 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lectin_N PF03954.14 EMR68194.1 - 0.022 14.5 1.4 0.035 13.8 1.4 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4201 PF13870.6 EMR68194.1 - 0.026 14.3 13.9 1.3 8.7 8.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 EMR68194.1 - 0.026 14.7 8.2 1.4 9.1 4.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 EMR68194.1 - 0.029 14.6 8.0 2.5 8.4 0.4 3.9 2 2 2 4 4 4 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 EMR68194.1 - 0.039 13.8 7.9 0.12 12.1 7.9 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SIKE PF05769.11 EMR68194.1 - 0.049 13.6 6.1 0.064 13.2 4.7 1.8 1 1 1 2 2 2 0 SIKE family PRKG1_interact PF15898.5 EMR68194.1 - 0.05 14.5 10.1 0.13 13.2 6.3 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain BLOC1_2 PF10046.9 EMR68194.1 - 0.054 13.8 9.8 11 6.3 0.3 3.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Plasmid_RAQPRD PF09686.10 EMR68194.1 - 0.089 13.0 0.6 0.089 13.0 0.6 2.2 2 1 1 3 3 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF1664 PF07889.12 EMR68194.1 - 0.11 12.5 5.0 3.7 7.6 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EMR68194.1 - 0.13 12.5 3.4 0.44 10.8 0.1 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF848 PF05852.11 EMR68194.1 - 0.15 12.2 8.1 0.071 13.2 3.2 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) APG6_N PF17675.1 EMR68194.1 - 0.18 12.3 11.9 4.9 7.7 11.8 2.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Nup88 PF10168.9 EMR68194.1 - 0.19 9.5 5.3 0.24 9.2 5.3 1.2 1 0 0 1 1 1 0 Nuclear pore component CENP-H PF05837.12 EMR68194.1 - 0.22 12.0 11.5 0.21 12.0 4.3 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DivIVA PF05103.13 EMR68194.1 - 0.25 11.4 11.3 0.83 9.7 9.7 2.2 1 1 1 2 2 2 0 DivIVA protein PLAC9 PF15205.6 EMR68194.1 - 0.25 11.7 0.5 0.73 10.3 0.0 1.9 2 0 0 2 2 1 0 Placenta-specific protein 9 TMF_TATA_bd PF12325.8 EMR68194.1 - 0.29 11.4 7.1 0.85 9.9 0.7 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF445 PF04286.12 EMR68194.1 - 0.29 10.9 5.7 2.9 7.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Cauli_AT PF03233.13 EMR68194.1 - 0.31 11.0 2.9 0.33 10.8 1.1 1.9 1 1 1 2 2 2 0 Aphid transmission protein Cnn_1N PF07989.11 EMR68194.1 - 0.32 11.2 5.2 3.8 7.7 0.3 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 MPS2 PF17060.5 EMR68194.1 - 0.36 10.0 9.0 0.13 11.5 6.2 1.4 1 1 1 2 2 2 0 Monopolar spindle protein 2 DUF4515 PF14988.6 EMR68194.1 - 0.38 10.6 11.8 0.13 12.0 2.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4515) DivIC PF04977.15 EMR68194.1 - 0.44 10.4 13.3 1 9.1 0.9 3.4 1 1 2 3 3 3 0 Septum formation initiator Cep57_MT_bd PF06657.13 EMR68194.1 - 0.45 11.0 7.9 4.1 7.9 2.5 3.1 2 2 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Atg14 PF10186.9 EMR68194.1 - 0.46 9.5 8.6 0.65 9.0 8.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 EMR68194.1 - 0.47 10.9 2.2 12 6.3 0.1 3.1 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 EMR68194.1 - 0.79 10.3 7.5 2.3 8.8 3.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TSC22 PF01166.18 EMR68194.1 - 0.83 10.0 3.8 8.9 6.7 0.5 3.4 2 2 2 4 4 4 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 EMR68194.1 - 1.2 9.1 7.2 1.2 9.1 4.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 EMR68194.1 - 1.5 8.1 9.8 3.1 7.1 9.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 EMR68194.1 - 1.5 9.1 4.8 1.1 9.6 0.7 2.6 1 1 2 3 3 3 0 ABC transporter C-terminal domain bZIP_2 PF07716.15 EMR68194.1 - 1.6 8.9 12.3 1.9 8.7 0.8 4.3 4 1 0 4 4 4 0 Basic region leucine zipper APC_N_CC PF16689.5 EMR68194.1 - 1.7 8.7 5.3 44 4.2 0.0 3.2 2 1 2 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain Csm1_N PF18504.1 EMR68194.1 - 2.1 8.7 11.3 2.4 8.6 2.5 3.3 2 1 2 4 4 3 0 Csm1 N-terminal domain Mto2_bdg PF12808.7 EMR68194.1 - 2.6 8.4 7.8 5.1 7.5 1.1 3.4 2 2 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TMPIT PF07851.13 EMR68194.1 - 3.4 6.8 7.3 17 4.5 0.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF2570 PF10828.8 EMR68194.1 - 3.5 7.5 6.5 4.4 7.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF724 PF05266.14 EMR68194.1 - 5.7 6.7 9.5 2.1 8.1 3.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF4200 PF13863.6 EMR68194.1 - 8.2 6.9 14.3 32 4.9 10.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF5103 PF17116.5 EMR68195.1 - 0.031 13.6 0.1 0.056 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) DASH_Dad1 PF08649.10 EMR68196.1 - 1.3e-27 95.7 1.9 1.8e-27 95.3 1.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EMR68196.1 - 0.069 13.1 0.3 0.099 12.6 0.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 V_ATPase_I PF01496.19 EMR68196.1 - 0.2 9.5 0.0 0.22 9.4 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cupin_1 PF00190.22 EMR68197.1 - 5.4e-38 130.0 0.0 2.7e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EMR68197.1 - 9.6e-22 76.5 0.9 6.1e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EMR68197.1 - 5.3e-08 32.4 0.1 0.0031 17.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EMR68197.1 - 2e-05 24.5 1.3 0.12 12.2 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Putative_PNPOx PF01243.20 EMR68198.1 - 1.5e-05 25.1 0.0 3.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Neocarzinostat PF00960.18 EMR68198.1 - 0.16 11.9 0.1 0.3 11.1 0.1 1.3 1 0 0 1 1 1 0 Neocarzinostatin family C2 PF00168.30 EMR68199.1 - 3.8e-18 65.7 0.0 9.3e-14 51.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 EMR68199.1 - 3e-14 52.9 0.0 1.3e-09 37.8 0.0 2.2 1 1 1 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain DUF2353 PF09789.9 EMR68200.1 - 0.025 14.0 4.9 0.033 13.6 4.9 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) GAS PF13851.6 EMR68200.1 - 0.12 11.7 7.8 0.23 10.8 7.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 EMR68200.1 - 0.57 10.3 9.6 3.5 7.7 6.4 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.20 EMR68200.1 - 0.58 10.1 4.5 6.6 6.7 0.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit UPF0242 PF06785.11 EMR68200.1 - 0.67 10.0 5.0 1.2 9.2 5.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Bap31_Bap29_C PF18035.1 EMR68200.1 - 0.74 9.9 5.5 0.56 10.2 1.5 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 EMR68200.1 - 1 9.6 6.3 2.4 8.5 6.3 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4407 PF14362.6 EMR68200.1 - 1.1 8.6 11.4 2.8 7.2 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 EMR68200.1 - 1.1 9.4 6.3 1.9 8.7 6.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 GrpE PF01025.19 EMR68200.1 - 2.2 7.9 7.9 1.4 8.6 0.8 2.2 2 0 0 2 2 2 0 GrpE DivIC PF04977.15 EMR68200.1 - 3.4 7.5 7.4 1.6 8.6 1.9 2.4 2 1 0 2 2 2 0 Septum formation initiator CDC45 PF02724.14 EMR68200.1 - 7.5 4.7 11.5 1 7.6 7.5 1.4 1 1 0 1 1 1 0 CDC45-like protein zf-RING_2 PF13639.6 EMR68201.1 - 8e-08 32.5 13.1 1.3e-07 31.8 13.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EMR68201.1 - 8e-06 25.6 7.7 1.3e-05 25.0 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR68201.1 - 1.5e-05 24.8 10.7 2.1e-05 24.3 10.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMR68201.1 - 0.00016 21.9 8.7 0.00031 21.0 8.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EMR68201.1 - 0.00028 20.7 12.4 0.00045 20.0 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMR68201.1 - 0.1 12.5 6.3 0.17 11.7 6.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1179 PF06678.11 EMR68201.1 - 0.11 12.4 0.8 4.5 7.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1179) DnaJ PF00226.31 EMR68203.1 - 0.0008 19.5 0.5 0.0021 18.1 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Trypan_PARP PF05887.11 EMR68203.1 - 0.00086 19.3 3.8 0.00086 19.3 3.8 2.0 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 EMR68203.1 - 0.0046 17.5 7.3 0.0046 17.5 7.3 2.2 3 0 0 3 3 3 1 TonB polyproline region SPESP1 PF15754.5 EMR68203.1 - 0.095 11.9 0.8 0.18 10.9 0.8 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 LcrG PF07216.12 EMR68203.1 - 1.4 8.9 9.5 0.38 10.7 6.1 1.8 1 1 1 2 2 2 0 LcrG protein RR_TM4-6 PF06459.12 EMR68203.1 - 6.5 6.5 9.1 1 9.1 5.3 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 C1_2 PF03107.16 EMR68203.1 - 7.7 6.9 10.7 14 6.1 10.7 1.4 1 0 0 1 1 1 0 C1 domain Macoilin PF09726.9 EMR68203.1 - 7.9 4.9 11.9 9.8 4.6 11.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF3987 PF13148.6 EMR68203.1 - 8.2 5.3 12.0 14 4.6 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) adh_short PF00106.25 EMR68204.1 - 8.1e-13 48.3 0.0 1.3e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68204.1 - 1.9e-07 30.9 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR68205.1 - 1.6e-19 70.1 0.0 9.2e-17 61.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68205.1 - 6.9e-10 38.9 0.1 2.1e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68205.1 - 3.2e-07 30.4 0.1 4.8e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Macoilin PF09726.9 EMR68206.1 - 0.00016 20.4 4.4 0.00019 20.2 4.4 1.2 1 0 0 1 1 1 1 Macoilin family Apt1 PF10351.9 EMR68206.1 - 0.17 10.7 9.7 0.28 10.0 9.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 EMR68206.1 - 0.31 9.8 4.8 0.46 9.2 4.8 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_M20 PF01546.28 EMR68207.1 - 1.5e-24 86.8 0.1 2e-24 86.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR68207.1 - 1.6e-18 66.6 0.0 2.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMR68207.1 - 0.0017 18.1 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 YidD PF01809.18 EMR68208.1 - 0.29 11.1 2.7 7.9 6.4 3.2 2.4 2 1 0 2 2 2 0 Putative membrane protein insertion efficiency factor NAD_binding_4 PF07993.12 EMR68210.1 - 4.6e-07 29.3 0.0 7.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EMR68210.1 - 5e-06 26.8 0.0 1.2e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EMR68210.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Tox-HDC PF15656.6 EMR68210.1 - 0.092 12.9 0.0 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature Polysacc_synt_2 PF02719.15 EMR68210.1 - 0.095 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EMR68211.1 - 8.2e-17 61.2 13.1 1.2e-16 60.6 13.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Flavin_Reduct PF01613.18 EMR68212.1 - 9.9e-12 45.2 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EMR68212.1 - 0.00067 19.5 0.0 0.00081 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 EMR68212.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Abhydrolase_1 PF00561.20 EMR68213.1 - 4.8e-13 49.3 0.0 8e-13 48.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold GATase_4 PF13230.6 EMR68214.1 - 1.6e-14 53.5 0.0 1.7e-12 46.8 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EMR68214.1 - 9.8e-08 32.3 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain RTA1 PF04479.13 EMR68215.1 - 6e-55 186.1 12.0 7e-55 185.8 12.0 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.6 EMR68215.1 - 0.11 12.1 2.7 0.24 11.0 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Cation_efflux PF01545.21 EMR68216.1 - 2.5e-16 60.0 9.1 3.3e-16 59.6 9.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMR68216.1 - 1.3e-09 38.1 0.2 2.7e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter EspB PF05802.11 EMR68216.1 - 0.0016 18.5 1.4 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Enterobacterial EspB protein VirE_N PF08800.10 EMR68216.1 - 0.16 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 VirE N-terminal domain Ribosomal_L30 PF00327.20 EMR68216.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e Paf1 PF03985.13 EMR68219.1 - 5.1e-93 312.4 0.1 5.8e-93 312.2 0.1 1.0 1 0 0 1 1 1 1 Paf1 Rer1 PF03248.13 EMR68220.1 - 7.3e-79 263.4 2.5 8.5e-79 263.2 2.5 1.0 1 0 0 1 1 1 1 Rer1 family DLEU7 PF15760.5 EMR68221.1 - 4.3 6.8 10.8 9.3 5.7 4.1 2.6 1 1 1 2 2 2 0 Leukemia-associated protein 7 Aldo_ket_red PF00248.21 EMR68222.1 - 4.4e-60 203.4 0.0 4.9e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro2_C5 PF18565.1 EMR68223.1 - 1.1e-34 118.4 0.2 1.8e-34 117.7 0.2 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 DUF4982 PF16355.5 EMR68223.1 - 4.4e-26 90.6 0.1 8.2e-26 89.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Invasin_D3 PF09134.10 EMR68223.1 - 3.1e-07 30.6 1.8 6.9e-07 29.5 1.6 1.8 1 1 0 1 1 1 1 Invasin, domain 3 Big_1 PF02369.16 EMR68223.1 - 6.9e-06 26.0 2.8 1.9e-05 24.5 2.8 1.8 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) DUF824 PF05688.11 EMR68223.1 - 0.038 13.8 0.1 0.092 12.6 0.1 1.6 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) CarboxypepD_reg PF13620.6 EMR68223.1 - 0.4 11.0 4.8 6.1 7.2 0.5 3.2 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain DAHP_synth_1 PF00793.20 EMR68225.1 - 2.1e-105 351.5 0.1 2.4e-105 351.3 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MUG113 PF13455.6 EMR68225.1 - 0.1 13.3 0.0 0.32 11.7 0.0 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Ribosomal_L50 PF10501.9 EMR68226.1 - 8.6e-12 45.2 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S NUT PF12881.7 EMR68228.1 - 0.42 9.0 4.7 0.47 8.8 4.7 1.0 1 0 0 1 1 1 0 NUT protein SGL PF08450.12 EMR68229.1 - 0.0093 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Acyl-CoA_dh_1 PF00441.24 EMR68230.1 - 1.5e-27 96.7 2.0 1.6e-27 96.6 2.0 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 EMR68230.1 - 3.7e-12 46.7 0.6 4.2e-12 46.5 0.6 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AAA PF00004.29 EMR68231.1 - 5.5e-25 88.3 2.4 2.1e-13 50.8 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EMR68231.1 - 7.5e-13 48.5 0.0 7.5e-13 48.5 0.0 2.1 2 0 0 2 2 1 1 AAA lid domain AAA_22 PF13401.6 EMR68231.1 - 2.7e-09 37.4 0.5 0.89 9.8 0.1 4.6 4 0 0 4 4 4 3 AAA domain AAA_30 PF13604.6 EMR68231.1 - 1.6e-07 31.2 5.8 0.00048 19.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_5 PF07728.14 EMR68231.1 - 4e-07 30.1 1.4 0.04 13.9 0.1 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMR68231.1 - 6.4e-06 26.0 0.3 0.05 13.4 0.0 3.4 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EMR68231.1 - 3.5e-05 23.3 0.2 0.36 10.2 0.0 3.0 2 2 2 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EMR68231.1 - 0.00018 21.9 3.8 1.4 9.3 0.2 3.7 2 2 1 3 3 3 2 AAA domain Torsin PF06309.11 EMR68231.1 - 0.00028 21.0 0.1 3.9 7.6 0.0 3.4 2 1 0 3 3 3 2 Torsin RNA_helicase PF00910.22 EMR68231.1 - 0.0005 20.4 0.1 2.2 8.7 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Viral_helicase1 PF01443.18 EMR68231.1 - 0.001 18.8 0.0 1.9 8.2 0.0 2.8 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EMR68231.1 - 0.0019 18.1 0.6 0.88 9.5 0.1 3.0 2 0 0 2 2 2 1 NTPase IstB_IS21 PF01695.17 EMR68231.1 - 0.0037 17.0 0.0 2.4 7.8 0.0 2.7 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 EMR68231.1 - 0.012 15.1 0.0 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EMR68231.1 - 0.013 15.2 6.9 0.7 9.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EMR68231.1 - 0.056 13.6 0.0 0.056 13.6 0.0 3.7 3 1 0 3 3 2 0 AAA domain AAA_16 PF13191.6 EMR68231.1 - 0.075 13.4 4.4 5.4 7.4 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain DUF913 PF06025.12 EMR68231.1 - 0.23 10.4 5.8 0.44 9.5 5.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_18 PF13238.6 EMR68231.1 - 0.31 11.6 0.0 0.31 11.6 0.0 4.3 3 1 1 4 4 2 0 AAA domain AAA_28 PF13521.6 EMR68231.1 - 0.51 10.6 0.0 0.51 10.6 0.0 4.3 3 2 1 4 4 3 0 AAA domain AAA_11 PF13086.6 EMR68231.1 - 1.5 8.6 39.2 29 4.3 0.1 3.6 2 2 0 2 2 2 0 AAA domain CDC45 PF02724.14 EMR68231.1 - 1.5 7.0 30.6 2.2 6.5 30.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EMR68231.1 - 2 8.1 24.9 4.2 7.1 24.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SMP PF04927.12 EMR68233.1 - 5.8e-10 39.5 12.2 5e-07 30.1 3.6 2.1 1 1 1 2 2 2 2 Seed maturation protein Ifi-6-16 PF06140.13 EMR68233.1 - 0.061 13.3 0.6 3.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Interferon-induced 6-16 family NAD_binding_4 PF07993.12 EMR68234.1 - 2.3e-24 86.0 0.0 3.6e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EMR68234.1 - 1.5e-20 73.2 0.0 9.8e-20 70.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EMR68234.1 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Unstab_antitox PF09720.10 EMR68234.1 - 0.056 13.5 0.5 0.16 12.0 0.5 1.8 1 0 0 1 1 1 0 Putative addiction module component tRNA_synt_1c_R1 PF04558.15 EMR68235.1 - 0.25 11.3 0.2 0.38 10.8 0.2 1.2 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Dehydrin PF00257.19 EMR68236.1 - 0.0013 19.3 18.3 0.0084 16.7 18.3 2.2 1 1 0 1 1 1 1 Dehydrin Spt20 PF12090.8 EMR68236.1 - 1 8.9 16.4 0.013 15.1 4.6 2.2 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 EMR68236.1 - 7.3 6.1 19.1 0.43 10.2 14.0 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EI24 PF07264.11 EMR68237.1 - 4.8e-14 53.0 4.9 1e-13 51.9 4.9 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF302 PF03625.14 EMR68239.1 - 0.016 15.1 0.2 0.048 13.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF302 ADH_zinc_N_2 PF13602.6 EMR68240.1 - 1.4e-12 48.8 0.0 2.5e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR68240.1 - 9.3e-08 32.1 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR68240.1 - 7e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2781 PF10914.8 EMR68242.1 - 5.1e-38 130.8 5.0 6e-38 130.6 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Peptidase_S9 PF00326.21 EMR68242.1 - 0.085 12.3 0.1 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 EMR68243.1 - 4.1e-30 104.9 25.0 4.1e-30 104.9 25.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily GMC_oxred_N PF00732.19 EMR68244.1 - 1.7e-61 208.2 0.0 2.2e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR68244.1 - 1.7e-30 106.4 0.0 1.3e-29 103.6 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 EMR68244.1 - 2.7e-07 30.5 0.2 2.6e-06 27.3 0.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR68244.1 - 2.7e-06 27.5 0.1 1.6e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR68244.1 - 0.00017 20.9 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EMR68244.1 - 0.00019 20.8 0.2 0.26 10.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR68244.1 - 0.00067 18.8 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR68244.1 - 0.0015 17.7 0.0 0.025 13.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EMR68244.1 - 0.0052 15.5 0.0 0.011 14.5 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EMR68244.1 - 0.025 13.8 0.1 0.4 9.9 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR68244.1 - 0.17 11.9 0.4 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4387 PF14330.6 EMR68246.1 - 1.5e-29 102.6 0.0 2.6e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 EMR68246.1 - 6.7e-13 48.1 0.0 1.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MRI PF15325.6 EMR68246.1 - 5.6 8.1 6.5 12 7.0 6.5 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection adh_short PF00106.25 EMR68247.1 - 3e-35 121.4 0.0 4.2e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68247.1 - 7.4e-28 97.7 0.0 1.1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 EMR68247.1 - 6.3e-07 28.7 0.1 1.5e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EMR68247.1 - 1.5e-06 28.2 0.9 1.7e-05 24.8 0.9 2.2 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EMR68247.1 - 5.9e-05 23.3 0.1 0.00011 22.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EMR68247.1 - 6.7e-05 22.5 0.1 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR68247.1 - 0.0015 18.5 0.2 0.0032 17.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR68247.1 - 0.0047 16.5 0.7 0.066 12.8 0.8 2.1 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.20 EMR68247.1 - 0.027 14.6 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EMR68247.1 - 0.042 14.1 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_25 PF13649.6 EMR68247.1 - 0.048 14.4 0.1 0.092 13.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 EMR68247.1 - 0.05 13.5 0.5 0.05 13.5 0.5 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EMR68247.1 - 0.065 12.6 0.1 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMR68247.1 - 0.086 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LDcluster4 PF18306.1 EMR68247.1 - 0.11 12.1 1.3 0.14 11.8 0.4 1.6 2 0 0 2 2 2 0 SLOG cluster4 family ThiF PF00899.21 EMR68247.1 - 0.14 11.5 0.4 0.22 10.8 0.4 1.3 1 0 0 1 1 1 0 ThiF family Eno-Rase_NADH_b PF12242.8 EMR68247.1 - 0.38 10.6 2.2 4.1 7.2 0.4 2.5 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.22 EMR68248.1 - 1.2e-29 103.4 0.0 5.8e-29 101.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 BBE PF08031.12 EMR68249.1 - 4.7e-09 36.2 0.0 8.8e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EMR68249.1 - 1.6e-05 24.7 0.6 2.7e-05 23.9 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Porin_OmpL1 PF11389.8 EMR68249.1 - 0.036 13.3 0.1 0.058 12.6 0.1 1.2 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 DPBB_1 PF03330.18 EMR68252.1 - 1.9e-09 37.6 0.1 4.3e-09 36.5 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase zf-TFIIB PF13453.6 EMR68252.1 - 0.011 15.0 1.0 0.033 13.5 1.0 1.8 1 1 0 1 1 1 0 Transcription factor zinc-finger Metallophos PF00149.28 EMR68253.1 - 1.1e-37 130.6 0.1 1.9e-37 129.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase POTRA PF07244.15 EMR68253.1 - 0.027 15.0 0.0 0.088 13.4 0.0 1.9 2 0 0 2 2 2 0 Surface antigen variable number repeat p450 PF00067.22 EMR68254.1 - 2.9e-48 164.8 0.0 3.6e-47 161.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 adh_short_C2 PF13561.6 EMR68255.1 - 2e-59 201.0 0.9 5.7e-59 199.5 0.9 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR68255.1 - 6.7e-35 120.3 2.7 4.9e-34 117.5 2.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR68255.1 - 2.3e-07 30.9 0.3 1.1e-06 28.7 0.3 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMR68255.1 - 0.009 15.9 0.2 0.014 15.3 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMR68255.1 - 0.043 13.2 0.1 0.094 12.1 0.1 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LPD29 PF18847.1 EMR68255.1 - 0.052 14.5 0.1 0.18 12.7 0.1 2.0 1 1 0 1 1 1 0 Large polyvalent protein associated domain 29 Toprim PF01751.22 EMR68255.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Toprim domain TauD PF02668.16 EMR68256.1 - 5.7e-34 118.1 0.0 7.4e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EMR68256.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 CsiD Kinesin PF00225.23 EMR68257.1 - 8.4e-54 182.7 0.0 1.2e-53 182.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMR68257.1 - 1.2e-10 41.6 0.0 2.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Ribosomal_60s PF00428.19 EMR68257.1 - 1.6 9.4 4.5 4.6 7.9 0.2 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4337 PF14235.6 EMR68258.1 - 0.14 12.2 2.2 0.36 10.9 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) KBP_C PF12309.8 EMR68258.1 - 0.2 11.2 2.2 0.24 10.9 2.2 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal FPP PF05911.11 EMR68259.1 - 0.00082 17.7 25.1 0.0011 17.3 25.1 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil HOOK PF05622.12 EMR68259.1 - 0.0016 16.7 36.9 0.0022 16.2 36.9 1.1 1 0 0 1 1 1 1 HOOK protein ERM PF00769.19 EMR68259.1 - 0.0017 18.2 23.4 0.0017 18.2 23.4 2.3 1 1 1 2 2 1 1 Ezrin/radixin/moesin family Lebercilin PF15619.6 EMR68259.1 - 0.0053 16.4 20.7 0.0053 16.4 20.7 2.7 1 1 1 2 2 1 1 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 EMR68259.1 - 0.037 14.6 41.8 0.046 14.2 20.5 3.2 1 1 0 2 2 2 0 Apg6 coiled-coil region KxDL PF10241.9 EMR68259.1 - 0.17 12.1 13.8 2.9 8.3 0.2 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.7 EMR68259.1 - 0.18 12.0 42.5 0.03 14.5 25.9 3.5 1 1 2 3 3 3 0 Tropomyosin like Laminin_II PF06009.12 EMR68259.1 - 0.31 11.1 15.8 0.09 12.8 6.7 2.9 1 1 1 2 2 2 0 Laminin Domain II Sec20 PF03908.13 EMR68259.1 - 0.43 10.5 2.5 1.2 9.1 1.0 2.5 1 1 1 2 2 2 0 Sec20 KASH_CCD PF14662.6 EMR68259.1 - 0.52 10.1 31.8 0.1 12.4 16.9 2.9 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 EMR68259.1 - 0.55 9.6 38.8 1.5 8.3 16.1 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Tropomyosin PF00261.20 EMR68259.1 - 0.68 9.3 46.0 64 2.8 10.0 2.5 1 1 1 2 2 2 0 Tropomyosin Bacillus_HBL PF05791.11 EMR68259.1 - 1.2 8.9 11.1 0.22 11.3 7.2 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.9 EMR68259.1 - 1.7 9.0 18.2 1.7 9.0 0.6 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 EMR68259.1 - 1.9 8.3 40.2 0.63 9.8 2.0 5.0 2 1 3 5 5 5 0 Phage minor structural protein GP20 DUF724 PF05266.14 EMR68259.1 - 2.6 7.8 35.9 0.022 14.6 11.3 3.4 1 1 2 3 3 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EMR68259.1 - 3.6 7.6 44.1 0.037 14.1 1.7 3.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 EMR68259.1 - 3.6 6.8 36.5 0.036 13.4 11.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) AAA_13 PF13166.6 EMR68259.1 - 5.6 5.5 30.7 15 4.0 30.6 1.7 1 1 0 1 1 1 0 AAA domain DUF1043 PF06295.12 EMR68259.1 - 7.9 6.5 10.1 6 6.9 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) CorA PF01544.18 EMR68260.1 - 1.8e-08 34.1 0.2 3.6e-08 33.1 0.1 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2232 PF09991.9 EMR68260.1 - 0.0055 15.9 0.5 0.0077 15.4 0.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) DUF5082 PF16888.5 EMR68260.1 - 0.08 13.2 0.9 0.14 12.5 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Glyco_transf_18 PF15024.6 EMR68260.1 - 0.087 11.4 0.1 0.09 11.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 Clc-like PF07062.12 EMR68260.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Clc-like DUF2058 PF09831.9 EMR68260.1 - 0.11 12.7 1.1 0.16 12.1 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Pec_lyase_C PF00544.19 EMR68262.1 - 8e-37 126.9 5.7 1.1e-36 126.4 5.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EMR68262.1 - 4.8e-05 23.3 8.5 1.5 8.6 1.7 2.2 1 1 0 1 1 1 1 Right handed beta helix region SRP9-21 PF05486.12 EMR68263.1 - 0.21 12.0 4.2 1.2 9.5 0.3 2.5 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) RIC3 PF15361.6 EMR68263.1 - 3 8.2 11.0 5.2 7.4 0.4 2.6 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 ADH_zinc_N PF00107.26 EMR68265.1 - 8.3e-26 90.5 0.6 1.3e-25 89.8 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR68265.1 - 8.2e-22 77.2 0.7 8.2e-22 77.2 0.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMR68265.1 - 8.9e-07 30.0 0.0 1.7e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LDcluster4 PF18306.1 EMR68265.1 - 0.011 15.3 1.6 0.011 15.3 1.6 1.6 2 0 0 2 2 2 0 SLOG cluster4 family adh_short PF00106.25 EMR68265.1 - 0.028 13.9 1.0 0.051 13.0 0.7 1.5 1 1 0 1 1 1 0 short chain dehydrogenase SnoaL PF07366.12 EMR68266.1 - 0.13 12.1 0.8 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase TYW3 PF02676.14 EMR68267.1 - 0.00094 18.6 1.5 0.0011 18.3 0.3 1.8 2 0 0 2 2 2 1 Methyltransferase TYW3 HSBP1 PF06825.12 EMR68267.1 - 0.19 11.6 5.0 11 6.0 0.2 5.4 6 0 0 6 6 6 0 Heat shock factor binding protein 1 Rab5-bind PF09311.11 EMR68267.1 - 0.54 9.6 33.2 1.7 8.0 16.3 4.1 2 1 2 4 4 4 0 Rabaptin-like protein NPV_P10 PF05531.12 EMR68267.1 - 2.9 8.4 26.5 2.8 8.5 0.2 6.8 2 1 4 6 6 6 0 Nucleopolyhedrovirus P10 protein YccV-like PF08755.11 EMR68268.1 - 5.9e-27 94.1 0.0 1.1e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EMR68268.1 - 8.4e-10 38.4 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 EMR68268.1 - 2.3e-05 24.2 0.4 6.1e-05 22.8 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR68268.1 - 0.00091 19.0 0.1 0.002 17.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain Peptidase_C54 PF03416.19 EMR68268.1 - 0.026 13.9 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C54 Acetyltransf_1 PF00583.25 EMR68269.1 - 9.1e-14 51.7 0.0 1.3e-13 51.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR68269.1 - 4.3e-08 33.5 0.0 7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR68269.1 - 5.2e-08 32.9 0.0 8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR68269.1 - 3.3e-05 24.0 0.0 6.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR68269.1 - 0.00012 22.0 0.0 0.00036 20.4 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 EMR68269.1 - 0.018 15.7 0.0 0.022 15.4 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EMR68271.1 - 1.9e-15 56.7 31.1 1.9e-15 56.7 31.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR68271.1 - 2.8e-12 46.6 7.6 2.8e-12 46.6 7.6 3.2 4 1 0 4 4 4 1 Ion channel regulatory protein UNC-93 7TM_GPCR_Sri PF10327.9 EMR68271.1 - 0.38 9.9 4.6 0.79 8.8 4.6 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Caldesmon PF02029.15 EMR68272.1 - 0.00063 18.6 21.6 0.0008 18.3 21.6 1.1 1 0 0 1 1 1 1 Caldesmon TFIIF_alpha PF05793.12 EMR68272.1 - 0.0015 17.2 30.8 0.0021 16.8 30.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EMR68272.1 - 0.0047 15.2 31.8 0.0064 14.8 31.8 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 EMR68272.1 - 0.012 14.9 29.5 0.017 14.5 29.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EMR68272.1 - 0.08 12.4 32.3 0.12 11.8 32.3 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EMR68272.1 - 0.14 10.5 25.4 0.19 10.0 25.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 EMR68272.1 - 0.19 12.0 15.4 0.39 11.0 15.4 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 EMR68272.1 - 0.58 9.1 31.6 0.83 8.6 31.6 1.1 1 0 0 1 1 1 0 Paf1 SpoIIIAH PF12685.7 EMR68272.1 - 0.59 9.9 13.9 0.9 9.3 13.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein NPR3 PF03666.13 EMR68272.1 - 0.6 8.8 17.0 0.83 8.4 17.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 EMR68272.1 - 0.7 8.8 8.5 1.1 8.2 8.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mpp10 PF04006.12 EMR68272.1 - 0.79 8.1 35.7 1.2 7.5 35.7 1.2 1 0 0 1 1 1 0 Mpp10 protein Cwf_Cwc_15 PF04889.12 EMR68272.1 - 0.89 9.2 30.6 2 8.1 30.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Merozoite_SPAM PF07133.11 EMR68272.1 - 0.92 9.5 46.9 1.7 8.6 46.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF3306 PF11748.8 EMR68272.1 - 0.99 10.3 15.5 2.5 9.0 15.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Peptidase_S64 PF08192.11 EMR68272.1 - 1.1 7.7 6.1 1.4 7.4 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DDHD PF02862.17 EMR68272.1 - 1.2 9.2 3.2 1.7 8.8 3.2 1.2 1 0 0 1 1 1 0 DDHD domain IFT57 PF10498.9 EMR68272.1 - 1.8 7.4 16.6 2.7 6.8 16.6 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RR_TM4-6 PF06459.12 EMR68272.1 - 2 8.2 18.6 3 7.6 18.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Drc1-Sld2 PF11719.8 EMR68272.1 - 3.3 7.1 23.3 4.8 6.6 23.3 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein CCSAP PF15748.5 EMR68272.1 - 3.6 7.7 18.9 5.8 7.0 18.9 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MCM_bind PF09739.9 EMR68272.1 - 3.8 5.8 12.1 5.2 5.4 12.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor ORC6 PF05460.13 EMR68272.1 - 5.5 6.2 11.8 7.5 5.7 11.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hid1 PF12722.7 EMR68272.1 - 5.8 4.9 13.3 9 4.3 12.7 1.5 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein SpoIIP PF07454.11 EMR68272.1 - 6.6 6.1 15.3 10 5.5 15.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DNA_pol_phi PF04931.13 EMR68272.1 - 7.9 4.4 47.9 12 3.9 47.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi MDM1 PF15501.6 EMR68272.1 - 9.3 5.3 25.9 12 4.9 25.9 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 FAM60A PF15396.6 EMR68272.1 - 9.4 6.2 7.7 14 5.6 7.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 EMR68272.1 - 9.8 4.8 16.3 13 4.4 16.3 1.1 1 0 0 1 1 1 0 Presenilin Spc7 PF08317.11 EMR68273.1 - 0.056 12.3 4.5 0.089 11.7 4.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3213 PF11491.8 EMR68273.1 - 0.073 13.3 0.1 40 4.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3213) Hen1_L PF12623.7 EMR68273.1 - 0.11 11.5 0.3 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 DUF4407 PF14362.6 EMR68273.1 - 0.17 11.2 1.9 0.27 10.5 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LTXXQ PF07813.12 EMR68273.1 - 0.44 11.3 6.1 3 8.6 4.1 2.2 2 0 0 2 2 2 0 LTXXQ motif family protein DUF4404 PF14357.6 EMR68273.1 - 0.68 10.6 4.3 8.8 7.1 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) RasGEF PF00617.19 EMR68274.1 - 6.8e-52 176.2 0.0 1.3e-51 175.3 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EMR68274.1 - 5.5e-18 65.1 0.0 3.1e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif Glyco_hydro_63 PF03200.16 EMR68276.1 - 8.1e-149 496.5 0.0 1.5e-147 492.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EMR68276.1 - 5.1e-47 160.9 0.0 9.4e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EMR68276.1 - 0.0017 17.2 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 EMR68276.1 - 0.0067 15.4 0.0 0.015 14.3 0.0 1.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase FlaE PF07559.14 EMR68276.1 - 0.073 13.7 0.3 0.14 12.8 0.3 1.5 1 0 0 1 1 1 0 Flagellar basal body protein FlaE FoP_duplication PF13865.6 EMR68277.1 - 0.0027 18.2 27.4 0.0068 16.9 21.8 3.1 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Metallophos PF00149.28 EMR68278.1 - 8.2e-17 62.4 0.0 2.1e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EMR68278.1 - 5.9e-14 52.7 1.1 1.4e-13 51.5 0.1 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EMR68278.1 - 1.4e-10 41.6 0.8 2.7e-10 40.7 0.8 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EMR68278.1 - 0.00051 20.5 0.1 0.0066 17.0 0.1 2.3 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Peptidase_S8 PF00082.22 EMR68279.1 - 2.7e-19 69.5 0.5 5.8e-19 68.5 0.5 1.5 1 1 0 1 1 1 1 Subtilase family Sacchrp_dh_NADP PF03435.18 EMR68280.1 - 2e-17 63.6 0.1 3.1e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMR68280.1 - 0.0027 17.8 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 EMR68280.1 - 0.014 15.9 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EMR68280.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Tyrosinase PF00264.20 EMR68281.1 - 6.6e-53 180.3 1.9 1e-52 179.7 1.9 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Ammonium_transp PF00909.21 EMR68283.1 - 4.4e-117 391.2 29.2 5e-117 391.0 29.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family AA_permease PF00324.21 EMR68284.1 - 4e-126 421.4 28.1 4.5e-126 421.3 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR68284.1 - 8.3e-32 110.5 30.7 1e-31 110.2 30.7 1.1 1 0 0 1 1 1 1 Amino acid permease Rer1 PF03248.13 EMR68284.1 - 0.47 10.2 2.3 0.5 10.1 0.2 2.2 2 0 0 2 2 2 0 Rer1 family Cyclin_C_2 PF16899.5 EMR68285.1 - 1.4e-33 115.3 0.0 1.5e-31 108.9 0.0 2.4 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 EMR68285.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMR68285.1 - 0.014 15.5 0.1 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Glyco_hydro_43 PF04616.14 EMR68286.1 - 2.9e-99 332.0 0.2 4.9e-99 331.3 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EMR68286.1 - 6.2e-47 159.9 0.0 8.4e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 EMR68286.1 - 0.042 13.4 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain AA_permease PF00324.21 EMR68287.1 - 4.3e-102 342.2 40.8 5e-102 341.9 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR68287.1 - 7.3e-28 97.5 43.1 8.6e-28 97.3 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3597 PF12200.8 EMR68288.1 - 0.93 10.0 5.9 0.31 11.6 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Dicty_REP PF05086.12 EMR68288.1 - 6.2 4.7 6.2 0.32 8.9 1.3 1.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein FAD_binding_4 PF01565.23 EMR68289.1 - 1.3e-16 60.6 0.2 2.4e-16 59.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR68289.1 - 6.8e-10 38.9 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Y_phosphatase3 PF13350.6 EMR68290.1 - 2e-55 188.3 0.0 2.3e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EMR68290.1 - 6.8e-05 22.6 0.0 0.00016 21.3 0.0 1.5 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EMR68290.1 - 0.012 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.14 EMR68290.1 - 0.027 13.4 0.0 0.063 12.2 0.0 1.5 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 EMR68290.1 - 0.032 14.1 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain ThuA PF06283.11 EMR68291.1 - 1.4e-74 250.9 0.0 1.5e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF4159 PF13709.6 EMR68291.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Fungal_trans_2 PF11951.8 EMR68293.1 - 1.7e-34 119.3 1.7 2.3e-34 118.8 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR68293.1 - 9.9e-07 28.8 7.7 1.9e-06 27.9 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DCP1 PF06058.13 EMR68294.1 - 1.4e-30 105.6 0.0 1.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family SwrA PF17423.2 EMR68294.1 - 0.14 12.2 0.2 0.72 9.8 0.0 1.9 2 0 0 2 2 2 0 Swarming motility protein BAR PF03114.18 EMR68295.1 - 9.3e-49 166.2 6.0 1.1e-48 165.9 6.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EMR68295.1 - 4.5e-06 26.0 2.9 7.5e-06 25.3 2.9 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking RsmJ PF04378.13 EMR68295.1 - 0.037 13.2 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ FAM184 PF15665.5 EMR68295.1 - 5.2 6.8 11.8 3.2 7.5 4.8 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B UPF0242 PF06785.11 EMR68295.1 - 9.9 6.2 8.6 1.2 9.2 3.6 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Exo_endo_phos PF03372.23 EMR68296.1 - 2e-05 24.2 0.0 5.6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BCNT PF07572.12 EMR68296.1 - 0.14 12.2 0.7 0.33 11.0 0.7 1.5 1 0 0 1 1 1 0 Bucentaur or craniofacial development DIOX_N PF14226.6 EMR68297.1 - 0.00064 20.5 0.0 0.002 18.9 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal NAAA-beta PF15508.6 EMR68297.1 - 0.07 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase NAD_binding_4 PF07993.12 EMR68298.1 - 1.3e-25 90.1 0.0 2.1e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EMR68298.1 - 5e-08 32.7 0.0 4.7e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR68298.1 - 0.001 19.4 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 EMR68298.1 - 0.027 14.9 0.0 0.057 13.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EMR68298.1 - 0.089 12.2 0.0 6.1 6.1 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PIG-P PF08510.12 EMR68299.1 - 2.8e-54 182.2 5.0 3.6e-54 181.8 5.0 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 EMR68299.1 - 0.093 12.8 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DPM2 PF07297.12 EMR68299.1 - 0.26 11.6 10.9 0.47 10.8 10.9 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Rab5ip PF07019.12 EMR68299.1 - 0.43 11.2 4.8 0.59 10.8 4.2 1.5 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF485 PF04341.12 EMR68299.1 - 9.8 6.2 8.0 0.51 10.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Actin PF00022.19 EMR68300.1 - 1.4e-145 485.0 0.0 1.7e-145 484.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EMR68300.1 - 1.5e-10 40.4 0.2 0.00062 18.7 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein RisS_PPD PF16524.5 EMR68300.1 - 0.054 13.7 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS Aldo_ket_red PF00248.21 EMR68301.1 - 2.5e-70 237.0 0.0 3e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Helitron_like_N PF14214.6 EMR68302.1 - 5.1e-57 193.2 0.1 9e-57 192.4 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EMR68302.1 - 6.7e-28 97.9 0.0 1e-27 97.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EMR68302.1 - 4.1e-05 23.4 0.0 6.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EMR68302.1 - 0.00098 19.2 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Inovirus_Gp2 PF11726.8 EMR68302.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Inovirus Gp2 AAA_16 PF13191.6 EMR68302.1 - 0.083 13.3 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Enolase_C PF00113.22 EMR68303.1 - 5.4e-152 505.2 0.2 7.1e-152 504.8 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EMR68303.1 - 1.5e-57 193.4 0.2 3e-57 192.4 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EMR68303.1 - 9.3e-06 25.4 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EMR68303.1 - 0.029 13.5 0.5 0.54 9.4 0.2 2.6 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus DUF5532 PF17673.1 EMR68304.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5532) VRR_NUC PF08774.11 EMR68306.1 - 3.9e-25 88.0 0.0 6.5e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 VRR-NUC domain DUF1275 PF06912.11 EMR68308.1 - 3.3e-35 121.8 10.1 4.1e-35 121.5 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Hydrolase_like PF13242.6 EMR68308.1 - 0.06 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like LRR_8 PF13855.6 EMR68309.1 - 1.8e-11 43.7 3.9 3.4e-05 23.5 3.3 4.1 3 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EMR68309.1 - 6.2e-09 36.0 5.4 0.035 14.5 1.6 4.3 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMR68309.1 - 2.8e-06 26.9 3.8 6.5 7.1 0.0 5.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 EMR68309.1 - 3.1e-05 23.5 0.7 2 7.9 0.0 4.1 2 1 1 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 EMR68309.1 - 0.022 15.2 2.3 2.4e+02 2.9 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat FMN_dh PF01070.18 EMR68310.1 - 2.8e-107 358.8 0.0 3.4e-107 358.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EMR68310.1 - 8.8e-19 67.4 0.0 1.8e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EMR68310.1 - 6.6e-07 28.8 1.0 8.2e-07 28.5 0.1 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 EMR68310.1 - 1.7e-05 24.0 0.0 4.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.11 EMR68310.1 - 0.04 13.7 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein His_biosynth PF00977.21 EMR68310.1 - 0.045 13.2 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 EMR68310.1 - 0.082 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 EMR68310.1 - 0.17 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Ribosomal_S13_N PF08069.12 EMR68311.1 - 1.4e-29 101.9 0.0 2.5e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EMR68311.1 - 4e-15 55.8 0.2 6.3e-15 55.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EMR68311.1 - 0.1 12.6 0.1 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain MaoC_dehydratas PF01575.19 EMR68312.1 - 1.2e-21 76.6 0.0 1.9e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain ERp29_N PF07912.13 EMR68312.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 ERp29, N-terminal domain Dpy-30 PF05186.13 EMR68313.1 - 5.8e-15 54.7 0.1 7.8e-15 54.3 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif BSP_II PF05432.11 EMR68314.1 - 0.054 13.2 11.8 0.092 12.4 11.8 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF977 PF06163.11 EMR68314.1 - 0.11 12.5 0.8 0.26 11.2 0.8 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Sclerostin PF05463.11 EMR68314.1 - 0.28 10.9 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Sclerostin (SOST) SMK-1 PF04802.15 EMR68316.1 - 0.029 14.2 0.5 0.049 13.5 0.5 1.3 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 Dicistro_VP4 PF11492.8 EMR68317.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 PX PF00787.24 EMR68319.1 - 1.6e-21 76.4 0.0 2.6e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 PX domain Mpv17_PMP22 PF04117.12 EMR68320.1 - 1.5e-21 76.4 0.6 2.4e-21 75.7 0.6 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family SGL PF08450.12 EMR68321.1 - 0.0033 17.0 0.1 2.9 7.4 0.0 2.3 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region bMG6 PF17962.1 EMR68321.1 - 0.11 12.7 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 Noc2 PF03715.13 EMR68322.1 - 3.4e-130 433.7 0.0 8.1e-130 432.4 0.0 1.7 1 0 0 1 1 1 1 Noc2p family Hid1 PF12722.7 EMR68322.1 - 2.2 6.3 8.5 3.3 5.7 8.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_M16 PF00675.20 EMR68323.1 - 8.4e-57 191.3 0.1 1.2e-55 187.6 0.1 2.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMR68323.1 - 8.7e-37 126.9 0.0 4.6e-36 124.5 0.0 2.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain Esterase PF00756.20 EMR68323.1 - 0.045 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase IU_nuc_hydro PF01156.19 EMR68325.1 - 8.7e-61 206.1 0.1 1e-60 205.9 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Helo_like_N PF17111.5 EMR68326.1 - 3.1e-08 33.2 0.0 3.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Sugar_tr PF00083.24 EMR68327.1 - 4.1e-104 349.0 24.6 4.8e-104 348.7 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR68327.1 - 1.9e-26 92.8 45.4 1.1e-22 80.4 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4387 PF14330.6 EMR68328.1 - 5e-32 110.5 0.1 1.6e-31 108.9 0.0 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4387) AtuA PF07287.11 EMR68328.1 - 5.4e-20 71.4 0.0 8.8e-19 67.4 0.0 2.4 2 1 0 2 2 2 1 Acyclic terpene utilisation family protein AtuA zf-RING_7 PF02591.15 EMR68329.1 - 0.031 14.5 0.4 18 5.6 0.0 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain Gamma-thionin PF00304.20 EMR68329.1 - 0.31 11.3 12.5 0.75 10.1 0.4 3.8 3 2 0 3 3 3 0 Gamma-thionin family Sugar_tr PF00083.24 EMR68330.1 - 2.6e-40 138.7 15.1 1.4e-39 136.3 14.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR68330.1 - 9.1e-11 41.3 15.8 1.3e-10 40.8 15.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DNA_pol_A_exo1 PF01612.20 EMR68331.1 - 0.0025 17.5 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PhyH PF05721.13 EMR68332.1 - 2.4e-09 37.7 0.0 8.4e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Epimerase PF01370.21 EMR68333.1 - 3.3e-10 39.8 0.1 2.8e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR68333.1 - 2.8e-09 37.1 0.1 5.2e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EMR68333.1 - 1.5e-06 28.6 0.0 3.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMR68333.1 - 1.5e-05 24.1 0.0 0.058 12.4 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EMR68333.1 - 0.00093 18.8 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EMR68333.1 - 0.0082 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EMR68333.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain VPS28 PF03997.12 EMR68334.1 - 8.6e-68 227.7 0.1 1e-67 227.5 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Tam41_Mmp37 PF09139.11 EMR68335.1 - 1.2e-127 425.8 0.0 1.5e-127 425.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF3455 PF11937.8 EMR68336.1 - 0.042 14.2 0.1 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3455) Glyco_hydro_64 PF16483.5 EMR68337.1 - 5.5e-121 404.3 0.0 6.4e-121 404.1 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase p450 PF00067.22 EMR68338.1 - 5.9e-50 170.4 0.0 8.6e-44 150.0 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 muHD PF10291.9 EMR68339.1 - 1.4e-59 201.7 0.0 3.4e-59 200.4 0.0 1.6 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EMR68339.1 - 1.2e-07 31.9 0.5 1.2e-07 31.9 0.5 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5130 PF17174.4 EMR68339.1 - 0.012 15.9 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) BAR_3 PF16746.5 EMR68339.1 - 0.018 14.7 3.1 0.029 14.1 3.1 1.2 1 0 0 1 1 1 0 BAR domain of APPL family V_ATPase_I PF01496.19 EMR68339.1 - 0.062 11.2 1.7 0.084 10.8 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lipoprotein_2 PF00921.17 EMR68339.1 - 0.64 9.5 3.5 0.79 9.2 0.1 2.3 2 0 0 2 2 2 0 Borrelia lipoprotein Vps5 PF09325.10 EMR68339.1 - 1.6 8.2 8.5 0.11 12.0 0.7 2.5 3 0 0 3 3 3 0 Vps5 C terminal like SOAR PF16533.5 EMR68339.1 - 2.6 8.1 6.9 17 5.4 2.2 2.9 1 1 1 2 2 2 0 STIM1 Orai1-activating region Cullin PF00888.22 EMR68340.1 - 1.5e-127 426.9 0.2 2.4e-127 426.1 0.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EMR68340.1 - 1.8e-25 88.7 3.8 3.6e-24 84.6 3.0 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain SapB_1 PF05184.15 EMR68340.1 - 0.027 14.5 0.5 2.2 8.4 0.3 2.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 baeRF_family7 PF18849.1 EMR68340.1 - 0.028 14.6 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 MAD PF05557.13 EMR68342.1 - 1.3e-64 218.8 61.4 2.4e-63 214.6 61.2 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein Apq12 PF12716.7 EMR68343.1 - 1.4e-08 34.5 15.8 3.1e-08 33.5 15.8 1.6 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis VirB8 PF04335.13 EMR68343.1 - 0.32 10.8 6.2 0.11 12.4 3.1 1.7 1 1 1 2 2 2 0 VirB8 protein adh_short PF00106.25 EMR68344.1 - 2.5e-21 76.1 0.0 1.6e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68344.1 - 2.1e-07 30.7 0.0 9.2e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68344.1 - 0.00055 19.9 0.1 0.0009 19.2 0.1 1.2 1 0 0 1 1 1 1 KR domain ATP_bind_1 PF03029.17 EMR68345.1 - 1e-72 244.8 0.0 5.9e-72 242.3 0.0 1.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EMR68345.1 - 0.0009 19.1 0.0 0.0025 17.7 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EMR68345.1 - 0.0013 18.8 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMR68345.1 - 0.0039 17.6 0.0 0.0074 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EMR68345.1 - 0.0039 17.7 0.0 0.018 15.5 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 EMR68345.1 - 0.0052 16.5 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EMR68345.1 - 0.0077 15.9 0.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase RsgA_GTPase PF03193.16 EMR68345.1 - 0.0094 15.9 0.1 0.35 10.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase CbiA PF01656.23 EMR68345.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EMR68345.1 - 0.02 15.1 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EMR68345.1 - 0.026 14.9 0.3 1 9.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EMR68345.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EMR68345.1 - 0.029 14.9 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EMR68345.1 - 0.03 14.5 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR68345.1 - 0.035 14.5 0.3 0.24 11.8 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EMR68345.1 - 0.036 14.1 0.0 0.19 11.8 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 EMR68345.1 - 0.038 13.3 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Septin TRADD_N PF09034.10 EMR68345.1 - 0.042 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain Cytidylate_kin PF02224.18 EMR68345.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 EMR68345.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 EMR68345.1 - 0.086 12.4 0.0 5.4 6.5 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain SRP54 PF00448.22 EMR68345.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 EMR68345.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EMR68345.1 - 0.15 12.1 0.0 6.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 EMR68345.1 - 0.15 11.8 0.0 0.87 9.3 0.0 2.1 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EMR68345.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Oxidored_FMN PF00724.20 EMR68346.1 - 3.2e-49 168.0 0.0 6.2e-37 127.6 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EMR68346.1 - 9.6e-07 28.2 0.0 1.2e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF1611_N PF17396.2 EMR68346.1 - 0.022 15.0 0.0 0.071 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain His_biosynth PF00977.21 EMR68346.1 - 0.047 13.2 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Pinin_SDK_N PF04697.13 EMR68347.1 - 0.22 12.2 0.0 0.22 12.2 0.0 2.2 3 0 0 3 3 3 0 pinin/SDK conserved region S-AdoMet_synt_C PF02773.16 EMR68348.1 - 8.8e-65 216.9 0.0 1.8e-64 215.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 EMR68348.1 - 4.2e-43 146.1 0.1 9.2e-43 145.0 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EMR68348.1 - 6.9e-42 142.5 0.0 1.3e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 EMR68348.1 - 0.049 12.4 0.2 0.13 11.0 0.1 1.7 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) IU_nuc_hydro PF01156.19 EMR68349.1 - 5.7e-08 32.7 0.0 7.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Sulfotransfer_4 PF17784.1 EMR68350.1 - 2.4e-48 164.8 0.0 2.8e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR68350.1 - 0.015 15.6 0.1 0.49 10.8 0.0 2.2 1 1 0 2 2 2 0 Sulfotransferase family COX5A PF02284.16 EMR68352.1 - 9.9e-41 137.9 0.2 1.2e-40 137.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va 6PGD PF00393.19 EMR68353.1 - 3.9e-86 289.0 0.0 4.8e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EMR68353.1 - 5.2e-31 107.9 0.0 9.5e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EMR68353.1 - 2.1e-05 24.2 0.0 4.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EMR68353.1 - 3.8e-05 23.1 0.0 7.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMR68353.1 - 7e-05 22.8 0.1 0.0002 21.3 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EMR68353.1 - 0.0077 16.2 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EMR68353.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EMR68353.1 - 0.062 13.9 0.0 0.23 12.0 0.0 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 EMR68353.1 - 0.12 12.7 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF4201 PF13870.6 EMR68354.1 - 0.0029 17.3 22.5 0.0039 17.0 12.1 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) SCP-1 PF05483.12 EMR68354.1 - 0.0036 15.4 5.1 0.0036 15.4 5.1 2.7 1 1 2 3 3 3 1 Synaptonemal complex protein 1 (SCP-1) CENP-F_leu_zip PF10473.9 EMR68354.1 - 0.053 13.6 30.1 0.6 10.1 12.9 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lipoprotein_7 PF01540.16 EMR68354.1 - 0.081 12.2 7.0 0.11 11.8 5.5 2.1 1 1 0 1 1 1 0 Adhesin lipoprotein ERM PF00769.19 EMR68354.1 - 0.15 11.9 38.0 0.23 11.3 12.4 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3584 PF12128.8 EMR68354.1 - 0.24 8.9 28.5 0.73 7.3 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) YabA PF06156.13 EMR68354.1 - 0.52 11.0 19.0 0.59 10.8 3.7 3.7 1 1 3 4 4 4 0 Initiation control protein YabA EzrA PF06160.12 EMR68354.1 - 0.56 8.3 15.6 0.17 10.1 10.8 2.0 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF2730 PF10805.8 EMR68354.1 - 0.63 10.2 10.3 2 8.5 1.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) ATG16 PF08614.11 EMR68354.1 - 1.5 9.0 38.1 0.36 11.0 10.2 3.8 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) NYD-SP28_assoc PF14775.6 EMR68354.1 - 2.1 8.5 9.3 7.6 6.7 0.8 3.8 3 1 1 4 4 4 0 Sperm tail C-terminal domain Laminin_II PF06009.12 EMR68354.1 - 2.2 8.3 13.9 1.2 9.2 2.9 3.2 1 1 1 2 2 2 0 Laminin Domain II Bcr-Abl_Oligo PF09036.10 EMR68354.1 - 2.7 8.1 10.5 4.2 7.4 0.2 3.8 3 1 1 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain UPF0242 PF06785.11 EMR68354.1 - 5 7.2 23.1 1.2 9.3 8.6 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 EMR68354.1 - 5.6 6.3 26.0 4.4 6.7 10.5 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Phage_GP20 PF06810.11 EMR68354.1 - 7.2 6.4 12.9 1.1 9.1 5.5 2.9 1 1 3 4 4 4 0 Phage minor structural protein GP20 GAS PF13851.6 EMR68354.1 - 9.9 5.5 25.4 0.11 11.8 11.6 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ELO PF01151.18 EMR68355.1 - 3.4e-62 210.2 16.7 4.2e-62 209.9 16.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1772 PF08592.11 EMR68356.1 - 1.6e-18 67.4 1.1 1.8e-18 67.2 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Nodulin_late PF07127.11 EMR68357.1 - 0.086 13.2 0.3 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 Late nodulin protein PGG PF13962.6 EMR68357.1 - 0.23 11.3 1.6 0.3 10.9 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function Phage_Mu_Gam PF07352.12 EMR68358.1 - 0.035 14.0 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein AMP-binding PF00501.28 EMR68359.1 - 1.7e-14 53.2 0.4 3.3e-14 52.3 0.2 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR68359.1 - 1.4e-09 38.8 0.0 2.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HSF_DNA-bind PF00447.17 EMR68360.1 - 2.7e-12 47.1 1.7 3.7e-12 46.7 1.7 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding RT_RNaseH_2 PF17919.1 EMR68361.1 - 6.4e-21 74.3 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EMR68361.1 - 8.6e-18 64.6 0.0 1.8e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EMR68361.1 - 2.5e-15 56.3 0.1 4.9e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EMR68361.1 - 3e-05 24.2 0.0 8.8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 EMR68361.1 - 0.00043 20.5 0.1 0.0022 18.2 0.1 2.3 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 EMR68361.1 - 0.00097 18.7 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SURF2 PF05477.11 EMR68361.1 - 0.2 11.3 0.2 0.37 10.5 0.2 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RVP PF00077.20 EMR68362.1 - 0.00045 20.5 0.0 0.00094 19.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EMR68362.1 - 0.0022 18.5 0.0 0.0073 16.9 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EMR68362.1 - 0.0043 17.7 0.0 0.01 16.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Cbl_N PF02262.16 EMR68362.1 - 0.048 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 HTH_29 PF13551.6 EMR68362.1 - 0.46 10.5 2.2 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix zf-C2H2 PF00096.26 EMR68363.1 - 5.5e-06 26.5 11.7 1.4e-05 25.2 3.8 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMR68363.1 - 1.4e-05 25.3 6.9 3.1e-05 24.2 3.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMR68363.1 - 3.2e-05 24.4 2.3 3.2e-05 24.4 2.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMR68363.1 - 0.0012 19.1 1.0 0.0012 19.1 1.0 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EMR68363.1 - 0.0014 18.6 1.8 0.0014 18.6 1.8 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 EMR68363.1 - 0.17 12.3 2.0 0.27 11.7 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 EMR68363.1 - 0.25 11.8 1.4 0.5 10.9 1.4 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 EMR68363.1 - 0.46 10.8 2.5 0.77 10.1 0.7 2.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.13 EMR68363.1 - 5.1 7.4 12.0 0.096 13.0 4.1 2.1 3 0 0 3 3 3 0 Arsenite-resistance protein 2 zf-H2C2_5 PF13909.6 EMR68363.1 - 8.8 6.2 9.4 0.81 9.5 2.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF4149 PF13664.6 EMR68365.1 - 1.5e-19 70.2 5.6 2.8e-18 66.1 3.4 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4149) DUF5510 PF17629.2 EMR68365.1 - 0.039 13.9 0.0 0.098 12.6 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5510) Ribosomal_L24e PF01246.20 EMR68367.1 - 1.9e-32 111.3 5.6 4.1e-32 110.2 5.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Ku_PK_bind PF08785.11 EMR68368.1 - 3e-34 117.7 0.1 7.5e-34 116.5 0.0 1.7 2 0 0 2 2 2 1 Ku C terminal domain like Ku PF02735.16 EMR68368.1 - 4.2e-29 101.7 0.0 7.8e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EMR68368.1 - 1.5e-12 47.7 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EMR68368.1 - 0.048 14.4 0.1 0.66 10.7 0.0 2.4 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Daxx PF03344.15 EMR68368.1 - 0.15 12.1 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain ING PF12998.7 EMR68370.1 - 0.001 19.6 0.0 0.0029 18.1 0.0 1.8 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding IMUP PF15761.5 EMR68370.1 - 8.2 7.2 16.4 5.5 7.7 1.5 4.2 4 0 0 4 4 4 0 Immortalisation up-regulated protein Topoisom_bac PF01131.20 EMR68371.1 - 5.8e-86 289.1 0.1 1.7e-80 271.0 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 EMR68371.1 - 3.9e-17 62.3 0.0 8.5e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain RdRP_1 PF00680.20 EMR68371.1 - 0.044 12.3 0.0 0.07 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF908 PF06012.12 EMR68372.1 - 0.007 15.8 2.1 0.011 15.2 2.1 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) CBP_CCPA PF17040.5 EMR68372.1 - 0.021 15.4 1.8 1.6 9.3 3.6 2.2 2 0 0 2 2 2 0 Cellulose-complementing protein A SpoIIIAH PF12685.7 EMR68372.1 - 0.047 13.5 2.5 0.16 11.8 2.5 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein Dicty_REP PF05086.12 EMR68372.1 - 0.46 8.4 4.8 0.61 8.0 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DnaJ PF00226.31 EMR68373.1 - 4e-06 26.9 0.0 6.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 EMR68373.1 - 2e-05 24.6 0.0 2.2e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.6 EMR68373.1 - 0.026 14.2 2.2 0.042 13.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Ion_trans_N PF08412.10 EMR68373.1 - 0.12 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Ion transport protein N-terminal Rad60-SLD PF11976.8 EMR68375.1 - 1.5e-06 27.9 0.0 3.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EMR68375.1 - 4.2e-05 23.2 0.0 8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family PB1 PF00564.24 EMR68375.1 - 0.044 13.7 0.0 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 PB1 domain RtcR PF06956.11 EMR68375.1 - 0.049 13.0 0.1 0.091 12.2 0.1 1.4 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase DUF3602 PF12223.8 EMR68377.1 - 3.4e-08 34.0 23.9 0.0086 16.7 0.2 4.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3602) Stb3 PF10330.9 EMR68378.1 - 9.9e-38 128.1 0.0 1.7e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein NnrS PF05940.12 EMR68378.1 - 0.22 10.9 0.7 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 NnrS protein SQHop_cyclase_C PF13243.6 EMR68379.1 - 5.9e-44 150.5 2.3 3.6e-42 144.6 0.9 2.7 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EMR68379.1 - 5.7e-38 130.7 4.9 3.4e-33 115.0 0.5 3.8 3 2 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EMR68379.1 - 6.7e-30 102.5 3.5 1.5e-09 37.4 0.1 4.8 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EMR68379.1 - 1.4e-07 30.9 0.1 4.9e-07 29.1 0.1 1.7 1 1 1 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 EMR68379.1 - 0.012 15.0 0.1 2.7 7.3 0.0 3.3 3 1 1 4 4 4 0 Pectic acid lyase Abhydrolase_1 PF00561.20 EMR68380.1 - 5.8e-14 52.4 0.0 3.8e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR68380.1 - 2.7e-09 38.0 0.8 3.3e-09 37.7 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR68380.1 - 8.9e-05 21.9 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMR68380.1 - 0.00062 18.6 0.0 0.00079 18.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 EMR68380.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Tannase PF07519.11 EMR68380.1 - 0.18 10.6 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Glyco_hydro_61 PF03443.14 EMR68381.1 - 0.01 15.8 0.3 0.039 13.9 0.0 2.1 2 1 0 2 2 2 0 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 EMR68381.1 - 0.017 15.8 0.1 0.11 13.2 0.1 2.3 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading SOG2 PF10428.9 EMR68381.1 - 9.3 5.3 21.0 14 4.8 21.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PHO4 PF01384.20 EMR68382.1 - 2.3e-101 339.2 18.5 2.7e-101 339.0 18.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family Col_cuticle_N PF01484.17 EMR68382.1 - 0.26 11.4 0.2 0.26 11.4 0.2 3.0 4 0 0 4 4 4 0 Nematode cuticle collagen N-terminal domain UPF0444 PF15475.6 EMR68382.1 - 0.59 10.4 7.4 1.2 9.4 0.3 2.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 SGS PF05002.15 EMR68383.1 - 5.2e-32 109.8 3.3 1.9e-31 108.0 3.3 2.1 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EMR68383.1 - 6.3e-11 43.1 0.3 1.2e-10 42.3 0.3 1.5 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EMR68383.1 - 8.1e-09 34.9 0.8 0.012 15.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMR68383.1 - 4.8e-05 23.0 0.6 2.1 8.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMR68383.1 - 0.00025 21.6 1.6 0.0013 19.3 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF2057 PF09829.9 EMR68383.1 - 0.01 16.1 0.3 0.01 16.1 0.3 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) TPR_19 PF14559.6 EMR68383.1 - 0.023 15.2 0.4 3.5 8.2 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMR68383.1 - 0.26 11.6 1.6 0.63 10.4 0.5 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR68383.1 - 0.74 10.8 4.3 23 6.2 0.6 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4267 PF14087.6 EMR68384.1 - 1.1e-19 70.6 2.4 1.3e-19 70.3 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Beta_helix PF13229.6 EMR68385.1 - 1.4e-06 28.3 19.0 0.0032 17.3 13.7 2.3 1 1 1 2 2 2 2 Right handed beta helix region Sugar_tr PF00083.24 EMR68386.1 - 2.5e-98 329.9 21.0 2.9e-98 329.7 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR68386.1 - 2.7e-18 66.0 56.2 1.8e-17 63.3 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR68386.1 - 0.00056 18.5 0.3 0.001 17.6 0.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trp_oprn_chp PF09534.10 EMR68386.1 - 0.0019 18.0 2.1 0.33 10.7 0.2 3.0 2 1 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 EMR68386.1 - 0.095 12.5 2.2 3.6 7.5 0.1 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 EMR68387.1 - 4.4e-18 65.3 51.4 8.6e-11 41.3 28.7 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR68387.1 - 1.9e-13 49.8 24.8 4e-13 48.7 24.8 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 EMR68388.1 - 2.1e-57 194.9 0.0 2.9e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EMR68389.1 - 0.11 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans PF04082.18 EMR68390.1 - 6.2e-05 22.1 0.0 9.7e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BBE PF08031.12 EMR68392.1 - 2.6e-09 37.0 0.0 5.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 EMR68393.1 - 5.6e-21 74.9 2.6 6.6e-21 74.7 2.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68393.1 - 6.7e-18 65.1 2.3 8.7e-18 64.7 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68393.1 - 2.9e-08 33.8 0.4 3.5e-08 33.6 0.4 1.0 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 EMR68393.1 - 0.0042 17.3 0.3 0.0053 16.9 0.3 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ldh_1_N PF00056.23 EMR68393.1 - 0.039 14.0 0.6 0.074 13.1 0.4 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EMR68393.1 - 0.041 13.0 0.4 0.046 12.9 0.4 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein BRE1 PF08647.11 EMR68394.1 - 0.032 14.3 0.9 0.032 14.3 0.9 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 EMR68394.1 - 0.039 14.1 1.4 0.15 12.3 0.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MctB PF11382.8 EMR68394.1 - 0.062 13.0 2.1 0.057 13.1 1.0 1.6 1 1 0 1 1 1 0 Copper transport outer membrane protein, MctB Phage_GP20 PF06810.11 EMR68394.1 - 0.073 12.9 0.5 0.073 12.9 0.5 2.1 1 1 0 2 2 2 0 Phage minor structural protein GP20 DUF16 PF01519.16 EMR68394.1 - 0.18 12.3 4.2 0.35 11.4 1.9 2.0 1 1 0 2 2 2 0 Protein of unknown function DUF16 Atg14 PF10186.9 EMR68394.1 - 0.32 10.0 9.8 0.26 10.3 7.5 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med3 PF11593.8 EMR68394.1 - 0.35 10.0 3.6 0.48 9.6 3.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2203 PF09969.9 EMR68394.1 - 0.37 11.5 5.2 0.26 12.0 1.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) PI3K_P85_iSH2 PF16454.5 EMR68394.1 - 0.6 9.7 8.3 0.064 12.9 1.9 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ATG16 PF08614.11 EMR68394.1 - 0.84 9.8 15.0 1.2 9.3 6.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4140 PF13600.6 EMR68394.1 - 1 9.8 8.2 0.39 11.2 2.4 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ABC_tran_CTD PF16326.5 EMR68394.1 - 1.1 9.6 11.7 0.093 13.0 3.7 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain Miff PF05644.11 EMR68394.1 - 1.2 8.7 7.7 0.072 12.7 1.9 1.8 1 1 1 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff DUF641 PF04859.12 EMR68394.1 - 4.8 7.5 9.5 5.4 7.4 1.8 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF724 PF05266.14 EMR68394.1 - 4.9 6.9 9.6 0.83 9.5 2.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 EMR68394.1 - 5.3 4.8 6.3 7.9 4.3 5.5 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 EMR68394.1 - 7.3 6.7 10.6 3.2 7.8 3.7 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EMR68394.1 - 7.7 7.0 10.4 3.1 8.3 2.6 2.6 2 1 0 2 2 2 0 Cell division protein ZapB IBR PF01485.21 EMR68395.1 - 1.3e-09 38.1 34.2 9.3e-08 32.2 8.7 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 EMR68395.1 - 0.0073 16.2 6.2 0.0073 16.2 6.2 4.1 3 2 0 3 3 3 1 zinc-RING finger domain MFS_1 PF07690.16 EMR68396.1 - 1.2e-17 63.9 47.6 4.7e-16 58.7 21.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR68396.1 - 1.3e-06 27.6 11.9 1.3e-06 27.6 11.9 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter Mntp PF02659.15 EMR68396.1 - 0.0076 16.0 1.4 0.0076 16.0 1.4 3.8 4 2 0 4 4 4 1 Putative manganese efflux pump DUF1726 PF08351.11 EMR68396.1 - 0.052 13.5 0.4 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) ADH_zinc_N PF00107.26 EMR68397.1 - 2.6e-15 56.5 1.1 5.4e-15 55.5 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR68397.1 - 1.2e-08 36.0 0.0 1.3e-07 32.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR68397.1 - 0.00016 21.5 0.1 0.00039 20.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EMR68397.1 - 0.008 15.5 0.5 0.015 14.6 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 EMR68397.1 - 0.026 13.9 0.7 0.068 12.6 0.7 1.6 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF1593 PF07632.11 EMR68398.1 - 7.3e-80 268.1 0.0 1.3e-79 267.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) IU_nuc_hydro PF01156.19 EMR68398.1 - 0.15 11.6 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase adh_short PF00106.25 EMR68399.1 - 1.5e-15 57.2 0.0 2.3e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMR68399.1 - 8e-05 22.6 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMR68399.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SET PF00856.28 EMR68400.1 - 4.4e-10 40.2 0.0 1.3e-09 38.7 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EMR68400.1 - 4.5e-08 33.0 11.0 9.4e-08 32.0 11.0 1.6 1 0 0 1 1 1 1 MYND finger FolB PF02152.18 EMR68401.1 - 1e-08 35.7 0.0 1.8e-05 25.2 0.1 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase Acetyltransf_1 PF00583.25 EMR68401.1 - 1.9e-07 31.3 0.0 4.5e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR68401.1 - 4.3e-05 23.9 0.0 8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR68401.1 - 8.8e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR68401.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein TFIIA PF03153.13 EMR68402.1 - 0.15 12.0 5.5 0.16 11.9 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_1 PF00515.28 EMR68403.1 - 1.1e-23 82.0 1.7 1.1e-07 31.3 0.0 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EMR68403.1 - 2.2e-21 74.2 7.3 3.7e-06 26.6 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EMR68403.1 - 2.9e-16 58.9 4.4 1.5e-07 30.9 0.0 4.8 3 2 2 5 5 5 3 TPR repeat TPR_16 PF13432.6 EMR68403.1 - 2.3e-15 57.0 10.6 5.2e-06 27.0 0.4 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EMR68403.1 - 1.7e-14 52.8 0.6 2.9e-05 23.9 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMR68403.1 - 7.1e-14 51.1 1.7 0.065 13.6 0.1 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EMR68403.1 - 7.1e-13 48.2 13.9 8.9e-05 23.0 0.1 6.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMR68403.1 - 1.6e-12 47.8 6.6 0.0011 19.4 0.1 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMR68403.1 - 5.7e-12 44.8 4.3 0.0075 16.2 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMR68403.1 - 1.1e-09 38.3 6.1 0.00011 22.3 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMR68403.1 - 1.7e-08 34.7 10.6 1.1e-05 25.6 0.5 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EMR68403.1 - 1.2e-07 31.9 3.7 0.055 13.8 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EMR68403.1 - 1.9e-06 28.1 7.1 0.67 10.7 0.1 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR68403.1 - 6.7e-05 23.0 2.9 0.1 12.8 0.3 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EMR68403.1 - 0.00033 20.6 0.0 0.23 11.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1641 PF07849.11 EMR68403.1 - 0.1 12.5 0.2 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_10 PF13374.6 EMR68403.1 - 0.1 12.5 10.0 0.19 11.7 0.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Gly-rich_Ago1 PF12764.7 EMR68403.1 - 2.2 9.1 8.9 0.18 12.6 1.5 2.4 1 1 1 2 2 2 0 Glycine-rich region of argonaut RNase_T PF00929.24 EMR68404.1 - 9.2e-12 45.8 0.0 2.9e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Exonuclease p450 PF00067.22 EMR68405.1 - 3.1e-54 184.4 0.0 3.9e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EMR68406.1 - 1e-28 100.3 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAST_2 PF08368.12 EMR68407.1 - 0.0024 18.6 0.1 0.72 10.7 0.0 2.4 2 0 0 2 2 2 2 FAST kinase-like protein, subdomain 2 Glyco_hydro_76 PF03663.14 EMR68408.1 - 1.5e-111 373.4 17.8 1.8e-111 373.2 17.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RINGv PF12906.7 EMR68409.1 - 0.00018 21.5 3.8 0.0003 20.9 3.8 1.3 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EMR68409.1 - 0.00038 20.6 1.0 0.00068 19.8 1.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EMR68409.1 - 0.011 16.0 4.1 0.018 15.3 4.1 1.3 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 EMR68409.1 - 0.13 12.2 2.8 0.21 11.5 2.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 EMR68409.1 - 0.21 11.4 1.6 0.4 10.6 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EMR68409.1 - 1.3 8.9 4.3 2.5 8.0 4.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lactonase PF10282.9 EMR68410.1 - 4.4e-22 78.8 0.0 1.1e-21 77.6 0.0 1.6 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller NmrA PF05368.13 EMR68411.1 - 5.1e-19 68.8 0.0 6.7e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR68411.1 - 1.1e-13 51.5 0.0 2.9e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EMR68411.1 - 4.7e-09 36.1 0.2 1.5e-08 34.4 0.2 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMR68411.1 - 5.1e-06 26.8 0.8 8.9e-06 26.0 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EMR68411.1 - 1.6e-05 24.9 0.1 2.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EMR68411.1 - 5.5e-05 22.3 0.1 8.1e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMR68411.1 - 0.00021 20.8 0.1 0.011 15.1 0.1 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EMR68411.1 - 0.0005 20.3 1.2 0.0012 19.1 0.4 1.9 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_4 PF07993.12 EMR68411.1 - 0.00082 18.6 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EMR68411.1 - 0.0017 17.6 0.4 0.0041 16.3 0.2 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 EMR68411.1 - 0.0018 18.4 0.5 0.0044 17.1 0.5 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 EMR68411.1 - 0.0025 18.4 0.9 0.0049 17.4 0.3 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMR68411.1 - 0.0036 17.3 0.9 0.011 15.8 0.4 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 EMR68411.1 - 0.0051 16.3 1.0 0.0068 15.9 0.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 EMR68411.1 - 0.0068 16.8 0.1 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.16 EMR68411.1 - 0.017 14.8 0.1 0.043 13.5 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 EMR68411.1 - 0.024 13.7 0.3 0.056 12.5 0.3 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain LpxI_N PF17930.1 EMR68411.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 LpxI N-terminal domain DUF456 PF04306.13 EMR68413.1 - 1.1e-05 25.8 9.3 1.3e-05 25.5 9.3 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 EMR68413.1 - 0.0012 18.8 21.7 0.0012 18.8 21.7 2.3 2 1 0 2 2 2 1 Glycine zipper DUF575 PF04746.12 EMR68413.1 - 0.082 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF575) Gly-zipper_YMGG PF13441.6 EMR68413.1 - 0.96 9.2 27.3 3.6 7.4 27.3 2.1 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 EMR68413.1 - 1.1 9.1 30.1 0.19 11.6 21.9 2.7 2 1 0 2 2 2 0 Glycine zipper 2TM domain Patatin PF01734.22 EMR68414.1 - 7.4e-24 85.1 0.0 1.2e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Cupin_1 PF00190.22 EMR68415.1 - 3e-42 143.8 0.0 2.2e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EMR68415.1 - 1.4e-27 95.2 1.6 1.5e-13 50.2 0.5 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EMR68415.1 - 3.2e-08 33.1 0.1 0.00032 20.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EMR68415.1 - 1.8e-07 31.2 0.2 0.00043 20.2 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EMR68415.1 - 0.0044 16.9 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 EMR68415.1 - 0.037 14.2 0.7 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 ARD/ARD' family Cupin_7 PF12973.7 EMR68415.1 - 0.044 13.7 0.2 0.43 10.5 0.1 2.5 2 1 0 2 2 2 0 ChrR Cupin-like domain 3-HAO PF06052.12 EMR68415.1 - 0.095 12.3 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Sulfate_transp PF00916.20 EMR68416.1 - 1.2e-76 258.0 13.1 2.3e-76 257.1 13.1 1.5 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMR68416.1 - 3.1e-07 30.0 0.0 5.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain B12D PF06522.11 EMR68416.1 - 0.061 13.1 0.5 0.37 10.6 0.0 2.5 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF5493 PF17597.2 EMR68416.1 - 0.2 11.9 3.0 4.2 7.7 0.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5493) NAD_binding_4 PF07993.12 EMR68418.1 - 2e-32 112.4 0.0 3.6e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EMR68418.1 - 1.6e-19 69.8 0.0 2.6e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EMR68418.1 - 3.2e-11 43.2 0.0 5.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR68418.1 - 6e-10 39.3 0.0 3.3e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 EMR68418.1 - 0.12 12.2 0.0 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 KR domain DUF1275 PF06912.11 EMR68419.1 - 7.1e-48 163.1 15.9 8.5e-48 162.8 15.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Fungal_trans PF04082.18 EMR68420.1 - 0.0022 17.1 0.0 0.0031 16.6 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Oxysterol_BP PF01237.18 EMR68421.1 - 5.5e-59 199.9 0.7 1.5e-56 191.9 0.7 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF4990 PF16380.5 EMR68422.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function MFS_1 PF07690.16 EMR68424.1 - 3.7e-16 59.0 44.6 2.8e-14 52.8 40.1 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Imm17 PF15562.6 EMR68424.1 - 0.0032 17.3 8.6 0.69 9.8 2.3 3.1 2 0 0 2 2 2 2 Immunity protein 17 Saf_2TM PF18303.1 EMR68424.1 - 0.028 14.0 0.4 0.066 12.8 0.4 1.6 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF373 PF04123.13 EMR68424.1 - 0.46 9.9 6.7 0.73 9.2 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4307 PF14155.6 EMR68424.1 - 9.7 6.1 6.3 0.5 10.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Carn_acyltransf PF00755.20 EMR68425.1 - 7.6e-90 302.2 0.0 1.1e-89 301.7 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 EMR68425.1 - 1.5e-65 221.3 0.0 2.9e-65 220.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EMR68425.1 - 7.7e-56 189.5 0.2 2.3e-55 187.9 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EMR68425.1 - 3.8e-55 187.6 0.3 9.2e-55 186.4 0.3 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR68425.1 - 6.5e-34 116.5 0.1 1.8e-33 115.0 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EMR68425.1 - 7.9e-30 104.1 1.7 9.6e-21 74.5 0.2 2.9 1 1 1 2 2 2 2 KR domain KAsynt_C_assoc PF16197.5 EMR68425.1 - 7.6e-19 68.2 0.0 2.3e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EMR68425.1 - 1.6e-07 31.6 0.2 5.4e-07 29.9 0.2 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 EMR68425.1 - 0.00017 21.5 0.2 0.00076 19.5 0.2 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EMR68425.1 - 0.013 16.2 0.0 0.1 13.3 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_33 PF10017.9 EMR68425.1 - 0.076 12.2 0.0 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Potass_KdpF PF09604.10 EMR68425.1 - 0.23 11.5 0.9 0.71 9.9 0.9 1.9 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) WSC PF01822.19 EMR68426.1 - 8.3e-18 64.4 3.2 8.3e-18 64.4 3.2 1.9 2 0 0 2 2 2 1 WSC domain SSP160 PF06933.11 EMR68426.1 - 0.19 9.9 18.8 0.24 9.5 18.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glycoprotein PF03409.15 EMR68426.1 - 0.58 8.9 13.2 0.73 8.6 13.2 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein Dicty_REP PF05086.12 EMR68426.1 - 1.9 6.4 5.3 2.4 6.1 5.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EMR68426.1 - 8.3 6.4 36.0 11 6.0 36.0 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M28 PF04389.17 EMR68428.1 - 5.6e-34 117.6 0.0 8.5e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMR68428.1 - 5.5e-08 32.7 0.8 1.4e-07 31.4 0.8 1.8 1 0 0 1 1 1 1 PA domain Cpn60_TCP1 PF00118.24 EMR68429.1 - 7.9e-88 295.2 11.3 1.5e-87 294.3 11.3 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 EMR68429.1 - 0.08 13.3 0.2 0.22 11.9 0.2 1.8 1 0 0 1 1 1 0 Transcriptional regulator adh_short PF00106.25 EMR68430.1 - 1.5e-14 53.9 0.0 1.3e-12 47.6 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68430.1 - 9.3e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR68430.1 - 0.0055 16.2 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR68430.1 - 0.081 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 KR domain Inositol_P PF00459.25 EMR68432.1 - 1.2e-34 120.1 0.1 4.1e-34 118.3 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Glucosamine_iso PF01182.20 EMR68434.1 - 8.1e-69 231.9 0.0 9.3e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Efg1 PF10153.9 EMR68435.1 - 1.8e-33 115.3 8.6 4.4e-33 114.1 8.6 1.7 1 0 0 1 1 1 1 rRNA-processing protein Efg1 MCR_D PF02505.14 EMR68435.1 - 0.018 14.9 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D ketoacyl-synt PF00109.26 EMR68436.1 - 6.9e-59 199.5 0.4 1.7e-57 194.9 0.2 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ubiq_cyt_C_chap PF03981.12 EMR68436.1 - 4.5e-37 127.3 1.2 1.3e-36 125.8 1.2 1.8 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Ketoacyl-synt_C PF02801.22 EMR68436.1 - 2.3e-21 76.0 0.1 2.2e-19 69.6 0.1 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EMR68436.1 - 3.2e-07 30.0 0.2 7.8e-05 22.2 0.1 3.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain AAA_12 PF13087.6 EMR68437.1 - 5e-27 94.8 0.0 8e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EMR68437.1 - 3.6e-06 26.7 0.0 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 EMR68437.1 - 0.00033 20.5 0.0 0.00033 20.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMR68437.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMR68437.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vfa1 PF08432.10 EMR68437.1 - 0.19 12.0 8.0 0.31 11.3 8.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 EMR68437.1 - 1.4 8.6 3.0 2.5 7.7 3.0 1.4 1 0 0 1 1 1 0 FAM176 family TPR_2 PF07719.17 EMR68438.1 - 1.1e-25 87.6 12.7 0.0076 16.3 0.0 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 EMR68438.1 - 2.6e-24 84.0 17.0 4.1e-05 23.2 0.1 11.7 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 EMR68438.1 - 6.3e-23 79.0 11.9 0.00087 19.3 0.1 11.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMR68438.1 - 1e-15 57.0 28.1 0.015 16.1 0.1 12.7 11 2 4 15 15 14 4 Tetratricopeptide repeat TPR_7 PF13176.6 EMR68438.1 - 4.3e-15 54.6 16.0 0.0016 18.3 0.0 9.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMR68438.1 - 9e-15 54.7 10.7 0.0026 18.0 0.0 9.2 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 EMR68438.1 - 2.2e-14 53.0 15.5 0.00077 19.9 0.0 10.0 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMR68438.1 - 5e-11 42.2 11.8 0.43 11.1 0.1 11.5 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMR68438.1 - 5.3e-11 42.0 5.3 0.45 10.2 0.1 7.8 7 0 0 7 7 7 3 TPR repeat TPR_19 PF14559.6 EMR68438.1 - 1.7e-10 41.3 33.2 0.00021 21.7 0.4 10.8 10 4 2 12 12 11 3 Tetratricopeptide repeat TPR_10 PF13374.6 EMR68438.1 - 1.5e-09 37.4 10.1 0.16 11.9 0.0 8.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMR68438.1 - 9.5e-08 32.6 15.2 0.066 13.9 0.1 7.6 7 1 1 8 8 6 2 Tetratricopeptide repeat DUF4810 PF16068.5 EMR68438.1 - 0.00072 20.0 4.2 4.4 7.9 0.1 5.6 4 1 1 5 5 5 1 Domain of unknown function (DUF4810) ANAPC3 PF12895.7 EMR68438.1 - 0.041 14.1 7.9 6.6 7.0 0.2 5.3 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EMR68438.1 - 0.39 10.8 4.2 6.9 6.8 0.0 4.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Iwr1 PF08574.10 EMR68440.1 - 2.6e-16 60.4 12.3 2.6e-16 60.4 12.3 2.5 3 0 0 3 3 3 1 Transcription factor Iwr1 FAD_binding_4 PF01565.23 EMR68442.1 - 3.5e-15 56.0 0.0 5.9e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR68442.1 - 0.00032 20.7 0.1 0.00071 19.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 EMR68442.1 - 0.048 13.5 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.10 EMR68442.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD-oxidase_C PF02913.19 EMR68442.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Hydrolase_6 PF13344.6 EMR68445.1 - 4.3e-29 100.6 0.0 6.9e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR68445.1 - 5.6e-16 58.4 0.0 3.7e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EMR68445.1 - 4.1e-09 37.0 0.1 0.0095 16.2 0.0 3.0 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR68445.1 - 1.9e-05 24.8 0.2 0.19 11.8 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase HET PF06985.11 EMR68446.1 - 8.1e-21 74.9 0.0 3.3e-20 72.9 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zinc_ribbon_16 PF17034.5 EMR68447.1 - 7.9e-17 61.6 11.2 2.3e-16 60.1 11.1 1.9 1 1 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EMR68447.1 - 1.4e-07 31.0 4.8 1.4e-07 31.0 4.8 2.4 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type TPR_14 PF13428.6 EMR68447.1 - 0.085 13.7 0.0 2.9 8.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DZR PF12773.7 EMR68447.1 - 1.9 8.6 9.4 1.1e+02 3.0 9.6 3.0 1 1 1 2 2 2 0 Double zinc ribbon Brix PF04427.18 EMR68448.1 - 1.2e-23 84.2 0.0 1.8e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain YdfA_immunity PF12127.8 EMR68448.1 - 0.1 11.7 2.9 0.16 11.0 2.9 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial BUD22 PF09073.10 EMR68448.1 - 1.1 8.5 20.9 1.5 8.1 20.9 1.1 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.16 EMR68449.1 - 2.1e-38 132.2 43.6 4.1e-37 127.9 40.2 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EMR68450.1 - 1.2e-69 234.6 1.9 2.5e-68 230.3 1.9 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR68450.1 - 6.8e-54 182.9 0.1 1.1e-53 182.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EMR68450.1 - 4.3e-24 84.6 0.0 1e-23 83.5 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EMR68450.1 - 1.5e-06 27.8 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMR68450.1 - 2.6e-06 26.5 0.0 5.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 EMR68450.1 - 2.7e-06 27.8 0.0 8.6e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EMR68450.1 - 0.0017 18.8 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.23 EMR68450.1 - 0.011 15.7 0.2 0.046 13.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EMR68450.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EMR68450.1 - 0.025 13.6 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EMR68450.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DND1_DSRM PF14709.7 EMR68451.1 - 0.025 14.8 0.1 0.53 10.6 0.0 2.4 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Acetyltransf_1 PF00583.25 EMR68452.1 - 3.3e-08 33.8 0.0 6.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR68452.1 - 7.6e-08 32.7 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR68452.1 - 1.6e-06 28.2 1.5 1.9e-06 28.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR68452.1 - 2.3e-06 27.6 0.0 4.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EMR68452.1 - 0.0015 18.7 0.1 0.0038 17.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR68452.1 - 0.0091 15.9 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EMR68452.1 - 0.024 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3632 PF12311.8 EMR68453.1 - 1e-34 120.5 2.2 1.9e-34 119.6 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) OPT PF03169.15 EMR68455.1 - 1.1e-139 467.0 42.6 4.1e-112 375.9 35.6 2.3 1 1 1 2 2 2 2 OPT oligopeptide transporter protein CcmD PF04995.14 EMR68455.1 - 0.076 13.1 0.7 0.31 11.2 0.7 2.1 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) F-box PF00646.33 EMR68456.1 - 0.0026 17.6 0.1 0.0046 16.8 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMR68456.1 - 0.024 14.5 0.2 0.05 13.5 0.2 1.5 1 0 0 1 1 1 0 F-box-like RNA_pol_I_A49 PF06870.12 EMR68457.1 - 5e-100 335.1 0.0 6.1e-100 334.8 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF3535 PF12054.8 EMR68457.1 - 0.047 12.9 0.7 0.085 12.1 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3535) DHFR_1 PF00186.19 EMR68458.1 - 1.1e-28 100.0 0.0 2.3e-28 98.9 0.0 1.6 1 1 0 1 1 1 1 Dihydrofolate reductase PhyH PF05721.13 EMR68458.1 - 0.0011 19.3 0.0 0.0043 17.3 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) bZIP_1 PF00170.21 EMR68459.1 - 1.5e-05 25.0 3.0 3e-05 24.0 3.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor Cadherin_tail PF15974.5 EMR68459.1 - 0.45 10.8 4.1 0.26 11.6 1.3 2.0 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Complex1_LYR PF05347.15 EMR68461.1 - 1e-06 28.6 0.0 5.3e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Complex 1 protein (LYR family) UQ_con PF00179.26 EMR68461.1 - 2.7e-05 23.8 0.1 5.3e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NAM-associated PF14303.6 EMR68461.1 - 0.03 15.1 2.0 0.03 15.1 2.0 2.4 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain AAA PF00004.29 EMR68462.1 - 2e-14 54.2 0.0 3.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR68462.1 - 3.8e-05 24.1 0.0 0.00012 22.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR68462.1 - 0.00043 20.6 4.6 0.047 14.0 0.1 3.6 3 1 1 4 4 4 2 AAA domain RuvB_N PF05496.12 EMR68462.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EMR68462.1 - 0.041 14.0 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMR68462.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EMR68462.1 - 0.12 12.1 0.3 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein 4HBT PF03061.22 EMR68465.1 - 1e-12 48.2 0.9 1.8e-12 47.5 0.9 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EMR68465.1 - 0.047 13.8 0.1 0.06 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Aldedh PF00171.22 EMR68466.1 - 1.9e-181 603.6 0.0 2.2e-181 603.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMR68466.1 - 0.0087 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EMR68466.1 - 0.035 13.5 0.0 5.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Band_7 PF01145.25 EMR68467.1 - 1.4e-27 96.8 0.4 1.4e-27 96.8 0.4 1.8 3 0 0 3 3 3 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EMR68467.1 - 6.5e-22 77.4 0.3 1.9e-21 75.9 0.3 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 EMR68467.1 - 0.019 14.3 0.2 0.031 13.6 0.2 1.4 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 EMR68467.1 - 0.047 13.4 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Aa_trans PF01490.18 EMR68468.1 - 3.2e-32 111.7 35.0 3.9e-32 111.5 35.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HRI1 PF16815.5 EMR68468.1 - 6.4e-24 84.9 0.0 9.5e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Protein HRI1 Amidase PF01425.21 EMR68469.1 - 3.5e-34 118.6 0.4 9.4e-34 117.1 0.5 1.6 2 0 0 2 2 2 1 Amidase HCV_NS1 PF01560.17 EMR68469.1 - 0.19 10.3 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 UQ_con PF00179.26 EMR68470.1 - 5.7e-40 136.2 0.0 6.3e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMR68470.1 - 3.6e-05 23.5 0.0 4.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMR68470.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EMR68470.1 - 0.045 13.6 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 UEV domain TraB PF01963.17 EMR68470.1 - 0.24 11.3 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 TraB family MAP65_ASE1 PF03999.12 EMR68472.1 - 6.6e-74 249.7 24.1 7.3e-74 249.5 20.0 2.1 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) DUF948 PF06103.11 EMR68472.1 - 0.2 12.0 1.0 4.1 7.7 0.7 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 EMR68472.1 - 1 9.7 7.4 7.3 7.0 3.0 3.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3510 PF12022.8 EMR68472.1 - 1.2 9.5 4.2 0.39 11.1 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Occludin_ELL PF07303.13 EMR68472.1 - 1.6 9.5 5.3 2.7 8.8 0.3 3.7 2 2 0 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.12 EMR68472.1 - 1.6 8.8 3.9 3.8 7.6 1.3 2.8 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 EMR68472.1 - 5.7 7.5 16.8 0.5 10.9 1.1 4.2 3 1 1 4 4 4 0 Spectrin repeat SKA2 PF16740.5 EMR68472.1 - 7.6 6.4 7.8 5.9 6.7 0.2 3.8 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 Sybindin PF04099.12 EMR68473.1 - 1.4e-21 76.9 0.0 2.1e-21 76.3 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family FA_desaturase PF00487.24 EMR68474.1 - 1.2e-07 31.8 3.6 1.7e-07 31.4 3.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF5530 PF17670.1 EMR68474.1 - 0.0078 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5530) DUF4208 PF13907.6 EMR68474.1 - 0.033 14.6 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) CATSPERG PF15064.6 EMR68474.1 - 0.1 10.4 0.0 0.12 10.1 0.0 1.0 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma HTH_23 PF13384.6 EMR68474.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_hydro_cc PF11790.8 EMR68475.1 - 1.9e-26 93.1 0.0 2.2e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PH PF00169.29 EMR68476.1 - 3.2e-11 43.7 0.1 4.8e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EMR68476.1 - 0.0002 21.8 0.9 0.00042 20.7 0.9 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EMR68476.1 - 0.076 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Peroxin-3 PF04882.12 EMR68477.1 - 2.5e-163 544.5 2.2 1.1e-162 542.4 0.0 2.0 2 0 0 2 2 2 1 Peroxin-3 EF-hand_4 PF12763.7 EMR68478.1 - 4.3e-05 23.4 0.0 6.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Aquarius_N PF16399.5 EMR68479.1 - 0 1105.7 0.0 0 1105.4 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EMR68479.1 - 3.7e-26 92.0 0.0 6.3e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMR68479.1 - 5.7e-21 75.5 0.0 1.5e-20 74.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMR68479.1 - 6.4e-07 29.3 0.0 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EMR68479.1 - 1.7e-05 24.9 0.0 3.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EMR68479.1 - 3.7e-05 24.1 0.0 9.5e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR68479.1 - 0.00098 19.5 0.4 0.0064 16.9 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain DnaB_C PF03796.15 EMR68479.1 - 0.0014 18.0 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 EMR68479.1 - 0.0029 18.0 0.0 0.0073 16.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EMR68479.1 - 0.0067 16.2 0.1 0.56 9.9 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EMR68479.1 - 0.033 14.0 0.8 0.1 12.4 0.1 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EMR68479.1 - 0.035 13.3 0.9 0.067 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EMR68479.1 - 0.042 14.1 0.2 0.22 11.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EMR68479.1 - 0.053 12.6 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RecA PF00154.21 EMR68479.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein SMC_N PF02463.19 EMR68479.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain INSIG PF07281.12 EMR68480.1 - 4.4e-70 235.6 0.3 7.3e-70 234.9 0.3 1.4 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) YL1 PF05764.13 EMR68480.1 - 0.0065 16.6 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Rrn6 PF10214.9 EMR68480.1 - 0.25 9.8 1.3 0.45 9.0 1.3 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ATG101 PF07855.12 EMR68481.1 - 1.7e-57 193.7 0.0 2e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Mo-co_dimer PF03404.16 EMR68481.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain efThoc1 PF11957.8 EMR68482.1 - 1.7e-110 370.0 5.8 8.4e-66 222.6 1.7 2.2 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 EMR68482.1 - 3.9e-36 124.4 0.0 6.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 EMR68482.1 - 1.5e-06 28.3 0.0 4.1e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EMR68482.1 - 0.00031 21.3 0.0 0.0009 19.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EMR68482.1 - 0.0016 18.8 0.1 0.0058 17.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMR68482.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EMR68482.1 - 0.0024 18.4 0.1 0.022 15.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMR68482.1 - 0.0057 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMR68482.1 - 0.021 15.0 0.0 0.066 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EMR68482.1 - 0.024 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EMR68482.1 - 0.026 13.6 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EMR68482.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Adeno_IVa2 PF02456.15 EMR68482.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_7 PF12775.7 EMR68482.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EMR68482.1 - 0.075 12.3 0.1 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 EMR68482.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain CMAS PF02353.20 EMR68483.1 - 1.2e-59 201.9 0.1 1.6e-59 201.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EMR68483.1 - 1.4e-09 38.0 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR68483.1 - 1.8e-08 34.9 0.0 3.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR68483.1 - 5.1e-08 33.5 0.0 1.2e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR68483.1 - 0.053 14.3 0.1 0.46 11.3 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EMR68483.1 - 0.15 11.6 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 EMR68483.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Forkhead PF00250.18 EMR68484.1 - 1.8e-35 121.0 0.2 3.4e-35 120.2 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain F-box-like PF12937.7 EMR68485.1 - 0.27 11.1 3.4 0.12 12.3 0.3 2.0 2 0 0 2 2 2 0 F-box-like WD40 PF00400.32 EMR68486.1 - 1e-07 32.5 0.0 22 6.1 0.0 7.1 8 0 0 8 8 8 2 WD domain, G-beta repeat DUF4366 PF14283.6 EMR68486.1 - 2.2 8.3 6.0 14 5.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) NAD_binding_10 PF13460.6 EMR68487.1 - 0.04 13.8 0.0 0.09 12.7 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Cellulase PF00150.18 EMR68488.1 - 1.7e-17 63.8 5.9 4.2e-17 62.5 5.9 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HSA PF07529.13 EMR68489.1 - 2.8e-13 50.0 0.4 2.8e-13 50.0 0.4 4.8 4 1 1 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.6 EMR68489.1 - 0.001 19.3 0.7 0.024 14.9 0.7 2.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_4 PF12763.7 EMR68490.1 - 2.6e-27 94.8 0.0 1.5e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EMR68490.1 - 0.0023 18.3 2.4 0.72 10.4 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EMR68490.1 - 0.0024 17.3 0.0 3.7 7.3 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EMR68490.1 - 0.014 15.3 0.0 57 4.0 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain E3_binding PF02817.17 EMR68490.1 - 0.027 14.8 0.2 0.1 13.0 0.2 2.1 1 0 0 1 1 1 0 e3 binding domain LPP PF04728.13 EMR68490.1 - 2.9 8.4 12.3 0.096 13.1 0.3 4.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper FPP PF05911.11 EMR68490.1 - 9.1 4.3 40.8 0.3 9.2 2.0 2.4 3 0 0 3 3 3 0 Filament-like plant protein, long coiled-coil Glyco_hydro_17 PF00332.18 EMR68491.1 - 2.1e-06 27.5 0.1 3.3e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 EMP70 PF02990.16 EMR68492.1 - 6.1e-179 596.0 4.7 7.8e-179 595.7 4.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 RSN1_7TM PF02714.15 EMR68493.1 - 9.7e-76 254.7 23.1 9.7e-76 254.7 23.1 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EMR68493.1 - 1.1e-24 87.6 3.7 2.5e-15 57.1 0.9 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EMR68493.1 - 4.2e-18 65.3 0.0 1.6e-17 63.4 0.0 2.1 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DoxX_3 PF13781.6 EMR68493.1 - 3 8.5 10.8 0.59 10.8 2.0 2.9 2 1 0 2 2 2 0 DoxX-like family RibD_C PF01872.17 EMR68494.1 - 1.5e-21 77.2 0.0 2.3e-20 73.3 0.0 2.3 1 1 0 1 1 1 1 RibD C-terminal domain DJ-1_PfpI PF01965.24 EMR68495.1 - 5e-11 42.7 0.0 8.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMR68495.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like Hamartin PF04388.12 EMR68496.1 - 0.0065 15.2 1.2 0.0065 15.2 1.2 5.4 2 1 3 5 5 5 3 Hamartin protein MSL1_dimer PF16801.5 EMR68496.1 - 0.042 13.6 0.5 0.13 12.0 0.5 1.9 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Macoilin PF09726.9 EMR68496.1 - 0.055 12.0 33.0 1.3 7.5 26.9 2.3 1 1 1 2 2 2 0 Macoilin family IFP_35_N PF07334.13 EMR68496.1 - 0.19 11.8 0.1 0.19 11.8 0.1 3.1 2 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus WSD PF15613.6 EMR68496.1 - 2.1 8.8 5.8 1.8 9.1 3.1 2.4 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Ribosomal_L23 PF00276.20 EMR68497.1 - 2.7e-10 40.5 0.0 8.2e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 Fungal_trans_2 PF11951.8 EMR68498.1 - 3e-21 75.7 0.4 4e-21 75.3 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4037 PF13228.6 EMR68498.1 - 0.2 12.5 0.7 7.8 7.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4037) DHDPS PF00701.22 EMR68499.1 - 1.5e-30 105.9 0.0 2.2e-30 105.4 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Hydrolase_like PF13242.6 EMR68499.1 - 0.079 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like MT-A70 PF05063.14 EMR68500.1 - 7.9e-30 104.0 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 MT-A70 SdrD_B PF17210.3 EMR68501.1 - 0.051 13.8 0.2 0.16 12.2 0.2 1.7 1 1 1 2 2 2 0 SdrD B-like domain Retrotran_gag_2 PF14223.6 EMR68502.1 - 0.11 12.2 0.1 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Metallophos PF00149.28 EMR68503.1 - 5.6e-09 36.8 0.7 3.1e-08 34.4 0.7 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMR68503.1 - 5.8e-06 26.6 0.0 0.068 13.4 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain PP-binding PF00550.25 EMR68504.1 - 0.00069 19.9 0.1 0.0011 19.3 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site NIF PF03031.18 EMR68505.1 - 9.7e-55 184.6 0.4 1.3e-54 184.3 0.4 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SET PF00856.28 EMR68507.1 - 3.2e-08 34.1 0.0 1.2e-07 32.2 0.0 1.9 1 1 0 1 1 1 1 SET domain tify PF06200.14 EMR68507.1 - 0.081 12.3 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 tify domain TF_Zn_Ribbon PF08271.12 EMR68508.1 - 0.0048 16.4 2.6 0.22 11.1 0.1 2.9 2 0 0 2 2 2 1 TFIIB zinc-binding DUF2225 PF09986.9 EMR68508.1 - 0.12 12.1 0.3 0.39 10.4 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) A2L_zn_ribbon PF08792.10 EMR68508.1 - 0.12 12.1 2.3 0.4 10.4 0.2 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain BUD22 PF09073.10 EMR68508.1 - 0.17 11.2 9.8 0.26 10.6 9.8 1.2 1 0 0 1 1 1 0 BUD22 zf-Di19 PF05605.12 EMR68508.1 - 0.65 10.3 6.7 2.5 8.5 1.3 3.2 2 2 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RNA_pol_3_Rpc31 PF11705.8 EMR68508.1 - 0.9 9.7 29.3 1.6 8.9 5.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 FlhC PF05280.11 EMR68508.1 - 0.94 9.2 4.4 27 4.4 1.1 3.0 3 0 0 3 3 3 0 Flagellar transcriptional activator (FlhC) zf-C2H2_4 PF13894.6 EMR68508.1 - 1.4 9.9 10.2 22 6.2 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMR68508.1 - 7.2 7.3 10.4 14 6.4 0.5 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF1713 PF08213.11 EMR68510.1 - 2.5e-10 40.1 20.7 2.5e-10 40.1 20.7 1.6 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) ABC_membrane_2 PF06472.15 EMR68511.1 - 7e-82 274.9 4.5 2.5e-48 164.8 0.0 3.5 3 1 1 4 4 4 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EMR68511.1 - 3.9e-16 59.8 0.0 7.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMR68511.1 - 0.064 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system End3 PF12761.7 EMR68511.1 - 0.078 13.1 1.1 0.17 12.0 1.1 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 AAA_16 PF13191.6 EMR68511.1 - 0.086 13.2 0.1 0.25 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EMR68511.1 - 0.1 13.1 1.2 4.5 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 EMR68512.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain DUF3388 PF11868.8 EMR68512.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) zf-C2H2_4 PF13894.6 EMR68514.1 - 0.76 10.8 6.1 1.3 10.0 1.8 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMR68514.1 - 5.3 7.7 8.1 0.57 10.7 2.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cation_efflux PF01545.21 EMR68515.1 - 5.6e-50 169.8 15.2 6.3e-49 166.4 15.2 2.0 1 1 0 1 1 1 1 Cation efflux family Glyco_hydro_3_C PF01915.22 EMR68516.1 - 1.3e-65 221.2 0.0 4.3e-65 219.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR68516.1 - 1e-39 136.8 0.0 1.9e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR68516.1 - 1.5e-23 82.7 0.1 4.5e-23 81.2 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EMR68516.1 - 5e-22 78.3 0.0 7.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 PA14 domain TetR_C_7 PF14246.6 EMR68516.1 - 0.025 14.6 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain ICMT PF04140.14 EMR68517.1 - 8.7e-28 96.6 0.3 1.9e-27 95.5 0.3 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EMR68517.1 - 5.5e-12 46.0 0.9 5.5e-12 46.0 0.9 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EMR68517.1 - 0.00052 19.6 1.3 0.00052 19.6 1.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) RRM_occluded PF16842.5 EMR68518.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-RING_UBOX PF13445.6 EMR68519.1 - 1.5e-09 37.7 3.2 7.6e-06 25.9 0.2 3.0 2 2 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 EMR68519.1 - 4.1e-07 30.2 10.5 0.00018 21.7 5.2 3.0 2 1 0 2 2 2 2 Ring finger domain zf-NOSIP PF15906.5 EMR68519.1 - 7e-07 29.3 0.0 1.6e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 EMR68519.1 - 3.5e-05 23.7 4.2 3.5e-05 23.7 4.2 2.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMR68519.1 - 5.5e-05 22.9 10.0 0.00012 21.8 0.7 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMR68519.1 - 8.5e-05 22.3 5.5 0.00052 19.8 0.8 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EMR68519.1 - 0.00013 21.4 2.6 0.00013 21.4 2.6 3.7 1 1 1 2 2 1 1 Rtf2 RING-finger FYVE PF01363.21 EMR68519.1 - 0.0037 17.4 11.3 0.0085 16.2 4.1 2.7 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 EMR68519.1 - 0.007 16.2 16.1 0.072 13.0 8.9 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 EMR68519.1 - 0.027 14.4 2.0 0.029 14.3 0.5 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EMR68519.1 - 0.27 11.1 4.2 3.4 7.6 0.1 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 EMR68519.1 - 0.39 10.9 11.2 0.82 9.9 4.5 3.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 EMR68519.1 - 0.76 9.8 9.4 0.2 11.6 1.1 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 EMR68519.1 - 2.2 8.2 17.9 0.051 13.4 5.6 3.6 3 2 1 4 4 3 0 Prokaryotic RING finger family 4 PARM PF17061.5 EMR68519.1 - 3.8 7.6 14.8 7.3 6.6 14.8 1.4 1 0 0 1 1 1 0 PARM zf-RING_4 PF14570.6 EMR68519.1 - 5.7 6.8 8.2 4.9 7.0 4.1 2.8 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 EMR68519.1 - 8.1 6.7 7.4 3.1 8.1 1.4 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Mucin PF01456.17 EMR68519.1 - 8.3 6.4 19.1 1.9 8.5 10.8 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein zinc-ribbons_6 PF07191.12 EMR68519.1 - 9.3 6.3 10.5 7.2 6.7 0.5 3.1 2 1 0 2 2 2 0 zinc-ribbons Pkinase PF00069.25 EMR68520.1 - 4.4e-76 255.7 0.0 5.1e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR68520.1 - 1.2e-37 129.6 0.0 1.6e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMR68520.1 - 0.00084 18.4 0.0 0.014 14.3 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMR68520.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EMR68520.1 - 0.053 12.8 0.1 0.14 11.5 0.1 1.8 1 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 EMR68520.1 - 0.095 12.0 0.3 0.23 10.8 0.3 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.21 EMR68521.1 - 0.028 14.0 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase Use1 PF09753.9 EMR68522.1 - 3.4e-11 43.4 2.7 3.8e-10 39.9 2.7 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 eIF3_subunit PF08597.10 EMR68522.1 - 0.027 14.4 11.3 0.3 10.9 3.3 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Vps53_N PF04100.12 EMR68522.1 - 0.07 12.1 0.5 0.11 11.5 0.5 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal CDC45 PF02724.14 EMR68522.1 - 2.2 6.5 7.4 2.8 6.1 7.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S46 PF10459.9 EMR68522.1 - 4.5 5.8 8.2 3.4 6.2 2.6 2.1 2 0 0 2 2 2 0 Peptidase S46 Synaptobrevin PF00957.21 EMR68522.1 - 5.8 6.8 6.0 9.2 6.1 0.1 2.8 3 0 0 3 3 3 0 Synaptobrevin YjbE PF11106.8 EMR68522.1 - 6.9 7.0 16.1 16 5.8 16.1 1.6 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE PAP_central PF04928.17 EMR68523.1 - 5.4e-106 353.1 0.0 7.8e-106 352.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EMR68523.1 - 4.6e-58 195.6 0.3 8.5e-58 194.7 0.3 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EMR68523.1 - 7.4e-10 39.0 0.0 1.8e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DCP2 PF05026.13 EMR68524.1 - 8.3e-29 99.8 0.9 1.4e-28 99.0 0.9 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EMR68524.1 - 8.2e-16 58.2 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PGK PF00162.19 EMR68525.1 - 1.5e-149 498.1 0.3 1.7e-149 497.9 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 EMR68525.1 - 0.0064 16.5 0.7 0.055 13.5 0.0 2.9 3 1 1 4 4 4 1 PA domain HET PF06985.11 EMR68526.1 - 2.3e-28 99.4 0.1 1.9e-27 96.4 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AidB_N PF18158.1 EMR68528.1 - 3.6e-11 43.2 0.2 9.2e-11 41.9 0.2 1.7 1 1 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 EMR68528.1 - 6.2e-11 42.7 1.0 4.4e-10 40.0 1.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMR68528.1 - 1.4e-08 34.8 0.1 6e-08 32.8 0.1 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain NACHT PF05729.12 EMR68529.1 - 2.2e-05 24.4 0.0 6.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMR68529.1 - 0.00022 21.5 0.6 0.0028 17.9 0.0 3.0 2 2 0 2 2 2 1 AAA domain Pox_A_type_inc PF04508.12 EMR68529.1 - 0.0013 18.5 2.4 0.023 14.5 0.3 2.9 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat cobW PF02492.19 EMR68529.1 - 0.009 15.6 0.2 0.054 13.1 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EMR68529.1 - 0.021 14.9 2.8 1.2 9.1 0.1 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EMR68529.1 - 0.028 14.3 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 EMR68529.1 - 0.034 14.7 1.6 0.8 10.3 0.0 3.6 3 1 1 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 EMR68529.1 - 0.071 13.2 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EMR68529.1 - 0.082 13.3 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 EMR68529.1 - 0.086 12.6 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EMR68529.1 - 0.1 12.5 0.2 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EMR68529.1 - 0.11 13.0 0.1 0.11 13.0 0.1 3.1 3 1 0 3 3 3 0 ABC transporter AAA_33 PF13671.6 EMR68529.1 - 0.14 12.4 1.8 0.33 11.1 0.1 2.6 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EMR68529.1 - 0.15 12.0 2.1 4.5 7.1 0.1 2.9 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 EMR68529.1 - 0.17 12.4 0.1 0.17 12.4 0.1 3.8 4 0 0 4 4 4 0 AAA domain SesA PF17107.5 EMR68529.1 - 0.27 11.4 3.1 0.48 10.6 1.3 2.4 3 0 0 3 3 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Seryl_tRNA_N PF02403.22 EMR68529.1 - 0.43 10.8 4.6 0.65 10.3 1.0 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DnaJ PF00226.31 EMR68530.1 - 2.5e-06 27.5 0.0 5.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Vpu PF00558.19 EMR68530.1 - 0.0056 16.4 1.2 0.014 15.2 1.2 1.7 1 0 0 1 1 1 1 Vpu protein EDS1_EP PF18117.1 EMR68530.1 - 0.27 11.7 6.4 0.65 10.5 2.7 2.7 1 1 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain Glyco_hydro_28 PF00295.17 EMR68531.1 - 1.9e-126 421.5 22.8 2.2e-126 421.3 22.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TauD PF02668.16 EMR68532.1 - 1.1e-43 149.9 0.3 1.6e-43 149.5 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ATP_bind_1 PF03029.17 EMR68533.1 - 4.9e-71 239.3 0.0 7.4e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EMR68533.1 - 0.00015 21.6 0.0 0.00046 20.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EMR68533.1 - 0.00043 19.4 0.1 0.81 8.6 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EMR68533.1 - 0.00049 19.7 0.0 0.064 12.8 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EMR68533.1 - 0.00078 19.7 0.0 0.0031 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMR68533.1 - 0.0014 18.7 0.0 0.022 14.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EMR68533.1 - 0.0027 17.9 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EMR68533.1 - 0.0031 16.8 0.0 0.0078 15.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain G-alpha PF00503.20 EMR68533.1 - 0.0035 16.6 0.0 0.068 12.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 EMR68533.1 - 0.0038 17.4 0.5 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 EMR68533.1 - 0.0039 17.0 0.0 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EMR68533.1 - 0.0046 17.4 0.0 0.012 16.0 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain FeoB_N PF02421.18 EMR68533.1 - 0.0047 16.5 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_30 PF13604.6 EMR68533.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EMR68533.1 - 0.0077 16.2 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Arf PF00025.21 EMR68533.1 - 0.013 15.0 0.0 1.1 8.7 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EMR68533.1 - 0.023 14.6 0.0 6.7 6.6 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase Thymidylate_kin PF02223.17 EMR68533.1 - 0.024 14.3 0.5 0.5 10.0 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase SRP54 PF00448.22 EMR68533.1 - 0.031 13.9 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 EMR68533.1 - 0.033 13.8 0.0 0.7 9.4 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EMR68533.1 - 0.039 14.5 0.0 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMR68533.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EMR68533.1 - 0.32 11.5 0.0 0.32 11.5 0.0 2.4 3 0 0 3 3 2 0 AAA domain DSS1_SEM1 PF05160.13 EMR68534.1 - 1.1e-25 89.5 10.6 1.5e-25 89.0 10.6 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family PBP1_TM PF14812.6 EMR68534.1 - 2.1 8.8 7.8 0.74 10.2 0.3 2.0 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mpv17_PMP22 PF04117.12 EMR68535.1 - 4.8e-21 74.7 1.3 5.6e-21 74.5 0.1 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Aldo_ket_red PF00248.21 EMR68537.1 - 9.3e-47 159.6 0.0 5.7e-45 153.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3808 PF10300.9 EMR68538.1 - 8e-126 420.6 0.0 9.9e-126 420.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 EMR68538.1 - 0.009 16.3 0.1 0.072 13.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EMR68538.1 - 0.021 14.7 0.0 0.13 12.2 0.0 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR68538.1 - 0.073 13.9 1.3 3.6 8.7 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMR68538.1 - 5.5 7.4 6.4 10 6.5 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat HAP2-GCS1 PF10699.9 EMR68539.1 - 0.095 12.7 0.7 0.23 11.4 0.7 1.6 1 0 0 1 1 1 0 Male gamete fusion factor DNA_RNApol_7kD PF03604.13 EMR68540.1 - 1.4e-15 56.7 8.5 1.8e-15 56.3 8.5 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 EMR68540.1 - 0.0025 17.8 0.4 0.0026 17.8 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EMR68540.1 - 0.0064 16.6 2.4 0.013 15.6 2.4 1.5 1 0 0 1 1 1 1 Zinc ribbon domain zf-CRD PF17979.1 EMR68540.1 - 0.0087 16.2 0.9 0.011 15.9 0.9 1.1 1 0 0 1 1 1 1 Cysteine rich domain with multizinc binding regions GFA PF04828.14 EMR68540.1 - 0.0088 16.4 1.9 2.4 8.5 0.0 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_SprT PF17283.2 EMR68540.1 - 0.016 15.1 5.0 0.026 14.4 5.0 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zinc_ribbon_13 PF09855.9 EMR68540.1 - 0.035 14.3 0.8 0.82 9.9 0.2 2.1 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf_UBZ PF18439.1 EMR68540.1 - 0.04 13.5 3.6 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 EMR68540.1 - 0.082 12.8 3.2 3.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-ISL3 PF14690.6 EMR68540.1 - 0.1 13.2 5.4 0.22 12.2 1.4 2.1 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2 PF00096.26 EMR68540.1 - 0.53 10.8 5.1 1.2 9.7 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.12 EMR68540.1 - 0.54 9.8 7.7 2.8 7.5 0.5 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.6 EMR68540.1 - 3.1 8.4 8.9 10 6.7 0.4 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain adh_short_C2 PF13561.6 EMR68541.1 - 1.3e-56 191.7 0.2 1.6e-56 191.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR68541.1 - 1.8e-45 154.8 0.1 2.3e-45 154.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR68541.1 - 4.5e-09 36.5 0.0 6.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 EMR68541.1 - 0.0021 18.2 0.4 0.0029 17.7 0.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 EMR68541.1 - 0.0074 15.6 0.5 0.015 14.6 0.5 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.22 EMR68542.1 - 9.2e-06 24.7 0.0 1e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 EMR68542.1 - 0.001 18.9 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 TUP1-like enhancer of split AAA PF00004.29 EMR68543.1 - 1.6e-21 77.1 0.0 3.5e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMR68543.1 - 0.0002 21.2 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EMR68543.1 - 0.0082 15.9 0.3 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain TIP49 PF06068.13 EMR68543.1 - 0.051 12.8 0.1 4.6 6.3 0.0 2.2 1 1 1 2 2 2 0 TIP49 P-loop domain Vps4_C PF09336.10 EMR68543.1 - 0.061 13.3 0.1 0.58 10.2 0.0 2.6 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain HIT PF01230.23 EMR68544.1 - 9e-17 61.6 0.0 1.3e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EMR68544.1 - 0.00028 21.3 0.0 0.00044 20.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2267 PF10025.9 EMR68544.1 - 0.008 16.4 1.5 0.14 12.5 0.2 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) CwfJ_C_1 PF04677.15 EMR68544.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 EMR68544.1 - 0.16 11.6 0.0 0.44 10.2 0.0 1.6 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain GMC_oxred_N PF00732.19 EMR68545.1 - 8.4e-52 176.4 0.0 9.3e-51 172.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EMR68545.1 - 6.4e-05 22.3 0.4 0.04 13.2 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR68545.1 - 0.00019 20.6 0.0 0.00052 19.2 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMR68545.1 - 0.0017 18.5 0.1 0.0036 17.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR68545.1 - 0.0025 17.1 0.1 0.85 8.8 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR68545.1 - 0.011 16.3 0.2 0.36 11.4 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMR68545.1 - 0.012 14.8 0.2 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EMR68545.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 EMR68545.1 - 0.024 14.2 0.9 0.086 12.4 0.8 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR68545.1 - 0.045 12.5 0.2 1.4 7.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 EMR68545.1 - 0.058 12.2 0.2 0.086 11.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 EMR68545.1 - 0.19 12.0 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain APH PF01636.23 EMR68547.1 - 7.8e-06 26.0 0.1 1.3e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Beta-lactamase PF00144.24 EMR68549.1 - 1.9e-38 132.5 0.1 1e-37 130.2 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase PsbX PF06596.11 EMR68550.1 - 0.53 10.3 2.9 1.4 9.0 2.9 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) FMO-like PF00743.19 EMR68551.1 - 2e-16 59.5 0.3 3.1e-14 52.3 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMR68551.1 - 3.6e-13 49.4 0.0 1.3e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR68551.1 - 2.9e-09 36.5 0.0 1.6e-08 34.1 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMR68551.1 - 2.8e-08 33.4 0.0 8.1e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR68551.1 - 2.9e-07 30.6 0.7 4.3e-06 26.9 0.4 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMR68551.1 - 0.025 14.6 3.1 11 5.9 0.1 4.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMR68551.1 - 0.028 15.0 0.5 8.5 7.0 0.3 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR68551.1 - 0.072 12.2 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EMR68551.1 - 0.16 11.5 0.6 1.3 8.5 0.1 2.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR68551.1 - 0.28 9.8 2.8 0.33 9.6 0.2 2.3 3 0 0 3 3 3 0 HI0933-like protein MFS_1 PF07690.16 EMR68552.1 - 3.9e-33 114.8 26.6 3.6e-27 95.2 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR68552.1 - 2.5e-11 43.1 1.5 2.5e-11 43.1 1.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EMR68552.1 - 0.078 11.4 7.7 0.42 9.0 2.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector AAA PF00004.29 EMR68553.1 - 2.1e-24 86.4 0.0 4.3e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 EMR68553.1 - 5.3e-23 82.0 0.0 9.8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.12 EMR68553.1 - 2.5e-07 30.6 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EMR68553.1 - 0.0023 17.5 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMR68553.1 - 0.0035 17.3 0.0 0.61 10.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EMR68553.1 - 0.0086 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EMR68553.1 - 0.019 15.3 0.0 0.076 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EMR68553.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein IPT PF01745.16 EMR68553.1 - 0.022 14.1 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase Parvo_NS1 PF01057.17 EMR68553.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TACC_C PF05010.14 EMR68554.1 - 0.01 15.7 10.2 0.01 15.7 10.2 6.6 4 3 1 5 5 5 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1110 PF06533.12 EMR68554.1 - 0.03 14.3 1.0 0.03 14.3 1.0 4.2 4 2 3 7 7 7 0 Protein of unknown function (DUF1110) Filament PF00038.21 EMR68554.1 - 0.072 12.7 89.5 0.024 14.2 11.1 6.7 4 2 4 8 8 8 0 Intermediate filament protein ANAPC_CDC26 PF10471.9 EMR68555.1 - 1.2 10.0 10.5 2.7 8.9 2.8 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 PepSY_TM PF03929.16 EMR68556.1 - 0.0099 15.6 0.0 0.011 15.4 0.0 1.0 1 0 0 1 1 1 1 PepSY-associated TM region Adeno_E3_CR2 PF02439.15 EMR68556.1 - 3.4 7.5 6.6 5.5 6.8 6.6 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 EMR68559.1 - 6.2e-23 81.5 0.0 9.7e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EMR68559.1 - 4.3e-10 40.0 8.0 4.3e-07 30.5 0.2 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.22 EMR68559.1 - 1.3e-08 34.3 9.0 1.1 9.6 0.0 6.8 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.17 EMR68559.1 - 3.8e-05 23.1 0.0 5.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EMR68559.1 - 0.002 18.5 6.6 0.61 10.5 0.0 5.4 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 EMR68559.1 - 0.023 14.7 0.9 4.7 7.2 0.0 3.4 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EMR68559.1 - 0.024 15.1 1.8 0.59 10.7 0.2 3.8 3 0 0 3 3 3 0 HEAT-like repeat LapA_dom PF06305.11 EMR68560.1 - 0.16 11.8 0.1 0.36 10.7 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Ribonucleas_3_3 PF14622.6 EMR68561.1 - 1.4e-06 28.5 0.0 0.0039 17.3 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EMR68561.1 - 0.00023 21.7 0.1 0.0012 19.5 0.1 2.1 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EMR68561.1 - 0.00029 21.5 0.0 0.00062 20.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif PLA2_B PF01735.18 EMR68562.1 - 2.5e-29 102.0 0.0 4.4e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Borrelia_P83 PF05262.11 EMR68562.1 - 0.16 10.4 4.7 0.22 10.0 4.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 EMR68562.1 - 0.54 9.0 2.6 0.73 8.5 2.6 1.3 1 0 0 1 1 1 0 Presenilin ADH_N_2 PF16884.5 EMR68563.1 - 3.3e-29 100.9 0.0 5.9e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EMR68563.1 - 6e-17 61.8 0.5 9.8e-17 61.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR68563.1 - 5.2e-10 40.5 0.4 1.2e-09 39.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SH3_9 PF14604.6 EMR68564.1 - 9.2e-06 25.4 0.1 2.1e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMR68564.1 - 0.00013 21.5 0.1 0.00027 20.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SARAF PF06682.12 EMR68564.1 - 0.00031 20.5 0.2 0.0006 19.6 0.2 1.4 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4690 PF15756.5 EMR68564.1 - 0.00095 19.7 0.4 0.0068 17.0 0.0 2.4 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 EMR68564.1 - 0.0054 17.0 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A EphA2_TM PF14575.6 EMR68564.1 - 0.033 15.1 0.0 0.096 13.6 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 EMR68564.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Syndecan PF01034.20 EMR68564.1 - 0.14 12.1 0.4 0.26 11.2 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Lactamase_B PF00753.27 EMR68565.1 - 3.6e-09 36.9 0.2 7e-06 26.2 0.1 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMR68565.1 - 0.00019 21.0 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DAO PF01266.24 EMR68566.1 - 2.8e-22 79.8 0.9 3.8e-22 79.3 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Birna_VP3 PF01767.16 EMR68567.1 - 1.8 8.6 5.1 17 5.4 3.9 2.3 2 0 0 2 2 2 0 Birnavirus VP3 protein PhyH PF05721.13 EMR68569.1 - 9.2e-06 26.1 0.0 3.3e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Prim_Zn_Ribbon PF08273.12 EMR68569.1 - 0.16 12.3 1.2 13 6.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase adh_short PF00106.25 EMR68570.1 - 1.2e-32 113.0 0.0 1.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68570.1 - 2.1e-24 86.4 0.0 3.7e-24 85.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68570.1 - 5.6e-14 52.5 0.0 7.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR68570.1 - 0.00045 19.8 0.0 0.00073 19.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMR68570.1 - 0.002 18.4 0.1 0.0067 16.7 0.1 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EMR68570.1 - 0.006 15.8 0.0 0.0078 15.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3458_C PF17432.2 EMR68570.1 - 0.093 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats Val_tRNA-synt_C PF10458.9 EMR68572.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Pkinase PF00069.25 EMR68572.1 - 0.056 12.8 0.0 0.087 12.2 0.0 1.3 1 1 0 1 1 1 0 Protein kinase domain Pinin_SDK_N PF04697.13 EMR68572.1 - 0.17 12.5 0.0 0.26 11.9 0.0 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region Mpv17_PMP22 PF04117.12 EMR68574.1 - 8.3e-17 61.2 0.4 8.3e-17 61.2 0.4 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family NRDD PF13597.6 EMR68574.1 - 0.072 11.9 0.1 0.097 11.4 0.1 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Ank_2 PF12796.7 EMR68575.1 - 8.8e-32 109.5 15.2 2.8e-05 24.6 0.0 11.5 10 2 2 12 12 12 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR68575.1 - 4e-13 49.3 9.1 1.4e-05 25.2 0.0 7.7 8 0 0 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR68575.1 - 2.7e-12 45.7 14.4 5.2 8.0 0.0 14.0 16 1 1 17 17 17 2 Ankyrin repeat Ank_4 PF13637.6 EMR68575.1 - 1.1e-11 45.0 11.6 0.077 13.6 0.0 10.8 11 3 2 13 13 13 1 Ankyrin repeats (many copies) Ank PF00023.30 EMR68575.1 - 2.6e-08 33.9 22.0 0.0039 17.6 0.0 12.3 14 0 0 14 14 14 1 Ankyrin repeat UDPGT PF00201.18 EMR68577.1 - 3.2e-07 29.5 0.0 4.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EMR68577.1 - 3.6e-05 23.8 0.0 5.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_hydro_61 PF03443.14 EMR68578.1 - 3.9e-51 173.9 0.1 4.5e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PLA2_B PF01735.18 EMR68578.1 - 0.02 13.3 0.1 0.027 12.9 0.1 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain zf-MYND PF01753.18 EMR68579.1 - 7.4e-10 38.8 10.3 7.4e-10 38.8 10.3 1.7 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EMR68579.1 - 0.046 14.0 7.5 0.17 12.2 7.5 2.1 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding FAD_binding_3 PF01494.19 EMR68580.1 - 4.3e-23 82.1 0.0 9e-23 81.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR68580.1 - 1.8e-09 37.7 3.4 0.00063 19.4 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR68580.1 - 6.5e-07 29.8 0.3 0.00018 22.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR68580.1 - 3e-06 26.7 0.1 0.00026 20.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR68580.1 - 5.6e-05 23.3 0.1 0.00012 22.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR68580.1 - 0.001 18.2 0.2 0.0055 15.8 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR68580.1 - 0.013 14.8 0.3 0.28 10.4 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR68580.1 - 0.015 14.4 0.6 0.7 8.9 0.9 2.7 2 1 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 EMR68580.1 - 0.021 13.5 0.7 0.37 9.4 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 EMR68580.1 - 0.033 13.5 0.4 10 5.2 0.0 3.4 3 1 1 4 4 4 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EMR68580.1 - 0.053 12.8 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EMR68580.1 - 0.13 11.3 0.3 0.22 10.5 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EMR68580.1 - 0.29 10.0 1.0 3.1 6.5 0.1 2.8 4 0 0 4 4 4 0 Tryptophan halogenase Esterase_phd PF10503.9 EMR68581.1 - 1.2e-05 24.9 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMR68581.1 - 9.1e-05 22.0 0.1 0.00072 19.1 0.1 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EMR68581.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 EMR68581.1 - 0.16 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Transferase PF02458.15 EMR68582.1 - 8.2e-19 67.6 0.0 1.2e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Transferase family Amidohydro_2 PF04909.14 EMR68583.1 - 1.3e-19 71.1 0.0 1.5e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 EMR68584.1 - 5.5e-28 97.9 30.6 6.9e-20 71.3 11.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR68584.1 - 1.8e-05 23.8 9.8 2.8e-05 23.2 9.8 1.3 1 0 0 1 1 1 1 MFS_1 like family NAD_binding_10 PF13460.6 EMR68586.1 - 6.1e-24 84.9 0.0 5.9e-22 78.5 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR68586.1 - 2e-05 24.3 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 EMR68586.1 - 0.12 13.0 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 EMR68586.1 - 0.18 11.2 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EMR68588.1 - 1.9e-12 47.7 0.0 4.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR68588.1 - 1.3e-09 38.5 0.0 4.8e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR68588.1 - 1.9e-08 34.9 0.0 3.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR68588.1 - 5.4e-05 23.1 0.0 7.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMR68588.1 - 0.00069 19.1 0.0 0.00091 18.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EMR68588.1 - 0.00081 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR68588.1 - 0.0011 18.3 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMR68588.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 EMR68588.1 - 0.0015 18.1 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.11 EMR68588.1 - 0.0057 16.3 0.0 0.0081 15.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) UPF0020 PF01170.18 EMR68588.1 - 0.09 12.4 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Pyr_redox_3 PF13738.6 EMR68589.1 - 2.4e-14 53.3 0.0 8.5e-14 51.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMR68589.1 - 3.3e-14 52.2 0.0 3.7e-08 32.3 0.0 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMR68589.1 - 3.7e-07 29.7 0.0 1.5e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR68589.1 - 2.9e-06 26.7 0.0 1.2e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMR68589.1 - 1e-05 25.6 0.0 0.066 13.2 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 EMR68589.1 - 1.3e-05 24.6 0.0 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 EMR68589.1 - 5.2e-05 23.4 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMR68589.1 - 0.00091 18.0 0.0 0.32 9.7 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 EMR68589.1 - 0.0042 17.6 0.1 8.3 7.1 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR68589.1 - 0.063 12.9 0.0 1.6 8.2 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase AA_permease PF00324.21 EMR68590.1 - 6.5e-125 417.4 39.5 7.4e-125 417.2 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR68590.1 - 7.4e-38 130.5 46.9 9.1e-38 130.2 46.9 1.1 1 0 0 1 1 1 1 Amino acid permease ketoacyl-synt PF00109.26 EMR68593.1 - 5.1e-72 242.5 0.0 9.8e-72 241.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EMR68593.1 - 3.2e-62 210.5 0.1 5.4e-62 209.7 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EMR68593.1 - 1.6e-58 197.6 4.3 9e-58 195.1 0.6 3.2 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 EMR68593.1 - 2.9e-45 155.2 0.0 5.6e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR68593.1 - 6.5e-32 110.0 0.1 2.4e-31 108.2 0.1 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR68593.1 - 4.4e-16 59.3 0.0 1.8e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EMR68593.1 - 1.7e-08 34.2 0.1 4.7e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68593.1 - 1.3e-07 31.4 0.9 2.3e-07 30.6 0.2 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EMR68593.1 - 5.3e-05 22.7 0.1 0.00011 21.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EMR68593.1 - 0.0011 19.2 0.0 0.0026 18.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 EMR68593.1 - 0.0029 17.4 0.8 0.13 12.2 0.2 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1656 PF07869.12 EMR68594.1 - 1.3 9.1 8.8 0.17 11.9 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Acetyltransf_7 PF13508.7 EMR68595.1 - 2.9e-06 27.6 0.1 3.7e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR68595.1 - 5.2e-05 23.2 0.0 7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR68595.1 - 0.0007 19.8 0.2 0.00092 19.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMR68595.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein SET PF00856.28 EMR68597.1 - 3.7e-11 43.7 0.0 5.9e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 SET domain CRC_subunit PF08624.10 EMR68598.1 - 6.6e-54 182.0 0.3 1.2e-53 181.1 0.0 1.6 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Ank_2 PF12796.7 EMR68599.1 - 7.2e-06 26.5 0.0 0.0069 17.0 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Acetyltransf_7 PF13508.7 EMR68599.1 - 0.00089 19.6 0.0 0.015 15.7 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR68599.1 - 0.00091 19.2 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR68599.1 - 0.0036 17.5 0.1 0.027 14.7 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family AAA PF00004.29 EMR68600.1 - 1.1e-17 64.7 0.0 2e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 EMR68600.1 - 0.00085 19.0 0.0 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 EMR68600.1 - 0.0053 17.1 0.2 0.0053 17.1 0.2 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EMR68600.1 - 0.017 15.4 0.1 0.11 12.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMR68600.1 - 0.042 14.0 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMR68600.1 - 0.14 12.2 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glyco_hydro_3_C PF01915.22 EMR68602.1 - 3.1e-49 167.7 0.0 5.9e-49 166.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR68602.1 - 4e-38 131.6 0.0 7.2e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR68602.1 - 5.6e-17 61.6 0.1 1.1e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3237 PF11578.8 EMR68603.1 - 6.7e-21 74.7 0.0 7e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GXWXG PF14231.6 EMR68603.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 GXWXG protein HRI1 PF16815.5 EMR68604.1 - 4.3e-71 239.3 0.1 4.9e-71 239.1 0.1 1.0 1 0 0 1 1 1 1 Protein HRI1 SUIM_assoc PF16619.5 EMR68605.1 - 0.53 10.4 6.5 0.92 9.6 6.5 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Glft2_N PF17994.1 EMR68606.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Galactofuranosyltransferase 2 N-terminal zf-rbx1 PF12678.7 EMR68607.1 - 6.2e-07 29.6 0.3 1.2e-06 28.7 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EMR68607.1 - 4.3e-06 27.0 0.7 1.2e-05 25.6 0.7 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EMR68607.1 - 6.3e-06 26.1 0.3 1.3e-05 25.1 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMR68607.1 - 0.00018 21.3 0.1 0.00036 20.3 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EMR68607.1 - 0.0013 18.3 0.0 0.0037 16.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EMR68607.1 - 0.002 18.1 0.1 0.0046 17.0 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EMR68607.1 - 0.036 14.3 0.3 0.067 13.4 0.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EMR68607.1 - 0.039 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EMR68607.1 - 0.061 13.1 2.8 0.57 10.0 2.8 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 EMR68607.1 - 0.15 12.1 0.6 0.63 10.0 0.7 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMR68607.1 - 0.31 10.9 1.5 0.48 10.3 0.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hce2 PF14856.6 EMR68608.1 - 2e-09 37.7 0.1 2.4e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor OPT PF03169.15 EMR68609.1 - 7.2e-153 510.5 52.9 8.3e-153 510.3 52.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PhoD PF09423.10 EMR68610.1 - 5.8e-43 147.2 0.0 1.1e-42 146.4 0.0 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S10 PF00450.22 EMR68612.1 - 1.5e-96 324.4 0.1 1.8e-96 324.2 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase GMC_oxred_N PF00732.19 EMR68613.1 - 7.2e-35 120.8 0.0 1.4e-33 116.6 0.0 2.1 1 1 1 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR68613.1 - 4.6e-27 95.3 0.1 1e-26 94.2 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EMR68613.1 - 3.5e-05 23.2 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR68613.1 - 0.0041 17.3 0.1 0.0089 16.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR68613.1 - 0.0051 16.0 0.6 0.57 9.2 1.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EMR68613.1 - 0.0051 16.1 0.2 1.9 7.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR68613.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Ank_2 PF12796.7 EMR68614.1 - 9e-67 221.7 5.3 6.1e-10 39.6 0.2 7.7 4 2 6 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR68614.1 - 1.3e-44 150.0 12.4 7.9e-07 29.5 0.0 11.2 5 4 8 14 14 14 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR68614.1 - 6e-40 134.8 8.7 8.1e-08 32.4 0.0 10.2 5 4 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EMR68614.1 - 8.8e-37 124.0 27.2 2.2e-05 24.7 0.0 14.4 14 1 0 14 14 14 9 Ankyrin repeat Ank_3 PF13606.6 EMR68614.1 - 6.4e-34 112.2 19.7 2.9e-06 27.2 0.0 14.2 16 0 0 16 16 16 8 Ankyrin repeat MapZ_C2 PF18708.1 EMR68614.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 MapZ extracellular C-terminal domain 2 Abhydrolase_3 PF07859.13 EMR68615.1 - 2.6e-05 24.2 0.8 0.022 14.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR68615.1 - 0.009 15.3 0.0 0.02 14.2 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 EMR68615.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Thioesterase PF00975.20 EMR68615.1 - 0.016 15.3 0.1 0.026 14.6 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 EMR68615.1 - 0.19 11.3 0.1 0.28 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EMR68615.1 - 1.2 9.7 18.8 1.7 9.2 18.8 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family SKIP_SNW PF02731.15 EMR68617.1 - 9e-71 236.7 7.0 9e-71 236.7 7.0 2.5 2 0 0 2 2 2 1 SKIP/SNW domain EMP24_GP25L PF01105.24 EMR68617.1 - 1.3e-45 155.6 2.4 3.2e-45 154.3 2.4 1.7 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4603 PF15376.6 EMR68617.1 - 1.3 6.4 18.5 1.9 5.7 18.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) AXE1 PF05448.12 EMR68618.1 - 1.3e-09 37.2 0.0 0.00016 20.5 0.0 3.0 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 EMR68618.1 - 5.9e-09 35.9 0.0 1.2e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EMR68618.1 - 8.2e-09 36.4 0.1 1.1e-08 36.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EMR68618.1 - 7.5e-08 32.1 0.0 2.9e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EMR68618.1 - 2e-06 27.7 0.0 2.7e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR68618.1 - 0.00015 21.1 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 EMR68618.1 - 0.00042 20.3 0.0 0.0061 16.5 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 EMR68618.1 - 0.0064 16.2 0.0 0.029 14.0 0.0 1.9 1 1 0 1 1 1 1 Putative esterase SKG6 PF08693.10 EMR68619.1 - 0.015 14.7 0.1 0.036 13.5 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 EMR68619.1 - 0.15 12.0 1.8 0.48 10.4 1.8 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Cwf_Cwc_15 PF04889.12 EMR68619.1 - 1.6 8.4 9.9 2.5 7.8 9.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EMR68619.1 - 8.6 6.8 10.4 19 5.7 10.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Mito_carr PF00153.27 EMR68621.1 - 1.6e-71 236.3 0.5 6.2e-25 87.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EMR68621.1 - 5.1e-15 55.7 2.4 5.3e-07 30.0 0.6 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EMR68621.1 - 5.6e-14 50.6 4.9 1.4e-06 27.4 0.2 6.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EMR68621.1 - 9.8e-14 50.0 0.6 3.2e-06 26.6 0.1 5.6 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.6 EMR68621.1 - 1.9e-08 34.0 2.0 0.072 12.9 0.0 5.8 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EMR68621.1 - 4.5e-07 29.1 0.3 0.00022 20.5 0.2 3.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EMR68621.1 - 0.11 12.9 0.0 1.3e+02 2.9 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain Serine_protease PF18405.1 EMR68621.1 - 0.19 10.8 0.6 6.5 5.8 0.1 2.9 2 1 2 4 4 4 0 Gammaproteobacterial serine protease NAD_binding_10 PF13460.6 EMR68622.1 - 6e-15 55.6 0.0 1.2e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR68622.1 - 1.3e-13 51.1 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR68622.1 - 5.6e-05 22.7 0.0 8.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EMR68622.1 - 0.0003 21.2 0.2 0.00055 20.4 0.2 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EMR68622.1 - 0.001 19.2 0.2 0.003 17.7 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 EMR68622.1 - 0.0012 18.9 0.2 0.0019 18.3 0.2 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 EMR68622.1 - 0.012 14.7 0.1 0.025 13.7 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.19 EMR68622.1 - 0.015 14.3 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EMR68622.1 - 0.023 14.6 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EMR68622.1 - 0.092 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CoA_binding PF02629.19 EMR68622.1 - 0.13 13.0 0.3 0.36 11.6 0.3 1.7 1 0 0 1 1 1 0 CoA binding domain Sugar_tr PF00083.24 EMR68624.1 - 1.2e-76 258.5 21.6 1.4e-76 258.2 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR68624.1 - 7.4e-22 77.8 34.6 7.7e-18 64.5 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.19 EMR68625.1 - 0.022 15.2 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box F-box PF00646.33 EMR68626.1 - 0.042 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 F-box domain AnmK PF03702.14 EMR68627.1 - 2.8e-85 286.6 0.0 3.3e-85 286.4 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FMN_red PF03358.15 EMR68628.1 - 3.6e-20 72.3 0.0 4.9e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMR68628.1 - 2.5e-05 24.1 0.0 4.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Coatomer_WDAD PF04053.14 EMR68629.1 - 0.23 10.4 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Vps39_1 PF10366.9 EMR68630.1 - 6.6e-29 100.4 0.0 5.5e-21 74.9 0.0 3.9 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 EMR68630.1 - 1.1e-14 54.7 0.0 4.2e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 EMR68630.1 - 8.2e-11 42.3 0.0 2.6e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 TPR_1 PF00515.28 EMR68630.1 - 0.0014 18.4 3.2 6.8 6.7 1.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMR68630.1 - 0.0016 18.3 0.9 2.8 8.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR68630.1 - 0.0019 18.2 0.9 59 4.1 0.3 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMR68630.1 - 0.0062 17.0 0.0 3.5 8.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR68630.1 - 0.031 14.9 0.1 1.1 10.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMR68630.1 - 0.073 13.4 4.0 5.9 7.3 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.20 EMR68630.1 - 0.25 11.2 0.7 1.7 8.5 0.1 2.5 3 0 0 3 3 3 0 Region in Clathrin and VPS PI3K_1B_p101 PF10486.9 EMR68630.1 - 0.36 8.5 7.9 0.69 7.6 7.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1115 PF06544.12 EMR68630.1 - 4.2 7.5 4.9 0.5 10.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) Amidohydro_3 PF07969.11 EMR68631.1 - 7.7e-14 52.0 0.8 2.6e-06 27.2 0.0 3.1 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_1 PF01979.20 EMR68631.1 - 1.7e-11 44.0 3.1 2.5e-08 33.6 0.1 4.0 3 1 0 3 3 3 2 Amidohydrolase family NAD_binding_2 PF03446.15 EMR68633.1 - 1.5e-24 87.0 1.1 2.5e-24 86.2 1.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMR68633.1 - 4.4e-23 81.8 0.2 2.7e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Lactamase_B_2 PF12706.7 EMR68633.1 - 0.0012 18.4 0.0 0.004 16.7 0.0 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMR68633.1 - 0.0013 18.7 4.0 0.0041 17.1 4.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EMR68633.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CMD PF02627.20 EMR68634.1 - 4.4e-19 68.3 0.1 7.6e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TFX_C PF14601.6 EMR68634.1 - 0.031 14.3 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term PPTA PF01239.22 EMR68635.1 - 9.2e-40 133.3 14.8 7.2e-09 35.1 1.6 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Mucin PF01456.17 EMR68635.1 - 0.64 10.0 14.7 1 9.4 14.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ank_2 PF12796.7 EMR68636.1 - 2.4e-13 50.5 0.0 1.6e-09 38.2 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR68636.1 - 3e-09 37.2 0.0 2.2e-05 24.9 0.0 3.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR68636.1 - 6e-08 32.8 0.1 1.2e-06 28.6 0.0 3.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR68636.1 - 9.5e-08 31.7 0.1 0.93 10.3 0.0 5.4 5 1 1 6 6 6 2 Ankyrin repeat Ank PF00023.30 EMR68636.1 - 0.0019 18.6 0.0 0.24 11.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat SPX PF03105.19 EMR68637.1 - 7.9e-44 151.1 0.3 6.5e-31 108.6 0.1 2.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 EMR68637.1 - 1.4e-34 119.9 33.2 2e-34 119.4 33.2 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EMR68637.1 - 1e-27 97.1 33.6 2.2e-27 96.1 33.6 1.5 1 0 0 1 1 1 1 Citrate transporter FTA2 PF13095.6 EMR68637.1 - 2.4e-06 27.3 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 PBP1_TM PF14812.6 EMR68637.1 - 0.0069 16.7 1.4 0.0069 16.7 1.4 2.5 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 EMR68637.1 - 7.5 6.8 7.0 3 8.1 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MFS_1 PF07690.16 EMR68638.1 - 5.4e-27 94.6 32.2 6.6e-27 94.4 30.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.9 EMR68638.1 - 0.12 12.6 0.2 0.56 10.4 0.2 2.2 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1230 PF06799.11 EMR68638.1 - 0.49 10.5 2.6 0.53 10.4 0.3 2.1 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 NmrA PF05368.13 EMR68639.1 - 8.3e-27 94.2 0.3 2e-26 93.0 0.3 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR68639.1 - 3.1e-14 53.3 0.9 2.8e-13 50.2 0.9 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EMR68639.1 - 0.00021 21.7 0.4 0.00043 20.7 0.4 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EMR68639.1 - 0.0008 18.9 0.2 0.0019 17.7 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EMR68639.1 - 0.0039 17.3 0.6 0.0081 16.3 0.6 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EMR68639.1 - 0.0057 16.9 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EMR68639.1 - 0.031 13.4 0.1 0.049 12.8 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein MCR_beta_N PF02783.15 EMR68639.1 - 0.059 13.0 0.7 5.6 6.6 0.1 3.0 3 0 0 3 3 3 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Peptidase_M20 PF01546.28 EMR68640.1 - 1.1e-27 97.1 0.0 1.6e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR68640.1 - 1.7e-05 24.7 0.0 4.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMR68640.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 RNase_H PF00075.24 EMR68641.1 - 1.8e-14 54.1 0.0 3.9e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 RNase H Hva1_TUDOR PF11160.8 EMR68641.1 - 0.27 11.4 3.8 0.19 11.9 1.4 2.0 2 0 0 2 2 2 0 Hypervirulence associated proteins TUDOR domain HbrB PF08539.11 EMR68643.1 - 1.2e-47 162.1 0.0 1.2e-47 162.1 0.0 2.3 2 0 0 2 2 2 1 HbrB-like Activator_LAG-3 PF11498.8 EMR68643.1 - 0.37 9.7 31.8 0.77 8.7 31.8 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Presenilin PF01080.17 EMR68643.1 - 0.72 8.6 5.6 1.3 7.7 5.6 1.4 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 EMR68643.1 - 1.8 8.1 26.8 3.3 7.3 26.8 1.3 1 0 0 1 1 1 0 Spt20 family ABC_tran PF00005.27 EMR68644.1 - 3.1e-29 102.2 0.1 5.4e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMR68644.1 - 2.3e-06 27.2 1.6 0.0002 20.9 0.2 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EMR68644.1 - 0.00011 22.4 0.6 0.00023 21.3 0.6 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 EMR68644.1 - 0.00056 20.3 0.1 0.0012 19.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR68644.1 - 0.00093 19.5 0.0 0.022 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EMR68644.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EMR68644.1 - 0.0024 18.0 0.1 0.0059 16.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EMR68644.1 - 0.02 14.6 0.1 0.6 9.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.7 EMR68644.1 - 0.023 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.6 EMR68644.1 - 0.025 14.7 0.6 0.15 12.2 0.6 2.2 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 EMR68644.1 - 0.031 13.9 0.2 0.04 13.6 0.2 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region DEAD PF00270.29 EMR68644.1 - 0.034 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 EMR68644.1 - 0.039 13.7 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EMR68644.1 - 0.039 14.5 0.0 0.073 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EMR68644.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.6 EMR68644.1 - 0.11 12.3 0.0 1.4 8.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EMR68644.1 - 0.11 12.2 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EMR68644.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 EMR68644.1 - 0.13 11.1 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 EMR68644.1 - 0.13 12.6 0.3 1.4 9.3 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EMR68644.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 EMR68644.1 - 0.17 11.0 0.3 1.1 8.4 0.1 2.2 3 0 0 3 3 3 0 NB-ARC domain Atg8 PF02991.16 EMR68645.1 - 2.9e-51 172.0 0.2 3.4e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EMR68645.1 - 3.2e-06 27.4 0.0 3.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pkinase PF00069.25 EMR68646.1 - 0.00012 21.6 0.0 0.029 13.8 0.0 3.1 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR68646.1 - 0.036 13.4 0.0 1.9 7.7 0.0 3.0 3 1 1 4 4 4 0 Protein tyrosine kinase MFS_1 PF07690.16 EMR68648.1 - 3.3e-16 59.2 18.8 2e-09 36.8 6.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 EMR68648.1 - 0.0067 14.8 3.3 0.023 13.0 1.0 2.3 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family RseC_MucC PF04246.12 EMR68648.1 - 0.072 13.0 3.0 1.4 8.9 0.1 2.8 2 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC LIM_bind PF01803.16 EMR68649.1 - 3.5e-54 183.9 0.1 3.5e-54 183.9 0.1 3.1 2 1 1 3 3 3 1 LIM-domain binding protein HCV_NS5a_1b PF08301.13 EMR68650.1 - 0.17 12.5 0.3 4.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b Gon7 PF08738.10 EMR68651.1 - 8.4e-10 38.7 0.2 2.8e-09 37.0 0.1 1.8 1 1 1 2 2 2 1 Gon7 family ADH_N PF08240.12 EMR68652.1 - 8.3e-18 64.3 0.0 3.4e-17 62.3 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR68652.1 - 7.8e-16 58.2 0.4 1.3e-15 57.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 EMR68652.1 - 0.023 14.5 0.1 0.048 13.4 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EMR68652.1 - 0.086 13.6 0.1 0.21 12.3 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_2 PF03446.15 EMR68653.1 - 9.4e-22 77.9 0.0 1.3e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMR68653.1 - 1.9e-21 76.5 0.1 3.5e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Menin PF05053.13 EMR68653.1 - 0.091 11.1 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Menin Methyltransf_2 PF00891.18 EMR68654.1 - 8.8e-24 84.0 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EMR68654.1 - 7.6e-06 25.8 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_25 PF13649.6 EMR68654.1 - 0.0044 17.7 0.0 0.016 15.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR68654.1 - 0.035 13.9 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DEC-1_N PF04625.13 EMR68655.1 - 0.029 13.4 4.2 0.033 13.2 4.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CMD PF02627.20 EMR68656.1 - 1.7e-06 28.0 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family MAF_flag10 PF01973.18 EMR68656.1 - 0.013 15.3 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF115 Caps_synth PF05704.12 EMR68657.1 - 2.2e-11 43.7 0.0 3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 EMR68657.1 - 3.3e-07 30.9 0.1 6.1e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EMR68657.1 - 0.21 10.8 0.1 0.3 10.3 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DEAD PF00270.29 EMR68658.1 - 2.9e-22 79.3 0.0 2.4e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR68658.1 - 1e-19 70.9 0.0 2e-17 63.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR68658.1 - 2.4e-05 24.4 0.0 4.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 EMR68658.1 - 0.0089 16.7 0.1 0.024 15.4 0.1 1.7 1 0 0 1 1 1 1 RecQ zinc-binding SNF2_N PF00176.23 EMR68658.1 - 0.028 13.1 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Thioredoxin_8 PF13905.6 EMR68658.1 - 0.12 12.7 0.1 2 8.8 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin-like GRP PF07172.11 EMR68658.1 - 6.6 7.5 14.4 17 6.1 14.4 1.7 1 0 0 1 1 1 0 Glycine rich protein family ECH_1 PF00378.20 EMR68659.1 - 1.7e-26 93.1 0.1 1.8e-25 89.7 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMR68659.1 - 9.3e-15 54.9 0.0 1.2e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Methyltransf_23 PF13489.6 EMR68660.1 - 4.4e-20 72.2 0.0 7.6e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR68660.1 - 1.2e-11 45.2 0.0 4.5e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR68660.1 - 9.4e-10 39.0 0.0 2.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR68660.1 - 5.2e-08 33.5 0.0 1e-06 29.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR68660.1 - 7.6e-07 29.0 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EMR68660.1 - 6e-05 22.5 0.0 0.038 13.3 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EMR68660.1 - 0.0054 16.5 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EMR68660.1 - 0.0085 15.7 0.0 0.028 14.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EMR68660.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EMR68660.1 - 0.055 12.7 0.0 0.32 10.2 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EMR68660.1 - 0.12 11.8 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 EMR68660.1 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Vps51 PF08700.11 EMR68661.1 - 1.1e-14 54.3 0.0 5.3e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 MutS_III PF05192.18 EMR68661.1 - 0.017 15.4 0.0 0.21 11.8 0.1 2.4 2 2 0 2 2 2 0 MutS domain III TraH_2 PF06871.11 EMR68661.1 - 0.12 12.0 0.5 0.23 11.1 0.5 1.3 1 0 0 1 1 1 0 TraH_2 PP2C PF00481.21 EMR68662.1 - 4.3e-31 108.5 0.0 2.1e-30 106.3 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EMR68662.1 - 8.9e-05 22.5 0.1 0.62 9.9 0.0 2.8 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) DUF3439 PF11921.8 EMR68662.1 - 0.032 14.2 0.4 0.082 12.9 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DHQ_synthase PF01761.20 EMR68663.1 - 5.8e-73 245.3 0.0 2e-63 214.0 0.0 2.4 2 0 0 2 2 2 2 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EMR68663.1 - 1.4e-10 41.3 0.1 0.00013 21.8 0.0 2.9 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase Epimerase PF01370.21 EMR68663.1 - 1.8e-10 40.7 0.0 1.2e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 EMR68663.1 - 3.8e-10 39.6 0.1 1.1e-09 38.1 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 EMR68663.1 - 2.3e-07 30.5 0.0 0.00051 19.5 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase ROK PF00480.20 EMR68663.1 - 4.7e-07 29.6 0.0 2.5e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 ROK family Fe-ADH PF00465.19 EMR68663.1 - 1.8e-06 27.1 0.0 0.0083 15.0 0.1 3.3 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase ADH_zinc_N PF00107.26 EMR68663.1 - 2.4e-06 27.5 0.6 8.4e-06 25.8 0.6 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 EMR68663.1 - 3.6e-05 23.9 0.0 0.0024 17.9 0.1 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EMR68663.1 - 0.00013 21.7 0.1 0.92 9.1 0.1 3.3 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 EMR68663.1 - 0.0084 15.6 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus RmlD_sub_bind PF04321.17 EMR68663.1 - 0.029 13.5 0.0 0.54 9.3 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain ThiF PF00899.21 EMR68663.1 - 0.065 12.6 0.6 1.6 8.0 0.1 2.4 2 0 0 2 2 2 0 ThiF family adh_short PF00106.25 EMR68663.1 - 0.083 12.3 0.3 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Alpha_Helical PF18489.1 EMR68663.1 - 0.088 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha helical domain Pyr_redox_2 PF07992.14 EMR68663.1 - 0.096 11.9 0.2 1.9 7.6 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EMR68663.1 - 0.1 13.0 0.3 0.3 11.5 0.3 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Bacteriocin_IIc PF10439.9 EMR68663.1 - 0.15 12.2 1.7 0.45 10.7 1.7 1.8 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide NAD_binding_10 PF13460.6 EMR68663.1 - 0.16 11.8 0.7 0.72 9.7 0.0 2.5 2 0 0 2 2 2 0 NAD(P)H-binding FAD_binding_3 PF01494.19 EMR68663.1 - 0.97 8.6 2.7 3.9 6.6 0.2 2.5 3 0 0 3 3 3 0 FAD binding domain SesA PF17107.5 EMR68665.1 - 0.00013 22.1 0.4 0.00029 21.0 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 EMR68665.1 - 0.12 12.8 2.1 14 6.3 0.2 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DbpA PF03880.15 EMR68665.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Fructosamin_kin PF03881.14 EMR68666.1 - 9.7e-61 205.5 0.0 1.2e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase ATP-grasp_2 PF08442.10 EMR68667.1 - 1.2e-64 217.6 1.9 1.2e-64 217.6 0.3 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EMR68667.1 - 1.1e-26 93.5 0.5 2.2e-26 92.5 0.5 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EMR68667.1 - 3.7e-05 23.3 0.3 8.1e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EMR68667.1 - 0.0012 18.7 1.0 0.047 13.5 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 EMR68667.1 - 0.15 12.3 0.1 1.4 9.2 0.0 2.5 3 1 1 4 4 4 0 Orn/Lys/Arg decarboxylase, N-terminal domain LPD22 PF18834.1 EMR68667.1 - 0.16 12.2 0.2 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 Glyco_hydro_15 PF00723.21 EMR68668.1 - 3.1e-98 329.5 0.3 3.8e-98 329.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EMR68668.1 - 1.4e-33 114.6 1.8 3.5e-33 113.4 1.8 1.7 1 0 0 1 1 1 1 Starch binding domain KR PF08659.10 EMR68669.1 - 1.1e-40 139.5 5.2 2.1e-21 76.6 0.5 3.0 2 1 1 3 3 3 2 KR domain ADH_zinc_N_2 PF13602.6 EMR68669.1 - 7.5e-18 65.9 0.0 2.5e-17 64.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR68669.1 - 1.2e-16 60.9 0.0 4.9e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EMR68669.1 - 1.3e-08 35.1 0.1 2.9e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EMR68669.1 - 1.6e-07 31.2 0.0 3.9e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EMR68669.1 - 0.016 14.6 0.1 0.016 14.6 0.1 2.9 3 0 0 3 3 3 0 short chain dehydrogenase SART-1 PF03343.13 EMR68670.1 - 4.3e-179 597.1 65.0 5.1e-179 596.8 65.0 1.0 1 0 0 1 1 1 1 SART-1 family Abhydrolase_6 PF12697.7 EMR68671.1 - 4.3e-14 53.6 0.0 5e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EMR68671.1 - 0.00066 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase CPT PF07931.12 EMR68672.1 - 0.00037 20.4 0.0 0.00063 19.6 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 EMR68672.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 EMR68672.1 - 0.015 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMR68672.1 - 0.037 14.6 0.0 0.06 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR68672.1 - 0.093 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CoaE PF01121.20 EMR68672.1 - 0.1 12.3 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase Zeta_toxin PF06414.12 EMR68672.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 EMR68672.1 - 0.21 11.8 0.0 0.47 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain ADH_N PF08240.12 EMR68673.1 - 1.1e-23 83.1 2.3 1.8e-23 82.5 2.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR68673.1 - 1.9e-18 66.7 0.0 3.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR68673.1 - 8.5e-07 30.1 0.0 1.5e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR68673.1 - 0.00083 18.7 0.1 0.0013 18.1 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EMR68673.1 - 0.0032 16.9 0.1 0.0053 16.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2688 PF10892.8 EMR68673.1 - 0.57 9.7 2.4 7.4 6.1 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) WXG100 PF06013.12 EMR68674.1 - 0.061 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF3391 PF11871.8 EMR68674.1 - 2.3 8.8 5.8 0.35 11.4 1.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Plus-3 PF03126.18 EMR68676.1 - 1.2e-31 109.4 0.1 8e-31 106.8 0.0 2.2 2 0 0 2 2 2 1 Plus-3 domain PLDc PF00614.22 EMR68677.1 - 2.8e-17 62.1 0.2 3.5e-07 30.1 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EMR68677.1 - 1.9e-13 50.5 0.0 1.6e-07 31.3 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain Fib_alpha PF08702.10 EMR68678.1 - 1.8e-05 24.9 15.9 0.00087 19.5 1.7 2.3 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 EMR68678.1 - 0.0016 18.0 6.7 0.0016 18.0 6.7 2.3 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 EMR68678.1 - 0.042 13.9 33.6 0.46 10.5 11.7 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 EMR68678.1 - 0.068 12.9 22.0 0.043 13.5 3.4 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 KASH_CCD PF14662.6 EMR68678.1 - 0.089 12.6 29.5 1.8 8.4 7.1 3.2 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH RasGAP_C PF03836.15 EMR68678.1 - 0.15 12.2 9.1 2 8.5 2.2 3.1 3 0 0 3 3 3 0 RasGAP C-terminus Phage_GP20 PF06810.11 EMR68678.1 - 0.24 11.2 13.6 2.6 7.9 2.1 3.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 FPP PF05911.11 EMR68678.1 - 0.25 9.5 26.0 0.085 11.0 13.6 1.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 EMR68678.1 - 0.45 10.6 13.2 0.31 11.1 1.6 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) IKKbetaNEMObind PF12179.8 EMR68678.1 - 0.46 10.6 2.8 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Tropomyosin PF00261.20 EMR68678.1 - 0.53 9.6 30.3 0.68 9.3 5.7 3.5 1 1 2 3 3 3 0 Tropomyosin VSG_B PF13206.6 EMR68678.1 - 0.76 9.0 7.0 1.2 8.3 7.0 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain DHR10 PF18595.1 EMR68678.1 - 0.77 9.8 37.7 18 5.4 16.6 3.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Fez1 PF06818.15 EMR68678.1 - 1.4 9.4 24.3 2.6 8.4 21.8 2.4 1 1 1 2 2 2 0 Fez1 Tropomyosin_1 PF12718.7 EMR68678.1 - 1.6 8.9 31.2 0.31 11.2 14.2 2.6 1 1 1 2 2 2 0 Tropomyosin like MAD PF05557.13 EMR68678.1 - 1.7 6.9 29.7 3.2 6.0 28.2 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF812 PF05667.11 EMR68678.1 - 2.1 7.2 26.6 14 4.4 26.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Leu_zip PF15294.6 EMR68678.1 - 3.9 6.9 22.4 51 3.2 21.9 2.2 1 1 0 1 1 1 0 Leucine zipper DUF4795 PF16043.5 EMR68678.1 - 4.7 6.8 21.3 10 5.6 21.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) CHD5 PF04420.14 EMR68678.1 - 5.1 6.9 9.2 2.4 8.0 6.0 2.1 1 1 0 2 2 2 0 CHD5-like protein DUF948 PF06103.11 EMR68678.1 - 5.1 7.4 6.5 7.2 6.9 0.2 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ERM PF00769.19 EMR68678.1 - 6.7 6.5 40.3 8.6 6.1 10.7 2.5 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.11 EMR68678.1 - 7.1 5.4 28.0 4.5 6.0 11.3 2.4 1 1 2 3 3 3 0 Spc7 kinetochore protein Lectin_N PF03954.14 EMR68678.1 - 8.3 6.2 7.5 1.5 8.5 1.7 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Uso1_p115_C PF04871.13 EMR68678.1 - 8.4 6.8 26.2 0.065 13.6 9.1 3.7 2 1 2 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 EMR68678.1 - 8.5 5.6 23.4 1.3 8.3 4.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.6 EMR68678.1 - 8.5 5.7 27.2 6.5 6.0 11.2 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding adh_short PF00106.25 EMR68679.1 - 6.5e-19 68.2 0.0 7.7e-17 61.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR68679.1 - 1.4e-10 41.4 0.1 2.5e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMR68679.1 - 4e-08 33.1 0.0 2.6e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 EMR68679.1 - 0.023 14.8 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EMR68679.1 - 0.065 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EMR68679.1 - 0.12 11.9 0.0 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 EMR68680.1 - 2.5e-50 171.4 4.3 3.3e-50 171.0 4.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR68680.1 - 3.1e-12 46.9 5.8 5e-11 43.0 1.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EMR68680.1 - 5.3e-05 23.7 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 EMR68680.1 - 0.00053 19.2 0.1 0.8 8.8 0.0 2.8 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Rieske PF00355.26 EMR68680.1 - 0.0012 18.8 0.0 0.0093 15.9 0.0 2.3 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.6 EMR68680.1 - 0.019 15.0 5.2 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EMR68680.1 - 0.034 14.6 0.4 0.42 11.1 0.0 2.3 1 1 1 2 2 2 0 Putative NAD(P)-binding Acetyltransf_10 PF13673.7 EMR68681.1 - 3.1e-08 33.6 0.0 5.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR68681.1 - 1.9e-06 28.1 0.0 6e-06 26.5 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR68681.1 - 3.2e-06 27.5 0.0 5.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR68681.1 - 0.05 13.7 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR68681.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Fungal_trans PF04082.18 EMR68682.1 - 1.8e-05 23.9 0.8 5.8e-05 22.3 0.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.31 EMR68683.1 - 2e-15 57.0 0.0 3.3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_20 PF00728.22 EMR68685.1 - 2.5e-25 89.6 2.2 3e-19 69.6 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 EMR68685.1 - 1.9e-10 41.6 0.0 7.4e-10 39.7 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 PAS_3 PF08447.12 EMR68685.1 - 0.048 14.0 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Glyco_hydro_88 PF07470.13 EMR68686.1 - 1.1e-84 284.5 3.7 1.4e-84 284.1 3.7 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EMR68686.1 - 0.0019 16.8 0.2 0.0026 16.3 0.2 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 OPT PF03169.15 EMR68687.1 - 1.6e-122 410.3 46.9 8.5e-47 160.1 11.0 4.0 2 1 1 3 3 3 3 OPT oligopeptide transporter protein SAPS PF04499.15 EMR68688.1 - 1.6e-189 630.8 0.0 1.6e-189 630.8 0.0 2.9 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein CLASP_N PF12348.8 EMR68690.1 - 0.0015 18.2 0.0 0.091 12.3 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal Adaptin_N PF01602.20 EMR68690.1 - 0.0036 15.9 0.4 2.4 6.6 0.2 2.5 2 1 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 EMR68690.1 - 0.0058 16.8 0.5 5.8 7.5 0.1 5.1 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EMR68690.1 - 0.021 14.9 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 EMR68690.1 - 0.04 14.0 1.1 0.082 13.0 0.0 2.1 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair GPS2_interact PF15784.5 EMR68690.1 - 0.04 14.3 2.9 0.16 12.4 2.4 2.4 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain MMS19_N PF14500.6 EMR68690.1 - 0.11 12.0 0.1 1.7 8.2 0.0 2.7 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II GHMP_kinases_C PF08544.13 EMR68690.1 - 0.12 12.7 0.3 11 6.5 0.0 3.6 3 0 0 3 3 3 0 GHMP kinases C terminal HALZ PF02183.18 EMR68690.1 - 0.17 12.1 10.9 0.095 12.9 3.1 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper Fez1 PF06818.15 EMR68690.1 - 1.6 9.1 8.2 4.4 7.7 8.2 1.6 1 0 0 1 1 1 0 Fez1 Jnk-SapK_ap_N PF09744.9 EMR68690.1 - 2.9 8.1 10.3 9.7 6.4 10.3 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 YabA PF06156.13 EMR68690.1 - 3.4 8.3 6.1 15 6.3 6.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Phage_Nu1 PF07471.12 EMR68690.1 - 4.1 7.2 6.4 3.9 7.2 1.5 2.5 1 1 1 2 2 2 0 Phage DNA packaging protein Nu1 ADIP PF11559.8 EMR68690.1 - 4.4 7.4 11.3 10 6.2 11.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 EMR68690.1 - 4.5 6.9 10.6 9 5.9 10.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Nic96 PF04097.14 EMR68691.1 - 3.1e-222 739.5 0.0 3.7e-222 739.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF3425 PF11905.8 EMR68692.1 - 1e-20 73.9 1.6 1.7e-20 73.2 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EMR68692.1 - 0.023 14.8 9.6 0.089 12.9 9.6 1.9 1 1 0 1 1 1 0 bZIP transcription factor DUF4164 PF13747.6 EMR68692.1 - 0.19 12.1 5.4 0.34 11.2 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) MerR-DNA-bind PF09278.11 EMR68692.1 - 1.5 9.4 5.9 1.3 9.6 3.7 2.1 1 1 1 2 2 2 0 MerR, DNA binding GATase_2 PF00310.21 EMR68693.1 - 4.4e-183 608.8 0.0 6.7e-183 608.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EMR68693.1 - 7.5e-152 505.7 0.0 1.1e-151 505.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EMR68693.1 - 3e-109 364.8 0.0 3e-107 358.3 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EMR68693.1 - 6.8e-87 290.0 2.6 1.1e-86 289.3 2.6 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EMR68693.1 - 1.4e-22 80.3 0.4 7.6e-22 77.9 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EMR68693.1 - 9.3e-22 76.9 0.1 1.7e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EMR68693.1 - 3.7e-09 36.7 0.0 1.3e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR68693.1 - 3.4e-08 33.5 0.4 0.00047 19.9 0.1 3.0 3 0 0 3 3 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR68693.1 - 3.4e-07 30.7 0.1 8.2e-05 23.1 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR68693.1 - 1.8e-06 27.6 0.0 3.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EMR68693.1 - 3.5e-05 22.7 1.3 4e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EMR68693.1 - 6.6e-05 22.3 0.2 0.044 13.0 0.0 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR68693.1 - 0.00041 19.8 0.1 0.00082 18.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR68693.1 - 0.0012 18.0 0.1 0.004 16.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 EMR68693.1 - 0.0026 16.2 0.2 0.91 7.9 0.0 3.0 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 EMR68693.1 - 0.0029 16.9 0.2 0.015 14.5 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EMR68693.1 - 0.0051 16.1 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EMR68693.1 - 0.0089 16.5 1.6 2.8 8.4 0.1 3.1 3 0 0 3 3 3 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 EMR68693.1 - 0.013 15.6 0.8 6.3 6.9 0.1 2.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMN_dh PF01070.18 EMR68693.1 - 0.017 14.1 0.5 0.12 11.3 0.6 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.23 EMR68693.1 - 0.03 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 EMR68693.1 - 0.13 11.6 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EMR68693.1 - 0.16 11.0 0.8 0.8 8.7 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A K_oxygenase PF13434.6 EMR68693.1 - 0.19 10.8 0.0 18 4.3 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Glyco_hydro_47 PF01532.20 EMR68694.1 - 6.8e-172 572.5 0.0 7.9e-172 572.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.32 EMR68695.1 - 9.2e-33 111.8 14.8 2e-09 37.9 0.4 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 EMR68695.1 - 8.4e-08 31.3 0.2 0.0098 14.6 0.0 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EMR68695.1 - 1.4e-07 31.7 0.0 0.00021 21.5 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EMR68695.1 - 0.0037 16.1 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 EMR68695.1 - 0.12 10.9 0.0 2.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain VTC PF09359.10 EMR68696.1 - 1.3e-86 290.4 0.5 2.4e-86 289.6 0.5 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EMR68696.1 - 8.4e-12 45.4 1.4 8.4e-12 45.4 1.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EMR68696.1 - 3.8e-10 40.3 20.8 5.3e-05 23.3 0.2 4.1 2 1 2 4 4 4 2 SPX domain Uds1 PF15456.6 EMR68696.1 - 0.43 10.8 5.7 5.5 7.2 2.1 2.9 2 0 0 2 2 2 0 Up-regulated During Septation ADH_N_2 PF16884.5 EMR68697.1 - 1.9e-18 66.3 0.0 4.2e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EMR68697.1 - 4.6e-18 65.5 0.0 6.5e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR68697.1 - 4e-05 24.7 0.0 7.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PGM_PMM_II PF02879.16 EMR68697.1 - 0.13 12.9 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MFS_1 PF07690.16 EMR68698.1 - 2.4e-31 109.0 26.2 3.1e-31 108.6 26.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Ycf70 PF17382.2 EMR68698.1 - 0.3 11.5 0.9 3.4 8.1 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized Ycf70-like AA_permease PF00324.21 EMR68699.1 - 7.2e-144 479.9 38.9 8.3e-144 479.7 38.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR68699.1 - 2e-37 129.0 43.2 2.6e-37 128.7 43.2 1.1 1 0 0 1 1 1 1 Amino acid permease CHAT PF12770.7 EMR68700.1 - 4.5e-33 114.9 0.0 5.5e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.17 EMR68700.1 - 0.018 14.1 0.0 0.046 12.9 0.0 1.6 1 1 0 1 1 1 0 Peptidase family C50 Peptidase_C25 PF01364.18 EMR68700.1 - 0.073 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 Apolipoprotein PF01442.18 EMR68700.1 - 0.084 12.7 0.6 0.15 12.0 0.6 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Peptidase_C14 PF00656.22 EMR68700.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Caspase domain Tektin PF03148.14 EMR68700.1 - 0.13 10.9 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Tektin family TolA_bind_tri PF16331.5 EMR68700.1 - 7.2 6.8 7.1 7 6.8 0.5 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation FGGY_C PF02782.16 EMR68702.1 - 2e-49 168.1 0.1 2.8e-49 167.6 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EMR68702.1 - 1.4e-22 80.4 0.4 5e-21 75.4 0.4 2.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 EMR68702.1 - 0.0071 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Glycos_transf_2 PF00535.26 EMR68703.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_hydro_12 PF01670.16 EMR68704.1 - 5.1e-14 52.8 1.7 6.8e-14 52.4 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 OST3_OST6 PF04756.13 EMR68705.1 - 0.24 10.7 1.9 0.3 10.4 1.9 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family CENP-O PF09496.10 EMR68707.1 - 2.8e-72 243.1 0.1 5e-72 242.3 0.0 1.4 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DUF3700 PF12481.8 EMR68707.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein zf-C2H2_jaz PF12171.8 EMR68708.1 - 3.4e-07 30.4 1.8 6e-07 29.6 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMR68708.1 - 0.00039 20.7 0.5 0.00066 20.0 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EMR68708.1 - 0.049 14.1 0.7 0.083 13.4 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR68708.1 - 0.061 14.2 0.3 0.12 13.3 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EMR68708.1 - 0.07 13.5 0.5 0.11 12.8 0.5 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 EMR68708.1 - 0.13 12.4 1.3 0.22 11.6 1.3 1.4 1 0 0 1 1 1 0 DBF zinc finger A_deaminase PF00962.22 EMR68709.1 - 3.2e-21 76.0 0.0 9e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 Adenosine/AMP deaminase OTT_1508_deam PF14441.6 EMR68710.1 - 2.8e-19 68.9 1.7 6.5e-19 67.7 1.7 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Z1 PF10593.9 EMR68710.1 - 0.18 11.2 1.6 0.19 11.2 0.2 1.6 2 0 0 2 2 2 0 Z1 domain Acatn PF13000.7 EMR68712.1 - 2.3e-167 557.8 20.4 1.2e-81 274.9 10.4 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF1691 PF07950.11 EMR68713.1 - 9.7e-38 129.2 9.0 1.4e-29 102.9 4.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) DUF4405 PF14358.6 EMR68713.1 - 0.019 15.5 1.5 4.6 7.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) SCPU PF05229.15 EMR68714.1 - 0.019 15.4 0.1 0.024 15.0 0.1 1.2 1 0 0 1 1 1 0 Spore Coat Protein U domain DJ-1_PfpI PF01965.24 EMR68715.1 - 1.2e-14 54.5 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family EF-hand_2 PF09068.11 EMR68715.1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 EF hand Sugar_tr PF00083.24 EMR68716.1 - 5.8e-62 210.0 15.1 9.8e-59 199.4 11.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR68716.1 - 3.9e-18 65.5 19.2 5.4e-18 65.0 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR68716.1 - 0.00054 19.4 0.6 0.00054 19.4 0.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB EXS PF03124.14 EMR68716.1 - 0.051 12.9 2.1 1.2 8.4 0.3 2.1 2 0 0 2 2 2 0 EXS family DUF981 PF06168.11 EMR68716.1 - 1.4 8.8 10.3 0.087 12.7 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF981) p450 PF00067.22 EMR68717.1 - 9.6e-60 202.6 0.0 1e-59 202.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EMR68718.1 - 0.0059 16.5 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR68718.1 - 0.18 11.8 0.5 0.36 10.8 0.1 1.7 2 0 0 2 2 2 0 F-box domain TPP_enzyme_N PF02776.18 EMR68719.1 - 3e-55 186.5 0.0 3.8e-54 182.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMR68719.1 - 6e-49 165.7 0.0 2.5e-48 163.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMR68719.1 - 3.4e-40 136.9 0.4 6.4e-40 136.1 0.4 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain SDH_alpha PF03313.15 EMR68720.1 - 5.2e-88 295.1 14.0 1.7e-80 270.4 12.0 2.2 1 1 1 2 2 2 2 Serine dehydratase alpha chain SDH_beta PF03315.15 EMR68720.1 - 1.6e-53 181.2 0.1 3.4e-53 180.2 0.1 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain Fungal_trans_2 PF11951.8 EMR68721.1 - 0.0025 16.7 0.0 0.0035 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EMR68723.1 - 8.5e-30 103.8 0.3 1.2e-29 103.3 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM178 PF14816.6 EMR68723.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Abhydrolase_1 PF00561.20 EMR68724.1 - 5.6e-19 68.8 0.0 8e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Aldo_ket_red PF00248.21 EMR68725.1 - 2.5e-41 141.8 0.0 2.9e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UNC-93 PF05978.16 EMR68726.1 - 8e-12 45.1 8.5 8e-12 45.1 8.5 2.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EMR68726.1 - 1.5e-07 30.7 30.3 1.5e-07 30.7 30.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 EMR68727.1 - 8.2e-32 110.5 0.1 9.4e-32 110.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EMR68728.1 - 3.9e-31 108.2 26.0 5.6e-31 107.7 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PDR_assoc PF08370.11 EMR68728.1 - 0.042 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Plant PDR ABC transporter associated SieB PF14163.6 EMR68728.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B Trp_oprn_chp PF09534.10 EMR68728.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.6 2 2 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EutQ PF06249.12 EMR68729.1 - 7.8e-10 38.7 0.0 9.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EMR68729.1 - 2.3e-08 33.6 0.0 3.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EMR68729.1 - 5.7e-05 22.7 0.1 7.4e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EMR68729.1 - 0.086 12.4 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 EMR68729.1 - 0.16 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin PhyH PF05721.13 EMR68730.1 - 9.1e-13 48.9 0.0 1.7e-12 48.1 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_3 PF01494.19 EMR68732.1 - 2.2e-68 231.0 0.0 3.6e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMR68732.1 - 9.8e-56 188.3 0.0 1.9e-55 187.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Glyco_transf_28 PF03033.20 EMR68733.1 - 4.4e-24 85.1 0.0 1e-23 83.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 EMR68733.1 - 0.024 14.9 1.0 2.7 8.4 0.0 3.6 4 0 0 4 4 4 0 Autophagy-related protein C terminal domain Peptidase_M24 PF00557.24 EMR68734.1 - 2.7e-10 40.3 0.0 4.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Sugar_tr PF00083.24 EMR68735.1 - 3.6e-102 342.5 23.4 4.4e-102 342.3 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR68735.1 - 1.6e-23 83.3 33.0 2.1e-21 76.3 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 EMR68735.1 - 0.028 15.0 1.7 0.13 12.8 1.7 2.2 1 0 0 1 1 1 0 Phage holin family 2 CAP PF00188.26 EMR68736.1 - 0.00068 20.5 0.0 0.0051 17.7 0.0 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family PepSY_2 PF13670.6 EMR68736.1 - 0.97 9.5 2.6 1.7 8.7 2.6 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain GST_N PF02798.20 EMR68737.1 - 6.9e-16 58.4 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR68737.1 - 4.6e-14 52.6 0.0 9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMR68737.1 - 8.3e-12 45.2 0.0 2.1e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR68737.1 - 1e-11 44.9 0.0 2.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR68737.1 - 4e-09 36.5 0.0 8.3e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR68737.1 - 5.6e-09 35.9 0.0 9.8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 EMR68738.1 - 2.8e-15 56.1 48.2 7.7e-11 41.5 23.5 3.0 2 2 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR68738.1 - 7e-08 31.3 20.0 9.1e-08 31.0 20.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DAGK_prokar PF01219.19 EMR68738.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.8 3 0 0 3 3 3 0 Prokaryotic diacylglycerol kinase DUF4407 PF14362.6 EMR68738.1 - 6.2 6.1 5.5 5.9 6.1 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GMC_oxred_N PF00732.19 EMR68739.1 - 3.8e-38 131.5 1.0 1.2e-29 103.7 0.1 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR68739.1 - 6.3e-33 114.3 0.0 1.7e-32 112.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR68739.1 - 5.7e-07 29.0 2.9 0.003 16.7 0.5 2.2 1 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EMR68739.1 - 1.8e-06 27.4 0.8 0.00011 21.6 0.5 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR68739.1 - 5.9e-06 26.4 0.2 1.8e-05 24.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR68739.1 - 2.3e-05 24.2 4.0 0.00051 19.7 0.8 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR68739.1 - 3.2e-05 23.3 0.3 8.4e-05 21.9 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR68739.1 - 4.8e-05 22.6 0.7 0.00015 20.9 0.7 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EMR68739.1 - 0.00064 18.5 0.4 0.011 14.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EMR68739.1 - 0.0057 15.9 0.1 0.013 14.8 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EMR68739.1 - 0.015 15.2 0.6 0.074 13.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMR68739.1 - 0.017 15.6 0.1 0.081 13.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMR68739.1 - 0.02 15.2 0.3 0.17 12.2 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 EMR68739.1 - 0.029 13.5 0.1 0.4 9.8 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EMR68739.1 - 0.11 11.7 0.1 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EMR68740.1 - 4.6e-30 105.4 0.7 5.5e-30 105.1 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR68740.1 - 0.00017 22.1 1.8 0.0018 18.8 1.7 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR68740.1 - 0.0054 16.0 0.1 0.015 14.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR68740.1 - 0.089 11.8 0.1 0.17 10.9 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EMR68740.1 - 0.18 11.0 1.5 0.24 10.6 0.1 1.8 2 0 0 2 2 2 0 Thi4 family DUF4804 PF16062.5 EMR68741.1 - 1e-92 311.3 0.0 4.2e-58 197.3 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4804) KNOX1 PF03790.13 EMR68741.1 - 0.088 12.5 0.0 1.7 8.4 0.0 2.7 3 0 0 3 3 3 0 KNOX1 domain AltA1 PF16541.5 EMR68742.1 - 1.2e-28 100.2 1.6 1.6e-28 99.7 1.6 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 C6 PF01681.17 EMR68742.1 - 1.3 9.6 5.8 17 6.0 5.9 2.8 1 1 1 2 2 2 0 C6 domain Sugar_tr PF00083.24 EMR68743.1 - 6.3e-19 68.2 3.4 6.8e-19 68.0 3.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Bax1-I PF01027.20 EMR68743.1 - 0.019 14.8 3.5 0.022 14.6 3.5 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Rab5ip PF07019.12 EMR68743.1 - 0.15 12.7 2.9 0.26 11.9 2.9 1.6 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) BTP PF05232.12 EMR68743.1 - 1.8 8.7 6.2 13 5.9 0.6 2.4 2 0 0 2 2 2 0 Chlorhexidine efflux transporter Aminotran_4 PF01063.19 EMR68744.1 - 1.7e-42 145.8 0.0 2e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Rick_17kDa_Anti PF05433.15 EMR68745.1 - 4.4e-06 26.5 12.5 4.4e-06 26.5 12.5 1.6 2 0 0 2 2 2 1 Glycine zipper 2TM domain Nucleo_P87 PF07267.11 EMR68745.1 - 0.052 12.4 2.3 0.07 12.0 2.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AAA PF00004.29 EMR68746.1 - 1.1e-17 64.7 0.0 3.3e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) U1snRNP70_N PF12220.8 EMR68746.1 - 0.0037 17.9 2.9 0.0091 16.6 2.9 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SART-1 PF03343.13 EMR68746.1 - 0.0047 15.6 13.5 0.0064 15.1 13.5 1.1 1 0 0 1 1 1 1 SART-1 family AAA_11 PF13086.6 EMR68746.1 - 0.0083 15.9 3.7 3.4 7.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain SR-25 PF10500.9 EMR68746.1 - 0.019 14.6 10.3 0.031 13.9 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YL1 PF05764.13 EMR68746.1 - 0.044 13.9 14.7 0.069 13.3 14.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein AAA_16 PF13191.6 EMR68746.1 - 0.07 13.5 0.5 5.1 7.4 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain Tim54 PF11711.8 EMR68746.1 - 0.09 11.6 7.5 0.15 10.8 7.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 EMR68746.1 - 0.099 11.8 1.5 0.14 11.4 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 EMR68746.1 - 0.1 10.9 8.5 0.14 10.4 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.6 EMR68746.1 - 0.13 12.5 0.0 1.1 9.5 0.0 2.5 2 1 1 3 3 3 0 AAA domain DUF778 PF05608.12 EMR68746.1 - 0.17 12.2 1.1 0.94 9.8 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF778) PI3K_1B_p101 PF10486.9 EMR68746.1 - 0.31 8.8 4.4 0.45 8.2 4.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MCM_bind PF09739.9 EMR68746.1 - 1.9 6.8 7.2 2.7 6.3 7.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor YqfQ PF14181.6 EMR68746.1 - 3.1 8.0 10.2 5.5 7.2 10.2 1.4 1 0 0 1 1 1 0 YqfQ-like protein RNA_pol_Rpc4 PF05132.14 EMR68746.1 - 5 7.5 7.9 8.7 6.8 7.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Rtf2 PF04641.12 EMR68746.1 - 8.3 5.7 14.5 13 5.0 14.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger MCM2_N PF12619.8 EMR68747.1 - 0.022 15.0 1.1 0.025 14.9 0.2 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 FlaG PF03646.15 EMR68747.1 - 0.06 13.5 0.3 0.26 11.5 0.1 1.9 2 0 0 2 2 2 0 FlaG protein RNA12 PF10443.9 EMR68747.1 - 0.13 10.9 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 RNA12 protein Cutinase PF01083.22 EMR68748.1 - 2.3e-34 118.9 0.7 2.8e-34 118.6 0.7 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EMR68748.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain NAD_binding_4 PF07993.12 EMR68749.1 - 1.1e-32 113.3 0.0 1.5e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EMR68749.1 - 6e-16 58.6 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR68749.1 - 9.7e-08 32.3 0.0 2.3e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EMR68749.1 - 1.2e-06 28.2 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EMR68749.1 - 0.0021 18.0 0.1 0.018 15.0 0.1 2.4 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EMR68749.1 - 0.0025 16.9 0.0 0.0054 15.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMR68749.1 - 0.015 14.4 0.0 0.35 9.9 0.0 2.6 2 1 0 2 2 2 0 RmlD substrate binding domain Milton PF12448.8 EMR68749.1 - 0.081 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Kinesin associated protein DUF3612 PF12268.8 EMR68749.1 - 0.16 12.1 0.3 14 5.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3612) Pyridoxal_deC PF00282.19 EMR68753.1 - 4.2e-09 35.6 0.0 0.00053 18.8 0.0 2.7 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_3_C PF01915.22 EMR68754.1 - 6.8e-51 173.1 0.2 1.1e-50 172.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR68754.1 - 3.6e-37 128.4 0.0 5.8e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR68754.1 - 7.9e-24 83.6 0.0 1.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.24 EMR68755.1 - 1.7e-119 399.7 24.5 1.9e-119 399.5 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR68755.1 - 4.5e-19 68.6 45.6 2e-14 53.3 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 EMR68757.1 - 1.3e-12 47.8 0.0 2.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR68757.1 - 0.13 12.1 0.5 0.82 9.6 0.3 2.2 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Aldo_ket_red PF00248.21 EMR68758.1 - 4.7e-62 209.8 0.0 5.8e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Metal_resist PF13801.6 EMR68758.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Collagen PF01391.18 EMR68759.1 - 6.3e-09 35.5 10.7 1.1e-08 34.7 10.7 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) THOC2_N PF16134.5 EMR68761.1 - 6.8e-218 725.3 0.0 9.8e-218 724.8 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EMR68761.1 - 4.7e-90 301.8 0.4 6.9e-90 301.3 0.4 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EMR68761.1 - 6.2e-25 87.1 0.0 2.1e-24 85.3 0.0 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit AUX_IAA PF02309.16 EMR68761.1 - 0.13 12.1 0.1 0.81 9.5 0.1 2.1 2 0 0 2 2 2 0 AUX/IAA family HET PF06985.11 EMR68762.1 - 7.5e-10 39.3 4.1 9.9e-07 29.2 0.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Abhydrolase_1 PF00561.20 EMR68763.1 - 2.7e-07 30.5 0.0 3.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EMR68763.1 - 0.035 14.2 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein ABC_tran PF00005.27 EMR68764.1 - 5.4e-50 169.5 0.0 1.4e-29 103.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR68764.1 - 3.2e-37 128.7 2.0 2.7e-24 86.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EMR68764.1 - 4.9e-10 39.2 0.8 0.00038 20.0 0.0 4.0 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EMR68764.1 - 3.6e-06 26.2 0.0 0.056 12.5 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 EMR68764.1 - 5.5e-05 23.6 1.0 0.016 15.6 0.2 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EMR68764.1 - 0.00015 22.4 0.8 0.56 10.7 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EMR68764.1 - 0.00016 22.0 0.0 0.15 12.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMR68764.1 - 0.00035 20.2 1.9 0.2 11.4 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EMR68764.1 - 0.0025 17.1 0.3 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.23 EMR68764.1 - 0.003 17.6 0.5 0.25 11.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EMR68764.1 - 0.0041 16.9 0.4 4.5 7.0 0.1 2.8 2 1 0 2 2 2 2 AAA domain CbiA PF01656.23 EMR68764.1 - 0.0078 16.3 0.8 4.3 7.4 0.0 2.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 EMR68764.1 - 0.0078 16.1 0.7 2.2 8.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EMR68764.1 - 0.014 14.9 1.1 0.43 10.1 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EMR68764.1 - 0.03 14.1 2.3 2.7 7.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EMR68764.1 - 0.031 14.0 1.8 0.75 9.5 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein ResIII PF04851.15 EMR68764.1 - 0.036 14.1 0.1 4.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 EMR68764.1 - 0.039 13.7 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMR68764.1 - 0.17 11.4 0.3 6.9 6.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 EMR68764.1 - 0.19 11.8 5.4 2.7 8.0 0.3 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 EMR68764.1 - 0.29 11.1 0.5 7 6.7 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EMR68764.1 - 0.34 10.8 6.1 1.1 9.1 0.1 3.2 4 0 0 4 4 4 0 NACHT domain AAA_5 PF07728.14 EMR68764.1 - 0.39 10.7 3.5 8.6 6.4 0.2 3.4 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 EMR68764.1 - 0.89 8.4 2.4 8.8 5.1 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain VSP PF03302.13 EMR68765.1 - 3.2e-05 23.0 0.2 4.1e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EMR68765.1 - 0.0012 19.0 0.6 0.0019 18.3 0.6 1.3 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 EMR68765.1 - 0.013 16.1 1.1 0.029 14.9 1.1 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Rax2 PF12768.7 EMR68765.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.20 EMR68765.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain E1-E2_ATPase PF00122.20 EMR68767.1 - 4.9e-34 117.4 12.2 1.8e-29 102.6 0.6 3.7 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMR68767.1 - 3.6e-27 95.2 3.4 3.6e-27 95.2 3.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EMR68767.1 - 3.5e-21 75.1 0.0 6.5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMR68767.1 - 2e-18 67.5 0.1 1.9e-13 51.2 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMR68767.1 - 1.6e-17 62.9 0.1 5.2e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMR68767.1 - 1.4e-07 31.5 0.4 9.8e-06 25.5 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3915 PF13054.6 EMR68767.1 - 0.19 11.7 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Pkinase PF00069.25 EMR68768.1 - 0.00042 19.8 0.0 0.00043 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain adh_short PF00106.25 EMR68769.1 - 0.0027 17.2 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR68769.1 - 0.023 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 EMR68769.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_18 PF00704.28 EMR68770.1 - 4e-27 95.8 0.3 7e-27 95.0 0.3 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Cupin_2 PF07883.11 EMR68771.1 - 4.2e-07 29.6 0.1 7e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 EMR68771.1 - 0.04 13.8 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase SnoaL PF07366.12 EMR68772.1 - 0.06 13.2 0.2 7.3 6.4 0.1 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase FAD_binding_4 PF01565.23 EMR68773.1 - 1.1e-18 67.3 1.2 1.9e-18 66.5 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR68773.1 - 2.9e-10 40.1 0.8 6.9e-10 38.9 0.8 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EMR68773.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Cupin_2 PF07883.11 EMR68775.1 - 4.7e-20 71.1 0.7 4e-18 64.9 0.4 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EMR68775.1 - 0.00046 20.1 0.3 0.001 19.0 0.3 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 EMR68775.1 - 0.0036 16.9 0.1 0.098 12.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) TauD PF02668.16 EMR68777.1 - 0.0001 22.2 0.0 0.00013 21.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 EMR68778.1 - 6.1e-50 170.4 19.4 1e-49 169.7 19.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR68778.1 - 9.3e-22 77.4 28.0 9.3e-22 77.4 28.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly_transf_sug PF04488.15 EMR68779.1 - 3.5e-10 40.4 0.1 7.3e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EMR68779.1 - 3e-09 36.7 0.1 4e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Inhibitor_I71 PF12628.7 EMR68781.1 - 1.6 8.5 11.9 1.2 8.9 0.2 2.2 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Secretin_N_2 PF07655.13 EMR68781.1 - 8.2 7.0 11.4 15 6.2 11.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain TTL PF03133.15 EMR68782.1 - 9.6e-35 120.1 0.0 8.5e-34 117.0 0.0 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EMR68782.1 - 0.00018 20.9 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp PNMA PF14893.6 EMR68782.1 - 0.018 14.4 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 PNMA Dala_Dala_lig_C PF07478.13 EMR68782.1 - 0.03 13.9 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Glyco_hydro_2_C PF02836.17 EMR68783.1 - 4.3e-103 344.6 0.1 5.7e-103 344.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EMR68783.1 - 5.9e-61 206.2 0.0 2.3e-59 200.9 0.0 3.0 2 1 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EMR68783.1 - 1.1e-43 149.0 0.1 2.1e-43 148.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EMR68783.1 - 3.6e-18 65.8 0.0 1.6e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EMR68783.1 - 1.8e-13 51.1 0.0 3.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EMR68783.1 - 0.00042 20.9 0.0 0.0013 19.3 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain CBM60 PF16841.5 EMR68783.1 - 0.087 13.3 0.2 0.33 11.4 0.1 2.1 2 0 0 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding MFS_1 PF07690.16 EMR68784.1 - 8.2e-28 97.3 91.4 2e-23 82.9 54.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AIM24 PF01987.17 EMR68785.1 - 3e-36 125.1 0.0 3.9e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PIP5K PF01504.18 EMR68786.1 - 6.7e-43 146.9 0.0 1.2e-42 146.1 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Kinesin PF00225.23 EMR68788.1 - 1.2e-79 267.6 0.1 1.2e-79 267.6 0.1 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EMR68788.1 - 2.1e-21 76.4 0.0 4.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 EMR68788.1 - 0.0069 16.6 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EMR68788.1 - 0.036 14.7 0.3 0.21 12.2 0.1 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix domain TFIIA PF03153.13 EMR68788.1 - 0.18 11.8 20.9 0.013 15.5 16.0 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.6 EMR68788.1 - 3.7 8.0 8.0 0.45 10.9 3.3 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MerR-DNA-bind PF09278.11 EMR68788.1 - 4.9 7.8 8.8 6 7.5 3.3 3.3 1 1 2 3 3 3 0 MerR, DNA binding PQ-loop PF04193.14 EMR68789.1 - 1.1e-39 134.0 8.7 5.4e-20 70.9 0.6 2.6 2 0 0 2 2 2 2 PQ loop repeat Caskin-Pro-rich PF16907.5 EMR68789.1 - 0.041 14.4 0.1 0.041 14.4 0.1 2.2 2 0 0 2 2 2 0 Proline rich region of Caskin proteins MtN3_slv PF03083.16 EMR68789.1 - 0.56 10.3 3.9 0.52 10.4 0.3 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange BTB PF00651.31 EMR68790.1 - 1.2e-11 44.8 0.0 7.4e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain NUDIX PF00293.28 EMR68791.1 - 3.1e-16 59.6 0.0 5.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EMR68791.1 - 2.3e-11 44.3 0.1 4.8e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EMR68791.1 - 2.7e-05 23.7 1.6 5.1e-05 22.8 1.6 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain LEA_1 PF03760.15 EMR68792.1 - 0.031 14.9 0.2 0.031 14.9 0.2 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 PRA-PH PF01503.17 EMR68792.1 - 0.067 13.6 1.0 0.11 13.0 0.1 1.8 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase dCMP_cyt_deam_1 PF00383.23 EMR68793.1 - 2.3e-10 40.2 1.4 3.7e-09 36.4 1.4 2.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMR68793.1 - 3e-05 23.8 0.4 8e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 MafB19-like deaminase Bd3614-deam PF14439.6 EMR68793.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase Arm PF00514.23 EMR68797.1 - 1.5e-12 47.1 0.2 1.4e-05 25.0 0.0 4.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EMR68797.1 - 0.0025 17.9 2.3 4.5 7.8 0.1 4.5 5 0 0 5 5 5 2 HEAT repeat SPX PF03105.19 EMR68797.1 - 0.58 10.0 3.5 0.91 9.4 3.3 1.5 1 1 0 1 1 1 0 SPX domain Ank_5 PF13857.6 EMR68798.1 - 1.3e-14 54.1 0.0 1.7e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR68798.1 - 3.7e-11 43.5 0.0 7.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EMR68798.1 - 4e-11 42.9 0.0 1.1e-06 28.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.24 EMR68798.1 - 4e-11 42.8 1.6 1.9e-10 40.6 0.8 2.4 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.6 EMR68798.1 - 5.7e-11 42.7 0.2 1.5e-07 31.8 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR68798.1 - 9.1e-09 34.9 0.0 0.00012 22.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Cauli_VI PF01693.16 EMR68799.1 - 7.8e-38 128.5 6.5 3e-20 72.2 0.8 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 EMR68799.1 - 3.4e-36 124.6 0.3 5.5e-36 123.9 0.3 1.3 1 0 0 1 1 1 1 RNase H DUF4611 PF15387.6 EMR68799.1 - 0.15 12.2 7.7 0.37 11.0 7.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 EMR68799.1 - 0.18 10.0 1.6 0.22 9.8 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 EMR68799.1 - 0.54 10.7 4.2 1 9.8 4.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 6PF2K PF01591.18 EMR68800.1 - 2.2e-60 203.7 0.0 9.5e-45 152.6 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EMR68800.1 - 6.5e-29 101.0 0.2 4.2e-24 85.3 0.0 2.6 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Sigma70_r4_2 PF08281.12 EMR68800.1 - 0.14 11.8 0.1 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 FAD_binding_3 PF01494.19 EMR68801.1 - 5.8e-26 91.6 0.0 1.5e-25 90.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR68801.1 - 0.00083 19.5 0.1 0.0019 18.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR68801.1 - 0.011 14.8 0.5 0.046 12.8 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EMR68801.1 - 0.066 12.4 0.5 0.43 9.7 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Phage_TAC_4 PF08748.11 EMR68801.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.8 1 1 0 1 1 1 0 Phage tail assembly chaperone Trp_halogenase PF04820.14 EMR68801.1 - 0.2 10.4 0.9 2.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 EMR68802.1 - 7.3e-09 35.7 0.1 1.7e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMR68802.1 - 2.3e-06 27.2 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EMR68802.1 - 0.0027 17.0 0.1 0.0077 15.5 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR68802.1 - 0.005 16.1 0.1 0.0086 15.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR68802.1 - 0.005 16.1 0.2 0.018 14.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMR68802.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 EMR68802.1 - 0.015 14.6 0.1 0.041 13.1 0.1 1.7 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EMR68802.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 EMR68802.1 - 0.029 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 EMR68802.1 - 0.033 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR68802.1 - 0.043 13.8 0.1 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EMR68802.1 - 0.055 12.5 0.1 0.085 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EMR68802.1 - 0.079 12.0 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Cyclin PF08613.11 EMR68803.1 - 1.9e-23 83.6 0.1 3e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EMR68803.1 - 0.01 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain CHZ PF09649.10 EMR68804.1 - 5.7e-19 67.3 1.5 5.7e-19 67.3 1.5 2.6 3 0 0 3 3 3 1 Histone chaperone domain CHZ GP24_25 PF17388.2 EMR68804.1 - 0.063 13.3 0.7 0.063 13.3 0.7 2.0 1 1 1 2 2 2 0 Tail assembly gene products 24 & 25 HATPase_c PF02518.26 EMR68807.1 - 1.6e-30 105.9 0.0 3.5e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMR68807.1 - 3.9e-21 75.3 0.2 9.7e-21 74.0 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EMR68807.1 - 6.5e-18 64.5 0.3 2.6e-17 62.6 0.3 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EMR68807.1 - 1.1e-11 45.2 0.0 2.6e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EMR68807.1 - 5.8e-09 36.7 0.0 1.3e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 EMR68807.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 EMR68807.1 - 0.0041 17.5 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 GAF domain BOFC_N PF08977.10 EMR68807.1 - 0.13 12.2 0.6 0.33 11.0 0.6 1.6 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal Prenylcys_lyase PF07156.14 EMR68808.1 - 1.5e-90 304.0 0.0 1.8e-90 303.7 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EMR68808.1 - 1.3e-13 51.0 0.3 5.4e-13 49.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMR68808.1 - 5.7e-12 45.7 0.0 8.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EMR68808.1 - 3.1e-07 30.3 0.2 1.3e-05 25.0 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR68808.1 - 9.8e-05 22.4 0.2 0.00047 20.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMR68808.1 - 0.00062 19.1 0.0 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR68808.1 - 0.0014 17.9 0.1 0.048 12.9 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EMR68808.1 - 0.085 11.9 0.2 0.15 11.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 EMR68808.1 - 0.11 11.3 0.2 0.2 10.4 0.1 1.5 2 0 0 2 2 2 0 MCRA family Trp_halogenase PF04820.14 EMR68808.1 - 0.13 11.1 0.5 0.23 10.2 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 EMR68808.1 - 0.16 12.6 0.1 1.7 9.3 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMR68808.1 - 0.88 8.6 3.3 0.26 10.3 0.3 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Cpn60_TCP1 PF00118.24 EMR68809.1 - 2.6e-161 537.6 0.3 3e-161 537.4 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family B12-binding_2 PF02607.17 EMR68810.1 - 0.0018 18.7 0.0 0.021 15.3 0.0 2.4 3 0 0 3 3 3 1 B12 binding domain GSu_C4xC__C2xCH PF09698.10 EMR68810.1 - 0.015 16.0 1.9 0.035 14.9 1.9 1.7 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) COesterase PF00135.28 EMR68811.1 - 2.6e-79 267.4 0.0 3.5e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR68811.1 - 7.9e-08 32.4 0.3 0.00014 21.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Neocarzinostat PF00960.18 EMR68811.1 - 0.045 13.7 0.2 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Neocarzinostatin family SOBP PF15279.6 EMR68811.1 - 0.11 13.0 0.5 0.19 12.3 0.5 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein eIF-3_zeta PF05091.12 EMR68812.1 - 6.6e-206 685.3 0.0 7.7e-206 685.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 EMR68812.1 - 0.074 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF569) PAS PF00989.25 EMR68813.1 - 1.5e-05 24.9 0.1 9.9e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 PAS fold PAS_9 PF13426.7 EMR68813.1 - 0.00028 21.1 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EMR68813.1 - 0.012 15.9 0.1 0.025 14.9 0.0 1.5 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.10 EMR68813.1 - 0.093 13.0 0.0 0.45 10.8 0.0 1.9 1 1 1 2 2 2 0 PAS fold Serpentine_r_xa PF03383.15 EMR68814.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Ribul_P_3_epim PF00834.19 EMR68815.1 - 2.6e-59 199.9 0.0 1.1e-58 197.9 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 EMR68815.1 - 0.085 12.4 0.4 0.25 10.9 0.3 1.8 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DNA_pol_phi PF04931.13 EMR68816.1 - 0.023 12.8 17.0 0.034 12.3 17.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 EMR68816.1 - 0.39 10.6 11.6 0.96 9.3 11.6 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 EMR68816.1 - 1.3 7.5 12.9 1.8 7.0 12.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CCDC106 PF15794.5 EMR68816.1 - 2.4 7.8 15.3 5.4 6.7 5.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 BUD22 PF09073.10 EMR68816.1 - 4.7 6.4 36.1 10 5.3 35.9 1.5 1 1 0 1 1 1 0 BUD22 DUF913 PF06025.12 EMR68816.1 - 8.3 5.3 6.3 0.99 8.3 2.2 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Ofd1_CTDD PF10637.9 EMR68817.1 - 3.7e-93 311.6 0.0 5e-89 298.0 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EMR68817.1 - 4.1e-25 88.3 0.0 4.8e-24 84.8 0.0 2.5 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EMR68817.1 - 6.6e-13 49.4 0.0 1.4e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SLC12 PF03522.15 EMR68817.1 - 0.75 8.7 7.1 2.1 7.3 7.1 1.7 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 EMR68817.1 - 5.3 6.2 7.3 12 5.0 7.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter NAD_binding_4 PF07993.12 EMR68819.1 - 4.3e-42 144.0 0.1 1.7e-40 138.8 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein PP-binding PF00550.25 EMR68819.1 - 9.8e-10 38.7 0.0 2.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EMR68819.1 - 1.5e-06 27.8 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR68819.1 - 0.00019 20.5 0.0 0.0004 19.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMR68819.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMR68819.1 - 0.028 14.3 0.3 0.32 10.9 0.0 2.6 1 1 1 2 2 2 0 NAD(P)H-binding KR PF08659.10 EMR68819.1 - 0.064 13.2 0.0 0.26 11.2 0.0 2.0 1 1 0 1 1 1 0 KR domain TRAPP PF04051.16 EMR68821.1 - 1.5e-11 44.2 0.1 1.8e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.6 EMR68821.1 - 0.093 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) PBP1_TM PF14812.6 EMR68822.1 - 0.015 15.7 7.1 0.02 15.3 3.4 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3611 PF12263.8 EMR68822.1 - 0.044 13.7 0.2 0.068 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Arteri_Gl PF00951.18 EMR68822.1 - 0.077 12.8 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein WD40 PF00400.32 EMR68823.1 - 1.3e-27 95.5 4.9 0.0009 20.0 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR68823.1 - 9.3e-12 45.1 0.1 0.00018 21.7 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EMR68823.1 - 0.022 13.5 0.8 3.2 6.4 0.1 2.8 1 1 1 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 EMR68823.1 - 0.075 12.3 0.1 3.9 6.7 0.0 2.9 1 1 2 3 3 3 0 WD40-like domain Pkinase PF00069.25 EMR68824.1 - 9.6e-76 254.6 0.0 1.4e-75 254.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR68824.1 - 1.1e-38 133.1 0.0 5.2e-38 130.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR68824.1 - 1.3e-11 44.3 0.0 7e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMR68824.1 - 7.4e-07 28.3 0.0 9.9e-07 27.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FHA PF00498.26 EMR68824.1 - 2.3e-05 24.6 0.0 6.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 EMR68824.1 - 0.0028 17.0 0.1 0.0064 15.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EMR68824.1 - 0.016 14.9 0.2 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 EMR68824.1 - 0.031 13.3 0.1 0.062 12.3 0.1 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 EMR68824.1 - 0.044 12.7 0.1 0.069 12.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EMR68824.1 - 0.079 12.9 0.1 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2961 PF11175.8 EMR68824.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) ArfGap PF01412.18 EMR68825.1 - 1.2e-33 115.7 0.0 3.3e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EMR68825.1 - 2.2e-22 79.9 11.3 3.5e-22 79.3 11.3 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EMR68825.1 - 5.8e-06 26.8 0.3 7.2e-05 23.3 0.1 2.4 2 0 0 2 2 2 1 PH domain EMP24_GP25L PF01105.24 EMR68825.1 - 0.53 10.2 2.8 4.8 7.1 2.4 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD HAMP PF00672.25 EMR68826.1 - 2.8e-39 133.3 14.0 7.7e-08 32.6 0.1 7.3 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.26 EMR68826.1 - 1.1e-30 106.4 0.1 3.7e-30 104.7 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMR68826.1 - 5.7e-27 94.1 0.2 3.6e-26 91.5 0.3 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EMR68826.1 - 1.7e-17 63.2 2.3 8.5e-17 61.0 0.5 3.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 EMR68826.1 - 1.3e-07 31.9 9.1 1.1 9.7 0.0 7.5 5 2 2 8 8 7 1 Syntaxin-like protein DUF948 PF06103.11 EMR68826.1 - 3.2e-05 24.1 38.3 1.1 9.5 1.5 9.0 4 3 2 6 6 6 3 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 EMR68826.1 - 0.0022 18.6 7.3 4.7 7.9 0.1 5.1 3 1 1 4 4 4 2 Bacterial protein of unknown function (DUF883) DUF4795 PF16043.5 EMR68826.1 - 0.0058 16.3 23.5 0.016 14.8 0.2 5.0 3 3 1 4 4 4 2 Domain of unknown function (DUF4795) GLE1 PF07817.13 EMR68826.1 - 0.034 13.4 5.1 17 4.5 0.1 3.9 2 1 2 4 4 4 0 GLE1-like protein IL32 PF15225.6 EMR68826.1 - 0.038 14.3 0.2 5.7 7.4 0.0 4.0 3 2 0 3 3 3 0 Interleukin 32 DUF4279 PF14106.6 EMR68826.1 - 0.051 13.8 0.0 20 5.4 0.0 4.3 5 0 0 5 5 4 0 Domain of unknown function (DUF4279) GhoS PF11080.8 EMR68826.1 - 0.17 11.9 7.2 1.7 8.7 0.1 4.6 5 0 0 5 5 4 0 Endoribonuclease GhoS Fib_alpha PF08702.10 EMR68826.1 - 0.29 11.3 31.5 0.63 10.2 2.1 6.3 6 0 0 6 6 6 0 Fibrinogen alpha/beta chain family WXG100 PF06013.12 EMR68826.1 - 0.88 9.8 26.7 3.2 8.0 0.3 7.2 5 2 2 7 7 7 0 Proteins of 100 residues with WXG PilJ PF13675.6 EMR68826.1 - 0.97 9.5 11.7 5.3 7.1 0.2 5.6 5 1 1 7 7 7 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3829 PF12889.7 EMR68826.1 - 1.1 8.7 13.8 6 6.3 0.1 5.1 5 2 1 6 6 6 0 Protein of unknown function (DUF3829) CENP-F_leu_zip PF10473.9 EMR68826.1 - 1.6 8.8 25.8 4.9 7.2 0.1 7.5 7 2 0 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rotamase PF00639.21 EMR68826.1 - 2.8 9.0 7.4 41 5.2 0.1 4.9 2 1 2 5 5 5 0 PPIC-type PPIASE domain MukF_M PF17192.4 EMR68826.1 - 5.7 6.7 21.4 8.1 6.2 0.2 5.3 3 3 2 5 5 5 0 MukF middle domain NUDIX PF00293.28 EMR68827.1 - 3.1e-09 36.9 0.2 1e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain Membr_traf_MHD PF10540.9 EMR68828.1 - 9.7e-20 71.2 0.6 1.2e-15 58.0 0.5 3.5 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EMR68828.1 - 1.2e-17 64.1 0.0 2.9e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EMR68828.1 - 2.6e-06 26.3 1.7 3.3e-06 26.0 0.5 1.8 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) Rep_N PF08724.10 EMR68828.1 - 0.032 14.0 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 Rep protein catalytic domain like PLDc PF00614.22 EMR68829.1 - 6.4e-16 57.8 1.3 2.5e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EMR68829.1 - 6.8e-15 55.1 0.1 8.4e-07 28.9 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain DUF2992 PF11208.8 EMR68829.1 - 0.0062 16.8 2.3 0.079 13.2 2.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2992) gpUL132 PF11359.8 EMR68829.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DEAD PF00270.29 EMR68830.1 - 2.9e-42 144.4 0.2 4.3e-42 143.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR68830.1 - 2.7e-19 69.6 0.0 1.1e-18 67.6 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMR68830.1 - 8.9e-15 54.7 0.0 1.9e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EMR68830.1 - 2e-05 24.7 0.0 3.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMR68830.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AflR PF08493.10 EMR68830.1 - 7.4 6.0 12.2 2.5 7.5 6.0 2.3 2 0 0 2 2 2 0 Aflatoxin regulatory protein UPF0086 PF01868.16 EMR68832.1 - 4e-32 110.0 0.4 6.8e-32 109.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 adh_short PF00106.25 EMR68833.1 - 4.7e-17 62.1 0.0 1.6e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR68833.1 - 1.2e-07 31.8 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR68833.1 - 0.00088 18.8 0.0 0.0028 17.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 EMR68833.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EMR68833.1 - 0.22 10.6 0.0 0.41 9.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_2 PF07719.17 EMR68834.1 - 4.3e-06 26.4 3.4 0.0099 15.9 0.6 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMR68834.1 - 4.2e-05 23.2 4.5 0.17 11.7 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMR68834.1 - 0.00022 21.4 1.6 0.001 19.3 1.3 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMR68834.1 - 0.00062 19.4 2.0 0.0017 18.0 0.6 2.2 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 EMR68834.1 - 0.00071 19.4 2.4 1.2 9.4 0.1 3.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMR68834.1 - 0.008 16.7 0.6 0.028 14.9 0.6 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR68834.1 - 0.078 13.2 5.2 0.2 11.9 5.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EMR68834.1 - 0.087 13.7 1.2 1.9 9.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Caldesmon PF02029.15 EMR68834.1 - 0.3 9.8 24.0 0.44 9.3 24.0 1.1 1 0 0 1 1 1 0 Caldesmon DUF4407 PF14362.6 EMR68834.1 - 5.2 6.3 11.2 7.4 5.8 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAD_2 PF13419.6 EMR68835.1 - 9.9e-12 45.3 0.0 2.4e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR68835.1 - 1.1e-07 32.4 0.0 1.3e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR68835.1 - 0.00035 20.6 0.1 0.00071 19.6 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EMR68835.1 - 0.0094 16.0 0.1 0.056 13.5 0.0 2.4 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EMR68835.1 - 0.068 13.6 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Snf7 PF03357.21 EMR68836.1 - 3.4e-17 62.6 11.9 5.3e-17 61.9 11.9 1.3 1 0 0 1 1 1 1 Snf7 HAUS-augmin3 PF14932.6 EMR68836.1 - 0.078 12.6 16.1 0.019 14.5 8.0 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GIT1_C PF12205.8 EMR68836.1 - 0.12 12.4 3.3 0.48 10.6 3.3 1.9 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Ldi PF18566.1 EMR68836.1 - 0.21 11.0 0.2 0.36 10.3 0.2 1.3 1 0 0 1 1 1 0 Linalool dehydratase/isomerase CorA PF01544.18 EMR68836.1 - 0.34 10.2 6.9 0.062 12.6 1.4 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 EMR68836.1 - 0.85 9.9 8.2 8.4 6.7 0.6 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Not3 PF04065.15 EMR68836.1 - 0.85 9.0 4.9 0.12 11.8 0.7 1.6 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF2203 PF09969.9 EMR68836.1 - 2.7 8.7 14.3 0.17 12.6 0.5 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 EMR68836.1 - 6.1 6.9 6.5 0.96 9.5 1.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TauD PF02668.16 EMR68837.1 - 1.9e-63 214.8 1.5 2.3e-63 214.5 1.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans_2 PF11951.8 EMR68838.1 - 2.3e-09 36.6 1.2 3.3e-09 36.0 1.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain PPR_2 PF13041.6 EMR68839.1 - 3.3e-49 164.9 13.1 1.6e-08 34.6 0.0 13.3 10 4 5 15 15 15 9 PPR repeat family PPR_3 PF13812.6 EMR68839.1 - 1.2e-34 118.2 0.1 0.0025 17.9 0.0 11.0 7 3 3 11 11 11 8 Pentatricopeptide repeat domain PPR PF01535.20 EMR68839.1 - 3.8e-29 98.9 23.0 0.00012 22.1 0.1 13.9 16 0 0 16 16 16 6 PPR repeat PPR_1 PF12854.7 EMR68839.1 - 1.5e-28 98.2 1.6 1.4e-07 31.1 0.0 11.5 12 0 0 12 12 12 5 PPR repeat PPR_long PF17177.4 EMR68839.1 - 2.6e-22 79.2 13.7 3.1e-08 33.2 0.1 7.4 4 3 3 7 7 7 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EMR68839.1 - 7.6e-06 26.3 0.0 0.007 16.8 0.0 4.4 5 1 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 EMR68839.1 - 0.00039 20.3 1.5 0.015 15.1 0.2 4.1 4 1 1 5 5 5 1 Mitochondrial ATPase expression TPR_1 PF00515.28 EMR68839.1 - 0.11 12.3 1.7 8.7 6.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMR68839.1 - 0.49 10.7 4.7 15 6.1 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMR68839.1 - 0.76 10.0 2.5 36 4.8 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 EMR68840.1 - 1.8e-13 50.1 9.3 3.5e-13 49.2 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMR68840.1 - 6.7e-10 38.7 9.5 1.3e-09 37.8 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR68840.1 - 1.8e-08 34.1 7.0 2.9e-08 33.4 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR68840.1 - 1.8e-08 34.3 6.9 3.6e-08 33.3 6.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger SAP PF02037.27 EMR68840.1 - 5.4e-08 32.4 0.1 1e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain zf-RING_5 PF14634.6 EMR68840.1 - 1.9e-07 30.9 9.0 4.1e-07 29.9 9.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EMR68840.1 - 3e-07 30.7 8.8 5.9e-07 29.7 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 EMR68840.1 - 1.2e-06 28.3 2.4 2.2e-06 27.5 2.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EMR68840.1 - 1.6e-06 28.3 3.6 4.2e-06 27.0 3.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EMR68840.1 - 3.4e-06 27.1 9.0 9.3e-06 25.7 9.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EMR68840.1 - 6.5e-06 25.9 7.4 1.3e-05 25.0 7.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 U-box PF04564.15 EMR68840.1 - 0.00033 20.8 0.5 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.6 EMR68840.1 - 0.0008 19.1 2.0 0.0008 19.1 2.0 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EMR68840.1 - 0.0013 18.9 4.4 0.0024 18.0 4.4 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 Mob_synth_C PF06463.13 EMR68840.1 - 0.0096 15.9 2.6 0.0096 15.9 2.6 2.0 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C zf-ANAPC11 PF12861.7 EMR68840.1 - 0.038 14.0 0.8 0.038 14.0 0.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EMR68840.1 - 0.11 12.3 3.4 0.22 11.3 3.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 EMR68840.1 - 0.27 10.9 8.8 0.16 11.6 6.0 2.0 2 0 0 2 2 2 0 P-11 zinc finger Bravo_FIGEY PF13882.6 EMR68840.1 - 1.3 10.4 9.9 0.13 13.7 3.2 2.4 2 0 0 2 2 2 0 Bravo-like intracellular region BTB PF00651.31 EMR68841.1 - 0.0031 17.7 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain LOB PF03195.14 EMR68841.1 - 0.05 14.2 0.0 0.096 13.3 0.0 1.4 1 0 0 1 1 1 0 Lateral organ boundaries (LOB) domain Amidase PF01425.21 EMR68842.1 - 3e-97 326.5 0.0 1.8e-69 234.9 0.2 2.2 2 0 0 2 2 2 2 Amidase Exop_C PF18559.1 EMR68844.1 - 0.0029 17.5 0.0 0.0055 16.6 0.0 1.4 1 1 0 1 1 1 1 Galactose-binding domain-like CHB_HEX_C_1 PF13290.6 EMR68844.1 - 0.061 13.3 0.1 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain NmrA PF05368.13 EMR68845.1 - 5.6e-42 143.9 0.0 7.2e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR68845.1 - 1.8e-22 80.1 0.0 2.6e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR68845.1 - 4e-08 33.0 0.1 1.7e-07 31.0 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMR68845.1 - 0.0044 16.5 0.4 0.0072 15.8 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 EMR68845.1 - 0.013 16.0 0.3 0.048 14.3 0.3 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 EMR68845.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PALP PF00291.25 EMR68845.1 - 0.051 13.0 0.3 0.1 12.0 0.3 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 EMR68845.1 - 0.066 13.5 0.2 0.14 12.5 0.2 1.6 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EMR68845.1 - 0.11 12.4 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SNARE PF05739.19 EMR68846.1 - 6.5e-05 22.8 0.3 0.00076 19.4 0.0 2.3 2 1 0 2 2 2 1 SNARE domain DprA_WH PF17782.1 EMR68846.1 - 0.0092 16.1 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 1 DprA winged helix domain DUF4446 PF14584.6 EMR68846.1 - 0.018 15.0 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CENP-H PF05837.12 EMR68846.1 - 0.052 14.0 0.4 0.062 13.7 0.4 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4726 PF15855.5 EMR68846.1 - 0.15 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) MFS_1 PF07690.16 EMR68847.1 - 3.2e-51 174.3 25.0 3.2e-51 174.3 25.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily FA_desaturase PF00487.24 EMR68847.1 - 7.7 6.3 14.0 4.6 7.0 1.9 3.1 2 1 1 3 3 3 0 Fatty acid desaturase Methyltransf_11 PF08241.12 EMR68848.1 - 5.1e-05 23.8 0.0 7.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR68848.1 - 0.00049 19.9 0.0 0.00054 19.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CDC27 PF09507.10 EMR68849.1 - 1.5e-67 228.9 45.6 1.2e-47 163.3 39.8 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 Fe_dep_repress PF01325.19 EMR68849.1 - 0.0058 16.8 0.1 1.6 9.0 0.0 2.9 3 0 0 3 3 3 2 Iron dependent repressor, N-terminal DNA binding domain CENP-B_dimeris PF09026.10 EMR68850.1 - 3.5 8.1 9.3 39 4.7 9.9 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glyco_hydro_92 PF07971.12 EMR68851.1 - 2.4e-109 366.3 0.0 1.5e-93 314.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMR68851.1 - 2.1e-40 139.1 0.0 4.1e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain NMD3 PF04981.13 EMR68852.1 - 1.1e-59 201.9 3.1 1.6e-59 201.4 3.1 1.2 1 0 0 1 1 1 1 NMD3 family NAD2 PF18782.1 EMR68852.1 - 0.04 14.0 0.4 0.066 13.3 0.4 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 DUF5321 PF17254.2 EMR68852.1 - 0.098 12.1 2.6 0.18 11.2 2.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5321) C1_1 PF00130.22 EMR68852.1 - 5.3 7.0 8.5 0.45 10.5 2.0 2.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DPBB_1 PF03330.18 EMR68853.1 - 0.00011 22.4 3.1 0.0014 18.9 0.0 2.3 2 1 1 3 3 3 2 Lytic transglycolase Barwin PF00967.17 EMR68853.1 - 0.0025 17.7 0.5 0.0029 17.5 0.5 1.3 1 1 0 1 1 1 1 Barwin family CDC48_N PF02359.18 EMR68853.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Acyltransferase PF01553.21 EMR68854.1 - 4.3e-05 23.2 0.0 8.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase RAP PF08373.10 EMR68854.1 - 0.037 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 RAP domain DHHC PF01529.20 EMR68854.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Aminotran_1_2 PF00155.21 EMR68855.1 - 1.4e-85 287.7 0.0 1.6e-85 287.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.24 EMR68856.1 - 1.6e-71 241.6 23.2 1.6e-64 218.4 19.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR68856.1 - 2e-27 96.1 49.5 4.9e-27 94.8 48.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR68856.1 - 7.7e-05 21.7 4.5 7.7e-05 21.7 4.5 2.4 2 1 0 2 2 2 1 MFS_1 like family OATP PF03137.20 EMR68856.1 - 0.00074 17.9 12.9 0.026 12.8 7.3 3.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family TMEM40 PF15817.5 EMR68856.1 - 6.1 6.6 7.1 1 9.2 0.2 2.3 2 0 0 2 2 2 0 Transmembrane protein 40 family GLTP PF08718.11 EMR68857.1 - 1.8e-47 161.3 0.0 3.7e-47 160.3 0.0 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) adh_short PF00106.25 EMR68858.1 - 9.4e-19 67.6 0.0 2.3e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68858.1 - 5.9e-09 35.8 0.0 8.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68858.1 - 7.6e-06 26.0 0.0 1.1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR68858.1 - 0.23 10.8 0.1 0.31 10.4 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HAD_2 PF13419.6 EMR68859.1 - 2.6e-13 50.4 0.0 5.6e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR68859.1 - 3.3e-06 27.5 0.0 0.0029 17.9 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR68859.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like TRAPPC-Trs85 PF12739.7 EMR68860.1 - 8.7e-59 199.5 1.0 1.1e-58 199.2 1.0 1.0 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Isochorismatase PF00857.20 EMR68861.1 - 2.8e-18 66.7 0.0 2.5e-17 63.6 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family DUF1996 PF09362.10 EMR68862.1 - 3.7e-59 200.6 1.3 1e-34 120.6 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) 2OG-FeII_Oxy PF03171.20 EMR68863.1 - 1.2e-17 64.2 0.0 2.7e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMR68863.1 - 1.7e-12 48.1 0.0 3.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal NSP10 PF09401.10 EMR68864.1 - 0.23 11.5 1.2 0.5 10.4 1.2 1.5 1 0 0 1 1 1 0 RNA synthesis protein NSP10 SnoaL PF07366.12 EMR68865.1 - 4.6e-29 100.8 0.4 3.9e-25 88.1 0.1 3.3 2 1 1 3 3 3 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EMR68865.1 - 2.7e-10 40.8 0.2 4.4e-09 36.9 0.0 2.7 2 1 1 3 3 3 1 SnoaL-like domain COesterase PF00135.28 EMR68866.1 - 1.2e-08 34.3 0.0 1.3e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family LpxK PF02606.14 EMR68867.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Ank_2 PF12796.7 EMR68868.1 - 2e-24 86.0 0.4 5.9e-10 39.6 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR68868.1 - 6.2e-21 74.5 0.1 0.00018 22.0 0.1 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EMR68868.1 - 2.2e-18 65.8 0.9 0.01 16.2 0.0 6.2 6 0 0 6 6 5 4 Ankyrin repeat Ank_5 PF13857.6 EMR68868.1 - 7.5e-13 48.4 0.2 0.029 14.7 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR68868.1 - 6.8e-12 44.5 0.5 0.0077 16.7 0.0 6.0 5 0 0 5 5 5 2 Ankyrin repeat Helo_like_N PF17111.5 EMR68868.1 - 5.9e-08 32.3 1.8 1.5e-07 31.0 1.8 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 EMR68868.1 - 0.00052 20.2 2.2 0.00069 19.8 0.6 2.1 2 0 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_12 PF13424.6 EMR68868.1 - 0.00058 20.1 0.2 0.0025 18.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF1664 PF07889.12 EMR68868.1 - 0.0018 18.3 0.5 0.0077 16.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) TPR_2 PF07719.17 EMR68868.1 - 0.0021 18.1 1.0 0.013 15.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TMCO5 PF14992.6 EMR68868.1 - 0.012 15.2 2.8 0.023 14.3 2.8 1.3 1 0 0 1 1 1 0 TMCO5 family TPR_10 PF13374.6 EMR68868.1 - 0.016 15.0 0.1 0.058 13.3 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMR68868.1 - 0.017 15.3 0.0 0.065 13.5 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMR68868.1 - 0.027 15.0 0.3 0.38 11.3 0.2 2.8 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF1722 PF08349.11 EMR68868.1 - 0.038 14.3 0.6 0.11 12.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) WEMBL PF05701.11 EMR68868.1 - 0.065 11.9 0.8 0.12 11.1 0.8 1.4 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TPR_1 PF00515.28 EMR68868.1 - 0.075 12.9 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR68868.1 - 0.089 13.7 0.2 2.4 9.2 0.0 3.5 4 1 1 5 5 1 0 Tetratricopeptide repeat MukF_M PF17192.4 EMR68868.1 - 0.15 11.8 2.1 0.34 10.6 2.1 1.6 1 0 0 1 1 1 0 MukF middle domain Snapin_Pallidin PF14712.6 EMR68868.1 - 0.15 12.5 4.6 5.9 7.4 0.4 3.0 1 1 0 2 2 2 0 Snapin/Pallidin TPR_17 PF13431.6 EMR68868.1 - 0.17 12.3 0.1 0.72 10.4 0.0 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat ROS_MUCR PF05443.11 EMR68868.1 - 0.19 11.8 0.4 2.1 8.4 0.4 2.5 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein FapA PF03961.13 EMR68868.1 - 0.2 10.2 1.6 0.27 9.8 0.6 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Serglycin PF04360.12 EMR68868.1 - 0.24 11.3 2.8 0.64 10.0 2.8 1.7 1 0 0 1 1 1 0 Serglycin Ran-binding PF05508.11 EMR68868.1 - 0.35 9.8 3.8 0.78 8.7 2.6 2.0 1 1 1 2 2 2 0 RanGTP-binding protein Exonuc_VII_L PF02601.15 EMR68868.1 - 0.41 10.2 2.5 0.9 9.0 2.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rx_N PF18052.1 EMR68868.1 - 0.7 10.2 3.2 73 3.7 0.0 4.0 4 0 0 4 4 4 0 Rx N-terminal domain UPF0029 PF01205.19 EMR68869.1 - 2.2e-20 73.0 0.0 4.6e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Not1 PF04054.15 EMR68870.1 - 4.1e-95 318.8 0.0 2.9e-94 316.0 0.0 2.3 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EMR68870.1 - 2.6e-90 301.8 1.0 5.3e-90 300.7 1.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EMR68870.1 - 2.1e-49 167.2 3.9 2.1e-49 167.2 3.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EMR68870.1 - 2.4e-41 141.0 0.0 5.9e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EMR68870.1 - 3.6e-40 137.5 0.7 2.1e-39 135.0 0.2 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat TPR_20 PF14561.6 EMR68870.1 - 0.089 13.1 0.1 31 5.0 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EMR68871.1 - 6.1e-18 65.2 0.0 1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR68871.1 - 1.9e-06 28.6 0.0 0.00072 20.3 0.0 3.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR68871.1 - 0.00031 21.4 0.1 0.17 12.6 0.0 3.3 1 1 2 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR68871.1 - 0.0034 18.0 0.0 2.2 9.0 0.0 3.2 1 1 2 3 3 3 1 Methyltransferase domain Sugar_tr PF00083.24 EMR68872.1 - 1.7e-27 96.4 4.5 2.9e-16 59.4 0.1 3.4 4 0 0 4 4 4 3 Sugar (and other) transporter NIF PF03031.18 EMR68873.1 - 1.2e-22 80.4 0.0 1.5e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Jnk-SapK_ap_N PF09744.9 EMR68874.1 - 0.013 15.8 8.9 0.013 15.8 8.9 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Herpes_BLRF2 PF05812.12 EMR68874.1 - 0.025 14.7 2.6 0.07 13.3 2.6 1.9 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein V_ATPase_I PF01496.19 EMR68874.1 - 0.053 11.5 1.4 0.068 11.1 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4349 PF14257.6 EMR68874.1 - 0.12 11.8 3.8 0.44 9.9 3.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) FRG PF08867.11 EMR68874.1 - 0.15 13.0 0.9 1.4 9.9 0.4 2.5 2 1 0 2 2 2 0 FRG domain TSC22 PF01166.18 EMR68874.1 - 0.42 11.0 5.7 7.2 7.0 0.6 3.5 2 1 2 4 4 4 0 TSC-22/dip/bun family DUF4164 PF13747.6 EMR68874.1 - 0.8 10.0 5.5 0.9 9.9 1.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 EMR68874.1 - 2 8.5 16.1 0.12 12.5 8.3 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Glyco_hydro_43 PF04616.14 EMR68875.1 - 5.6e-55 186.7 3.5 7e-55 186.4 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PSGP PF07276.11 EMR68875.1 - 0.0016 18.7 0.6 0.0042 17.3 0.6 1.7 1 0 0 1 1 1 1 Apopolysialoglycoprotein (PSGP) HSP70 PF00012.20 EMR68876.1 - 2.3e-06 26.1 0.1 2.7e-05 22.6 0.0 2.3 3 0 0 3 3 3 2 Hsp70 protein ABC1 PF03109.16 EMR68877.1 - 5.1e-33 113.7 0.0 8.6e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EMR68877.1 - 0.017 14.5 0.0 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Rit1_C PF17184.4 EMR68878.1 - 5.9e-107 357.2 0.0 7.7e-107 356.8 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EMR68878.1 - 5.2e-26 91.1 0.0 1.1e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Spc7 PF08317.11 EMR68879.1 - 3.1e-06 26.3 8.1 5.5e-06 25.5 8.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein TMPIT PF07851.13 EMR68879.1 - 0.0074 15.6 3.9 0.011 15.0 3.9 1.2 1 0 0 1 1 1 1 TMPIT-like protein HAUS6_N PF14661.6 EMR68879.1 - 0.017 14.7 4.4 0.029 13.9 4.4 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4201 PF13870.6 EMR68879.1 - 0.054 13.2 7.9 0.29 10.9 4.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) FliJ PF02050.16 EMR68879.1 - 0.1 12.8 6.8 0.17 12.1 6.2 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein YlqD PF11068.8 EMR68879.1 - 0.17 12.3 5.5 0.4 11.1 5.2 1.7 1 1 0 1 1 1 0 YlqD protein FUSC PF04632.12 EMR68879.1 - 0.24 9.9 0.9 0.36 9.3 0.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Snapin_Pallidin PF14712.6 EMR68879.1 - 0.26 11.8 3.6 1 9.8 2.8 2.5 2 1 0 2 2 2 0 Snapin/Pallidin Not3 PF04065.15 EMR68879.1 - 0.41 10.0 8.0 0.28 10.6 5.4 2.0 2 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component BRE1 PF08647.11 EMR68879.1 - 0.79 9.8 7.3 0.64 10.1 0.7 2.6 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 EMR68879.1 - 1.4 9.0 5.4 6.8 6.7 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EMR68879.1 - 1.7 9.1 8.8 1.2 9.6 6.1 1.9 1 1 1 2 2 2 0 Fez1 TSNAXIP1_N PF15739.5 EMR68879.1 - 1.8 9.0 6.3 13 6.2 1.4 2.6 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus CENP-H PF05837.12 EMR68879.1 - 2.4 8.6 8.8 3.8 7.9 6.9 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FlxA PF14282.6 EMR68879.1 - 2.9 7.9 9.9 1.2 9.2 4.8 2.5 1 1 1 2 2 2 0 FlxA-like protein SPATA1_C PF15743.5 EMR68879.1 - 3 7.9 7.4 0.48 10.5 3.5 1.7 2 0 0 2 2 1 0 Spermatogenesis-associated C-terminus Fib_alpha PF08702.10 EMR68879.1 - 9 6.5 8.2 1.7 8.9 3.0 2.2 2 1 0 2 2 1 0 Fibrinogen alpha/beta chain family RRP36 PF06102.12 EMR68880.1 - 1e-54 185.0 20.3 1e-54 185.0 20.3 1.9 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 DNA_pol_phi PF04931.13 EMR68880.1 - 0.0011 17.2 21.8 0.0011 17.2 21.8 1.4 2 0 0 2 2 2 1 DNA polymerase phi KOW PF00467.29 EMR68884.1 - 6.4e-05 22.7 0.6 0.00015 21.6 0.6 1.7 1 0 0 1 1 1 1 KOW motif NINJA_B PF16136.5 EMR68884.1 - 1.5 9.2 8.9 1.1 9.7 2.5 2.4 2 0 0 2 2 2 0 Putative nuclear localisation signal Ras PF00071.22 EMR68886.1 - 2e-45 154.3 0.0 2.4e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR68886.1 - 3.3e-14 53.1 0.0 5.4e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Skp1 PF01466.19 EMR68886.1 - 0.2 11.8 1.0 1.2 9.3 0.1 2.6 3 0 0 3 3 3 0 Skp1 family, dimerisation domain DJ-1_PfpI PF01965.24 EMR68887.1 - 5.2e-10 39.4 0.0 6.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Hce2 PF14856.6 EMR68888.1 - 3.2e-19 69.1 1.0 5.3e-19 68.4 1.0 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DEAD PF00270.29 EMR68890.1 - 3.7e-49 166.8 0.0 2.4e-48 164.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR68890.1 - 1.4e-35 122.0 0.0 1.6e-32 112.1 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain MDM1 PF15501.6 EMR68890.1 - 0.011 14.9 23.9 0.015 14.4 23.9 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 CMS1 PF14617.6 EMR68890.1 - 0.019 14.3 0.0 0.019 14.3 0.0 4.2 2 1 2 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit SRP1_TIP1 PF00660.17 EMR68890.1 - 0.066 13.3 0.1 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 Seripauperin and TIP1 family SOBP PF15279.6 EMR68890.1 - 0.26 11.9 14.2 0.4 11.2 14.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Sporozoite_P67 PF05642.11 EMR68890.1 - 1.1 7.3 23.5 1.6 6.7 23.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SRP-alpha_N PF04086.13 EMR68890.1 - 1.7 8.5 33.7 2.7 7.9 33.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AF-4 PF05110.13 EMR68890.1 - 5.3 5.0 34.4 7.1 4.6 34.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NifU_N PF01592.16 EMR68891.1 - 2.3e-53 179.8 0.0 3.1e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain bMG5 PF17972.1 EMR68891.1 - 0.038 14.4 0.0 0.063 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain TSCPD PF12637.7 EMR68891.1 - 0.055 13.7 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain GTP_EFTU PF00009.27 EMR68892.1 - 3.3e-50 170.3 0.0 5.5e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EMR68892.1 - 9.1e-42 141.6 5.7 1.5e-41 140.9 5.7 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EMR68892.1 - 1.3e-18 66.7 0.0 2.6e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMR68892.1 - 1.3e-05 25.4 0.2 3.7e-05 24.0 0.1 1.9 2 0 0 2 2 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMR68892.1 - 2.9e-05 24.1 0.1 7.5e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EMR68892.1 - 0.00018 21.1 0.0 0.0007 19.2 0.0 1.9 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 EMR68892.1 - 0.00041 20.4 0.0 0.0012 18.9 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EMR68892.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EMR68892.1 - 0.04 13.4 0.0 0.12 11.8 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EMR68892.1 - 0.11 12.8 0.0 0.81 9.9 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 EMR68892.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Snurportin1 PF11538.8 EMR68892.1 - 0.23 11.7 2.6 0.44 10.8 2.6 1.4 1 0 0 1 1 1 0 Snurportin1 Dynamin_N PF00350.23 EMR68893.1 - 8.6e-13 48.7 0.0 4.1e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EMR68893.1 - 1.6e-06 28.1 0.0 3.8e-05 23.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR68893.1 - 0.00015 21.7 0.1 0.00055 19.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase IIGP PF05049.13 EMR68893.1 - 0.00021 20.5 0.0 0.00073 18.7 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EMR68893.1 - 0.00031 21.3 0.0 0.002 18.6 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EMR68893.1 - 0.011 16.1 0.1 0.042 14.2 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EMR68893.1 - 0.05 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EMR68893.1 - 0.084 12.1 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Septin TsaE PF02367.17 EMR68893.1 - 0.09 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AIG1 PF04548.16 EMR68893.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.7 1 1 0 1 1 1 0 AIG1 family Levi_coat PF01819.17 EMR68893.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Levivirus coat protein DUF5071 PF16804.5 EMR68893.1 - 0.13 12.5 5.2 1.2 9.5 0.1 3.8 2 1 1 4 4 4 0 Domain of unknown function (DUF5071) UCH PF00443.29 EMR68894.1 - 3.4e-34 118.5 0.0 5.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EMR68894.1 - 7.2e-24 83.3 0.1 3.6e-13 49.1 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 EMR68894.1 - 4.6e-22 77.5 2.1 2.6e-21 75.1 0.2 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 EMR68894.1 - 2.3e-21 75.9 14.1 4.2e-19 68.6 1.6 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EMR68894.1 - 1.1e-14 54.8 0.0 3.4e-13 49.9 0.0 3.0 2 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Rft-1 PF04506.13 EMR68895.1 - 1.8e-141 472.4 0.3 2e-141 472.2 0.3 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 EMR68895.1 - 4.3e-05 22.9 3.6 0.069 12.4 0.1 3.3 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 EMR68895.1 - 0.00016 21.1 1.6 0.00016 21.1 1.6 3.5 3 2 0 3 3 3 1 Polysaccharide biosynthesis protein HORMA PF02301.18 EMR68896.1 - 9.8e-33 113.5 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EMR68896.1 - 0.00032 20.7 0.2 0.0018 18.2 0.2 2.2 1 1 1 2 2 2 1 Autophagy-related protein 101 DUF2660 PF10859.8 EMR68896.1 - 0.021 15.2 0.1 0.052 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) bacHORMA_2 PF18173.1 EMR68896.1 - 0.034 14.0 0.1 0.092 12.6 0.1 1.7 1 1 0 1 1 1 0 Bacterial HORMA domain 2 Stirrup PF09061.6 EMR68896.1 - 0.037 14.2 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 Stirrup Anp1 PF03452.14 EMR68897.1 - 3.2e-110 367.7 0.1 6.6e-110 366.7 0.0 1.5 2 0 0 2 2 2 1 Anp1 Casc1_N PF15927.5 EMR68897.1 - 0.31 10.7 9.7 0.59 9.8 9.7 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF4337 PF14235.6 EMR68897.1 - 7.2 6.7 8.4 12 6.0 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FAD_binding_4 PF01565.23 EMR68898.1 - 2.3e-10 40.4 0.3 3.9e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EMR68898.1 - 2.4e-09 37.4 2.6 2.4e-09 37.4 2.6 2.1 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase Sec7 PF01369.20 EMR68900.1 - 9.3e-66 221.0 0.5 1.7e-65 220.2 0.5 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EMR68900.1 - 1.4e-17 64.1 0.0 1.6e-15 57.4 0.0 3.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EMR68900.1 - 0.0027 17.4 1.5 0.0056 16.4 0.4 2.1 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Glyco_hydro_61 PF03443.14 EMR68901.1 - 0.00035 20.6 0.0 0.00075 19.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Serglycin PF04360.12 EMR68901.1 - 0.017 15.1 13.9 0.071 13.1 1.9 2.3 2 0 0 2 2 2 0 Serglycin adh_short_C2 PF13561.6 EMR68902.1 - 1.8e-35 122.6 0.2 4.3e-22 78.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR68902.1 - 2.6e-32 111.9 1.0 1.2e-31 109.7 1.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR68902.1 - 5.5e-07 29.7 0.1 9.2e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR68902.1 - 5.7e-05 22.7 0.1 0.003 17.0 0.3 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR68902.1 - 0.003 17.5 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EMR68902.1 - 0.0038 16.3 0.3 0.0053 15.8 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EMR68902.1 - 0.029 14.6 0.4 0.046 14.0 0.4 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EMR68902.1 - 0.032 13.6 0.1 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EMR68902.1 - 0.033 14.4 0.5 0.054 13.8 0.5 1.3 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EMR68902.1 - 0.11 12.3 1.0 0.19 11.6 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1980 PF09323.10 EMR68903.1 - 0.029 14.3 1.1 0.062 13.2 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Nop14 PF04147.12 EMR68903.1 - 1.3 7.1 7.3 1.9 6.6 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family CCDC53 PF10152.9 EMR68903.1 - 5.4 7.4 9.3 2.6 8.4 3.3 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex GDA1_CD39 PF01150.17 EMR68904.1 - 1e-107 360.4 0.0 1.4e-107 360.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family p450 PF00067.22 EMR68905.1 - 1.1e-48 166.1 0.0 1.7e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 tRNA_anti_2 PF13742.6 EMR68905.1 - 0.19 11.9 0.0 0.75 10.0 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Peptidase_M19 PF01244.21 EMR68906.1 - 4.6e-93 311.9 0.0 5.4e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DDE_Tnp_1_assoc PF13808.6 EMR68906.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-associated tRNA-synt_His PF13393.6 EMR68907.1 - 7.9e-38 130.5 0.0 1.9e-37 129.2 0.0 1.6 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EMR68907.1 - 1.1e-08 35.1 0.1 6.6e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.20 EMR68907.1 - 0.008 15.3 0.0 0.14 11.3 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Peptidase_M91 PF14891.6 EMR68908.1 - 0.15 12.4 0.0 5.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Effector protein Glyco_hydro_42 PF02449.15 EMR68909.1 - 2.5e-105 352.9 2.7 3.1e-105 352.6 2.7 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.10 EMR68909.1 - 1.8e-24 86.4 0.0 2.7e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_14 PF01373.17 EMR68909.1 - 0.00048 19.2 0.1 0.00074 18.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_42C PF08533.10 EMR68909.1 - 0.0017 18.1 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain RHS PF03527.14 EMR68909.1 - 0.0031 17.2 0.1 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 RHS protein Cellulase PF00150.18 EMR68909.1 - 0.012 15.1 0.3 0.16 11.3 0.1 2.1 1 1 1 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DSPc PF00782.20 EMR68910.1 - 9.4e-12 44.9 0.1 4.5e-07 29.8 0.1 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Ank_4 PF13637.6 EMR68911.1 - 0.013 16.1 0.1 0.049 14.2 0.1 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.28 EMR68912.1 - 2.3e-44 152.4 0.1 3e-44 152.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EMR68912.1 - 1.1e-06 29.0 29.8 0.0016 18.8 11.6 2.7 2 0 0 2 2 2 2 Chitin recognition protein Peptidase_S8 PF00082.22 EMR68913.1 - 2.2e-07 30.4 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Subtilase family Polysacc_synt_C PF14667.6 EMR68914.1 - 8.9e-05 22.6 0.8 8.9e-05 22.6 0.8 4.3 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 EMR68914.1 - 0.00022 20.9 20.8 0.011 15.4 2.6 3.5 3 1 0 3 3 3 2 MatE DUF647 PF04884.14 EMR68915.1 - 5.1e-95 317.7 8.9 3e-94 315.2 8.9 1.9 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Metallophos PF00149.28 EMR68916.1 - 1.7e-07 31.9 5.2 0.00027 21.5 0.0 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase zf-C2H2_aberr PF17017.5 EMR68917.1 - 0.056 13.6 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger PIF2 PF04631.12 EMR68917.1 - 0.13 11.1 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Per os infectivity factor 2 zf-C2H2_4 PF13894.6 EMR68917.1 - 3.3 8.8 7.6 0.52 11.3 0.9 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger FMO-like PF00743.19 EMR68918.1 - 6.1e-30 104.1 0.0 9.9e-21 73.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR68918.1 - 2.8e-11 43.2 0.8 1.7e-06 27.6 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR68918.1 - 2.2e-07 30.4 0.0 0.0082 15.4 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR68918.1 - 0.00013 22.0 0.3 0.0027 17.7 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMR68918.1 - 0.00023 21.3 0.0 0.0005 20.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR68918.1 - 0.00045 19.9 2.2 0.028 14.0 0.4 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EMR68918.1 - 0.0038 16.4 0.3 1.1 8.3 0.0 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EMR68918.1 - 0.0066 15.2 0.2 0.011 14.5 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EMR68918.1 - 0.042 13.1 0.2 0.6 9.3 0.1 2.3 3 0 0 3 3 3 0 Thi4 family Glu_dehyd_C PF16912.5 EMR68918.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus N2227 PF07942.12 EMR68919.1 - 5.8e-92 307.7 0.0 4.4e-91 304.8 0.0 1.9 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EMR68919.1 - 0.00024 21.0 0.2 0.0011 18.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Spt20 PF12090.8 EMR68919.1 - 0.0033 17.1 2.2 0.0046 16.6 2.2 1.2 1 0 0 1 1 1 1 Spt20 family Methyltransf_12 PF08242.12 EMR68919.1 - 0.0044 17.7 0.0 0.0044 17.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Androgen_recep PF02166.16 EMR68919.1 - 0.0051 15.7 1.3 0.0051 15.7 1.3 2.0 2 0 0 2 2 2 1 Androgen receptor Methyltransf_11 PF08241.12 EMR68919.1 - 0.019 15.6 0.9 0.039 14.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF2722 PF10846.8 EMR68919.1 - 0.019 13.9 1.5 0.024 13.6 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 EMR68919.1 - 0.04 14.0 8.0 0.083 13.0 8.0 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 B56 PF01603.20 EMR68920.1 - 4.5e-193 641.9 6.9 5.2e-193 641.7 6.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EMR68920.1 - 0.00038 20.4 2.3 0.22 11.4 0.0 2.5 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Dynamin_N PF00350.23 EMR68920.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Dynamin family Drc1-Sld2 PF11719.8 EMR68921.1 - 2.3 7.7 11.3 3 7.3 11.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nitroreductase PF00881.24 EMR68922.1 - 1.4e-16 61.0 0.0 1.8e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PV-1 PF06637.11 EMR68923.1 - 0.0064 15.4 1.9 0.0081 15.0 1.9 1.1 1 0 0 1 1 1 1 PV-1 protein (PLVAP) TF_AP-2 PF03299.14 EMR68923.1 - 0.031 14.2 2.6 0.045 13.7 2.6 1.3 1 0 0 1 1 1 0 Transcription factor AP-2 SHE3 PF17078.5 EMR68923.1 - 0.038 13.7 1.1 0.06 13.1 1.1 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 PKcGMP_CC PF16808.5 EMR68923.1 - 0.32 10.9 2.7 0.64 9.9 2.7 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FUSC PF04632.12 EMR68923.1 - 6.9 5.1 7.6 8.7 4.7 7.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Asparaginase PF00710.20 EMR68924.1 - 5.7e-59 198.9 0.0 1.2e-58 197.9 0.0 1.5 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EMR68924.1 - 3.8e-22 78.7 0.0 1e-21 77.3 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EMR68924.1 - 4.1e-07 30.5 0.0 0.037 14.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR68924.1 - 1.1e-06 29.0 0.1 0.032 14.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EMR68924.1 - 3.1e-06 27.4 0.0 0.3 11.6 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EMR68924.1 - 0.0014 18.9 0.1 3.7 8.4 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EMR68924.1 - 0.051 13.9 0.6 5.1 7.5 0.1 2.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) HEAT_EZ PF13513.6 EMR68925.1 - 2.1e-29 101.5 20.9 3.8e-15 56.0 0.0 11.4 9 2 4 13 13 13 7 HEAT-like repeat HEAT PF02985.22 EMR68925.1 - 5.6e-27 91.5 9.6 7.3e-05 22.7 0.0 10.6 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 EMR68925.1 - 7.6e-21 74.3 4.0 7.1e-06 26.3 0.0 7.6 5 3 3 8 8 7 5 HEAT repeats Cnd1 PF12717.7 EMR68925.1 - 1.6e-13 51.0 0.2 0.045 13.8 0.0 4.9 4 0 0 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EMR68925.1 - 3.7e-10 40.3 0.6 0.23 12.1 0.0 6.3 5 1 2 7 7 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EMR68925.1 - 9.1e-08 31.6 12.8 0.00055 19.2 0.1 5.0 5 2 1 6 6 6 3 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 EMR68925.1 - 6.7e-07 29.1 0.2 0.7 9.4 0.0 5.9 5 1 1 6 6 6 2 CLASP N terminal IBN_N PF03810.19 EMR68925.1 - 2e-06 27.6 0.8 0.00053 19.8 0.1 4.1 3 1 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EMR68925.1 - 5.8e-06 25.1 0.0 0.014 14.0 0.1 3.0 2 2 0 3 3 3 2 Adaptin N terminal region RTP1_C1 PF10363.9 EMR68925.1 - 0.00019 21.6 0.0 0.025 14.7 0.0 3.4 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EMR68925.1 - 0.00052 20.0 6.4 3.4 7.8 0.0 6.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 EMR68925.1 - 0.0007 19.5 0.0 0.11 12.5 0.0 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) TAF6_C PF07571.13 EMR68925.1 - 0.012 16.0 0.0 19 5.7 0.0 4.3 5 2 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain TetR_C_30 PF17939.1 EMR68925.1 - 0.018 15.2 0.1 0.25 11.6 0.0 2.9 4 0 0 4 4 3 0 Tetracyclin repressor-like, C-terminal domain RIX1 PF08167.12 EMR68925.1 - 0.052 13.3 0.2 12 5.6 0.0 4.5 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.16 EMR68925.1 - 1.3 9.9 7.0 52 4.9 0.0 5.3 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat DUF1876 PF08962.11 EMR68926.1 - 0.046 13.7 0.8 1.4 9.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1876) Guanylate_cyc PF00211.20 EMR68926.1 - 0.2 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain PS_Dcarbxylase PF02666.15 EMR68927.1 - 5.1e-75 251.4 0.0 3e-74 248.9 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase mIF3 PF14877.6 EMR68928.1 - 3e-06 27.0 0.0 7.6e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial translation initiation factor IF3_C PF00707.22 EMR68928.1 - 6.3e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain SDA1 PF05285.12 EMR68928.1 - 7.2e-05 22.4 7.9 0.00011 21.8 7.9 1.3 1 0 0 1 1 1 1 SDA1 RNA_pol_3_Rpc31 PF11705.8 EMR68928.1 - 0.0032 17.8 7.4 0.0032 17.8 7.4 1.8 2 1 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 EMR68928.1 - 0.019 13.1 4.3 0.025 12.7 4.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi IF3_N PF05198.16 EMR68928.1 - 0.054 13.8 0.0 6.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain Nop14 PF04147.12 EMR68928.1 - 0.069 11.4 6.8 0.091 11.0 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 EMR68928.1 - 0.079 12.6 4.6 0.049 13.3 2.4 1.9 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 EMR68928.1 - 0.12 10.7 3.4 0.13 10.5 3.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 EMR68928.1 - 0.7 9.7 6.9 0.24 11.2 3.5 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 EMR68928.1 - 0.72 9.1 6.8 1.1 8.5 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EMR68928.1 - 3.9 7.9 14.2 9.2 6.7 14.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Questin_oxidase PF14027.6 EMR68929.1 - 5.6e-87 292.5 0.2 6.9e-87 292.1 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like Ald_deCOase PF11266.8 EMR68929.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase adh_short_C2 PF13561.6 EMR68930.1 - 2.7e-46 158.0 4.9 3.3e-46 157.7 4.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR68930.1 - 7e-43 146.4 0.9 7e-43 146.4 0.9 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMR68930.1 - 3e-08 33.8 1.0 4.8e-08 33.1 1.0 1.3 1 0 0 1 1 1 1 KR domain Arm PF00514.23 EMR68931.1 - 1.3e-70 231.5 32.7 1.4e-13 50.3 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EMR68931.1 - 6.1e-17 61.7 10.5 0.00013 22.3 0.2 7.0 5 2 2 7 7 7 4 HEAT-like repeat HEAT_2 PF13646.6 EMR68931.1 - 9.4e-16 58.0 8.8 0.00011 22.5 0.1 6.0 3 2 1 5 5 5 4 HEAT repeats HEAT PF02985.22 EMR68931.1 - 9.5e-13 47.2 15.4 0.066 13.5 0.3 7.7 9 0 0 9 9 7 4 HEAT repeat Adaptin_N PF01602.20 EMR68931.1 - 1.7e-12 46.7 6.7 1.6e-07 30.3 0.2 2.8 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 EMR68931.1 - 2e-11 43.8 4.5 1.2e-07 31.5 1.6 2.6 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 EMR68931.1 - 8.9e-09 35.1 0.9 9.5e-05 21.8 0.4 3.1 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.12 EMR68931.1 - 6.6e-08 31.2 0.6 1.3e-07 30.2 0.6 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 EMR68931.1 - 5.5e-05 23.3 7.1 0.066 13.2 0.3 4.1 2 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EMR68931.1 - 0.00018 21.5 5.7 1.3 9.0 0.0 4.1 2 1 2 4 4 4 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EMR68931.1 - 0.00027 21.0 1.1 23 5.1 0.0 4.7 2 1 5 7 7 6 0 V-ATPase subunit H DUF5578 PF17741.1 EMR68931.1 - 0.00027 20.4 4.7 1.6 8.1 0.0 4.8 1 1 3 5 5 5 2 Family of unknown function (DUF5578) IFRD PF05004.13 EMR68931.1 - 0.00052 19.2 1.3 1.9 7.5 0.1 3.7 2 1 1 3 3 3 2 Interferon-related developmental regulator (IFRD) Atx10homo_assoc PF09759.9 EMR68931.1 - 0.023 14.7 6.2 3.5 7.7 0.5 4.7 4 2 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 EMR68931.1 - 0.045 14.4 5.2 93 4.2 0.1 6.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 EMR68931.1 - 0.086 12.8 0.9 14 5.6 0.1 3.2 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Vpu PF00558.19 EMR68931.1 - 0.089 12.6 1.2 0.19 11.5 0.2 2.0 2 0 0 2 2 2 0 Vpu protein Vac14_Fab1_bd PF12755.7 EMR68931.1 - 0.11 13.2 0.0 4 8.1 0.0 3.1 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Exo_endo_phos PF03372.23 EMR68932.1 - 5.5e-05 22.8 0.1 8.5e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tyrosinase PF00264.20 EMR68933.1 - 1.4e-44 153.0 0.1 2.1e-44 152.5 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 EMR68934.1 - 3.3e-13 49.3 12.7 4.5e-10 39.0 7.7 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TraL PF07178.11 EMR68934.1 - 0.22 12.0 0.2 0.22 12.0 0.2 2.6 3 0 0 3 3 3 0 TraL protein TRAM_LAG1_CLN8 PF03798.16 EMR68935.1 - 1.2e-35 123.1 14.2 1.2e-35 123.1 14.2 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EMR68935.1 - 2.4e-23 81.5 0.0 6.6e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein PAC4 PF16093.5 EMR68936.1 - 1.4e-24 86.1 0.0 1.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Peptidase_S26 PF10502.9 EMR68937.1 - 3.9e-05 23.5 0.0 0.02 14.6 0.0 2.2 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 EMR68937.1 - 0.0025 17.7 0.0 0.0088 16.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like CBS PF00571.28 EMR68938.1 - 9e-18 64.5 6.9 8.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 CBS domain NAP PF00956.18 EMR68939.1 - 1.3e-32 113.1 15.7 5.9e-30 104.3 9.6 2.3 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DNA_mis_repair PF01119.19 EMR68939.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain BT1 PF03092.16 EMR68939.1 - 0.14 10.4 0.1 0.2 9.9 0.1 1.1 1 0 0 1 1 1 0 BT1 family DASH_Ask1 PF08655.10 EMR68939.1 - 0.14 12.1 0.0 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Ask1 DUF4611 PF15387.6 EMR68939.1 - 0.56 10.5 21.0 0.17 12.1 3.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Voldacs PF03517.13 EMR68939.1 - 2 8.5 12.9 4.1 7.5 12.9 1.5 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Glyco_hydro_76 PF03663.14 EMR68940.1 - 9e-157 522.3 12.9 1e-156 522.1 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMR68940.1 - 0.011 14.9 13.6 0.049 12.7 0.6 3.3 2 1 1 4 4 4 0 Glycosyl Hydrolase Family 88 CD99L2 PF12301.8 EMR68941.1 - 0.2 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 F-box-like PF12937.7 EMR68942.1 - 3.1e-05 23.8 0.7 6.9e-05 22.7 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EMR68942.1 - 0.031 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain Glyco_hydro_76 PF03663.14 EMR68943.1 - 6e-126 420.9 19.2 7.2e-126 420.6 19.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 adh_short_C2 PF13561.6 EMR68944.1 - 6e-56 189.6 3.5 7e-56 189.4 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR68944.1 - 1e-47 162.1 0.4 1.3e-47 161.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR68944.1 - 4.1e-13 49.6 1.2 5.6e-13 49.2 1.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR68944.1 - 0.0037 16.7 0.0 0.57 9.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR68944.1 - 0.025 14.5 0.9 0.056 13.3 0.9 1.6 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR68944.1 - 0.066 12.6 0.0 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EMR68944.1 - 0.14 12.0 0.2 0.81 9.5 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 EMR68946.1 - 3.6e-11 43.2 0.0 5.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR68946.1 - 1e-08 35.7 0.0 2.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR68946.1 - 2.3e-08 34.6 0.0 6.8e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR68946.1 - 4.8e-07 30.4 0.0 2.1e-06 28.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR68946.1 - 0.00027 20.4 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EMR68946.1 - 0.00031 20.5 0.0 0.00069 19.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 EMR68947.1 - 3.7e-12 46.1 0.0 4.9e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR68947.1 - 8.7e-12 45.1 0.6 1.1e-11 44.7 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 EMR68947.1 - 0.0031 16.9 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EMR68947.1 - 0.0074 15.8 0.0 0.021 14.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EMR68947.1 - 0.015 15.4 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 EMR68947.1 - 0.025 14.1 0.3 0.081 12.5 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 EMR68947.1 - 0.044 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 EMR68948.1 - 2e-13 50.0 0.0 3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR68948.1 - 2.6e-09 37.0 12.3 4.4e-09 36.3 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 EMR68948.1 - 0.05 12.1 0.2 0.084 11.3 0.2 1.3 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B ACOX PF01756.19 EMR68949.1 - 9.6e-46 155.6 1.8 1.1e-45 155.4 0.0 2.0 3 0 0 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EMR68949.1 - 7.2e-29 100.9 0.1 1.4e-28 99.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EMR68949.1 - 2.8e-11 43.5 0.0 1.5e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EMR68949.1 - 4.7e-05 23.6 0.1 0.0054 16.9 0.0 2.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain BOP1NT PF08145.12 EMR68950.1 - 5.2e-106 354.3 8.8 7.4e-106 353.8 8.8 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EMR68950.1 - 2.9e-24 84.9 9.4 1.8e-09 38.1 0.6 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR68950.1 - 2.4e-08 34.1 0.0 0.0043 17.3 0.0 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EMR68950.1 - 0.052 11.9 0.0 0.2 9.9 0.0 1.7 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_M43 PF05572.13 EMR68951.1 - 1.2e-12 48.0 0.0 2.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EMR68951.1 - 2.1e-07 31.3 0.1 3.8e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EMR68951.1 - 0.00017 21.3 0.1 0.00042 20.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EMR68951.1 - 0.00043 20.2 0.5 0.00059 19.8 0.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EMR68951.1 - 0.0033 16.4 2.2 0.0047 15.9 0.9 1.8 2 1 0 3 3 3 1 Peptidase M66 Reprolysin_3 PF13582.6 EMR68951.1 - 0.0053 17.3 0.4 0.013 16.0 0.3 1.8 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EMR68951.1 - 0.0098 15.8 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 Matrixin DUF4953 PF16313.5 EMR68951.1 - 0.02 14.1 0.4 0.037 13.2 0.1 1.5 2 0 0 2 2 2 0 Met-zincin MFS_1 PF07690.16 EMR68952.1 - 6.9e-33 114.0 48.4 6.8e-31 107.5 48.6 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR68952.1 - 1.5e-09 36.9 11.2 2e-09 36.4 11.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4407 PF14362.6 EMR68952.1 - 0.1 12.0 2.3 0.22 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2523 PF10734.9 EMR68952.1 - 2.3 8.9 22.2 4.2 8.0 0.1 5.4 4 1 1 5 5 5 0 Protein of unknown function (DUF2523) F-box-like PF12937.7 EMR68953.1 - 3.6e-09 36.4 0.3 1.3e-08 34.6 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR68953.1 - 3e-07 30.1 0.1 8e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 EMR68953.1 - 0.0033 17.4 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain Guanylate_kin PF00625.21 EMR68953.1 - 0.19 11.4 0.7 1.9 8.1 0.9 2.1 2 0 0 2 2 2 0 Guanylate kinase Transglut_core PF01841.19 EMR68954.1 - 4.6e-13 49.6 0.1 8.4e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 EMR68954.1 - 0.0027 18.7 0.0 0.008 17.2 0.0 1.9 2 0 0 2 2 2 1 Papain fold toxin 1, glutamine deamidase DUF3405 PF11885.8 EMR68955.1 - 2e-115 386.4 7.5 3.6e-114 382.2 7.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) UvrD_C_2 PF13538.6 EMR68955.1 - 0.085 12.7 0.5 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Ank_2 PF12796.7 EMR68956.1 - 2.1e-51 172.4 4.7 1.6e-13 51.0 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR68956.1 - 2.9e-39 132.6 7.4 1.5e-10 41.1 0.1 6.5 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR68956.1 - 3.2e-37 126.4 0.3 8.6e-09 35.8 0.0 6.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR68956.1 - 7.8e-35 115.0 6.3 0.00068 19.9 0.1 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 EMR68956.1 - 3.6e-30 103.1 14.9 2.9e-05 24.3 0.3 8.2 8 0 0 8 8 8 6 Ankyrin repeat Glyco_hyd_65N_2 PF14498.6 EMR68957.1 - 8.7e-59 199.2 0.0 1.2e-58 198.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain MOR2-PAG1_C PF14225.6 EMR68958.1 - 2.9e-89 299.3 2.3 3.3e-89 299.1 0.4 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EMR68958.1 - 3.5e-37 127.7 3.7 1.9e-19 68.9 0.0 3.3 3 1 0 3 3 3 3 Cell morphogenesis central region MOR2-PAG1_N PF14222.6 EMR68958.1 - 3.1e-13 49.5 0.0 5.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal Katanin_con80 PF13925.6 EMR68958.1 - 0.065 13.3 0.3 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 con80 domain of Katanin Pmp3 PF01679.17 EMR68959.1 - 1.2e-20 73.4 7.1 1.7e-20 72.9 7.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DIM1 PF02966.16 EMR68960.1 - 1.5e-70 235.1 0.3 1.7e-70 234.9 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EMR68960.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin RIO1 PF01163.22 EMR68961.1 - 9e-42 142.8 0.6 1.4e-29 103.0 0.0 2.6 1 1 2 3 3 3 2 RIO1 family Rio2_N PF09202.11 EMR68961.1 - 2.3e-22 79.0 0.0 5.8e-19 68.1 0.0 2.7 2 0 0 2 2 2 2 Rio2, N-terminal Kdo PF06293.14 EMR68961.1 - 1.2e-06 28.0 0.1 2.7e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR68961.1 - 1.6e-06 28.2 5.2 0.0026 17.7 2.8 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family HSP90 PF00183.18 EMR68961.1 - 0.18 10.7 5.7 0.31 9.9 5.7 1.3 1 0 0 1 1 1 0 Hsp90 protein CobT PF06213.12 EMR68961.1 - 0.34 10.3 14.3 0.91 8.9 0.6 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT TraH_2 PF06871.11 EMR68961.1 - 1 8.9 3.3 0.27 10.8 0.2 1.6 2 0 0 2 2 2 0 TraH_2 SmAKAP PF15127.6 EMR68961.1 - 1.3 10.3 4.5 2.8 9.2 4.5 1.5 1 0 0 1 1 1 0 Small membrane A-kinase anchor protein Prothymosin PF03247.14 EMR68961.1 - 1.4 9.4 30.9 2.9 8.4 9.4 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Na_trans_assoc PF06512.13 EMR68961.1 - 4.3 7.6 9.3 0.12 12.6 0.5 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated Npa1 PF11707.8 EMR68962.1 - 3.3e-105 352.2 0.1 8.5e-105 350.8 0.0 1.7 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EMR68962.1 - 5.1e-59 199.2 0.0 3.7e-58 196.4 0.0 2.5 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 HEAT_EZ PF13513.6 EMR68962.1 - 0.0046 17.4 0.8 0.23 12.0 0.3 4.2 5 0 0 5 5 5 1 HEAT-like repeat SRP9-21 PF05486.12 EMR68962.1 - 0.044 14.2 0.0 10 6.6 0.1 2.6 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Arm PF00514.23 EMR68962.1 - 0.045 13.8 0.1 24 5.2 0.0 3.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Alpha_kinase PF02816.18 EMR68963.1 - 7.3e-49 166.4 0.0 9.1e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Stc1 PF12898.7 EMR68963.1 - 0.015 15.8 0.3 0.032 14.8 0.3 1.6 1 0 0 1 1 1 0 Stc1 domain DUF4551 PF15087.6 EMR68964.1 - 0.85 8.4 5.8 1.1 8.0 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Lon_C PF05362.13 EMR68965.1 - 7.5e-64 215.0 0.1 1.3e-63 214.2 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EMR68965.1 - 1e-25 90.8 0.0 2.6e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EMR68965.1 - 1.4e-22 80.5 0.0 1.9e-21 76.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EMR68965.1 - 1.2e-09 38.0 0.7 2.3e-07 30.7 0.0 3.0 3 1 0 3 3 3 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EMR68965.1 - 8.1e-08 32.4 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMR68965.1 - 3.6e-06 27.5 0.2 1.2e-05 25.7 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 EMR68965.1 - 3.3e-05 23.7 0.2 9.8e-05 22.1 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR68965.1 - 0.00013 22.2 0.0 0.0091 16.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EMR68965.1 - 0.00019 21.3 0.0 0.00047 20.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EMR68965.1 - 0.0017 18.9 1.9 0.031 14.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EMR68965.1 - 0.0028 17.8 0.0 0.011 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EMR68965.1 - 0.0034 17.1 0.0 0.0095 15.7 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EMR68965.1 - 0.0043 16.3 0.2 0.0099 15.1 0.2 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EMR68965.1 - 0.0079 16.4 0.1 0.073 13.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EMR68965.1 - 0.014 15.3 0.0 0.26 11.2 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 EMR68965.1 - 0.018 15.6 0.0 0.085 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMR68965.1 - 0.018 15.4 0.0 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 EMR68965.1 - 0.03 14.3 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EMR68965.1 - 0.038 13.4 0.1 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FAM91_N PF14647.6 EMR68965.1 - 0.057 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 FAM91 N-terminus HalX PF08663.10 EMR68965.1 - 0.063 13.6 2.2 17 5.8 0.2 3.4 3 0 0 3 3 3 0 HalX domain TsaE PF02367.17 EMR68965.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EMR68965.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prefoldin_3 PF13758.6 EMR68965.1 - 1.4 9.0 4.7 4.2 7.5 0.2 3.3 3 0 0 3 3 3 0 Prefoldin subunit Sec1 PF00995.23 EMR68966.1 - 4.2e-94 316.8 0.0 2.1e-90 304.7 0.0 2.0 1 1 1 2 2 2 2 Sec1 family Apo-CIII PF05778.12 EMR68966.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) CAF20 PF17052.5 EMR68967.1 - 6.9 6.8 13.7 0.065 13.4 4.1 2.4 2 1 0 3 3 3 0 Cap associated factor adh_short PF00106.25 EMR68968.1 - 3.5e-16 59.3 0.0 9.7e-15 54.5 0.0 2.9 2 2 1 3 3 3 1 short chain dehydrogenase Epimerase PF01370.21 EMR68968.1 - 1.4e-07 31.2 0.0 4.9e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 EMR68968.1 - 2.4e-06 27.3 0.0 2.3e-05 24.1 0.0 2.5 3 1 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR68968.1 - 7.7e-06 25.9 1.0 3e-05 24.0 0.0 2.1 2 1 1 3 3 3 1 KR domain GDP_Man_Dehyd PF16363.5 EMR68968.1 - 0.16 11.3 2.7 1.4 8.3 0.0 2.7 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Synaptobrevin PF00957.21 EMR68969.1 - 1.7e-31 107.8 0.4 2.3e-31 107.4 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EMR68969.1 - 8.7e-27 93.0 0.0 1.7e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain RRM_1 PF00076.22 EMR68970.1 - 2.5e-20 72.1 0.0 8.1e-11 41.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 EMR68971.1 - 2.4e-65 220.2 0.0 3.6e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EMR68971.1 - 3.3e-36 124.6 1.9 4.3e-36 124.2 0.3 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EMR68971.1 - 1.4e-10 41.8 0.1 8.7e-06 26.4 0.0 3.2 2 1 1 3 3 3 2 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EMR68971.1 - 0.042 14.1 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 Flavodoxin domain Pkinase PF00069.25 EMR68972.1 - 1.4e-05 24.6 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EMR68972.1 - 1.8e-05 24.2 0.1 4.5e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR68972.1 - 0.59 10.0 5.0 0.57 10.1 0.1 2.6 1 1 1 3 3 3 0 Phosphotransferase enzyme family GHMP_kinases_N PF00288.26 EMR68973.1 - 1.9e-15 56.8 0.1 5.1e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMR68973.1 - 6.7e-08 32.8 0.2 1.8e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal PALP PF00291.25 EMR68974.1 - 6.9e-59 199.7 7.3 1.2e-58 198.8 7.3 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1g PF09334.11 EMR68975.1 - 2.7e-88 296.4 0.0 7.8e-87 291.5 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EMR68975.1 - 1.1e-16 60.2 0.1 2.5e-06 26.0 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMR68975.1 - 4.5e-05 23.4 0.0 8.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EMR68975.1 - 8.3e-05 22.1 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain SNF2_N PF00176.23 EMR68976.1 - 7.3e-38 130.2 0.6 5.5e-37 127.3 0.5 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR68976.1 - 2.7e-16 59.9 0.0 1.6e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EMR68976.1 - 1.7e-05 24.6 14.1 3.3e-05 23.6 14.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EMR68976.1 - 3.2e-05 24.0 0.8 9.5e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 EMR68976.1 - 0.0005 19.9 12.3 0.00098 18.9 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMR68976.1 - 0.001 19.3 13.8 0.0026 18.1 13.8 1.7 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.29 EMR68976.1 - 0.0035 17.1 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 EMR68976.1 - 0.019 14.8 13.1 0.039 13.8 13.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 EMR68976.1 - 0.024 13.8 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 EMR68976.1 - 0.56 10.2 12.6 1.2 9.1 12.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_10 PF16685.5 EMR68976.1 - 0.77 9.9 7.3 1.9 8.7 7.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EMR68976.1 - 1.4 8.9 13.0 2.7 7.9 13.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AT_hook PF02178.19 EMR68976.1 - 2 8.6 7.1 0.32 11.0 2.0 2.6 2 0 0 2 2 2 0 AT hook motif MRC1 PF09444.10 EMR68976.1 - 5.8 7.4 28.0 1.8 9.1 5.6 3.7 2 1 1 3 3 3 0 MRC1-like domain zf-RING_UBOX PF13445.6 EMR68976.1 - 8.2 6.6 12.8 17 5.5 12.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger NAD_binding_9 PF13454.6 EMR68977.1 - 5.7e-08 32.9 0.1 6.9e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMR68977.1 - 2.6e-07 30.8 0.8 3.3e-07 30.4 0.2 1.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR68977.1 - 2.7e-05 23.5 0.1 2.8e-05 23.5 0.1 1.0 1 0 0 1 1 1 1 Thi4 family FMO-like PF00743.19 EMR68977.1 - 8.2e-05 21.2 0.0 9.1e-05 21.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.24 EMR68977.1 - 0.0026 17.4 0.5 0.0029 17.2 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EMR68977.1 - 0.0042 15.9 0.0 0.005 15.7 0.0 1.0 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 EMR68977.1 - 0.0052 16.0 0.1 0.0058 15.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR68977.1 - 0.0091 15.3 0.1 0.0096 15.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR68977.1 - 0.0097 15.2 0.1 0.0099 15.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EMR68977.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EMR68977.1 - 0.011 14.5 0.9 0.013 14.2 0.9 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EMR68977.1 - 0.042 14.4 0.5 0.068 13.7 0.5 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMR68977.1 - 0.047 13.0 0.7 0.048 13.0 0.7 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EMR68977.1 - 0.052 13.6 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EMR68977.1 - 0.069 12.5 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.14 EMR68977.1 - 0.081 11.8 0.3 0.084 11.7 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Ish1 PF10281.9 EMR68978.1 - 1.5e-06 28.4 0.1 2.1e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DNA_meth_N PF18284.1 EMR68978.1 - 0.092 12.7 0.9 0.14 12.1 0.9 1.4 1 0 0 1 1 1 0 DNA methylase N-terminal domain NTF2 PF02136.20 EMR68979.1 - 0.06 13.9 0.1 0.55 10.8 0.2 2.1 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Acetyltransf_3 PF13302.7 EMR68980.1 - 4.1e-16 59.9 0.0 8.7e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR68980.1 - 2.5e-06 27.3 0.1 0.01 15.8 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.25 EMR68980.1 - 0.00079 19.7 0.0 0.24 11.7 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EMR68980.1 - 0.0055 16.4 0.0 0.65 9.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMR68980.1 - 0.033 14.3 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_L38e PF01781.18 EMR68981.1 - 3.8e-34 116.6 2.7 4.7e-34 116.3 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Calreticulin PF00262.18 EMR68981.1 - 0.058 12.3 0.1 0.067 12.0 0.1 1.1 1 0 0 1 1 1 0 Calreticulin family Cyclophil_like2 PF18050.1 EMR68981.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 1 0 1 1 1 0 Cyclophilin-like family LRR_6 PF13516.6 EMR68982.1 - 1.4e-05 24.7 0.3 0.48 10.6 0.0 5.3 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 EMR68982.1 - 0.017 15.5 7.2 37 4.9 0.2 6.0 5 3 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMR68982.1 - 0.048 13.4 3.1 0.21 11.3 0.2 3.6 4 1 0 4 4 4 0 Leucine rich repeat DUF4428 PF14471.6 EMR68982.1 - 0.11 12.4 1.1 0.35 10.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) CDC45 PF02724.14 EMR68982.1 - 0.83 7.9 7.3 1.2 7.4 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 EMR68982.1 - 1.7 7.9 15.8 0.11 11.9 10.8 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PGA2 PF07543.12 EMR68982.1 - 6.6 6.7 13.8 15 5.6 13.8 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Methyltransf_2 PF00891.18 EMR68985.1 - 2.4e-26 92.3 0.0 3e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EMR68985.1 - 0.00013 22.5 0.0 0.00023 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR68985.1 - 0.00074 20.2 0.0 0.0012 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EMR68985.1 - 0.0052 16.3 0.0 0.0063 16.0 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 EMR68985.1 - 0.023 14.4 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PPTA PF01239.22 EMR68986.1 - 8.6e-38 127.0 18.6 1.2e-07 31.2 0.2 6.3 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat KIX PF02172.16 EMR68986.1 - 0.034 14.4 0.0 0.087 13.1 0.0 1.6 1 0 0 1 1 1 0 KIX domain TPR_14 PF13428.6 EMR68986.1 - 0.075 13.9 3.3 21 6.3 1.2 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMR68986.1 - 0.11 13.2 0.8 0.41 11.4 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMR68986.1 - 1.6 8.9 3.7 1.8 8.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1772 PF08592.11 EMR68987.1 - 7.1e-29 100.9 4.9 1.1e-28 100.2 4.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PCI PF01399.27 EMR68988.1 - 1.2e-12 48.3 0.0 2e-11 44.3 0.0 2.2 1 1 1 2 2 2 1 PCI domain HrpB1_HrpK PF09613.10 EMR68988.1 - 0.072 12.7 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) MbeD_MobD PF04899.12 EMR68988.1 - 0.12 12.5 0.2 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 MbeD/MobD like DUF2946 PF11162.8 EMR68989.1 - 0.29 11.8 8.9 0.41 11.3 6.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) SelP_N PF04592.14 EMR68989.1 - 3.6 6.9 11.1 0.72 9.2 7.3 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Amidohydro_3 PF07969.11 EMR68990.1 - 0.0021 17.6 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Ribosomal_L18A PF01775.17 EMR68991.1 - 1.3e-55 186.7 0.4 1.6e-55 186.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Spore_YtfJ PF09579.10 EMR68992.1 - 1.9 8.7 5.2 3.7 7.8 5.2 1.4 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) DUF5099 PF17025.5 EMR68993.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) UDG PF03167.19 EMR68994.1 - 3.4e-21 75.9 0.1 7.2e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Mito_carr PF00153.27 EMR68995.1 - 1.3e-36 124.4 0.6 8.8e-19 67.2 0.1 3.1 2 1 0 2 2 2 2 Mitochondrial carrier protein Hydantoinase_B PF02538.14 EMR68996.1 - 1.9e-187 623.8 0.1 2.5e-187 623.4 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMR68996.1 - 1.5e-90 303.4 0.4 3.8e-90 302.1 0.0 1.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMR68996.1 - 6.8e-52 175.7 0.5 5.6e-50 169.5 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BTB PF00651.31 EMR68997.1 - 1.1e-09 38.5 0.1 5.9e-09 36.1 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.15 EMR68997.1 - 0.015 15.4 0.0 0.066 13.4 0.0 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Cpn60_TCP1 PF00118.24 EMR68998.1 - 2.2e-157 524.6 4.1 2.5e-157 524.4 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EMR68998.1 - 0.24 11.6 2.3 14 5.8 0.1 3.1 3 0 0 3 3 3 0 Enolase, N-terminal domain MFS_1 PF07690.16 EMR68999.1 - 1e-36 126.6 23.6 1e-36 126.6 23.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 EMR69000.1 - 0.011 15.6 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 EMR69000.1 - 0.086 11.6 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Chromosome_seg PF13889.6 EMR69001.1 - 0.0034 17.5 0.2 0.0089 16.2 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation during meiosis Herpes_LMP2 PF07415.11 EMR69001.1 - 0.17 10.7 0.2 0.22 10.2 0.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Fungal_trans PF04082.18 EMR69002.1 - 2.9e-14 52.7 0.0 5.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR69002.1 - 9.9e-07 28.8 6.6 9.9e-07 28.8 6.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eRF1_1 PF03463.15 EMR69002.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 eRF1 domain 1 F-box-like PF12937.7 EMR69003.1 - 4.2e-11 42.6 0.1 8.3e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR69003.1 - 5.4e-05 22.9 0.2 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain Ku_C PF03730.14 EMR69003.1 - 0.11 13.2 1.6 6.4 7.6 0.1 2.6 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Acetyltransf_3 PF13302.7 EMR69004.1 - 3.1e-31 108.9 0.1 5.3e-31 108.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR69004.1 - 0.00066 19.9 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EMR69004.1 - 0.02 14.6 0.0 10 5.8 0.0 2.8 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR69004.1 - 0.027 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Amidohydro_1 PF01979.20 EMR69005.1 - 4.4e-14 52.6 0.0 4.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR69005.1 - 1e-09 38.4 0.0 2.5e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family HTH_23 PF13384.6 EMR69005.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain SLATT_fungal PF18142.1 EMR69006.1 - 8.4e-29 100.0 3.0 3.7e-28 97.9 0.0 2.2 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain CorA PF01544.18 EMR69006.1 - 0.067 12.5 2.2 0.11 11.8 2.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mer2 PF09074.10 EMR69006.1 - 0.15 11.9 1.8 0.23 11.2 1.8 1.3 1 0 0 1 1 1 0 Mer2 ATP-synt_ab_C PF00306.27 EMR69006.1 - 0.27 11.6 1.6 14 6.1 0.9 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain ISG65-75 PF11727.8 EMR69006.1 - 9.1 5.4 11.2 5.6 6.1 1.8 1.8 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF1708 PF08101.11 EMR69007.1 - 1.4e-144 482.4 0.0 6.8e-120 401.1 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1708) DUF3402 PF11882.8 EMR69007.1 - 0.051 12.7 1.5 0.15 11.2 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Inhibitor_I9 PF05922.16 EMR69008.1 - 0.003 18.2 0.1 0.0052 17.4 0.1 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 DIOX_N PF14226.6 EMR69009.1 - 1.7e-26 93.3 0.0 2.8e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR69009.1 - 1.2e-20 73.9 0.0 3.6e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosom_S12_S23 PF00164.25 EMR69010.1 - 4.5e-51 171.3 0.8 5.6e-51 171.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 GST_N_3 PF13417.6 EMR69011.1 - 1.2e-13 51.3 0.0 2.1e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMR69011.1 - 7.8e-12 45.4 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR69011.1 - 3.8e-11 43.1 0.0 6.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR69011.1 - 1.4e-09 38.1 0.0 3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR69011.1 - 1.2e-07 31.8 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR69011.1 - 0.00021 21.3 0.3 0.00045 20.2 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HOOK PF05622.12 EMR69012.1 - 7.1e-12 44.3 68.2 1.8e-11 43.0 46.0 3.1 3 0 0 3 3 3 2 HOOK protein Striatin PF08232.12 EMR69012.1 - 0.00021 21.9 2.1 0.00021 21.9 2.1 4.9 4 2 0 4 4 4 1 Striatin family Cep57_CLD_2 PF14197.6 EMR69012.1 - 0.012 15.7 2.2 0.012 15.7 2.2 8.1 8 1 0 8 8 8 0 Centrosome localisation domain of PPC89 RHH_4 PF13467.6 EMR69012.1 - 0.023 14.6 0.0 3.1 7.8 0.0 3.1 2 0 0 2 2 2 0 Ribbon-helix-helix domain bMG6 PF17962.1 EMR69012.1 - 0.21 11.8 1.5 0.43 10.8 0.2 2.2 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 rve_3 PF13683.6 EMR69012.1 - 2 8.3 4.1 6.3 6.7 0.1 3.7 3 0 0 3 3 3 0 Integrase core domain FAD_binding_4 PF01565.23 EMR69014.1 - 5.7e-26 90.9 0.8 9.6e-26 90.2 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR69014.1 - 0.05 13.7 0.5 0.11 12.6 0.5 1.6 1 0 0 1 1 1 0 Berberine and berberine like MFS_1 PF07690.16 EMR69015.1 - 3.7e-41 141.2 46.5 7.7e-41 140.2 46.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR69015.1 - 2.3e-12 46.1 11.9 3.5e-12 45.6 11.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMR69015.1 - 1.5e-09 37.3 8.2 1.5e-09 37.3 8.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3522 PF12036.8 EMR69015.1 - 0.11 12.8 6.2 0.078 13.3 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) UbiA PF01040.18 EMR69016.1 - 4.7e-40 137.5 17.3 7.8e-40 136.8 17.3 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Nop14 PF04147.12 EMR69017.1 - 0.21 9.8 20.5 0.21 9.8 20.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EMR69017.1 - 4.3 6.7 21.2 4.1 6.7 21.2 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EMR69017.1 - 6 4.8 27.9 6.8 4.7 27.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Gpr1_Fun34_YaaH PF01184.19 EMR69018.1 - 1e-22 80.8 20.5 1.1e-22 80.7 20.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF5315 PF17242.2 EMR69019.1 - 8.6e-27 92.8 1.3 9.3e-27 92.7 0.2 1.6 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) ADH_N PF08240.12 EMR69020.1 - 9.1e-26 89.9 0.3 2.1e-25 88.7 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR69020.1 - 8.5e-15 54.9 0.3 2.3e-14 53.5 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR69020.1 - 6.4e-06 25.8 0.5 0.052 13.0 0.0 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 EMR69020.1 - 0.00028 20.1 1.0 0.00038 19.7 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 EMR69020.1 - 0.0067 16.5 0.3 0.039 14.0 0.0 2.2 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EMR69020.1 - 0.017 13.8 1.4 0.025 13.3 1.4 1.2 1 0 0 1 1 1 0 HI0933-like protein PALP PF00291.25 EMR69020.1 - 0.028 13.8 0.3 0.039 13.4 0.3 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme 3HCDH_N PF02737.18 EMR69020.1 - 0.032 14.1 1.0 0.5 10.2 0.8 2.3 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR69020.1 - 0.086 12.1 1.8 0.17 11.1 0.2 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EMR69020.1 - 0.1 12.8 2.2 0.51 10.6 1.3 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AA_permease_2 PF13520.6 EMR69022.1 - 1.3e-33 116.5 39.6 9e-28 97.2 33.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 EMR69022.1 - 3.9e-08 32.3 25.6 3.9e-08 32.3 25.6 1.6 2 0 0 2 2 2 1 Amino acid permease Gram_pos_anchor PF00746.21 EMR69022.1 - 1 9.3 0.0 1 9.3 0.0 3.0 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Tautomerase_3 PF14832.6 EMR69024.1 - 1.3e-41 142.1 0.1 1.4e-41 141.9 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Glyco_hydro_30 PF02055.16 EMR69025.1 - 2.3e-23 82.7 0.3 3.7e-23 82.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 EMR69025.1 - 6.2e-08 32.7 0.3 1.5e-07 31.5 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 EMR69025.1 - 7.1e-05 22.2 0.3 0.00013 21.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EMR69025.1 - 0.0012 18.6 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 FAD_binding_4 PF01565.23 EMR69026.1 - 9.5e-17 61.0 5.5 4.6e-15 55.6 5.5 2.3 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR69026.1 - 0.00055 20.0 0.1 0.0011 19.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Lactamase_B PF00753.27 EMR69027.1 - 3.9e-18 66.2 0.0 5.1e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMR69027.1 - 0.00013 21.6 0.0 0.00018 21.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMR69027.1 - 0.073 13.0 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase superfamily domain HLH PF00010.26 EMR69028.1 - 3.7e-16 58.8 0.1 6.7e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DNA_methylase PF00145.17 EMR69028.1 - 0.21 10.9 3.1 0.11 11.8 0.9 1.5 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase SLX9 PF15341.6 EMR69028.1 - 0.76 10.2 9.8 0.15 12.5 2.5 2.6 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 Lyase_1 PF00206.20 EMR69029.1 - 1.4e-20 73.9 0.0 2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EMR69029.1 - 6e-15 55.6 0.0 3.4e-14 53.1 0.0 2.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Epimerase PF01370.21 EMR69030.1 - 3.8e-14 52.7 0.0 5.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMR69030.1 - 5.2e-07 29.3 1.8 0.00067 19.2 0.1 2.9 3 0 0 3 3 3 2 short chain dehydrogenase NAD_binding_10 PF13460.6 EMR69030.1 - 2.1e-05 24.5 0.2 3.7e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR69030.1 - 6.6e-05 22.5 0.1 0.00099 18.6 0.1 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMR69030.1 - 0.00066 18.9 0.1 0.00095 18.4 0.1 1.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EMR69030.1 - 0.0015 18.5 0.2 0.0087 16.0 0.2 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EMR69030.1 - 0.0022 17.0 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 EMR69030.1 - 0.014 14.9 2.4 0.39 10.2 0.1 2.9 3 0 0 3 3 3 0 Enoyl-(Acyl carrier protein) reductase DUF3515 PF12028.8 EMR69030.1 - 0.048 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) NmrA PF05368.13 EMR69030.1 - 0.057 13.0 0.2 0.48 9.9 0.1 2.3 3 0 0 3 3 3 0 NmrA-like family Cep57_MT_bd PF06657.13 EMR69032.1 - 1.2e-24 86.6 1.1 1.2e-24 86.6 1.1 6.6 5 1 2 7 7 7 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EMR69032.1 - 7.1e-08 32.4 5.1 7.1e-08 32.4 5.1 7.0 5 2 1 6 6 6 2 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 EMR69032.1 - 0.0039 17.0 31.2 0.0039 17.0 31.2 6.1 2 1 3 5 5 5 2 Coiled-coil region of CCDC155 or KASH JIP_LZII PF16471.5 EMR69032.1 - 0.017 15.3 9.3 0.017 15.3 9.3 8.4 6 2 4 11 11 11 0 JNK-interacting protein leucine zipper II DUF2046 PF09755.9 EMR69032.1 - 0.2 10.9 65.4 0.095 11.9 26.3 4.5 3 1 1 4 4 4 0 Uncharacterized conserved protein H4 (DUF2046) DUF3584 PF12128.8 EMR69032.1 - 0.46 7.9 81.1 0.69 7.3 29.3 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 EMR69032.1 - 0.65 10.1 88.6 0.77 9.8 14.3 6.6 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 EMR69032.1 - 4.1 6.9 74.8 4.8 6.7 18.6 5.5 2 1 3 5 5 5 0 HAUS augmin-like complex subunit 3 Mur_ligase_C PF02875.21 EMR69033.1 - 0.0038 17.4 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Rod_C PF10493.9 EMR69033.1 - 0.1 11.0 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region Ribonuc_2-5A PF06479.12 EMR69033.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease 2-5A Mur_ligase_M PF08245.12 EMR69035.1 - 0.095 12.7 0.0 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Mur ligase middle domain SGTA_dimer PF16546.5 EMR69036.1 - 0.009 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA Methyltransf_23 PF13489.6 EMR69037.1 - 1.3e-22 80.4 0.0 2e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR69037.1 - 1.4e-12 48.1 0.0 5.1e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR69037.1 - 5.2e-11 43.0 0.0 1e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR69037.1 - 1e-09 39.0 0.0 8e-09 36.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR69037.1 - 2.1e-08 34.1 0.0 0.0069 16.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain FtsJ PF01728.19 EMR69037.1 - 0.0001 22.4 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EMR69037.1 - 0.0012 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 EMR69037.1 - 0.024 14.0 0.0 0.43 9.9 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EMR69037.1 - 0.029 13.7 0.0 0.12 11.7 0.0 2.0 3 0 0 3 3 3 0 O-methyltransferase domain CMAS PF02353.20 EMR69037.1 - 0.034 13.4 0.0 0.061 12.6 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 EMR69037.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF3112 PF11309.8 EMR69039.1 - 8.3e-13 48.3 0.1 1.5e-05 24.5 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) ADH_zinc_N PF00107.26 EMR69040.1 - 6e-17 61.8 0.0 8.3e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMR69040.1 - 3.1e-14 52.8 0.0 6.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EMR69040.1 - 6.2e-07 30.5 0.1 1.2e-06 29.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_2 PF00891.18 EMR69042.1 - 9.7e-18 64.2 0.0 1.4e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain K_channel_TID PF07941.11 EMR69042.1 - 0.46 11.0 4.6 0.45 11.0 3.0 1.9 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Methyltransf_32 PF13679.6 EMR69043.1 - 0.024 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMR69043.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NST1 PF13945.6 EMR69043.1 - 0.81 9.8 2.9 0.53 10.4 0.5 1.7 2 0 0 2 2 2 0 Salt tolerance down-regulator MRI PF15325.6 EMR69043.1 - 8.2 7.6 7.4 2.2 9.4 1.5 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection MMS1_N PF10433.9 EMR69044.1 - 2.2e-147 491.7 0.0 3e-147 491.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EMR69044.1 - 6.9e-87 291.8 0.0 1.6e-82 277.4 0.0 3.7 3 1 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EMR69044.1 - 0.012 15.9 0.0 0.11 12.9 0.0 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L27A PF00828.19 EMR69045.1 - 2.5e-20 73.5 0.0 3.7e-20 72.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ketoacyl-synt PF00109.26 EMR69047.1 - 1e-60 205.5 0.1 2.2e-60 204.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EMR69047.1 - 1.2e-57 194.7 0.3 4.7e-57 192.8 0.2 2.0 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EMR69047.1 - 4.2e-55 187.1 0.0 6.5e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EMR69047.1 - 4.2e-50 171.1 0.0 7.5e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR69047.1 - 3e-37 127.2 0.6 2.3e-36 124.4 0.1 2.9 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR69047.1 - 7.7e-19 68.2 0.0 2.8e-18 66.4 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EMR69047.1 - 8e-19 68.2 0.0 3.1e-18 66.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR69047.1 - 1.1e-10 42.1 0.0 3.3e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EMR69047.1 - 4.4e-10 39.3 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 EMR69047.1 - 4.5e-10 40.1 0.0 1.5e-09 38.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR69047.1 - 5.5e-10 39.3 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR69047.1 - 3.2e-09 36.8 0.0 1e-08 35.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.6 EMR69047.1 - 3.7e-07 29.9 0.0 1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EMR69047.1 - 1.2e-06 28.8 0.1 2.9e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EMR69047.1 - 3.2e-06 26.6 0.0 6.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 EMR69047.1 - 0.00054 19.2 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent PTSIIB_sorb PF03830.15 EMR69047.1 - 0.049 13.9 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Epimerase PF01370.21 EMR69047.1 - 0.053 13.0 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PCMT PF01135.19 EMR69047.1 - 0.18 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Helicase_C_2 PF13307.6 EMR69048.1 - 5.3e-53 179.7 0.0 1.6e-52 178.1 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EMR69048.1 - 1.6e-47 161.4 0.0 2.5e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EMR69048.1 - 0.0012 18.8 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMR69048.1 - 0.0094 16.2 0.1 5.5 7.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF3847 PF12958.7 EMR69048.1 - 0.51 10.5 3.2 1.5 9.0 3.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Glyco_transf_28 PF03033.20 EMR69049.1 - 5.9e-29 100.9 0.0 1.2e-28 99.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 EMR69049.1 - 2.3e-20 72.6 0.0 6e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 GRAM domain UDPGT PF00201.18 EMR69049.1 - 0.016 14.0 0.1 0.03 13.1 0.1 1.4 1 1 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Arylesterase PF01731.20 EMR69050.1 - 0.00011 22.3 0.1 0.00022 21.4 0.1 1.5 1 0 0 1 1 1 1 Arylesterase Peptidase_S10 PF00450.22 EMR69051.1 - 2.1e-12 47.2 0.0 2.9e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Transferase PF02458.15 EMR69052.1 - 7.4e-15 54.5 0.0 5.8e-12 45.0 0.0 2.8 2 1 0 2 2 2 2 Transferase family Pkinase PF00069.25 EMR69053.1 - 4.4e-43 147.6 0.0 1.2e-39 136.3 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR69053.1 - 1e-12 47.9 0.0 2.1e-06 27.2 0.0 3.8 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 EMR69053.1 - 6.5e-06 26.3 0.2 0.001 19.0 0.2 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EMR69053.1 - 0.00014 21.3 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EMR69053.1 - 0.0054 16.1 0.1 0.13 11.6 0.0 2.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMR69053.1 - 0.01 14.7 0.0 0.039 12.7 0.0 1.9 1 1 1 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 EMR69053.1 - 0.017 14.7 0.1 0.75 9.4 0.0 2.9 2 1 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 DUF3507 PF12015.8 EMR69054.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) FAD_binding_3 PF01494.19 EMR69055.1 - 6e-22 78.4 0.4 5.3e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EMR69055.1 - 1.6e-05 23.8 0.3 0.085 11.5 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 EMR69055.1 - 2.3e-05 23.8 0.6 0.00033 20.0 0.5 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR69055.1 - 4.5e-05 23.2 0.5 0.00076 19.2 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR69055.1 - 4.7e-05 22.4 1.0 7.3e-05 21.8 0.4 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EMR69055.1 - 0.0001 21.7 0.8 0.0041 16.4 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR69055.1 - 0.00022 20.4 0.9 0.00042 19.5 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR69055.1 - 0.00032 20.9 0.1 0.00078 19.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR69055.1 - 0.0042 16.2 0.6 0.038 13.1 0.6 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 EMR69055.1 - 0.027 13.8 0.3 0.85 8.8 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 EMR69055.1 - 0.028 13.6 0.1 0.089 12.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EMR69055.1 - 0.059 13.9 1.4 0.24 12.0 0.2 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF992 PF06186.11 EMR69055.1 - 0.069 13.0 0.4 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF992) GIDA PF01134.22 EMR69055.1 - 0.21 10.7 0.6 0.28 10.2 0.1 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Cnd1_N PF12922.7 EMR69056.1 - 6.4e-61 205.0 0.1 6.4e-61 205.0 0.1 2.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EMR69056.1 - 3e-38 131.4 2.5 1.7e-34 119.2 0.9 3.5 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EMR69056.1 - 6.4e-08 32.2 3.4 0.18 12.2 0.0 6.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EMR69056.1 - 1.4e-07 31.8 2.0 0.0026 18.1 0.1 4.4 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EMR69056.1 - 0.00035 21.0 5.5 0.18 12.3 0.1 5.8 6 0 0 6 6 6 1 HEAT-like repeat Adaptin_N PF01602.20 EMR69056.1 - 0.0043 15.7 5.7 0.043 12.4 0.3 3.2 4 0 0 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 EMR69056.1 - 0.025 14.8 0.1 19 5.5 0.0 3.3 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 B2 PF11473.8 EMR69056.1 - 0.025 14.3 0.1 0.11 12.3 0.1 2.1 1 0 0 1 1 1 0 RNA binding protein B2 LTXXQ PF07813.12 EMR69056.1 - 8.2 7.2 7.7 8 7.2 0.2 4.1 3 1 0 3 3 3 0 LTXXQ motif family protein PH PF00169.29 EMR69057.1 - 5e-15 55.9 0.0 9.6e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 EMR69057.1 - 1.2e-10 41.3 0.3 9.3e-06 25.5 0.1 2.3 2 0 0 2 2 2 2 GRAM domain PH_11 PF15413.6 EMR69057.1 - 4.1e-06 27.2 0.3 0.00022 21.6 0.3 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EMR69057.1 - 6.6e-05 23.1 0.1 0.00013 22.2 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EMR69057.1 - 0.00013 22.0 0.0 0.0003 20.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 EMR69057.1 - 0.039 14.2 0.1 0.096 13.0 0.0 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 EMR69057.1 - 0.069 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Vps36_ESCRT-II PF11605.8 EMR69057.1 - 0.08 13.1 0.2 3.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 Fungal_trans PF04082.18 EMR69058.1 - 5.3e-19 68.3 0.1 7.1e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Porphobil_deam PF01379.20 EMR69059.1 - 2.8e-77 258.8 0.0 3.7e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EMR69059.1 - 6.1e-20 71.4 1.5 1.1e-19 70.6 1.5 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Hap4_Hap_bind PF10297.9 EMR69060.1 - 1.2e-08 34.8 6.9 1.2e-08 34.8 6.9 1.9 2 0 0 2 2 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EMR69060.1 - 6.3e-05 23.0 12.7 0.0011 19.1 12.7 2.3 1 1 0 1 1 1 1 bZIP transcription factor Troponin PF00992.20 EMR69060.1 - 0.00023 21.5 2.0 0.00041 20.7 2.0 1.4 1 0 0 1 1 1 1 Troponin DUF4618 PF15397.6 EMR69060.1 - 0.001 18.6 1.2 0.0015 18.0 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) HAP1_N PF04849.13 EMR69060.1 - 0.0069 15.6 5.4 0.011 15.0 5.4 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ATG16 PF08614.11 EMR69060.1 - 0.0088 16.3 6.2 0.02 15.1 6.2 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EMR69060.1 - 0.012 14.5 3.1 0.017 14.0 3.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CCDC144C PF14915.6 EMR69060.1 - 0.023 13.8 4.8 0.034 13.3 4.8 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region CLZ PF16526.5 EMR69060.1 - 0.024 15.0 4.5 0.059 13.7 4.4 1.7 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SHE3 PF17078.5 EMR69060.1 - 0.04 13.6 0.2 0.06 13.1 0.2 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Hpt PF01627.23 EMR69060.1 - 0.046 14.0 3.9 0.11 12.8 3.9 1.6 1 0 0 1 1 1 0 Hpt domain Golgin_A5 PF09787.9 EMR69060.1 - 0.061 12.8 4.9 0.1 12.1 4.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4763 PF15960.5 EMR69060.1 - 0.062 12.6 4.8 0.11 11.7 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) dsrm PF00035.26 EMR69060.1 - 0.08 13.7 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF3450 PF11932.8 EMR69060.1 - 0.084 12.2 4.9 0.13 11.5 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spectrin PF00435.21 EMR69060.1 - 0.084 13.4 3.1 1.2 9.7 3.1 2.3 2 0 0 2 2 2 0 Spectrin repeat HeLo PF14479.6 EMR69060.1 - 0.088 12.6 2.2 0.86 9.4 2.3 2.1 2 0 0 2 2 2 0 Prion-inhibition and propagation HAUS-augmin3 PF14932.6 EMR69060.1 - 0.12 12.0 6.6 0.19 11.3 6.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Bacillus_HBL PF05791.11 EMR69060.1 - 0.12 12.2 0.2 0.19 11.5 0.2 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PspB PF06667.12 EMR69060.1 - 0.15 12.1 0.5 0.41 10.7 0.2 1.8 1 1 1 2 2 2 0 Phage shock protein B Jnk-SapK_ap_N PF09744.9 EMR69060.1 - 0.17 12.1 14.3 0.18 12.1 1.0 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 EMR69060.1 - 0.23 11.5 0.6 0.43 10.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 EMR69060.1 - 0.24 10.2 4.4 0.37 9.6 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FAM184 PF15665.5 EMR69060.1 - 0.25 11.1 7.0 0.46 10.2 7.0 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HIP1_clath_bdg PF16515.5 EMR69060.1 - 0.31 11.7 5.7 0.59 10.8 5.7 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fmp27_WPPW PF10359.9 EMR69060.1 - 0.35 9.7 4.6 0.49 9.2 4.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 EMR69060.1 - 0.44 9.8 3.5 0.65 9.3 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 EMR69060.1 - 0.47 10.7 2.8 0.85 9.9 2.8 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Csm1_N PF18504.1 EMR69060.1 - 0.57 10.6 3.2 0.72 10.2 2.1 1.7 1 1 0 1 1 1 0 Csm1 N-terminal domain APG6_N PF17675.1 EMR69060.1 - 1.1 9.7 10.9 2 8.9 10.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 EMR69060.1 - 1.8 9.0 3.8 12 6.3 1.6 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2968 PF11180.8 EMR69060.1 - 2.8 7.5 8.3 5 6.7 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) bZIP_Maf PF03131.17 EMR69060.1 - 2.9 8.5 12.3 0.29 11.7 7.7 1.7 2 0 0 2 2 1 0 bZIP Maf transcription factor DivIC PF04977.15 EMR69060.1 - 3.7 7.4 5.7 2.6 7.9 3.8 1.7 1 1 1 2 2 2 0 Septum formation initiator Cluap1 PF10234.9 EMR69060.1 - 3.7 6.9 6.4 5.6 6.3 6.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 ADIP PF11559.8 EMR69060.1 - 4.2 7.4 11.7 6.9 6.7 11.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF5320 PF17253.2 EMR69060.1 - 9.1 7.4 8.9 0.85 10.7 0.6 3.1 3 0 0 3 3 2 0 Family of unknown function (DUF5320) Opi1 PF08618.10 EMR69061.1 - 2e-38 132.8 1.6 1.4e-26 93.7 0.1 2.1 1 1 1 2 2 2 2 Transcription factor Opi1 Ras PF00071.22 EMR69062.1 - 1.6e-31 109.1 0.1 2e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR69062.1 - 4.7e-24 84.9 0.1 8.3e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR69062.1 - 1.4e-06 27.9 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMR69062.1 - 0.00024 20.5 0.1 0.00032 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EMR69062.1 - 0.0018 17.2 0.3 0.18 10.6 0.0 2.2 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 EMR69062.1 - 0.37 9.9 1.8 0.49 9.5 0.1 2.0 2 1 1 3 3 3 0 G-protein alpha subunit Gtr1_RagA PF04670.12 EMR69064.1 - 4.5e-73 245.4 0.0 5.9e-73 245.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EMR69064.1 - 0.00012 21.8 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EMR69064.1 - 0.00051 19.5 0.1 0.00085 18.8 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMR69064.1 - 0.0013 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FAD_binding_4 PF01565.23 EMR69065.1 - 2.7e-14 53.1 0.3 4.3e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain tRNA-synt_1c PF00749.21 EMR69066.1 - 2.5e-99 332.1 0.0 3.5e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EMR69066.1 - 1.3e-38 132.6 0.1 2.7e-38 131.6 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HET PF06985.11 EMR69067.1 - 1.9e-07 31.6 0.8 2.2e-07 31.3 0.8 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Toxin_13 PF07822.11 EMR69067.1 - 0.0058 16.7 2.2 0.013 15.6 2.2 1.6 1 1 0 1 1 1 1 Neurotoxin B-IV-like protein Ribosomal_L1 PF00687.21 EMR69068.1 - 9e-19 68.0 0.0 1.1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF4869 PF16163.5 EMR69069.1 - 0.0037 17.0 0.2 0.0051 16.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4869) Adeno_PX PF05829.12 EMR69069.1 - 0.0087 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Adenovirus late L2 mu core protein (Protein X) FAD_binding_4 PF01565.23 EMR69070.1 - 3.7e-19 68.8 1.4 7.1e-19 67.9 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR69070.1 - 1.3e-11 44.4 0.1 2.5e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like DUF3053 PF11254.8 EMR69072.1 - 0.036 13.6 0.3 0.61 9.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) DUF4407 PF14362.6 EMR69072.1 - 0.17 11.2 1.7 0.19 11.1 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Vps51 PF08700.11 EMR69072.1 - 0.3 11.2 1.4 0.62 10.2 0.1 2.1 3 0 0 3 3 3 0 Vps51/Vps67 Med21 PF11221.8 EMR69072.1 - 0.8 10.0 4.8 2.3 8.5 4.8 1.8 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Lyase_1 PF00206.20 EMR69073.1 - 7.6e-91 304.7 0.0 9.5e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EMR69073.1 - 7.4e-23 81.1 0.0 2.5e-22 79.4 0.0 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Lipase_GDSL_2 PF13472.6 EMR69074.1 - 1.9e-11 44.7 1.3 2.6e-11 44.2 1.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR69074.1 - 2e-05 24.7 0.7 4.4e-05 23.6 0.7 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SGL PF08450.12 EMR69075.1 - 1.5e-06 28.0 0.0 1.2e-05 25.0 0.1 2.2 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region COG2 PF06148.11 EMR69076.1 - 5.7e-26 91.2 0.0 1.2e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EMR69076.1 - 5.9e-05 23.1 0.0 0.00016 21.7 0.0 1.8 1 1 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EMR69076.1 - 0.028 14.6 0.0 0.065 13.4 0.0 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Vps54_N PF10475.9 EMR69076.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Uso1_p115_C PF04871.13 EMR69076.1 - 0.95 9.8 7.0 3 8.2 6.1 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MFS_1 PF07690.16 EMR69077.1 - 1.8e-29 102.8 27.9 1.8e-29 102.8 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR69077.1 - 9.7e-10 37.9 8.0 2.2e-09 36.7 8.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EMR69077.1 - 0.0042 15.6 0.2 0.0069 14.9 0.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COX14 PF14880.6 EMR69077.1 - 6.1 6.8 4.8 4.7 7.1 0.5 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly FMN_dh PF01070.18 EMR69078.1 - 3.4e-86 289.4 0.6 1.1e-49 169.3 0.2 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 EMR69078.1 - 2.2e-05 23.6 0.2 4.3e-05 22.7 0.2 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMR69078.1 - 7.6e-05 22.3 0.3 0.00016 21.2 0.3 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EMR69078.1 - 0.00034 19.9 0.1 0.00051 19.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EMR69078.1 - 0.0017 17.7 0.2 0.23 10.6 0.1 2.3 1 1 0 2 2 2 2 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EMR69078.1 - 0.003 17.1 0.5 0.12 11.8 0.1 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein QRPTase_C PF01729.19 EMR69078.1 - 0.0097 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Exo_endo_phos PF03372.23 EMR69079.1 - 0.00065 19.3 0.0 0.00091 18.8 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GFO_IDH_MocA PF01408.22 EMR69080.1 - 8e-23 81.5 0.6 2.9e-16 60.4 0.0 3.4 2 1 1 3 3 3 3 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EMR69080.1 - 0.02 15.6 0.6 0.083 13.5 0.1 2.3 4 0 0 4 4 4 0 Homoserine dehydrogenase, NAD binding domain PNTB PF02233.16 EMR69082.1 - 4.5e-174 579.7 28.9 4.5e-174 579.7 28.9 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EMR69082.1 - 2.7e-75 252.4 0.1 8.8e-75 250.7 0.1 2.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EMR69082.1 - 1.2e-47 161.6 0.6 4.5e-47 159.8 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EMR69082.1 - 1.7e-30 105.3 3.0 1.7e-30 105.3 3.0 5.2 3 1 3 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EMR69082.1 - 0.00077 18.9 0.3 0.18 11.2 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EMR69082.1 - 0.0044 17.0 0.6 0.046 13.7 0.1 3.0 3 1 0 3 3 3 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 EMR69082.1 - 0.016 14.5 0.6 0.032 13.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR69082.1 - 0.028 14.6 0.9 0.2 11.9 0.5 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EMR69082.1 - 0.084 11.9 0.8 0.15 11.1 0.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Abhydrolase_1 PF00561.20 EMR69083.1 - 3.2e-25 89.2 0.0 7e-25 88.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR69083.1 - 4.1e-14 52.4 0.0 1.1e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR69083.1 - 4.1e-08 34.1 1.4 6e-08 33.6 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EMR69083.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Adap_comp_sub PF00928.21 EMR69084.1 - 3.2e-91 305.4 0.0 6.3e-91 304.4 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMR69084.1 - 3.6e-07 30.2 2.7 1.1e-06 28.6 2.7 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EMR69084.1 - 0.071 12.5 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain GCV_H PF01597.19 EMR69085.1 - 1.8e-34 118.3 1.6 2.2e-34 118.0 1.6 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EMR69085.1 - 0.15 11.9 1.2 0.23 11.3 0.2 1.9 2 0 0 2 2 2 0 Biotin-requiring enzyme Sugar_tr PF00083.24 EMR69086.1 - 2.8e-66 224.3 16.4 9e-43 146.8 9.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR69086.1 - 4.9e-27 94.8 32.4 2.8e-17 62.7 5.3 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 EMR69086.1 - 0.0014 17.2 3.5 0.0044 15.5 0.0 2.7 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Ni_hydr_CYTB PF01292.20 EMR69086.1 - 8.6 5.9 13.8 1.7 8.2 8.1 2.4 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 Glyco_transf_21 PF13506.6 EMR69087.1 - 9.1e-11 41.5 0.0 0.00051 19.6 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EMR69087.1 - 0.00019 21.4 0.0 0.00084 19.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMR69087.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 PI-PLC-Y PF00387.19 EMR69088.1 - 1.8e-42 144.3 0.1 2.8e-42 143.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.19 EMR69088.1 - 9.7e-30 103.1 0.1 1.5e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain E1-E2_ATPase PF00122.20 EMR69089.1 - 1e-40 139.2 2.8 4.8e-38 130.5 1.7 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMR69089.1 - 5.2e-35 120.8 4.6 5.2e-35 120.8 4.6 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMR69089.1 - 3.3e-24 86.4 0.1 4.7e-13 49.9 0.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMR69089.1 - 2.9e-15 56.1 0.0 5.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMR69089.1 - 2.3e-09 36.8 0.0 5.3e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2231 PF09990.9 EMR69089.1 - 0.00049 20.5 0.7 0.0029 18.0 0.7 2.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) DUF2157 PF09925.9 EMR69089.1 - 0.00087 19.1 1.7 0.52 10.1 0.0 3.1 3 0 0 3 3 3 2 Predicted membrane protein (DUF2157) Hydrolase_3 PF08282.12 EMR69089.1 - 0.0083 15.9 1.1 0.017 14.9 1.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMR69089.1 - 0.016 15.6 0.0 0.41 11.0 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3099 PF11298.8 EMR69089.1 - 0.097 12.8 0.4 3.8 7.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) RAMP PF04901.13 EMR69089.1 - 0.19 11.7 0.6 0.74 9.8 0.6 2.0 1 0 0 1 1 1 0 Receptor activity modifying family Ldr_toxin PF13940.6 EMR69089.1 - 0.25 11.4 2.9 8.4 6.6 0.5 2.8 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system DUF1218 PF06749.12 EMR69089.1 - 2.5 8.7 9.3 0.12 12.9 1.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) MFS_1 PF07690.16 EMR69091.1 - 1.7e-26 93.0 30.1 8.9e-25 87.3 29.8 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR69091.1 - 1.4e-07 30.3 12.8 8.1e-07 27.8 9.8 2.6 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 EMR69093.1 - 9e-19 67.6 1.5 2.7e-17 62.7 1.5 2.7 1 1 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.21 EMR69094.1 - 1.1e-47 163.2 0.0 2.2e-47 162.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR69094.1 - 2.2e-36 124.5 0.0 5.9e-36 123.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EMR69094.1 - 5.5e-30 104.6 0.3 8.3e-30 104.0 0.3 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EMR69094.1 - 8.4e-26 91.0 0.1 1.8e-25 89.9 0.1 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EMR69094.1 - 1e-16 61.5 0.0 2.7e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EMR69094.1 - 7.2e-16 59.4 0.0 2.2e-15 57.9 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EMR69094.1 - 2.7e-12 47.1 0.0 5.2e-11 43.0 0.0 2.6 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EMR69094.1 - 1.8e-11 44.2 0.8 1.4e-10 41.4 0.0 2.7 3 0 0 3 3 3 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 EMR69094.1 - 4.7e-11 42.8 0.0 1.3e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EMR69094.1 - 2.5e-10 40.5 0.0 5.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR69094.1 - 5.4e-10 39.3 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR69094.1 - 3.4e-09 37.3 0.0 1.5e-08 35.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR69094.1 - 1e-07 32.5 0.0 2.7e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.26 EMR69094.1 - 3.6e-07 30.0 0.0 6.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_16 PF10294.9 EMR69094.1 - 2.9e-05 23.9 0.0 0.0008 19.2 0.0 2.4 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_28 PF02636.17 EMR69094.1 - 0.00044 20.0 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 EMR69094.1 - 0.0012 18.5 0.0 0.0039 16.8 0.0 1.8 1 0 0 1 1 1 1 Nodulation protein S (NodS) ADH_N PF08240.12 EMR69094.1 - 0.21 11.5 0.2 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 EMR69095.1 - 7.8e-54 183.1 0.0 1e-53 182.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CP2 PF04516.15 EMR69096.1 - 2.1e-81 272.6 0.0 3e-81 272.1 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 EMR69096.1 - 0.079 11.7 0.8 0.12 11.0 0.1 1.5 2 0 0 2 2 2 0 Tektin family DUF1996 PF09362.10 EMR69098.1 - 4.1e-80 269.1 0.4 5e-80 268.8 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ECH_1 PF00378.20 EMR69099.1 - 4.4e-38 131.0 0.0 2.4e-29 102.4 0.0 3.1 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMR69099.1 - 3.8e-23 82.5 0.2 5e-19 69.0 0.0 2.4 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase RsbRD_N PF14361.6 EMR69099.1 - 0.095 13.4 0.5 0.82 10.4 0.0 2.4 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Peptidase_M6 PF05547.11 EMR69100.1 - 1.5e-08 33.5 3.4 0.00011 20.7 1.3 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 NAD_binding_9 PF13454.6 EMR69101.1 - 5.5e-08 32.9 0.0 2.7e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMR69101.1 - 6.5e-05 22.3 0.0 0.00018 20.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR69101.1 - 0.17 11.0 0.0 0.65 9.1 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lipase_GDSL_2 PF13472.6 EMR69102.1 - 2.6e-15 57.2 1.0 3.6e-15 56.8 1.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR69102.1 - 1.2e-10 41.7 0.1 1.8e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EMR69102.1 - 0.001 19.2 0.1 0.0022 18.1 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Spindle_Spc25 PF08234.12 EMR69103.1 - 3.8 7.8 4.3 45 4.3 0.1 2.9 3 0 0 3 3 3 0 Chromosome segregation protein Spc25 Zmiz1_N PF18028.1 EMR69104.1 - 0.097 13.0 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain Ribonuclease PF00545.20 EMR69106.1 - 1.5e-07 32.1 0.1 2e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 ribonuclease Peptidase_S15 PF02129.18 EMR69107.1 - 1.9e-37 129.3 0.8 7.5e-33 114.3 0.2 2.6 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EMR69107.1 - 3.2e-24 86.1 0.0 4.5e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 EMR69107.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ank_2 PF12796.7 EMR69108.1 - 2.8e-31 107.9 0.0 5.4e-11 42.9 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR69108.1 - 5.3e-20 71.5 0.1 1.9e-07 31.5 0.0 3.3 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR69108.1 - 3.7e-19 68.5 0.1 2e-07 31.2 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR69108.1 - 1.7e-13 49.4 0.1 0.0017 18.7 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EMR69108.1 - 2e-13 50.1 1.1 0.00095 19.5 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat F-box PF00646.33 EMR69108.1 - 0.0017 18.2 0.1 0.0037 17.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMR69108.1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like Dioxygenase_C PF00775.21 EMR69110.1 - 5.3e-08 32.5 0.1 9.9e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase PerC PF06069.11 EMR69110.1 - 0.039 14.2 0.7 0.08 13.2 0.3 1.7 1 1 0 1 1 1 0 PerC transcriptional activator adh_short PF00106.25 EMR69111.1 - 4.5e-23 81.7 0.0 3.6e-21 75.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69111.1 - 1.2e-11 44.6 0.0 2e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR69111.1 - 2e-06 27.5 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR69111.1 - 2.6e-06 27.5 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Antimicrobial_7 PF08102.11 EMR69111.1 - 0.24 11.7 3.1 2.7 8.3 0.0 3.6 4 0 0 4 4 4 0 Scorpion antimicrobial peptide p450 PF00067.22 EMR69112.1 - 4e-52 177.5 0.0 5e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cys_Met_Meta_PP PF01053.20 EMR69113.1 - 1.5e-120 402.3 0.0 1.1e-109 366.5 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMR69113.1 - 4.2e-09 36.1 0.0 6.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMR69113.1 - 1.9e-08 34.0 0.0 3.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EMR69113.1 - 1.5e-07 30.7 0.1 4.6e-07 29.1 0.0 1.5 1 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMR69113.1 - 4.5e-05 22.9 0.1 0.00011 21.6 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EMR69113.1 - 0.0031 16.3 0.0 0.0046 15.7 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Met_gamma_lyase PF06838.11 EMR69113.1 - 0.022 13.3 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase ADH_zinc_N PF00107.26 EMR69113.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PrpF PF04303.13 EMR69114.1 - 1.3e-95 320.5 4.4 1.6e-95 320.3 4.4 1.0 1 0 0 1 1 1 1 PrpF protein DUF3509 PF12021.8 EMR69114.1 - 0.14 11.9 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Abhydrolase_1 PF00561.20 EMR69115.1 - 2.7e-21 76.4 0.0 2e-11 44.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DSBA PF01323.20 EMR69116.1 - 0.00039 20.3 0.0 0.0041 16.9 0.0 1.9 2 0 0 2 2 2 1 DSBA-like thioredoxin domain F_bP_aldolase PF01116.20 EMR69117.1 - 1.5e-53 182.1 0.0 1.6e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Glyco_hydro_61 PF03443.14 EMR69119.1 - 1.5e-05 25.1 0.0 2.8e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 EMR69119.1 - 0.015 16.0 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading CN_hydrolase PF00795.22 EMR69120.1 - 2.1e-57 194.4 0.0 2.4e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_2 PF00891.18 EMR69121.1 - 2.9e-21 75.7 0.0 4.7e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EMR69121.1 - 0.005 16.8 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain DUF1917 PF08939.10 EMR69122.1 - 2.8e-83 279.8 0.0 3.4e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Acetyltransf_1 PF00583.25 EMR69123.1 - 3.4e-18 66.0 0.0 5.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR69123.1 - 7.3e-10 38.9 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR69123.1 - 1.5e-09 37.7 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EMR69123.1 - 2e-09 37.8 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMR69123.1 - 2.1e-06 27.5 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMR69123.1 - 2.9e-06 28.0 0.0 4.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR69123.1 - 0.00021 21.4 0.1 0.00043 20.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR69123.1 - 0.0056 16.8 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Pkinase PF00069.25 EMR69124.1 - 3.3e-68 229.9 0.0 4.1e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR69124.1 - 7.7e-32 110.6 0.0 1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMR69124.1 - 0.00053 19.4 0.3 0.00088 18.7 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMR69124.1 - 0.0011 17.9 0.2 0.0018 17.3 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EMR69124.1 - 0.009 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Gag_p6 PF08705.11 EMR69124.1 - 0.021 15.1 0.1 0.042 14.1 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 APH PF01636.23 EMR69124.1 - 0.025 14.5 0.2 0.057 13.3 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family S_100 PF01023.19 EMR69124.1 - 0.03 14.0 0.2 0.091 12.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Seadorna_VP7 PF07387.11 EMR69124.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Xpo1 PF08389.12 EMR69125.1 - 3e-07 30.6 0.1 7.2e-06 26.1 0.0 2.8 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EMR69125.1 - 2.9e-05 23.9 0.0 0.00017 21.5 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec23_trunk PF04811.15 EMR69126.1 - 1.6e-70 237.5 0.0 2.7e-70 236.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EMR69126.1 - 1.4e-22 79.5 0.1 4.7e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EMR69126.1 - 2.6e-18 66.5 0.1 5.2e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EMR69126.1 - 2.2e-16 59.6 5.0 3.9e-16 58.8 5.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EMR69126.1 - 4.7e-10 39.2 0.0 1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EMR69126.1 - 0.043 13.2 0.2 0.1 12.0 0.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 EMR69126.1 - 0.056 14.1 0.1 1.8 9.2 0.0 2.9 3 0 0 3 3 3 0 von Willebrand factor type A domain AftA_N PF12250.8 EMR69127.1 - 0.013 14.2 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal Consortin_C PF15281.6 EMR69127.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Consortin C-terminus LCAT PF02450.15 EMR69128.1 - 7.1e-102 341.5 0.0 8.8e-102 341.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 EMR69128.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) DUF1749 PF08538.10 EMR69128.1 - 0.085 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) RNA_helicase PF00910.22 EMR69129.1 - 0.0045 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DAP3 PF10236.9 EMR69129.1 - 0.0078 15.4 0.1 0.054 12.7 0.1 2.0 1 1 1 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 EMR69129.1 - 0.0091 15.9 0.1 0.028 14.3 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EMR69129.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EMR69129.1 - 0.082 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR69129.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MFS_1 PF07690.16 EMR69130.1 - 1.9e-40 138.9 44.5 7.9e-37 127.0 33.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMR69130.1 - 0.0019 16.6 0.8 0.0019 16.6 0.8 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Hemerythrin PF01814.23 EMR69132.1 - 4.6e-09 37.0 0.1 6.2e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Fer4 PF00037.27 EMR69133.1 - 1.6e-13 49.9 16.5 6.3e-08 32.1 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EMR69133.1 - 8.1e-13 48.8 10.2 1.6e-12 47.8 10.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EMR69133.1 - 1.5e-10 41.8 7.1 6.9e-05 23.7 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EMR69133.1 - 3.2e-09 36.8 31.7 7.4e-06 26.0 12.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMR69133.1 - 1.4e-08 34.7 21.0 2.6e-06 27.4 12.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMR69133.1 - 2.8e-08 33.8 9.4 5.4e-08 32.9 9.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMR69133.1 - 5.3e-07 30.0 19.2 0.00015 22.2 11.2 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EMR69133.1 - 1.3e-06 28.2 17.1 0.00041 20.3 5.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EMR69133.1 - 5.1e-06 26.3 11.8 0.01 15.9 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EMR69133.1 - 9.7e-06 25.7 11.4 0.00031 21.0 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EMR69133.1 - 0.0004 20.9 12.1 0.077 13.5 13.2 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EMR69133.1 - 0.005 17.0 5.3 0.81 10.0 0.4 2.4 1 1 1 2 2 2 2 c-SKI Smad4 binding domain ETF_QO PF05187.13 EMR69133.1 - 0.04 14.0 5.2 0.21 11.7 0.4 2.4 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 EMR69133.1 - 0.062 13.5 8.8 1.2 9.3 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EMR69133.1 - 0.26 12.3 15.5 0.44 11.6 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 EMR69133.1 - 1.7 9.2 19.9 0.77 10.4 4.3 2.9 3 1 1 4 4 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 EMR69133.1 - 5 8.0 14.9 4.1 8.3 2.0 2.6 2 1 1 3 3 2 0 4Fe-4S dicluster domain Sugar_tr PF00083.24 EMR69135.1 - 1.9e-95 320.4 18.7 2.3e-95 320.1 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR69135.1 - 3.7e-22 78.7 21.9 3.7e-22 78.7 21.9 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily YscJ_FliF PF01514.17 EMR69135.1 - 0.16 11.6 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family Glyco_hydro_3_C PF01915.22 EMR69136.1 - 1.6e-53 181.7 0.0 2.3e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR69136.1 - 8.5e-35 120.6 0.0 1.3e-34 120.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR69136.1 - 0.0012 18.9 0.6 0.044 13.9 0.6 2.5 1 1 0 1 1 1 1 Fibronectin type III-like domain Epimerase PF01370.21 EMR69137.1 - 1.4e-05 24.7 0.1 4.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR69137.1 - 8e-05 21.8 0.0 0.00012 21.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMR69137.1 - 8.7e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR69137.1 - 0.00018 21.2 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMR69137.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EMR69137.1 - 0.15 11.2 0.0 5.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein adh_short PF00106.25 EMR69137.1 - 0.3 10.5 1.0 0.38 10.2 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase HET PF06985.11 EMR69138.1 - 3.5e-26 92.3 5.8 3.5e-26 92.3 5.8 3.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Mpp10 PF04006.12 EMR69138.1 - 0.00029 19.4 13.3 0.00029 19.4 13.3 1.7 2 0 0 2 2 2 1 Mpp10 protein Transketolase_C PF02780.20 EMR69138.1 - 0.097 12.6 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Transketolase, C-terminal domain IML1 PF12257.8 EMR69138.1 - 0.13 11.4 0.5 5.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Vacuolar membrane-associated protein Iml1 DUF4628 PF15429.6 EMR69138.1 - 0.88 9.2 4.8 1.6 8.3 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) CobT PF06213.12 EMR69138.1 - 1.6 8.0 28.5 0.68 9.3 22.4 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT HSP90 PF00183.18 EMR69138.1 - 4.7 6.0 12.1 11 4.8 12.1 1.6 1 0 0 1 1 1 0 Hsp90 protein NPR3 PF03666.13 EMR69138.1 - 7.2 5.3 10.6 17 4.0 8.5 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RPA43_OB PF17875.1 EMR69138.1 - 9 6.9 9.1 12 6.5 6.1 2.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I ABM PF03992.16 EMR69139.1 - 1.4e-08 34.7 0.3 0.0011 19.1 0.0 2.7 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.13 EMR69139.1 - 0.048 13.9 0.1 1.8 8.8 0.1 2.4 2 0 0 2 2 2 0 NIPSNAP Protoglobin PF11563.8 EMR69140.1 - 1.5e-58 197.2 0.1 1.8e-58 197.0 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Glyco_hydro_61 PF03443.14 EMR69141.1 - 2.6e-44 151.6 0.0 3.1e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PP-binding PF00550.25 EMR69142.1 - 2.1e-12 47.2 0.1 2.7e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EMR69142.1 - 4.7e-05 23.5 0.1 6.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Sugar_tr PF00083.24 EMR69143.1 - 2.9e-71 240.7 17.9 8.3e-69 232.6 8.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Beta-lactamase PF00144.24 EMR69143.1 - 1e-25 90.7 0.0 1.7e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 EMR69143.1 - 2.7e-25 89.1 21.1 3.9e-25 88.5 21.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR69143.1 - 2.2e-07 29.7 1.7 3.6e-07 29.0 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.25 EMR69144.1 - 0.0064 15.9 0.0 0.79 9.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR69144.1 - 0.0083 15.4 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Transp_cyt_pur PF02133.15 EMR69145.1 - 1.1e-36 126.6 28.7 1.7e-36 126.0 28.7 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.25 EMR69146.1 - 5e-06 26.1 0.0 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR69146.1 - 5.4e-05 23.2 0.0 8.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR69146.1 - 0.0038 16.7 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 EMR69146.1 - 0.011 15.2 0.0 0.024 14.2 0.0 1.4 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 EMR69146.1 - 0.026 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.6 EMR69146.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Nitroreductase PF00881.24 EMR69147.1 - 2.3e-12 47.3 0.1 3e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family LRS4 PF10422.9 EMR69147.1 - 0.19 11.3 0.1 0.24 10.9 0.1 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 FAD_binding_4 PF01565.23 EMR69148.1 - 2e-25 89.1 0.1 3.9e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR69148.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Aldo_ket_red PF00248.21 EMR69149.1 - 1.4e-72 244.4 0.0 1.6e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WSC PF01822.19 EMR69150.1 - 1.8e-14 53.7 9.6 3.7e-14 52.7 9.6 1.5 1 0 0 1 1 1 1 WSC domain FAD_binding_4 PF01565.23 EMR69151.1 - 2e-29 102.1 0.8 3.4e-29 101.3 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR69151.1 - 0.087 12.9 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like GRIM-19 PF06212.12 EMR69152.1 - 3.9e-23 81.8 0.1 8.4e-23 80.8 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein p450 PF00067.22 EMR69153.1 - 1.9e-08 33.5 0.0 9.5e-05 21.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 PP2C_2 PF13672.6 EMR69154.1 - 0.13 11.9 0.2 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein phosphatase 2C p450 PF00067.22 EMR69155.1 - 1.3e-61 208.8 0.0 1.7e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 EMR69156.1 - 1e-07 32.5 8.2 0.18 12.7 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat MFS_1 PF07690.16 EMR69157.1 - 1.4e-41 142.6 36.6 4.2e-41 141.0 19.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NIF PF03031.18 EMR69158.1 - 4.7e-27 94.7 0.0 1.2e-26 93.3 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Biotin_lipoyl PF00364.22 EMR69158.1 - 4.6e-06 26.4 0.1 0.016 15.0 0.1 3.0 3 0 0 3 3 3 2 Biotin-requiring enzyme PTCB-BRCT PF12738.7 EMR69158.1 - 0.00026 20.9 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EMR69158.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.6 EMR69158.1 - 0.079 12.8 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like RTT107_BRCT_5 PF16770.5 EMR69158.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain adh_short_C2 PF13561.6 EMR69159.1 - 3.1e-60 203.6 0.8 4e-60 203.3 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR69159.1 - 1.3e-46 158.5 1.4 1.7e-46 158.1 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR69159.1 - 4.3e-07 30.0 1.0 1.1e-06 28.7 0.9 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR69159.1 - 0.0023 17.4 0.3 0.0038 16.7 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EMR69159.1 - 0.013 15.4 0.7 0.019 14.8 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EMR69159.1 - 0.058 14.0 0.1 0.13 12.9 0.1 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Vps36_ESCRT-II PF11605.8 EMR69160.1 - 0.087 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Methyltransf_9 PF08003.11 EMR69160.1 - 0.089 11.7 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Aldo_ket_red PF00248.21 EMR69161.1 - 8.8e-63 212.2 0.0 9.9e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.6 EMR69161.1 - 0.061 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 FliG middle domain Glyco_hydro_61 PF03443.14 EMR69162.1 - 1.5e-57 194.9 0.1 1.8e-57 194.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acyl-CoA_dh_2 PF08028.11 EMR69163.1 - 1.7e-12 47.8 3.0 4.5e-12 46.4 3.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pro_CA PF00484.19 EMR69163.1 - 2.3e-10 41.0 1.1 5.7e-10 39.7 0.1 2.2 2 1 1 3 3 3 1 Carbonic anhydrase Acyl-CoA_dh_N PF02771.16 EMR69163.1 - 6.8e-10 39.6 0.0 1.7e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EMR69163.1 - 1.2e-05 25.6 1.3 3.1e-05 24.2 1.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMR69163.1 - 0.00076 19.6 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Pim PF16765.5 EMR69163.1 - 0.00088 19.4 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Pesticin immunity protein adh_short PF00106.25 EMR69164.1 - 1.4e-06 27.9 0.1 1.8e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69164.1 - 5.5e-05 22.8 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.25 EMR69165.1 - 1.3e-22 80.4 0.0 5e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR69165.1 - 3.7e-08 33.0 0.0 3e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EMR69165.1 - 0.073 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EMR69165.1 - 0.15 11.0 0.1 0.27 10.2 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase COesterase PF00135.28 EMR69166.1 - 8.4e-68 229.5 0.0 1.1e-67 229.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR69166.1 - 1.6e-06 28.1 0.3 7.3e-06 26.0 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR69166.1 - 0.029 13.8 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_3_C PF01915.22 EMR69168.1 - 2.5e-49 168.0 0.1 3.7e-49 167.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR69168.1 - 4.9e-33 114.8 0.0 1.6e-32 113.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR69168.1 - 7.9e-25 86.8 0.0 1.5e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3292 PF11696.8 EMR69169.1 - 1.9e-274 912.1 0.0 3.3e-273 908.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) MtrB PF05440.12 EMR69169.1 - 0.0098 16.3 0.0 0.9 10.0 0.0 2.9 3 0 0 3 3 3 1 Tetrahydromethanopterin S-methyltransferase subunit B Methyltransf_2 PF00891.18 EMR69170.1 - 0.0044 16.3 0.0 0.0055 16.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain HET PF06985.11 EMR69171.1 - 8.2e-09 36.0 0.0 1.2e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_N PF08240.12 EMR69173.1 - 3.9e-19 68.6 4.0 6.4e-19 67.9 4.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR69173.1 - 1.7e-10 41.0 0.0 3.5e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMR69173.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.9 EMR69173.1 - 0.021 14.9 0.6 0.055 13.5 0.2 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region AlaDh_PNT_C PF01262.21 EMR69173.1 - 0.056 12.7 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PPR_2 PF13041.6 EMR69175.1 - 0.0032 17.6 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family DUF4570 PF15134.6 EMR69175.1 - 0.28 11.2 2.6 2.6 8.1 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Ferlin_C PF16165.5 EMR69175.1 - 4 7.4 4.5 6.5 6.7 4.5 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Glyco_hydro_18 PF00704.28 EMR69176.1 - 3.1e-45 155.3 0.5 4.5e-45 154.7 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EMR69176.1 - 2.1e-16 59.7 0.0 5.8e-05 23.1 0.1 3.5 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.19 EMR69176.1 - 0.00059 20.3 7.1 0.00059 20.3 7.1 4.5 4 0 0 4 4 4 1 Chitin recognition protein Melibiase PF02065.18 EMR69177.1 - 1.3e-150 501.2 0.0 1.6e-150 500.9 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 EMR69177.1 - 1.6e-82 276.9 0.0 2.2e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 EMR69177.1 - 7.8e-21 74.4 0.0 1.5e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 EMR69177.1 - 1.2e-05 24.5 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GFO_IDH_MocA PF01408.22 EMR69178.1 - 4.3e-22 79.2 0.1 9.4e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMR69178.1 - 3.2e-07 30.3 0.1 6.3e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 EMR69178.1 - 0.013 15.9 0.0 0.12 12.7 0.0 2.5 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMR69178.1 - 0.013 16.0 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding PMI_typeI PF01238.21 EMR69179.1 - 1.2e-71 241.9 0.0 7.7e-71 239.2 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I SesA PF17107.5 EMR69179.1 - 2.5e-08 34.1 1.8 6.8e-08 32.7 0.6 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 EMR69179.1 - 6.6e-05 22.4 0.2 0.00012 21.5 0.2 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Cupin_2 PF07883.11 EMR69179.1 - 0.0014 18.3 0.1 0.96 9.2 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Peptidase_S74 PF13884.6 EMR69179.1 - 0.0057 17.0 0.3 0.043 14.1 0.0 2.3 2 0 0 2 2 2 1 Chaperone of endosialidase AraC_binding PF02311.19 EMR69179.1 - 0.021 14.7 0.2 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 AraC-like ligand binding domain AAA PF00004.29 EMR69181.1 - 9e-16 58.5 0.0 1.6e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EMR69181.1 - 8.9e-11 41.8 0.1 2.1e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 EMR69181.1 - 6.1e-10 39.7 0.0 9.1e-09 35.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMR69181.1 - 2.4e-08 34.3 0.0 5.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 EMR69181.1 - 2.7e-08 33.7 0.0 5.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 EMR69181.1 - 0.006 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EMR69181.1 - 0.012 15.6 0.0 0.25 11.2 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EMR69181.1 - 0.013 16.1 0.0 0.032 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EMR69181.1 - 0.024 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EMR69181.1 - 0.033 14.1 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 EMR69181.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR69181.1 - 0.057 13.8 0.0 0.19 12.1 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 EMR69181.1 - 0.091 13.0 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 EMR69181.1 - 0.17 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EMR69182.1 - 2e-12 47.4 6.0 0.12 13.3 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR69182.1 - 0.0087 16.3 0.1 1.8 8.9 0.0 3.5 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TMF_TATA_bd PF12325.8 EMR69183.1 - 5.7e-42 142.6 10.9 5.7e-42 142.6 10.9 6.8 3 2 3 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EMR69183.1 - 7.1e-17 61.2 10.8 7.1e-17 61.2 10.8 8.7 6 3 3 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EMR69183.1 - 0.0055 17.0 4.8 0.0055 17.0 4.8 6.1 3 1 3 6 6 6 3 Autophagy protein 16 (ATG16) PilO PF04350.13 EMR69183.1 - 0.035 14.3 0.7 0.035 14.3 0.7 5.7 3 1 2 6 6 6 0 Pilus assembly protein, PilO HSBP1 PF06825.12 EMR69183.1 - 0.042 13.7 1.0 7.1 6.6 0.0 4.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Rh5 PF18515.1 EMR69183.1 - 0.54 9.5 4.2 0.22 10.8 0.4 2.2 3 0 0 3 3 3 0 Rh5 coiled-coil domain Holin_BhlA PF10960.8 EMR69183.1 - 2.7 8.0 9.6 0.81 9.7 2.0 3.3 2 0 0 2 2 2 0 BhlA holin family DUF812 PF05667.11 EMR69183.1 - 9.2 5.0 74.0 0.094 11.6 6.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Prefoldin_2 PF01920.20 EMR69184.1 - 2.6e-11 43.4 2.4 5.2e-11 42.4 2.2 1.6 1 1 0 1 1 1 1 Prefoldin subunit SKA2 PF16740.5 EMR69184.1 - 0.011 15.5 2.5 0.089 12.6 0.0 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 TMF_TATA_bd PF12325.8 EMR69184.1 - 0.026 14.7 4.2 1 9.6 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding T6PP_N PF18572.1 EMR69184.1 - 0.027 14.3 2.1 0.052 13.4 2.1 1.5 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain LRR_6 PF13516.6 EMR69185.1 - 1.1e-08 34.5 1.4 0.013 15.5 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 EMR69185.1 - 4.2e-06 27.0 15.6 0.015 15.7 0.0 5.9 6 1 0 7 7 7 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMR69185.1 - 0.00071 19.8 0.7 14 6.7 0.1 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EMR69185.1 - 0.0057 16.4 12.7 8.3 6.3 0.2 5.3 4 1 0 4 4 4 2 Leucine rich repeat CR6_interact PF10147.9 EMR69185.1 - 0.03 14.1 2.6 0.046 13.4 2.6 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DARPP-32 PF05395.12 EMR69185.1 - 2.6 8.3 11.0 5.6 7.2 11.0 1.6 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Dynamin_M PF01031.20 EMR69187.1 - 2.3e-111 371.6 0.0 4.6e-111 370.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EMR69187.1 - 1.6e-55 187.7 0.4 4.9e-55 186.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EMR69187.1 - 8.2e-31 106.0 2.4 8.2e-31 106.0 2.4 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EMR69187.1 - 5.1e-05 23.3 0.2 0.00025 21.1 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EMR69187.1 - 0.2 11.9 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase UAA PF08449.11 EMR69188.1 - 1.3e-50 172.3 1.5 1.6e-50 172.0 1.5 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EMR69188.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter TssN PF17555.2 EMR69188.1 - 0.062 12.7 4.9 0.019 14.4 2.1 1.4 2 0 0 2 2 2 0 Type VI secretion system, TssN 7TMR-DISM_7TM PF07695.11 EMR69188.1 - 0.094 12.6 8.3 0.17 11.7 8.1 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling EamA PF00892.20 EMR69188.1 - 0.2 11.8 8.9 2.1 8.5 1.9 2.3 2 0 0 2 2 2 0 EamA-like transporter family Ost5 PF05251.12 EMR69188.1 - 0.63 10.3 0.1 0.63 10.3 0.1 2.5 2 1 0 2 2 2 0 Oligosaccharyltransferase subunit 5 A_deaminase PF00962.22 EMR69189.1 - 2.4e-125 418.2 0.2 3.2e-125 417.8 0.2 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Spc7 PF08317.11 EMR69191.1 - 1.9e-12 46.7 149.6 5.6e-05 22.2 26.6 5.7 1 1 4 5 5 5 4 Spc7 kinetochore protein GAS PF13851.6 EMR69191.1 - 5.2e-06 26.0 146.0 0.0025 17.2 21.3 6.7 1 1 6 7 7 7 6 Growth-arrest specific micro-tubule binding FPP PF05911.11 EMR69191.1 - 7e-05 21.2 42.9 7e-05 21.2 42.9 4.1 1 1 2 4 4 3 1 Filament-like plant protein, long coiled-coil TolA_bind_tri PF16331.5 EMR69191.1 - 0.00011 22.2 4.5 0.00011 22.2 4.5 9.2 3 1 4 8 8 7 1 TolA binding protein trimerisation DUF812 PF05667.11 EMR69191.1 - 0.00026 20.0 141.0 0.023 13.6 37.2 4.6 1 1 4 5 5 5 2 Protein of unknown function (DUF812) CENP-H PF05837.12 EMR69191.1 - 0.00049 20.5 13.6 0.00049 20.5 13.6 8.4 1 1 6 7 7 6 1 Centromere protein H (CENP-H) Fib_alpha PF08702.10 EMR69191.1 - 0.0015 18.8 83.7 0.038 14.2 7.5 6.9 1 1 4 6 6 6 3 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EMR69191.1 - 0.0022 18.0 23.6 0.0022 18.0 23.6 6.8 1 1 6 7 7 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EMR69191.1 - 0.0036 17.3 83.0 0.092 12.8 10.7 7.6 1 1 7 8 8 8 5 Protein of unknown function (DUF1664) SlyX PF04102.12 EMR69191.1 - 0.0082 16.7 6.3 0.0082 16.7 6.3 10.7 1 1 8 9 9 6 2 SlyX DUF3584 PF12128.8 EMR69191.1 - 0.012 13.2 140.1 0.093 10.2 54.5 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) BRE1 PF08647.11 EMR69191.1 - 0.012 15.6 22.0 0.012 15.6 22.0 9.3 1 1 8 9 9 5 0 BRE1 E3 ubiquitin ligase Laminin_II PF06009.12 EMR69191.1 - 0.014 15.4 14.7 0.014 15.4 14.7 7.5 1 1 8 9 9 8 0 Laminin Domain II Rootletin PF15035.6 EMR69191.1 - 0.017 15.1 8.7 0.017 15.1 8.7 5.9 1 1 4 6 6 5 0 Ciliary rootlet component, centrosome cohesion Filament PF00038.21 EMR69191.1 - 0.022 14.4 124.5 0.92 9.0 11.6 5.6 1 1 4 5 5 5 0 Intermediate filament protein DUF4201 PF13870.6 EMR69191.1 - 0.033 13.9 121.5 0.032 14.0 32.4 7.4 1 1 6 7 7 7 0 Domain of unknown function (DUF4201) Tup_N PF08581.10 EMR69191.1 - 0.1 12.9 99.4 0.36 11.2 4.3 10.1 2 2 9 11 11 11 0 Tup N-terminal Rab5-bind PF09311.11 EMR69191.1 - 0.1 12.0 120.3 0.056 12.8 22.6 6.3 1 1 4 5 5 5 0 Rabaptin-like protein Fez1 PF06818.15 EMR69191.1 - 0.15 12.5 136.4 0.22 12.0 28.4 5.5 1 1 3 4 4 3 0 Fez1 DUF5082 PF16888.5 EMR69191.1 - 0.52 10.6 121.8 0.15 12.4 13.0 9.2 1 1 8 9 9 9 0 Domain of unknown function (DUF5082) IFT57 PF10498.9 EMR69191.1 - 0.57 9.1 108.5 0.14 11.1 35.1 6.0 1 1 6 7 7 7 0 Intra-flagellar transport protein 57 HMMR_N PF15905.5 EMR69191.1 - 0.6 9.5 148.6 0.048 13.1 33.5 4.2 2 2 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 EMR69191.1 - 0.78 9.9 157.3 0.53 10.5 16.3 6.0 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 EMR69191.1 - 1.9 8.1 146.6 0.037 13.7 25.7 7.1 1 1 4 6 6 6 0 Ciliary protein causing Leber congenital amaurosis disease CEP63 PF17045.5 EMR69191.1 - 2.3 8.1 120.2 0.56 10.1 23.8 4.4 1 1 1 3 3 3 0 Centrosomal protein of 63 kDa MscS_porin PF12795.7 EMR69191.1 - 2.6 7.6 146.1 1.8 8.1 16.8 5.6 1 1 4 5 5 3 0 Mechanosensitive ion channel porin domain FliJ PF02050.16 EMR69191.1 - 2.8 8.2 119.3 0.026 14.7 14.4 7.7 1 1 5 7 7 7 0 Flagellar FliJ protein NPV_P10 PF05531.12 EMR69191.1 - 5.3 7.6 63.4 0.78 10.3 2.0 10.2 2 2 8 10 10 9 0 Nucleopolyhedrovirus P10 protein SH3_1 PF00018.28 EMR69192.1 - 2.2e-36 123.2 6.7 2.7e-14 52.5 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EMR69192.1 - 2.3e-35 120.2 6.9 8.3e-12 44.8 0.1 3.9 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 EMR69192.1 - 3.5e-35 119.6 0.1 6.2e-35 118.8 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 EMR69192.1 - 2.9e-26 90.9 0.0 2.2e-08 33.7 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 EMR69192.1 - 1.6e-05 24.8 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 EMR69192.1 - 0.00011 22.3 3.7 0.00062 20.0 0.8 2.9 3 0 0 3 3 3 1 Bacterial SH3 domain SH3_10 PF17902.1 EMR69192.1 - 0.00025 21.0 0.1 0.034 14.2 0.0 3.3 3 0 0 3 3 3 1 SH3 domain DUF1720 PF08226.11 EMR69192.1 - 0.014 15.8 28.8 0.014 15.8 28.8 6.2 1 1 4 5 5 5 0 Domain of unknown function (DUF1720) DUF4192 PF13830.6 EMR69192.1 - 0.019 15.0 1.1 0.036 14.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Mito_carr PF00153.27 EMR69193.1 - 4.1e-53 177.3 5.9 1.7e-19 69.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prefoldin PF02996.17 EMR69194.1 - 1.3e-16 60.6 0.0 2.2e-16 59.9 0.0 1.3 1 1 0 1 1 1 1 Prefoldin subunit GIT_CC PF16559.5 EMR69194.1 - 0.0086 15.9 1.7 0.03 14.2 1.9 1.7 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor Mst1_SARAH PF11629.8 EMR69194.1 - 0.092 12.8 1.6 2.6 8.2 0.2 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 TRAM_LAG1_CLN8 PF03798.16 EMR69195.1 - 8.1e-51 172.6 14.8 1.2e-50 172.0 14.8 1.3 1 0 0 1 1 1 1 TLC domain Phage_F PF02305.17 EMR69195.1 - 0.081 11.7 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Capsid protein (F protein) SecD_SecF PF02355.16 EMR69195.1 - 1.1 8.6 4.5 20 4.5 0.6 3.1 3 0 0 3 3 3 0 Protein export membrane protein WD40 PF00400.32 EMR69196.1 - 1.6e-44 149.0 17.5 3.1e-09 37.3 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR69196.1 - 5.2e-05 23.5 0.3 4.6 7.6 0.0 5.1 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR69196.1 - 0.0025 16.5 2.4 2.5 6.6 0.0 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EMR69196.1 - 0.098 12.0 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain Ank_2 PF12796.7 EMR69197.1 - 1.1e-32 112.4 1.2 6.7e-14 52.2 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR69197.1 - 1.4e-31 108.5 8.1 4.9e-08 33.4 0.2 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR69197.1 - 2.4e-30 104.2 5.9 6.3e-11 42.3 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR69197.1 - 5.7e-25 84.7 0.1 0.0027 18.1 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EMR69197.1 - 9.9e-17 60.6 0.9 0.0016 18.8 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat HhH-GPD PF00730.25 EMR69198.1 - 4.4e-06 27.1 0.1 1.1e-05 25.9 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein SEN1_N PF12726.7 EMR69199.1 - 9.8e-172 573.0 15.5 2.4e-129 432.8 9.3 2.1 1 1 1 2 2 2 2 SEN1 N terminal AAA_11 PF13086.6 EMR69199.1 - 2.8e-30 106.0 0.1 2.8e-30 106.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMR69199.1 - 1.6e-06 28.0 0.7 3.4e-06 26.9 0.7 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR69199.1 - 2.6e-06 27.9 0.9 1.1e-05 25.8 0.9 2.0 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EMR69199.1 - 0.0082 15.7 0.2 0.032 13.7 0.2 2.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EMR69199.1 - 0.31 11.4 1.7 3.6 7.9 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain GST_N PF02798.20 EMR69200.1 - 0.00011 22.5 0.1 0.00041 20.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMR69200.1 - 0.00013 22.2 0.0 0.00034 20.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR69200.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR69200.1 - 0.039 14.4 0.3 0.18 12.2 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain Plant_NMP1 PF06694.11 EMR69200.1 - 0.046 12.8 0.0 0.06 12.4 0.0 1.3 1 1 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) GST_C PF00043.25 EMR69200.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ATP-synt_C PF00137.21 EMR69201.1 - 1.5e-27 95.7 28.0 8.4e-16 58.1 11.8 2.4 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 EMR69201.1 - 0.029 13.7 1.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 adh_short PF00106.25 EMR69202.1 - 1.1e-36 126.1 2.0 1.7e-36 125.5 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69202.1 - 3.9e-31 108.4 1.5 5.5e-31 107.9 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR69202.1 - 7.9e-13 48.7 1.4 1.3e-12 47.9 1.4 1.3 1 0 0 1 1 1 1 KR domain Abhydrolase_6 PF12697.7 EMR69202.1 - 2.4e-12 47.9 4.4 2.4e-12 47.9 4.4 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR69202.1 - 8.5e-07 28.5 0.0 1.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1776 PF08643.10 EMR69202.1 - 0.00028 20.4 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EMR69202.1 - 0.0018 18.2 0.6 0.0043 17.0 0.3 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMR69202.1 - 0.025 14.1 0.2 0.037 13.6 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Ndr PF03096.14 EMR69202.1 - 0.077 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family DFP PF04127.15 EMR69202.1 - 0.1 12.4 0.8 0.19 11.6 0.8 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PfkB PF00294.24 EMR69202.1 - 0.13 11.6 0.3 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Chlorophyllase2 PF12740.7 EMR69202.1 - 0.14 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Epimerase PF01370.21 EMR69202.1 - 0.15 11.5 0.3 0.78 9.1 0.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_S9 PF00326.21 EMR69202.1 - 0.15 11.5 0.1 7.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family tRNA_bind PF01588.20 EMR69203.1 - 1.3e-21 76.5 0.1 4e-21 74.9 0.1 1.9 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 EMR69203.1 - 0.00011 22.3 2.0 0.00015 21.9 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR69203.1 - 0.00047 20.1 0.0 0.00097 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GHMP_kinases_C PF08544.13 EMR69203.1 - 0.08 13.3 0.3 0.2 12.0 0.3 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal GST_C_3 PF14497.6 EMR69203.1 - 0.13 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Rotamase_2 PF13145.6 EMR69203.1 - 1.3 9.9 16.7 5.2 7.9 6.1 3.1 2 1 1 3 3 3 0 PPIC-type PPIASE domain DHHA2 PF02833.14 EMR69204.1 - 3.7e-36 124.4 0.0 5.3e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EMR69204.1 - 5.5e-09 36.2 0.0 9.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 DHH family RsfS PF02410.15 EMR69205.1 - 4.4e-10 39.9 0.0 1.5e-09 38.2 0.0 2.0 2 1 0 2 2 2 1 Ribosomal silencing factor during starvation PPR PF01535.20 EMR69205.1 - 0.22 11.9 0.2 23 5.5 0.0 3.6 4 0 0 4 4 4 0 PPR repeat RNA_pol PF00940.19 EMR69206.1 - 3.5e-187 622.3 0.0 5.3e-187 621.7 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EMR69206.1 - 2.4e-104 349.4 2.2 4e-104 348.6 2.2 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal SPATA3 PF15662.5 EMR69206.1 - 0.0018 18.9 5.7 0.0041 17.8 5.7 1.5 1 0 0 1 1 1 1 Spermatogenesis-associated protein 3 family adh_short PF00106.25 EMR69208.1 - 2.3e-17 63.1 0.0 3e-14 52.9 0.0 2.3 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69208.1 - 2.1e-10 40.6 0.0 2.1e-08 34.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR69208.1 - 0.00042 20.3 0.0 0.0006 19.8 0.0 1.2 1 0 0 1 1 1 1 KR domain UQ_con PF00179.26 EMR69210.1 - 1.3e-19 70.2 0.1 1.8e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 EMR69211.1 - 4.5e-40 138.1 1.1 5.4e-40 137.9 1.1 1.1 1 0 0 1 1 1 1 Surface antigen peroxidase PF00141.23 EMR69212.1 - 3.9e-21 75.8 1.7 8.1e-21 74.8 1.7 1.5 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 EMR69212.1 - 0.023 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK Big_6 PF17936.1 EMR69212.1 - 0.069 13.4 1.1 6.5 7.1 0.0 3.6 3 0 0 3 3 3 0 Bacterial Ig domain CorA PF01544.18 EMR69213.1 - 3.3e-07 29.9 0.2 8.6e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Rx_N PF18052.1 EMR69213.1 - 0.011 15.9 0.7 4.2 7.7 0.0 2.8 1 1 1 2 2 2 0 Rx N-terminal domain Val_tRNA-synt_C PF10458.9 EMR69213.1 - 0.015 15.6 0.1 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm AAA PF00004.29 EMR69214.1 - 4.9e-27 95.0 0.0 7.6e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 EMR69214.1 - 2.4e-06 27.6 0.0 5.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.6 EMR69214.1 - 1.2e-05 25.8 0.0 5e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain CDC48_2 PF02933.17 EMR69214.1 - 5.2e-05 23.0 1.2 0.00011 21.9 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 EMR69214.1 - 0.00011 21.7 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_lid_3 PF17862.1 EMR69214.1 - 0.00011 21.9 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EMR69214.1 - 0.0002 21.2 0.0 0.00067 19.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EMR69214.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EMR69214.1 - 0.0032 17.2 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 EMR69214.1 - 0.0074 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EMR69214.1 - 0.013 15.5 0.0 0.05 13.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EMR69214.1 - 0.014 14.6 0.0 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_22 PF13401.6 EMR69214.1 - 0.017 15.4 0.0 0.41 10.9 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMR69214.1 - 0.037 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMR69214.1 - 0.075 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EMR69214.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EMR69214.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMR69214.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EMR69214.1 - 0.14 12.3 0.0 0.58 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain She9_MDM33 PF05546.11 EMR69215.1 - 1.5e-77 259.9 3.3 2.2e-77 259.4 3.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family CENP-F_leu_zip PF10473.9 EMR69215.1 - 0.03 14.4 0.8 1.9 8.5 0.0 2.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SIKE PF05769.11 EMR69215.1 - 0.044 13.7 0.4 0.91 9.4 0.4 2.3 1 1 0 1 1 1 0 SIKE family ZapB PF06005.12 EMR69215.1 - 0.12 12.8 7.1 0.24 11.9 0.1 3.0 3 0 0 3 3 3 0 Cell division protein ZapB PsbH PF00737.20 EMR69215.1 - 0.29 10.9 0.8 0.53 10.1 0.8 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein LemA PF04011.12 EMR69215.1 - 1 9.2 6.6 3.5 7.5 0.1 2.6 3 0 0 3 3 3 0 LemA family GST_N_4 PF17172.4 EMR69216.1 - 9.8e-20 71.2 0.0 1.9e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EMR69216.1 - 3.1e-17 62.1 0.0 9e-17 60.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EMR69216.1 - 1.3e-09 38.4 0.0 3.1e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 EMR69216.1 - 0.00072 19.5 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 EMR69216.1 - 0.0047 17.2 0.2 0.017 15.4 0.2 1.9 1 1 0 2 2 2 1 SAM35, subunit of SAM coomplex RGS PF00615.19 EMR69217.1 - 2.8e-10 40.5 0.0 8.6e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain Pro-kuma_activ PF09286.11 EMR69218.1 - 1.5e-38 132.3 0.1 3.2e-38 131.2 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMR69218.1 - 2e-07 30.6 0.4 4.1e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 Subtilase family DAO PF01266.24 EMR69221.1 - 1.1e-39 137.0 6.8 1.2e-39 136.9 6.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR69221.1 - 3.6e-05 23.9 0.3 0.00033 20.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR69221.1 - 0.00047 19.5 0.1 0.0012 18.1 0.1 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EMR69221.1 - 0.00061 19.0 0.0 0.00094 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR69221.1 - 0.00097 18.5 0.1 0.07 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR69221.1 - 0.0053 17.3 0.1 0.026 15.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR69221.1 - 0.022 13.8 0.3 3.2 6.7 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMR69221.1 - 0.072 13.1 0.1 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EMR69221.1 - 0.16 10.6 0.1 0.49 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 EMR69221.1 - 0.18 10.7 0.1 0.45 9.3 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase CP12 PF02672.15 EMR69222.1 - 0.0016 19.1 0.1 0.0031 18.2 0.1 1.5 1 0 0 1 1 1 1 CP12 domain Helo_like_N PF17111.5 EMR69222.1 - 0.041 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins NPV_P10 PF05531.12 EMR69222.1 - 0.063 13.7 0.5 35 4.9 0.3 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF848 PF05852.11 EMR69222.1 - 0.31 11.1 2.8 2.8 8.0 2.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Sedlin_N PF04628.13 EMR69223.1 - 2.1e-13 50.5 0.0 3.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EMR69223.1 - 0.23 11.4 0.0 3.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family MFS_1 PF07690.16 EMR69224.1 - 2e-32 112.5 31.7 2e-32 112.5 31.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR69224.1 - 1.8e-06 26.7 3.6 1.8e-06 26.7 3.6 2.3 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_5_2 PF16079.5 EMR69224.1 - 0.17 12.2 1.2 0.79 10.1 0.2 2.6 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V eIF-1a PF01176.19 EMR69225.1 - 1.4e-22 79.2 0.0 1.8e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 FAD_binding_4 PF01565.23 EMR69226.1 - 1.9e-23 82.7 1.8 1.2e-22 80.2 1.8 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EMR69226.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like HAD PF12710.7 EMR69227.1 - 1.3e-23 84.4 0.0 1.9e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EMR69227.1 - 0.0039 16.6 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.12 EMR69227.1 - 0.02 14.4 0.0 0.069 12.7 0.0 1.8 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EMR69227.1 - 0.2 11.9 1.2 17 5.6 0.0 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Isochorismatase PF00857.20 EMR69228.1 - 4.3e-37 128.0 0.0 5.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family OTU PF02338.19 EMR69229.1 - 1.9e-21 76.9 0.1 2.4e-16 60.4 0.0 2.9 2 1 1 3 3 3 2 OTU-like cysteine protease Peptidase_C65 PF10275.9 EMR69229.1 - 3.5e-05 23.4 0.0 0.018 14.5 0.0 2.6 1 1 1 2 2 2 2 Peptidase C65 Otubain RhlB PF12300.8 EMR69229.1 - 9.9 6.3 19.9 0.031 14.4 9.5 2.2 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Chitin_synth_1 PF01644.17 EMR69230.1 - 1.4e-69 233.3 0.0 2e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EMR69230.1 - 9.8e-28 95.9 0.0 1.8e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EMR69230.1 - 1.3e-24 86.8 0.0 8.2e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EMR69230.1 - 6.8e-09 35.9 0.0 6.8e-09 35.9 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 ORC4_C PF14629.6 EMR69232.1 - 7.9e-65 218.3 0.0 8.9e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus 7TM_GPCR_Sru PF10322.9 EMR69234.1 - 0.028 13.8 0.1 0.028 13.8 0.1 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru VWA PF00092.28 EMR69235.1 - 0.043 14.1 0.0 0.26 11.5 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain Syndecan PF01034.20 EMR69237.1 - 0.0041 17.0 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain SNAP-25 PF00835.19 EMR69238.1 - 0.062 13.6 0.7 0.11 12.8 0.2 1.6 2 0 0 2 2 2 0 SNAP-25 family Ribosomal_S25 PF03297.15 EMR69238.1 - 0.84 9.9 6.3 2.3 8.4 6.2 1.7 1 1 1 2 2 2 0 S25 ribosomal protein MFS_1 PF07690.16 EMR69239.1 - 2e-23 82.9 39.6 2e-16 59.9 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MSA-2c PF12238.8 EMR69239.1 - 0.0017 18.4 0.2 0.003 17.6 0.2 1.3 1 0 0 1 1 1 1 Merozoite surface antigen 2c FYVE_2 PF02318.16 EMR69240.1 - 0.074 13.3 12.6 0.62 10.3 1.0 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger F-box-like PF12937.7 EMR69242.1 - 2.4e-06 27.3 0.3 7.3e-06 25.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR69242.1 - 0.04 13.8 0.5 0.04 13.8 0.5 2.1 2 0 0 2 2 2 0 F-box domain DUF3638 PF12340.8 EMR69244.1 - 4.9e-62 209.2 0.0 1.1e-39 136.1 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EMR69244.1 - 3.9e-17 61.3 0.5 7.5e-17 60.4 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PKD_channel PF08016.12 EMR69244.1 - 0.21 10.2 0.3 0.37 9.4 0.3 1.3 1 0 0 1 1 1 0 Polycystin cation channel Pkinase PF00069.25 EMR69247.1 - 3.7e-60 203.5 0.0 9.3e-60 202.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR69247.1 - 1.1e-35 123.3 0.0 1.6e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EMR69247.1 - 4.1e-27 94.1 19.4 2e-13 50.3 5.3 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 EMR69247.1 - 3.5e-14 53.2 0.9 1.4e-13 51.3 0.9 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EMR69247.1 - 0.00011 22.5 0.1 0.00021 21.6 0.1 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EMR69247.1 - 0.028 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EMR69247.1 - 0.034 13.8 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EMR69247.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 EMR69248.1 - 1.3e-13 50.9 0.0 6.4e-11 42.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain APH PF01636.23 EMR69248.1 - 0.0017 18.3 0.7 0.0078 16.2 0.7 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EMR69248.1 - 0.0031 16.9 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH_6_hur PF04655.14 EMR69248.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase MFS_1 PF07690.16 EMR69249.1 - 1.3e-42 146.0 31.0 1.3e-42 146.0 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMR69249.1 - 0.0016 16.8 4.3 0.023 13.0 4.3 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Aldedh PF00171.22 EMR69250.1 - 1.6e-18 66.5 6.5 2.7e-10 39.3 4.8 2.8 1 1 1 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 EMR69250.1 - 0.0017 17.6 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) eIF-5_eIF-2B PF01873.17 EMR69251.1 - 1.2e-41 141.2 0.4 2.5e-41 140.2 0.4 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 K_channel_TID PF07941.11 EMR69252.1 - 0.056 13.9 1.9 0.056 13.9 1.9 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ALG3 PF05208.13 EMR69253.1 - 4.8e-143 476.9 15.7 5.9e-143 476.6 15.7 1.0 1 0 0 1 1 1 1 ALG3 protein Thioredoxin PF00085.20 EMR69254.1 - 1.5e-24 86.0 0.0 1.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EMR69254.1 - 2.5e-07 31.0 0.0 2e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EMR69254.1 - 9.3e-07 28.5 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EMR69254.1 - 2e-06 28.2 0.1 7e-06 26.5 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EMR69254.1 - 6.6e-06 26.2 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EMR69254.1 - 1.4e-05 24.8 0.1 2.2e-05 24.2 0.1 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMR69254.1 - 1.8e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EMR69254.1 - 0.0035 17.1 0.0 0.0045 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EMR69254.1 - 0.0041 17.0 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 EMR69254.1 - 0.0054 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 EMR69254.1 - 0.045 13.4 0.0 0.71 9.5 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin DUF2347 PF09804.9 EMR69255.1 - 4.9e-72 242.9 0.0 9.3e-48 163.2 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EMR69255.1 - 1.3e-66 224.7 0.0 3.2e-66 223.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) FSA_C PF10479.9 EMR69255.1 - 1.3 7.0 4.1 2 6.4 4.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TMEM154 PF15102.6 EMR69255.1 - 7.2 6.5 7.3 17 5.3 7.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family Ank_2 PF12796.7 EMR69256.1 - 4.2e-50 168.3 4.7 1.9e-13 50.8 0.4 6.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR69256.1 - 6.1e-45 151.0 3.6 6.8e-10 39.3 0.0 7.3 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EMR69256.1 - 1.2e-42 142.6 15.7 0.0001 22.6 0.3 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 EMR69256.1 - 2.5e-39 128.8 5.2 0.00038 20.7 0.0 10.7 9 1 1 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 EMR69256.1 - 1.4e-38 130.4 6.6 6.4e-09 35.9 0.0 8.1 3 1 5 9 9 9 7 Ankyrin repeats (many copies) SPRY PF00622.28 EMR69256.1 - 6e-06 26.4 0.7 1.3e-05 25.3 0.7 1.5 1 0 0 1 1 1 1 SPRY domain DUF1843 PF08898.10 EMR69256.1 - 0.0091 16.5 0.0 13 6.3 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF1843) DUF1264 PF06884.11 EMR69257.1 - 2.9e-75 251.6 0.0 4.8e-75 250.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) HET PF06985.11 EMR69257.1 - 8e-21 74.9 0.0 1.5e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) KR PF08659.10 EMR69258.1 - 1.8e-22 80.1 0.1 3.4e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 KR domain DnaJ PF00226.31 EMR69258.1 - 4.3e-15 55.6 0.4 1.1e-14 54.3 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain PP-binding PF00550.25 EMR69258.1 - 7.9e-11 42.2 1.8 8.8e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Sec63 PF02889.16 EMR69258.1 - 2.2e-09 36.9 0.0 2.1e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain Acatn PF13000.7 EMR69258.1 - 0.046 12.2 0.0 0.071 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 Enkurin PF13864.6 EMR69258.1 - 0.12 12.8 0.2 0.43 11.0 0.2 1.9 1 0 0 1 1 1 0 Calmodulin-binding Sugar_tr PF00083.24 EMR69259.1 - 3.3e-10 39.4 2.6 3.3e-10 39.4 2.6 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter CoA_transf_3 PF02515.17 EMR69260.1 - 0.016 14.4 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III p450 PF00067.22 EMR69261.1 - 2.4e-35 122.2 0.0 6.5e-35 120.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_C9 PF01707.16 EMR69261.1 - 0.035 13.7 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C9 DUF202 PF02656.15 EMR69262.1 - 3.6 8.1 6.2 20 5.7 2.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF1275 PF06912.11 EMR69263.1 - 6.1e-44 150.2 15.9 7.7e-44 149.9 15.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4229 PF14012.6 EMR69263.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) BDV_G PF06208.11 EMR69263.1 - 0.17 11.0 0.0 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Borna disease virus G protein OB_NTP_bind PF07717.16 EMR69264.1 - 1.5e-10 41.3 0.1 6.2e-10 39.3 0.1 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EMR69264.1 - 2.6e-08 34.1 0.1 0.0014 18.8 0.0 2.7 2 1 0 2 2 2 2 Helicase associated domain (HA2) Thymidylate_kin PF02223.17 EMR69264.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase VirE PF05272.11 EMR69264.1 - 0.016 15.0 0.0 0.83 9.3 0.0 2.3 1 1 1 2 2 2 0 Virulence-associated protein E Bac_luciferase PF00296.20 EMR69265.1 - 1.9e-49 168.8 0.0 2.6e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase COesterase PF00135.28 EMR69266.1 - 8.1e-43 147.1 0.0 6.1e-29 101.3 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR69266.1 - 0.006 16.5 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold SnoaL_2 PF12680.7 EMR69267.1 - 0.049 14.3 0.3 0.13 13.0 0.2 1.7 1 1 1 2 2 2 0 SnoaL-like domain F_bP_aldolase PF01116.20 EMR69269.1 - 2.2e-75 253.8 0.0 3e-51 174.5 0.0 2.5 2 1 0 2 2 2 2 Fructose-bisphosphate aldolase class-II NYD-SP28_assoc PF14775.6 EMR69269.1 - 0.14 12.3 0.3 0.14 12.3 0.3 2.7 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF3824 PF12868.7 EMR69270.1 - 0.004 17.8 5.9 0.004 17.8 5.9 6.5 2 2 4 6 6 6 1 Domain of unknwon function (DUF3824) DUF3632 PF12311.8 EMR69271.1 - 5.5e-28 98.6 0.1 3.2e-27 96.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) TERF2_RBM PF16772.5 EMR69271.1 - 0.11 11.9 0.1 7.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Telomeric repeat-binding factor 2 Rap1-binding motif RSN1_7TM PF02714.15 EMR69272.1 - 1.1e-80 271.0 23.4 2.4e-80 269.8 22.7 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMR69272.1 - 5e-31 107.6 0.0 1.5e-30 106.0 0.0 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMR69272.1 - 5.9e-18 65.7 0.1 9.1e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 EMR69272.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4291 PF14124.6 EMR69273.1 - 9.1e-58 195.1 0.0 9.1e-58 195.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4291) MFS_1 PF07690.16 EMR69273.1 - 3.4e-06 26.2 13.7 0.0029 16.6 0.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF917 PF06032.12 EMR69274.1 - 2.4e-52 177.9 0.0 1.3e-35 122.8 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF917) KR PF08659.10 EMR69275.1 - 1.4e-51 175.0 0.8 4.3e-51 173.4 0.3 2.2 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.26 EMR69275.1 - 3e-50 171.1 0.7 8.6e-49 166.4 0.7 2.5 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EMR69275.1 - 1.1e-48 166.4 0.1 1.2e-46 159.7 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR69275.1 - 6.1e-35 119.8 1.5 7.6e-35 119.5 0.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EMR69275.1 - 1.5e-27 96.6 0.9 6.5e-27 94.5 0.1 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EMR69275.1 - 1.7e-17 64.0 0.0 5.2e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EMR69275.1 - 1.7e-15 58.2 0.0 6.6e-14 53.1 0.0 3.3 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR69275.1 - 4.2e-15 55.9 0.3 3.1e-14 53.1 0.1 2.6 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EMR69275.1 - 1.5e-11 44.4 0.0 4.9e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 EMR69275.1 - 3.6e-11 42.9 0.0 1.2e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 EMR69275.1 - 1e-09 39.0 0.0 3.5e-09 37.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR69275.1 - 1.8e-09 37.6 0.0 4.6e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR69275.1 - 2.8e-08 34.3 0.0 7.6e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR69275.1 - 3.4e-08 33.7 0.0 8.5e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 EMR69275.1 - 5.3e-06 26.2 0.0 1.7e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 EMR69275.1 - 0.00036 20.0 0.0 0.0013 18.1 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 EMR69275.1 - 0.00069 19.5 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KAsynt_C_assoc PF16197.5 EMR69275.1 - 0.00072 20.0 0.2 0.0035 17.8 0.0 2.3 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_16 PF10294.9 EMR69275.1 - 0.001 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 EMR69275.1 - 0.002 17.6 0.1 0.0041 16.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EMR69275.1 - 0.0064 16.3 0.5 0.017 14.9 0.5 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_28 PF02636.17 EMR69275.1 - 0.065 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3606 PF12244.8 EMR69275.1 - 0.14 12.2 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Methyltransf_2 PF00891.18 EMR69275.1 - 0.18 11.1 0.0 0.42 9.9 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain Macoilin PF09726.9 EMR69276.1 - 0.0082 14.8 1.1 0.0098 14.5 1.1 1.2 1 0 0 1 1 1 1 Macoilin family PepSY_TM PF03929.16 EMR69276.1 - 1 9.0 5.4 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 PepSY-associated TM region Paramyxo_ncap PF00973.19 EMR69276.1 - 3.4 6.5 7.8 4.6 6.0 7.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein BAF1_ABF1 PF04684.13 EMR69276.1 - 3.7 6.5 13.5 5.8 5.9 13.5 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SnoaL_4 PF13577.6 EMR69277.1 - 2.3e-12 47.1 0.5 2.8e-12 46.9 0.5 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EMR69277.1 - 0.033 14.6 0.3 0.044 14.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF5132 PF17195.4 EMR69278.1 - 0.022 14.9 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) MerR_2 PF13591.6 EMR69278.1 - 0.16 11.8 0.2 0.38 10.6 0.2 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein Fic PF02661.18 EMR69279.1 - 1.7e-12 48.1 0.0 3.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family TOPRIM_C PF16898.5 EMR69279.1 - 0.039 14.2 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM DAPG_hydrolase PF18089.1 EMR69279.1 - 0.046 13.3 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain Peroxidase_2 PF01328.17 EMR69281.1 - 9.4e-17 62.1 0.1 1.2e-16 61.8 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.16 EMR69282.1 - 1.5e-10 40.6 27.0 1e-07 31.2 10.2 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily DUF4083 PF13314.6 EMR69282.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Glyco_hydro_10 PF00331.20 EMR69283.1 - 2.8e-16 59.6 0.0 3.3e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GHL6 PF14871.6 EMR69284.1 - 9.1e-27 93.9 0.0 1.7e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 GHL10 PF02638.15 EMR69284.1 - 4.3e-08 32.6 0.0 6.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Glyco_hydro_42M PF08532.10 EMR69284.1 - 2e-05 24.2 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42 PF02449.15 EMR69284.1 - 0.00022 20.7 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase MARVEL PF01284.23 EMR69286.1 - 1.8e-09 37.8 19.9 3.3e-09 36.9 16.9 2.1 1 1 1 2 2 2 1 Membrane-associating domain adh_short PF00106.25 EMR69287.1 - 5.3e-17 61.9 0.8 8.4e-17 61.3 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69287.1 - 7.1e-14 51.9 0.8 9.4e-14 51.5 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR69287.1 - 2.6e-05 24.2 0.5 3e-05 24.0 0.5 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMR69287.1 - 0.089 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Helicase_RecD PF05127.14 EMR69287.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Helicase DUF1409 PF07197.12 EMR69287.1 - 0.17 11.8 0.2 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) EamA PF00892.20 EMR69288.1 - 0.0014 18.8 30.3 0.0018 18.4 6.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF1077 PF06417.12 EMR69288.1 - 0.03 14.3 3.8 0.64 10.0 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1077) VCBS PF13517.6 EMR69289.1 - 3.4e-25 88.4 57.1 6.8e-10 39.4 3.1 9.7 5 2 4 9 9 9 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EMR69289.1 - 1.4e-12 48.3 0.3 4.7e-12 46.7 0.3 2.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 EMR69289.1 - 9.9e-06 25.0 7.2 0.46 9.8 0.0 6.1 5 2 2 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 EMR69289.1 - 0.0026 17.8 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 EMR69289.1 - 0.2 11.8 35.0 0.1 12.8 1.0 6.8 6 0 0 6 6 6 0 FG-GAP repeat MFS_1 PF07690.16 EMR69290.1 - 1.6e-31 109.6 28.9 2e-25 89.5 7.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR69290.1 - 1.2e-09 37.5 4.6 1.2e-09 37.5 4.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.16 EMR69290.1 - 0.12 10.5 7.9 0.87 7.7 1.9 2.2 2 0 0 2 2 2 0 BT1 family MFS_3 PF05977.13 EMR69290.1 - 0.18 10.1 4.2 1.2 7.4 3.2 2.2 1 1 1 2 2 2 0 Transmembrane secretion effector Antimicrobial24 PF16049.5 EMR69290.1 - 2.8 8.0 5.6 17 5.5 0.2 2.6 2 0 0 2 2 2 0 Frog antimicrobial peptide MFS_1_like PF12832.7 EMR69290.1 - 4.3 6.1 14.4 0.013 14.4 1.9 2.4 2 1 0 2 2 2 0 MFS_1 like family ThiS PF02597.20 EMR69291.1 - 3.3e-09 37.3 0.0 5e-09 36.7 0.0 1.3 1 1 0 1 1 1 1 ThiS family AAA PF00004.29 EMR69292.1 - 3.1e-40 137.6 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMR69292.1 - 7.3e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EMR69292.1 - 8.2e-05 22.6 0.1 0.00062 19.8 0.0 2.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMR69292.1 - 0.00015 22.1 0.0 0.0055 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EMR69292.1 - 0.00048 20.3 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EMR69292.1 - 0.00072 20.0 0.1 0.014 15.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EMR69292.1 - 0.0018 17.5 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EMR69292.1 - 0.0089 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EMR69292.1 - 0.025 14.8 0.0 0.063 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMR69292.1 - 0.028 13.9 0.0 0.085 12.4 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EMR69292.1 - 0.041 14.3 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 EMR69292.1 - 0.05 13.3 0.1 0.6 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMR69292.1 - 0.051 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EMR69292.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMR69292.1 - 0.092 12.5 0.1 0.28 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMR69292.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMR69292.1 - 0.14 12.7 0.0 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain SNase PF00565.17 EMR69293.1 - 4.8e-23 81.7 0.0 5.8e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PP2C PF00481.21 EMR69295.1 - 9.5e-55 186.0 0.0 1.9e-54 185.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EMR69295.1 - 4.2e-41 138.5 57.3 1.7e-10 40.5 1.0 9.7 6 3 5 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 EMR69295.1 - 2.2e-35 120.1 62.2 2.4e-06 27.8 4.3 12.4 7 2 1 12 12 12 9 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EMR69295.1 - 8.3e-29 100.5 0.0 6.5e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 EMR69295.1 - 5.9e-09 35.3 44.0 5.7 7.9 2.4 16.3 15 3 0 15 15 15 2 Leucine Rich Repeat LRR_9 PF14580.6 EMR69295.1 - 7.2e-07 28.9 16.4 0.013 15.0 0.7 4.5 2 1 1 4 4 4 4 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 EMR69295.1 - 1.4e-05 24.7 0.4 4e-05 23.3 0.4 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.23 EMR69295.1 - 0.00027 21.5 0.1 0.00091 19.8 0.1 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RTC4 PF14474.6 EMR69297.1 - 2.2e-36 124.7 0.0 2.9e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 RTC4-like domain Cul7 PF11515.8 EMR69297.1 - 0.0017 18.6 0.1 0.39 11.0 0.1 2.4 2 1 0 2 2 2 2 Mouse development and cellular proliferation protein Cullin-7 Mob1_phocein PF03637.17 EMR69298.1 - 8.7e-28 97.4 0.0 1.8e-27 96.5 0.0 1.4 1 1 0 1 1 1 1 Mob1/phocein family LRR_4 PF12799.7 EMR69301.1 - 0.02 15.3 1.1 7.6 7.1 0.1 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Prenylcys_lyase PF07156.14 EMR69302.1 - 7.9e-18 64.7 0.0 8.4e-08 31.7 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase Amino_oxidase PF01593.24 EMR69302.1 - 0.0047 16.3 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EMR69302.1 - 0.04 13.5 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3336 PF11815.8 EMR69303.1 - 2.7e-32 111.4 0.1 3.6e-31 107.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EMR69303.1 - 3.9e-12 46.8 1.7 6.6e-12 46.0 0.4 2.1 2 1 0 2 2 2 1 Patatin-like phospholipase LSM PF01423.22 EMR69304.1 - 7.7e-18 64.0 0.0 1e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMR69304.1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 EMR69304.1 - 1.4 7.6 8.0 1.8 7.3 8.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_S28e PF01200.18 EMR69305.1 - 1.5e-31 108.2 2.2 1.6e-31 108.1 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Dynamitin PF04912.14 EMR69306.1 - 1.1e-109 367.3 8.3 1.3e-109 367.1 8.3 1.1 1 0 0 1 1 1 1 Dynamitin Phage_GP20 PF06810.11 EMR69306.1 - 0.00026 20.8 9.9 0.0051 16.6 0.8 3.3 3 0 0 3 3 3 1 Phage minor structural protein GP20 FH2 PF02181.23 EMR69306.1 - 0.0071 15.5 3.6 1 8.4 0.1 2.9 3 0 0 3 3 3 1 Formin Homology 2 Domain DUF1192 PF06698.11 EMR69306.1 - 0.0094 16.0 10.0 0.81 9.8 0.6 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1192) Laminin_II PF06009.12 EMR69306.1 - 0.012 15.6 14.1 0.029 14.4 0.2 4.1 4 1 1 5 5 4 0 Laminin Domain II DUF1664 PF07889.12 EMR69306.1 - 0.024 14.7 4.1 0.47 10.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EMR69306.1 - 0.053 13.8 4.7 2.9 8.2 0.1 3.5 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 EMR69306.1 - 0.068 13.6 7.3 7.1 7.2 0.3 3.7 3 0 0 3 3 3 0 Cell division protein ZapB BST2 PF16716.5 EMR69306.1 - 0.069 13.7 9.3 0.25 12.0 0.3 3.4 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 Occludin_ELL PF07303.13 EMR69306.1 - 0.073 13.8 0.7 6.9 7.5 0.0 3.2 3 0 0 3 3 3 0 Occludin homology domain THP2 PF09432.10 EMR69306.1 - 0.1 12.6 0.1 0.33 11.0 0.1 1.9 1 0 0 1 1 1 0 Tho complex subunit THP2 GTP-bdg_M PF16360.5 EMR69306.1 - 0.11 13.1 11.5 2.4 8.8 0.1 3.5 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region Jnk-SapK_ap_N PF09744.9 EMR69306.1 - 0.3 11.3 7.0 0.83 9.9 0.1 3.1 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.6 EMR69306.1 - 0.31 11.5 7.3 1.5 9.3 0.1 3.8 3 2 0 3 3 3 0 Snapin/Pallidin BRE1 PF08647.11 EMR69306.1 - 0.31 11.1 6.9 1.7 8.8 0.2 3.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 EMR69306.1 - 0.37 10.9 16.8 1.4 9.0 1.0 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 EMR69306.1 - 0.37 11.0 10.5 3.4 7.9 0.2 3.3 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.9 EMR69306.1 - 0.54 10.5 9.4 1.3 9.3 0.1 4.0 4 1 0 4 4 3 0 Haemolysin XhlA Sipho_Gp157 PF05565.11 EMR69306.1 - 0.6 10.1 6.1 0.74 9.8 0.1 2.8 3 0 0 3 3 3 0 Siphovirus Gp157 Golgin_A5 PF09787.9 EMR69306.1 - 0.84 9.0 12.0 1.2 8.5 1.5 3.1 3 0 0 3 3 3 0 Golgin subfamily A member 5 Bacillus_HBL PF05791.11 EMR69306.1 - 0.87 9.4 4.7 32 4.3 0.0 3.1 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Prefoldin_2 PF01920.20 EMR69306.1 - 0.96 9.4 9.2 4.7 7.2 0.1 3.7 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.10 EMR69306.1 - 1 9.6 4.4 30 4.8 0.0 3.4 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family YkyA PF10368.9 EMR69306.1 - 1.1 8.9 4.9 1.6 8.4 0.1 2.9 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein DHR10 PF18595.1 EMR69306.1 - 1.1 9.3 17.3 2.1 8.5 1.2 3.6 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Spore_III_AB PF09548.10 EMR69306.1 - 2 8.5 7.1 1.8 8.7 1.1 3.0 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) LPP PF04728.13 EMR69306.1 - 2.8 8.4 9.8 5.7 7.4 0.6 4.0 4 0 0 4 4 3 0 Lipoprotein leucine-zipper DUF4140 PF13600.6 EMR69306.1 - 3.5 8.1 10.1 4.1 7.9 0.4 3.7 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 EMR69306.1 - 4 8.0 18.6 3.4 8.2 1.4 3.3 2 1 0 3 3 3 0 Apg6 coiled-coil region DUF4200 PF13863.6 EMR69306.1 - 4.3 7.8 8.1 23 5.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Rx_N PF18052.1 EMR69306.1 - 4.8 7.5 7.6 0.55 10.5 0.8 2.7 3 1 0 3 3 3 0 Rx N-terminal domain MRPL52 PF18699.1 EMR69306.1 - 6.3 7.1 7.8 1.8 8.8 0.4 2.8 3 0 0 3 3 2 0 Mitoribosomal protein mL52 DUF724 PF05266.14 EMR69306.1 - 6.7 6.5 10.2 5.9 6.7 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) GrpE PF01025.19 EMR69306.1 - 6.8 6.3 8.8 0.72 9.5 0.6 3.0 3 1 1 4 4 4 0 GrpE Spc24 PF08286.11 EMR69306.1 - 7 6.9 10.9 22 5.3 0.7 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Filament PF00038.21 EMR69306.1 - 7.5 6.0 10.5 9.6 5.7 0.8 3.1 3 0 0 3 3 3 0 Intermediate filament protein Ax_dynein_light PF10211.9 EMR69306.1 - 9.5 6.1 10.4 3.4 7.6 1.0 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain Cpn60_TCP1 PF00118.24 EMR69307.1 - 7.7e-146 486.6 14.1 8.6e-146 486.4 14.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 EMR69307.1 - 0.11 12.2 0.3 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Phage Tail Protein X Ysc84 PF04366.12 EMR69308.1 - 4.6e-34 116.9 0.0 9e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator Actin PF00022.19 EMR69309.1 - 4.3e-08 32.2 0.1 6.2e-07 28.4 0.0 2.7 4 0 0 4 4 4 1 Actin FtsA PF14450.6 EMR69309.1 - 0.18 12.2 2.4 1.4 9.4 2.4 2.3 1 1 0 1 1 1 0 Cell division protein FtsA Leo1 PF04004.13 EMR69310.1 - 3.3e-32 111.6 0.9 3.3e-32 111.6 0.9 1.9 2 0 0 2 2 2 1 Leo1-like protein CPSF100_C PF13299.6 EMR69310.1 - 9.1 6.4 9.8 5.1 7.3 2.1 2.9 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Rax2 PF12768.7 EMR69311.1 - 2.9e-72 242.6 2.4 1.5e-71 240.3 0.2 3.3 4 0 0 4 4 4 1 Cortical protein marker for cell polarity Kelch_1 PF01344.25 EMR69311.1 - 0.00058 19.4 2.2 0.048 13.2 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 EMR69311.1 - 0.001 19.0 10.4 0.0091 16.0 0.2 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF5122 PF17164.4 EMR69311.1 - 0.017 15.4 15.0 0.2 12.0 0.0 6.9 7 0 0 7 7 7 0 Domain of unknown function (DUF5122) beta-propeller tRNA-synt_2 PF00152.20 EMR69312.1 - 1.4e-76 257.5 0.4 2.2e-76 256.9 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMR69312.1 - 4.6e-10 39.4 0.0 1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMR69312.1 - 3.3e-07 30.0 0.0 0.00065 19.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_S49_N PF08496.10 EMR69312.1 - 3.8 7.6 6.3 8.5 6.4 6.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkr1 PF08636.10 EMR69313.1 - 6.6e-32 109.5 6.6 8.5e-32 109.1 6.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.20 EMR69313.1 - 0.024 13.1 0.1 0.028 12.9 0.1 1.0 1 0 0 1 1 1 0 FHIPEP family OAD_gamma PF04277.13 EMR69313.1 - 0.055 14.1 0.5 0.14 12.8 0.5 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PepSY_TM PF03929.16 EMR69313.1 - 0.07 12.8 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region RCC1 PF00415.18 EMR69314.1 - 2.1e-41 140.3 3.9 1.7e-08 34.9 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMR69314.1 - 8.1e-22 76.5 14.6 2.4e-06 27.2 0.1 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PLRV_ORF5 PF01690.17 EMR69314.1 - 9.8 4.8 6.6 14 4.2 6.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FAS_I_H PF18314.1 EMR69315.1 - 1.1e-74 250.5 0.1 2.8e-74 249.1 0.1 1.8 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EMR69315.1 - 3.4e-73 245.3 0.0 6.8e-73 244.4 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EMR69315.1 - 5.7e-20 72.0 0.1 1.4e-19 70.7 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EMR69315.1 - 1.9e-16 60.2 0.1 4.8e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EMR69315.1 - 1.2e-12 47.8 0.0 3.2e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EMR69315.1 - 0.00096 19.1 0.0 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 KR domain RicinB_lectin_2 PF14200.6 EMR69316.1 - 2.2e-05 25.1 0.2 5.4e-05 23.8 0.0 1.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DFRP_C PF16543.5 EMR69316.1 - 0.16 12.5 0.4 2.3 8.8 0.4 2.0 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 DUF1729 PF08354.10 EMR69317.1 - 1.2e-159 530.9 0.0 2.2e-159 530.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EMR69317.1 - 6.6e-88 295.3 0.0 1e-85 288.1 0.0 3.4 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 EMR69317.1 - 1.1e-54 184.2 0.0 3.2e-54 182.7 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 EMR69317.1 - 3e-42 143.7 0.0 7.5e-42 142.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 EMR69317.1 - 3.7e-38 129.9 0.0 7.2e-38 128.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 EMR69317.1 - 4.2e-35 121.6 0.0 7.6e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 EMR69317.1 - 7e-23 81.2 0.0 2.3e-22 79.6 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 EMR69317.1 - 0.013 14.9 0.7 0.54 9.6 0.7 2.6 1 1 0 1 1 1 0 Nitronate monooxygenase Pox_Ag35 PF03286.14 EMR69318.1 - 0.74 9.6 14.2 0.42 10.4 3.4 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TMEM214 PF10151.9 EMR69318.1 - 5.7 5.3 8.7 7.1 5.0 8.7 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Phage-MuB_C PF09077.11 EMR69320.1 - 0.049 13.5 1.6 0.12 12.3 0.9 2.0 2 0 0 2 2 2 0 Mu B transposition protein, C terminal Zn_clus PF00172.18 EMR69321.1 - 4e-09 36.4 7.9 4e-09 36.4 7.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR69321.1 - 0.091 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain CC190 PF15768.5 EMR69321.1 - 0.16 12.0 0.7 0.25 11.3 0.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 ACBP PF00887.19 EMR69322.1 - 9.8e-24 83.4 1.2 1.1e-23 83.2 1.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.32 EMR69323.1 - 9.8e-13 48.4 0.8 0.14 13.1 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR69323.1 - 0.084 13.2 0.0 38 4.7 0.0 3.5 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3431 PF11913.8 EMR69324.1 - 5.2e-87 291.1 0.0 6.4e-87 290.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) BCIP PF13862.6 EMR69325.1 - 5.8e-68 228.7 0.0 7.2e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.32 EMR69326.1 - 3.3e-29 100.5 13.2 2.9e-06 27.9 0.7 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR69326.1 - 8.1e-09 35.7 0.2 0.1 12.9 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR69326.1 - 1.1e-05 24.3 6.5 1.1 7.8 0.3 4.9 3 2 2 5 5 5 4 Nucleoporin Nup120/160 DUF5046 PF16465.5 EMR69326.1 - 0.0013 18.2 0.5 0.39 10.1 0.0 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF5046) Seryl_tRNA_N PF02403.22 EMR69326.1 - 0.061 13.6 1.2 0.16 12.2 1.2 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Suppressor_APC PF11414.8 EMR69326.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.1 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein zf-RING_2 PF13639.6 EMR69327.1 - 4.1e-08 33.4 3.4 4.1e-08 33.4 3.4 3.0 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMR69327.1 - 8.5e-08 31.9 20.3 1.1e-07 31.6 3.8 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMR69327.1 - 2.6e-06 27.3 6.3 2.6e-06 27.3 6.3 2.7 2 1 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EMR69327.1 - 5.8e-06 26.1 8.7 5.8e-06 26.1 8.7 2.9 2 1 1 3 3 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EMR69327.1 - 1.7e-05 24.5 4.3 1.7e-05 24.5 4.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMR69327.1 - 0.00021 21.1 7.6 0.00021 21.1 7.6 2.9 3 1 1 4 4 3 2 Zinc finger, C3HC4 type (RING finger) UPF0492 PF15744.5 EMR69327.1 - 0.0066 15.7 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0492 zf-C3HC4_4 PF15227.6 EMR69327.1 - 0.0078 16.3 3.5 0.0078 16.3 3.5 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EMR69327.1 - 0.02 15.2 18.4 0.051 13.9 14.7 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain DUF2390 PF09523.10 EMR69327.1 - 0.063 13.6 1.6 0.099 13.0 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) zf-RING_UBOX PF13445.6 EMR69327.1 - 2.5 8.2 19.8 0.39 10.8 10.8 3.7 2 1 1 3 3 3 0 RING-type zinc-finger Tyr-DNA_phospho PF06087.12 EMR69328.1 - 2.1e-128 428.9 0.0 2.6e-128 428.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase ATP_bind_1 PF03029.17 EMR69329.1 - 3.7e-78 262.7 0.0 4.9e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EMR69329.1 - 0.0048 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EMR69329.1 - 0.033 13.5 0.0 0.098 11.9 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_31 PF13614.6 EMR69329.1 - 0.034 14.1 0.0 2.1 8.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMR69329.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ImcF-related_N PF14331.6 EMR69329.1 - 0.051 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain MMR_HSR1 PF01926.23 EMR69329.1 - 0.063 13.4 0.0 0.78 9.8 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMR69329.1 - 0.1 12.1 0.0 0.68 9.4 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain KTI12 PF08433.10 EMR69329.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 EMR69329.1 - 0.68 10.4 1.8 0.64 10.4 0.2 1.8 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.14 EMR69330.1 - 0.079 11.2 8.1 0.11 10.7 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 EMR69330.1 - 0.091 13.1 11.3 0.18 12.1 11.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 EMR69330.1 - 0.15 10.8 3.8 0.19 10.5 3.8 1.1 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 EMR69330.1 - 0.24 10.8 10.7 0.31 10.4 10.7 1.1 1 0 0 1 1 1 0 SDA1 Insulin PF00049.18 EMR69330.1 - 0.34 11.9 3.5 1 10.4 3.5 1.8 1 1 0 1 1 1 0 Insulin/IGF/Relaxin family Nop14 PF04147.12 EMR69330.1 - 0.4 8.9 11.9 0.53 8.4 11.9 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 EMR69330.1 - 0.53 9.4 0.9 0.7 9.1 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter M_domain PF12938.7 EMR69330.1 - 0.77 9.5 13.4 1.7 8.4 13.4 1.5 1 0 0 1 1 1 0 M domain of GW182 RR_TM4-6 PF06459.12 EMR69330.1 - 0.78 9.5 6.5 1.1 9.0 6.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 EMR69330.1 - 2.7 7.3 14.1 4.7 6.5 14.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Roughex PF06020.11 EMR69330.1 - 9.9 5.1 14.2 19 4.2 14.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Aldo_ket_red PF00248.21 EMR69331.1 - 3.6e-65 220.1 0.0 4.5e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bac_GDH PF05088.12 EMR69331.1 - 0.066 10.7 0.2 0.09 10.2 0.2 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF4847 PF16139.5 EMR69331.1 - 0.077 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4847) MoCF_biosynth PF00994.24 EMR69332.1 - 3.2e-48 163.0 4.3 1.8e-23 82.8 0.2 2.7 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EMR69332.1 - 5.4e-41 140.0 3.5 1.1e-40 139.0 3.5 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EMR69332.1 - 2.5e-14 53.2 0.3 8.5e-14 51.5 0.1 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 EMR69332.1 - 0.95 8.8 9.5 1.5 8.2 9.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region EamA PF00892.20 EMR69333.1 - 0.034 14.3 1.1 0.039 14.1 1.1 1.1 1 0 0 1 1 1 0 EamA-like transporter family Nuc_sug_transp PF04142.15 EMR69333.1 - 0.22 10.7 0.0 0.26 10.4 0.0 1.3 1 1 0 1 1 1 0 Nucleotide-sugar transporter LRR_9 PF14580.6 EMR69334.1 - 1.9e-51 174.0 0.0 3.1e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EMR69334.1 - 3.8e-08 33.5 5.1 0.00011 22.5 4.6 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMR69334.1 - 8.8e-08 31.8 1.8 1.9e-07 30.7 1.8 1.6 1 0 0 1 1 1 1 Leucine rich repeat DUF4349 PF14257.6 EMR69334.1 - 0.019 14.4 2.5 0.034 13.6 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PspB PF06667.12 EMR69334.1 - 0.28 11.2 1.2 0.87 9.7 1.2 1.8 1 0 0 1 1 1 0 Phage shock protein B LRR_6 PF13516.6 EMR69334.1 - 1.8 8.8 3.5 88 3.5 0.4 3.9 5 0 0 5 5 5 0 Leucine Rich repeat CBFD_NFYB_HMF PF00808.23 EMR69335.1 - 2.6e-11 43.6 0.1 6.1e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMR69335.1 - 0.0027 18.1 0.1 0.0027 18.1 0.1 1.8 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Ribosomal_60s PF00428.19 EMR69335.1 - 0.0068 17.0 13.8 0.0068 17.0 13.8 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein IHABP4_N PF16174.5 EMR69335.1 - 0.67 10.5 5.8 4.2 7.9 6.0 2.0 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal NUC153 PF08159.12 EMR69336.1 - 2e-12 46.7 1.6 2e-12 46.7 1.6 3.4 3 0 0 3 3 3 2 NUC153 domain TFIIA_gamma_N PF02268.16 EMR69337.1 - 3.6e-24 84.5 0.2 5.2e-24 84.0 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EMR69337.1 - 2e-23 82.3 0.9 3.3e-23 81.5 0.9 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit GRP PF07172.11 EMR69339.1 - 0.00057 20.5 4.8 0.00086 20.0 4.3 1.6 1 1 0 1 1 1 1 Glycine rich protein family Shisa PF13908.6 EMR69339.1 - 0.0082 16.4 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SARAF PF06682.12 EMR69339.1 - 0.015 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Comm PF15957.5 EMR69339.1 - 0.017 15.5 0.2 0.058 13.7 0.1 1.8 1 1 1 2 2 2 0 Commissureless EphA2_TM PF14575.6 EMR69339.1 - 0.022 15.6 0.0 0.033 15.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF485 PF04341.12 EMR69339.1 - 0.03 14.3 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Prominin PF05478.11 EMR69339.1 - 0.037 12.0 0.0 0.041 11.9 0.0 1.0 1 0 0 1 1 1 0 Prominin DAG1 PF05454.11 EMR69339.1 - 0.065 12.6 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) MFS_Mycoplasma PF07672.13 EMR69339.1 - 0.079 12.2 0.0 0.097 11.9 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF4094 PF13334.6 EMR69339.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) m04gp34like PF12216.8 EMR69339.1 - 0.091 12.3 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Immune evasion protein DUF5305 PF17231.2 EMR69339.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 EMR69339.1 - 0.16 11.9 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family MIG-14_Wnt-bd PF06664.12 EMR69339.1 - 0.17 11.1 0.0 0.21 10.8 0.0 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion RIFIN PF02009.16 EMR69339.1 - 0.63 9.9 2.6 0.87 9.4 2.5 1.3 1 1 0 1 1 1 0 Rifin Cyclin_N PF00134.23 EMR69340.1 - 0.0022 17.7 0.0 0.013 15.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain MTES_1575 PF18741.1 EMR69340.1 - 0.21 11.8 0.2 20 5.5 0.0 2.3 2 0 0 2 2 2 0 REase_MTES_1575 Thioredoxin PF00085.20 EMR69341.1 - 1.6e-41 140.5 0.1 5.9e-23 80.8 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EMR69341.1 - 3.6e-10 40.1 0.0 0.00023 21.1 0.0 4.2 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMR69341.1 - 1.5e-06 28.4 0.6 0.064 13.6 0.0 3.9 4 1 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EMR69341.1 - 8.6e-05 22.9 0.8 0.25 11.8 0.1 3.5 2 1 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 EMR69341.1 - 0.00054 19.9 1.6 0.12 12.3 0.0 3.2 3 1 0 3 3 3 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EMR69341.1 - 0.00078 19.6 0.2 0.033 14.4 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EMR69341.1 - 0.019 15.0 0.2 0.23 11.5 0.0 2.9 4 0 0 4 4 4 0 Thioredoxin domain OST3_OST6 PF04756.13 EMR69341.1 - 0.045 13.1 0.0 2.8 7.2 0.0 2.6 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family HyaE PF07449.11 EMR69341.1 - 0.081 12.9 0.0 14 5.7 0.0 3.1 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 EMR69341.1 - 0.3 11.2 6.0 0.61 10.2 0.2 3.2 4 0 0 4 4 4 0 Thioredoxin TraF PF13728.6 EMR69341.1 - 0.44 10.3 4.6 0.25 11.2 0.1 2.6 2 2 2 4 4 4 0 F plasmid transfer operon protein PLDc_2 PF13091.6 EMR69342.1 - 3.2e-16 59.4 0.0 1e-05 25.4 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EMR69342.1 - 1.4e-11 44.0 1.3 3.4e-05 23.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Ribosomal_S5_C PF03719.15 EMR69342.1 - 0.16 11.4 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Lactonase PF10282.9 EMR69343.1 - 8.2e-71 239.0 0.0 1e-70 238.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NifT PF06988.11 EMR69343.1 - 0.15 11.8 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 NifT/FixU protein SNF2_N PF00176.23 EMR69344.1 - 4.1e-50 170.5 1.0 7.7e-47 159.7 1.0 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR69344.1 - 3.5e-22 78.8 0.0 9.3e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EMR69344.1 - 5.3e-06 25.8 0.0 1.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Nucleo_P87 PF07267.11 EMR69344.1 - 6.4 5.5 11.0 10 4.9 11.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Voltage_CLC PF00654.20 EMR69345.1 - 1e-89 301.3 25.2 1e-89 301.3 25.2 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EMR69345.1 - 2.9e-10 40.4 0.2 4.9e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF3246 PF11596.8 EMR69346.1 - 0.032 13.7 2.5 0.039 13.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Importin_rep_4 PF18808.1 EMR69346.1 - 0.044 14.1 1.3 0.072 13.4 1.3 1.3 1 0 0 1 1 1 0 Importin repeat DUF3245 PF11595.8 EMR69346.1 - 0.16 12.4 0.7 0.26 11.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Methyltransf_2 PF00891.18 EMR69347.1 - 4e-24 85.1 0.0 9.4e-24 83.9 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EMR69347.1 - 0.022 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_4 PF02390.17 EMR69347.1 - 0.09 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.6 EMR69347.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pox_Ag35 PF03286.14 EMR69348.1 - 0.0032 17.3 1.3 0.0032 17.3 1.3 2.5 2 1 1 3 3 3 1 Pox virus Ag35 surface protein PBP1_TM PF14812.6 EMR69348.1 - 6.2 7.3 8.2 1.4 9.3 1.6 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ParA PF10609.9 EMR69349.1 - 1.8e-78 263.4 1.3 2.7e-76 256.3 1.3 2.1 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Pkinase PF00069.25 EMR69350.1 - 6.4e-12 45.4 0.0 9.4e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EMR69350.1 - 5.2e-05 22.9 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EMR69350.1 - 5.4e-05 23.2 0.1 7.8e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EMR69350.1 - 7.6e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMR69350.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMR69350.1 - 0.04 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EMR69350.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Spherulin4 PF12138.8 EMR69351.1 - 9.3e-36 123.7 0.0 1.2e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 T5orf172 PF10544.9 EMR69352.1 - 7.4e-15 55.4 0.4 4e-14 53.0 0.0 2.5 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 EMR69352.1 - 4.1e-08 33.8 1.0 7.4e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 NOA36 PF06524.12 EMR69352.1 - 8.4 5.6 10.6 27 4.0 10.6 1.8 1 0 0 1 1 1 0 NOA36 protein Thymidylate_kin PF02223.17 EMR69353.1 - 7.2e-42 143.2 0.0 2.4e-41 141.5 0.0 1.7 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 EMR69353.1 - 0.00057 20.2 0.0 0.001 19.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain SAM_decarbox PF01536.16 EMR69354.1 - 2e-130 434.9 0.0 5.7e-130 433.5 0.0 1.7 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase K_channel_TID PF07941.11 EMR69354.1 - 3.3 8.2 8.4 5.5 7.5 1.5 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PTR2 PF00854.21 EMR69355.1 - 5.7e-74 249.3 13.9 9.8e-74 248.5 13.8 1.4 1 1 0 1 1 1 1 POT family DUF2721 PF11026.8 EMR69355.1 - 0.082 12.8 0.2 0.082 12.8 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Hce2 PF14856.6 EMR69356.1 - 0.084 13.2 0.1 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor RTA1 PF04479.13 EMR69357.1 - 1.1e-57 195.0 10.7 1.1e-57 195.0 10.7 2.0 1 1 1 2 2 2 2 RTA1 like protein Lactonase PF10282.9 EMR69359.1 - 3.4e-22 79.2 2.6 4.4e-20 72.2 3.2 2.2 1 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EMR69359.1 - 0.0011 18.6 0.4 0.015 14.9 0.1 2.5 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Tannase PF07519.11 EMR69360.1 - 3.5e-55 187.8 0.7 4.3e-55 187.5 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 EMR69360.1 - 0.072 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 EMR69362.1 - 7.1e-19 68.1 0.0 1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMR69362.1 - 3.8e-10 39.6 0.0 6.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EMR69362.1 - 4.7e-05 24.5 0.0 0.0001 23.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Histone PF00125.24 EMR69364.1 - 4.7e-19 69.1 0.0 6.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EMR69364.1 - 1e-12 47.6 0.1 2.5e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EMR69364.1 - 2.9e-05 24.3 0.0 4.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RSN1_7TM PF02714.15 EMR69365.1 - 2.7e-70 236.8 13.1 2.3e-69 233.8 13.1 2.1 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EMR69365.1 - 1.5e-24 87.2 0.0 2.2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EMR69365.1 - 3.4e-23 81.6 0.1 6.1e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_TM PF13967.6 EMR69365.1 - 2.3e-09 37.2 0.0 7e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport SmpA_OmlA PF04355.13 EMR69365.1 - 0.037 13.8 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 SmpA / OmlA family SsgA PF04686.12 EMR69365.1 - 0.097 12.7 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Streptomyces sporulation and cell division protein, SsgA 4HBT PF03061.22 EMR69366.1 - 9e-11 42.0 0.1 1.4e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EMR69366.1 - 0.01 16.1 0.1 0.02 15.2 0.1 1.5 1 0 0 1 1 1 0 Thioesterase-like superfamily Hce2 PF14856.6 EMR69367.1 - 5.7e-17 61.9 0.5 7.9e-17 61.4 0.0 1.4 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor Tannase PF07519.11 EMR69369.1 - 7.3e-24 84.5 0.0 7.9e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Fungal_trans PF04082.18 EMR69370.1 - 6e-18 64.8 0.1 8.7e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pentapeptide PF00805.22 EMR69371.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Sulfatase PF00884.23 EMR69372.1 - 4.1e-44 151.2 0.7 4.8e-42 144.4 0.0 2.5 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 EMR69372.1 - 4.8e-06 26.4 0.2 0.00034 20.3 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EMR69372.1 - 2.7e-05 24.4 0.7 4.7e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 EMR69372.1 - 0.1 13.3 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4712 PF15830.5 EMR69372.1 - 0.23 11.1 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) PHO4 PF01384.20 EMR69373.1 - 4e-83 279.3 9.3 4.5e-83 279.1 9.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family NAD_binding_8 PF13450.6 EMR69374.1 - 3.9e-10 39.8 0.1 8.4e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR69374.1 - 5.3e-08 32.6 1.0 9e-08 31.9 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EMR69374.1 - 4.9e-07 29.4 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EMR69374.1 - 5.6e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR69374.1 - 9.7e-05 21.6 1.6 0.00015 21.0 1.6 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMR69374.1 - 0.00012 20.9 0.4 0.00021 20.1 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EMR69374.1 - 0.00015 21.5 2.2 0.00044 19.9 1.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR69374.1 - 0.00023 21.6 0.4 0.00065 20.2 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR69374.1 - 0.00029 20.2 0.0 0.00074 18.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR69374.1 - 0.00034 19.9 0.1 0.0009 18.6 0.1 1.6 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EMR69374.1 - 0.049 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EMR69374.1 - 0.06 12.6 0.4 0.12 11.6 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EMR69374.1 - 0.065 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 EMR69374.1 - 0.13 11.3 0.4 0.21 10.7 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_N PF08240.12 EMR69375.1 - 7.1e-07 29.1 0.0 2.1e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR69375.1 - 0.00024 21.1 0.2 0.00064 19.7 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acylphosphatase PF00708.18 EMR69375.1 - 0.025 15.0 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Acylphosphatase adh_short PF00106.25 EMR69375.1 - 0.028 13.9 0.1 0.045 13.2 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Striatin PF08232.12 EMR69376.1 - 9.9e-43 146.4 4.9 9.9e-43 146.4 4.9 1.8 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 EMR69376.1 - 7.9e-23 80.3 18.4 2.9e-05 24.7 0.3 7.1 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR69376.1 - 0.00023 21.4 0.1 0.56 10.5 0.0 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ADH_N_2 PF16884.5 EMR69376.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase CALCOCO1 PF07888.11 EMR69376.1 - 0.052 12.4 6.3 0.08 11.8 6.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cytochrom_D1 PF02239.16 EMR69376.1 - 0.06 11.9 0.0 0.21 10.1 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EMR69376.1 - 0.22 10.5 0.0 0.58 9.1 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lebercilin PF15619.6 EMR69376.1 - 0.78 9.4 5.8 1.6 8.3 5.8 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4482 PF14818.6 EMR69376.1 - 5.6 7.8 11.6 0.36 11.7 4.9 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) R3H PF01424.22 EMR69377.1 - 2.1e-10 40.4 0.4 6.4e-10 38.9 0.4 1.8 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EMR69377.1 - 7.3e-05 22.5 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 EMR69378.1 - 4e-19 68.8 10.8 4e-19 68.8 10.8 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR69378.1 - 2.4e-07 30.0 8.3 7e-07 28.5 8.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EMR69378.1 - 0.0072 14.7 0.6 0.011 14.0 0.6 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kinesin PF00225.23 EMR69379.1 - 4.8e-93 311.7 0.0 4.8e-93 311.7 0.0 3.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EMR69379.1 - 8e-20 71.3 0.0 5.3e-16 58.9 0.0 3.9 3 0 0 3 3 3 2 Microtubule binding DegQ PF08181.11 EMR69379.1 - 5.3 7.2 7.0 24 5.1 0.5 4.4 3 0 0 3 3 3 0 DegQ (SacQ) family Aldo_ket_red PF00248.21 EMR69381.1 - 9.2e-74 248.3 0.0 1e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rep-A_N PF04057.12 EMR69382.1 - 0.015 15.4 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain DUF3433 PF11915.8 EMR69383.1 - 4.9e-34 116.7 12.6 1.8e-21 76.4 4.8 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF2457 PF10446.9 EMR69383.1 - 0.31 10.1 12.7 0.43 9.7 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 EMR69383.1 - 0.79 9.1 12.3 1.1 8.6 12.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EMR69383.1 - 1.1 7.3 10.3 1.5 6.9 10.3 1.0 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.11 EMR69383.1 - 9.2 5.9 17.7 14 5.3 17.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DJ-1_PfpI PF01965.24 EMR69384.1 - 5.5e-13 49.0 0.0 9.9e-13 48.2 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family E2R135 PF11570.8 EMR69385.1 - 0.058 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 SlyX PF04102.12 EMR69385.1 - 0.26 11.9 2.1 0.42 11.3 1.0 1.9 2 0 0 2 2 2 0 SlyX Rib_5-P_isom_A PF06026.14 EMR69386.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) FA_hydroxylase PF04116.13 EMR69387.1 - 0.01 16.1 4.2 0.01 16.1 4.2 2.0 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily adh_short PF00106.25 EMR69388.1 - 5.5e-24 84.7 0.4 2.9e-22 79.1 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69388.1 - 8.4e-16 58.2 0.5 1.7e-14 54.0 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR69388.1 - 4.3e-10 39.8 0.1 6.8e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR69388.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMR69388.1 - 0.013 15.0 0.1 0.045 13.2 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CUE PF02845.16 EMR69388.1 - 0.16 11.7 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 CUE domain Romo1 PF10247.9 EMR69389.1 - 0.0033 17.7 0.7 3.5 8.1 0.0 2.3 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 DUF1689 PF07954.11 EMR69389.1 - 0.0069 16.8 0.0 0.0088 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) SNARE_assoc PF09335.11 EMR69389.1 - 0.037 14.5 0.7 0.34 11.4 0.1 2.0 2 0 0 2 2 2 0 SNARE associated Golgi protein Fungal_trans PF04082.18 EMR69390.1 - 3.9e-09 35.9 0.0 6.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.18 EMR69391.1 - 1.2e-07 31.3 0.0 1.4e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain NAD_binding_10 PF13460.6 EMR69392.1 - 1.6e-08 34.7 0.0 2.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR69392.1 - 7.3e-07 29.0 0.0 1.6e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 EMR69392.1 - 0.002 17.8 1.6 0.0041 16.7 0.2 2.1 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR69392.1 - 0.012 15.1 0.0 0.064 12.7 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMR69392.1 - 0.084 12.3 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase FAD_binding_4 PF01565.23 EMR69394.1 - 8.1e-29 100.1 1.5 1.6e-28 99.2 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR69394.1 - 3.3e-07 30.3 0.6 6.9e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Amidohydro_1 PF01979.20 EMR69395.1 - 1.1e-18 67.7 0.0 4.3e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR69395.1 - 1.5e-13 51.0 0.1 1.1e-06 28.4 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Piwi PF02171.17 EMR69397.1 - 4.4e-60 203.5 0.0 6.3e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EMR69397.1 - 3.2e-11 42.7 0.0 8e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EMR69397.1 - 0.051 13.4 0.1 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 PAZ domain Porphobil_deam PF01379.20 EMR69398.1 - 4.5e-72 241.8 0.1 7.4e-72 241.1 0.0 1.4 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EMR69398.1 - 5.1e-17 62.0 0.1 1.2e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain V-set_CD47 PF08204.11 EMR69398.1 - 0.055 13.5 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain adh_short PF00106.25 EMR69399.1 - 6.9e-22 77.9 0.0 5.4e-17 61.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69399.1 - 1.7e-10 40.9 0.0 3.4e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR69399.1 - 0.06 12.8 0.2 0.17 11.3 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR69399.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.8 EMR69399.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Rota_VP2 PF05087.12 EMR69399.1 - 0.17 10.0 0.1 0.22 9.6 0.1 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein CDP-OH_P_transf PF01066.21 EMR69400.1 - 1.2e-12 48.4 0.3 1.2e-12 48.4 0.3 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.24 EMR69401.1 - 3e-100 334.5 0.0 3.4e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family adh_short_C2 PF13561.6 EMR69402.1 - 9.8e-31 107.1 0.3 1.6e-30 106.4 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR69402.1 - 9.8e-22 77.4 0.0 1.5e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EMR69403.1 - 2.7e-15 56.8 0.5 1.2e-14 54.6 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMR69403.1 - 5.1e-14 52.4 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR69403.1 - 2e-05 24.2 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMR69403.1 - 0.0007 18.8 0.3 0.0021 17.3 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EMR69403.1 - 0.0076 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EMR69403.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EMR69403.1 - 0.026 15.0 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 EMR69403.1 - 0.037 14.7 0.3 0.083 13.6 0.3 1.6 1 0 0 1 1 1 0 CoA binding domain ApbA PF02558.16 EMR69403.1 - 0.055 13.1 0.1 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA KR PF08659.10 EMR69403.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 EMR69403.1 - 0.1 11.6 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain EthD PF07110.11 EMR69404.1 - 2.4e-12 47.9 0.0 3.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.16 EMR69405.1 - 4.9e-40 137.5 56.6 2.3e-35 122.2 35.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MCR_alpha PF02249.17 EMR69405.1 - 0.11 13.0 0.1 0.27 11.7 0.1 1.6 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain UcrQ PF02939.16 EMR69406.1 - 0.082 12.8 2.7 0.14 12.1 0.1 2.6 3 1 0 3 3 3 0 UcrQ family Sigma_reg_N PF13800.6 EMR69406.1 - 3.2 8.1 6.2 17 5.8 0.2 3.5 4 0 0 4 4 4 0 Sigma factor regulator N-terminal MFS_1 PF07690.16 EMR69408.1 - 3.5e-26 92.0 69.0 3.4e-22 78.9 36.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Polyketide_cyc2 PF10604.9 EMR69409.1 - 0.013 15.8 0.2 0.032 14.5 0.2 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EMR69409.1 - 0.12 12.6 0.1 0.5 10.6 0.1 2.0 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport adh_short PF00106.25 EMR69410.1 - 5.3e-33 114.1 0.0 7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69410.1 - 1.9e-22 80.0 0.0 2.4e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EMR69410.1 - 3.1e-09 36.6 0.0 8.6e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EMR69410.1 - 3.4e-06 27.1 0.0 7.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMR69410.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EMR69410.1 - 0.027 14.0 0.1 0.064 12.8 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 EMR69410.1 - 0.05 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Peptidase_S8 PF00082.22 EMR69411.1 - 6.1e-25 88.1 2.0 7.5e-25 87.8 2.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR69411.1 - 2.4e-07 31.3 0.0 4.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 zf-RING_11 PF17123.5 EMR69412.1 - 3.6e-07 29.8 0.1 5.7e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EMR69412.1 - 2.1e-05 24.7 0.2 3.4e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMR69412.1 - 0.0023 17.7 0.2 0.0036 17.1 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMR69412.1 - 0.011 15.6 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR69412.1 - 0.039 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EMR69412.1 - 0.049 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.6 EMR69412.1 - 0.15 12.0 0.7 0.27 11.2 0.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 4HBT_3 PF13622.6 EMR69413.1 - 5.3e-37 128.4 0.0 6.3e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily CLTH PF10607.9 EMR69414.1 - 3.4e-32 111.4 0.0 6e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EMR69414.1 - 1.7e-06 27.9 0.3 3.2e-06 27.0 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EMR69414.1 - 0.00019 20.9 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 EMR69414.1 - 0.00049 20.4 0.2 0.00087 19.6 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EMR69414.1 - 0.0023 17.9 0.1 0.004 17.1 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EMR69414.1 - 0.0037 17.1 0.2 0.007 16.2 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMR69414.1 - 0.01 15.7 0.5 0.021 14.7 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMR69414.1 - 0.015 15.1 0.4 0.03 14.2 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EMR69414.1 - 0.049 13.5 0.5 0.089 12.6 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CK2S PF15011.6 EMR69414.1 - 0.054 13.4 0.5 0.25 11.2 0.4 2.0 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF3377 PF11857.8 EMR69415.1 - 0.85 9.6 8.3 12 5.9 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3377) PPP4R2 PF09184.11 EMR69416.1 - 1e-09 38.5 0.5 3.4e-09 36.7 0.0 1.7 1 1 1 2 2 2 1 PPP4R2 DUF16 PF01519.16 EMR69418.1 - 0.098 13.2 1.0 0.7 10.4 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF2959 PF11172.8 EMR69418.1 - 0.11 12.7 6.8 0.22 11.7 1.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) Syntaxin-6_N PF09177.11 EMR69418.1 - 0.12 12.9 1.0 1.5 9.4 0.5 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EMR69418.1 - 0.27 11.3 1.4 0.6 10.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MbeD_MobD PF04899.12 EMR69418.1 - 0.59 10.3 6.0 3.9 7.7 5.9 2.3 1 1 0 1 1 1 0 MbeD/MobD like Spc7 PF08317.11 EMR69418.1 - 1.3 7.8 5.5 0.32 9.8 1.7 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Abhydrolase_1 PF00561.20 EMR69419.1 - 1.9e-19 70.3 0.0 5.5e-19 68.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR69419.1 - 1e-11 44.6 0.0 5.2e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR69419.1 - 1.2e-10 42.4 0.0 1.5e-10 42.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family TruB_C PF09142.11 EMR69420.1 - 0.063 13.1 1.4 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal GLEYA PF10528.9 EMR69421.1 - 8.1e-15 55.0 1.6 8.1e-15 55.0 1.6 2.0 2 1 0 2 2 2 1 GLEYA domain LETM1 PF07766.13 EMR69422.1 - 6.2e-102 340.5 0.2 6.2e-102 340.5 0.2 1.8 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 EMR69422.1 - 0.00037 20.2 0.0 0.047 13.5 0.0 3.1 3 0 0 3 3 3 1 SAP domain PBP1_TM PF14812.6 EMR69423.1 - 0.00077 19.8 0.6 0.0015 18.9 0.6 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Pro_isomerase PF00160.21 EMR69424.1 - 7.6e-47 159.5 0.1 8.6e-47 159.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4813 PF16072.5 EMR69425.1 - 1.7 8.2 9.6 0.18 11.5 1.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4813) ANAPC1 PF12859.7 EMR69426.1 - 5.4e-30 104.6 0.8 5.4e-30 104.6 0.8 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 Pyr_redox_2 PF07992.14 EMR69429.1 - 2.6e-30 105.7 0.1 1.1e-27 97.0 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR69429.1 - 5.2e-13 49.4 0.9 6.6e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR69429.1 - 1.1e-06 28.0 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMR69429.1 - 2.3e-05 23.8 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR69429.1 - 0.0019 17.8 1.1 0.17 11.4 0.0 3.4 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR69429.1 - 0.0036 17.3 0.3 16 5.5 0.1 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding Trp_ring PF18669.1 EMR69429.1 - 0.02 15.0 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain ApbA PF02558.16 EMR69429.1 - 0.032 13.9 0.1 0.16 11.6 0.0 2.3 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ribosomal_L10 PF00466.20 EMR69429.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L10 Trp_halogenase PF04820.14 EMR69429.1 - 0.11 11.3 0.0 0.52 9.1 0.1 1.9 1 1 1 2 2 2 0 Tryptophan halogenase p450 PF00067.22 EMR69430.1 - 0.031 13.0 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Methyltransf_2 PF00891.18 EMR69431.1 - 4.8e-25 88.1 0.0 6.9e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EMR69431.1 - 0.00074 20.2 0.0 0.0014 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR69431.1 - 0.019 15.7 0.0 0.036 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EMR69431.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_3_C PF01915.22 EMR69432.1 - 1.2e-47 162.5 0.0 2.1e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR69432.1 - 2.4e-36 125.7 0.0 3.8e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR69432.1 - 1.8e-25 88.8 0.1 3.5e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 EMR69432.1 - 0.12 12.6 0.2 8.6 6.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF11 Clathrin PF00637.20 EMR69433.1 - 6.8e-25 87.6 0.6 1.6e-22 79.9 0.0 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.9 EMR69433.1 - 0.00061 20.1 0.1 0.01 16.1 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.6 EMR69433.1 - 0.068 13.1 2.8 0.076 13.0 0.4 2.0 2 0 0 2 2 2 0 zinc-RING finger domain DNA_pol_phi PF04931.13 EMR69433.1 - 0.14 10.2 25.5 0.35 8.9 25.5 1.7 1 0 0 1 1 1 0 DNA polymerase phi TPR_7 PF13176.6 EMR69433.1 - 0.51 10.5 2.7 4.9 7.4 0.3 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Acyltransferase PF01553.21 EMR69434.1 - 4.4e-33 113.8 0.0 6.6e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.21 EMR69434.1 - 0.024 14.6 0.0 0.057 13.4 0.0 1.6 2 0 0 2 2 2 0 Endoribonuclease L-PSP Aminotran_1_2 PF00155.21 EMR69435.1 - 8.1e-82 275.3 0.0 1e-81 275.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMR69435.1 - 2.1e-05 23.2 0.0 3.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMR69435.1 - 2.5e-05 23.4 0.0 5.4e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMR69435.1 - 0.0036 16.7 0.3 0.007 15.7 0.3 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4680 PF15730.5 EMR69435.1 - 0.11 12.8 0.2 0.22 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) DUF3405 PF11885.8 EMR69435.1 - 0.14 10.7 0.1 0.21 10.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Isochorismatase PF00857.20 EMR69436.1 - 2.2e-09 37.7 2.1 7.5e-09 36.0 2.1 1.8 1 1 0 1 1 1 1 Isochorismatase family ACAS_N PF16177.5 EMR69438.1 - 0.01 15.7 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Bac_luciferase PF00296.20 EMR69439.1 - 4.3e-69 233.3 0.1 5.2e-69 233.1 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase LrgB PF04172.16 EMR69440.1 - 2.8e-39 134.9 1.4 2.8e-39 134.9 1.4 2.0 2 0 0 2 2 2 1 LrgB-like family Pex14_N PF04695.13 EMR69440.1 - 0.24 12.1 2.3 0.46 11.1 2.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_3 PF07859.13 EMR69441.1 - 1.7e-49 168.6 0.7 2.3e-49 168.1 0.7 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR69441.1 - 1.8e-05 23.8 0.8 3.8e-05 22.8 0.8 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EMR69441.1 - 5.3e-05 22.8 0.1 0.012 15.1 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EMR69441.1 - 0.00014 21.4 0.4 0.00039 20.0 0.1 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase_phd PF10503.9 EMR69441.1 - 0.032 13.7 0.8 0.032 13.7 0.8 2.4 3 0 0 3 3 3 0 Esterase PHB depolymerase AXE1 PF05448.12 EMR69441.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HEV_ORF1 PF02444.16 EMR69441.1 - 0.45 11.1 3.6 0.25 11.9 0.7 2.0 1 1 1 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) Peptidase_S51 PF03575.17 EMR69442.1 - 1.5e-14 54.1 0.0 1.8e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 Lysozyme_like PF13702.6 EMR69443.1 - 0.00012 21.8 1.9 0.00024 20.9 1.9 1.4 1 1 0 1 1 1 1 Lysozyme-like SLT PF01464.20 EMR69443.1 - 0.042 13.5 0.3 0.13 11.9 0.3 1.8 1 1 0 1 1 1 0 Transglycosylase SLT domain DUF3926 PF13080.6 EMR69443.1 - 0.12 12.3 0.2 0.31 11.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) MFS_5 PF05631.14 EMR69444.1 - 4.9e-63 213.2 7.6 6.8e-63 212.7 7.6 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EMR69444.1 - 6.1e-20 71.4 20.4 6.1e-20 71.4 20.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AA_permease_2 PF13520.6 EMR69445.1 - 3.3e-12 46.0 27.2 3.5e-12 45.9 14.8 2.5 1 1 1 2 2 2 2 Amino acid permease Cellulase PF00150.18 EMR69446.1 - 5.1e-21 75.3 0.0 6.9e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 EMR69446.1 - 1.7e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 EMR69446.1 - 0.0017 17.5 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 EMR69446.1 - 0.0029 17.0 0.0 0.0065 15.9 0.0 1.5 2 0 0 2 2 2 1 Beta-galactosidase Transp_inhibit PF18791.1 EMR69446.1 - 0.41 10.2 3.2 0.46 10.0 1.4 2.0 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain Acyl-CoA_dh_1 PF00441.24 EMR69447.1 - 1.9e-17 63.8 4.1 3.7e-17 62.9 4.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMR69447.1 - 4.5e-07 30.0 0.0 7.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMR69447.1 - 1.9e-06 28.5 0.1 4.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMR69447.1 - 0.0019 18.5 5.1 0.0019 18.5 5.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_24 PF13578.6 EMR69448.1 - 1.4e-05 26.1 0.0 2.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain APG17 PF04108.12 EMR69449.1 - 0.0054 15.9 0.1 0.007 15.5 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 SesA PF17107.5 EMR69449.1 - 0.041 14.1 1.2 0.15 12.3 1.2 2.0 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Baculo_PEP_C PF04513.12 EMR69449.1 - 0.082 12.9 2.5 0.23 11.5 1.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 EMR69449.1 - 0.098 11.2 0.3 0.12 10.9 0.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A MFS_1 PF07690.16 EMR69450.1 - 5.8e-20 71.5 22.9 6.9e-20 71.3 22.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4407 PF14362.6 EMR69451.1 - 0.082 12.2 1.3 0.098 12.0 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2407_C PF13373.6 EMR69451.1 - 0.23 11.6 2.6 0.31 11.2 2.6 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain AAA_11 PF13086.6 EMR69451.1 - 0.33 10.7 3.2 0.42 10.3 3.2 1.1 1 0 0 1 1 1 0 AAA domain PBP1_TM PF14812.6 EMR69451.1 - 0.63 10.5 11.0 1.4 9.4 11.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal bZIP_2 PF07716.15 EMR69451.1 - 0.97 9.6 8.9 0.51 10.5 2.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper RRN3 PF05327.11 EMR69451.1 - 2 6.9 5.7 2 6.9 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EMR69451.1 - 2 6.6 8.4 2.1 6.6 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein ASFV_J13L PF05568.11 EMR69452.1 - 0.013 15.2 5.0 0.013 15.2 5.0 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein Acyl_transf_1 PF00698.21 EMR69453.1 - 2.6e-40 138.9 0.0 5e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR69453.1 - 5.1e-37 126.5 0.0 3.6e-36 123.7 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR69453.1 - 1.5e-18 67.3 0.4 2.6e-16 60.1 0.1 2.7 2 1 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ketoacyl-synt PF00109.26 EMR69453.1 - 2.1e-18 66.8 0.0 9.5e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain H_PPase PF03030.16 EMR69453.1 - 0.1 11.2 0.2 0.15 10.7 0.2 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF915 PF06028.11 EMR69453.1 - 0.2 10.9 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) SAC3_GANP PF03399.16 EMR69454.1 - 1.9e-24 86.6 5.4 2.3e-22 79.7 5.4 2.3 1 1 0 1 1 1 1 SAC3/GANP family COX5A PF02284.16 EMR69454.1 - 0.09 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Abhydrolase_6 PF12697.7 EMR69455.1 - 4.2e-18 66.8 1.6 5e-18 66.5 1.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR69455.1 - 0.00058 19.2 0.0 0.7 9.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF900 PF05990.12 EMR69455.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Med14 PF08638.11 EMR69456.1 - 1.2e-65 220.5 0.0 1.2e-65 220.5 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 DAG_kinase_N PF14513.6 EMR69456.1 - 1.6 8.9 7.6 3.5 7.8 7.6 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Presenilin PF01080.17 EMR69456.1 - 3.1 6.5 9.9 4.8 5.8 9.9 1.1 1 0 0 1 1 1 0 Presenilin API5 PF05918.11 EMR69456.1 - 3.5 6.3 12.8 5.6 5.6 12.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ALMT PF11744.8 EMR69456.1 - 7.9 5.2 7.1 13 4.5 7.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CorA PF01544.18 EMR69457.1 - 4e-43 147.8 1.1 1e-20 74.3 0.5 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein TIC20 PF16166.5 EMR69457.1 - 0.019 14.8 0.9 0.068 12.9 0.1 2.0 2 0 0 2 2 2 0 Chloroplast import apparatus Tic20-like sCache_3_2 PF17203.4 EMR69457.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 Band_7 PF01145.25 EMR69458.1 - 8e-23 81.3 2.2 1.3e-22 80.6 2.2 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S8 PF00082.22 EMR69459.1 - 5.7e-46 157.1 2.0 8.5e-46 156.6 2.0 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EMR69459.1 - 9.8e-07 29.5 0.0 6.7e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Fn3-like domain Inhibitor_I9 PF05922.16 EMR69459.1 - 0.0067 17.1 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 PA PF02225.22 EMR69459.1 - 0.0082 16.1 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 PA domain Asparaginase_C PF17763.1 EMR69459.1 - 0.07 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain HTH_ABP1_N PF18107.1 EMR69460.1 - 6.3e-25 86.7 4.3 1.6e-24 85.4 4.3 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 EMR69460.1 - 9.2e-16 57.6 0.8 1.3e-14 54.0 0.1 2.7 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain DUF434 PF04256.12 EMR69460.1 - 0.17 11.6 0.8 0.48 10.1 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF434) SH3_1 PF00018.28 EMR69461.1 - 4.5e-27 93.4 0.0 5.8e-13 48.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EMR69461.1 - 6e-18 64.4 0.3 1.8e-08 34.1 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 EMR69461.1 - 2.7e-14 53.1 0.0 5.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EMR69461.1 - 6.5e-11 41.7 0.0 1.3e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 EMR69461.1 - 5.9e-09 35.7 0.1 1e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 PB1 domain ubiquitin PF00240.23 EMR69461.1 - 0.0024 17.6 0.1 0.0048 16.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EMR69461.1 - 0.041 13.7 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glyco_tranf_2_5 PF13712.6 EMR69461.1 - 0.18 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family Elongin_A PF06881.11 EMR69462.1 - 8.6e-27 93.7 0.0 8.6e-27 93.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Slu7 PF11708.8 EMR69462.1 - 0.51 10.1 5.3 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DUF5624 PF18538.1 EMR69464.1 - 4e-47 159.5 0.0 6.5e-47 158.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) EPTP PF03736.17 EMR69464.1 - 2.2e-40 136.4 5.2 1.6e-08 34.4 0.1 6.8 7 0 0 7 7 7 6 EPTP domain EAP30 PF04157.16 EMR69465.1 - 9e-46 156.1 0.1 1.1e-45 155.8 0.1 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4197 PF13852.6 EMR69465.1 - 0.043 13.5 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) Ion_trans PF00520.31 EMR69466.1 - 2.9e-06 26.7 20.6 2.9e-06 26.7 20.6 1.7 1 1 1 2 2 2 1 Ion transport protein PKD_channel PF08016.12 EMR69466.1 - 0.0014 17.4 13.2 0.022 13.5 1.9 2.1 1 1 1 2 2 2 2 Polycystin cation channel PNTB_4TM PF12769.7 EMR69466.1 - 0.014 15.8 0.2 0.047 14.1 0.2 1.9 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Oxidored_q4 PF00507.19 EMR69466.1 - 0.017 15.3 1.7 0.017 15.3 1.7 2.3 1 1 2 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 PROL5-SMR PF15621.6 EMR69466.1 - 6.7 7.3 10.9 7.1 7.2 6.5 2.4 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Rad21_Rec8_N PF04825.13 EMR69467.1 - 1.5e-37 128.1 0.0 2.6e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EMR69467.1 - 8.5e-08 31.4 0.1 1.7e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Cation_ATPase_C PF00689.21 EMR69468.1 - 9.2e-45 152.6 0.2 1.7e-44 151.7 0.2 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EMR69468.1 - 1.1e-21 77.2 7.9 4.8e-13 49.0 0.1 3.1 2 1 1 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 EMR69468.1 - 2.4e-21 77.0 0.0 2.9e-20 73.5 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMR69468.1 - 1.4e-12 47.5 0.0 3.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMR69468.1 - 0.00081 19.2 1.1 0.0083 15.9 1.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Thymidylat_synt PF00303.19 EMR69469.1 - 7.6e-105 349.8 0.0 8.9e-105 349.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF4834 PF16118.5 EMR69469.1 - 0.13 13.3 0.5 0.21 12.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 EMR69469.1 - 0.2 11.4 0.0 0.58 9.9 0.0 1.6 2 0 0 2 2 2 0 Connexin Spt20 PF12090.8 EMR69469.1 - 0.65 9.6 5.0 1.1 8.9 5.0 1.3 1 0 0 1 1 1 0 Spt20 family His_Phos_2 PF00328.22 EMR69470.1 - 1e-24 87.6 0.0 1.4e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CSTF2_hinge PF14327.6 EMR69471.1 - 1.8e-32 111.6 2.1 1.8e-32 111.6 2.1 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EMR69471.1 - 4.6e-20 71.2 0.0 7.5e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EMR69471.1 - 6.7e-11 41.6 7.0 6.7e-11 41.6 7.0 3.4 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EMR69471.1 - 0.054 13.6 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Spo7_2_N PF15407.6 EMR69471.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 Abhydrolase_1 PF00561.20 EMR69472.1 - 3e-18 66.4 0.0 2e-16 60.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR69472.1 - 4.2e-15 56.9 0.4 5.1e-15 56.7 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR69472.1 - 2.1e-09 37.0 0.0 3.9e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMR69472.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain ubiquitin PF00240.23 EMR69473.1 - 1.2e-26 92.3 0.2 1.4e-26 92.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EMR69473.1 - 1.5e-14 53.6 0.2 1.7e-14 53.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMR69473.1 - 0.00029 21.2 0.0 0.00058 20.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EMR69473.1 - 0.00047 20.0 0.0 0.00061 19.7 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMR69473.1 - 0.12 12.5 0.1 0.36 10.9 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EMR69473.1 - 0.16 12.0 0.3 2.6 8.1 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain MFS_1 PF07690.16 EMR69474.1 - 2.6e-33 115.4 30.4 2.8e-30 105.4 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR69474.1 - 1.1e-10 41.0 12.4 1.1e-10 41.0 12.4 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMR69474.1 - 0.00068 18.2 5.0 0.00068 18.2 5.0 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PhzC-PhzF PF02567.16 EMR69475.1 - 1.7e-18 67.1 0.0 2.2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein KR PF08659.10 EMR69476.1 - 8.8e-52 175.6 0.2 1.6e-51 174.8 0.2 1.4 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EMR69476.1 - 6.1e-19 68.4 0.0 1e-16 61.1 0.0 2.3 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EMR69476.1 - 3e-16 60.7 0.0 8.1e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR69476.1 - 2.2e-13 50.3 0.4 2.4e-12 47.0 0.1 2.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR69476.1 - 2e-10 40.5 0.2 5.4e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 EMR69476.1 - 1.2e-09 38.4 0.1 1.3e-08 35.1 0.1 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EMR69476.1 - 9.8e-08 32.7 0.0 2.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR69476.1 - 0.005 17.5 0.0 0.016 15.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EMR69476.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_28 PF02636.17 EMR69476.1 - 0.02 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_33 PF10017.9 EMR69476.1 - 0.067 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_23 PF13489.6 EMR69476.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.22 EMR69478.1 - 4.2e-50 169.5 0.0 4.9e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR69478.1 - 6.3e-22 78.0 0.0 9.3e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR69478.1 - 3.6e-07 29.8 0.0 4.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EMR69478.1 - 0.0072 15.8 0.0 0.011 15.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EMR69478.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EMR69478.1 - 0.08 12.7 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EMR69478.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 EMR69478.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system CVNH PF08881.10 EMR69479.1 - 1.1e-29 103.1 0.1 1.7e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 CVNH domain LysM PF01476.20 EMR69479.1 - 2.8e-14 52.9 0.0 7.5e-14 51.5 0.0 1.7 2 0 0 2 2 2 1 LysM domain Rick_17kDa_Anti PF05433.15 EMR69479.1 - 0.00075 19.3 16.8 0.00075 19.3 16.8 2.2 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF697 PF05128.12 EMR69479.1 - 0.11 12.2 0.3 0.21 11.3 0.3 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF697) TraT PF05818.12 EMR69479.1 - 0.13 11.9 6.5 0.27 10.9 6.5 1.6 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Roughex PF06020.11 EMR69479.1 - 0.3 10.2 1.6 0.43 9.6 1.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF533 PF04391.12 EMR69479.1 - 0.36 10.4 5.7 0.049 13.2 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Aldo_ket_red PF00248.21 EMR69480.1 - 1.8e-73 247.3 0.0 2.1e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Far-17a_AIG1 PF04750.14 EMR69481.1 - 2.2e-06 27.1 11.2 2.2e-06 27.1 11.2 1.8 2 0 0 2 2 2 1 FAR-17a/AIG1-like protein MFS_1 PF07690.16 EMR69482.1 - 9.8e-20 70.8 11.7 1.3e-19 70.4 11.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Herpes_US9 PF06072.11 EMR69483.1 - 0.03 14.2 0.1 0.079 12.8 0.1 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 NST1 PF13945.6 EMR69485.1 - 5.4e-48 163.7 14.5 5.4e-48 163.7 14.5 4.2 3 2 1 4 4 4 1 Salt tolerance down-regulator Ribosomal_L9_N PF01281.19 EMR69486.1 - 2.7e-14 52.4 0.0 4.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EMR69486.1 - 0.015 15.8 0.1 0.051 14.1 0.1 1.8 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain MRP-L28 PF09812.9 EMR69487.1 - 1.1e-06 28.9 0.2 1.4e-06 28.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Aldedh PF00171.22 EMR69488.1 - 1.4e-154 515.1 0.0 1.5e-154 514.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ldh_2 PF02615.14 EMR69488.1 - 0.0099 15.1 0.1 0.028 13.6 0.0 1.6 2 0 0 2 2 2 1 Malate/L-lactate dehydrogenase Macro_2 PF14519.6 EMR69489.1 - 0.00033 20.1 0.0 0.0016 17.8 0.0 1.9 2 0 0 2 2 2 1 Macro-like domain DUF2510 PF10708.9 EMR69489.1 - 0.064 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) Macro PF01661.21 EMR69489.1 - 0.12 12.4 0.0 2.4 8.2 0.0 2.3 1 1 0 1 1 1 0 Macro domain FAD_binding_3 PF01494.19 EMR69490.1 - 1.3e-15 57.5 0.3 3.7e-15 56.0 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR69490.1 - 3.5e-10 39.6 1.0 3e-05 23.4 0.1 1.8 1 1 2 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR69490.1 - 2.6e-09 36.7 0.1 1.7e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EMR69490.1 - 9.1e-08 32.1 0.5 5.3e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EMR69490.1 - 1.8e-06 27.6 0.1 4e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR69490.1 - 2.6e-06 27.5 0.1 1e-05 25.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMR69490.1 - 4.9e-06 27.0 0.0 5.5e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMR69490.1 - 0.00019 20.8 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EMR69490.1 - 0.0014 17.4 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EMR69490.1 - 0.0019 17.5 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMR69490.1 - 0.0027 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EMR69490.1 - 0.021 13.9 0.2 0.035 13.1 0.2 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 EMR69490.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DPBB_1 PF03330.18 EMR69491.1 - 5.3e-09 36.2 0.3 1e-08 35.3 0.3 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EMR69491.1 - 0.0027 17.6 0.2 0.0047 16.8 0.2 1.5 1 0 0 1 1 1 1 Barwin family DAO PF01266.24 EMR69492.1 - 1.1e-23 84.4 0.0 1.7e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR69492.1 - 2.6e-06 27.5 0.1 9e-06 25.8 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR69492.1 - 1e-05 24.9 0.0 0.0041 16.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR69492.1 - 0.002 18.1 0.0 0.099 12.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMR69492.1 - 0.0085 16.6 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMR69492.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EMR69492.1 - 0.014 15.1 0.0 0.033 13.8 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EMR69492.1 - 0.024 14.8 0.0 0.1 12.7 0.0 2.0 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EMR69492.1 - 0.025 14.6 0.0 0.057 13.4 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 EMR69492.1 - 0.029 14.6 0.1 0.13 12.5 0.0 2.1 3 0 0 3 3 3 0 TrkA-N domain GIDA PF01134.22 EMR69492.1 - 0.058 12.5 0.0 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 EMR69492.1 - 0.081 12.5 0.0 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 EMR69492.1 - 0.17 10.6 0.0 2.1 6.9 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.6 EMR69492.1 - 0.18 10.9 0.0 0.68 9.0 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UPF0052 PF01933.18 EMR69492.1 - 0.2 10.9 0.0 0.92 8.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 AlaDh_PNT_C PF01262.21 EMR69492.1 - 0.23 10.7 0.1 0.67 9.2 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF829 PF05705.14 EMR69493.1 - 3.6e-36 125.3 0.2 4.8e-36 124.9 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Zn_clus PF00172.18 EMR69494.1 - 5.9e-10 39.1 8.8 1.1e-09 38.3 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Voldacs PF03517.13 EMR69494.1 - 0.016 15.3 0.1 0.038 14.1 0.1 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Mito_carr PF00153.27 EMR69495.1 - 1.8e-71 236.1 7.0 1.7e-25 88.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EMR69495.1 - 5.8e-20 71.5 7.0 1.3e-10 41.6 1.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EMR69495.1 - 5.9e-20 69.3 9.6 1.1e-06 27.7 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EMR69495.1 - 1.2e-17 62.2 9.7 0.00012 21.7 0.7 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EMR69495.1 - 2.7e-17 61.4 7.9 8.1e-06 25.1 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EMR69495.1 - 2.6e-09 36.8 5.6 2.1e-05 24.2 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EMR69495.1 - 1.8e-06 28.3 1.2 0.022 15.1 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EMR69495.1 - 0.15 12.0 6.6 5.3 7.1 0.1 3.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand PT-VENN PF04829.13 EMR69495.1 - 1.8 8.7 4.4 8 6.6 0.4 3.1 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Serine_protease PF18405.1 EMR69495.1 - 2.8 7.0 6.3 42 3.1 0.0 3.8 2 1 2 4 4 4 0 Gammaproteobacterial serine protease Cyclin_N PF00134.23 EMR69496.1 - 1.4e-11 44.2 0.5 3.1e-11 43.1 0.5 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EMR69496.1 - 0.0044 17.4 0.3 0.015 15.6 0.3 1.9 1 0 0 1 1 1 1 Cyclin C-terminal domain DUF3080 PF11279.8 EMR69496.1 - 0.031 13.5 6.6 0.026 13.8 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) TFIIB PF00382.19 EMR69496.1 - 0.059 13.4 0.2 0.059 13.4 0.2 1.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Turandot PF07240.11 EMR69496.1 - 0.082 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot WSC PF01822.19 EMR69498.1 - 4e-13 49.3 5.8 4e-13 49.3 5.8 2.3 3 0 0 3 3 3 1 WSC domain DUF3446 PF11928.8 EMR69498.1 - 0.49 10.7 13.7 1.7 9.0 3.4 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Sporozoite_P67 PF05642.11 EMR69498.1 - 4.5 5.2 11.0 2.6 6.0 3.0 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen GCS PF03074.16 EMR69499.1 - 1.6e-174 580.5 0.0 1.9e-174 580.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase K_channel_TID PF07941.11 EMR69499.1 - 1.4 9.4 4.0 0.38 11.2 0.5 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Het-C PF07217.11 EMR69501.1 - 5.3e-240 797.7 0.0 6.2e-240 797.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C HMG_box PF00505.19 EMR69502.1 - 1.9e-07 31.4 0.2 4.1e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR69502.1 - 6.7e-05 23.4 0.1 0.00022 21.7 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain Alpha_GJ PF03229.13 EMR69503.1 - 0.45 11.1 4.3 0.91 10.1 4.3 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J Aldedh PF00171.22 EMR69505.1 - 6.7e-100 334.8 0.7 3.2e-91 306.2 0.0 3.0 2 1 1 3 3 3 3 Aldehyde dehydrogenase family Amidohydro_1 PF01979.20 EMR69506.1 - 3.8e-75 253.3 0.2 3.8e-75 253.3 0.2 1.9 3 0 0 3 3 3 1 Amidohydrolase family Urease_alpha PF00449.20 EMR69506.1 - 5.6e-54 181.6 3.9 1.3e-53 180.4 3.9 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EMR69506.1 - 4.5e-40 135.6 0.0 9.6e-40 134.6 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 EMR69506.1 - 6.1e-40 135.5 0.2 2e-39 133.9 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EMR69506.1 - 3.6e-10 39.9 0.1 2.6e-06 27.2 0.0 2.4 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 EMR69506.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase RINT1_TIP1 PF04437.13 EMR69508.1 - 1.4e-179 598.2 0.0 2.1e-179 597.6 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 EMR69508.1 - 0.00012 22.6 4.0 0.00035 21.1 1.2 2.7 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) DHR10 PF18595.1 EMR69508.1 - 0.033 14.2 1.9 0.12 12.5 1.9 2.0 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Phage_GP20 PF06810.11 EMR69508.1 - 0.045 13.6 1.4 0.12 12.2 1.4 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 ADIP PF11559.8 EMR69508.1 - 0.18 11.9 3.0 0.44 10.6 3.0 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4164 PF13747.6 EMR69508.1 - 0.19 12.0 13.3 0.092 13.0 6.1 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF4164) SlyX PF04102.12 EMR69508.1 - 0.55 10.9 4.6 44 4.8 0.0 3.4 2 0 0 2 2 2 0 SlyX DUF4472 PF14739.6 EMR69508.1 - 0.58 10.9 3.4 0.84 10.4 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) Peptidase_S49_N PF08496.10 EMR69509.1 - 1.1 9.3 6.9 0.59 10.2 0.7 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Goodbye PF17109.5 EMR69509.1 - 2.4 8.6 6.5 5.9 7.4 0.0 2.7 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Afi1 PF07792.12 EMR69509.1 - 9.8 6.7 11.8 13 6.3 0.7 2.7 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking F-box PF00646.33 EMR69510.1 - 9.1e-05 22.2 0.8 0.0002 21.1 0.8 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMR69510.1 - 0.0062 16.4 1.9 0.0097 15.8 0.3 2.2 2 0 0 2 2 2 1 F-box-like FSH1 PF03959.13 EMR69512.1 - 1.2e-25 90.5 0.0 1.6e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EMR69512.1 - 0.013 15.4 1.5 0.029 14.2 0.4 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EMR69512.1 - 0.14 11.9 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Tannase PF07519.11 EMR69513.1 - 4.9e-94 315.9 0.0 6.1e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase AAA_13 PF13166.6 EMR69514.1 - 0.0031 16.2 11.2 0.0042 15.8 11.2 1.1 1 0 0 1 1 1 1 AAA domain DUF745 PF05335.13 EMR69514.1 - 0.036 13.8 12.8 0.6 9.8 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Fez1 PF06818.15 EMR69514.1 - 0.056 13.9 10.6 0.083 13.3 10.6 1.4 1 0 0 1 1 1 0 Fez1 YjcZ PF13990.6 EMR69514.1 - 0.076 12.4 4.4 0.11 11.9 4.4 1.3 1 0 0 1 1 1 0 YjcZ-like protein Fmp27_WPPW PF10359.9 EMR69514.1 - 0.077 11.8 7.3 0.1 11.5 7.3 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.11 EMR69514.1 - 0.17 10.7 13.5 0.26 10.1 13.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CHDCT2 PF08074.11 EMR69514.1 - 0.17 12.0 5.4 0.32 11.1 5.2 1.5 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain HIP1_clath_bdg PF16515.5 EMR69514.1 - 0.18 12.4 16.2 0.069 13.8 8.6 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4806 PF16064.5 EMR69514.1 - 0.45 10.8 2.3 1.1 9.6 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) V_ATPase_I PF01496.19 EMR69514.1 - 1.2 7.0 7.1 1.3 6.8 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 EMR69514.1 - 1.9 8.5 15.3 0.67 10.0 9.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 EMR69514.1 - 2.3 8.9 17.9 0.16 12.6 2.2 3.5 1 1 3 4 4 4 0 SlyX HetR_C PF18460.1 EMR69514.1 - 2.9 7.9 5.7 2.2 8.3 0.3 2.9 1 1 2 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Rsc14 PF08586.10 EMR69514.1 - 2.9 8.7 6.2 0.69 10.7 1.1 2.4 2 1 1 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit Syntaxin-6_N PF09177.11 EMR69514.1 - 6 7.5 16.4 26 5.5 14.0 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 EMR69514.1 - 6.1 7.4 16.2 46 4.5 16.1 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4404 PF14357.6 EMR69514.1 - 7.7 7.2 12.8 1.4 9.6 8.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Atg14 PF10186.9 EMR69514.1 - 8.1 5.4 16.9 24 3.9 16.9 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 EMR69514.1 - 9.2 6.3 17.3 1.1 9.4 3.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Hydrolase_4 PF12146.8 EMR69515.1 - 5.8e-15 55.2 0.0 2.8e-08 33.3 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR69515.1 - 1.1e-13 52.3 0.1 1.5e-13 51.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR69515.1 - 1.6e-12 47.7 0.0 3.3e-09 36.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Amidohydro_1 PF01979.20 EMR69516.1 - 3.9e-21 75.7 0.2 5.5e-21 75.2 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR69516.1 - 1.6e-08 34.4 1.7 3.7e-05 23.4 0.2 2.8 2 1 0 2 2 2 2 Amidohydrolase family DeoC PF01791.9 EMR69516.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 DeoC/LacD family aldolase NAD_binding_2 PF03446.15 EMR69517.1 - 2.6e-28 99.2 0.0 3.6e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMR69517.1 - 3e-08 33.9 0.0 6.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 EMR69517.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EMR69517.1 - 0.00024 21.6 0.0 0.00052 20.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMR69517.1 - 0.0028 17.7 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EMR69517.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA OCD_Mu_crystall PF02423.15 EMR69517.1 - 0.023 13.6 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.18 EMR69517.1 - 0.043 14.1 0.1 3.3 8.0 0.0 2.7 2 1 0 2 2 2 0 TrkA-N domain GFO_IDH_MocA PF01408.22 EMR69517.1 - 0.056 14.3 0.0 0.087 13.7 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Amino_oxidase PF01593.24 EMR69518.1 - 7.1e-08 32.2 0.0 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR69518.1 - 1.3e-06 28.5 0.2 2.9e-06 27.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR69518.1 - 8.6e-05 21.9 0.5 0.00038 19.8 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR69518.1 - 0.0001 22.3 1.0 0.12 12.3 0.2 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 EMR69518.1 - 0.00055 19.6 3.0 0.0018 17.9 0.9 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMR69518.1 - 0.0009 18.6 0.5 0.008 15.5 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EMR69518.1 - 0.0027 16.6 0.1 0.0037 16.2 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 EMR69518.1 - 0.0038 16.4 0.2 0.0045 16.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EMR69518.1 - 0.0072 16.9 0.2 0.064 13.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR69518.1 - 0.01 15.1 0.0 0.095 11.9 0.0 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR69518.1 - 0.023 13.9 0.3 0.039 13.2 0.2 1.4 1 1 0 1 1 1 0 Thi4 family GIDA PF01134.22 EMR69518.1 - 0.068 12.2 0.2 0.12 11.4 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EMR69518.1 - 0.083 11.6 0.3 0.13 10.9 0.2 1.4 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EMR69518.1 - 0.13 11.6 1.4 0.32 10.3 1.5 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1264 PF06884.11 EMR69519.1 - 2e-52 177.3 0.0 2.4e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) p450 PF00067.22 EMR69520.1 - 3.7e-47 161.1 0.0 7.8e-47 160.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Brix PF04427.18 EMR69521.1 - 3.7e-40 138.1 0.3 5.2e-40 137.6 0.3 1.2 1 0 0 1 1 1 1 Brix domain CFEM PF05730.11 EMR69522.1 - 6.1e-11 42.3 8.5 9.6e-11 41.6 8.5 1.3 1 0 0 1 1 1 1 CFEM domain Cytochrom_B561 PF03188.16 EMR69522.1 - 0.1 12.7 2.0 1.3 9.1 0.4 2.5 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 NnrU PF07298.11 EMR69522.1 - 0.18 11.3 9.9 2.6 7.5 0.6 3.2 1 1 2 3 3 3 0 NnrU protein DUF4714 PF15833.5 EMR69522.1 - 0.9 9.5 3.5 0.54 10.2 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4714) adh_short PF00106.25 EMR69523.1 - 6e-85 283.6 10.6 7.6e-44 149.5 0.6 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69523.1 - 5.4e-66 222.5 4.4 1.8e-33 116.1 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EMR69523.1 - 1.3e-30 105.5 0.0 3.5e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EMR69523.1 - 2.8e-29 102.3 3.4 6.5e-16 58.8 0.9 3.0 3 0 0 3 3 3 2 KR domain THF_DHG_CYH_C PF02882.19 EMR69523.1 - 0.0057 16.0 1.2 0.015 14.6 0.6 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IBR PF01485.21 EMR69524.1 - 4.1e-05 23.7 6.5 4.1e-05 23.7 6.5 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain Baculo_IE-1 PF05290.11 EMR69524.1 - 1.2 9.1 12.5 1 9.3 3.5 3.0 3 0 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) FAD_binding_4 PF01565.23 EMR69525.1 - 4.3e-25 88.1 3.1 7.4e-25 87.3 3.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR69525.1 - 3.1e-06 27.2 0.8 8.2e-06 25.8 0.3 2.0 2 0 0 2 2 2 1 Berberine and berberine like Glyco_hydro_88 PF07470.13 EMR69526.1 - 9.3e-63 212.4 4.8 1.1e-62 212.1 4.8 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EMR69526.1 - 0.016 13.8 0.3 0.02 13.4 0.3 1.1 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Mgm101p PF06420.12 EMR69527.1 - 3e-87 290.5 0.0 3.7e-87 290.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DBD_Tnp_Mut PF03108.15 EMR69527.1 - 0.079 13.0 0.7 0.15 12.0 0.7 1.4 1 0 0 1 1 1 0 MuDR family transposase BPL_N PF09825.9 EMR69529.1 - 2.5e-145 484.3 0.0 3.1e-145 484.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EMR69529.1 - 2.1e-22 79.4 0.0 3.5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EMR69529.1 - 0.00019 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain adh_short PF00106.25 EMR69530.1 - 1.4e-16 60.6 0.0 9.8e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR69530.1 - 0.00029 20.8 0.1 0.00038 20.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Rep_fac_C PF08542.11 EMR69531.1 - 3.3e-17 62.7 0.0 7.8e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EMR69531.1 - 6.3e-16 59.0 0.0 1.2e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EMR69531.1 - 7.6e-13 48.6 1.3 2.3e-12 47.0 0.0 2.3 2 1 0 2 2 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EMR69531.1 - 6e-08 32.8 0.0 1.4e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EMR69531.1 - 8.4e-07 28.9 0.1 2.5e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EMR69531.1 - 9.6e-07 29.1 0.1 3.3e-06 27.4 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_11 PF13086.6 EMR69531.1 - 9.4e-06 25.6 0.1 0.0001 22.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EMR69531.1 - 1.5e-05 25.2 0.1 8.7e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR69531.1 - 1.7e-05 25.2 0.0 9.3e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EMR69531.1 - 4e-05 23.4 0.0 8.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMR69531.1 - 5.2e-05 23.3 0.2 0.00016 21.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EMR69531.1 - 6.8e-05 22.1 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 EMR69531.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 EMR69531.1 - 0.00035 20.9 0.2 0.0011 19.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EMR69531.1 - 0.00036 20.4 0.1 0.0013 18.5 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMR69531.1 - 0.0004 20.2 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EMR69531.1 - 0.00066 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EMR69531.1 - 0.00095 18.7 0.5 1.2 8.5 0.0 2.5 1 1 0 2 2 2 2 PhoH-like protein Sigma54_activat PF00158.26 EMR69531.1 - 0.00095 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 EMR69531.1 - 0.0029 17.9 0.1 0.0061 16.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 EMR69531.1 - 0.0064 16.5 0.0 0.083 12.9 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 EMR69531.1 - 0.0071 15.8 0.0 0.052 13.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 EMR69531.1 - 0.0075 15.7 0.1 0.037 13.4 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EMR69531.1 - 0.0084 16.7 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EMR69531.1 - 0.013 15.3 0.2 0.15 11.9 0.1 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 EMR69531.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EMR69531.1 - 0.051 13.1 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 EMR69531.1 - 0.068 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain DUF2075 PF09848.9 EMR69531.1 - 0.07 12.4 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RrnaAD PF00398.20 EMR69531.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RNA_helicase PF00910.22 EMR69531.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EMR69531.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Thr_synth_N PF14821.6 EMR69532.1 - 0.047 13.9 0.1 15 5.9 0.0 2.3 2 0 0 2 2 2 0 Threonine synthase N terminus AT_hook PF02178.19 EMR69532.1 - 0.8 9.8 27.0 0.087 12.7 3.0 3.6 3 0 0 3 3 3 0 AT hook motif RFX5_DNA_bdg PF14621.6 EMR69532.1 - 4.7 6.9 10.4 0.76 9.5 1.3 2.3 1 1 1 2 2 2 0 RFX5 DNA-binding domain NAD_binding_8 PF13450.6 EMR69534.1 - 3.4e-14 52.8 0.0 4.4e-13 49.3 0.0 2.8 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EMR69534.1 - 1.2e-08 33.9 0.1 8.3e-08 31.1 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.24 EMR69534.1 - 2.5e-05 24.0 0.0 0.3 10.6 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR69534.1 - 0.00067 19.7 0.0 0.003 17.6 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMR69534.1 - 0.0017 17.6 0.0 0.3 10.3 0.0 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR69534.1 - 0.049 12.9 0.0 0.61 9.3 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR69534.1 - 0.13 11.4 0.0 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HET PF06985.11 EMR69535.1 - 3.3e-24 85.9 0.0 5.6e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4754 PF15946.5 EMR69536.1 - 0.19 12.0 1.5 0.42 10.9 0.0 2.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4754) DUF3659 PF12396.8 EMR69537.1 - 1.3e-178 579.1 133.5 2e-22 78.8 7.0 12.2 12 1 0 12 12 12 10 Protein of unknown function (DUF3659) GCV_T_C PF08669.11 EMR69537.1 - 0.00056 19.8 1.5 10 6.1 0.0 5.4 4 0 0 4 4 4 1 Glycine cleavage T-protein C-terminal barrel domain Apolipoprotein PF01442.18 EMR69537.1 - 0.0014 18.6 7.3 0.0014 18.6 7.3 2.9 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EMR69537.1 - 0.0039 17.3 7.1 0.0039 17.3 7.1 3.8 5 0 0 5 5 5 1 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.11 EMR69537.1 - 0.023 14.9 13.0 2.9 8.2 1.7 4.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 EMR69537.1 - 0.09 13.4 13.1 1.3 9.7 2.3 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.9 EMR69537.1 - 1.4 7.6 18.6 0.37 9.6 9.1 2.3 2 0 0 2 2 2 0 Mitochondrial inner membrane protein APC_u14 PF16635.5 EMR69538.1 - 1.7 9.2 8.4 0.88 10.1 4.9 2.3 2 1 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr Sugar_tr PF00083.24 EMR69539.1 - 3.7e-56 190.9 12.9 8.9e-56 189.6 12.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR69539.1 - 5.8e-09 35.3 17.7 5.8e-09 35.3 17.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PGAP1 PF07819.13 EMR69540.1 - 0.0024 17.6 0.0 0.0055 16.5 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EMR69540.1 - 0.013 16.1 1.1 0.021 15.5 0.4 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EMR69540.1 - 0.19 11.3 0.0 0.42 10.1 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase 2OG-FeII_Oxy_3 PF13640.6 EMR69541.1 - 2.2e-08 34.9 0.0 3.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_7 PF13508.7 EMR69542.1 - 1.7e-08 34.7 0.0 2.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR69542.1 - 4.2e-07 30.0 0.0 5.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR69542.1 - 5e-06 26.7 0.0 5.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMR69542.1 - 9.7e-05 22.3 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Asparaginase_2 PF01112.18 EMR69543.1 - 2e-66 224.1 6.4 2.6e-66 223.8 6.4 1.0 1 0 0 1 1 1 1 Asparaginase TauD PF02668.16 EMR69544.1 - 1.4e-34 120.1 0.0 2e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sirohm_synth_C PF14823.6 EMR69544.1 - 0.093 12.4 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Glyco_hydro_43 PF04616.14 EMR69546.1 - 0.00025 20.5 0.1 0.0043 16.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 HTH_psq PF05225.16 EMR69547.1 - 9.6e-18 63.7 0.0 3.9e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.20 EMR69547.1 - 1.4e-06 28.5 0.2 1.3e-05 25.4 0.1 2.5 2 1 0 2 2 2 1 Transposase CENP-B_N PF04218.13 EMR69547.1 - 1.5e-05 24.5 0.0 0.012 15.2 0.0 2.5 2 0 0 2 2 2 2 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 EMR69547.1 - 0.00015 21.7 0.0 0.00064 19.7 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 EMR69547.1 - 0.0043 16.8 0.4 0.25 11.2 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 EMR69547.1 - 0.007 16.5 0.0 0.024 14.8 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 EMR69547.1 - 0.025 14.4 0.0 0.57 10.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_ParB PF17762.1 EMR69547.1 - 0.027 14.3 0.1 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 HTH domain found in ParB protein Sigma70_r4_2 PF08281.12 EMR69547.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 SpoIIID PF12116.8 EMR69547.1 - 0.11 12.6 0.0 4 7.6 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein D ANTAR PF03861.14 EMR69547.1 - 0.13 12.1 0.2 0.99 9.3 0.1 2.5 3 0 0 3 3 3 0 ANTAR domain Phage_portal PF04860.12 EMR69547.1 - 0.14 11.4 0.0 0.31 10.2 0.0 1.5 2 0 0 2 2 2 0 Phage portal protein HTH_7 PF02796.15 EMR69547.1 - 0.15 12.2 0.0 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Glyco_hydro_61 PF03443.14 EMR69548.1 - 4.9e-53 180.1 1.4 6.2e-53 179.8 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BAP PF06639.11 EMR69548.1 - 0.082 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) EthD PF07110.11 EMR69549.1 - 1.7e-14 54.7 1.2 2.4e-14 54.2 1.2 1.2 1 0 0 1 1 1 1 EthD domain Nicastrin PF05450.15 EMR69549.1 - 0.06 12.8 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Nicastrin DPPIV_N PF00930.21 EMR69550.1 - 5.7e-104 347.7 4.2 8e-104 347.2 4.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EMR69550.1 - 1.5e-39 135.7 1.0 2.4e-39 135.0 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EMR69550.1 - 0.00025 21.7 0.0 0.00055 20.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR69550.1 - 0.0027 17.4 0.1 0.0061 16.2 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_61 PF03443.14 EMR69551.1 - 9.6e-68 228.2 0.1 9.6e-68 228.2 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EMR69551.1 - 2.7e-12 46.4 10.3 7.6e-12 45.0 10.3 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain SOG2 PF10428.9 EMR69551.1 - 0.25 10.5 9.3 0.31 10.2 9.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TB2_DP1_HVA22 PF03134.19 EMR69552.1 - 2.8e-24 84.9 9.9 4.6e-24 84.1 9.9 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SUIM_assoc PF16619.5 EMR69552.1 - 0.0022 18.0 2.6 0.0022 18.0 2.6 2.7 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 EMR69552.1 - 8.2 5.1 6.7 16 4.1 6.7 1.4 1 0 0 1 1 1 0 Presenilin Transket_pyr PF02779.24 EMR69553.1 - 0.094 12.4 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain DUF1996 PF09362.10 EMR69554.1 - 4.3e-84 282.2 0.6 5.3e-84 281.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RNase_H PF00075.24 EMR69555.1 - 4.4e-13 49.6 0.1 6.8e-11 42.5 0.0 2.2 1 1 1 2 2 2 2 RNase H Goodbye PF17109.5 EMR69556.1 - 1.3e-22 80.5 0.2 5.4e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain TPR_12 PF13424.6 EMR69556.1 - 0.0023 18.2 0.9 0.023 15.0 1.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 EMR69556.1 - 0.0026 18.2 0.0 0.017 15.5 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain MPDZ_u10 PF16667.5 EMR69556.1 - 1.1 10.2 7.5 0.36 11.7 3.9 2.1 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein MAP17 PF15807.5 EMR69557.1 - 0.016 15.4 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 MRP-S31 PF15433.6 EMR69557.1 - 1.5 8.4 3.7 2.1 7.9 3.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF3659 PF12396.8 EMR69558.1 - 3.1e-18 65.4 11.0 4e-13 49.1 6.3 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3659) Lipase_GDSL_2 PF13472.6 EMR69559.1 - 2.2e-06 28.2 0.2 4.3e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR69559.1 - 0.028 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase FTZ PF03867.14 EMR69559.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Chal_sti_synt_C PF02797.15 EMR69560.1 - 1.8e-21 76.7 0.0 3.4e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EMR69560.1 - 5.2e-21 75.1 0.1 7.8e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 EMR69560.1 - 0.00033 20.1 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EMR69560.1 - 0.003 17.7 0.0 0.0098 16.0 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EMR69560.1 - 0.038 13.8 0.3 0.15 12.0 0.3 2.0 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thioredoxin_6 PF13848.6 EMR69561.1 - 3.9e-15 56.2 0.0 5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain OPT PF03169.15 EMR69562.1 - 2.5e-94 317.1 45.0 3.1e-94 316.8 45.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pam16 PF03656.13 EMR69563.1 - 3.6e-34 117.5 0.1 4.3e-34 117.3 0.1 1.0 1 0 0 1 1 1 1 Pam16 Hamartin PF04388.12 EMR69564.1 - 4.3 5.9 14.4 5 5.7 14.4 1.2 1 0 0 1 1 1 0 Hamartin protein DnaJ PF00226.31 EMR69565.1 - 1.1e-24 86.3 1.2 1.1e-24 86.3 1.2 2.0 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 EMR69565.1 - 3.5e-10 39.9 3.3 3.5e-10 39.9 3.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EMR69565.1 - 5.9e-08 33.0 4.2 0.0012 19.1 1.6 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EMR69565.1 - 5.1e-07 29.9 7.4 6.8e-07 29.5 2.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EMR69565.1 - 6.2e-05 23.5 4.7 0.12 13.3 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EMR69565.1 - 0.00017 21.8 7.1 0.16 12.5 0.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type RPT PF13446.6 EMR69565.1 - 0.014 15.3 0.0 0.28 11.1 0.0 2.9 2 1 0 2 2 2 0 A repeated domain in UCH-protein PSCyt3 PF07627.11 EMR69565.1 - 0.053 13.8 0.1 0.23 11.7 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) zf-LYAR PF08790.11 EMR69565.1 - 0.079 12.9 4.3 0.63 10.0 0.5 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 EMR69565.1 - 3.3 7.8 8.4 5.6 7.1 1.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger SR-25 PF10500.9 EMR69566.1 - 0.045 13.4 7.8 0.93 9.1 5.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CPSF100_C PF13299.6 EMR69566.1 - 0.29 11.3 1.6 0.57 10.4 1.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AP3D1 PF06375.11 EMR69566.1 - 3.4 7.9 10.7 29 4.8 0.0 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Pyr_redox_2 PF07992.14 EMR69567.1 - 3.6e-56 190.6 2.4 4.7e-56 190.2 2.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMR69567.1 - 4e-41 139.7 0.0 1.2e-40 138.1 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMR69567.1 - 3.4e-20 72.4 2.5 9.7e-20 70.9 0.9 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR69567.1 - 0.00021 21.5 0.5 0.019 15.2 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EMR69567.1 - 0.00099 18.4 0.2 0.0016 17.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 EMR69567.1 - 0.0014 17.8 0.0 0.96 8.5 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMR69567.1 - 0.0031 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMR69567.1 - 0.0052 16.1 1.1 0.013 14.8 0.5 1.9 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EMR69567.1 - 0.049 13.2 5.8 7.8 6.0 1.5 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Peptidase_C54 PF03416.19 EMR69568.1 - 5.1e-50 170.4 0.0 1.7e-42 145.7 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 SPX PF03105.19 EMR69569.1 - 8.2e-51 174.1 0.1 1.1e-50 173.7 0.1 1.2 1 0 0 1 1 1 1 SPX domain Cys_Met_Meta_PP PF01053.20 EMR69569.1 - 1.1e-31 109.8 0.0 1.7e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-C3HC4 PF00097.25 EMR69569.1 - 1.4e-08 34.5 5.4 3.4e-08 33.2 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMR69569.1 - 7.4e-07 28.9 7.4 1.6e-06 27.9 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR69569.1 - 1.1e-06 28.3 6.0 1.8e-06 27.7 5.3 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR69569.1 - 1.7e-06 27.9 4.9 4.4e-06 26.6 4.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EMR69569.1 - 4.9e-06 26.8 8.7 1.4e-05 25.4 8.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EMR69569.1 - 0.00045 20.3 7.5 0.00045 20.3 7.5 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMR69569.1 - 0.00048 20.0 6.4 0.0017 18.2 6.4 2.0 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EMR69569.1 - 0.018 14.9 7.2 0.079 12.8 7.1 2.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Aminotran_1_2 PF00155.21 EMR69569.1 - 0.054 12.7 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II zf-rbx1 PF12678.7 EMR69569.1 - 0.14 12.5 4.4 0.38 11.1 4.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EMR69569.1 - 0.41 10.6 2.1 1.1 9.1 2.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EMR69569.1 - 0.62 9.9 7.8 0.11 12.3 3.6 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Complex1_LYR PF05347.15 EMR69570.1 - 1.5e-10 41.0 1.5 2.3e-10 40.4 1.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 EMR69571.1 - 2.1e-21 75.3 3.1 3.8e-21 74.5 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EMR69571.1 - 6.7e-17 62.1 0.0 9.1e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EMR69571.1 - 9.8e-06 25.8 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 EMR69571.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 LcrG protein Histone PF00125.24 EMR69572.1 - 1.8e-21 76.8 2.5 2.3e-21 76.5 2.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EMR69572.1 - 4.1e-05 23.8 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EMR69572.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 EMR69572.1 - 0.023 14.3 0.1 0.054 13.1 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 EMR69574.1 - 2.3e-13 49.9 0.0 3.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EMR69574.1 - 3.2e-11 42.9 2.1 8.4e-11 41.6 2.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EMR69574.1 - 0.025 14.6 1.4 0.025 14.6 1.4 2.9 4 0 0 4 4 4 0 G-patch domain 2-oxoacid_dh PF00198.23 EMR69575.1 - 2.6e-80 269.2 0.2 5.2e-80 268.2 0.1 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMR69575.1 - 4e-19 68.2 3.2 8e-19 67.3 3.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 EMR69575.1 - 0.0011 19.6 0.9 0.78 10.5 0.1 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EMR69575.1 - 0.0049 16.7 0.7 0.013 15.3 0.2 1.9 1 1 1 2 2 2 1 Biotin-lipoyl like DUF3614 PF12267.8 EMR69575.1 - 0.068 13.7 0.0 0.25 11.8 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) DUF1387 PF07139.11 EMR69575.1 - 0.24 11.1 5.6 0.34 10.6 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Presenilin PF01080.17 EMR69575.1 - 1 8.1 3.9 1.4 7.6 3.9 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EMR69575.1 - 1.2 7.8 7.1 1.5 7.4 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2052 PF09747.9 EMR69575.1 - 2 8.5 7.8 3.4 7.7 7.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Acyl_transf_3 PF01757.22 EMR69576.1 - 0.034 13.2 0.0 0.046 12.8 0.0 1.3 1 1 0 1 1 1 0 Acyltransferase family AATase PF07247.12 EMR69577.1 - 1.6e-13 50.1 0.0 4e-13 48.7 0.0 1.5 2 0 0 2 2 2 1 Alcohol acetyltransferase Tri3 PF07428.11 EMR69577.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Peptidase_S58 PF03576.14 EMR69578.1 - 4.8e-115 384.2 0.1 5.5e-115 384.0 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S58 Chromo PF00385.24 EMR69579.1 - 6.3e-16 58.0 4.8 8.6e-09 35.2 0.9 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain CENP-N PF05238.13 EMR69579.1 - 0.063 12.6 0.9 0.08 12.2 0.9 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Fe-ADH PF00465.19 EMR69580.1 - 2.1e-103 345.9 0.0 2.6e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMR69580.1 - 2.4e-15 56.9 0.0 8.9e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 EMR69580.1 - 0.037 13.7 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein Glyco_hydro_61 PF03443.14 EMR69581.1 - 5.3e-55 186.5 0.0 6.7e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 EMR69582.1 - 7e-17 61.4 30.2 1.8e-08 33.7 11.4 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR69582.1 - 0.00015 20.8 2.3 0.00015 20.8 2.3 2.6 3 1 0 3 3 3 2 Sugar (and other) transporter SnoaL_2 PF12680.7 EMR69583.1 - 6.5e-06 26.7 0.0 9.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EMR69583.1 - 0.027 14.3 0.1 0.28 11.0 0.0 2.0 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase NTF2 PF02136.20 EMR69583.1 - 0.086 13.4 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF3429 PF11911.8 EMR69584.1 - 8.3e-45 152.6 10.5 1e-44 152.3 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF2568 PF10823.8 EMR69584.1 - 6.8 7.0 8.9 5.9 7.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2568) SHR-BD PF06650.12 EMR69585.1 - 1.7e-102 342.4 0.0 1.2e-96 323.3 0.0 2.8 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EMR69585.1 - 9.3e-93 310.0 16.9 6.9e-92 307.1 1.9 5.6 5 1 1 6 6 6 3 Repeating coiled region of VPS13 VPS13 PF16908.5 EMR69585.1 - 1.7e-87 293.1 1.2 9e-86 287.5 0.0 3.2 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EMR69585.1 - 4.9e-71 238.2 5.8 1.6e-67 226.8 0.4 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EMR69585.1 - 2.6e-39 133.9 0.0 8.9e-39 132.2 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EMR69585.1 - 1.3e-06 28.7 0.1 1.1e-05 25.7 0.0 2.6 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain DUF4050 PF13259.6 EMR69586.1 - 4.2e-48 164.1 0.0 4.2e-48 164.1 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) SDA1 PF05285.12 EMR69586.1 - 0.85 9.0 9.7 1.8 7.9 9.7 1.6 1 0 0 1 1 1 0 SDA1 Macoilin PF09726.9 EMR69586.1 - 6.8 5.1 10.0 0.094 11.3 2.6 1.6 2 0 0 2 2 2 0 Macoilin family Med7 PF05983.11 EMR69587.1 - 1e-64 218.2 0.2 1.2e-64 217.9 0.2 1.1 1 0 0 1 1 1 1 MED7 protein DUF848 PF05852.11 EMR69587.1 - 0.062 13.4 0.0 4.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Glyco_hydro_18 PF00704.28 EMR69588.1 - 2.9e-88 296.6 4.1 3.4e-88 296.4 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hira PF07569.11 EMR69589.1 - 9.6e-34 117.0 0.0 2.5e-33 115.7 0.0 1.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 EMR69589.1 - 1.9e-24 85.5 16.4 2.6e-05 24.9 0.0 7.5 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR69589.1 - 1.5e-14 54.0 0.0 0.0055 17.0 0.0 5.3 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EMR69589.1 - 3.4e-05 23.7 3.2 13 5.8 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EMR69589.1 - 0.0033 17.3 0.1 3.4 7.5 0.0 3.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EMR69589.1 - 0.039 12.0 0.1 0.23 9.4 0.0 2.1 2 1 1 3 3 3 0 IKI3 family MFS_1 PF07690.16 EMR69590.1 - 2.8e-23 82.4 31.7 2.8e-23 82.4 31.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 EMR69590.1 - 0.38 10.4 0.0 0.38 10.4 0.0 3.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4131) p450 PF00067.22 EMR69592.1 - 1.9e-05 23.7 0.0 1.9e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4934 PF16288.5 EMR69592.1 - 0.054 13.4 0.0 0.096 12.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4934) adh_short PF00106.25 EMR69593.1 - 6.4e-19 68.2 0.0 8.7e-16 57.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69593.1 - 1.6e-10 41.0 0.0 5.9e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR69593.1 - 2.2e-06 27.7 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_transf_15 PF01793.16 EMR69594.1 - 9.6e-98 327.4 8.9 1.4e-97 326.9 8.9 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DEAD PF00270.29 EMR69595.1 - 1.3e-42 145.6 0.0 5.2e-42 143.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR69595.1 - 1.4e-28 99.5 0.0 3.5e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR69595.1 - 5.6e-05 23.2 0.8 0.00015 21.8 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C2H2_jaz PF12171.8 EMR69596.1 - 0.0047 17.2 0.1 0.0047 17.2 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FAM76 PF16046.5 EMR69596.1 - 0.0081 15.5 6.9 0.012 14.9 1.9 2.2 2 0 0 2 2 2 1 FAM76 protein DUF3580 PF12117.8 EMR69596.1 - 0.014 15.6 5.6 0.032 14.5 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) OrsD PF12013.8 EMR69596.1 - 0.042 14.3 3.8 0.055 13.9 2.0 2.0 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1677 PF07911.13 EMR69596.1 - 0.051 14.0 0.5 0.13 12.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) zf-met PF12874.7 EMR69596.1 - 0.078 13.4 0.2 0.078 13.4 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EMR69596.1 - 0.22 11.9 3.4 0.4 11.1 3.4 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) dsRBD2 PF17842.1 EMR69596.1 - 0.25 11.5 2.9 2.3 8.4 0.4 2.3 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 CTU2 PF10288.9 EMR69596.1 - 4.9 7.4 12.0 0.072 13.3 2.8 2.4 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 FtsJ PF01728.19 EMR69597.1 - 2.7e-43 148.1 0.0 3.6e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF104 PF01954.16 EMR69597.1 - 0.0068 16.8 0.8 0.015 15.8 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF104 BCCT PF02028.17 EMR69598.1 - 0.0017 16.9 0.0 0.002 16.6 0.0 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter p450 PF00067.22 EMR69599.1 - 7.2e-56 189.8 1.3 6.1e-26 91.2 0.1 4.0 1 1 2 3 3 3 3 Cytochrome P450 Sortilin-Vps10 PF15902.5 EMR69601.1 - 5.5e-15 55.1 8.2 0.00034 19.5 0.0 5.8 4 2 1 5 5 5 5 Sortilin, neurotensin receptor 3, LAMTOR PF15454.6 EMR69601.1 - 1.3e-07 32.1 0.6 2.5e-07 31.2 0.6 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator BNR PF02012.20 EMR69601.1 - 1.4e-07 30.4 23.3 2.7 8.3 0.0 9.0 8 0 0 8 8 8 4 BNR/Asp-box repeat BNR_2 PF13088.6 EMR69601.1 - 9.4e-05 21.8 10.8 0.14 11.5 0.1 5.7 4 2 1 5 5 5 2 BNR repeat-like domain BNR_6 PF15899.5 EMR69601.1 - 0.005 16.8 10.6 23 5.4 0.0 7.5 8 0 0 8 8 8 1 BNR-Asp box repeat Kelch_4 PF13418.6 EMR69601.1 - 0.075 13.1 2.1 0.64 10.1 0.0 3.5 2 1 1 3 3 3 0 Galactose oxidase, central domain RNase_T PF00929.24 EMR69602.1 - 2.3e-07 31.5 0.0 1.4e-06 28.9 0.0 2.0 1 1 0 1 1 1 1 Exonuclease zf-C2H2_4 PF13894.6 EMR69602.1 - 5.6e-05 23.6 1.8 0.13 13.1 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMR69602.1 - 0.00016 21.6 5.3 0.029 14.4 0.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMR69602.1 - 0.00035 20.8 0.7 0.0013 19.0 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EMR69602.1 - 0.00061 20.1 3.4 0.039 14.4 0.8 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 EMR69602.1 - 0.003 17.9 1.6 0.37 11.3 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DNA_pol_A_exo1 PF01612.20 EMR69602.1 - 0.2 11.3 0.0 0.8 9.4 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease zf-C2HC_2 PF13913.6 EMR69602.1 - 0.58 10.1 3.4 2.8 7.9 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FA_desaturase PF00487.24 EMR69603.1 - 1.6e-31 110.0 21.6 2.2e-31 109.6 21.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase CDO_I PF05995.12 EMR69603.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I p450 PF00067.22 EMR69604.1 - 7.1e-26 91.0 0.0 8.4e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EMR69605.1 - 1.6e-20 73.4 0.1 1.2e-15 57.5 0.3 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69605.1 - 4.7e-11 42.7 0.2 6.6e-08 32.4 0.2 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR69605.1 - 1e-08 35.3 0.7 1.8e-08 34.5 0.7 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EMR69605.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ABC2_membrane PF01061.24 EMR69606.1 - 1.6e-74 249.9 50.9 1.4e-41 142.3 18.0 3.2 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EMR69606.1 - 1.2e-34 118.0 10.4 4.9e-29 100.1 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 EMR69606.1 - 9.9e-34 116.8 0.2 8.5e-16 58.7 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.6 EMR69606.1 - 1.3e-12 48.2 0.2 3.9e-12 46.6 0.2 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EMR69606.1 - 1.8e-10 40.5 52.4 1.6e-06 27.5 22.8 2.7 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 EMR69606.1 - 1.2e-06 29.0 0.1 0.0016 18.9 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EMR69606.1 - 1.2e-05 25.0 0.1 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMR69606.1 - 2.2e-05 24.4 0.1 5.3e-05 23.2 0.0 1.6 2 0 0 2 2 1 1 RsgA GTPase AAA_21 PF13304.6 EMR69606.1 - 6.3e-05 22.9 0.1 0.42 10.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EMR69606.1 - 0.00071 19.2 0.2 0.094 12.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EMR69606.1 - 0.0008 20.0 0.1 0.0046 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMR69606.1 - 0.00099 19.4 0.3 0.35 11.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EMR69606.1 - 0.0018 18.7 0.8 0.034 14.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EMR69606.1 - 0.0038 17.4 0.0 0.23 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMR69606.1 - 0.0066 16.2 0.1 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 EMR69606.1 - 0.0092 15.9 0.2 1.2 9.1 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 EMR69606.1 - 0.018 15.3 0.1 0.067 13.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMR69606.1 - 0.022 14.9 0.5 0.92 9.6 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SSE PF00437.20 EMR69606.1 - 0.025 13.7 0.0 3.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 EMR69606.1 - 0.034 13.9 0.1 0.6 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EMR69606.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase TsaE PF02367.17 EMR69606.1 - 0.051 13.6 0.4 0.85 9.6 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EMR69606.1 - 0.063 13.6 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EMR69606.1 - 0.077 12.7 0.0 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EMR69606.1 - 0.1 12.0 0.0 1.9 7.9 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 EMR69606.1 - 0.11 13.0 0.1 5 7.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EMR69606.1 - 0.17 11.2 0.2 20 4.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase PF06745.13 EMR69606.1 - 0.19 11.1 0.1 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 KaiC Septin PF00735.18 EMR69606.1 - 0.2 10.9 0.3 19 4.4 0.0 2.4 2 0 0 2 2 2 0 Septin GET2 PF08690.10 EMR69606.1 - 0.22 11.2 1.5 14 5.3 0.1 2.6 2 0 0 2 2 2 0 GET complex subunit GET2 Glyco_hydro_61 PF03443.14 EMR69607.1 - 9.1e-32 110.7 0.0 1.1e-31 110.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Nucleoside_tran PF01733.18 EMR69608.1 - 1.4e-16 60.8 9.7 1.3e-14 54.4 0.2 2.7 2 2 1 3 3 3 2 Nucleoside transporter DUF2145 PF09916.9 EMR69608.1 - 0.0099 15.6 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2145) TMEM132D_C PF15706.5 EMR69608.1 - 0.021 14.6 0.0 0.15 11.8 0.0 2.3 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term AA_permease PF00324.21 EMR69609.1 - 9.6e-99 331.1 42.3 1.2e-98 330.9 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR69609.1 - 1.3e-22 80.2 45.7 1.7e-22 79.9 45.7 1.1 1 0 0 1 1 1 1 Amino acid permease Ins_P5_2-kin PF06090.12 EMR69610.1 - 1e-36 127.1 0.0 2.5e-36 125.8 0.0 1.5 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase EspB_PE PF18625.1 EMR69610.1 - 0.029 14.8 0.4 0.071 13.6 0.4 1.7 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain Peptidase_C21 PF05381.12 EMR69610.1 - 0.082 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Tymovirus endopeptidase PRIMA1 PF16101.5 EMR69610.1 - 3.5 7.7 8.8 1.4 8.9 3.3 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EMR69610.1 - 10 5.5 8.0 1.9 7.9 3.1 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF3995 PF13160.6 EMR69611.1 - 0.4 11.1 14.5 0.12 12.7 2.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) Iso_dh PF00180.20 EMR69613.1 - 2.8e-83 280.0 0.0 3.1e-83 279.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 EMR69614.1 - 3.8e-37 128.0 31.0 3.8e-37 128.0 31.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR69614.1 - 2.3e-09 36.6 23.5 3.3e-09 36.1 23.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Phage_holin_5_2 PF16079.5 EMR69614.1 - 1 9.8 16.4 4.2 7.8 0.5 4.3 2 2 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V Pribosyltran PF00156.27 EMR69615.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DAO PF01266.24 EMR69616.1 - 7.4e-49 167.2 0.1 8.5e-49 167.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR69616.1 - 5.8e-07 29.1 0.0 0.00075 18.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR69616.1 - 1.4e-06 27.8 0.0 0.00054 19.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR69616.1 - 6.6e-06 26.2 0.2 0.0019 18.2 0.0 3.0 2 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMR69616.1 - 1.7e-05 25.0 0.0 4.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR69616.1 - 7.7e-05 21.9 0.1 0.045 12.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 EMR69616.1 - 0.00012 21.5 0.0 0.027 13.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EMR69616.1 - 0.00012 20.9 0.0 0.23 10.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 EMR69616.1 - 0.0007 18.9 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EMR69616.1 - 0.0025 16.9 0.1 0.03 13.4 0.0 2.5 2 1 1 3 3 3 1 Lycopene cyclase protein MCRA PF06100.11 EMR69616.1 - 0.023 13.5 0.0 0.057 12.2 0.0 1.5 2 0 0 2 2 2 0 MCRA family Trp_halogenase PF04820.14 EMR69616.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Abhydrolase_1 PF00561.20 EMR69618.1 - 2.5e-18 66.7 0.0 3.9e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR69618.1 - 3.3e-15 57.3 0.1 5.2e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EMR69618.1 - 3.6e-06 25.9 0.0 5.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 EMR69618.1 - 7.4e-05 22.1 0.0 0.00016 21.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EMR69618.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Polysacc_lyase PF14099.6 EMR69619.1 - 2e-06 27.8 0.3 2.9e-06 27.3 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide lyase Aminotran_3 PF00202.21 EMR69620.1 - 4.6e-116 387.8 0.0 5.2e-116 387.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Cupin_2 PF07883.11 EMR69621.1 - 1.4e-07 31.1 0.1 0.0078 15.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 EMR69621.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EMR69621.1 - 0.1 12.3 0.1 0.81 9.4 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Hydrolase PF00702.26 EMR69622.1 - 5.8e-06 26.7 0.0 8.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR69622.1 - 0.0016 18.5 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Peptidase_S64 PF08192.11 EMR69623.1 - 0.16 10.4 0.6 0.22 10.0 0.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 P5CR_dimer PF14748.6 EMR69624.1 - 2.1e-23 82.5 2.0 2.4e-23 82.4 0.1 2.0 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EMR69624.1 - 2.2e-10 41.0 0.9 8.1e-10 39.2 0.9 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EMR69624.1 - 0.00061 19.8 0.0 0.0015 18.5 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EMR69624.1 - 0.03 14.0 0.1 0.048 13.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EMR69624.1 - 0.071 13.0 0.2 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YEATS PF03366.16 EMR69626.1 - 2.1e-24 85.3 1.2 3.7e-23 81.3 1.2 2.2 1 1 0 1 1 1 1 YEATS family Aldedh PF00171.22 EMR69628.1 - 1e-159 532.0 0.1 1.1e-159 531.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMR69628.1 - 0.0036 16.8 0.0 0.34 10.3 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) TFB6 PF17110.5 EMR69629.1 - 0.036 13.8 0.3 0.068 12.9 0.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2277 PF10041.9 EMR69629.1 - 0.22 11.9 2.4 18 5.8 0.1 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) Aminotran_1_2 PF00155.21 EMR69631.1 - 3.7e-95 319.2 0.0 4.2e-95 319.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HAD PF12710.7 EMR69632.1 - 3.3e-11 44.0 4.0 1.3e-06 29.0 1.1 3.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMR69632.1 - 0.028 14.2 0.2 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR69632.1 - 0.028 14.7 0.0 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR69632.1 - 0.048 13.8 1.4 0.16 12.1 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 EMR69633.1 - 0.076 11.8 0.3 0.19 10.5 0.2 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain FA_desaturase PF00487.24 EMR69634.1 - 3.2e-18 66.5 11.8 3.2e-18 66.5 11.8 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EMR69634.1 - 3.4e-17 62.4 0.1 9.1e-17 61.0 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 EMR69635.1 - 1.7e-09 37.3 0.0 3.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR69635.1 - 0.0022 18.2 0.0 0.0063 16.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMR69635.1 - 0.079 12.9 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMR69635.1 - 0.11 11.7 0.1 1.4 8.1 0.0 2.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Asp_Glu_race PF01177.22 EMR69635.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase HI0933_like PF03486.14 EMR69635.1 - 0.22 10.2 0.1 0.5 9.0 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Asp_protease PF09668.10 EMR69636.1 - 5.2e-53 178.1 0.2 8.9e-53 177.3 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EMR69636.1 - 2.2e-20 73.0 0.3 6.5e-20 71.5 0.1 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EMR69636.1 - 1.9e-11 44.5 0.1 2.7e-10 40.7 0.1 2.6 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 EMR69636.1 - 2.5e-07 30.3 0.0 4.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EMR69636.1 - 1.3e-06 28.2 0.2 3.5e-06 26.8 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 EMR69636.1 - 1.5e-05 25.3 0.0 4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 EMR69636.1 - 0.00016 21.4 0.0 0.00034 20.4 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.8 EMR69636.1 - 0.073 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UBA_4 PF14555.6 EMR69636.1 - 0.078 12.8 0.1 0.078 12.8 0.1 1.9 2 0 0 2 2 2 0 UBA-like domain Methyltransf_8 PF05148.15 EMR69637.1 - 1.7e-56 191.5 0.0 1.4e-53 182.0 0.0 3.7 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EMR69637.1 - 5.2e-06 27.0 0.0 1.3e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR69637.1 - 7.5e-05 23.4 0.2 0.0019 18.9 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR69637.1 - 0.0069 16.2 0.1 1 9.2 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR69637.1 - 0.08 12.5 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EMR69637.1 - 0.092 12.7 0.0 0.092 12.7 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain MFS_1 PF07690.16 EMR69638.1 - 4.5e-06 25.8 4.1 5.8e-06 25.5 4.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR69638.1 - 0.001 18.1 1.3 0.0018 17.2 1.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter GCP_N_terminal PF17681.1 EMR69639.1 - 3.4e-64 217.4 0.0 6.4e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EMR69639.1 - 5.6e-60 203.4 1.4 5.6e-60 203.4 1.4 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 EMR69640.1 - 9.6e-57 191.5 0.2 1.2e-56 191.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMR69640.1 - 1.6e-12 46.9 0.0 3.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PI3_PI4_kinase PF00454.27 EMR69642.1 - 1.3e-42 146.3 0.0 2e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1729 PF08354.10 EMR69643.1 - 0.19 10.6 0.3 0.35 9.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) TFIIF_beta_N PF17683.1 EMR69644.1 - 3e-34 118.6 0.5 5.8e-34 117.7 0.5 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EMR69644.1 - 4.6e-25 87.5 1.2 7.8e-25 86.8 1.2 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain ResIII PF04851.15 EMR69645.1 - 5.4e-15 55.8 0.1 1.9e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMR69645.1 - 8.6e-10 39.0 0.0 1.3e-06 28.8 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EMR69645.1 - 3.2e-06 27.0 0.0 7.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EMR69645.1 - 0.0082 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 EMR69645.1 - 0.086 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 EMR69646.1 - 7.5e-72 241.9 0.0 1.2e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR69646.1 - 1.3e-13 51.2 0.0 5.6e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EMR69646.1 - 5e-06 26.4 1.9 1.2e-05 25.2 1.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EMR69646.1 - 6.6e-06 25.9 1.8 1.6e-05 24.6 1.8 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EMR69646.1 - 2.5e-05 24.1 2.1 5.4e-05 23.0 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR69646.1 - 0.00021 21.1 2.8 0.00065 19.5 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EMR69646.1 - 0.00041 20.2 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 EMR69646.1 - 0.00093 19.5 1.3 0.0025 18.1 1.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EMR69646.1 - 0.0023 17.9 0.6 0.0055 16.7 0.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMR69646.1 - 0.017 15.2 0.7 0.035 14.1 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ResIII PF04851.15 EMR69646.1 - 0.08 12.9 0.0 0.81 9.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EMR69646.1 - 0.12 12.2 5.3 0.06 13.2 2.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.11 EMR69646.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 GAGA factor zf-rbx1 PF12678.7 EMR69646.1 - 0.21 11.9 6.4 0.035 14.4 1.7 2.2 3 0 0 3 3 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EMR69646.1 - 0.46 10.7 2.9 1 9.6 2.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Serinc PF03348.15 EMR69647.1 - 2.6e-151 504.4 9.1 3.1e-151 504.1 9.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) AP3D1 PF06375.11 EMR69647.1 - 0.33 11.2 2.1 0.48 10.7 2.1 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Myb_DNA-binding PF00249.31 EMR69649.1 - 0.0024 18.0 0.0 0.0057 16.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 EMR69650.1 - 7.4e-32 109.2 2.9 1.5e-31 108.2 2.9 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM PF04433.17 EMR69650.1 - 1.2e-31 108.9 0.2 2.6e-31 107.8 0.2 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EMR69650.1 - 3.3e-09 36.8 0.1 6.3e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR69650.1 - 4.1e-06 26.9 0.5 9.2e-06 25.8 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EMR69650.1 - 0.032 14.4 0.2 0.077 13.2 0.2 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF4451 PF14616.6 EMR69650.1 - 0.11 12.8 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) DUF3439 PF11921.8 EMR69650.1 - 5.2 7.1 9.4 0.095 12.7 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) bZIP_1 PF00170.21 EMR69651.1 - 7.6e-08 32.3 18.0 8.2e-08 32.2 14.3 2.6 1 1 2 3 3 3 2 bZIP transcription factor DUF737 PF05300.11 EMR69651.1 - 1.7e-05 25.3 8.1 0.00024 21.5 3.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF737) bZIP_Maf PF03131.17 EMR69651.1 - 5.9e-05 23.5 12.8 0.00013 22.4 12.2 1.9 1 1 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EMR69651.1 - 0.00088 19.3 11.4 0.00088 19.3 11.4 2.8 1 1 2 3 3 3 1 Basic region leucine zipper IL11 PF07400.11 EMR69651.1 - 0.07 12.8 5.0 0.24 11.0 5.0 2.0 1 0 0 1 1 1 0 Interleukin 11 Adeno_E3 PF06040.11 EMR69651.1 - 0.089 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 protein FapA PF03961.13 EMR69651.1 - 0.75 8.3 9.5 1.1 7.8 9.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ARD PF03079.14 EMR69651.1 - 3.3 7.9 6.9 6.9 6.8 6.9 1.5 1 0 0 1 1 1 0 ARD/ARD' family DivIC PF04977.15 EMR69651.1 - 3.9 7.3 13.8 3.8 7.3 0.7 3.1 2 1 1 3 3 3 0 Septum formation initiator ETF PF01012.21 EMR69652.1 - 2.7e-45 154.5 1.1 4.4e-45 153.8 1.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EMR69652.1 - 1.2e-33 115.0 0.4 2.5e-33 114.0 0.4 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Sel1 PF08238.12 EMR69653.1 - 1.8e-10 41.1 0.5 2.6e-05 24.8 0.0 3.0 3 0 0 3 3 3 2 Sel1 repeat TraC PF07820.12 EMR69653.1 - 0.031 14.6 1.2 0.066 13.5 0.0 2.2 2 0 0 2 2 2 0 TraC-like protein YqeY PF09424.10 EMR69654.1 - 8e-22 77.9 1.5 9.9e-22 77.6 1.5 1.1 1 0 0 1 1 1 1 Yqey-like protein Mito_carr PF00153.27 EMR69655.1 - 7.8e-60 198.8 2.3 6.7e-23 80.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1d PF00750.19 EMR69656.1 - 7.4e-69 232.3 0.0 1.3e-68 231.6 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EMR69656.1 - 8.8e-11 42.0 0.0 2.1e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 DALR anticodon binding domain Nse4_C PF08743.10 EMR69657.1 - 8.7e-32 109.3 0.0 1.8e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EMR69657.1 - 1.5e-18 66.6 0.3 4.4e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4618 PF15397.6 EMR69657.1 - 0.1 12.0 0.1 0.1 12.0 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2961 PF11175.8 EMR69657.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) zf-P11 PF03854.14 EMR69659.1 - 0.0074 15.9 3.5 0.011 15.3 3.5 1.2 1 0 0 1 1 1 1 P-11 zinc finger PI3_PI4_kinase PF00454.27 EMR69660.1 - 1.2e-36 126.8 0.0 1.2e-31 110.4 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FRQ PF09421.10 EMR69661.1 - 0.042 11.9 3.3 0.049 11.7 3.3 1.0 1 0 0 1 1 1 0 Frequency clock protein TSC22 PF01166.18 EMR69662.1 - 0.023 15.0 37.7 0.097 13.0 0.4 11.6 9 3 4 13 13 13 0 TSC-22/dip/bun family Spc7 PF08317.11 EMR69662.1 - 0.88 8.4 177.5 0.006 15.5 20.5 9.5 2 2 7 9 9 9 0 Spc7 kinetochore protein GAS PF13851.6 EMR69662.1 - 1.2 8.4 175.0 0.41 10.0 24.9 9.2 3 2 6 9 9 9 0 Growth-arrest specific micro-tubule binding GRP PF07172.11 EMR69662.1 - 1.9 9.2 18.0 12 6.6 18.0 2.5 1 0 0 1 1 1 0 Glycine rich protein family TMF_TATA_bd PF12325.8 EMR69662.1 - 4.6 7.5 126.5 0.022 15.0 4.7 12.2 3 2 10 14 14 14 0 TATA element modulatory factor 1 TATA binding Fasciclin PF02469.22 EMR69663.1 - 3.4e-48 163.1 0.1 4.1e-27 94.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain ATP-synt_C PF00137.21 EMR69664.1 - 2.9e-25 88.4 33.7 1.7e-16 60.3 13.4 2.2 2 0 0 2 2 2 2 ATP synthase subunit C ELP6 PF09807.9 EMR69664.1 - 0.05 13.0 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 CARD_2 PF16739.5 EMR69665.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Caspase recruitment domain CNH PF00780.22 EMR69667.1 - 3.9e-79 266.1 0.0 1.9e-78 263.8 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EMR69667.1 - 2.8e-38 131.1 0.0 5.3e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EMR69667.1 - 2.2e-35 122.5 0.1 8.1e-35 120.7 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.21 EMR69667.1 - 1.4e-15 57.1 0.0 3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KN_motif PF12075.8 EMR69667.1 - 0.075 12.9 0.1 0.35 10.7 0.1 2.1 1 0 0 1 1 1 0 KN motif PH PF00169.29 EMR69667.1 - 0.12 12.9 0.0 15 6.2 0.0 3.1 3 0 0 3 3 3 0 PH domain DUF4336 PF14234.6 EMR69669.1 - 4.6e-15 55.6 0.0 1.9e-09 37.2 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4336) p450 PF00067.22 EMR69670.1 - 2.4e-40 138.7 0.0 2.8e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EMR69671.1 - 8.3e-62 208.1 0.1 5.2e-42 143.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69671.1 - 1.1e-44 152.8 0.1 2.8e-26 92.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR69671.1 - 4.1e-15 56.2 0.6 6.8e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EMR69671.1 - 0.00011 21.7 0.5 0.061 12.8 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 EMR69671.1 - 0.039 14.0 3.6 0.23 11.5 0.5 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR69671.1 - 0.043 13.1 0.1 0.043 13.1 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain YAcAr PF10686.9 EMR69671.1 - 0.069 13.1 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Polysacc_synt_2 PF02719.15 EMR69671.1 - 0.089 11.9 0.2 0.82 8.7 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 EMR69673.1 - 6.2e-32 111.0 0.0 9.9e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMR69673.1 - 7.4e-20 71.4 0.1 1.2e-19 70.8 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EMR69673.1 - 0.00031 21.3 0.0 0.0007 20.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 EMR69673.1 - 0.002 17.1 0.0 0.0039 16.2 0.0 1.5 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family p450 PF00067.22 EMR69674.1 - 1.3e-43 149.4 0.0 3.3e-27 95.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Bac_luciferase PF00296.20 EMR69675.1 - 3.8e-57 194.1 0.5 4.8e-57 193.8 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 EMR69675.1 - 0.0073 16.1 0.0 0.65 9.7 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase adh_short PF00106.25 EMR69676.1 - 8.2e-35 120.0 0.0 1e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69676.1 - 3e-27 95.7 0.0 3.8e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR69676.1 - 0.00052 20.0 0.4 0.0015 18.5 0.4 1.8 1 1 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 EMR69677.1 - 2.7e-32 112.4 0.0 5.4e-32 111.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMR69677.1 - 2.1e-08 33.3 0.5 1e-07 31.1 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 EMR69677.1 - 3.3e-08 33.0 0.0 4.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMR69677.1 - 7.4e-07 28.7 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EMR69677.1 - 1.8e-06 27.4 0.1 5.3e-06 25.9 0.1 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR69677.1 - 2.2e-06 27.5 0.3 2.5e-05 24.1 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EMR69677.1 - 6.8e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR69677.1 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR69677.1 - 1.6e-05 25.0 0.0 3.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EMR69677.1 - 0.00054 19.2 0.0 0.00083 18.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EMR69677.1 - 0.00086 18.5 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 EMR69677.1 - 0.0011 19.4 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 EMR69677.1 - 0.0025 18.3 0.4 0.034 14.7 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GerD PF17898.1 EMR69677.1 - 0.055 13.4 0.2 0.099 12.6 0.2 1.3 1 0 0 1 1 1 0 Spore germination GerD central core domain Amino_oxidase PF01593.24 EMR69677.1 - 0.067 12.5 0.0 0.44 9.8 0.0 2.2 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EMR69677.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 EMR69677.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EMR69677.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 EMR69678.1 - 5.9e-17 62.2 0.0 1.5e-15 57.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR69678.1 - 4.1e-13 49.2 0.0 1.7e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR69678.1 - 7.2e-12 46.4 0.0 9.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EMR69678.1 - 0.00042 19.1 0.0 0.00059 18.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 EMR69678.1 - 0.0034 17.5 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 EMR69678.1 - 0.0063 16.2 0.0 0.0093 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 EMR69678.1 - 0.091 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase ITAM PF02189.15 EMR69679.1 - 0.021 15.2 11.1 15 6.3 0.0 5.2 6 0 0 6 6 6 0 Immunoreceptor tyrosine-based activation motif NmrA PF05368.13 EMR69680.1 - 1.8e-07 31.0 0.0 4.1e-07 29.8 0.0 1.6 2 1 0 2 2 2 1 NmrA-like family CTP_synth_N PF06418.14 EMR69681.1 - 1.8e-86 289.7 10.0 6.1e-82 274.9 6.7 2.9 1 1 1 2 2 2 2 CTP synthase N-terminus GATase PF00117.28 EMR69681.1 - 1.1e-51 175.3 0.0 2e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMR69681.1 - 0.018 14.8 0.2 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Peptidase C26 SSF PF00474.17 EMR69682.1 - 6.7e-16 58.1 25.1 6.7e-16 58.1 25.1 2.3 1 1 1 2 2 2 1 Sodium:solute symporter family Rhomboid PF01694.22 EMR69683.1 - 1.8e-25 89.7 6.5 1.8e-25 89.7 6.5 1.5 2 0 0 2 2 2 1 Rhomboid family PhoD PF09423.10 EMR69684.1 - 4e-05 22.8 1.1 0.0026 16.8 0.1 2.6 3 0 0 3 3 3 2 PhoD-like phosphatase DUF3328 PF11807.8 EMR69685.1 - 4.9e-53 180.1 0.0 6.1e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Aldedh PF00171.22 EMR69686.1 - 3.1e-108 362.3 0.0 3.8e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lactamase_B PF00753.27 EMR69687.1 - 3.2e-08 33.8 0.6 7.5e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMR69687.1 - 0.0015 18.1 0.3 0.004 16.7 0.2 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Trp_syntA PF00290.20 EMR69689.1 - 6.6e-95 316.9 0.0 1.2e-94 316.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EMR69689.1 - 3e-51 174.6 2.7 5.2e-51 173.8 2.7 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1674 PF07896.12 EMR69690.1 - 7.8e-18 64.7 1.4 7.8e-18 64.7 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) DUF4646 PF15496.6 EMR69691.1 - 0.12 13.0 0.0 0.32 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) RhgB_N PF09284.10 EMR69693.1 - 1.9e-95 319.2 5.1 2.6e-95 318.7 5.1 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EMR69693.1 - 2.5e-34 118.6 0.0 7.7e-34 117.0 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EMR69693.1 - 1e-20 73.3 4.8 1e-20 73.3 4.8 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II DUF4278 PF14105.6 EMR69693.1 - 0.84 10.1 3.4 0.43 11.0 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4278) bZIP_1 PF00170.21 EMR69694.1 - 2.3e-09 37.2 3.6 3.5e-09 36.6 3.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMR69694.1 - 5.7e-09 35.9 3.9 1.1e-08 35.1 3.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMR69694.1 - 0.0031 18.0 2.8 0.0041 17.6 2.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 EMR69694.1 - 0.015 14.6 1.0 0.017 14.6 1.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1465 PF07323.12 EMR69694.1 - 0.02 14.8 1.0 0.022 14.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) p450 PF00067.22 EMR69695.1 - 1.2e-27 96.8 0.0 1.5e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATP-synt_C PF00137.21 EMR69696.1 - 1.8e-13 50.6 12.3 1.8e-13 50.6 12.3 2.3 3 0 0 3 3 3 1 ATP synthase subunit C Amidohydro_1 PF01979.20 EMR69698.1 - 5.4e-26 91.7 0.0 9e-25 87.7 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR69698.1 - 1.6e-12 47.7 0.0 1.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 EMR69698.1 - 0.032 14.5 0.1 0.097 13.0 0.1 1.8 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain Fungal_trans PF04082.18 EMR69699.1 - 9.6e-13 47.8 0.0 1.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_2 PF07719.17 EMR69701.1 - 0.53 10.5 2.6 1.6 9.0 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat LysM PF01476.20 EMR69702.1 - 9.6e-14 51.2 0.6 0.00023 21.1 0.0 4.4 5 0 0 5 5 5 3 LysM domain Pet127 PF08634.10 EMR69703.1 - 8e-118 392.8 3.3 8e-118 392.8 3.3 1.8 2 0 0 2 2 2 1 Mitochondrial protein Pet127 TMEM214 PF10151.9 EMR69703.1 - 8.8 4.7 12.3 19 3.5 12.3 1.6 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator GCP_N_terminal PF17681.1 EMR69704.1 - 1.1e-27 97.4 0.0 4.2e-27 95.6 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP5-Mod21 PF14609.6 EMR69704.1 - 0.0029 16.0 1.2 0.004 15.6 1.2 1.2 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 PSDC PF12588.8 EMR69705.1 - 1.3e-58 197.0 0.0 1.9e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EMR69705.1 - 1.2e-35 122.9 0.0 1.8e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EMR69705.1 - 0.00098 18.9 0.6 0.93 9.4 0.2 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like F-box-like PF12937.7 EMR69706.1 - 1.2e-05 25.0 0.0 3.4e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EMR69706.1 - 0.0074 16.1 3.2 0.26 11.2 1.5 3.2 2 1 0 2 2 2 1 F-box domain FMN_dh PF01070.18 EMR69707.1 - 9.5e-84 281.4 2.2 1.1e-48 166.0 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 EMR69707.1 - 0.00047 19.3 0.1 0.0015 17.6 0.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMR69707.1 - 0.011 15.1 0.2 0.018 14.4 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase G3P_antiterm PF04309.12 EMR69707.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Glu_synthase PF01645.17 EMR69707.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase ThiG PF05690.14 EMR69707.1 - 0.025 13.9 0.4 3.8 6.7 0.0 2.5 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 EMR69707.1 - 0.053 12.7 0.0 13 4.9 0.0 2.8 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase Peptidase_M19 PF01244.21 EMR69707.1 - 0.075 12.2 0.0 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) APH PF01636.23 EMR69708.1 - 6.4e-11 42.6 0.1 1.1e-10 41.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Adap_comp_sub PF00928.21 EMR69709.1 - 1.4e-76 257.4 0.0 1.9e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMR69709.1 - 6.3e-05 22.9 0.1 0.00012 22.1 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 EMR69709.1 - 0.034 13.6 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal muHD PF10291.9 EMR69709.1 - 0.089 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain PAP2_3 PF14378.6 EMR69711.1 - 6.9e-18 65.0 2.5 4.1e-08 33.1 1.7 2.4 2 0 0 2 2 2 2 PAP2 superfamily Glyco_hydro_61 PF03443.14 EMR69712.1 - 5e-61 206.2 0.7 6e-61 206.0 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ChiC PF06483.11 EMR69712.1 - 0.16 11.9 1.4 0.6 10.0 0.1 2.3 3 0 0 3 3 3 0 Chitinase C Guanylate_kin PF00625.21 EMR69713.1 - 3e-58 196.5 0.0 3.4e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 EMR69713.1 - 1.9e-05 24.9 0.0 7.4e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMR69713.1 - 4e-05 24.2 0.0 0.0001 22.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMR69713.1 - 0.0022 18.3 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR69713.1 - 0.0023 18.3 0.1 0.0037 17.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMR69713.1 - 0.01 15.8 0.1 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EMR69713.1 - 0.028 14.9 0.0 0.048 14.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 EMR69713.1 - 0.036 14.1 0.0 0.083 13.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EMR69713.1 - 0.039 13.7 0.1 2.5 7.8 0.1 2.2 1 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 EMR69713.1 - 0.067 13.1 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 EMR69713.1 - 0.16 12.0 0.3 1.3 9.0 0.0 2.2 2 1 0 3 3 3 0 AAA domain 4HBT_2 PF13279.6 EMR69714.1 - 2.5e-24 86.1 0.1 3.4e-24 85.7 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EMR69714.1 - 0.063 12.6 0.2 0.21 10.8 0.1 1.9 2 1 1 3 3 3 0 Acyl-ACP thioesterase Lzipper-MIP1 PF14389.6 EMR69714.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Ank_2 PF12796.7 EMR69715.1 - 2.4e-07 31.2 0.0 3.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR69715.1 - 2e-05 24.7 0.0 0.00017 21.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR69715.1 - 0.00078 20.0 0.0 0.0029 18.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR69715.1 - 0.0032 17.8 0.1 2.3 9.0 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Glyco_hydro_18 PF00704.28 EMR69717.1 - 7.8e-69 232.8 3.7 8.3e-69 232.7 2.8 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EMR69717.1 - 4e-13 49.6 12.5 4e-13 49.6 12.5 3.0 4 0 0 4 4 4 1 Chitin recognition protein Glycogen_syn PF05693.13 EMR69718.1 - 0 1096.2 0.4 9.7e-263 873.5 0.0 2.0 1 1 1 2 2 2 2 Glycogen synthase Glycos_transf_1 PF00534.20 EMR69718.1 - 0.00015 21.4 0.0 0.058 12.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMR69718.1 - 0.00047 20.6 0.0 0.68 10.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMR69718.1 - 0.11 12.4 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Phage_hub_GP28 PF11110.8 EMR69718.1 - 0.14 12.0 0.0 0.96 9.3 0.0 2.0 2 0 0 2 2 2 0 Baseplate hub distal subunit Beta-lactamase PF00144.24 EMR69719.1 - 1.4e-46 159.3 0.0 2.5e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EMR69719.1 - 5.8e-06 26.7 0.4 1.5e-05 25.4 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) DUF4855 PF16147.5 EMR69719.1 - 0.12 11.5 0.0 0.88 8.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4855) Exo_endo_phos PF03372.23 EMR69720.1 - 4.7e-16 59.0 0.3 8.3e-15 54.9 0.3 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EMR69720.1 - 3.1e-10 40.1 5.8 7.8e-07 29.3 0.6 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMR69720.1 - 1.8e-08 34.0 10.5 2.9e-06 26.9 3.1 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EMR69720.1 - 0.0091 16.4 4.7 0.24 12.1 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 EMR69720.1 - 0.095 12.8 0.1 0.095 12.8 0.1 3.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.6 EMR69720.1 - 0.1 12.1 0.6 0.2 11.2 0.6 1.4 1 0 0 1 1 1 0 Leucine-rich repeat Fasciclin PF02469.22 EMR69722.1 - 8.7e-23 80.9 0.6 1.3e-17 64.2 0.0 3.4 2 1 0 2 2 2 2 Fasciclin domain EcoRI PF02963.16 EMR69722.1 - 0.056 12.4 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease EcoRI VGCC_beta4Aa_N PF12052.8 EMR69723.1 - 0.038 14.1 0.8 0.089 12.9 0.8 1.5 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal OTCace PF00185.24 EMR69723.1 - 0.16 12.0 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LRR_6 PF13516.6 EMR69724.1 - 2.8e-16 58.1 27.3 0.071 13.2 0.0 12.6 13 0 0 13 13 13 6 Leucine Rich repeat F-box-like PF12937.7 EMR69724.1 - 5.7e-13 48.5 3.0 1.8e-12 46.9 1.4 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EMR69724.1 - 2.3e-07 31.0 23.4 1.2 9.6 0.3 7.5 2 1 8 10 10 10 7 Leucine Rich repeats (2 copies) F-box PF00646.33 EMR69724.1 - 5.1e-05 23.0 0.9 0.00021 21.1 0.9 2.2 1 0 0 1 1 1 1 F-box domain PhoLip_ATPase_C PF16212.5 EMR69725.1 - 2.4e-48 165.1 6.1 2.4e-48 165.1 6.1 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EMR69725.1 - 1e-14 55.3 0.1 5.3e-09 36.7 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 EMR69725.1 - 1.4e-08 34.3 0.2 2.9e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EMR69725.1 - 7.3e-08 32.1 0.6 0.00089 18.8 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 EMR69725.1 - 1.7e-05 24.8 0.0 0.00028 20.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMR69725.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 EMR69726.1 - 5.5e-22 77.7 2.5 0.00025 21.8 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR69726.1 - 2e-08 34.4 0.0 0.026 14.8 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EMR69726.1 - 5.5e-05 22.9 0.7 0.18 11.8 0.0 3.9 3 0 0 3 3 3 2 PQQ enzyme repeat Nup160 PF11715.8 EMR69726.1 - 0.00056 18.7 0.3 0.17 10.5 0.2 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Methyltransf_25 PF13649.6 EMR69727.1 - 2.2e-10 41.1 0.0 4.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR69727.1 - 6e-09 36.0 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR69727.1 - 3.9e-07 30.6 0.0 8.9e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR69727.1 - 0.0001 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR69727.1 - 0.0058 17.3 0.0 0.033 14.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR69727.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EMR69727.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EMR69727.1 - 0.14 13.2 0.0 0.6 11.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Cwf_Cwc_15 PF04889.12 EMR69727.1 - 0.26 11.0 1.5 0.41 10.3 1.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HD PF01966.22 EMR69728.1 - 9.2e-07 29.1 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 HD domain LysM PF01476.20 EMR69729.1 - 3.8e-31 106.9 11.3 1.6e-06 28.0 0.0 5.4 5 0 0 5 5 5 4 LysM domain HTH_Tnp_1 PF01527.20 EMR69729.1 - 0.00024 21.4 0.0 8.8 6.7 0.0 4.1 4 0 0 4 4 4 1 Transposase HTH_23 PF13384.6 EMR69729.1 - 0.00095 18.9 0.0 34 4.4 0.0 4.2 4 0 0 4 4 4 0 Homeodomain-like domain DXP_synthase_N PF13292.6 EMR69729.1 - 0.056 12.7 0.5 17 4.5 0.0 3.0 2 1 1 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase Pox_A11 PF05061.13 EMR69729.1 - 0.17 11.2 1.3 67 2.6 0.0 3.7 4 0 0 4 4 4 0 Poxvirus A11 Protein RHH_4 PF13467.6 EMR69729.1 - 0.25 11.2 1.9 1e+02 2.9 0.0 3.7 4 0 0 4 4 4 0 Ribbon-helix-helix domain AAA_22 PF13401.6 EMR69729.1 - 0.25 11.6 2.3 0.98 9.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain MAGI_u5 PF16666.5 EMR69729.1 - 2.5 8.2 5.5 1e+02 3.0 0.0 3.8 4 0 0 4 4 4 0 Unstructured region on MAGI Glyco_transf_15 PF01793.16 EMR69730.1 - 1.5e-115 385.9 11.0 1.9e-115 385.6 11.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GDI PF00996.18 EMR69731.1 - 1.7e-190 633.1 0.0 1.9e-190 633.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.27 EMR69731.1 - 0.04 14.5 0.1 3.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RE_Bsp6I PF09504.10 EMR69731.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Retrotran_gag_2 PF14223.6 EMR69732.1 - 0.00013 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EMR69732.1 - 0.0005 20.0 3.3 0.0005 20.0 3.3 2.0 2 0 0 2 2 2 1 Zinc knuckle BAH PF01426.18 EMR69733.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 EMR69733.1 - 0.0055 16.6 3.0 0.0055 16.6 3.0 2.2 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 EMR69733.1 - 0.0079 16.4 0.2 0.02 15.2 0.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain Epimerase PF01370.21 EMR69734.1 - 1.2e-22 80.5 0.0 1.6e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMR69734.1 - 1.1e-09 37.8 0.0 2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EMR69734.1 - 4.2e-06 26.4 0.0 7.2e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMR69734.1 - 2.1e-05 23.7 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EMR69734.1 - 0.0051 16.8 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EMR69734.1 - 0.0053 16.0 0.0 0.017 14.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein TrkA_N PF02254.18 EMR69734.1 - 0.0056 16.9 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.15 EMR69734.1 - 0.01 15.0 0.0 0.022 13.9 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 EMR69734.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 EMR69734.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EMR69734.1 - 0.18 12.1 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CHAP PF05257.16 EMR69735.1 - 0.079 13.6 0.5 0.22 12.1 0.5 1.8 1 1 0 1 1 1 0 CHAP domain ATG22 PF11700.8 EMR69736.1 - 8.6e-70 235.7 4.4 9.7e-70 235.5 4.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EMR69736.1 - 0.0033 16.4 13.3 0.024 13.6 13.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EMR69736.1 - 0.43 9.1 4.5 0.57 8.7 4.5 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein SH3_1 PF00018.28 EMR69737.1 - 6.8e-12 44.8 0.1 1.1e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMR69737.1 - 9e-08 31.9 0.1 1.7e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMR69737.1 - 2.6e-07 30.2 0.0 4.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3425 PF11905.8 EMR69738.1 - 3.8e-15 56.0 0.1 7.9e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF2019 PF09450.10 EMR69739.1 - 0.0068 16.3 1.1 0.26 11.3 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF2019) Metal_resist PF13801.6 EMR69739.1 - 0.035 14.3 2.5 0.066 13.4 2.5 1.5 1 1 0 1 1 1 0 Heavy-metal resistance Ribosomal_S17e PF00833.18 EMR69740.1 - 1.3e-58 196.2 0.3 1.6e-58 195.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 NmrA PF05368.13 EMR69741.1 - 7e-42 143.6 0.0 1.1e-41 142.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR69741.1 - 2.7e-08 33.9 0.1 4e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR69741.1 - 9.8e-06 25.2 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR69741.1 - 0.0006 18.9 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EMR69741.1 - 0.12 12.8 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EMR69741.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 KR domain MRP-L47 PF06984.13 EMR69743.1 - 1.8e-24 85.6 1.8 2.7e-24 85.1 1.8 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 EMR69743.1 - 0.07 13.1 4.3 0.15 12.1 4.3 1.6 1 1 0 1 1 1 0 Ribosomal L29 protein DUF1298 PF06974.13 EMR69743.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) Clc-like PF07062.12 EMR69743.1 - 0.2 11.1 1.1 0.33 10.4 1.1 1.3 1 0 0 1 1 1 0 Clc-like DUF2681 PF10883.8 EMR69743.1 - 0.22 12.0 1.3 0.47 10.9 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DLH PF01738.18 EMR69744.1 - 4.5e-07 29.6 0.0 5.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF1681 PF07933.14 EMR69745.1 - 3.2e-56 189.1 0.0 4.3e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) His_Phos_1 PF00300.22 EMR69746.1 - 4e-14 52.8 8.3 2.6e-10 40.3 0.3 4.1 4 0 0 4 4 4 4 Histidine phosphatase superfamily (branch 1) RPAP2_Rtr1 PF04181.13 EMR69749.1 - 1.2e-18 67.1 0.0 2.7e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Med8 PF10232.9 EMR69749.1 - 2.9 7.4 9.6 11 5.6 9.6 2.0 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Pes-10 PF07149.11 EMR69749.1 - 4.5 6.2 9.5 2.8 6.9 6.5 1.8 2 0 0 2 2 2 0 Pes-10 GCP_C_terminal PF04130.13 EMR69751.1 - 1.6e-24 86.9 0.0 5.1e-24 85.3 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EMR69751.1 - 1.7e-23 83.7 0.0 3.4e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal MAGE_N PF12440.8 EMR69751.1 - 1.2 9.8 7.5 3.7 8.3 7.5 1.7 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Mit_ribos_Mrp51 PF11709.8 EMR69752.1 - 8.9e-125 417.1 0.2 1.2e-124 416.6 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit zf-H2C2_2 PF13465.6 EMR69753.1 - 5.6e-07 29.7 6.6 1.5e-05 25.2 1.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 EMR69753.1 - 0.00044 20.5 4.1 0.00093 19.4 4.1 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EMR69753.1 - 0.00089 19.9 15.1 0.05 14.4 5.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Fungal_trans PF04082.18 EMR69753.1 - 0.0039 16.2 0.3 0.0073 15.4 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.8 EMR69753.1 - 0.12 12.7 3.1 7.1 7.1 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EMR69753.1 - 0.25 11.9 14.6 0.3 11.6 7.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3848 PF12959.7 EMR69754.1 - 0.2 11.7 2.6 14 5.8 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3848) Senescence PF06911.12 EMR69755.1 - 4.7e-55 186.7 7.3 6.6e-55 186.3 7.3 1.2 1 0 0 1 1 1 1 Senescence-associated protein F_actin_cap_B PF01115.17 EMR69756.1 - 9.5e-96 320.0 0.0 1.1e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pyr_redox_2 PF07992.14 EMR69757.1 - 7.2e-12 45.1 0.0 4.2e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR69757.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding MAM33 PF02330.16 EMR69758.1 - 3.3e-74 249.4 3.0 5.7e-74 248.6 3.0 1.4 1 1 0 1 1 1 1 Mitochondrial glycoprotein RhoGEF67_u2 PF16614.5 EMR69758.1 - 0.011 15.8 0.1 0.032 14.3 0.0 1.8 1 1 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 DUF963 PF06131.11 EMR69758.1 - 1.4 8.4 7.5 0.24 10.8 1.6 2.5 1 1 1 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) FRQ PF09421.10 EMR69759.1 - 6.5e-177 590.5 35.0 1.1e-176 589.8 35.0 1.3 1 0 0 1 1 1 1 Frequency clock protein Transferase PF02458.15 EMR69760.1 - 1.2e-10 40.7 0.0 1.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Transferase family Condensation PF00668.20 EMR69760.1 - 0.063 11.9 1.4 0.094 11.4 1.4 1.2 1 0 0 1 1 1 0 Condensation domain Mucin PF01456.17 EMR69760.1 - 0.088 12.8 22.8 0.16 12.0 22.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 EMR69760.1 - 6.3 4.6 4.6 8.3 4.3 4.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.8 EMR69760.1 - 9.6 5.3 13.7 15 4.6 13.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_125 PF06824.11 EMR69761.1 - 1.9e-17 63.2 0.0 3.8e-17 62.3 0.0 1.5 2 0 0 2 2 2 1 Metal-independent alpha-mannosidase (GH125) Apolipoprotein PF01442.18 EMR69762.1 - 0.0097 15.8 2.2 0.011 15.6 2.2 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YaeQ PF07152.12 EMR69762.1 - 0.07 12.7 0.2 0.086 12.4 0.2 1.3 1 1 0 1 1 1 0 YaeQ protein DUF1744 PF08490.12 EMR69763.1 - 4.7e-157 522.7 0.0 7e-157 522.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EMR69763.1 - 2.7e-68 230.6 0.0 4.2e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EMR69763.1 - 2.4e-16 59.5 0.3 6.8e-14 51.4 0.2 2.8 3 0 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EMR69763.1 - 8.3e-07 28.9 0.2 3.3e-06 27.0 0.2 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EMR69763.1 - 0.00019 21.5 0.0 0.00065 19.7 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol3_alpha PF07733.12 EMR69763.1 - 0.038 13.6 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain IBR PF01485.21 EMR69764.1 - 1.3e-22 79.8 46.7 2.9e-12 46.6 5.8 4.5 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EMR69764.1 - 4.9e-06 26.3 42.7 0.00015 21.6 6.0 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMR69764.1 - 7.5e-05 23.0 44.3 0.00024 21.4 7.3 4.1 2 1 1 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 EMR69764.1 - 0.0016 18.4 33.6 0.0098 15.9 4.6 3.9 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMR69764.1 - 0.003 17.4 44.2 0.0041 16.9 6.6 5.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMR69764.1 - 0.046 14.0 33.8 0.59 10.5 1.8 3.7 3 0 0 3 3 3 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EMR69764.1 - 0.44 10.7 31.2 0.055 13.6 1.4 4.6 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EMR69764.1 - 7.4 6.4 40.3 0.38 10.6 10.5 4.0 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain Epimerase PF01370.21 EMR69766.1 - 7.4e-14 51.8 0.0 1.4e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR69766.1 - 7e-10 38.8 0.0 0.00051 19.5 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMR69766.1 - 3.7e-06 26.9 0.6 7.5e-06 26.0 0.6 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR69766.1 - 1.8e-05 24.5 0.0 3.6e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EMR69766.1 - 0.041 13.0 0.1 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.25 EMR69766.1 - 0.044 13.2 0.1 0.093 12.2 0.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N PF00107.26 EMR69766.1 - 0.12 12.4 1.4 0.29 11.1 0.2 2.3 2 1 0 2 2 2 0 Zinc-binding dehydrogenase 3Beta_HSD PF01073.19 EMR69766.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_16 PF00722.21 EMR69767.1 - 1.1e-05 25.0 0.0 0.00015 21.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF1467 PF07330.12 EMR69767.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) PAP2 PF01569.21 EMR69768.1 - 7.3e-26 90.6 2.6 2.3e-25 89.0 2.6 1.9 1 1 0 1 1 1 1 PAP2 superfamily TPPK_C PF12555.8 EMR69768.1 - 0.032 14.3 5.0 0.85 9.7 1.3 2.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal PAP2_C PF14360.6 EMR69768.1 - 0.71 10.4 4.7 2.8 8.6 4.7 2.1 1 1 0 1 1 1 0 PAP2 superfamily C-terminal DUF2085 PF09858.9 EMR69768.1 - 1.6 9.2 4.7 0.69 10.4 1.6 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Aldose_epim PF01263.20 EMR69769.1 - 1.7e-55 188.5 0.0 2.3e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase XPG_N PF00752.17 EMR69770.1 - 3.8e-24 85.1 0.0 7.4e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EMR69770.1 - 7e-23 80.8 0.0 1.3e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EMR69770.1 - 1.8e-05 24.4 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing HHH_5 PF14520.6 EMR69770.1 - 0.016 15.8 0.4 11 6.7 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF3801 PF12687.7 EMR69770.1 - 0.072 13.2 0.1 0.29 11.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3801) TPR_16 PF13432.6 EMR69770.1 - 0.091 13.4 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Hydrolase PF00702.26 EMR69770.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Redoxin PF08534.10 EMR69771.1 - 1.2e-23 83.4 0.0 1.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMR69771.1 - 2.7e-07 30.5 0.0 3.4e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family RCC1 PF00415.18 EMR69772.1 - 5.9e-28 97.2 4.1 1.6e-07 31.8 0.0 7.1 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMR69772.1 - 3.1e-15 55.5 15.3 8.8e-12 44.5 0.0 6.4 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Phospholip_A2_3 PF09056.11 EMR69773.1 - 1.8e-39 134.8 0.0 2.1e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Glyco_hydro_11 PF00457.17 EMR69774.1 - 4.8e-80 267.4 17.8 5.5e-80 267.2 17.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 adh_short PF00106.25 EMR69775.1 - 1.1e-25 90.2 0.1 6.7e-21 74.6 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69775.1 - 1.6e-15 57.3 0.4 1.2e-14 54.4 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR69775.1 - 3.3e-11 43.4 0.1 5.5e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR69775.1 - 9.7e-05 21.9 0.0 0.00039 19.9 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase CoA_binding_2 PF13380.6 EMR69775.1 - 0.0098 16.4 0.2 0.065 13.7 0.2 2.2 2 1 1 3 3 3 1 CoA binding domain Sacchrp_dh_NADP PF03435.18 EMR69775.1 - 0.011 16.0 0.1 0.025 14.8 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EMR69775.1 - 0.035 14.0 0.3 0.053 13.4 0.3 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 EMR69775.1 - 0.046 13.2 0.1 0.083 12.3 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Tma16 PF11176.8 EMR69777.1 - 4.4e-48 162.9 6.4 5.2e-48 162.6 6.4 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF3008 PF11450.8 EMR69777.1 - 0.051 13.8 0.2 6.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Lipase_3 PF01764.25 EMR69778.1 - 1e-24 87.0 0.0 1.5e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Sec34 PF04136.15 EMR69779.1 - 4.3e-50 169.5 0.2 9.5e-50 168.4 0.2 1.6 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 EMR69779.1 - 0.047 13.5 0.2 2.1 8.1 0.0 2.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Pkinase PF00069.25 EMR69780.1 - 1.6e-07 30.9 0.0 1.4e-05 24.6 0.0 3.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR69780.1 - 1.3e-05 24.7 0.0 0.76 9.0 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase DNA_ligase_A_M PF01068.21 EMR69781.1 - 5.8e-50 169.8 0.1 1.8e-47 161.7 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EMR69781.1 - 8e-35 120.7 0.0 1.5e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EMR69781.1 - 2.5e-18 66.5 0.1 8.5e-11 42.3 0.1 3.0 3 0 0 3 3 3 2 ATP dependent DNA ligase C terminal region NuDC PF16273.5 EMR69781.1 - 0.0032 18.0 0.1 0.0032 18.0 0.1 3.3 3 0 0 3 3 3 1 Nuclear distribution C domain mRNA_cap_enzyme PF01331.19 EMR69781.1 - 0.18 11.6 0.0 7.9 6.2 0.0 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Apt1 PF10351.9 EMR69781.1 - 10 4.9 7.9 7.2 5.3 1.2 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Arylsulfotran_2 PF14269.6 EMR69782.1 - 8.8e-69 232.1 0.3 1.5e-68 231.4 0.3 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMR69782.1 - 4.9e-15 55.3 0.3 8.3e-14 51.3 0.1 2.8 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) tRNA_anti-codon PF01336.25 EMR69782.1 - 0.1 12.6 0.0 4.9 7.2 0.0 2.7 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain MFS_1 PF07690.16 EMR69783.1 - 7.5e-39 133.6 43.5 2.1e-38 132.2 41.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR69783.1 - 1.4e-09 37.4 26.6 1.4e-09 37.4 13.5 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter HSP70 PF00012.20 EMR69784.1 - 1.8e-76 257.6 0.0 2.9e-76 257.0 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMR69784.1 - 0.00019 20.3 0.2 0.012 14.4 0.1 2.8 3 0 0 3 3 3 1 MreB/Mbl protein Lipase3_N PF03893.16 EMR69786.1 - 0.084 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region Fungal_trans_2 PF11951.8 EMR69787.1 - 0.00021 20.2 0.0 0.00042 19.3 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain BSP_II PF05432.11 EMR69787.1 - 0.063 13.0 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Transketolase_C PF02780.20 EMR69787.1 - 0.09 12.7 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Transketolase, C-terminal domain Asp PF00026.23 EMR69788.1 - 7.8e-34 117.5 0.0 1e-33 117.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR69788.1 - 3.3e-05 24.2 0.6 0.0017 18.6 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal CYYR1 PF10873.8 EMR69788.1 - 0.022 15.2 0.2 0.044 14.2 0.2 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 RTA1 PF04479.13 EMR69789.1 - 3.3e-70 235.9 7.4 4e-70 235.6 7.4 1.0 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_43 PF04616.14 EMR69790.1 - 3.3e-43 148.1 0.1 2.2e-42 145.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 TackOD1 PF18551.1 EMR69791.1 - 0.032 13.9 0.9 0.053 13.2 0.9 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 LSM PF01423.22 EMR69792.1 - 2.8e-06 26.9 0.0 2.4e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 LSM domain GlutR_dimer PF00745.20 EMR69792.1 - 0.033 14.6 0.2 4.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain PsbL PF02419.17 EMR69792.1 - 0.19 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 PsbL protein Response_reg PF00072.24 EMR69793.1 - 9.9e-21 74.0 0.1 2.6e-20 72.7 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EMR69793.1 - 1.4e-14 54.5 0.0 3.4e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 EMR69793.1 - 9e-11 41.8 0.1 2.6e-09 37.1 0.0 3.2 4 0 0 4 4 4 1 PAS fold HisKA PF00512.25 EMR69793.1 - 3.9e-07 30.0 0.3 3.9e-07 30.0 0.3 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EMR69793.1 - 2e-06 28.0 0.1 7.1e-05 23.0 0.0 3.1 3 0 0 3 3 3 1 PAS domain GAF_2 PF13185.6 EMR69793.1 - 7.1e-05 23.1 0.0 0.027 14.8 0.0 2.7 3 0 0 3 3 3 1 GAF domain PAS_4 PF08448.10 EMR69793.1 - 8.3e-05 22.8 0.0 0.022 15.0 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 EMR69793.1 - 0.00012 22.0 0.0 0.00037 20.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EMR69793.1 - 0.00098 19.4 0.3 0.0023 18.2 0.3 1.6 1 0 0 1 1 1 1 PAS fold TA_inhibitor PF17574.2 EMR69793.1 - 0.0089 16.0 0.1 0.026 14.6 0.1 1.8 1 0 0 1 1 1 1 Inhibitor of toxin/antitoxin system (Gp4.5) GAF_3 PF13492.6 EMR69793.1 - 0.01 16.2 0.0 0.036 14.4 0.0 1.9 2 0 0 2 2 2 0 GAF domain DUF5527 PF17665.1 EMR69794.1 - 0.9 9.1 3.5 0.35 10.4 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5527) XPG_N PF00752.17 EMR69795.1 - 1.2e-33 115.6 0.0 2.5e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EMR69795.1 - 1.6e-25 89.3 0.0 5.2e-25 87.6 0.0 2.0 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 EMR69795.1 - 0.00051 19.8 0.1 0.00051 19.8 0.1 3.4 3 0 0 3 3 3 1 Ubiquitin interaction motif PUB_1 PF18486.1 EMR69795.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain IR1-M PF12185.8 EMR69795.1 - 0.43 10.5 4.7 2.1 8.4 0.5 3.9 2 1 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Glutaredoxin PF00462.24 EMR69796.1 - 3.4e-21 75.2 0.0 5.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.20 EMR69796.1 - 0.012 15.4 0.1 0.1 12.4 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EMR69796.1 - 0.017 15.6 0.1 0.024 15.1 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 EMR69796.1 - 0.023 15.1 0.0 0.031 14.7 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 EMR69796.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain p450 PF00067.22 EMR69797.1 - 2.3e-55 188.2 0.0 3e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_11 PF13414.6 EMR69798.1 - 1.8e-10 40.4 0.0 0.00066 19.3 0.0 3.7 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EMR69798.1 - 2.2e-07 31.1 5.0 0.00026 21.5 0.7 4.9 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMR69798.1 - 3.5e-07 29.8 1.1 3.9e-05 23.3 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR69798.1 - 2.4e-06 27.2 3.8 7.6e-05 22.5 0.6 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR69798.1 - 3.8e-06 27.3 6.8 3.9e-05 24.1 0.7 4.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMR69798.1 - 8.9e-06 25.7 0.2 0.099 13.1 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMR69798.1 - 2.2e-05 24.3 0.3 0.0013 18.8 0.2 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR69798.1 - 0.0002 21.9 5.3 0.01 16.5 1.1 4.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMR69798.1 - 0.0008 19.5 0.3 0.0033 17.5 0.2 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.6 EMR69798.1 - 0.014 15.7 1.3 1.4 9.3 0.5 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat FAT PF02259.23 EMR69798.1 - 0.018 14.3 0.0 0.16 11.2 0.0 1.9 1 1 1 2 2 2 0 FAT domain TPR_6 PF13174.6 EMR69798.1 - 0.034 14.8 4.0 1.3 9.8 0.2 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Vps5 PF09325.10 EMR69798.1 - 0.034 13.7 0.7 4.7 6.7 0.1 2.5 3 0 0 3 3 3 0 Vps5 C terminal like TPR_7 PF13176.6 EMR69798.1 - 0.081 13.0 0.1 0.9 9.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TAF1_subA PF14929.6 EMR69798.1 - 0.14 11.5 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_12 PF13424.6 EMR69798.1 - 0.15 12.4 9.0 0.27 11.5 0.4 4.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_25 PF13649.6 EMR69799.1 - 5.9e-18 65.4 0.0 1.2e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR69799.1 - 1.2e-17 64.4 0.1 1.3e-16 61.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR69799.1 - 3.3e-15 56.5 0.0 6.6e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR69799.1 - 2.7e-12 46.8 0.0 3.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR69799.1 - 1.5e-11 44.4 0.0 1.4e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR69799.1 - 2.2e-10 40.2 0.0 3.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMR69799.1 - 5.8e-05 22.7 0.0 9.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 EMR69799.1 - 0.0003 21.8 0.1 0.00086 20.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EMR69799.1 - 0.0014 17.9 0.0 0.31 10.2 0.0 2.3 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 EMR69799.1 - 0.0015 18.4 0.0 0.004 17.0 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.9 EMR69799.1 - 0.0034 17.1 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase CMAS PF02353.20 EMR69799.1 - 0.0067 15.7 0.1 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase DUF3419 PF11899.8 EMR69799.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) DUF3298 PF11738.8 EMR69799.1 - 0.025 15.6 1.1 0.19 12.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) Methyltransf_32 PF13679.6 EMR69799.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Frag1 PF10277.9 EMR69800.1 - 4.3e-39 134.3 19.6 5e-39 134.1 19.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Tmemb_55A PF09788.9 EMR69800.1 - 0.44 9.6 1.5 0.68 9.0 1.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A DUF2070 PF09843.9 EMR69800.1 - 4.6 5.4 15.7 0.41 8.9 10.6 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Chalcone_2 PF16035.5 EMR69801.1 - 8.4e-76 254.3 0.0 1.1e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EMR69801.1 - 0.01 16.0 0.0 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Chalcone isomerase-like SPT_ssu-like PF11779.8 EMR69802.1 - 0.17 11.5 0.2 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like Y_phosphatase3 PF13350.6 EMR69803.1 - 5.5e-43 147.6 0.1 9.4e-43 146.8 0.1 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EMR69803.1 - 8.2e-05 22.2 0.0 0.00041 20.0 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 EMR69803.1 - 0.0054 15.7 0.1 0.011 14.7 0.0 1.5 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 EMR69803.1 - 0.0075 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EMR69803.1 - 0.021 14.6 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Glyco_hyd_65N_2 PF14498.6 EMR69804.1 - 9e-12 45.3 0.0 1.6e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain RHS_repeat PF05593.14 EMR69804.1 - 0.11 13.1 0.8 2.2 8.9 0.1 3.1 3 0 0 3 3 3 0 RHS Repeat Ribosomal_L13 PF00572.18 EMR69805.1 - 1.4e-10 41.5 0.0 1.2e-08 35.3 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 p450 PF00067.22 EMR69806.1 - 6.1e-43 147.2 0.0 9.5e-22 77.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 EF-hand_7 PF13499.6 EMR69807.1 - 0.011 16.2 0.0 0.22 12.0 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair SWIRM-assoc_3 PF16498.5 EMR69807.1 - 0.11 12.8 1.3 1.2 9.4 0.0 3.0 3 1 1 4 4 4 0 SWIRM-associated domain at the C-terminal IGR PF09597.10 EMR69808.1 - 5.4e-25 87.3 0.3 9.3e-25 86.5 0.3 1.4 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.30 EMR69808.1 - 0.0014 19.0 0.0 0.0025 18.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EELM2 PF15863.5 EMR69808.1 - 0.044 13.9 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain Polyketide_cyc PF03364.20 EMR69809.1 - 1.4e-23 83.5 0.1 6.1e-23 81.4 0.1 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EMR69809.1 - 0.00013 22.2 1.6 0.51 10.6 0.1 2.7 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport AIM5 PF17050.5 EMR69809.1 - 0.58 11.0 3.1 2.3 9.1 3.1 2.0 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 Spt20 PF12090.8 EMR69810.1 - 0.0078 15.8 9.0 0.0078 15.8 9.0 2.1 2 0 0 2 2 2 1 Spt20 family bZIP_2 PF07716.15 EMR69810.1 - 0.024 14.7 11.7 0.024 14.7 11.7 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.25 EMR69811.1 - 2.1e-65 220.7 0.0 2.5e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR69811.1 - 4.6e-35 121.1 0.0 6.7e-35 120.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR69811.1 - 0.0031 16.9 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EMR69811.1 - 0.03 13.3 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 EMR69811.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SfsA PF03749.13 EMR69811.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain Pkinase_fungal PF17667.1 EMR69811.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Eisosome1 PF12757.7 EMR69812.1 - 1e-40 138.9 12.2 1e-40 138.9 12.2 3.1 2 1 1 3 3 3 1 Eisosome protein 1 CAF-1_p150 PF11600.8 EMR69812.1 - 0.65 9.7 32.8 0.018 14.8 25.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Promethin PF16015.5 EMR69813.1 - 1.5e-27 95.6 16.1 1.9e-27 95.2 16.1 1.1 1 0 0 1 1 1 1 Promethin Anoctamin PF04547.12 EMR69813.1 - 0.011 14.6 0.5 0.013 14.4 0.5 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel FA_desaturase PF00487.24 EMR69813.1 - 0.054 13.3 3.8 0.07 13.0 3.8 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Helicase_C PF00271.31 EMR69814.1 - 7.6e-06 26.2 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BAG PF02179.16 EMR69815.1 - 3.9e-20 72.0 0.1 8.3e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EMR69815.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YqfQ PF14181.6 EMR69815.1 - 0.32 11.2 5.0 1.7 8.8 3.1 2.2 2 0 0 2 2 2 0 YqfQ-like protein DUF89 PF01937.19 EMR69817.1 - 2.3e-129 431.4 0.0 2.8e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Peptidase_S8 PF00082.22 EMR69818.1 - 8.6e-35 120.4 1.6 1.8e-34 119.4 1.6 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR69818.1 - 8.8e-09 35.9 0.2 1.9e-08 34.9 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glyco_hydro_61 PF03443.14 EMR69820.1 - 0.00062 19.8 0.0 0.0018 18.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 E1_DerP2_DerF2 PF02221.15 EMR69821.1 - 6.8e-27 94.5 0.3 8.2e-27 94.3 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EMR69821.1 - 0.0053 17.1 0.1 0.011 16.1 0.1 1.5 1 1 0 1 1 1 1 ML-like domain CopC PF04234.12 EMR69821.1 - 0.018 16.1 0.0 0.027 15.5 0.0 1.4 1 0 0 1 1 1 0 CopC domain Big_9 PF17963.1 EMR69821.1 - 0.028 15.2 0.1 0.071 13.9 0.1 1.7 2 0 0 2 2 2 0 Bacterial Ig domain RSN1_7TM PF02714.15 EMR69822.1 - 2.5e-87 292.7 27.0 2.5e-87 292.7 27.0 2.8 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMR69822.1 - 4.5e-47 159.7 2.4 4.5e-47 159.7 2.4 3.2 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMR69822.1 - 6.9e-35 120.9 0.0 1e-34 120.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EMR69822.1 - 3.4e-33 113.7 0.2 8e-33 112.5 0.1 1.7 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 EMR69822.1 - 0.18 12.1 1.2 1.4 9.2 0.3 2.6 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A DUF2418 PF10332.9 EMR69824.1 - 1.3e-37 128.2 0.2 5.7e-37 126.1 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 EMR69825.1 - 1.1e-34 118.7 0.2 1.2e-34 118.5 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF61 PF01886.16 EMR69825.1 - 0.014 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF61 Jag_N PF14804.6 EMR69825.1 - 0.097 13.0 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Jag N-terminus CK2S PF15011.6 EMR69826.1 - 0.0039 17.1 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 Casein Kinase 2 substrate SNCAIP_SNCA_bd PF16700.5 EMR69826.1 - 0.084 12.6 1.1 0.2 11.4 0.3 2.1 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain NPV_P10 PF05531.12 EMR69826.1 - 0.38 11.2 2.8 2.5 8.6 0.2 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein p450 PF00067.22 EMR69827.1 - 6.5e-63 213.1 0.0 8.4e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 EMR69828.1 - 1.1e-05 24.5 0.0 0.00011 21.1 0.0 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.13 EMR69829.1 - 5.3e-63 212.7 0.0 6.5e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR69829.1 - 6.4e-17 62.0 0.0 8.9e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR69829.1 - 0.032 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CBM-like PF14683.6 EMR69832.1 - 8.1e-23 81.1 0.0 1.4e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EMR69832.1 - 1.2e-21 76.3 0.0 3.6e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II Cupin_2 PF07883.11 EMR69833.1 - 2.8e-08 33.4 0.5 1.2e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EMR69833.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Ppnp PF06865.11 EMR69833.1 - 0.18 12.2 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine/purine nucleoside phosphorylase Kdo PF06293.14 EMR69834.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rad51 PF08423.11 EMR69834.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad51 DSPc PF00782.20 EMR69835.1 - 2.9e-10 40.1 0.0 6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMR69835.1 - 0.00012 21.7 0.1 0.00043 19.9 0.1 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EMR69835.1 - 0.0052 16.8 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EMR69835.1 - 0.07 13.2 0.0 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 EMR69835.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Ndc1_Nup PF09531.10 EMR69835.1 - 5.4 5.6 6.8 7.5 5.1 6.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0121 PF03661.13 EMR69836.1 - 6.3e-32 110.9 2.3 8.4e-32 110.5 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) La PF05383.17 EMR69837.1 - 4e-19 68.4 0.0 6.2e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EMR69837.1 - 9.1e-07 28.6 0.6 2.8e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 EMR69838.1 - 5e-42 144.1 15.2 5e-42 144.1 15.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR69838.1 - 3.4e-09 36.1 7.4 1e-08 34.5 1.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.18 EMR69839.1 - 8.4e-42 143.0 0.1 1e-41 142.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain LSM PF01423.22 EMR69840.1 - 3.2e-15 55.6 0.0 6e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 LSM domain SAP18 PF06487.12 EMR69840.1 - 0.021 15.0 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Pox_I1 PF03289.13 EMR69840.1 - 0.057 12.5 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus protein I1 DUF3246 PF11596.8 EMR69841.1 - 0.046 13.1 3.1 0.031 13.7 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PPR_3 PF13812.6 EMR69842.1 - 1.7e-16 60.1 0.0 0.00018 21.5 0.0 5.3 4 3 1 5 5 5 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 EMR69842.1 - 7.7e-10 38.8 0.4 0.096 12.9 0.0 5.9 7 2 1 8 8 8 3 PPR repeat family PPR PF01535.20 EMR69842.1 - 1.1e-09 37.8 0.0 17 5.9 0.0 7.7 8 0 0 8 8 8 2 PPR repeat PPR_long PF17177.4 EMR69842.1 - 3.3e-06 26.6 0.1 0.033 13.6 0.0 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP ALAD PF00490.21 EMR69842.1 - 0.086 12.0 0.1 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase Septin PF00735.18 EMR69843.1 - 9.3e-120 399.1 0.1 9.3e-120 399.1 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EMR69843.1 - 1.1e-08 35.1 0.8 2.2e-08 34.1 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR69843.1 - 5.7e-05 23.1 2.5 0.0035 17.3 0.8 3.3 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EMR69843.1 - 8.4e-05 22.2 2.0 0.0025 17.4 0.0 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EMR69843.1 - 0.00012 22.5 0.9 0.028 14.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EMR69843.1 - 0.0022 18.4 0.1 0.0064 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 EMR69843.1 - 0.0037 16.6 1.6 0.0088 15.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 EMR69843.1 - 0.0041 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EMR69843.1 - 0.0087 15.7 0.3 0.07 12.7 0.0 2.5 3 0 0 3 3 3 1 Ras family AAA_29 PF13555.6 EMR69843.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EMR69843.1 - 0.018 15.3 1.3 0.038 14.2 0.0 2.3 2 2 1 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EMR69843.1 - 0.064 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EMR69843.1 - 0.066 13.3 7.2 1.2 9.2 0.0 3.8 4 1 0 4 4 3 0 Dynamin family AAA_24 PF13479.6 EMR69843.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR69843.1 - 0.094 13.1 0.6 0.77 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 EMR69843.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EMR69843.1 - 0.61 9.8 3.3 13 5.5 0.0 3.0 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 EMR69843.1 - 1.7 8.2 8.2 2.6 7.5 8.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 EMR69843.1 - 5 7.1 6.1 5.5 7.0 0.0 2.5 3 0 0 3 3 2 0 Helicase HerA, central domain Atg14 PF10186.9 EMR69843.1 - 6.3 5.8 8.8 9.3 5.2 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Strep_SA_rep PF06696.11 EMR69843.1 - 7.5 6.7 6.9 2.8 8.0 3.5 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Fe-ADH PF00465.19 EMR69844.1 - 1.7e-60 204.7 0.2 2.2e-60 204.4 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMR69844.1 - 2.6e-09 37.2 2.2 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Glyco_tranf_2_5 PF13712.6 EMR69845.1 - 0.26 11.0 0.0 0.32 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family K_channel_TID PF07941.11 EMR69845.1 - 0.27 11.7 12.4 0.53 10.8 12.4 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain S4 PF01479.25 EMR69846.1 - 2.1e-16 59.4 0.9 7e-13 48.1 0.3 3.2 3 0 0 3 3 3 2 S4 domain zf-rbx1 PF12678.7 EMR69847.1 - 7.4e-25 87.0 12.9 1.1e-24 86.5 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EMR69847.1 - 5.2e-17 61.7 9.8 6.8e-17 61.3 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EMR69847.1 - 5e-06 26.7 14.4 0.00018 21.8 14.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EMR69847.1 - 0.0016 18.3 11.3 0.027 14.4 11.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMR69847.1 - 0.0016 18.2 14.2 0.11 12.3 14.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR69847.1 - 0.19 11.6 10.6 0.56 10.1 4.3 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMR69847.1 - 0.33 10.7 15.8 27 4.6 15.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EMR69847.1 - 0.45 10.6 6.9 1.7 8.8 6.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 EMR69847.1 - 1.1 9.5 9.2 5.9 7.1 9.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EMR69847.1 - 1.4 8.6 14.9 0.32 10.7 4.8 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EMR69847.1 - 7.2 6.7 12.3 62 3.7 12.3 2.5 1 1 0 1 1 1 0 zinc-RING finger domain ELFV_dehydrog PF00208.21 EMR69848.1 - 6.3e-64 216.0 0.0 9.7e-64 215.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EMR69848.1 - 1.5e-19 69.2 0.0 3.4e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EMR69848.1 - 0.02 14.8 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Tyr-DNA_phospho PF06087.12 EMR69849.1 - 7.6e-10 38.2 0.3 1e-09 37.8 0.3 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 EMR69849.1 - 0.012 15.5 1.3 0.012 15.5 1.3 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif CorA PF01544.18 EMR69850.1 - 2.4e-39 135.4 0.0 3.2e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein LRRC37AB_C PF14914.6 EMR69851.1 - 0.0049 16.8 0.1 0.0075 16.2 0.1 1.2 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain AgrB PF04647.15 EMR69851.1 - 0.009 15.3 2.3 0.009 15.3 2.3 1.6 1 1 1 2 2 2 1 Accessory gene regulator B DUF3087 PF11286.8 EMR69851.1 - 0.04 13.4 0.5 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) UPF0182 PF03699.13 EMR69851.1 - 0.074 11.2 1.6 0.077 11.1 1.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Chordopox_A33R PF05966.12 EMR69851.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF2070 PF09843.9 EMR69851.1 - 0.15 10.3 3.4 0.17 10.1 3.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DHHC PF01529.20 EMR69851.1 - 0.17 12.0 6.5 0.11 12.6 5.0 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4131 PF13567.6 EMR69851.1 - 0.27 10.9 2.1 0.41 10.3 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4199 PF13858.6 EMR69851.1 - 0.46 10.9 7.5 0.047 14.1 1.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF3272 PF11676.8 EMR69851.1 - 5.9 7.2 8.9 0.16 12.2 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) Dynamin_N PF00350.23 EMR69852.1 - 2.2e-31 109.2 0.0 4.6e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EMR69852.1 - 2.2e-30 105.8 0.8 5.7e-30 104.5 0.3 2.0 1 1 1 2 2 2 1 Dynamin central region GED PF02212.18 EMR69852.1 - 0.00023 21.2 0.5 0.0026 17.9 0.0 2.8 4 0 0 4 4 4 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EMR69852.1 - 0.00058 19.9 0.1 0.0039 17.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EMR69852.1 - 0.031 14.5 0.2 0.093 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2478 PF10649.9 EMR69852.1 - 0.063 12.9 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) HET PF06985.11 EMR69853.1 - 9.6e-24 84.4 0.4 2.4e-23 83.1 0.4 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.8 EMR69855.1 - 6.5e-08 31.8 0.6 3.1e-07 29.5 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain CDP-OH_P_transf PF01066.21 EMR69856.1 - 1.1e-06 29.3 0.0 1.1e-06 29.3 0.0 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Proteasome PF00227.26 EMR69857.1 - 6.5e-57 192.1 0.2 9.5e-57 191.6 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMR69857.1 - 1.1e-11 44.1 0.4 3.6e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CHY PF05495.12 EMR69858.1 - 2.2e-12 47.3 20.6 3.8e-12 46.5 20.6 1.4 1 0 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 EMR69858.1 - 0.65 9.9 13.1 4.9 7.1 2.5 3.5 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Evr1_Alr PF04777.13 EMR69858.1 - 6.9 7.2 11.3 82 3.8 11.3 2.5 1 1 0 1 1 1 0 Erv1 / Alr family C1_4 PF07975.12 EMR69858.1 - 8.6 6.7 16.5 5.2 7.4 0.3 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain SPC12 PF06645.13 EMR69859.1 - 1.5e-29 101.9 0.2 1.8e-29 101.6 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) UCR_Fe-S_N PF10399.9 EMR69859.1 - 0.35 10.2 2.2 0.51 9.7 1.1 1.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ribosomal_S13 PF00416.22 EMR69860.1 - 2.2e-15 57.2 0.4 8.3e-12 45.6 1.8 2.1 1 1 1 2 2 2 2 Ribosomal protein S13/S18 N-SET PF11764.8 EMR69861.1 - 1.9e-51 174.6 1.3 1.9e-51 174.6 1.3 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 EMR69861.1 - 6.8e-20 72.1 0.2 6.8e-20 72.1 0.2 3.2 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.8 EMR69861.1 - 3.6e-18 65.0 0.3 2.5e-17 62.2 0.1 2.5 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.22 EMR69861.1 - 0.0055 16.5 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.26 EMR69862.1 - 4.5e-36 124.1 0.0 6.3e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.20 EMR69862.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) GluRS_N PF18466.1 EMR69862.1 - 0.24 11.8 1.7 0.48 10.9 1.7 1.6 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain Apt1 PF10351.9 EMR69864.1 - 0.0079 15.1 1.1 0.012 14.5 1.1 1.4 1 0 0 1 1 1 1 Golgi-body localisation protein domain Zip PF02535.22 EMR69864.1 - 0.011 15.0 1.2 0.017 14.4 1.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EMR69864.1 - 0.019 13.7 5.9 0.033 12.9 5.9 1.3 1 0 0 1 1 1 0 Presenilin DUF2681 PF10883.8 EMR69864.1 - 0.066 13.6 0.2 0.17 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) ABC2_membrane_3 PF12698.7 EMR69864.1 - 0.17 11.0 1.4 0.22 10.6 1.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Tim54 PF11711.8 EMR69864.1 - 0.23 10.2 4.3 0.36 9.6 4.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 EMR69864.1 - 2.5 6.2 9.8 3.4 5.8 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 EMR69864.1 - 3.4 6.6 6.0 4.8 6.1 6.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 EMR69864.1 - 4 6.4 4.2 6.5 5.7 4.2 1.4 1 1 0 1 1 1 0 CLN3 protein BUD22 PF09073.10 EMR69864.1 - 4.7 6.4 18.0 8.9 5.5 18.0 1.4 1 0 0 1 1 1 0 BUD22 ATP-synt_S1 PF05827.12 EMR69865.1 - 3.1e-06 27.1 0.0 4.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.9 EMR69866.1 - 1.2e-40 139.1 14.8 1.2e-40 139.1 14.8 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Nop53 PF07767.11 EMR69866.1 - 2 7.7 36.5 0.23 10.8 18.0 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 EMR69866.1 - 7.2 4.8 25.8 0.25 9.6 12.5 2.0 2 0 0 2 2 2 0 CDC45-like protein DEAD PF00270.29 EMR69867.1 - 1e-48 165.4 0.0 3.2e-48 163.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR69867.1 - 3.4e-32 111.1 0.0 8.9e-32 109.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR69867.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 EMR69867.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EMR69867.1 - 0.21 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RhoGAP PF00620.27 EMR69868.1 - 8.2e-16 58.2 0.6 4.8e-15 55.7 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 EMR69868.1 - 7.2e-12 45.2 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EMR69868.1 - 1.5e-11 44.4 0.1 5.3e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Med4 PF10018.9 EMR69868.1 - 0.0059 16.3 0.1 0.0059 16.3 0.1 2.6 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 BAR PF03114.18 EMR69868.1 - 0.17 11.5 4.9 0.044 13.4 1.2 1.8 2 0 0 2 2 2 0 BAR domain ABC_membrane PF00664.23 EMR69869.1 - 5.3e-55 187.0 36.5 5.4e-34 118.1 17.8 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EMR69869.1 - 6e-46 156.4 0.1 1.6e-25 90.2 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_16 PF13191.6 EMR69869.1 - 3.1e-06 27.7 0.1 0.03 14.7 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EMR69869.1 - 8.5e-05 21.9 0.0 0.0051 16.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 EMR69869.1 - 0.00018 21.5 2.5 0.06 13.4 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 EMR69869.1 - 0.00076 19.6 0.9 0.13 12.4 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EMR69869.1 - 0.00087 19.2 1.3 0.36 10.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EMR69869.1 - 0.0015 18.3 0.5 1.2 8.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EMR69869.1 - 0.0018 17.7 0.5 9.4 5.6 0.0 3.4 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMR69869.1 - 0.0027 17.4 1.2 2.1 8.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EMR69869.1 - 0.0054 16.6 0.3 2.5 7.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMR69869.1 - 0.0055 17.2 2.2 3.9 7.9 0.1 3.2 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 EMR69869.1 - 0.0093 15.0 0.9 3.2 6.7 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EMR69869.1 - 0.011 16.0 0.6 9.2 6.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EMR69869.1 - 0.012 14.6 0.6 1.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 EMR69869.1 - 0.014 14.9 0.4 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 EMR69869.1 - 0.027 14.7 0.2 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EMR69869.1 - 0.028 14.3 0.9 0.21 11.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 EMR69869.1 - 0.054 13.1 0.2 0.75 9.4 0.1 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 EMR69869.1 - 0.08 12.6 0.0 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 EMR69869.1 - 0.1 12.2 0.1 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMR69869.1 - 0.22 11.9 0.2 36 4.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.7 EMR69869.1 - 0.23 10.3 0.9 0.47 9.3 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.19 EMR69869.1 - 0.28 10.8 2.3 0.68 9.5 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EMR69869.1 - 0.84 8.8 2.7 12 5.0 0.3 2.3 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 EMR69869.1 - 2.8 7.7 5.6 16 5.1 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EMR69869.1 - 5.1 7.1 9.6 1.3 9.0 0.7 2.9 3 0 0 3 3 2 0 Dynamin family Tropomyosin_1 PF12718.7 EMR69870.1 - 6.1e-52 175.6 31.3 7.7e-52 175.2 31.3 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EMR69870.1 - 2e-07 30.6 30.3 0.00014 21.3 12.5 2.9 1 1 2 3 3 3 3 Tropomyosin ATG16 PF08614.11 EMR69870.1 - 0.00015 22.0 32.7 0.076 13.2 14.4 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 EMR69870.1 - 0.00061 19.8 29.3 0.17 12.0 1.3 5.1 3 1 2 5 5 5 3 bZIP transcription factor FlaC_arch PF05377.11 EMR69870.1 - 0.00087 19.6 19.0 0.49 10.8 0.3 4.2 3 1 1 4 4 4 2 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 EMR69870.1 - 0.0018 17.6 25.0 0.083 12.2 8.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 EMR69870.1 - 0.0032 17.5 5.5 0.0032 17.5 5.5 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 EMR69870.1 - 0.0037 16.9 33.0 0.19 11.3 19.4 2.4 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF724 PF05266.14 EMR69870.1 - 0.0052 16.6 24.8 0.022 14.6 8.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF724) Laminin_II PF06009.12 EMR69870.1 - 0.006 16.6 5.4 0.006 16.6 5.4 2.2 1 1 1 2 2 2 1 Laminin Domain II NPV_P10 PF05531.12 EMR69870.1 - 0.0068 16.8 9.7 0.069 13.6 0.2 3.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.6 EMR69870.1 - 0.0076 16.6 30.6 0.019 15.4 14.7 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 EMR69870.1 - 0.012 14.5 31.3 0.0075 15.2 18.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 EMR69870.1 - 0.013 15.9 33.7 0.025 14.9 13.8 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Rab5-bind PF09311.11 EMR69870.1 - 0.014 14.9 9.7 0.014 14.9 9.7 2.1 1 1 0 2 2 2 0 Rabaptin-like protein CtIP_N PF10482.9 EMR69870.1 - 0.019 15.0 5.3 0.019 15.0 5.3 2.9 1 1 2 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Taxilin PF09728.9 EMR69870.1 - 0.02 14.1 28.0 1.4 8.1 15.8 2.2 1 1 0 1 1 1 0 Myosin-like coiled-coil protein BRE1 PF08647.11 EMR69870.1 - 0.022 14.8 29.0 0.99 9.5 10.5 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.9 EMR69870.1 - 0.025 13.7 20.9 0.016 14.3 9.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EMR69870.1 - 0.034 14.2 30.5 0.35 11.0 8.7 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding KELK PF15796.5 EMR69870.1 - 0.034 14.6 31.2 0.15 12.5 4.8 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ERM PF00769.19 EMR69870.1 - 0.041 13.7 34.5 0.071 12.9 17.0 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CALCOCO1 PF07888.11 EMR69870.1 - 0.045 12.6 30.3 0.36 9.6 11.1 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like KLRAQ PF10205.9 EMR69870.1 - 0.047 13.9 22.1 0.38 11.0 4.8 3.2 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Phage_GP20 PF06810.11 EMR69870.1 - 0.051 13.4 27.2 1.1 9.0 3.6 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 GAS PF13851.6 EMR69870.1 - 0.063 12.6 31.7 2.1 7.7 31.8 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MAD PF05557.13 EMR69870.1 - 0.064 11.6 25.3 0.18 10.1 11.1 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein KASH_CCD PF14662.6 EMR69870.1 - 0.064 13.1 32.2 0.58 10.0 25.1 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 EMR69870.1 - 0.08 13.5 38.3 0.19 12.2 23.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 EMR69870.1 - 0.11 12.9 27.0 0.16 12.4 25.9 1.5 1 1 0 1 1 1 0 Fez1 DUF1664 PF07889.12 EMR69870.1 - 0.12 12.4 13.4 0.1 12.7 2.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 EMR69870.1 - 0.13 12.3 29.9 0.058 13.5 6.5 4.1 2 2 2 4 4 4 0 Centrosome localisation domain of PPC89 VGPC1_C PF16799.5 EMR69870.1 - 0.14 12.2 10.9 0.26 11.3 2.4 3.4 2 1 1 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Jnk-SapK_ap_N PF09744.9 EMR69870.1 - 0.19 12.0 32.1 0.095 12.9 19.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CLZ PF16526.5 EMR69870.1 - 0.21 12.0 25.4 2.4 8.6 5.9 3.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CEP63 PF17045.5 EMR69870.1 - 0.21 11.5 24.4 0.26 11.2 24.4 1.0 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa TMF_TATA_bd PF12325.8 EMR69870.1 - 0.21 11.8 25.9 12 6.2 17.2 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HMMR_N PF15905.5 EMR69870.1 - 0.27 10.7 29.3 0.56 9.6 29.3 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ZapB PF06005.12 EMR69870.1 - 0.34 11.4 39.6 1.7 9.2 1.9 4.4 1 1 2 3 3 3 0 Cell division protein ZapB BLOC1_2 PF10046.9 EMR69870.1 - 0.34 11.2 21.4 0.37 11.1 1.7 3.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2730 PF10805.8 EMR69870.1 - 0.39 10.8 13.6 0.19 11.8 2.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF4686 PF15742.5 EMR69870.1 - 0.41 9.7 32.3 4.1 6.5 32.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) TRAF_BIRC3_bd PF16673.5 EMR69870.1 - 0.44 10.4 13.3 0.53 10.1 1.0 3.4 2 2 1 4 4 3 0 TNF receptor-associated factor BIRC3 binding domain WXG100 PF06013.12 EMR69870.1 - 0.54 10.5 13.4 3.1 8.1 0.3 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Cep57_MT_bd PF06657.13 EMR69870.1 - 0.57 10.7 20.3 0.45 11.0 2.1 3.5 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 UPF0242 PF06785.11 EMR69870.1 - 0.61 10.2 30.8 3.3 7.8 14.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 EMR69870.1 - 0.75 9.3 25.4 2.7 7.4 22.4 1.9 1 1 0 1 1 1 0 Leucine zipper CENP-H PF05837.12 EMR69870.1 - 0.79 10.2 23.8 2.1 8.8 0.7 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) JAKMIP_CC3 PF16034.5 EMR69870.1 - 0.83 9.6 23.1 0.4 10.6 1.2 3.1 1 1 2 3 3 3 0 JAKMIP CC3 domain DUF5082 PF16888.5 EMR69870.1 - 0.86 9.9 20.5 2.4 8.4 8.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Sec34 PF04136.15 EMR69870.1 - 1 9.2 15.2 0.32 10.9 4.1 2.3 2 0 0 2 2 2 0 Sec34-like family DUF4472 PF14739.6 EMR69870.1 - 1.1 10.1 26.4 75 4.1 4.9 2.9 1 1 1 2 2 1 0 Domain of unknown function (DUF4472) SOGA PF11365.8 EMR69870.1 - 1.1 10.5 25.4 4.4 8.5 10.8 3.4 1 1 2 3 3 3 0 Protein SOGA TMF_DNA_bd PF12329.8 EMR69870.1 - 1.1 9.3 35.5 2.1 8.4 14.7 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 EMR69870.1 - 1.1 9.9 23.5 1.4e+04 -3.2 23.5 3.3 1 1 0 1 1 0 0 Initiation control protein YabA EzrA PF06160.12 EMR69870.1 - 1.2 7.2 23.1 2.6 6.1 19.7 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 EMR69870.1 - 1.3 9.1 34.6 1.5 8.9 9.7 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 EMR69870.1 - 1.4 9.3 15.8 2 8.8 13.5 2.2 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF2203 PF09969.9 EMR69870.1 - 1.5 9.5 16.6 0.38 11.5 4.1 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) T3SSipB PF16535.5 EMR69870.1 - 1.6 9.2 16.1 6.3 7.3 4.8 2.8 1 1 2 3 3 3 0 Type III cell invasion protein SipB Peptidase_S64 PF08192.11 EMR69870.1 - 2 6.8 12.0 2.3 6.6 12.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4618 PF15397.6 EMR69870.1 - 2.2 7.6 24.3 2e+02 1.2 24.3 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4201 PF13870.6 EMR69870.1 - 2.2 8.0 25.7 3 7.6 10.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) FapA PF03961.13 EMR69870.1 - 2.3 6.7 24.2 0.032 12.8 10.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DivIC PF04977.15 EMR69870.1 - 2.5 7.9 29.9 0.38 10.5 1.9 4.4 2 1 2 4 4 4 0 Septum formation initiator BST2 PF16716.5 EMR69870.1 - 2.5 8.7 27.2 0.1 13.2 7.8 3.2 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 OmpH PF03938.14 EMR69870.1 - 2.6 8.4 32.4 0.3 11.4 5.1 3.0 1 1 1 2 2 1 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 EMR69870.1 - 2.7 5.4 25.0 3.7 4.9 25.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4482 PF14818.6 EMR69870.1 - 3 8.7 23.9 0.14 13.0 4.2 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4482) HAP1_N PF04849.13 EMR69870.1 - 3 6.9 30.2 13 4.9 30.2 2.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Seryl_tRNA_N PF02403.22 EMR69870.1 - 3.2 8.0 26.2 3.5 7.9 8.5 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 EMR69870.1 - 3.6 8.2 19.4 8.2 7.0 7.5 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HOOK PF05622.12 EMR69870.1 - 3.6 5.6 29.6 19 3.2 29.6 1.9 1 1 0 1 1 1 0 HOOK protein DUF4407 PF14362.6 EMR69870.1 - 4.2 6.6 21.9 0.73 9.1 7.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 EMR69870.1 - 4.4 7.2 31.7 1.8 8.5 3.7 3.7 1 1 2 3 3 3 0 Axonemal dynein light chain DUF745 PF05335.13 EMR69870.1 - 4.4 7.0 16.5 0.19 11.5 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PI3K_P85_iSH2 PF16454.5 EMR69870.1 - 5.3 6.6 26.9 49 3.5 1.0 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Dynamitin PF04912.14 EMR69870.1 - 5.6 6.2 26.6 0.32 10.3 1.1 3.0 1 1 1 2 2 2 0 Dynamitin XhlA PF10779.9 EMR69870.1 - 5.6 7.2 23.1 3.9 7.7 2.3 3.9 2 1 3 5 5 5 0 Haemolysin XhlA HemX PF04375.14 EMR69870.1 - 6.4 6.0 23.0 6.7 5.9 9.9 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase IFT46_B_C PF12317.8 EMR69870.1 - 6.4 6.4 8.9 1.8 8.3 5.1 1.6 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Paralemmin PF03285.15 EMR69870.1 - 6.6 6.2 20.8 4.2 6.9 3.4 2.1 1 1 1 2 2 2 0 Paralemmin SHE3 PF17078.5 EMR69870.1 - 6.6 6.4 24.6 0.53 10.0 2.8 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 PRKG1_interact PF15898.5 EMR69870.1 - 7.8 7.5 29.3 1.3 9.9 13.5 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TMPIT PF07851.13 EMR69870.1 - 8.1 5.6 20.9 6.7 5.8 3.8 2.0 1 1 1 2 2 2 0 TMPIT-like protein FAM76 PF16046.5 EMR69870.1 - 8.1 5.7 22.2 1.3e+02 1.7 22.2 2.0 1 1 0 1 1 1 0 FAM76 protein CASP_C PF08172.12 EMR69870.1 - 8.4 5.7 22.3 0.084 12.2 1.4 2.5 1 1 1 2 2 2 0 CASP C terminal DUF4795 PF16043.5 EMR69870.1 - 9.1 5.8 25.5 1.3e+02 2.1 25.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KxDL PF10241.9 EMR69870.1 - 9.6 6.6 17.7 2 8.7 2.0 3.6 1 1 3 4 4 4 0 Uncharacterized conserved protein AAA_13 PF13166.6 EMR69870.1 - 9.6 4.7 23.5 2 6.9 9.7 2.0 1 1 1 2 2 2 0 AAA domain Fmp27_WPPW PF10359.9 EMR69870.1 - 9.9 4.9 24.0 0.39 9.5 10.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain PP_kinase_N PF13089.6 EMR69871.1 - 0.0039 17.5 0.0 0.55 10.6 0.0 2.6 2 0 0 2 2 2 2 Polyphosphate kinase N-terminal domain Pro_isomerase PF00160.21 EMR69872.1 - 2.5e-49 167.6 0.5 5.8e-49 166.4 0.3 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trm112p PF03966.16 EMR69873.1 - 4.8e-18 65.5 0.1 6e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 EMR69873.1 - 0.043 14.3 0.3 0.069 13.7 0.3 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Peptidase_M19 PF01244.21 EMR69874.1 - 2.6e-103 345.5 0.0 3.7e-103 345.1 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 EMR69874.1 - 0.043 13.6 0.0 0.064 13.0 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase Fcf1 PF04900.12 EMR69875.1 - 5.8e-34 116.4 0.1 1.5e-33 115.1 0.1 1.7 1 1 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EMR69875.1 - 4e-08 33.6 0.9 2.7e-05 24.5 0.0 2.9 3 0 0 3 3 3 2 PIN like domain BTB PF00651.31 EMR69876.1 - 0.00088 19.5 0.0 0.0042 17.3 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain BNR_2 PF13088.6 EMR69878.1 - 4.5e-10 39.3 0.0 8e-06 25.4 0.0 2.6 2 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EMR69878.1 - 4e-06 26.0 10.6 0.5 10.6 0.2 4.9 4 0 0 4 4 4 3 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 EMR69878.1 - 0.037 12.8 1.4 8.4 5.1 0.0 3.0 2 2 1 3 3 3 0 Sortilin, neurotensin receptor 3, DUF155 PF02582.14 EMR69879.1 - 1.2e-43 149.2 0.7 1.8e-43 148.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Asp PF00026.23 EMR69880.1 - 4.4e-107 358.2 0.2 5.2e-107 357.9 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR69880.1 - 6.2e-16 59.1 2.4 1.3e-13 51.6 2.3 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMR69880.1 - 1.9e-05 25.2 0.3 0.43 11.3 0.0 3.4 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EMR69880.1 - 0.00051 20.6 0.0 0.68 10.5 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EMR69880.1 - 0.00071 19.4 0.0 0.013 15.2 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SGL PF08450.12 EMR69881.1 - 0.15 11.6 0.0 10 5.6 0.0 2.1 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region SHMT PF00464.19 EMR69882.1 - 5.6e-208 690.4 0.0 6.5e-208 690.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EMR69882.1 - 1.4e-05 24.4 0.0 3.2e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMR69882.1 - 0.0014 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMR69882.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMR69882.1 - 0.17 10.3 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GST_N_3 PF13417.6 EMR69883.1 - 5.5e-21 74.8 0.1 1e-20 73.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMR69883.1 - 9.7e-19 67.4 0.1 6.4e-18 64.8 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMR69883.1 - 1.1e-11 44.9 0.1 2.1e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR69883.1 - 1.7e-08 34.3 0.2 4.1e-08 33.1 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMR69883.1 - 0.0015 19.1 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR69883.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EMR69883.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Mal_decarbox_Al PF16957.5 EMR69884.1 - 0.017 13.5 0.1 0.028 12.8 0.1 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter CBP_BcsF PF11120.8 EMR69884.1 - 0.48 10.6 3.8 1.9 8.7 3.3 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF p450 PF00067.22 EMR69885.1 - 1.6e-56 192.0 0.0 2e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 EMR69886.1 - 1.1e-86 291.1 0.0 2.2e-86 290.1 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR69886.1 - 9.4e-11 42.6 0.1 2.4e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.26 EMR69887.1 - 6.1e-23 81.2 0.1 1.1e-22 80.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR69887.1 - 9.9e-21 73.7 0.2 2.2e-20 72.5 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMR69887.1 - 0.0003 21.9 0.0 0.00052 21.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR69887.1 - 0.031 13.6 0.8 0.045 13.0 0.8 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EMR69887.1 - 0.083 12.3 0.2 0.16 11.4 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 EMR69887.1 - 0.16 11.3 0.7 0.28 10.5 0.4 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PRCC PF10253.9 EMR69888.1 - 4.9e-32 112.5 33.1 5.8e-30 105.7 33.1 3.2 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting HET PF06985.11 EMR69889.1 - 1.6e-08 35.0 3.4 3.2e-07 30.8 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 EMR69890.1 - 1.4e-32 113.1 37.6 7e-32 110.7 37.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF373 PF04123.13 EMR69890.1 - 0.0049 16.4 7.0 0.0049 16.4 7.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF373) DUF21 PF01595.20 EMR69890.1 - 0.41 10.3 10.9 0.46 10.2 0.9 3.8 3 1 0 3 3 3 0 Cyclin M transmembrane N-terminal domain HYR PF02494.16 EMR69891.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 HYR domain IMUP PF15761.5 EMR69892.1 - 0.43 11.3 5.0 4.7 8.0 2.6 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein Fungal_trans PF04082.18 EMR69895.1 - 6e-21 74.7 0.0 9.3e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 EMR69896.1 - 1.6e-91 306.8 37.1 1.1e-49 169.6 7.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMR69896.1 - 1.1e-66 223.6 0.0 4.8e-33 114.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMR69896.1 - 2.8e-16 59.6 0.5 1.8e-06 27.6 0.2 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMR69896.1 - 1.2e-07 32.1 1.2 0.03 14.6 0.1 4.1 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.6 EMR69896.1 - 1.2e-07 31.3 0.2 0.0088 15.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EMR69896.1 - 5e-06 26.4 5.3 0.0031 17.3 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EMR69896.1 - 7e-06 26.5 3.8 0.076 13.4 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMR69896.1 - 1.1e-05 25.4 0.0 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EMR69896.1 - 1.1e-05 26.0 0.0 0.089 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EMR69896.1 - 3e-05 24.0 2.1 0.0065 16.3 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EMR69896.1 - 5.5e-05 23.6 0.0 0.12 12.8 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 EMR69896.1 - 0.00012 22.0 0.2 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase ABC_ATPase PF09818.9 EMR69896.1 - 0.00054 18.9 1.6 0.014 14.2 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 EMR69896.1 - 0.00074 20.1 0.0 0.36 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMR69896.1 - 0.0014 18.2 1.5 1.8 8.1 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 EMR69896.1 - 0.0019 18.4 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMR69896.1 - 0.0023 17.9 0.2 1.2 9.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EMR69896.1 - 0.0037 17.4 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 EMR69896.1 - 0.0041 17.2 0.1 1.4 9.0 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EMR69896.1 - 0.01 15.1 0.2 1.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 EMR69896.1 - 0.013 15.3 0.0 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EMR69896.1 - 0.013 15.2 0.0 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EMR69896.1 - 0.037 13.7 2.9 4.6 6.8 0.0 3.3 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 EMR69896.1 - 0.037 14.2 6.3 3.8 7.8 0.1 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EMR69896.1 - 0.056 13.0 0.1 5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EMR69896.1 - 0.063 13.0 0.1 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 EMR69896.1 - 0.14 11.8 0.1 2.6 7.6 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2238 PF09997.9 EMR69896.1 - 1.1 9.1 15.8 2.3 8.0 0.9 3.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) Apolipoprotein PF01442.18 EMR69897.1 - 0.00035 20.5 14.1 0.0025 17.7 11.8 3.0 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 EMR69897.1 - 0.0025 18.1 4.9 17 5.8 0.0 4.6 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) FAM184 PF15665.5 EMR69897.1 - 0.0047 16.7 12.9 0.27 11.0 0.0 3.5 3 1 1 4 4 4 2 Family with sequence similarity 184, A and B Prominin PF05478.11 EMR69897.1 - 0.023 12.7 5.1 0.21 9.5 0.3 2.4 1 1 0 2 2 2 0 Prominin ApoO PF09769.9 EMR69897.1 - 0.036 14.0 2.5 5 7.1 0.2 3.6 4 1 0 4 4 4 0 Apolipoprotein O HBS1_N PF08938.10 EMR69897.1 - 0.062 13.6 2.7 0.27 11.6 0.6 2.7 2 0 0 2 2 2 0 HBS1 N-terminus Globin PF00042.22 EMR69897.1 - 0.075 13.6 0.7 4.4 7.9 0.1 3.5 2 1 1 3 3 3 0 Globin DUF4378 PF14309.6 EMR69897.1 - 0.096 13.1 1.7 3.5 8.0 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4378) GCR1_C PF12550.8 EMR69897.1 - 0.11 12.9 0.5 0.58 10.5 0.1 2.5 3 0 0 3 3 3 0 Transcriptional activator of glycolytic enzymes XH PF03469.14 EMR69897.1 - 0.34 10.8 8.2 0.44 10.5 0.0 3.6 3 1 1 4 4 4 0 XH domain DUF3223 PF11523.8 EMR69897.1 - 0.37 11.7 2.6 0.82 10.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3223) DOG1 PF14144.6 EMR69897.1 - 0.48 10.7 1.3 3 8.1 0.5 2.5 2 0 0 2 2 2 0 Seed dormancy control HisKA_3 PF07730.13 EMR69897.1 - 1.2 9.7 3.9 16 6.1 0.3 4.1 4 1 0 4 4 4 0 Histidine kinase DUF883 PF05957.13 EMR69897.1 - 1.3 9.7 11.4 17 6.1 1.6 5.1 3 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 EMR69897.1 - 2.3 8.4 8.3 39 4.4 1.0 3.6 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family SnoaL_2 PF12680.7 EMR69898.1 - 0.014 16.0 0.6 0.098 13.3 0.6 2.2 1 1 0 1 1 1 0 SnoaL-like domain RsbU_N PF08673.10 EMR69898.1 - 0.071 13.2 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Pyr_redox_2 PF07992.14 EMR69899.1 - 3.4e-20 72.5 0.0 4.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR69899.1 - 1.3e-13 51.3 0.0 1.3e-09 38.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR69899.1 - 0.0081 15.3 0.1 0.13 11.4 0.2 2.3 1 1 2 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMR69899.1 - 0.016 14.5 1.0 1.4 8.1 0.5 2.4 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EMR69899.1 - 0.036 14.5 0.0 0.16 12.5 0.0 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EMR69899.1 - 0.046 12.8 0.1 0.081 12.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMR69899.1 - 0.052 13.5 0.1 2.5 8.1 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 EMR69899.1 - 0.079 12.5 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR69899.1 - 0.16 12.2 0.0 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_18 PF00704.28 EMR69900.1 - 1.1e-20 74.6 0.8 8.2e-20 71.8 0.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 MA3 PF02847.17 EMR69901.1 - 2.1e-25 88.9 0.0 7.2e-25 87.2 0.0 2.0 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EMR69901.1 - 1.5e-13 50.9 0.4 1.5e-13 50.9 0.4 2.1 2 1 0 2 2 2 1 MIF4G domain Cnd1 PF12717.7 EMR69901.1 - 0.15 12.1 1.8 0.39 10.8 1.8 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Vfa1 PF08432.10 EMR69901.1 - 0.44 10.9 3.7 1.1 9.6 3.7 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 EMR69901.1 - 0.66 9.6 5.5 1.5 8.5 5.5 1.5 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 EMR69901.1 - 0.68 9.2 10.5 1.5 8.1 10.5 1.5 1 0 0 1 1 1 0 BUD22 DPM2 PF07297.12 EMR69902.1 - 1.2e-30 105.6 2.2 1.4e-30 105.4 2.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4229 PF14012.6 EMR69902.1 - 0.00057 19.9 0.6 0.00057 19.9 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) PIG-P PF08510.12 EMR69902.1 - 0.0016 18.3 1.9 0.002 18.1 1.9 1.1 1 0 0 1 1 1 1 PIG-P COX14 PF14880.6 EMR69902.1 - 0.0074 16.1 3.3 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF4013 PF13197.6 EMR69902.1 - 0.041 13.7 5.3 0.049 13.5 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) LapA_dom PF06305.11 EMR69902.1 - 0.041 13.7 0.4 0.041 13.7 0.4 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4719 PF15843.5 EMR69902.1 - 0.094 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Acetyltransf_8 PF13523.6 EMR69903.1 - 3.5e-45 153.3 1.0 5.1e-45 152.7 1.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMR69903.1 - 0.094 13.4 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Kelch_4 PF13418.6 EMR69904.1 - 3.1e-17 62.3 8.4 4.7e-05 23.3 0.2 4.6 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EMR69904.1 - 5.8e-17 61.5 11.2 3.9e-08 33.4 0.1 4.8 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EMR69904.1 - 5.3e-15 55.0 0.8 4e-08 33.1 0.0 3.7 4 0 0 4 4 4 3 Kelch motif DUF4110 PF13422.6 EMR69904.1 - 3.8e-13 49.3 0.6 3.8e-13 49.3 0.6 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 EMR69904.1 - 1.1e-10 41.4 3.2 0.00082 19.6 0.1 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EMR69904.1 - 5.4e-08 32.5 6.2 0.00026 20.8 0.1 4.8 3 2 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 EMR69904.1 - 7.8e-08 31.8 7.6 2.1e-05 24.0 0.0 4.3 5 1 0 5 5 5 2 Kelch motif Sporozoite_P67 PF05642.11 EMR69904.1 - 1.4 6.9 11.9 2.6 6.0 11.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIF_alpha PF05793.12 EMR69904.1 - 2.2 6.8 32.5 2.2 6.8 15.1 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Goodbye PF17109.5 EMR69905.1 - 1e-13 51.8 0.0 2.7e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 EMR69905.1 - 0.00018 22.0 0.0 0.00091 19.6 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain TPR_16 PF13432.6 EMR69905.1 - 0.0019 18.8 7.8 0.0063 17.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR69905.1 - 0.0092 16.0 6.7 12 6.3 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.6 EMR69905.1 - 0.029 14.6 0.0 0.28 11.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EMR69905.1 - 0.053 13.8 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain MatP PF06303.12 EMR69906.1 - 0.11 13.1 0.1 0.2 12.2 0.1 1.4 1 0 0 1 1 1 0 MatP N-terminal domain bZIP_1 PF00170.21 EMR69907.1 - 0.075 13.1 7.4 0.36 10.9 7.4 2.1 1 1 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 EMR69907.1 - 0.18 12.5 0.1 0.94 10.1 0.0 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF2205 PF10224.9 EMR69907.1 - 0.62 10.1 3.3 24 5.0 0.0 2.3 2 0 0 2 2 2 0 Short coiled-coil protein TFIIA PF03153.13 EMR69907.1 - 2.2 8.2 15.5 0.78 9.7 9.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3546 PF12066.8 EMR69908.1 - 6.6e-34 116.4 3.1 6.6e-34 116.4 3.1 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EMR69908.1 - 4.1e-12 45.7 0.1 1.1e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EMR69908.1 - 5.5e-10 39.9 10.4 4.8e-09 36.9 10.3 2.6 1 1 0 1 1 1 1 Arsenite-resistance protein 2 CD99L2 PF12301.8 EMR69908.1 - 0.15 12.3 2.6 0.84 9.9 2.6 2.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 PEP-utilisers_N PF05524.13 EMR69908.1 - 0.98 9.6 6.4 1.5 9.0 1.8 2.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal SUR7 PF06687.12 EMR69909.1 - 3e-26 92.4 0.2 3.6e-26 92.1 0.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EMR69909.1 - 9.6e-05 22.4 1.0 9.6e-05 22.4 1.0 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF1218 PF06749.12 EMR69909.1 - 0.65 10.6 0.1 0.65 10.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Tetraspanin PF00335.20 EMR69909.1 - 2.9 7.5 0.0 2.9 7.5 0.0 2.6 2 1 1 3 3 3 0 Tetraspanin family Hemerythrin PF01814.23 EMR69910.1 - 0.056 14.1 1.0 1.3 9.6 0.1 2.1 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain FAM76 PF16046.5 EMR69910.1 - 0.2 11.0 0.4 0.23 10.8 0.4 1.1 1 0 0 1 1 1 0 FAM76 protein Dioxygenase_C PF00775.21 EMR69911.1 - 1.9e-09 37.2 0.0 3.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase R3H PF01424.22 EMR69912.1 - 2e-14 53.3 0.2 3.3e-14 52.6 0.2 1.4 1 0 0 1 1 1 1 R3H domain F-box-like_2 PF13013.6 EMR69913.1 - 0.014 15.4 0.0 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain Mito_carr PF00153.27 EMR69914.1 - 6.7e-61 202.2 0.2 4.1e-19 68.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_6 PF08036.11 EMR69914.1 - 0.22 11.6 1.0 8.5 6.5 0.4 2.4 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide WSC PF01822.19 EMR69915.1 - 1e-53 179.4 39.7 4.8e-19 68.3 6.9 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.11 EMR69915.1 - 4.1e-25 88.4 0.0 1.3e-24 86.7 0.0 1.8 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EMR69915.1 - 1.5e-21 76.5 0.1 3e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 EMR69915.1 - 0.009 16.0 0.5 7.5 6.7 0.0 4.1 4 0 0 4 4 4 1 Kelch motif TspO_MBR PF03073.15 EMR69916.1 - 5.4e-39 133.3 7.7 7.4e-39 132.9 7.7 1.2 1 0 0 1 1 1 1 TspO/MBR family MscL PF01741.18 EMR69917.1 - 7.2e-16 58.6 1.5 9.3e-16 58.2 1.5 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.15 EMR69917.1 - 0.029 14.4 0.1 0.049 13.7 0.1 1.3 1 0 0 1 1 1 0 BED zinc finger RTA1 PF04479.13 EMR69918.1 - 6.5e-41 140.2 4.8 9e-41 139.8 4.8 1.2 1 0 0 1 1 1 1 RTA1 like protein RRN3 PF05327.11 EMR69919.1 - 8.6e-166 552.8 0.2 8.6e-166 552.8 0.2 1.4 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 TetR_C_30 PF17939.1 EMR69919.1 - 0.081 13.2 0.3 0.49 10.6 0.0 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Sigma70_ner PF04546.13 EMR69919.1 - 5.4 6.8 16.0 0.27 11.1 2.6 3.4 3 0 0 3 3 3 0 Sigma-70, non-essential region zf-HIT PF04438.16 EMR69920.1 - 2.8e-09 36.7 4.4 4.1e-09 36.1 4.4 1.3 1 0 0 1 1 1 1 HIT zinc finger Ribonuc_L-PSP PF01042.21 EMR69922.1 - 7.4e-24 84.1 0.0 8.8e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP BaffR-Tall_bind PF09256.10 EMR69923.1 - 0.051 13.3 0.5 0.093 12.5 0.5 1.3 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding AAA PF00004.29 EMR69924.1 - 8.9e-37 126.5 0.0 7.5e-36 123.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMR69924.1 - 5.1e-11 42.2 0.0 1.3e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EMR69924.1 - 9.5e-08 32.6 0.1 0.0008 19.8 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 EMR69924.1 - 7.4e-06 25.8 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR69924.1 - 1.5e-05 25.3 0.4 0.011 16.1 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMR69924.1 - 0.0006 19.9 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMR69924.1 - 0.00093 19.4 0.0 0.0026 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMR69924.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EMR69924.1 - 0.0016 18.1 1.4 0.83 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 EMR69924.1 - 0.0018 18.4 0.0 0.0065 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EMR69924.1 - 0.0022 17.2 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 EMR69924.1 - 0.0031 17.9 0.3 0.021 15.2 0.2 2.4 2 1 0 2 2 2 1 RNA helicase TsaE PF02367.17 EMR69924.1 - 0.0034 17.4 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EMR69924.1 - 0.0037 17.8 0.0 0.012 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EMR69924.1 - 0.0039 16.6 0.0 0.2 11.1 0.0 2.4 1 1 1 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 EMR69924.1 - 0.0062 16.5 0.7 0.026 14.5 0.2 2.4 3 1 0 3 3 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMR69924.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 EMR69924.1 - 0.015 15.7 1.3 0.13 12.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EMR69924.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMR69924.1 - 0.019 15.2 0.1 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EMR69924.1 - 0.025 14.3 0.4 0.1 12.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMR69924.1 - 0.046 13.6 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 Rad17 P-loop domain DUF815 PF05673.13 EMR69924.1 - 0.046 12.9 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EMR69924.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EMR69924.1 - 0.063 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EMR69924.1 - 0.086 12.8 0.1 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 NACHT domain IPT PF01745.16 EMR69924.1 - 0.1 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Isopentenyl transferase WSC PF01822.19 EMR69925.1 - 1.2e-15 57.5 6.5 1.6e-15 57.0 6.5 1.2 1 0 0 1 1 1 1 WSC domain DUF1772 PF08592.11 EMR69926.1 - 0.001 19.4 0.8 0.0014 18.9 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) zf-C2H2 PF00096.26 EMR69928.1 - 0.0012 19.2 5.1 0.0045 17.4 0.4 3.0 3 1 0 3 3 3 1 Zinc finger, C2H2 type COX4 PF02936.14 EMR69929.1 - 7.1e-47 158.9 0.2 8.4e-47 158.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 EMR69929.1 - 0.045 14.1 0.3 0.087 13.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) PsbN PF02468.15 EMR69929.1 - 0.71 9.8 2.1 12 5.8 0.1 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF2052 PF09747.9 EMR69933.1 - 0.14 12.3 10.7 0.16 12.1 7.6 2.3 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Orthopox_F7 PF05813.12 EMR69934.1 - 0.003 17.6 0.7 0.0041 17.2 0.7 1.2 1 0 0 1 1 1 1 Orthopoxvirus F7 protein Sugar_tr PF00083.24 EMR69935.1 - 7.6e-129 430.5 25.1 8.7e-129 430.3 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR69935.1 - 4e-21 75.3 55.5 2e-18 66.5 30.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mus7 PF09462.10 EMR69936.1 - 1e-17 64.3 0.0 1.3e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family DUF2153 PF09921.9 EMR69936.1 - 0.11 12.4 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) SprB PF13573.6 EMR69936.1 - 0.37 10.6 2.6 1.5 8.6 0.5 2.4 2 0 0 2 2 2 0 SprB repeat Nop14 PF04147.12 EMR69937.1 - 0.13 10.5 15.4 0.13 10.5 15.4 1.0 1 0 0 1 1 1 0 Nop14-like family AAA_23 PF13476.6 EMR69937.1 - 0.17 12.3 10.4 0.19 12.2 10.4 1.2 1 0 0 1 1 1 0 AAA domain ESM4 PF15952.5 EMR69937.1 - 0.25 11.8 4.9 0.29 11.5 4.9 1.1 1 0 0 1 1 1 0 Enhancer of split M4 family ABC_trans_N PF14510.6 EMR69937.1 - 0.27 11.9 6.2 1.3 9.6 6.3 2.0 1 1 0 1 1 1 0 ABC-transporter N-terminal CDC45 PF02724.14 EMR69937.1 - 0.31 9.3 9.3 0.27 9.5 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein CSG2 PF16965.5 EMR69937.1 - 0.66 8.9 1.5 0.73 8.7 1.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator tRNA_bind_2 PF13725.6 EMR69937.1 - 0.72 9.5 9.0 0.94 9.1 9.0 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain RPA43_OB PF17875.1 EMR69937.1 - 0.74 10.4 5.9 1 10.0 5.9 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I AA_permease_N PF08403.10 EMR69937.1 - 1 8.9 5.1 0.73 9.4 2.9 1.8 1 1 1 2 2 2 0 Amino acid permease N-terminal Zip PF02535.22 EMR69937.1 - 1.1 8.5 2.7 1.3 8.2 2.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Merozoite_SPAM PF07133.11 EMR69937.1 - 3.8 7.5 36.7 4.6 7.2 36.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 EMR69937.1 - 4.6 6.6 19.5 5.2 6.4 19.5 1.0 1 0 0 1 1 1 0 SDA1 Connexin PF00029.19 EMR69937.1 - 5 6.8 4.5 5.7 6.6 4.5 1.1 1 0 0 1 1 1 0 Connexin Usp PF00582.26 EMR69937.1 - 5.1 7.6 7.6 7.3 7.1 7.6 1.3 1 0 0 1 1 1 0 Universal stress protein family FancD2 PF14631.6 EMR69937.1 - 7.9 3.7 7.7 8.6 3.6 7.7 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease ABC_tran PF00005.27 EMR69939.1 - 7.1e-52 175.6 0.0 3.3e-28 98.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR69939.1 - 3.6e-33 115.4 17.2 1.5e-19 70.8 8.1 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EMR69939.1 - 9.2e-11 41.6 1.7 0.081 12.4 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMR69939.1 - 1.2e-07 31.4 1.5 0.0052 16.5 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EMR69939.1 - 1.4e-07 32.3 0.1 0.00013 22.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMR69939.1 - 3.6e-07 30.3 0.2 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EMR69939.1 - 1.1e-06 28.4 0.0 0.046 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMR69939.1 - 2.4e-06 28.0 0.0 0.028 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EMR69939.1 - 3.5e-06 27.3 2.3 0.0015 18.7 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 EMR69939.1 - 2e-05 24.7 0.3 0.037 14.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EMR69939.1 - 4.5e-05 23.4 0.9 2.7 7.7 0.2 3.8 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 EMR69939.1 - 4.8e-05 22.7 1.5 2.5 7.2 0.1 4.1 4 0 0 4 4 4 1 NB-ARC domain AAA_22 PF13401.6 EMR69939.1 - 7.8e-05 23.0 0.8 0.81 10.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 EMR69939.1 - 8.9e-05 22.6 3.9 0.041 13.9 0.0 2.7 3 0 0 3 3 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 EMR69939.1 - 0.00019 20.9 0.3 0.25 10.7 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.12 EMR69939.1 - 0.00092 19.2 1.0 0.82 9.6 0.2 2.6 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.6 EMR69939.1 - 0.0021 18.2 1.2 1.3 9.3 0.0 3.3 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit Viral_helicase1 PF01443.18 EMR69939.1 - 0.0024 17.7 0.0 3 7.5 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_15 PF13175.6 EMR69939.1 - 0.0026 17.5 0.1 0.21 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EMR69939.1 - 0.0027 17.7 1.0 6.6 6.7 0.0 4.3 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EMR69939.1 - 0.0028 16.8 0.5 1.5 7.8 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein Septin PF00735.18 EMR69939.1 - 0.0037 16.6 0.0 2.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Septin AAA_33 PF13671.6 EMR69939.1 - 0.0037 17.4 0.0 4.2 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 EMR69939.1 - 0.0055 16.0 0.9 2 7.7 0.0 2.4 2 0 0 2 2 2 1 AIG1 family AAA_7 PF12775.7 EMR69939.1 - 0.0067 16.0 0.4 1.8 8.1 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region Pox_A32 PF04665.12 EMR69939.1 - 0.0073 15.8 1.9 0.57 9.6 0.1 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein ATP_bind_1 PF03029.17 EMR69939.1 - 0.0078 16.0 1.5 3.9 7.2 0.1 3.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Roc PF08477.13 EMR69939.1 - 0.027 14.7 0.2 17 5.6 0.0 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EMR69939.1 - 0.034 13.9 0.1 10 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMR69939.1 - 0.072 12.8 0.1 7.8 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EMR69939.1 - 0.08 12.5 2.8 6.5 6.3 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EMR69939.1 - 0.086 13.2 0.1 14 6.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DEAD PF00270.29 EMR69939.1 - 0.087 12.6 0.0 7.4 6.3 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_14 PF13173.6 EMR69939.1 - 0.11 12.6 0.0 23 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EMR69939.1 - 0.12 12.1 0.4 22 4.7 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EMR69939.1 - 0.16 11.2 0.1 6 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 EMR69939.1 - 0.18 11.0 0.1 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EMR69939.1 - 0.54 10.1 2.1 12 5.8 0.0 3.0 3 0 0 3 3 2 0 NTPase Glyco_hydro_43 PF04616.14 EMR69940.1 - 7.1e-22 78.0 9.9 5.4e-08 32.5 3.6 3.6 3 1 1 4 4 4 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EMR69940.1 - 0.0059 16.2 0.4 0.067 12.8 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain SOCS PF12610.8 EMR69943.1 - 0.062 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Suppressor of cytokine signalling HAD PF12710.7 EMR69944.1 - 0.016 15.7 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase SKA2 PF16740.5 EMR69945.1 - 0.0042 16.8 0.1 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 Glyco_hydro_20 PF00728.22 EMR69946.1 - 2.8e-21 76.3 0.1 1e-16 61.3 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain RIO1 PF01163.22 EMR69947.1 - 6.1e-67 224.9 1.1 6.9e-67 224.7 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EMR69947.1 - 0.0013 18.7 0.1 2.2 8.1 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EMR69947.1 - 0.0051 16.2 0.1 0.23 10.8 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family rRNA_processing PF08524.11 EMR69947.1 - 2.5 8.1 18.7 2.8 7.9 0.5 2.4 2 0 0 2 2 2 0 rRNA processing YL1 PF05764.13 EMR69947.1 - 7.8 6.5 37.3 2.9 8.0 14.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein DNA_pol_phi PF04931.13 EMR69948.1 - 1.7e-196 654.8 38.5 4.4e-196 653.4 38.5 1.6 1 1 0 1 1 1 1 DNA polymerase phi RTP1_C1 PF10363.9 EMR69948.1 - 0.00044 20.4 0.1 0.17 12.1 0.0 3.3 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Nop14 PF04147.12 EMR69948.1 - 0.62 8.2 24.9 1.6 6.8 24.9 1.8 1 0 0 1 1 1 0 Nop14-like family Duffy_binding PF05424.11 EMR69948.1 - 3.7 7.5 9.5 15 5.6 0.1 2.7 2 0 0 2 2 2 0 Duffy binding domain BUD22 PF09073.10 EMR69948.1 - 8.8 5.5 36.1 0.52 9.6 27.2 2.4 2 0 0 2 2 2 0 BUD22 DHDPS PF00701.22 EMR69949.1 - 1.4e-49 168.4 0.0 1.7e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF326 PF03860.16 EMR69949.1 - 2.3 8.3 4.1 11 6.1 0.9 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) Proteasome PF00227.26 EMR69951.1 - 2.2e-44 151.3 0.1 6.2e-31 107.4 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EMR69951.1 - 7e-12 44.8 0.0 1.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ATG_C PF09333.11 EMR69952.1 - 0.0019 18.5 0.0 0.0065 16.8 0.0 1.9 1 1 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EMR69952.1 - 0.047 13.5 0.8 0.059 13.2 0.1 1.4 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal CwfJ_C_2 PF04676.14 EMR69953.1 - 7e-13 49.3 0.2 1.6e-12 48.2 0.2 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EMR69953.1 - 1.4e-09 37.9 0.0 2.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rhodanese PF00581.20 EMR69954.1 - 6.5e-13 49.1 0.0 1.2e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Chromo PF00385.24 EMR69956.1 - 6.4e-09 35.6 0.9 5.9e-08 32.5 0.4 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SGS PF05002.15 EMR69956.1 - 0.047 13.8 0.7 0.17 12.0 0.7 1.9 1 0 0 1 1 1 0 SGS domain NOA36 PF06524.12 EMR69956.1 - 0.82 8.9 7.6 0.93 8.8 1.9 2.2 2 0 0 2 2 2 0 NOA36 protein PIN_3 PF13470.6 EMR69956.1 - 4.1 8.2 5.5 51 4.7 5.5 2.3 1 1 0 1 1 1 0 PIN domain Acetyltransf_1 PF00583.25 EMR69957.1 - 5e-11 42.9 0.0 6.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMR69957.1 - 7.3e-08 32.3 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EMR69957.1 - 8.1e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR69957.1 - 1.7e-07 31.6 0.0 2.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR69957.1 - 6.6e-06 26.2 0.0 0.00021 21.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR69957.1 - 0.00012 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Sporozoite_P67 PF05642.11 EMR69957.1 - 0.08 11.0 0.6 0.099 10.7 0.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DRIM PF07539.12 EMR69958.1 - 3.1e-193 643.5 1.3 3.1e-193 643.5 1.3 3.0 4 0 0 4 4 4 1 Down-regulated in metastasis DUF3385 PF11865.8 EMR69958.1 - 0.0024 17.8 1.4 2.3 8.1 0.0 4.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 EMR69958.1 - 0.0044 17.6 1.9 3.1 8.4 0.1 4.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 EMR69958.1 - 0.1 12.5 12.3 12 5.7 0.1 6.5 7 0 0 7 7 7 0 Guanine nucleotide exchange factor in Golgi transport N-terminal MMS22L_C PF14911.6 EMR69958.1 - 0.13 11.4 5.0 0.33 10.0 0.2 4.0 4 1 1 5 5 5 0 S-phase genomic integrity recombination mediator, C-terminal HEAT PF02985.22 EMR69958.1 - 3.4 8.2 18.4 8.1 7.0 0.0 8.4 12 0 0 12 12 12 0 HEAT repeat Ricin_B_lectin PF00652.22 EMR69959.1 - 9.4e-16 58.2 0.9 5e-09 36.5 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EMR69959.1 - 3.5e-12 46.9 2.9 7.9e-07 29.7 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF3739 PF12545.8 EMR69959.1 - 0.042 14.3 0.3 2.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Filamentous haemagglutinin family outer membrane protein Amidoligase_2 PF12224.8 EMR69960.1 - 2.8e-15 56.7 0.0 1.6e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme DAO PF01266.24 EMR69961.1 - 1.8e-35 123.2 0.0 2.1e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR69961.1 - 3.5e-06 27.2 0.0 8.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR69961.1 - 7e-05 22.2 0.0 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR69961.1 - 0.00012 21.5 0.0 0.042 13.1 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EMR69961.1 - 0.0004 19.6 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EMR69961.1 - 0.0016 17.7 0.0 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EMR69961.1 - 0.0021 18.6 0.0 0.015 15.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CgtA PF06306.11 EMR69961.1 - 0.0042 16.6 0.0 0.65 9.4 0.0 2.1 2 0 0 2 2 2 1 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) Pyr_redox_3 PF13738.6 EMR69961.1 - 0.0046 16.3 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR69961.1 - 0.0096 15.2 0.0 0.024 13.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EMR69961.1 - 0.011 14.4 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 EMR69961.1 - 0.033 14.6 0.0 0.075 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 EMR69961.1 - 0.04 12.8 0.0 0.086 11.7 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 EMR69961.1 - 0.044 14.1 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Glu_dehyd_C PF16912.5 EMR69961.1 - 0.086 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus GIDA PF01134.22 EMR69961.1 - 0.098 11.7 0.1 12 4.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GST_N PF02798.20 EMR69962.1 - 2.6e-10 40.5 0.0 5.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR69962.1 - 3.9e-08 33.2 0.0 7.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR69962.1 - 3.8e-07 30.2 0.0 8.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR69962.1 - 9.2e-07 29.1 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR69962.1 - 2.3e-06 27.9 0.0 4.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR69962.1 - 1.7e-05 24.9 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Drf_GBD PF06371.13 EMR69963.1 - 1.5e-13 50.7 0.9 1.2e-11 44.5 0.9 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF755 PF05501.11 EMR69963.1 - 0.015 15.6 1.6 0.015 15.6 1.6 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF755) MFS_1 PF07690.16 EMR69964.1 - 2e-08 33.5 20.5 0.00013 21.0 0.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_79C PF16862.5 EMR69965.1 - 4.9e-21 75.5 0.1 1.1e-20 74.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain UCR_hinge PF02320.16 EMR69966.1 - 1.1e-28 99.2 9.7 2.5e-28 98.1 9.7 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Ribosomal_60s PF00428.19 EMR69966.1 - 0.0012 19.4 7.3 0.0026 18.3 7.3 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein PTPRCAP PF15713.5 EMR69966.1 - 2.3 8.5 23.9 0.052 13.8 15.5 2.0 1 1 1 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Nexin_C PF08628.12 EMR69967.1 - 2.8e-28 98.7 0.0 8.7e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EMR69967.1 - 1.6e-20 73.2 0.5 3.2e-20 72.2 0.5 1.5 1 0 0 1 1 1 1 PX domain Mod_r PF07200.13 EMR69967.1 - 0.28 11.3 7.6 0.32 11.1 3.0 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MFS_1 PF07690.16 EMR69968.1 - 2.4e-24 85.9 35.4 5.2e-24 84.8 35.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EMR69969.1 - 8.6e-19 67.7 39.4 8.6e-19 67.7 39.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Gate PF07670.14 EMR69969.1 - 1.2 9.4 6.7 4.1 7.7 1.9 2.9 2 1 0 2 2 2 0 Nucleoside recognition DUF3446 PF11928.8 EMR69970.1 - 0.24 11.7 10.7 0.66 10.3 6.4 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain RRM_1 PF00076.22 EMR69971.1 - 1.9e-22 78.8 0.0 1.6e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMR69971.1 - 0.0047 16.8 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif MFS_1 PF07690.16 EMR69972.1 - 1.4e-21 76.8 24.5 9.3e-17 61.0 21.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_4 PF02390.17 EMR69973.1 - 3.9e-58 195.7 0.0 6e-58 195.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EMR69973.1 - 0.00078 20.1 0.0 0.0021 18.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EMR69973.1 - 0.002 17.7 0.0 0.0089 15.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EMR69973.1 - 0.015 16.1 0.0 0.038 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EMR69973.1 - 0.063 13.9 0.0 0.3 11.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EMR69973.1 - 0.18 11.6 0.1 0.36 10.6 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Homoserine_dh PF00742.19 EMR69974.1 - 2.3e-52 177.4 0.0 3e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EMR69974.1 - 7.8e-19 68.5 0.0 1.2e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PglD_N PF17836.1 EMR69974.1 - 0.098 13.3 0.3 0.55 10.9 0.0 2.5 2 0 0 2 2 2 0 PglD N-terminal domain RNA_helicase PF00910.22 EMR69974.1 - 0.11 12.8 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IGPS PF00218.21 EMR69974.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase DUF4078 PF13300.6 EMR69975.1 - 4.7e-05 23.6 0.0 4.7e-05 23.6 0.0 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) DUF4820 PF16091.5 EMR69975.1 - 0.0043 16.5 2.3 0.0043 16.5 2.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4820) Cwf_Cwc_15 PF04889.12 EMR69975.1 - 0.0094 15.7 19.9 0.21 11.3 19.6 2.1 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein WRNPLPNID PF15017.6 EMR69975.1 - 5.1 8.0 12.0 6.4 7.7 3.1 2.7 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Hydantoinase_B PF02538.14 EMR69976.1 - 3.8e-202 672.3 0.2 8e-202 671.2 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMR69976.1 - 5.8e-98 327.7 0.8 8.1e-98 327.3 0.1 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMR69976.1 - 7e-63 211.5 0.5 1.5e-61 207.2 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region AP_endonuc_2 PF01261.24 EMR69976.1 - 0.095 12.1 0.0 18 4.7 0.0 2.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Proteasome_A_N PF10584.9 EMR69976.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature PrpR_N PF06506.11 EMR69976.1 - 4.5 6.8 5.4 4.4 6.8 0.1 3.0 4 0 0 4 4 4 0 Propionate catabolism activator Acyltransferase PF01553.21 EMR69977.1 - 4.7e-09 36.0 0.0 5.4e-08 32.5 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase DUF2263 PF10021.9 EMR69978.1 - 1.5e-18 67.5 0.2 1.1e-17 64.7 0.2 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Endostatin PF06482.11 EMR69978.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin BBE PF08031.12 EMR69979.1 - 0.0046 17.0 0.1 0.0091 16.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_24 PF13578.6 EMR69981.1 - 1.6e-12 48.4 0.0 2.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EMR69981.1 - 3e-05 23.3 0.0 5e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase GCD14 PF08704.10 EMR69981.1 - 0.026 14.2 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CmcI PF04989.12 EMR69981.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase Tri3 PF07428.11 EMR69982.1 - 6.6e-07 28.6 0.1 0.0062 15.5 0.0 2.1 2 0 0 2 2 2 2 15-O-acetyltransferase Tri3 PapA_C PF16911.5 EMR69982.1 - 0.06 13.4 0.1 0.34 11.0 0.1 2.2 1 1 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus SGL PF08450.12 EMR69983.1 - 3.5e-34 118.5 0.1 4.6e-34 118.1 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EMR69983.1 - 0.00034 20.7 0.0 0.5 10.5 0.0 2.5 2 0 0 2 2 2 2 Strictosidine synthase PQQ_3 PF13570.6 EMR69983.1 - 0.12 12.9 0.2 2.5 8.7 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain Epimerase PF01370.21 EMR69984.1 - 4e-12 46.1 0.7 6.2e-11 42.2 0.7 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR69984.1 - 1.6e-07 31.4 0.3 6.5e-07 29.4 0.1 1.9 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMR69984.1 - 0.00039 20.1 0.2 0.00058 19.5 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EMR69984.1 - 0.00068 18.7 0.3 0.0012 17.9 0.1 1.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMR69984.1 - 0.006 15.8 0.3 0.058 12.6 0.1 2.2 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EMR69984.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 EMR69984.1 - 0.013 15.6 0.3 0.064 13.3 0.1 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMR69984.1 - 0.019 15.2 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EMR69984.1 - 0.15 11.5 0.1 0.91 8.9 0.1 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Amidohydro_2 PF04909.14 EMR69985.1 - 2.8e-31 109.4 0.2 3.2e-31 109.2 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.25 EMR69986.1 - 1e-15 57.7 0.0 1.3e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69986.1 - 1.6e-12 47.5 0.0 2.1e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase COesterase PF00135.28 EMR69987.1 - 3.1e-68 230.9 0.0 1.9e-50 172.2 0.3 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR69987.1 - 3.5e-06 27.0 0.3 3.3e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold PsbN PF02468.15 EMR69987.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) ADH_zinc_N PF00107.26 EMR69988.1 - 1.2e-18 67.3 1.5 2.2e-18 66.5 1.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR69988.1 - 1.1e-10 41.3 0.7 1.1e-10 41.3 0.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMR69988.1 - 1.3e-05 26.3 0.1 0.0012 19.9 0.1 2.5 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR69988.1 - 5.5e-05 22.6 1.7 8.1e-05 22.0 1.7 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EMR69988.1 - 0.00093 18.7 0.5 0.0017 17.9 0.5 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Prot_ATP_ID_OB PF16450.5 EMR69988.1 - 0.0046 16.9 0.9 0.066 13.2 0.0 2.9 3 0 0 3 3 3 1 Proteasomal ATPase OB C-terminal domain zf-CXXC PF02008.20 EMR69988.1 - 0.015 15.3 2.9 0.026 14.5 2.9 1.3 1 0 0 1 1 1 0 CXXC zinc finger domain IlvN PF07991.12 EMR69988.1 - 0.019 14.5 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain OapA PF04225.12 EMR69988.1 - 0.043 13.9 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain ThiF PF00899.21 EMR69988.1 - 0.054 12.8 0.3 0.092 12.1 0.3 1.3 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 EMR69988.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amidohydro_3 PF07969.11 EMR69989.1 - 7.6e-49 167.4 0.0 1e-48 167.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EMR69989.1 - 0.0051 16.2 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family FAD_binding_3 PF01494.19 EMR69990.1 - 6.7e-41 140.7 0.0 8.4e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMR69990.1 - 2.9e-17 63.2 0.0 3.1e-14 53.3 0.0 2.3 1 1 1 2 2 2 2 Phenol hydroxylase, C-terminal dimerisation domain KR PF08659.10 EMR69991.1 - 2.5e-38 131.8 0.4 4.7e-38 130.9 0.0 1.6 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EMR69991.1 - 1.1e-13 51.3 0.0 3e-13 49.9 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR69991.1 - 1.5e-08 35.8 0.0 3.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EMR69991.1 - 3.9e-06 27.1 0.2 9.5e-06 25.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EMR69991.1 - 0.00016 21.5 0.1 0.00037 20.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EMR69991.1 - 0.0016 17.9 0.1 0.0069 15.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR69991.1 - 0.002 17.8 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HAD_2 PF13419.6 EMR69991.1 - 0.007 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Epimerase PF01370.21 EMR69991.1 - 0.09 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aldedh PF00171.22 EMR69992.1 - 1e-107 360.5 0.1 1.3e-107 360.2 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-CCCH_2 PF14608.6 EMR69993.1 - 4.5e-12 46.0 51.1 2.4e-06 27.8 12.1 5.4 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EMR69993.1 - 0.0096 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.24 EMR69994.1 - 6.6e-17 61.9 0.0 9.3e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR69994.1 - 3.6e-12 46.3 1.0 9.5e-12 45.0 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR69994.1 - 5.7e-08 32.7 4.6 1.1e-06 28.4 1.4 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR69994.1 - 2e-05 25.1 0.3 0.009 16.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR69994.1 - 0.00039 19.7 0.0 0.0015 17.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR69994.1 - 0.0055 16.0 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 EMR69994.1 - 0.018 13.8 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 EMR69994.1 - 0.032 13.1 0.1 0.06 12.2 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase DUF1467 PF07330.12 EMR69994.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) Rsbr_N PF08678.10 EMR69994.1 - 0.24 11.5 0.0 0.5 10.4 0.0 1.4 1 0 0 1 1 1 0 Rsbr N terminal ApbA PF02558.16 EMR69994.1 - 0.34 10.5 2.3 1.6 8.3 0.6 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_4 PF01565.23 EMR69995.1 - 2.6e-27 95.3 0.3 4.7e-27 94.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR69995.1 - 0.00027 21.0 0.7 0.00063 19.8 0.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like Transport_MerF PF11431.8 EMR69995.1 - 1.5 8.8 6.3 4.6 7.2 0.9 2.6 2 0 0 2 2 2 0 Membrane transport protein MerF Pyr_redox_3 PF13738.6 EMR69996.1 - 5.8e-13 48.8 0.0 1.6e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR69996.1 - 9.5e-12 45.0 0.1 2.9e-09 37.0 0.1 3.0 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EMR69996.1 - 1.5e-10 40.2 0.0 1.3e-09 37.0 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMR69996.1 - 6.1e-10 38.8 0.0 1.1e-08 34.7 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR69996.1 - 1.3e-08 34.4 0.0 6.8e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 EMR69996.1 - 1.1e-06 28.5 1.2 0.00035 20.3 0.1 3.5 2 2 2 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EMR69996.1 - 4.9e-06 25.9 0.0 0.0027 16.9 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EMR69996.1 - 0.00011 21.4 0.1 0.015 14.3 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 EMR69996.1 - 0.00016 22.2 0.0 0.091 13.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR69996.1 - 0.00081 18.6 0.0 0.015 14.4 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 EMR69996.1 - 0.0021 18.1 0.1 1.1 9.3 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EMR69996.1 - 0.0037 16.2 0.1 1.6 7.5 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase Shikimate_DH PF01488.20 EMR69996.1 - 0.0041 17.2 0.0 0.63 10.1 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Mqo PF06039.15 EMR69996.1 - 0.0056 15.3 0.0 1.5 7.3 0.0 2.6 3 0 0 3 3 3 2 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.24 EMR69996.1 - 0.007 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase PepX_C PF08530.10 EMR69996.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain HI0933_like PF03486.14 EMR69996.1 - 0.079 11.7 0.1 1.3 7.6 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 EMR69996.1 - 0.11 11.5 0.1 2 7.4 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyoxalase PF00903.25 EMR69997.1 - 2.9e-40 137.4 0.1 6e-19 68.5 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMR69997.1 - 9.2e-15 54.9 0.0 1.4e-05 25.3 0.0 4.2 2 2 2 4 4 4 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EMR69997.1 - 1.4e-06 28.5 0.0 0.047 13.8 0.0 3.2 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EMR69997.1 - 4.8e-05 24.1 0.0 0.38 11.6 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EMR69997.1 - 0.002 18.0 0.3 1.6 8.7 0.0 3.8 4 1 0 4 4 4 1 Glyoxalase-like domain MoaF PF10703.9 EMR69997.1 - 0.085 12.8 0.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 MoaF N-terminal domain CppA_N PF14506.6 EMR69997.1 - 0.093 12.8 0.1 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal 2OG-FeII_Oxy PF03171.20 EMR69998.1 - 5.3e-16 58.9 0.1 9.5e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMR69998.1 - 2.6e-09 37.9 0.0 4.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PTPA PF03095.15 EMR69999.1 - 1.3e-91 307.2 0.0 1.5e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein tRNA-synt_1b PF00579.25 EMR70000.1 - 1e-21 77.6 0.0 3.3e-21 75.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Sp38 PF07354.12 EMR70000.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Ribosomal_L13e PF01294.18 EMR70001.1 - 4e-70 235.3 0.9 5.4e-70 234.9 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Meth_synt_2 PF01717.18 EMR70003.1 - 6.3e-10 38.8 0.0 1.1e-06 28.2 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EMR70003.1 - 0.0059 16.2 0.0 0.03 13.8 0.0 2.1 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Thiolase_N PF00108.23 EMR70004.1 - 1.9e-70 237.2 1.3 2.5e-70 236.8 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMR70004.1 - 1.2e-40 137.9 0.6 2.8e-40 136.8 0.6 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMR70004.1 - 0.0012 18.5 0.9 0.0012 18.5 0.9 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DNA_methylase PF00145.17 EMR70006.1 - 2.5e-40 138.9 0.0 1.1e-28 100.6 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase DNA_binding_1 PF01035.20 EMR70006.1 - 0.0071 16.4 0.1 0.038 14.1 0.0 2.1 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain LRR_4 PF12799.7 EMR70007.1 - 1.4e-24 85.7 15.7 1.4e-05 25.3 0.1 7.3 7 1 1 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMR70007.1 - 5.8e-23 80.4 21.9 9.8e-08 31.6 1.4 7.1 2 2 6 8 8 8 7 Leucine rich repeat LRR_1 PF00560.33 EMR70007.1 - 3e-10 39.2 16.2 3.5 8.5 0.1 10.1 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 EMR70007.1 - 3.4e-06 26.7 24.6 0.19 11.9 0.6 9.4 10 0 0 10 10 10 2 Leucine Rich repeat Pribosyltran PF00156.27 EMR70009.1 - 1.9e-08 34.0 0.0 2.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fungal_trans PF04082.18 EMR70010.1 - 9.4e-13 47.8 0.1 1.6e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BILBO1_N PF18281.1 EMR70010.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 BILBO1 N-terminal domain Asp PF00026.23 EMR70011.1 - 3.7e-43 148.1 0.3 5e-35 121.4 0.3 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR70011.1 - 6.1e-11 42.9 0.2 1.2e-05 25.7 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMR70011.1 - 0.034 14.8 0.0 2.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease adh_short PF00106.25 EMR70012.1 - 3.8e-24 85.2 0.0 5e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70012.1 - 8.6e-18 64.7 0.0 5.6e-17 62.1 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70012.1 - 3.3e-08 33.6 0.0 4.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMR70012.1 - 0.0029 17.5 0.7 0.0044 16.9 0.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EMR70012.1 - 0.071 12.6 0.1 2.6 7.5 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 EMR70013.1 - 1e-57 196.0 0.0 1.4e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CHY PF05495.12 EMR70014.1 - 3.2e-10 40.4 11.0 3.2e-10 40.4 11.0 3.2 2 1 0 2 2 2 1 CHY zinc finger RWD PF05773.22 EMR70014.1 - 0.022 15.0 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 RWD domain Mu-like_Com PF10122.9 EMR70014.1 - 0.093 12.2 0.1 0.093 12.2 0.1 2.7 3 0 0 3 3 3 0 Mu-like prophage protein Com DUF677 PF05055.12 EMR70015.1 - 0.0025 16.8 0.0 0.0031 16.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF677) ING PF12998.7 EMR70015.1 - 0.012 16.2 2.5 0.27 11.8 1.3 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding IMD PF08397.11 EMR70015.1 - 0.19 11.1 3.9 0.29 10.5 3.9 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain 5TM-5TMR_LYT PF07694.12 EMR70015.1 - 9.6 5.7 11.5 13 5.3 11.5 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Oxidored-like PF09791.9 EMR70016.1 - 2.3e-24 84.8 1.9 2.3e-24 84.8 1.9 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DPM3 PF08285.11 EMR70017.1 - 5.3e-37 125.9 0.2 5.9e-37 125.8 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3007 PF11460.8 EMR70017.1 - 0.05 13.9 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Na_Ca_ex PF01699.24 EMR70018.1 - 1.9e-38 131.8 34.5 1.9e-23 83.1 16.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SLATT_5 PF18160.1 EMR70018.1 - 4.7 6.5 4.5 1.7 7.9 0.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3295 PF11702.8 EMR70020.1 - 5.4e-163 543.9 28.9 6.3e-163 543.7 28.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) Filament PF00038.21 EMR70021.1 - 0.00013 21.7 31.6 0.00013 21.7 31.6 7.4 1 1 6 7 7 7 5 Intermediate filament protein Fib_alpha PF08702.10 EMR70021.1 - 0.0086 16.3 1.9 0.0086 16.3 1.9 9.7 2 2 5 9 9 9 2 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 EMR70021.1 - 0.072 12.9 35.4 0.1 12.5 0.0 8.5 8 1 1 9 9 9 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Cep57_CLD_2 PF14197.6 EMR70022.1 - 0.32 11.1 7.2 0.088 12.9 2.6 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 YabA PF06156.13 EMR70022.1 - 1.7 9.4 4.3 14 6.4 0.3 2.5 2 0 0 2 2 2 0 Initiation control protein YabA His_Phos_1 PF00300.22 EMR70023.1 - 3e-17 63.0 0.0 8.6e-17 61.5 0.0 1.7 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF4376 PF14301.6 EMR70023.1 - 0.03 14.7 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) Kelch_4 PF13418.6 EMR70024.1 - 1.2e-23 82.8 5.5 3.7e-10 39.6 0.1 5.2 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EMR70024.1 - 6.5e-20 70.5 0.8 9.6e-09 34.7 0.2 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EMR70024.1 - 1.2e-19 70.0 13.8 1.5e-06 28.3 0.1 5.3 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EMR70024.1 - 1.6e-19 69.5 1.9 3.8e-06 26.8 0.0 5.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EMR70024.1 - 1.9e-18 66.0 5.1 2.1e-06 27.8 0.0 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EMR70024.1 - 2.9e-12 46.1 8.2 2.7e-06 27.1 0.0 5.3 5 1 1 6 6 6 2 Kelch motif CDRN PF05174.12 EMR70026.1 - 0.049 13.3 0.7 8.4 6.2 0.1 2.6 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus Hydrolase PF00702.26 EMR70027.1 - 3.2e-06 27.6 0.0 3e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR70027.1 - 2.1e-05 24.7 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HTH_CodY PF08222.11 EMR70027.1 - 0.11 12.1 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 CodY helix-turn-helix domain Cullin_binding PF03556.15 EMR70028.1 - 1.4e-33 115.8 1.9 2.1e-33 115.3 1.9 1.2 1 0 0 1 1 1 1 Cullin binding SET PF00856.28 EMR70029.1 - 4.8e-19 69.4 0.0 1.8e-17 64.3 0.0 2.6 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 EMR70029.1 - 3.7e-14 53.3 5.5 7.3e-14 52.3 5.5 1.5 1 0 0 1 1 1 1 Pre-SET motif PALP PF00291.25 EMR70029.1 - 0.065 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DNA_pol_phi PF04931.13 EMR70029.1 - 4 5.4 5.2 5.5 5.0 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EMR70029.1 - 6.5 5.8 10.8 12 4.9 10.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SbcCD_C PF13558.6 EMR70030.1 - 3.6e-07 30.3 0.0 1.1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EMR70030.1 - 0.001 18.6 0.2 0.0015 18.0 0.2 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Jnk-SapK_ap_N PF09744.9 EMR70030.1 - 0.22 11.7 7.0 0.077 13.2 4.2 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 EMR70030.1 - 1.9 6.9 6.8 2.7 6.4 6.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MFS_1 PF07690.16 EMR70031.1 - 1.7e-14 53.5 35.3 2.2e-14 53.2 35.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR70031.1 - 4e-14 52.6 4.3 1.8e-13 50.5 4.3 2.1 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 OppC_N PF12911.7 EMR70031.1 - 0.0027 17.7 0.8 0.0027 17.7 0.8 3.1 5 0 0 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C UBD PF16455.5 EMR70032.1 - 1.7e-36 124.6 1.9 1.1e-17 64.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-binding domain ubiquitin PF00240.23 EMR70032.1 - 0.00017 21.3 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EMR70032.1 - 0.0094 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SelP_N PF04592.14 EMR70032.1 - 1.5 8.2 17.9 3.4 7.0 17.9 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIF_alpha PF05793.12 EMR70032.1 - 1.7 7.2 12.5 0.89 8.1 2.1 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 EMR70032.1 - 9.6 6.7 24.8 0.08 13.3 4.6 3.0 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TauD PF02668.16 EMR70033.1 - 1e-49 169.8 0.2 1.2e-49 169.5 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAGK_cat PF00781.24 EMR70036.1 - 7e-25 87.1 0.0 1.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.12 EMR70037.1 - 8.4e-54 182.6 0.0 1e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Upf2 PF04050.14 EMR70037.1 - 0.13 13.0 0.1 0.2 12.4 0.1 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DPBB_1 PF03330.18 EMR70039.1 - 1.4e-06 28.4 0.7 2.5e-05 24.5 0.7 2.3 1 1 0 1 1 1 1 Lytic transglycolase AAA_11 PF13086.6 EMR70040.1 - 1.4e-09 38.1 0.1 1.5e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 AAA domain Metallophos PF00149.28 EMR70041.1 - 2.6e-12 47.7 0.4 3.1e-12 47.4 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2181 PF10223.9 EMR70041.1 - 0.038 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) TraD PF06412.11 EMR70042.1 - 0.064 13.1 0.1 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Conjugal transfer protein TraD Ank_4 PF13637.6 EMR70043.1 - 1.7e-17 63.5 1.3 1.6e-05 25.3 0.0 4.9 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EMR70043.1 - 1.5e-16 60.0 1.0 0.13 12.7 0.0 7.2 6 2 1 7 7 7 5 Ankyrin repeat Ank_2 PF12796.7 EMR70043.1 - 3.6e-15 56.3 0.0 3e-05 24.5 0.0 4.6 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR70043.1 - 1.1e-10 41.5 3.2 0.0055 17.0 0.1 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR70043.1 - 8.4e-10 38.1 6.8 0.0039 17.6 0.0 7.2 7 1 0 7 7 7 3 Ankyrin repeat HAUS6_N PF14661.6 EMR70044.1 - 2.1e-37 128.9 0.6 2.1e-37 128.9 0.6 2.2 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus GTP_EFTU PF00009.27 EMR70045.1 - 0.095 12.2 0.2 0.96 9.0 0.2 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 EMR70047.1 - 1.1e-32 113.3 60.0 1.4e-31 109.8 50.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR70047.1 - 0.016 14.1 28.5 0.059 12.2 9.6 2.2 2 0 0 2 2 2 0 MFS_1 like family Sugar_tr PF00083.24 EMR70048.1 - 5.8e-97 325.4 31.5 6.8e-97 325.2 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR70048.1 - 9.5e-21 74.1 27.4 9.5e-21 74.1 27.4 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF983 PF06170.12 EMR70048.1 - 6.7 7.2 9.8 0.74 10.3 0.8 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF983) Pkinase_Tyr PF07714.17 EMR70049.1 - 1.9e-08 34.0 0.0 0.00037 19.9 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 EMR70049.1 - 2e-08 33.9 0.1 0.00066 19.1 0.0 3.5 3 1 1 4 4 4 2 Protein kinase domain Forkhead PF00250.18 EMR70050.1 - 4.2e-33 113.5 0.4 7.1e-33 112.7 0.4 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EMR70050.1 - 1.2e-06 28.7 0.0 9.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 FHA domain Linker_histone PF00538.19 EMR70050.1 - 0.012 16.0 0.1 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 linker histone H1 and H5 family His_biosynth PF00977.21 EMR70051.1 - 2.2e-33 115.6 0.0 2.7e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF2985 PF11204.8 EMR70052.1 - 2.6e-36 123.6 0.6 4.9e-36 122.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) ADH_zinc_N PF00107.26 EMR70053.1 - 1.7e-16 60.4 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR70053.1 - 8.5e-13 48.1 0.0 2.2e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EMR70053.1 - 3.8e-06 26.6 0.0 5.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EMR70053.1 - 0.0059 15.9 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EMR70053.1 - 0.081 14.0 0.0 0.13 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HMG_box PF00505.19 EMR70054.1 - 2.2e-15 56.8 1.8 3.6e-15 56.1 1.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR70054.1 - 4.8e-06 27.1 0.6 1.1e-05 26.0 0.6 1.6 1 0 0 1 1 1 1 HMG-box domain ChpA-C PF03777.13 EMR70054.1 - 1.9 8.4 5.8 15 5.5 0.3 3.1 2 1 1 3 3 3 0 ChpA-C Acetyltransf_3 PF13302.7 EMR70055.1 - 8.8e-12 45.9 0.0 1.2e-11 45.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR70055.1 - 2.5e-10 40.6 0.1 3.5e-10 40.1 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMR70055.1 - 1.5e-07 31.7 0.0 2.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR70055.1 - 1e-06 29.1 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR70055.1 - 0.00026 20.9 0.0 0.00043 20.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR70055.1 - 0.0028 17.6 0.0 0.0075 16.2 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein CLU PF13236.6 EMR70056.1 - 5.6e-75 252.0 0.0 9.2e-75 251.3 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EMR70056.1 - 6.1e-50 169.7 0.0 1.8e-49 168.1 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EMR70056.1 - 4.3e-26 91.0 15.5 5.7e-12 45.7 1.7 4.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EMR70056.1 - 9.7e-25 85.7 4.4 8.5e-06 25.5 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.6 EMR70056.1 - 6e-24 84.2 0.0 1.9e-23 82.6 0.0 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 EMR70056.1 - 2.5e-06 27.5 0.0 2.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 EMR70056.1 - 0.00049 20.1 7.1 0.018 15.2 0.3 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR70056.1 - 0.00079 19.4 8.2 0.39 10.9 0.3 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EMR70056.1 - 0.0023 18.0 0.5 0.12 12.6 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR70056.1 - 0.0039 17.0 0.8 4.8 7.2 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMR70056.1 - 0.021 14.8 4.4 14 6.0 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR70056.1 - 1.7 8.9 4.2 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DDHD PF02862.17 EMR70056.1 - 2 8.5 5.9 3.3 7.8 3.0 2.2 2 0 0 2 2 2 0 DDHD domain TPR_4 PF07721.14 EMR70056.1 - 3.9 8.4 11.8 2.2 9.2 0.8 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF1682 PF07946.14 EMR70057.1 - 1.3e-112 376.2 3.7 1.5e-112 376.0 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Cid2 PF09774.9 EMR70057.1 - 0.021 15.3 2.6 0.034 14.6 2.6 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 p450 PF00067.22 EMR70057.1 - 3.6 6.2 6.9 6.6 5.3 6.9 1.5 1 1 0 1 1 1 0 Cytochrome P450 Haspin_kinase PF12330.8 EMR70058.1 - 1.5e-34 119.6 0.0 2e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain DUF4863 PF16155.5 EMR70058.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4863) Tubulin_3 PF14881.6 EMR70059.1 - 1.2e-79 266.2 0.0 1.7e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EMR70059.1 - 3.9e-43 146.5 0.0 7.5e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EMR70059.1 - 2.2e-05 24.7 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Ferric_reduct PF01794.19 EMR70060.1 - 1.1e-20 74.0 11.1 2.8e-20 72.7 11.1 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMR70060.1 - 1.1e-20 74.4 0.0 8.4e-12 45.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR70060.1 - 1.6e-14 53.9 0.0 8.3e-13 48.4 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain Thiamine_BP PF01910.17 EMR70062.1 - 5.6e-31 106.3 1.2 1.3e-30 105.2 1.2 1.6 1 0 0 1 1 1 1 Thiamine-binding protein Catalase PF00199.19 EMR70063.1 - 2e-162 540.7 0.0 2.5e-162 540.4 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 EMR70063.1 - 1e-44 151.9 0.7 1.7e-44 151.1 0.7 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 EMR70063.1 - 7.6e-19 67.7 0.0 1.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Fungal_trans PF04082.18 EMR70064.1 - 2.7e-05 23.4 0.2 4.5e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tnp_P_element PF12017.8 EMR70065.1 - 0.14 11.5 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Transposase protein Mnd1 PF03962.15 EMR70066.1 - 0.0058 16.9 4.1 2.8 8.3 0.0 4.5 5 0 0 5 5 5 1 Mnd1 HTH domain DUF3090 PF11290.8 EMR70066.1 - 0.056 13.3 0.8 11 5.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3090) Glycos_transf_2 PF00535.26 EMR70066.1 - 0.08 12.7 1.3 12 5.6 0.0 3.4 4 0 0 4 4 4 0 Glycosyl transferase family 2 ATP12 PF07542.11 EMR70066.1 - 4.5 7.4 7.4 4.6 7.3 0.4 3.1 1 1 1 3 3 3 0 ATP12 chaperone protein p450 PF00067.22 EMR70067.1 - 1.4e-54 185.6 0.0 3.1e-43 148.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 GPI-anchored PF10342.9 EMR70068.1 - 5.1e-05 23.9 0.1 0.00032 21.4 0.1 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family STE PF02200.16 EMR70069.1 - 2.6e-56 188.8 0.1 4.4e-56 188.0 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EMR70069.1 - 0.00092 19.5 4.2 0.0024 18.3 4.2 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR70069.1 - 0.047 14.5 2.5 0.11 13.4 2.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger HMG_box PF00505.19 EMR70070.1 - 3.9e-19 68.8 0.4 7.8e-19 67.9 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR70070.1 - 1.8e-05 25.3 0.1 3.6e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain EamA PF00892.20 EMR70071.1 - 1.2e-10 41.6 20.9 3.8e-05 23.9 2.0 2.5 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EMR70071.1 - 1.4e-08 34.3 0.0 2.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 EMR70071.1 - 7.3e-05 22.2 0.4 7.3e-05 22.2 0.4 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family PDR_assoc PF08370.11 EMR70071.1 - 0.0096 15.6 3.0 2.7 7.8 0.1 3.4 3 0 0 3 3 3 2 Plant PDR ABC transporter associated TrbC PF04956.13 EMR70071.1 - 0.4 10.9 7.6 1.3 9.3 3.1 3.5 3 0 0 3 3 3 0 TrbC/VIRB2 family CPP1-like PF11833.8 EMR70071.1 - 8.5 6.0 6.2 1.1 8.9 1.3 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AhpC-TSA_2 PF13911.6 EMR70072.1 - 2.1e-07 31.1 0.0 4.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EMR70072.1 - 8.9e-06 25.6 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMR70072.1 - 0.0006 19.6 0.0 0.033 13.9 0.0 2.1 1 1 0 1 1 1 1 Redoxin GMC_oxred_N PF00732.19 EMR70073.1 - 8.4e-61 205.9 0.0 1.3e-60 205.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR70073.1 - 6.2e-32 111.1 0.0 1.2e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Ifi-6-16 PF06140.13 EMR70073.1 - 3.3e-06 26.9 24.9 3.3e-06 26.9 24.9 2.4 2 0 0 2 2 2 1 Interferon-induced 6-16 family Lycopene_cycl PF05834.12 EMR70073.1 - 4.7e-05 22.6 0.2 7.5e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EMR70073.1 - 9e-05 22.2 0.6 0.18 11.3 0.0 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EMR70073.1 - 0.0033 16.7 0.1 0.0089 15.3 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EMR70073.1 - 0.0067 16.6 0.0 0.025 14.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CDC37_N PF03234.14 EMR70074.1 - 2.1e-44 151.5 1.6 2.1e-44 151.5 1.6 3.2 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EMR70074.1 - 2.5e-42 143.5 3.1 4.6e-42 142.7 1.4 2.2 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EMR70074.1 - 4.6e-32 110.1 2.4 4.6e-32 110.1 2.4 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain SesA PF17107.5 EMR70074.1 - 0.066 13.4 0.3 0.29 11.3 0.3 2.1 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_22 PF18833.1 EMR70074.1 - 0.088 13.0 0.6 0.28 11.3 0.6 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat EzrA PF06160.12 EMR70074.1 - 0.17 10.0 7.0 0.046 11.9 3.2 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA kleA_kleC PF17383.2 EMR70074.1 - 3.9 7.9 6.3 3.1 8.2 0.2 3.3 3 1 1 4 4 4 0 Uncharacterized KorC regulated protein A YebO PF13974.6 EMR70074.1 - 6.1 7.0 5.9 2.8 8.1 1.4 2.8 3 1 0 3 3 3 0 YebO-like protein SMC_N PF02463.19 EMR70075.1 - 4.3e-56 189.8 33.9 1.2e-55 188.3 33.9 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMR70075.1 - 1.6e-27 96.1 0.0 5.8e-27 94.3 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EMR70075.1 - 9.2e-15 55.2 11.1 1e-08 35.4 0.1 3.7 5 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMR70075.1 - 4.6e-10 39.8 61.3 1.1e-08 35.3 20.7 4.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EMR70075.1 - 1.7e-06 28.7 42.0 1.7e-06 28.7 42.0 7.3 2 2 2 4 4 4 1 AAA domain SbcCD_C PF13558.6 EMR70075.1 - 0.00042 20.5 0.0 0.0016 18.7 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EMR70075.1 - 0.0045 16.7 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CCP_MauG PF03150.14 EMR70075.1 - 7.8 7.1 7.0 34 5.0 0.0 4.2 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase GPI-anchored PF10342.9 EMR70076.1 - 0.00038 21.2 0.5 0.0024 18.6 0.1 2.1 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1899 PF08953.11 EMR70077.1 - 1.2e-22 79.6 1.7 6.2e-21 74.1 1.7 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EMR70077.1 - 7.4e-19 67.4 0.1 1.6e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EMR70077.1 - 8.8e-16 58.0 8.9 0.00029 21.6 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR70077.1 - 1.5e-08 34.8 0.1 0.027 14.8 0.1 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 EMR70077.1 - 0.025 14.8 0.8 0.025 14.8 0.8 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Ge1_WD40 PF16529.5 EMR70077.1 - 0.039 12.9 0.0 3.6 6.5 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EMR70077.1 - 0.056 12.1 0.1 0.53 8.9 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF3535 PF12054.8 EMR70078.1 - 5.1e-127 424.7 0.6 1.7e-125 419.7 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EMR70078.1 - 1.3e-65 221.4 0.0 5.8e-65 219.3 0.0 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR70078.1 - 1.3e-19 70.6 0.0 5e-19 68.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EMR70078.1 - 6.8e-18 63.2 2.0 0.034 14.4 0.0 8.2 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 EMR70078.1 - 1.7e-07 31.5 6.0 0.0004 20.7 0.1 6.1 7 0 0 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EMR70078.1 - 2e-06 28.3 0.3 0.25 12.0 0.0 4.2 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EMR70078.1 - 0.00015 22.1 8.0 19 5.9 0.0 7.7 9 0 0 9 9 9 2 HEAT-like repeat ERCC3_RAD25_C PF16203.5 EMR70078.1 - 0.031 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CLASP_N PF12348.8 EMR70078.1 - 0.089 12.3 0.4 9.7 5.7 0.0 3.2 3 1 0 3 3 3 0 CLASP N terminal Yippee-Mis18 PF03226.14 EMR70079.1 - 1e-15 57.8 0.5 1.1e-15 57.7 0.5 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EMR70079.1 - 0.014 15.6 2.3 0.19 12.0 2.3 2.1 1 1 0 1 1 1 0 C-terminal domain of RIG-I DUF2039 PF10217.9 EMR70079.1 - 0.017 15.5 1.1 0.1 13.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Zn_ribbon_SprT PF17283.2 EMR70079.1 - 0.033 14.1 0.5 6.3 6.8 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Evr1_Alr PF04777.13 EMR70079.1 - 0.12 12.9 0.9 1.8 9.1 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DEAD PF00270.29 EMR70080.1 - 1.2e-38 132.6 0.9 2.4e-38 131.7 0.9 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR70080.1 - 3.7e-29 101.3 0.1 3.2e-28 98.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR70080.1 - 2e-05 24.6 0.8 0.00035 20.6 0.1 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SesA PF17107.5 EMR70080.1 - 0.00039 20.6 1.4 0.00069 19.8 0.3 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CMS1 PF14617.6 EMR70080.1 - 0.0011 18.4 0.2 0.003 16.9 0.2 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit POB3_N PF17292.2 EMR70081.1 - 1e-32 112.4 0.5 2.9e-30 104.5 0.1 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 EMR70081.1 - 5.1e-31 106.4 0.4 2.3e-30 104.3 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EMR70081.1 - 1.1e-23 83.5 0.0 4.8e-22 78.2 0.0 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like RE_Bsp6I PF09504.10 EMR70081.1 - 0.14 11.8 0.2 0.46 10.1 0.1 1.9 2 0 0 2 2 2 0 Bsp6I restriction endonuclease DUF2201_N PF13203.6 EMR70081.1 - 0.24 11.0 0.1 0.24 11.0 0.1 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF4604 PF15377.6 EMR70081.1 - 8 6.9 19.1 1.5 9.2 13.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Cwf_Cwc_15 PF04889.12 EMR70081.1 - 9.8 5.8 17.9 2.8 7.6 14.2 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GGACT PF06094.12 EMR70082.1 - 1.2e-09 38.8 0.0 2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Abhydrolase_6 PF12697.7 EMR70083.1 - 1.8e-09 38.5 5.1 3e-09 37.8 5.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EMR70083.1 - 0.0072 15.8 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EMR70083.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.7 EMR70083.1 - 0.026 13.5 0.0 0.11 11.4 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 EMR70083.1 - 0.037 12.5 0.0 0.24 9.9 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 EMR70083.1 - 0.049 13.3 0.2 1.1 8.9 0.1 2.7 2 1 1 3 3 3 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EMR70083.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 EMR70084.1 - 2.2e-09 38.2 1.6 2.9e-09 37.9 1.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EMR70084.1 - 5.5e-09 35.9 1.2 6.7e-08 32.3 1.2 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EMR70084.1 - 2.5e-07 30.6 1.2 4.7e-07 29.7 1.2 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EMR70084.1 - 3.2e-07 29.9 0.7 7.6e-07 28.6 0.9 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EMR70084.1 - 4e-06 26.9 0.0 7.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EMR70084.1 - 2.5e-05 23.8 0.3 0.00013 21.6 0.3 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 EMR70084.1 - 6.1e-05 21.8 2.8 0.00034 19.4 2.3 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EMR70084.1 - 0.00027 20.7 2.0 0.0015 18.3 2.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.11 EMR70084.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Anillin PF08174.11 EMR70085.1 - 9.6e-10 39.0 0.0 2.7e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 EMR70085.1 - 3.6e-09 37.1 0.0 1.3e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 EMR70085.1 - 0.039 14.4 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 EMR70085.1 - 0.098 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain E1-E2_ATPase PF00122.20 EMR70086.1 - 2.4e-36 125.0 2.0 2.4e-36 125.0 2.0 3.9 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EMR70086.1 - 2.4e-18 67.2 0.0 6.1e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMR70086.1 - 5.6e-10 38.8 0.2 1.4e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMR70086.1 - 0.0035 17.1 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMR70086.1 - 0.019 15.0 0.0 0.064 13.3 0.0 1.9 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Amidase PF01425.21 EMR70087.1 - 8.9e-87 291.9 0.0 1.6e-86 291.0 0.0 1.4 1 1 0 1 1 1 1 Amidase Methyltransf_25 PF13649.6 EMR70087.1 - 2.3e-13 50.7 0.0 5.7e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR70087.1 - 1.8e-12 47.3 0.0 3.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR70087.1 - 6e-10 39.6 0.4 1.7e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR70087.1 - 5.2e-08 33.5 0.0 9.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR70087.1 - 8.5e-05 22.2 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EMR70087.1 - 0.00019 21.3 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EMR70087.1 - 0.00085 19.2 0.3 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EMR70087.1 - 0.0011 18.4 0.1 0.0019 17.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EMR70087.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EMR70087.1 - 0.003 17.5 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EMR70087.1 - 0.033 13.3 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.7 EMR70087.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EMR70087.1 - 0.17 11.0 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase zf-CCCH PF00642.24 EMR70088.1 - 1.1e-20 73.0 29.7 6.9e-07 29.0 0.4 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EMR70088.1 - 2.2e-15 56.1 31.8 4.3e-06 26.6 2.5 5.5 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 EMR70088.1 - 2.2e-11 44.4 23.7 0.0027 18.4 0.5 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 EMR70088.1 - 1e-07 31.5 33.9 0.0026 17.5 0.4 5.7 5 1 0 5 5 5 5 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EMR70088.1 - 8.8 6.6 15.7 9.2 6.5 2.8 3.2 1 1 2 3 3 3 0 Zinc-finger containing family ubiquitin PF00240.23 EMR70089.1 - 4.8e-19 67.9 0.0 7.9e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EMR70089.1 - 3.7e-07 29.9 0.0 9.7e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EMR70089.1 - 0.00052 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EMR70089.1 - 0.00065 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMR70089.1 - 0.027 15.0 0.0 0.047 14.3 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 EMR70089.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_2 PF14560.6 EMR70089.1 - 0.15 12.5 0.2 1.2 9.6 0.2 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain STI1 PF17830.1 EMR70089.1 - 0.2 11.6 14.0 2.1 8.4 0.9 2.9 1 1 1 2 2 2 0 STI1 domain GerD PF17898.1 EMR70089.1 - 2.1 8.3 4.6 10 6.1 4.6 2.0 1 1 0 1 1 1 0 Spore germination GerD central core domain M20_dimer PF07687.14 EMR70090.1 - 1e-16 60.8 0.1 2.1e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EMR70090.1 - 5e-13 49.2 0.3 6.2e-13 48.9 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EMR70090.1 - 0.00037 20.2 0.0 0.00089 19.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Cu_amine_oxid PF01179.20 EMR70091.1 - 4.1e-121 404.7 0.5 5.1e-121 404.4 0.5 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EMR70091.1 - 2e-09 37.1 0.1 5.3e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Ank_2 PF12796.7 EMR70092.1 - 5.7e-117 382.5 1.1 4.4e-16 59.2 0.0 9.5 1 1 10 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR70092.1 - 2.1e-70 232.3 3.0 2.1e-09 37.7 0.0 12.9 3 3 12 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR70092.1 - 1.1e-69 222.1 1.7 0.00093 19.5 0.0 16.9 17 0 0 17 17 17 13 Ankyrin repeat Ank PF00023.30 EMR70092.1 - 1.5e-68 224.5 0.0 3e-05 24.3 0.0 16.2 17 0 0 17 17 17 13 Ankyrin repeat Ank_5 PF13857.6 EMR70092.1 - 2.2e-50 168.0 8.0 4e-07 30.2 0.0 11.9 5 3 6 12 12 12 11 Ankyrin repeats (many copies) NMT1 PF09084.11 EMR70092.1 - 0.061 13.3 0.0 3 7.7 0.0 2.5 1 1 0 2 2 2 0 NMT1/THI5 like VWA_3_C PF18571.1 EMR70092.1 - 0.1 12.5 13.6 2.6 8.0 0.1 5.9 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain Glyco_hydro_127 PF07944.12 EMR70093.1 - 2.5e-98 329.9 0.0 4.5e-98 329.0 0.0 1.4 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 EMR70093.1 - 0.0088 15.2 0.1 0.44 9.6 0.0 2.4 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 DUF402 PF04167.13 EMR70094.1 - 0.25 11.6 2.1 13 6.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF402) Peptidase_S8 PF00082.22 EMR70095.1 - 9.5e-14 51.3 0.3 1.4e-13 50.8 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_31 PF01055.26 EMR70096.1 - 3.5e-117 392.3 1.2 4.8e-117 391.8 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EMR70096.1 - 1.3e-13 51.1 0.1 2.4e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DUF1776 PF08643.10 EMR70097.1 - 1.1e-99 333.6 0.0 4.7e-99 331.5 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Pap_E4 PF02711.14 EMR70097.1 - 0.11 13.5 4.0 0.29 12.1 4.0 1.6 1 0 0 1 1 1 0 E4 protein Lactamase_B PF00753.27 EMR70099.1 - 1.9e-06 28.1 0.1 2.7e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ADH_zinc_N PF00107.26 EMR70100.1 - 2.1e-32 111.8 0.8 3.5e-32 111.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR70100.1 - 4.2e-13 50.5 0.0 6.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR70100.1 - 9e-06 25.5 0.0 2.2e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EMR70100.1 - 0.0018 17.6 1.3 0.0026 17.1 1.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EMR70100.1 - 0.012 15.9 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 EMR70100.1 - 0.026 14.0 0.4 0.037 13.5 0.4 1.3 1 0 0 1 1 1 0 short chain dehydrogenase HupF_HypC PF01455.18 EMR70100.1 - 0.054 13.6 0.2 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 HupF/HypC family DUF1254 PF06863.12 EMR70100.1 - 0.16 12.1 0.2 1.3 9.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1254) DUF2109 PF09882.9 EMR70101.1 - 0.034 14.2 7.6 0.036 14.1 0.3 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) Polysacc_synt_C PF14667.6 EMR70102.1 - 0.0028 17.7 8.6 0.0043 17.1 8.6 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain Strabismus PF06638.11 EMR70102.1 - 0.2 10.3 2.0 0.24 10.0 2.0 1.0 1 0 0 1 1 1 0 Strabismus protein Malate_synthase PF01274.22 EMR70103.1 - 0.037 12.3 0.1 0.053 11.8 0.1 1.1 1 0 0 1 1 1 0 Malate synthase 4PPT_N PF17837.1 EMR70103.1 - 0.1 12.7 0.0 14 5.9 0.0 2.7 3 0 0 3 3 3 0 4'-phosphopantetheinyl transferase N-terminal domain Tfb5 PF06331.12 EMR70103.1 - 0.13 12.3 0.3 0.13 12.3 0.3 1.9 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 Transferase PF02458.15 EMR70104.1 - 5.3e-07 28.6 0.0 1.4e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Transferase family DUF1729 PF08354.10 EMR70105.1 - 4.7e-141 469.8 0.0 6.6e-141 469.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EMR70105.1 - 1.7e-56 192.0 0.0 2.9e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain MaoC_dehydratas PF01575.19 EMR70105.1 - 1.2e-23 83.0 0.0 2.3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 EMR70105.1 - 5e-15 55.9 0.3 1e-14 54.9 0.3 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 EMR70105.1 - 4.5e-05 23.6 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_meander PF17951.1 EMR70105.1 - 0.00032 20.5 0.0 0.00094 19.0 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain Fas_alpha_ACP PF18325.1 EMR70106.1 - 1.8e-52 177.9 0.0 3.7e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 EMR70106.1 - 1.1e-39 136.2 0.2 1.9e-39 135.4 0.2 1.3 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 EMR70106.1 - 1.5e-22 80.4 0.1 3e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR70106.1 - 2.1e-16 60.0 0.1 6.3e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EMR70106.1 - 3.7e-09 36.3 0.0 2.7e-08 33.5 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70106.1 - 7.3e-05 22.4 0.0 0.00024 20.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70106.1 - 0.00024 21.1 0.0 0.0059 16.5 0.0 2.6 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.17 EMR70106.1 - 0.0044 17.6 0.0 0.018 15.6 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 EMR70106.1 - 0.011 15.2 0.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EMR70106.1 - 0.013 15.6 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 EMR70106.1 - 0.019 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMR70106.1 - 0.14 11.3 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Citrate_synt PF00285.21 EMR70107.1 - 1.9e-96 323.3 0.0 2.3e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Transposase_21 PF02992.14 EMR70107.1 - 0.19 11.0 0.0 0.86 8.8 0.0 1.9 2 0 0 2 2 2 0 Transposase family tnp2 ADH_zinc_N_2 PF13602.6 EMR70108.1 - 7.7e-11 43.2 0.0 7.3e-10 40.0 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR70108.1 - 2e-06 27.8 0.2 4.8e-06 26.6 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR70108.1 - 0.00079 19.3 0.0 0.0066 16.3 0.0 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 EMR70109.1 - 9.3e-76 254.7 0.0 1.4e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR70109.1 - 3e-35 120.8 0.1 6.4e-35 119.7 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR70109.1 - 5e-15 55.9 0.0 1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EMR70109.1 - 0.00037 19.9 0.2 0.00066 19.1 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glyco_hydro_43 PF04616.14 EMR70110.1 - 1.3e-32 113.3 0.3 1.8e-32 112.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LRR_10 PF18805.1 EMR70110.1 - 0.035 13.7 0.1 0.093 12.4 0.0 1.6 2 0 0 2 2 2 0 Leucine-rich repeat DLH PF01738.18 EMR70111.1 - 3.3e-23 82.4 0.0 3.8e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EMR70111.1 - 0.0015 18.3 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fig1 PF12351.8 EMR70112.1 - 7.4e-18 65.1 0.3 7.2e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EMR70112.1 - 0.009 15.7 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family LPAM_1 PF08139.12 EMR70112.1 - 0.25 11.9 3.0 0.51 10.9 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Glyoxalase PF00903.25 EMR70113.1 - 6e-12 45.9 0.0 1.5e-10 41.4 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMR70113.1 - 2.1e-09 37.6 0.0 4.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EMR70113.1 - 0.0013 18.9 0.0 0.0036 17.4 0.0 1.8 3 0 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EMR70113.1 - 0.019 14.9 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EMR70113.1 - 0.028 15.2 0.0 0.27 12.0 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase-like domain PIG-H PF10181.9 EMR70115.1 - 1.2e-24 85.9 0.2 7.5e-24 83.4 0.1 2.0 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component SSP160 PF06933.11 EMR70115.1 - 0.05 11.8 7.8 0.064 11.5 7.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RNA_pol_Rpb4 PF03874.16 EMR70116.1 - 6.6e-21 74.9 0.0 7.8e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 PseudoU_synth_1 PF01416.20 EMR70117.1 - 2e-34 118.3 0.0 3.9e-33 114.1 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase Striatin PF08232.12 EMR70117.1 - 0.21 12.2 7.3 0.33 11.5 0.2 2.3 2 0 0 2 2 2 0 Striatin family Ribosomal_S25 PF03297.15 EMR70117.1 - 5 7.4 10.5 0.26 11.5 2.7 2.4 2 0 0 2 2 2 0 S25 ribosomal protein CBFD_NFYB_HMF PF00808.23 EMR70118.1 - 1.8e-17 63.4 0.2 3.5e-17 62.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMR70118.1 - 3.8e-06 27.3 0.1 2.5e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Spidroin_MaSp PF11260.8 EMR70118.1 - 0.021 15.1 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Bromo_TP PF07524.13 EMR70118.1 - 0.098 12.7 0.1 0.23 11.5 0.0 1.6 1 1 1 2 2 2 0 Bromodomain associated TFIID-31kDa PF02291.15 EMR70118.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.5 1 1 1 2 2 2 0 Transcription initiation factor IID, 31kD subunit Aldedh PF00171.22 EMR70119.1 - 1.5e-134 449.0 0.0 1.8e-134 448.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMR70119.1 - 2.3e-05 23.6 0.0 4.6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RRM_1 PF00076.22 EMR70120.1 - 2.3e-07 30.5 0.0 2e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nbl1_Borealin_N PF10444.9 EMR70120.1 - 0.023 14.4 0.6 1.9 8.2 0.1 2.6 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal PBD PF00786.28 EMR70121.1 - 0.15 12.5 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 P21-Rho-binding domain DUF2670 PF10875.8 EMR70121.1 - 0.17 12.0 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) SMK-1 PF04802.15 EMR70123.1 - 2.7e-82 275.2 0.6 7.9e-82 273.7 0.6 1.8 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 LPD22 PF18834.1 EMR70123.1 - 0.0045 17.2 0.2 0.033 14.4 0.4 2.2 2 0 0 2 2 2 1 Large polyvalent protein associated domain 22 ADH_zinc_N PF00107.26 EMR70124.1 - 1.8e-16 60.3 0.2 2.7e-16 59.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR70124.1 - 6.4e-08 33.7 0.2 1.2e-07 32.9 0.2 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR70124.1 - 0.0053 16.2 0.2 0.01 15.3 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 EMR70124.1 - 0.0059 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EMR70126.1 - 2.4e-32 112.0 0.2 3.4e-32 111.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70126.1 - 1.2e-25 90.5 0.1 1.5e-25 90.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EMR70126.1 - 4.2e-07 30.0 0.1 6.9e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMR70126.1 - 3.6e-06 27.0 0.1 6.4e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EMR70126.1 - 5.9e-05 22.7 0.1 9e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR70126.1 - 0.00087 18.8 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Flagellin_D3 PF08884.11 EMR70126.1 - 0.017 15.5 1.2 4 7.9 0.1 2.4 2 0 0 2 2 2 0 Flagellin D3 domain ADH_zinc_N PF00107.26 EMR70126.1 - 0.041 13.8 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 EMR70126.1 - 0.043 13.2 0.0 0.075 12.4 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EMR70126.1 - 0.055 13.3 0.0 0.21 11.4 0.0 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EMR70126.1 - 0.059 12.5 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_16 PF00722.21 EMR70127.1 - 7.7e-08 32.0 1.1 1.3e-07 31.3 0.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 BBE PF08031.12 EMR70128.1 - 0.00063 19.8 0.1 0.0013 18.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like KR PF08659.10 EMR70130.1 - 2.4e-61 206.8 0.0 6e-61 205.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EMR70130.1 - 8.8e-39 132.2 0.0 2.1e-38 131.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EMR70130.1 - 1.3e-37 129.6 0.0 3.3e-36 125.1 0.0 2.2 1 1 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EMR70130.1 - 6.2e-26 91.5 0.0 1.2e-12 48.0 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EMR70130.1 - 4.5e-17 62.5 2.0 1.5e-10 41.1 0.0 3.0 1 1 1 2 2 2 2 Acyl transferase domain ADH_zinc_N_2 PF13602.6 EMR70130.1 - 2.5e-14 54.5 0.0 2.2e-12 48.2 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR70130.1 - 5.2e-12 45.9 0.0 1.4e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EMR70130.1 - 2.3e-07 31.1 0.1 6.7e-07 29.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EMR70130.1 - 6.5e-07 29.0 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_11 PF08241.12 EMR70130.1 - 6.5e-06 26.7 0.0 1.9e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR70130.1 - 3.5e-05 24.5 0.0 8.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR70130.1 - 6.5e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR70130.1 - 7.4e-05 23.4 0.0 0.00036 21.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR70130.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR70130.1 - 0.0067 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AlaDh_PNT_C PF01262.21 EMR70130.1 - 0.11 11.8 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain KdpC PF02669.15 EMR70131.1 - 0.084 12.7 0.0 0.099 12.5 0.0 1.1 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Condensation PF00668.20 EMR70132.1 - 8.3e-251 832.4 0.0 1.6e-83 281.0 0.0 4.3 4 0 0 4 4 4 4 Condensation domain AMP-binding PF00501.28 EMR70132.1 - 1.3e-222 738.9 0.0 1.8e-70 237.7 0.0 4.7 4 1 1 5 5 5 4 AMP-binding enzyme PP-binding PF00550.25 EMR70132.1 - 7.4e-53 176.8 2.6 1.6e-12 47.6 0.1 5.4 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EMR70132.1 - 1.7e-20 73.8 0.0 2.1e-08 35.0 0.0 4.7 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 EMR70132.1 - 7.4e-06 25.9 0.0 0.00012 21.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR70132.1 - 2.2e-05 25.1 0.0 0.00011 22.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR70132.1 - 0.00075 20.2 0.0 0.0026 18.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR70132.1 - 0.00075 20.1 0.0 0.0028 18.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR70132.1 - 0.012 15.4 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FSH1 PF03959.13 EMR70134.1 - 1.8e-19 70.3 0.0 2.1e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) GMC_oxred_N PF00732.19 EMR70135.1 - 1.5e-44 152.6 0.0 3.3e-44 151.4 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR70135.1 - 2.4e-33 115.7 0.0 4.2e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DUF4858 PF16150.5 EMR70138.1 - 0.024 14.7 0.3 0.1 12.6 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4858) zf-CCHC_4 PF14392.6 EMR70138.1 - 0.64 9.8 6.8 1.8 8.3 0.7 3.4 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.23 EMR70138.1 - 2 8.6 8.8 0.21 11.7 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF5102 PF17104.5 EMR70139.1 - 5.7e-24 85.7 19.5 1.5e-16 61.3 0.3 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF5102) RRM_1 PF00076.22 EMR70140.1 - 1.9e-09 37.2 1.4 0.00096 18.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTP_transferase PF00483.23 EMR70143.1 - 8.6e-42 143.4 0.0 9.4e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EMR70143.1 - 4e-11 43.5 0.0 4.7e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EMR70143.1 - 0.015 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 EMR70143.1 - 0.035 14.0 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase BRAP2 PF07576.12 EMR70144.1 - 1.4e-28 99.0 0.0 2.8e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EMR70144.1 - 3.2e-18 65.8 6.1 1.1e-17 64.1 6.4 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein NBD94 PF16830.5 EMR70144.1 - 0.061 13.7 0.1 4.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH YabA PF06156.13 EMR70144.1 - 1.1 9.9 6.6 0.57 10.8 1.2 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF3584 PF12128.8 EMR70144.1 - 1.7 6.1 13.8 2.3 5.6 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 EMR70144.1 - 5.5 6.5 8.2 8.2 5.9 8.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ubiquitin PF00240.23 EMR70145.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EMR70145.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMR70145.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EMR70145.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EMR70145.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMR70145.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMR70145.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EMR70145.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EMR70145.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EMR70145.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 EMR70145.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EMR70145.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 EMR70145.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 EMR70145.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 EMR70145.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EMR70145.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 EMR70145.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 EMR70145.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 EMR70145.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 EMR70145.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 EMR70145.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EMR70145.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 EMR70145.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 EMR70145.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 EMR70145.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 EMR70145.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 EMR70145.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 EMR70146.1 - 0.0035 17.4 7.2 0.0069 16.5 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carb_anhydrase PF00194.21 EMR70147.1 - 2.1e-29 102.9 0.0 1.2e-28 100.4 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase P_gingi_FimA PF06321.11 EMR70147.1 - 0.02 15.0 0.1 0.037 14.1 0.1 1.4 1 0 0 1 1 1 0 Major fimbrial subunit protein (FimA) MFS_1 PF07690.16 EMR70149.1 - 1.4e-32 113.1 55.6 4.8e-31 108.0 53.6 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.15 EMR70150.1 - 3.9e-20 72.0 36.8 3.3e-18 65.7 37.2 2.8 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin tRNA_edit PF04073.15 EMR70150.1 - 0.098 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain DUF3632 PF12311.8 EMR70151.1 - 1.9e-36 126.1 0.3 2.5e-36 125.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) SAD_SRA PF02182.17 EMR70153.1 - 6.1e-35 120.2 0.0 1.1e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain HgmA PF04209.13 EMR70154.1 - 1.1e-148 495.5 0.0 1.3e-148 495.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase ThiF PF00899.21 EMR70155.1 - 2.3e-40 138.5 0.0 4.1e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EMR70155.1 - 0.00044 20.5 3.5 0.75 10.1 0.2 3.3 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EMR70155.1 - 0.0075 16.7 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EMR70155.1 - 0.015 14.9 0.1 0.036 13.7 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.23 EMR70155.1 - 0.022 14.9 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.18 EMR70155.1 - 0.027 14.7 0.9 0.094 13.0 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 EMR70155.1 - 0.058 13.0 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NUDIX PF00293.28 EMR70156.1 - 4e-05 23.7 0.0 0.00012 22.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain DUF3430 PF11912.8 EMR70157.1 - 0.02 14.9 0.0 0.022 14.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) MiAMP1 PF09117.10 EMR70157.1 - 0.075 13.3 1.1 0.27 11.5 1.1 1.8 1 1 0 1 1 1 0 MiAMP1 SRA1 PF07304.11 EMR70158.1 - 1.8e-09 37.5 0.1 1.8e-09 37.5 0.1 2.4 1 1 1 2 2 2 1 Steroid receptor RNA activator (SRA1) EloA-BP1 PF15870.5 EMR70159.1 - 0.21 11.9 1.3 0.28 11.4 0.2 1.6 2 0 0 2 2 2 0 ElonginA binding-protein 1 FAD_binding_3 PF01494.19 EMR70160.1 - 3.6e-21 75.8 0.1 1.3e-20 74.0 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR70160.1 - 2.8e-05 23.5 0.3 0.0055 16.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR70160.1 - 4.6e-05 23.2 0.9 0.00031 20.4 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR70160.1 - 0.00011 21.2 0.0 0.16 10.8 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EMR70160.1 - 0.0016 18.6 1.2 0.0062 16.7 0.8 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMR70160.1 - 0.0037 17.8 0.4 0.091 13.3 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMR70160.1 - 0.0074 16.5 0.1 0.065 13.5 0.1 2.3 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 EMR70160.1 - 0.028 13.5 0.0 0.064 12.3 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein SE PF08491.10 EMR70160.1 - 0.085 11.9 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_2 PF00890.24 EMR70160.1 - 0.24 10.4 1.5 0.44 9.6 1.1 1.6 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 EMR70161.1 - 3.4e-58 197.6 0.0 1.4e-37 129.8 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 EMR70161.1 - 6.7e-42 143.3 0.0 1e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.17 EMR70161.1 - 0.0019 17.5 0.1 0.0086 15.3 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EMR70161.1 - 0.0019 17.4 0.1 0.0037 16.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EMR70161.1 - 0.005 15.8 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 EMR70161.1 - 0.014 14.9 0.1 0.11 12.0 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EMR70161.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR70161.1 - 0.041 13.1 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR70161.1 - 0.079 13.2 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR70162.1 - 1.6e-16 60.4 0.0 1.7e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR70162.1 - 2.6e-07 30.1 0.3 4.6e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMR70162.1 - 6.9e-05 22.2 0.1 0.018 14.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR70162.1 - 0.0001 22.3 1.7 0.046 13.7 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 EMR70162.1 - 0.00037 19.7 1.4 0.025 13.7 0.3 2.2 1 1 1 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EMR70162.1 - 0.00038 19.6 0.7 0.093 11.8 0.2 2.1 1 1 1 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 EMR70162.1 - 0.00069 19.3 4.9 0.24 10.9 0.3 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR70162.1 - 0.0023 18.1 0.3 0.0049 17.1 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMR70162.1 - 0.0039 15.9 0.5 0.03 13.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EMR70162.1 - 0.0067 15.6 0.1 0.087 11.9 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 EMR70162.1 - 0.039 13.2 0.1 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Metallophos PF00149.28 EMR70163.1 - 4.9e-05 23.9 0.0 6.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMR70163.1 - 0.09 13.0 0.0 4.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Prenyltrans PF00432.21 EMR70164.1 - 6e-57 189.1 6.3 1.4e-12 47.1 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EMR70164.1 - 0.00014 21.1 0.0 0.041 13.0 0.0 3.4 2 1 2 4 4 4 1 Squalene-hopene cyclase N-terminal domain MCM PF00493.23 EMR70165.1 - 3.3e-104 346.9 0.0 5.2e-104 346.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMR70165.1 - 2.3e-30 105.0 1.4 4.2e-30 104.2 1.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EMR70165.1 - 2.5e-19 69.5 2.3 6.9e-19 68.1 2.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMR70165.1 - 4.3e-19 69.0 1.4 1.3e-18 67.5 1.4 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMR70165.1 - 1.5e-07 31.0 0.0 1.5e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMR70165.1 - 4e-06 26.9 0.0 1.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EMR70165.1 - 0.013 15.3 0.7 0.045 13.6 0.7 1.9 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 EMR70165.1 - 0.018 14.9 0.0 0.06 13.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EMR70165.1 - 0.039 14.6 1.9 0.21 12.2 1.7 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal TraI PF07057.11 EMR70165.1 - 0.13 12.4 0.2 0.29 11.3 0.2 1.6 1 0 0 1 1 1 0 DNA helicase TraI AAA PF00004.29 EMR70166.1 - 7.2e-44 149.4 0.0 1.7e-43 148.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMR70166.1 - 1.5e-10 40.7 0.1 4.1e-09 36.1 0.0 3.0 2 1 1 3 3 3 1 AAA+ lid domain RuvB_N PF05496.12 EMR70166.1 - 0.0012 18.6 0.0 0.0049 16.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR70166.1 - 0.0055 17.0 0.1 0.67 10.2 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EMR70166.1 - 0.0067 16.8 6.7 0.12 12.7 0.1 3.3 2 2 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 EMR70166.1 - 0.03 14.5 0.2 0.087 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 EMR70166.1 - 0.041 13.9 0.0 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 EMR70166.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EMR70166.1 - 0.1 12.0 0.0 0.35 10.2 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EMR70166.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RRS1 PF04939.12 EMR70167.1 - 7.9e-43 146.1 0.0 1.1e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Pkinase PF00069.25 EMR70168.1 - 4.7e-55 186.8 0.0 6.5e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR70168.1 - 2.6e-39 135.0 0.0 3.9e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR70168.1 - 0.00038 19.9 0.0 0.011 15.1 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMR70168.1 - 0.003 16.4 0.0 0.0077 15.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EMR70168.1 - 0.063 13.2 0.1 0.29 11.0 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EMR70168.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMR70168.1 - 0.19 10.6 0.0 1.5 7.7 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain DAP3 PF10236.9 EMR70169.1 - 2.8e-93 312.5 0.0 3.5e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EMR70169.1 - 2.7e-06 27.9 0.0 8.4e-06 26.3 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMR70169.1 - 0.057 13.2 0.3 0.56 10.0 0.1 2.3 1 1 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 EMR70169.1 - 0.084 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EMR70169.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain HET PF06985.11 EMR70171.1 - 3e-11 43.8 0.1 9.7e-09 35.7 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Clr5 PF14420.6 EMR70174.1 - 6.9e-11 42.2 0.0 2.6e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Clr5 domain EOS1 PF12326.8 EMR70174.1 - 0.0066 16.4 0.2 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 N-glycosylation protein DUF775 PF05603.12 EMR70174.1 - 0.14 11.6 11.3 0.072 12.6 6.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DDHD PF02862.17 EMR70174.1 - 0.29 11.3 8.0 0.062 13.4 2.6 2.0 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.16 EMR70174.1 - 0.39 10.7 7.7 0.51 10.4 2.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1980 PF09323.10 EMR70174.1 - 0.45 10.4 2.2 0.88 9.5 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Pex14_N PF04695.13 EMR70174.1 - 0.64 10.7 19.3 5.8 7.5 14.9 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 EMR70174.1 - 0.75 9.4 33.1 0.41 10.2 27.5 2.1 2 0 0 2 2 2 0 Spt20 family Connexin PF00029.19 EMR70174.1 - 0.92 9.2 6.1 1.8 8.2 6.1 1.4 1 0 0 1 1 1 0 Connexin eIF3_subunit PF08597.10 EMR70174.1 - 1.1 9.2 14.3 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit BNIP2 PF12496.8 EMR70174.1 - 1.1 9.7 7.5 0.31 11.5 4.4 1.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 G0-G1_switch_2 PF15103.6 EMR70174.1 - 1.3 9.5 8.3 0.81 10.1 5.6 1.9 2 0 0 2 2 2 0 G0/G1 switch protein 2 eIF-3_zeta PF05091.12 EMR70174.1 - 1.6 7.6 17.7 2.6 6.9 17.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LMBR1 PF04791.16 EMR70174.1 - 2.4 7.0 4.2 3.7 6.4 4.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CCDC53 PF10152.9 EMR70174.1 - 3.2 8.2 13.7 19 5.7 9.5 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ctr PF04145.15 EMR70174.1 - 3.8 8.1 10.3 7.4 7.2 6.9 2.2 2 0 0 2 2 2 0 Ctr copper transporter family DUF5327 PF17261.2 EMR70174.1 - 4.2 8.2 17.3 15 6.4 12.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Baculo_PP31 PF05311.11 EMR70174.1 - 4.2 6.8 14.5 0.68 9.4 10.7 1.5 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF5353 PF17304.2 EMR70175.1 - 1.6e-13 50.2 4.0 3.5e-13 49.1 3.8 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5353) GFA PF04828.14 EMR70177.1 - 3.7e-07 30.4 5.6 3.5e-05 24.0 0.1 2.8 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF3636 PF12331.8 EMR70178.1 - 2.6e-39 134.4 0.0 7.4e-39 132.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Mitofilin PF09731.9 EMR70178.1 - 0.22 10.3 11.9 0.32 9.8 11.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF508 PF04370.12 EMR70178.1 - 1.2 8.9 5.0 3.8 7.2 5.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF508) CTP_transf_1 PF01148.20 EMR70179.1 - 5.3e-80 269.0 20.2 6.4e-80 268.7 20.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2304 PF10066.9 EMR70179.1 - 2.2 8.6 9.5 5.8 7.2 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Sulfate_transp PF00916.20 EMR70180.1 - 3.4e-76 256.5 8.7 5.4e-76 255.8 8.7 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMR70180.1 - 4.3e-16 58.6 0.0 8.4e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EMR70180.1 - 1.2e-07 32.0 0.0 1e-06 29.0 0.0 2.5 2 1 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 EMR70180.1 - 0.017 15.5 3.8 0.017 15.5 3.8 2.8 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF1286 PF06939.11 EMR70180.1 - 0.85 9.9 8.3 0.69 10.2 1.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1286) CHCH PF06747.13 EMR70181.1 - 4.7e-07 29.8 5.5 7.9e-07 29.1 5.5 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EMR70181.1 - 0.017 15.5 1.6 0.035 14.5 1.6 1.5 1 0 0 1 1 1 0 GCK domain DIOX_N PF14226.6 EMR70182.1 - 6.1e-22 78.6 0.1 1.1e-20 74.5 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR70182.1 - 5.6e-12 46.0 0.0 1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPK_catalytic PF04263.16 EMR70183.1 - 2.1e-22 79.4 0.0 1.4e-21 76.8 0.0 2.3 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EMR70183.1 - 1.9e-20 72.3 0.1 3.5e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Eapp_C PF10238.9 EMR70183.1 - 0.16 12.0 6.0 1.3 9.1 0.8 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein FAM176 PF14851.6 EMR70183.1 - 0.16 11.6 6.7 0.53 9.9 0.2 2.4 2 0 0 2 2 2 0 FAM176 family RNA_polI_A34 PF08208.11 EMR70183.1 - 0.37 10.9 14.2 0.059 13.5 1.6 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 NST1 PF13945.6 EMR70183.1 - 0.45 10.6 12.7 0.069 13.3 5.5 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator TFB6 PF17110.5 EMR70183.1 - 0.75 9.5 5.2 0.61 9.8 0.4 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RPN2_C PF18004.1 EMR70183.1 - 0.9 9.4 12.5 0.28 11.1 1.2 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF5568 PF17724.1 EMR70183.1 - 1.6 8.5 7.2 0.49 10.2 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5568) AP3D1 PF06375.11 EMR70183.1 - 2 8.6 16.7 2.2 8.5 7.1 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Coilin_N PF15862.5 EMR70183.1 - 2.8 7.7 14.9 0.12 12.2 2.7 2.3 2 0 0 2 2 2 0 Coilin N-terminus Vfa1 PF08432.10 EMR70183.1 - 2.9 8.2 13.5 8.1 6.7 1.3 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.13 EMR70183.1 - 5.4 5.7 9.6 6.8 5.4 1.5 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 UCH PF00443.29 EMR70184.1 - 1.1e-48 165.9 0.0 1.4e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMR70184.1 - 2.6e-12 47.0 5.1 3.9e-07 30.0 1.8 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EMR70184.1 - 5.7e-09 35.6 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF3510 PF12022.8 EMR70184.1 - 0.016 15.6 1.6 0.43 11.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) ARPC4 PF05856.12 EMR70185.1 - 1.6e-79 265.4 3.7 1.7e-79 265.2 3.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) F-box_4 PF15966.5 EMR70186.1 - 9.2e-05 22.3 0.6 0.00054 19.8 0.1 2.3 2 0 0 2 2 2 1 F-box F-box PF00646.33 EMR70186.1 - 0.00023 21.0 0.7 0.00023 21.0 0.7 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EMR70186.1 - 0.0028 17.5 0.1 0.0063 16.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like SnoaL PF07366.12 EMR70187.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EMR70187.1 - 0.00035 21.2 0.0 0.00094 19.8 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain DUF3915 PF13054.6 EMR70187.1 - 0.057 13.4 2.6 0.11 12.5 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Presenilin PF01080.17 EMR70187.1 - 0.29 9.8 2.6 0.42 9.3 2.6 1.1 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 EMR70187.1 - 0.63 8.3 12.0 0.91 7.7 12.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family Trypan_PARP PF05887.11 EMR70187.1 - 2.6 8.0 16.2 4.5 7.2 16.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2052 PF09747.9 EMR70188.1 - 1.7e-27 96.9 16.7 3e-26 92.8 16.7 2.0 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) GAT PF03127.14 EMR70190.1 - 1.9e-17 63.3 0.1 4.7e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 EMR70190.1 - 3.7e-06 26.9 0.0 7.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 VHS domain Nic96 PF04097.14 EMR70190.1 - 0.021 13.3 0.0 0.033 12.6 0.0 1.2 1 0 0 1 1 1 0 Nup93/Nic96 DUF983 PF06170.12 EMR70191.1 - 0.066 13.6 0.8 0.066 13.6 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF983) RE_AlwI PF09491.10 EMR70192.1 - 0.028 13.2 0.0 0.032 13.1 0.0 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF5562 PF17717.1 EMR70192.1 - 0.087 12.8 0.4 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5562) Hid1 PF12722.7 EMR70192.1 - 0.15 10.1 0.1 0.18 9.9 0.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4726 PF15855.5 EMR70192.1 - 0.19 12.0 2.2 15 5.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) MCPVI PF02993.14 EMR70193.1 - 0.11 12.3 0.6 0.22 11.4 0.6 1.4 1 0 0 1 1 1 0 Minor capsid protein VI SepF PF04472.12 EMR70194.1 - 0.091 13.0 0.3 0.2 11.9 0.1 1.7 2 0 0 2 2 2 0 Cell division protein SepF CAP_N PF01213.19 EMR70194.1 - 0.21 11.0 3.2 0.36 10.2 3.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NDT80_PhoG PF05224.12 EMR70195.1 - 1.4e-47 162.3 0.0 1.9e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pterin_bind PF00809.22 EMR70197.1 - 6.1e-78 261.9 0.0 7.9e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EMR70197.1 - 1.9e-36 124.9 0.0 3.3e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 EMR70198.1 - 1.7e-52 178.9 0.2 2.3e-52 178.5 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EMR70198.1 - 7.4e-14 51.5 0.3 1.2e-13 50.8 0.3 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EMR70198.1 - 1.6e-06 27.4 1.0 2.5e-06 26.7 1.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EMR70198.1 - 0.0015 17.8 0.1 0.0029 16.8 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EMR70198.1 - 0.0091 15.2 0.2 0.015 14.5 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase TGT PF01702.18 EMR70198.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase MIP PF00230.20 EMR70199.1 - 1.5e-43 149.2 14.3 1.8e-43 148.9 14.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein adh_short_C2 PF13561.6 EMR70200.1 - 2.6e-38 131.9 0.2 4.1e-38 131.2 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR70200.1 - 1.3e-31 109.6 0.0 2.5e-31 108.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR70200.1 - 1.3e-05 25.2 1.0 5.4e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 KR domain Glyco_tran_WecB PF03808.13 EMR70200.1 - 0.0053 16.7 0.2 0.14 12.1 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase WecB/TagA/CpsF family DUF1776 PF08643.10 EMR70200.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF676 PF05057.14 EMR70202.1 - 5.3e-43 147.1 0.3 4.2e-27 95.1 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) PGAP1 PF07819.13 EMR70202.1 - 0.014 15.1 0.1 0.041 13.6 0.1 1.7 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 EMR70202.1 - 0.036 13.4 0.0 0.082 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EMR70202.1 - 0.072 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) ArfGap PF01412.18 EMR70204.1 - 7.4e-35 119.6 1.1 1.4e-34 118.6 1.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Aminotran_1_2 PF00155.21 EMR70205.1 - 2.4e-65 221.1 0.0 2.7e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMR70205.1 - 0.00024 20.5 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMR70205.1 - 0.0015 17.2 0.1 0.0027 16.3 0.1 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMR70205.1 - 0.0016 17.8 0.1 0.0043 16.4 0.1 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EMR70205.1 - 0.041 12.9 0.0 0.079 11.9 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V Oxidored_q2 PF00420.24 EMR70206.1 - 0.036 13.7 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L WD40 PF00400.32 EMR70207.1 - 7.6e-11 42.4 2.8 0.0072 17.2 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.6 EMR70207.1 - 6.4e-05 23.3 0.2 0.22 12.1 0.0 4.8 4 1 1 5 5 5 1 PQQ-like domain PQQ_2 PF13360.6 EMR70207.1 - 0.0024 17.5 0.2 0.0087 15.7 0.2 2.0 1 1 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EMR70207.1 - 0.14 12.5 0.0 9.2 6.6 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-CSL PF05207.13 EMR70209.1 - 0.057 13.2 1.1 4.9 7.0 0.1 2.5 1 1 1 2 2 2 0 CSL zinc finger PS-DH PF14765.6 EMR70211.1 - 9.9e-45 153.0 0.0 1.5e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EMR70211.1 - 3.8e-38 131.2 0.2 1.2e-37 129.5 0.2 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EMR70211.1 - 2.1e-37 127.8 0.0 5.3e-37 126.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EMR70211.1 - 3.3e-35 122.1 0.0 7.5e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EMR70211.1 - 6.3e-23 81.7 0.1 3.3e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N PF00107.26 EMR70211.1 - 1.4e-14 54.2 0.5 7.7e-14 51.8 0.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EMR70211.1 - 1.4e-14 54.6 0.0 3.9e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR70211.1 - 3.2e-13 49.7 0.0 1.1e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EMR70211.1 - 3.3e-13 50.8 0.0 9.9e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EMR70211.1 - 5.5e-10 39.3 0.0 2e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR70211.1 - 1.3e-09 38.5 0.0 4e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR70211.1 - 1.5e-09 38.4 0.0 5.5e-09 36.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR70211.1 - 1.7e-09 37.9 0.0 4.8e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EMR70211.1 - 3.5e-07 29.9 0.0 9.7e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70211.1 - 5e-05 23.0 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 EMR70211.1 - 0.00049 19.9 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 EMR70211.1 - 0.0016 17.9 0.0 0.0058 16.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 EMR70211.1 - 0.0023 17.8 0.2 0.0051 16.7 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_28 PF02636.17 EMR70211.1 - 0.0037 16.9 0.0 0.028 14.0 0.0 2.4 3 0 0 3 3 3 1 Putative S-adenosyl-L-methionine-dependent methyltransferase SAT PF16073.5 EMR70211.1 - 0.012 15.4 0.3 0.058 13.1 0.3 2.1 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_33 PF10017.9 EMR70211.1 - 0.015 14.4 0.0 0.046 12.9 0.0 1.7 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Ribosomal_L20 PF00453.18 EMR70212.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L20 p450 PF00067.22 EMR70214.1 - 5.9e-43 147.3 0.0 5.1e-41 140.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 EMR70215.1 - 1.4e-34 119.6 24.9 1.4e-34 119.6 24.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR70215.1 - 8.5e-09 35.2 2.3 8.5e-09 35.2 2.3 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB 2TM PF13239.6 EMR70215.1 - 0.032 14.5 0.2 0.032 14.5 0.2 4.3 3 2 0 3 3 3 0 2TM domain TauD PF02668.16 EMR70217.1 - 5.6e-59 200.1 0.2 6.9e-59 199.8 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family COesterase PF00135.28 EMR70218.1 - 3.4e-83 280.3 0.0 4.5e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR70218.1 - 2.5e-07 30.8 0.1 4.6e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR70218.1 - 0.0018 17.8 0.1 0.0029 17.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EMR70218.1 - 0.034 14.8 0.1 0.1 13.2 0.0 1.8 1 1 0 2 2 2 0 Alpha/beta hydrolase family Glyco_hydro_64 PF16483.5 EMR70219.1 - 6.4e-120 400.8 0.0 7.5e-120 400.6 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF5524 PF17662.1 EMR70219.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5524) Alginate_lyase PF05426.12 EMR70220.1 - 0.0012 18.4 3.2 0.0019 17.8 3.2 1.4 1 1 0 1 1 1 1 Alginate lyase Glyco_hydro_61 PF03443.14 EMR70221.1 - 3.3e-66 223.1 0.0 3.9e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_7 PF13508.7 EMR70222.1 - 5.7e-08 33.1 0.0 7.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR70222.1 - 4.8e-07 30.0 0.0 7.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR70222.1 - 3.6e-06 26.9 0.0 5.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR70222.1 - 0.022 14.8 0.0 0.038 14.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR70222.1 - 0.2 11.7 0.0 0.46 10.5 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein HET PF06985.11 EMR70223.1 - 9.1e-36 123.4 0.0 1.5e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) S6PP_C PF08472.10 EMR70223.1 - 0.14 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Aminotran_1_2 PF00155.21 EMR70224.1 - 6.1e-25 88.2 0.0 1.7e-24 86.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMR70224.1 - 0.0016 17.1 0.0 0.0023 16.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydr_30_2 PF14587.6 EMR70225.1 - 1.7e-17 64.1 8.6 1.7e-17 64.1 8.6 1.7 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Melibiase_2 PF16499.5 EMR70226.1 - 4.2e-46 157.4 3.7 1.4e-45 155.7 3.7 1.7 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 EMR70226.1 - 0.029 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Melibiase Glyco_hydro_88 PF07470.13 EMR70227.1 - 7.3e-11 41.7 1.9 1.3e-10 40.9 1.9 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Trypan_PARP PF05887.11 EMR70228.1 - 3.3 7.7 11.6 5.4 7.0 11.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ADH_zinc_N PF00107.26 EMR70229.1 - 9.1e-14 51.6 0.0 2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR70229.1 - 0.00039 20.3 0.4 0.0013 18.6 0.4 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMR70229.1 - 0.0048 17.9 0.0 0.0082 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dabb PF07876.12 EMR70230.1 - 1.8e-06 28.5 0.0 2.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Abhydrolase_3 PF07859.13 EMR70231.1 - 5.5e-22 78.7 0.0 7.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMR70231.1 - 2.5e-06 26.6 0.0 8.8e-06 24.8 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EMR70231.1 - 0.00053 19.0 0.0 0.0083 15.0 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EMR70231.1 - 0.0088 16.7 5.0 0.0088 16.7 5.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EMR70231.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Cellulase PF00150.18 EMR70233.1 - 1.3e-19 70.8 0.9 1.8e-19 70.3 0.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EMR70233.1 - 3.3e-07 29.7 0.0 9.3e-07 28.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 EMR70233.1 - 0.00077 19.2 0.8 0.0011 18.7 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 EMR70233.1 - 0.0018 17.7 0.1 0.0064 15.9 0.1 1.8 1 1 0 1 1 1 1 Beta-galactosidase Hfq PF17209.3 EMR70233.1 - 0.019 14.6 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 Hfq protein LCAT PF02450.15 EMR70234.1 - 0.00084 18.6 0.0 0.005 16.1 0.0 1.9 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EMR70234.1 - 0.012 16.2 0.3 0.024 15.2 0.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR70234.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 EMR70234.1 - 0.027 14.1 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 EMR70234.1 - 0.028 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 EMR70234.1 - 0.17 11.3 0.0 0.48 9.9 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short PF00106.25 EMR70235.1 - 4e-48 163.5 1.4 4.7e-48 163.2 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70235.1 - 2.3e-46 158.2 1.6 3e-46 157.9 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70235.1 - 8e-13 48.7 3.0 2.1e-12 47.3 3.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR70235.1 - 1.6e-06 27.8 0.5 2.6e-06 27.1 0.5 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR70235.1 - 0.0047 16.4 0.0 0.008 15.6 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 EMR70235.1 - 0.0092 16.4 0.2 0.017 15.5 0.2 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding PALP PF00291.25 EMR70235.1 - 0.016 14.7 0.4 0.021 14.2 0.4 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 EMR70235.1 - 0.028 13.8 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EMR70235.1 - 0.032 13.6 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain B12-binding PF02310.19 EMR70235.1 - 0.051 13.6 0.3 0.079 13.0 0.3 1.4 1 0 0 1 1 1 0 B12 binding domain ApbA PF02558.16 EMR70235.1 - 0.078 12.6 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.26 EMR70235.1 - 0.084 12.8 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 EMR70235.1 - 0.11 12.4 0.3 0.25 11.2 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 EMR70235.1 - 0.11 12.0 0.3 0.24 10.9 0.3 1.6 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EMR70235.1 - 0.18 10.9 1.4 0.53 9.3 0.4 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain SAP18 PF06487.12 EMR70237.1 - 2.2e-31 108.9 0.0 8.9e-30 103.7 0.0 2.0 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) RPN7 PF10602.9 EMR70238.1 - 1.2e-36 126.0 0.0 2.7e-36 124.9 0.0 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EMR70238.1 - 1.5e-14 54.4 0.0 3.3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain Ntox35 PF15534.6 EMR70238.1 - 0.027 14.9 0.1 0.72 10.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial toxin 35 DUF357 PF04010.13 EMR70238.1 - 0.065 13.3 0.1 25 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF357) HEPN_SAV_6107 PF18726.1 EMR70238.1 - 0.36 11.4 1.8 17 6.0 0.3 2.4 2 0 0 2 2 2 0 SAV_6107-like HEPN Acetyltransf_1 PF00583.25 EMR70240.1 - 4.1e-11 43.1 0.1 5.2e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR70240.1 - 1.1e-08 35.3 0.2 1.7e-08 34.7 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR70240.1 - 3.1e-08 33.6 0.0 4.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rubredoxin_C PF18267.1 EMR70240.1 - 0.068 13.1 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain LRR_4 PF12799.7 EMR70241.1 - 0.052 14.0 0.8 8.7 6.9 0.6 4.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) NDUF_B4 PF07225.12 EMR70242.1 - 0.083 12.8 0.0 0.09 12.7 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Lipase_3 PF01764.25 EMR70243.1 - 2.6e-16 59.8 0.1 6.2e-12 45.6 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 EMR70243.1 - 0.0092 16.6 1.2 0.012 16.2 0.4 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR70243.1 - 0.035 13.4 0.1 0.061 12.6 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 2OG-FeII_Oxy_3 PF13640.6 EMR70245.1 - 5e-10 40.1 0.1 1.1e-09 39.1 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NUDIX PF00293.28 EMR70246.1 - 9.9e-23 80.6 0.7 1.2e-22 80.3 0.7 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EMR70246.1 - 0.0061 16.5 0.1 0.0082 16.1 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain Prp18 PF02840.15 EMR70247.1 - 4e-53 179.3 0.1 4e-53 179.3 0.1 2.4 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EMR70247.1 - 3e-11 42.7 7.1 3e-11 42.7 7.1 2.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like DUF966 PF06136.13 EMR70247.1 - 1.2 8.8 16.0 0.18 11.5 10.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF966) DAO PF01266.24 EMR70248.1 - 1.6e-28 100.3 0.2 2.2e-28 99.9 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR70248.1 - 0.016 14.2 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMR70248.1 - 0.023 14.9 0.1 0.074 13.3 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMR70248.1 - 0.049 13.6 1.4 2 8.4 0.1 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMR70248.1 - 0.13 11.5 0.0 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PhnA_Zn_Ribbon PF08274.12 EMR70250.1 - 1.6 8.7 5.8 0.4 10.7 1.1 2.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 EMR70250.1 - 8.2 6.0 7.8 22 4.6 0.9 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding GST_N PF02798.20 EMR70251.1 - 2e-12 47.3 0.0 3.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR70251.1 - 1.1e-07 32.1 0.0 2.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMR70251.1 - 1.1e-06 28.9 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR70251.1 - 4e-06 26.9 0.1 9.6e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR70251.1 - 9e-06 25.8 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR70251.1 - 0.00035 20.5 0.0 0.0011 19.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMR70251.1 - 0.035 14.7 0.0 0.082 13.5 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_1 PF00561.20 EMR70252.1 - 4.6e-05 23.2 0.1 6.8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EMR70252.1 - 5.7e-05 22.8 0.0 9.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 EMR70252.1 - 7.8e-05 21.7 0.1 0.0022 16.8 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.8 EMR70252.1 - 8.4e-05 21.9 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EMR70252.1 - 0.0025 17.5 0.0 0.0065 16.2 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EMR70252.1 - 0.0073 15.8 0.1 0.027 14.0 0.1 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.14 EMR70252.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Sugar_tr PF00083.24 EMR70253.1 - 2.6e-31 109.0 8.7 7.7e-22 77.8 0.1 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter Pam17 PF08566.10 EMR70253.1 - 0.069 13.0 1.9 0.69 9.7 0.2 2.4 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 Cwf_Cwc_15 PF04889.12 EMR70254.1 - 0.35 10.6 3.5 0.52 10.0 3.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein IBR PF01485.21 EMR70255.1 - 2.7e-14 53.1 16.6 6e-14 52.0 2.9 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Vmethyltransf PF01660.17 EMR70255.1 - 0.13 11.1 0.1 0.23 10.3 0.1 1.4 1 0 0 1 1 1 0 Viral methyltransferase IHO1 PF15771.5 EMR70255.1 - 0.33 9.7 12.1 0.5 9.1 12.1 1.2 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 c-SKI_SMAD_bind PF08782.10 EMR70255.1 - 1.4 9.2 9.2 0.14 12.4 1.4 2.5 2 1 0 2 2 2 0 c-SKI Smad4 binding domain zf-ribbon_3 PF13248.6 EMR70255.1 - 4.6 6.8 9.0 11 5.6 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain ALMT PF11744.8 EMR70255.1 - 7.9 5.2 6.8 11 4.7 6.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Pyridox_ox_2 PF12900.7 EMR70256.1 - 2.4e-33 115.1 0.0 3.3e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase p450 PF00067.22 EMR70257.1 - 2.4e-64 217.8 0.0 3.1e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.21 EMR70258.1 - 1.2e-83 281.7 0.1 1.2e-80 271.7 0.0 2.1 2 0 0 2 2 2 2 Amidase HSP70 PF00012.20 EMR70259.1 - 3.3e-14 52.0 0.0 1.2e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein FGGY_C PF02782.16 EMR70259.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain VapB_antitoxin PF09957.9 EMR70259.1 - 0.079 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB Aldo_ket_red PF00248.21 EMR70263.1 - 6e-54 183.2 0.0 6.8e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AdoHcyase PF05221.17 EMR70263.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Methyltransf_16 PF10294.9 EMR70264.1 - 1.5e-13 50.8 0.0 2.6e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EMR70264.1 - 0.0078 16.9 0.0 0.041 14.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR70264.1 - 0.0089 16.7 0.0 0.024 15.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR70264.1 - 0.012 15.2 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EMR70264.1 - 0.087 12.6 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Spermine_synth PF01564.17 EMR70265.1 - 3.5e-06 26.6 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 EMR70265.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EMR70265.1 - 0.1 13.3 0.0 0.27 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_S41 PF03572.18 EMR70266.1 - 8.5e-07 28.7 0.0 4.6e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 Glyco_hydro_47 PF01532.20 EMR70267.1 - 1.7e-117 393.1 0.0 2.6e-117 392.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2334 PF10096.9 EMR70267.1 - 0.0023 17.6 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Rad10 PF03834.14 EMR70268.1 - 1.4e-12 47.6 0.2 2.1e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EMR70268.1 - 0.0002 21.9 0.0 0.00048 20.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain SART-1 PF03343.13 EMR70268.1 - 0.006 15.2 7.1 0.0071 15.0 7.1 1.1 1 0 0 1 1 1 1 SART-1 family GAGE PF05831.11 EMR70268.1 - 0.11 13.1 7.6 0.17 12.4 7.6 1.3 1 0 0 1 1 1 0 GAGE protein SMP PF04927.12 EMR70270.1 - 0.00032 21.1 9.6 2.1 8.9 0.9 4.0 2 2 2 4 4 4 4 Seed maturation protein TMF_DNA_bd PF12329.8 EMR70271.1 - 0.00035 20.5 6.0 0.00035 20.5 6.0 8.2 5 2 3 8 8 8 3 TATA element modulatory factor 1 DNA binding Occludin_ELL PF07303.13 EMR70271.1 - 0.056 14.2 0.2 0.056 14.2 0.2 6.8 2 2 2 5 5 5 0 Occludin homology domain Fib_alpha PF08702.10 EMR70271.1 - 1.8 8.7 60.8 0.12 12.5 9.8 5.9 1 1 6 7 7 7 0 Fibrinogen alpha/beta chain family Es2 PF09751.9 EMR70272.1 - 1.6e-129 433.4 11.6 2.1e-129 433.1 11.6 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 UCH PF00443.29 EMR70273.1 - 6e-24 84.9 0.0 8.8e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EMR70273.1 - 8.1e-13 48.5 0.2 1.4e-12 47.8 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EMR70273.1 - 0.052 13.1 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Rxt3 PF08642.10 EMR70275.1 - 6.3e-46 156.3 0.5 1.8e-45 154.8 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EMR70275.1 - 8.2e-08 32.3 0.0 4.8e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 LCCL domain ADH_zinc_N PF00107.26 EMR70277.1 - 1.9e-09 37.6 0.8 3e-09 36.9 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR70277.1 - 1.4e-07 31.4 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SLATT_fungal PF18142.1 EMR70278.1 - 1.3e-28 99.4 0.2 1.7e-28 99.0 0.2 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain DUF4231 PF14015.6 EMR70278.1 - 0.0033 17.9 0.0 0.0053 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) UPF0114 PF03350.16 EMR70278.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 DUF3824 PF12868.7 EMR70279.1 - 0.00025 21.7 2.3 0.00025 21.7 2.3 1.4 2 0 0 2 2 2 1 Domain of unknwon function (DUF3824) ATP-synt_E PF05680.12 EMR70279.1 - 0.054 13.8 2.4 0.082 13.3 2.4 1.4 1 1 0 1 1 1 0 ATP synthase E chain RTA1 PF04479.13 EMR70280.1 - 3.3e-71 239.2 2.2 4.8e-71 238.6 2.2 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF5534 PF17686.1 EMR70280.1 - 0.047 14.0 0.6 0.13 12.5 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5534) Adaptin_N PF01602.20 EMR70281.1 - 2.5e-94 316.7 12.4 4.2e-94 316.0 12.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EMR70281.1 - 1.4e-60 203.2 0.9 3.1e-60 202.1 0.9 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EMR70281.1 - 1.4e-56 190.0 0.0 3.7e-56 188.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EMR70281.1 - 1.1e-13 51.6 5.9 5.7e-10 39.5 0.0 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMR70281.1 - 1.4e-08 35.0 2.8 8.5e-05 22.9 0.0 4.6 2 2 2 4 4 4 2 HEAT repeats Coatomer_g_Cpla PF16381.5 EMR70281.1 - 4.4e-05 23.6 0.0 0.00017 21.7 0.0 2.1 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EMR70281.1 - 0.0016 18.6 0.4 1 9.8 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat AP4E_app_platf PF14807.6 EMR70281.1 - 0.029 14.7 0.2 0.095 13.1 0.2 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 EMR70281.1 - 0.052 14.1 4.6 3.8 8.1 0.0 4.6 6 0 0 6 6 6 0 HEAT-like repeat GMC_oxred_C PF05199.13 EMR70282.1 - 4.2e-29 101.9 0.0 7.2e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR70282.1 - 2.3e-16 60.1 0.0 3.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Myb_DNA-bind_2 PF08914.11 EMR70282.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Rap1 Myb domain Pkinase PF00069.25 EMR70283.1 - 1.5e-57 195.0 0.0 2.1e-56 191.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR70283.1 - 3e-26 92.2 0.3 8.7e-20 71.1 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EMR70283.1 - 6.4e-05 22.1 0.1 9.6e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMR70283.1 - 0.00076 18.9 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMR70283.1 - 0.00088 18.7 0.7 0.002 17.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EMR70283.1 - 0.0067 16.4 2.9 0.038 13.9 0.3 2.6 2 1 0 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EMR70283.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EMR70283.1 - 0.82 9.2 3.6 0.62 9.6 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Cyclin PF08613.11 EMR70284.1 - 1.4e-08 35.2 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EMR70284.1 - 0.0029 17.4 0.1 0.006 16.3 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Nefa_Nip30_N PF10187.9 EMR70285.1 - 9.2e-32 109.5 5.2 9.2e-32 109.5 5.2 2.4 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Pec_lyase_C PF00544.19 EMR70286.1 - 7.4e-25 87.8 0.8 1e-24 87.3 0.8 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EMR70286.1 - 0.27 11.1 2.7 0.69 9.8 2.7 1.7 1 1 0 1 1 1 0 Right handed beta helix region Tim54 PF11711.8 EMR70287.1 - 3.8e-135 450.5 0.1 1.3e-134 448.7 0.1 1.7 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SatRNA_48 PF17485.2 EMR70287.1 - 0.19 10.8 0.1 0.29 10.2 0.1 1.2 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein SF3A2 PF16835.5 EMR70288.1 - 8.7e-37 125.4 0.0 1.2e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EMR70288.1 - 4.2e-06 27.0 0.9 7.2e-06 26.2 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EMR70288.1 - 0.012 15.6 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 EMR70288.1 - 0.068 12.7 1.5 0.12 12.0 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GBP PF02263.19 EMR70289.1 - 0.12 11.6 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain NAD_binding_8 PF13450.6 EMR70292.1 - 3.5e-10 40.0 0.1 1e-09 38.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR70292.1 - 6.7e-08 32.3 6.6 1e-07 31.7 0.0 2.4 3 0 0 3 3 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR70292.1 - 2.7e-05 23.4 1.8 2.7e-05 23.4 1.8 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR70292.1 - 3.2e-05 23.3 0.1 0.00058 19.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR70292.1 - 7.8e-05 22.1 1.4 0.02 14.1 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 EMR70292.1 - 0.00011 21.7 0.0 0.00031 20.1 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EMR70292.1 - 0.00013 21.6 2.4 0.00013 21.6 2.4 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR70292.1 - 0.00048 19.0 2.8 0.00053 18.8 1.4 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EMR70292.1 - 0.00067 19.0 0.9 0.0015 17.9 0.9 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EMR70292.1 - 0.0022 17.2 0.7 0.0035 16.5 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMR70292.1 - 0.0027 17.0 0.2 0.0043 16.3 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR70292.1 - 0.0055 17.2 1.9 0.028 15.0 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR70292.1 - 0.017 14.2 0.4 1 8.4 0.2 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EMR70292.1 - 0.043 12.7 1.5 0.066 12.1 1.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase IlvN PF07991.12 EMR70292.1 - 0.083 12.5 0.1 0.58 9.7 0.2 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 EMR70292.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EMR70292.1 - 0.12 11.4 0.3 0.2 10.7 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EMR70292.1 - 0.2 10.9 3.6 0.36 10.1 3.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pro_CA PF00484.19 EMR70294.1 - 1.9e-09 38.0 0.1 9.2e-06 26.0 0.1 2.5 1 1 1 2 2 2 2 Carbonic anhydrase Abhydrolase_6 PF12697.7 EMR70295.1 - 1.4e-16 61.8 3.0 1.8e-16 61.4 3.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR70295.1 - 2e-16 60.4 0.1 2.1e-15 57.1 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR70295.1 - 3e-15 56.1 0.0 5.3e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMR70295.1 - 0.00053 18.8 0.0 0.001 17.9 0.0 1.4 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 EMR70295.1 - 0.0075 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 EMR70295.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Esterase PF00756.20 EMR70295.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 EMR70295.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 EMR70295.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.13 EMR70295.1 - 0.22 11.2 0.1 0.35 10.6 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 EMR70295.1 - 0.22 10.5 0.0 0.55 9.2 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase Adaptin_N PF01602.20 EMR70296.1 - 8e-48 163.3 0.0 2e-32 112.5 0.1 2.9 2 1 1 3 3 3 3 Adaptin N terminal region HEAT_2 PF13646.6 EMR70296.1 - 0.011 16.1 0.7 0.45 10.9 0.0 2.9 2 1 1 3 3 3 0 HEAT repeats Sugar_tr PF00083.24 EMR70297.1 - 7.4e-90 302.0 24.8 8.7e-90 301.7 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR70297.1 - 6.6e-14 51.6 38.7 1.5e-09 37.2 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 EMR70298.1 - 7.6e-56 190.2 3.3 3.7e-54 184.6 3.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR70298.1 - 3.8e-06 27.4 0.0 0.022 15.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR70298.1 - 1.2e-05 25.4 1.3 3.4e-05 24.0 1.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR70298.1 - 2.4e-05 23.7 0.5 0.015 14.6 0.0 2.9 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EMR70298.1 - 0.00072 18.5 2.2 0.042 12.6 0.5 2.5 3 0 0 3 3 3 2 MCRA family NAD_binding_9 PF13454.6 EMR70298.1 - 0.0016 18.5 0.4 0.011 15.7 0.1 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EMR70298.1 - 0.1 11.5 0.1 0.36 9.6 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Ribosomal_60s PF00428.19 EMR70298.1 - 2.7 8.7 11.5 3.8 8.2 1.2 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein CBM_4_9 PF02018.17 EMR70300.1 - 0.00088 19.6 0.1 0.0022 18.2 0.1 1.7 1 1 0 1 1 1 1 Carbohydrate binding domain HA2 PF04408.23 EMR70301.1 - 4.8e-25 88.0 0.0 4.8e-25 88.0 0.0 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMR70301.1 - 1.8e-11 44.4 0.0 7.2e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMR70301.1 - 1.8e-11 44.2 0.0 6e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EMR70301.1 - 1.2e-08 35.0 0.0 7.6e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EMR70301.1 - 0.00057 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMR70301.1 - 0.0011 19.3 0.0 0.0045 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMR70301.1 - 0.0015 18.3 0.1 0.0045 16.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMR70301.1 - 0.0058 17.1 0.0 0.0058 17.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 EMR70301.1 - 0.016 14.3 0.0 0.043 12.9 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EMR70301.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.18 EMR70301.1 - 0.029 13.7 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family PhoH PF02562.16 EMR70301.1 - 0.037 13.5 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EMR70301.1 - 0.04 13.5 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3246 PF11596.8 EMR70301.1 - 0.042 13.3 3.9 0.081 12.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) ResIII PF04851.15 EMR70301.1 - 0.057 13.4 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_pol_Rpc4 PF05132.14 EMR70302.1 - 1.1e-27 97.3 0.2 1.1e-27 97.3 0.2 4.3 3 3 1 4 4 4 1 RNA polymerase III RPC4 STAG PF08514.11 EMR70303.1 - 1.4e-34 118.4 0.1 4e-34 116.9 0.1 1.9 1 0 0 1 1 1 1 STAG domain Cnd1 PF12717.7 EMR70303.1 - 0.0014 18.7 0.1 0.72 9.9 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EMR70303.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 CLASP N terminal FAD_binding_3 PF01494.19 EMR70304.1 - 2.4e-09 36.9 0.0 9.9e-09 34.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR70304.1 - 2.1e-06 27.9 0.0 2.3e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR70304.1 - 0.00071 19.3 0.6 0.0024 17.5 0.1 2.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR70304.1 - 0.0016 17.7 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR70304.1 - 0.058 14.0 0.0 0.21 12.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR70304.1 - 0.082 12.1 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EMR70304.1 - 0.1 11.6 0.1 0.19 10.7 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EMR70304.1 - 0.13 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EMR70304.1 - 0.22 10.7 0.0 0.45 9.7 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Med6 PF04934.14 EMR70305.1 - 2.4e-37 127.7 0.0 3.3e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Methyltransf_2 PF00891.18 EMR70306.1 - 1.2e-17 63.9 0.0 2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EMR70306.1 - 0.00022 21.2 0.1 0.00045 20.2 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain DIOX_N PF14226.6 EMR70307.1 - 2.7e-23 82.9 0.0 3.5e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HAD_2 PF13419.6 EMR70308.1 - 1.6e-13 51.1 0.0 3.2e-11 43.6 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR70308.1 - 7.6e-05 23.1 0.0 0.00013 22.4 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR70308.1 - 0.00025 21.0 0.0 0.00059 19.8 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Peptidase_M28 PF04389.17 EMR70309.1 - 4.1e-27 95.2 0.1 1.3e-26 93.5 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EMR70309.1 - 3.2e-07 30.3 0.0 5.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EMR70309.1 - 0.0017 17.4 0.0 0.0035 16.4 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase fn3 PF00041.21 EMR70309.1 - 0.0039 17.5 0.0 0.0084 16.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Tape_meas_lam_C PF09718.10 EMR70310.1 - 0.013 15.6 0.1 0.059 13.5 0.0 2.1 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ArfGap PF01412.18 EMR70310.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Glyco_hydro_61 PF03443.14 EMR70311.1 - 5.4e-48 163.7 0.0 6.3e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GATase PF00117.28 EMR70312.1 - 3.2e-47 160.8 0.0 4.3e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EMR70312.1 - 1e-46 157.9 0.0 2.1e-46 156.9 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EMR70312.1 - 5e-06 26.4 0.6 0.0012 18.7 0.4 3.2 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 EMR70312.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family AAA_6 PF12774.7 EMR70314.1 - 2.8e-126 420.9 0.0 1.4e-125 418.6 0.0 2.4 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EMR70314.1 - 3.4e-118 395.7 20.6 3.4e-118 395.7 20.6 4.6 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EMR70314.1 - 2.6e-116 389.0 6.5 2.6e-116 389.0 6.5 5.7 4 1 1 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EMR70314.1 - 8.6e-73 244.1 1.3 8.6e-73 244.1 1.3 3.9 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EMR70314.1 - 3e-66 223.4 0.0 2.6e-65 220.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EMR70314.1 - 1.7e-41 141.7 0.0 5.3e-36 123.8 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EMR70314.1 - 2.6e-37 128.7 10.7 4.1e-37 128.0 6.4 2.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EMR70314.1 - 1e-30 106.5 0.0 1.5e-11 44.4 0.0 6.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EMR70314.1 - 2.7e-30 104.9 0.3 1.4e-27 96.2 0.0 4.2 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EMR70314.1 - 3.8e-27 95.1 0.0 9.9e-27 93.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 EMR70314.1 - 7.3e-15 55.2 0.1 5.7e-14 52.3 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EMR70314.1 - 1.8e-14 54.2 2.3 0.0097 16.2 0.0 6.2 5 1 0 5 5 4 3 AAA domain AAA PF00004.29 EMR70314.1 - 5e-13 49.6 0.0 0.0023 18.3 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EMR70314.1 - 6.8e-10 39.3 0.8 0.32 11.2 0.0 5.3 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 EMR70314.1 - 1.2e-09 38.8 0.3 0.04 14.5 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 EMR70314.1 - 3.4e-09 37.3 5.1 1.8 8.9 0.0 7.7 7 0 0 7 7 5 2 AAA ATPase domain AAA_29 PF13555.6 EMR70314.1 - 8.2e-06 25.5 0.1 0.66 9.8 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EMR70314.1 - 2.8e-05 23.6 0.8 0.68 9.3 0.0 4.5 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EMR70314.1 - 6e-05 22.2 0.0 0.045 12.8 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 EMR70314.1 - 0.00011 22.3 0.0 0.0012 19.0 0.0 2.8 2 0 0 2 2 2 1 AAA+ lid domain ABC_tran PF00005.27 EMR70314.1 - 0.00012 22.6 0.1 6.4 7.3 0.0 4.8 3 0 0 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.18 EMR70314.1 - 0.0011 18.4 2.5 2.4 7.4 0.0 4.4 4 0 0 4 4 4 1 FtsK/SpoIIIE family AAA_30 PF13604.6 EMR70314.1 - 0.0014 18.4 0.5 39 3.9 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 EMR70314.1 - 0.005 16.6 1.4 11 5.7 0.0 4.4 5 0 0 5 5 3 0 AAA domain AAA_25 PF13481.6 EMR70314.1 - 0.0056 16.3 3.7 0.25 10.9 0.0 4.0 4 0 0 4 4 2 1 AAA domain IstB_IS21 PF01695.17 EMR70314.1 - 0.0058 16.4 0.4 0.67 9.7 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein Rad17 PF03215.15 EMR70314.1 - 0.012 15.6 0.0 6.9 6.5 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain RNA_helicase PF00910.22 EMR70314.1 - 0.012 16.0 0.1 51 4.3 0.0 4.7 4 0 0 4 4 4 0 RNA helicase Zeta_toxin PF06414.12 EMR70314.1 - 0.013 14.8 0.1 7.8 5.7 0.1 4.1 4 0 0 4 4 4 0 Zeta toxin AAA_19 PF13245.6 EMR70314.1 - 0.043 14.2 9.0 0.28 11.5 0.0 5.1 6 0 0 6 6 4 0 AAA domain ERM PF00769.19 EMR70314.1 - 0.14 12.0 28.8 0.065 13.0 10.5 4.1 3 0 0 3 3 3 0 Ezrin/radixin/moesin family MEDS PF14417.6 EMR70314.1 - 0.17 11.7 3.7 0.67 9.8 0.4 3.6 3 0 0 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain NACHT PF05729.12 EMR70314.1 - 0.23 11.3 4.0 32 4.4 0.0 4.5 4 0 0 4 4 3 0 NACHT domain COG2 PF06148.11 EMR70314.1 - 0.92 9.6 0.0 0.92 9.6 0.0 6.0 5 0 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_17 PF13207.6 EMR70314.1 - 2.3 8.6 4.7 1.5e+02 2.8 0.0 4.8 4 0 0 4 4 4 0 AAA domain UCH PF00443.29 EMR70314.1 - 5.3 6.4 5.1 41 3.6 0.0 4.0 5 1 0 5 5 4 0 Ubiquitin carboxyl-terminal hydrolase Phage_GP20 PF06810.11 EMR70314.1 - 6 6.7 19.6 1 9.2 7.4 3.9 3 0 0 3 3 2 0 Phage minor structural protein GP20 DUF4482 PF14818.6 EMR70314.1 - 6.3 7.7 13.7 37 5.2 0.0 3.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4482) Golgin_A5 PF09787.9 EMR70316.1 - 8e-05 22.2 1.7 9e-05 22.1 1.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF737 PF05300.11 EMR70316.1 - 0.0056 17.1 1.9 0.006 17.0 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF737) TBCA PF02970.16 EMR70316.1 - 0.0059 16.9 2.6 0.0094 16.3 2.6 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A Tektin PF03148.14 EMR70316.1 - 0.0075 15.1 5.7 0.0093 14.8 5.7 1.1 1 0 0 1 1 1 1 Tektin family Spc7 PF08317.11 EMR70316.1 - 0.0084 15.0 1.3 0.0093 14.9 1.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein BBP1_C PF15272.6 EMR70316.1 - 0.01 15.7 1.6 0.012 15.5 1.6 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Med9 PF07544.13 EMR70316.1 - 0.011 15.8 5.4 0.023 14.8 5.4 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF16 PF01519.16 EMR70316.1 - 0.022 15.3 2.0 0.039 14.4 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 HIP1_clath_bdg PF16515.5 EMR70316.1 - 0.026 15.1 2.7 0.052 14.2 2.7 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc29 PF17082.5 EMR70316.1 - 0.028 14.3 2.1 0.037 13.9 1.8 1.3 1 1 0 1 1 1 0 Spindle Pole Component 29 DUF262 PF03235.14 EMR70316.1 - 0.044 14.0 1.1 0.05 13.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Prefoldin_2 PF01920.20 EMR70316.1 - 0.053 13.5 4.6 0.099 12.6 4.6 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.12 EMR70316.1 - 0.075 13.1 0.8 0.28 11.2 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nnf1 PF03980.14 EMR70316.1 - 0.19 12.2 4.6 0.55 10.6 3.4 2.1 2 1 0 2 2 2 0 Nnf1 YtxH PF12732.7 EMR70316.1 - 0.25 11.9 3.7 0.44 11.1 3.7 1.4 1 0 0 1 1 1 0 YtxH-like protein LMBR1 PF04791.16 EMR70316.1 - 0.36 9.7 0.2 0.38 9.6 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Wyosine_form PF08608.12 EMR70317.1 - 7.9e-23 80.6 0.0 1.1e-21 76.9 0.0 2.5 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.21 EMR70317.1 - 9.4e-22 78.2 0.1 3.5e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EMR70317.1 - 3.5e-08 33.8 0.2 4.9e-07 30.0 0.2 2.3 1 1 0 1 1 1 1 Flavodoxin MSC PF09402.10 EMR70317.1 - 0.06 12.8 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF4381 PF14316.6 EMR70318.1 - 0.15 12.3 0.6 0.32 11.2 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pox_I5 PF04713.12 EMR70318.1 - 0.82 9.8 4.8 2.3 8.3 0.1 3.2 4 0 0 4 4 4 0 Poxvirus protein I5 MAS20 PF02064.15 EMR70319.1 - 5e-39 133.3 0.8 6e-39 133.1 0.8 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor DUF429 PF04250.13 EMR70319.1 - 0.045 13.6 0.7 2.8 7.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF429) DUF630 PF04783.12 EMR70319.1 - 0.76 10.0 3.4 0.48 10.6 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Metallophos PF00149.28 EMR70320.1 - 7.1e-38 131.2 0.5 1.2e-37 130.5 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMR70320.1 - 0.013 15.9 0.1 0.026 15.0 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EMR70320.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF3112 PF11309.8 EMR70321.1 - 0.0025 17.3 0.6 0.0048 16.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) AveC_like PF17198.4 EMR70321.1 - 0.0085 15.6 1.5 0.019 14.4 1.5 1.5 1 0 0 1 1 1 1 Spirocyclase AveC-like DUF898 PF05987.13 EMR70321.1 - 0.019 14.0 6.1 0.027 13.5 0.0 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF898) DUF2070 PF09843.9 EMR70321.1 - 0.056 11.7 3.9 0.1 10.8 3.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) MIG-14_Wnt-bd PF06664.12 EMR70321.1 - 0.14 11.4 2.9 0.22 10.7 2.9 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion GlgS PF08971.11 EMR70321.1 - 0.14 12.2 0.5 0.53 10.3 0.1 2.1 2 0 0 2 2 2 0 Glycogen synthesis protein Yip1 PF04893.17 EMR70321.1 - 0.15 11.8 12.5 0.26 11.0 4.4 2.6 1 1 1 2 2 2 0 Yip1 domain COPI_assoc PF08507.10 EMR70323.1 - 1.5e-33 115.7 4.2 1.7e-33 115.4 4.2 1.0 1 0 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.9 EMR70323.1 - 0.013 14.9 1.4 0.027 13.8 1.4 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF2371 PF10177.9 EMR70323.1 - 0.23 11.6 2.6 5.2 7.2 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Cytochrom_B558a PF05038.13 EMR70323.1 - 8.9 5.8 7.1 20 4.7 7.1 1.8 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Neurensin PF14927.6 EMR70323.1 - 9.5 5.9 7.4 35 4.1 7.4 2.2 1 1 0 1 1 1 0 Neurensin SAP PF02037.27 EMR70324.1 - 7.7e-14 51.1 0.3 1.5e-13 50.1 0.3 1.5 1 0 0 1 1 1 1 SAP domain ETF PF01012.21 EMR70325.1 - 2.1e-44 151.6 2.4 2.5e-44 151.4 2.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Acetyltransf_1 PF00583.25 EMR70326.1 - 1.4e-07 31.7 0.0 2.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR70326.1 - 0.062 13.2 0.1 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CPBP PF02517.16 EMR70326.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease Pho86 PF11124.8 EMR70326.1 - 0.14 11.6 1.8 0.27 10.6 1.3 1.7 2 1 0 2 2 2 0 Inorganic phosphate transporter Pho86 CENP-T_C PF15511.6 EMR70327.1 - 0.058 13.5 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Exo84_C PF16528.5 EMR70328.1 - 2.6e-75 252.7 1.4 2.6e-75 252.7 1.4 2.1 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EMR70328.1 - 7.8e-11 41.9 2.4 7.8e-11 41.9 2.4 2.2 2 0 0 2 2 2 1 Vps51/Vps67 DUF4407 PF14362.6 EMR70328.1 - 0.0067 15.8 2.1 0.026 13.9 2.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) DUF4047 PF13256.6 EMR70328.1 - 0.25 11.6 3.8 0.15 12.3 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) GldM_N PF12081.8 EMR70328.1 - 0.43 10.6 10.2 0.018 15.2 3.4 2.0 2 1 0 2 2 2 0 GldM N-terminal domain COG2 PF06148.11 EMR70328.1 - 0.77 9.8 7.5 1.9 8.6 0.9 3.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TSC22 PF01166.18 EMR70328.1 - 1.2 9.5 5.3 17 5.8 0.0 3.3 4 0 0 4 4 4 0 TSC-22/dip/bun family Baculo_PEP_C PF04513.12 EMR70328.1 - 1.4 8.9 5.9 3.1 7.8 0.4 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc24 PF08286.11 EMR70328.1 - 2.4 8.4 5.9 0.42 10.9 0.5 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Sec5 PF15469.6 EMR70328.1 - 3.2 7.5 8.9 9.4 6.0 1.8 2.6 3 0 0 3 3 3 0 Exocyst complex component Sec5 PI3_PI4_kinase PF00454.27 EMR70330.1 - 3.8e-52 177.6 0.0 7e-52 176.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EMR70330.1 - 1.8e-16 59.6 0.0 4.2e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain UME PF08064.13 EMR70330.1 - 6.5e-15 54.9 0.9 7.6e-14 51.5 0.1 3.2 3 0 0 3 3 3 1 UME (NUC010) domain FAT PF02259.23 EMR70330.1 - 8.1e-05 22.0 0.8 0.049 12.8 0.1 2.8 2 1 1 3 3 3 2 FAT domain TPR_19 PF14559.6 EMR70330.1 - 0.089 13.3 0.0 0.34 11.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat FANCI_HD1 PF14679.6 EMR70330.1 - 0.13 12.2 1.1 63 3.6 0.0 3.7 3 0 0 3 3 3 0 FANCI helical domain 1 zf-PARP PF00645.18 EMR70331.1 - 9.6e-26 90.5 1.4 2.2e-25 89.3 1.4 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DTHCT PF08070.11 EMR70331.1 - 0.029 15.1 43.3 0.029 15.1 23.5 3.7 2 1 0 2 2 2 0 DTHCT (NUC029) region Neuregulin PF02158.15 EMR70331.1 - 0.21 10.9 7.3 0.26 10.6 7.3 1.2 1 0 0 1 1 1 0 Neuregulin intracellular region PGI PF00342.19 EMR70333.1 - 1.2e-44 152.8 0.0 1.3e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase MFS_1 PF07690.16 EMR70335.1 - 2.8e-13 49.5 10.4 2.6e-12 46.4 11.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR70335.1 - 9.5e-05 21.4 3.5 0.00012 21.1 0.8 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter CLN3 PF02487.17 EMR70335.1 - 0.045 12.8 0.0 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 CLN3 protein AA_permease_2 PF13520.6 EMR70336.1 - 3.5e-53 181.0 26.0 4.2e-53 180.7 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR70336.1 - 2.2e-10 39.7 23.2 2.8e-10 39.4 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_C69 PF03577.15 EMR70338.1 - 1e-17 64.2 0.0 1.5e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 adh_short_C2 PF13561.6 EMR70339.1 - 1.1e-28 100.5 0.8 1.3e-19 70.7 1.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR70339.1 - 2.1e-20 73.0 0.2 2.7e-20 72.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR70339.1 - 4.1e-07 30.1 0.1 5.9e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR70339.1 - 0.094 11.8 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EMR70340.1 - 6.7e-17 61.4 15.6 7.6e-16 58.0 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_beta PF03977.13 EMR70340.1 - 0.0071 15.4 0.8 0.014 14.4 0.4 1.5 1 1 0 1 1 1 1 Na+-transporting oxaloacetate decarboxylase beta subunit DUF2070 PF09843.9 EMR70340.1 - 2.1 6.5 7.1 3.4 5.9 7.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1774 PF08611.10 EMR70342.1 - 5.5e-38 129.2 4.9 5.5e-38 129.2 4.9 2.7 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) PS-DH PF14765.6 EMR70343.1 - 4e-71 239.7 0.0 6e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EMR70343.1 - 1.8e-64 217.7 0.0 4.3e-64 216.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EMR70343.1 - 5.6e-58 195.8 0.2 1.6e-57 194.4 0.2 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EMR70343.1 - 5e-55 187.2 0.1 8.9e-55 186.4 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR70343.1 - 9.1e-23 80.5 1.6 7.9e-22 77.5 0.3 2.7 1 1 1 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR70343.1 - 6.8e-17 61.9 0.0 2.5e-16 60.1 0.0 2.1 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EMR70343.1 - 4.8e-09 36.0 0.1 1.3e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EMR70343.1 - 9.3e-06 25.6 2.0 2.9e-05 24.0 0.1 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR70343.1 - 0.00013 21.8 0.2 0.00037 20.4 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EMR70343.1 - 0.00017 21.9 0.1 0.0045 17.3 0.0 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 EMR70343.1 - 0.076 12.9 0.4 0.3 11.0 0.4 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pyr_redox_3 PF13738.6 EMR70344.1 - 1.1e-10 41.3 0.0 1e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMR70344.1 - 5.1e-10 38.4 0.0 3.1e-06 25.9 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMR70344.1 - 3.6e-08 32.9 0.1 3.4e-06 26.5 0.0 3.0 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMR70344.1 - 2.1e-06 27.2 0.0 0.0012 18.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR70344.1 - 0.00012 22.1 0.0 0.54 10.2 0.0 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 EMR70344.1 - 0.0029 16.9 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EMR70344.1 - 0.024 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Cyclase PF04199.13 EMR70344.1 - 0.036 14.3 0.0 8.5 6.6 0.0 3.2 3 0 0 3 3 3 0 Putative cyclase HI0933_like PF03486.14 EMR70344.1 - 0.052 12.2 0.0 1.5 7.4 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.6 EMR70344.1 - 0.066 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribonuclease_T2 PF00445.18 EMR70346.1 - 2.5e-34 119.1 0.1 3.4e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Sec62 PF03839.16 EMR70347.1 - 4.9e-73 245.2 0.5 4.9e-73 245.2 0.5 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 LIN37 PF15306.6 EMR70347.1 - 0.15 12.2 5.5 0.39 10.9 5.5 1.6 1 0 0 1 1 1 0 LIN37 YopE_N PF09020.10 EMR70347.1 - 0.35 11.1 2.3 0.77 10.0 2.3 1.5 1 0 0 1 1 1 0 YopE, N terminal DUF4199 PF13858.6 EMR70347.1 - 0.9 9.9 5.4 2.2 8.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF4834 PF16118.5 EMR70347.1 - 1.3 10.0 5.8 8 7.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Corona_M PF01635.18 EMR70347.1 - 5.6 6.2 7.8 8.4 5.6 7.8 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein DUF3632 PF12311.8 EMR70348.1 - 1.2e-06 29.1 0.1 1.4e-06 28.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Beta-lactamase PF00144.24 EMR70349.1 - 9.7e-55 186.1 0.2 1.3e-54 185.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EMR70349.1 - 0.0032 17.1 0.0 0.23 11.0 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase enzyme family Chorismate_synt PF01264.21 EMR70350.1 - 2.3e-138 460.4 0.0 2.6e-138 460.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Fil_haemagg PF05594.14 EMR70351.1 - 0.69 10.5 2.8 1.3 9.7 2.8 1.4 1 0 0 1 1 1 0 Haemagluttinin repeat Clathrin PF00637.20 EMR70352.1 - 6e-24 84.6 4.5 1.8e-22 79.8 3.2 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 EMR70352.1 - 7e-14 51.8 0.8 2.1e-06 27.8 0.1 2.8 2 0 0 2 2 2 2 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EMR70352.1 - 4e-07 30.0 1.9 1.1e-06 28.5 1.9 1.8 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 EMR70352.1 - 0.0032 17.4 0.2 0.0072 16.3 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMR70352.1 - 0.0036 17.1 1.1 0.0036 17.1 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 EMR70352.1 - 0.0043 16.7 0.1 0.012 15.2 0.1 1.8 1 0 0 1 1 1 1 TPR repeat zf-RING_UBOX PF13445.6 EMR70352.1 - 0.01 15.9 0.8 0.021 14.9 0.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger TPR_14 PF13428.6 EMR70352.1 - 0.01 16.6 0.7 4.1 8.5 0.5 3.9 2 1 1 3 3 2 0 Tetratricopeptide repeat DUF2935 PF11155.8 EMR70352.1 - 0.024 15.0 0.0 0.92 9.8 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) zf-ANAPC11 PF12861.7 EMR70352.1 - 0.035 14.2 0.4 0.097 12.7 0.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EMR70352.1 - 0.07 13.5 3.6 0.33 11.3 3.6 2.2 1 1 0 1 1 1 0 Ring finger domain DUF4810 PF16068.5 EMR70352.1 - 0.15 12.6 0.2 35 5.0 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) zf-C3HC4 PF00097.25 EMR70352.1 - 0.17 11.8 0.5 0.51 10.2 0.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EMR70352.1 - 0.85 9.9 2.9 1.3 9.3 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR70352.1 - 1.9 8.8 6.7 9.2 6.6 0.2 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-rbx1 PF12678.7 EMR70352.1 - 2.1 8.7 6.4 0.12 12.7 0.9 1.7 2 0 0 2 2 1 0 RING-H2 zinc finger domain TPR_12 PF13424.6 EMR70352.1 - 5 7.5 6.3 8.3 6.8 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3632 PF12311.8 EMR70353.1 - 2.6e-16 60.6 0.0 3.5e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Fungal_trans PF04082.18 EMR70354.1 - 4.3e-12 45.6 1.0 2.9e-07 29.8 0.9 2.3 1 1 0 2 2 2 2 Fungal specific transcription factor domain TatD_DNase PF01026.21 EMR70355.1 - 9e-36 123.5 0.0 6.8e-33 114.1 0.0 2.3 2 0 0 2 2 2 2 TatD related DNase Pex14_N PF04695.13 EMR70355.1 - 0.27 11.9 10.3 0.64 10.7 5.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GP40 PF11025.8 EMR70356.1 - 0.045 13.5 0.8 0.054 13.3 0.8 1.1 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium CENP-N PF05238.13 EMR70357.1 - 1.7e-135 452.5 0.0 2.1e-135 452.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like PBP1_TM PF14812.6 EMR70357.1 - 0.69 10.3 22.4 2.8 8.4 1.9 3.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribonuc_red_lgC PF02867.15 EMR70358.1 - 1.8e-190 634.0 0.0 2.5e-190 633.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EMR70358.1 - 7.4e-24 83.6 0.0 5.7e-23 80.7 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EMR70358.1 - 8.6e-17 61.5 0.0 1.7e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 ATP cone domain Glycos_transf_1 PF00534.20 EMR70359.1 - 1.3e-31 109.5 0.1 3.9e-29 101.4 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMR70359.1 - 3.1e-13 50.3 0.8 8.1e-13 49.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMR70359.1 - 1.8e-11 44.3 0.2 4.5e-11 43.0 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EMR70359.1 - 8.6e-06 26.3 2.0 8.6e-06 26.3 2.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 EMR70359.1 - 0.048 13.7 0.6 6.9 6.7 0.6 3.2 1 1 0 1 1 1 0 ALG11 mannosyltransferase N-terminus Glyco_trans_4_5 PF16994.5 EMR70359.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl-transferase family 4 MFS_1 PF07690.16 EMR70360.1 - 6.2e-44 150.4 38.2 1.4e-43 149.2 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR70360.1 - 7.9e-11 41.1 4.9 1.2e-10 40.4 4.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMR70360.1 - 0.00022 20.2 27.0 0.0017 17.3 27.0 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter bZIP_2 PF07716.15 EMR70361.1 - 1.2e-11 44.4 11.6 2.2e-11 43.7 11.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EMR70361.1 - 0.00075 19.6 15.6 0.0028 17.7 10.8 1.7 1 1 1 2 2 2 2 bZIP transcription factor APC_u14 PF16635.5 EMR70361.1 - 0.0029 18.1 4.2 0.005 17.3 4.2 1.3 1 0 0 1 1 1 1 Unstructured region on APC between SAMP and APC_crr GIT_CC PF16559.5 EMR70361.1 - 0.012 15.5 1.7 0.012 15.5 1.7 1.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 EMR70361.1 - 0.02 15.2 1.6 0.035 14.4 1.6 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 EMR70361.1 - 0.093 12.6 1.0 0.093 12.6 1.0 1.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region PsiA PF06952.11 EMR70361.1 - 0.096 11.9 2.9 0.12 11.6 2.9 1.1 1 0 0 1 1 1 0 PsiA protein Fib_alpha PF08702.10 EMR70361.1 - 0.31 11.2 3.2 0.4 10.9 3.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LCD1 PF09798.9 EMR70361.1 - 0.31 9.5 3.6 0.31 9.5 3.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein XhlA PF10779.9 EMR70361.1 - 0.36 11.1 3.0 0.6 10.3 3.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Macoilin PF09726.9 EMR70361.1 - 0.59 8.6 7.6 0.73 8.3 7.6 1.0 1 0 0 1 1 1 0 Macoilin family YabA PF06156.13 EMR70361.1 - 1.2 9.8 6.5 1.1 9.9 3.6 1.9 1 1 1 2 2 2 0 Initiation control protein YabA NAD_binding_4 PF07993.12 EMR70362.1 - 2.4e-28 99.0 0.0 3.6e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EMR70362.1 - 6.1e-11 42.2 0.0 8.6e-10 38.5 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 EMR70362.1 - 1.7e-10 40.1 0.0 3e-09 36.0 0.0 2.4 2 1 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 EMR70362.1 - 1.8e-06 28.2 0.1 5.7e-06 26.6 0.1 1.9 1 1 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EMR70362.1 - 0.00017 21.1 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EMR70362.1 - 0.00057 20.3 0.0 0.0016 18.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMR70362.1 - 0.051 12.6 0.0 4.5 6.2 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMR70362.1 - 0.065 12.4 0.0 0.81 8.8 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF3632 PF12311.8 EMR70363.1 - 2.7e-09 37.7 0.0 3.2e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Clr5 PF14420.6 EMR70364.1 - 1.7e-17 63.3 1.1 3.2e-17 62.5 0.4 1.9 2 0 0 2 2 2 1 Clr5 domain CN_hydrolase PF00795.22 EMR70364.1 - 1.5e-07 31.0 0.0 2.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HtrL_YibB PF09612.10 EMR70365.1 - 0.00072 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) DUF5521 PF17659.1 EMR70366.1 - 2.9 5.6 5.1 4.6 4.9 5.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Neur_chan_memb PF02932.16 EMR70366.1 - 4.9 7.1 10.8 3.5 7.6 5.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BPL_LplA_LipB PF03099.19 EMR70367.1 - 3.3e-06 27.0 0.0 5.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MutL_C PF08676.11 EMR70368.1 - 3.5e-05 23.6 0.0 0.0042 16.9 0.0 3.1 2 1 0 2 2 2 2 MutL C terminal dimerisation domain NmrA PF05368.13 EMR70369.1 - 7.2e-35 120.6 0.0 5.1e-32 111.3 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EMR70369.1 - 2e-13 50.7 0.0 2.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR70369.1 - 9.6e-06 25.2 0.0 1.9e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR70369.1 - 7.7e-05 21.8 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 EMR70369.1 - 0.021 15.6 0.0 0.049 14.3 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 EMR70369.1 - 0.11 12.8 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 EMR70370.1 - 4.4e-24 85.7 3.9 8.6e-24 84.8 3.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase PurS PF02700.14 EMR70370.1 - 0.032 14.4 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Pkinase PF00069.25 EMR70371.1 - 2.4e-49 168.1 0.0 1.8e-32 112.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR70371.1 - 1.3e-22 80.3 0.5 1.1e-19 70.8 0.5 3.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR70371.1 - 8.2e-05 22.0 0.0 0.00087 18.7 0.0 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EMR70371.1 - 0.0008 19.4 0.2 0.0048 16.9 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMR70371.1 - 0.011 14.5 0.1 0.036 12.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 EMR70371.1 - 0.031 13.2 0.1 0.077 11.9 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Fungal_trans PF04082.18 EMR70372.1 - 2.3e-10 40.0 0.0 2.3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nitroreductase PF00881.24 EMR70373.1 - 3.5e-10 40.2 0.0 5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family DRY_EERY PF09750.9 EMR70374.1 - 0.0005 20.3 1.1 0.00056 20.2 1.1 1.1 1 0 0 1 1 1 1 Alternative splicing regulator THOC7 PF05615.13 EMR70374.1 - 0.012 15.9 2.6 0.014 15.7 2.6 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 TarH PF02203.15 EMR70374.1 - 0.049 13.6 0.3 0.064 13.2 0.3 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue Laminin_II PF06009.12 EMR70374.1 - 0.075 13.0 4.0 0.095 12.7 4.0 1.0 1 0 0 1 1 1 0 Laminin Domain II DUF3500 PF12006.8 EMR70375.1 - 4.5e-99 331.7 0.0 5.4e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAD_binding_3 PF01494.19 EMR70376.1 - 6.9e-87 291.9 0.0 8.4e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR70376.1 - 7.9e-06 25.7 1.8 0.059 12.9 0.3 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR70376.1 - 0.00016 21.0 0.0 0.17 11.1 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR70376.1 - 0.015 15.5 0.4 0.041 14.1 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR70376.1 - 0.033 13.4 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EMR70376.1 - 0.045 14.3 0.0 2.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR70376.1 - 0.19 10.8 2.6 0.41 9.7 1.7 1.9 2 0 0 2 2 2 0 FAD binding domain Fib_alpha PF08702.10 EMR70377.1 - 0.04 14.1 5.3 0.52 10.5 0.6 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EcoR124_C PF12008.8 EMR70377.1 - 0.045 13.4 5.1 0.065 12.9 5.1 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal PNPase PF03726.14 EMR70377.1 - 0.11 13.0 1.9 0.24 11.9 1.9 1.6 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Peptidase_C65 PF10275.9 EMR70377.1 - 0.14 11.6 1.5 1.9 7.9 0.1 2.0 1 1 1 2 2 2 0 Peptidase C65 Otubain SesA PF17107.5 EMR70377.1 - 0.16 12.2 1.6 1.2 9.4 0.9 2.2 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF16 PF01519.16 EMR70377.1 - 1.2 9.6 8.9 1.1 9.8 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 EMR70377.1 - 4.1 7.9 6.8 17 5.9 1.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Melibiase_2 PF16499.5 EMR70378.1 - 1.6e-45 155.5 3.3 7.7e-33 113.9 0.5 2.9 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 EMR70378.1 - 7.6e-13 48.3 1.1 8e-12 45.1 0.0 2.7 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EMR70378.1 - 1.3e-06 27.6 0.0 2.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Melibiase CFEM PF05730.11 EMR70379.1 - 3.8e-11 42.9 5.5 6.6e-11 42.1 5.5 1.4 1 0 0 1 1 1 1 CFEM domain FAA_hydrolase PF01557.18 EMR70381.1 - 9e-67 224.9 0.0 1.1e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 EMR70381.1 - 0.00057 20.3 0.2 0.00098 19.5 0.2 1.3 1 0 0 1 1 1 1 Type II transport protein GspH Sugar_tr PF00083.24 EMR70383.1 - 1.6e-106 356.9 20.1 1.8e-106 356.7 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR70383.1 - 9e-30 103.8 30.7 1.3e-27 96.7 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR70383.1 - 0.00028 19.5 0.5 0.00028 19.5 0.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EMR70384.1 - 1.3e-30 106.5 31.0 1.3e-30 106.5 31.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PRA1 PF03208.19 EMR70385.1 - 1.7e-36 125.0 1.5 2.1e-36 124.7 1.5 1.1 1 0 0 1 1 1 1 PRA1 family protein Promethin PF16015.5 EMR70385.1 - 0.11 12.4 5.8 0.18 11.8 5.8 1.3 1 0 0 1 1 1 0 Promethin Ilm1 PF10311.9 EMR70386.1 - 1.5e-51 174.3 0.8 1.8e-51 174.1 0.8 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 IF-2B PF01008.17 EMR70387.1 - 9.8e-68 228.4 0.0 1.2e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family TRAPPC10 PF12584.8 EMR70388.1 - 8.3e-21 74.3 0.0 3.5e-11 43.1 0.0 3.1 3 0 0 3 3 3 2 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 EMR70388.1 - 0.017 14.7 0.3 0.029 14.0 0.3 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 Zn_clus PF00172.18 EMR70390.1 - 4.2e-05 23.6 7.5 6.8e-05 22.9 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.8 EMR70390.1 - 0.00047 20.1 5.5 0.00047 20.1 5.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) SSP160 PF06933.11 EMR70390.1 - 0.0039 15.5 10.1 0.0049 15.1 10.1 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.11 EMR70390.1 - 0.004 15.3 1.8 0.0065 14.6 1.8 1.3 1 1 0 1 1 1 1 Sporozoite P67 surface antigen zf_Rg PF17915.1 EMR70390.1 - 0.016 14.6 4.8 0.028 13.8 4.8 1.3 1 0 0 1 1 1 0 Reverse gyrase zinc finger DUF4778 PF16008.5 EMR70390.1 - 0.041 14.0 1.9 0.056 13.5 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Menin PF05053.13 EMR70390.1 - 0.18 10.2 9.4 0.2 10.0 9.4 1.1 1 0 0 1 1 1 0 Menin Dicty_REP PF05086.12 EMR70390.1 - 0.73 7.7 5.8 1.2 7.0 5.8 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CPSF100_C PF13299.6 EMR70390.1 - 1.1 9.4 7.1 0.46 10.7 4.7 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EMR70390.1 - 3.5 6.3 7.6 4.5 5.9 7.6 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EMR70390.1 - 3.8 6.4 6.9 5 6.0 6.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 BSP_II PF05432.11 EMR70390.1 - 4.6 6.9 15.1 8.9 5.9 15.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FXR_C1 PF16096.5 EMR70390.1 - 7.4 6.9 9.5 0.15 12.3 1.6 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 M20_dimer PF07687.14 EMR70391.1 - 3.2e-18 65.7 0.1 6.3e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EMR70391.1 - 2.2e-15 56.9 1.7 1.1e-14 54.7 1.7 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EMR70391.1 - 0.0088 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PITH PF06201.13 EMR70392.1 - 2.5e-39 134.9 0.1 3.5e-39 134.5 0.1 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EMR70392.1 - 7.5e-23 80.5 0.0 1.3e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMR70392.1 - 9.7e-07 29.2 0.0 2.8e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMR70392.1 - 0.00046 20.5 0.0 0.023 15.0 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 EMR70392.1 - 0.0083 15.8 0.4 0.56 9.9 0.0 2.9 2 1 1 3 3 3 1 Redoxin Thioredoxin_9 PF14595.6 EMR70392.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 EMR70392.1 - 0.15 11.4 0.0 0.74 9.1 0.0 1.9 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EMR70392.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family Tannase PF07519.11 EMR70393.1 - 2.2e-74 251.1 7.0 5.9e-73 246.4 7.0 2.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase PAN_4 PF14295.6 EMR70394.1 - 5.9e-05 22.9 1.1 9.5e-05 22.2 1.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 EMR70394.1 - 0.00057 19.7 0.9 0.00085 19.1 0.9 1.3 1 0 0 1 1 1 1 PAN-like domain PAN_1 PF00024.26 EMR70394.1 - 0.0012 18.7 0.9 0.0017 18.3 0.9 1.3 1 0 0 1 1 1 1 PAN domain DnaJ PF00226.31 EMR70395.1 - 2.6e-19 69.1 0.8 4e-19 68.5 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EMR70395.1 - 0.0039 17.5 1.1 0.0061 16.8 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 EMR70395.1 - 0.026 14.6 4.6 0.061 13.4 4.6 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide SRR PF07709.11 EMR70395.1 - 0.21 12.1 0.4 28 5.7 0.1 2.9 2 0 0 2 2 2 0 Seven Residue Repeat Spt20 PF12090.8 EMR70395.1 - 0.68 9.5 5.2 0.99 9.0 5.2 1.2 1 0 0 1 1 1 0 Spt20 family Patatin PF01734.22 EMR70396.1 - 0.072 13.2 0.0 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 Patatin-like phospholipase Prenyltrans PF00432.21 EMR70398.1 - 5.7e-40 134.7 4.1 4.2e-09 36.0 0.1 6.3 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EMR70398.1 - 0.15 11.1 0.0 0.67 9.0 0.0 2.0 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain Hydantoinase_B PF02538.14 EMR70399.1 - 4.4e-114 381.7 0.0 2.3e-64 217.7 0.0 2.3 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMR70399.1 - 1.8e-87 293.3 2.0 7.6e-87 291.2 0.2 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMR70399.1 - 3.4e-49 167.0 1.5 7.8e-47 159.3 0.1 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EMR70399.1 - 0.00023 19.9 2.0 0.27 9.8 0.2 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 EMR70399.1 - 0.2 11.1 1.4 1.6 8.2 0.2 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DIOX_N PF14226.6 EMR70400.1 - 9.2e-29 100.6 0.1 1.4e-28 100.0 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR70400.1 - 4.9e-20 71.9 0.0 9.9e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaI_N PF07319.11 EMR70400.1 - 0.043 14.5 0.0 0.088 13.5 0.0 1.4 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus MFS_1 PF07690.16 EMR70401.1 - 2.6e-34 118.7 27.6 2.6e-34 118.7 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMR70401.1 - 2.6e-06 27.0 0.5 2.6e-06 27.0 0.5 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB HpcH_HpaI PF03328.14 EMR70402.1 - 5.3e-29 100.9 0.0 8e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 EMR70402.1 - 0.00061 19.0 1.1 0.0069 15.5 0.5 2.7 3 1 0 3 3 3 1 PEP-utilising enzyme, TIM barrel domain 2-Hacid_dh_C PF02826.19 EMR70403.1 - 6.4e-45 152.7 0.0 7.9e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EMR70403.1 - 0.0012 19.0 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EMR70403.1 - 0.0076 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EMR70403.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Amidase PF01425.21 EMR70404.1 - 1.3e-14 54.0 0.0 1.2e-13 50.9 0.0 2.2 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 EMR70405.1 - 2.4e-31 108.9 25.7 4.6e-31 108.0 25.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M14 PF00246.24 EMR70406.1 - 2.4e-81 273.7 0.0 2.8e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Hydrolase_4 PF12146.8 EMR70407.1 - 1e-07 31.5 0.0 4.2e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR70407.1 - 4e-07 30.9 0.9 6.2e-07 30.2 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 EMR70407.1 - 9.5e-06 25.1 0.1 0.039 13.3 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase AAA PF00004.29 EMR70408.1 - 8.3e-91 301.3 0.0 9.2e-47 158.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMR70408.1 - 6.1e-14 52.1 0.0 4.7e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EMR70408.1 - 7.9e-14 51.2 7.0 1.3e-06 28.0 0.0 2.9 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 EMR70408.1 - 7.8e-12 45.9 2.1 0.0016 18.9 0.0 4.5 3 2 2 5 5 5 2 AAA ATPase domain AAA_33 PF13671.6 EMR70408.1 - 1.4e-11 44.8 0.0 1.8e-05 25.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EMR70408.1 - 3.7e-11 43.5 0.5 0.00094 19.5 0.1 4.2 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.14 EMR70408.1 - 2.9e-10 40.5 0.0 0.00065 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EMR70408.1 - 3e-10 40.2 0.2 0.00036 20.5 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EMR70408.1 - 1.9e-09 37.4 1.8 0.041 13.5 0.1 4.3 4 0 0 4 4 4 3 AAA domain AAA_14 PF13173.6 EMR70408.1 - 4.4e-09 36.5 0.0 0.00033 20.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EMR70408.1 - 3e-08 34.0 0.1 0.0037 17.6 0.0 3.1 3 1 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.17 EMR70408.1 - 3.8e-08 33.3 0.0 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 EMR70408.1 - 4.6e-08 33.5 0.0 0.0015 18.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EMR70408.1 - 6e-08 32.3 0.3 0.0057 16.1 0.2 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EMR70408.1 - 1.2e-07 31.3 0.7 0.0074 15.5 0.1 3.3 3 1 1 4 4 4 2 TIP49 P-loop domain AAA_18 PF13238.6 EMR70408.1 - 1.8e-07 31.8 0.0 0.0082 16.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 EMR70408.1 - 2.2e-07 30.9 0.0 0.0071 16.3 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 EMR70408.1 - 2.3e-07 31.1 0.0 0.00051 20.2 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase-like family NACHT PF05729.12 EMR70408.1 - 5.1e-07 29.7 0.3 0.006 16.5 0.0 3.2 3 1 1 4 4 3 2 NACHT domain Rad17 PF03215.15 EMR70408.1 - 1.6e-06 28.2 0.0 0.0082 16.1 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain ABC_tran PF00005.27 EMR70408.1 - 2.2e-06 28.2 0.0 0.13 12.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_7 PF12775.7 EMR70408.1 - 8.4e-06 25.4 0.0 0.065 12.7 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 EMR70408.1 - 1.3e-05 24.6 0.2 0.07 12.4 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin AAA_3 PF07726.11 EMR70408.1 - 1.8e-05 24.6 0.0 0.051 13.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EMR70408.1 - 2.3e-05 23.7 0.0 0.048 12.8 0.0 3.4 2 2 1 3 3 3 1 Protein of unknown function (DUF815) ATPase PF06745.13 EMR70408.1 - 2.5e-05 23.7 0.1 0.64 9.3 0.0 3.2 3 0 0 3 3 3 2 KaiC Sigma54_activat PF00158.26 EMR70408.1 - 9.3e-05 22.2 0.0 0.16 11.7 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 EMR70408.1 - 0.00013 22.4 1.2 0.22 12.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain NB-ARC PF00931.22 EMR70408.1 - 0.00015 21.1 0.1 0.73 9.0 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain AAA_11 PF13086.6 EMR70408.1 - 0.00015 21.7 0.4 0.74 9.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EMR70408.1 - 0.00016 21.5 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EMR70408.1 - 0.00028 20.9 0.0 1.3 8.9 0.0 3.4 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EMR70408.1 - 0.0005 20.2 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 EMR70408.1 - 0.0006 19.6 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EMR70408.1 - 0.00064 19.2 0.2 1.1 8.7 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.17 EMR70408.1 - 0.0012 18.0 0.1 1.5 7.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 TniB PF05621.11 EMR70408.1 - 0.0013 18.2 0.1 9.1 5.6 0.0 4.1 4 1 1 5 5 4 0 Bacterial TniB protein SKI PF01202.22 EMR70408.1 - 0.0037 17.4 0.5 4.2 7.5 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase AAA_19 PF13245.6 EMR70408.1 - 0.004 17.5 0.2 1.6 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EMR70408.1 - 0.0046 16.6 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 EMR70408.1 - 0.0068 16.3 0.2 3.6 7.5 0.0 3.1 2 1 1 3 3 3 0 NTPase SRPRB PF09439.10 EMR70408.1 - 0.011 15.2 0.1 3.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AFG1_ATPase PF03969.16 EMR70408.1 - 0.011 14.7 0.0 2.2 7.1 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase Cytidylate_kin PF02224.18 EMR70408.1 - 0.012 15.3 0.1 1.7 8.3 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase Bac_DnaA PF00308.18 EMR70408.1 - 0.018 14.9 0.0 4.4 7.1 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein DUF2075 PF09848.9 EMR70408.1 - 0.021 14.1 0.0 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.9 EMR70408.1 - 0.023 14.4 0.0 9.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Guanylate_kin PF00625.21 EMR70408.1 - 0.027 14.2 0.8 22 4.7 0.0 4.4 3 2 2 5 5 5 0 Guanylate kinase ResIII PF04851.15 EMR70408.1 - 0.028 14.4 0.0 8.4 6.4 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Hydin_ADK PF17213.3 EMR70408.1 - 0.032 14.5 0.1 0.51 10.6 0.0 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_30 PF13604.6 EMR70408.1 - 0.033 13.9 0.1 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 EMR70408.1 - 0.055 12.6 0.0 0.55 9.3 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain DAP3 PF10236.9 EMR70408.1 - 0.086 12.0 0.0 25 3.9 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 CPT PF07931.12 EMR70408.1 - 0.11 12.4 0.7 3.2 7.6 0.0 2.8 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein Cytochrom_C PF00034.21 EMR70409.1 - 7.4e-11 43.0 0.0 9.9e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EMR70409.1 - 2.2e-08 34.3 0.7 7.5e-08 32.6 0.7 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EMR70409.1 - 0.0019 17.9 0.1 0.031 14.0 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Myb_DNA-binding PF00249.31 EMR70411.1 - 0.0081 16.3 0.0 0.023 14.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HAD_2 PF13419.6 EMR70413.1 - 0.00048 20.3 0.0 0.00084 19.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Peptidase_A4 PF01828.17 EMR70414.1 - 3.5e-86 288.0 17.7 4.8e-86 287.6 17.7 1.2 1 0 0 1 1 1 1 Peptidase A4 family DUF917 PF06032.12 EMR70415.1 - 1.1e-123 412.5 0.4 2.1e-123 411.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 EMR70415.1 - 2.3e-33 115.4 0.3 1.5e-30 106.2 0.0 2.9 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EMR70415.1 - 2.7e-33 115.5 3.8 1.7e-29 103.0 0.1 3.5 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EMR70415.1 - 1.5e-06 27.9 7.4 0.00044 19.8 0.1 3.6 5 0 0 5 5 5 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 EMR70415.1 - 0.00059 18.5 1.6 0.0069 15.0 0.0 2.8 3 0 0 3 3 3 1 MutL protein ROK PF00480.20 EMR70415.1 - 0.002 17.7 0.0 0.0074 15.8 0.0 2.0 1 0 0 1 1 1 1 ROK family StbA PF06406.11 EMR70415.1 - 0.024 13.9 0.1 1.8 7.8 0.0 2.5 2 1 0 2 2 2 0 StbA protein CM_1 PF07736.11 EMR70415.1 - 0.052 13.9 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 Chorismate mutase type I FtsA PF14450.6 EMR70415.1 - 0.22 12.0 1.1 14 6.1 0.1 3.5 3 0 0 3 3 3 0 Cell division protein FtsA Raco_middle PF17651.1 EMR70415.1 - 2.7 7.7 4.5 2.3 7.9 0.1 3.0 4 0 0 4 4 4 0 RACo middle region p450 PF00067.22 EMR70416.1 - 2.8e-25 89.0 0.0 3.6e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EMR70417.1 - 2e-20 73.0 0.4 4.3e-20 71.9 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR70417.1 - 0.0012 18.9 0.1 0.0028 17.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like NAD_binding_10 PF13460.6 EMR70418.1 - 1.9e-07 31.1 0.0 2.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMR70418.1 - 2.7e-06 27.7 0.1 5.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EMR70418.1 - 3.1e-05 23.1 0.0 8.3e-05 21.7 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EMR70418.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR70418.1 - 0.00032 20.2 0.1 0.028 13.9 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EMR70418.1 - 0.0015 19.0 0.0 0.0059 17.0 0.0 1.9 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EMR70418.1 - 0.0039 16.4 0.2 0.43 9.7 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein DUF2500 PF10694.9 EMR70419.1 - 0.076 13.5 0.2 0.21 12.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Pannexin_like PF12534.8 EMR70419.1 - 0.27 10.3 7.1 2.4 7.2 0.5 2.2 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Pro-kuma_activ PF09286.11 EMR70420.1 - 5.7e-44 149.9 0.1 2.1e-42 144.8 0.2 2.3 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMR70420.1 - 3.7e-06 26.4 0.3 7.2e-06 25.5 0.3 1.5 1 0 0 1 1 1 1 Subtilase family Transp_cyt_pur PF02133.15 EMR70421.1 - 1.8e-80 270.9 39.1 2.9e-80 270.2 39.1 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RlmM_FDX PF18125.1 EMR70421.1 - 0.046 14.2 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 RlmM ferredoxin-like domain Baculo_p74 PF04583.12 EMR70421.1 - 0.17 11.4 0.2 0.38 10.2 0.2 1.5 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Man-6-P_recep PF02157.15 EMR70422.1 - 5.2e-18 65.0 0.0 1.2e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EMR70422.1 - 4.1e-15 56.3 0.0 1.4e-14 54.7 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 EMR70422.1 - 3e-07 30.6 0.2 0.00027 21.0 0.2 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF2722 PF10846.8 EMR70422.1 - 0.06 12.3 1.1 0.084 11.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 EMR70422.1 - 0.1 10.8 9.6 0.36 9.0 7.1 2.1 2 0 0 2 2 2 0 Nop14-like family HRG PF16954.5 EMR70422.1 - 0.11 12.9 1.9 0.22 12.0 1.3 1.8 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene CDC45 PF02724.14 EMR70422.1 - 1.1 7.5 7.6 1.4 7.1 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 EMR70422.1 - 1.3 8.1 6.0 2.5 7.2 6.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 EMR70422.1 - 2.6 7.3 10.0 4.3 6.6 10.0 1.3 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 EMR70422.1 - 2.9 7.4 10.6 4.2 6.9 10.6 1.2 1 0 0 1 1 1 0 PPP4R2 BTV_NS2 PF04514.12 EMR70422.1 - 4.8 5.9 7.1 7.6 5.3 7.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 p450 PF00067.22 EMR70423.1 - 2.2e-44 152.0 0.0 2.7e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EMR70424.1 - 6.8e-31 107.5 0.0 9.2e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1097 PF06496.11 EMR70424.1 - 0.13 12.4 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) p450 PF00067.22 EMR70425.1 - 3.4e-42 144.8 0.0 1e-41 143.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EMR70426.1 - 3.5e-17 62.5 0.0 3.9e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70426.1 - 6.2e-13 48.9 0.1 7.4e-13 48.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70426.1 - 3e-08 33.8 0.0 3.3e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR70426.1 - 0.00037 19.7 0.1 0.00045 19.5 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMR70426.1 - 0.0011 18.5 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 EMR70426.1 - 0.046 13.3 0.2 0.064 12.8 0.2 1.3 1 0 0 1 1 1 0 SLOG cluster4 family YjcB PF15940.5 EMR70426.1 - 0.079 13.1 0.2 0.37 11.0 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function ThiF PF00899.21 EMR70426.1 - 0.44 9.9 1.7 0.66 9.3 1.7 1.2 1 0 0 1 1 1 0 ThiF family adh_short PF00106.25 EMR70427.1 - 1.2e-20 73.8 0.5 5.2e-18 65.2 1.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70427.1 - 5.6e-11 42.4 0.5 9.5e-09 35.1 0.5 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70427.1 - 6.2e-11 42.5 0.6 9.5e-11 41.9 0.6 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 EMR70427.1 - 0.084 13.5 0.3 0.16 12.6 0.3 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EMR70428.1 - 2.4e-13 50.1 0.1 7e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMR70428.1 - 4e-13 49.5 0.0 5.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EMR70428.1 - 8.6e-07 28.8 0.4 1.9e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMR70428.1 - 1.7e-05 24.2 0.1 2.9e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EMR70428.1 - 0.00013 21.5 0.2 0.00071 19.0 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR70428.1 - 0.00037 19.3 0.1 0.00053 18.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EMR70428.1 - 0.00053 19.2 0.1 0.00097 18.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR70428.1 - 0.00079 18.8 0.2 0.0018 17.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR70428.1 - 0.0026 17.8 0.2 0.046 13.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMR70428.1 - 0.0067 15.7 0.1 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EMR70428.1 - 0.016 14.9 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MCRA PF06100.11 EMR70428.1 - 0.018 13.8 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 MCRA family LDcluster4 PF18306.1 EMR70428.1 - 0.028 14.0 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 SLOG cluster4 family GMC_oxred_N PF00732.19 EMR70428.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Lycopene_cycl PF05834.12 EMR70428.1 - 0.035 13.1 0.0 0.29 10.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 EMR70428.1 - 0.096 11.5 0.2 0.15 10.9 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 EMR70428.1 - 0.11 13.0 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMR70428.1 - 0.19 12.0 0.1 0.38 11.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ERG4_ERG24 PF01222.17 EMR70429.1 - 2.6e-169 563.5 3.1 3e-169 563.3 3.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EMR70429.1 - 0.0003 20.4 0.1 0.00083 18.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Glyco_hydro_16 PF00722.21 EMR70430.1 - 1.3e-16 60.6 0.7 2e-16 60.0 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 EMR70431.1 - 1.3e-41 142.0 0.3 1.8e-41 141.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 EMR70432.1 - 4.5e-52 176.9 2.0 4.5e-52 176.9 2.0 2.1 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMR70432.1 - 5.6e-06 26.3 0.1 3.6e-05 23.6 0.0 2.3 2 1 1 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EMR70432.1 - 0.0034 16.9 0.0 0.0076 15.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EMR70432.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Flavi_NS2A PF01005.19 EMR70432.1 - 0.032 14.4 0.2 0.07 13.3 0.2 1.5 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A Ribosomal_L3 PF00297.22 EMR70433.1 - 3.7e-183 608.6 10.3 4.2e-183 608.4 10.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Transferase PF02458.15 EMR70434.1 - 2.9e-07 29.5 0.0 3.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Transferase family FAD_binding_4 PF01565.23 EMR70435.1 - 7.5e-22 77.6 0.6 1.5e-21 76.6 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR70435.1 - 0.00011 22.3 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Caskin1-CID PF16600.5 EMR70436.1 - 5 7.8 7.4 12 6.6 7.4 1.6 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain LIP PF03583.14 EMR70437.1 - 5.2e-50 170.4 0.0 7e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase FAM199X PF15814.5 EMR70439.1 - 2.9 6.9 7.9 3.5 6.6 7.9 1.1 1 0 0 1 1 1 0 Protein family FAM199X Ribosomal_L34e PF01199.18 EMR70440.1 - 1.4e-43 147.1 1.6 1.8e-43 146.7 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 EMR70440.1 - 0.086 12.2 0.3 0.086 12.2 0.3 1.7 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 EMR70440.1 - 0.47 10.4 5.4 1.6 8.7 0.3 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.11 EMR70441.1 - 3e-235 780.4 7.9 3e-235 780.4 7.9 1.8 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EMR70441.1 - 1.3e-126 420.8 1.1 2.7e-126 419.8 1.1 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EMR70441.1 - 1.9e-84 281.4 2.2 1.3e-57 194.2 0.3 3.0 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EMR70441.1 - 2.9e-79 264.3 2.6 8.3e-79 262.8 2.6 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EMR70441.1 - 1.5e-71 238.7 0.1 3.3e-71 237.6 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EMR70441.1 - 9.8e-48 160.4 0.3 2.7e-47 159.0 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EMR70441.1 - 3.6e-43 146.4 0.0 1e-42 144.9 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain Hom_end_hint PF05203.16 EMR70441.1 - 2.2e-07 31.1 2.3 2.7e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Hom_end-associated Hint NCU-G1 PF15065.6 EMR70442.1 - 0.06 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Inhibitor_I78 PF11720.8 EMR70444.1 - 2.1e-14 53.3 0.0 2.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EMR70444.1 - 0.00016 22.3 0.2 0.00023 21.8 0.2 1.4 1 1 0 1 1 1 1 Potato inhibitor I family Pre-PUA PF17832.1 EMR70445.1 - 4.7e-24 84.9 0.1 6.5e-24 84.4 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EMR70445.1 - 5.6e-13 48.7 0.0 3.1e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 PUA domain DUF1947 PF09183.10 EMR70445.1 - 0.042 14.1 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) DUF4112 PF13430.6 EMR70446.1 - 1.1e-31 109.2 0.5 1.4e-31 108.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) WD40 PF00400.32 EMR70447.1 - 3.6e-12 46.6 2.6 2.5e-06 28.1 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR70447.1 - 0.00016 21.9 0.0 0.39 11.0 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Biotin_lipoyl PF00364.22 EMR70449.1 - 1.7e-19 69.4 0.6 2.9e-19 68.6 0.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EMR70449.1 - 6.1e-10 39.3 0.0 3.4e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EMR70449.1 - 6.2e-05 22.7 0.1 0.00078 19.2 0.0 2.6 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 EMR70449.1 - 0.04 14.6 0.2 0.58 10.9 0.0 2.6 1 1 1 2 2 2 0 HlyD family secretion protein Pep1_7 PF17232.2 EMR70449.1 - 4.9 7.7 9.0 21 5.7 7.1 2.3 2 0 0 2 2 2 0 Elicitor peptide 1-7 CTP_transf_like PF01467.26 EMR70450.1 - 9.9e-07 29.0 0.1 5.1e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like CoA_transf_3 PF02515.17 EMR70451.1 - 5e-36 124.6 0.4 2.5e-32 112.4 0.9 3.2 2 1 0 2 2 2 2 CoA-transferase family III Ribonuc_red_sm PF00268.21 EMR70452.1 - 1.7e-120 401.7 1.4 2.1e-120 401.4 1.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 EMR70453.1 - 4.7e-35 119.9 3.7 4.7e-35 119.9 3.7 2.0 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) DUF4799 PF16056.5 EMR70453.1 - 0.28 10.3 5.2 0.055 12.6 0.8 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4799) G-gamma PF00631.22 EMR70454.1 - 4.9e-25 87.3 0.0 6.4e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 GGL domain Fungal_trans PF04082.18 EMR70457.1 - 2.1e-24 86.0 0.1 3.6e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-HC5HC2H_2 PF13832.6 EMR70458.1 - 2.7e-33 114.4 5.7 2.7e-33 114.4 5.7 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 EMR70458.1 - 2.6e-29 102.6 1.2 4.7e-29 101.8 0.0 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 EMR70458.1 - 1.8e-25 89.0 5.1 1.8e-25 89.0 5.1 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EMR70458.1 - 3.4e-14 52.1 1.9 3.4e-14 52.1 1.9 2.0 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EMR70458.1 - 6e-09 35.7 24.6 1.3e-08 34.6 9.5 2.7 2 0 0 2 2 2 2 PHD-finger DUF3736 PF12540.8 EMR70458.1 - 0.21 11.7 3.5 0.25 11.5 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) zf-PHD-like PF15446.6 EMR70458.1 - 3 7.4 13.0 0.035 13.7 2.6 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Glyco_hydro_64 PF16483.5 EMR70460.1 - 2e-124 415.6 0.0 2.3e-124 415.4 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase SGL PF08450.12 EMR70461.1 - 7.1e-62 209.2 0.0 1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EMR70461.1 - 0.00011 22.1 0.1 0.00067 19.5 0.1 2.3 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Arylesterase PF01731.20 EMR70461.1 - 0.056 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Arylesterase Phytase-like PF13449.6 EMR70461.1 - 0.069 13.1 0.1 0.28 11.1 0.0 1.8 2 1 0 2 2 2 0 Esterase-like activity of phytase Reg_prop PF07494.11 EMR70461.1 - 0.11 12.7 0.2 5.9 7.5 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller Glyco_hydro_16 PF00722.21 EMR70463.1 - 2.4e-09 36.9 0.1 3.4e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1810 PF08837.11 EMR70464.1 - 7.7e-49 165.0 0.1 9.3e-49 164.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1810) PLDc_2 PF13091.6 EMR70464.1 - 0.11 12.4 0.0 0.7 9.8 0.0 2.0 1 1 0 1 1 1 0 PLD-like domain TINF2_N PF14973.6 EMR70464.1 - 0.16 12.3 0.1 0.23 11.8 0.1 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus TPR_2 PF07719.17 EMR70465.1 - 5.1e-08 32.4 11.2 0.025 14.7 1.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMR70465.1 - 1.4e-07 31.7 22.5 0.012 16.4 1.1 8.9 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMR70465.1 - 1.4e-06 28.3 0.5 0.02 15.3 0.2 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR70465.1 - 2.4e-06 28.0 4.4 0.023 15.2 0.3 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMR70465.1 - 2.4e-05 24.2 5.1 0.013 15.7 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR70465.1 - 0.00057 20.5 6.0 11 6.8 1.3 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR70465.1 - 0.0046 16.7 8.1 0.11 12.4 0.3 6.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMR70465.1 - 0.0076 16.5 14.1 11 6.4 0.3 7.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 EMR70465.1 - 0.046 13.9 0.4 6 7.1 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PUL PF08324.11 EMR70465.1 - 0.075 12.3 0.2 1.2 8.3 0.0 2.7 2 1 1 3 3 3 0 PUL domain TPR_6 PF13174.6 EMR70465.1 - 0.13 13.0 2.3 0.89 10.3 0.7 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMR70465.1 - 8.8 6.6 8.5 8.2 6.7 0.2 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat FAM184 PF15665.5 EMR70466.1 - 0.047 13.5 5.8 0.069 12.9 5.8 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B PilJ PF13675.6 EMR70466.1 - 0.21 11.6 1.6 0.45 10.6 1.3 1.8 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Apolipoprotein PF01442.18 EMR70466.1 - 0.47 10.3 11.3 0.93 9.3 11.3 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EMR70466.1 - 4.4 8.0 7.3 1 10.0 0.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) WW PF00397.26 EMR70467.1 - 7e-08 32.4 6.1 7e-08 32.4 6.1 2.0 2 0 0 2 2 2 1 WW domain WRW PF10206.9 EMR70467.1 - 0.0023 18.3 0.6 0.0057 17.0 0.6 1.6 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Glyco_transf_90 PF05686.12 EMR70468.1 - 6e-15 55.1 7.6 2e-12 46.8 4.4 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 PCI PF01399.27 EMR70469.1 - 2.9e-08 34.2 0.3 6.5e-07 29.8 0.0 2.8 2 0 0 2 2 2 1 PCI domain DPBB_1 PF03330.18 EMR70471.1 - 1.3e-07 31.8 0.0 2.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EMR70471.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Barwin family Pex14_N PF04695.13 EMR70471.1 - 0.19 12.4 5.0 0.31 11.7 5.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S49 PF01343.18 EMR70472.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 NPCC PF08058.11 EMR70472.1 - 0.17 11.9 0.1 0.84 9.7 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore complex component RTT107_BRCT_5 PF16770.5 EMR70473.1 - 7.8e-35 118.8 1.0 5.5e-32 109.6 0.0 4.3 5 0 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EMR70473.1 - 1.5e-28 98.5 1.7 8.6e-19 67.3 0.1 4.7 5 0 0 5 5 5 3 twin BRCT domain BRCT_2 PF16589.5 EMR70473.1 - 2e-27 95.4 1.2 0.00017 21.9 0.1 6.2 5 1 1 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EMR70473.1 - 1.2e-22 80.1 0.3 3.4e-06 27.3 0.0 5.7 6 1 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EMR70473.1 - 2.7e-12 46.8 0.7 0.23 11.8 0.1 5.0 5 0 0 5 5 5 4 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EMR70473.1 - 2.2e-06 27.7 0.2 1.1 9.4 0.0 5.0 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain Skp1 PF01466.19 EMR70474.1 - 2.8e-16 59.3 0.0 2.8e-16 59.3 0.0 2.2 3 0 0 3 3 3 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EMR70474.1 - 6.4e-13 48.7 0.0 1.6e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Glyco_hydro_28 PF00295.17 EMR70475.1 - 6.6e-40 137.1 4.0 9.7e-40 136.6 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 PhoD PF09423.10 EMR70475.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase FAR1 PF03101.15 EMR70476.1 - 1.1e-07 32.5 0.1 1.1e-07 32.5 0.1 1.8 2 1 0 2 2 2 1 FAR1 DNA-binding domain adh_short PF00106.25 EMR70477.1 - 7.9e-27 94.0 0.0 3.6e-13 49.4 0.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70477.1 - 2.5e-21 76.3 0.1 3e-10 40.1 0.1 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70477.1 - 0.12 12.3 2.3 14 5.6 0.2 3.2 3 1 0 3 3 3 0 KR domain DHBP_synthase PF00926.19 EMR70477.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase 2OG-FeII_Oxy PF03171.20 EMR70478.1 - 4e-06 27.2 0.0 6.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAS PF00989.25 EMR70479.1 - 0.0029 17.6 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 PAS fold CDC45 PF02724.14 EMR70479.1 - 1.2 7.3 7.2 1.6 6.9 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pyridox_ox_2 PF12900.7 EMR70480.1 - 1.5e-32 112.5 0.0 2.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GATase_6 PF13522.6 EMR70480.1 - 7.5e-09 35.9 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EMR70480.1 - 4.7e-05 22.4 0.0 8.9e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Zds_C PF08632.10 EMR70481.1 - 1.7e-29 101.3 1.2 3.1e-29 100.5 1.2 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Bac_rhamnosid_C PF17390.2 EMR70482.1 - 9.1e-05 22.2 0.0 0.00044 20.0 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain adh_short_C2 PF13561.6 EMR70483.1 - 1.7e-45 155.4 3.0 5e-45 153.9 3.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR70483.1 - 9.9e-45 152.4 0.9 3.4e-44 150.6 0.9 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR70483.1 - 8.3e-07 29.1 0.2 1.8e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.6 EMR70483.1 - 0.00044 20.8 0.3 0.0011 19.5 0.3 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain zf-RING_2 PF13639.6 EMR70484.1 - 1.3e-11 44.6 2.1 2e-11 44.0 2.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EMR70484.1 - 3.9e-07 30.3 3.0 1.2e-06 28.7 3.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EMR70484.1 - 7e-06 26.0 1.6 7e-06 26.0 1.6 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMR70484.1 - 1e-05 25.4 1.4 1.8e-05 24.7 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EMR70484.1 - 1.1e-05 25.2 2.7 2.2e-05 24.2 2.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR70484.1 - 7.1e-05 22.6 1.9 0.0002 21.2 1.9 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMR70484.1 - 0.00037 20.3 2.3 0.13 12.2 0.4 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EMR70484.1 - 0.00038 20.3 0.9 0.00064 19.5 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EMR70484.1 - 0.0043 16.9 2.2 0.23 11.3 0.1 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Di19 PF05605.12 EMR70484.1 - 0.0049 17.1 0.7 3 8.2 0.1 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.6 EMR70484.1 - 0.034 14.3 3.8 0.071 13.3 3.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMR70484.1 - 0.047 13.7 1.3 0.11 12.4 1.4 1.6 1 1 0 1 1 1 0 zinc-RING finger domain UBZ_FAAP20 PF15750.5 EMR70484.1 - 0.063 13.2 0.5 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-RING_11 PF17123.5 EMR70484.1 - 0.078 12.7 0.1 0.078 12.7 0.1 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 EMR70484.1 - 0.089 12.6 5.9 1.5 8.7 6.0 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 EMR70484.1 - 0.1 12.7 2.6 1.1 9.4 0.5 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger Tmpp129 PF10272.9 EMR70484.1 - 0.13 11.6 0.2 0.21 10.9 0.2 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor FANCL_C PF11793.8 EMR70484.1 - 0.15 12.3 1.2 4.2 7.6 1.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Zn-C2H2_12 PF18112.1 EMR70484.1 - 0.82 10.2 4.2 11 6.6 0.2 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_5 PF17121.5 EMR70484.1 - 2 8.4 5.0 13 5.7 5.2 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ndc80_HEC PF03801.13 EMR70485.1 - 6.2e-61 204.5 0.1 1.8e-60 203.0 0.1 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.11 EMR70485.1 - 0.011 14.7 49.5 0.0067 15.3 15.7 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF16 PF01519.16 EMR70485.1 - 0.021 15.3 8.6 0.021 15.3 8.6 3.7 3 1 1 4 4 4 0 Protein of unknown function DUF16 DUF2935 PF11155.8 EMR70485.1 - 0.065 13.6 7.4 0.1 12.9 0.1 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) Filament PF00038.21 EMR70485.1 - 0.067 12.8 49.6 0.44 10.1 0.7 3.4 3 1 1 4 4 4 0 Intermediate filament protein Spiralin PF05215.13 EMR70485.1 - 0.22 10.8 4.3 0.09 12.1 1.2 1.9 2 0 0 2 2 2 0 Spiralin TPR_MLP1_2 PF07926.12 EMR70485.1 - 1.1 9.3 47.1 0.36 10.9 15.5 4.1 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein THDPS_N_2 PF14805.6 EMR70485.1 - 1.8 8.9 7.6 0.15 12.3 0.5 2.9 3 0 0 3 3 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Atg14 PF10186.9 EMR70485.1 - 1.9 7.5 29.2 3.4 6.6 13.1 2.6 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4391 PF14335.6 EMR70485.1 - 2.9 7.5 18.8 0.016 14.9 4.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4391) ATG16 PF08614.11 EMR70485.1 - 3.4 7.8 41.2 0.11 12.7 14.5 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Lipoprotein_10 PF03202.13 EMR70485.1 - 3.9 7.9 6.7 26 5.3 0.4 2.9 3 0 0 3 3 3 0 Putative mycoplasma lipoprotein, C-terminal region DUF4407 PF14362.6 EMR70485.1 - 4.1 6.7 34.7 0.74 9.1 9.6 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EMR70485.1 - 5.4 7.6 14.6 8.1 7.0 2.6 4.2 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.16 EMR70485.1 - 6 7.1 39.6 0.077 13.2 6.1 4.2 3 1 1 4 4 4 0 Flagellar FliJ protein DUF948 PF06103.11 EMR70485.1 - 8 6.8 13.9 2.4 8.4 0.9 4.4 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) CDV3 PF15359.6 EMR70486.1 - 0.013 16.0 0.0 0.013 16.0 0.0 1.7 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DSBA PF01323.20 EMR70486.1 - 0.17 11.7 0.0 8 6.2 0.0 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin PF00085.20 EMR70487.1 - 3.1e-23 81.7 0.0 3.6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMR70487.1 - 2.5e-06 27.9 0.4 3.6e-05 24.2 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMR70487.1 - 5.1e-06 26.7 0.0 1.5e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EMR70487.1 - 1e-05 25.0 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EMR70487.1 - 0.00026 20.9 0.1 0.0006 19.7 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMR70487.1 - 0.0012 18.6 0.2 0.13 12.0 0.0 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 EMR70487.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 EMR70487.1 - 0.049 13.5 0.1 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 EMR70487.1 - 0.073 13.0 0.0 0.14 12.2 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 EMR70487.1 - 0.094 12.9 0.1 0.22 11.7 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like DIM1 PF02966.16 EMR70487.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Cyt-b5 PF00173.28 EMR70489.1 - 3.1e-22 78.5 0.1 4.8e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF347 PF03988.12 EMR70489.1 - 0.071 13.3 0.1 0.096 12.9 0.1 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) U62_UL91 PF17442.2 EMR70489.1 - 0.078 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins FAD_binding_3 PF01494.19 EMR70490.1 - 3.1e-18 66.2 1.3 2.1e-08 33.8 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMR70490.1 - 4.7e-07 29.9 0.5 1.4e-06 28.5 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR70490.1 - 5.5e-06 25.7 1.8 2e-05 23.9 2.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EMR70490.1 - 2.8e-05 23.9 3.1 5e-05 23.1 2.0 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR70490.1 - 8.6e-05 21.9 1.7 0.0017 17.6 0.9 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR70490.1 - 0.00019 20.9 0.9 0.00029 20.3 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR70490.1 - 0.0002 20.2 0.0 0.00027 19.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EMR70490.1 - 0.00025 20.2 1.2 0.0027 16.8 1.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 EMR70490.1 - 0.00077 18.6 0.2 0.0012 18.0 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EMR70490.1 - 0.0071 15.7 0.2 0.023 14.0 0.1 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.16 EMR70490.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EMR70490.1 - 0.016 15.7 1.9 0.055 14.0 1.3 2.2 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR70490.1 - 0.027 13.3 0.6 0.2 10.4 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EMR70490.1 - 0.033 13.5 0.6 0.052 12.8 0.6 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMR70490.1 - 0.039 13.2 1.0 0.073 12.4 1.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EMR70490.1 - 0.039 13.2 0.3 0.059 12.6 0.3 1.2 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EMR70490.1 - 0.18 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Esterase_phd PF10503.9 EMR70491.1 - 4.8e-17 62.2 0.1 7.5e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMR70491.1 - 1.6e-09 37.5 0.1 3.3e-09 36.5 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EMR70491.1 - 0.00025 20.8 0.4 0.00043 20.0 0.3 1.4 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.28 EMR70491.1 - 0.0015 17.5 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 EMR70491.1 - 0.004 16.8 0.1 0.011 15.4 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR70491.1 - 0.019 15.6 0.0 0.05 14.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Asparaginase PF00710.20 EMR70491.1 - 0.046 13.3 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Asparaginase, N-terminal Tannase PF07519.11 EMR70491.1 - 0.047 12.6 0.0 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Tannase and feruloyl esterase p450 PF00067.22 EMR70492.1 - 3.9e-47 161.1 0.0 4.3e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ESCRT-II PF05871.12 EMR70493.1 - 1.4e-54 184.2 0.0 2.3e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 ESCRT-II complex subunit DnaB_2 PF07261.11 EMR70493.1 - 0.16 11.7 0.0 17 5.2 0.0 2.7 3 0 0 3 3 3 0 Replication initiation and membrane attachment F-actin_cap_A PF01267.17 EMR70494.1 - 3.7e-94 315.1 0.0 4.8e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Transket_pyr PF02779.24 EMR70494.1 - 7e-43 146.4 0.0 1.2e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMR70494.1 - 1e-30 106.2 0.0 2.3e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EMR70494.1 - 0.0018 18.5 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II TFA2_Winged_2 PF18121.1 EMR70495.1 - 1.2e-19 69.8 0.0 2.2e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EMR70495.1 - 3.9e-11 43.1 0.1 4e-10 39.8 0.0 2.6 2 1 0 2 2 2 1 TFIIE beta subunit core domain DUF390 PF04094.14 EMR70495.1 - 4.3 5.5 15.2 0.55 8.5 11.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF390) Cellulase PF00150.18 EMR70496.1 - 9.6e-11 41.6 0.4 9.6e-11 41.6 0.4 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.6 EMR70496.1 - 0.0025 18.7 0.0 0.0058 17.5 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF5518 PF17647.1 EMR70496.1 - 0.042 14.0 2.8 0.072 13.2 2.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5518) SecG PF03840.14 EMR70496.1 - 0.07 13.2 0.4 0.14 12.3 0.4 1.4 1 0 0 1 1 1 0 Preprotein translocase SecG subunit DUF2433 PF10360.9 EMR70497.1 - 2.1e-48 163.5 0.0 3.2e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) ketoacyl-synt PF00109.26 EMR70498.1 - 7.3e-54 183.0 0.7 1.8e-33 116.2 0.0 2.9 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR70498.1 - 2.3e-37 127.6 0.1 6e-37 126.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 EMR70498.1 - 1.5e-27 95.3 0.0 5.7e-27 93.4 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 EMR70498.1 - 5.6e-21 75.4 0.0 1.1e-20 74.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EMR70498.1 - 2.9e-20 72.7 0.0 8e-20 71.3 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.25 EMR70498.1 - 2.2e-16 60.0 1.0 4.8e-16 58.9 1.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EMR70498.1 - 5.1e-16 59.2 0.0 1.7e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 EMR70498.1 - 2.6e-15 56.9 0.0 5.9e-12 45.9 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_23 PF13489.6 EMR70498.1 - 3e-12 46.7 0.0 4.5e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain SAT PF16073.5 EMR70498.1 - 4.5e-11 42.9 5.2 7.5e-09 35.7 0.0 4.4 4 1 0 4 4 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_25 PF13649.6 EMR70498.1 - 5.2e-10 39.9 0.0 3.4e-09 37.3 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EMR70498.1 - 5.7e-09 36.4 0.0 1.5e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 EMR70498.1 - 1.1e-07 32.4 0.0 4.3e-06 27.3 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.21 EMR70498.1 - 2.6e-06 27.0 0.0 0.00044 19.8 0.0 2.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_31 PF13847.6 EMR70498.1 - 3.4e-06 26.9 0.0 8.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.7 EMR70498.1 - 0.00034 21.3 3.9 0.00034 21.3 3.9 4.1 4 0 0 4 4 4 1 Alpha/beta hydrolase family Methyltransf_33 PF10017.9 EMR70498.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF938 PF06080.12 EMR70498.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) COesterase PF00135.28 EMR70498.1 - 0.065 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family Ubie_methyltran PF01209.18 EMR70498.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SRP-alpha_N PF04086.13 EMR70499.1 - 1.5 8.7 13.0 1.6 8.6 13.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.9 EMR70499.1 - 6.7 5.1 7.4 7.9 4.9 7.4 1.0 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_75 PF07335.11 EMR70500.1 - 1.8e-40 138.9 0.3 2.6e-40 138.4 0.3 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF3632 PF12311.8 EMR70500.1 - 6.7e-12 46.2 2.9 9.6e-12 45.7 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Abhydrolase_3 PF07859.13 EMR70501.1 - 2.7e-46 158.1 0.0 3.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR70501.1 - 2.2e-05 23.5 0.4 0.00016 20.7 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 EMR70501.1 - 0.094 12.2 0.8 0.41 10.1 0.8 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase DUF3025 PF11227.8 EMR70501.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) EXS PF03124.14 EMR70503.1 - 1.9e-41 142.5 5.3 2.5e-41 142.1 5.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EMR70503.1 - 1.9e-18 67.6 2.2 1.9e-18 67.6 2.2 2.3 2 0 0 2 2 2 1 SPX domain PPP4R2 PF09184.11 EMR70503.1 - 0.17 11.5 9.1 0.26 10.9 9.1 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 EMR70503.1 - 1 9.2 10.7 1.6 8.7 10.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 EMR70503.1 - 1.8 7.8 13.6 3 7.1 13.6 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EMR70503.1 - 4.7 5.3 14.9 6.3 4.9 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 EMR70503.1 - 5.3 6.8 9.2 2.4 7.9 5.7 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Cwf_Cwc_15 PF04889.12 EMR70503.1 - 9.4 5.9 25.3 18 5.0 25.3 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Yip1 PF04893.17 EMR70504.1 - 0.0076 16.0 0.7 1.7 8.4 0.0 2.1 2 0 0 2 2 2 2 Yip1 domain MFS_1 PF07690.16 EMR70505.1 - 7.4e-16 58.0 7.4 1.5e-13 50.4 2.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4017 PF13209.6 EMR70505.1 - 0.055 13.4 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) PLA2_B PF01735.18 EMR70506.1 - 1e-184 614.6 3.6 1.2e-184 614.4 3.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.30 EMR70507.1 - 1.6e-23 83.0 0.0 3.2e-11 43.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain UBA PF00627.31 EMR70508.1 - 0.0016 18.3 0.1 0.0054 16.6 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.31 EMR70508.1 - 0.026 14.6 0.1 0.076 13.1 0.1 1.7 1 0 0 1 1 1 0 DnaJ domain Methyltransf_31 PF13847.6 EMR70509.1 - 6e-06 26.1 0.0 7.1e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR70509.1 - 1.3e-05 25.8 0.1 2.4e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR70509.1 - 2.5e-05 24.8 0.0 4.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR70509.1 - 0.0054 16.6 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF1996 PF09362.10 EMR70510.1 - 1.3e-84 283.9 0.1 1.8e-84 283.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) APH PF01636.23 EMR70511.1 - 0.0017 18.3 0.0 0.06 13.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.11 EMR70511.1 - 0.0052 16.4 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) DNA_Packaging_2 PF11123.8 EMR70511.1 - 0.044 14.0 0.0 2 8.7 0.0 2.3 2 0 0 2 2 2 0 DNA packaging protein Kdo PF06293.14 EMR70511.1 - 0.063 12.6 0.1 0.093 12.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.24 EMR70512.1 - 4.6e-114 381.8 19.4 5.4e-114 381.5 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR70512.1 - 2.4e-19 69.5 35.6 3.2e-15 55.9 9.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_2 PF07719.17 EMR70514.1 - 0.0042 17.1 0.1 0.0087 16.1 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat PCI PF01399.27 EMR70514.1 - 0.0055 17.2 0.0 3.3 8.3 0.0 3.1 3 0 0 3 3 3 2 PCI domain UQ_con PF00179.26 EMR70515.1 - 6.9e-52 174.8 0.1 7.8e-52 174.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMR70515.1 - 0.00057 19.6 0.0 0.00064 19.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMR70515.1 - 0.061 13.6 0.0 0.081 13.2 0.0 1.4 1 1 0 1 1 1 0 RWD domain Mito_carr PF00153.27 EMR70516.1 - 0.08 12.9 0.2 8.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial carrier protein Thiolase_N PF00108.23 EMR70517.1 - 2.4e-85 286.0 0.4 4.7e-85 285.1 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMR70517.1 - 4e-38 129.8 0.7 4e-38 129.8 0.7 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMR70517.1 - 8.4e-05 22.3 2.4 0.00014 21.6 0.5 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Kinesin PF00225.23 EMR70518.1 - 5.1e-112 374.1 0.1 5.1e-112 374.1 0.1 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EMR70518.1 - 1.6e-25 89.8 0.0 6.9e-25 87.7 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding DUF4404 PF14357.6 EMR70518.1 - 0.06 14.0 0.2 0.06 14.0 0.2 6.6 2 2 4 7 7 7 0 Domain of unknown function (DUF4404) DUF1398 PF07166.11 EMR70518.1 - 0.1 12.7 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) CALCOCO1 PF07888.11 EMR70518.1 - 0.17 10.7 53.4 0.12 11.3 30.0 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.6 EMR70518.1 - 2.2 7.6 63.2 0.07 12.5 12.2 5.0 4 1 1 5 5 5 0 Growth-arrest specific micro-tubule binding AA_permease PF00324.21 EMR70520.1 - 6e-114 381.3 37.1 7.2e-114 381.0 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR70520.1 - 2.2e-19 69.6 40.4 2.8e-19 69.2 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.11 EMR70520.1 - 0.58 10.2 4.9 0.42 10.6 2.3 2.0 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 S_4TM PF18159.1 EMR70520.1 - 3.3 6.9 0.0 3.3 6.9 0.0 2.9 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain Suc_Fer-like PF06999.12 EMR70521.1 - 3.4e-56 190.2 0.0 5e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.24 EMR70521.1 - 1.5e-05 25.2 0.1 8.5e-05 22.8 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EMR70521.1 - 0.00053 20.6 0.1 0.014 16.0 0.0 2.8 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Ysc84 PF04366.12 EMR70522.1 - 1.7e-43 147.4 0.1 2.8e-43 146.7 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Inj_translocase PF16928.5 EMR70522.1 - 5.7 6.3 7.0 15 5.0 0.5 2.2 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome CoA_binding PF02629.19 EMR70523.1 - 4.6e-29 101.0 3.6 5.2e-29 100.8 0.8 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EMR70523.1 - 1.1e-23 83.7 0.2 1.8e-23 83.0 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EMR70523.1 - 4.6e-09 36.2 0.0 7.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EMR70523.1 - 8.4e-05 23.0 0.2 0.00076 20.0 0.1 2.5 3 0 0 3 3 3 1 CoA binding domain NAAA-beta PF15508.6 EMR70524.1 - 1.3e-11 44.6 0.1 2.4e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Candida_ALS PF05792.13 EMR70525.1 - 2.8 8.6 27.5 1 10.0 23.5 2.5 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) 5_nucleotid_C PF02872.18 EMR70526.1 - 1.4e-34 119.6 0.1 5.8e-34 117.6 0.0 2.0 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EMR70526.1 - 1e-10 42.5 1.4 2.6e-10 41.1 0.3 2.1 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 EMR70526.1 - 0.042 13.2 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 YmdB-like protein PGA_cap PF09587.10 EMR70526.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap AAA PF00004.29 EMR70527.1 - 5.6e-41 140.1 0.0 1.1e-40 139.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EMR70527.1 - 1.1e-11 44.4 0.2 2.5e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EMR70527.1 - 5.2e-11 42.2 1.0 9.8e-11 41.3 1.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EMR70527.1 - 4.5e-06 26.9 0.0 9.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMR70527.1 - 9.7e-06 25.9 0.1 0.0066 16.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EMR70527.1 - 1.5e-05 24.3 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EMR70527.1 - 0.00019 21.5 0.1 0.00066 19.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMR70527.1 - 0.00034 21.0 0.2 0.0073 16.7 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EMR70527.1 - 0.00046 20.0 0.0 0.00094 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 EMR70527.1 - 0.00075 19.1 0.3 0.0056 16.3 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 EMR70527.1 - 0.0012 19.1 0.2 0.028 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMR70527.1 - 0.0023 18.5 0.2 0.0055 17.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EMR70527.1 - 0.0054 17.0 1.4 0.0095 16.2 0.0 2.1 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 EMR70527.1 - 0.018 14.5 1.5 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 EMR70527.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EMR70527.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EMR70527.1 - 0.028 13.6 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EMR70527.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR70527.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EMR70527.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EMR70527.1 - 0.067 13.1 0.1 0.63 9.9 0.1 2.3 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 EMR70527.1 - 0.079 12.3 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 EMR70527.1 - 0.086 12.4 1.1 0.59 9.7 0.4 2.5 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMR70527.1 - 0.086 12.1 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EMR70527.1 - 0.16 11.7 1.0 0.34 10.6 0.3 2.0 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EMR70527.1 - 0.19 11.0 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HHH PF00633.23 EMR70528.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HhH-GPD PF00730.25 EMR70528.1 - 0.078 13.4 0.0 0.12 12.9 0.0 1.4 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein MFS_1 PF07690.16 EMR70529.1 - 4e-44 151.0 40.8 4e-44 151.0 40.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR70529.1 - 7.3e-13 48.2 22.0 9.2e-13 47.8 8.2 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.18 EMR70530.1 - 8.6e-07 28.3 0.0 1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3327 PF11806.8 EMR70530.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) Peptidase_C2 PF00648.21 EMR70531.1 - 5.4e-58 196.4 0.2 2.5e-39 135.1 0.1 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Glyco_hydro_3_C PF01915.22 EMR70532.1 - 6.6e-41 140.5 0.0 1.5e-40 139.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR70532.1 - 2.4e-32 112.6 0.0 4.6e-32 111.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR70532.1 - 1.5e-24 85.9 0.2 3.4e-24 84.8 0.1 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain Tannase PF07519.11 EMR70533.1 - 1.2e-113 380.6 0.1 1.4e-113 380.3 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EMR70533.1 - 6.6e-05 22.3 0.0 0.0014 17.9 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR70533.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR70533.1 - 0.12 11.8 0.4 0.22 10.9 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Dyp_perox PF04261.12 EMR70534.1 - 2.7e-08 33.2 0.0 6.8e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Dyp-type peroxidase family Abhydrolase_1 PF00561.20 EMR70535.1 - 3.3e-16 59.7 0.0 3.8e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR70535.1 - 2.3e-11 43.4 0.0 2.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR70535.1 - 3e-10 41.1 0.0 4.9e-10 40.4 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family adh_short PF00106.25 EMR70536.1 - 1.5e-14 53.9 0.0 0.00026 20.5 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70536.1 - 2.5e-06 27.2 0.0 0.0066 16.0 0.0 2.5 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70536.1 - 0.28 11.1 1.8 1.1 9.1 0.6 2.4 2 1 1 3 3 3 0 KR domain adh_short_C2 PF13561.6 EMR70537.1 - 1.8e-49 168.4 0.1 1.2e-41 142.8 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR70537.1 - 2.3e-43 148.0 0.1 2.8e-43 147.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR70537.1 - 1.5e-12 47.8 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR70537.1 - 4.8e-05 22.6 0.0 6.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein LPMO_10 PF03067.15 EMR70538.1 - 1.2e-06 29.4 0.1 9.1e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading VMR2 PF17055.5 EMR70538.1 - 0.039 13.7 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Viral matrix protein M2 SpoVAB PF13782.6 EMR70539.1 - 0.015 15.6 0.2 0.036 14.4 0.2 1.7 1 0 0 1 1 1 0 Stage V sporulation protein AB gpUL132 PF11359.8 EMR70539.1 - 0.24 10.9 1.7 0.33 10.5 0.2 1.7 1 1 1 2 2 2 0 Glycoprotein UL132 PDR_CDR PF06422.12 EMR70539.1 - 3.4 7.6 5.8 7.2 6.6 1.9 2.9 2 1 0 2 2 2 0 CDR ABC transporter TTL PF03133.15 EMR70540.1 - 1.1e-35 123.2 0.0 1.4e-34 119.6 0.0 2.2 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EMR70540.1 - 3.3e-05 23.3 0.0 6.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 EMR70540.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 EMR70540.1 - 0.063 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp p450 PF00067.22 EMR70541.1 - 4.2e-15 55.4 0.0 4.4e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 EMR70543.1 - 2.5e-22 79.6 0.0 2.9e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR70543.1 - 5.1e-16 59.1 0.0 3.4e-15 56.4 0.0 2.0 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EMR70543.1 - 0.004 16.7 0.1 0.053 13.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EMR70543.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sod_Fe_C PF02777.18 EMR70544.1 - 1.5e-35 121.4 0.4 2.9e-35 120.5 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMR70544.1 - 3.5e-33 113.9 1.3 9.5e-33 112.5 0.4 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Med25_VWA PF11265.8 EMR70544.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A Ank_4 PF13637.6 EMR70545.1 - 1.1e-14 54.5 0.1 5.7e-10 39.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR70545.1 - 2.1e-11 43.0 0.1 1.2e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EMR70545.1 - 3e-11 43.3 0.1 2.9e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR70545.1 - 1.5e-10 41.5 0.1 3e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EMR70545.1 - 5.2e-10 39.3 0.3 2.1e-08 34.3 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Flexi_CP_N PF08358.10 EMR70545.1 - 0.02 14.9 0.2 0.097 12.7 0.0 2.0 2 0 0 2 2 2 0 Carlavirus coat PglD_N PF17836.1 EMR70545.1 - 0.076 13.7 0.0 0.25 12.0 0.0 1.7 2 0 0 2 2 2 0 PglD N-terminal domain Acetyltransf_1 PF00583.25 EMR70546.1 - 0.0097 16.1 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EMR70546.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Helo_like_N PF17111.5 EMR70547.1 - 0.015 14.7 0.4 0.024 14.0 0.4 1.4 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins YlbD_coat PF14071.6 EMR70547.1 - 0.15 12.3 0.3 1.5 9.1 0.0 2.4 1 1 2 3 3 3 0 Putative coat protein CH PF00307.31 EMR70548.1 - 2.5e-14 53.3 0.0 4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.16 EMR70549.1 - 3.2e-08 34.3 0.1 3.2e-08 34.3 0.1 2.7 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Acetyltransf_1 PF00583.25 EMR70550.1 - 1.6e-10 41.2 0.0 1.8e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR70550.1 - 1.9e-08 34.3 0.0 2.8e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR70550.1 - 3.6e-06 27.3 0.0 3.1e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR70550.1 - 0.017 15.2 0.0 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF835 PF05763.12 EMR70550.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF835) IMUP PF15761.5 EMR70551.1 - 5.6 7.7 8.3 8.7 7.1 8.3 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EMR70551.1 - 6.4 6.3 8.5 8.8 5.9 8.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bac_rhodopsin PF01036.18 EMR70552.1 - 8.7e-30 104.0 19.6 1e-29 103.7 19.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PHD PF00628.29 EMR70553.1 - 1e-05 25.3 8.4 1.7e-05 24.6 8.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-C4pol PF14260.6 EMR70553.1 - 0.48 10.9 2.3 7.1 7.2 0.6 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Arrestin_N PF00339.29 EMR70554.1 - 2.9e-05 24.1 0.0 9e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Fungal_trans PF04082.18 EMR70555.1 - 0.17 10.9 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain OTU PF02338.19 EMR70556.1 - 4.2e-05 24.0 0.0 0.0001 22.8 0.0 1.6 1 1 1 2 2 2 1 OTU-like cysteine protease adh_short PF00106.25 EMR70557.1 - 2.9e-29 101.9 0.0 4e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70557.1 - 2.1e-20 73.3 0.0 2.7e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70557.1 - 1.5e-08 34.8 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR70557.1 - 0.0056 16.2 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Beta-lactamase PF00144.24 EMR70557.1 - 0.022 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase BBE PF08031.12 EMR70559.1 - 4.8e-10 39.4 1.3 4.8e-10 39.4 1.3 1.8 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.23 EMR70559.1 - 3.5e-09 36.5 3.3 3.5e-09 36.5 3.3 1.9 2 0 0 2 2 2 1 FAD binding domain ddrB-ParB PF18763.1 EMR70561.1 - 0.13 12.4 2.0 0.23 11.6 2.0 1.3 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain NYN PF01936.18 EMR70562.1 - 0.0001 22.8 0.0 0.0028 18.2 0.0 2.2 1 1 0 1 1 1 1 NYN domain RTA1 PF04479.13 EMR70563.1 - 1.8e-38 132.2 5.0 6.7e-38 130.4 5.0 1.8 1 1 0 1 1 1 1 RTA1 like protein DUF3995 PF13160.6 EMR70563.1 - 0.029 14.7 1.2 0.029 14.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF308 PF03729.13 EMR70563.1 - 0.056 13.8 3.3 0.14 12.5 1.6 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF572 PF04502.13 EMR70564.1 - 3.6e-21 76.2 20.0 1.2e-12 48.2 0.9 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF572) DUF4407 PF14362.6 EMR70564.1 - 8.3 5.7 8.6 11 5.3 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EI24 PF07264.11 EMR70565.1 - 1.9e-11 44.5 0.1 5.3e-11 43.1 0.1 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2062 PF09835.9 EMR70565.1 - 0.025 14.4 2.9 0.51 10.2 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Importin_rep_4 PF18808.1 EMR70566.1 - 5.2e-31 106.8 1.2 5.2e-31 106.8 1.2 5.5 5 1 1 6 6 6 1 Importin repeat HEAT_EZ PF13513.6 EMR70566.1 - 2.4e-20 72.6 9.5 1.7e-10 41.2 0.2 7.6 7 1 1 8 8 6 3 HEAT-like repeat HEAT_2 PF13646.6 EMR70566.1 - 2.8e-14 53.3 12.2 4.7e-05 23.7 0.0 7.3 5 2 3 8 8 8 3 HEAT repeats HEAT PF02985.22 EMR70566.1 - 3e-14 51.9 15.3 0.0029 17.7 0.0 10.8 12 0 0 12 12 10 2 HEAT repeat Importin_rep_6 PF18829.1 EMR70566.1 - 1.4e-13 50.9 1.4 2.6e-12 46.8 0.2 3.4 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 EMR70566.1 - 3e-12 47.0 0.3 0.016 15.8 0.0 7.2 5 1 3 8 8 7 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 EMR70566.1 - 4.2e-10 39.7 0.0 5.4e-05 23.0 0.0 4.6 3 1 1 4 4 4 3 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 EMR70566.1 - 6.4e-08 32.4 1.8 0.0031 17.1 0.1 5.1 5 1 1 6 6 6 2 CLASP N terminal DRIM PF07539.12 EMR70566.1 - 9.3e-08 30.8 4.7 0.0015 16.9 0.3 4.6 3 2 2 5 5 5 2 Down-regulated in metastasis Cnd1 PF12717.7 EMR70566.1 - 2.1e-07 31.1 0.3 0.011 15.7 0.0 4.5 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EMR70566.1 - 4.8e-07 29.2 2.9 1.2e-06 27.9 0.1 3.0 2 2 1 3 3 3 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EMR70566.1 - 5.9e-06 26.3 1.6 0.18 11.7 0.0 5.8 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) Importin_rep_5 PF18816.1 EMR70566.1 - 1.5e-05 25.2 1.5 0.00021 21.5 0.1 3.2 3 0 0 3 3 3 1 Importin repeat IFRD PF05004.13 EMR70566.1 - 9.4e-05 21.7 0.6 0.034 13.3 0.1 4.2 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) DUF3535 PF12054.8 EMR70566.1 - 0.00013 21.3 1.7 0.00058 19.2 0.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) Adaptin_N PF01602.20 EMR70566.1 - 0.00023 19.9 5.8 0.058 11.9 0.6 3.9 3 1 1 4 4 4 1 Adaptin N terminal region RTP1_C1 PF10363.9 EMR70566.1 - 0.00066 19.8 0.5 0.12 12.6 0.2 4.0 4 1 0 5 5 3 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 EMR70566.1 - 0.00076 19.5 3.9 2.1 8.3 0.2 4.1 5 0 0 5 5 3 2 Myosin-binding striated muscle assembly central TFCD_C PF12612.8 EMR70566.1 - 0.0027 17.6 0.2 5.9 6.7 0.0 3.9 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal Telomere_reg-2 PF10193.9 EMR70566.1 - 0.0027 18.1 2.2 0.022 15.2 0.9 2.8 2 0 0 2 2 2 1 Telomere length regulation protein V-ATPase_H_N PF03224.14 EMR70566.1 - 0.0048 16.2 3.5 0.15 11.3 0.1 3.0 2 1 0 3 3 3 1 V-ATPase subunit H DUF4042 PF13251.6 EMR70566.1 - 0.0095 15.7 0.1 1.8 8.2 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) IBN_N PF03810.19 EMR70566.1 - 0.012 15.5 0.6 0.081 12.9 0.1 2.9 3 0 0 3 3 3 0 Importin-beta N-terminal domain Cnd3 PF12719.7 EMR70566.1 - 0.023 13.9 0.0 0.43 9.7 0.0 2.6 1 1 1 2 2 2 0 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 EMR70566.1 - 0.033 14.5 0.0 6.7 7.1 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DNA_alkylation PF08713.11 EMR70566.1 - 0.083 12.6 4.0 0.17 11.6 0.0 3.2 3 1 0 3 3 3 0 DNA alkylation repair enzyme CAS_CSE1 PF03378.15 EMR70566.1 - 0.11 11.0 0.1 2.2 6.6 0.1 2.8 1 1 2 3 3 3 0 CAS/CSE protein, C-terminus Arm PF00514.23 EMR70566.1 - 1.2 9.2 11.7 4.5 7.5 0.0 5.0 6 0 0 6 6 3 0 Armadillo/beta-catenin-like repeat Bromodomain PF00439.25 EMR70567.1 - 3e-37 126.6 2.3 5.5e-19 68.0 0.2 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EMR70567.1 - 1.5e-17 63.6 2.2 4.9e-17 61.9 1.1 2.2 2 0 0 2 2 2 1 BAH domain SSPI PF14098.6 EMR70567.1 - 0.15 12.2 0.1 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 Small, acid-soluble spore protein I Ribosomal_L30_N PF08079.12 EMR70567.1 - 1.4 9.2 21.3 0.059 13.6 3.6 2.7 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain CDC45 PF02724.14 EMR70567.1 - 3.3 5.9 17.5 0.033 12.5 6.8 2.3 2 0 0 2 2 2 0 CDC45-like protein MscS_TM PF12794.7 EMR70567.1 - 7.6 5.3 4.6 13 4.5 4.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FmdA_AmdA PF03069.15 EMR70568.1 - 8.2e-173 574.5 0.0 9.6e-173 574.2 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family 2OG-FeII_Oxy_2 PF13532.6 EMR70570.1 - 2.7e-27 96.3 0.0 4.7e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Met_10 PF02475.16 EMR70571.1 - 9.5e-48 162.6 0.0 1.5e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Adaptin_binding PF10199.9 EMR70572.1 - 4.1e-14 53.2 4.4 8.4e-14 52.2 4.4 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Cupin_2 PF07883.11 EMR70573.1 - 2.3e-11 43.2 0.4 4e-11 42.5 0.2 1.5 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EMR70573.1 - 4.5e-07 29.6 0.0 5.4e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EMR70573.1 - 0.00029 20.5 0.1 0.00061 19.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 EMR70573.1 - 0.0031 17.4 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 EMR70573.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.5 1 1 1 2 2 2 0 Cupin UPF0258 PF06789.12 EMR70574.1 - 0.013 15.6 11.5 0.57 10.3 6.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0258) DNA_meth_N PF18284.1 EMR70574.1 - 0.028 14.3 11.5 0.63 10.0 1.8 3.8 1 1 3 4 4 4 0 DNA methylase N-terminal domain zinc_ribbon_6 PF14599.6 EMR70574.1 - 0.4 10.7 5.9 11 6.1 0.3 3.5 1 1 2 4 4 4 0 Zinc-ribbon Cyclophil_like2 PF18050.1 EMR70574.1 - 0.74 9.8 5.2 7.5 6.5 0.4 2.1 1 1 1 2 2 2 0 Cyclophilin-like family SEP PF08059.13 EMR70574.1 - 2.6 8.7 5.7 5 7.8 1.9 2.3 1 1 1 2 2 2 0 SEP domain zinc_ribbon_6 PF14599.6 EMR70576.1 - 0.89 9.6 4.6 8.7 6.4 0.1 3.0 2 1 1 3 3 3 0 Zinc-ribbon Peptidase_M76 PF09768.9 EMR70577.1 - 2.5e-67 225.9 3.1 3.1e-67 225.6 3.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EMR70577.1 - 0.0046 16.8 0.2 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 SprT-like family Peptidase_M91 PF14891.6 EMR70577.1 - 0.079 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Effector protein PRIMA1 PF16101.5 EMR70577.1 - 7.8 6.6 11.3 0.7 9.9 6.3 1.8 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 DUF2040 PF09745.9 EMR70579.1 - 2e-38 131.2 22.5 2e-38 131.2 22.5 3.8 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Abhydrolase_1 PF00561.20 EMR70580.1 - 1.8e-18 67.1 0.1 7.7e-16 58.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EMR70580.1 - 1.1e-15 57.6 0.0 2.2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Egh16-like PF11327.8 EMR70581.1 - 1.3e-24 87.7 9.3 1.3e-24 87.7 9.3 1.8 2 1 0 2 2 2 1 Egh16-like virulence factor V-set PF07686.17 EMR70581.1 - 0.012 15.7 0.1 0.056 13.6 0.1 2.1 2 0 0 2 2 2 0 Immunoglobulin V-set domain DGF-1_5 PF11038.8 EMR70581.1 - 0.022 14.1 0.3 0.034 13.5 0.3 1.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Secretin_N_2 PF07655.13 EMR70581.1 - 2.2 8.9 16.4 11 6.6 16.4 2.2 1 0 0 1 1 1 0 Secretin N-terminal domain MFS_1 PF07690.16 EMR70582.1 - 1.8e-32 112.7 25.8 2.6e-32 112.1 25.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR70582.1 - 6.6e-05 22.4 4.4 6.6e-05 22.4 4.4 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1180 PF06679.12 EMR70582.1 - 0.17 12.3 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) zf-Tim10_DDP PF02953.15 EMR70583.1 - 9e-22 76.5 4.1 1.1e-21 76.3 4.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DDE_1 PF03184.19 EMR70583.1 - 0.019 14.6 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3398 PF11878.8 EMR70583.1 - 0.031 14.7 1.4 0.1 13.0 1.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) Ins_beta PF03488.14 EMR70583.1 - 0.04 13.9 0.6 0.065 13.3 0.6 1.3 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Hydrolase_3 PF08282.12 EMR70584.1 - 4.3e-11 43.0 0.0 1.1e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PMM PF03332.13 EMR70584.1 - 5e-10 39.5 0.0 6.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase PF00702.26 EMR70584.1 - 0.00062 20.1 0.2 0.0083 16.4 0.0 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EMR70584.1 - 0.00081 19.0 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 EMR70584.1 - 0.16 12.1 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Stb3 PF10330.9 EMR70585.1 - 0.0069 16.4 0.8 0.019 15.0 0.8 1.7 1 0 0 1 1 1 1 Putative Sin3 binding protein zf-primase PF09329.11 EMR70585.1 - 0.019 14.8 0.6 0.04 13.7 0.6 1.5 1 0 0 1 1 1 0 Primase zinc finger Y_Y_Y PF07495.13 EMR70585.1 - 0.18 11.8 1.0 0.46 10.5 1.0 1.6 1 0 0 1 1 1 0 Y_Y_Y domain ABC_tran PF00005.27 EMR70586.1 - 6.8e-26 91.4 0.0 1.1e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMR70586.1 - 0.00012 22.1 0.2 0.00024 21.1 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EMR70586.1 - 0.0023 17.8 0.0 0.063 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMR70586.1 - 0.027 14.2 0.7 0.06 13.1 0.7 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EMR70586.1 - 0.031 13.9 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EMR70586.1 - 0.041 14.0 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 EMR70586.1 - 0.077 13.1 0.4 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 EMR70586.1 - 0.15 12.2 1.3 0.25 11.4 1.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EMR70586.1 - 0.16 11.3 0.2 0.27 10.5 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Septin PF00735.18 EMR70586.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Septin IIGP PF05049.13 EMR70586.1 - 0.25 10.4 0.2 0.38 9.8 0.2 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC2_membrane_3 PF12698.7 EMR70586.1 - 1.5 7.9 11.1 2.3 7.3 11.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein UPF0113_N PF17833.1 EMR70588.1 - 2.5e-25 88.8 0.0 3.6e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EMR70588.1 - 4.1e-14 52.6 0.0 6.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain Methyltranf_PUA PF13636.6 EMR70588.1 - 0.093 12.7 0.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF GST_C_2 PF13410.6 EMR70590.1 - 0.032 14.2 0.1 0.091 12.8 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Asparaginase PF00710.20 EMR70592.1 - 2.9e-30 105.2 0.0 5.2e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EMR70592.1 - 5e-09 36.4 0.4 2.1e-08 34.4 0.1 2.0 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain PA PF02225.22 EMR70592.1 - 0.1 12.6 0.3 0.34 11.0 0.3 1.9 1 0 0 1 1 1 0 PA domain Fungal_lectin PF07938.12 EMR70593.1 - 3.5e-07 29.9 0.0 4.7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Fungal fucose-specific lectin Glyco_hydro_7 PF00840.20 EMR70594.1 - 9.3e-182 604.6 9.5 1e-181 604.4 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3517 PF12030.8 EMR70596.1 - 4.7e-112 374.2 0.0 7.1e-112 373.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 EMR70596.1 - 7.9e-25 87.8 0.0 1.4e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMR70596.1 - 1.5e-15 57.6 0.0 3.5e-15 56.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 EMR70597.1 - 2.4e-69 233.7 0.0 3e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR70597.1 - 2.8e-42 144.8 0.0 3.8e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR70597.1 - 7.7e-07 28.7 0.0 1.8e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMR70597.1 - 0.00034 20.0 0.1 0.00057 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EMR70597.1 - 0.021 14.4 0.0 0.1 12.2 0.0 1.8 1 1 1 2 2 2 0 RIO1 family FTA2 PF13095.6 EMR70597.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EMR70597.1 - 0.12 12.2 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EMR70597.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 EMR70597.1 - 0.23 10.5 0.0 0.41 9.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SNF2_N PF00176.23 EMR70599.1 - 2.4e-74 250.2 0.0 3.2e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR70599.1 - 2.3e-16 60.1 0.0 4.9e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR70599.1 - 4.1e-05 23.6 0.0 8.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EMR70599.1 - 0.00045 20.0 12.3 0.00089 19.1 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 EMR70599.1 - 0.0013 18.0 0.2 0.0021 17.3 0.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_2 PF13923.6 EMR70599.1 - 0.0026 17.6 9.4 0.0058 16.4 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR70599.1 - 0.0034 17.2 10.1 0.0062 16.4 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMR70599.1 - 0.0083 16.4 12.9 0.0083 16.4 12.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EMR70599.1 - 0.079 13.0 10.9 0.17 11.9 10.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EMR70599.1 - 0.45 10.5 11.2 1.1 9.3 11.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_hydro_36 PF17167.4 EMR70600.1 - 3.9e-58 197.1 0.0 9e-58 195.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 EMR70600.1 - 5.1e-28 98.2 0.0 7.9e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 EMR70600.1 - 0.041 13.1 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_65C PF03633.15 EMR70600.1 - 0.15 12.0 0.0 0.49 10.3 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain p450 PF00067.22 EMR70602.1 - 1.9e-72 244.5 0.0 2.3e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_kinase PF00696.28 EMR70603.1 - 8.3e-40 136.9 2.6 1.1e-39 136.4 2.6 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EMR70603.1 - 4.6e-15 55.3 0.1 1.3e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 PUA domain 2OG-FeII_Oxy PF03171.20 EMR70604.1 - 1.1e-10 41.9 0.0 2.2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMR70604.1 - 6.3e-10 39.8 0.0 1.2e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal GTP_EFTU PF00009.27 EMR70605.1 - 1.4e-18 67.1 0.0 2.8e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EMR70605.1 - 5.1e-09 36.4 2.1 2.3e-08 34.3 2.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EMR70605.1 - 0.00036 20.8 0.0 0.0009 19.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EMR70605.1 - 0.0017 18.4 0.4 0.0061 16.6 0.4 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR70605.1 - 0.0051 16.7 0.8 0.95 9.3 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EMR70605.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Dynamin family AAA PF00004.29 EMR70606.1 - 7.4e-48 162.3 0.0 4.6e-41 140.3 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMR70606.1 - 7.4e-08 32.1 0.0 2.6e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EMR70606.1 - 1.2e-06 29.1 0.3 0.00039 20.8 0.2 3.3 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EMR70606.1 - 6.1e-06 26.1 0.0 7.3e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EMR70606.1 - 3e-05 24.2 0.0 8.7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 EMR70606.1 - 0.00014 22.0 0.0 0.63 10.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 EMR70606.1 - 0.0006 19.8 0.0 0.0022 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EMR70606.1 - 0.0045 16.2 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EMR70606.1 - 0.0048 17.2 0.2 0.17 12.2 0.2 2.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMR70606.1 - 0.009 16.4 0.0 0.042 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 EMR70606.1 - 0.022 14.5 2.9 0.23 11.2 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 EMR70606.1 - 0.023 14.9 0.0 0.086 13.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMR70606.1 - 0.024 15.2 0.0 0.095 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EMR70606.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EMR70606.1 - 0.058 12.8 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EMR70606.1 - 0.11 12.2 0.0 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Bromodomain PF00439.25 EMR70606.1 - 0.12 12.4 0.1 0.41 10.8 0.1 1.8 1 0 0 1 1 1 0 Bromodomain NACHT PF05729.12 EMR70606.1 - 0.16 11.9 0.1 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DUF4604 PF15377.6 EMR70607.1 - 8.6e-35 120.7 14.0 9.8e-35 120.5 14.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) GEN1_C PF18380.1 EMR70607.1 - 7.1 7.6 8.7 26 5.8 2.0 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain UbiA PF01040.18 EMR70608.1 - 8.1e-22 77.7 13.3 2.1e-21 76.4 13.6 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family RuvX PF03652.15 EMR70609.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction resolvase DUF148 PF02520.17 EMR70609.1 - 0.22 11.6 2.0 14 5.8 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF148 LDB19 PF13002.7 EMR70610.1 - 3.1e-38 131.4 0.2 6.5e-38 130.4 0.2 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Spo0M PF07070.11 EMR70610.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein Metallopep PF12044.8 EMR70611.1 - 1e-92 311.0 0.0 1.3e-92 310.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Arginase PF00491.21 EMR70612.1 - 4.3e-69 233.1 0.1 4.8e-69 233.0 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EMR70612.1 - 0.082 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Chs7 PF12271.8 EMR70613.1 - 1.9e-122 408.1 14.4 2.2e-122 407.9 14.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 EMR70613.1 - 0.022 15.0 0.6 0.022 15.0 0.6 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF3382) AA_permease PF00324.21 EMR70614.1 - 4.8e-108 361.8 40.9 6.1e-108 361.5 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR70614.1 - 1.8e-29 102.9 43.8 2.1e-29 102.6 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease NOC3p PF07540.11 EMR70615.1 - 9.4e-30 102.9 0.2 4.1e-29 100.9 0.2 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 EMR70615.1 - 2.8e-23 82.8 0.0 2.8e-23 82.8 0.0 2.9 2 1 0 2 2 2 1 CBF/Mak21 family WcbI PF18588.1 EMR70615.1 - 0.081 12.5 0.1 1.2 8.8 0.2 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI DUF2514 PF10721.9 EMR70615.1 - 1.3 9.0 13.4 0.045 13.8 6.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) EF-hand_1 PF00036.32 EMR70616.1 - 5e-19 66.4 12.5 1.2e-07 30.8 0.8 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EMR70616.1 - 1.3e-16 60.8 5.4 1e-14 54.7 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EMR70616.1 - 3.1e-14 51.6 4.3 4.2e-05 23.2 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EMR70616.1 - 1.9e-12 46.1 8.1 8.7e-07 28.2 0.4 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EMR70616.1 - 9.4e-11 41.4 9.2 6.5e-05 22.7 0.5 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EMR70616.1 - 3.8e-06 26.8 7.3 0.001 19.0 0.6 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EMR70616.1 - 0.00014 22.2 0.1 0.00026 21.3 0.1 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EMR70616.1 - 0.027 14.7 2.3 0.046 13.9 0.8 2.2 2 1 1 3 3 3 0 Dockerin type I domain EF-hand_9 PF14658.6 EMR70616.1 - 0.028 14.7 0.0 1.5 9.2 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain Peptidase_M22 PF00814.25 EMR70618.1 - 7.2e-78 262.0 0.0 8.7e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EMR70618.1 - 0.062 13.0 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Pkinase PF00069.25 EMR70619.1 - 1.6e-62 211.3 0.0 2e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR70619.1 - 1.6e-27 96.4 0.0 2.4e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR70619.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EMR70619.1 - 0.021 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EMR70619.1 - 0.056 13.1 0.0 0.32 10.6 0.0 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EMR70619.1 - 0.066 12.5 0.0 0.26 10.6 0.0 1.9 2 1 0 2 2 2 0 Kinase-like EPL1 PF10513.9 EMR70620.1 - 4.1e-17 63.0 4.1 4.1e-17 63.0 4.1 2.5 2 1 0 2 2 2 1 Enhancer of polycomb-like DUF2199 PF09965.9 EMR70620.1 - 0.026 14.6 0.1 0.066 13.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Mei5 PF10376.9 EMR70621.1 - 0.078 12.8 5.1 0.14 12.0 4.9 1.5 1 1 0 1 1 1 0 Double-strand recombination repair protein Histidinol_dh PF00815.20 EMR70621.1 - 0.24 10.4 2.5 0.28 10.2 2.5 1.0 1 0 0 1 1 1 0 Histidinol dehydrogenase Glyco_hydro_61 PF03443.14 EMR70622.1 - 4.2e-59 199.9 0.0 5.1e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 G-patch PF01585.23 EMR70623.1 - 7.5e-07 28.9 0.0 4.8e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EMR70623.1 - 0.00095 19.2 0.0 0.00095 19.2 0.0 4.3 2 1 1 3 3 3 1 G-patch domain Mitofilin PF09731.9 EMR70623.1 - 0.091 11.6 34.8 0.14 11.0 34.8 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.9 EMR70623.1 - 0.93 8.0 27.8 1.4 7.4 27.8 1.4 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 EMR70623.1 - 5.7 3.9 27.8 7.2 3.6 27.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AA_permease PF00324.21 EMR70624.1 - 8.2e-130 433.6 49.7 9.6e-130 433.4 49.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR70624.1 - 1.1e-31 110.2 55.7 1.5e-31 109.7 55.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3500 PF12006.8 EMR70625.1 - 1.9e-109 365.8 0.0 2.2e-109 365.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DOG1 PF14144.6 EMR70625.1 - 1.8 8.9 3.7 89 3.4 0.0 3.8 3 1 0 3 3 3 0 Seed dormancy control RmlD_sub_bind PF04321.17 EMR70627.1 - 4e-14 52.4 0.0 1.4e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EMR70627.1 - 8.1e-14 51.7 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMR70627.1 - 0.00032 19.9 0.0 0.00061 19.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMR70627.1 - 0.00056 19.4 0.0 0.0022 17.5 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMR70627.1 - 0.024 13.7 0.0 0.14 11.1 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EMR70627.1 - 0.19 11.2 0.1 0.43 10.0 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase DUF3209 PF11483.8 EMR70628.1 - 0.06 13.8 0.4 0.18 12.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) ACT_6 PF13740.6 EMR70628.1 - 0.18 11.8 0.0 0.5 10.4 0.0 1.7 1 0 0 1 1 1 0 ACT domain Macoilin PF09726.9 EMR70628.1 - 0.44 9.1 9.2 0.69 8.4 9.2 1.4 1 1 0 1 1 1 0 Macoilin family Peptidase_S49_N PF08496.10 EMR70628.1 - 0.63 10.1 6.6 1.2 9.1 6.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MFS_1 PF07690.16 EMR70629.1 - 5.6e-37 127.5 41.5 1e-32 113.5 23.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR70629.1 - 5.7e-14 51.8 9.0 5.7e-14 51.8 9.0 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter RseC_MucC PF04246.12 EMR70629.1 - 1.4 8.9 9.6 0.31 11.0 1.0 3.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC UL17 PF17640.2 EMR70631.1 - 0.017 15.1 0.2 0.045 13.8 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized UL17 Fungal_lectin PF07938.12 EMR70633.1 - 1.1e-07 31.5 0.0 0.0045 16.4 0.0 2.2 2 0 0 2 2 2 2 Fungal fucose-specific lectin DPPIV_N PF00930.21 EMR70634.1 - 6.2e-110 367.3 0.3 8.2e-110 366.9 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EMR70634.1 - 3.8e-54 183.4 2.8 6.4e-54 182.7 2.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EMR70634.1 - 0.0004 20.1 2.4 0.0055 16.3 1.2 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EMR70634.1 - 0.13 11.8 0.0 6.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Polysacc_deac_1 PF01522.21 EMR70635.1 - 5.5e-16 58.6 0.0 1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMR70635.1 - 0.0037 16.9 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) ThuA PF06283.11 EMR70635.1 - 0.032 14.4 0.1 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Trehalose utilisation Carb_kinase PF01256.17 EMR70643.1 - 4.2e-55 186.9 0.0 6.4e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EMR70643.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase HK PF02110.15 EMR70643.1 - 0.023 14.1 0.0 0.052 12.9 0.0 1.6 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family ATP-synt_ab PF00006.25 EMR70644.1 - 2.9e-66 223.2 0.0 2.9e-41 141.5 0.0 2.3 1 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EMR70644.1 - 1.5e-45 154.6 0.2 2.6e-45 153.8 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EMR70644.1 - 4.6e-15 55.9 3.0 1.2e-14 54.6 3.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DAO PF01266.24 EMR70645.1 - 4.7e-18 65.9 0.1 5.3e-18 65.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF4988 PF16378.5 EMR70645.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Pyr_redox_3 PF13738.6 EMR70645.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMR70645.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Transferase PF02458.15 EMR70648.1 - 3.3e-33 115.0 0.0 1.2e-32 113.2 0.0 1.7 1 1 0 1 1 1 1 Transferase family NmrA PF05368.13 EMR70649.1 - 1.1e-21 77.4 0.0 1.6e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR70649.1 - 5.7e-18 65.4 0.0 8.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR70649.1 - 1.9e-06 27.6 0.5 0.00013 21.5 0.5 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMR70649.1 - 0.0085 15.2 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EMR70649.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.20 EMR70649.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AAA_lid_1 PF17857.1 EMR70649.1 - 0.094 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA+ lid domain Shikimate_DH PF01488.20 EMR70649.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rsm22 PF09243.10 EMR70652.1 - 1e-30 107.0 0.0 2.2e-29 102.6 0.0 2.7 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Thioredoxin PF00085.20 EMR70652.1 - 8.2e-25 86.8 0.0 1.5e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Methyltransf_23 PF13489.6 EMR70652.1 - 2e-05 24.5 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain OST3_OST6 PF04756.13 EMR70652.1 - 4.7e-05 22.9 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EMR70652.1 - 0.00012 22.3 0.0 0.00029 21.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EMR70652.1 - 0.00037 20.9 0.0 0.00097 19.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Methyltransf_12 PF08242.12 EMR70652.1 - 0.0063 17.2 0.1 0.042 14.6 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Thioredoxin_7 PF13899.6 EMR70652.1 - 0.03 14.5 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 EMR70652.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family NodS PF05401.11 EMR70652.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Thioredoxin_9 PF14595.6 EMR70652.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin PSK_trans_fac PF07704.11 EMR70652.1 - 0.61 10.9 4.5 6.1 7.7 1.3 2.8 2 0 0 2 2 2 0 Rv0623-like transcription factor Cadherin_C_2 PF16492.5 EMR70653.1 - 0.0024 18.6 1.0 0.46 11.3 0.0 3.0 3 0 0 3 3 3 2 Cadherin cytoplasmic C-terminal Glyco_transf_90 PF05686.12 EMR70654.1 - 2.2e-11 43.3 1.0 2.5e-08 33.2 0.0 2.9 3 0 0 3 3 3 3 Glycosyl transferase family 90 PhyH PF05721.13 EMR70655.1 - 4.9e-16 59.6 0.0 7.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.22 EMR70656.1 - 6.3e-36 124.1 0.0 8.5e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EMR70657.1 - 2e-12 47.2 0.0 4.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR70657.1 - 0.00099 20.2 0.0 0.0016 19.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR70657.1 - 0.0012 18.7 0.0 0.016 15.1 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EMR70657.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Amidohydro_2 PF04909.14 EMR70658.1 - 2.5e-13 50.5 2.2 7.1e-11 42.4 2.2 2.2 1 1 0 1 1 1 1 Amidohydrolase Cupin_2 PF07883.11 EMR70659.1 - 4.9e-10 39.0 0.1 4.9e-10 39.0 0.1 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EMR70659.1 - 2.7e-06 27.1 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EMR70659.1 - 0.0039 17.1 0.1 0.0069 16.3 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain JmjC PF02373.22 EMR70659.1 - 0.0087 16.5 0.1 0.075 13.5 0.1 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase FAD_binding_3 PF01494.19 EMR70660.1 - 3.2e-15 56.2 0.1 8.2e-13 48.3 0.1 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR70660.1 - 0.0039 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR70660.1 - 0.042 13.1 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR70660.1 - 0.062 12.9 1.6 0.15 11.7 1.0 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Helo_like_N PF17111.5 EMR70661.1 - 4.1e-15 55.7 0.6 8.9e-15 54.6 0.6 1.6 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins TRI5 PF06330.11 EMR70663.1 - 2.1e-17 63.1 0.0 2.8e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Abhydrolase_1 PF00561.20 EMR70664.1 - 6e-19 68.7 0.0 2.3e-18 66.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EMR70664.1 - 4.7e-08 33.1 0.0 9.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein p450 PF00067.22 EMR70665.1 - 3.5e-62 210.7 0.0 2.1e-42 145.5 0.1 2.8 1 1 1 2 2 2 2 Cytochrome P450 Caps_synth PF05704.12 EMR70666.1 - 1.5e-13 50.8 0.0 2.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 EMR70666.1 - 1.4e-05 25.6 0.0 3.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.22 EMR70667.1 - 2.1e-43 148.7 0.0 9.6e-43 146.6 0.0 1.8 1 1 1 2 2 2 1 Cytochrome P450 F-box-like PF12937.7 EMR70667.1 - 0.00035 20.4 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EMR70667.1 - 0.022 14.7 0.1 0.077 13.0 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain F-box PF00646.33 EMR70667.1 - 0.066 13.1 0.1 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 F-box domain HET PF06985.11 EMR70668.1 - 2.9e-21 76.3 0.0 1.1e-16 61.5 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) NKAP PF15692.5 EMR70668.1 - 0.02 15.6 0.3 0.02 15.6 0.3 2.2 2 0 0 2 2 2 0 NF-kappa-B-activating protein CHCH PF06747.13 EMR70669.1 - 3.7e-10 39.7 15.8 7.8e-09 35.5 7.3 2.5 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 EMR70669.1 - 0.00023 21.1 11.1 0.0089 16.0 5.9 2.2 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EMR70669.1 - 0.0032 17.4 11.8 0.093 12.8 0.3 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1672 PF07901.11 EMR70669.1 - 0.25 10.7 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Pet191_N PF10203.9 EMR70669.1 - 0.56 10.6 8.3 19 5.7 3.8 3.0 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 EMR70669.1 - 4.5 7.6 12.7 9.1 6.6 5.8 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.16 EMR70669.1 - 6.4 7.1 10.3 21 5.4 8.8 2.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein GDC-P PF02347.16 EMR70670.1 - 7.4e-170 565.4 0.0 2.5e-156 520.8 0.0 2.6 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EMR70670.1 - 1.9e-06 27.1 0.0 0.0067 15.4 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMR70670.1 - 1.2e-05 24.8 0.0 2.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMR70670.1 - 0.051 12.9 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Nup54 PF13874.6 EMR70671.1 - 2.9e-40 137.6 2.4 2.9e-40 137.6 2.4 2.4 3 0 0 3 3 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EMR70671.1 - 8.4e-15 54.1 8.2 1.6e-14 53.1 8.2 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 EMR70671.1 - 0.00073 20.3 33.5 0.0089 16.9 33.5 2.2 1 1 0 1 1 1 1 Nucleoporin FG repeat region DivIVA PF05103.13 EMR70671.1 - 0.045 13.8 0.4 0.045 13.8 0.4 2.3 3 0 0 3 3 2 0 DivIVA protein HTH_39 PF14090.6 EMR70671.1 - 0.061 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain V-SNARE_C PF12352.8 EMR70671.1 - 0.076 13.3 2.5 3.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Nbl1_Borealin_N PF10444.9 EMR70671.1 - 0.082 12.6 1.3 0.45 10.2 0.1 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal NPV_P10 PF05531.12 EMR70671.1 - 0.099 13.1 5.5 14 6.2 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Myb_DNA-bind_4 PF13837.6 EMR70671.1 - 0.14 12.5 1.2 2 8.8 0.2 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain GAPES3 PF17154.4 EMR70671.1 - 0.2 11.6 2.1 0.21 11.6 0.6 1.8 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain DUF948 PF06103.11 EMR70671.1 - 0.23 11.7 3.8 8.5 6.7 0.1 3.0 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) ABC_tran_CTD PF16326.5 EMR70671.1 - 0.33 11.2 8.9 7.1 7.0 0.0 3.6 4 0 0 4 4 3 0 ABC transporter C-terminal domain Mitofilin PF09731.9 EMR70671.1 - 3.1 6.5 15.7 0.28 10.0 1.9 3.0 3 0 0 3 3 3 0 Mitochondrial inner membrane protein bZIP_1 PF00170.21 EMR70671.1 - 3.6 7.8 10.3 3.1 8.0 0.4 3.7 3 1 1 4 4 4 0 bZIP transcription factor Tape_meas_lam_C PF09718.10 EMR70672.1 - 0.0028 17.7 0.1 0.0056 16.8 0.1 1.5 1 0 0 1 1 1 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ADH_N PF08240.12 EMR70673.1 - 3.9e-05 23.5 1.0 0.00048 20.0 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR70673.1 - 0.001 19.1 1.0 0.0024 17.9 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR70673.1 - 0.14 11.6 0.5 0.23 10.9 0.3 1.5 2 0 0 2 2 2 0 short chain dehydrogenase Abhydrolase_3 PF07859.13 EMR70674.1 - 4.3e-33 114.9 0.0 7.5e-33 114.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 EMR70674.1 - 0.0039 15.9 0.0 0.0053 15.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 EMR70674.1 - 0.006 16.2 0.2 0.044 13.3 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EMR70674.1 - 0.036 13.5 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family tRNA-synt_1e PF01406.19 EMR70674.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Abhydrolase_2 PF02230.16 EMR70674.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cytochrom_C1 PF02167.15 EMR70675.1 - 1.6e-92 309.2 0.0 1.9e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EMR70675.1 - 0.0094 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EMR70675.1 - 0.091 13.9 0.0 0.47 11.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c Pyrophosphatase PF00719.19 EMR70676.1 - 5.7e-58 195.3 0.1 7.8e-58 194.8 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase F_bP_aldolase PF01116.20 EMR70677.1 - 3.3e-82 276.1 0.0 3.8e-82 275.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CobS PF02654.15 EMR70677.1 - 0.017 15.3 0.1 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase Pro_isomerase PF00160.21 EMR70678.1 - 2.9e-49 167.4 0.1 7.3e-49 166.1 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EMR70678.1 - 6e-11 42.7 0.1 6e-05 23.7 0.0 4.9 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR70678.1 - 0.00023 21.4 0.0 0.0033 17.7 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR70678.1 - 0.017 14.1 0.2 0.18 10.7 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5643 PF18705.1 EMR70678.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5643) Sugar_tr PF00083.24 EMR70679.1 - 5.9e-24 84.7 8.6 7.3e-24 84.4 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR70679.1 - 6.2e-05 22.1 15.9 8.5e-05 21.6 15.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Como_LCP PF02247.16 EMR70680.1 - 0.23 10.0 0.1 0.36 9.4 0.1 1.2 1 0 0 1 1 1 0 Large coat protein Fungal_lectin PF07938.12 EMR70682.1 - 1.2e-18 67.6 2.5 2.3e-18 66.6 0.1 2.0 2 0 0 2 2 2 1 Fungal fucose-specific lectin HhH-GPD PF00730.25 EMR70683.1 - 4e-05 24.0 0.0 8.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein FPN1 PF06963.12 EMR70684.1 - 2.4e-69 234.0 9.8 8.7e-44 149.8 3.5 2.0 2 0 0 2 2 2 2 Ferroportin1 (FPN1) Ion_trans PF00520.31 EMR70685.1 - 3.5e-90 301.5 65.8 4.3e-39 134.2 2.2 6.2 4 3 2 6 6 6 5 Ion transport protein ORMDL PF04061.14 EMR70685.1 - 6.8 6.5 11.1 0.27 11.0 2.1 3.4 3 0 0 3 3 3 0 ORMDL family Sec20 PF03908.13 EMR70686.1 - 2.5e-16 59.3 0.5 2.5e-16 59.3 0.5 2.7 4 0 0 4 4 4 1 Sec20 DASH_Dam1 PF08653.10 EMR70686.1 - 0.00035 20.3 5.4 0.0025 17.6 0.1 2.8 3 0 0 3 3 3 2 DASH complex subunit Dam1 DUF4407 PF14362.6 EMR70686.1 - 0.43 9.9 13.3 3.6 6.9 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EMR70686.1 - 4.2 7.9 8.7 2.8e+02 2.0 5.5 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FapA PF03961.13 EMR70686.1 - 7 5.1 7.9 0.29 9.7 1.8 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Perilipin PF03036.16 EMR70686.1 - 9 5.2 13.9 0.75 8.8 7.0 2.0 2 0 0 2 2 2 0 Perilipin family PCRF PF03462.18 EMR70686.1 - 9.6 6.0 9.9 11 5.8 0.5 2.3 2 0 0 2 2 2 0 PCRF domain Git3 PF11710.8 EMR70687.1 - 3.1e-18 66.3 12.1 4.8e-18 65.7 12.1 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EMR70687.1 - 4.5e-07 29.9 0.0 1.4e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EMR70687.1 - 2.4e-05 23.8 8.5 3.6e-05 23.2 8.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 EMR70687.1 - 0.00029 20.1 9.8 0.00046 19.4 9.8 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor adh_short_C2 PF13561.6 EMR70688.1 - 2.1e-57 194.4 0.1 2.4e-57 194.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR70688.1 - 1.4e-44 151.9 0.2 1.9e-44 151.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR70688.1 - 2e-11 44.1 1.7 2.8e-11 43.7 1.7 1.1 1 0 0 1 1 1 1 KR domain DAHP_synth_1 PF00793.20 EMR70690.1 - 1.3e-97 325.9 0.0 1.7e-97 325.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PHD PF00628.29 EMR70691.1 - 2.5e-09 36.9 9.1 5.6e-09 35.7 9.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EMR70691.1 - 0.0075 15.8 5.3 0.015 14.9 5.3 1.5 1 0 0 1 1 1 1 PHD-finger Peptidase_C15 PF01470.17 EMR70692.1 - 4.4e-08 33.5 0.0 1e-07 32.3 0.0 1.6 2 0 0 2 2 2 1 Pyroglutamyl peptidase Dus PF01207.17 EMR70693.1 - 3.5e-46 157.7 0.2 2.2e-45 155.1 0.2 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Furin-like_2 PF15913.5 EMR70694.1 - 0.034 14.3 2.3 0.064 13.4 2.3 1.4 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich Zn_clus PF00172.18 EMR70694.1 - 0.038 14.1 9.6 0.068 13.3 9.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.11 EMR70694.1 - 2.6 6.2 5.8 2.9 6.0 0.0 2.6 3 0 0 3 3 3 0 Rhoptry-associated protein 1 (RAP-1) Oxidored_FMN PF00724.20 EMR70695.1 - 1.1e-65 222.1 0.0 1.7e-62 211.7 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DNA_pol_viral_C PF00336.18 EMR70695.1 - 0.18 11.1 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Acetyltransf_10 PF13673.7 EMR70698.1 - 0.00099 19.1 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR70698.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR70698.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HMG_box PF00505.19 EMR70699.1 - 8.5e-09 35.7 1.1 1.8e-08 34.6 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR70699.1 - 0.00051 20.6 0.4 0.0017 18.9 0.4 1.9 1 0 0 1 1 1 1 HMG-box domain RNA_ligase PF09414.10 EMR70700.1 - 3.2e-30 105.6 0.0 4.9e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 RNA ligase Aldo_ket_red PF00248.21 EMR70701.1 - 1.8e-42 145.6 0.0 2.4e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 EMR70703.1 - 5.6e-26 91.2 0.4 6.6e-26 91.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70703.1 - 7.8e-21 74.7 0.6 9.8e-21 74.4 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70703.1 - 4e-06 26.9 0.1 5.6e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 KR domain MRP_L53 PF10780.9 EMR70704.1 - 1.3e-19 70.1 0.1 1.7e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 SLD5_C PF16922.5 EMR70705.1 - 4.1e-14 52.5 0.0 6.5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EMR70705.1 - 7.2e-07 29.7 0.2 2.2e-06 28.1 0.1 1.8 2 0 0 2 2 2 1 GINS complex protein Abhydrolase_6 PF12697.7 EMR70706.1 - 9.8e-22 78.6 4.7 1.2e-21 78.4 3.9 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR70706.1 - 5e-11 42.7 0.4 5.2e-08 32.8 0.1 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Thioesterase PF00975.20 EMR70706.1 - 3.2e-07 30.7 0.0 5.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EMR70706.1 - 2.4e-06 27.0 0.2 4.2e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MAGE_N PF12440.8 EMR70706.1 - 5.6 7.7 7.9 3.9 8.2 1.9 2.8 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal MgsA_C PF12002.8 EMR70707.1 - 7.3e-59 198.4 0.1 1.6e-58 197.3 0.1 1.6 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EMR70707.1 - 9.9e-24 83.5 0.7 2.1e-23 82.4 0.7 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EMR70707.1 - 1.5e-13 51.3 0.1 3.4e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMR70707.1 - 1.6e-08 34.5 0.0 3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EMR70707.1 - 2.8e-06 27.2 0.2 5.3e-05 23.0 0.1 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 EMR70707.1 - 1.2e-05 25.4 0.0 0.0005 20.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMR70707.1 - 1.2e-05 25.7 1.0 0.011 16.2 0.0 3.2 1 1 2 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 EMR70707.1 - 5.6e-05 22.6 0.1 0.1 12.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EMR70707.1 - 6.3e-05 23.3 0.2 0.00025 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EMR70707.1 - 0.0023 17.2 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 EMR70707.1 - 0.0036 16.5 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EMR70707.1 - 0.0041 17.2 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 EMR70707.1 - 0.0048 16.7 0.0 1.1 9.0 0.0 2.5 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 EMR70707.1 - 0.0063 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EMR70707.1 - 0.011 16.1 0.4 0.052 13.9 0.4 2.2 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EMR70707.1 - 0.019 15.0 0.5 0.69 9.9 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit CPT PF07931.12 EMR70707.1 - 0.04 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.22 EMR70707.1 - 0.046 13.8 0.1 0.084 13.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate kinase TRAF6_Z2 PF18048.1 EMR70707.1 - 0.062 13.4 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 AAA_24 PF13479.6 EMR70707.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMR70707.1 - 0.096 12.4 0.1 0.42 10.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EMR70707.1 - 0.12 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_23 PF13476.6 EMR70707.1 - 0.16 12.5 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EMR70707.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NB-ARC PF00931.22 EMR70707.1 - 0.2 10.8 0.0 0.4 9.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Bromodomain PF00439.25 EMR70708.1 - 6.9e-33 112.6 0.0 5.3e-16 58.5 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EMR70708.1 - 4.7e-13 49.1 0.6 1.3e-12 47.7 0.6 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation p450 PF00067.22 EMR70709.1 - 1.8e-54 185.2 0.0 2.6e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TetR_C_9 PF14514.6 EMR70709.1 - 0.11 12.7 0.5 1.7 8.7 0.0 3.0 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain ADH_zinc_N PF00107.26 EMR70710.1 - 2.7e-20 72.7 0.9 2.7e-20 72.7 0.9 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR70710.1 - 5e-20 71.4 3.2 1.1e-19 70.3 3.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMR70710.1 - 0.0019 19.3 2.0 0.0037 18.3 2.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EMR70710.1 - 0.029 15.1 0.6 0.17 12.6 0.5 2.2 1 1 1 2 2 2 0 Methyltransferase domain Nop PF01798.18 EMR70711.1 - 5.2e-79 264.9 0.1 5.2e-79 264.9 0.1 3.0 4 0 0 4 4 4 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EMR70711.1 - 4e-18 65.6 0.3 4e-18 65.6 0.3 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Gmx_para_CXXCG PF09535.10 EMR70711.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) PRiA4_ORF3 PF07929.11 EMR70712.1 - 5.5e-28 97.8 0.0 1.4e-27 96.5 0.0 1.6 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 EMR70712.1 - 3.6e-10 39.7 11.4 9.1e-10 38.5 11.4 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EMR70712.1 - 6.1 7.2 12.8 2.1 8.7 8.7 2.4 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Utp12 PF04003.12 EMR70713.1 - 1.5e-24 86.3 0.3 2.1e-24 85.9 0.3 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family SDA1 PF05285.12 EMR70713.1 - 0.4 10.0 32.8 0.34 10.3 21.8 2.1 2 0 0 2 2 2 0 SDA1 vATP-synt_AC39 PF01992.16 EMR70714.1 - 1.8e-108 363.0 0.0 2.1e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 EMR70715.1 - 2.4e-20 72.5 0.5 5.5e-19 68.2 0.2 2.7 2 0 0 2 2 2 1 Ribosomal protein S15 Androgen_recep PF02166.16 EMR70715.1 - 4.4 6.0 11.9 0.89 8.3 7.5 1.8 2 0 0 2 2 2 0 Androgen receptor ANAPC_CDC26 PF10471.9 EMR70715.1 - 6.4 7.7 18.2 12 6.8 6.7 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Ank_2 PF12796.7 EMR70716.1 - 1.7e-06 28.5 0.0 0.037 14.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR70716.1 - 0.00043 20.5 0.2 2.5 8.9 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EMR70716.1 - 0.0018 18.6 1.0 9.3 6.9 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EMR70716.1 - 0.03 14.9 0.1 44 4.8 0.0 4.4 5 0 0 5 5 5 0 Ankyrin repeats (many copies) F-box-like PF12937.7 EMR70716.1 - 0.09 12.7 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 F-box-like Ribosomal_S2 PF00318.20 EMR70717.1 - 8.6e-26 90.5 0.2 7.8e-14 51.4 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EMR70717.1 - 4.1e-06 28.1 10.4 7.3e-06 27.3 10.4 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus RBFA PF02033.18 EMR70717.1 - 0.076 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosome-binding factor A p450 PF00067.22 EMR70718.1 - 4e-27 95.1 0.0 5.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RasGEF PF00617.19 EMR70719.1 - 2.1e-48 164.9 0.1 3.2e-48 164.3 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain Glyco_hydro_3_C PF01915.22 EMR70721.1 - 1.6e-46 158.8 0.0 3e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EMR70721.1 - 3.7e-29 100.6 0.3 7.2e-29 99.7 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 EMR70721.1 - 7.2e-26 91.3 0.1 9.6e-17 61.3 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Rpp20 PF12328.8 EMR70723.1 - 3.8e-27 94.9 0.6 4.8e-27 94.6 0.6 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EMR70723.1 - 5.6e-11 42.1 0.0 1.4e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Alba Cutinase PF01083.22 EMR70724.1 - 3.5e-22 79.2 0.0 5.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 EMR70724.1 - 0.022 14.4 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 EMR70724.1 - 0.045 13.3 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Lipase_3 PF01764.25 EMR70724.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 EMR70724.1 - 0.23 10.9 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DAO PF01266.24 EMR70725.1 - 3.7e-27 95.8 6.4 1.8e-26 93.6 6.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR70725.1 - 1.8e-06 28.0 1.0 0.0036 17.3 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 EMR70725.1 - 0.00023 20.4 0.2 0.0087 15.2 0.0 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EMR70725.1 - 0.00026 20.3 0.0 0.0019 17.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR70725.1 - 0.0053 16.9 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR70725.1 - 0.084 11.9 0.3 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EMR70725.1 - 0.17 11.1 0.1 8.7 5.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR70725.1 - 0.32 9.8 1.5 12 4.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Rogdi_lz PF10259.9 EMR70726.1 - 2.7e-84 282.8 0.0 3.9e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Suf PF05843.14 EMR70726.1 - 0.46 10.4 2.3 0.79 9.7 2.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MFS_1 PF07690.16 EMR70727.1 - 5e-11 42.1 31.3 4.2e-10 39.1 30.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily PCI PF01399.27 EMR70728.1 - 9.7e-21 74.3 0.0 3.2e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EMR70728.1 - 1.8e-16 59.9 1.7 4.5e-16 58.6 1.7 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF2935 PF11155.8 EMR70728.1 - 0.097 13.0 0.2 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Ribosomal_60s PF00428.19 EMR70728.1 - 0.86 10.2 0.0 0.86 10.2 0.0 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein NIPSNAP PF07978.13 EMR70729.1 - 4.4e-41 139.3 5.3 8.4e-30 103.0 0.2 2.7 3 0 0 3 3 3 2 NIPSNAP AAA_28 PF13521.6 EMR70729.1 - 0.036 14.3 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain NmrA PF05368.13 EMR70730.1 - 1e-15 57.9 0.0 1.4e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR70730.1 - 6.6e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR70730.1 - 1.9e-07 30.8 0.0 6.4e-06 25.8 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR70730.1 - 0.041 13.3 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 EMR70730.1 - 0.17 12.0 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FSH1 PF03959.13 EMR70731.1 - 1.9e-55 187.8 0.0 2.6e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EMR70731.1 - 0.021 14.1 0.0 0.2 10.9 0.0 2.3 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EMR70731.1 - 0.11 12.2 0.1 1.9 8.2 0.1 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2631 PF10939.8 EMR70731.1 - 0.52 10.2 3.6 0.15 11.9 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) p450 PF00067.22 EMR70732.1 - 3.2e-51 174.5 0.0 5.4e-51 173.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 F-box PF00646.33 EMR70733.1 - 0.0029 17.4 0.6 0.0069 16.2 0.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMR70733.1 - 0.0076 16.1 0.4 0.02 14.8 0.2 1.8 2 0 0 2 2 2 1 F-box-like DUF3944 PF13099.6 EMR70734.1 - 0.15 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) zf-DBF PF07535.12 EMR70734.1 - 0.2 11.8 2.3 0.82 9.8 0.2 2.8 2 1 0 2 2 2 0 DBF zinc finger Occludin_ELL PF07303.13 EMR70734.1 - 1 10.1 10.0 3 8.6 10.0 1.9 1 1 0 1 1 1 0 Occludin homology domain peroxidase PF00141.23 EMR70735.1 - 5e-82 275.0 0.0 3.4e-44 151.3 0.0 2.3 2 0 0 2 2 2 2 Peroxidase GFA PF04828.14 EMR70737.1 - 1e-11 45.0 0.3 1.5e-11 44.4 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 EMR70738.1 - 7.3e-34 117.2 18.5 7.3e-34 117.2 18.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 EMR70738.1 - 0.001 17.9 6.8 0.002 17.0 6.8 1.5 1 1 0 1 1 1 1 LacY proton/sugar symporter Acetyltransf_1 PF00583.25 EMR70739.1 - 3.5e-11 43.4 0.0 5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR70739.1 - 1.1e-09 38.3 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR70739.1 - 5.2e-07 30.0 0.0 7.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMR70739.1 - 0.00089 19.4 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR70739.1 - 0.029 14.4 0.1 0.12 12.5 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M19 PF01244.21 EMR70740.1 - 5.5e-69 232.8 0.0 6.6e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Sugar_tr PF00083.24 EMR70741.1 - 1.8e-83 280.9 16.9 2.2e-83 280.7 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR70741.1 - 4.2e-27 95.0 17.4 6.7e-27 94.3 17.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EMR70741.1 - 6.6e-06 24.9 9.4 4.8e-05 22.1 1.4 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EMR70741.1 - 0.0018 16.8 2.8 0.0055 15.2 0.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 EMR70741.1 - 1.1 8.0 11.6 0.079 11.8 2.4 2.3 2 0 0 2 2 2 0 POT family Glyco_hydro_16 PF00722.21 EMR70742.1 - 1.2e-09 37.9 0.1 1.9e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Tannase PF07519.11 EMR70743.1 - 3.6e-83 280.0 0.1 1.9e-81 274.3 0.1 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EMR70743.1 - 3.1e-07 30.1 0.3 0.0045 16.5 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EMR70743.1 - 0.0034 16.7 0.0 0.085 12.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR70743.1 - 0.05 13.2 0.3 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EMR70743.1 - 0.057 13.1 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 EMR70744.1 - 5.2e-29 101.3 0.1 6.3e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Sulfatase PF00884.23 EMR70744.1 - 0.041 13.3 0.0 0.052 12.9 0.0 1.3 1 1 0 1 1 1 0 Sulfatase Peptidase_S9 PF00326.21 EMR70744.1 - 0.066 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PAP2 PF01569.21 EMR70745.1 - 2.8e-27 95.1 0.4 2.8e-27 95.1 0.4 2.2 2 0 0 2 2 2 1 PAP2 superfamily YhhN PF07947.14 EMR70745.1 - 0.047 13.3 2.4 0.51 9.9 2.4 2.2 1 1 0 1 1 1 0 YhhN family Saf_2TM PF18303.1 EMR70745.1 - 0.22 11.1 1.0 1.1 8.9 0.5 2.1 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain FF PF01846.19 EMR70747.1 - 2.3e-09 37.3 4.1 1.6e-08 34.6 0.1 2.8 2 0 0 2 2 2 1 FF domain WW PF00397.26 EMR70747.1 - 4.4e-09 36.3 1.4 4.4e-09 36.3 1.4 2.7 2 0 0 2 2 2 1 WW domain Amidoligase_2 PF12224.8 EMR70748.1 - 1.5e-13 51.0 0.0 4.7e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Dynamin_N PF00350.23 EMR70749.1 - 1.2e-22 80.7 0.0 3.2e-21 76.1 0.0 2.5 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EMR70749.1 - 0.0017 17.7 0.7 0.0045 16.3 0.4 1.9 2 1 0 2 2 2 1 Dynamin central region GED PF02212.18 EMR70749.1 - 0.0078 16.3 0.7 0.028 14.6 0.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EMR70749.1 - 0.029 14.5 0.0 0.44 10.6 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EMR70749.1 - 0.082 13.4 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Beta_helix PF13229.6 EMR70751.1 - 0.062 13.1 21.3 2.8 7.8 21.3 2.6 1 1 0 1 1 1 0 Right handed beta helix region Binary_toxB PF03495.14 EMR70751.1 - 0.13 12.5 0.7 0.46 10.7 0.7 2.0 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Abhydrolase_1 PF00561.20 EMR70752.1 - 5.9e-15 55.6 0.0 2.4e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR70752.1 - 2.1e-12 48.1 0.0 2.8e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR70752.1 - 2.1e-05 23.9 0.0 3.9e-05 23.0 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMR70752.1 - 0.037 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 EMR70752.1 - 0.17 11.4 0.0 0.71 9.4 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family FTA2 PF13095.6 EMR70753.1 - 5e-35 121.1 0.0 7.2e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Amidohydro_1 PF01979.20 EMR70754.1 - 1.9e-17 63.6 0.2 7.1e-16 58.4 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR70754.1 - 1.7e-15 57.5 1.1 1.5e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family CH PF00307.31 EMR70755.1 - 6.5e-47 158.2 0.1 5.1e-22 78.1 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EMR70755.1 - 3.3e-24 84.8 0.2 1.7e-23 82.5 0.0 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EMR70755.1 - 3.1e-11 43.0 0.7 2.4e-05 24.1 0.0 3.4 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.6 EMR70755.1 - 0.001 19.5 2.6 0.0025 18.2 1.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EMR70755.1 - 0.0011 18.7 0.1 0.008 16.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain CH_2 PF06294.11 EMR70755.1 - 0.0014 18.7 0.0 0.082 13.0 0.0 3.3 3 0 0 3 3 3 1 CH-like domain in sperm protein EF-hand_8 PF13833.6 EMR70755.1 - 0.033 14.0 0.6 0.37 10.7 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain pair SF-assemblin PF06705.11 EMR70755.1 - 0.85 8.9 4.5 7.2 5.9 0.5 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin GARS_A PF01071.19 EMR70756.1 - 1.7e-84 282.4 0.0 2.7e-84 281.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EMR70756.1 - 8.9e-33 112.9 0.0 2.5e-32 111.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EMR70756.1 - 2.9e-30 105.5 0.0 8.9e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EMR70756.1 - 2.3e-25 88.7 1.6 4.2e-25 87.8 0.7 2.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EMR70756.1 - 6.3e-14 52.4 4.8 6.3e-14 52.4 4.8 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 EMR70756.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EMR70756.1 - 0.00064 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EMR70756.1 - 0.00092 19.3 0.0 0.0033 17.5 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EMR70756.1 - 0.037 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 EMR70756.1 - 0.042 13.1 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RimK PF08443.11 EMR70756.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 EMR70756.1 - 0.14 11.7 0.2 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain Lipase_3 PF01764.25 EMR70757.1 - 0.00018 21.4 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) HLH PF00010.26 EMR70758.1 - 2.2e-12 46.8 0.3 6.4e-12 45.2 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.12 EMR70758.1 - 0.22 11.1 0.1 0.33 10.6 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein GIT1_C PF12205.8 EMR70758.1 - 0.38 10.9 6.8 0.22 11.6 2.3 2.4 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF2431 PF10354.9 EMR70759.1 - 1.5e-68 230.4 0.0 1.8e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) DUF4570 PF15134.6 EMR70760.1 - 0.034 14.1 0.5 0.067 13.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) PP1c_bdg PF10488.9 EMR70760.1 - 0.036 13.6 0.4 0.057 12.9 0.4 1.3 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Ntox6 PF15544.6 EMR70760.1 - 0.051 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 6 NDUF_B12 PF08122.12 EMR70761.1 - 1.2e-23 82.9 0.7 1.7e-23 82.4 0.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family VPS9 PF02204.18 EMR70762.1 - 4.8e-26 91.0 0.0 7.6e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CLTH PF10607.9 EMR70763.1 - 2.8e-33 114.9 0.0 4.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain TFIIA PF03153.13 EMR70763.1 - 0.0017 18.5 11.8 0.0022 18.1 11.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EMR70763.1 - 0.015 13.7 7.2 0.017 13.5 7.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IMUP PF15761.5 EMR70763.1 - 0.037 14.7 11.6 0.2 12.4 0.0 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein RR_TM4-6 PF06459.12 EMR70763.1 - 0.1 12.4 3.8 0.18 11.6 3.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LisH PF08513.11 EMR70763.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 LisH SOG2 PF10428.9 EMR70763.1 - 0.23 10.6 15.3 0.39 9.8 15.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SMYLE_N PF18615.1 EMR70763.1 - 0.84 9.1 6.6 0.65 9.5 4.7 1.7 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Menin PF05053.13 EMR70763.1 - 0.88 7.8 4.3 1.4 7.2 4.3 1.2 1 0 0 1 1 1 0 Menin Suf PF05843.14 EMR70763.1 - 1.1 9.2 11.1 0.18 11.8 7.0 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SR-25 PF10500.9 EMR70763.1 - 1.3 8.6 14.9 5 6.7 7.6 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Endostatin PF06482.11 EMR70763.1 - 3 7.2 11.0 5.7 6.3 11.0 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF5427 PF10310.9 EMR70763.1 - 6.6 5.6 14.4 14 4.5 14.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Dicty_REP PF05086.12 EMR70763.1 - 6.9 4.5 8.2 9.8 4.0 8.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Golgin_A5 PF09787.9 EMR70764.1 - 0.0097 15.4 5.4 0.017 14.6 5.4 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 Spc7 PF08317.11 EMR70764.1 - 0.19 10.6 5.8 0.31 9.9 5.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1682 PF07946.14 EMR70764.1 - 2.4 7.3 9.2 3.5 6.7 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ZapB PF06005.12 EMR70764.1 - 7.5 7.1 0.0 7.5 7.1 0.0 2.9 3 1 0 3 3 3 0 Cell division protein ZapB CAF1 PF04857.20 EMR70765.1 - 1.3e-11 44.2 0.1 4.1e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease ThiF PF00899.21 EMR70766.1 - 1.7e-30 106.2 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family eIF-5_eIF-2B PF01873.17 EMR70767.1 - 1e-39 135.0 0.0 2e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EMR70767.1 - 2.9e-24 85.0 1.6 6.8e-24 83.8 0.6 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon FGF-BP1 PF06473.12 EMR70767.1 - 0.035 14.0 2.1 0.055 13.3 2.1 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF4519 PF15012.6 EMR70767.1 - 9 6.6 6.6 20 5.5 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) eIF-6 PF01912.18 EMR70769.1 - 1.9e-80 268.9 0.9 2.5e-80 268.5 0.9 1.2 1 0 0 1 1 1 1 eIF-6 family PUF PF00806.19 EMR70771.1 - 7.4e-55 179.7 11.1 2.2e-08 33.3 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EMR70771.1 - 2.1e-07 31.4 4.4 0.38 11.1 0.0 4.4 1 1 2 3 3 3 2 CPL (NUC119) domain Rif1_N PF12231.8 EMR70771.1 - 0.092 11.7 3.7 0.083 11.9 1.6 1.8 2 0 0 2 2 2 0 Rap1-interacting factor 1 N terminal IZUMO PF15005.6 EMR70771.1 - 0.14 12.7 2.4 0.36 11.3 1.4 2.0 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated MgtE_N PF03448.17 EMR70771.1 - 0.15 12.6 0.6 2.7 8.7 0.1 2.7 2 2 1 3 3 3 0 MgtE intracellular N domain LOB PF03195.14 EMR70771.1 - 0.22 12.1 1.7 4.7 7.9 0.6 2.7 2 1 1 3 3 3 0 Lateral organ boundaries (LOB) domain CoaE PF01121.20 EMR70772.1 - 3.2e-41 141.0 0.0 1.1e-40 139.3 0.0 1.7 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 EMR70772.1 - 0.0031 17.7 0.0 0.026 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMR70772.1 - 0.12 12.9 0.1 1.9 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain LapA_dom PF06305.11 EMR70773.1 - 0.099 12.5 0.8 0.15 11.9 0.8 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain THUMP PF02926.17 EMR70774.1 - 1.8e-09 37.8 0.6 2.1e-08 34.4 0.6 2.1 1 1 0 1 1 1 1 THUMP domain Myc_N PF01056.18 EMR70775.1 - 0.22 11.4 4.8 0.33 10.8 4.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 EMR70775.1 - 3.1 7.0 4.2 5.2 6.3 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein HSF_DNA-bind PF00447.17 EMR70776.1 - 2.4e-28 98.6 1.3 5.3e-28 97.5 1.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EMR70776.1 - 2.6e-22 79.1 0.1 5.1e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Mod_r PF07200.13 EMR70776.1 - 0.016 15.3 4.0 0.026 14.6 4.0 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 EMR70776.1 - 0.052 14.2 2.7 0.11 13.1 2.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA CortBP2 PF09727.9 EMR70776.1 - 0.089 12.7 2.5 0.15 11.9 2.5 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 V_ATPase_I PF01496.19 EMR70776.1 - 0.36 8.7 2.8 0.46 8.4 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 EMR70776.1 - 0.78 10.2 7.6 1.5 9.2 7.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.12 EMR70776.1 - 8.1 7.1 8.7 17 6.2 1.5 2.7 1 1 1 2 2 2 0 SlyX Dynamin_N PF00350.23 EMR70777.1 - 1.2e-43 149.0 0.0 2.2e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family PQ-loop PF04193.14 EMR70777.1 - 1.8e-32 110.9 12.0 3.9e-16 58.6 5.0 2.6 2 0 0 2 2 2 2 PQ loop repeat Dynamin_M PF01031.20 EMR70777.1 - 1e-13 51.2 0.0 2.3e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EMR70777.1 - 2.3e-05 24.4 0.0 0.00038 20.5 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EMR70777.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMR70777.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 EMR70777.1 - 0.29 11.5 3.5 0.3 11.4 0.0 2.6 3 1 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 EMR70778.1 - 4e-47 160.2 0.0 6.4e-22 78.6 0.0 3.2 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EMR70778.1 - 5.8e-19 67.9 7.0 5.8e-19 67.9 7.0 4.1 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 EMR70778.1 - 7e-17 62.2 3.4 0.00038 20.4 0.0 4.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMR70778.1 - 6.7e-11 42.0 0.9 0.0071 15.8 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EMR70778.1 - 4.3e-07 30.0 0.3 0.011 15.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EMR70778.1 - 2.1e-06 28.3 0.5 0.074 13.6 0.0 3.4 4 1 0 4 4 2 2 AAA domain RsgA_GTPase PF03193.16 EMR70778.1 - 2.3e-06 27.6 0.9 0.05 13.5 0.0 2.9 2 1 1 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 EMR70778.1 - 3e-06 26.9 0.1 0.06 13.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EMR70778.1 - 1.2e-05 25.8 3.4 0.019 15.3 0.2 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 EMR70778.1 - 1.2e-05 25.1 0.2 0.003 17.3 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMR70778.1 - 4.9e-05 23.9 0.5 0.0044 17.5 0.1 4.6 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.6 EMR70778.1 - 6.2e-05 23.3 0.1 0.44 10.8 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 EMR70778.1 - 0.00013 22.4 0.0 0.38 11.2 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EMR70778.1 - 0.00013 22.2 3.0 0.31 11.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EMR70778.1 - 0.00067 19.6 0.1 0.85 9.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 EMR70778.1 - 0.0014 18.6 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EMR70778.1 - 0.0015 17.5 0.3 0.82 8.6 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EMR70778.1 - 0.0028 18.0 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EMR70778.1 - 0.0031 17.3 1.8 1.2 8.8 0.3 2.9 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 EMR70778.1 - 0.0033 17.1 0.5 0.96 9.0 0.5 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EMR70778.1 - 0.0033 17.6 0.0 3.1 8.0 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EMR70778.1 - 0.0039 17.5 6.2 0.11 12.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 EMR70778.1 - 0.0053 16.7 0.1 0.64 9.9 0.1 2.7 3 0 0 3 3 2 1 NTPase MobB PF03205.14 EMR70778.1 - 0.006 16.5 0.1 0.2 11.6 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 EMR70778.1 - 0.0081 15.9 14.2 0.08 12.6 0.2 4.3 5 1 0 6 6 6 2 AAA ATPase domain AAA_7 PF12775.7 EMR70778.1 - 0.0087 15.6 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 EMR70778.1 - 0.025 13.8 0.1 4.2 6.5 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 EMR70778.1 - 0.026 14.5 0.3 7.3 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 EMR70778.1 - 0.027 14.1 3.3 4.4 6.8 0.0 3.4 4 0 0 4 4 2 0 AAA domain ATP-synt_ab PF00006.25 EMR70778.1 - 0.028 14.1 0.1 2 8.0 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 EMR70778.1 - 0.05 13.5 0.2 5 7.0 0.0 3.1 2 1 0 3 3 3 0 Rad17 P-loop domain TsaE PF02367.17 EMR70778.1 - 0.081 12.9 0.1 8.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EMR70778.1 - 0.2 12.1 3.8 27 5.2 0.3 3.6 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 EMR70778.1 - 0.25 11.0 4.9 1.9 8.1 0.0 3.4 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 EMR70778.1 - 0.25 11.4 9.2 4.5 7.3 0.9 4.6 3 1 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 EMR70778.1 - 0.45 10.2 1.7 31 4.2 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Flavoprotein PF02441.19 EMR70780.1 - 3.9e-19 69.0 0.1 5.8e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Flavoprotein WD40 PF00400.32 EMR70781.1 - 3.2e-24 84.7 24.8 1.3e-05 25.8 0.1 7.2 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR70781.1 - 3.8e-15 56.0 4.7 1.2e-07 31.9 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EMR70781.1 - 2.1e-06 27.8 8.5 0.0028 17.6 0.2 3.3 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Big_2 PF02368.18 EMR70781.1 - 0.007 16.2 0.4 0.022 14.6 0.4 1.8 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 2) bZIP_2 PF07716.15 EMR70782.1 - 7e-07 29.2 6.6 1.3e-06 28.4 6.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EMR70782.1 - 0.00023 21.2 6.4 0.00048 20.2 6.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor TTKRSYEDQ PF10212.9 EMR70782.1 - 0.0036 16.4 0.2 0.0049 15.9 0.2 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein GSDH PF07995.11 EMR70784.1 - 0.00059 19.2 0.2 0.0093 15.3 0.0 2.7 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 EMR70784.1 - 0.0079 15.8 0.1 0.16 11.6 0.0 2.4 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 EMR70784.1 - 0.0089 16.0 0.0 5.2 7.1 0.0 2.8 3 0 0 3 3 3 2 Beta-propeller repeat NHL PF01436.21 EMR70784.1 - 0.053 13.6 0.0 26 5.1 0.0 3.8 4 0 0 4 4 4 0 NHL repeat Methyltransf_1N PF02870.15 EMR70784.1 - 0.075 13.8 0.0 0.15 12.9 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Tex_N PF09371.10 EMR70786.1 - 0.052 13.2 0.0 4.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Membrane_bind PF14564.6 EMR70787.1 - 3.1e-21 75.9 0.1 1.2e-19 70.8 0.0 2.4 1 1 1 2 2 2 1 Membrane binding Crystall_3 PF08964.10 EMR70787.1 - 2.6e-16 59.5 0.0 4.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Beta/Gamma crystallin Syncollin PF15138.6 EMR70787.1 - 0.0029 17.8 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 1 Syncollin adh_short PF00106.25 EMR70789.1 - 0.0016 17.9 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR70789.1 - 0.038 13.9 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 KR domain FTA2 PF13095.6 EMR70790.1 - 1.1e-75 254.0 0.0 1.5e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 SYF2 PF08231.12 EMR70791.1 - 7e-53 179.3 9.8 7e-53 179.3 9.8 2.1 2 1 0 2 2 2 1 SYF2 splicing factor FANCA_interact PF15751.5 EMR70791.1 - 0.073 13.6 2.0 0.16 12.4 2.0 1.6 1 0 0 1 1 1 0 FAAP20 FANCA interaction domain 4HBT_3 PF13622.6 EMR70792.1 - 1.6e-10 41.7 3.4 3.4e-08 34.1 0.4 2.1 1 1 1 2 2 2 2 Thioesterase-like superfamily GST_N PF02798.20 EMR70793.1 - 1.1e-13 51.3 0.0 3.3e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR70793.1 - 6.1e-12 45.6 0.0 9.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR70793.1 - 1.9e-10 41.0 0.0 4.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR70793.1 - 3e-10 40.2 0.0 5.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR70793.1 - 8.2e-09 35.6 0.0 2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR70793.1 - 8.8e-08 32.1 0.2 1.7e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMR70793.1 - 0.0031 18.1 0.0 0.43 11.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF4301 PF14134.6 EMR70793.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) Sugar_tr PF00083.24 EMR70797.1 - 6.1e-47 160.5 1.3 7.5e-47 160.2 1.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR70797.1 - 3.3e-22 78.9 6.8 4.3e-22 78.5 6.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR70797.1 - 0.0018 17.2 0.5 0.048 12.5 0.1 2.2 1 1 1 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 EMR70797.1 - 0.0024 16.3 0.1 0.0034 15.9 0.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 EMR70797.1 - 0.0068 15.0 2.8 0.0088 14.6 2.8 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 EMR70797.1 - 0.012 14.1 0.4 0.015 13.8 0.4 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) FAD-oxidase_C PF02913.19 EMR70798.1 - 3.4e-65 220.2 0.3 1.2e-64 218.4 0.2 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMR70798.1 - 1.1e-20 73.8 0.0 3.6e-20 72.1 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 EMR70798.1 - 0.079 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Peptidase_S9 PF00326.21 EMR70799.1 - 7.9e-46 156.2 0.0 9e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 EMR70799.1 - 0.0034 16.6 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) Trypsin PF00089.26 EMR70800.1 - 3.1e-09 37.0 0.0 6.1e-09 36.0 0.0 1.3 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EMR70800.1 - 1.3e-05 26.1 0.0 2.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Pur_ac_phosph_N PF16656.5 EMR70800.1 - 0.039 14.5 0.6 0.32 11.6 0.0 2.2 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Aspzincin_M35 PF14521.6 EMR70801.1 - 7.6e-26 91.4 0.8 1.3e-25 90.6 0.8 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EMR70801.1 - 0.021 14.4 0.7 0.027 14.0 0.2 1.5 2 0 0 2 2 2 0 Putative peptidase family Dioxygenase_C PF00775.21 EMR70803.1 - 1.1e-07 31.5 0.1 2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase Beta_propel PF09826.9 EMR70804.1 - 0.011 14.7 0.1 0.017 14.0 0.1 1.3 1 0 0 1 1 1 0 Beta propeller domain Aa_trans PF01490.18 EMR70805.1 - 1.8e-32 112.5 30.8 2.1e-32 112.3 30.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF872 PF05915.12 EMR70805.1 - 0.019 15.1 2.1 2.3 8.4 0.5 3.3 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Pannexin_like PF12534.8 EMR70805.1 - 0.2 10.7 0.8 0.35 9.9 0.8 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 SLATT_1 PF18181.1 EMR70805.1 - 4.6 7.2 9.3 14 5.7 0.0 3.0 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 CorA PF01544.18 EMR70806.1 - 1.3e-21 77.2 11.2 4.2e-15 55.8 3.3 3.1 2 1 1 3 3 3 3 CorA-like Mg2+ transporter protein AARP2CN PF08142.12 EMR70806.1 - 0.0027 17.7 0.1 0.017 15.2 0.1 2.2 1 1 0 1 1 1 1 AARP2CN (NUC121) domain MDM10 PF12519.8 EMR70807.1 - 7.3e-172 572.4 0.0 8.3e-172 572.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EMR70807.1 - 0.15 11.5 0.1 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic porin FAD_binding_4 PF01565.23 EMR70808.1 - 0.00034 20.4 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EMR70808.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin Polysacc_deac_1 PF01522.21 EMR70810.1 - 2.5e-18 66.2 0.0 5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMR70810.1 - 1e-05 25.3 0.1 2.2e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 EMR70810.1 - 0.015 13.7 0.0 0.021 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Peroxidase_2 PF01328.17 EMR70810.1 - 0.16 12.5 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 Peroxidase, family 2 Zip PF02535.22 EMR70811.1 - 3.3e-68 230.4 8.0 3.8e-68 230.2 8.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter FA_desaturase PF00487.24 EMR70811.1 - 4.7 7.0 8.2 0.39 10.5 2.4 2.2 3 1 0 3 3 3 0 Fatty acid desaturase Rad9 PF04139.13 EMR70812.1 - 9.4e-30 103.9 0.7 8.1e-22 77.9 0.0 2.1 1 1 1 2 2 2 2 Rad9 Amino_oxidase PF01593.24 EMR70814.1 - 7.6e-60 203.5 1.3 1.6e-58 199.1 1.3 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR70814.1 - 1.3e-10 41.3 0.3 2.7e-10 40.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR70814.1 - 0.00087 18.6 0.2 0.0017 17.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMR70814.1 - 0.0037 16.6 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EMR70814.1 - 0.0052 15.9 0.0 0.0098 15.0 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 EMR70814.1 - 0.0052 16.4 0.5 0.04 13.5 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMR70814.1 - 0.013 14.8 0.3 0.045 13.0 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 EMR70814.1 - 0.023 14.8 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 EMR70814.1 - 0.027 13.8 0.6 0.045 13.1 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR70814.1 - 0.033 13.5 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR70814.1 - 0.052 12.6 0.2 0.075 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EMR70814.1 - 0.071 13.7 0.3 0.22 12.1 0.1 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR70814.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EMR70814.1 - 0.12 11.1 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EMR70814.1 - 0.15 12.0 0.1 0.8 9.7 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding AA_permease PF00324.21 EMR70815.1 - 2.1e-138 461.9 38.3 2.4e-138 461.7 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR70815.1 - 9.2e-43 146.6 40.8 1.2e-42 146.2 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 EMR70815.1 - 0.053 12.3 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Alk_phosphatase PF00245.20 EMR70816.1 - 1.2e-101 340.7 0.0 1.7e-101 340.2 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EMR70816.1 - 1.4e-06 27.9 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily PDH PF02153.17 EMR70818.1 - 1.3e-16 60.4 0.1 1.8e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Ribosomal_S19e PF01090.19 EMR70820.1 - 9.9e-58 193.7 0.1 1.1e-57 193.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e SCP1201-deam PF14428.6 EMR70821.1 - 0.03 14.2 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 SCP1.201-like deaminase AP3D1 PF06375.11 EMR70821.1 - 0.055 13.7 3.0 0.099 12.9 3.0 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 GST_C_3 PF14497.6 EMR70822.1 - 8.6e-26 90.0 0.3 1e-24 86.6 0.3 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR70822.1 - 4.5e-05 23.6 0.2 0.0014 18.8 0.0 2.2 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR70822.1 - 0.023 14.7 0.1 0.085 12.9 0.1 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Lipase_GDSL_2 PF13472.6 EMR70823.1 - 2.6e-16 60.5 1.5 3.5e-16 60.1 1.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR70823.1 - 7.1e-08 32.7 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EMR70823.1 - 0.014 15.6 0.0 0.51 10.5 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 EMR70824.1 - 1.3e-19 70.4 48.3 2.8e-11 43.0 14.1 3.2 2 1 2 4 4 4 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR70824.1 - 1.1e-06 27.3 12.4 1.1e-06 27.3 12.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1418 PF07214.12 EMR70824.1 - 0.069 13.0 2.9 0.3 11.0 2.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Pyr_redox_2 PF07992.14 EMR70825.1 - 2.3e-11 43.5 0.0 3.7e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR70825.1 - 9.4e-06 24.6 0.0 0.0034 16.1 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 EMR70825.1 - 1.6e-05 24.4 0.0 0.15 11.3 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR70825.1 - 0.00041 19.6 0.0 0.00067 18.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EMR70825.1 - 0.00095 18.5 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMR70825.1 - 0.0016 17.7 0.1 0.0027 17.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EMR70825.1 - 0.0036 16.7 0.1 0.0076 15.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR70825.1 - 0.0074 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR70825.1 - 0.0081 15.8 1.1 0.047 13.3 0.5 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR70825.1 - 0.0086 16.1 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 EMR70825.1 - 0.017 14.2 0.0 0.19 10.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Methyltransf_11 PF08241.12 EMR70826.1 - 1.4e-11 44.9 0.0 2.1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR70826.1 - 3.1e-10 40.6 0.0 4.1e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR70826.1 - 4.2e-09 36.1 0.0 4.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EMR70826.1 - 0.00075 19.4 0.0 0.0009 19.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR70826.1 - 0.018 15.8 0.0 0.025 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 EMR70827.1 - 2.6e-06 26.6 8.3 2.6e-06 26.6 8.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EMR70828.1 - 2.3e-25 89.3 0.1 2.6e-25 89.0 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EMR70829.1 - 7.7e-21 74.4 5.3 1.1e-20 73.9 5.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70829.1 - 3.2e-20 72.7 7.7 4.9e-20 72.1 7.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70829.1 - 1.6e-08 34.6 1.8 2.1e-08 34.3 1.8 1.1 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 EMR70829.1 - 0.078 13.7 0.6 0.13 12.9 0.6 1.6 1 1 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 EMR70830.1 - 4.2e-51 174.1 0.0 5e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_C_2 PF13410.6 EMR70831.1 - 8.1e-06 25.8 0.1 1.7e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR70831.1 - 0.0043 17.3 0.0 0.0073 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SPA PF08616.10 EMR70833.1 - 2.1e-38 130.8 0.0 3.3e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 EMR70833.1 - 0.0024 17.5 0.0 0.0094 15.6 0.0 1.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 EMR70833.1 - 0.031 13.0 0.0 0.7 8.5 0.0 2.1 1 1 1 2 2 2 0 Transport protein Avl9 Afi1 PF07792.12 EMR70833.1 - 0.034 14.6 0.1 0.057 13.9 0.1 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2554 PF10829.8 EMR70833.1 - 0.063 13.7 0.1 3.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) MFS_1 PF07690.16 EMR70834.1 - 1.3e-25 90.1 21.5 1.3e-25 90.1 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 EMR70834.1 - 0.0025 18.5 0.2 0.2 12.3 0.0 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.15 EMR70834.1 - 0.077 13.6 0.0 0.27 11.9 0.0 1.9 2 0 0 2 2 2 0 Ctr copper transporter family Phage_holin_4_2 PF04020.13 EMR70834.1 - 1.7 9.4 7.6 0.089 13.5 0.8 2.4 3 0 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV Sugar_tr PF00083.24 EMR70834.1 - 2.1 7.1 22.8 0.028 13.3 6.6 3.0 2 1 1 3 3 3 0 Sugar (and other) transporter adh_short PF00106.25 EMR70835.1 - 2.8e-18 66.1 0.0 4.2e-15 55.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70835.1 - 3e-12 46.6 0.0 2.4e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70835.1 - 1e-07 32.1 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 EMR70836.1 - 5e-67 226.6 0.0 6.4e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PQ-loop PF04193.14 EMR70838.1 - 1.8e-38 130.1 14.2 1.7e-20 72.5 0.3 3.1 3 0 0 3 3 3 2 PQ loop repeat MnhB PF04039.13 EMR70838.1 - 0.073 13.4 1.8 0.13 12.6 0.1 2.2 3 0 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter 7tm_3 PF00003.22 EMR70838.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.2 2 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR S1-P1_nuclease PF02265.16 EMR70840.1 - 3e-74 250.0 0.1 3.4e-74 249.9 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PSI_PSAK PF01241.18 EMR70840.1 - 0.14 12.2 0.5 0.25 11.4 0.5 1.4 1 0 0 1 1 1 0 Photosystem I psaG / psaK Glyco_hydro_18 PF00704.28 EMR70841.1 - 2.3e-69 234.5 0.0 3e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EMR70841.1 - 3.1e-05 24.3 19.5 0.00011 22.6 19.6 1.9 1 1 1 2 2 2 1 Chitin recognition protein adh_short_C2 PF13561.6 EMR70842.1 - 1.5e-51 175.2 0.1 2e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR70842.1 - 4.9e-45 153.4 0.3 5.9e-45 153.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR70842.1 - 1.7e-08 34.6 0.4 2.4e-08 34.1 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR70842.1 - 1.6e-05 24.5 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMR70842.1 - 0.014 14.8 0.0 0.051 12.9 0.0 1.8 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EMR70842.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HLH PF00010.26 EMR70843.1 - 2.3e-08 33.9 0.1 4.8e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HD_4 PF13328.6 EMR70843.1 - 0.0083 15.9 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 1 HD domain DUF773 PF05600.12 EMR70843.1 - 0.32 9.7 3.3 0.12 11.1 1.0 1.3 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 DUF3006 PF11213.8 EMR70843.1 - 0.33 11.2 3.1 4.4 7.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) Maf PF02545.14 EMR70844.1 - 7.7e-43 146.2 0.0 1.6e-42 145.2 0.0 1.5 1 1 0 1 1 1 1 Maf-like protein CDC45 PF02724.14 EMR70844.1 - 0.03 12.6 3.1 0.041 12.2 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.12 EMR70844.1 - 0.11 10.8 2.5 0.14 10.4 2.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Methyltransf_12 PF08242.12 EMR70844.1 - 0.12 13.2 0.2 0.23 12.2 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain BTB PF00651.31 EMR70844.1 - 0.19 12.0 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Presenilin PF01080.17 EMR70844.1 - 0.92 8.2 2.1 1.3 7.7 2.1 1.1 1 0 0 1 1 1 0 Presenilin ATP11 PF06644.11 EMR70844.1 - 8.5 6.1 6.7 14 5.3 6.7 1.3 1 0 0 1 1 1 0 ATP11 protein tRNA-synt_2b PF00587.25 EMR70845.1 - 9.1e-32 110.5 0.0 2.8e-28 99.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMR70845.1 - 1.9e-06 27.9 0.0 3.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain Utp11 PF03998.13 EMR70847.1 - 1.6e-62 211.7 19.6 1.8e-62 211.5 19.6 1.0 1 0 0 1 1 1 1 Utp11 protein CTF_NFI PF00859.18 EMR70847.1 - 0.2 11.6 0.1 5.6 6.8 0.0 2.0 1 1 1 2 2 2 0 CTF/NF-I family transcription modulation region SLATT_5 PF18160.1 EMR70847.1 - 1.1 8.5 3.3 0.45 9.8 0.2 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF45 PF01863.17 EMR70847.1 - 1.8 8.5 6.7 1.2 9.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 DASH_Dam1 PF08653.10 EMR70848.1 - 0.043 13.6 0.2 3.1 7.7 0.0 3.5 4 0 0 4 4 4 0 DASH complex subunit Dam1 COG6 PF06419.11 EMR70848.1 - 0.066 11.4 0.5 0.16 10.1 0.0 1.7 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 KxDL PF10241.9 EMR70848.1 - 0.12 12.6 1.5 8.1 6.8 0.1 3.8 4 1 1 5 5 5 0 Uncharacterized conserved protein WD40 PF00400.32 EMR70849.1 - 3.1e-07 31.0 10.0 0.58 11.1 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 EMR70849.1 - 0.027 13.1 0.1 3.6 6.1 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EMR70849.1 - 0.027 14.7 0.0 10 6.5 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.28 EMR70850.1 - 8.5e-87 291.5 0.0 1e-86 291.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme p450 PF00067.22 EMR70851.1 - 8.5e-62 209.4 0.0 1.1e-61 209.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ILVD_EDD PF00920.21 EMR70852.1 - 9.2e-64 215.9 0.1 1.1e-63 215.7 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Chitin_synth_1 PF01644.17 EMR70854.1 - 4.2e-77 257.7 0.0 6.6e-77 257.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EMR70854.1 - 4.6e-28 97.0 0.2 1e-27 95.9 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EMR70854.1 - 4.3e-23 81.7 8.9 4.1e-20 71.9 0.0 2.9 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EMR70854.1 - 1.4e-06 28.4 4.5 1.4e-06 28.4 4.5 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMR70854.1 - 0.12 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 NBD94 PF16830.5 EMR70855.1 - 0.17 12.3 0.0 0.21 12.0 0.0 1.1 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Fringe PF02434.16 EMR70856.1 - 9.5e-07 28.5 0.0 2.4e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 EMR70856.1 - 0.0008 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAN_3 PF08277.12 EMR70856.1 - 0.0025 17.6 1.0 0.0047 16.7 1.0 1.4 1 0 0 1 1 1 1 PAN-like domain PAN_2 PF08276.11 EMR70856.1 - 0.044 13.9 0.9 0.093 12.9 0.9 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.6 EMR70856.1 - 0.097 12.6 1.7 0.21 11.5 1.7 1.5 1 0 0 1 1 1 0 PAN domain Glyco_hydro_9 PF00759.19 EMR70857.1 - 0.024 14.1 0.9 0.034 13.6 0.9 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 SMBP PF16785.5 EMR70857.1 - 0.036 14.3 6.9 0.34 11.1 1.9 2.6 2 0 0 2 2 2 0 Small metal-binding protein Prefoldin PF02996.17 EMR70857.1 - 4 7.4 8.4 0.32 10.9 3.1 1.9 2 0 0 2 2 2 0 Prefoldin subunit ABC_tran PF00005.27 EMR70858.1 - 8.5e-21 74.9 0.0 1.6e-08 35.1 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMR70858.1 - 2.4e-05 24.3 4.1 0.27 11.0 0.6 3.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EMR70858.1 - 0.00024 21.2 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EMR70858.1 - 0.0041 17.6 0.2 0.034 14.6 0.3 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMR70858.1 - 0.0099 15.6 0.0 0.26 11.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EMR70858.1 - 0.052 14.0 0.0 0.64 10.4 0.0 2.9 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMR70858.1 - 0.053 13.3 0.0 6 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 EMR70858.1 - 0.054 13.0 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_33 PF13671.6 EMR70858.1 - 0.12 12.6 0.0 4.4 7.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMR70858.1 - 0.12 12.7 0.0 11 6.3 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 EMR70858.1 - 0.15 12.4 0.3 7.2 7.0 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 EMR70858.1 - 0.2 12.0 0.0 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Rad60-SLD_2 PF13881.6 EMR70859.1 - 5.9e-13 48.9 0.1 1.5e-12 47.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMR70859.1 - 0.00016 22.1 0.0 0.00039 20.9 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EMR70859.1 - 0.0023 17.7 0.0 0.0048 16.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Glyco_hydro_17 PF00332.18 EMR70860.1 - 2.8e-05 23.9 0.6 6.2e-05 22.7 0.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Fungal_lectin PF07938.12 EMR70861.1 - 7.5e-07 28.8 5.2 0.0039 16.6 0.2 3.1 1 1 0 3 3 3 2 Fungal fucose-specific lectin gp37_C PF12604.8 EMR70861.1 - 0.049 13.3 2.0 0.058 13.1 0.6 1.8 2 0 0 2 2 2 0 Tail fibre protein gp37 C terminal YtxH PF12732.7 EMR70861.1 - 0.091 13.3 0.0 0.091 13.3 0.0 2.1 2 0 0 2 2 2 0 YtxH-like protein DUF3976 PF13121.6 EMR70861.1 - 0.22 11.7 2.0 0.43 10.7 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) SET PF00856.28 EMR70862.1 - 2.9e-12 47.3 0.0 3.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 SET domain AsnC_trans_reg PF01037.21 EMR70862.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain PapA_C PF16911.5 EMR70862.1 - 0.16 12.0 0.0 3.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus FAD_binding_3 PF01494.19 EMR70863.1 - 2e-15 56.9 1.1 3.7e-12 46.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMR70863.1 - 8.4e-05 22.7 0.2 0.00053 20.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR70863.1 - 0.0049 16.1 0.1 0.0069 15.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR70863.1 - 0.0055 16.3 0.4 0.015 14.9 0.3 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR70863.1 - 0.016 15.8 0.1 0.041 14.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR70863.1 - 0.03 14.3 0.3 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EMR70863.1 - 0.13 11.3 0.1 0.25 10.4 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein SE PF08491.10 EMR70863.1 - 0.14 11.2 0.0 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase UMP1 PF05348.11 EMR70864.1 - 2.3e-38 131.1 0.0 3.2e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SKG6 PF08693.10 EMR70865.1 - 0.03 13.7 6.2 0.062 12.7 6.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DIOX_N PF14226.6 EMR70866.1 - 3.8e-18 66.3 0.0 1.2e-17 64.8 0.0 1.8 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR70866.1 - 1.3e-09 38.4 0.0 2.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HicA_toxin PF07927.12 EMR70867.1 - 0.036 14.1 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, CDC14 PF08045.11 EMR70869.1 - 3e-128 426.9 0.0 4.5e-128 426.3 0.0 1.2 1 0 0 1 1 1 1 Cell division control protein 14, SIN component PNGaseA PF12222.8 EMR70870.1 - 4.3e-67 226.9 1.1 6.2e-55 186.8 0.3 2.2 1 1 1 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A polyprenyl_synt PF00348.17 EMR70871.1 - 1.9e-64 217.2 0.0 2.3e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase mRNA_cap_enzyme PF01331.19 EMR70872.1 - 1.5e-57 194.6 0.0 1.9e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EMR70872.1 - 3.5e-32 111.2 0.0 6e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EMR70872.1 - 8.9e-09 35.3 0.0 5.6e-06 26.1 0.1 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain PUF PF00806.19 EMR70873.1 - 9.9e-25 84.8 0.0 0.0018 17.9 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EMR70873.1 - 1.5e-13 50.3 0.0 3.5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M28 PF04389.17 EMR70874.1 - 1.9e-16 60.4 0.0 2.2e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.25 EMR70875.1 - 9.4e-52 176.0 0.0 3.2e-48 164.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR70875.1 - 2.7e-32 112.1 0.0 8.2e-31 107.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR70875.1 - 5.5e-05 22.6 0.0 8.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EMR70875.1 - 0.00034 19.7 0.0 0.00059 18.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EMR70875.1 - 0.0011 18.2 0.1 0.0024 17.0 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EMR70875.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EMR70875.1 - 0.15 11.0 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Tyrosinase PF00264.20 EMR70876.1 - 6.7e-52 177.0 0.0 1.3e-51 176.0 0.0 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Mem_trans PF03547.18 EMR70877.1 - 2.3e-51 174.4 0.0 5.4e-51 173.2 0.0 1.5 1 1 0 1 1 1 1 Membrane transport protein Asp PF00026.23 EMR70879.1 - 1e-58 199.3 0.2 1.2e-58 199.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR70879.1 - 4.9e-11 43.2 0.7 8.6e-05 22.8 0.1 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal AT_hook PF02178.19 EMR70880.1 - 0.021 14.6 4.0 0.021 14.6 4.0 3.5 2 0 0 2 2 2 0 AT hook motif Menin PF05053.13 EMR70880.1 - 0.59 8.4 13.9 0.73 8.1 13.9 1.1 1 0 0 1 1 1 0 Menin Ferlin_C PF16165.5 EMR70880.1 - 3.5 7.5 11.9 0.25 11.3 6.1 1.9 2 0 0 2 2 2 0 Ferlin C-terminus SlyX PF04102.12 EMR70881.1 - 6.6e-05 23.4 1.1 0.00045 20.8 0.2 2.1 2 0 0 2 2 2 1 SlyX COG2 PF06148.11 EMR70881.1 - 0.0018 18.4 0.1 0.0028 17.7 0.1 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 SKA1 PF07160.12 EMR70881.1 - 0.0027 17.6 1.3 0.0034 17.3 1.3 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 LXG PF04740.12 EMR70881.1 - 0.0093 15.7 0.7 0.018 14.8 0.7 1.4 1 0 0 1 1 1 1 LXG domain of WXG superfamily DUF16 PF01519.16 EMR70881.1 - 0.014 15.8 0.5 0.014 15.8 0.5 1.4 2 0 0 2 2 1 0 Protein of unknown function DUF16 HAP1_N PF04849.13 EMR70881.1 - 0.021 14.1 0.7 0.031 13.5 0.7 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.8 EMR70881.1 - 0.022 14.8 1.4 0.043 13.8 1.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 EMR70881.1 - 0.025 14.8 1.7 0.042 14.1 1.7 1.3 1 0 0 1 1 1 0 Haemolysin XhlA ADIP PF11559.8 EMR70881.1 - 0.034 14.2 1.6 0.034 14.2 1.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 EMR70881.1 - 0.047 13.9 0.4 0.076 13.2 0.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Filament PF00038.21 EMR70881.1 - 0.047 13.3 4.6 0.031 13.9 3.3 1.4 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 EMR70881.1 - 0.05 12.5 1.3 0.081 11.8 1.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Katanin_con80 PF13925.6 EMR70881.1 - 0.057 13.5 0.3 0.08 13.0 0.3 1.2 1 0 0 1 1 1 0 con80 domain of Katanin DASH_Spc19 PF08287.11 EMR70881.1 - 0.06 13.2 3.2 0.087 12.7 3.2 1.3 1 1 0 1 1 1 0 Spc19 DUF4407 PF14362.6 EMR70881.1 - 0.072 12.4 6.2 0.078 12.3 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 EMR70881.1 - 0.092 13.1 3.6 3.6 7.9 0.8 2.3 1 1 1 2 2 2 0 Tup N-terminal Csm1_N PF18504.1 EMR70881.1 - 0.098 13.0 1.8 0.3 11.4 1.8 1.8 1 1 0 1 1 1 0 Csm1 N-terminal domain ATG16 PF08614.11 EMR70881.1 - 0.15 12.3 8.1 0.074 13.3 1.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) OEP PF02321.18 EMR70881.1 - 0.21 11.4 5.8 0.38 10.5 5.8 1.4 1 1 0 1 1 1 0 Outer membrane efflux protein GAIN_A PF18619.1 EMR70881.1 - 0.26 11.5 1.4 2.5 8.4 0.4 2.4 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF724 PF05266.14 EMR70881.1 - 0.3 10.9 3.4 0.43 10.4 3.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 EMR70881.1 - 0.46 10.3 5.6 0.27 11.0 1.6 2.3 2 1 0 2 2 2 0 Septum formation initiator Ndc1_Nup PF09531.10 EMR70881.1 - 1.1 7.8 3.4 1.2 7.7 3.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BST2 PF16716.5 EMR70881.1 - 1.4 9.6 6.6 0.11 13.1 1.5 1.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Ribosomal_L12_N PF16320.5 EMR70881.1 - 4.6 7.0 8.8 0.58 9.9 0.9 2.5 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain zf-TRAF PF02176.18 EMR70882.1 - 1.9e-10 41.2 37.8 9e-07 29.5 2.8 4.0 2 1 2 4 4 3 3 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EMR70882.1 - 2e-08 34.6 26.8 7.5e-08 32.7 9.1 2.5 2 0 0 2 2 2 2 TRAF-like zinc-finger zf-C3HC4_2 PF13923.6 EMR70882.1 - 4.7e-07 29.6 7.0 4.7e-07 29.6 7.0 3.8 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR70882.1 - 2.3e-06 27.3 4.6 2.3e-06 27.3 4.6 3.6 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR70882.1 - 2.9e-05 24.0 6.6 2.9e-05 24.0 6.6 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMR70882.1 - 3.6e-05 23.5 6.5 3.6e-05 23.5 6.5 3.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMR70882.1 - 4.4e-05 23.4 6.8 4.4e-05 23.4 6.8 3.7 2 2 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EMR70882.1 - 5.9e-05 23.1 7.1 5.9e-05 23.1 7.1 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EMR70882.1 - 7.5e-05 23.0 5.9 7.5e-05 23.0 5.9 3.7 2 1 2 4 4 2 1 Ring finger domain Sina PF03145.16 EMR70882.1 - 0.00022 21.2 0.5 0.00022 21.2 0.5 3.3 1 1 2 3 3 2 1 Seven in absentia protein family zf-RING_6 PF14835.6 EMR70882.1 - 0.013 15.3 0.8 0.042 13.7 0.8 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EMR70882.1 - 0.013 15.6 5.1 0.013 15.6 5.1 3.0 2 1 0 2 2 1 0 zinc RING finger of MSL2 DUF4606 PF15379.6 EMR70882.1 - 0.069 13.4 2.2 0.3 11.4 2.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) U-box PF04564.15 EMR70882.1 - 0.41 10.8 1.8 1.9 8.7 0.1 2.9 4 0 0 4 4 3 0 U-box domain Exo_endo_phos PF03372.23 EMR70883.1 - 3.2e-09 36.6 0.3 1.3e-08 34.6 0.2 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OPT PF03169.15 EMR70885.1 - 2.3e-54 185.1 4.4 2.7e-54 184.9 4.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Yip1 PF04893.17 EMR70885.1 - 4.7 6.9 15.6 0.63 9.7 8.5 2.3 1 1 1 2 2 2 0 Yip1 domain YbgT_YccB PF08173.11 EMR70885.1 - 5 7.4 9.4 1.3 9.2 2.8 2.9 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Piwi PF02171.17 EMR70886.1 - 9.3e-81 271.4 1.0 1.4e-80 270.8 1.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EMR70886.1 - 5.1e-22 79.0 0.0 1.5e-21 77.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EMR70886.1 - 3.6e-15 55.4 0.0 9.2e-14 50.9 0.0 2.5 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EMR70886.1 - 3.1e-12 46.6 0.0 1.3e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 EMR70886.1 - 1.3e-10 41.2 0.2 2.6e-10 40.3 0.2 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EMR70886.1 - 5.1e-06 26.6 0.0 1.9e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Mid domain of argonaute Suf PF05843.14 EMR70887.1 - 1.1e-54 186.4 0.7 3e-53 181.7 0.1 3.9 4 2 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EMR70887.1 - 1.8e-05 25.2 5.8 0.0023 18.6 0.0 5.8 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR70887.1 - 0.0012 19.3 0.1 0.13 12.8 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR70887.1 - 0.0017 19.0 0.0 0.0081 16.8 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat PP2C_C PF07830.13 EMR70887.1 - 0.029 14.8 0.0 0.091 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain HAT PF02184.16 EMR70887.1 - 0.11 12.5 2.6 0.2 11.7 0.1 2.8 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TGT PF01702.18 EMR70888.1 - 0.077 12.1 0.3 0.096 11.8 0.3 1.1 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase zf-C2H2_2 PF12756.7 EMR70888.1 - 0.19 12.1 6.4 1.5 9.2 4.9 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EMR70888.1 - 1.4 9.9 9.5 1.9 9.6 0.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMR70888.1 - 3.7 8.1 8.4 2.6 8.6 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain AMMECR1 PF01871.17 EMR70889.1 - 1.3e-44 151.8 0.0 1.8e-44 151.3 0.0 1.3 1 1 0 1 1 1 1 AMMECR1 SR-25 PF10500.9 EMR70889.1 - 1.6 8.3 6.6 2.4 7.7 6.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ras PF00071.22 EMR70890.1 - 9.4e-40 135.9 0.0 3.3e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EMR70890.1 - 1.7e-11 44.4 0.0 3.7e-11 43.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EMR70890.1 - 0.0061 16.6 0.0 0.009 16.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EMR70890.1 - 0.0085 15.6 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family PRK PF00485.18 EMR70890.1 - 0.091 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Fungus-induced PF10917.8 EMR70890.1 - 4.1 7.8 8.2 26 5.2 0.1 2.6 2 0 0 2 2 2 0 Fungus-induced protein DUF4663 PF15668.5 EMR70891.1 - 0.16 11.0 3.4 0.23 10.5 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) DUF2070 PF09843.9 EMR70891.1 - 0.78 7.9 8.2 1.2 7.3 8.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SUR7 PF06687.12 EMR70891.1 - 0.95 9.1 10.1 3.6 7.2 6.1 2.1 1 1 1 2 2 2 0 SUR7/PalI family DUF455 PF04305.14 EMR70892.1 - 4.8e-87 291.6 0.3 5.4e-87 291.4 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) ASF1_hist_chap PF04729.13 EMR70893.1 - 2.9e-73 244.9 0.0 3.9e-73 244.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone FYDLN_acid PF09538.10 EMR70894.1 - 0.58 10.9 12.9 0.72 10.6 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PTR2 PF00854.21 EMR70895.1 - 1.8e-13 50.1 1.7 7.5e-13 48.1 1.9 1.7 2 0 0 2 2 2 1 POT family MFS_1 PF07690.16 EMR70895.1 - 2.5e-05 23.4 3.7 3.3e-05 23.0 3.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Asp PF00026.23 EMR70896.1 - 1.2e-58 199.0 2.2 2.4e-58 198.0 0.3 2.0 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR70896.1 - 5.1e-09 36.6 0.3 6.2e-08 33.1 0.3 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMR70896.1 - 0.00076 20.1 0.1 1.2 9.8 0.0 3.6 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EMR70896.1 - 0.018 15.6 0.0 11 6.7 0.0 3.6 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease AAA PF00004.29 EMR70898.1 - 4.7e-13 49.7 0.0 1.2e-12 48.4 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps36_ESCRT-II PF11605.8 EMR70898.1 - 0.05 13.8 0.0 0.7 10.1 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 AAA_5 PF07728.14 EMR70898.1 - 0.11 12.5 0.1 1.1 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Tannase PF07519.11 EMR70900.1 - 2.9e-111 372.7 0.1 3.5e-111 372.4 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase BBE PF08031.12 EMR70901.1 - 1.7e-10 40.8 0.5 3.9e-10 39.7 0.5 1.7 1 0 0 1 1 1 1 Berberine and berberine like Chordopox_A33R PF05966.12 EMR70902.1 - 0.0079 15.5 0.4 0.022 14.0 0.4 1.8 1 1 0 1 1 1 1 Chordopoxvirus A33R protein Hce2 PF14856.6 EMR70902.1 - 0.0095 16.2 0.3 0.015 15.5 0.3 1.4 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor zf-CCCH_3 PF15663.5 EMR70902.1 - 0.061 13.5 0.3 0.08 13.2 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger containing family adh_short PF00106.25 EMR70903.1 - 2.7e-18 66.2 0.2 3.6e-18 65.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR70903.1 - 2.9e-17 63.0 0.4 6e-17 62.0 0.4 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR70903.1 - 1.7e-06 28.0 0.2 3.1e-06 27.2 0.2 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 EMR70904.1 - 2.8e-68 230.7 0.0 3.4e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 EMR70905.1 - 1.2e-12 48.8 0.6 1.5e-12 48.5 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RasGEF_N_2 PF14663.6 EMR70905.1 - 0.087 13.2 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain UbiA PF01040.18 EMR70906.1 - 3.2e-24 85.6 7.7 3.2e-24 85.6 7.7 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_3 PF01494.19 EMR70909.1 - 2.3e-56 191.5 0.0 2.8e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR70909.1 - 2.7e-10 40.4 1.2 2.8e-05 23.9 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR70909.1 - 1.9e-06 27.4 0.1 0.00014 21.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR70909.1 - 6.2e-06 25.6 1.7 4e-05 22.9 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EMR70909.1 - 2.2e-05 23.4 1.1 4.9e-05 22.2 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EMR70909.1 - 3e-05 24.1 0.5 0.00024 21.3 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR70909.1 - 8.4e-05 21.9 0.3 0.0067 15.7 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR70909.1 - 0.00039 20.9 0.1 0.033 14.8 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR70909.1 - 0.0025 17.1 0.3 0.0039 16.4 0.3 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EMR70909.1 - 0.0032 16.6 0.2 0.0047 16.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.16 EMR70909.1 - 0.0065 16.1 0.2 0.012 15.2 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EMR70909.1 - 0.011 15.6 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMR70909.1 - 0.021 15.2 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 EMR70909.1 - 0.055 13.7 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 EMR70909.1 - 0.087 12.2 0.3 2 7.7 0.5 2.1 2 0 0 2 2 2 0 ThiF family Glu_dehyd_C PF16912.5 EMR70909.1 - 0.096 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_oxidored PF12831.7 EMR70909.1 - 0.11 11.8 1.3 0.39 10.0 1.3 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase XdhC_C PF13478.6 EMR70909.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain FAD_binding_4 PF01565.23 EMR70910.1 - 7e-20 71.2 0.9 7e-20 71.2 0.9 1.6 2 0 0 2 2 2 1 FAD binding domain APH PF01636.23 EMR70911.1 - 1.7e-12 47.8 0.0 2.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMR70911.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EMR70911.1 - 0.031 13.1 0.0 0.64 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF4135 PF13575.6 EMR70911.1 - 0.04 13.2 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase PF00069.25 EMR70911.1 - 0.066 12.6 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain FAD_binding_3 PF01494.19 EMR70912.1 - 5.6e-25 88.3 0.1 3.8e-24 85.6 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR70912.1 - 1.1e-05 24.9 0.3 3.1e-05 23.4 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR70912.1 - 6e-05 22.8 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR70912.1 - 0.0002 21.5 0.1 0.00061 20.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR70912.1 - 0.0004 19.7 0.0 0.0015 17.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EMR70912.1 - 0.00047 19.1 0.0 0.041 12.7 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.24 EMR70912.1 - 0.002 17.3 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EMR70912.1 - 0.0052 15.9 0.0 0.3 10.1 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 EMR70912.1 - 0.0072 15.7 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EMR70912.1 - 0.028 13.1 0.1 0.047 12.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 EMR70912.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.22 EMR70914.1 - 3.7e-17 62.2 0.1 3e-13 49.4 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 SUIM_assoc PF16619.5 EMR70915.1 - 2.9 8.0 9.5 6.4 6.9 9.5 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 EMR70918.1 - 6.1e-24 84.6 46.8 6.1e-24 84.6 46.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 EMR70919.1 - 1.7e-20 72.9 0.3 7.2e-13 48.5 0.3 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR70919.1 - 8.4e-18 64.4 1.4 7.1e-13 48.6 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EMR70919.1 - 0.034 14.2 0.0 2.1 8.4 0.1 2.9 2 1 0 2 2 2 0 SLIDE SANT_DAMP1_like PF16282.5 EMR70919.1 - 0.13 12.5 0.0 12 6.2 0.0 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Ank_4 PF13637.6 EMR70920.1 - 0.082 13.5 0.0 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) NPP1 PF05630.11 EMR70921.1 - 3.6e-64 216.5 1.1 4.3e-64 216.3 1.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Zn_clus PF00172.18 EMR70922.1 - 0.00011 22.3 14.8 0.00021 21.4 14.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EMR70923.1 - 0.025 15.0 7.2 0.16 12.5 0.5 3.3 2 1 0 2 2 2 0 Zinc finger, C2H2 type DUF753 PF05444.12 EMR70923.1 - 0.057 13.4 2.4 0.097 12.7 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF753) zf-C2H2_4 PF13894.6 EMR70923.1 - 0.067 14.1 6.4 4.2 8.5 1.3 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 EMR70924.1 - 1.4e-45 155.7 0.0 2.2e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR70924.1 - 1.6e-27 96.5 0.0 2.5e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR70924.1 - 0.0047 16.3 0.0 0.025 13.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMR70924.1 - 0.0084 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L1 PF00687.21 EMR70925.1 - 6.3e-45 153.4 0.1 7.2e-45 153.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Amino_oxidase PF01593.24 EMR70927.1 - 8.6e-33 114.3 0.0 1.2e-32 113.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR70927.1 - 2e-09 37.5 0.0 6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR70927.1 - 0.0094 15.2 0.0 0.047 12.9 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR70927.1 - 0.12 11.9 0.8 0.28 10.7 0.1 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EMR70927.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.16 EMR70930.1 - 1.3e-19 70.3 34.3 1.3e-12 47.3 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR70930.1 - 2.6e-09 36.5 20.7 2.9e-08 33.0 20.7 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter Pollen_allerg_1 PF01357.21 EMR70931.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Pollen allergen GPHH PF16905.5 EMR70931.1 - 0.13 12.0 0.1 4.7 7.1 0.3 2.5 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated DAO PF01266.24 EMR70933.1 - 3.2e-30 105.9 0.0 4.5e-25 89.0 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR70933.1 - 1.2e-07 31.1 0.1 2.2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMR70933.1 - 9.1e-07 28.3 0.0 2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EMR70933.1 - 1.3e-06 28.0 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR70933.1 - 2.9e-06 26.8 0.0 5.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR70933.1 - 4.3e-06 25.7 0.1 8.7e-06 24.7 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EMR70933.1 - 1e-05 25.7 0.0 7.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR70933.1 - 5.3e-05 22.6 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR70933.1 - 8.1e-05 22.0 0.4 0.0001 21.7 0.4 1.3 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EMR70933.1 - 0.0001 21.5 0.1 0.00016 20.9 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EMR70933.1 - 0.00011 22.7 0.0 0.00026 21.5 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR70933.1 - 0.0077 15.3 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 EMR70933.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.6 EMR70933.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 EMR70933.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 EMR70933.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 EMR70933.1 - 0.17 11.1 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3844 PF12955.7 EMR70934.1 - 1.3e-34 118.4 2.6 1.3e-34 118.4 2.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) LSM PF01423.22 EMR70935.1 - 4.2e-20 71.2 0.7 5.2e-20 70.9 0.7 1.1 1 0 0 1 1 1 1 LSM domain GMC_oxred_C PF05199.13 EMR70936.1 - 9.9e-36 123.4 0.1 1.6e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR70936.1 - 8.8e-31 107.4 0.0 1.1e-30 107.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DUF3716 PF12511.8 EMR70937.1 - 5.6e-07 29.5 6.2 8.7e-07 28.9 6.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Rubredoxin_2 PF18073.1 EMR70937.1 - 6.9 6.5 7.8 27 4.6 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain FAD_binding_3 PF01494.19 EMR70938.1 - 1.6e-16 60.5 0.0 2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.25 EMR70940.1 - 3e-26 92.4 0.0 3.8e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR70940.1 - 8.2e-14 51.5 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR70940.1 - 4.6e-09 35.5 0.0 7.2e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EMR70940.1 - 0.00022 21.3 0.0 0.0016 18.4 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family RNR_inhib PF08591.10 EMR70941.1 - 2.1e-34 119.0 0.1 4.2e-34 118.1 0.1 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor TPR_12 PF13424.6 EMR70942.1 - 2.1e-27 95.2 9.5 1.1e-11 44.9 1.1 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EMR70942.1 - 7.5e-24 82.9 6.5 1.7e-08 34.0 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EMR70942.1 - 6.1e-10 38.5 1.9 0.01 15.9 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR70942.1 - 3.4e-09 37.1 0.5 0.00089 19.7 0.0 4.2 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMR70942.1 - 3.6e-08 33.9 0.6 0.00059 20.4 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMR70942.1 - 4.8e-07 30.1 3.5 1.1 10.3 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMR70942.1 - 2.2e-06 27.3 1.3 0.014 15.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 EMR70942.1 - 2.9e-06 27.4 1.7 0.13 13.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMR70942.1 - 2.1e-05 24.6 0.2 0.97 10.0 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMR70942.1 - 2.2e-05 24.8 1.4 1.7 9.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EMR70942.1 - 7.3e-05 22.3 0.4 0.00016 21.1 0.4 1.6 1 1 0 1 1 1 1 MalT-like TPR region Foie-gras_1 PF11817.8 EMR70942.1 - 0.00031 20.4 0.2 0.98 9.0 0.0 3.0 2 1 1 3 3 3 2 Foie gras liver health family 1 PPR PF01535.20 EMR70942.1 - 0.00061 19.9 0.1 0.22 11.9 0.0 3.9 4 0 0 4 4 4 1 PPR repeat TPR_20 PF14561.6 EMR70942.1 - 0.008 16.5 0.1 4.1 7.8 0.0 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR70942.1 - 0.012 15.8 0.7 0.11 12.7 0.1 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EMR70942.1 - 0.012 15.7 1.1 3.4 8.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Paf67 PF10255.9 EMR70942.1 - 0.041 12.9 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 HrpB1_HrpK PF09613.10 EMR70942.1 - 0.041 13.5 0.3 2 8.1 0.0 2.9 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 EMR70942.1 - 0.045 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 EMR70942.1 - 0.083 12.7 2.6 0.33 10.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 EMR70942.1 - 0.096 12.4 0.5 0.76 9.5 0.0 2.4 3 0 0 3 3 3 0 26S proteasome subunit RPN7 PPR_1 PF12854.7 EMR70942.1 - 0.097 12.4 0.7 0.91 9.3 0.0 2.7 3 0 0 3 3 3 0 PPR repeat TPR_3 PF07720.12 EMR70942.1 - 0.12 12.3 1.0 20 5.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Phosducin PF02114.16 EMR70943.1 - 2.5e-14 52.9 0.1 3.4e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EMR70943.1 - 0.0039 17.2 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TMA7 PF09072.10 EMR70943.1 - 2.4 9.0 7.5 12 6.8 1.2 2.5 2 0 0 2 2 2 0 Translation machinery associated TMA7 GMC_oxred_N PF00732.19 EMR70944.1 - 1.3e-54 185.6 0.0 2.1e-54 184.9 0.0 1.3 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR70944.1 - 2.3e-34 119.0 0.0 3.8e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR70944.1 - 2.1e-06 27.1 0.9 0.0047 16.1 1.6 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EMR70944.1 - 0.00021 20.6 0.1 0.00034 19.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EMR70944.1 - 0.00027 20.1 0.4 0.0004 19.6 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EMR70944.1 - 0.00028 20.6 0.4 0.0011 18.6 0.8 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR70944.1 - 0.0016 18.6 0.7 0.0035 17.5 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR70944.1 - 0.015 14.6 0.2 0.025 13.8 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR70944.1 - 0.25 10.1 0.1 0.37 9.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 EMR70944.1 - 0.32 9.6 0.5 0.46 9.1 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein RTC PF01137.21 EMR70945.1 - 1e-45 155.7 0.0 2.3e-45 154.5 0.0 1.5 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase REV PF00424.18 EMR70945.1 - 0.95 9.5 9.0 7.3 6.7 0.2 3.4 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Phosphodiest PF01663.22 EMR70946.1 - 1.4e-91 307.8 0.3 1.4e-91 307.8 0.3 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMR70946.1 - 0.0042 16.5 0.0 0.1 11.9 0.0 2.3 2 0 0 2 2 2 1 Sulfatase Ribosomal_60s PF00428.19 EMR70946.1 - 1.2 9.8 9.9 4.1 8.0 9.9 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_S27e PF01667.17 EMR70947.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EMR70947.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding LRR_8 PF13855.6 EMR70948.1 - 1.9e-06 27.5 16.2 0.00015 21.4 3.2 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EMR70948.1 - 0.00034 20.9 9.3 0.00095 19.5 7.3 2.7 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) FAD_binding_4 PF01565.23 EMR70949.1 - 2.5e-16 59.7 1.4 6.5e-16 58.3 1.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR70949.1 - 1.9e-12 47.1 0.0 3.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like TadZ_N PF16968.5 EMR70949.1 - 0.036 13.8 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Pilus assembly protein TadZ N-terminal tRNA-synt_2 PF00152.20 EMR70950.1 - 2.6e-71 240.3 0.0 3.3e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMR70950.1 - 1.2e-07 31.6 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PBP PF01161.20 EMR70951.1 - 1.3e-14 54.7 0.0 1.7e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein NST1 PF13945.6 EMR70952.1 - 0.0012 19.0 10.1 0.0022 18.1 10.1 1.3 1 0 0 1 1 1 1 Salt tolerance down-regulator Presenilin PF01080.17 EMR70952.1 - 0.1 11.3 1.0 0.13 11.0 1.0 1.1 1 0 0 1 1 1 0 Presenilin SWIM PF04434.17 EMR70952.1 - 0.49 10.1 3.3 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 SWIM zinc finger Hid1 PF12722.7 EMR70952.1 - 0.66 8.0 9.0 0.91 7.6 9.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ADK PF00406.22 EMR70953.1 - 3.8e-58 195.9 0.0 5.2e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EMR70953.1 - 1.5e-22 80.5 0.2 3e-22 79.5 0.2 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EMR70953.1 - 1.4e-17 63.3 0.0 3.8e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EMR70953.1 - 7.3e-06 26.6 0.1 2.5e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMR70953.1 - 0.0011 19.2 0.0 0.0024 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain STALD PF18185.1 EMR70953.1 - 0.064 12.6 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Sir2- and TIR-associating SLOG family Phage_GPD PF05954.11 EMR70954.1 - 0.07 12.4 0.2 0.13 11.6 0.1 1.4 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) IMUP PF15761.5 EMR70954.1 - 0.29 11.8 7.3 0.48 11.1 7.3 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein MitMem_reg PF13012.6 EMR70956.1 - 1.3e-37 128.6 0.1 2.5e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EMR70956.1 - 1.7e-32 111.8 0.1 4.1e-32 110.6 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EMR70956.1 - 0.023 14.4 2.7 0.035 13.8 2.7 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain TRPM_tetra PF16519.5 EMR70956.1 - 0.19 11.9 2.2 7.1 6.8 0.1 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF1682 PF07946.14 EMR70956.1 - 1 8.5 5.5 1.5 7.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) bZIP_1 PF00170.21 EMR70957.1 - 7.1e-06 26.0 9.3 1e-05 25.5 9.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMR70957.1 - 4.2e-05 23.5 12.9 5.6e-05 23.1 12.0 1.6 1 1 1 2 2 2 1 Basic region leucine zipper MCC-bdg_PDZ PF10506.9 EMR70957.1 - 0.00063 19.7 0.6 0.0012 18.8 0.6 1.5 1 0 0 1 1 1 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Takusan PF04822.13 EMR70957.1 - 0.0018 18.1 2.8 0.0028 17.5 2.2 1.8 1 1 0 1 1 1 1 Takusan bZIP_Maf PF03131.17 EMR70957.1 - 0.013 16.0 6.5 0.02 15.4 6.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor FAM92 PF06730.11 EMR70957.1 - 0.023 14.1 1.9 0.031 13.7 1.9 1.3 1 1 0 1 1 1 0 FAM92 protein HLH PF00010.26 EMR70957.1 - 0.048 13.6 1.4 0.32 11.0 1.4 2.2 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain ATG16 PF08614.11 EMR70957.1 - 0.054 13.7 7.7 0.063 13.5 7.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMEM237 PF15383.6 EMR70957.1 - 0.18 10.9 0.4 0.2 10.7 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 APG6_N PF17675.1 EMR70957.1 - 0.28 11.7 5.1 0.33 11.5 5.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 EMR70957.1 - 1.4 8.2 6.0 1.7 7.9 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) p450 PF00067.22 EMR70958.1 - 2.8e-40 138.5 0.0 3.8e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EMR70959.1 - 5e-24 84.9 32.7 5.9e-23 81.4 32.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR70959.1 - 1.4e-14 53.5 7.8 2.2e-14 52.9 7.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMR70959.1 - 4.7 5.4 7.5 7 4.8 2.5 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Clat_adaptor_s PF01217.20 EMR70961.1 - 7.1e-44 149.2 0.0 1.6e-43 148.1 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Beta-lactamase PF00144.24 EMR70962.1 - 3.2e-28 99.0 0.2 4.7e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Hid1 PF12722.7 EMR70963.1 - 0.84 7.7 4.1 0.89 7.6 4.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 EMR70963.1 - 1.5 7.9 6.3 1.9 7.6 6.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter LRR_6 PF13516.6 EMR70964.1 - 0.0094 15.9 0.8 0.59 10.3 0.0 3.4 4 0 0 4 4 4 1 Leucine Rich repeat Glyco_trans_1_4 PF13692.6 EMR70965.1 - 2.2e-05 24.9 0.0 6.4e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3176 PF11374.8 EMR70966.1 - 6.2e-25 87.5 0.1 1.4e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3430 PF11912.8 EMR70967.1 - 0.00063 19.9 4.1 0.0014 18.8 4.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) Mito_carr PF00153.27 EMR70968.1 - 7.1e-57 189.3 6.0 2e-18 66.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_efflux PF01545.21 EMR70970.1 - 1.1e-49 168.9 4.3 1.6e-49 168.4 4.3 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 EMR70970.1 - 0.35 10.1 20.6 1.3 8.2 16.6 2.4 1 1 1 2 2 2 0 ZIP Zinc transporter Metal_resist PF13801.6 EMR70970.1 - 1 9.5 2.2 2.5 8.3 2.2 1.6 1 0 0 1 1 1 0 Heavy-metal resistance Sugar_tr PF00083.24 EMR70971.1 - 5.7e-18 65.0 3.0 3.8e-17 62.3 0.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR70972.1 - 1.9e-07 30.3 2.6 1.9e-07 30.3 2.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EMR70972.1 - 0.086 11.1 1.3 0.12 10.7 1.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2207 PF09972.9 EMR70972.1 - 0.17 10.6 0.6 0.22 10.2 0.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_C13 PF01650.18 EMR70973.1 - 4.4e-41 141.1 0.2 6.5e-41 140.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase C13 family zf-TFIIIC PF12660.7 EMR70974.1 - 2.4e-09 37.0 2.8 1.4e-08 34.6 2.3 2.5 2 1 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 EMR70974.1 - 1.2e-08 35.1 0.3 4e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term UQ_con PF00179.26 EMR70975.1 - 9.1e-19 67.5 0.0 9.4e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Uso1_p115_head PF04869.14 EMR70976.1 - 2.7e-24 85.9 0.1 5.2e-14 52.1 0.2 2.8 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EMR70976.1 - 7.8e-18 65.1 38.7 7.8e-18 65.1 38.7 3.6 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm PF00514.23 EMR70976.1 - 0.0055 16.7 0.1 0.07 13.2 0.0 2.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EMR70976.1 - 0.087 13.4 0.4 4.9 7.8 0.2 3.0 2 0 0 2 2 2 0 HEAT-like repeat Spc7 PF08317.11 EMR70976.1 - 2.7 6.8 64.6 0.15 10.9 7.6 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein RasGAP PF00616.19 EMR70979.1 - 6e-35 120.8 0.8 4.8e-21 75.4 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase MOR2-PAG1_C PF14225.6 EMR70979.1 - 0.023 14.6 2.3 0.037 13.9 0.4 2.4 2 0 0 2 2 2 0 Cell morphogenesis C-terminal XRN_M PF17846.1 EMR70980.1 - 3.3e-131 438.3 0.1 2.1e-130 435.6 0.1 2.0 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EMR70980.1 - 3.6e-99 331.1 0.6 5.3e-99 330.5 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus LAP1C PF05609.12 EMR70980.1 - 0.42 9.6 4.7 0.81 8.7 4.7 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) zf-CCHC PF00098.23 EMR70980.1 - 0.44 10.7 2.3 0.78 9.9 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EMR70980.1 - 1.2 9.0 6.6 0.21 11.4 3.0 1.6 2 0 0 2 2 2 0 Zinc knuckle Prp19 PF08606.11 EMR70981.1 - 9.6e-33 112.0 2.1 2.1e-32 110.9 2.1 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EMR70981.1 - 5.3e-15 55.5 0.0 4.3e-07 30.1 0.0 4.5 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMR70981.1 - 2.8e-12 46.9 0.5 0.0016 19.2 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat VID27 PF08553.10 EMR70981.1 - 6e-05 22.3 0.2 0.001 18.2 0.1 2.1 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain PQQ_2 PF13360.6 EMR70981.1 - 9.9e-05 22.0 1.5 0.04 13.5 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain WD40_like PF17005.5 EMR70981.1 - 0.00016 21.2 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain V_ATPase_I_N PF18670.1 EMR70981.1 - 0.0022 18.3 1.2 0.0036 17.7 0.2 1.9 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain zf-Nse PF11789.8 EMR70981.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EMR70981.1 - 0.048 13.8 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain Histidinol_dh PF00815.20 EMR70981.1 - 0.058 12.4 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase Aldo_ket_red PF00248.21 EMR70982.1 - 4.8e-62 209.8 0.0 5.5e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AIRC PF00731.20 EMR70983.1 - 4.3e-64 214.6 1.1 9.8e-64 213.4 0.6 1.9 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 EMR70983.1 - 1.6e-48 164.5 0.0 2.9e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EMR70983.1 - 2.8e-14 52.5 0.0 6e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EMR70983.1 - 0.00073 19.1 0.0 0.0051 16.4 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 EMR70983.1 - 0.00074 19.1 0.1 0.0053 16.3 0.0 2.1 2 0 0 2 2 2 1 Propionate catabolism activator 2-Hacid_dh_C PF02826.19 EMR70983.1 - 0.085 12.2 0.1 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.25 EMR70984.1 - 6e-10 39.4 0.0 7.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR70984.1 - 5.9e-06 26.6 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR70984.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_transf_25 PF01755.17 EMR70985.1 - 3.3e-12 46.7 0.0 1.6e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) WD40 PF00400.32 EMR70986.1 - 3.1e-39 132.2 24.7 1.3e-08 35.3 2.6 7.9 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR70986.1 - 1.7e-14 53.9 2.0 0.065 13.5 0.2 6.3 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 EMR70986.1 - 6e-13 48.1 2.2 6e-13 48.1 2.2 2.4 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 EMR70986.1 - 0.003 16.6 0.0 25 3.7 0.0 4.3 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EMR70986.1 - 0.025 13.9 0.1 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EMR70986.1 - 0.047 13.0 0.0 14 4.9 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain eIF2A PF08662.11 EMR70986.1 - 0.056 13.3 0.1 0.87 9.4 0.0 2.7 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A PAN_4 PF14295.6 EMR70988.1 - 0.0036 17.2 3.2 0.0073 16.2 2.4 1.9 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 EMR70988.1 - 0.052 13.5 4.4 0.073 13.0 2.2 2.6 2 1 0 2 2 2 0 PAN domain SUZ PF12752.7 EMR70989.1 - 0.001 19.8 13.0 0.001 19.8 13.0 3.1 3 1 0 3 3 3 1 SUZ domain SUZ-C PF12901.7 EMR70989.1 - 0.014 15.4 0.2 0.046 13.7 0.2 1.9 1 0 0 1 1 1 0 SUZ-C motif DUF1996 PF09362.10 EMR70990.1 - 7e-69 232.4 2.1 8.4e-69 232.1 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pkinase PF00069.25 EMR70991.1 - 1.9e-65 220.9 0.0 2.3e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR70991.1 - 4.2e-29 101.6 0.0 5.7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMR70991.1 - 0.011 14.7 0.1 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 EMR70991.1 - 0.024 15.4 5.3 0.024 15.3 3.4 2.0 2 0 0 2 2 2 0 Protein kinase C terminal domain Kinase-like PF14531.6 EMR70991.1 - 0.058 12.7 0.2 0.13 11.5 0.1 1.7 1 1 1 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EMR70991.1 - 0.063 12.0 0.0 0.078 11.7 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EMR70991.1 - 0.094 12.3 0.1 3 7.4 0.1 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DNase_NucA_NucB PF14040.6 EMR70992.1 - 0.0039 17.6 0.1 0.0086 16.4 0.0 1.6 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB THB PF18362.1 EMR70994.1 - 0.15 11.6 3.3 0.46 10.1 0.8 2.5 1 1 1 2 2 2 0 Tri-helix bundle domain Cyclin_N PF00134.23 EMR70995.1 - 0.001 18.8 0.5 0.0019 17.9 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain SNF2_N PF00176.23 EMR70996.1 - 2.9e-27 95.3 0.0 4.6e-26 91.4 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR70996.1 - 1.2e-06 28.9 0.1 2.8e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMR70996.1 - 0.00018 21.3 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EMR70996.1 - 0.02 14.9 0.0 7.1 6.6 0.0 3.0 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit DUF4246 PF14033.6 EMR70997.1 - 1.1e-174 581.8 0.3 1.3e-174 581.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EMR70997.1 - 0.028 14.8 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Dus PF01207.17 EMR70998.1 - 1.3e-32 113.1 0.0 3.9e-24 85.3 0.0 3.5 3 1 0 3 3 3 3 Dihydrouridine synthase (Dus) Neisseria_TspB PF05616.13 EMR70998.1 - 6 5.2 7.2 9.5 4.6 7.2 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ATP_sub_h PF10775.9 EMR71000.1 - 4e-27 94.0 0.6 6.8e-27 93.3 0.6 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 EMR71000.1 - 0.17 12.3 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Methyltransf_16 PF10294.9 EMR71001.1 - 4.8e-15 55.7 0.0 7.9e-11 42.0 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EMR71001.1 - 1.9e-06 27.8 0.0 2.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 EMR71002.1 - 2.9e-29 102.1 35.5 1.2e-28 100.1 36.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR71002.1 - 0.002 17.5 19.2 0.0067 15.8 7.1 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB GFA PF04828.14 EMR71004.1 - 9.2e-10 38.7 0.0 1e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 EMR71004.1 - 0.19 11.4 0.7 0.19 11.4 0.7 1.8 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Glyco_hydro_3_C PF01915.22 EMR71005.1 - 6.8e-48 163.3 0.0 1e-47 162.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR71005.1 - 2e-37 129.3 0.0 3.3e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR71005.1 - 9.9e-25 86.4 0.0 1.8e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.25 EMR71006.1 - 1.8e-69 234.0 0.0 2.4e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR71006.1 - 3.6e-32 111.7 0.0 5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EMR71006.1 - 3.5e-12 46.8 2.4 3.5e-12 46.8 2.4 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EMR71006.1 - 1.4e-09 37.7 0.1 8e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EMR71006.1 - 0.00014 20.9 0.3 0.00025 20.1 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EMR71006.1 - 0.0057 16.3 0.3 2 8.0 0.0 2.7 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EMR71006.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EMR71006.1 - 0.044 13.4 0.1 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EMR71006.1 - 0.055 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family C2 PF00168.30 EMR71006.1 - 0.071 13.4 0.0 2.9 8.2 0.0 2.6 2 0 0 2 2 2 0 C2 domain Adeno_E3_15_3 PF03307.14 EMR71006.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region FAD_binding_3 PF01494.19 EMR71007.1 - 2.2e-63 214.6 0.0 3.1e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR71007.1 - 0.00021 20.6 0.0 0.02 14.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR71007.1 - 0.00075 19.2 2.6 0.1 12.1 0.2 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR71007.1 - 0.12 12.7 0.1 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMR71007.1 - 0.19 10.9 0.0 16 4.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fe_hyd_lg_C PF02906.14 EMR71008.1 - 7.2e-50 169.9 0.0 2.3e-49 168.3 0.0 1.8 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fungal_trans PF04082.18 EMR71009.1 - 4.7e-11 42.2 0.0 1.5e-10 40.6 0.0 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain CDH-cyt PF16010.5 EMR71010.1 - 2.6e-20 72.9 0.7 4.7e-20 72.0 0.7 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 EMR71010.1 - 4.9e-06 26.3 5.6 9.3e-06 25.4 5.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DOMON PF03351.17 EMR71010.1 - 0.00015 22.0 0.4 0.00033 20.9 0.1 1.7 2 0 0 2 2 2 1 DOMON domain RAP1 PF07218.11 EMR71010.1 - 9 4.4 4.7 12 4.0 4.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RNase_H PF00075.24 EMR71011.1 - 1.7e-19 70.4 0.0 2.4e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EMR71011.1 - 0.0007 19.4 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase-like CorA PF01544.18 EMR71012.1 - 1.9e-06 27.4 10.8 9.6e-06 25.1 5.0 3.1 2 1 0 3 3 3 2 CorA-like Mg2+ transporter protein CD36 PF01130.21 EMR71012.1 - 0.0048 15.5 3.2 0.031 12.8 1.2 2.1 2 0 0 2 2 2 2 CD36 family DUF2526 PF10735.9 EMR71013.1 - 0.091 12.9 4.9 0.6 10.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) ATG16 PF08614.11 EMR71013.1 - 0.096 12.9 5.1 0.33 11.1 5.1 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Nop14 PF04147.12 EMR71013.1 - 8.6 4.4 6.8 2.8 6.1 4.1 1.5 2 0 0 2 2 2 0 Nop14-like family PH PF00169.29 EMR71014.1 - 1.5e-05 25.4 0.1 3.4e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EMR71014.1 - 0.00027 21.3 0.0 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF2981 PF11200.8 EMR71014.1 - 1.8 8.3 3.7 3.6 7.3 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) adh_short_C2 PF13561.6 EMR71015.1 - 6.1e-31 107.8 0.1 6.9e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR71015.1 - 6.9e-30 104.0 0.3 7.6e-30 103.8 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR71015.1 - 6.7e-13 48.9 0.2 7.9e-13 48.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR71015.1 - 0.011 15.3 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 EMR71015.1 - 0.015 15.2 0.1 0.018 14.9 0.1 1.1 1 0 0 1 1 1 0 YjeF-related protein N-terminus AdoHcyase_NAD PF00670.21 EMR71015.1 - 0.05 13.7 0.8 0.11 12.6 0.4 1.7 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR71015.1 - 0.061 12.6 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EMR71015.1 - 0.069 13.0 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_16 PF00722.21 EMR71016.1 - 6.5e-06 25.7 0.1 2.2e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DNA_pol_B_thumb PF14791.6 EMR71017.1 - 5.1e-21 74.6 0.1 1e-20 73.6 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EMR71017.1 - 1.2e-20 73.0 0.6 3.5e-20 71.6 0.6 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 EMR71017.1 - 1.4e-20 73.6 0.0 2.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm NTP_transf_2 PF01909.23 EMR71017.1 - 0.0059 16.9 0.0 0.027 14.8 0.0 2.0 1 1 1 2 2 2 1 Nucleotidyltransferase domain HHH_5 PF14520.6 EMR71017.1 - 0.018 15.7 0.0 0.06 14.0 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain TFIIE_alpha PF02002.17 EMR71018.1 - 1.2e-17 63.6 0.5 2.5e-17 62.6 0.5 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit PBP_sp32 PF07222.12 EMR71018.1 - 0.047 13.2 12.0 0.1 12.1 12.0 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Myc_N PF01056.18 EMR71018.1 - 0.065 13.1 19.4 0.17 11.7 19.4 1.7 1 1 0 1 1 1 0 Myc amino-terminal region Importin_rep_6 PF18829.1 EMR71018.1 - 0.084 13.0 7.3 0.19 11.9 7.3 1.6 1 0 0 1 1 1 0 Importin repeat 6 Methyltransf_34 PF11312.8 EMR71018.1 - 0.092 12.0 1.6 0.17 11.1 1.6 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase BUD22 PF09073.10 EMR71018.1 - 0.24 10.7 23.9 0.34 10.2 23.9 1.2 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EMR71018.1 - 0.42 9.9 18.3 0.32 10.3 13.4 2.2 2 0 0 2 2 2 0 NOA36 protein Voldacs PF03517.13 EMR71018.1 - 0.75 9.9 11.4 1.4 9.0 11.4 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Nop14 PF04147.12 EMR71018.1 - 1.2 7.2 22.9 2.1 6.5 22.9 1.3 1 0 0 1 1 1 0 Nop14-like family PA26 PF04636.13 EMR71018.1 - 2.1 7.2 5.4 3.2 6.6 5.4 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.14 EMR71018.1 - 4.3 5.5 14.0 6.3 5.0 14.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 EMR71018.1 - 4.9 5.6 13.9 7.1 5.0 13.9 1.2 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 EMR71018.1 - 5.6 5.5 12.9 7.7 5.1 12.9 1.2 1 0 0 1 1 1 0 Hamartin protein DNA_pol_phi PF04931.13 EMR71018.1 - 6.8 4.7 15.8 11 4.0 15.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EMR71018.1 - 8.2 5.8 23.7 12 5.2 23.7 1.2 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 EMR71019.1 - 1.1e-17 64.1 2.3 0.00052 20.8 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR71019.1 - 1.5e-08 34.8 0.6 0.0022 18.2 0.1 3.1 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMR71019.1 - 1.2e-05 25.3 0.1 0.00011 22.1 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EMR71019.1 - 0.052 12.5 0.0 0.38 9.7 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MAPEG PF01124.18 EMR71020.1 - 1.2e-23 83.4 2.9 1.4e-23 83.2 2.9 1.0 1 0 0 1 1 1 1 MAPEG family Acetyltransf_1 PF00583.25 EMR71022.1 - 5.5e-14 52.4 0.0 7.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR71022.1 - 2.8e-11 43.5 0.0 4.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR71022.1 - 5.4e-10 39.6 0.0 8.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR71022.1 - 1.6e-07 31.2 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMR71022.1 - 0.012 15.7 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMR71022.1 - 0.039 14.1 0.2 0.14 12.3 0.2 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5643 PF18705.1 EMR71022.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5643) Peptidase_M14 PF00246.24 EMR71023.1 - 6.1e-69 233.0 0.0 8.1e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase PROL5-SMR PF15621.6 EMR71023.1 - 0.018 15.5 1.6 0.032 14.7 0.2 2.1 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Propep_M14 PF02244.16 EMR71023.1 - 0.022 15.2 0.0 0.066 13.6 0.0 1.9 1 0 0 1 1 1 0 Carboxypeptidase activation peptide ECR1_N PF14382.6 EMR71025.1 - 1.8e-15 56.4 0.6 4.2e-15 55.2 0.6 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EMR71025.1 - 0.00029 21.1 0.2 0.00058 20.2 0.2 1.5 1 0 0 1 1 1 1 KH domain G-alpha PF00503.20 EMR71026.1 - 4.8e-109 364.8 0.2 5.8e-109 364.5 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EMR71026.1 - 1.6e-13 50.5 0.4 1.4e-08 34.4 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMR71026.1 - 0.00012 21.5 0.2 0.015 14.6 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EMR71026.1 - 0.012 15.9 0.3 6.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EMR71026.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EMR71026.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cyt-b5 PF00173.28 EMR71027.1 - 1.1e-11 44.7 0.2 1.2e-11 44.6 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myco_19_kDa PF05481.12 EMR71027.1 - 0.16 12.2 1.9 1.1 9.6 0.3 2.2 1 1 1 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen Ribosomal_L22e PF01776.17 EMR71028.1 - 8.1e-45 151.7 1.5 1e-44 151.4 1.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family START PF01852.19 EMR71028.1 - 0.072 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 START domain SKG6 PF08693.10 EMR71029.1 - 0.039 13.4 0.4 0.095 12.1 0.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-CCCH_2 PF14608.6 EMR71030.1 - 0.77 10.3 7.7 0.27 11.8 4.0 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Glyco_hydro_3 PF00933.21 EMR71031.1 - 6e-41 140.9 0.0 1.2e-40 139.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EMR71031.1 - 2.7e-20 73.2 0.0 1.3e-16 61.2 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EMR71031.1 - 3.6e-20 71.8 0.0 8.3e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Spermine_synth PF01564.17 EMR71033.1 - 2.2e-72 242.4 0.0 3.3e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EMR71033.1 - 1.8e-24 85.4 0.1 3e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EMR71033.1 - 0.00017 22.2 0.0 0.00032 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR71033.1 - 0.011 16.5 0.6 0.048 14.4 0.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain DUF43 PF01861.16 EMR71033.1 - 0.015 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 EMR71033.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.22 EMR71034.1 - 2.2e-54 184.5 0.0 2.6e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Formyl_trans_N PF00551.19 EMR71035.1 - 2.4e-35 121.9 0.0 2.9e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase baeRF_family2 PF18844.1 EMR71035.1 - 0.019 15.1 2.0 0.078 13.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 Cofac_haem_bdg PF04187.13 EMR71035.1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Fungal_trans PF04082.18 EMR71036.1 - 1.3e-08 34.2 0.0 2.6e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1180 PF06679.12 EMR71036.1 - 0.3 11.5 6.2 0.3 11.5 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CN_hydrolase PF00795.22 EMR71038.1 - 4.8e-27 94.9 0.0 2.1e-14 53.5 0.0 2.0 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase Ran_BP1 PF00638.18 EMR71039.1 - 1.5e-13 51.1 0.0 2.7e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 EMR71039.1 - 0.00031 21.5 17.6 0.00031 21.5 17.6 11.8 4 2 6 11 11 11 4 Nucleoporin FG repeat region Aldedh PF00171.22 EMR71040.1 - 3.8e-75 253.2 0.0 4.8e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pex24p PF06398.11 EMR71041.1 - 5.2e-85 285.6 0.0 6.7e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 EMR71041.1 - 0.00057 18.4 2.5 0.068 11.5 1.7 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF3292) DUF639 PF04842.12 EMR71041.1 - 0.013 14.9 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) PRT_C PF08372.10 EMR71041.1 - 0.2 11.4 0.9 0.49 10.1 0.4 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 EMR71041.1 - 0.29 11.1 2.9 1.3 9.0 3.0 2.0 1 1 1 2 2 2 0 Reticulon SPX PF03105.19 EMR71042.1 - 1.7e-12 48.0 19.4 1.4e-08 35.1 0.0 4.1 2 1 2 4 4 4 3 SPX domain MSA-2c PF12238.8 EMR71042.1 - 0.037 14.0 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c zf-C3HC PF07967.13 EMR71042.1 - 0.076 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 C3HC zinc finger-like DUF1349 PF07081.11 EMR71042.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) Mito_fiss_reg PF05308.11 EMR71042.1 - 0.15 12.1 6.2 0.26 11.4 6.2 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF2721 PF11026.8 EMR71042.1 - 6.5 6.7 9.5 1.5 8.7 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) TPR_12 PF13424.6 EMR71043.1 - 7.2e-09 35.8 2.1 0.00074 19.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR71043.1 - 2.1e-06 27.4 1.9 0.021 14.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMR71043.1 - 7.8e-06 25.6 0.0 2 8.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMR71043.1 - 0.0015 18.3 2.2 4 7.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMR71043.1 - 0.002 18.2 2.0 7.9 7.0 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EMR71043.1 - 0.0087 15.9 1.6 5.6 7.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMR71043.1 - 0.013 16.2 0.1 18 6.1 0.3 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR71043.1 - 0.042 14.5 0.0 0.042 14.5 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMR71043.1 - 0.05 14.0 0.1 7.6 7.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR71043.1 - 0.073 13.9 0.0 34 5.6 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat SCP2 PF02036.17 EMR71044.1 - 2.1e-25 89.2 0.5 2.4e-25 89.0 0.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EMR71044.1 - 2.7e-05 24.5 0.1 3.2e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EMR71044.1 - 0.017 15.5 0.1 0.021 15.2 0.1 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain Mito_carr PF00153.27 EMR71045.1 - 5.9e-51 170.4 0.1 3.7e-16 58.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RCDG1 PF15725.5 EMR71045.1 - 0.19 12.2 1.4 3.2 8.2 0.1 2.3 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein zf-C2H2_4 PF13894.6 EMR71046.1 - 0.00018 22.1 14.4 0.0088 16.8 0.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 EMR71046.1 - 0.0021 18.4 4.2 1.2 9.6 0.0 3.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMR71046.1 - 0.011 16.0 11.3 0.087 13.1 0.2 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EMR71046.1 - 0.2 12.2 17.6 0.3 11.6 0.2 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type ATP_sub_h PF10775.9 EMR71046.1 - 0.45 10.5 2.4 20 5.2 0.2 2.5 2 0 0 2 2 2 0 ATP synthase complex subunit h GAF_2 PF13185.6 EMR71047.1 - 2.9e-09 37.4 0.0 3.7e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EMR71047.1 - 0.001 19.7 0.0 0.001 19.7 0.0 1.2 1 0 0 1 1 1 1 GAF domain AlaDh_PNT_C PF01262.21 EMR71047.1 - 0.01 15.1 0.2 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GAF_3 PF13492.6 EMR71047.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 GAF domain Glyco_hydro_76 PF03663.14 EMR71050.1 - 3.2e-19 69.7 5.4 3.5e-10 40.0 0.1 3.7 3 1 0 4 4 4 3 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMR71050.1 - 0.017 14.2 0.0 0.75 8.8 0.0 2.3 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 IMUP PF15761.5 EMR71050.1 - 0.42 11.3 5.8 1.2 9.8 5.8 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein tRNA-synt_2 PF00152.20 EMR71051.1 - 2.3e-65 220.8 0.0 2.8e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EMR71051.1 - 1.3e-06 28.1 0.0 0.00084 18.9 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 EMR71051.1 - 5.2e-05 23.2 0.0 9.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ATP-synt_F PF01990.17 EMR71051.1 - 0.056 13.8 0.0 0.83 10.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit ADK PF00406.22 EMR71054.1 - 8.2e-34 116.9 0.0 2.1e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EMR71054.1 - 5.9e-14 51.8 0.0 9.8e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EMR71054.1 - 4.6e-13 49.8 0.0 3.3e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EMR71054.1 - 2.2e-05 25.0 0.0 0.027 15.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EMR71054.1 - 0.0029 17.8 0.0 0.022 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMR71054.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4357 PF14267.6 EMR71054.1 - 0.44 10.5 2.8 0.94 9.5 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) zf-Tim10_DDP PF02953.15 EMR71055.1 - 1.4e-20 72.7 1.6 1.6e-20 72.5 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger BrkDBD PF09607.10 EMR71055.1 - 0.046 13.5 0.0 0.37 10.6 0.0 2.1 2 1 0 2 2 2 0 Brinker DNA-binding domain COesterase PF00135.28 EMR71056.1 - 5e-72 243.4 0.1 1.7e-46 159.2 0.0 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR71056.1 - 0.00019 21.4 2.8 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold ER_lumen_recept PF00810.18 EMR71059.1 - 4.7e-41 141.1 9.6 4.7e-41 141.1 9.6 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor DUF1516 PF07457.11 EMR71059.1 - 0.011 16.0 1.2 0.02 15.1 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) DUF4234 PF14018.6 EMR71059.1 - 0.059 13.5 0.7 0.059 13.5 0.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) CDC45 PF02724.14 EMR71059.1 - 0.42 8.9 4.6 0.51 8.6 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein WSC PF01822.19 EMR71060.1 - 3.6e-13 49.5 8.9 7.8e-13 48.4 8.9 1.5 1 0 0 1 1 1 1 WSC domain Abhydrolase_6 PF12697.7 EMR71060.1 - 0.0079 16.8 1.3 0.023 15.3 1.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EMR71060.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EMR71060.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 EMR71060.1 - 0.052 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EMR71060.1 - 0.053 13.1 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 EMR71060.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 EMR71060.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Porin_1 PF00267.21 EMR71061.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Gram-negative porin zf-RING_10 PF16685.5 EMR71062.1 - 1.9 8.7 5.6 10 6.4 0.1 3.4 3 0 0 3 3 3 0 zinc RING finger of MSL2 BUD22 PF09073.10 EMR71062.1 - 6.2 6.0 15.7 0.37 10.1 1.4 2.2 2 0 0 2 2 2 0 BUD22 DBP10CT PF08147.12 EMR71063.1 - 7.2e-23 80.6 0.3 2.7e-22 78.8 0.3 2.0 1 1 0 1 1 1 1 DBP10CT (NUC160) domain Mlh1_C PF16413.5 EMR71064.1 - 2.4e-98 328.8 0.0 6.4e-98 327.4 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EMR71064.1 - 5.9e-34 116.3 0.1 1.3e-33 115.2 0.1 1.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain Herpes_gI PF01688.17 EMR71064.1 - 0.19 11.7 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I RPN1_RPN2_N PF17781.1 EMR71065.1 - 3.1e-116 388.1 2.7 3.1e-116 388.1 2.7 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EMR71065.1 - 3.5e-29 100.6 0.0 6.2e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EMR71065.1 - 8.9e-21 73.2 15.1 4.2e-06 26.9 0.0 8.5 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EMR71065.1 - 8.1e-08 32.6 0.3 0.0054 17.1 0.0 3.9 3 1 1 4 4 4 3 HEAT repeats NuA4 PF09340.10 EMR71067.1 - 1.6e-22 79.1 0.2 3.2e-22 78.2 0.2 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 IATP PF04568.12 EMR71067.1 - 0.13 12.7 0.4 0.13 12.7 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF4407 PF14362.6 EMR71067.1 - 8.4 5.7 8.2 30 3.9 8.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 EMR71068.1 - 0.00057 19.6 0.4 0.00057 19.6 0.4 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FBPase PF00316.20 EMR71069.1 - 4.2e-26 91.6 0.1 2.6e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EMR71069.1 - 0.069 12.7 0.5 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 Inositol monophosphatase family IMD PF08397.11 EMR71070.1 - 2.5e-05 23.8 0.4 0.17 11.2 0.1 2.1 2 0 0 2 2 2 2 IRSp53/MIM homology domain Phage_int_SAM_2 PF12834.7 EMR71070.1 - 0.15 12.8 0.1 0.31 11.7 0.1 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal DUF1687 PF07955.11 EMR71071.1 - 3.2e-34 118.2 1.0 4.4e-34 117.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) RSB_motif PF16294.5 EMR71072.1 - 0.074 13.3 0.4 0.074 13.3 0.4 1.9 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif Zn_clus PF00172.18 EMR71073.1 - 2.2e-05 24.5 11.5 3.7e-05 23.8 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Staph_opine_DH PF10100.9 EMR71073.1 - 0.025 13.2 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase ODV-E18 PF10717.9 EMR71073.1 - 0.47 10.4 2.5 0.57 10.1 0.6 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 L51_S25_CI-B8 PF05047.16 EMR71074.1 - 3.5e-13 49.3 0.0 4.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ABC2_membrane PF01061.24 EMR71075.1 - 1.2e-76 256.9 42.8 2e-44 151.5 18.6 3.2 2 1 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EMR71075.1 - 8.7e-40 136.4 0.0 9.2e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EMR71075.1 - 3.4e-28 97.4 0.2 7e-23 80.3 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EMR71075.1 - 5.5e-09 36.5 0.1 1.7e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EMR71075.1 - 4.9e-05 23.8 0.1 0.036 14.5 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EMR71075.1 - 0.00028 21.4 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMR71075.1 - 0.00047 19.9 0.2 0.08 12.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMR71075.1 - 0.00064 19.7 0.7 0.0037 17.2 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EMR71075.1 - 0.00065 19.3 0.1 0.038 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMR71075.1 - 0.00073 19.7 0.0 0.62 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 EMR71075.1 - 0.0012 18.1 18.6 0.0012 18.1 18.6 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EMR71075.1 - 0.0021 17.9 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EMR71075.1 - 0.0054 17.0 0.4 0.8 9.9 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMR71075.1 - 0.0067 16.7 0.0 0.98 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EMR71075.1 - 0.013 15.1 1.1 2.6 7.6 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EMR71075.1 - 0.02 14.4 0.1 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EMR71075.1 - 0.057 13.3 0.3 4.3 7.2 0.3 2.5 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EMR71075.1 - 0.082 12.6 0.6 5 6.8 0.5 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMR71075.1 - 0.1 13.0 0.0 24 5.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.7 EMR71076.1 - 7.4e-10 39.3 0.0 0.028 15.0 0.0 3.7 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMR71076.1 - 1e-08 34.7 0.9 1.3 9.8 0.0 6.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 EMR71076.1 - 2e-06 28.2 1.2 0.28 11.8 0.0 5.4 3 3 3 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR71076.1 - 6.6e-05 23.1 0.4 2.2 8.7 0.0 4.4 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ribosomal_60s PF00428.19 EMR71077.1 - 0.14 12.7 5.9 0.1 13.2 2.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Seipin PF06775.14 EMR71078.1 - 3.7e-44 151.2 0.0 4.3e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Aminotran_4 PF01063.19 EMR71079.1 - 2e-33 116.1 0.0 2.5e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF1411 PF07199.11 EMR71080.1 - 0.017 14.7 1.3 0.069 12.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) SIR2 PF02146.17 EMR71081.1 - 2.2e-56 190.5 0.0 3.3e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EMR71081.1 - 0.0022 17.8 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EMR71081.1 - 0.012 15.4 0.1 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PcfK PF14058.6 EMR71082.1 - 1.3 9.3 4.7 0.23 11.7 0.5 2.2 2 2 0 2 2 2 0 PcfK-like protein Polyketide_cyc2 PF10604.9 EMR71083.1 - 3.5e-09 37.1 0.5 4.1e-09 36.8 0.5 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EMR71083.1 - 0.029 14.6 0.7 0.034 14.3 0.7 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport LBR_tudor PF09465.10 EMR71083.1 - 0.046 13.5 0.0 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain ETF_QO PF05187.13 EMR71084.1 - 6.9e-24 84.0 0.0 1.2e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EMR71084.1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf-primase PF09329.11 EMR71085.1 - 4.1e-18 64.9 1.4 7.4e-18 64.1 1.4 1.4 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.10 EMR71086.1 - 1.3e-11 44.9 9.6 8.3e-11 42.3 5.6 2.8 2 2 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain SSP160 PF06933.11 EMR71086.1 - 0.00042 18.7 6.7 0.00048 18.5 6.7 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 SVIP PF15811.5 EMR71086.1 - 0.017 15.5 5.3 0.017 15.5 5.3 2.1 2 0 0 2 2 2 0 Small VCP/p97-interacting protein BAF1_ABF1 PF04684.13 EMR71086.1 - 0.12 11.4 11.8 0.22 10.6 11.8 1.3 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FSA_C PF10479.9 EMR71086.1 - 7.9 4.5 12.3 10 4.1 12.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Beta-lactamase PF00144.24 EMR71087.1 - 1.5e-49 169.0 2.2 2.2e-49 168.5 2.2 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EMR71087.1 - 4.3e-09 36.8 0.0 9.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Caroten_synth PF04240.12 EMR71087.1 - 0.0059 16.5 1.3 0.025 14.4 1.3 1.9 1 1 1 2 2 2 1 Carotenoid biosynthesis protein FAD_binding_4 PF01565.23 EMR71088.1 - 2.6e-22 79.0 0.2 4.7e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR71088.1 - 0.00061 19.8 0.1 0.0018 18.4 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like AdoMet_MTase PF07757.13 EMR71088.1 - 0.13 12.6 0.0 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Pkinase PF00069.25 EMR71089.1 - 2.4e-08 33.7 0.0 1.7e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR71089.1 - 2e-07 30.6 0.0 5.5e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DCB PF16213.5 EMR71089.1 - 0.046 13.4 0.4 7.7 6.1 0.2 2.5 1 1 1 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF3510 PF12022.8 EMR71089.1 - 0.056 13.8 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DUF3433 PF11915.8 EMR71089.1 - 0.081 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Cys_Met_Meta_PP PF01053.20 EMR71090.1 - 4.8e-26 91.2 0.0 8.1e-26 90.4 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMR71090.1 - 0.049 12.8 0.0 0.1 11.8 0.0 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II GH131_N PF18271.1 EMR71091.1 - 7.3e-68 229.0 0.3 8.5e-68 228.8 0.3 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain TTL PF03133.15 EMR71092.1 - 2.3e-57 194.4 0.0 3.4e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EMR71092.1 - 8.9e-49 165.9 0.0 1.4e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EMR71092.1 - 0.0011 18.2 0.0 0.004 16.5 0.0 1.8 3 0 0 3 3 3 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.6 EMR71092.1 - 0.019 15.4 0.2 0.047 14.1 0.2 1.8 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EMR71092.1 - 0.027 14.5 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 efThoc1 PF11957.8 EMR71092.1 - 1.4 7.5 2.9 1.9 7.1 2.9 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Cation_ATPase_C PF00689.21 EMR71093.1 - 2.6e-41 141.4 7.1 2.6e-41 141.4 7.1 3.0 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EMR71093.1 - 8.9e-31 106.8 0.2 8.9e-31 106.8 0.2 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 EMR71093.1 - 6.4e-23 80.6 0.0 1.4e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMR71093.1 - 6.6e-22 78.8 0.0 1.4e-21 77.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMR71093.1 - 4.6e-06 26.2 0.0 1.9e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMR71093.1 - 1.6e-05 24.7 0.5 0.0002 21.2 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMR71093.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2976 PF11190.8 EMR71093.1 - 0.28 11.0 8.8 0.67 9.8 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) FCH PF00611.23 EMR71094.1 - 3.3e-16 59.3 0.9 8e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EMR71094.1 - 4.3e-12 45.4 0.0 9.7e-12 44.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMR71094.1 - 4.2e-11 42.3 0.0 7.4e-10 38.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EMR71094.1 - 5.9e-11 42.0 0.0 1.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4349 PF14257.6 EMR71094.1 - 0.092 12.2 2.2 3.5 7.0 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) ESSS PF10183.9 EMR71096.1 - 7.5e-20 71.1 0.0 9.1e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ATP-synt_E PF05680.12 EMR71096.1 - 0.041 14.2 0.0 0.099 13.0 0.0 1.6 2 0 0 2 2 2 0 ATP synthase E chain DASH_Duo1 PF08651.10 EMR71097.1 - 5.5e-20 70.9 4.9 1.6e-17 63.1 4.9 2.3 1 1 0 1 1 1 1 DASH complex subunit Duo1 DUF4047 PF13256.6 EMR71097.1 - 0.088 13.0 0.6 0.13 12.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) BRF1 PF07741.13 EMR71097.1 - 0.45 10.9 7.4 0.62 10.4 3.0 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Rrn6 PF10214.9 EMR71097.1 - 0.66 8.4 12.0 0.84 8.0 12.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RMP PF14996.6 EMR71097.1 - 1.2 9.4 4.5 8 6.7 0.1 2.1 2 0 0 2 2 2 0 Retinal Maintenance DUF4407 PF14362.6 EMR71097.1 - 2.7 7.3 7.3 3.1 7.1 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cwf_Cwc_15 PF04889.12 EMR71097.1 - 4.7 6.9 16.4 1.4 8.6 2.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3445 PF11927.8 EMR71098.1 - 3.2e-73 246.1 0.0 3.9e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Bac_rhamnosid_N PF08531.10 EMR71098.1 - 0.034 14.0 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain AMP-binding PF00501.28 EMR71099.1 - 8.1e-75 252.0 0.0 1.4e-74 251.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EMR71099.1 - 4.9e-60 202.9 0.0 1.3e-59 201.5 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EMR71099.1 - 5.5e-52 176.1 2.8 5.5e-52 176.1 2.8 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71099.1 - 2e-39 135.5 3.3 3.8e-39 134.6 3.3 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71099.1 - 4.7e-17 62.5 3.9 3.2e-14 53.2 2.2 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EMR71099.1 - 3.1e-14 53.0 1.0 4.1e-07 29.7 0.0 3.4 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR71099.1 - 1.3e-09 38.3 0.0 3.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 EMR71099.1 - 8.2e-09 35.0 1.1 0.002 17.3 0.2 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMR71099.1 - 1.6e-07 31.4 3.3 3.9e-06 26.9 1.4 3.7 5 0 0 5 5 4 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EMR71099.1 - 3e-07 29.7 0.0 2.5e-05 23.4 0.0 2.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMR71099.1 - 1.2e-06 27.9 0.3 0.0017 17.5 0.0 3.4 2 1 0 2 2 2 2 RmlD substrate binding domain AMP-binding_C PF13193.6 EMR71099.1 - 0.00013 22.9 0.4 0.00082 20.3 0.2 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 EMR71099.1 - 0.0049 16.3 0.0 3.1 7.1 0.0 2.8 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 EMR71099.1 - 0.024 14.0 0.1 0.061 12.6 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 EMR71099.1 - 0.13 12.1 1.4 0.3 10.9 1.4 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 EMR71099.1 - 0.14 11.8 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 EMR71099.1 - 1.2 8.7 3.4 38 3.7 2.0 3.1 3 0 0 3 3 3 0 NmrA-like family DUF4805 PF16063.5 EMR71099.1 - 2.1 7.6 4.9 3.7 6.8 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Aim21 PF11489.8 EMR71100.1 - 1.9e-192 642.0 78.6 1.9e-192 642.0 78.6 2.7 2 1 1 3 3 3 2 Altered inheritance of mitochondria protein 21 Rdx PF10262.9 EMR71101.1 - 8.2e-33 112.4 0.0 1.9e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Rdx family DUF3446 PF11928.8 EMR71101.1 - 0.0027 18.0 1.6 0.0027 18.0 1.6 2.3 2 0 0 2 2 2 1 Early growth response N-terminal domain NACHT PF05729.12 EMR71102.1 - 2e-07 31.1 0.0 4.8e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMR71102.1 - 2.4e-05 24.6 0.0 0.00012 22.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.7 EMR71102.1 - 0.04 14.5 0.1 7.9 7.1 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) AAA_16 PF13191.6 EMR71102.1 - 0.048 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 EMR71102.1 - 0.18 12.2 0.0 0.65 10.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Metallophos PF00149.28 EMR71103.1 - 2.4e-40 139.2 0.1 3.1e-40 138.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMR71103.1 - 5.9e-23 81.0 1.8 8.5e-23 80.5 1.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Fungal_trans PF04082.18 EMR71104.1 - 0.00018 20.7 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain VHS PF00790.19 EMR71105.1 - 2.3e-36 124.8 0.1 5.8e-36 123.4 0.1 1.7 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EMR71105.1 - 1.2e-16 60.1 0.4 2.5e-16 59.0 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EMR71105.1 - 6.3e-15 54.8 0.1 1.3e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMR71105.1 - 2e-13 49.8 0.0 4.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EMR71105.1 - 3.4e-08 33.7 1.4 8.4e-08 32.4 0.8 2.0 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EMR71105.1 - 0.0094 15.8 3.0 0.021 14.7 3.0 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF3361 PF11841.8 EMR71105.1 - 0.16 11.9 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Glyco_hydro_125 PF06824.11 EMR71106.1 - 4.8e-182 605.5 0.0 5.6e-182 605.3 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DASH_Dam1 PF08653.10 EMR71106.1 - 0.065 13.0 0.0 0.26 11.1 0.0 2.0 1 0 0 1 1 1 0 DASH complex subunit Dam1 FAD_binding_3 PF01494.19 EMR71107.1 - 2.9e-27 95.8 0.0 3.3e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMR71107.1 - 1.9e-05 23.6 0.0 2.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EMR71107.1 - 5.8e-05 23.2 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR71107.1 - 0.00055 19.2 0.0 0.00091 18.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EMR71107.1 - 0.0021 17.7 0.1 0.034 13.7 0.1 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR71107.1 - 0.0038 16.5 0.0 0.0054 16.0 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR71107.1 - 0.0076 15.5 0.1 0.022 14.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR71107.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EMR71107.1 - 0.01 14.9 0.1 0.019 14.1 0.1 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 EMR71107.1 - 0.078 13.6 0.0 0.32 11.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_18 PF00704.28 EMR71109.1 - 7.3e-51 173.8 0.5 1.3e-50 173.0 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EMR71109.1 - 1.4e-08 35.0 27.7 8.3e-06 26.2 13.3 2.6 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_43 PF04616.14 EMR71112.1 - 5.9e-26 91.5 0.2 9.4e-25 87.5 0.0 1.9 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Esterase_phd PF10503.9 EMR71113.1 - 3e-19 69.4 0.2 4.4e-19 68.9 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMR71113.1 - 3.5e-10 39.7 0.2 4.6e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EMR71113.1 - 0.014 15.0 0.1 0.014 15.0 0.1 1.8 2 0 0 2 2 2 0 Putative esterase adh_short PF00106.25 EMR71114.1 - 1.7e-18 66.8 0.0 2.3e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71114.1 - 1.3e-11 44.5 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR71114.1 - 0.0031 17.0 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR71114.1 - 0.014 15.3 0.0 0.018 14.9 0.0 1.3 1 1 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 EMR71114.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.6 1 1 0 1 1 1 0 KR domain GMC_oxred_N PF00732.19 EMR71115.1 - 7.5e-51 173.2 0.0 1e-50 172.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR71115.1 - 2.2e-37 128.7 0.0 3.9e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR71115.1 - 3.2e-05 23.2 0.1 0.00048 19.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EMR71115.1 - 3.3e-05 23.7 0.6 0.00024 20.8 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR71115.1 - 3.8e-05 23.8 0.1 0.0001 22.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR71115.1 - 0.00029 20.0 0.1 0.00043 19.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EMR71115.1 - 0.00049 19.4 0.0 0.00086 18.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EMR71115.1 - 0.0077 15.5 0.0 0.019 14.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR71115.1 - 0.015 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR71115.1 - 0.15 10.7 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DKCLD PF08068.12 EMR71116.1 - 6e-32 109.5 0.4 2e-30 104.6 0.4 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EMR71116.1 - 1.1e-23 84.3 0.1 1e-20 74.6 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EMR71116.1 - 4.1e-23 81.3 1.2 7e-23 80.5 1.2 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EMR71116.1 - 3.2e-21 75.1 1.5 6.2e-21 74.1 1.5 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EMR71116.1 - 0.026 14.8 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 UPF0113 PUA domain Med19 PF10278.9 EMR71116.1 - 1.9 8.4 9.5 3.5 7.5 9.5 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_M43 PF05572.13 EMR71117.1 - 1.2e-14 54.5 0.1 3.4e-14 53.0 0.1 1.8 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EMR71117.1 - 2.1e-05 24.8 0.1 4.1e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EMR71117.1 - 0.00096 19.7 0.2 0.0017 18.9 0.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EMR71117.1 - 0.011 15.4 3.1 0.016 14.9 3.2 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EMR71117.1 - 0.099 12.5 0.3 0.17 11.7 0.3 1.5 1 1 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 EMR71117.1 - 0.26 11.2 2.0 0.44 10.4 2.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like adh_short PF00106.25 EMR71118.1 - 1.6e-22 79.9 0.4 1.5e-20 73.5 1.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71118.1 - 7.8e-13 48.5 0.3 2.2e-11 43.8 1.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71118.1 - 4.8e-10 39.6 0.3 7.9e-10 38.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EMR71118.1 - 0.072 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DAG1 PF05454.11 EMR71119.1 - 0.00045 19.7 0.0 0.00083 18.8 0.0 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Podoplanin PF05808.11 EMR71119.1 - 0.00096 19.3 0.1 0.003 17.7 0.1 1.8 1 0 0 1 1 1 1 Podoplanin CD34_antigen PF06365.12 EMR71119.1 - 0.0027 17.3 0.2 0.0072 15.9 0.0 1.7 2 0 0 2 2 2 1 CD34/Podocalyxin family EphA2_TM PF14575.6 EMR71119.1 - 0.01 16.7 0.2 0.034 15.0 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 EMR71119.1 - 0.018 14.8 7.3 0.035 13.9 7.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 EMR71119.1 - 0.055 13.4 0.2 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family DAP10 PF07213.11 EMR71119.1 - 0.057 13.4 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 DAP10 membrane protein Insulin_TMD PF17870.1 EMR71119.1 - 0.091 12.8 0.6 0.17 12.0 0.6 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Yip1 PF04893.17 EMR71119.1 - 0.093 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain Prominin PF05478.11 EMR71119.1 - 0.28 9.1 0.0 0.36 8.7 0.0 1.1 1 0 0 1 1 1 0 Prominin TFIIA PF03153.13 EMR71119.1 - 0.37 10.8 4.6 0.54 10.2 4.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fusion_F0 PF13044.6 EMR71119.1 - 0.55 8.8 1.7 2.8 6.5 0.1 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0, Isavirus CYYR1 PF10873.8 EMR71119.1 - 2.1 8.8 7.2 18 5.8 7.2 2.5 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF3824 PF12868.7 EMR71119.1 - 8.3 7.1 16.1 0.24 12.1 7.9 2.4 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Peptidase_S8 PF00082.22 EMR71120.1 - 9.3e-09 35.0 0.1 1.4e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Subtilase family CBF PF03914.17 EMR71121.1 - 6.2e-37 127.2 1.2 8.7e-36 123.5 0.2 2.4 2 1 1 3 3 3 2 CBF/Mak21 family putAbiC PF16872.5 EMR71121.1 - 0.21 12.3 1.0 3.7 8.3 0.4 2.4 2 0 0 2 2 2 0 Putative phage abortive infection protein Mt_ATP-synt_B PF05405.14 EMR71122.1 - 4.2e-54 182.6 7.4 5.1e-54 182.3 7.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rep_trans PF02486.19 EMR71122.1 - 0.015 15.1 2.8 0.018 14.8 1.5 1.7 1 1 1 2 2 2 0 Replication initiation factor rve_3 PF13683.6 EMR71122.1 - 0.052 13.3 0.2 0.24 11.2 0.1 2.1 1 1 1 2 2 2 0 Integrase core domain Peptidase_C10 PF01640.17 EMR71122.1 - 0.11 12.8 0.3 0.14 12.5 0.3 1.3 1 0 0 1 1 1 0 Peptidase C10 family Dak2 PF02734.17 EMR71122.1 - 0.2 11.6 3.0 0.68 9.8 1.4 2.1 1 1 1 2 2 2 0 DAK2 domain adh_short_C2 PF13561.6 EMR71123.1 - 2.3e-51 174.6 0.1 2.8e-51 174.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR71123.1 - 1.1e-48 165.3 0.0 1.3e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR71123.1 - 2.6e-12 47.0 0.5 4.5e-12 46.2 0.5 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR71123.1 - 2.5e-05 23.9 0.1 9.6e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 EMR71123.1 - 0.0089 15.7 0.0 0.32 10.7 0.0 2.4 3 0 0 3 3 3 1 Starch synthase catalytic domain ADH_zinc_N PF00107.26 EMR71123.1 - 0.013 15.5 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMR71123.1 - 0.082 12.3 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mito_carr PF00153.27 EMR71124.1 - 0.0017 18.2 0.1 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial carrier protein VIT1 PF01988.19 EMR71124.1 - 0.42 10.5 4.4 1.2 9.0 4.4 1.8 1 0 0 1 1 1 0 VIT family MR_MLE_C PF13378.6 EMR71125.1 - 2e-52 177.9 0.0 2.6e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMR71125.1 - 1.1e-19 70.8 0.0 2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain NmrA PF05368.13 EMR71126.1 - 1.4e-13 51.0 0.0 1.8e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR71126.1 - 9.8e-12 45.1 0.0 2.3e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Isochorismatase PF00857.20 EMR71127.1 - 3.4e-20 72.9 0.1 2.2e-19 70.3 0.1 2.2 1 1 0 1 1 1 1 Isochorismatase family ADH_N PF08240.12 EMR71128.1 - 5.3e-24 84.2 0.1 1.1e-23 83.2 0.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR71128.1 - 7.6e-15 55.0 0.1 1.5e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR71128.1 - 1.3e-10 41.2 1.8 6.9e-08 32.2 1.8 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ApbA PF02558.16 EMR71128.1 - 0.028 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EMR71128.1 - 0.031 14.3 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LIAS_N PF16881.5 EMR71129.1 - 6.5e-18 65.1 0.1 2e-17 63.5 0.1 1.9 1 1 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EMR71129.1 - 7.1e-13 49.3 0.0 1.6e-12 48.1 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Type2_restr_D3 PF16902.5 EMR71129.1 - 0.0024 17.7 0.0 0.0088 15.9 0.0 1.9 2 0 0 2 2 2 1 Type-2 restriction enzyme D3 domain DJ-1_PfpI PF01965.24 EMR71131.1 - 1.8e-10 40.9 0.0 3.9e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMR71131.1 - 6e-07 29.4 0.0 2.3e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like adh_short PF00106.25 EMR71132.1 - 5.2e-34 117.4 0.0 1e-33 116.4 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71132.1 - 2.3e-19 69.9 0.0 3.3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71132.1 - 1.4e-06 28.4 0.1 1.9e-05 24.6 0.1 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 EMR71132.1 - 0.00029 20.4 0.0 0.004 16.6 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR71132.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 EMR71132.1 - 0.037 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EMR71132.1 - 0.13 12.6 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 EMR71133.1 - 0.00082 18.8 0.0 0.26 10.6 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR71133.1 - 0.028 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Peptidase_M36 PF02128.15 EMR71134.1 - 1.3e-159 531.4 9.5 1.4e-159 531.2 9.5 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EMR71134.1 - 0.0034 17.3 0.2 0.0088 15.9 0.0 1.8 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Sugar_tr PF00083.24 EMR71135.1 - 1.3e-19 70.4 14.0 2.9e-11 42.9 8.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR71135.1 - 4.1e-15 55.5 11.0 1.1e-07 31.2 4.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 EMR71135.1 - 0.0014 18.3 8.6 0.057 13.1 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) MFS_2 PF13347.6 EMR71135.1 - 0.0028 16.3 9.6 0.016 13.8 3.9 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein TMEM100 PF16311.5 EMR71135.1 - 0.09 12.4 0.2 0.27 10.8 0.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 LMBR1 PF04791.16 EMR71135.1 - 0.15 10.9 1.9 0.24 10.2 1.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2070 PF09843.9 EMR71135.1 - 0.21 9.8 2.8 0.31 9.3 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3021 PF11457.8 EMR71135.1 - 2.6 8.4 7.5 0.37 11.1 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Nop PF01798.18 EMR71136.1 - 2.5e-73 246.4 0.2 4.3e-73 245.6 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EMR71136.1 - 3.7e-46 156.9 2.0 3.7e-46 156.9 2.0 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain DUF3824 PF12868.7 EMR71137.1 - 0.007 17.0 2.3 0.007 17.0 2.3 6.7 3 2 3 6 6 6 4 Domain of unknwon function (DUF3824) Ligase_CoA PF00549.19 EMR71138.1 - 1.6e-24 86.5 1.1 2.9e-11 43.4 0.1 2.4 2 1 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EMR71138.1 - 0.0042 17.7 0.8 0.019 15.6 0.4 2.3 2 0 0 2 2 2 1 CoA binding domain Peripla_BP_3 PF13377.6 EMR71138.1 - 0.1 12.9 0.2 1.8 8.9 0.0 2.5 2 1 0 2 2 2 0 Periplasmic binding protein-like domain Rad60-SLD PF11976.8 EMR71139.1 - 1.8e-18 66.1 0.1 2.1e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EMR71139.1 - 1.7e-10 40.5 0.0 1.9e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family MbeB_N PF04837.12 EMR71140.1 - 0.064 13.6 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 MbeB-like, N-term conserved region DUF4545 PF15078.6 EMR71141.1 - 0.11 11.5 5.4 0.12 11.3 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) TPR_14 PF13428.6 EMR71142.1 - 1.4e-21 75.3 20.1 0.0024 18.6 0.3 10.1 9 2 3 12 12 10 7 Tetratricopeptide repeat HAT PF02184.16 EMR71142.1 - 6.1e-19 67.7 74.9 8.5e-15 54.4 1.7 12.2 15 0 0 15 15 13 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 EMR71142.1 - 3.3e-18 65.9 0.1 1e-05 25.9 0.0 6.5 5 1 0 6 6 6 3 Tetratricopeptide repeat Suf PF05843.14 EMR71142.1 - 2e-17 64.2 15.3 0.00033 20.7 0.2 6.2 4 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EMR71142.1 - 2.5e-10 40.1 13.6 0.012 14.8 2.6 5.7 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EMR71142.1 - 1.6e-09 37.5 0.7 0.0051 17.1 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR71142.1 - 9.2e-07 29.4 3.9 5.9 7.6 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMR71142.1 - 1.2e-06 28.1 12.6 1.3 9.3 0.0 7.6 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMR71142.1 - 2.2e-06 27.4 3.3 2.8 8.4 0.0 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMR71142.1 - 0.00074 20.0 14.5 23 5.9 0.1 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 EMR71142.1 - 0.0019 18.3 4.0 2.1 8.6 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat QIL1 PF15884.5 EMR71142.1 - 0.088 13.4 0.8 1.9 9.1 0.0 3.4 4 0 0 4 4 3 0 MICOS complex subunit MIC13, QIL1 ECSIT PF06239.11 EMR71142.1 - 0.17 10.9 2.6 0.34 10.0 0.0 2.4 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.6 EMR71142.1 - 0.2 12.0 13.3 3.7 7.9 0.1 6.6 8 1 0 8 8 7 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EMR71142.1 - 0.29 11.2 26.9 0.17 12.0 0.9 7.3 6 2 2 8 8 8 0 U3 small nucleolar RNA-associated protein 6 TPR_1 PF00515.28 EMR71142.1 - 1.6 8.7 4.8 58 3.7 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMR71142.1 - 2.7 8.1 6.6 25 5.1 0.3 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EMR71142.1 - 5.2 7.1 19.3 42 4.2 0.1 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat LIM PF00412.22 EMR71143.1 - 1.6e-25 89.1 20.8 1.8e-08 34.5 4.5 3.4 3 0 0 3 3 3 3 LIM domain DUF2321 PF10083.9 EMR71143.1 - 0.017 14.8 0.2 0.017 14.8 0.2 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-dskA_traR PF01258.17 EMR71143.1 - 0.097 12.6 0.3 0.097 12.6 0.3 5.7 6 1 0 6 6 6 0 Prokaryotic dksA/traR C4-type zinc finger Churchill PF06573.11 EMR71143.1 - 0.33 11.3 2.0 21 5.5 0.6 2.9 2 1 0 2 2 2 0 Churchill protein Zn-ribbon_8 PF09723.10 EMR71143.1 - 8.1 6.7 26.7 5.6 7.2 3.7 5.3 4 2 1 5 5 5 0 Zinc ribbon domain Nup84_Nup100 PF04121.13 EMR71144.1 - 6.5e-180 599.8 0.0 4.8e-177 590.3 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 TraB PF01963.17 EMR71144.1 - 0.13 12.1 0.3 20 5.0 0.1 3.0 3 0 0 3 3 3 0 TraB family Mod_r PF07200.13 EMR71145.1 - 2.4e-35 121.8 5.8 2.8e-35 121.6 5.8 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Acetate_kinase PF00871.17 EMR71147.1 - 1.1e-86 291.0 0.0 1.3e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family HLH PF00010.26 EMR71148.1 - 1.7e-12 47.1 0.0 6e-12 45.3 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 EMR71149.1 - 1.7e-17 63.4 47.5 4.9e-17 61.9 47.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily NPR3 PF03666.13 EMR71150.1 - 3.3e-144 481.2 0.0 3.3e-144 481.2 0.0 1.9 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Velvet PF11754.8 EMR71150.1 - 7.9 6.3 9.2 2.1 8.2 4.8 1.9 2 0 0 2 2 2 0 Velvet factor Lipase_GDSL_2 PF13472.6 EMR71151.1 - 3.3e-09 37.4 0.1 4.1e-09 37.1 0.1 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Amidohydro_1 PF01979.20 EMR71152.1 - 4.2e-70 236.8 0.0 9e-56 189.6 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EMR71152.1 - 2e-07 30.9 10.0 2.4e-06 27.3 2.4 2.9 1 1 1 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EMR71152.1 - 0.0023 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase SGTA_dimer PF16546.5 EMR71153.1 - 2e-24 85.1 1.1 3.2e-24 84.5 1.1 1.3 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 EMR71153.1 - 7.6e-09 35.0 5.2 0.036 14.2 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMR71153.1 - 1.2e-08 34.4 0.1 0.088 12.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMR71153.1 - 3e-06 27.8 22.2 0.00042 20.9 9.2 3.6 1 1 2 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMR71153.1 - 2.9e-05 23.7 2.7 0.046 13.4 0.3 2.9 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EMR71153.1 - 0.00037 21.1 14.2 0.4 11.6 3.1 4.3 1 1 3 4 4 4 3 Tetratricopeptide repeat BTAD PF03704.17 EMR71153.1 - 0.00042 20.8 7.9 0.16 12.4 0.0 2.8 1 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_17 PF13431.6 EMR71153.1 - 0.00047 20.4 0.9 0.1 13.0 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMR71153.1 - 0.00056 20.4 7.3 0.029 14.9 0.4 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMR71153.1 - 0.00059 19.9 2.8 0.0015 18.6 2.7 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat STI1 PF17830.1 EMR71153.1 - 0.00081 19.3 5.3 0.00081 19.3 5.3 2.3 2 0 0 2 2 2 1 STI1 domain TPR_8 PF13181.6 EMR71153.1 - 0.0059 16.7 2.0 1.4 9.4 0.1 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMR71153.1 - 0.0066 16.4 0.2 11 6.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 EMR71153.1 - 0.015 15.0 1.1 0.033 13.9 1.1 1.6 1 0 0 1 1 1 0 XPC-binding domain TPR_12 PF13424.6 EMR71153.1 - 0.05 13.9 5.8 0.086 13.1 2.4 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMR71153.1 - 0.15 12.0 6.8 0.37 10.7 1.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MGC-24 PF05283.11 EMR71153.1 - 1.5 9.3 5.8 0.48 10.9 3.1 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EHN PF06441.12 EMR71154.1 - 2.9e-19 69.4 0.0 3.2e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Pox_A_type_inc PF04508.12 EMR71154.1 - 0.035 14.0 1.4 0.12 12.2 0.4 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FAD_binding_4 PF01565.23 EMR71155.1 - 3e-17 62.6 0.3 6.4e-17 61.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain STN PF07660.14 EMR71155.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain Peptidase_S55 PF05580.12 EMR71157.1 - 0.022 14.7 0.2 0.039 13.9 0.1 1.4 1 1 0 1 1 1 0 SpoIVB peptidase S55 Ribosomal_S8 PF00410.19 EMR71158.1 - 6.6e-22 77.8 0.1 8.9e-22 77.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 TruD PF01142.18 EMR71159.1 - 8.1e-57 192.9 0.0 9.7e-51 172.9 0.0 3.8 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) XPG_I_2 PF12813.7 EMR71159.1 - 0.04 13.4 0.5 0.07 12.6 0.0 1.6 2 0 0 2 2 2 0 XPG domain containing Ribosomal_L19 PF01245.20 EMR71160.1 - 1.8e-13 50.4 0.0 3.7e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L19 Ribosomal_L7Ae PF01248.26 EMR71162.1 - 1.6e-28 98.2 1.1 2.1e-28 97.9 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EMR71162.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain ERCC3_RAD25_C PF16203.5 EMR71163.1 - 1.4e-118 394.6 0.2 2.4e-118 393.8 0.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EMR71163.1 - 2e-33 115.3 0.0 7.1e-33 113.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR71163.1 - 5e-14 52.7 0.0 1e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMR71163.1 - 1.8e-11 44.4 0.1 4.8e-11 43.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EMR71163.1 - 5.9e-08 31.8 0.0 7.3e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pyr_redox_2 PF07992.14 EMR71165.1 - 1.3e-37 129.7 0.3 1.6e-37 129.3 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR71165.1 - 1.1e-14 54.8 0.7 1.5e-10 41.5 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR71165.1 - 1.1e-05 25.2 1.5 0.03 13.9 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMR71165.1 - 0.00033 19.6 1.4 2.5 6.8 0.1 3.1 2 1 1 3 3 3 2 Tryptophan halogenase Thi4 PF01946.17 EMR71165.1 - 0.0023 17.2 0.0 0.56 9.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.12 EMR71165.1 - 0.0029 16.7 0.4 0.034 13.2 0.1 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMR71165.1 - 0.0038 17.4 0.1 0.42 10.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EMR71165.1 - 0.016 14.3 0.0 0.044 12.9 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EMR71165.1 - 0.023 14.0 0.1 1.9 7.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 EMR71165.1 - 0.043 12.9 2.8 3.7 6.5 0.3 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMR71165.1 - 0.053 12.8 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR71165.1 - 0.053 12.2 0.9 0.39 9.3 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EMR71165.1 - 0.26 10.3 3.4 3.5 6.6 0.4 2.7 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 EMR71165.1 - 0.8 9.0 3.6 4.8 6.4 0.6 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR71165.1 - 1.4 8.8 4.4 21 5.1 0.0 3.6 3 1 0 4 4 4 0 FAD-NAD(P)-binding adh_short PF00106.25 EMR71167.1 - 1.5e-43 148.6 0.0 2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71167.1 - 1.2e-30 106.9 0.0 1.6e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71167.1 - 1.6e-11 44.4 0.0 3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR71167.1 - 6.4e-07 29.1 0.0 1.6e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMR71167.1 - 1.2e-06 28.1 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EMR71167.1 - 0.0019 17.8 0.1 0.0036 16.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EMR71167.1 - 0.016 15.5 0.2 0.034 14.4 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 EMR71167.1 - 0.036 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain PALP PF00291.25 EMR71168.1 - 4.5e-67 226.5 2.1 5.3e-67 226.3 2.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SAD_SRA PF02182.17 EMR71169.1 - 8.7e-06 25.5 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain IQCJ-SCHIP1 PF15157.6 EMR71169.1 - 0.084 12.7 0.1 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Rot1 PF10681.9 EMR71169.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal adh_short PF00106.25 EMR71170.1 - 1.7e-14 53.7 0.0 4.6e-14 52.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMR71170.1 - 0.00015 21.8 0.1 0.00023 21.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMR71170.1 - 0.00034 20.3 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zinc_ribbon_12 PF11331.8 EMR71171.1 - 0.093 12.6 1.5 0.31 10.9 1.5 2.0 1 0 0 1 1 1 0 Probable zinc-ribbon domain LIM PF00412.22 EMR71171.1 - 0.25 11.6 11.8 0.54 10.5 4.1 3.2 3 0 0 3 3 3 0 LIM domain TEX29 PF15839.5 EMR71171.1 - 2.4 8.8 6.7 2.6 8.7 5.3 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 29 protein TrkH PF02386.16 EMR71172.1 - 5e-77 259.4 8.8 2.7e-76 257.0 1.7 2.1 2 0 0 2 2 2 2 Cation transport protein UIM PF02809.20 EMR71173.1 - 0.0032 17.3 11.6 0.0045 16.8 0.9 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif GldH_lipo PF14109.6 EMR71173.1 - 0.16 12.7 0.0 0.69 10.7 0.0 1.9 2 0 0 2 2 2 0 GldH lipoprotein MFS_1 PF07690.16 EMR71174.1 - 3.7e-22 78.7 24.3 3.7e-22 78.7 24.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 EMR71175.1 - 4e-31 106.6 0.0 1.5e-14 53.5 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR71175.1 - 5.8e-05 23.1 0.0 0.032 14.3 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EMR71175.1 - 0.0064 16.1 0.0 7.4 6.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EMR71175.1 - 0.03 14.3 0.3 12 5.9 0.0 3.2 3 0 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.8 EMR71175.1 - 0.04 14.0 0.1 6.6 6.9 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 DUF4783 PF16022.5 EMR71175.1 - 0.052 13.7 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) SipA_VBS PF17985.1 EMR71175.1 - 0.13 12.2 0.3 0.27 11.2 0.3 1.5 1 0 0 1 1 1 0 SipA vinculin binding site DUF4944 PF16302.5 EMR71175.1 - 0.17 11.9 0.1 25 4.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) FXMRP1_C_core PF12235.8 EMR71175.1 - 0.89 10.2 17.0 0.066 13.9 10.9 2.2 3 0 0 3 3 3 0 Fragile X-related 1 protein core C terminal FAD_binding_1 PF00667.20 EMR71177.1 - 6.8e-26 91.2 0.0 1.1e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EMR71177.1 - 3e-12 47.1 0.0 5.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ILEI PF15711.5 EMR71177.1 - 0.16 12.5 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Interleukin-like EMT inducer Cofilin_ADF PF00241.20 EMR71180.1 - 6.1e-37 126.1 0.0 7.6e-21 74.2 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PBP PF01161.20 EMR71182.1 - 1.1e-16 61.4 0.0 1.7e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-RING_2 PF13639.6 EMR71182.1 - 0.0017 18.6 1.4 0.0017 18.6 1.4 2.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMR71182.1 - 0.0036 17.1 0.9 0.0036 17.1 0.9 2.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMR71182.1 - 0.019 14.9 1.2 0.019 14.9 1.2 2.9 2 1 1 3 3 3 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EMR71182.1 - 0.039 13.8 0.6 0.039 13.8 0.6 2.7 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR71182.1 - 0.061 13.2 13.3 0.061 13.2 2.3 3.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMR71182.1 - 3.4 7.6 13.4 0.58 10.1 2.3 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 LysM PF01476.20 EMR71183.1 - 2.9e-09 36.8 0.0 5.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain DUF903 PF06004.12 EMR71183.1 - 0.038 13.9 0.3 0.038 13.9 0.3 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) Sugar_tr PF00083.24 EMR71184.1 - 4.5e-90 302.7 21.6 5.1e-90 302.5 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR71184.1 - 3.1e-40 138.2 25.0 3.1e-40 138.2 25.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR71184.1 - 0.00025 19.6 0.9 0.00025 19.6 0.9 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EMR71184.1 - 0.0014 17.5 15.3 0.081 11.8 5.0 2.5 2 1 0 2 2 2 2 MFS_1 like family Mito_carr PF00153.27 EMR71185.1 - 9.2e-68 224.2 1.8 8e-22 77.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TauE PF01925.19 EMR71186.1 - 0.016 14.9 0.2 0.019 14.6 0.2 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF4199 PF13858.6 EMR71186.1 - 0.077 13.4 0.0 0.09 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Mito_carr PF00153.27 EMR71187.1 - 6.5e-16 58.0 0.3 3.2e-09 36.6 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein Methyltransf_23 PF13489.6 EMR71188.1 - 7.5e-10 38.9 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR71188.1 - 6.1e-05 23.7 0.0 0.00022 21.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR71188.1 - 0.00015 22.4 0.1 0.0022 18.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR71188.1 - 0.0053 17.4 0.0 0.024 15.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR71188.1 - 0.055 13.3 0.0 2.6 7.8 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain MARVEL PF01284.23 EMR71189.1 - 5e-05 23.4 10.7 8.9e-05 22.6 10.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain Zip PF02535.22 EMR71189.1 - 0.077 12.2 1.2 0.1 11.8 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_88 PF07470.13 EMR71190.1 - 8.2e-07 28.4 1.6 1.7e-06 27.3 1.5 1.7 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Urocanase_N PF17391.2 EMR71190.1 - 0.14 11.8 0.1 17 5.1 0.0 3.0 3 1 0 3 3 3 0 Urocanase N-terminal domain AAA_16 PF13191.6 EMR71191.1 - 1.4e-07 32.1 0.4 7.3e-07 29.7 0.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EMR71191.1 - 3.5e-05 23.8 0.6 0.00013 22.0 0.6 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EMR71191.1 - 0.0019 18.5 1.1 0.0067 16.7 0.3 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EMR71191.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EMR71191.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EMR71191.1 - 0.017 15.5 0.3 0.16 12.4 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EMR71191.1 - 0.051 12.9 1.4 0.052 12.9 0.1 1.6 2 0 0 2 2 2 0 KaiC DUF815 PF05673.13 EMR71191.1 - 0.074 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EMR71191.1 - 0.094 12.6 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 NTPase DUF1246 PF06849.12 EMR71191.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1246) AAA_19 PF13245.6 EMR71191.1 - 1.2 9.4 4.6 1.6 9.1 0.2 2.7 2 1 0 2 2 2 0 AAA domain KASH_CCD PF14662.6 EMR71192.1 - 0.11 12.3 1.3 6.9 6.5 0.0 2.9 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH SAP PF02037.27 EMR71192.1 - 0.12 12.2 0.1 0.33 10.8 0.1 1.8 1 0 0 1 1 1 0 SAP domain DinI PF06183.13 EMR71192.1 - 0.34 11.3 1.7 2.2 8.6 0.2 2.6 2 0 0 2 2 2 0 DinI-like family LrgB PF04172.16 EMR71193.1 - 1.1e-30 106.8 8.6 4.2e-22 78.7 0.2 2.0 2 0 0 2 2 2 2 LrgB-like family DUF228 PF02989.14 EMR71193.1 - 0.044 13.6 0.4 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 Lyme disease proteins of unknown function Peptidase_S8 PF00082.22 EMR71194.1 - 1.3e-24 87.0 3.4 1.9e-24 86.4 3.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR71194.1 - 1.7e-10 41.4 0.0 2.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DNA_pol_P_Exo PF18049.1 EMR71194.1 - 0.23 10.9 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo DUF3818 PF12825.7 EMR71195.1 - 6.2e-41 140.5 0.6 1.1e-23 83.8 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EMR71195.1 - 2.2e-12 47.1 0.0 3.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 PX-associated DUF3944 PF13099.6 EMR71195.1 - 0.082 12.8 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) DUF4476 PF14771.6 EMR71195.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Rotamase PF00639.21 EMR71196.1 - 4e-23 82.2 0.1 9.7e-23 81.0 0.0 1.6 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EMR71196.1 - 3.5e-18 66.2 0.0 4.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EMR71196.1 - 5.1e-08 32.9 1.7 6e-08 32.6 0.5 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EMR71196.1 - 4.6e-05 24.3 0.0 7.7e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 EMR71196.1 - 0.0025 17.5 0.2 0.004 16.8 0.2 1.4 1 0 0 1 1 1 1 WW domain PI-PLC-C1 PF16670.5 EMR71197.1 - 8.6e-127 422.7 0.0 1e-126 422.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent MARVEL PF01284.23 EMR71197.1 - 2.7e-12 46.9 7.4 2.7e-12 46.9 6.3 1.5 1 1 0 1 1 1 1 Membrane-associating domain Glyco_hydro_47 PF01532.20 EMR71198.1 - 5.3e-163 543.2 0.0 6.1e-163 543.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.32 EMR71199.1 - 4.8e-38 128.5 10.7 6.1e-07 30.0 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR71199.1 - 3.7e-10 39.9 1.3 0.038 14.3 0.0 4.5 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMR71199.1 - 4.8e-09 35.4 3.3 0.21 10.2 0.0 4.4 3 1 1 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.7 EMR71199.1 - 0.0012 18.7 0.2 0.0029 17.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 EMR71199.1 - 0.0023 17.3 0.1 0.0043 16.4 0.1 1.4 1 0 0 1 1 1 1 WD40-like domain F-box PF00646.33 EMR71199.1 - 0.0044 16.9 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 EMR71199.1 - 0.031 13.2 1.4 4.1 6.2 0.1 3.4 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain AATase PF07247.12 EMR71200.1 - 6.9e-13 48.0 0.0 1.9e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase S10_plectin PF03501.15 EMR71201.1 - 5.5e-42 141.8 0.1 6.7e-42 141.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.12 EMR71202.1 - 5.4e-28 97.1 1.2 1.1e-27 96.1 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR71202.1 - 1.8e-15 57.1 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR71202.1 - 4e-10 39.5 0.0 5.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMR71202.1 - 1.5e-08 35.8 0.0 2.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EMR71202.1 - 0.00013 21.3 0.1 0.00021 20.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 EMR71202.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EMR71202.1 - 0.14 11.5 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 ThiF family Sde2_N_Ubi PF13019.6 EMR71203.1 - 6.3e-70 234.3 0.3 9.3e-70 233.7 0.3 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain His_Phos_1 PF00300.22 EMR71203.1 - 0.066 12.9 3.1 0.11 12.2 3.1 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) RRN3 PF05327.11 EMR71203.1 - 0.62 8.5 3.4 0.81 8.2 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RCR PF12273.8 EMR71204.1 - 0.00021 22.0 22.0 0.007 17.0 22.0 2.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Sugar_tr PF00083.24 EMR71205.1 - 2.4e-114 382.7 20.8 3.8e-114 382.0 20.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR71205.1 - 3.3e-29 101.9 42.2 3.6e-26 91.9 29.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp PF00026.23 EMR71205.1 - 4.3e-17 62.5 0.0 1.3e-16 60.9 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Tht1 PF04163.12 EMR71205.1 - 0.32 9.7 0.1 0.49 9.1 0.1 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein zf-C2H2 PF00096.26 EMR71206.1 - 0.46 11.0 12.7 24 5.7 0.1 5.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type VWA_CoxE PF05762.14 EMR71209.1 - 0.21 11.0 0.1 0.32 10.4 0.1 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein zf-tcix PF14952.6 EMR71209.1 - 2.4 7.9 9.3 0.17 11.5 0.3 3.0 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding AMP-binding PF00501.28 EMR71211.1 - 3.2e-31 108.4 0.0 5.8e-16 58.1 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EMR71211.1 - 1.4e-06 29.2 0.1 2.3e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phosphodiest PF01663.22 EMR71212.1 - 1.1e-15 58.1 1.9 3e-09 37.0 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMR71212.1 - 0.02 14.3 0.1 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Sulfatase DUF2207 PF09972.9 EMR71212.1 - 0.11 11.2 1.3 0.4 9.4 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Alpha-amylase PF00128.24 EMR71213.1 - 1.2e-48 166.4 1.9 1.6e-31 110.1 3.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF1966 PF09260.11 EMR71213.1 - 0.0036 17.6 0.3 0.011 15.9 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1966) Cellulase PF00150.18 EMR71213.1 - 0.015 14.7 0.1 0.062 12.7 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) GHL6 PF14871.6 EMR71213.1 - 0.038 14.1 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 hDGE_amylase PF14701.6 EMR71213.1 - 0.07 12.2 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Aminotran_5 PF00266.19 EMR71213.1 - 0.077 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class-V NHL PF01436.21 EMR71213.1 - 0.2 11.8 0.7 1 9.5 0.1 2.4 2 0 0 2 2 2 0 NHL repeat Lipase_GDSL_2 PF13472.6 EMR71214.1 - 5.6e-18 66.0 0.0 8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMR71214.1 - 0.0025 17.8 0.0 0.0049 16.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EMR71214.1 - 0.0032 17.6 0.1 0.052 13.7 0.1 2.5 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family RRM_1 PF00076.22 EMR71215.1 - 5.3e-59 196.0 0.0 2.9e-18 65.4 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EMR71215.1 - 9.2e-08 32.0 2.5 0.099 12.4 0.2 4.1 2 2 2 4 4 4 2 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 EMR71215.1 - 7.6e-07 29.5 0.0 2.8 8.1 0.0 6.1 5 2 2 7 7 7 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 EMR71215.1 - 0.0001 22.3 0.0 2 8.6 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif Nop14 PF04147.12 EMR71215.1 - 0.022 13.0 25.1 0.057 11.6 25.1 1.6 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EMR71215.1 - 0.051 11.9 19.9 0.15 10.3 19.9 1.7 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 EMR71215.1 - 3.1 6.5 7.6 6.6 5.5 7.6 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Dynactin_p62 PF05502.13 EMR71215.1 - 8 5.1 8.4 15 4.2 8.4 1.4 1 0 0 1 1 1 0 Dynactin p62 family Glyco_transf_22 PF03901.17 EMR71216.1 - 8.3e-43 147.2 14.7 3e-33 115.7 9.7 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.6 EMR71216.1 - 0.012 15.8 6.8 0.015 15.5 5.6 1.8 1 1 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase BBE PF08031.12 EMR71217.1 - 0.015 15.4 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Berberine and berberine like COesterase PF00135.28 EMR71219.1 - 9.9e-94 315.0 0.0 1.2e-93 314.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR71219.1 - 4.2e-05 23.5 1.0 0.0003 20.7 0.2 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_M14 PF00246.24 EMR71220.1 - 2.1e-73 247.7 0.1 2.5e-73 247.4 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Acetyltransf_10 PF13673.7 EMR71222.1 - 8.5e-11 41.9 0.0 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR71222.1 - 2.4e-10 40.7 0.0 2.8e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR71222.1 - 3.2e-07 30.7 0.0 4.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.22 EMR71223.1 - 1.3e-27 96.7 0.0 1e-17 64.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 APH PF01636.23 EMR71224.1 - 4.1e-07 30.2 0.0 1.6e-06 28.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EMR71224.1 - 2.8e-05 23.6 0.0 0.00021 20.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EMR71224.1 - 0.0002 21.0 0.3 0.00045 19.9 0.3 1.5 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 EMR71224.1 - 0.0014 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EMR71224.1 - 0.0042 16.4 0.0 0.028 13.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 EMR71224.1 - 0.0072 16.0 0.1 0.0086 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Glyco_hydro_98M PF08306.11 EMR71224.1 - 0.039 13.3 0.8 4.7 6.4 0.1 2.0 1 1 1 2 2 2 0 Glycosyl hydrolase family 98 Haspin_kinase PF12330.8 EMR71224.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Abhydrolase_6 PF12697.7 EMR71226.1 - 1.7 9.2 7.5 4.1 7.9 6.4 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family AA_permease_2 PF13520.6 EMR71227.1 - 1.6e-60 205.2 49.5 1.9e-60 204.9 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR71227.1 - 2.7e-33 115.3 42.5 3.5e-33 114.9 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_2 PF07992.14 EMR71228.1 - 3e-18 66.1 0.1 2.6e-17 63.0 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR71228.1 - 5.1e-05 22.7 10.1 0.0067 15.7 0.2 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR71228.1 - 5.2e-05 22.5 0.7 0.0024 17.0 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EMR71228.1 - 0.00062 18.6 0.9 0.0038 16.0 0.2 2.2 1 1 1 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EMR71228.1 - 0.0019 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR71228.1 - 0.004 16.8 0.0 0.11 12.0 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR71228.1 - 0.0049 16.9 0.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 EMR71228.1 - 0.019 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EMR71228.1 - 0.022 13.8 3.3 0.19 10.7 1.5 2.2 1 1 1 2 2 2 0 Lycopene cyclase protein adh_short PF00106.25 EMR71229.1 - 3.2e-16 59.4 0.0 1.1e-12 47.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71229.1 - 2.6e-09 37.0 0.0 1.9e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71229.1 - 0.0046 16.9 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain tRNA-synt_1 PF00133.22 EMR71230.1 - 2.8e-178 593.9 0.8 2.8e-177 590.6 0.7 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMR71230.1 - 4.6e-18 65.6 0.0 1.4e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMR71230.1 - 2.7e-12 46.2 1.1 1.3e-06 27.5 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (M) SpoIIID PF12116.8 EMR71231.1 - 0.2 11.8 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D Peptidase_M43 PF05572.13 EMR71232.1 - 8.7e-15 54.9 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EMR71232.1 - 0.0013 18.9 1.0 0.0029 17.8 1.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EMR71232.1 - 0.0072 16.8 0.0 0.015 15.8 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like p450 PF00067.22 EMR71233.1 - 6.7e-36 124.0 0.0 9.4e-34 116.9 0.0 2.7 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EMR71234.1 - 8.5e-20 71.0 39.4 8.5e-20 71.0 39.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PMT PF02366.18 EMR71235.1 - 3.1e-82 275.9 17.7 4.5e-82 275.3 17.7 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMR71235.1 - 1.7e-38 132.3 4.1 2.2e-33 115.5 0.8 4.1 2 2 0 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMR71235.1 - 2.4e-21 76.4 1.1 3.5e-21 75.9 1.1 1.2 1 0 0 1 1 1 1 MIR domain RAMP4 PF06624.12 EMR71235.1 - 0.038 14.0 0.8 1.7 8.8 0.5 2.8 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Lum_binding PF00677.17 EMR71236.1 - 5.6e-44 148.0 3.6 2.1e-21 75.7 0.5 2.1 2 0 0 2 2 2 2 Lumazine binding domain FeoA PF04023.14 EMR71236.1 - 0.12 12.7 1.4 17 5.7 0.2 3.5 2 1 1 3 3 3 0 FeoA domain Bac_luciferase PF00296.20 EMR71237.1 - 1.7e-60 205.1 3.7 3.1e-60 204.2 3.7 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase ERCC4 PF02732.15 EMR71238.1 - 4.4e-24 85.4 0.2 6.3e-24 85.0 0.2 1.2 1 0 0 1 1 1 1 ERCC4 domain Sugar_tr PF00083.24 EMR71239.1 - 5.6e-62 210.1 22.8 6.9e-62 209.8 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR71239.1 - 3.2e-15 55.9 35.1 6.9e-15 54.8 31.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR71239.1 - 0.0055 15.3 23.7 0.075 11.6 9.0 3.4 2 2 2 4 4 4 2 MFS/sugar transport protein DUF872 PF05915.12 EMR71239.1 - 0.034 14.3 0.1 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Cytochrom_B_C PF00032.17 EMR71239.1 - 0.13 12.5 4.4 11 6.3 0.0 3.5 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Ureide_permease PF07168.11 EMR71239.1 - 0.17 10.6 8.4 0.49 9.1 4.3 2.3 2 0 0 2 2 2 0 Ureide permease PhoD PF09423.10 EMR71240.1 - 7.7e-97 324.4 3.3 2.1e-96 323.0 3.3 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EMR71240.1 - 7.4e-31 106.6 0.2 1.5e-30 105.5 0.2 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EMR71240.1 - 0.00011 22.7 0.4 0.00029 21.3 0.4 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Ribonuc_L-PSP PF01042.21 EMR71241.1 - 6.2e-40 136.0 0.0 8.2e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Methyltransf_25 PF13649.6 EMR71242.1 - 1.1e-11 45.3 0.0 3.1e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EMR71242.1 - 2.2e-11 43.7 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EMR71242.1 - 3.4e-10 39.9 0.0 8.5e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR71242.1 - 6.4e-09 36.4 0.0 2.3e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EMR71242.1 - 4.7e-08 32.3 0.1 6.8e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 EMR71242.1 - 8e-06 25.8 0.0 2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EMR71242.1 - 2.9e-05 24.1 0.1 5.1e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMR71242.1 - 4.5e-05 22.9 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EMR71242.1 - 5.3e-05 22.8 0.0 8.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EMR71242.1 - 0.00014 22.5 0.0 0.00029 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EMR71242.1 - 0.00026 20.9 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 EMR71242.1 - 0.0018 18.1 0.3 0.003 17.4 0.3 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EMR71242.1 - 0.0021 18.2 0.0 0.0042 17.2 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EMR71242.1 - 0.0097 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EMR71242.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.20 EMR71242.1 - 0.024 13.7 0.2 0.076 12.1 0.1 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase DNA_pol_B_palm PF14792.6 EMR71243.1 - 6.5e-35 119.8 0.0 1.3e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EMR71243.1 - 1.7e-23 82.5 0.2 3.3e-23 81.6 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EMR71243.1 - 9.8e-21 73.3 0.1 2.8e-20 71.9 0.1 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EMR71243.1 - 2.4e-13 50.2 0.6 8.1e-13 48.5 0.2 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 EMR71243.1 - 0.0031 17.7 0.0 5.9 7.2 0.0 3.0 1 1 2 3 3 3 2 Pathogenicity locus NTP_transf_2 PF01909.23 EMR71243.1 - 0.012 15.8 0.1 0.035 14.4 0.1 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.6 EMR71243.1 - 0.054 14.1 0.1 4.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain Ammonium_transp PF00909.21 EMR71245.1 - 2.3e-115 385.5 28.2 2.6e-115 385.3 28.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PGM_PMM_I PF02878.16 EMR71246.1 - 1.5e-16 60.4 0.4 3.6e-07 30.0 0.1 2.9 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EMR71246.1 - 4.9e-11 42.7 0.2 2.2e-10 40.5 0.2 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EMR71246.1 - 4.3e-05 23.7 0.0 0.00026 21.1 0.0 2.4 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EMR71246.1 - 0.0018 18.8 0.2 0.041 14.5 0.1 3.2 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MFS_1 PF07690.16 EMR71247.1 - 4e-13 49.0 8.3 4e-13 49.0 8.3 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Per1 PF04080.13 EMR71248.1 - 2.5e-103 345.3 14.5 3e-103 345.0 14.5 1.1 1 0 0 1 1 1 1 Per1-like family DUF3522 PF12036.8 EMR71248.1 - 0.0031 17.8 10.3 0.0059 16.9 10.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) HAV_VP PF12944.7 EMR71251.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP NPR1_interact PF15699.5 EMR71251.1 - 1.4 9.5 5.0 0.32 11.6 0.8 2.1 2 1 0 2 2 2 0 NPR1 interacting zf-C2H2 PF00096.26 EMR71252.1 - 0.0042 17.5 2.8 0.0042 17.5 2.8 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EMR71252.1 - 0.097 12.5 11.2 0.058 13.2 1.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 EMR71252.1 - 0.95 9.6 4.8 3.1 7.9 2.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EMR71252.1 - 1.5 9.9 18.9 0.17 12.8 2.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger PEP_mutase PF13714.6 EMR71253.1 - 4.7e-40 137.5 0.2 5.4e-40 137.3 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EMR71253.1 - 1.9e-17 63.0 0.2 2.4e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF4267 PF14087.6 EMR71254.1 - 1.3e-29 102.5 8.4 4.2e-29 100.9 8.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) NAD_synthase PF02540.17 EMR71254.1 - 0.11 11.5 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 NAD synthase Aconitase PF00330.20 EMR71255.1 - 7.4e-68 229.6 0.0 6.1e-66 223.3 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) NB-ARC PF00931.22 EMR71256.1 - 7.9e-08 31.8 0.0 8.2e-07 28.5 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EMR71256.1 - 0.0007 19.9 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR71256.1 - 0.0071 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EMR71256.1 - 0.19 11.8 0.1 0.61 10.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Transket_pyr PF02779.24 EMR71260.1 - 6.7e-46 156.2 0.0 9.8e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMR71260.1 - 4.2e-36 123.5 0.1 1.6e-35 121.7 0.1 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain PTR2 PF00854.21 EMR71261.1 - 2e-44 152.0 1.3 2.9e-44 151.5 1.3 1.2 1 0 0 1 1 1 1 POT family AA_permease_2 PF13520.6 EMR71262.1 - 2.1e-37 129.0 43.5 2.4e-37 128.8 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR71262.1 - 4.7e-16 58.5 32.8 6.3e-16 58.0 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease Gly_transf_sug PF04488.15 EMR71263.1 - 2.7e-09 37.5 0.0 5.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EMR71263.1 - 0.0054 16.2 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Aldedh PF00171.22 EMR71264.1 - 9.9e-179 594.7 0.8 1.1e-178 594.5 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EMR71264.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family GAIN PF16489.5 EMR71264.1 - 0.023 14.1 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain DUF1487 PF07368.11 EMR71264.1 - 0.21 11.0 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Glucosaminidase PF01832.20 EMR71265.1 - 0.032 14.7 0.1 0.34 11.4 0.0 2.4 2 1 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Abhydrolase_3 PF07859.13 EMR71266.1 - 4.7e-17 62.6 0.0 7.1e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 EMR71266.1 - 0.00093 18.0 0.0 0.0069 15.1 0.0 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EMR71266.1 - 0.0041 16.6 0.0 0.98 8.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF3245 PF11595.8 EMR71266.1 - 2.7 8.5 5.2 4.1 7.9 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Oxysterol_BP PF01237.18 EMR71268.1 - 4.7e-90 302.1 0.0 1.2e-87 294.2 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein zf-CCCH PF00642.24 EMR71269.1 - 1.3e-08 34.6 18.9 3e-07 30.2 2.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EMR71269.1 - 0.0042 16.9 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EMR71269.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 EMR71269.1 - 0.017 15.8 3.6 0.44 11.3 0.2 2.4 2 0 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 EMR71269.1 - 0.18 12.1 4.2 0.22 11.8 0.3 2.3 2 1 0 2 2 2 0 Zinc-finger containing family PAXNEB PF05625.11 EMR71270.1 - 1.8e-98 330.1 0.0 2.1e-98 329.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein MCD_N PF17408.2 EMR71270.1 - 0.028 14.5 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain RRM_1 PF00076.22 EMR71272.1 - 1.7e-24 85.4 0.2 1.1e-11 44.3 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMR71272.1 - 0.0029 17.4 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EMR71272.1 - 0.0072 15.9 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EMR71272.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) RRM_8 PF11835.8 EMR71272.1 - 0.11 12.8 0.0 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 RRM-like domain RRM_1 PF00076.22 EMR71274.1 - 3.4e-31 106.9 0.0 1.6e-14 53.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EMR71274.1 - 0.0022 17.6 1.4 0.37 10.5 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 EMR71274.1 - 0.018 14.7 0.0 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR71274.1 - 0.084 13.0 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif CMV_1a_C PF12503.8 EMR71274.1 - 0.14 12.2 0.1 5.9 7.0 0.1 2.5 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal Hexapep PF00132.24 EMR71275.1 - 4.5e-16 57.9 23.9 2.3e-10 39.8 2.7 3.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMR71275.1 - 3.2e-06 26.8 12.6 8.2e-06 25.5 2.8 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EMR71275.1 - 0.00036 18.8 0.2 0.0022 16.2 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) SRR1 PF07985.12 EMR71276.1 - 0.0013 18.8 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 SRR1 SQS_PSY PF00494.19 EMR71277.1 - 2.7e-34 118.9 0.0 4.3e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase AXE1 PF05448.12 EMR71278.1 - 4.4e-05 22.3 0.1 0.00037 19.3 0.1 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 EMR71278.1 - 0.005 16.4 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 EMR71278.1 - 0.066 12.9 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 EMR71278.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Aa_trans PF01490.18 EMR71279.1 - 1e-43 149.6 34.1 1.2e-43 149.3 34.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SH3_9 PF14604.6 EMR71280.1 - 8.7e-27 92.7 3.5 1.7e-12 47.0 0.2 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EMR71280.1 - 4.6e-24 83.8 4.9 3e-11 42.8 0.3 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EMR71280.1 - 5.6e-16 58.0 0.1 9.1e-08 31.7 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 EMR71280.1 - 3.6e-14 52.6 0.0 7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-H2C2_2 PF13465.6 EMR71281.1 - 4e-06 27.0 1.1 4e-06 27.0 1.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EMR71281.1 - 2.3e-05 24.6 9.8 3e-05 24.2 0.3 3.4 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EMR71281.1 - 3.3e-05 23.8 0.5 0.073 13.1 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EMR71281.1 - 0.00039 21.0 12.6 0.18 12.4 0.0 4.1 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EMR71281.1 - 0.0061 17.3 7.5 0.015 16.1 0.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EMR71281.1 - 0.51 10.1 1.9 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain HET PF06985.11 EMR71283.1 - 2.2e-10 41.1 10.9 6.7e-08 33.0 4.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Choline_kinase PF01633.20 EMR71285.1 - 1.7e-27 96.4 0.0 2.2e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase HAD_2 PF13419.6 EMR71287.1 - 2e-24 86.7 0.0 2.5e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR71287.1 - 5.2e-14 53.0 0.0 1.5e-13 51.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR71287.1 - 2.7e-05 24.2 0.0 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 EMR71287.1 - 8.7e-05 23.0 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EMR71287.1 - 0.0079 16.3 0.0 0.022 14.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Radical_SAM PF04055.21 EMR71287.1 - 0.1 13.0 0.0 0.39 11.1 0.0 1.9 1 1 0 1 1 1 0 Radical SAM superfamily MutS_V PF00488.21 EMR71288.1 - 1.5e-47 162.1 0.0 2.9e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMR71288.1 - 0.00018 21.8 0.2 0.00057 20.2 0.0 1.8 2 1 0 2 2 2 1 MutS domain III Calreticulin PF00262.18 EMR71289.1 - 1.1e-158 527.9 34.8 1.8e-158 527.2 26.2 2.4 2 1 0 2 2 2 1 Calreticulin family SLT PF01464.20 EMR71290.1 - 0.02 14.6 0.5 0.057 13.1 0.5 1.9 1 1 0 1 1 1 0 Transglycosylase SLT domain INTAP PF16617.5 EMR71290.1 - 0.18 12.2 3.9 0.38 11.1 3.9 1.6 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region Proteasome PF00227.26 EMR71291.1 - 2.8e-46 157.4 0.1 3.3e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Acetyltransf_1 PF00583.25 EMR71292.1 - 1.9e-09 37.8 0.3 3e-09 37.1 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR71292.1 - 3.7e-09 36.9 0.0 6.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR71292.1 - 6e-08 32.7 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR71292.1 - 0.00022 21.1 0.4 0.0007 19.5 0.4 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EMR71292.1 - 0.0075 16.9 0.1 0.047 14.4 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain p450 PF00067.22 EMR71293.1 - 1.4e-72 245.0 0.0 3.2e-72 243.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Aldolase_II PF00596.21 EMR71294.1 - 6.9e-42 143.5 0.0 8.2e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain zf-Tim10_DDP PF02953.15 EMR71295.1 - 0.24 11.1 7.5 0.25 11.0 1.7 2.8 3 0 0 3 3 3 0 Tim10/DDP family zinc finger CorA PF01544.18 EMR71296.1 - 3.2e-12 46.4 1.1 8.6e-11 41.7 0.2 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SURF6 PF04935.12 EMR71296.1 - 0.35 10.7 5.6 0.73 9.6 5.6 1.5 1 0 0 1 1 1 0 Surfeit locus protein 6 MMgT PF10270.9 EMR71297.1 - 3.5e-38 130.0 0.0 4.3e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter FAD_binding_4 PF01565.23 EMR71298.1 - 6.8e-24 84.2 3.3 1.3e-23 83.3 3.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR71298.1 - 0.069 13.3 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Peptidase_M22 PF00814.25 EMR71299.1 - 1.8e-09 37.7 0.0 3.9e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Glycoprotease family Myc_N PF01056.18 EMR71299.1 - 0.0035 17.3 1.2 0.0046 16.9 1.2 1.2 1 0 0 1 1 1 1 Myc amino-terminal region FGGY_C PF02782.16 EMR71299.1 - 0.087 12.5 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain UPF0565 PF10561.9 EMR71299.1 - 0.087 12.0 0.5 0.11 11.7 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 ORC4_C PF14629.6 EMR71299.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF5520 PF17658.1 EMR71299.1 - 0.14 11.2 2.3 0.19 10.8 2.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) NOA36 PF06524.12 EMR71299.1 - 1.6 8.0 11.0 2.3 7.4 11.0 1.1 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 EMR71300.1 - 6.3e-22 78.0 63.8 2.2e-17 63.0 27.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR71300.1 - 1.4e-06 27.1 24.8 1.8e-06 26.7 23.0 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UDPGT PF00201.18 EMR71300.1 - 0.023 13.5 0.0 0.053 12.3 0.0 1.5 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Orf78 PF06024.12 EMR71300.1 - 0.14 12.4 0.9 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) AAA_12 PF13087.6 EMR71302.1 - 2e-35 122.2 0.0 3.5e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMR71302.1 - 8.8e-27 94.5 1.2 1.5e-25 90.5 1.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR71302.1 - 1.1e-11 45.3 0.0 3.2e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EMR71302.1 - 1e-10 41.7 0.2 4.2e-08 33.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EMR71302.1 - 0.00016 21.7 0.6 0.00044 20.3 0.2 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EMR71302.1 - 0.00085 18.9 3.2 0.0093 15.5 3.2 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 EMR71302.1 - 0.0051 16.6 0.8 0.0082 15.9 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 EMR71302.1 - 0.0058 16.1 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 EMR71302.1 - 0.027 14.7 0.1 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EMR71302.1 - 0.036 13.3 0.0 0.036 13.3 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EMR71302.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DnaB_C PF03796.15 EMR71302.1 - 0.097 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase PF06745.13 EMR71302.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 EMR71302.1 - 0.13 12.2 0.0 0.81 9.6 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase DNA_primase_lrg PF04104.14 EMR71303.1 - 5.6e-78 262.0 0.0 8.7e-78 261.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF1571 PF07608.11 EMR71303.1 - 0.11 11.9 0.3 0.2 11.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) Phage_TTP_13 PF16463.5 EMR71304.1 - 0.015 14.8 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Phage tail tube protein family EIF_2_alpha PF07541.12 EMR71305.1 - 7.4e-33 113.1 0.0 1.5e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EMR71305.1 - 1.1e-12 48.1 0.6 2.3e-12 47.1 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain GRDA PF04723.14 EMR71305.1 - 0.44 10.3 3.5 0.78 9.5 3.5 1.3 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A FAD-oxidase_C PF02913.19 EMR71307.1 - 4.1e-60 203.5 0.0 5.7e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMR71307.1 - 2.2e-36 124.6 0.5 4e-36 123.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain ADH_N PF08240.12 EMR71308.1 - 4.9e-25 87.5 2.8 8.2e-25 86.8 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR71308.1 - 2.9e-13 49.9 0.0 9.9e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMR71308.1 - 0.0024 17.3 0.2 0.0042 16.5 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR71308.1 - 0.0056 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-Tim10_DDP PF02953.15 EMR71309.1 - 8.7e-24 83.0 1.3 1.1e-23 82.6 1.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger WD40 PF00400.32 EMR71310.1 - 1.3e-31 108.1 12.8 3.2e-06 27.8 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EMR71310.1 - 5.9e-10 38.9 0.3 1.2e-09 37.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EMR71310.1 - 8.4e-09 35.6 1.7 0.004 17.4 0.0 5.8 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EMR71310.1 - 1.4e-07 31.2 0.0 2.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EMR71310.1 - 4.4e-06 25.6 0.1 0.23 10.1 0.0 3.7 2 1 1 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EMR71310.1 - 0.0016 18.4 1.1 21 5.2 0.0 4.7 4 2 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region FlaG PF03646.15 EMR71310.1 - 0.018 15.2 0.2 3.4 7.9 0.0 4.1 6 0 0 6 6 6 0 FlaG protein Cytochrom_D1 PF02239.16 EMR71310.1 - 0.042 12.4 0.0 0.093 11.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain PQQ PF01011.21 EMR71310.1 - 0.045 13.7 0.0 1.4 9.0 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat ANTH PF07651.16 EMR71311.1 - 1.8e-66 224.0 0.7 2.3e-66 223.6 0.7 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EMR71311.1 - 3.3e-07 30.4 0.0 5.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ENTH domain TFIIA PF03153.13 EMR71311.1 - 1 9.3 27.9 1.4 8.8 27.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAT1 PF06391.13 EMR71312.1 - 3.3e-29 102.2 9.5 4.4e-29 101.8 9.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EMR71312.1 - 1.5e-24 85.6 7.5 2.2e-24 85.1 7.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMR71312.1 - 0.003 17.4 5.4 0.006 16.4 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR71312.1 - 0.011 15.6 5.8 0.017 15.0 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SWIRM-assoc_2 PF16496.5 EMR71312.1 - 0.012 14.6 0.4 0.017 14.0 0.4 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal zf-RING_5 PF14634.6 EMR71312.1 - 0.082 12.9 9.8 0.37 10.8 10.0 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 EMR71312.1 - 0.11 12.8 6.0 0.2 12.0 6.0 1.4 1 0 0 1 1 1 0 Ring finger domain Phage_Mu_F PF04233.14 EMR71312.1 - 0.13 13.0 0.1 0.13 13.0 0.1 2.6 3 1 1 4 4 4 0 Phage Mu protein F like protein Zn_ribbon_17 PF17120.5 EMR71312.1 - 0.15 11.7 4.8 0.37 10.5 4.8 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EMR71312.1 - 0.19 11.8 5.6 0.33 11.0 5.6 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMR71312.1 - 0.51 10.2 7.6 1.6 8.6 7.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EMR71312.1 - 2.5 8.3 5.6 1.2 9.3 2.9 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger tRNA-synt_2 PF00152.20 EMR71313.1 - 2e-81 273.5 0.0 4.2e-81 272.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EMR71313.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) CS PF04969.16 EMR71314.1 - 4.8e-20 72.3 0.0 1.9e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 CS domain Prefoldin_3 PF13758.6 EMR71315.1 - 9.2e-28 96.2 2.1 9.2e-28 96.2 2.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 EMR71315.1 - 1.8e-23 83.2 0.6 1.8e-23 83.2 0.6 5.3 5 1 1 6 6 6 1 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.20 EMR71315.1 - 0.0011 18.9 5.3 0.31 11.0 0.5 2.9 2 0 0 2 2 2 2 Prefoldin subunit TFR_dimer PF04253.15 EMR71315.1 - 0.043 13.9 0.8 0.25 11.4 0.3 2.4 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Prefoldin PF02996.17 EMR71315.1 - 0.091 12.7 5.3 4.7 7.2 0.5 2.9 2 1 1 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.12 EMR71315.1 - 0.16 12.4 2.5 5.1 7.6 0.1 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EMR71315.1 - 0.22 11.5 1.7 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EMR71315.1 - 0.3 11.2 2.0 18 5.5 0.2 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4298 PF14131.6 EMR71315.1 - 0.39 10.7 4.5 0.2 11.6 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) ABC_tran_CTD PF16326.5 EMR71315.1 - 0.83 9.9 15.2 0.4 11.0 0.3 3.5 3 0 0 3 3 2 0 ABC transporter C-terminal domain CytochromB561_N PF09786.9 EMR71315.1 - 1.9 7.4 9.6 0.19 10.7 0.6 2.2 2 0 0 2 2 2 0 Cytochrome B561, N terminal Csm1_N PF18504.1 EMR71315.1 - 2.2 8.7 8.7 1.6 9.2 0.2 3.8 3 1 1 4 4 4 0 Csm1 N-terminal domain zf-CCCH PF00642.24 EMR71316.1 - 0.012 15.5 1.9 0.012 15.5 1.9 3.9 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EMR71316.1 - 0.39 11.4 0.1 0.39 11.4 0.1 2.6 3 0 0 3 3 3 0 Torus domain GTP_EFTU PF00009.27 EMR71317.1 - 1.1e-33 116.4 4.9 3.2e-32 111.7 4.9 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EMR71317.1 - 3.8e-27 94.5 0.0 9.9e-27 93.1 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EMR71317.1 - 2.2e-10 40.6 0.4 6.3e-10 39.1 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR71317.1 - 9.2e-06 25.7 1.7 0.0005 20.0 0.1 2.4 1 1 1 2 2 2 1 RsgA GTPase IF2_N PF04760.15 EMR71317.1 - 6.8e-05 22.6 0.1 0.00018 21.3 0.1 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.21 EMR71317.1 - 0.00085 18.8 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 EMR71317.1 - 0.0013 19.1 0.7 3.4 8.1 0.0 3.0 2 1 0 2 2 2 2 Elongation factor Tu domain 2 SRPRB PF09439.10 EMR71317.1 - 0.0017 17.8 0.2 0.0042 16.5 0.2 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EMR71317.1 - 0.0032 17.0 0.4 0.01 15.4 0.4 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 EMR71317.1 - 0.0055 16.5 0.2 0.016 15.0 0.2 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EMR71317.1 - 0.0058 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF3854 PF12965.7 EMR71317.1 - 0.0069 16.4 0.1 0.022 14.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3854) MMR_HSR1_Xtn PF16897.5 EMR71317.1 - 0.05 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU_D4 PF14578.6 EMR71317.1 - 0.25 11.3 3.5 0.24 11.3 0.2 2.5 3 0 0 3 3 3 0 Elongation factor Tu domain 4 TPR_19 PF14559.6 EMR71318.1 - 1.9e-09 37.9 2.4 0.00024 21.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR71318.1 - 1e-07 31.5 13.9 0.11 12.7 0.0 7.4 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMR71318.1 - 1.1e-07 31.3 5.3 0.11 12.4 0.0 5.8 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMR71318.1 - 6.8e-06 25.9 0.4 14 6.2 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMR71318.1 - 9.3e-06 25.8 8.7 0.057 13.7 0.4 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMR71318.1 - 1.8e-05 24.4 0.0 0.002 18.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EMR71318.1 - 0.0056 17.2 1.4 3 8.7 0.1 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMR71318.1 - 0.006 17.3 13.4 2.2 9.3 0.1 7.2 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMR71318.1 - 0.018 14.8 3.8 19 5.0 0.0 5.0 6 1 0 6 6 6 0 TPR repeat YwqJ-deaminase PF14431.6 EMR71318.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 YwqJ-like deaminase TPR_10 PF13374.6 EMR71318.1 - 0.14 12.1 4.3 4 7.4 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat NAD_binding_9 PF13454.6 EMR71319.1 - 1.3e-46 158.5 0.0 2.5e-46 157.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding p450 PF00067.22 EMR71320.1 - 9e-22 77.4 0.0 1.2e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 EMR71321.1 - 1e-46 159.4 0.0 1.2e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR71321.1 - 1.9e-25 89.8 0.1 2.9e-25 89.2 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR71321.1 - 2.2e-07 30.6 0.0 3.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR71321.1 - 0.0013 17.8 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EMR71321.1 - 0.076 13.6 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 EMR71321.1 - 0.12 11.8 0.1 0.46 9.8 0.0 2.0 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase ABC_tran PF00005.27 EMR71322.1 - 7.7e-49 165.7 0.0 3.1e-24 86.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EMR71322.1 - 5.4e-48 163.2 34.9 3.1e-28 98.7 8.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 EMR71322.1 - 2.2e-10 40.8 8.5 0.0061 16.4 0.0 4.5 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMR71322.1 - 3e-09 36.7 0.4 0.0053 16.2 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMR71322.1 - 8.8e-08 31.8 1.6 0.0069 16.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EMR71322.1 - 2.4e-07 31.5 1.0 0.0038 17.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMR71322.1 - 2.4e-07 31.3 2.3 0.016 15.6 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 EMR71322.1 - 4.9e-07 30.1 0.1 0.072 13.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EMR71322.1 - 5.4e-07 29.7 3.1 0.012 15.6 0.3 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EMR71322.1 - 6e-06 26.1 0.3 0.012 15.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EMR71322.1 - 2.3e-05 24.4 0.1 0.095 12.6 0.1 2.5 2 0 0 2 2 2 2 NACHT domain T2SSE PF00437.20 EMR71322.1 - 7.3e-05 21.9 1.0 0.087 11.9 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_28 PF13521.6 EMR71322.1 - 0.0001 22.6 3.0 0.049 13.9 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.6 EMR71322.1 - 0.00034 21.0 0.3 0.061 13.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EMR71322.1 - 0.00055 19.9 0.0 0.81 9.6 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea cobW PF02492.19 EMR71322.1 - 0.00061 19.4 3.1 0.23 11.0 0.5 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EMR71322.1 - 0.00075 19.1 0.2 0.57 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EMR71322.1 - 0.0011 19.3 0.2 3.5 8.0 0.0 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMR71322.1 - 0.0012 19.4 0.0 2.6 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMR71322.1 - 0.002 18.2 1.4 4.9 7.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EMR71322.1 - 0.0028 17.5 0.4 0.6 9.8 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 EMR71322.1 - 0.0037 17.2 0.6 0.61 10.0 0.0 3.6 4 0 0 4 4 4 1 NTPase SbcCD_C PF13558.6 EMR71322.1 - 0.0043 17.2 1.2 3.3 8.0 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit KAP_NTPase PF07693.14 EMR71322.1 - 0.0043 16.3 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain AAA_33 PF13671.6 EMR71322.1 - 0.0045 17.2 0.1 3.4 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EMR71322.1 - 0.0057 16.4 0.3 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMR71322.1 - 0.0057 17.0 0.1 2.6 8.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 EMR71322.1 - 0.0062 16.5 0.7 1 9.4 0.1 3.0 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 EMR71322.1 - 0.0064 16.2 0.8 4.3 7.0 0.0 3.4 4 0 0 4 4 3 0 AAA ATPase domain MobB PF03205.14 EMR71322.1 - 0.012 15.5 0.7 1.7 8.6 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 EMR71322.1 - 0.015 15.5 0.1 7 6.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 EMR71322.1 - 0.015 15.7 0.1 0.89 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EMR71322.1 - 0.021 14.9 2.3 5.3 7.2 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PDR_CDR PF06422.12 EMR71322.1 - 0.023 14.6 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 CDR ABC transporter FtsK_SpoIIIE PF01580.18 EMR71322.1 - 0.025 13.9 2.6 3.8 6.8 0.4 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 EMR71322.1 - 0.031 13.7 1.1 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_7 PF12775.7 EMR71322.1 - 0.034 13.6 0.5 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 EMR71322.1 - 0.047 13.3 1.5 5.2 6.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EMR71322.1 - 0.048 12.9 0.7 1.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 EMR71322.1 - 0.049 13.4 0.2 3.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.16 EMR71322.1 - 0.049 13.1 0.4 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 EMR71322.1 - 0.052 13.3 0.2 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EMR71322.1 - 0.061 12.6 0.2 9.9 5.3 0.1 2.2 2 0 0 2 2 2 0 Septin Vfa1 PF08432.10 EMR71322.1 - 0.082 13.2 0.2 0.22 11.8 0.0 1.6 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 DnaB_C PF03796.15 EMR71322.1 - 0.085 12.2 0.3 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Dynamin_N PF00350.23 EMR71322.1 - 0.096 12.7 0.3 9.3 6.3 0.0 2.8 2 0 0 2 2 2 0 Dynamin family Cytidylate_kin PF02224.18 EMR71322.1 - 0.099 12.4 1.5 3.5 7.3 0.1 2.7 3 0 0 3 3 2 0 Cytidylate kinase G-alpha PF00503.20 EMR71322.1 - 0.12 11.5 0.2 7.5 5.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_35 PF14516.6 EMR71322.1 - 0.12 11.2 0.1 12 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain ABC_ATPase PF09818.9 EMR71322.1 - 0.13 11.1 0.1 4.8 5.9 0.1 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class PduV-EutP PF10662.9 EMR71322.1 - 0.14 11.9 0.4 8.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribo_biogen_C PF04034.13 EMR71323.1 - 1.5e-48 163.7 0.0 2e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EMR71323.1 - 1.8e-12 46.8 0.9 4.3e-12 45.6 0.9 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 EMR71323.1 - 0.039 13.3 18.8 0.066 12.5 18.8 1.3 1 0 0 1 1 1 0 BUD22 DUF4874 PF16173.5 EMR71324.1 - 1.5e-11 44.2 0.0 2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) DUF4832 PF16116.5 EMR71324.1 - 0.047 13.5 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) TPR_21 PF09976.9 EMR71324.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain FAD_binding_4 PF01565.23 EMR71325.1 - 1.4e-18 67.0 0.1 2.5e-17 62.9 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR71325.1 - 0.016 15.3 0.0 0.043 13.9 0.0 1.7 2 0 0 2 2 2 0 Berberine and berberine like TPR_17 PF13431.6 EMR71326.1 - 0.17 12.3 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Plasmodium_Vir PF05795.11 EMR71326.1 - 0.19 11.1 5.7 0.23 10.8 5.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4215 PF13948.6 EMR71326.1 - 4.7 7.7 9.8 7.8 7.0 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) Endomucin PF07010.12 EMR71326.1 - 9.8 6.1 34.8 22 4.9 33.8 1.9 2 0 0 2 2 2 0 Endomucin Acyl_transf_3 PF01757.22 EMR71327.1 - 2.5e-24 86.0 31.1 4.2e-24 85.3 31.1 1.4 1 1 0 1 1 1 1 Acyltransferase family VHS PF00790.19 EMR71328.1 - 7.1e-45 152.3 0.1 2.6e-44 150.5 0.0 1.9 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 EMR71328.1 - 3.3e-21 75.7 0.3 5.6e-21 74.9 0.3 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 EMR71328.1 - 7.4e-18 64.6 2.7 8.5e-18 64.4 0.0 2.5 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 EMR71328.1 - 8e-08 31.8 0.1 2.4e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 GGA N-GAT domain DUF3328 PF11807.8 EMR71329.1 - 3.4e-18 66.3 1.7 4.3e-18 65.9 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Oest_recep PF02159.15 EMR71329.1 - 0.19 12.2 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Oestrogen receptor NMO PF03060.15 EMR71330.1 - 1.6e-30 106.7 10.1 1.3e-29 103.7 10.1 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EMR71330.1 - 1.1e-07 31.2 0.2 5.2e-06 25.7 0.2 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMR71330.1 - 2.8e-06 26.7 0.4 4.4e-06 26.1 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 EMR71330.1 - 6e-06 25.5 5.1 8.8e-06 25.0 5.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Methyltransf_20 PF12147.8 EMR71330.1 - 0.056 12.6 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PP1c_bdg PF10488.9 EMR71331.1 - 0.0031 17.0 1.8 0.0033 17.0 1.8 1.1 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region CENP-B_dimeris PF09026.10 EMR71331.1 - 0.013 15.9 11.3 0.018 15.4 11.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain KIND PF16474.5 EMR71331.1 - 0.11 12.4 5.9 0.13 12.1 5.9 1.1 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Sigma70_ner PF04546.13 EMR71331.1 - 0.14 12.0 7.7 0.16 11.8 7.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 EMR71331.1 - 0.3 9.1 7.7 0.3 9.1 7.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GOLD_2 PF13897.6 EMR71331.1 - 0.39 11.2 5.5 0.55 10.7 5.5 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CENP-T_N PF16171.5 EMR71331.1 - 0.41 9.5 3.0 0.47 9.3 3.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus HSP90 PF00183.18 EMR71331.1 - 0.53 9.1 7.9 0.6 8.9 7.9 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF2457 PF10446.9 EMR71331.1 - 1.6 7.8 13.9 1.8 7.7 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 EMR71331.1 - 1.9 6.6 12.5 1.8 6.6 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 EMR71331.1 - 2 7.6 6.2 2 7.6 6.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 EMR71331.1 - 2.2 6.5 8.6 2.2 6.5 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EMR71331.1 - 2.2 6.3 14.6 2.5 6.1 14.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 EMR71331.1 - 7.3 5.5 10.2 8.1 5.4 10.2 1.1 1 0 0 1 1 1 0 Pes-10 NOG1 PF06858.14 EMR71332.1 - 0.41 10.5 1.2 0.64 9.8 0.1 1.8 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) FMN_dh PF01070.18 EMR71333.1 - 5.8e-85 285.4 1.7 4.6e-51 173.9 0.4 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 EMR71333.1 - 2.8e-06 26.6 0.6 4.2e-06 26.0 0.6 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMR71333.1 - 0.00017 21.1 1.2 0.00027 20.4 0.8 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EMR71333.1 - 0.018 14.2 0.2 0.051 12.7 0.2 1.6 1 1 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 EMR71333.1 - 0.031 13.5 1.2 2.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EMR71333.1 - 0.07 12.6 1.1 2.3 7.6 0.2 2.5 2 1 1 3 3 3 0 Histidine biosynthesis protein MatE PF01554.18 EMR71334.1 - 4.9e-54 182.3 28.6 2.6e-37 127.9 9.5 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EMR71334.1 - 0.00012 22.1 0.7 0.00012 22.1 0.7 4.3 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Como_SCP PF02248.16 EMR71334.1 - 0.096 12.2 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Small coat protein Methyltransf_33 PF10017.9 EMR71335.1 - 1e-78 264.6 0.0 1.2e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent SRCR PF00530.18 EMR71335.1 - 0.0088 16.5 1.5 0.028 14.9 1.0 2.1 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF995 PF06191.12 EMR71335.1 - 0.16 11.7 0.9 0.26 11.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Fungal_trans PF04082.18 EMR71336.1 - 3.2e-09 36.2 0.0 3.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EMR71338.1 - 3.3e-22 78.9 0.1 1.2e-21 77.1 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71338.1 - 6.2e-13 48.8 0.3 1.7e-12 47.4 0.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71338.1 - 0.00045 20.2 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DJ-1_PfpI PF01965.24 EMR71340.1 - 3.2e-16 59.6 0.0 1.2e-15 57.7 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMR71340.1 - 6.9e-08 32.4 0.0 5.8e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 EMR71340.1 - 0.0023 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 EMR71341.1 - 6.7e-32 110.8 21.1 1.1e-31 110.1 21.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_N PF08240.12 EMR71342.1 - 1.4e-10 41.0 0.1 4.6e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR71342.1 - 1.6e-09 37.8 0.1 3.4e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 EMR71344.1 - 0.044 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain AMP-binding PF00501.28 EMR71346.1 - 0 1581.1 0.2 4.3e-74 249.6 0.0 9.1 7 2 1 8 8 8 8 AMP-binding enzyme Condensation PF00668.20 EMR71346.1 - 0 1198.3 0.0 6.9e-57 193.1 0.0 12.2 10 2 1 11 11 11 11 Condensation domain PP-binding PF00550.25 EMR71346.1 - 5.7e-96 314.9 1.0 4.1e-12 46.3 0.0 7.8 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EMR71346.1 - 1.1e-06 29.5 0.0 15 6.7 0.0 7.0 7 0 0 7 7 7 1 AMP-binding enzyme C-terminal domain Phage_C PF12025.8 EMR71346.1 - 0.013 15.3 0.1 8.9 6.3 0.0 2.8 2 0 0 2 2 2 0 Phage protein C MFS_1 PF07690.16 EMR71347.1 - 9.9e-18 64.2 31.5 1.2e-17 63.9 31.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4079 PF13301.6 EMR71348.1 - 1.1 9.4 7.9 1.7 8.8 6.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) MFS_1 PF07690.16 EMR71349.1 - 2.7e-43 148.3 49.1 2.7e-43 148.3 49.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily eIF2A PF08662.11 EMR71350.1 - 6e-78 261.2 0.0 1.4e-76 256.7 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EMR71350.1 - 0.00053 20.7 0.8 3.9 8.5 0.1 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.12 EMR71350.1 - 0.037 14.0 0.5 47 4.1 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 EMR71350.1 - 1.4 8.7 3.8 29 4.5 0.1 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature CDV3 PF15359.6 EMR71350.1 - 6.8 7.2 14.0 1.7 9.1 0.1 2.9 2 1 0 2 2 2 0 Carnitine deficiency-associated protein 3 PP28 PF10252.9 EMR71351.1 - 1.5e-28 99.0 20.0 1.5e-28 99.0 20.0 3.2 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 YL1 PF05764.13 EMR71351.1 - 0.024 14.8 48.8 0.03 14.4 48.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein GMC_oxred_C PF05199.13 EMR71352.1 - 1.4e-36 126.2 0.0 2.1e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR71352.1 - 1.2e-24 87.2 0.0 1.7e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DUF1996 PF09362.10 EMR71353.1 - 1.6e-71 241.0 0.5 2.2e-71 240.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Podoplanin PF05808.11 EMR71354.1 - 9.8e-06 25.8 0.4 2.2e-05 24.6 0.4 1.5 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 EMR71354.1 - 0.0021 17.0 0.8 0.0028 16.6 0.8 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 EMR71354.1 - 0.87 9.0 7.6 2.4 7.6 7.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Methyltransf_2 PF00891.18 EMR71355.1 - 4.2e-30 104.6 0.0 8.8e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain DUF3328 PF11807.8 EMR71355.1 - 4.6e-10 39.6 0.9 1e-09 38.5 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_25 PF13649.6 EMR71355.1 - 0.008 16.9 0.0 0.036 14.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain HTH_AsnC-type PF13404.6 EMR71355.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.16 EMR71355.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 MTS PF05175.14 EMR71355.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Staphostatin_B PF09023.10 EMR71356.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Staphostatin B Chromate_transp PF02417.15 EMR71357.1 - 5.1e-54 182.7 33.4 1.9e-32 112.6 13.6 2.4 3 0 0 3 3 3 2 Chromate transporter Asparaginase PF00710.20 EMR71358.1 - 8e-53 178.8 0.2 1.1e-52 178.4 0.2 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EMR71358.1 - 2.4e-17 63.2 0.0 1.1e-16 61.0 0.0 2.1 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Aa_trans PF01490.18 EMR71360.1 - 1.1e-74 251.6 29.9 1.3e-74 251.3 29.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein EFTUD2 PF16004.5 EMR71360.1 - 0.099 13.2 0.6 0.19 12.3 0.6 1.3 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus tRNA-synt_2c PF01411.19 EMR71361.1 - 3.8e-06 25.7 0.1 4.7e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EMR71361.1 - 7.9e-06 25.9 0.8 2.1e-05 24.5 0.8 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain ABC_tran PF00005.27 EMR71362.1 - 4.5e-34 117.9 0.0 1.2e-33 116.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EMR71362.1 - 3.8e-31 108.7 15.9 5.4e-31 108.3 15.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EMR71362.1 - 3.4e-05 23.4 0.9 0.0028 17.1 0.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMR71362.1 - 0.0013 18.6 0.2 0.076 12.8 0.0 2.9 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMR71362.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR71362.1 - 0.0023 18.2 0.9 0.02 15.2 0.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMR71362.1 - 0.0027 17.4 0.1 0.0069 16.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMR71362.1 - 0.0047 17.3 0.4 0.038 14.4 0.9 2.2 2 1 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMR71362.1 - 0.015 15.2 0.0 0.045 13.7 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 EMR71362.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMR71362.1 - 0.096 11.9 0.1 0.65 9.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin G-alpha PF00503.20 EMR71362.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 EMR71362.1 - 0.14 12.5 0.4 1.1 9.5 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Glyco_hydro_12 PF01670.16 EMR71363.1 - 4.6e-59 200.0 5.6 5.3e-59 199.8 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 p450 PF00067.22 EMR71364.1 - 1.7e-68 231.5 0.0 2e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1376 PF07120.11 EMR71364.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) Amidohydro_1 PF01979.20 EMR71365.1 - 1.3e-24 87.2 0.0 5.7e-23 81.8 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR71365.1 - 7.7e-13 48.7 0.0 7.5e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Methyltransf_33 PF10017.9 EMR71366.1 - 4.9e-80 269.0 0.0 5.9e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Preseq_ALAS PF09029.10 EMR71367.1 - 0.00049 20.6 5.5 0.13 12.7 5.5 2.7 1 1 0 1 1 1 1 5-aminolevulinate synthase presequence MMR_HSR1 PF01926.23 EMR71368.1 - 1.8e-10 40.9 0.7 3.7e-10 39.9 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EMR71368.1 - 2.6e-06 26.9 0.1 2.6e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 EMR71368.1 - 3.8e-05 23.1 0.6 6.6e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.23 EMR71368.1 - 0.00029 21.0 4.3 0.3 11.1 0.0 3.3 2 1 1 3 3 3 2 Dynamin family FeoB_N PF02421.18 EMR71368.1 - 0.00043 19.9 0.1 0.0008 19.0 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF4460 PF14687.6 EMR71368.1 - 0.0018 18.3 0.0 0.0057 16.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) NB-ARC PF00931.22 EMR71368.1 - 0.0045 16.2 0.5 0.0094 15.2 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain CtIP_N PF10482.9 EMR71368.1 - 0.0055 16.7 3.6 0.011 15.7 3.6 1.5 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain RsgA_GTPase PF03193.16 EMR71368.1 - 0.006 16.5 0.4 0.023 14.6 0.4 2.1 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EMR71368.1 - 0.0086 16.4 0.2 0.039 14.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EMR71368.1 - 0.0091 16.5 0.5 0.021 15.4 0.0 1.9 2 1 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 EMR71368.1 - 0.011 15.9 0.1 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMR71368.1 - 0.018 15.6 0.4 0.077 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EMR71368.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EMR71368.1 - 0.02 14.5 0.3 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Clathrin_lg_ch PF01086.17 EMR71368.1 - 0.032 14.3 4.1 0.067 13.2 4.1 1.5 1 0 0 1 1 1 0 Clathrin light chain DUF87 PF01935.17 EMR71368.1 - 0.073 13.2 7.6 0.44 10.6 0.7 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 EMR71368.1 - 0.077 12.8 0.5 0.077 12.8 0.5 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EMR71368.1 - 0.093 13.1 1.4 0.25 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EMR71368.1 - 0.12 11.9 0.6 0.48 10.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 EMR71368.1 - 0.19 11.2 1.5 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RICH PF05062.12 EMR71368.1 - 0.31 11.4 0.2 0.31 11.4 0.2 2.8 3 0 0 3 3 3 0 RICH domain IIGP PF05049.13 EMR71368.1 - 0.37 9.8 3.6 1.2 8.2 0.1 2.4 2 1 1 3 3 3 0 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 EMR71368.1 - 1.2 8.6 3.6 9.2 5.7 0.8 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran_Xtn PF12848.7 EMR71368.1 - 1.3 9.1 7.9 2.6 8.1 7.5 1.7 1 1 0 1 1 1 0 ABC transporter dNK PF01712.19 EMR71368.1 - 1.4 8.7 4.6 5.8 6.7 0.1 3.0 2 1 1 3 3 3 0 Deoxynucleoside kinase DUF1690 PF07956.11 EMR71368.1 - 3.4 8.1 7.2 8.8 6.8 7.2 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Cytochrom_C_2 PF01322.20 EMR71368.1 - 6.1 7.8 8.6 48 4.9 0.1 2.8 1 1 1 2 2 2 0 Cytochrome C' SUIM_assoc PF16619.5 EMR71369.1 - 0.041 14.0 3.7 0.36 10.9 1.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3575 PF12099.8 EMR71370.1 - 0.14 11.4 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) Ank_2 PF12796.7 EMR71372.1 - 9.7e-61 202.3 0.1 5.3e-08 33.3 0.0 7.3 6 1 1 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR71372.1 - 2.3e-38 130.0 3.9 1.9e-05 25.1 0.0 11.6 6 4 9 15 15 15 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR71372.1 - 3.3e-37 126.0 16.8 3.1e-05 24.2 0.1 12.1 7 5 8 15 15 15 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR71372.1 - 1.9e-36 120.0 9.3 0.0011 19.2 0.0 15.4 16 0 0 16 16 16 8 Ankyrin repeat Ank PF00023.30 EMR71372.1 - 4.9e-32 109.0 9.6 0.0061 16.9 0.0 13.8 15 0 0 15 15 15 9 Ankyrin repeat DUF3447 PF11929.8 EMR71372.1 - 0.0025 17.7 0.0 8.5 6.4 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) NUDIX PF00293.28 EMR71373.1 - 4.2e-13 49.5 0.0 6.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EMR71373.1 - 0.0011 19.0 0.1 0.0043 17.0 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Serglycin PF04360.12 EMR71373.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Serglycin adh_short PF00106.25 EMR71374.1 - 2.6e-27 95.6 0.0 3.9e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71374.1 - 6.5e-26 91.3 0.0 9.6e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71374.1 - 4.2e-05 23.5 2.6 0.0011 18.9 0.6 2.1 2 0 0 2 2 2 2 KR domain Eno-Rase_NADH_b PF12242.8 EMR71374.1 - 0.027 14.2 0.3 0.63 9.8 0.5 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 EMR71374.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2524 PF10732.9 EMR71375.1 - 0.087 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Glyco_hydro_49N PF17433.2 EMR71376.1 - 4.7e-62 209.0 2.5 1.4e-61 207.5 2.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain Glyco_hydro_49 PF03718.13 EMR71376.1 - 3.9e-23 81.7 2.2 4.6e-23 81.4 0.7 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 IPU_b_solenoid PF18783.1 EMR71376.1 - 1.2e-21 76.4 2.5 3.2e-21 75.1 2.5 1.8 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat B_solenoid_dext PF18841.1 EMR71376.1 - 1e-16 60.9 7.9 1.2e-16 60.7 5.6 2.5 2 0 0 2 2 2 1 Beta solenoid repeat from Dextranase ADH_zinc_N PF00107.26 EMR71377.1 - 1.7e-23 83.0 0.0 2.9e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR71377.1 - 1.6e-07 32.4 0.0 2.5e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR71377.1 - 7e-07 28.9 0.1 8.4e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_3 PF03447.16 EMR71377.1 - 0.028 15.0 1.1 0.047 14.3 0.1 1.8 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain SIR2 PF02146.17 EMR71378.1 - 4.9e-36 124.3 0.0 9.4e-36 123.4 0.0 1.5 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EMR71378.1 - 0.00067 19.4 0.1 0.0018 18.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain COX5B PF01215.19 EMR71379.1 - 1.8e-57 192.6 0.0 2.3e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb NapD PF03927.13 EMR71380.1 - 0.0085 16.1 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 NapD protein SKA2 PF16740.5 EMR71380.1 - 0.42 10.4 5.4 1.2 8.9 5.4 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Cep57_CLD_2 PF14197.6 EMR71380.1 - 1 9.5 10.4 2.7 8.2 10.4 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF724 PF05266.14 EMR71380.1 - 3.8 7.3 7.6 2.2 8.1 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spc24 PF08286.11 EMR71380.1 - 8 6.8 8.1 14 6.0 6.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 GGACT PF06094.12 EMR71381.1 - 2.2e-12 47.6 0.0 3.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Aldo_ket_red PF00248.21 EMR71382.1 - 3.2e-33 115.2 0.0 2e-23 83.0 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Ras PF00071.22 EMR71385.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Ras family SOBP PF15279.6 EMR71385.1 - 0.029 15.0 5.2 0.05 14.2 5.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein F-box PF00646.33 EMR71385.1 - 0.03 14.2 0.1 0.067 13.1 0.1 1.6 1 0 0 1 1 1 0 F-box domain DUF3915 PF13054.6 EMR71385.1 - 1.4 8.9 9.3 2.9 7.9 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) His_Phos_2 PF00328.22 EMR71386.1 - 3.5e-28 99.0 0.0 4.6e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 EMR71387.1 - 8.1e-22 77.8 0.0 8.4e-17 61.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR71387.1 - 7.7e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_11 PF08241.12 EMR71389.1 - 1.1e-15 58.1 0.0 2.7e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR71389.1 - 1.3e-15 57.9 0.0 3.3e-15 56.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR71389.1 - 1e-13 51.4 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR71389.1 - 1.6e-11 44.3 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR71389.1 - 9.1e-11 41.5 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMR71389.1 - 3.9e-09 37.1 0.0 8.3e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EMR71389.1 - 0.01 15.4 0.0 0.21 11.1 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase small domain MetW PF07021.12 EMR71389.1 - 0.051 13.2 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Diphthamide_syn PF01866.17 EMR71390.1 - 1.8e-116 388.8 0.0 2.2e-116 388.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Glyco_hydro_35 PF01301.19 EMR71392.1 - 9.5e-88 294.8 2.7 2.4e-87 293.5 2.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EMR71392.1 - 1.2e-56 191.4 1.2 2.2e-56 190.6 1.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EMR71392.1 - 2.2e-48 163.6 3.2 3e-29 101.9 0.0 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EMR71392.1 - 5e-26 90.1 0.1 1.1e-25 89.0 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 EMR71392.1 - 2.3e-07 30.5 2.7 1.9e-05 24.2 1.5 2.9 1 1 1 2 2 2 1 Beta-galactosidase Cellulase PF00150.18 EMR71392.1 - 0.00085 18.8 1.9 0.001 18.6 0.6 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_6 PF12697.7 EMR71393.1 - 3.1e-07 31.2 1.5 3.1e-07 31.2 1.5 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR71393.1 - 0.00078 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold V_ATPase_I_N PF18670.1 EMR71393.1 - 0.13 12.7 0.0 0.85 10.1 0.0 2.1 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain adh_short PF00106.25 EMR71394.1 - 3.1e-13 49.6 0.0 1.4e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71394.1 - 9.7e-11 41.7 0.1 1.5e-08 34.5 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PAN_4 PF14295.6 EMR71395.1 - 0.026 14.4 0.3 0.067 13.1 0.3 1.7 1 0 0 1 1 1 0 PAN domain DUF3506 PF12014.8 EMR71397.1 - 2.8e-57 192.6 0.0 4.5e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 EMR71397.1 - 4e-07 29.8 1.0 4e-07 29.8 1.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EMR71397.1 - 0.0008 19.2 0.1 0.0019 18.0 0.1 1.7 1 1 0 1 1 1 1 F-box domain DUF1581 PF07619.11 EMR71397.1 - 0.055 13.6 0.0 20 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) F-box_4 PF15966.5 EMR71397.1 - 0.062 13.2 0.2 0.28 11.1 0.1 2.0 1 1 1 2 2 2 0 F-box Pex14_N PF04695.13 EMR71398.1 - 0.06 14.0 32.7 0.25 12.0 0.2 5.0 5 0 0 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 EMR71398.1 - 3 7.4 28.7 0.35 10.4 13.8 3.3 3 0 0 3 3 3 0 Spt20 family Glyco_hydro_18 PF00704.28 EMR71400.1 - 5.4e-20 72.3 0.4 1.6e-19 70.8 0.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.7 EMR71401.1 - 3.8e-19 69.0 0.0 1e-08 35.7 0.0 4.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR71401.1 - 1.2e-16 60.9 1.2 0.00031 21.2 0.0 6.9 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR71401.1 - 3.2e-15 54.7 0.4 3.8e-05 23.7 0.0 6.8 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 EMR71401.1 - 3.3e-14 52.6 0.5 0.00075 19.8 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EMR71401.1 - 4.2e-09 36.5 1.8 1.1 9.7 0.0 6.0 5 1 1 6 6 6 3 Ankyrin repeats (many copies) F-box PF00646.33 EMR71401.1 - 0.002 18.0 0.0 0.0058 16.5 0.0 1.7 2 0 0 2 2 2 1 F-box domain TFIIA PF03153.13 EMR71401.1 - 0.0096 16.0 17.1 0.012 15.6 17.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 EMR71401.1 - 0.38 9.5 7.9 0.44 9.3 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 EMR71401.1 - 1.3 8.4 27.2 0.78 9.1 25.5 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 EMR71401.1 - 8.2 6.9 6.2 12 6.3 6.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 GST_C_2 PF13410.6 EMR71402.1 - 0.00079 19.4 1.5 0.0012 18.8 1.4 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR71402.1 - 0.046 13.9 0.0 0.098 12.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M14 PF00246.24 EMR71403.1 - 4.8e-41 141.5 0.2 6.1e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase NAD_binding_1 PF00175.21 EMR71405.1 - 2.9e-10 40.8 0.0 5.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EMR71405.1 - 6.7e-09 36.3 0.1 5.2e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 EMR71405.1 - 2.4e-05 24.6 0.0 7.3e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EMR71405.1 - 0.013 15.6 0.4 0.62 10.2 0.1 3.2 3 1 0 4 4 4 0 Ferric reductase NAD binding domain Protoglobin PF11563.8 EMR71405.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Protoglobin Herpes_capsid PF06112.11 EMR71405.1 - 4.4 7.3 9.3 7.5 6.6 9.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cupin_2 PF07883.11 EMR71406.1 - 7.7e-09 35.2 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain GPI PF06560.11 EMR71406.1 - 0.0032 16.8 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_3 PF05899.12 EMR71406.1 - 0.0034 17.0 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 EMR71406.1 - 0.095 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_1 PF00190.22 EMR71406.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Ammonium_transp PF00909.21 EMR71407.1 - 1.6e-67 227.9 19.8 2.1e-67 227.5 19.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Peptidase_A24 PF01478.18 EMR71407.1 - 0.012 16.0 1.9 0.012 16.0 1.9 3.4 2 1 0 2 2 2 0 Type IV leader peptidase family MFS_1 PF07690.16 EMR71408.1 - 1.1e-45 156.2 32.5 1.1e-45 156.2 32.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR71408.1 - 3.4e-11 42.7 5.3 3.4e-11 42.7 5.3 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Mem_trans PF03547.18 EMR71408.1 - 0.18 10.1 6.7 16 3.7 0.0 3.0 3 0 0 3 3 3 0 Membrane transport protein DUF1769 PF08588.10 EMR71409.1 - 1.8e-27 95.3 0.7 3.5e-27 94.4 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) NESP55 PF06390.12 EMR71409.1 - 0.1 12.2 6.8 0.16 11.5 6.8 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) TFIIE-A_C PF11521.8 EMR71409.1 - 0.35 11.2 5.9 0.9 9.9 5.9 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Myc_N PF01056.18 EMR71409.1 - 0.38 10.6 6.7 0.57 10.0 6.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF5521 PF17659.1 EMR71409.1 - 1.3 6.7 2.0 1.8 6.3 2.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Pox_Ag35 PF03286.14 EMR71409.1 - 2.3 8.0 7.0 4.4 7.1 7.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleo_P87 PF07267.11 EMR71409.1 - 2.4 6.9 4.7 3.2 6.5 4.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_phi PF04931.13 EMR71409.1 - 8.1 4.4 5.0 14 3.6 5.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi CTP_transf_like PF01467.26 EMR71410.1 - 4.2e-05 23.8 0.1 0.00018 21.7 0.0 2.1 2 1 0 2 2 2 1 Cytidylyltransferase-like Get5_C PF18514.1 EMR71411.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Get5 C-terminal domain PK PF00224.21 EMR71412.1 - 9e-170 564.1 4.2 1.4e-169 563.5 4.2 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EMR71412.1 - 2.4e-35 121.3 0.0 5.9e-35 120.0 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EMR71412.1 - 0.00058 19.1 0.3 0.0032 16.6 0.2 2.1 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EMR71412.1 - 0.059 12.4 0.0 0.92 8.4 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Ank_4 PF13637.6 EMR71413.1 - 9.8e-16 57.9 0.0 0.0059 17.2 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EMR71413.1 - 1.5e-14 53.7 0.0 0.062 13.8 0.0 6.3 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EMR71413.1 - 8.1e-12 44.2 0.2 0.55 11.0 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_2 PF12796.7 EMR71413.1 - 4.1e-11 43.3 0.0 3.2e-05 24.4 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR71413.1 - 2e-06 27.9 0.7 0.2 12.0 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Apolipoprotein PF01442.18 EMR71414.1 - 0.044 13.6 5.0 0.076 12.9 5.0 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3416 PF11896.8 EMR71414.1 - 0.059 13.7 0.5 0.064 13.5 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Caskin-tail PF16632.5 EMR71414.1 - 0.16 12.4 2.6 0.27 11.7 2.6 1.5 1 0 0 1 1 1 0 C-terminal region of Caskin adh_short_C2 PF13561.6 EMR71415.1 - 3.5e-52 177.3 0.6 4.3e-52 177.0 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR71415.1 - 2.8e-36 124.8 0.5 4e-36 124.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR71415.1 - 4.5e-10 39.7 0.4 6.6e-10 39.2 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR71415.1 - 1.4e-06 27.9 0.0 3.4e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR71415.1 - 2.3e-05 24.0 0.0 0.00065 19.2 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EMR71415.1 - 0.06 13.4 0.8 0.085 12.9 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 EMR71415.1 - 0.075 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1748 PF08520.10 EMR71416.1 - 1.1e-34 118.2 0.1 1.3e-34 117.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.32 EMR71417.1 - 2.7e-13 50.1 4.7 5.8e-05 23.8 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Beta-lactamase PF00144.24 EMR71418.1 - 2.3e-48 165.1 2.7 3.2e-48 164.7 2.7 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EMR71418.1 - 1.1e-05 25.8 0.0 4e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) Cwf_Cwc_15 PF04889.12 EMR71418.1 - 0.25 11.1 0.9 0.36 10.5 0.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SARAF PF06682.12 EMR71419.1 - 0.0081 15.8 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 EMR71419.1 - 0.023 15.7 0.3 0.088 13.8 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2157 PF09925.9 EMR71420.1 - 0.037 13.8 0.1 0.078 12.8 0.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF2530 PF10745.9 EMR71420.1 - 5.5 7.3 7.0 0.9 9.8 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) zf-rbx1 PF12678.7 EMR71421.1 - 5.6e-05 23.3 2.8 9.1e-05 22.7 2.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EMR71421.1 - 6.9e-05 23.1 5.3 0.00051 20.3 5.3 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EMR71421.1 - 8e-05 22.4 0.8 0.00019 21.2 0.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMR71421.1 - 0.00022 21.0 5.8 0.0027 17.5 5.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR71421.1 - 0.00042 20.3 2.0 0.0014 18.6 2.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMR71421.1 - 0.0011 18.9 0.5 0.0016 18.4 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EMR71421.1 - 0.0028 17.6 4.7 0.0063 16.5 4.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Pellino PF04710.14 EMR71421.1 - 0.0063 15.2 0.6 0.0087 14.8 0.6 1.1 1 0 0 1 1 1 1 Pellino zf-C3HC4_2 PF13923.6 EMR71421.1 - 0.025 14.4 0.9 0.025 14.4 0.9 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMR71421.1 - 0.11 12.3 2.2 0.34 10.8 2.2 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF3673 PF12425.8 EMR71421.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) FANCL_C PF11793.8 EMR71421.1 - 0.73 10.1 3.6 2.6 8.3 3.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EMR71421.1 - 1.9 8.3 6.6 6.8 6.5 0.1 2.7 3 0 0 3 3 3 0 RING-like zinc finger adh_short_C2 PF13561.6 EMR71422.1 - 4.6e-29 101.6 0.0 5.2e-27 94.9 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR71422.1 - 3.3e-23 82.1 0.7 1.2e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR71422.1 - 6e-05 23.0 0.0 0.00024 21.1 0.0 2.1 1 1 0 1 1 1 1 KR domain DUF4796 PF16044.5 EMR71422.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) 7tm_1 PF00001.21 EMR71423.1 - 0.0091 15.3 0.6 0.013 14.8 0.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_hydro_61 PF03443.14 EMR71424.1 - 1.8e-51 175.0 0.0 3.7e-51 174.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EMR71424.1 - 3.8e-12 45.9 11.8 1e-11 44.5 11.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Kinesin PF00225.23 EMR71426.1 - 1.5e-56 191.7 0.0 1.3e-31 109.8 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EMR71426.1 - 4.9e-09 36.3 0.0 9.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding SRP40_C PF05022.12 EMR71427.1 - 1e-24 87.1 0.4 1e-24 87.1 0.4 2.6 2 0 0 2 2 2 1 SRP40, C-terminal domain adh_short PF00106.25 EMR71428.1 - 6.1e-20 71.5 0.1 3.7e-17 62.4 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71428.1 - 1e-08 35.1 0.1 1.1e-07 31.7 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71428.1 - 0.00018 21.4 0.6 0.00026 20.9 0.6 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR71430.1 - 1.8e-09 37.8 0.0 2.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR71430.1 - 4e-09 36.3 0.0 1.1e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 EMR71430.1 - 2.1e-07 30.6 0.0 3.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 HIM1 NmrA PF05368.13 EMR71430.1 - 0.00014 21.5 0.0 0.00064 19.3 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EMR71430.1 - 0.012 14.8 0.0 0.15 11.2 0.0 2.3 1 1 2 3 3 3 0 Male sterility protein 3Beta_HSD PF01073.19 EMR71430.1 - 0.019 14.0 0.0 0.23 10.4 0.0 2.2 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2OG-FeII_Oxy_2 PF13532.6 EMR71432.1 - 1.8e-31 109.9 0.0 2.6e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PEX11 PF05648.14 EMR71433.1 - 2.4e-22 79.5 3.5 6.7e-10 38.8 1.9 3.8 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Cyclin_N PF00134.23 EMR71434.1 - 1.4e-14 53.9 0.0 2.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EMR71434.1 - 2.3e-07 31.3 0.0 4.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin NAD_binding_8 PF13450.6 EMR71435.1 - 1.9e-13 50.4 0.1 5.4e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMR71435.1 - 1.8e-06 27.6 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EMR71435.1 - 2.1e-06 27.3 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EMR71435.1 - 2.6e-05 23.5 0.9 3.6e-05 23.0 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMR71435.1 - 0.00012 21.8 0.6 0.00025 20.8 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR71435.1 - 0.00016 20.5 0.2 0.00025 19.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EMR71435.1 - 0.00087 18.6 0.2 0.0015 17.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EMR71435.1 - 0.0019 18.7 0.2 0.008 16.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR71435.1 - 0.0024 17.1 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR71435.1 - 0.01 15.1 0.3 0.016 14.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EMR71435.1 - 0.031 13.6 0.1 0.051 12.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMR71435.1 - 0.097 12.9 0.1 0.31 11.3 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain PSD2 PF07624.11 EMR71435.1 - 0.14 12.0 0.2 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Lycopene_cycl PF05834.12 EMR71435.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DHBP_synthase PF00926.19 EMR71436.1 - 1.3e-80 269.4 0.0 1.5e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.6 EMR71437.1 - 2.1e-19 69.9 0.0 3.2e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR71437.1 - 9.7e-17 61.4 0.0 1.6e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR71437.1 - 3.4e-13 50.1 0.0 6.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR71437.1 - 2.4e-12 47.5 0.0 4.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR71437.1 - 1.8e-11 44.0 0.0 2.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMR71437.1 - 0.00025 20.6 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EMR71437.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EMR71437.1 - 0.0034 16.7 0.0 0.0065 15.8 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EMR71437.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 EMR71437.1 - 0.047 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 EMR71437.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3439 PF11921.8 EMR71437.1 - 10 6.1 8.4 2.7 8.0 4.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Hexapep PF00132.24 EMR71438.1 - 3.5e-08 32.8 10.2 6.1e-05 22.6 0.7 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMR71438.1 - 0.00071 19.3 3.5 0.49 10.2 0.2 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase HET PF06985.11 EMR71440.1 - 3.9e-27 95.4 0.0 7.9e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1796 PF08795.10 EMR71440.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Complex1_51K PF01512.17 EMR71441.1 - 1.5e-47 161.2 0.0 2.5e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EMR71441.1 - 1.4e-28 98.8 1.5 1.8e-28 98.4 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EMR71441.1 - 4.4e-09 36.1 0.0 1.5e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 SLBB domain Rad4 PF03835.15 EMR71442.1 - 2.2e-11 43.7 0.5 3.3e-11 43.0 0.5 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EMR71442.1 - 1.1e-09 38.7 0.8 2.6e-09 37.5 0.8 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily PAW PF04721.17 EMR71442.1 - 0.099 12.4 0.3 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Pkinase PF00069.25 EMR71443.1 - 6.8e-70 235.4 0.0 8.6e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR71443.1 - 7.1e-31 107.4 0.0 8.9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMR71443.1 - 0.0014 17.6 0.0 0.018 14.0 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EMR71443.1 - 0.0025 17.8 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EMR71443.1 - 0.0042 16.4 0.0 0.0086 15.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EMR71443.1 - 0.02 13.9 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EMR71443.1 - 0.063 12.6 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.25 EMR71444.1 - 5.5e-34 117.3 0.1 7e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71444.1 - 9.1e-25 87.6 0.1 1.2e-24 87.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71444.1 - 4.5e-06 26.7 0.5 1.2e-05 25.3 0.5 1.7 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EMR71444.1 - 0.00015 20.9 0.1 0.00026 20.2 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMR71444.1 - 0.0051 16.7 0.2 0.0069 16.3 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding p450 PF00067.22 EMR71445.1 - 5.8e-45 153.9 0.0 1e-38 133.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 HET PF06985.11 EMR71446.1 - 4.1e-13 49.9 0.0 8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) E1_dh PF00676.20 EMR71447.1 - 0.058 12.3 0.1 0.071 12.1 0.1 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component DNA_ligase_OB_2 PF14743.6 EMR71447.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA ligase OB-like domain Pox_A12 PF04651.13 EMR71448.1 - 0.18 11.9 0.6 0.35 10.9 0.6 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein ASCH PF04266.14 EMR71449.1 - 0.0036 17.9 0.0 0.0069 17.0 0.0 1.5 1 0 0 1 1 1 1 ASCH domain PAS_9 PF13426.7 EMR71450.1 - 1.9e-11 44.2 0.0 2.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EMR71450.1 - 0.00063 20.0 0.0 0.0037 17.5 0.0 2.0 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMR71450.1 - 0.0028 17.9 0.0 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EMR71450.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.6 1 1 0 1 1 1 0 PAS fold NUDIX PF00293.28 EMR71451.1 - 4.1e-05 23.6 0.0 5.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_6 PF12697.7 EMR71452.1 - 1.5e-12 48.7 10.3 2.9e-12 47.7 10.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR71452.1 - 5.9e-05 22.4 0.0 9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR71452.1 - 0.0029 17.3 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 EMR71452.1 - 0.097 11.4 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Ndr family HECT PF00632.25 EMR71453.1 - 4.2e-52 177.6 0.0 7.3e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EMR71453.1 - 0.00065 19.6 2.1 3.4 7.9 0.1 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat SDA1 PF05285.12 EMR71453.1 - 0.0021 17.6 23.2 0.0021 17.6 23.2 3.0 3 0 0 3 3 3 1 SDA1 BUD22 PF09073.10 EMR71453.1 - 0.0035 16.7 16.1 0.0035 16.7 16.1 3.1 3 0 0 3 3 3 1 BUD22 HEAT PF02985.22 EMR71453.1 - 0.0064 16.7 1.1 1.2 9.6 0.0 4.0 4 0 0 4 4 3 1 HEAT repeat CLASP_N PF12348.8 EMR71453.1 - 0.024 14.2 0.1 0.19 11.3 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal DUF913 PF06025.12 EMR71453.1 - 0.097 11.6 4.5 0.44 9.5 3.7 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) LAP1C PF05609.12 EMR71453.1 - 0.41 9.7 11.3 0.73 8.9 11.3 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Telomere_reg-2 PF10193.9 EMR71453.1 - 0.95 9.9 4.2 28 5.2 0.1 3.7 3 0 0 3 3 3 0 Telomere length regulation protein PI3K_1B_p101 PF10486.9 EMR71453.1 - 1.5 6.5 7.9 2.2 6.0 7.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 EMR71453.1 - 2.1 7.0 9.1 4.1 6.1 9.1 1.4 1 0 0 1 1 1 0 Presenilin DUF1387 PF07139.11 EMR71454.1 - 4.4 6.9 10.9 2.5 7.7 7.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Complex1_30kDa PF00329.19 EMR71455.1 - 6e-45 152.8 0.0 8.9e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Rot1 PF10681.9 EMR71456.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Pkinase PF00069.25 EMR71457.1 - 0.0039 16.6 0.0 0.12 11.8 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain zf-RING_4 PF14570.6 EMR71458.1 - 8.1e-21 73.6 11.5 1.4e-20 72.8 11.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EMR71458.1 - 6.7e-09 35.4 0.1 2.9e-08 33.4 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 EMR71458.1 - 1.7e-08 34.2 6.6 3.6e-08 33.1 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EMR71458.1 - 1.1e-05 25.0 2.9 1.3e-05 24.8 2.9 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 EMR71458.1 - 3.4e-05 24.1 9.9 3.4e-05 24.1 9.9 2.0 2 1 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EMR71458.1 - 5.6e-05 22.9 9.0 0.0012 18.7 4.2 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 EMR71458.1 - 0.0014 18.6 4.4 0.0029 17.5 4.4 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 EMR71458.1 - 0.0016 18.4 9.8 0.0041 17.1 9.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain SET_assoc PF11767.8 EMR71458.1 - 0.0026 17.4 0.2 0.0066 16.1 0.0 1.8 2 0 0 2 2 1 1 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 EMR71458.1 - 0.0087 16.0 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-UDP PF14569.6 EMR71458.1 - 0.012 15.7 3.2 0.035 14.2 3.2 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.21 EMR71458.1 - 0.013 15.6 6.3 0.032 14.4 6.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 EMR71458.1 - 0.013 15.7 4.0 0.013 15.7 4.0 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger DUF576 PF04507.12 EMR71458.1 - 0.042 13.3 2.0 0.058 12.8 2.0 1.2 1 0 0 1 1 1 0 Csa1 family zf-C3HC4 PF00097.25 EMR71458.1 - 0.054 13.4 9.9 0.14 12.0 9.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMR71458.1 - 0.15 12.0 9.8 0.39 10.6 9.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_3 PF08777.11 EMR71458.1 - 0.18 11.8 4.5 0.29 11.2 1.9 2.3 2 1 0 2 2 2 0 RNA binding motif Rad50_zn_hook PF04423.14 EMR71458.1 - 0.73 9.7 5.6 5.4 6.9 0.1 2.8 3 0 0 3 3 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.6 EMR71458.1 - 3.8 7.6 13.7 0.27 11.3 5.5 2.6 3 0 0 3 3 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EMR71458.1 - 5.5 7.2 11.8 93 3.3 12.1 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING CTU2 PF10288.9 EMR71458.1 - 5.6 7.3 8.2 7.1 6.9 6.7 2.1 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Glyco_hydro_32C PF08244.12 EMR71459.1 - 1.6e-21 77.0 0.2 2.8e-21 76.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 EMR71459.1 - 2.4e-16 60.2 0.0 4.3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain CDH-cyt PF16010.5 EMR71460.1 - 1.3e-53 181.4 0.0 2e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EMR71460.1 - 9.6e-26 90.8 0.0 1.9e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR71460.1 - 1.4e-17 64.5 0.0 2.7e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR71460.1 - 1.1e-05 24.8 2.8 7.5e-05 22.0 1.0 2.6 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 EMR71460.1 - 0.00055 18.8 2.8 0.0046 15.7 1.4 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 EMR71460.1 - 0.0007 18.9 0.5 0.0096 15.2 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR71460.1 - 0.00099 18.6 1.5 0.0019 17.6 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR71460.1 - 0.0011 19.2 0.2 0.0029 17.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR71460.1 - 0.016 14.8 2.8 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EMR71460.1 - 0.061 12.5 1.2 0.16 11.2 0.5 1.9 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EMR71460.1 - 0.068 12.2 0.2 0.068 12.2 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMR71460.1 - 0.1 11.8 0.3 0.77 9.0 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 EMR71461.1 - 1e-114 383.9 27.3 1.2e-114 383.7 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR71461.1 - 4.8e-25 88.2 33.2 3.4e-23 82.2 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMR71461.1 - 7.1e-05 21.5 32.2 0.004 15.8 7.5 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Herpes_LAMP2 PF06126.11 EMR71461.1 - 0.058 12.0 4.5 0.11 11.0 4.5 1.5 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 DUF5316 PF17247.2 EMR71461.1 - 0.1 12.6 0.1 0.1 12.6 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5316) DUF4396 PF14342.6 EMR71462.1 - 8.1 6.8 12.8 0.18 12.1 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4396) FAD_binding_4 PF01565.23 EMR71463.1 - 6.5e-11 42.1 1.2 1.2e-07 31.6 0.1 3.0 1 1 2 3 3 3 2 FAD binding domain BBE PF08031.12 EMR71463.1 - 0.00011 22.2 0.7 0.00024 21.1 0.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like NmrA PF05368.13 EMR71464.1 - 3.7e-22 79.0 0.0 4.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR71464.1 - 1.4e-18 67.5 0.0 2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMR71464.1 - 5.9e-06 26.6 0.1 1.6e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EMR71464.1 - 6e-05 22.6 0.1 0.00019 20.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR71464.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 EMR71464.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EMR71464.1 - 0.1 13.2 0.1 0.33 11.6 0.1 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 EMR71465.1 - 5.1e-30 104.6 31.0 7.3e-30 104.1 31.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR71465.1 - 4.8e-05 22.8 6.8 4.8e-05 22.8 6.8 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB C2 PF00168.30 EMR71466.1 - 1.2e-80 266.5 0.0 6.2e-22 77.8 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EMR71466.1 - 0.00064 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain FKBP_C PF00254.28 EMR71466.1 - 0.063 13.6 0.1 0.6 10.5 0.0 2.6 3 0 0 3 3 3 0 FKBP-type peptidyl-prolyl cis-trans isomerase Fructosamin_kin PF03881.14 EMR71467.1 - 8.7e-44 149.8 0.0 1.1e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Inv-AAD PF18785.1 EMR71467.1 - 4.4e-42 143.0 0.0 6.5e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EMR71467.1 - 8.4e-12 44.9 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APH PF01636.23 EMR71467.1 - 3.9e-06 27.0 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family APOBEC_N PF08210.11 EMR71467.1 - 0.0096 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.6 EMR71467.1 - 0.089 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase p450 PF00067.22 EMR71468.1 - 3.8e-28 98.4 0.0 4.4e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polyketide_cyc PF03364.20 EMR71468.1 - 0.11 12.7 0.5 0.4 10.9 0.4 2.2 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Fungal_trans PF04082.18 EMR71469.1 - 1.6e-12 47.0 0.6 3.7e-12 45.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain AvrPphF-ORF-2 PF09143.10 EMR71469.1 - 0.025 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 AvrPphF-ORF-2 Glyco_transf_56 PF07429.11 EMR71469.1 - 0.056 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 COesterase PF00135.28 EMR71470.1 - 2.4e-53 181.8 0.0 2.8e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR71470.1 - 0.0044 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold FTZ PF03867.14 EMR71472.1 - 0.1 12.1 3.5 0.19 11.2 3.5 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Spore_coat_CotO PF14153.6 EMR71472.1 - 1.4 8.8 6.2 2.3 8.1 6.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Glyco_hydro_3 PF00933.21 EMR71473.1 - 7.4e-53 180.0 0.0 9.5e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EMR71473.1 - 1.3e-38 133.0 0.0 2.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EMR71473.1 - 9.9e-15 54.4 0.2 1.8e-14 53.6 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PS-DH PF14765.6 EMR71474.1 - 2.4e-62 210.8 0.0 4e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EMR71474.1 - 1.3e-53 182.6 0.0 2.3e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EMR71474.1 - 1.5e-39 136.1 0.0 1.5e-25 90.2 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR71474.1 - 4.4e-33 113.8 0.0 1.1e-32 112.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EMR71474.1 - 1.7e-26 93.2 0.0 4.4e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EMR71474.1 - 5.8e-14 52.2 0.1 2.2e-13 50.3 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EMR71474.1 - 3.8e-12 46.8 0.0 3.7e-11 43.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EMR71474.1 - 8.3e-10 39.8 0.0 3.4e-09 37.9 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EMR71474.1 - 4.7e-09 36.3 0.0 1.4e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR71474.1 - 2.1e-07 31.2 0.2 5.6e-07 29.8 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EMR71474.1 - 0.00013 21.8 0.0 0.001 18.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 EMR71474.1 - 0.00024 20.9 0.0 0.0006 19.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EMR71474.1 - 0.00045 20.8 0.0 0.0027 18.3 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EMR71474.1 - 0.00055 20.4 0.0 1.4 9.4 0.0 2.7 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension Ubie_methyltran PF01209.18 EMR71474.1 - 0.0047 16.3 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family SAT PF16073.5 EMR71474.1 - 0.0087 15.8 0.3 0.57 9.9 0.0 2.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF4614 PF15391.6 EMR71475.1 - 0.013 15.5 12.4 0.019 15.0 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DDHD PF02862.17 EMR71475.1 - 0.09 12.9 3.8 0.096 12.8 3.8 1.1 1 0 0 1 1 1 0 DDHD domain AAR2 PF05282.11 EMR71475.1 - 0.19 11.1 4.9 0.21 11.0 4.9 1.1 1 0 0 1 1 1 0 AAR2 protein MID_MedPIWI PF18296.1 EMR71475.1 - 0.2 11.4 7.7 0.24 11.1 7.7 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Plasmodium_Vir PF05795.11 EMR71475.1 - 4.5 6.6 5.7 5.4 6.3 5.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CASP_C PF08172.12 EMR71475.1 - 6.3 6.1 9.1 8 5.7 9.1 1.2 1 0 0 1 1 1 0 CASP C terminal ketoacyl-synt PF00109.26 EMR71476.1 - 1.8e-68 230.8 0.2 4.6e-68 229.5 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EMR71476.1 - 6.2e-60 202.2 1.7 8.9e-60 201.7 0.4 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EMR71476.1 - 1.7e-48 165.8 0.9 2.8e-48 165.1 0.9 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EMR71476.1 - 3.7e-46 157.7 0.1 6.9e-46 156.8 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EMR71476.1 - 4.3e-37 126.7 0.2 2e-36 124.6 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EMR71476.1 - 3.5e-16 60.5 0.1 1.7e-14 55.0 0.0 3.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR71476.1 - 1.5e-14 54.1 0.0 5.6e-14 52.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMR71476.1 - 4.8e-14 52.3 2.0 6.5e-13 48.6 0.4 2.6 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EMR71476.1 - 4.6e-13 49.6 0.0 1.8e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EMR71476.1 - 5.2e-08 33.5 0.0 1.3e-07 32.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR71476.1 - 5.5e-08 33.4 0.0 2.3e-07 31.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR71476.1 - 3.2e-06 27.1 0.0 7.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 EMR71476.1 - 7.1e-06 25.9 1.3 3.1e-05 23.8 1.3 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 EMR71476.1 - 1.9e-05 24.9 0.0 6.4e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EMR71476.1 - 0.00011 21.7 0.8 0.00025 20.5 0.2 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.12 EMR71476.1 - 0.00013 21.8 0.0 0.00037 20.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 EMR71476.1 - 0.036 13.2 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EMR71476.1 - 0.098 11.6 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Terminase_3C PF17288.2 EMR71477.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Terminase RNAseH like domain MFS_1 PF07690.16 EMR71478.1 - 2.3e-24 86.0 57.9 6.5e-16 58.2 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM171 PF15471.6 EMR71478.1 - 4.5 6.2 6.3 0.31 10.0 1.1 1.7 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF1304 PF06993.12 EMR71478.1 - 4.5 7.3 15.4 0.24 11.4 5.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) Sulfatase PF00884.23 EMR71479.1 - 2.6e-62 211.0 0.1 3.5e-62 210.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EMR71479.1 - 1.8e-21 76.3 6.6 1.8e-20 73.1 6.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 EMR71479.1 - 6.7e-07 29.2 0.7 6.7e-07 29.2 0.7 2.3 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EMR71479.1 - 0.0028 18.4 0.3 0.0065 17.2 0.3 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 EMR71479.1 - 0.0074 15.0 0.0 0.016 13.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Methyltransf_2 PF00891.18 EMR71480.1 - 2.4e-15 56.4 0.0 3.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EMR71480.1 - 2.7e-08 34.4 0.0 1.4e-07 32.2 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR71480.1 - 0.00022 21.9 0.0 0.00046 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR71480.1 - 0.00054 19.8 0.0 0.0019 18.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR71480.1 - 0.00065 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 EMR71480.1 - 0.0011 18.9 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR71480.1 - 0.0054 17.3 0.0 0.035 14.7 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR71480.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EMR71480.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.12 EMR71480.1 - 0.032 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_32 PF13679.6 EMR71480.1 - 0.065 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 EMR71481.1 - 5.8e-06 25.5 0.1 1.1e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_11 PF17123.5 EMR71483.1 - 0.00013 21.6 4.3 0.00013 21.6 4.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EMR71483.1 - 0.00083 19.6 5.4 0.00083 19.6 5.4 2.5 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EMR71483.1 - 0.0043 17.1 4.8 0.0043 17.1 4.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMR71483.1 - 0.18 11.7 11.9 0.17 11.7 5.6 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.17 EMR71484.1 - 2.8e-08 33.8 0.0 5.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EMR71484.1 - 0.0011 19.4 0.1 0.0022 18.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 EMR71484.1 - 0.12 12.6 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) TPR_1 PF00515.28 EMR71485.1 - 1.4e-07 31.0 8.2 0.00097 18.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR71485.1 - 5.3e-06 26.2 16.2 0.017 15.2 0.4 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMR71485.1 - 8.4e-05 23.1 11.8 21 6.3 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMR71485.1 - 0.00011 21.8 2.1 0.18 11.5 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 EMR71485.1 - 0.0022 18.1 10.3 0.19 12.1 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMR71485.1 - 0.0027 18.2 11.0 0.85 10.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR71485.1 - 0.0051 17.0 9.7 0.5 10.6 0.5 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EMR71485.1 - 0.011 15.7 7.6 0.018 15.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Trehalase PF01204.18 EMR71485.1 - 0.05 12.4 0.1 0.08 11.8 0.1 1.3 1 0 0 1 1 1 0 Trehalase TPR_12 PF13424.6 EMR71485.1 - 0.071 13.4 14.7 2.7 8.3 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMR71485.1 - 0.12 12.8 5.8 3.4 8.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMR71485.1 - 0.16 11.9 7.6 1 9.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMR71485.1 - 5.8 7.8 9.0 4.5 8.1 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Glyoxalase PF00903.25 EMR71486.1 - 0.0034 17.6 0.0 0.0042 17.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BTB PF00651.31 EMR71487.1 - 6.7e-05 23.1 0.0 0.00016 21.8 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Mito_carr PF00153.27 EMR71488.1 - 1.7e-57 191.3 0.4 9.2e-20 70.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 EMR71489.1 - 1.6e-28 99.6 0.0 2.5e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EMR71489.1 - 3.1e-08 34.0 0.1 4.1e-05 23.9 0.0 3.9 3 1 0 3 3 3 2 Calpain large subunit, domain III Methyltransf_2 PF00891.18 EMR71491.1 - 3.2e-28 98.5 0.0 4.4e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 EMR71491.1 - 0.0016 17.6 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EMR71491.1 - 0.015 16.0 0.0 0.034 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EMR71491.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain GMC_oxred_N PF00732.19 EMR71492.1 - 1.4e-25 90.3 0.0 2.3e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR71492.1 - 1.9e-23 83.6 0.2 4e-23 82.6 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR71492.1 - 8.5e-10 38.3 0.2 0.00033 19.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.18 EMR71492.1 - 7.2e-08 32.3 4.5 1.6e-07 31.2 4.5 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain NAD_binding_8 PF13450.6 EMR71492.1 - 5.3e-05 23.4 0.3 0.00015 21.9 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR71492.1 - 0.00066 19.4 0.7 0.0038 16.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR71492.1 - 0.0021 16.9 0.1 0.0034 16.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EMR71492.1 - 0.0041 16.4 0.0 0.0084 15.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR71492.1 - 0.0046 16.4 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMR71492.1 - 0.0077 15.5 0.4 0.055 12.7 1.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR71492.1 - 0.03 13.4 0.1 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EMR71492.1 - 0.037 13.3 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EMR71492.1 - 0.12 12.9 0.0 1 10.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GFA PF04828.14 EMR71493.1 - 1.2e-17 64.0 0.5 1.6e-17 63.6 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme TMEM174 PF15029.6 EMR71494.1 - 0.061 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 174 PAF-AH_p_II PF03403.13 EMR71495.1 - 3.7e-18 65.2 0.0 4e-09 35.5 0.0 2.1 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 EMR71495.1 - 1.7e-05 24.7 0.3 0.29 10.9 0.0 2.7 2 1 0 2 2 2 2 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EMR71495.1 - 7.5e-05 21.8 0.0 0.00032 19.7 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EMR71495.1 - 0.00016 21.0 0.0 0.32 10.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR71495.1 - 0.00023 21.9 0.1 0.00031 21.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR71495.1 - 0.052 13.2 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EMR71495.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CTP_transf_3 PF02348.19 EMR71495.1 - 0.15 12.0 0.2 0.21 11.5 0.2 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Peptidase_S9 PF00326.21 EMR71495.1 - 0.15 11.5 0.1 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family TBP PF00352.21 EMR71496.1 - 2.7e-64 213.1 0.1 1.4e-32 111.4 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EMR71496.1 - 0.00046 20.2 0.0 0.58 10.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Aminotran_5 PF00266.19 EMR71497.1 - 1.4e-16 60.5 0.0 1.9e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V U-box PF04564.15 EMR71499.1 - 1.1e-20 73.5 0.3 3e-20 72.2 0.1 1.9 2 1 0 2 2 2 1 U-box domain TPR_1 PF00515.28 EMR71499.1 - 1.5e-07 30.9 1.1 0.0037 17.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR71499.1 - 8.6e-07 28.6 3.7 0.41 10.9 0.3 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMR71499.1 - 0.0077 16.4 3.4 0.17 12.2 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR71499.1 - 0.0089 16.7 0.0 1.9 9.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 EMR71499.1 - 0.013 16.3 12.2 0.036 14.8 12.2 1.8 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain TPR_17 PF13431.6 EMR71499.1 - 0.022 15.1 1.1 3.1 8.4 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMR71499.1 - 0.036 13.8 0.4 0.22 11.3 0.1 2.3 2 0 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 EMR71499.1 - 0.044 14.0 3.4 1.1 9.5 1.2 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-NOSIP PF15906.5 EMR71499.1 - 0.05 13.7 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Aminopep PF10023.9 EMR71499.1 - 0.06 12.7 1.1 0.12 11.7 1.1 1.4 1 0 0 1 1 1 0 Putative aminopeptidase Fis1_TPR_C PF14853.6 EMR71499.1 - 0.11 12.5 0.5 1.9 8.6 0.0 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EMR71499.1 - 0.17 12.2 4.3 0.19 12.1 0.9 2.6 3 1 0 3 3 3 0 Tetratricopeptide repeat CemA PF03040.14 EMR71499.1 - 0.22 11.5 0.4 0.33 10.8 0.4 1.3 1 0 0 1 1 1 0 CemA family Sec16_C PF12931.7 EMR71501.1 - 7.6e-08 32.4 0.0 6.4e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 EMR71501.1 - 1.5e-06 28.8 5.5 0.074 14.0 0.1 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat PALB2_WD40 PF16756.5 EMR71501.1 - 0.045 12.7 0.1 0.44 9.4 0.0 2.4 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain RRM_1 PF00076.22 EMR71502.1 - 2.1e-18 65.9 0.0 3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR71502.1 - 0.00013 22.0 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EMR71502.1 - 0.045 13.8 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EMR71502.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EMR71502.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.7 1 1 0 1 1 1 0 RNA binding motif DUF4188 PF13826.6 EMR71503.1 - 1.5e-15 57.6 0.0 1.9e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) DUF3291 PF11695.8 EMR71503.1 - 0.0053 16.4 0.0 0.0073 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) Dehydratase_hem PF13816.6 EMR71503.1 - 0.022 14.2 0.0 0.049 13.0 0.0 1.6 2 1 0 2 2 2 0 Haem-containing dehydratase NAD_binding_4 PF07993.12 EMR71504.1 - 5.4e-17 61.8 0.0 2.2e-16 59.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EMR71504.1 - 8.9e-08 32.4 0.1 3.6e-07 30.4 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EMR71504.1 - 3.4e-07 30.0 0.0 7.5e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMR71504.1 - 0.073 12.6 0.1 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family KR PF08659.10 EMR71504.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain Myb_DNA-binding PF00249.31 EMR71505.1 - 3.9e-37 126.2 16.5 1.8e-14 53.7 0.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR71505.1 - 8.2e-33 112.5 16.6 3.5e-14 52.8 0.3 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EMR71505.1 - 1.4e-08 34.5 2.2 0.00047 20.0 0.1 3.3 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 EMR71505.1 - 0.00022 21.2 0.5 1.5 8.9 0.1 3.1 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 EMR71505.1 - 0.0029 17.8 4.4 0.09 13.0 0.3 3.0 2 1 0 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EMR71505.1 - 0.017 15.2 9.0 2.9e+02 1.6 9.0 3.4 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Atg29_N PF18388.1 EMR71505.1 - 0.039 13.8 1.5 0.039 13.8 1.5 2.5 4 0 0 4 4 4 0 Atg29 N-terminal domain Myb_DNA-bind_5 PF13873.6 EMR71505.1 - 1.5 9.0 11.9 49 4.1 0.1 4.7 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain Translin PF01997.16 EMR71506.1 - 9.1e-48 163.0 0.0 1.1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Translin family EcsC PF12787.7 EMR71506.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 EcsC protein family DUF3450 PF11932.8 EMR71506.1 - 0.06 12.7 0.6 0.091 12.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) KIX PF02172.16 EMR71506.1 - 0.25 11.6 2.5 0.44 10.8 0.9 2.2 2 1 0 2 2 2 0 KIX domain SelP_N PF04592.14 EMR71507.1 - 2 7.8 7.1 2.7 7.3 7.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Mannosyl_trans PF05007.13 EMR71508.1 - 3.5e-75 253.2 1.7 4.5e-62 210.2 1.9 2.1 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EMR71508.1 - 6.6e-15 55.0 4.2 7.4e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Serglycin PF04360.12 EMR71508.1 - 0.059 13.3 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Serglycin NMT1 PF09084.11 EMR71509.1 - 3.8e-78 262.4 0.0 4.7e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EMR71509.1 - 2.2e-05 24.3 0.0 0.28 10.8 0.0 3.4 3 1 0 3 3 3 2 NMT1-like family Phosphonate-bd PF12974.7 EMR71509.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein HET PF06985.11 EMR71510.1 - 2.2e-15 57.3 0.1 3.6e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M28 PF04389.17 EMR71511.1 - 2.1e-32 112.4 0.4 2.9e-32 112.0 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EMR71511.1 - 0.00013 21.7 1.7 0.00028 20.7 0.9 2.0 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 ING PF12998.7 EMR71513.1 - 3.1e-20 72.7 2.2 4.7e-20 72.1 2.2 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EMR71513.1 - 2.4e-05 24.1 8.7 4.9e-05 23.1 8.7 1.5 1 0 0 1 1 1 1 PHD-finger PPP4R2 PF09184.11 EMR71513.1 - 1.7 8.1 7.0 2.6 7.6 7.0 1.3 1 0 0 1 1 1 0 PPP4R2 SelP_N PF04592.14 EMR71513.1 - 2.6 7.4 16.5 4.3 6.7 16.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UDPGP PF01704.18 EMR71514.1 - 8.1e-191 634.1 0.0 9.5e-191 633.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Hist_deacetyl PF00850.19 EMR71515.1 - 1.7e-81 274.1 0.0 2.5e-81 273.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF3605 PF12239.8 EMR71516.1 - 4.4e-58 196.0 0.5 5.4e-58 195.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.18 EMR71517.1 - 1.2e-05 25.8 0.0 1.5e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Dihydroneopterin aldolase Peptidase_M28 PF04389.17 EMR71518.1 - 7.6e-38 130.2 0.0 1.1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMR71518.1 - 1.6e-12 47.3 3.6 3.2e-11 43.1 0.1 3.1 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.28 EMR71518.1 - 0.0048 16.6 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Diphthami_syn_2 PF01902.17 EMR71519.1 - 6.4e-16 58.5 0.0 6.5e-05 22.5 0.0 4.1 4 0 0 4 4 4 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EMR71519.1 - 4.3e-11 42.9 0.1 2.4e-06 27.6 0.0 3.9 4 0 0 4 4 4 2 Endoribonuclease L-PSP zf-C2H2 PF00096.26 EMR71520.1 - 5.8e-12 45.4 14.4 9e-07 29.0 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMR71520.1 - 1.1e-08 35.1 16.9 8.7e-08 32.3 4.4 3.6 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMR71520.1 - 2e-07 31.3 12.3 0.00024 21.7 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EMR71520.1 - 0.00012 22.3 7.4 0.0088 16.4 0.8 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMR71520.1 - 0.0011 19.2 5.4 0.066 13.5 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 EMR71520.1 - 0.0073 16.3 2.3 0.0073 16.3 2.3 2.2 1 1 1 2 2 2 1 BED zinc finger zf_C2H2_ZHX PF18387.1 EMR71520.1 - 0.013 15.2 5.4 0.68 9.6 0.1 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 EMR71520.1 - 0.02 14.9 1.4 0.02 14.9 1.4 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EMR71520.1 - 0.035 13.9 0.2 0.035 13.9 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-AN1 PF01428.16 EMR71520.1 - 0.06 13.5 2.5 2.6 8.3 0.3 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger zf-Sec23_Sec24 PF04810.15 EMR71520.1 - 0.11 12.6 1.0 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger TFIIS_C PF01096.18 EMR71520.1 - 0.12 12.3 1.7 15 5.5 0.1 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_3rep PF18868.1 EMR71520.1 - 0.13 12.9 9.8 8.6 7.1 0.1 3.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 EMR71520.1 - 0.19 11.9 5.4 2.4 8.4 5.6 2.4 1 1 1 2 2 2 0 Zinc ribbon domain Actin_micro PF17003.5 EMR71520.1 - 0.76 8.9 3.0 7.2 5.7 3.0 2.2 1 1 0 1 1 1 0 Putative actin-like family LIM PF00412.22 EMR71520.1 - 0.98 9.7 5.9 1.5 9.1 4.6 2.1 2 1 0 2 2 2 0 LIM domain Elf1 PF05129.13 EMR71520.1 - 1.3 9.1 6.8 6.4 6.9 1.6 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2HE PF16278.5 EMR71520.1 - 2.6 8.5 9.8 1.8e+02 2.6 9.8 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 EMR71520.1 - 6.6 6.4 9.6 1.1 8.9 0.1 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Mito_fiss_reg PF05308.11 EMR71521.1 - 5.7 6.9 10.6 8.4 6.4 10.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator adh_short PF00106.25 EMR71522.1 - 0.0013 18.3 0.0 0.0014 18.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71522.1 - 0.0017 18.0 0.1 0.0017 18.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Aldedh PF00171.22 EMR71523.1 - 5.7e-138 460.3 0.0 6.7e-138 460.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMR71523.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Aminotran_1_2 PF00155.21 EMR71524.1 - 1.6e-29 103.2 0.0 2.1e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMR71524.1 - 1.6e-05 23.6 0.0 2.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EMR71524.1 - 0.00041 19.7 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase zf-C2H2_aberr PF17017.5 EMR71525.1 - 0.00078 19.6 3.1 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EMR71525.1 - 0.0033 18.1 17.6 0.39 11.7 2.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EMR71525.1 - 0.023 15.1 18.7 0.055 14.0 0.7 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMR71525.1 - 0.023 15.1 2.5 0.023 15.1 2.5 3.6 4 0 0 4 4 4 0 Zinc-finger double domain Phosphoprotein PF00922.17 EMR71525.1 - 0.072 12.7 0.3 0.16 11.6 0.2 1.5 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein zf-CHCC PF10276.9 EMR71525.1 - 0.14 12.2 0.9 0.31 11.1 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger domain zf-BED PF02892.15 EMR71525.1 - 0.16 12.0 3.6 0.95 9.5 0.3 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 EMR71525.1 - 0.56 10.6 6.7 7 7.1 2.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EMR71525.1 - 6.3 7.2 8.3 73 3.8 1.2 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.32 EMR71527.1 - 2.5e-10 40.8 6.1 0.017 16.0 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR71527.1 - 1.7e-05 25.1 0.1 0.74 10.2 0.0 4.3 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_N PF01194.17 EMR71528.1 - 1.4e-29 102.2 0.6 1.6e-29 101.9 0.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit PLDc_2 PF13091.6 EMR71530.1 - 3.9e-15 55.9 0.0 1.9e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EMR71530.1 - 2.8e-07 30.4 4.6 0.0089 16.2 0.4 3.6 3 1 0 3 3 3 2 Phospholipase D Active site motif Ank_4 PF13637.6 EMR71531.1 - 1.6e-17 63.6 4.5 3.7e-09 36.9 0.2 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR71531.1 - 2.2e-14 53.8 0.2 2.4e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR71531.1 - 8.6e-12 45.1 1.4 7.7e-09 35.6 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EMR71531.1 - 1.8e-11 44.0 0.9 4.7e-07 30.0 0.2 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EMR71531.1 - 3.9e-10 39.1 0.8 1.7e-05 24.8 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat SUIM_assoc PF16619.5 EMR71531.1 - 0.0052 16.8 0.6 0.0091 16.0 0.6 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 SYF2 PF08231.12 EMR71531.1 - 0.0064 16.9 0.0 0.0093 16.4 0.0 1.3 1 0 0 1 1 1 1 SYF2 splicing factor PALP PF00291.25 EMR71532.1 - 1.8e-25 90.0 0.0 2.4e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GST_N_2 PF13409.6 EMR71533.1 - 8.4e-20 70.9 0.1 2.5e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR71533.1 - 3.1e-19 69.1 0.0 5.9e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR71533.1 - 1e-10 41.5 1.0 1.7e-10 40.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMR71533.1 - 1.1e-09 38.5 0.0 2.5e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR71533.1 - 0.00068 19.8 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR71533.1 - 0.0022 18.2 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMR71533.1 - 0.031 14.9 0.0 0.061 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Clr5 PF14420.6 EMR71534.1 - 1.3e-19 70.1 6.9 2e-19 69.5 6.9 1.3 1 0 0 1 1 1 1 Clr5 domain Tox-REase-7 PF15649.6 EMR71534.1 - 0.015 15.6 0.2 0.026 14.8 0.1 1.6 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 7 Arrestin_C PF02752.22 EMR71534.1 - 0.045 14.2 0.7 0.055 13.9 0.7 1.1 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain YjcZ PF13990.6 EMR71534.1 - 0.054 12.9 1.0 0.06 12.7 1.0 1.1 1 0 0 1 1 1 0 YjcZ-like protein Sld3_N PF18523.1 EMR71534.1 - 0.083 13.0 4.4 0.098 12.8 4.4 1.2 1 0 0 1 1 1 0 Sld3 N-terminal domain NDUFA12 PF05071.16 EMR71535.1 - 3.9e-30 104.5 3.8 4.8e-30 104.3 3.8 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 LCCL PF03815.19 EMR71536.1 - 2.2e-22 79.0 0.2 5.5e-22 77.7 0.2 1.6 1 0 0 1 1 1 1 LCCL domain CitMHS PF03600.16 EMR71536.1 - 0.038 13.2 6.0 0.073 12.3 6.0 1.5 1 0 0 1 1 1 0 Citrate transporter Peptidase_M20 PF01546.28 EMR71538.1 - 1.4e-20 73.9 0.1 2.4e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR71538.1 - 1.8e-18 66.4 0.0 3.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain PALP PF00291.25 EMR71538.1 - 7.3e-09 35.4 0.0 7.3e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M28 PF04389.17 EMR71538.1 - 0.0016 18.2 0.2 0.0033 17.2 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M28 TGT PF01702.18 EMR71539.1 - 3.3e-25 89.0 0.2 4.1e-25 88.7 0.2 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase YfiO PF13525.6 EMR71540.1 - 0.071 12.8 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Outer membrane lipoprotein Chromo_2 PF18704.1 EMR71542.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 Aldedh PF00171.22 EMR71543.1 - 3.2e-176 586.4 1.0 3.7e-176 586.2 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HsbA PF12296.8 EMR71544.1 - 9.1e-09 35.8 3.7 9.1e-09 35.8 3.7 2.8 2 1 1 3 3 3 1 Hydrophobic surface binding protein A SET PF00856.28 EMR71545.1 - 6.2e-18 65.7 0.0 1.4e-17 64.6 0.0 1.6 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EMR71545.1 - 5.2e-06 27.2 0.1 2e-05 25.3 0.0 2.1 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding KGG PF10685.9 EMR71547.1 - 9.9e-38 127.3 22.6 2.1e-11 43.7 0.8 4.3 4 0 0 4 4 4 4 Stress-induced bacterial acidophilic repeat motif LEA_5 PF00477.17 EMR71547.1 - 0.074 13.5 7.0 0.11 13.0 7.0 1.4 1 1 0 1 1 1 0 Small hydrophilic plant seed protein IPP-2 PF04979.14 EMR71548.1 - 4.9e-23 82.3 9.2 4.9e-23 82.3 9.2 1.5 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) UvdE PF03851.14 EMR71549.1 - 4.5e-107 357.4 0.0 6.4e-107 356.9 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF3716 PF12511.8 EMR71550.1 - 7.6e-07 29.1 0.1 1.4e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF2076 PF09849.9 EMR71551.1 - 0.0026 17.8 0.1 0.0026 17.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L27 PF01016.19 EMR71552.1 - 3.7e-27 94.1 0.1 8.4e-27 93.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal L27 protein Alk_phosphatase PF00245.20 EMR71553.1 - 1.3e-65 222.0 0.0 2.5e-65 221.1 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EMR71553.1 - 1.9e-05 24.2 0.1 4.1e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EMR71553.1 - 2.9e-05 23.8 0.1 4.8e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EMR71553.1 - 0.0022 16.7 0.2 0.0034 16.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 EMR71553.1 - 0.071 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Metalloenzyme PF01676.18 EMR71553.1 - 0.072 12.4 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Bac_rhamnosid6H PF17389.2 EMR71554.1 - 2.6e-05 23.6 0.3 3.5e-05 23.2 0.3 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain p450 PF00067.22 EMR71555.1 - 0.0028 16.4 0.0 0.0031 16.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_2 PF02230.16 EMR71556.1 - 2.1e-15 57.1 0.0 3.4e-14 53.2 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EMR71556.1 - 0.0013 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EMR71556.1 - 0.0097 16.5 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR71556.1 - 0.031 13.5 0.0 1.5 8.0 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EMR71556.1 - 0.14 12.0 0.0 0.54 10.1 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 EMR71557.1 - 1.1e-122 410.1 27.8 1.3e-122 409.9 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR71557.1 - 2.3e-19 69.5 40.7 4.9e-12 45.4 19.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EHN PF06441.12 EMR71558.1 - 5.9e-26 90.9 0.4 1.9e-25 89.3 0.4 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus ABC_tran PF00005.27 EMR71559.1 - 8.6e-35 120.2 0.0 1.2e-16 61.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR71559.1 - 5.1e-26 91.9 36.4 9.4e-26 91.1 11.0 3.0 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EMR71559.1 - 1.1e-05 25.1 0.9 0.18 11.2 0.0 3.4 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMR71559.1 - 1.4e-05 25.4 0.3 0.27 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EMR71559.1 - 3.8e-05 23.7 0.0 0.13 12.1 0.0 3.2 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMR71559.1 - 0.00013 22.4 0.1 0.33 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EMR71559.1 - 0.00048 19.8 0.7 0.2 11.2 0.0 3.3 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 EMR71559.1 - 0.00062 19.7 0.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EMR71559.1 - 0.001 18.8 0.6 0.97 9.2 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 EMR71559.1 - 0.004 16.7 0.1 0.41 10.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EMR71559.1 - 0.0046 15.9 1.7 0.045 12.7 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 EMR71559.1 - 0.015 15.3 0.0 4.6 7.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 EMR71559.1 - 0.027 13.6 0.1 0.099 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 EMR71559.1 - 0.035 13.8 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EMR71559.1 - 0.037 14.1 0.1 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 EMR71559.1 - 0.041 13.2 0.1 3.5 6.9 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF4257 PF14074.6 EMR71559.1 - 0.077 13.2 0.5 0.32 11.2 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) AAA PF00004.29 EMR71559.1 - 0.085 13.3 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EMR71559.1 - 0.19 11.0 0.3 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 EMR71559.1 - 0.58 10.4 2.1 1.3 9.3 0.2 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Hid1 PF12722.7 EMR71560.1 - 3.1e-204 680.6 0.1 9.6e-100 334.9 0.0 3.0 1 1 2 3 3 3 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EMR71560.1 - 1e-48 166.2 0.0 2.4e-29 102.3 0.0 3.0 1 1 2 3 3 3 3 Dyggve-Melchior-Clausen syndrome protein PBP1_TM PF14812.6 EMR71560.1 - 3.4 8.1 5.3 2.8 8.4 0.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 EMR71561.1 - 5.7e-17 61.7 48.9 8.3e-10 38.1 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMR71561.1 - 0.058 12.7 21.8 2 7.6 0.1 3.9 2 2 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB IF4E PF01652.18 EMR71562.1 - 3.5e-38 130.9 0.2 4.6e-38 130.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Sec8_exocyst PF04048.14 EMR71563.1 - 1e-48 164.8 1.7 3e-48 163.3 1.7 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EMR71563.1 - 3.4e-12 46.2 1.0 7e-12 45.2 1.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex YcbB PF08664.10 EMR71563.1 - 0.066 13.3 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 YcbB domain Bacillus_HBL PF05791.11 EMR71563.1 - 0.22 11.3 3.8 1.1 9.0 1.0 3.1 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Swi5 PF07061.11 EMR71563.1 - 0.37 10.9 2.1 1 9.5 0.2 2.7 3 0 0 3 3 3 0 Swi5 Pkinase PF00069.25 EMR71564.1 - 6.7e-67 225.6 0.0 1e-66 225.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR71564.1 - 2.4e-48 164.7 0.0 3.7e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMR71564.1 - 2e-06 26.8 0.3 5.1e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EMR71564.1 - 7.4e-05 22.2 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Clr5 PF14420.6 EMR71565.1 - 7.2e-10 38.9 0.9 1.3e-09 38.2 0.2 1.7 2 0 0 2 2 2 1 Clr5 domain TPR_2 PF07719.17 EMR71566.1 - 6.8e-29 97.6 18.3 4.7e-05 23.2 0.0 8.6 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 EMR71566.1 - 1.5e-26 91.1 14.0 1.7e-05 24.5 0.6 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EMR71566.1 - 1.4e-20 71.7 1.2 0.0017 18.4 0.2 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMR71566.1 - 1.3e-18 67.1 18.2 7.3e-09 35.8 1.1 7.6 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMR71566.1 - 2.1e-16 59.2 24.8 2.7e-05 24.6 0.0 7.8 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMR71566.1 - 2.1e-15 57.0 14.0 0.0018 18.7 0.2 6.2 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EMR71566.1 - 4.9e-14 52.7 27.1 1.1e-05 26.0 0.1 7.6 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 EMR71566.1 - 4.3e-12 45.5 17.1 0.00036 20.3 0.8 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMR71566.1 - 8.4e-11 41.4 6.6 0.00039 20.0 0.0 5.7 6 0 0 6 6 5 3 TPR repeat TPR_7 PF13176.6 EMR71566.1 - 2e-10 40.0 16.7 0.0065 16.4 0.0 6.9 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EMR71566.1 - 5.5e-08 32.8 11.8 8.4e-05 22.6 2.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EMR71566.1 - 8.9e-06 25.1 5.7 0.0049 16.1 0.1 4.1 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMR71566.1 - 3.6e-05 24.1 18.6 0.24 12.1 0.2 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR71566.1 - 0.00045 20.4 10.9 4.4 7.6 1.4 5.3 4 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EMR71566.1 - 0.00055 20.0 0.3 1.6 9.2 0.0 4.7 5 0 0 5 5 4 1 PPR repeat TPR_17 PF13431.6 EMR71566.1 - 0.00069 19.8 1.3 30 5.3 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EMR71566.1 - 0.0031 17.0 0.1 2.6 7.4 0.0 3.4 3 2 0 4 4 4 1 Coatomer epsilon subunit TPR_4 PF07721.14 EMR71566.1 - 0.0049 17.4 15.3 1.9 9.4 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 EMR71566.1 - 0.028 14.5 2.9 20 5.3 0.0 4.7 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 EMR71566.1 - 0.075 12.4 6.7 0.31 10.4 0.1 3.7 3 1 1 5 5 5 0 MalT-like TPR region HrpB1_HrpK PF09613.10 EMR71566.1 - 0.11 12.2 0.5 1.5 8.4 0.0 2.9 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4810 PF16068.5 EMR71566.1 - 0.11 13.0 0.1 13 6.4 0.0 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF4810) TPR_20 PF14561.6 EMR71566.1 - 0.14 12.5 6.2 7.3 7.0 0.3 4.1 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 EMR71566.1 - 3.7 7.2 10.8 2.2 8.0 0.1 4.1 5 1 1 6 6 6 0 Tetratricopeptide repeat-like domain SNAP PF14938.6 EMR71566.1 - 7.8 5.8 12.4 3.8 6.8 0.1 4.0 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP Transglut_core PF01841.19 EMR71567.1 - 1.1e-11 45.2 0.4 2.8e-11 43.9 0.4 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Abhydrolase_6 PF12697.7 EMR71568.1 - 5.9e-19 69.6 1.9 6.7e-19 69.4 1.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EMR71568.1 - 1.3e-05 24.2 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EMR71568.1 - 0.0006 18.9 0.0 0.00094 18.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 EMR71568.1 - 0.0016 17.7 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMR71568.1 - 0.0098 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EMR71568.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF3220 PF11516.8 EMR71568.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) SLC12 PF03522.15 EMR71569.1 - 6.3 5.7 20.7 8.6 5.3 20.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Myosin_head PF00063.21 EMR71570.1 - 6.5e-237 788.1 5.3 7.7e-237 787.8 5.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EMR71570.1 - 2.3e-47 161.1 0.0 4.3e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EMR71570.1 - 8.2e-13 47.8 0.2 1.6e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMR71570.1 - 1.3e-08 34.6 0.1 3e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMR71570.1 - 4.6e-08 32.6 0.0 1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 EMR71570.1 - 0.0048 16.6 10.0 0.17 11.8 2.4 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif SH3_3 PF08239.11 EMR71570.1 - 0.012 15.8 0.7 0.033 14.5 0.7 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Hpr_kinase_C PF07475.12 EMR71570.1 - 0.014 14.9 0.4 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 EMR71570.1 - 0.052 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain hSH3 PF14603.6 EMR71570.1 - 0.084 13.3 0.1 0.62 10.5 0.0 2.4 2 0 0 2 2 2 0 Helically-extended SH3 domain AAA_16 PF13191.6 EMR71570.1 - 0.088 13.2 0.0 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EMR71570.1 - 0.093 13.3 0.3 0.77 10.3 0.0 2.6 3 0 0 3 3 3 0 ABC transporter NACHT PF05729.12 EMR71570.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SepF PF04472.12 EMR71570.1 - 0.15 12.3 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 Cell division protein SepF DUF4913 PF16259.5 EMR71570.1 - 0.16 12.1 1.1 0.44 10.6 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) Mg_chelatase PF01078.21 EMR71570.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DHHC PF01529.20 EMR71573.1 - 7.4e-30 103.8 0.8 1.2e-29 103.1 0.8 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase HHV-5_US34A PF17087.5 EMR71573.1 - 9.2 6.5 6.7 60 3.9 3.4 2.5 2 0 0 2 2 2 0 Herpesvirus US34A protein family RTA1 PF04479.13 EMR71574.1 - 9.6e-74 247.5 8.9 9.6e-74 247.5 8.9 1.8 1 1 1 2 2 2 1 RTA1 like protein CN_hydrolase PF00795.22 EMR71576.1 - 3.1e-32 111.9 0.1 4.1e-32 111.5 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_8 PF08022.12 EMR71577.1 - 1e-21 77.1 0.0 2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMR71577.1 - 1.1e-21 77.6 0.0 1.8e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EMR71577.1 - 6e-10 39.3 12.1 2.7e-09 37.2 3.0 3.2 1 1 2 3 3 3 2 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EMR71577.1 - 0.036 14.7 0.0 3.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain LrgA PF03788.14 EMR71577.1 - 0.044 13.7 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 LrgA family RRM_1 PF00076.22 EMR71578.1 - 9.8e-13 47.7 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EMR71578.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Amidase PF01425.21 EMR71579.1 - 3.2e-65 220.8 0.1 9.2e-50 169.9 0.0 2.4 2 1 0 2 2 2 2 Amidase RdRP PF05183.12 EMR71580.1 - 3e-99 333.3 0.0 3.7e-99 333.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Ferric_reduct PF01794.19 EMR71582.1 - 7.1e-21 74.6 10.6 7.1e-21 74.6 10.6 2.9 3 1 1 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EMR71582.1 - 1.7e-06 28.6 0.0 2.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMR71582.1 - 6.1e-06 26.4 0.2 0.023 14.8 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR71582.1 - 0.0055 16.8 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 1 FAD-binding domain Atthog PF18800.1 EMR71582.1 - 0.013 15.5 4.1 0.013 15.5 4.1 2.7 2 1 1 3 3 3 0 Attenuator of Hedgehog Bac_rhodopsin PF01036.18 EMR71583.1 - 4.3e-15 55.9 7.3 5e-15 55.7 7.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein AIG2_2 PF13772.6 EMR71584.1 - 1.6e-07 31.6 0.0 2.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 EMR71584.1 - 9.4e-07 29.5 0.0 1.3e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DDE_Tnp_Tn3 PF01526.17 EMR71584.1 - 0.044 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain FAD_binding_3 PF01494.19 EMR71585.1 - 3.3e-09 36.5 1.1 5e-08 32.6 0.8 2.3 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EMR71585.1 - 1.3e-06 28.6 0.0 2.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR71585.1 - 0.00014 21.2 0.0 0.00035 19.9 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR71585.1 - 0.00039 20.9 0.0 0.00094 19.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR71585.1 - 0.0012 18.5 0.0 0.0014 18.3 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR71585.1 - 0.002 17.3 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR71585.1 - 0.0099 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EMR71585.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EMR71585.1 - 0.017 15.2 0.0 0.83 9.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 EMR71585.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 EMR71585.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain Amino_oxidase PF01593.24 EMR71585.1 - 0.19 11.0 0.1 0.39 10.0 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Ank_3 PF13606.6 EMR71586.1 - 6.4e-07 29.2 0.0 1.5 9.7 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EMR71586.1 - 3.5e-06 27.2 0.0 0.065 13.7 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EMR71586.1 - 1.6e-05 25.4 0.0 12 6.6 0.0 4.0 3 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR71586.1 - 0.0011 19.2 0.0 0.87 10.0 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR71586.1 - 0.0028 18.2 0.0 14 6.4 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.7 EMR71587.1 - 1.2e-17 65.3 0.2 3e-17 63.9 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.6 EMR71587.1 - 1e-13 51.4 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMR71587.1 - 6.1e-12 45.4 0.0 1.1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EMR71587.1 - 1.8e-08 35.0 0.0 1.6e-06 28.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR71587.1 - 1.5e-07 32.0 0.1 0.00015 22.3 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EMR71587.1 - 3.2e-07 31.0 0.0 0.00072 20.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EMR71587.1 - 1.5e-06 28.1 0.0 0.00032 20.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EMR71587.1 - 0.0051 16.4 0.2 0.013 15.1 0.1 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.14 EMR71587.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 EMR71587.1 - 0.02 14.7 0.1 0.045 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Chlorophyllase2 PF12740.7 EMR71587.1 - 0.03 13.2 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EMR71587.1 - 0.045 13.4 0.0 6 6.4 0.0 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EMR71587.1 - 0.081 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Peptidase_M55 PF04951.13 EMR71587.1 - 0.22 10.9 0.1 0.39 10.1 0.1 1.3 1 0 0 1 1 1 0 D-aminopeptidase Methyltransf_11 PF08241.12 EMR71588.1 - 3.6e-20 72.4 0.0 7.3e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR71588.1 - 5.4e-18 65.5 0.0 1.1e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR71588.1 - 4.1e-16 59.1 0.0 6.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR71588.1 - 7.7e-13 48.6 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR71588.1 - 1.9e-12 47.7 0.0 3.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR71588.1 - 8.7e-11 41.6 0.0 1.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMR71588.1 - 8.6e-10 38.4 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EMR71588.1 - 6.4e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EMR71588.1 - 0.00093 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EMR71588.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMR71588.1 - 0.0018 18.1 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EMR71588.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 EMR71588.1 - 0.072 12.0 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) PrmA PF06325.13 EMR71588.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 EMR71588.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase APH PF01636.23 EMR71592.1 - 0.0021 18.0 0.5 0.056 13.4 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMR71592.1 - 0.084 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pox_Ag35 PF03286.14 EMR71592.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.5 2 1 0 2 2 2 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 EMR71592.1 - 0.14 12.5 18.5 0.76 10.2 3.7 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain EcKinase PF02958.20 EMR71592.1 - 0.22 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase LAT PF15234.6 EMR71592.1 - 0.42 10.3 7.9 4.6 6.9 3.0 2.5 2 0 0 2 2 2 0 Linker for activation of T-cells FAM176 PF14851.6 EMR71592.1 - 0.46 10.1 7.5 0.29 10.8 0.5 2.6 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 EMR71592.1 - 1.9 8.9 20.7 2.7 8.4 7.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.8 EMR71592.1 - 4.2 8.4 18.0 12 7.0 5.1 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal GCIP PF13324.6 EMR71592.1 - 4.4 6.8 7.9 7.2 6.1 0.8 2.3 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting MFS_1 PF07690.16 EMR71594.1 - 3.1e-05 23.1 6.3 4e-05 22.7 6.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.27 EMR71595.1 - 3.1e-46 157.3 0.0 2.1e-25 89.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR71595.1 - 8e-22 78.2 11.9 4.4e-15 56.1 2.8 2.8 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EMR71595.1 - 5.4e-11 42.4 1.8 0.00044 19.8 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMR71595.1 - 2.5e-07 30.8 0.5 0.036 13.9 0.0 4.2 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EMR71595.1 - 9.4e-06 24.9 0.8 0.081 12.0 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 EMR71595.1 - 0.00015 21.5 1.5 0.15 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMR71595.1 - 0.00034 20.6 1.3 0.0091 15.9 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EMR71595.1 - 0.00077 19.9 0.1 0.076 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EMR71595.1 - 0.00094 19.4 0.2 0.029 14.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMR71595.1 - 0.0012 18.9 1.3 1.2 9.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EMR71595.1 - 0.0019 18.7 0.2 0.69 10.3 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EMR71595.1 - 0.0024 17.6 0.1 0.57 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EMR71595.1 - 0.0027 18.2 0.8 0.29 11.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMR71595.1 - 0.0029 17.9 3.6 0.09 13.0 0.2 3.2 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EMR71595.1 - 0.0038 17.0 1.4 0.39 10.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.6 EMR71595.1 - 0.0073 15.9 0.2 0.23 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Spore_IV_A PF09547.10 EMR71595.1 - 0.0078 15.2 0.5 0.026 13.5 0.1 1.9 2 0 0 2 2 2 1 Stage IV sporulation protein A (spore_IV_A) AAA_18 PF13238.6 EMR71595.1 - 0.019 15.5 0.1 6.9 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMR71595.1 - 0.023 14.2 0.4 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EMR71595.1 - 0.024 13.6 1.1 1.3 7.9 0.3 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 EMR71595.1 - 0.026 13.7 0.8 0.45 9.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 EMR71595.1 - 0.03 14.4 1.4 0.091 12.8 0.3 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 EMR71595.1 - 0.11 12.0 1.6 0.2 11.2 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EMR71595.1 - 0.11 12.5 2.1 0.58 10.2 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AIG1 PF04548.16 EMR71595.1 - 0.12 11.7 3.5 4.9 6.4 0.3 2.8 3 0 0 3 3 3 0 AIG1 family Viral_helicase1 PF01443.18 EMR71595.1 - 0.13 11.9 0.5 2.9 7.6 0.1 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.15 EMR71595.1 - 0.16 10.7 0.3 0.35 9.6 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein Rad17 PF03215.15 EMR71595.1 - 0.16 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 EMR71595.1 - 0.17 12.3 0.1 7.2 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 EMR71595.1 - 0.18 11.6 0.2 12 5.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EMR71595.1 - 0.21 11.6 0.5 11 6.0 0.2 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HET PF06985.11 EMR71596.1 - 6.1e-21 75.3 5.4 2.7e-19 69.9 0.6 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.19 EMR71599.1 - 1.2e-35 123.4 0.0 1.8e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR71599.1 - 1.2e-27 97.2 0.0 2.2e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DUF3161 PF11362.8 EMR71599.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) adh_short_C2 PF13561.6 EMR71601.1 - 1.6e-51 175.1 0.0 1.9e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR71601.1 - 7.3e-42 143.0 0.1 9.3e-42 142.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR71601.1 - 7.9e-09 35.7 0.2 1.1e-08 35.2 0.2 1.1 1 0 0 1 1 1 1 KR domain Hormone_1 PF00103.20 EMR71601.1 - 0.079 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Somatotropin hormone family DFP PF04127.15 EMR71601.1 - 0.19 11.6 2.1 0.33 10.8 0.1 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 EMR71601.1 - 0.35 10.7 1.5 0.37 10.7 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Malectin_like PF12819.7 EMR71602.1 - 0.092 11.9 1.1 0.12 11.5 1.1 1.1 1 0 0 1 1 1 0 Malectin-like domain BTB PF00651.31 EMR71603.1 - 8.2e-06 26.0 0.0 2.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain MazG PF03819.17 EMR71603.1 - 0.065 13.4 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain GATase_6 PF13522.6 EMR71604.1 - 8.4e-13 48.7 0.0 1.8e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EMR71604.1 - 1.5e-11 44.3 0.0 3.3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EMR71604.1 - 3.5e-05 23.4 0.1 6.7e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EMR71604.1 - 0.00013 21.0 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II U62_UL91 PF17442.2 EMR71604.1 - 0.063 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins PA PF02225.22 EMR71604.1 - 0.16 12.0 0.2 0.65 10.1 0.2 2.1 1 1 0 1 1 1 0 PA domain zf-RING_2 PF13639.6 EMR71605.1 - 0.0023 18.2 7.6 0.0023 18.2 7.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EMR71605.1 - 0.0043 16.9 6.7 0.011 15.6 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2407 PF10302.9 EMR71605.1 - 0.028 15.0 0.3 0.65 10.6 0.1 2.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF1272 PF06906.11 EMR71605.1 - 3.2 7.9 7.6 9.7 6.4 7.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) GluR_Homer-bdg PF10606.9 EMR71606.1 - 2.7 8.3 4.8 23 5.3 0.3 2.2 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor Glutaredoxin PF00462.24 EMR71607.1 - 9.8e-14 51.3 0.0 2.1e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EMR71607.1 - 0.015 15.7 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_L2_C PF03947.18 EMR71607.1 - 0.07 13.3 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain Ribonuclease_3 PF00636.26 EMR71608.1 - 1.5e-41 141.3 0.0 3.4e-20 72.6 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EMR71608.1 - 2.6e-28 98.7 0.0 4.5e-12 46.2 0.0 3.5 2 2 1 3 3 3 3 Ribonuclease-III-like COX7a PF02238.15 EMR71608.1 - 0.058 13.8 0.7 0.72 10.3 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII ResIII PF04851.15 EMR71609.1 - 2.2e-15 57.1 0.1 4e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMR71609.1 - 6.4e-13 48.8 0.0 1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMR71609.1 - 0.051 13.8 0.1 0.32 11.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain Peptidase_S8 PF00082.22 EMR71610.1 - 1e-33 116.9 6.2 2.4e-33 115.7 6.2 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR71610.1 - 3.3e-13 50.1 0.0 5.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 TAP42 PF04177.12 EMR71612.1 - 9.1e-109 363.4 0.6 1e-108 363.3 0.6 1.0 1 0 0 1 1 1 1 TAP42-like family GRDP-like PF07173.12 EMR71612.1 - 0.06 14.0 0.2 0.63 10.7 0.2 2.3 1 1 1 2 2 2 0 Glycine-rich domain-containing protein-like PhoD PF09423.10 EMR71613.1 - 1.9e-104 349.4 0.5 2.4e-104 349.1 0.5 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EMR71613.1 - 2.2e-30 105.0 0.2 5.3e-30 103.8 0.2 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EMR71613.1 - 0.024 15.2 0.5 0.057 14.0 0.5 1.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain RE_Bsp6I PF09504.10 EMR71613.1 - 0.12 11.9 0.1 0.51 9.9 0.1 1.9 2 0 0 2 2 2 0 Bsp6I restriction endonuclease 2-Hacid_dh_C PF02826.19 EMR71614.1 - 4.3e-53 179.3 0.0 5.7e-53 178.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMR71614.1 - 2.8e-18 65.9 0.0 1e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMR71614.1 - 6.8e-07 29.6 0.1 1.1e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EMR71614.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EMR71614.1 - 0.028 15.0 0.1 0.052 14.1 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CHASE2 PF05226.11 EMR71614.1 - 0.034 13.9 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 CHASE2 domain XdhC_C PF13478.6 EMR71614.1 - 0.039 14.5 0.2 0.094 13.2 0.2 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Epimerase PF01370.21 EMR71615.1 - 5.4e-17 62.0 0.0 6.4e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR71615.1 - 2.2e-09 37.2 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMR71615.1 - 3e-07 29.7 0.0 4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMR71615.1 - 9.3e-07 28.2 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EMR71615.1 - 0.00093 18.4 0.0 0.07 12.3 0.0 2.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EMR71615.1 - 0.01 15.3 0.0 0.025 14.0 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.6 EMR71615.1 - 0.1 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 EMR71615.1 - 0.18 11.7 0.0 0.5 10.2 0.0 1.7 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EMR71615.1 - 0.23 10.5 0.0 1.8 7.6 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F-box_4 PF15966.5 EMR71616.1 - 0.35 10.8 1.9 0.72 9.7 0.3 2.3 2 1 1 3 3 3 0 F-box CDC73_C PF05179.14 EMR71618.1 - 2e-58 196.5 0.0 3.1e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal NmrA PF05368.13 EMR71619.1 - 0.027 14.0 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Cellulase PF00150.18 EMR71620.1 - 1.4e-17 64.0 4.1 1.9e-17 63.6 4.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Antig_Caf1 PF09255.10 EMR71620.1 - 0.2 11.8 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Caf1 Capsule antigen SGL PF08450.12 EMR71621.1 - 9.3e-17 61.4 1.6 2.5e-16 60.0 1.4 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Cohesin PF00963.18 EMR71624.1 - 0.11 12.7 0.4 0.48 10.7 0.3 1.8 1 1 1 2 2 2 0 Cohesin domain EHN PF06441.12 EMR71626.1 - 3.4e-33 114.3 0.1 7e-33 113.2 0.1 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMR71626.1 - 1.9e-16 60.5 0.1 2.3e-15 56.9 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR71626.1 - 1.4e-06 29.1 0.6 5.2e-06 27.2 0.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glutaredoxin PF00462.24 EMR71627.1 - 1.3e-17 63.8 0.0 1.2e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EMR71627.1 - 1.8e-12 47.1 0.0 5e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EMR71627.1 - 0.13 12.6 0.0 11 6.5 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like CoatB PF10389.9 EMR71628.1 - 0.1 12.5 1.2 0.26 11.1 1.2 1.7 1 0 0 1 1 1 0 Bacteriophage coat protein B LSM PF01423.22 EMR71629.1 - 7.9e-17 60.7 0.3 1e-16 60.3 0.3 1.2 1 0 0 1 1 1 1 LSM domain IU_nuc_hydro PF01156.19 EMR71630.1 - 1.8e-55 188.7 0.0 2.9e-55 188.0 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cactin_mid PF10312.9 EMR71631.1 - 5.6e-61 205.7 6.1 8.2e-61 205.2 6.1 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EMR71631.1 - 5.2e-51 171.8 2.7 9.5e-51 171.0 2.7 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 EMR71631.1 - 0.0055 17.0 0.0 0.032 14.6 0.0 2.3 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 EMR71631.1 - 0.04 13.9 0.5 0.04 13.9 0.5 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF3632 PF12311.8 EMR71632.1 - 2.2e-36 125.9 1.0 3.1e-36 125.4 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF4160 PF13711.6 EMR71632.1 - 0.17 12.2 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Slx4 PF09494.10 EMR71633.1 - 2e-23 82.1 0.0 4.2e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease MOFRL PF05161.13 EMR71633.1 - 0.13 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 MOFRL family FAD_binding_7 PF03441.14 EMR71634.1 - 1.6e-82 275.9 0.4 3.2e-82 274.9 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EMR71634.1 - 7.4e-36 123.6 0.1 1.2e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 EMR71634.1 - 0.016 15.8 0.3 0.04 14.4 0.3 1.7 1 0 0 1 1 1 0 Universal stress protein family adh_short PF00106.25 EMR71635.1 - 1.9e-18 66.6 0.0 4e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71635.1 - 4.9e-12 45.9 0.0 2.9e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71635.1 - 3.2e-05 23.9 0.1 7.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 KR domain PEP_mutase PF13714.6 EMR71636.1 - 7.4e-39 133.6 0.2 7.4e-37 127.1 0.2 2.1 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EMR71636.1 - 1e-09 37.4 0.2 1.5e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 EMR71636.1 - 0.00016 21.1 0.2 0.054 12.9 0.0 2.2 1 1 1 2 2 2 2 Ketopantoate hydroxymethyltransferase Sua5_yciO_yrdC PF01300.18 EMR71636.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Telomere recombination Ribosomal_S21e PF01249.18 EMR71637.1 - 1e-39 134.5 0.1 1.2e-39 134.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_hydro2_C5 PF18565.1 EMR71637.1 - 0.075 12.9 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 MFS_1 PF07690.16 EMR71638.1 - 2.7e-25 89.0 47.8 2.7e-25 89.0 47.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EMR71639.1 - 2.6e-19 69.4 19.0 6.4e-19 68.1 18.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_2 PF10746.9 EMR71639.1 - 0.044 13.4 0.5 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II FtsJ PF01728.19 EMR71640.1 - 1.5e-54 184.8 0.0 2.3e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EMR71640.1 - 8e-41 139.6 7.2 1.3e-40 138.9 7.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) DUF4519 PF15012.6 EMR71640.1 - 0.0032 17.6 0.3 0.0064 16.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) Methyltransf_23 PF13489.6 EMR71640.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EMR71640.1 - 0.067 12.8 0.0 0.067 12.8 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF2623 PF11115.8 EMR71640.1 - 0.17 12.0 0.1 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) SnoaL PF07366.12 EMR71641.1 - 2.4e-23 82.3 0.0 8.1e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EMR71641.1 - 2.6e-12 47.3 0.1 3.7e-06 27.5 0.1 2.2 2 0 0 2 2 2 2 SnoaL-like domain DUF4722 PF15849.5 EMR71641.1 - 0.093 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) DUF2724 PF10893.8 EMR71641.1 - 0.14 12.0 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2724) His_Phos_2 PF00328.22 EMR71642.1 - 5.3e-10 39.2 0.0 4.9e-06 26.1 0.0 3.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) SUN PF03856.13 EMR71643.1 - 3.1e-33 115.3 0.3 3.7e-33 115.0 0.3 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Sugar_tr PF00083.24 EMR71644.1 - 8e-117 390.9 26.8 9.7e-117 390.6 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR71644.1 - 3.6e-17 62.3 41.9 1.7e-16 60.1 39.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 EMR71644.1 - 0.0018 17.4 4.6 0.0018 17.4 4.6 1.5 2 0 0 2 2 2 1 PUCC protein TRI12 PF06609.13 EMR71644.1 - 0.025 13.0 6.7 0.016 13.7 2.4 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 EMR71644.1 - 0.029 14.6 2.2 0.029 14.6 2.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) TMEM132D_C PF15706.5 EMR71644.1 - 0.17 11.7 0.0 0.53 10.1 0.0 1.8 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Cupin_1 PF00190.22 EMR71645.1 - 1.1e-15 57.6 1.1 1.1e-15 57.6 1.1 1.6 2 0 0 2 2 2 1 Cupin Med26 PF08711.11 EMR71645.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Cupin_2 PF07883.11 EMR71645.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Helo_like_N PF17111.5 EMR71649.1 - 4.9e-12 45.6 1.7 7.9e-12 45.0 1.7 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 EMR71649.1 - 2.6e-08 33.9 0.3 1.3e-07 31.7 0.1 2.2 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EMR71649.1 - 0.00012 22.5 0.6 0.00098 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMR71649.1 - 0.00019 21.7 0.2 0.0049 17.1 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA PF00004.29 EMR71649.1 - 0.0037 17.7 0.5 0.04 14.3 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EMR71649.1 - 0.0052 16.5 0.1 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein RPW8 PF05659.11 EMR71649.1 - 0.041 13.6 0.6 3 7.5 0.0 2.7 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 APS_kinase PF01583.20 EMR71649.1 - 0.048 13.5 0.1 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase BLOC1_2 PF10046.9 EMR71649.1 - 0.052 13.8 2.6 10 6.5 0.0 3.1 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 EMR71649.1 - 0.085 12.9 1.9 7.2 6.6 0.0 2.7 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 EMR71649.1 - 0.12 12.8 3.5 0.72 10.3 0.5 2.9 2 1 0 2 2 2 0 Snapin/Pallidin RNA_helicase PF00910.22 EMR71649.1 - 0.18 12.2 0.0 0.67 10.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase RasGAP_C PF03836.15 EMR71649.1 - 0.19 11.9 1.9 0.33 11.1 0.1 2.2 2 0 0 2 2 2 0 RasGAP C-terminus ABC2_membrane PF01061.24 EMR71650.1 - 2.4e-26 92.5 25.8 3.2e-26 92.1 25.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EMR71650.1 - 1.7e-23 83.7 0.0 3.3e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMR71650.1 - 3.1e-06 27.2 0.0 0.00014 21.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EMR71650.1 - 1e-05 25.2 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR71650.1 - 1.3e-05 25.7 0.1 2.6e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EMR71650.1 - 0.00084 19.2 0.0 0.67 9.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMR71650.1 - 0.001 19.3 0.0 0.0037 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain PDR_CDR PF06422.12 EMR71650.1 - 0.0032 17.3 1.6 0.0063 16.4 0.0 2.4 2 1 1 3 3 2 1 CDR ABC transporter Rad17 PF03215.15 EMR71650.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EMR71650.1 - 0.0077 16.7 0.0 0.064 13.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EMR71650.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EMR71650.1 - 0.016 14.6 0.0 0.063 12.7 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 EMR71650.1 - 0.02 14.5 0.4 0.071 12.7 0.1 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EMR71650.1 - 0.036 14.0 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EMR71650.1 - 0.037 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EMR71650.1 - 0.044 13.5 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMR71650.1 - 0.046 14.3 0.0 0.09 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMR71650.1 - 0.069 13.2 0.0 0.069 13.2 0.0 2.1 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EMR71650.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMR71650.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EMR71650.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SSP160 PF06933.11 EMR71650.1 - 0.25 9.5 7.8 0.36 9.0 7.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ABC2_membrane_3 PF12698.7 EMR71650.1 - 3.7 6.6 24.3 9.3 5.2 24.3 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3439 PF11921.8 EMR71650.1 - 5.6 7.0 12.5 16 5.5 12.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.24 EMR71651.1 - 3.4e-81 273.4 24.9 4.3e-81 273.1 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR71651.1 - 1.6e-30 106.3 56.1 4.3e-25 88.4 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMR71651.1 - 0.23 9.7 18.9 0.0092 14.3 3.7 3.3 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 EMR71652.1 - 4e-08 33.3 9.3 7.9e-08 32.3 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMR71652.1 - 1.5e-06 27.3 0.6 4.1e-06 25.9 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain INTAP PF16617.5 EMR71652.1 - 0.067 13.5 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region NinF PF05810.12 EMR71652.1 - 3.9 7.4 6.0 3.9 7.4 1.8 2.5 2 0 0 2 2 2 0 NinF protein Amidase PF01425.21 EMR71653.1 - 6.9e-100 335.1 0.0 3.7e-99 332.7 0.0 1.8 1 1 0 1 1 1 1 Amidase Zn_clus PF00172.18 EMR71654.1 - 1.2e-09 38.1 7.3 2.3e-09 37.2 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR71654.1 - 3.9e-05 22.8 0.0 8.1e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAN_4 PF14295.6 EMR71655.1 - 0.039 13.9 0.3 0.085 12.8 0.3 1.6 1 0 0 1 1 1 0 PAN domain PAN_1 PF00024.26 EMR71655.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 PAN domain MFS_1 PF07690.16 EMR71656.1 - 1.5e-34 119.5 19.6 1.5e-34 119.5 19.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR71656.1 - 2e-06 27.4 0.5 2e-06 27.4 0.5 2.7 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Spin-Ssty PF02513.17 EMR71656.1 - 0.033 13.9 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 Spin/Ssty Family ADH_zinc_N_2 PF13602.6 EMR71657.1 - 5.2e-30 105.2 0.0 9.7e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMR71657.1 - 6.3e-19 68.3 0.2 1.5e-18 67.0 0.2 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR71657.1 - 0.00078 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EMR71657.1 - 0.32 10.2 2.2 0.46 9.7 0.7 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MmgE_PrpD PF03972.14 EMR71658.1 - 3e-118 395.1 4.3 3.6e-118 394.9 4.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family NicO PF03824.16 EMR71659.1 - 3.9e-56 190.5 3.3 4.5e-41 141.0 0.0 2.2 1 1 1 2 2 2 2 High-affinity nickel-transport protein DUF1230 PF06799.11 EMR71659.1 - 0.028 14.5 0.3 2.9 8.0 0.2 2.3 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 Kelch_1 PF01344.25 EMR71660.1 - 3.4e-44 148.2 14.3 1.9e-10 40.2 0.0 7.1 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EMR71660.1 - 9.3e-40 133.7 6.9 7.5e-09 35.6 0.0 7.0 6 2 1 7 7 7 6 Kelch motif Kelch_4 PF13418.6 EMR71660.1 - 9.2e-27 92.8 4.4 1.1e-05 25.3 0.0 6.1 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EMR71660.1 - 1.8e-26 91.1 2.0 1.2e-05 25.0 0.0 7.0 6 2 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EMR71660.1 - 3.3e-24 84.6 12.8 1.6e-06 28.2 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EMR71660.1 - 7.2e-17 61.0 5.5 0.003 17.5 0.0 5.8 6 0 0 6 6 6 4 Kelch motif PLAC8 PF04749.17 EMR71662.1 - 5.6e-19 69.0 3.3 7.6e-19 68.6 3.3 1.1 1 0 0 1 1 1 1 PLAC8 family JCAD PF15351.6 EMR71662.1 - 0.36 8.6 1.7 0.44 8.3 1.7 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease UPF0086 PF01868.16 EMR71666.1 - 0.062 13.2 0.2 9.7 6.2 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function UPF0086 Harakiri PF15196.6 EMR71666.1 - 0.67 10.5 11.8 2.8 8.5 1.9 2.4 2 1 0 2 2 2 0 Activator of apoptosis harakiri NRIP1_repr_3 PF15689.5 EMR71666.1 - 1.4 9.3 6.6 7.9 6.9 0.5 2.5 1 1 1 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 p450 PF00067.22 EMR71667.1 - 6.5e-45 153.7 0.0 6.2e-44 150.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 2_5_RNA_ligase2 PF13563.6 EMR71667.1 - 0.14 12.1 0.0 0.47 10.4 0.0 1.7 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily DUF3246 PF11596.8 EMR71668.1 - 0.49 9.8 15.6 0.081 12.3 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 EMR71668.1 - 4.5 6.9 17.2 4.7 6.9 10.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 EMR71668.1 - 5.1 6.7 5.8 1.1 8.9 2.2 1.7 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 EMR71668.1 - 5.4 7.5 20.9 2.6 8.5 11.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain UQ_con PF00179.26 EMR71669.1 - 2.6e-07 30.4 0.0 4.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.7 EMR71669.1 - 0.0025 17.7 0.1 0.0057 16.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like RWD PF05773.22 EMR71669.1 - 0.044 14.1 0.1 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 RWD domain Cnd1 PF12717.7 EMR71669.1 - 0.11 12.6 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Glyco_hydro_10 PF00331.20 EMR71670.1 - 1.8e-59 201.4 1.5 2.2e-59 201.2 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GYF_2 PF14237.6 EMR71670.1 - 0.035 13.9 0.2 0.095 12.5 0.2 1.8 1 0 0 1 1 1 0 GYF domain 2 AAA PF00004.29 EMR71671.1 - 7.2e-16 58.8 0.0 1.8e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMR71671.1 - 0.036 14.3 0.4 0.22 11.8 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 EMR71671.1 - 0.041 14.3 0.1 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 EMR71671.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sel1 PF08238.12 EMR71673.1 - 2.1e-32 110.8 38.4 6.4e-05 23.5 0.8 11.9 13 0 0 13 13 13 7 Sel1 repeat GRP PF07172.11 EMR71673.1 - 0.0014 19.2 3.1 0.0043 17.7 3.1 1.9 1 0 0 1 1 1 1 Glycine rich protein family TPR_7 PF13176.6 EMR71673.1 - 0.032 14.3 5.0 0.64 10.2 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SARAF PF06682.12 EMR71673.1 - 0.046 13.4 0.1 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis OPA3 PF07047.12 EMR71673.1 - 0.11 12.3 0.6 0.23 11.2 0.6 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) HemX PF04375.14 EMR71673.1 - 0.64 9.2 7.7 1.1 8.5 7.7 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TPR_8 PF13181.6 EMR71673.1 - 1.8 9.0 6.8 19 5.8 0.2 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.20 EMR71674.1 - 0.0016 18.9 0.0 0.0036 17.7 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily XPG_N PF00752.17 EMR71675.1 - 0.13 12.8 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 XPG N-terminal domain WD40 PF00400.32 EMR71676.1 - 9.6e-06 26.3 1.4 0.051 14.5 0.2 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EMR71676.1 - 0.021 13.8 0.1 1.4 7.8 0.0 2.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FRG1 PF06229.12 EMR71677.1 - 1.7e-45 155.1 0.1 2.7e-45 154.4 0.1 1.3 1 0 0 1 1 1 1 FRG1-like domain Pkinase PF00069.25 EMR71678.1 - 7.9e-71 238.5 0.0 1.3e-70 237.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR71678.1 - 1.8e-37 129.0 0.0 4.4e-37 127.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR71678.1 - 0.00029 20.2 0.0 0.00055 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMR71678.1 - 0.018 14.4 0.4 0.049 13.0 0.4 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMR71678.1 - 0.029 13.2 1.0 0.049 12.4 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 EMR71678.1 - 0.055 12.4 0.1 0.16 10.9 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EMR71678.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family gp37_C PF12604.8 EMR71680.1 - 0.48 10.1 19.1 0.69 9.6 2.2 3.1 1 1 2 3 3 3 0 Tail fibre protein gp37 C terminal PAP2 PF01569.21 EMR71681.1 - 4.6e-13 49.1 5.5 5.3e-13 48.9 4.0 1.9 1 1 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 EMR71681.1 - 9.2e-05 21.9 2.7 9.2e-05 21.9 2.7 1.8 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF212 PF02681.14 EMR71681.1 - 0.0065 16.6 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family VapB_antitoxin PF09957.9 EMR71681.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB DUF3328 PF11807.8 EMR71682.1 - 1.5e-38 132.8 0.1 1.8e-38 132.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1877 PF08974.10 EMR71682.1 - 0.063 13.4 0.1 5.5 7.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1877) Abhydrolase_4 PF08386.10 EMR71683.1 - 1.7e-17 63.4 0.0 3.8e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EMR71683.1 - 1.6e-11 44.4 0.0 2.1e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pyr_redox_2 PF07992.14 EMR71684.1 - 2e-34 119.2 0.2 2.7e-34 118.7 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR71684.1 - 4.9e-11 43.0 0.7 2.1e-07 31.4 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR71684.1 - 1.2e-05 25.4 0.6 0.19 11.7 0.0 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 EMR71684.1 - 1.8e-05 24.5 0.6 0.63 9.6 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 EMR71684.1 - 0.00013 22.3 0.0 0.047 13.9 0.0 2.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain K_oxygenase PF13434.6 EMR71684.1 - 0.0028 16.9 0.1 0.094 11.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EMR71684.1 - 0.0061 16.8 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 EMR71684.1 - 0.0087 15.2 0.2 0.35 9.9 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein ThiF PF00899.21 EMR71684.1 - 0.068 12.5 0.3 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 ThiF family DUF1194 PF06707.11 EMR71684.1 - 0.077 12.2 0.4 0.11 11.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) IBR PF01485.21 EMR71685.1 - 7.5e-08 32.5 14.2 6e-07 29.6 0.2 3.2 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EMR71685.1 - 2.6e-05 24.5 7.6 6.2e-05 23.2 7.4 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EMR71685.1 - 0.00032 20.6 5.7 0.00032 20.6 5.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMR71685.1 - 0.00034 20.4 7.9 0.00097 19.0 7.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMR71685.1 - 0.0029 17.3 7.4 0.0029 17.3 7.4 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EMR71685.1 - 0.0034 17.3 8.8 0.0076 16.2 8.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMR71685.1 - 0.012 15.4 6.3 0.029 14.2 6.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMR71685.1 - 0.091 12.9 7.9 0.038 14.1 4.5 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EMR71685.1 - 0.11 12.4 7.1 2.5 8.0 7.2 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Sterol_MT_C PF08498.10 EMR71686.1 - 6.3e-28 96.9 0.4 1.1e-27 96.1 0.4 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EMR71686.1 - 4.3e-21 75.4 0.0 8e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR71686.1 - 5.6e-20 71.9 0.0 1.2e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR71686.1 - 3e-18 66.0 0.0 4.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMR71686.1 - 2.9e-12 46.5 0.1 4e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EMR71686.1 - 3.1e-12 46.6 0.0 5.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR71686.1 - 3.6e-11 42.8 0.0 6.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMR71686.1 - 9.6e-11 42.3 0.0 3.1e-10 40.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 EMR71686.1 - 0.00026 20.5 0.1 0.00091 18.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EMR71686.1 - 0.00033 20.5 0.1 0.00052 19.8 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EMR71686.1 - 0.00088 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 EMR71686.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 EMR71686.1 - 0.0015 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 EMR71686.1 - 0.0016 17.1 0.0 0.0023 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 EMR71686.1 - 0.0019 17.8 0.0 0.0045 16.6 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW TehB PF03848.14 EMR71686.1 - 0.03 13.7 0.1 0.052 13.0 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EMR71686.1 - 0.031 14.3 0.4 0.072 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 EMR71686.1 - 0.045 13.0 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain PA PF02225.22 EMR71687.1 - 1.1e-11 44.6 0.1 7.3e-11 41.9 0.0 2.4 2 0 0 2 2 2 1 PA domain DUF4449 PF14613.6 EMR71687.1 - 0.14 12.2 1.6 0.35 11.0 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) CoA_transf_3 PF02515.17 EMR71688.1 - 6.4e-32 111.1 0.0 1.3e-29 103.5 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III ADH_N PF08240.12 EMR71689.1 - 0.00065 19.6 0.0 0.0028 17.5 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR71689.1 - 0.0025 17.8 0.1 0.0044 17.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 EMR71689.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Vezatin PF12632.7 EMR71690.1 - 2.5e-39 135.3 0.2 3.5e-39 134.8 0.2 1.2 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes KH_1 PF00013.29 EMR71691.1 - 1.4e-39 133.8 8.9 2.5e-18 65.6 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EMR71691.1 - 2.6e-11 43.2 7.5 0.0035 17.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EMR71691.1 - 1.6e-05 24.7 1.0 0.37 10.7 0.1 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 EMR71691.1 - 0.00039 20.3 0.0 0.033 14.2 0.0 2.5 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 EMR71691.1 - 0.002 18.1 10.3 0.38 10.9 0.4 3.4 3 0 0 3 3 3 3 NusA-like KH domain GPI-anchored PF10342.9 EMR71692.1 - 2.1e-18 66.9 0.1 4.3e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HA2 PF04408.23 EMR71693.1 - 1e-19 70.8 0.0 5.7e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMR71693.1 - 1.3e-11 44.8 0.0 3.3e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMR71693.1 - 1.6e-10 41.2 0.1 7.3e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EMR71693.1 - 1.1e-06 28.5 0.0 2.7e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMR71693.1 - 0.00017 21.9 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMR71693.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Kinesin PF00225.23 EMR71693.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain AAA_16 PF13191.6 EMR71693.1 - 0.12 12.8 0.3 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EMR71693.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EMR71693.1 - 0.15 11.4 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ERAP1_C PF11838.8 EMR71694.1 - 1.5e-86 290.8 0.0 7.4e-86 288.5 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EMR71694.1 - 3.1e-84 281.9 0.3 5.6e-84 281.1 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EMR71694.1 - 2.3e-51 174.6 2.1 2.3e-51 174.6 2.1 1.5 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EMR71694.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) PCNA_N PF00705.18 EMR71695.1 - 1.3e-51 173.6 7.3 1.4e-49 167.0 2.0 2.6 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EMR71695.1 - 2.1e-49 166.9 0.1 4.5e-49 165.9 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EMR71695.1 - 8.2e-10 38.6 0.1 1.1e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EMR71695.1 - 7e-05 22.0 0.4 0.0002 20.6 0.4 1.7 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 EMR71695.1 - 0.012 14.7 0.2 0.058 12.5 0.2 2.1 1 1 0 1 1 1 0 Hus1-like protein DNA_pol3_beta_3 PF02768.15 EMR71695.1 - 0.027 14.3 0.3 0.085 12.7 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain dUTPase PF00692.19 EMR71696.1 - 1.3e-43 147.8 0.0 1.8e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 dUTPase Med13_C PF06333.12 EMR71696.1 - 1.4 8.1 9.3 1.6 8.0 9.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain AJAP1_PANP_C PF15298.6 EMR71696.1 - 3.2 7.9 15.6 5 7.3 15.6 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Shisa PF13908.6 EMR71696.1 - 9.6 6.4 7.6 14 5.9 7.6 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Methyltransf_16 PF10294.9 EMR71698.1 - 0.0054 16.5 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Nsp1_C PF05064.13 EMR71699.1 - 4e-35 120.1 8.1 4e-35 120.1 6.5 1.8 1 1 1 2 2 2 1 Nsp1-like C-terminal region V-SNARE PF05008.15 EMR71699.1 - 0.0057 17.0 4.0 2 8.9 0.1 3.3 2 1 1 3 3 3 2 Vesicle transport v-SNARE protein N-terminus DUF16 PF01519.16 EMR71699.1 - 0.0075 16.7 4.7 0.1 13.1 0.3 2.8 1 1 2 3 3 3 1 Protein of unknown function DUF16 DUF3416 PF11896.8 EMR71699.1 - 0.011 16.0 1.7 0.023 15.0 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) Nup88 PF10168.9 EMR71699.1 - 0.024 12.5 1.0 0.03 12.2 1.0 1.2 1 0 0 1 1 1 0 Nuclear pore component AAA_13 PF13166.6 EMR71699.1 - 0.027 13.1 1.7 0.034 12.8 0.4 1.7 1 1 1 2 2 2 0 AAA domain HIP1_clath_bdg PF16515.5 EMR71699.1 - 0.037 14.6 5.8 0.6 10.8 0.0 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 WXG100 PF06013.12 EMR71699.1 - 0.067 13.4 6.2 1.3 9.3 0.1 3.5 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Med30 PF11315.8 EMR71699.1 - 0.072 13.3 0.8 0.15 12.2 0.8 1.7 1 1 0 1 1 1 0 Mediator complex subunit 30 DUF3450 PF11932.8 EMR71699.1 - 0.091 12.0 9.2 1.1 8.6 2.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 EMR71699.1 - 0.097 12.9 2.5 0.34 11.2 0.4 2.6 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cob_adeno_trans PF01923.18 EMR71699.1 - 0.22 11.6 1.8 1.2 9.3 0.8 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF1664 PF07889.12 EMR71699.1 - 0.3 11.1 3.0 2.2 8.3 0.1 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EMR71699.1 - 0.37 11.3 4.1 1.6 9.3 0.0 3.0 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 EMR71699.1 - 0.4 11.1 6.1 15 6.0 0.4 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 EMR71699.1 - 0.43 10.6 5.0 0.86 9.6 0.4 2.5 2 2 0 2 2 2 0 Laminin Domain II BRE1 PF08647.11 EMR71699.1 - 0.47 10.6 6.8 0.22 11.6 0.6 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4200 PF13863.6 EMR71699.1 - 0.57 10.6 6.8 2.7 8.4 1.2 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4200) KxDL PF10241.9 EMR71699.1 - 0.73 10.2 3.1 12 6.2 0.0 3.4 3 1 1 4 4 4 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 EMR71699.1 - 1.6 9.3 5.5 6.8 7.3 1.4 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 EMR71699.1 - 3.8 8.0 11.0 3.6 8.1 3.3 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Mitoc_mL59 PF18126.1 EMR71700.1 - 1.3e-33 116.1 0.1 1.3e-33 116.1 0.1 2.2 2 1 0 2 2 2 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 EMR71700.1 - 1.6e-16 59.8 1.5 3e-16 58.9 1.5 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EMR71700.1 - 6.9e-12 45.3 2.2 7.7e-06 25.9 0.2 3.2 3 0 0 3 3 3 2 DnaJ domain Mucin PF01456.17 EMR71700.1 - 0.47 10.4 17.0 0.024 14.6 6.0 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Menin PF05053.13 EMR71700.1 - 0.68 8.2 12.0 1 7.6 7.3 2.1 2 0 0 2 2 2 0 Menin Phos_pyr_kin PF08543.12 EMR71701.1 - 2.5e-10 40.2 0.0 4.6e-10 39.3 0.0 1.4 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EMR71701.1 - 1.2e-06 28.1 0.4 5.1e-06 26.0 0.0 2.1 2 1 1 3 3 3 1 pfkB family carbohydrate kinase 14-3-3 PF00244.20 EMR71702.1 - 3.3e-107 357.0 2.9 3.9e-107 356.8 2.9 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EMR71702.1 - 0.083 13.2 0.9 0.43 10.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Rab5ip PF07019.12 EMR71703.1 - 6.6e-28 97.1 9.9 7.8e-28 96.9 9.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) UbiA PF01040.18 EMR71703.1 - 0.14 11.4 6.4 0.21 10.9 6.4 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family IATP PF04568.12 EMR71704.1 - 1.3e-28 99.3 1.4 1.4e-28 99.1 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Complex1_LYR_2 PF13233.6 EMR71705.1 - 9.4e-17 61.5 0.0 9.4e-17 61.5 0.0 2.9 3 1 0 3 3 3 1 Complex1_LYR-like Complex1_LYR PF05347.15 EMR71705.1 - 9e-08 32.1 0.0 2.4e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) N6_Mtase PF02384.16 EMR71705.1 - 0.0056 16.0 0.9 0.0082 15.5 0.2 1.5 2 0 0 2 2 2 1 N-6 DNA Methylase V-SNARE_C PF12352.8 EMR71705.1 - 0.006 16.8 1.7 0.1 12.9 0.3 2.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF948 PF06103.11 EMR71705.1 - 0.12 12.7 1.2 4.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GTP_EFTU PF00009.27 EMR71706.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NAD_binding_8 PF13450.6 EMR71707.1 - 1.4e-09 38.1 0.0 3.4e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EMR71707.1 - 6.4e-09 34.8 0.0 1.6e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMR71707.1 - 0.00049 19.4 0.0 0.33 10.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMR71707.1 - 0.00094 18.5 0.0 0.047 12.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR71707.1 - 0.061 12.6 0.1 0.9 8.7 0.1 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR71707.1 - 0.19 11.7 0.2 5.3 7.0 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.16 EMR71708.1 - 5e-27 94.7 39.1 5.9e-21 74.8 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.9 EMR71708.1 - 0.11 12.7 1.7 1 9.6 0.0 2.6 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HCV_core PF01542.18 EMR71708.1 - 7.5 7.0 8.0 4.9 7.6 0.1 4.0 4 0 0 4 4 4 0 Hepatitis C virus core protein CENP-K PF11802.8 EMR71709.1 - 4.7e-11 42.8 0.9 3.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Centromere-associated protein K BST2 PF16716.5 EMR71709.1 - 0.0077 16.8 4.3 0.0077 16.8 4.3 2.6 3 1 1 4 4 4 1 Bone marrow stromal antigen 2 MAT1 PF06391.13 EMR71709.1 - 0.14 11.9 12.5 0.67 9.7 5.4 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4837 PF16125.5 EMR71709.1 - 0.59 9.1 3.1 0.26 10.3 1.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4837) Cnn_1N PF07989.11 EMR71709.1 - 1.2 9.3 12.4 0.59 10.3 1.1 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Fib_alpha PF08702.10 EMR71709.1 - 1.5 9.0 7.9 0.42 10.8 4.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EMR71709.1 - 2.5 6.9 12.9 0.069 12.0 5.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Cytochrom_B562 PF07361.11 EMR71709.1 - 3.6 8.3 9.0 1 10.0 3.4 2.3 2 0 0 2 2 2 0 Cytochrome b562 Syntaxin-6_N PF09177.11 EMR71709.1 - 5.2 7.7 11.1 9.1 6.9 3.3 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Atg14 PF10186.9 EMR71709.1 - 9.6 5.2 17.9 0.65 9.0 5.8 2.1 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DEAD PF00270.29 EMR71710.1 - 3.9e-49 166.8 0.0 1.7e-48 164.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR71710.1 - 6.7e-28 97.3 0.0 3.1e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR71710.1 - 6.2e-06 26.3 0.0 1.7e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 EMR71710.1 - 0.0013 19.2 4.2 0.0013 19.2 4.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2986) PRAI PF00697.22 EMR71710.1 - 0.029 14.1 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CMS1 PF14617.6 EMR71710.1 - 0.032 13.6 0.0 0.032 13.6 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit SpoU_methylase PF00588.19 EMR71710.1 - 0.14 12.4 0.1 0.7 10.1 0.1 2.2 1 1 1 2 2 2 0 SpoU rRNA Methylase family Aldose_epim PF01263.20 EMR71711.1 - 4.9e-48 164.0 0.3 6.6e-48 163.6 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1115 PF06544.12 EMR71712.1 - 3.2e-12 46.8 0.0 6.4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Lactamase_B PF00753.27 EMR71714.1 - 5.7e-06 26.5 2.3 5.7e-05 23.2 2.3 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMR71714.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pectate_lyase PF03211.13 EMR71715.1 - 3e-66 222.9 5.6 3.9e-66 222.5 5.6 1.1 1 0 0 1 1 1 1 Pectate lyase P21-Arc PF04062.14 EMR71716.1 - 8.4e-74 247.3 0.0 9.6e-74 247.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ATP-synt_ab PF00006.25 EMR71717.1 - 2e-66 223.7 0.0 2.9e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EMR71717.1 - 1.1e-13 51.4 0.6 1.9e-13 50.7 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Gcd10p PF04189.13 EMR71718.1 - 1.3e-106 356.1 0.0 1.7e-106 355.7 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family SelP_N PF04592.14 EMR71718.1 - 0.34 10.3 14.2 0.62 9.4 14.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 EMR71718.1 - 0.85 8.8 7.3 1.3 8.2 7.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2796 PF10986.8 EMR71718.1 - 1.3 9.0 14.5 2.2 8.2 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) ADH_zinc_N PF00107.26 EMR71719.1 - 2.7e-17 62.9 0.0 5.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR71719.1 - 3.5e-16 59.0 0.5 7.4e-15 54.8 0.3 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EMR71719.1 - 0.00082 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMR71719.1 - 0.031 15.3 0.0 0.06 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMR71719.1 - 0.13 11.5 0.2 0.44 9.8 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain tRNA-synt_1g PF09334.11 EMR71720.1 - 5.6e-142 473.1 0.2 2e-140 468.0 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EMR71720.1 - 1.6e-07 30.0 0.1 0.0033 15.8 0.0 3.8 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMR71720.1 - 0.0021 18.1 0.0 0.0054 16.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF416 PF04222.12 EMR71720.1 - 0.034 13.6 0.6 0.56 9.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Laminin_EGF PF00053.24 EMR71720.1 - 0.11 12.6 1.8 0.22 11.7 1.8 1.4 1 0 0 1 1 1 0 Laminin EGF domain Sugar_tr PF00083.24 EMR71721.1 - 1.6e-91 307.5 19.5 2e-91 307.1 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR71721.1 - 1.4e-30 106.4 29.9 1.4e-20 73.5 5.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR71721.1 - 0.0019 16.7 1.7 0.0019 16.7 1.7 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMR71721.1 - 0.61 8.3 22.4 0.17 10.1 1.7 3.4 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family CENP-K PF11802.8 EMR71722.1 - 0.0014 18.3 1.9 0.0019 17.9 1.2 1.5 1 1 0 1 1 1 1 Centromere-associated protein K Spc7 PF08317.11 EMR71722.1 - 0.0088 15.0 1.9 0.0088 15.0 1.9 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF745 PF05335.13 EMR71722.1 - 0.011 15.4 1.3 0.024 14.4 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MscS_porin PF12795.7 EMR71722.1 - 0.017 14.7 2.0 0.017 14.7 2.0 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain CC2-LZ PF16516.5 EMR71722.1 - 0.043 14.2 2.3 0.043 14.2 2.3 2.0 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator UNC-79 PF14776.6 EMR71722.1 - 0.044 12.6 0.5 0.054 12.2 0.5 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Prefoldin_2 PF01920.20 EMR71722.1 - 0.05 13.6 7.8 0.074 13.0 2.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit SKA1 PF07160.12 EMR71722.1 - 0.053 13.4 1.9 2.1 8.1 1.0 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 P4Ha_N PF08336.11 EMR71722.1 - 0.054 13.5 1.4 0.35 10.9 0.2 2.5 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4094 PF13334.6 EMR71722.1 - 0.074 13.5 1.8 0.18 12.3 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF1664 PF07889.12 EMR71722.1 - 0.3 11.1 3.5 3.4 7.7 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FliD_N PF02465.18 EMR71722.1 - 0.61 10.8 5.3 0.31 11.7 0.5 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TACC_C PF05010.14 EMR71722.1 - 1.2 8.9 8.9 0.16 11.8 3.4 2.1 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SseC PF04888.12 EMR71722.1 - 1.6 8.2 5.4 1.3 8.6 1.1 2.4 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family Fib_alpha PF08702.10 EMR71722.1 - 2 8.6 6.4 0.38 10.9 1.4 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 EMR71722.1 - 3.2 7.9 9.9 11 6.1 0.3 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TBCA PF02970.16 EMR71722.1 - 5 7.5 8.8 0.93 9.9 2.2 2.5 3 0 0 3 3 2 0 Tubulin binding cofactor A FlaC_arch PF05377.11 EMR71722.1 - 6.6 7.2 6.1 1.7 9.1 1.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DNA_pol3_chi PF04364.13 EMR71723.1 - 0.083 13.1 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC DUF604 PF04646.12 EMR71724.1 - 8.7e-11 41.7 0.1 3.6e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.16 EMR71724.1 - 3.4e-07 30.0 0.0 6.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Fringe-like ADH_zinc_N PF00107.26 EMR71725.1 - 0.00061 19.8 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR71725.1 - 0.0056 17.7 0.0 0.06 14.4 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF3218 PF11508.8 EMR71725.1 - 0.059 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) adh_short PF00106.25 EMR71725.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 EMR71725.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AtuA PF07287.11 EMR71726.1 - 7.2e-130 432.8 0.0 8.7e-130 432.5 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA ADH_zinc_N PF00107.26 EMR71727.1 - 2e-24 86.0 0.0 3.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR71727.1 - 1.9e-19 69.6 3.9 3.3e-19 68.8 3.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 EMR71727.1 - 0.00022 20.7 0.1 0.00036 19.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMR71727.1 - 0.00089 18.6 0.2 0.0013 18.0 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EMR71727.1 - 0.016 14.6 1.3 0.03 13.7 1.3 1.4 1 0 0 1 1 1 0 ThiF family Methyltransf_25 PF13649.6 EMR71727.1 - 0.019 15.6 0.1 0.043 14.5 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EMR71727.1 - 0.045 13.0 0.1 0.065 12.5 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EMR71727.1 - 0.049 13.4 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PglD_N PF17836.1 EMR71727.1 - 0.053 14.2 0.1 0.2 12.3 0.0 2.0 2 0 0 2 2 2 0 PglD N-terminal domain UbiD PF01977.16 EMR71728.1 - 1.3e-97 327.3 0.0 2.1e-97 326.6 0.0 1.3 1 1 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Aldedh PF00171.22 EMR71729.1 - 3.1e-153 510.6 0.0 3.8e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BRO1 PF03097.18 EMR71730.1 - 5.3e-120 400.8 0.0 8.6e-120 400.1 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EMR71730.1 - 2.2e-82 276.7 2.3 2.2e-82 276.7 2.3 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV PAT1 PF09770.9 EMR71730.1 - 6.2 5.0 23.3 11 4.2 23.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cep57_CLD_2 PF14197.6 EMR71730.1 - 6.8 6.9 19.6 0.087 12.9 2.8 3.9 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 Flavoprotein PF02441.19 EMR71731.1 - 1.1e-23 83.8 0.1 1.4e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein HMGL-like PF00682.19 EMR71732.1 - 5.1e-43 147.5 0.1 4.6e-42 144.4 0.1 1.9 1 1 0 1 1 1 1 HMGL-like NAD_binding_4 PF07993.12 EMR71733.1 - 9.8e-34 116.7 0.0 1.4e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EMR71733.1 - 7.1e-12 45.3 0.0 1.7e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR71733.1 - 1.1e-05 25.6 0.1 3e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 EMR71733.1 - 0.00013 20.7 0.0 0.00023 19.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.10 EMR71733.1 - 0.0024 17.8 0.0 0.0086 16.0 0.0 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EMR71733.1 - 0.0069 15.4 0.0 0.044 12.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMR71733.1 - 0.033 13.3 0.1 0.77 8.8 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EMR71733.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1077 PF06417.12 EMR71734.1 - 1.2e-50 170.4 4.5 1.6e-50 170.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 EMR71735.1 - 1.8e-99 333.7 5.9 5e-59 200.3 0.2 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EMR71735.1 - 6e-32 110.9 6.7 3.2e-31 108.6 0.2 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMR71735.1 - 3.1e-15 56.3 6.3 1.3e-05 25.5 0.1 4.3 3 1 1 4 4 4 4 HEAT repeats HEAT PF02985.22 EMR71735.1 - 2.7e-10 39.6 3.2 0.0014 18.8 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat CLASP_N PF12348.8 EMR71735.1 - 0.0015 18.2 0.4 0.63 9.6 0.1 3.1 2 1 0 2 2 2 2 CLASP N terminal Atx10homo_assoc PF09759.9 EMR71735.1 - 0.0015 18.5 0.8 28 4.8 0.0 4.3 5 1 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EMR71735.1 - 0.0043 17.5 5.3 10 6.7 0.1 5.6 5 1 1 6 6 6 1 HEAT-like repeat RTP1_C1 PF10363.9 EMR71735.1 - 0.071 13.3 0.2 4.1 7.6 0.0 3.0 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EMR71735.1 - 0.082 13.0 0.1 3.7 7.7 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Semialdhyde_dhC PF02774.18 EMR71736.1 - 1.1e-37 130.0 0.0 1.3e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EMR71736.1 - 0.00018 21.9 0.0 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TMEM154 PF15102.6 EMR71737.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 TMEM154 protein family TNFR_16_TM PF18422.1 EMR71737.1 - 0.2 11.7 0.3 0.34 10.9 0.3 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DLIC PF05783.11 EMR71737.1 - 0.27 10.0 4.7 0.37 9.6 4.7 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF998 PF06197.13 EMR71737.1 - 0.28 10.8 2.4 0.34 10.5 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF998) FSA_C PF10479.9 EMR71737.1 - 6.7 4.7 10.7 8 4.5 10.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Peptidase_M43 PF05572.13 EMR71738.1 - 1.8e-09 37.7 0.0 3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EMR71738.1 - 3.5e-05 24.3 0.1 9.7e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EMR71738.1 - 0.0003 21.0 0.1 0.00052 20.2 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Gpr1_Fun34_YaaH PF01184.19 EMR71740.1 - 1.5e-29 103.1 0.3 1.9e-29 102.7 0.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family IBR PF01485.21 EMR71741.1 - 7.7e-13 48.5 35.3 2.2e-09 37.4 9.0 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EMR71741.1 - 0.006 16.6 3.0 0.006 16.6 3.0 3.5 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 EMR71741.1 - 0.0099 16.2 3.9 0.0099 16.2 3.9 3.8 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMR71741.1 - 0.014 15.3 0.5 0.014 15.3 0.5 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMR71741.1 - 0.018 14.8 1.2 0.018 14.8 1.2 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EMR71741.1 - 0.023 14.9 2.9 0.023 14.9 2.9 3.9 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF2732 PF10809.8 EMR71741.1 - 0.074 12.9 3.0 0.15 12.0 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) CorA PF01544.18 EMR71741.1 - 0.1 11.9 0.8 0.15 11.3 0.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Syntaxin PF00804.25 EMR71741.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Syntaxin Pal1 PF08316.11 EMR71742.1 - 5.4e-10 40.2 0.1 1.1e-09 39.2 0.1 1.8 1 1 0 1 1 1 1 Pal1 cell morphology protein Bromodomain PF00439.25 EMR71743.1 - 1.5e-28 98.6 0.0 7.4e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 Bromodomain SDA1 PF05285.12 EMR71743.1 - 0.071 12.5 35.5 0.12 11.8 35.5 1.4 1 0 0 1 1 1 0 SDA1 EF1G PF00647.19 EMR71743.1 - 0.19 11.8 0.3 0.49 10.5 0.1 1.8 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain BUD22 PF09073.10 EMR71743.1 - 0.39 10.0 32.1 0.72 9.1 32.1 1.5 1 0 0 1 1 1 0 BUD22 DUF2201_N PF13203.6 EMR71743.1 - 2.5 7.6 6.4 0.32 10.5 0.9 2.1 1 1 1 2 2 2 0 Putative metallopeptidase domain Aldedh PF00171.22 EMR71744.1 - 2.4e-141 471.4 0.0 2.9e-141 471.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2199 PF09965.9 EMR71744.1 - 0.044 13.8 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) CKS PF01111.19 EMR71745.1 - 8e-33 112.5 0.8 1.1e-32 112.0 0.8 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit G-patch PF01585.23 EMR71746.1 - 0.017 15.0 2.4 0.029 14.3 0.3 2.6 2 1 0 2 2 2 0 G-patch domain SRP-alpha_N PF04086.13 EMR71746.1 - 0.096 12.6 14.7 0.16 11.8 14.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hid1 PF12722.7 EMR71746.1 - 4 5.4 7.0 4.5 5.3 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HVSL PF09749.9 EMR71747.1 - 1.1e-57 195.3 0.0 1.4e-44 152.4 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein MBOAT PF03062.19 EMR71748.1 - 3.2e-41 141.8 16.3 3.2e-41 141.8 16.3 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Apolipoprotein PF01442.18 EMR71748.1 - 0.23 11.3 0.1 0.35 10.7 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain WD40 PF00400.32 EMR71749.1 - 1.9e-14 53.8 5.4 5.8e-05 23.8 0.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR71749.1 - 2.7e-09 37.2 2.0 0.0032 17.7 0.0 5.1 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMR71749.1 - 4.7e-05 23.3 0.3 0.086 12.7 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 EMR71749.1 - 0.0014 18.3 1.7 0.014 15.0 0.1 2.7 2 1 0 2 2 2 1 PQQ-like domain Thg1C PF14413.6 EMR71750.1 - 2.5e-22 79.3 0.3 2.9e-22 79.1 0.3 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain Baculo_PEP_C PF04513.12 EMR71752.1 - 0.069 13.2 1.4 0.33 11.0 0.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_Rpb1_1 PF04997.12 EMR71753.1 - 2.4e-107 358.9 0.1 4e-107 358.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EMR71753.1 - 2e-99 332.3 0.0 3.3e-99 331.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMR71753.1 - 2.6e-77 258.7 0.0 4.7e-77 257.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EMR71753.1 - 1.8e-54 184.5 0.5 3.2e-54 183.7 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EMR71753.1 - 3.1e-46 157.2 0.0 1.1e-45 155.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EMR71753.1 - 1.8e-43 147.8 6.9 7.6e-43 145.8 6.5 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EMR71753.1 - 2.2e-35 120.9 0.0 4.9e-35 119.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 GXWXG PF14231.6 EMR71753.1 - 0.035 14.2 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 GXWXG protein CPSF_A PF03178.15 EMR71756.1 - 2.5e-84 283.3 0.0 3.1e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region Spt20 PF12090.8 EMR71756.1 - 0.1 12.2 7.0 0.19 11.3 7.0 1.4 1 0 0 1 1 1 0 Spt20 family PBP1_TM PF14812.6 EMR71757.1 - 0.15 12.5 1.3 0.39 11.1 1.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gln-synt_C PF00120.24 EMR71759.1 - 6.3e-84 281.9 0.0 7.6e-84 281.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EMR71759.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain MFS_1 PF07690.16 EMR71760.1 - 2e-34 119.0 19.6 2.3e-34 118.9 19.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMR71760.1 - 2.6e-05 23.7 2.6 3.8e-05 23.2 2.6 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB NR_Repeat PF14046.6 EMR71760.1 - 0.22 11.7 0.1 9.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Nuclear receptor repeat DUF1932 PF09130.11 EMR71761.1 - 2.4e-27 94.7 0.3 6.1e-27 93.4 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 EMR71761.1 - 5.3e-07 30.1 0.2 1.3e-06 28.8 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EMR71761.1 - 0.00011 22.4 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Serglycin PF04360.12 EMR71761.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Serglycin 3HCDH_N PF02737.18 EMR71761.1 - 0.048 13.6 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4719 PF15843.5 EMR71761.1 - 0.13 12.4 0.5 0.22 11.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) 2-Hacid_dh_C PF02826.19 EMR71761.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AF-4 PF05110.13 EMR71761.1 - 9.3 4.2 5.8 12 3.8 5.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein F-box-like PF12937.7 EMR71762.1 - 0.0059 16.5 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like DAGAT PF03982.13 EMR71763.1 - 5e-94 314.5 0.0 6.5e-94 314.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MRC1 PF09444.10 EMR71763.1 - 0.054 14.0 3.5 0.087 13.3 3.5 1.2 1 0 0 1 1 1 0 MRC1-like domain GET2 PF08690.10 EMR71763.1 - 0.72 9.5 1.8 1.1 8.9 1.8 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 PI-PLC-X PF00388.19 EMR71764.1 - 5.1e-10 39.1 0.0 7.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SnoaL_4 PF13577.6 EMR71765.1 - 5.5e-08 33.0 0.1 6.9e-08 32.7 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain Aminotran_5 PF00266.19 EMR71766.1 - 2.4e-20 72.8 0.0 3.3e-08 32.9 0.0 4.3 2 1 0 2 2 2 2 Aminotransferase class-V SUIM_assoc PF16619.5 EMR71766.1 - 0.046 13.8 0.9 0.046 13.8 0.9 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SWI-SNF_Ssr4 PF08549.10 EMR71767.1 - 9.1e-131 437.8 15.4 1.2e-130 437.4 15.4 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) PNISR PF15996.5 EMR71767.1 - 8.4 6.6 12.0 0.041 14.2 1.6 2.1 2 1 0 2 2 2 0 Arginine/serine-rich protein PNISR 6PGD PF00393.19 EMR71769.1 - 1.6e-126 421.6 0.0 2e-126 421.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EMR71769.1 - 1.3e-50 171.7 0.0 2e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMR71769.1 - 0.027 14.7 0.1 0.098 12.9 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EMR71769.1 - 0.062 13.9 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EMR71769.1 - 0.16 11.3 0.0 0.4 10.0 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.22 EMR71770.1 - 3.5e-16 58.8 0.0 5.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pectate_lyase PF03211.13 EMR71771.1 - 7e-17 61.6 0.3 7.6e-17 61.5 0.3 1.0 1 0 0 1 1 1 1 Pectate lyase RRM_1 PF00076.22 EMR71772.1 - 3.8e-15 55.5 0.0 6.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRP PF06011.12 EMR71773.1 - 1.7e-135 452.1 15.8 2.1e-135 451.8 15.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EMR71773.1 - 8.9e-40 136.3 2.9 8.9e-40 136.3 2.9 1.7 1 1 1 2 2 2 1 ML-like domain TPT PF03151.16 EMR71774.1 - 3.9e-08 33.0 0.2 4.8e-08 32.7 0.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EMR71774.1 - 0.014 15.6 5.4 0.016 15.4 5.4 1.2 1 0 0 1 1 1 0 EamA-like transporter family zf-C2H2 PF00096.26 EMR71775.1 - 4.3e-08 33.2 24.5 0.00032 21.0 0.6 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMR71775.1 - 0.0011 19.6 0.6 0.0011 19.6 0.6 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EMR71775.1 - 0.035 14.0 0.2 0.18 11.7 0.2 2.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EMR71775.1 - 0.061 13.4 0.7 0.061 13.4 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMR71775.1 - 2.3 8.6 12.1 11 6.4 0.8 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EMR71775.1 - 2.4 8.6 9.6 0.19 12.1 2.2 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF202 PF02656.15 EMR71776.1 - 6.9e-05 23.2 3.6 6.9e-05 23.2 3.6 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF1376 PF07120.11 EMR71776.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) Serglycin PF04360.12 EMR71777.1 - 9.1 6.2 6.5 19 5.2 6.5 1.6 1 0 0 1 1 1 0 Serglycin Use1 PF09753.9 EMR71778.1 - 0.00042 20.1 0.0 0.00043 20.1 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sod_Fe_C PF02777.18 EMR71779.1 - 7.8e-39 132.0 0.1 1.4e-38 131.1 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMR71779.1 - 1.9e-32 111.6 2.2 3.1e-32 110.9 2.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.12 EMR71780.1 - 4.6e-65 220.0 3.3 4.8e-65 219.9 2.1 1.7 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EMR71780.1 - 1.4e-14 53.7 1.0 4.6e-14 52.0 1.0 2.0 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 EMR71780.1 - 8.7e-13 48.5 10.3 8.7e-13 48.5 10.3 3.7 3 1 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 EMR71780.1 - 1.1e-05 25.5 0.6 1.1e-05 25.5 0.6 3.8 4 1 0 4 4 4 1 G-patch domain DUF4192 PF13830.6 EMR71780.1 - 0.014 15.5 0.4 0.014 15.5 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Sld5 PF05916.11 EMR71781.1 - 9.6e-21 74.3 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Apc15p PF05841.11 EMR71782.1 - 1.6e-32 112.9 10.7 1.6e-32 112.9 10.7 1.7 2 0 0 2 2 2 1 Apc15p protein TFIIA PF03153.13 EMR71782.1 - 0.0049 16.9 21.1 0.0049 16.9 21.1 2.1 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit Auxin_canalis PF05703.11 EMR71782.1 - 0.006 16.5 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Auxin canalisation Suv3_C_1 PF18147.1 EMR71784.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 IBN_N PF03810.19 EMR71786.1 - 9.7e-12 44.6 0.0 2.9e-09 36.7 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 EMR71786.1 - 2.5e-06 26.6 0.1 1.7e-05 23.9 0.0 2.0 1 1 0 2 2 2 1 Cse1 Xpo1 PF08389.12 EMR71786.1 - 0.013 15.6 1.1 0.1 12.7 0.0 3.0 3 0 0 3 3 3 0 Exportin 1-like protein CAS_CSE1 PF03378.15 EMR71786.1 - 0.019 13.5 0.0 0.061 11.8 0.0 1.8 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Cnd1 PF12717.7 EMR71786.1 - 0.048 13.7 0.2 0.27 11.3 0.2 2.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMR71786.1 - 0.067 13.6 3.7 5.1 7.6 0.4 3.4 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 EMR71786.1 - 0.18 12.2 0.3 1.4 9.4 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat IMS PF00817.20 EMR71787.1 - 2.3e-32 112.1 0.0 3.4e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 EMR71787.1 - 0.00044 20.4 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Peptidase_S8 PF00082.22 EMR71788.1 - 1.9e-29 102.9 13.0 5.7e-29 101.3 12.9 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMR71788.1 - 1.2e-09 38.7 0.1 8e-09 36.1 0.1 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 Amidohydro_1 PF01979.20 EMR71789.1 - 2.2e-34 119.3 0.1 2.8e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR71789.1 - 3.8e-09 36.5 0.6 6.3e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family PAM2 PF07145.15 EMR71790.1 - 0.0044 16.6 10.6 0.48 10.2 0.1 3.8 3 0 0 3 3 3 3 Ataxin-2 C-terminal region Cerato-platanin PF07249.12 EMR71791.1 - 6.7e-54 181.1 4.3 7.6e-54 180.9 4.3 1.0 1 0 0 1 1 1 1 Cerato-platanin Aldedh PF00171.22 EMR71792.1 - 2.8e-110 369.0 0.0 3.5e-110 368.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoLip_ATPase_C PF16212.5 EMR71793.1 - 9.1e-79 264.7 23.9 9.1e-79 264.7 23.9 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMR71793.1 - 7.8e-20 70.3 2.8 1.1e-19 69.9 1.5 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EMR71793.1 - 2.9e-13 49.7 0.0 1.2e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMR71793.1 - 1.1e-11 45.4 7.5 2.7e-08 34.4 3.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EMR71793.1 - 0.0086 15.6 0.0 0.0086 15.6 0.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EMR71793.1 - 0.028 14.2 1.5 0.07 12.8 1.5 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_tran_WbsX PF14307.6 EMR71794.1 - 2.1e-11 43.9 0.5 2.8e-11 43.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase WbsX AKAP2_C PF15304.6 EMR71794.1 - 0.0016 17.8 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus SBF2 PF12335.8 EMR71794.1 - 0.15 11.6 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Myotubularin protein XPA_C PF05181.12 EMR71795.1 - 1.2e-25 89.2 1.7 2.5e-25 88.2 1.7 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EMR71795.1 - 0.0045 17.0 4.8 0.0045 17.0 4.8 2.0 3 0 0 3 3 3 1 XPA protein N-terminal GRP PF07172.11 EMR71795.1 - 0.11 13.2 7.1 0.23 12.1 7.1 1.5 1 0 0 1 1 1 0 Glycine rich protein family C1_1 PF00130.22 EMR71795.1 - 0.73 9.8 6.3 1.3 9.0 3.8 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YhfH PF14149.6 EMR71795.1 - 1.1 9.3 9.6 1.1 9.3 0.2 2.8 3 0 0 3 3 3 0 YhfH-like protein DZR PF12773.7 EMR71795.1 - 2.6 8.2 5.9 23 5.1 3.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EMR71795.1 - 7.3 6.8 8.3 9.7 6.4 0.3 2.8 2 1 1 3 3 3 0 Zinc ribbon domain p450 PF00067.22 EMR71796.1 - 4.2e-79 266.4 0.0 5.8e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EMR71796.1 - 1.4e-28 100.0 0.0 2.3e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EMR71796.1 - 4e-26 91.9 0.0 7.4e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EMR71796.1 - 3.3e-11 43.8 0.0 8.8e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EMR71796.1 - 0.039 14.2 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain FAD_binding_6 PF00970.24 EMR71796.1 - 0.099 13.0 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain FMN_red PF03358.15 EMR71796.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.7 1 1 0 1 1 1 0 NADPH-dependent FMN reductase AAA PF00004.29 EMR71797.1 - 4.1e-05 24.0 0.0 0.00013 22.4 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RdRP PF05183.12 EMR71798.1 - 3.8e-123 412.2 0.0 5e-120 401.9 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase Pho88 PF10032.9 EMR71799.1 - 4.9e-82 273.6 0.0 5.5e-82 273.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4512 PF14975.6 EMR71799.1 - 0.054 14.3 0.1 0.2 12.4 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) DUF5489 PF17592.2 EMR71799.1 - 0.077 13.5 0.9 0.18 12.4 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5489) Rab5ip PF07019.12 EMR71799.1 - 0.12 12.9 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Aminotran_5 PF00266.19 EMR71800.1 - 5.4e-23 81.5 0.0 2.3e-22 79.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMR71800.1 - 0.0079 15.4 0.0 0.019 14.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_1 PF00561.20 EMR71801.1 - 1.1e-10 41.6 0.0 1.9e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR71801.1 - 4.7e-10 40.4 0.5 8.2e-10 39.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR71801.1 - 4.6e-05 22.8 0.0 0.00011 21.5 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EthD PF07110.11 EMR71801.1 - 0.0015 19.7 0.0 0.043 15.0 0.0 2.6 2 0 0 2 2 2 1 EthD domain Esterase PF00756.20 EMR71801.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 Putative esterase ABM PF03992.16 EMR71801.1 - 0.13 12.4 0.1 0.39 10.9 0.1 1.8 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF1479 PF07350.12 EMR71804.1 - 3.9e-148 493.7 0.0 4.9e-148 493.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Dehydrin PF00257.19 EMR71804.1 - 1.1 9.7 7.4 1.3 9.6 6.2 1.6 1 1 0 1 1 1 0 Dehydrin SnoaL_2 PF12680.7 EMR71806.1 - 0.12 13.0 0.0 8.7 7.0 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain Shikimate_dh_N PF08501.11 EMR71807.1 - 2.4e-22 79.0 0.0 4.3e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EMR71807.1 - 2.4e-06 27.2 0.4 5.3e-06 26.1 0.4 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EMR71807.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cation_ATPase_C PF00689.21 EMR71808.1 - 3.6e-47 160.4 10.7 3.6e-47 160.4 10.7 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EMR71808.1 - 3.4e-34 118.0 0.8 3.4e-34 118.0 0.8 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EMR71808.1 - 1.4e-21 76.3 0.0 2.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMR71808.1 - 1.3e-20 74.6 2.5 3.3e-20 73.3 2.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMR71808.1 - 6.9e-12 44.9 0.1 1.4e-10 40.7 0.0 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMR71808.1 - 0.0013 18.5 0.1 0.011 15.4 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3429 PF11911.8 EMR71808.1 - 0.59 10.4 5.4 0.11 12.8 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) Sugar_tr PF00083.24 EMR71809.1 - 3.4e-98 329.4 18.4 3.4e-92 309.7 11.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter RhodobacterPufX PF11511.8 EMR71809.1 - 0.41 10.3 0.1 0.41 10.3 0.1 2.6 2 0 0 2 2 2 0 Intrinsic membrane protein PufX adh_short PF00106.25 EMR71810.1 - 3.8e-43 147.2 0.4 4.9e-43 146.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71810.1 - 5.1e-31 108.0 0.2 6.6e-31 107.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71810.1 - 1.8e-06 28.0 0.2 2.5e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR71810.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 EMR71810.1 - 0.062 12.7 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_43 PF04616.14 EMR71811.1 - 1e-06 28.3 2.0 0.0016 17.8 1.9 3.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.16 EMR71811.1 - 0.058 12.2 0.0 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Levansucrase/Invertase Thioesterase PF00975.20 EMR71812.1 - 2e-29 103.3 0.0 3.9e-29 102.4 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain AMP-binding PF00501.28 EMR71812.1 - 2e-24 86.0 0.0 3.7e-24 85.1 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EMR71812.1 - 2.8e-08 34.0 0.1 7.6e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 EMR71812.1 - 0.004 17.8 0.2 0.0081 16.8 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR71812.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FCH PF00611.23 EMR71813.1 - 5.4e-24 84.3 3.2 5.9e-24 84.2 0.0 2.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EMR71813.1 - 7.3e-23 80.2 0.3 9.5e-13 47.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EMR71813.1 - 1.1e-15 56.9 0.1 7.6e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 EMR71813.1 - 2e-08 34.0 0.9 3.4e-08 33.3 0.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 EMR71813.1 - 5.1e-05 23.5 0.1 0.031 14.5 0.0 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_2 PF07653.17 EMR71813.1 - 0.00053 19.6 0.1 0.67 9.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 EMR71813.1 - 0.056 13.5 0.4 2.3 8.4 0.0 3.3 4 0 0 4 4 4 0 SH3 domain zf-C4H2 PF10146.9 EMR71813.1 - 0.97 9.7 8.6 6.5 7.0 3.6 2.9 2 1 1 3 3 3 0 Zinc finger-containing protein CENP-Q PF13094.6 EMR71813.1 - 5.3 7.2 9.1 6.8 6.9 0.3 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FeS PF04060.13 EMR71813.1 - 5.4 6.8 4.8 13 5.5 0.6 2.5 2 0 0 2 2 2 0 Putative Fe-S cluster Epiglycanin_TR PF05647.11 EMR71813.1 - 7 6.7 11.7 0.35 10.8 6.0 1.8 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Glyco_hydro_72 PF03198.14 EMR71814.1 - 9e-126 419.4 1.7 1.1e-125 419.0 1.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EMR71814.1 - 2.3e-05 24.0 0.1 0.00057 19.4 0.1 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DEAD PF00270.29 EMR71816.1 - 1.2e-33 116.4 0.4 1.2e-32 113.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR71816.1 - 9.5e-28 96.8 0.2 3.9e-27 94.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR71816.1 - 4.8e-05 23.4 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMR71816.1 - 5.6e-05 22.9 0.0 9.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR71816.1 - 0.0026 18.1 0.0 0.049 14.0 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 EMR71816.1 - 0.011 16.0 1.0 0.75 10.1 0.7 2.9 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.6 EMR71816.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TniB PF05621.11 EMR71816.1 - 0.11 11.8 0.1 0.32 10.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial TniB protein DUF2075 PF09848.9 EMR71816.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IMPa_N_2 PF18650.1 EMR71816.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain SIR2 PF02146.17 EMR71817.1 - 3.7e-31 108.4 0.0 3.6e-11 43.3 0.0 3.1 3 0 0 3 3 3 3 Sir2 family TPP_enzyme_M PF00205.22 EMR71817.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain DNA_ligase_OB PF03120.16 EMR71817.1 - 0.031 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain But2 PF09792.9 EMR71818.1 - 0.0002 21.8 0.0 0.00054 20.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain S4 PF01479.25 EMR71819.1 - 1.2e-11 44.1 0.0 3e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EMR71819.1 - 1.3e-11 45.2 0.5 2.3e-11 44.5 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain SNF2_N PF00176.23 EMR71820.1 - 6.8e-47 159.9 0.0 1.1e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EMR71820.1 - 2.8e-24 85.0 0.9 9.2e-24 83.3 0.9 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EMR71820.1 - 3.9e-20 72.2 0.0 2.4e-19 69.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EMR71820.1 - 5.8e-07 29.0 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EMR71820.1 - 1.8e-05 24.8 0.0 9e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 EMR71820.1 - 0.06 12.2 0.2 1.2 8.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 DUF2462 PF09495.10 EMR71821.1 - 1.1e-18 67.8 8.5 1.1e-18 67.8 8.5 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) RNase_H PF00075.24 EMR71822.1 - 3.3e-20 72.7 0.2 9.3e-20 71.3 0.2 1.7 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EMR71822.1 - 0.0011 18.8 0.1 0.67 9.8 0.0 3.3 2 1 0 2 2 2 1 Reverse transcriptase-like CPL PF08144.11 EMR71822.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 CPL (NUC119) domain TFIIA PF03153.13 EMR71823.1 - 0.32 11.0 16.2 0.52 10.2 16.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CFEM PF05730.11 EMR71825.1 - 0.00019 21.5 3.2 0.00037 20.5 3.2 1.5 1 1 0 1 1 1 1 CFEM domain PsaL PF02605.15 EMR71826.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI CoA_transf_3 PF02515.17 EMR71827.1 - 1.1e-31 110.3 0.6 2.6e-31 109.1 0.6 1.6 1 1 0 1 1 1 1 CoA-transferase family III Sugar_tr PF00083.24 EMR71828.1 - 5.6e-107 358.4 23.2 6.6e-107 358.2 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR71828.1 - 5.6e-16 58.4 43.0 8.3e-15 54.6 32.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR71828.1 - 3.9e-07 28.9 10.1 3.9e-05 22.3 4.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3566 PF12089.8 EMR71828.1 - 0.54 10.6 5.2 17 5.8 0.1 3.9 4 0 0 4 4 4 0 Transmembrane domain of unknown function (DUF3566) 3HCDH_N PF02737.18 EMR71829.1 - 3e-43 147.8 0.0 4.2e-42 144.1 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EMR71829.1 - 1.4e-09 38.5 0.0 2.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 EMR71829.1 - 0.00026 20.4 0.1 0.0024 17.2 0.0 2.3 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EMR71829.1 - 0.0091 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 EMR71829.1 - 0.033 14.6 0.0 0.53 10.8 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding adh_short_C2 PF13561.6 EMR71829.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Transketolase_N PF00456.21 EMR71830.1 - 1.6e-107 359.4 0.0 2.3e-107 358.8 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EMR71830.1 - 3.1e-32 111.7 0.0 6.6e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMR71830.1 - 1.4e-11 44.4 0.0 5.8e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EMR71830.1 - 1.8e-07 30.7 0.1 1.4e-06 27.8 0.2 2.3 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EMR71830.1 - 0.00033 20.5 1.2 0.0017 18.2 1.2 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EMR71830.1 - 0.08 11.9 0.0 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 Dehydrogenase E1 component adh_short_C2 PF13561.6 EMR71831.1 - 3.6e-47 160.9 0.0 4.5e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR71831.1 - 1.2e-41 142.3 0.1 1.6e-41 141.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR71831.1 - 1.1e-13 51.6 0.1 2.7e-13 50.2 0.1 1.6 1 1 0 1 1 1 1 KR domain K-cyclin_vir_C PF09080.10 EMR71831.1 - 0.12 12.8 1.0 1.1 9.7 0.7 2.3 2 0 0 2 2 2 0 K cyclin, C terminal ADH_N PF08240.12 EMR71832.1 - 6.7e-21 74.2 0.1 1.3e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMR71832.1 - 1.9e-11 44.1 0.1 4.2e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMR71832.1 - 8.7e-08 31.9 0.4 5.3e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ThiF PF00899.21 EMR71832.1 - 0.13 11.6 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 EMR71832.1 - 0.17 11.1 2.2 0.14 11.4 0.5 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMR71833.1 - 2.3e-20 72.5 0.0 2.8e-16 59.1 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR71833.1 - 8.4e-16 58.1 0.0 3.2e-14 52.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR71833.1 - 9.9e-11 41.4 0.0 2.5e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR71833.1 - 1.5e-10 41.1 0.0 4.7e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EMR71833.1 - 3.4e-08 33.0 0.3 6.5e-06 25.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EMR71833.1 - 2.7e-06 27.2 0.0 0.00048 19.8 0.0 3.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMR71833.1 - 0.0019 18.2 0.5 0.13 12.2 0.0 3.5 4 1 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 EMR71833.1 - 0.08 12.2 0.1 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 EMR71833.1 - 0.11 11.5 2.3 0.77 8.7 2.3 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 EMR71834.1 - 1.4e-31 109.8 0.0 2.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EMR71834.1 - 2.5e-15 56.9 0.0 5.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EMR71834.1 - 0.00029 21.0 0.0 0.00074 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SGL PF08450.12 EMR71834.1 - 0.002 17.7 0.0 0.071 12.7 0.0 2.7 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_b PF00058.17 EMR71834.1 - 0.0028 18.1 1.1 24 5.5 0.0 5.5 5 1 0 5 5 5 1 Low-density lipoprotein receptor repeat class B NAD_Gly3P_dh_N PF01210.23 EMR71834.1 - 0.0037 17.2 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EMR71834.1 - 0.043 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 EMR71836.1 - 1.1e-11 44.6 0.0 1.6e-08 34.3 0.0 2.3 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71836.1 - 1.5e-11 44.4 0.0 7.5e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71836.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 1 0 1 1 1 0 KR domain p450 PF00067.22 EMR71837.1 - 3.3e-57 194.3 0.0 4e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FTA2 PF13095.6 EMR71838.1 - 4.4e-61 206.2 0.0 4.9e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 PNPase_C PF12111.8 EMR71839.1 - 0.0037 16.7 2.7 0.0037 16.7 2.7 2.6 2 0 0 2 2 2 1 Polyribonucleotide phosphorylase C terminal Endomucin PF07010.12 EMR71839.1 - 0.074 13.0 19.3 0.16 11.9 19.3 1.6 1 0 0 1 1 1 0 Endomucin Glyco_transf_22 PF03901.17 EMR71840.1 - 1.9e-85 287.7 17.1 2.2e-85 287.4 17.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 EMR71841.1 - 1.8e-43 147.9 0.0 3.8e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region HET PF06985.11 EMR71842.1 - 1.6e-28 99.9 0.0 2.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 EMR71843.1 - 7.4e-05 21.9 1.7 0.00013 21.1 1.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Dicty_CAR PF05462.11 EMR71844.1 - 2.1e-12 46.8 7.8 2.1e-12 46.8 7.8 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 EMR71844.1 - 3.8e-08 33.0 6.4 5.7e-08 32.4 6.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 EMR71844.1 - 1.1e-05 25.3 12.4 2.3e-05 24.3 12.4 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 EMR71844.1 - 0.042 13.2 6.6 0.068 12.5 6.6 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Arc_PepC_II PF06847.11 EMR71844.1 - 2.4 8.7 4.5 6.6 7.3 0.1 2.6 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II zf-LITAF-like PF10601.9 EMR71844.1 - 2.5 8.4 3.9 4.2 7.7 0.0 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Ras PF00071.22 EMR71845.1 - 4.4e-57 192.2 0.0 5.1e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR71845.1 - 9.7e-32 109.7 0.0 1.4e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMR71845.1 - 2.1e-13 50.1 0.0 2.5e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMR71845.1 - 2.6e-08 33.9 0.0 4.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EMR71845.1 - 1.9e-07 30.7 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMR71845.1 - 2.2e-06 27.3 0.0 8.8e-05 22.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMR71845.1 - 5.2e-05 23.2 0.1 0.0041 17.0 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 EMR71845.1 - 0.0021 17.8 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EMR71845.1 - 0.0025 17.3 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 EMR71845.1 - 0.0026 17.8 0.0 0.0049 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EMR71845.1 - 0.0027 17.5 0.1 0.09 12.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EMR71845.1 - 0.01 16.1 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMR71845.1 - 0.012 16.0 0.1 0.021 15.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EMR71845.1 - 0.012 14.9 0.1 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 EMR71845.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMR71845.1 - 0.027 14.0 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 EMR71845.1 - 0.029 14.0 0.0 0.13 11.8 0.0 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EMR71845.1 - 0.073 13.0 0.3 0.13 12.1 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EMR71845.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 EMR71845.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 EMR71845.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Fibrillarin PF01269.17 EMR71846.1 - 4e-101 336.9 0.0 5e-101 336.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EMR71846.1 - 0.00046 19.9 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EMR71846.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F zf-NADH-PPase PF09297.11 EMR71847.1 - 0.064 12.9 0.2 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain SBD_N PF07005.11 EMR71848.1 - 6.1e-62 209.3 0.1 9e-62 208.8 0.1 1.2 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 EMR71848.1 - 8.5e-45 153.3 0.4 3.5e-44 151.3 0.2 2.1 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain Mpp10 PF04006.12 EMR71849.1 - 0.032 12.7 0.9 0.045 12.2 0.9 1.2 1 0 0 1 1 1 0 Mpp10 protein Cyclase PF04199.13 EMR71851.1 - 7.1e-13 49.0 0.0 1.8e-12 47.7 0.0 1.6 1 1 0 1 1 1 1 Putative cyclase MFS_1 PF07690.16 EMR71852.1 - 3.5e-21 75.5 20.3 3.5e-21 75.5 20.3 1.9 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2584 PF10763.9 EMR71852.1 - 0.11 12.7 0.0 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2584) SET PF00856.28 EMR71853.1 - 2.2e-14 54.2 0.0 5.6e-13 49.6 0.0 2.0 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EMR71853.1 - 0.022 15.3 0.1 4.3 8.0 0.1 2.3 2 0 0 2 2 2 0 SAF domain Heme_oxygenase PF01126.20 EMR71855.1 - 3.2e-12 46.7 0.0 2.5e-11 43.8 0.0 2.2 2 1 0 2 2 2 1 Heme oxygenase PHtD_u1 PF16645.5 EMR71855.1 - 0.015 15.7 0.3 0.041 14.3 0.3 1.7 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein DUF1682 PF07946.14 EMR71855.1 - 0.15 11.3 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GFO_IDH_MocA PF01408.22 EMR71856.1 - 7.6e-06 26.7 0.0 2.3e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SAF PF08666.12 EMR71856.1 - 1.1e-05 26.0 0.0 2.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 SAF domain NAD_binding_3 PF03447.16 EMR71856.1 - 2.4e-05 24.9 0.0 0.00013 22.6 0.0 2.2 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.19 EMR71858.1 - 2.1e-40 137.1 0.1 3e-40 136.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 EMR71858.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Lamin Tail Domain EamA PF00892.20 EMR71859.1 - 1.6e-11 44.5 32.1 1.3e-06 28.6 2.6 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 EMR71859.1 - 3e-10 39.8 1.6 3e-10 39.8 1.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 EMR71859.1 - 2.1e-08 33.8 1.7 3.5e-08 33.1 0.1 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 EMR71859.1 - 2.7e-06 27.1 7.0 2.7e-06 27.1 7.0 1.8 2 1 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 EMR71859.1 - 0.033 13.4 13.5 0.0056 15.9 9.7 1.6 2 1 0 2 2 2 0 UAA transporter family CRT-like PF08627.10 EMR71859.1 - 0.038 12.9 0.3 0.038 12.9 0.3 2.8 2 1 0 3 3 3 0 CRT-like, chloroquine-resistance transporter-like Serglycin PF04360.12 EMR71859.1 - 0.11 12.4 0.3 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 Serglycin Dehydrin PF00257.19 EMR71859.1 - 0.17 12.4 0.5 0.34 11.4 0.5 1.4 1 0 0 1 1 1 0 Dehydrin GPI-anchored PF10342.9 EMR71860.1 - 1.2e-07 32.4 0.4 4.8e-07 30.4 0.4 1.8 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FMO-like PF00743.19 EMR71861.1 - 4.4e-25 88.1 0.3 9.8e-15 54.0 0.2 5.0 4 1 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMR71861.1 - 1.4e-07 31.1 0.2 0.0058 15.9 0.0 3.6 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR71861.1 - 2.3e-06 27.1 0.0 6e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR71861.1 - 5.8e-06 25.7 0.1 0.00023 20.4 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMR71861.1 - 0.0013 18.8 0.4 0.23 11.5 0.1 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding ANTH PF07651.16 EMR71861.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Shikimate_DH PF01488.20 EMR71861.1 - 0.22 11.6 0.1 6.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase peroxidase PF00141.23 EMR71862.1 - 8.9e-19 68.1 0.2 1.5e-18 67.4 0.2 1.3 1 0 0 1 1 1 1 Peroxidase SecY PF00344.20 EMR71863.1 - 2e-71 240.8 8.2 2.5e-71 240.4 8.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EMR71863.1 - 1e-17 63.7 0.3 3.2e-17 62.1 0.3 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p ABC_tran PF00005.27 EMR71864.1 - 7e-53 178.8 0.0 2e-30 106.1 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR71864.1 - 7.6e-49 166.8 24.3 1.4e-32 113.5 9.4 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EMR71864.1 - 5.9e-09 35.7 0.9 0.048 13.1 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMR71864.1 - 5.3e-08 33.6 0.5 0.00026 21.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMR71864.1 - 4.9e-05 23.0 0.3 0.31 10.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMR71864.1 - 9.1e-05 22.4 0.1 0.2 11.6 0.1 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 EMR71864.1 - 0.00011 22.1 0.4 1.7 8.4 0.0 3.7 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EMR71864.1 - 0.00045 20.3 0.0 0.056 13.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EMR71864.1 - 0.00064 20.0 0.0 0.8 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EMR71864.1 - 0.00083 19.2 0.0 0.038 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EMR71864.1 - 0.00087 19.7 0.1 0.9 9.9 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain T2SSE PF00437.20 EMR71864.1 - 0.0013 17.9 0.2 0.065 12.3 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 EMR71864.1 - 0.0042 17.2 3.1 0.045 13.8 0.1 3.1 4 0 0 4 4 3 1 Helicase HerA, central domain IstB_IS21 PF01695.17 EMR71864.1 - 0.006 16.3 0.0 3.5 7.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 EMR71864.1 - 0.012 15.2 0.0 0.66 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMR71864.1 - 0.029 13.9 0.1 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 EMR71864.1 - 0.04 13.9 0.0 9.9 6.1 0.1 2.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMR71864.1 - 0.04 13.6 0.2 5.4 6.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EMR71864.1 - 0.048 13.4 0.0 3.1 7.5 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 EMR71864.1 - 0.063 12.6 0.1 7.6 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EMR71864.1 - 0.064 13.6 0.1 12 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 EMR71864.1 - 0.084 12.2 0.3 0.74 9.1 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EMR71864.1 - 0.11 12.6 0.4 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA PF00004.29 EMR71864.1 - 0.13 12.7 0.2 7 7.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EMR71864.1 - 0.13 11.1 2.1 7.9 5.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EMR71864.1 - 0.22 11.1 1.7 2 8.0 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GPI-anchored PF10342.9 EMR71865.1 - 2.5e-07 31.3 0.0 3.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_43 PF04616.14 EMR71866.1 - 2.5e-20 73.0 0.6 5e-20 72.0 0.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EMR71866.1 - 0.0039 16.8 0.1 0.062 12.9 0.0 2.4 2 1 1 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain Ank_2 PF12796.7 EMR71867.1 - 1.3e-24 86.6 0.2 5.2e-09 36.6 0.0 5.8 5 1 0 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.30 EMR71867.1 - 1.3e-24 85.5 3.1 0.00028 21.2 0.3 7.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EMR71867.1 - 2.5e-20 72.6 7.2 9e-05 22.9 0.0 7.3 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR71867.1 - 5.9e-20 69.2 6.0 2.4e-05 24.3 0.1 8.5 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EMR71867.1 - 1.7e-17 63.3 9.6 4.8e-07 29.9 0.0 7.2 5 3 2 7 7 7 3 Ankyrin repeats (many copies) adh_short PF00106.25 EMR71868.1 - 8.3e-33 113.5 0.0 1.5e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71868.1 - 3.5e-23 82.4 0.0 5.7e-23 81.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMR71868.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR71868.1 - 0.015 15.2 0.8 7.6 6.4 0.0 2.7 2 1 0 2 2 2 0 KR domain Eno-Rase_NADH_b PF12242.8 EMR71868.1 - 0.032 14.0 1.0 0.12 12.1 0.6 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PheRS_DBD2 PF18554.1 EMR71868.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Metallophos PF00149.28 EMR71869.1 - 1.1e-06 29.4 0.1 1.8e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DnaJ PF00226.31 EMR71871.1 - 8.6e-19 67.4 1.8 8.6e-19 67.4 1.8 2.0 2 0 0 2 2 2 1 DnaJ domain Dioxygenase_C PF00775.21 EMR71872.1 - 3.1e-05 23.5 0.0 0.00017 21.1 0.0 2.0 1 1 0 1 1 1 1 Dioxygenase DUF4707 PF15806.5 EMR71872.1 - 0.066 12.2 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) IPPT PF01715.17 EMR71873.1 - 1.5e-62 211.4 0.4 2.1e-62 210.9 0.4 1.2 1 0 0 1 1 1 1 IPP transferase OrsD PF12013.8 EMR71873.1 - 0.0072 16.8 1.8 0.14 12.6 0.8 2.6 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4635 PF15466.6 EMR71873.1 - 0.052 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) SUIM_assoc PF16619.5 EMR71873.1 - 0.85 9.7 5.3 3.1 7.9 0.2 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 MBOAT PF03062.19 EMR71874.1 - 1.3e-40 139.9 18.9 2.4e-39 135.7 12.8 2.2 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Ank_2 PF12796.7 EMR71876.1 - 1.7e-27 95.8 0.8 3e-13 50.2 0.2 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR71876.1 - 7.6e-13 48.7 0.0 2.1e-07 31.4 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR71876.1 - 8.4e-12 44.2 0.1 0.0053 17.2 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EMR71876.1 - 1.8e-11 43.9 1.5 0.00028 21.2 0.1 4.9 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EMR71876.1 - 4.4e-11 42.8 2.0 0.00022 21.4 0.2 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) DUF2428 PF10350.9 EMR71877.1 - 1e-46 159.4 0.4 8.8e-46 156.4 0.1 2.3 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 EMR71877.1 - 0.005 17.2 7.8 0.82 10.1 0.6 4.9 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EMR71877.1 - 0.0052 16.9 19.2 2.7 8.5 0.4 7.1 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 EMR71877.1 - 0.046 13.8 0.3 30 4.6 0.0 3.6 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EMR71877.1 - 0.87 10.2 0.0 0.87 10.2 0.0 4.6 5 0 0 5 5 5 0 HEAT-like repeat VASt PF16016.5 EMR71878.1 - 2.9e-31 109.0 0.8 5.4e-31 108.1 0.8 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF956 PF06115.11 EMR71878.1 - 0.085 12.6 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF956) DUF1330 PF07045.11 EMR71879.1 - 0.0016 18.7 0.1 0.0029 17.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) MMR_HSR1_Xtn PF16897.5 EMR71880.1 - 1.6e-40 137.4 0.4 1.2e-39 134.6 0.4 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EMR71880.1 - 1.4e-20 73.5 0.0 6.6e-20 71.3 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EMR71880.1 - 9.5e-19 67.2 0.0 1.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EMR71880.1 - 1.3e-08 34.6 0.0 5.4e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EMR71880.1 - 0.00074 19.6 0.0 0.15 12.1 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 EMR71880.1 - 0.00079 19.0 0.1 5.7 6.4 0.0 3.8 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 EMR71880.1 - 0.017 14.1 0.2 0.063 12.2 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EMR71880.1 - 0.022 15.0 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 EMR71880.1 - 0.029 13.8 0.1 5 6.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EMR71880.1 - 0.07 13.0 0.2 5.3 6.9 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase Methyltransf_23 PF13489.6 EMR71882.1 - 8.6e-08 32.2 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR71882.1 - 7.2e-05 23.4 0.1 0.00047 20.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR71882.1 - 0.0024 18.6 0.0 0.015 16.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR71882.1 - 0.087 13.5 0.0 0.35 11.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF3074 PF11274.8 EMR71883.1 - 2.4e-32 112.4 8.1 1.3e-23 84.0 0.1 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3074) AAA_13 PF13166.6 EMR71883.1 - 1.7 7.2 22.1 2.9 6.4 22.1 1.3 1 0 0 1 1 1 0 AAA domain Tim17 PF02466.19 EMR71884.1 - 8.2e-24 84.1 5.5 1.3e-23 83.5 5.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pex14_N PF04695.13 EMR71884.1 - 0.53 10.9 7.7 22 5.7 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PS-DH PF14765.6 EMR71885.1 - 8.4e-69 232.1 0.2 1.3e-68 231.4 0.2 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EMR71885.1 - 4.4e-60 203.4 0.1 1.4e-59 201.8 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EMR71885.1 - 3e-57 193.4 0.0 6.8e-57 192.3 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EMR71885.1 - 1.3e-50 172.8 0.0 2.4e-50 171.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR71885.1 - 1.8e-37 128.0 0.0 3.5e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EMR71885.1 - 8.2e-26 90.7 0.0 2.4e-25 89.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EMR71885.1 - 5.6e-18 65.5 0.0 3.8e-17 62.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 EMR71885.1 - 3.3e-13 49.8 0.0 2.9e-11 43.5 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR71885.1 - 7.2e-13 49.7 0.0 4.5e-12 47.2 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EMR71885.1 - 1.6e-11 44.3 0.0 3.9e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR71885.1 - 7.2e-09 36.2 0.0 2.5e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR71885.1 - 2.6e-07 31.2 0.0 8e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR71885.1 - 8.1e-07 29.0 0.0 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 EMR71885.1 - 1.3e-06 28.0 0.0 1.3e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 EMR71885.1 - 1.9e-06 28.1 0.1 5.7e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EMR71885.1 - 5.4e-06 26.3 0.0 1.7e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 EMR71885.1 - 0.00038 20.1 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NodS PF05401.11 EMR71885.1 - 0.02 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) PPP4R2 PF09184.11 EMR71886.1 - 1 8.9 8.1 1.3 8.6 8.1 1.1 1 0 0 1 1 1 0 PPP4R2 SH3_1 PF00018.28 EMR71887.1 - 0.00041 19.9 0.0 0.00098 18.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain HTH_Tnp_Tc5 PF03221.16 EMR71888.1 - 1.1e-09 38.1 0.0 3.7e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_4 PF13613.6 EMR71888.1 - 0.0028 17.3 0.0 0.0084 15.8 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease LysM PF01476.20 EMR71889.1 - 2.6e-05 24.2 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 LysM domain Baculo_IE-1 PF05290.11 EMR71889.1 - 0.011 15.7 1.6 0.017 15.1 1.6 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) UBA_4 PF14555.6 EMR71889.1 - 0.036 13.9 0.4 0.067 13.0 0.4 1.4 1 0 0 1 1 1 0 UBA-like domain Methyltransf_16 PF10294.9 EMR71890.1 - 6.2e-09 35.8 0.0 6.1e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase SesA PF17107.5 EMR71891.1 - 0.0055 16.9 0.1 0.026 14.7 0.1 1.8 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases EF-hand_7 PF13499.6 EMR71892.1 - 4.3e-25 88.0 8.7 1.4e-16 60.7 1.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EMR71892.1 - 1.7e-24 83.6 4.7 5.3e-06 25.9 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 EMR71892.1 - 2.1e-24 83.2 13.8 3.2e-08 32.5 0.2 4.8 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 EMR71892.1 - 3.3e-18 64.3 14.2 3.8e-05 23.0 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EMR71892.1 - 1e-14 54.1 12.1 5.2e-05 23.0 1.0 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EMR71892.1 - 2.1e-09 37.2 8.1 0.0049 16.8 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EMR71892.1 - 7.3e-05 23.0 0.5 0.0079 16.5 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EMR71892.1 - 0.0003 21.1 3.3 0.96 9.8 0.4 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 EMR71892.1 - 0.036 12.9 0.3 1.8 7.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 EMR71892.1 - 0.075 12.9 5.1 0.27 11.1 0.0 3.6 5 0 0 5 5 5 0 EF hand EF-hand_14 PF17959.1 EMR71892.1 - 0.13 12.6 2.9 10 6.5 0.0 3.7 3 1 0 3 3 3 0 EF-hand domain Reo_sigmaC PF04582.12 EMR71893.1 - 0.13 12.5 0.0 0.47 10.7 0.0 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain adh_short PF00106.25 EMR71895.1 - 3.9e-32 111.3 0.0 7.2e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71895.1 - 2.7e-21 76.2 0.0 5.8e-21 75.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EMR71895.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR71895.1 - 2.3e-05 24.4 0.4 4.8e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EMR71895.1 - 0.00049 19.6 0.0 0.07 12.6 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMR71895.1 - 0.0016 17.9 0.0 0.0066 15.9 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ApbA PF02558.16 EMR71895.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EMR71895.1 - 0.036 14.3 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain PALP PF00291.25 EMR71895.1 - 0.04 13.3 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAD_binding_2 PF03446.15 EMR71895.1 - 0.043 14.0 0.0 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EMR71895.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain QRPTase_C PF01729.19 EMR71895.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain AMP-binding PF00501.28 EMR71896.1 - 2.9e-87 293.0 0.0 4.3e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR71896.1 - 0.037 15.0 0.0 0.097 13.7 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain CDC45 PF02724.14 EMR71897.1 - 1.3e-103 347.5 27.5 3.5e-101 339.5 27.5 3.0 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 EMR71897.1 - 0.0034 17.2 11.4 0.0063 16.3 11.4 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CNDH2_C PF16858.5 EMR71897.1 - 0.0057 16.6 2.5 0.01 15.8 2.5 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAM60A PF15396.6 EMR71897.1 - 0.011 15.8 1.7 0.017 15.1 1.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CSRNP_N PF16019.5 EMR71897.1 - 0.06 13.3 2.1 0.1 12.5 2.1 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus SAPS PF04499.15 EMR71897.1 - 0.067 12.0 0.5 0.066 12.0 0.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Syntaxin-18_N PF10496.9 EMR71897.1 - 0.093 13.0 3.6 2.8 8.2 4.3 2.6 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus BUD22 PF09073.10 EMR71897.1 - 0.16 11.3 16.9 0.26 10.6 16.9 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EMR71897.1 - 1.1 7.4 15.7 1.6 6.8 15.7 1.2 1 0 0 1 1 1 0 Nop14-like family PIEZO PF15917.5 EMR71897.1 - 3.1 7.2 8.1 6 6.3 8.1 1.4 1 0 0 1 1 1 0 Piezo NPR3 PF03666.13 EMR71897.1 - 3.3 6.4 8.8 5.2 5.7 8.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 EMR71897.1 - 4.2 6.5 5.5 6.3 5.9 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Afi1 PF07792.12 EMR71897.1 - 6.7 7.2 10.2 14 6.2 10.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PUF PF00806.19 EMR71898.1 - 2.4e-60 196.9 11.0 1.1e-08 34.3 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EMR71898.1 - 0.00012 22.4 0.2 7.2 7.0 0.0 4.7 1 1 2 4 4 4 3 CPL (NUC119) domain MgtE_N PF03448.17 EMR71898.1 - 0.2 12.3 0.1 0.46 11.1 0.1 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain Cellulase PF00150.18 EMR71899.1 - 8.6e-16 58.2 1.5 1.3e-15 57.6 1.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DAO PF01266.24 EMR71900.1 - 4.6e-32 112.0 0.0 5.5e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR71900.1 - 2.4e-07 30.9 0.0 7.2e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR71900.1 - 0.00045 19.6 0.1 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EMR71900.1 - 0.001 19.1 0.0 0.025 14.6 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EMR71900.1 - 0.0022 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EMR71900.1 - 0.0043 17.1 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EMR71900.1 - 0.0098 15.0 0.3 0.13 11.4 0.1 2.1 1 1 1 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 EMR71900.1 - 0.02 14.8 0.1 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EMR71900.1 - 0.023 13.8 0.2 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMR71900.1 - 0.041 13.1 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.23 EMR71900.1 - 0.049 13.7 0.0 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMR71900.1 - 0.05 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 EMR71900.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EMR71900.1 - 0.12 12.9 0.0 0.62 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Velvet PF11754.8 EMR71901.1 - 0.0002 21.4 0.1 0.0002 21.4 0.1 1.9 1 1 1 2 2 2 1 Velvet factor MAGE_N PF12440.8 EMR71901.1 - 0.001 19.7 30.2 0.11 13.2 5.1 3.7 3 0 0 3 3 3 3 Melanoma associated antigen family N terminal DUF1987 PF09345.10 EMR71901.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1987) Ribosomal_60s PF00428.19 EMR71901.1 - 0.23 12.1 6.3 0.084 13.5 2.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein WRNPLPNID PF15017.6 EMR71901.1 - 1.9 9.4 7.8 0.75 10.7 1.9 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Apt1 PF10351.9 EMR71901.1 - 4.2 6.1 6.8 0.99 8.2 2.1 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 EMR71901.1 - 4.4 5.3 21.7 0.45 8.5 7.5 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PSP1 PF04468.12 EMR71902.1 - 1e-28 99.4 1.6 1.7e-28 98.7 1.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.11 EMR71903.1 - 4.9e-30 103.4 0.2 1.6e-29 101.8 0.0 1.9 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EMR71903.1 - 5e-28 97.1 0.1 8.1e-28 96.4 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Abhydrolase_6 PF12697.7 EMR71904.1 - 2.3e-11 44.8 0.2 2.7e-11 44.5 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EMR71904.1 - 0.011 15.4 0.5 0.03 14.1 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DUF900 PF05990.12 EMR71904.1 - 0.014 14.9 0.0 0.034 13.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.12 EMR71904.1 - 0.038 13.6 0.2 0.062 12.9 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase p450 PF00067.22 EMR71906.1 - 1.3e-49 169.2 0.0 1.2e-48 166.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb2_6 PF00562.28 EMR71907.1 - 3.9e-122 408.1 0.0 6.2e-122 407.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EMR71907.1 - 1.3e-49 168.5 0.0 1.9e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EMR71907.1 - 7.6e-33 112.8 0.6 1.8e-32 111.6 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EMR71907.1 - 6.5e-26 91.1 0.0 1.9e-25 89.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EMR71907.1 - 4.8e-22 78.0 0.1 1.3e-21 76.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EMR71907.1 - 2.4e-19 69.2 0.0 4.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EMR71907.1 - 3e-11 43.7 0.3 8.2e-11 42.3 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 XhlA PF10779.9 EMR71908.1 - 2.8 8.2 5.5 5 7.4 0.2 3.4 4 0 0 4 4 4 0 Haemolysin XhlA zf-HIT PF04438.16 EMR71909.1 - 4e-05 23.4 7.5 5.7e-05 22.9 7.5 1.2 1 0 0 1 1 1 1 HIT zinc finger Amidohydro_1 PF01979.20 EMR71910.1 - 4.1e-40 138.1 0.0 5e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR71910.1 - 7.1e-16 58.7 3.1 7.9e-10 38.8 0.4 2.4 2 1 0 2 2 2 2 Amidohydrolase family Chorion_3 PF05387.11 EMR71910.1 - 0.1 12.2 3.0 0.19 11.3 3.0 1.4 1 0 0 1 1 1 0 Chorion family 3 Rad51 PF08423.11 EMR71911.1 - 1.7e-33 115.9 0.0 2.6e-20 72.8 0.0 2.4 2 0 0 2 2 2 2 Rad51 ATPase PF06745.13 EMR71911.1 - 6.1e-07 29.0 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.21 EMR71911.1 - 7.7e-06 25.6 0.0 2.3e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EMR71911.1 - 1.3e-05 24.9 0.1 7.7e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMR71911.1 - 0.0098 16.3 0.8 0.021 15.2 0.8 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EMR71911.1 - 0.014 15.9 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 EMR71911.1 - 0.036 13.3 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Serglycin PF04360.12 EMR71911.1 - 0.053 13.5 0.2 0.14 12.1 0.2 1.7 1 0 0 1 1 1 0 Serglycin AAA_22 PF13401.6 EMR71911.1 - 0.058 13.7 0.9 0.3 11.4 0.0 2.5 2 1 1 3 3 3 0 AAA domain EPL1 PF10513.9 EMR71911.1 - 0.091 13.1 8.7 5.7 7.3 0.2 3.1 3 0 0 3 3 3 0 Enhancer of polycomb-like OHCU_decarbox PF09349.10 EMR71911.1 - 0.14 12.7 1.7 4.2 7.9 0.1 2.3 2 0 0 2 2 2 0 OHCU decarboxylase SUIM_assoc PF16619.5 EMR71911.1 - 0.27 11.3 8.3 0.3 11.2 2.5 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 CDC45 PF02724.14 EMR71911.1 - 3.9 5.6 5.6 1.3 7.3 0.1 2.0 2 0 0 2 2 2 0 CDC45-like protein SKG6 PF08693.10 EMR71912.1 - 0.0049 16.3 1.5 0.011 15.1 1.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.18 EMR71912.1 - 0.0094 16.2 0.2 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 Glycophorin A YajC PF02699.15 EMR71912.1 - 0.02 14.7 1.6 0.043 13.7 1.6 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Alpha_GJ PF03229.13 EMR71912.1 - 0.023 15.3 3.0 0.023 15.3 3.0 2.5 3 0 0 3 3 3 0 Alphavirus glycoprotein J DUF2681 PF10883.8 EMR71912.1 - 0.063 13.7 0.4 0.1 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EphA2_TM PF14575.6 EMR71912.1 - 0.1 13.5 0.0 0.22 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 EMR71912.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF533 PF04391.12 EMR71912.1 - 0.16 11.5 0.6 0.27 10.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Podoplanin PF05808.11 EMR71912.1 - 0.26 11.4 4.2 0.45 10.6 4.2 1.3 1 0 0 1 1 1 0 Podoplanin EHN PF06441.12 EMR71914.1 - 6.3e-29 100.5 0.1 9.8e-29 99.9 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMR71914.1 - 5.8e-06 26.1 0.0 7.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 EMR71915.1 - 7.1e-27 94.2 61.6 5.1e-25 88.2 56.6 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR71915.1 - 9.3e-13 47.8 0.8 9.3e-13 47.8 0.8 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter PNP_UDP_1 PF01048.20 EMR71916.1 - 8.9e-14 51.3 0.9 2.2e-13 50.0 0.9 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily APH PF01636.23 EMR71917.1 - 2.2e-06 27.8 0.3 6.4e-06 26.3 0.3 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMR71917.1 - 0.0055 16.3 0.0 0.0087 15.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EMR71917.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) p450 PF00067.22 EMR71918.1 - 4.2e-42 144.5 0.0 5e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2052 PF09747.9 EMR71919.1 - 0.18 11.9 1.9 0.24 11.5 1.9 1.3 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Beta_helix PF13229.6 EMR71920.1 - 0.013 15.4 3.4 0.2 11.5 2.7 2.6 1 1 1 2 2 2 0 Right handed beta helix region Big_3_5 PF16640.5 EMR71920.1 - 6.5 7.0 8.1 11 6.2 3.0 3.4 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) MMU163 PF17119.5 EMR71921.1 - 5.1e-79 264.9 5.8 2e-59 200.8 0.9 2.0 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Tom5 PF10642.9 EMR71921.1 - 0.059 13.4 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DUF5058 PF16481.5 EMR71921.1 - 0.079 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) adh_short PF00106.25 EMR71922.1 - 5.9e-42 143.3 1.4 7.8e-42 143.0 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71922.1 - 1e-35 123.4 1.1 1.6e-35 122.7 1.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71922.1 - 1.5e-08 34.8 0.5 1.8e-08 34.5 0.5 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR71922.1 - 4.5e-07 29.9 0.1 9.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EMR71922.1 - 9e-05 23.0 0.2 0.00018 22.1 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 EMR71922.1 - 0.0019 17.6 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EMR71922.1 - 0.0071 15.9 0.3 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 EMR71922.1 - 0.067 13.2 0.3 0.11 12.4 0.3 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 EMR71922.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L15e PF00827.17 EMR71923.1 - 3.5e-90 300.8 10.4 4.3e-90 300.6 10.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 DJ-1_PfpI PF01965.24 EMR71924.1 - 1.9e-16 60.3 0.0 1.1e-15 57.8 0.0 2.2 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMR71924.1 - 2.4e-08 33.9 0.0 2.9e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like Carn_acyltransf PF00755.20 EMR71925.1 - 2.8e-207 690.0 0.0 6.8e-207 688.7 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase AcetylCoA_hyd_C PF13336.6 EMR71925.1 - 0.044 13.7 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Nramp PF01566.18 EMR71926.1 - 1.5e-89 300.5 18.5 1.5e-89 300.5 18.5 2.2 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Ysc84 PF04366.12 EMR71927.1 - 2.2e-26 92.1 0.1 3.6e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EMR71927.1 - 6.6e-14 51.3 0.0 1.1e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMR71927.1 - 3.1e-13 49.2 0.5 2.2e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EMR71927.1 - 1.6e-12 47.1 0.0 3.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 EMR71927.1 - 0.035 13.8 0.1 0.067 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) FGGY_C PF02782.16 EMR71928.1 - 1.8e-72 243.3 2.6 1.8e-72 243.3 2.6 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EMR71928.1 - 1.7e-54 185.0 0.0 2.5e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain RINT1_TIP1 PF04437.13 EMR71929.1 - 0.091 11.6 2.0 0.17 10.7 0.1 1.8 1 1 0 2 2 2 0 RINT-1 / TIP-1 family TFB6 PF17110.5 EMR71929.1 - 0.1 12.3 15.2 0.45 10.2 4.7 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH BUD22 PF09073.10 EMR71929.1 - 0.12 11.7 17.3 0.16 11.3 17.3 1.1 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 EMR71929.1 - 0.91 9.2 16.4 1.6 8.4 1.3 2.1 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.13 EMR71929.1 - 1.1 9.1 21.6 0.048 13.5 6.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.12 EMR71929.1 - 1.1 8.5 27.1 0.15 11.3 11.5 2.1 2 0 0 2 2 2 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EMR71929.1 - 1.3 8.7 21.1 0.051 13.3 6.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 EMR71929.1 - 3.1 7.8 16.7 2.2 8.3 6.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal WRNPLPNID PF15017.6 EMR71929.1 - 5.1 8.0 22.4 10 7.1 9.8 2.3 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box GP67 PF17634.2 EMR71929.1 - 9.3 6.7 33.3 1.7 9.1 15.4 2.3 2 0 0 2 2 2 0 Gene product 67 ArfGap PF01412.18 EMR71930.1 - 4.8e-40 136.3 0.5 7.3e-40 135.7 0.5 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 EMR71930.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Lactamase_B_2 PF12706.7 EMR71931.1 - 7.1e-27 94.2 0.0 1.6e-25 89.8 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMR71931.1 - 8.5e-09 35.5 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMR71931.1 - 0.0069 16.4 0.6 0.04 13.9 0.5 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RXT2_N PF08595.11 EMR71933.1 - 5.2e-30 104.5 1.6 5.2e-30 104.5 1.6 2.3 2 0 0 2 2 2 1 RXT2-like, N-terminal RTP1_C1 PF10363.9 EMR71934.1 - 1.8e-29 102.2 0.1 8.2e-29 100.1 0.1 2.2 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EMR71934.1 - 1.9e-09 37.0 0.5 5.5e-09 35.5 0.5 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 EMR71934.1 - 0.018 15.6 2.2 7.4 7.2 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.7 EMR71934.1 - 0.046 13.8 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 SLAC1 PF03595.17 EMR71935.1 - 1.1e-50 172.8 32.5 1.5e-50 172.4 32.5 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel Synaptobrevin PF00957.21 EMR71937.1 - 0.0098 15.7 0.7 0.046 13.5 0.4 1.9 1 1 1 2 2 2 1 Synaptobrevin Phage_holin_2_4 PF16082.5 EMR71937.1 - 0.059 13.1 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like PEMT PF04191.13 EMR71938.1 - 4.4e-33 113.8 2.7 1.6e-32 112.1 2.4 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase Gryzun PF07919.12 EMR71939.1 - 2.1e-98 330.7 0.5 1.9e-97 327.5 0.5 2.3 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 EMR71939.1 - 0.0078 16.2 0.0 0.058 13.4 0.0 2.1 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking DNA_pol_phi PF04931.13 EMR71939.1 - 1.1 7.3 13.9 1.3 7.0 13.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi GMC_oxred_C PF05199.13 EMR71940.1 - 1.2e-27 97.2 0.0 2.1e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR71940.1 - 4.1e-27 95.3 0.0 2.4e-24 86.2 0.0 2.9 1 1 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 EMR71940.1 - 0.00014 21.2 0.0 0.00082 18.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMR71940.1 - 0.0037 16.4 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMR71940.1 - 0.0044 16.1 0.5 0.0089 15.2 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EMR71940.1 - 0.0046 17.2 0.2 0.01 16.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 EMR71940.1 - 0.072 12.4 0.2 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 EMR71940.1 - 0.074 12.3 0.0 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase VSP PF03302.13 EMR71941.1 - 0.00015 20.8 0.6 0.00024 20.1 0.6 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 EMR71941.1 - 0.018 14.4 9.2 0.038 13.4 9.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 EMR71941.1 - 0.027 14.2 0.2 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4690 PF15756.5 EMR71941.1 - 0.036 14.7 1.5 0.036 14.7 1.5 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Rax2 PF12768.7 EMR71941.1 - 0.08 12.4 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DAP10 PF07213.11 EMR71941.1 - 0.081 12.9 0.8 0.2 11.7 0.8 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Podoplanin PF05808.11 EMR71941.1 - 0.77 9.8 11.9 0.26 11.4 4.1 2.8 2 1 1 3 3 3 0 Podoplanin Tub_N PF16322.5 EMR71941.1 - 2.4 8.5 6.5 0.12 12.8 0.5 1.8 2 0 0 2 2 2 0 Tubby N-terminal Pex14_N PF04695.13 EMR71941.1 - 7.5 7.2 7.1 4.7 7.8 0.1 3.0 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPRY PF00622.28 EMR71942.1 - 0.0057 16.8 0.0 0.068 13.3 0.0 2.4 2 0 0 2 2 2 1 SPRY domain Tir_receptor_C PF07489.11 EMR71942.1 - 0.84 9.6 4.7 2 8.4 4.7 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Peptidase_S8 PF00082.22 EMR71944.1 - 1.9e-46 158.7 7.5 2.9e-46 158.1 7.5 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EMR71944.1 - 5e-09 36.9 0.1 1.6e-08 35.2 0.1 1.9 1 1 0 1 1 1 1 Fn3-like domain PA PF02225.22 EMR71944.1 - 0.00075 19.5 0.7 0.0026 17.7 0.1 2.2 2 0 0 2 2 2 1 PA domain Sterol_MT_C PF08498.10 EMR71945.1 - 1.4e-27 95.8 0.1 2.7e-27 94.9 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EMR71945.1 - 4.9e-21 75.2 0.0 1.1e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR71945.1 - 7.2e-20 71.5 0.0 2.1e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR71945.1 - 2.2e-17 63.2 0.0 3.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMR71945.1 - 2.7e-12 46.6 0.0 3.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EMR71945.1 - 5.9e-12 45.7 0.0 9.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR71945.1 - 3.3e-11 43.0 0.0 8.7e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMR71945.1 - 2.4e-10 41.0 0.0 6.6e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EMR71945.1 - 0.0014 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 EMR71945.1 - 0.0051 15.4 0.0 0.0093 14.6 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 EMR71945.1 - 0.0096 15.7 0.0 0.025 14.3 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EMR71945.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 EMR71945.1 - 0.019 14.4 0.0 0.051 13.0 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EMR71945.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 EMR71945.1 - 0.035 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF4035 PF13227.6 EMR71945.1 - 0.093 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) MTS PF05175.14 EMR71945.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Abhydrolase_4 PF08386.10 EMR71946.1 - 6.5e-17 61.5 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EMR71946.1 - 0.042 13.5 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.25 EMR71947.1 - 4.2e-08 32.9 0.0 3.7e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR71947.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Cyto_heme_lyase PF01265.17 EMR71948.1 - 4.6e-103 344.8 0.4 5.3e-103 344.6 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.16 EMR71949.1 - 8.2e-24 84.1 0.0 1.2e-13 51.2 0.0 2.4 1 1 1 2 2 2 2 ABC1 family APH PF01636.23 EMR71949.1 - 0.00035 20.6 1.0 0.0013 18.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EMR71949.1 - 0.23 10.8 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain K_oxygenase PF13434.6 EMR71950.1 - 1.4e-110 369.7 0.0 1.6e-110 369.4 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMR71950.1 - 2.2e-08 33.7 0.0 2.9e-07 30.0 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR71950.1 - 5.4e-06 25.8 0.0 0.00035 19.9 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR71950.1 - 0.0015 18.6 0.0 0.027 14.5 0.0 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding p450 PF00067.22 EMR71951.1 - 7.2e-67 226.1 0.0 1e-66 225.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LPD13 PF18825.1 EMR71952.1 - 0.15 11.8 0.1 0.44 10.3 0.1 1.8 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 13 4HBT_2 PF13279.6 EMR71953.1 - 3.2e-06 27.6 0.0 3.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Spike_torovirin PF17072.5 EMR71953.1 - 0.13 9.3 0.0 0.16 9.1 0.0 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein Peroxidase_2 PF01328.17 EMR71954.1 - 1.8e-30 106.8 0.5 2.5e-30 106.4 0.5 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Condensation PF00668.20 EMR71955.1 - 3.7e-33 114.9 0.0 7.1e-25 87.6 0.0 3.3 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EMR71955.1 - 1.7e-11 44.3 0.2 6.1e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site WES_acyltransf PF03007.16 EMR71955.1 - 0.00067 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain PTR2 PF00854.21 EMR71957.1 - 1.5e-51 175.5 9.5 2.1e-51 175.0 9.5 1.3 1 0 0 1 1 1 1 POT family Phage_holin_3_6 PF07332.11 EMR71957.1 - 0.01 15.9 0.8 0.01 15.9 0.8 4.1 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4311 PF14188.6 EMR71957.1 - 0.15 11.8 5.5 0.083 12.7 1.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4311) CcmH PF03918.14 EMR71957.1 - 0.32 10.3 0.7 38 3.6 0.0 3.0 2 1 1 3 3 3 0 Cytochrome C biogenesis protein Lipoxygenase PF00305.19 EMR71959.1 - 4.3e-29 101.5 0.0 5.7e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase MFS_1 PF07690.16 EMR71960.1 - 1.5e-30 106.4 39.3 1.9e-30 106.0 39.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PRIMA1 PF16101.5 EMR71960.1 - 0.17 11.9 0.8 4.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 HET PF06985.11 EMR71962.1 - 6.2e-23 81.8 0.4 9.5e-23 81.2 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FTP PF07504.13 EMR71963.1 - 6.2e-19 67.6 2.7 9.2e-19 67.0 2.7 1.3 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF4901 PF16244.5 EMR71963.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) p450 PF00067.22 EMR71964.1 - 1.1e-30 106.8 0.0 1.9e-21 76.3 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Phasin_2 PF09361.10 EMR71964.1 - 0.088 13.1 0.3 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 Phasin protein Fungal_trans PF04082.18 EMR71965.1 - 0.027 13.5 0.2 0.057 12.4 0.1 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain TFIIA PF03153.13 EMR71965.1 - 0.33 10.9 10.3 0.47 10.4 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRR1 PF07985.12 EMR71966.1 - 1.4e-05 25.0 0.6 0.00045 20.2 0.6 2.4 1 1 0 1 1 1 1 SRR1 Ricin_B_lectin PF00652.22 EMR71967.1 - 4.6e-07 30.1 0.0 0.0039 17.4 0.0 3.2 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain Cript PF10235.9 EMR71968.1 - 0.14 12.8 0.3 0.37 11.4 0.3 1.7 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Tat PF00539.18 EMR71968.1 - 0.75 10.0 3.8 1.3 9.2 0.3 2.7 3 0 0 3 3 3 0 Transactivating regulatory protein (Tat) NAD_binding_8 PF13450.6 EMR71969.1 - 1.2e-06 28.6 0.2 5e-06 26.6 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR71969.1 - 0.001 18.4 0.1 2.8 7.1 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMR71969.1 - 0.0085 14.6 0.0 0.11 10.8 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 EMR71969.1 - 0.0088 16.0 1.6 2 8.4 0.1 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 EMR71969.1 - 0.037 13.4 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMR71969.1 - 0.058 13.5 0.0 0.85 9.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 EMR71969.1 - 0.07 12.3 0.0 7.5 5.6 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cyclase PF04199.13 EMR71970.1 - 1.4e-16 61.0 0.2 2.2e-16 60.3 0.2 1.4 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.12 EMR71970.1 - 0.15 11.8 0.0 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Polysacc_deac_1 PF01522.21 EMR71971.1 - 1.8e-06 27.8 0.0 3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EMR71971.1 - 0.0065 15.7 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 WW PF00397.26 EMR71972.1 - 5.4e-06 26.4 4.0 5.4e-06 26.4 4.0 2.3 3 0 0 3 3 3 1 WW domain KinB_sensor PF16767.5 EMR71972.1 - 0.031 14.7 2.2 0.048 14.1 2.2 1.2 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF4404 PF14357.6 EMR71972.1 - 0.15 12.7 3.3 0.28 11.8 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) p450 PF00067.22 EMR71974.1 - 3.5e-42 144.7 0.0 1.3e-34 119.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 adh_short PF00106.25 EMR71975.1 - 1.4e-36 125.8 0.0 1.7e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR71975.1 - 1.8e-26 93.2 0.0 2.2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR71975.1 - 7.3e-10 39.0 0.2 9.5e-10 38.7 0.2 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EMR71975.1 - 0.0065 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 EMR71975.1 - 0.041 13.6 0.3 0.37 10.6 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.21 EMR71975.1 - 0.069 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 ThiF family Peptidase_C14 PF00656.22 EMR71976.1 - 5.9e-61 206.6 0.0 7.9e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CF222 PF15661.5 EMR71976.1 - 0.081 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 C6orf222, uncharacterised family HCO3_cotransp PF00955.21 EMR71977.1 - 9.4e-87 291.9 10.6 1.5e-45 156.0 5.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family TNFR_16_TM PF18422.1 EMR71977.1 - 0.045 13.7 0.8 0.045 13.7 0.8 2.9 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Med8 PF10232.9 EMR71978.1 - 6.6e-16 58.6 0.0 1.8e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Det1 PF09737.9 EMR71978.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Dicty_REP PF05086.12 EMR71978.1 - 0.43 8.5 2.6 0.49 8.3 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HATPase_c PF02518.26 EMR71980.1 - 6.5e-30 103.9 0.2 1.2e-29 103.0 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMR71980.1 - 1.2e-22 80.2 0.1 2.7e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EMR71980.1 - 4.7e-22 77.8 0.3 1.5e-21 76.2 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EMR71980.1 - 0.0017 18.2 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rif1_N PF12231.8 EMR71981.1 - 8.1e-151 502.3 1.0 1e-150 501.9 1.0 1.1 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal DIOX_N PF14226.6 EMR71982.1 - 2.6e-14 54.0 0.0 4.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMR71982.1 - 1e-13 51.6 0.0 2.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4073 PF13285.6 EMR71982.1 - 0.0017 18.0 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4073) LigD_N PF13298.6 EMR71983.1 - 1.2e-16 60.9 0.0 7.4e-07 29.4 0.1 2.7 1 1 1 2 2 2 2 DNA polymerase Ligase (LigD) Sporozoite_P67 PF05642.11 EMR71983.1 - 0.21 9.6 9.3 1.4 6.9 0.2 2.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Chromo PF00385.24 EMR71984.1 - 1.9e-17 62.9 0.9 3.5e-17 62.0 0.9 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PQ-loop PF04193.14 EMR71985.1 - 5.1e-24 83.8 6.7 4.3e-15 55.2 0.8 2.7 3 0 0 3 3 3 2 PQ loop repeat CCD PF07860.11 EMR71985.1 - 0.059 13.4 0.8 0.12 12.4 0.8 1.5 1 0 0 1 1 1 0 WisP family C-Terminal Region Condensation PF00668.20 EMR71986.1 - 2.7e-22 79.1 0.0 3.6e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Condensation domain Transferase PF02458.15 EMR71986.1 - 0.0012 17.6 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Transferase family Aldose_epim PF01263.20 EMR71987.1 - 5.2e-39 134.3 0.0 6.3e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.16 EMR71989.1 - 9.4e-192 637.3 0.0 1.1e-191 637.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Sulfatase PF00884.23 EMR71990.1 - 5.4e-49 167.2 0.1 7.3e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EMR71990.1 - 3e-25 87.8 0.5 7e-25 86.6 0.5 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EMR71990.1 - 1.2e-06 28.4 0.0 0.0034 17.0 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EMR71990.1 - 0.0013 19.5 0.7 0.0039 17.9 0.7 1.9 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 EMR71990.1 - 0.0019 16.9 0.0 0.0029 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Dynein_light PF01221.18 EMR71991.1 - 2.7e-40 136.6 0.9 3e-40 136.4 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 FDC-SP PF15215.6 EMR71992.1 - 0.032 14.8 1.9 0.032 14.8 1.9 2.5 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide zinc_ribbon_15 PF17032.5 EMR71993.1 - 0.0001 23.0 1.1 0.00015 22.4 1.1 1.2 1 0 0 1 1 1 1 zinc-ribbon family PriA_CRR PF18319.1 EMR71993.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.4 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain TEA PF01285.18 EMR71994.1 - 0.00011 22.2 0.1 0.00027 20.9 0.1 1.8 1 0 0 1 1 1 1 TEA/ATTS domain SMN PF06003.12 EMR71994.1 - 0.46 9.7 10.1 0.02 14.2 4.0 1.8 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Mem_trans PF03547.18 EMR71994.1 - 0.99 7.7 2.0 1.6 7.0 2.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Otopetrin PF03189.13 EMR71994.1 - 2.8 6.7 5.6 1.9 7.2 0.1 2.4 2 1 0 2 2 2 0 Otopetrin Reprolysin_4 PF13583.6 EMR71996.1 - 0.083 12.5 2.6 0.097 12.3 2.6 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like RNase_P_p30 PF01876.16 EMR71998.1 - 2e-51 174.5 0.0 3.7e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit p30 CPSF100_C PF13299.6 EMR71998.1 - 0.041 14.1 1.7 7.4 6.7 4.5 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Rtf2 PF04641.12 EMR71998.1 - 0.18 11.2 8.0 0.27 10.5 8.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Menin PF05053.13 EMR71998.1 - 6.1 5.1 13.2 10 4.3 13.2 1.3 1 0 0 1 1 1 0 Menin Pup PF05639.11 EMR71999.1 - 0.00087 20.1 0.7 0.00087 20.1 0.7 3.7 4 0 0 4 4 4 1 Pup-like protein RNA_pol_Rpb1_6 PF04992.14 EMR72000.1 - 0.056 13.3 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 RRM_1 PF00076.22 EMR72001.1 - 2.4e-74 245.1 0.2 1.8e-20 72.5 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMR72001.1 - 5.4e-10 39.0 0.0 0.2 11.5 0.0 5.0 5 0 0 5 5 5 3 Occluded RNA-recognition motif RRM_5 PF13893.6 EMR72001.1 - 1e-08 34.8 0.0 0.34 10.5 0.0 4.4 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMR72001.1 - 1.1e-08 34.9 0.1 0.004 17.1 0.0 2.9 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EMR72001.1 - 2.2e-08 34.1 0.9 0.71 10.0 0.0 6.1 6 1 0 6 6 6 3 Limkain b1 RRM_7 PF16367.5 EMR72001.1 - 1e-05 25.5 0.0 1.4 9.1 0.0 4.4 5 0 0 5 5 5 1 RNA recognition motif RRM_2 PF04059.12 EMR72001.1 - 1.7e-05 25.0 0.0 0.19 11.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif 2 RRM_3 PF08777.11 EMR72001.1 - 0.00038 20.4 0.1 1.5 9.0 0.0 4.4 4 0 0 4 4 4 1 RNA binding motif RRM_Rrp7 PF17799.1 EMR72001.1 - 0.0023 17.8 0.3 12 5.7 0.0 4.8 4 1 1 5 5 5 1 Rrp7 RRM-like N-terminal domain Ric8 PF10165.9 EMR72002.1 - 2.1e-66 224.9 0.4 1.4e-53 182.6 0.0 2.2 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn TAFII55_N PF04658.13 EMR72003.1 - 1.1e-41 142.2 0.0 2.1e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region CCDC32 PF14989.6 EMR72003.1 - 0.025 14.6 3.1 0.058 13.4 3.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing 32 GIT_CC PF16559.5 EMR72003.1 - 0.031 14.1 0.7 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cellulase PF00150.18 EMR72004.1 - 5.8e-40 137.5 0.2 8.9e-40 136.9 0.2 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.7 EMR72005.1 - 1.4e-12 48.0 0.6 8.6e-12 45.5 0.2 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMR72005.1 - 4.8e-12 45.9 0.6 6.9e-07 29.4 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMR72005.1 - 3e-10 40.4 0.2 0.0012 19.3 0.0 3.0 2 1 1 3 3 2 2 Ankyrin repeats (many copies) NACHT PF05729.12 EMR72005.1 - 2.4e-09 37.3 0.0 7.8e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 EMR72005.1 - 6.3e-08 32.7 0.0 0.0006 20.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EMR72005.1 - 1.1e-06 28.4 0.1 0.00055 20.2 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat AAA_22 PF13401.6 EMR72005.1 - 0.00057 20.2 0.0 0.0042 17.4 0.0 2.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EMR72005.1 - 0.0048 16.3 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EMR72005.1 - 0.0052 17.2 0.0 0.029 14.8 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EMR72005.1 - 0.023 15.1 0.0 0.076 13.4 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMR72005.1 - 0.024 15.2 0.2 0.6 10.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EMR72005.1 - 0.039 13.1 0.0 0.095 11.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 EMR72005.1 - 0.048 14.0 0.2 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain bZIP_1 PF00170.21 EMR72006.1 - 1.7e-05 24.8 10.2 1.7e-05 24.8 10.2 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EMR72006.1 - 1.4 9.1 13.1 10 6.3 12.4 2.2 1 1 0 1 1 1 0 Basic region leucine zipper 7tm_2 PF00002.24 EMR72007.1 - 1.8e-05 24.1 11.0 1.8e-05 24.1 11.0 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EMR72007.1 - 0.00063 19.0 3.3 0.00063 19.0 3.3 1.4 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor DC_STAMP PF07782.13 EMR72007.1 - 0.27 11.0 2.8 0.47 10.3 0.3 2.2 2 0 0 2 2 2 0 DC-STAMP-like protein SNF2_N PF00176.23 EMR72008.1 - 5.3e-27 94.5 0.8 9.3e-27 93.7 0.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMR72008.1 - 9.3e-13 48.5 0.0 1.9e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RSV_NS2 PF03113.14 EMR72008.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 Bromo_TP PF07524.13 EMR72009.1 - 1.7e-07 31.1 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated POTRA_TamA_1 PF17243.2 EMR72009.1 - 0.22 11.7 1.6 0.98 9.6 0.1 2.5 2 1 0 2 2 2 0 POTRA domain TamA domain 1 Glyco_hydro_15 PF00723.21 EMR72010.1 - 5.2e-52 177.1 0.0 8.7e-50 169.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 F-box PF00646.33 EMR72011.1 - 0.0085 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMR72011.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like Transket_pyr PF02779.24 EMR72012.1 - 6.2e-65 218.2 0.0 1.2e-64 217.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EMR72012.1 - 1.1e-57 195.3 0.0 1.5e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EMR72012.1 - 6.2e-56 188.3 0.0 1e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EMR72012.1 - 2e-19 68.9 1.4 4.3e-19 67.8 1.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus baeRF_family12 PF18856.1 EMR72012.1 - 0.039 14.5 0.1 0.13 12.9 0.1 1.9 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 Mito_carr PF00153.27 EMR72013.1 - 1.3e-40 137.2 13.1 8.2e-17 60.9 0.3 4.5 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMR72013.1 - 0.0052 16.0 2.6 0.087 12.0 0.2 2.4 3 0 0 3 3 3 2 Gammaproteobacterial serine protease WD40 PF00400.32 EMR72014.1 - 7e-25 86.8 20.4 8.1e-08 32.8 0.1 7.6 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR72014.1 - 2.6e-06 27.6 2.2 1.7 9.0 0.0 5.0 4 3 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR72014.1 - 0.0045 16.0 0.2 2.3 7.1 0.0 3.3 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5128 PF17170.4 EMR72014.1 - 0.28 10.3 0.0 0.41 9.7 0.0 1.2 1 0 0 1 1 1 0 6-bladed beta-propeller Coatomer_WDAD PF04053.14 EMR72014.1 - 0.41 9.6 2.8 4.5 6.2 0.4 2.1 2 0 0 2 2 2 0 Coatomer WD associated region ATP_bind_3 PF01171.20 EMR72016.1 - 3e-33 115.1 0.0 1e-21 77.5 0.0 2.3 1 1 0 2 2 2 2 PP-loop family DDHD PF02862.17 EMR72017.1 - 7.6e-23 81.8 0.0 8e-22 78.5 0.0 2.2 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.7 EMR72017.1 - 0.016 15.8 0.7 0.025 15.2 0.6 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 EMR72017.1 - 0.097 12.2 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF4097 PF13349.6 EMR72019.1 - 0.0016 17.8 0.5 0.66 9.3 0.2 2.9 2 1 1 3 3 3 3 Putative adhesin DUF3337 PF11816.8 EMR72020.1 - 1e-19 71.1 5.3 3.8e-11 43.1 0.0 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF3337) WD40 PF00400.32 EMR72020.1 - 7.6e-19 67.7 18.5 0.00031 21.5 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EMR72020.1 - 0.00055 18.7 1.1 0.0027 16.4 0.1 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EMR72020.1 - 0.00057 19.0 0.1 0.098 11.6 0.0 2.1 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EMR72020.1 - 0.031 14.6 1.3 0.45 10.8 0.1 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain GBP_C PF02841.14 EMR72020.1 - 0.084 12.3 8.1 0.13 11.6 8.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ANAPC4_WD40 PF12894.7 EMR72021.1 - 0.0018 18.5 0.0 0.11 12.8 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EMR72021.1 - 0.1 12.3 0.1 1 9.1 0.0 2.4 3 0 0 3 3 3 0 TUP1-like enhancer of split Cupin_8 PF13621.6 EMR72022.1 - 2.8e-31 109.2 0.0 3.3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EMR72022.1 - 1.6e-05 24.5 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein DAO PF01266.24 EMR72023.1 - 3.7e-53 181.3 0.0 5.7e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EMR72023.1 - 4e-44 149.5 0.1 6.8e-44 148.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EMR72023.1 - 2.6e-11 43.3 0.1 6.1e-11 42.0 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR72023.1 - 4.3e-05 22.9 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR72023.1 - 0.00013 21.4 4.5 0.0039 16.6 4.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMR72023.1 - 0.00029 20.2 0.0 0.033 13.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR72023.1 - 0.00065 19.0 0.4 0.0018 17.5 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR72023.1 - 0.0047 17.1 0.1 0.019 15.2 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR72023.1 - 0.014 14.6 0.3 0.035 13.3 0.1 1.7 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 EMR72023.1 - 0.02 14.8 0.2 0.039 13.9 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EMR72023.1 - 0.048 12.3 0.3 0.077 11.7 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.18 EMR72023.1 - 0.068 11.7 0.1 0.65 8.4 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox PF00070.27 EMR72023.1 - 0.12 12.9 1.6 0.21 12.2 0.6 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMR72023.1 - 0.13 11.3 0.1 0.67 9.0 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A DSPc PF00782.20 EMR72024.1 - 9.5e-26 90.2 0.0 3.1e-20 72.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMR72024.1 - 0.00015 21.4 0.2 0.0021 17.7 0.1 2.6 2 1 1 3 3 3 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EMR72024.1 - 0.065 13.3 0.0 0.25 11.4 0.1 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate BSD PF03909.17 EMR72025.1 - 2.9e-26 91.2 5.8 4.2e-13 49.1 0.4 3.3 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 EMR72025.1 - 2.3e-05 24.6 0.0 7.1e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Spermine_synth PF01564.17 EMR72025.1 - 0.02 14.3 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Atg14 PF10186.9 EMR72025.1 - 0.078 12.1 0.7 0.15 11.1 0.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MHYT PF03707.16 EMR72026.1 - 1.1e-19 70.4 13.5 1.1e-10 41.5 0.1 3.6 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat LapA_dom PF06305.11 EMR72026.1 - 0.42 10.5 0.1 0.42 10.5 0.1 3.5 2 1 2 4 4 4 0 Lipopolysaccharide assembly protein A domain YfhO PF09586.10 EMR72026.1 - 0.59 8.3 4.4 0.88 7.7 4.4 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4131 PF13567.6 EMR72026.1 - 1 9.0 7.1 0.9 9.2 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) p450 PF00067.22 EMR72028.1 - 1.7e-59 201.8 0.0 2.3e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.14 EMR72029.1 - 0.018 14.3 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR72029.1 - 0.096 12.9 0.1 0.16 12.2 0.1 1.5 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_3_C PF01915.22 EMR72031.1 - 9.8e-62 208.5 0.0 1.5e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMR72031.1 - 3e-47 161.6 0.0 4.8e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMR72031.1 - 2.4e-13 50.0 0.0 5.9e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EMR72031.1 - 1.4e-12 47.7 0.0 4.3e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 PA14 domain 4HBT_3 PF13622.6 EMR72032.1 - 5.7e-47 161.1 0.4 6.6e-47 160.9 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMR72032.1 - 2.8e-09 36.9 0.0 6.1e-06 26.1 0.0 2.8 2 1 1 3 3 3 2 Acyl-CoA thioesterase 4HBT PF03061.22 EMR72032.1 - 0.036 14.4 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Thioesterase superfamily p450 PF00067.22 EMR72033.1 - 3.2e-53 181.1 0.0 2e-31 109.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Beta_elim_lyase PF01212.21 EMR72035.1 - 9.7e-66 222.0 0.0 1.6e-65 221.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Trp_DMAT PF11991.8 EMR72035.1 - 1e-08 35.0 0.1 2.9e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase Esterase_phd PF10503.9 EMR72035.1 - 0.05 13.1 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF3632 PF12311.8 EMR72036.1 - 1.1e-25 91.1 0.0 1.4e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) 4HBT_3 PF13622.6 EMR72037.1 - 7.9e-26 91.8 0.2 9.1e-26 91.6 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMR72037.1 - 8.1e-09 35.4 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA thioesterase Methyltr_RsmB-F PF01189.17 EMR72038.1 - 6.8e-25 87.9 0.0 2e-24 86.3 0.0 1.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EMR72038.1 - 0.0011 19.1 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase APG5 PF04106.12 EMR72041.1 - 1.1e-46 159.2 0.0 3.4e-46 157.7 0.0 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 PNK3P PF08645.11 EMR72042.1 - 7.1e-33 113.6 0.0 8.6e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_like PF13242.6 EMR72042.1 - 0.014 15.4 0.0 0.04 14.0 0.0 1.9 1 1 1 2 2 2 0 HAD-hyrolase-like Pro_CA PF00484.19 EMR72043.1 - 3.7e-50 170.3 0.1 5e-50 169.8 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Thiolase_N PF00108.23 EMR72044.1 - 4.6e-66 222.8 2.8 5.8e-66 222.5 2.8 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMR72044.1 - 3.4e-40 136.5 0.1 9.9e-40 135.0 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF433 PF04255.14 EMR72044.1 - 0.13 12.1 0.0 4.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Glyco_hydro_cc PF11790.8 EMR72045.1 - 1.9e-70 237.1 0.1 2.3e-70 236.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.13 EMR72045.1 - 0.077 12.5 3.9 0.17 11.5 3.9 1.5 1 0 0 1 1 1 0 Fip1 motif Glyco_transf_90 PF05686.12 EMR72046.1 - 1.7e-23 83.2 1.0 2.7e-23 82.6 1.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 p450 PF00067.22 EMR72047.1 - 8.6e-45 153.3 0.0 1.2e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EMR72049.1 - 2.1e-09 36.8 0.0 3.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 EMR72050.1 - 1.2e-77 261.3 31.9 1e-42 146.7 16.4 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMR72050.1 - 3.1e-64 215.6 0.0 7.2e-31 107.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMR72050.1 - 1.1e-13 51.2 3.4 2.3e-06 27.2 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMR72050.1 - 8.3e-08 32.6 0.0 0.037 14.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMR72050.1 - 6.4e-07 29.0 0.1 0.014 15.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EMR72050.1 - 2.1e-06 28.2 0.0 0.021 15.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMR72050.1 - 3.6e-06 27.0 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 EMR72050.1 - 6.2e-06 25.3 0.8 0.18 10.6 0.1 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 EMR72050.1 - 6.3e-06 26.1 0.0 0.063 13.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EMR72050.1 - 6.4e-06 25.6 0.1 0.22 10.8 0.0 3.6 4 0 0 4 4 4 2 Zeta toxin AAA_21 PF13304.6 EMR72050.1 - 6.8e-06 26.1 0.0 0.3 10.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EMR72050.1 - 3.4e-05 23.5 0.1 0.13 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EMR72050.1 - 0.00031 20.5 0.2 0.85 9.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 EMR72050.1 - 0.0017 18.6 0.1 0.78 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMR72050.1 - 0.002 18.1 0.0 3.7 7.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EMR72050.1 - 0.0025 18.0 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EMR72050.1 - 0.0033 17.9 0.1 7.7 7.0 0.0 3.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EMR72050.1 - 0.0073 16.8 0.0 3.3 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMR72050.1 - 0.0074 16.8 0.0 4.6 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 EMR72050.1 - 0.012 14.8 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EMR72050.1 - 0.012 15.1 0.0 5.5 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EMR72050.1 - 0.027 14.7 6.3 2.6 8.3 0.2 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 EMR72050.1 - 0.035 14.1 0.0 7.1 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 EMR72050.1 - 0.039 13.6 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 EMR72050.1 - 0.043 13.7 0.0 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MtrB PF05440.12 EMR72050.1 - 0.073 13.5 0.0 0.97 9.9 0.0 2.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B MMR_HSR1 PF01926.23 EMR72050.1 - 0.073 13.2 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EMR72050.1 - 0.079 13.4 0.1 4.9 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 EMR72050.1 - 0.096 12.8 0.1 15 5.6 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Ploopntkinase3 PF18751.1 EMR72050.1 - 0.13 12.2 0.0 27 4.6 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RepB-RCR_reg PF10723.9 EMR72050.1 - 0.15 12.0 0.0 17 5.4 0.0 2.7 2 0 0 2 2 2 0 Replication regulatory protein RepB PRK PF00485.18 EMR72050.1 - 0.16 11.7 0.1 18 5.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 EMR72050.1 - 0.2 11.5 0.0 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain 60KD_IMP PF02096.20 EMR72050.1 - 0.61 10.0 7.7 0.21 11.5 0.7 2.6 2 0 0 2 2 2 0 60Kd inner membrane protein ABC_tran PF00005.27 EMR72051.1 - 3.1e-50 170.3 0.1 1.2e-26 93.8 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMR72051.1 - 1.1e-13 51.7 5.6 0.0031 17.4 0.0 4.5 3 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMR72051.1 - 1.8e-12 47.2 0.0 0.0022 17.4 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMR72051.1 - 5.5e-09 36.8 0.5 0.00053 20.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EMR72051.1 - 6.4e-07 29.4 0.0 0.0089 16.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EMR72051.1 - 1.4e-06 28.0 0.8 0.017 14.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMR72051.1 - 7.5e-06 26.0 1.9 0.04 13.8 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase Chromo PF00385.24 EMR72051.1 - 5.3e-05 23.0 2.1 0.00016 21.5 2.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.6 EMR72051.1 - 0.00017 21.9 0.0 0.83 9.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EMR72051.1 - 0.00029 21.4 0.2 0.6 10.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EMR72051.1 - 0.00045 20.1 0.8 0.33 10.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 EMR72051.1 - 0.0011 19.1 0.1 0.27 11.3 0.0 3.0 2 1 0 2 2 2 1 Dynamin family SbcCD_C PF13558.6 EMR72051.1 - 0.0016 18.6 0.1 1.3 9.3 0.0 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 EMR72051.1 - 0.0033 16.4 0.2 1.1 8.2 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EMR72051.1 - 0.0034 17.5 1.0 0.46 10.6 0.0 3.2 3 0 0 3 3 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 EMR72051.1 - 0.0034 17.8 0.1 3.1 8.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 EMR72051.1 - 0.0036 17.5 0.0 2.2 8.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EMR72051.1 - 0.0058 16.4 0.0 0.93 9.2 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SR-25 PF10500.9 EMR72051.1 - 0.013 15.1 4.4 0.025 14.2 4.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_28 PF13521.6 EMR72051.1 - 0.013 15.7 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMR72051.1 - 0.023 14.6 0.4 6.8 6.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EMR72051.1 - 0.023 14.4 1.7 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMR72051.1 - 0.024 14.3 0.4 4.4 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMR72051.1 - 0.035 14.5 0.1 5.7 7.4 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EMR72051.1 - 0.07 12.7 1.7 8.4 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EMR72051.1 - 0.089 13.2 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 EMR72051.1 - 0.1 11.8 0.2 3.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EMR72051.1 - 0.14 12.0 0.4 20 5.0 0.2 2.8 3 0 0 3 3 3 0 NTPase AAA_13 PF13166.6 EMR72051.1 - 0.15 10.7 0.8 8.9 4.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain RRM_1 PF00076.22 EMR72052.1 - 1.9e-07 30.8 0.0 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EMR72052.1 - 0.016 15.2 0.1 0.22 11.5 0.1 2.2 1 1 0 1 1 1 0 DbpA RNA binding domain Coilin_N PF15862.5 EMR72052.1 - 0.054 13.3 10.2 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 Coilin N-terminus ubiquitin PF00240.23 EMR72052.1 - 0.094 12.5 0.2 3.9 7.3 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin family RRM_occluded PF16842.5 EMR72052.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif SpoIIIAH PF12685.7 EMR72052.1 - 0.14 11.9 4.3 0.94 9.3 0.1 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Mob_synth_C PF06463.13 EMR72053.1 - 1.5e-38 131.6 0.1 1.9e-37 128.1 0.0 2.2 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EMR72053.1 - 2.4e-27 96.3 0.0 4.3e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EMR72053.1 - 4.7e-06 26.9 0.0 4.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMR72053.1 - 0.013 15.6 0.0 0.056 13.6 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain DS PF01916.17 EMR72054.1 - 1.5e-132 441.2 0.0 1.8e-132 441.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase ABM PF03992.16 EMR72055.1 - 1.2e-07 31.8 2.8 0.002 18.2 0.3 2.6 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 EMR72055.1 - 0.00028 21.2 0.7 0.0041 17.4 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1330) DAG1 PF05454.11 EMR72056.1 - 1.1 8.6 10.1 0.3 10.4 6.9 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PAN_4 PF14295.6 EMR72058.1 - 0.017 15.0 3.1 0.075 13.0 1.3 2.7 2 0 0 2 2 2 0 PAN domain Jnk-SapK_ap_N PF09744.9 EMR72059.1 - 0.011 16.0 10.2 0.011 16.0 10.2 1.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 EMR72059.1 - 0.047 14.0 4.0 0.19 12.1 0.7 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC92 PF14916.6 EMR72059.1 - 0.053 13.3 0.3 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function FCD PF07729.12 EMR72059.1 - 0.52 10.7 5.2 4.7 7.6 0.5 2.8 2 1 0 2 2 2 0 FCD domain Spt20 PF12090.8 EMR72062.1 - 0.022 14.4 5.5 0.043 13.4 5.5 1.4 1 0 0 1 1 1 0 Spt20 family DUF3484 PF11983.8 EMR72062.1 - 8.4 7.6 10.9 3.8 8.7 3.7 2.8 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Methyltransf_2 PF00891.18 EMR72066.1 - 1.1e-23 83.7 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HTH_AsnC-type PF13404.6 EMR72066.1 - 0.00059 19.6 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EMR72066.1 - 0.041 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 EMR72066.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Pro_isomerase PF00160.21 EMR72067.1 - 6.3e-42 143.5 0.0 2.1e-41 141.8 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 EMR72067.1 - 0.0054 17.2 0.2 0.0054 17.2 0.2 4.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) Hira PF07569.11 EMR72068.1 - 0.00069 19.4 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 2 TUP1-like enhancer of split Nbas_N PF15492.6 EMR72068.1 - 0.0078 15.6 0.3 0.84 8.9 0.1 3.1 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 EMR72068.1 - 0.047 14.0 0.0 1.2 9.5 0.0 2.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMR72068.1 - 0.18 12.7 0.5 84 4.3 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat HSF_DNA-bind PF00447.17 EMR72069.1 - 2.8e-28 98.4 0.6 6e-28 97.3 0.6 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.8 EMR72069.1 - 0.049 13.6 2.4 6.8 6.8 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EMR72069.1 - 0.056 13.7 10.1 0.34 11.1 0.2 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Ets PF00178.22 EMR72069.1 - 0.12 12.8 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 Ets-domain XhlA PF10779.9 EMR72069.1 - 0.3 11.3 6.4 0.46 10.7 0.3 3.1 3 1 0 3 3 3 0 Haemolysin XhlA SPAM PF02090.15 EMR72069.1 - 1.3 8.8 8.0 0.5 10.2 0.8 2.5 3 0 0 3 3 3 0 Salmonella surface presentation of antigen gene type M protein Mod_r PF07200.13 EMR72069.1 - 2.8 8.0 9.1 2.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HIP1_clath_bdg PF16515.5 EMR72069.1 - 3.4 8.4 10.3 3.3 8.4 1.0 3.6 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 EMR72069.1 - 3.9 7.7 6.4 13 5.9 0.1 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 EMR72069.1 - 4 6.4 6.5 14 4.7 0.0 3.0 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 EMR72069.1 - 6.6 6.8 7.4 4.4 7.3 3.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_4 PF12799.7 EMR72070.1 - 5.6e-31 106.1 33.1 1.9e-05 24.9 0.3 9.6 5 1 5 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMR72070.1 - 5e-21 74.2 41.8 5.3e-06 26.1 3.8 7.3 6 2 2 8 8 8 5 Leucine rich repeat LRR_9 PF14580.6 EMR72070.1 - 8.9e-09 35.1 11.4 0.0054 16.3 0.1 4.8 2 2 3 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 EMR72070.1 - 6.1e-07 29.0 22.6 0.82 9.9 0.1 9.7 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.33 EMR72070.1 - 0.01 16.3 29.8 15 6.6 0.3 10.7 9 4 0 9 9 9 0 Leucine Rich Repeat Beta_helix PF13229.6 EMR72070.1 - 0.086 12.7 0.4 0.35 10.7 0.4 1.9 1 1 0 1 1 1 0 Right handed beta helix region Apc15p PF05841.11 EMR72070.1 - 0.088 13.6 2.3 13 6.6 0.1 2.4 2 0 0 2 2 2 0 Apc15p protein NosD PF05048.13 EMR72070.1 - 0.14 11.4 0.9 0.37 10.0 0.9 1.7 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Toprim_2 PF13155.6 EMR72070.1 - 0.22 12.0 1.2 6.5 7.3 0.2 2.8 3 0 0 3 3 3 0 Toprim-like SUIM_assoc PF16619.5 EMR72070.1 - 5.1 7.2 9.6 1.5 8.9 4.7 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 EMR72071.1 - 4.7e-08 33.0 0.0 8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMR72071.1 - 5.5e-07 29.9 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMR72071.1 - 0.0013 18.7 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Gly_transf_sug PF04488.15 EMR72072.1 - 1.5e-13 51.1 0.0 3.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EMR72072.1 - 0.049 12.9 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain RRM_1 PF00076.22 EMR72073.1 - 1.4e-43 146.6 0.5 1.4e-20 72.9 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EMR72073.1 - 7.7e-23 81.4 0.1 2.5e-22 79.7 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EMR72073.1 - 5.9e-05 22.8 0.0 0.11 12.3 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EMR72073.1 - 0.00038 20.5 0.2 0.019 15.0 0.0 2.9 2 1 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 EMR72073.1 - 0.011 15.3 0.0 0.041 13.5 0.0 2.0 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR72073.1 - 0.03 14.4 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DUF4078 PF13300.6 EMR72073.1 - 0.093 13.1 2.1 9.7 6.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4078) Peptidase_M28 PF04389.17 EMR72075.1 - 2.3e-38 131.9 0.1 3.4e-38 131.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMR72075.1 - 1e-14 54.3 1.5 2.7e-14 53.0 1.5 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EMR72075.1 - 4.6e-05 23.2 0.1 0.0004 20.1 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Hexapep PF00132.24 EMR72077.1 - 2.3e-08 33.5 15.8 1.9e-05 24.2 5.6 3.7 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EMR72077.1 - 0.00011 20.5 1.1 0.00018 19.8 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 EMR72077.1 - 0.00022 20.9 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 EMR72077.1 - 0.00022 20.3 2.0 0.096 11.6 0.3 2.2 1 1 1 2 2 2 2 L-fucokinase NTP_transf_3 PF12804.7 EMR72077.1 - 0.0072 16.7 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EMR72077.1 - 0.031 14.0 7.3 0.38 10.5 2.3 2.8 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase TPP_enzyme_N PF02776.18 EMR72077.1 - 0.093 12.3 0.9 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Septin PF00735.18 EMR72078.1 - 7.4e-33 114.0 0.0 1e-10 41.4 0.0 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 EMR72078.1 - 0.00059 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.6 EMR72078.1 - 0.0052 17.3 0.1 0.016 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 EMR72078.1 - 0.0059 15.8 0.0 0.019 14.1 0.0 1.7 1 1 0 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 EMR72078.1 - 0.0088 16.4 0.6 0.02 15.3 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EMR72078.1 - 0.014 15.9 0.1 0.093 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.12 EMR72078.1 - 0.017 13.4 7.7 0.022 13.0 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_A32 PF04665.12 EMR72078.1 - 0.022 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein KAP_NTPase PF07693.14 EMR72078.1 - 0.053 12.7 0.0 0.063 12.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 EMR72078.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 EMR72078.1 - 0.11 12.2 0.0 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 EMR72078.1 - 0.12 12.5 1.6 0.75 9.8 0.1 2.4 2 1 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 EMR72078.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 EMR72078.1 - 0.45 8.7 6.4 0.63 8.3 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EMR72078.1 - 0.54 9.6 9.4 0.78 9.1 9.4 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EMR72078.1 - 1.1 8.5 5.4 1.7 7.9 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIE-A_C PF11521.8 EMR72078.1 - 3.1 8.2 12.9 7.7 6.9 12.9 1.7 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DNA_pol_B PF00136.21 EMR72079.1 - 6.4e-95 318.5 0.0 4.5e-94 315.7 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 EMR72079.1 - 7.1e-15 55.2 2.6 7.4e-15 55.2 0.5 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EMR72079.1 - 0.11 11.4 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Ribosomal_L21e PF01157.18 EMR72080.1 - 1.1e-46 156.9 5.1 1.1e-46 156.9 5.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e SH3_15 PF18346.1 EMR72080.1 - 1.1 9.6 3.3 8 6.9 3.3 2.4 1 1 0 1 1 1 0 Mind bomb SH3 repeat domain COX6A PF02046.15 EMR72081.1 - 8.7e-54 180.8 0.9 1.1e-53 180.5 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa CIA30 PF08547.12 EMR72082.1 - 5.7e-44 149.9 0.0 8.1e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Tudor_2 PF18104.1 EMR72082.1 - 0.13 12.0 0.1 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Ferric_reduct PF01794.19 EMR72083.1 - 2.8e-22 79.1 8.9 2.8e-22 79.1 8.9 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMR72083.1 - 1.8e-19 70.4 0.0 1.1e-11 45.1 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR72083.1 - 9.9e-08 32.0 0.0 1e-05 25.5 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain DUF485 PF04341.12 EMR72083.1 - 0.6 10.1 10.4 8.6 6.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF485 ANAPC5 PF12862.7 EMR72084.1 - 1.1e-33 115.1 5.1 1.1e-33 115.1 5.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EMR72084.1 - 1.5e-06 28.4 17.5 0.03 14.6 0.2 5.9 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EMR72084.1 - 0.0059 16.4 1.3 1.8 8.5 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMR72084.1 - 0.079 12.8 1.4 76 3.4 0.4 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR72084.1 - 0.29 11.9 19.6 50 4.9 0.1 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMR72084.1 - 6.7 7.3 19.2 7.9 7.1 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat zf-GRF PF06839.12 EMR72085.1 - 5.7e-07 29.5 5.0 1.2e-06 28.5 5.0 1.6 1 1 0 1 1 1 1 GRF zinc finger ABC1 PF03109.16 EMR72086.1 - 3.3e-23 82.1 0.0 6.6e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EMR72086.1 - 3.1e-05 24.0 0.0 7.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family YpsA PF06908.11 EMR72086.1 - 0.22 11.5 0.6 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 YspA SLOG family ANTH PF07651.16 EMR72087.1 - 8.4e-82 274.3 0.0 8.4e-82 274.3 0.0 2.4 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.17 EMR72087.1 - 8.6e-53 178.7 7.8 8.6e-53 178.7 7.8 6.3 5 2 2 7 7 7 2 I/LWEQ domain Slu7 PF11708.8 EMR72088.1 - 2.2e-76 257.2 18.7 2.2e-76 257.2 18.7 2.6 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EMR72088.1 - 0.041 13.6 0.5 0.072 12.8 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 EMR72089.1 - 2.4e-12 46.4 0.9 2.4e-12 46.4 0.9 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EMR72089.1 - 8.6e-06 26.6 0.1 1.7e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 EMR72089.1 - 0.073 13.2 0.4 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation MMM1 PF10296.9 EMR72090.1 - 7.7e-07 28.5 0.7 2.2e-05 23.7 0.0 2.5 3 0 0 3 3 3 2 Maintenance of mitochondrial morphology protein 1 SF1-HH PF16275.5 EMR72091.1 - 0.04 14.2 0.1 0.1 12.9 0.1 1.8 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain DPM3 PF08285.11 EMR72091.1 - 0.72 10.1 2.3 2.7 8.2 0.1 2.6 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pal1 PF08316.11 EMR72092.1 - 1.3e-47 162.0 2.5 1.7e-47 161.7 0.9 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein FAD_binding_4 PF01565.23 EMR72093.1 - 6.8e-18 64.7 2.8 9.6e-18 64.3 2.8 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EMR72093.1 - 1.8e-09 37.8 1.7 3e-08 33.8 1.7 2.0 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase DUF3403 PF11883.8 EMR72094.1 - 0.12 12.5 3.5 0.42 10.8 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) RIFIN PF02009.16 EMR72094.1 - 6.7 6.5 5.7 9.7 6.0 5.7 1.4 1 1 0 1 1 1 0 Rifin Methyltransf_23 PF13489.6 EMR72095.1 - 1.5e-10 41.1 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR72095.1 - 3.4e-07 30.2 0.0 4.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR72095.1 - 3e-05 24.6 0.0 5.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR72095.1 - 0.00014 22.5 0.0 0.00029 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR72095.1 - 0.00014 22.5 0.0 0.00023 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EMR72095.1 - 0.0015 18.0 0.0 0.0047 16.4 0.0 1.7 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain zinc_ribbon_5 PF13719.6 EMR72096.1 - 0.13 12.0 0.3 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Fungal_trans PF04082.18 EMR72097.1 - 5.8e-06 25.5 0.1 1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR72097.1 - 0.053 13.7 1.7 0.094 12.9 1.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 EMR72098.1 - 8e-11 42.5 9.5 8.7e-09 35.9 1.6 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 EMR72099.1 - 9e-24 83.8 4.9 1.5e-23 83.1 4.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR72099.1 - 2.6e-10 40.2 0.0 4.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Pept_S41_N PF18294.1 EMR72099.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain MMtag PF10159.9 EMR72100.1 - 1.4e-31 108.6 2.2 1.4e-31 108.6 2.2 1.7 2 0 0 2 2 2 1 Multiple myeloma tumor-associated FRQ PF09421.10 EMR72100.1 - 0.071 11.1 1.2 0.085 10.9 1.2 1.0 1 0 0 1 1 1 0 Frequency clock protein U1snRNP70_N PF12220.8 EMR72100.1 - 0.096 13.3 0.8 0.17 12.5 0.8 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4217 PF13959.6 EMR72100.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) Androgen_recep PF02166.16 EMR72100.1 - 0.24 10.2 12.5 0.41 9.4 12.5 1.3 1 0 0 1 1 1 0 Androgen receptor MFS_1 PF07690.16 EMR72101.1 - 2.7e-31 108.8 59.8 2.3e-27 95.9 43.4 2.8 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR72101.1 - 3.4e-14 52.6 9.7 8.4e-14 51.3 9.7 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter MMR_HSR1_Xtn PF16897.5 EMR72102.1 - 1.4e-33 115.1 1.4 1.8e-32 111.5 0.3 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EMR72102.1 - 2.2e-20 72.8 0.0 5.5e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EMR72102.1 - 3.1e-20 72.0 0.1 5.9e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EMR72102.1 - 2.9e-12 46.4 0.0 4.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EMR72102.1 - 0.00017 21.7 0.2 0.13 12.3 0.0 2.6 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EMR72102.1 - 0.083 11.9 0.1 0.17 10.9 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 EMR72102.1 - 0.11 11.6 0.0 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain ATP_bind_1 PF03029.17 EMR72102.1 - 0.28 10.9 1.4 9.9 5.9 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Lactonase PF10282.9 EMR72104.1 - 2.3e-66 224.4 0.0 2.9e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.6 EMR72104.1 - 0.0027 17.3 0.5 0.0043 16.7 0.5 1.3 1 0 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 EMR72104.1 - 0.068 13.1 0.9 0.2 11.6 0.3 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat Myosin_tail_1 PF01576.19 EMR72105.1 - 0.099 10.4 0.2 0.13 10.1 0.2 1.0 1 0 0 1 1 1 0 Myosin tail UreF PF01730.16 EMR72106.1 - 2.3e-21 76.7 0.3 8.5e-20 71.7 0.3 2.4 1 1 0 1 1 1 1 UreF CENP-B_dimeris PF09026.10 EMR72106.1 - 0.0012 19.2 1.3 0.0012 19.2 1.3 3.1 3 0 0 3 3 3 1 Centromere protein B dimerisation domain SUIM_assoc PF16619.5 EMR72106.1 - 0.016 15.3 3.2 0.034 14.2 3.2 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3246 PF11596.8 EMR72106.1 - 0.15 11.4 0.8 0.29 10.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Mito_fiss_reg PF05308.11 EMR72106.1 - 5.6 7.0 11.2 12 5.9 11.2 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3824 PF12868.7 EMR72106.1 - 7.3 7.2 18.3 6.3 7.5 4.6 2.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DLH PF01738.18 EMR72107.1 - 1.4e-13 50.9 0.0 1.9e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF3684 PF12449.8 EMR72108.1 - 0 1489.6 0.0 0 1489.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EMR72108.1 - 7.6e-05 22.6 0.0 0.00021 21.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K_channel_TID PF07941.11 EMR72108.1 - 0.89 10.1 6.3 3.8 8.0 6.3 2.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain LOR PF04525.12 EMR72109.1 - 6.6e-07 29.1 0.3 1.2e-06 28.2 0.3 1.5 1 1 0 1 1 1 1 LURP-one-related VASt PF16016.5 EMR72109.1 - 0.076 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain Sugar_tr PF00083.24 EMR72110.1 - 1.6e-47 162.4 10.2 8.4e-35 120.5 0.3 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR72110.1 - 4.1e-07 29.2 19.2 0.0039 16.2 9.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Voldacs PF03517.13 EMR72111.1 - 8.2e-23 81.1 0.2 8.2e-23 81.1 0.2 1.7 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling BBE PF08031.12 EMR72112.1 - 0.046 13.8 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like ADH_zinc_N PF00107.26 EMR72113.1 - 2e-08 34.3 0.0 8.2e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR72113.1 - 5.9e-07 29.3 0.0 0.00011 22.1 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain tRNA-synt_1e PF01406.19 EMR72114.1 - 2e-75 253.9 0.0 2e-75 253.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 EMR72114.1 - 0.012 16.1 1.4 0.046 14.2 0.0 2.6 2 0 0 2 2 2 0 DALR domain ATP11 PF06644.11 EMR72114.1 - 3.5 7.4 16.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 ATP11 protein PGA2 PF07543.12 EMR72114.1 - 5.4 7.0 13.4 18 5.3 13.4 1.9 1 0 0 1 1 1 0 Protein trafficking PGA2 AMP-binding PF00501.28 EMR72115.1 - 2.5e-69 233.9 0.3 1e-44 152.9 0.6 2.3 1 1 1 2 2 2 2 AMP-binding enzyme KR PF08659.10 EMR72115.1 - 2.2e-45 154.8 0.2 3.2e-41 141.2 0.0 2.5 2 0 0 2 2 2 2 KR domain NAD_binding_4 PF07993.12 EMR72115.1 - 5.9e-39 133.8 0.0 1.1e-38 132.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 EMR72115.1 - 1.7e-32 112.7 0.0 2.6e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EMR72115.1 - 1.7e-16 60.3 0.0 5.4e-10 39.5 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 EMR72115.1 - 2.6e-12 46.6 1.5 2e-08 33.9 0.0 3.3 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.21 EMR72115.1 - 2.9e-11 43.3 0.0 9.8e-11 41.6 0.0 1.9 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMR72115.1 - 3.6e-08 32.8 0.0 9.6e-08 31.4 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 EMR72115.1 - 5.3e-05 22.9 0.2 0.001 18.7 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase AMP-binding_C PF13193.6 EMR72115.1 - 0.0003 21.7 0.0 0.0015 19.5 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NmrA PF05368.13 EMR72115.1 - 0.008 15.8 0.1 0.02 14.4 0.1 1.7 1 0 0 1 1 1 1 NmrA-like family MFS_1 PF07690.16 EMR72116.1 - 4.3e-35 121.3 56.8 6.2e-34 117.5 56.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR72116.1 - 2.5e-18 65.8 19.5 3.9e-18 65.2 19.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMR72116.1 - 0.0025 16.2 10.9 0.014 13.7 3.1 2.5 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family GCD14 PF08704.10 EMR72117.1 - 0.00012 21.9 1.2 0.0013 18.5 0.1 2.4 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PS-DH PF14765.6 EMR72118.1 - 3.1e-44 151.4 0.0 4.6e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EMR72118.1 - 3.7e-41 141.7 0.0 5.9e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EMR72118.1 - 2.2e-37 129.0 0.0 1.9e-26 93.2 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMR72118.1 - 5.1e-32 110.4 0.0 1.5e-31 108.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Cut12 PF11500.8 EMR72119.1 - 1e-46 158.5 15.5 1e-46 158.5 15.5 4.7 3 1 1 4 4 4 1 Spindle pole body formation-associated protein DUF4200 PF13863.6 EMR72119.1 - 0.00032 21.1 12.7 0.00032 21.1 12.7 4.5 3 1 2 5 5 5 1 Domain of unknown function (DUF4200) FlxA PF14282.6 EMR72119.1 - 0.0016 18.4 5.8 0.0016 18.4 5.8 4.7 3 1 1 4 4 4 1 FlxA-like protein BST2 PF16716.5 EMR72119.1 - 0.0031 18.0 4.0 0.0031 18.0 4.0 4.6 3 1 2 5 5 5 1 Bone marrow stromal antigen 2 DUF1216 PF06746.11 EMR72119.1 - 0.2 11.6 14.9 0.12 12.4 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1216) LPP PF04728.13 EMR72119.1 - 0.5 10.8 12.2 4.5 7.7 0.3 4.6 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Bacillus_HBL PF05791.11 EMR72119.1 - 1.3 8.8 20.0 0.13 12.1 5.8 2.9 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2730 PF10805.8 EMR72119.1 - 6.5 6.9 17.1 0.062 13.4 1.9 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) DUF3759 PF12585.8 EMR72120.1 - 1e-40 137.6 4.5 1.2e-40 137.4 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 EMR72120.1 - 0.24 12.0 2.8 1.5 9.5 2.8 2.0 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Acyl-CoA_dh_1 PF00441.24 EMR72121.1 - 3.6e-29 101.9 0.4 6e-29 101.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMR72121.1 - 5.5e-21 74.6 0.0 1.1e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMR72121.1 - 3.7e-14 53.3 0.0 7.7e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMR72121.1 - 1.4e-13 51.3 0.8 2.7e-13 50.3 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAF-AH_p_II PF03403.13 EMR72122.1 - 7.6e-40 136.6 0.0 8.4e-35 120.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EMR72122.1 - 0.00014 20.9 0.0 0.00031 19.7 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EMR72122.1 - 0.00094 18.5 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EMR72122.1 - 0.0072 15.4 0.0 0.024 13.7 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase Pkinase PF00069.25 EMR72123.1 - 3.3e-26 92.2 0.0 3.4e-25 88.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR72123.1 - 2.7e-13 49.8 0.0 6.7e-09 35.4 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EMR72123.1 - 0.042 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_I PF03899.15 EMR72124.1 - 0.2 12.1 4.1 0.068 13.5 1.2 1.9 2 1 0 2 2 2 0 ATP synthase I chain EthD PF07110.11 EMR72125.1 - 6.6e-05 24.0 0.1 0.0001 23.4 0.1 1.4 1 0 0 1 1 1 1 EthD domain LSM PF01423.22 EMR72126.1 - 2.1e-16 59.4 0.2 2.7e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain Abhydrolase_6 PF12697.7 EMR72127.1 - 4e-06 27.6 0.8 5.5e-06 27.2 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 EMR72127.1 - 5.7e-05 21.9 0.1 0.001 17.8 0.0 2.3 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EMR72127.1 - 0.00085 18.9 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EMR72127.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M18 PF02127.15 EMR72128.1 - 8.6e-129 430.1 0.0 1e-128 429.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) p450 PF00067.22 EMR72130.1 - 2.8e-64 217.6 0.0 3.3e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HGTP_anticodon2 PF12745.7 EMR72131.1 - 5.2e-69 232.7 20.9 2.2e-38 132.3 0.1 3.6 2 1 1 3 3 3 2 Anticodon binding domain of tRNAs Pkinase PF00069.25 EMR72131.1 - 1.7e-36 126.0 6.1 5.9e-21 75.0 0.0 4.0 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR72131.1 - 1.5e-18 67.0 0.1 4.4e-08 32.7 0.0 3.4 3 0 0 3 3 3 2 Protein tyrosine kinase RWD PF05773.22 EMR72131.1 - 7.6e-13 48.8 0.0 4.1e-12 46.4 0.0 2.4 1 0 0 1 1 1 1 RWD domain Pkinase_fungal PF17667.1 EMR72131.1 - 0.0075 15.1 5.5 0.44 9.2 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EMR72131.1 - 0.02 14.8 0.1 0.02 14.8 0.1 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DDHD PF02862.17 EMR72131.1 - 0.033 14.4 5.0 0.72 10.0 1.9 2.4 2 0 0 2 2 2 0 DDHD domain YABBY PF04690.13 EMR72131.1 - 0.096 13.2 5.5 0.25 11.9 5.5 1.6 1 0 0 1 1 1 0 YABBY protein Presenilin PF01080.17 EMR72131.1 - 0.63 8.8 8.8 1 8.1 5.5 2.0 2 0 0 2 2 2 0 Presenilin FTA2 PF13095.6 EMR72131.1 - 0.89 9.1 6.4 1.5 8.4 0.0 3.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 PA26 PF04636.13 EMR72131.1 - 6.3 5.6 6.5 15 4.4 6.5 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Torus PF16131.5 EMR72132.1 - 5.3e-45 152.6 0.5 1.2e-44 151.4 0.0 1.9 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EMR72132.1 - 4e-08 33.0 0.0 9.3e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EMR72132.1 - 0.00024 21.0 0.6 0.00024 21.0 0.6 1.9 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 EMR72132.1 - 0.0011 18.8 0.9 0.0019 18.1 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 EMR72132.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 EMR72132.1 - 0.71 9.7 6.0 0.16 11.8 2.6 1.7 2 0 0 2 2 2 0 CCCH-type zinc finger Spo12 PF05032.12 EMR72133.1 - 1.8e-15 56.5 0.3 4.6e-15 55.2 0.3 1.8 1 0 0 1 1 1 1 Spo12 family CENP-R PF06729.12 EMR72133.1 - 0.043 13.7 1.8 0.046 13.7 1.3 1.4 1 1 0 1 1 1 0 Kinetochore component, CENP-R Glyco_hydro_26 PF02156.15 EMR72134.1 - 2.2e-82 277.0 6.6 2.7e-82 276.7 6.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 EMR72134.1 - 7.9e-31 106.8 0.6 1.5e-30 105.9 0.6 1.5 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) DUF2436 PF10365.9 EMR72134.1 - 0.028 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) POTRA_3 PF17287.2 EMR72134.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 POTRA domain Aldo_ket_red PF00248.21 EMR72135.1 - 8e-51 173.0 0.0 1.4e-48 165.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Death PF00531.22 EMR72135.1 - 0.00062 19.9 0.0 1 9.6 0.0 3.4 3 0 0 3 3 3 2 Death domain Glyco_hydro_18 PF00704.28 EMR72136.1 - 1.3e-11 44.8 0.0 3.4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 HEAT_EZ PF13513.6 EMR72137.1 - 1.3e-20 73.5 6.6 8.7e-07 29.3 0.8 8.8 8 1 1 9 9 8 3 HEAT-like repeat HEAT PF02985.22 EMR72137.1 - 8.2e-17 59.9 9.9 0.00062 19.8 0.1 8.8 10 0 0 10 10 7 3 HEAT repeat HEAT_2 PF13646.6 EMR72137.1 - 1.5e-15 57.3 12.9 0.0014 18.9 0.0 8.3 6 2 1 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EMR72137.1 - 6.8e-10 39.4 0.0 0.029 15.0 0.0 5.7 5 1 1 6 6 5 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 EMR72137.1 - 7.9e-09 35.3 0.0 5.4e-07 29.4 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.12 EMR72137.1 - 4.9e-07 29.7 0.1 0.15 11.8 0.0 4.5 4 1 0 5 5 4 2 rRNA processing/ribosome biogenesis DRIM PF07539.12 EMR72137.1 - 8e-06 24.4 0.3 0.15 10.4 0.0 3.9 2 2 1 4 4 4 2 Down-regulated in metastasis IFRD PF05004.13 EMR72137.1 - 8.7e-06 25.1 0.2 0.79 8.8 0.0 4.7 2 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) UME PF08064.13 EMR72137.1 - 1.3e-05 25.1 0.0 0.49 10.3 0.0 5.8 6 1 0 6 6 6 1 UME (NUC010) domain Adaptin_N PF01602.20 EMR72137.1 - 2e-05 23.4 0.3 1.4 7.4 0.0 4.8 3 1 0 4 4 4 1 Adaptin N terminal region Arm PF00514.23 EMR72137.1 - 3.5e-05 23.7 6.8 1.5 9.0 0.0 6.7 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat ParcG PF10274.9 EMR72137.1 - 0.00013 22.2 0.6 0.18 11.9 0.1 4.6 3 2 2 5 5 5 1 Parkin co-regulated protein RTP1_C1 PF10363.9 EMR72137.1 - 0.001 19.2 0.9 0.74 10.0 0.1 5.0 6 1 0 6 6 5 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 EMR72137.1 - 0.002 18.2 0.1 6.6 6.9 0.0 3.8 4 0 0 4 4 3 1 V-ATPase subunit H BLM10_mid PF16507.5 EMR72137.1 - 0.011 14.4 0.5 0.55 8.8 0.0 2.7 3 0 0 3 3 3 0 Proteasome-substrate-size regulator, mid region V-ATPase_H_N PF03224.14 EMR72137.1 - 0.016 14.5 0.7 1.2 8.4 0.4 2.8 2 0 0 2 2 2 0 V-ATPase subunit H Vitellogenin_N PF01347.22 EMR72137.1 - 0.016 13.6 0.5 0.062 11.7 0.1 2.2 3 1 0 3 3 3 0 Lipoprotein amino terminal region BP28CT PF08146.12 EMR72137.1 - 0.055 13.3 0.0 10 5.9 0.0 3.6 4 0 0 4 4 3 0 BP28CT (NUC211) domain DUF3437 PF11919.8 EMR72137.1 - 0.06 13.3 0.5 32 4.5 0.0 4.6 6 0 0 6 6 4 0 Domain of unknown function (DUF3437) Tti2 PF10521.9 EMR72137.1 - 0.082 12.4 0.0 3.6 7.1 0.0 3.5 3 1 1 4 4 4 0 Tti2 family DUF3384 PF11864.8 EMR72137.1 - 0.1 11.5 0.3 0.3 9.9 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3384) ketoacyl-synt PF00109.26 EMR72138.1 - 7.9e-79 264.8 0.0 1.4e-78 264.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EMR72138.1 - 1.4e-61 208.4 0.1 2.3e-61 207.6 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EMR72138.1 - 3.1e-54 183.6 0.0 6.7e-54 182.5 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EMR72138.1 - 1.7e-52 178.9 0.5 4.1e-52 177.7 0.2 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMR72138.1 - 5.6e-35 119.9 0.0 1.3e-34 118.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EMR72138.1 - 1.9e-18 67.0 0.0 9.2e-18 64.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EMR72138.1 - 5e-16 59.1 0.0 1.2e-13 51.5 0.0 2.8 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EMR72138.1 - 1.1e-13 51.3 0.1 4e-13 49.5 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR72138.1 - 1.8e-10 42.0 0.0 4.5e-09 37.5 0.0 3.1 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EMR72138.1 - 3.1e-10 40.6 0.0 1.5e-09 38.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EMR72138.1 - 4.5e-10 39.3 0.0 1.4e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_11 PF08241.12 EMR72138.1 - 7.8e-10 39.3 0.0 2.4e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EMR72138.1 - 5.9e-09 36.2 0.1 1.5e-08 34.9 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EMR72138.1 - 6.5e-09 35.8 0.0 1.8e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR72138.1 - 2.1e-07 30.8 0.0 6.2e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EMR72138.1 - 0.00017 21.2 0.0 0.00044 19.9 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EMR72138.1 - 0.00023 20.6 0.2 0.00051 19.5 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 EMR72138.1 - 0.0019 18.1 0.3 0.0045 16.8 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 EMR72138.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 EMR72138.1 - 0.034 14.0 0.1 0.13 12.1 0.1 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Trp_DMAT PF11991.8 EMR72139.1 - 7e-96 321.8 0.0 8e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Peptidase_M15_4 PF13539.6 EMR72139.1 - 0.071 13.6 0.2 0.2 12.2 0.2 1.7 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF2273 PF10031.9 EMR72141.1 - 0.0041 17.1 1.4 0.0078 16.2 1.4 1.4 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) p450 PF00067.22 EMR72142.1 - 2.4e-38 132.1 0.0 3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chorismate_bind PF00425.18 EMR72143.1 - 3.9e-70 236.4 0.0 2.8e-65 220.4 0.0 2.8 2 1 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 EMR72143.1 - 8.8e-16 58.4 0.0 2.8e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region EcKinase PF02958.20 EMR72144.1 - 1e-12 48.0 0.1 3.7e-12 46.2 0.1 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EMR72144.1 - 7.3e-10 38.3 0.0 9.6e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 EMR72144.1 - 1.9e-06 28.0 0.4 2.9e-06 27.4 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HlyIII PF03006.20 EMR72145.1 - 4.4e-33 114.9 19.8 5.7e-33 114.5 19.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related p450 PF00067.22 EMR72146.1 - 1.4e-52 179.0 0.0 2.6e-39 135.3 0.0 2.6 1 1 1 2 2 2 2 Cytochrome P450 DUF3237 PF11578.8 EMR72147.1 - 2.2e-20 73.0 0.1 3.6e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) AMP-binding PF00501.28 EMR72148.1 - 4.9e-81 272.5 0.0 7.2e-81 271.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMR72148.1 - 5.5e-19 68.9 0.0 1.9e-18 67.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.15 EMR72149.1 - 1.1e-14 54.8 0.0 2.6e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Dysbindin PF04440.16 EMR72150.1 - 0.12 12.5 5.3 2.8 8.1 1.6 2.2 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) PAD PF03068.15 EMR72151.1 - 4e-127 424.4 0.0 4.9e-127 424.1 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) DUF5326 PF17260.2 EMR72152.1 - 0.027 14.6 0.2 0.042 14.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) adh_short PF00106.25 EMR72153.1 - 1.2e-29 103.2 3.2 2e-29 102.5 3.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72153.1 - 2.6e-23 82.8 1.7 4.3e-23 82.1 1.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72153.1 - 1.3e-10 41.4 1.0 1.8e-10 41.0 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR72153.1 - 0.019 14.5 1.9 0.047 13.1 1.9 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Amidohydro_2 PF04909.14 EMR72153.1 - 0.037 13.8 0.1 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase Rad4 PF03835.15 EMR72154.1 - 3.8e-16 59.1 1.1 7.9e-16 58.1 0.2 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EMR72154.1 - 2.2e-08 34.6 3.6 3.6e-08 33.8 3.6 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily p450 PF00067.22 EMR72155.1 - 3.1e-40 138.3 0.0 4e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EMR72157.1 - 1.1e-30 106.9 0.0 1.3e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lyase_1 PF00206.20 EMR72158.1 - 2.2e-30 106.2 0.0 8.5e-30 104.2 0.0 1.9 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 EMR72158.1 - 9.5e-13 48.5 0.0 1.1e-11 45.1 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus NRBF2 PF08961.10 EMR72159.1 - 0.00032 20.4 0.4 0.00046 19.8 0.4 1.3 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator ATG16 PF08614.11 EMR72159.1 - 0.05 13.8 7.6 0.071 13.3 7.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2992 PF11208.8 EMR72159.1 - 0.36 11.1 5.6 0.5 10.6 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF3450 PF11932.8 EMR72159.1 - 0.41 9.9 6.2 0.53 9.6 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CFEM PF05730.11 EMR72161.1 - 5.8e-07 29.5 8.7 1.2e-06 28.5 8.7 1.5 1 0 0 1 1 1 1 CFEM domain Fungal_trans PF04082.18 EMR72162.1 - 0.00017 20.7 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Destabilase PF05497.12 EMR72162.1 - 0.079 13.3 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Destabilase Sugar_tr PF00083.24 EMR72163.1 - 3.9e-94 316.1 21.5 4.7e-94 315.8 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR72163.1 - 3.8e-23 82.0 22.3 3.8e-23 82.0 22.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 EMR72163.1 - 9e-05 23.0 0.8 0.00042 20.8 0.8 2.2 1 0 0 1 1 1 1 Phage holin family 2 TRI12 PF06609.13 EMR72163.1 - 0.001 17.6 0.6 0.001 17.6 0.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-RNPHF PF08080.12 EMR72163.1 - 0.021 14.8 1.2 3.4 7.7 0.1 2.5 2 0 0 2 2 2 0 RNPHF zinc finger DUF2530 PF10745.9 EMR72163.1 - 2 8.7 12.7 0.19 12.0 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Torus PF16131.5 EMR72164.1 - 0.023 15.4 2.1 0.023 15.4 2.1 2.4 1 1 0 2 2 2 0 Torus domain Toxin_21 PF08091.11 EMR72164.1 - 6.2 6.8 11.8 7.6 6.6 2.9 2.4 2 0 0 2 2 2 0 Spider insecticidal peptide Glyco_hydro_43 PF04616.14 EMR72165.1 - 1.2e-26 93.7 0.5 1.6e-26 93.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Amidohydro_1 PF01979.20 EMR72166.1 - 4.8e-14 52.4 1.7 1.3e-12 47.7 1.7 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR72166.1 - 2.4e-12 47.1 9.6 1.6e-07 31.2 4.4 2.6 1 1 1 2 2 2 2 Amidohydrolase family Peptidase_S8 PF00082.22 EMR72167.1 - 1.5e-07 31.0 0.7 6.4e-07 28.9 0.7 2.0 1 1 0 1 1 1 1 Subtilase family Nodulin_late PF07127.11 EMR72168.1 - 3.1 8.2 5.4 7.3 7.0 1.1 2.3 2 0 0 2 2 2 0 Late nodulin protein Toxin_29 PF08116.11 EMR72168.1 - 6.7 6.8 15.3 4.7 7.3 6.0 2.9 2 0 0 2 2 2 0 PhTx neurotoxin family Glt_symporter PF03616.14 EMR72169.1 - 0.0042 15.8 0.8 0.0057 15.4 0.8 1.2 1 0 0 1 1 1 1 Sodium/glutamate symporter Poxvirus_B22R_C PF13168.6 EMR72169.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal PalH PF08733.10 EMR72169.1 - 2.7 6.9 8.0 5.1 6.0 8.0 1.3 1 1 0 1 1 1 0 PalH/RIM21 Amino_oxidase PF01593.24 EMR72170.1 - 1.2e-34 120.4 0.0 1.8e-34 119.8 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR72170.1 - 2.3e-07 30.9 0.0 5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR72170.1 - 0.00062 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR72170.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMR72170.1 - 0.0085 16.6 0.3 0.026 15.1 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR72170.1 - 0.019 14.2 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ATP-grasp_6 PF18419.1 EMR72170.1 - 0.16 11.6 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp-like domain Pyr_redox_3 PF13738.6 EMR72170.1 - 0.16 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FTA2 PF13095.6 EMR72171.1 - 0.002 17.8 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 7tm_1 PF00001.21 EMR72172.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) p450 PF00067.22 EMR72173.1 - 4.7e-54 183.9 0.2 2.1e-31 109.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 EMR72174.1 - 5.1e-21 75.0 24.9 6.2e-21 74.7 24.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily NOG1_N PF17835.1 EMR72175.1 - 2.3e-50 170.7 0.2 6.6e-50 169.2 0.2 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EMR72175.1 - 5.3e-27 93.6 3.0 1.1e-26 92.5 3.0 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EMR72175.1 - 4.4e-17 61.6 1.1 1.1e-16 60.3 1.1 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EMR72175.1 - 1.5e-15 57.2 0.0 3.4e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMR72175.1 - 1.2e-08 34.6 0.0 2.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMR72175.1 - 0.0072 16.2 0.4 1.4 8.8 0.0 2.8 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EMR72175.1 - 0.012 15.7 1.2 5.1 7.1 0.0 2.9 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 EMR72175.1 - 0.035 14.5 0.0 0.18 12.2 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EMR72175.1 - 0.16 12.1 0.0 0.86 9.8 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EMR72175.1 - 0.44 11.0 6.5 3.8 8.0 0.0 3.1 4 0 0 4 4 4 0 AAA domain adh_short PF00106.25 EMR72176.1 - 2.7e-21 75.9 0.1 8.6e-21 74.3 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72176.1 - 1.4e-12 47.7 0.1 2.8e-12 46.7 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72176.1 - 4.5e-07 30.0 0.2 5.9e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR72176.1 - 3.4e-06 26.7 0.1 7.6e-06 25.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR72176.1 - 0.00065 19.6 1.3 0.00092 19.1 1.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMR72176.1 - 0.0084 15.5 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMR72177.1 - 1.5e-13 51.0 0.6 5.9e-13 49.1 0.6 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMR72177.1 - 3.8e-12 46.2 1.4 2.2e-09 37.1 1.4 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMR72177.1 - 9.1e-10 38.5 1.2 2.3e-09 37.1 1.2 1.6 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 EMR72177.1 - 0.00065 19.7 0.4 0.0011 18.9 0.4 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMR72177.1 - 0.0014 18.1 0.7 0.026 13.9 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EMR72177.1 - 0.045 13.9 0.8 0.16 12.1 0.4 2.0 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EMR72177.1 - 0.083 13.3 0.1 0.87 10.0 0.1 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMR72177.1 - 0.11 12.7 0.3 0.34 11.2 0.3 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GARS_N PF02844.15 EMR72177.1 - 0.12 13.1 0.1 0.27 12.1 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Pribosyltran PF00156.27 EMR72178.1 - 2.8e-14 53.0 0.0 4.3e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Csm4_C PF17953.1 EMR72178.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 CRISPR Csm4 C-terminal domain Acetyltransf_10 PF13673.7 EMR72179.1 - 2.4e-12 46.9 0.0 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMR72179.1 - 6.2e-10 39.3 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR72179.1 - 1.3e-07 31.9 0.0 3.6e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMR72179.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N PF00107.26 EMR72180.1 - 6.7e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMR72180.1 - 4.3e-07 29.8 0.1 1.1e-06 28.4 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 EMR72182.1 - 1.3e-10 41.5 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMR72182.1 - 2.4e-09 37.1 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMR72182.1 - 9.7e-05 21.9 0.1 0.00019 21.0 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMR72182.1 - 0.0025 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EMR72182.1 - 0.011 15.2 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase COesterase PF00135.28 EMR72183.1 - 1.2e-13 50.8 0.0 5e-08 32.3 0.0 2.5 1 1 1 2 2 2 2 Carboxylesterase family LIP PF03583.14 EMR72184.1 - 1.6e-14 53.9 4.1 2e-13 50.3 4.1 2.1 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.7 EMR72184.1 - 7.4e-10 39.8 1.9 1.4e-09 38.9 1.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR72184.1 - 3.1e-07 29.9 0.1 9.6e-07 28.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMR72184.1 - 0.0013 18.3 1.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EMR72184.1 - 0.064 13.4 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 TAP-like protein CH PF00307.31 EMR72185.1 - 6.8e-67 222.5 0.0 3.7e-17 62.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EMR72185.1 - 2.7e-05 24.5 2.9 0.00013 22.3 0.2 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EMR72185.1 - 0.00091 18.6 0.9 0.54 9.9 0.2 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EMR72185.1 - 0.0029 17.4 0.4 0.18 11.8 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain MFS_1 PF07690.16 EMR72186.1 - 8e-47 159.9 29.1 6.1e-45 153.7 26.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR72186.1 - 5.6e-14 51.9 23.8 2.1e-13 49.9 23.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EMR72186.1 - 1e-05 24.2 4.8 1.7e-05 23.5 4.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EMR72186.1 - 0.00014 20.5 0.6 0.00014 20.5 0.6 4.3 4 1 0 4 4 4 2 MFS/sugar transport protein MFS_5 PF05631.14 EMR72186.1 - 0.00028 19.9 3.7 0.00092 18.2 1.7 2.3 2 1 0 2 2 2 1 Sugar-tranasporters, 12 TM OATP PF03137.20 EMR72186.1 - 0.00037 18.9 3.8 0.012 14.0 4.3 2.7 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EMR72186.1 - 0.00092 17.7 8.7 0.002 16.6 8.7 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector Transgly_assoc PF04226.13 EMR72186.1 - 0.4 11.0 11.6 1.1 9.6 5.2 3.4 2 0 0 2 2 2 0 Transglycosylase associated protein TMEM234 PF10639.9 EMR72187.1 - 3.6e-29 101.1 0.0 5.9e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Putative transmembrane family 234 Methyltransf_12 PF08242.12 EMR72188.1 - 9.7e-05 23.0 0.0 0.0002 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR72188.1 - 0.0004 21.0 0.0 0.0016 19.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR72188.1 - 0.00067 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR72188.1 - 0.00076 20.1 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF5632 PF18646.1 EMR72188.1 - 0.1 12.7 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5632) CDH-cyt PF16010.5 EMR72189.1 - 2.1e-68 229.6 1.6 1.8e-67 226.5 1.2 2.3 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_C PF05199.13 EMR72189.1 - 7.1e-25 88.2 0.5 1.4e-24 87.3 0.5 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR72189.1 - 7.8e-23 81.3 0.0 1.8e-22 80.1 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR72189.1 - 4.6e-06 26.0 0.3 0.00069 18.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DOMON PF03351.17 EMR72189.1 - 0.00063 20.0 0.1 0.0024 18.1 0.0 2.0 2 0 0 2 2 2 1 DOMON domain Pyr_redox_2 PF07992.14 EMR72189.1 - 0.0031 16.8 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR72189.1 - 0.005 16.5 0.6 0.005 16.5 0.6 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR72189.1 - 0.0052 17.0 0.1 0.014 15.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMR72189.1 - 0.0062 15.3 0.1 0.011 14.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EMR72189.1 - 0.073 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 EMR72189.1 - 0.14 12.4 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_61 PF03443.14 EMR72190.1 - 4.5e-45 154.1 0.2 5.6e-45 153.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF2771 PF10969.8 EMR72191.1 - 0.12 12.4 0.1 0.32 11.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2771) MBOAT PF03062.19 EMR72192.1 - 1.3e-39 136.6 19.0 1.3e-39 136.6 19.0 1.9 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EMR72192.1 - 5.3e-05 23.4 2.5 0.00016 21.8 2.5 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Plant_NMP1 PF06694.11 EMR72192.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) C2 PF00168.30 EMR72193.1 - 1.3e-17 63.9 0.0 2.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Hydrolase_6 PF13344.6 EMR72195.1 - 8.6e-25 86.8 0.0 1.8e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR72195.1 - 6e-16 58.3 1.4 1.1e-15 57.4 0.1 2.2 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EMR72195.1 - 0.00079 19.8 5.3 0.5 10.6 0.0 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMR72195.1 - 0.0062 16.6 0.1 1.7 8.7 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HMG_box PF00505.19 EMR72196.1 - 1.6e-07 31.7 0.5 3.1e-07 30.7 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR72196.1 - 0.048 14.3 1.0 0.082 13.5 0.2 1.8 2 0 0 2 2 2 0 HMG-box domain WSC PF01822.19 EMR72198.1 - 1.6e-33 114.7 25.0 4.9e-17 61.9 8.9 2.2 2 0 0 2 2 2 2 WSC domain SIM_C PF06621.12 EMR72198.1 - 6.2 6.8 6.5 1.7 8.6 1.6 2.0 1 1 1 2 2 2 0 Single-minded protein C-terminus Ferric_reduct PF01794.19 EMR72199.1 - 2.8e-22 79.1 6.6 6.1e-22 78.1 6.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMR72199.1 - 4.1e-20 72.5 0.0 6.7e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMR72199.1 - 1e-10 41.6 0.0 2.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EMR72199.1 - 6.6e-07 29.9 0.0 2.9e-05 24.7 0.0 2.5 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain adh_short PF00106.25 EMR72200.1 - 1.8e-22 79.8 0.1 2.7e-22 79.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72200.1 - 2.7e-14 53.3 0.1 3.4e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72200.1 - 1.3e-05 25.2 0.1 1.6e-05 24.9 0.1 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMR72200.1 - 0.0027 17.6 2.1 0.012 15.5 1.8 2.2 2 1 0 2 2 2 1 NAD(P)H-binding CPDase PF07823.11 EMR72201.1 - 8.8e-38 130.0 0.0 9.9e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EMR72201.1 - 0.00055 19.9 0.0 0.49 10.3 0.0 2.2 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily HMG_box PF00505.19 EMR72202.1 - 1.6e-14 54.0 1.1 2.7e-14 53.3 1.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMR72202.1 - 4.5e-08 33.6 0.9 7e-08 33.0 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain Ctr PF04145.15 EMR72203.1 - 1.4e-40 139.3 0.3 1.7e-40 139.1 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family SCIMP PF15050.6 EMR72203.1 - 0.014 15.8 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 SCIMP protein SK_channel PF03530.14 EMR72203.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.4 1 1 0 1 1 1 0 Calcium-activated SK potassium channel Herpes_LMP1 PF05297.11 EMR72203.1 - 4.1 6.5 4.7 0.59 9.3 1.0 1.4 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) GMC_oxred_N PF00732.19 EMR72204.1 - 2.5e-16 59.9 0.1 1.6e-15 57.2 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMR72204.1 - 1.6e-05 25.5 0.0 3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Peptidase_S9 PF00326.21 EMR72205.1 - 8.4e-05 22.1 0.1 0.00047 19.7 0.1 1.9 1 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EMR72205.1 - 0.00018 21.1 0.0 0.0044 16.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EMR72205.1 - 0.00031 20.1 0.0 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMR72205.1 - 0.0021 18.7 3.9 0.0036 17.9 3.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EMR72205.1 - 0.0029 17.5 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 EMR72205.1 - 0.021 14.5 0.0 0.21 11.2 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold DUF1100 PF06500.11 EMR72205.1 - 0.028 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 EMR72205.1 - 0.04 12.6 0.0 0.076 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UPF0227 PF05728.12 EMR72205.1 - 0.099 12.6 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Peptidase_S15 PF02129.18 EMR72205.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FMN_dh PF01070.18 EMR72206.1 - 4.4e-107 358.1 0.1 5.5e-107 357.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMR72206.1 - 0.00046 19.3 0.9 0.00079 18.5 0.9 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMR72206.1 - 0.007 15.5 0.2 0.01 15.0 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EMR72206.1 - 0.007 15.7 0.7 0.58 9.4 0.1 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EMR72206.1 - 0.014 14.9 1.1 0.14 11.6 0.1 2.5 2 1 1 3 3 3 0 Histidine biosynthesis protein Ytp1 PF10355.9 EMR72207.1 - 5.7e-70 235.7 14.8 1.7e-69 234.1 14.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Ni_hydr_CYTB PF01292.20 EMR72207.1 - 0.003 17.2 5.0 0.003 17.2 5.0 3.0 1 1 1 2 2 2 1 Prokaryotic cytochrome b561 p450 PF00067.22 EMR72208.1 - 5.8e-23 81.4 0.0 9.9e-23 80.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EMR72209.1 - 4e-27 95.4 0.0 6.6e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD-oxidase_C PF02913.19 EMR72211.1 - 9.5e-63 212.1 0.4 1.5e-62 211.5 0.4 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMR72211.1 - 5.4e-35 120.1 0.0 1.1e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_18 PF00704.28 EMR72211.1 - 8.2e-18 65.2 0.0 1.4e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1754 PF08555.10 EMR72213.1 - 3.9e-07 30.8 26.8 2.8e-05 24.8 26.8 2.4 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CENP-B_dimeris PF09026.10 EMR72213.1 - 0.64 10.4 9.5 1 9.8 9.1 1.5 1 1 0 1 1 1 0 Centromere protein B dimerisation domain NPR3 PF03666.13 EMR72213.1 - 1.2 7.8 8.1 1.6 7.4 8.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TMEM154 PF15102.6 EMR72213.1 - 3.1 7.7 5.3 0.57 10.1 0.2 1.9 1 1 1 2 2 2 0 TMEM154 protein family POX PF07526.11 EMR72213.1 - 3.4 8.2 6.2 9.3 6.8 6.2 1.7 1 1 0 1 1 1 0 Associated with HOX Trypan_PARP PF05887.11 EMR72213.1 - 5.8 6.9 9.3 0.84 9.6 3.5 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FA_desaturase PF00487.24 EMR72215.1 - 1.7 8.4 8.0 3 7.6 8.0 1.4 1 0 0 1 1 1 0 Fatty acid desaturase SK_channel PF03530.14 EMR72215.1 - 3.9 7.5 7.7 0.33 11.0 2.2 2.0 2 0 0 2 2 2 0 Calcium-activated SK potassium channel adh_short_C2 PF13561.6 EMR72216.1 - 7.2e-46 156.6 0.0 4.1e-28 98.5 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR72216.1 - 8e-35 120.1 0.0 8.8e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMR72216.1 - 0.0013 18.7 0.0 0.0027 17.6 0.0 1.5 2 0 0 2 2 2 1 KR domain TFIIB PF00382.19 EMR72216.1 - 0.079 13.0 0.3 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DUF1776 PF08643.10 EMR72216.1 - 0.13 11.6 0.1 0.22 10.8 0.1 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Asp PF00026.23 EMR72218.1 - 6.7e-64 216.3 0.3 9.8e-64 215.7 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR72218.1 - 1.3e-10 41.8 1.1 4.9e-07 30.2 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal F-box-like PF12937.7 EMR72220.1 - 9e-09 35.1 0.2 3.8e-08 33.1 0.2 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EMR72220.1 - 0.0088 15.9 2.6 0.46 10.4 0.2 2.7 2 0 0 2 2 2 2 F-box domain EamA PF00892.20 EMR72221.1 - 5.1e-09 36.4 30.7 6.3e-05 23.2 4.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 EMR72221.1 - 7.7e-05 21.8 13.4 7.7e-05 21.8 13.4 2.8 2 1 0 2 2 2 1 Ceramide synthase regulator CDC45 PF02724.14 EMR72221.1 - 0.01 14.2 1.1 0.014 13.7 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nuc_sug_transp PF04142.15 EMR72221.1 - 0.078 12.1 8.9 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter Aldo_ket_red PF00248.21 EMR72222.1 - 5.1e-51 173.6 0.0 5.8e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family APC_u13 PF16634.5 EMR72222.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr and SAMP 5_nucleotid_C PF02872.18 EMR72223.1 - 1.8e-38 132.2 0.0 5.3e-38 130.7 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EMR72223.1 - 4.1e-07 30.7 0.1 6.8e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Abhydrolase_3 PF07859.13 EMR72224.1 - 3.9e-21 75.9 0.0 7e-20 71.8 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR72224.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Eno-Rase_NADH_b PF12242.8 EMR72224.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA PF00004.29 EMR72225.1 - 1.5e-10 41.6 0.0 3.5e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR72225.1 - 1.6e-05 25.3 0.0 2.5e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR72225.1 - 2.4e-05 24.6 0.0 0.00011 22.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMR72225.1 - 0.0014 18.5 0.4 0.0045 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Phage_int_SAM_5 PF13102.6 EMR72225.1 - 0.0022 18.3 0.1 1.3 9.4 0.1 2.3 1 1 1 2 2 2 2 Phage integrase SAM-like domain AAA_5 PF07728.14 EMR72225.1 - 0.0034 17.4 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EMR72225.1 - 0.0041 16.9 0.4 0.0092 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 EMR72225.1 - 0.0075 16.4 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Torsin Mg_chelatase PF01078.21 EMR72225.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EMR72225.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EMR72225.1 - 0.03 14.0 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EMR72225.1 - 0.041 14.2 1.5 0.06 13.7 0.1 1.9 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EMR72225.1 - 0.045 13.9 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EMR72225.1 - 0.068 12.9 0.1 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain cpYpsA PF12694.7 EMR72225.1 - 0.079 12.8 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Circularly permutated YpsA SLOG family Rad17 PF03215.15 EMR72225.1 - 0.088 12.7 0.3 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_6 PF12774.7 EMR72225.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region T2SSE PF00437.20 EMR72225.1 - 0.15 11.1 0.2 0.48 9.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein FAM184 PF15665.5 EMR72226.1 - 0.034 13.9 10.1 0.056 13.2 10.1 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Cep57_MT_bd PF06657.13 EMR72226.1 - 0.054 14.0 4.7 0.37 11.3 4.5 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Nbl1_Borealin_N PF10444.9 EMR72226.1 - 0.16 11.6 1.8 0.38 10.4 1.8 1.7 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal OmpH PF03938.14 EMR72226.1 - 1.1 9.6 12.3 2.6 8.4 12.3 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 EMR72226.1 - 1.6 6.5 5.9 2.2 6.1 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EMR72226.1 - 4.4 6.6 9.4 7.2 5.9 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_2 PF12796.7 EMR72228.1 - 3.4e-15 56.4 0.6 5.9e-07 30.0 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EMR72228.1 - 3.8e-13 49.2 0.3 0.00014 22.1 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EMR72228.1 - 1.8e-11 44.3 0.3 0.0029 18.1 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR72228.1 - 7.3e-10 38.2 0.1 0.0056 17.1 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EMR72228.1 - 6.1e-09 36.0 0.3 1e-05 25.7 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.13 EMR72228.1 - 7.3e-06 25.8 0.2 4.8e-05 23.2 0.2 2.4 1 1 0 1 1 1 1 KilA-N domain Cep57_MT_bd PF06657.13 EMR72228.1 - 2.2 8.8 4.7 49 4.5 0.0 3.6 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Ribosomal_S24e PF01282.19 EMR72230.1 - 3.8e-33 113.3 0.0 6.8e-33 112.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e Amino_oxidase PF01593.24 EMR72231.1 - 1.3e-52 179.6 0.0 1.7e-52 179.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 EMR72231.1 - 3.5e-16 59.3 0.1 6.1e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 EMR72231.1 - 1.9e-10 40.8 0.3 1.9e-10 40.8 0.3 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMR72231.1 - 2.9e-07 29.9 0.3 5.8e-07 28.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EMR72231.1 - 2.1e-06 27.4 3.0 2.1e-06 27.4 3.0 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EMR72231.1 - 5.7e-06 26.1 0.6 1.7e-05 24.6 0.6 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMR72231.1 - 4.6e-05 22.6 0.7 0.0095 15.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 EMR72231.1 - 5.2e-05 22.1 1.9 0.0035 16.1 0.6 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EMR72231.1 - 0.00016 21.0 0.1 0.038 13.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR72231.1 - 0.00065 19.0 0.3 0.048 12.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR72231.1 - 0.0039 16.5 0.5 0.0082 15.4 0.5 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EMR72231.1 - 0.035 13.2 2.5 0.038 13.1 0.9 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EMR72231.1 - 0.068 13.7 0.2 0.25 11.9 0.2 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMR72231.1 - 0.29 10.3 2.8 0.71 9.1 1.4 2.1 2 0 0 2 2 2 0 FAD binding domain Pkinase PF00069.25 EMR72233.1 - 3e-69 233.3 0.0 3.5e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR72233.1 - 9.5e-32 110.3 0.0 1.3e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMR72233.1 - 0.0089 15.0 0.0 0.02 13.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMR72233.1 - 0.046 13.1 0.1 0.094 12.1 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR72233.1 - 0.058 13.3 0.1 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EMR72233.1 - 0.075 12.6 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Dioxygenase_C PF00775.21 EMR72234.1 - 1.2e-08 34.6 0.1 1.9e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase ABC_tran PF00005.27 EMR72236.1 - 1.9e-52 177.4 0.1 1.1e-29 103.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR72236.1 - 1.4e-51 175.8 31.2 7.8e-36 124.1 13.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EMR72236.1 - 2.8e-06 26.9 4.7 0.043 13.2 0.9 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMR72236.1 - 2.6e-05 24.2 0.9 0.33 10.7 0.3 3.6 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EMR72236.1 - 2.8e-05 24.2 1.1 0.14 12.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR72236.1 - 0.00015 21.7 0.5 0.054 13.4 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EMR72236.1 - 0.00028 21.3 0.1 0.091 13.1 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMR72236.1 - 0.00087 19.0 1.6 0.48 10.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EMR72236.1 - 0.0014 18.0 0.1 0.15 11.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 EMR72236.1 - 0.004 17.4 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EMR72236.1 - 0.0083 16.4 1.4 2.5 8.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMR72236.1 - 0.032 13.8 0.5 1.6 8.3 0.1 2.9 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 EMR72236.1 - 0.04 13.6 0.6 1.3 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EMR72236.1 - 0.042 13.5 0.0 4 7.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EMR72236.1 - 0.042 14.4 0.0 13 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EMR72236.1 - 0.046 13.4 0.3 14 5.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EMR72236.1 - 0.049 13.1 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EMR72236.1 - 0.12 11.4 0.6 3.1 6.8 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_24 PF13479.6 EMR72236.1 - 0.14 11.9 0.1 8.8 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EMR72236.1 - 0.17 11.6 0.3 3.9 7.2 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EMR72236.1 - 0.17 11.9 3.6 1.1 9.2 0.3 2.6 2 0 0 2 2 2 0 Dynamin family PhoH PF02562.16 EMR72236.1 - 0.26 10.7 1.0 17 4.8 0.1 3.2 3 0 0 3 3 3 0 PhoH-like protein DUF2273 PF10031.9 EMR72236.1 - 0.3 11.1 0.1 0.3 11.1 0.1 3.9 4 0 0 4 4 3 0 Small integral membrane protein (DUF2273) AAA_28 PF13521.6 EMR72236.1 - 0.34 11.2 2.3 0.98 9.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EMR72236.1 - 0.42 10.3 2.9 13 5.4 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 EMR72236.1 - 0.45 11.0 8.6 3.3 8.2 0.2 2.9 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 EMR72236.1 - 0.52 10.4 6.2 1.5 8.9 0.5 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Pex24p PF06398.11 EMR72236.1 - 0.77 8.7 6.4 0.47 9.4 0.7 2.4 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Meth_synt_2 PF01717.18 EMR72237.1 - 7.2e-11 41.9 0.0 4.6e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain FtsJ PF01728.19 EMR72238.1 - 2.9e-17 63.4 0.0 4.3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EMR72238.1 - 0.21 11.2 0.2 0.93 9.1 0.1 1.9 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 EMR72239.1 - 7.5e-15 55.2 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR72239.1 - 1.1e-10 41.5 0.0 3.1e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR72239.1 - 1.2e-10 42.0 0.0 3.4e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR72239.1 - 4.4e-08 33.8 0.0 3.3e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR72239.1 - 6.7e-07 29.9 0.0 3.2e-06 27.7 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMR72239.1 - 0.00045 19.7 0.0 0.0014 18.1 0.0 1.8 1 1 1 2 2 2 1 Putative methyltransferase MTS PF05175.14 EMR72239.1 - 0.0013 18.3 0.0 0.0065 16.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 EMR72239.1 - 0.0015 18.7 0.0 0.002 18.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.18 EMR72239.1 - 0.0032 17.0 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 EMR72239.1 - 0.004 16.5 0.0 0.012 14.9 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 EMR72239.1 - 0.0055 16.1 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EMR72239.1 - 0.008 15.5 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMR72239.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EMR72239.1 - 0.18 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 EMR72239.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Sulfatase PF00884.23 EMR72240.1 - 3.5e-40 138.3 0.2 2e-23 83.3 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Phosphodiest PF01663.22 EMR72240.1 - 0.027 14.1 0.0 0.063 12.8 0.0 1.6 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4495 PF14906.6 EMR72240.1 - 0.053 12.6 0.1 0.08 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) Ndr PF03096.14 EMR72240.1 - 0.084 11.6 0.0 0.68 8.6 0.0 2.0 2 0 0 2 2 2 0 Ndr family DUF2330 PF10092.9 EMR72240.1 - 0.16 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Methyltransf_11 PF08241.12 EMR72241.1 - 3.1e-14 53.4 0.0 5.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR72241.1 - 4.4e-13 49.8 0.0 8.2e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR72241.1 - 1.6e-09 37.5 0.0 6e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMR72241.1 - 3.9e-09 37.1 0.0 7.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR72241.1 - 4.4e-07 29.8 0.0 6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMR72241.1 - 7.1e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMR72241.1 - 0.00025 20.6 0.0 0.00054 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain MFS_1 PF07690.16 EMR72243.1 - 7.9e-31 107.3 28.7 7.9e-31 107.3 28.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR72243.1 - 0.0024 16.8 2.8 0.0024 16.8 2.8 1.9 2 0 0 2 2 2 1 MFS_1 like family Amino_oxidase PF01593.24 EMR72244.1 - 8.1e-11 41.9 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMR72244.1 - 1.2e-09 38.3 0.0 2.9e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMR72244.1 - 1.4e-05 24.5 0.1 0.003 16.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMR72244.1 - 0.00082 18.7 0.2 0.0019 17.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 EMR72244.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR72244.1 - 0.0047 16.3 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMR72244.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EMR72244.1 - 0.023 13.4 0.0 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 EMR72244.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EMR72244.1 - 0.03 14.6 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 EMR72244.1 - 0.044 13.8 0.5 0.16 11.9 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EMR72244.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3455 PF11937.8 EMR72245.1 - 2e-28 99.8 0.0 3.5e-28 99.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) FPN1 PF06963.12 EMR72246.1 - 2.3e-92 309.9 12.3 3.5e-57 193.9 2.5 2.0 1 1 1 2 2 2 2 Ferroportin1 (FPN1) 2OG-FeII_Oxy_2 PF13532.6 EMR72246.1 - 3.7e-12 46.8 0.0 5.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxidored_q6 PF01058.22 EMR72247.1 - 1.9e-22 79.5 0.1 2.7e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Methyltransf_16 PF10294.9 EMR72248.1 - 8.3e-19 68.0 0.0 1.2e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 EMR72248.1 - 0.00019 21.3 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EMR72248.1 - 0.00033 20.5 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR72248.1 - 0.0026 18.4 0.1 0.0049 17.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMR72248.1 - 0.0037 16.7 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EMR72248.1 - 0.0073 15.9 0.1 0.022 14.3 0.1 1.6 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EMR72248.1 - 0.038 13.8 0.1 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 EMR72248.1 - 0.082 12.7 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) MFS_1 PF07690.16 EMR72249.1 - 1.4e-38 132.7 53.0 3.1e-38 131.6 48.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Arylsulfotran_2 PF14269.6 EMR72250.1 - 1.8e-69 234.4 2.6 2.6e-69 233.9 1.6 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMR72250.1 - 1.6e-11 43.8 0.3 4.8e-10 38.9 0.3 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) CVNH PF08881.10 EMR72251.1 - 1.5e-07 32.0 0.6 2.2e-07 31.5 0.6 1.2 1 0 0 1 1 1 1 CVNH domain FMN_dh PF01070.18 EMR72252.1 - 3.1e-28 98.8 0.0 3.4e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Peptidase_M3 PF01432.20 EMR72253.1 - 1.8e-81 274.7 0.1 4.2e-65 220.8 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M3 Cupin_6 PF12852.7 EMR72253.1 - 0.006 16.3 0.3 0.012 15.4 0.1 1.5 2 0 0 2 2 2 1 Cupin Peptidase_M91 PF14891.6 EMR72253.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Effector protein MFS_1 PF07690.16 EMR72256.1 - 1.1e-12 47.6 16.6 1.5e-10 40.6 3.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR72256.1 - 0.00046 19.2 0.3 0.00086 18.3 0.3 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter LIAS_N PF16881.5 EMR72256.1 - 0.2 12.1 0.0 0.47 10.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Pex14_N PF04695.13 EMR72258.1 - 7.8 7.1 11.2 92 3.7 11.2 2.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sulfotransfer_4 PF17784.1 EMR72259.1 - 1e-60 205.2 0.0 1.3e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMR72259.1 - 6.8e-06 26.6 0.0 0.026 14.9 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Glyco_transf_25 PF01755.17 EMR72260.1 - 9e-06 25.7 0.0 0.0074 16.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Foie-gras_1 PF11817.8 EMR72260.1 - 0.057 13.0 0.2 0.079 12.5 0.2 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 ApbA PF02558.16 EMR72261.1 - 1.3e-08 34.7 0.0 1.3e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 EMR72261.1 - 0.0019 18.8 0.0 0.0023 18.5 0.0 1.1 1 0 0 1 1 1 1 PglD N-terminal domain ThiF PF00899.21 EMR72261.1 - 0.0049 16.2 0.3 0.0066 15.8 0.3 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EMR72261.1 - 0.036 14.1 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EMR72261.1 - 0.083 13.7 0.1 0.086 13.7 0.1 1.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.25 EMR72263.1 - 2.7e-40 137.9 0.0 3.5e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72263.1 - 3.1e-22 79.3 0.0 4.1e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72263.1 - 3.5e-09 36.8 0.2 9.7e-09 35.4 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMR72263.1 - 0.0082 15.6 0.1 0.019 14.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMR72263.1 - 0.018 14.5 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 EMR72263.1 - 0.11 12.8 0.2 0.23 11.7 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 EMR72263.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 EMR72263.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 EMR72263.1 - 0.15 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding ApbA_C PF08546.11 EMR72264.1 - 1.3e-25 90.0 0.0 1.9e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EMR72264.1 - 2.2e-05 24.1 0.1 3.3e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA LMWPc PF01451.21 EMR72265.1 - 3.7e-37 127.9 0.0 4.3e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PCRF PF03462.18 EMR72266.1 - 5.1e-46 157.0 0.0 8.7e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EMR72266.1 - 3.9e-33 113.8 1.0 7e-33 113.0 1.0 1.4 1 0 0 1 1 1 1 RF-1 domain TAtT PF16811.5 EMR72267.1 - 0.029 13.7 0.1 7.2 5.8 0.0 2.1 2 0 0 2 2 2 0 TRAP transporter T-component DUF3180 PF11377.8 EMR72268.1 - 0.0085 16.2 1.0 0.13 12.4 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3180) DUF4446 PF14584.6 EMR72268.1 - 0.033 14.2 0.7 0.079 12.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4834 PF16118.5 EMR72268.1 - 0.041 14.8 0.3 0.041 14.8 0.3 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) AAA_assoc PF14363.6 EMR72268.1 - 0.071 13.5 0.4 0.18 12.2 0.4 1.8 1 1 0 1 1 1 0 Domain associated at C-terminal with AAA Tetraspanin PF00335.20 EMR72268.1 - 0.6 9.8 9.4 0.071 12.8 4.9 1.7 2 1 0 2 2 2 0 Tetraspanin family DUF1980 PF09323.10 EMR72268.1 - 1.2 9.0 6.7 1.5 8.7 5.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Phage_holin_3_6 PF07332.11 EMR72268.1 - 2.9 8.0 6.6 1.3 9.1 1.1 2.7 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF898 PF05987.13 EMR72268.1 - 4.8 6.1 11.4 62 2.5 11.4 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) OAD_gamma PF04277.13 EMR72268.1 - 6.1 7.5 7.4 1.8 9.2 0.6 3.1 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DHHC PF01529.20 EMR72268.1 - 6.1 6.9 16.3 1.6 8.8 5.7 2.3 1 1 2 3 3 3 0 DHHC palmitoyltransferase TPR_12 PF13424.6 EMR72269.1 - 6.3e-06 26.4 0.1 0.00019 21.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Clr5 PF14420.6 EMR72269.1 - 8.8e-05 22.6 2.7 8.8e-05 22.6 2.7 2.4 2 0 0 2 2 2 1 Clr5 domain ALO PF04030.14 EMR72269.1 - 0.0026 17.6 0.1 0.0046 16.8 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Pan3_PK PF18101.1 EMR72270.1 - 4.3e-59 198.4 0.0 5.9e-59 198.0 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Succ_CoA_lig PF13607.6 EMR72270.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain LSM PF01423.22 EMR72272.1 - 7.9e-20 70.3 0.1 9.9e-20 70.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 EMR72272.1 - 0.13 12.8 10.6 0.22 12.1 10.6 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 dCMP_cyt_deam_1 PF00383.23 EMR72273.1 - 3.4e-19 68.6 0.0 8.4e-19 67.3 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMR72273.1 - 3.2e-14 52.9 0.0 1.1e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 EMR72273.1 - 0.00013 22.0 0.7 0.012 15.7 0.1 2.6 1 1 1 2 2 2 2 Bd3614-like deaminase PX PF00787.24 EMR72275.1 - 1.3e-24 86.4 0.0 1.5e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 PX domain His_Phos_1 PF00300.22 EMR72276.1 - 2e-34 119.0 1.0 1.7e-17 63.8 0.6 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AA_permease PF00324.21 EMR72278.1 - 1.6e-95 320.5 38.3 2e-95 320.2 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR72278.1 - 1.2e-24 87.0 40.5 2e-24 86.2 40.5 1.4 1 1 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 EMR72279.1 - 0.084 13.0 8.7 0.16 12.1 8.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PhosphMutase PF10143.9 EMR72279.1 - 0.17 11.7 0.2 0.29 11.0 0.2 1.3 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Epimerase PF01370.21 EMR72280.1 - 7.3e-19 68.2 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMR72280.1 - 1.4e-10 40.8 0.1 2.9e-09 36.5 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EMR72280.1 - 5.5e-09 35.4 0.1 8.5e-09 34.8 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMR72280.1 - 9.3e-08 31.8 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMR72280.1 - 1.8e-05 24.3 0.3 6.6e-05 22.5 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EMR72280.1 - 2.6e-05 23.5 0.2 6.5e-05 22.2 0.1 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMR72280.1 - 3.8e-05 23.6 0.8 9.5e-05 22.4 0.2 2.0 2 1 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 EMR72280.1 - 0.00047 20.2 0.0 0.00089 19.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 EMR72280.1 - 0.0039 17.1 0.0 0.0072 16.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EMR72280.1 - 0.016 15.5 0.1 0.028 14.7 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Kelch_1 PF01344.25 EMR72280.1 - 0.085 12.5 0.2 0.43 10.2 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Mito_carr PF00153.27 EMR72281.1 - 1.8e-68 226.5 0.1 1.4e-22 79.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Response_reg PF00072.24 EMR72283.1 - 1.1e-23 83.5 0.0 7.2e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain Secretin_N PF03958.17 EMR72283.1 - 0.018 15.5 0.1 0.036 14.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Roughex PF06020.11 EMR72283.1 - 0.02 14.0 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Methyltransf_23 PF13489.6 EMR72285.1 - 1.6e-16 60.6 0.0 2.1e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMR72285.1 - 5.4e-15 55.8 0.0 1.2e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR72285.1 - 4.1e-14 53.1 0.0 9.4e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR72285.1 - 3.5e-13 49.6 0.0 7.6e-13 48.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR72285.1 - 8.2e-12 45.7 0.3 1.8e-11 44.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMR72285.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EMR72285.1 - 0.00028 20.9 0.1 0.00099 19.1 0.1 1.9 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EMR72285.1 - 0.00036 19.9 0.0 0.00065 19.1 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase HAND PF09110.11 EMR72285.1 - 0.01 16.6 0.2 7.1 7.4 2.4 2.3 2 0 0 2 2 2 0 HAND Flavi_DEAD PF07652.14 EMR72285.1 - 0.036 14.0 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Flavivirus DEAD domain TPMT PF05724.11 EMR72285.1 - 0.044 13.4 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Utp14 PF04615.13 EMR72285.1 - 0.049 12.2 3.6 0.068 11.8 3.6 1.1 1 0 0 1 1 1 0 Utp14 protein DNA_pol_phi PF04931.13 EMR72285.1 - 0.089 10.9 6.8 0.1 10.7 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EMR72285.1 - 0.11 10.7 2.8 0.13 10.5 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein MTS PF05175.14 EMR72285.1 - 0.18 11.3 0.1 0.35 10.4 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EMR72285.1 - 0.26 10.3 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RRN3 PF05327.11 EMR72285.1 - 0.77 8.2 3.3 0.92 8.0 3.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EMR72285.1 - 1.8 6.7 7.6 2.4 6.3 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EMR72285.1 - 2.2 7.6 9.2 3.3 6.9 9.2 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 EMR72285.1 - 2.6 8.5 9.8 1.6 9.2 6.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal E1-E2_ATPase PF00122.20 EMR72286.1 - 6.2e-35 120.4 18.9 6.2e-29 100.8 0.4 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMR72286.1 - 1.5e-24 86.7 7.7 1.5e-24 86.7 7.7 3.0 2 2 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMR72286.1 - 5e-20 72.7 0.0 8.2e-19 68.7 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMR72286.1 - 2.4e-18 66.0 0.0 5.2e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMR72286.1 - 2.4e-17 62.4 0.0 5.3e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMR72286.1 - 0.0002 21.2 0.1 0.00075 19.3 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DctM PF06808.12 EMR72286.1 - 0.017 14.0 8.1 0.02 13.8 0.2 2.7 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporter, DctM component DUF3439 PF11921.8 EMR72287.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-like PF04071.12 EMR72287.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich small domain DUF4360 PF14273.6 EMR72288.1 - 1.6e-06 28.2 0.0 3.5e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) PRP21_like_P PF12230.8 EMR72289.1 - 3.1e-56 190.7 11.3 3.1e-56 190.7 11.3 2.8 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EMR72289.1 - 2.1e-31 107.7 2.8 1.5e-18 66.5 0.5 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 EMR72289.1 - 0.0033 17.0 0.3 0.0086 15.7 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Phostensin_N PF13916.6 EMR72289.1 - 8.3 6.8 14.0 7.9 6.9 6.3 2.8 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal p450 PF00067.22 EMR72290.1 - 3.1e-74 250.4 0.0 4.6e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EMR72290.1 - 2.7e-29 102.4 0.1 4.5e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PMT PF02366.18 EMR72292.1 - 2.6e-79 266.3 15.7 2.6e-79 266.3 15.7 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMR72292.1 - 4.1e-68 228.9 12.1 4.1e-68 228.9 12.1 2.2 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMR72292.1 - 4.8e-48 163.5 0.0 8.6e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 MIR domain CDC37_C PF08564.10 EMR72293.1 - 0.065 13.4 0.2 0.092 12.9 0.2 1.2 1 0 0 1 1 1 0 Cdc37 C terminal domain IBR PF01485.21 EMR72293.1 - 0.37 11.0 10.1 1.3 9.3 10.2 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Meleagrin PF08189.11 EMR72294.1 - 0.043 13.5 1.0 0.11 12.2 1.0 1.7 1 0 0 1 1 1 0 Meleagrin/Cygnin family UBA_4 PF14555.6 EMR72295.1 - 5e-11 42.2 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EMR72295.1 - 0.00027 21.1 0.0 0.00069 19.8 0.0 1.7 1 0 0 1 1 1 1 UBX domain DUF1682 PF07946.14 EMR72295.1 - 0.13 11.5 5.0 0.21 10.8 4.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) DDRGK PF09756.9 EMR72295.1 - 3.4 7.2 7.3 6.8 6.2 7.3 1.4 1 0 0 1 1 1 0 DDRGK domain MARVEL PF01284.23 EMR72296.1 - 0.00057 19.9 14.5 0.0023 18.0 8.5 2.1 1 1 1 2 2 2 1 Membrane-associating domain VIT1 PF01988.19 EMR72296.1 - 0.0032 17.4 2.7 0.0042 17.0 2.7 1.3 1 0 0 1 1 1 1 VIT family DUF3810 PF12725.7 EMR72296.1 - 8.3 5.6 7.1 74 2.5 6.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Herpes_LMP1 PF05297.11 EMR72296.1 - 9.2 5.3 7.8 18 4.4 7.8 1.4 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3482 PF11981.8 EMR72297.1 - 0.031 13.7 0.3 0.034 13.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) FTR1 PF03239.14 EMR72297.1 - 0.031 13.4 0.1 0.031 13.4 0.1 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family SET PF00856.28 EMR72298.1 - 2.2e-15 57.5 0.7 2.2e-15 57.5 0.7 2.9 3 1 0 3 3 3 1 SET domain HicB PF05534.12 EMR72299.1 - 0.075 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 HicB family Bot1p PF12298.8 EMR72300.1 - 4.4e-20 72.6 4.6 9e-20 71.5 4.5 1.6 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Sortilin-Vps10 PF15902.5 EMR72300.1 - 0.05 12.4 0.1 0.063 12.1 0.1 1.2 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, FAD_binding_3 PF01494.19 EMR72301.1 - 6.1e-20 71.8 3.3 4.7e-13 49.1 0.2 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EMR72301.1 - 4.3e-06 26.2 0.4 4.4e-05 22.9 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR72301.1 - 2.3e-05 24.1 7.5 0.00026 20.7 3.9 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 EMR72301.1 - 3.2e-05 23.1 0.0 0.22 10.6 0.0 2.3 2 1 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 EMR72301.1 - 3.3e-05 24.0 1.1 0.00012 22.3 0.9 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMR72301.1 - 0.00036 21.0 0.3 0.00085 19.8 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMR72301.1 - 0.011 14.7 3.1 0.12 11.3 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 EMR72301.1 - 0.021 14.1 4.5 0.12 11.6 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EMR72301.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ectoine_synth PF06339.12 EMR72302.1 - 0.064 13.5 0.6 1.4 9.1 0.2 2.3 1 1 0 2 2 2 0 Ectoine synthase BAR PF03114.18 EMR72303.1 - 3.5e-15 56.3 0.1 4.7e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EMR72303.1 - 6.7e-12 44.8 0.0 1.2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMR72303.1 - 6.7e-11 41.9 0.0 1.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMR72303.1 - 2.7e-06 26.9 0.0 5.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Caskin-Pro-rich PF16907.5 EMR72303.1 - 0.01 16.3 1.3 0.01 16.3 1.3 3.6 4 1 0 4 4 4 0 Proline rich region of Caskin proteins Urb2 PF10441.9 EMR72304.1 - 2e-58 197.7 0.3 3.8e-58 196.8 0.0 1.6 2 0 0 2 2 2 1 Urb2/Npa2 family SR-25 PF10500.9 EMR72304.1 - 1.3 8.6 10.8 2.1 7.9 10.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 EMR72304.1 - 8.8 6.7 14.8 2.7 8.3 11.2 2.0 1 1 1 2 2 2 0 Early growth response N-terminal domain DUF4419 PF14388.6 EMR72305.1 - 2.2e-06 27.4 0.0 2.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) GHMP_kinases_N PF00288.26 EMR72305.1 - 0.065 13.5 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 GHMP kinases N terminal domain DUF543 PF04418.12 EMR72306.1 - 3.9e-30 103.7 0.0 4.5e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ABC_cobalt PF09819.9 EMR72306.1 - 0.03 14.5 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component p450 PF00067.22 EMR72307.1 - 9.8e-59 199.3 0.0 1.2e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_7 PF03441.14 EMR72308.1 - 1.3e-71 240.3 0.0 1.9e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EMR72308.1 - 3.5e-18 66.1 0.0 6.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase MFS_1 PF07690.16 EMR72309.1 - 3.1e-23 82.3 11.6 1.6e-11 43.7 2.1 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF1772 PF08592.11 EMR72309.1 - 0.0091 16.3 3.8 2.2 8.6 5.4 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1772) LapA_dom PF06305.11 EMR72309.1 - 0.14 12.0 0.0 2.4 8.0 0.0 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain LPG_synthase_TM PF03706.13 EMR72309.1 - 0.36 10.3 11.4 0.24 10.9 4.2 3.3 2 1 1 4 4 4 0 Lysylphosphatidylglycerol synthase TM region Abhydrolase_3 PF07859.13 EMR72310.1 - 3.8e-33 115.1 0.0 1.2e-22 80.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMR72310.1 - 0.083 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase SDA1 PF05285.12 EMR72312.1 - 3.6e-90 302.9 65.0 5.7e-89 299.0 54.8 2.9 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EMR72312.1 - 6.8e-19 67.9 0.1 1.8e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Dict-STAT-coil PF09267.10 EMR72312.1 - 0.013 15.9 1.7 0.025 14.9 0.3 2.2 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil GMC_oxred_C PF05199.13 EMR72314.1 - 3.3e-33 115.2 0.0 7.5e-33 114.1 0.0 1.6 2 0 0 2 2 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMR72314.1 - 1.5e-31 109.9 0.0 4.6e-29 101.7 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 EMR72314.1 - 9.8e-06 24.9 0.0 0.00011 21.4 0.0 2.4 2 1 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 EMR72314.1 - 5e-05 22.7 0.0 0.00061 19.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR72314.1 - 0.00013 22.1 0.1 0.00047 20.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR72314.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EMR72314.1 - 0.0023 17.3 0.1 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMR72314.1 - 0.0049 16.3 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMR72314.1 - 0.0059 15.9 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMR72314.1 - 0.015 14.0 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein TcpF PF06340.11 EMR72314.1 - 0.017 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F DAO PF01266.24 EMR72314.1 - 0.024 14.2 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EMR72314.1 - 0.12 11.4 0.1 0.45 9.5 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A HHH PF00633.23 EMR72314.1 - 0.36 10.8 2.9 28 4.8 0.2 3.3 4 0 0 4 4 4 0 Helix-hairpin-helix motif ZapB PF06005.12 EMR72315.1 - 0.017 15.5 1.3 0.017 15.5 1.3 3.4 3 1 1 4 4 4 0 Cell division protein ZapB MqsA_antitoxin PF15731.5 EMR72315.1 - 0.39 10.8 0.0 0.39 10.8 0.0 2.3 3 0 0 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA TFIIA PF03153.13 EMR72315.1 - 4.5 7.2 47.5 0.73 9.8 25.9 2.1 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit A_deaminase PF00962.22 EMR72316.1 - 7.1e-50 170.2 0.0 8.3e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 EMR72316.1 - 0.0088 15.4 0.0 0.032 13.5 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Pyridoxal_deC PF00282.19 EMR72317.1 - 4.1e-76 256.1 0.0 5.2e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Abhydrolase_6 PF12697.7 EMR72318.1 - 3.3e-18 67.1 0.1 4.2e-18 66.8 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR72318.1 - 1.3e-05 24.6 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EMR72318.1 - 0.00027 19.9 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EMR72318.1 - 0.0036 17.0 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EMR72318.1 - 0.036 13.1 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 EMR72318.1 - 0.08 12.7 0.1 0.19 11.5 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family FMN_dh PF01070.18 EMR72319.1 - 1.7e-80 270.7 0.1 4.9e-45 154.1 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EMR72319.1 - 0.00025 20.3 0.1 0.0011 18.2 0.1 1.8 1 1 1 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 EMR72319.1 - 0.0075 15.3 0.1 0.016 14.2 0.1 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMR72319.1 - 0.029 13.8 0.3 0.076 12.4 0.0 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase DHO_dh PF01180.21 EMR72319.1 - 0.14 11.3 0.1 0.43 9.7 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Abhydrolase_1 PF00561.20 EMR72320.1 - 1.4e-17 64.2 0.0 1.6e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold TauD PF02668.16 EMR72321.1 - 6.9e-16 58.8 0.1 1e-15 58.3 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.22 EMR72322.1 - 1.3e-82 278.0 0.0 1.6e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mannosidase_ig PF17786.1 EMR72324.1 - 1.2e-17 64.2 0.1 4.8e-17 62.3 0.1 2.1 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EMR72324.1 - 3.8e-07 30.7 0.3 6.7e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 EMR72324.1 - 1.5e-05 24.6 0.0 5.1e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 EMR72324.1 - 0.0011 18.1 0.0 0.0027 16.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF3533 PF12051.8 EMR72325.1 - 5.9e-99 331.5 14.3 8.4e-99 331.0 14.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) EthD PF07110.11 EMR72327.1 - 2.6e-05 25.3 0.0 0.00011 23.2 0.0 2.0 1 1 0 1 1 1 1 EthD domain AA_permease_2 PF13520.6 EMR72328.1 - 2.6e-54 184.7 34.6 4.9e-41 141.0 17.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 EMR72328.1 - 2e-14 53.0 27.5 6e-09 35.0 16.3 2.2 2 0 0 2 2 2 2 Amino acid permease Tetraspanin PF00335.20 EMR72328.1 - 9.1 5.9 10.5 0.45 10.2 4.3 1.9 1 1 0 2 2 2 0 Tetraspanin family Mitofilin PF09731.9 EMR72329.1 - 0.0029 16.5 1.5 0.0031 16.4 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein HET PF06985.11 EMR72330.1 - 1.4e-34 119.5 0.0 4.1e-34 118.0 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C12 PF01088.21 EMR72331.1 - 2.6e-46 158.0 0.0 3e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AICARFT_IMPCHas PF01808.18 EMR72332.1 - 1.1e-92 310.7 0.0 1.4e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EMR72332.1 - 1.4e-23 82.8 0.0 2.6e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Clr5 PF14420.6 EMR72333.1 - 2.4e-21 75.7 2.2 4.2e-21 74.9 2.2 1.4 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 EMR72333.1 - 4.9e-08 33.1 5.1 3.4e-05 24.1 1.6 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMR72333.1 - 5.8e-06 26.0 2.2 0.0023 17.7 0.7 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMR72333.1 - 0.00022 21.7 2.6 0.29 11.7 0.5 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMR72333.1 - 0.043 13.9 2.6 16 5.9 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Tagatose_6_P_K PF08013.11 EMR72333.1 - 0.054 12.2 0.1 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Tagatose 6 phosphate kinase TPR_20 PF14561.6 EMR72333.1 - 0.057 13.8 0.0 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR72333.1 - 1.1 10.3 12.2 3.6 8.7 1.7 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR72333.1 - 2.6 8.9 0.0 2.6 8.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMR72333.1 - 4.4 8.0 10.7 3.1e+02 2.1 0.0 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat SKI PF01202.22 EMR72334.1 - 2.2e-11 44.1 0.0 3e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 EMR72334.1 - 2.7e-10 40.6 0.0 3.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMR72334.1 - 3.4e-09 37.3 0.0 3.3e-08 34.2 0.0 2.5 1 1 1 2 2 1 1 AAA domain AAA_17 PF13207.6 EMR72334.1 - 5.7e-06 26.8 0.0 1.4e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EMR72334.1 - 1.4e-05 24.9 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_16 PF13191.6 EMR72334.1 - 6.7e-05 23.3 0.0 9.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EMR72334.1 - 0.00012 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EMR72334.1 - 0.00018 22.0 0.0 0.00031 21.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EMR72334.1 - 0.00047 20.1 0.0 0.00092 19.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMR72334.1 - 0.0006 20.1 0.0 0.00096 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMR72334.1 - 0.0028 17.7 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EMR72334.1 - 0.0031 17.8 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMR72334.1 - 0.0037 17.6 0.0 0.0072 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase dNK PF01712.19 EMR72334.1 - 0.0054 16.6 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase Cytidylate_kin2 PF13189.6 EMR72334.1 - 0.0068 16.6 0.0 0.037 14.2 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase-like family Mg_chelatase PF01078.21 EMR72334.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EMR72334.1 - 0.014 15.5 0.0 0.034 14.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EMR72334.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 EMR72334.1 - 0.019 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase T2SSE PF00437.20 EMR72334.1 - 0.019 14.1 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EMR72334.1 - 0.036 14.0 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PRK PF00485.18 EMR72334.1 - 0.037 13.8 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 EMR72334.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 EMR72334.1 - 0.061 13.6 0.2 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EMR72334.1 - 0.068 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EMR72334.1 - 0.077 13.5 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 EMR72334.1 - 0.082 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 EMR72334.1 - 0.091 12.9 0.0 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase AAA_7 PF12775.7 EMR72334.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EMR72334.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EMR72334.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Thermopsin PF05317.11 EMR72334.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Thermopsin RuvB_N PF05496.12 EMR72334.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta2 PF13177.6 EMR72334.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase III, delta subunit CobU PF02283.16 EMR72334.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_25 PF13481.6 EMR72334.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMR72334.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EMR72334.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 KaiC PapD_N PF00345.20 EMR72335.1 - 0.073 13.0 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain zf-MYND PF01753.18 EMR72336.1 - 1.6e-09 37.7 17.1 2.6e-09 37.0 17.1 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EMR72336.1 - 2.5 8.5 11.6 5.1 7.5 11.6 1.5 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SUN PF03856.13 EMR72337.1 - 8.7e-90 300.5 9.9 1.2e-89 300.0 9.9 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) TMEM171 PF15471.6 EMR72337.1 - 0.3 10.0 6.1 0.47 9.4 6.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 EF1_GNE PF00736.19 EMR72338.1 - 5.7e-34 116.2 2.9 9.8e-34 115.4 2.9 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EMR72338.1 - 3.7e-15 56.1 6.4 3.7e-15 56.1 6.4 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 EMR72338.1 - 0.00058 20.0 0.2 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMR72338.1 - 0.0023 18.1 1.1 0.012 15.8 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.14 EMR72339.1 - 2.3e-43 148.3 0.0 1.2e-42 145.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EMR72339.1 - 1.7e-36 124.3 1.8 1.7e-36 124.3 1.8 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EMR72339.1 - 4e-26 90.9 0.3 4e-26 90.9 0.3 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EMR72339.1 - 7.8e-19 68.4 0.0 4.8e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMR72339.1 - 1.2e-12 48.0 0.1 1e-08 35.2 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMR72339.1 - 6.4e-09 36.4 8.5 0.0016 18.8 0.7 4.3 3 2 0 3 3 2 2 AAA ATPase domain Sigma54_activat PF00158.26 EMR72339.1 - 1.8e-07 31.0 0.2 0.00023 20.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EMR72339.1 - 6.6e-07 29.7 4.2 0.029 14.7 0.0 3.8 3 2 0 3 3 2 2 AAA domain TniB PF05621.11 EMR72339.1 - 5.1e-06 26.0 0.0 0.0034 16.8 0.1 3.6 3 1 0 3 3 2 1 Bacterial TniB protein NACHT PF05729.12 EMR72339.1 - 1e-05 25.6 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 EMR72339.1 - 3.6e-05 23.8 0.0 0.46 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EMR72339.1 - 4.5e-05 23.1 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EMR72339.1 - 0.00014 21.6 0.1 0.44 10.3 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 EMR72339.1 - 0.00026 21.0 6.5 0.45 10.4 0.2 4.1 3 2 1 4 4 3 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EMR72339.1 - 0.0021 18.6 0.8 1.1 9.8 0.0 3.4 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.22 EMR72339.1 - 0.0024 18.3 0.0 0.39 11.1 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EMR72339.1 - 0.0024 17.6 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMR72339.1 - 0.0036 17.6 0.3 6.1 7.1 0.0 3.7 4 0 0 4 4 3 0 AAA domain Roc PF08477.13 EMR72339.1 - 0.0037 17.5 0.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ERM PF00769.19 EMR72339.1 - 0.0039 17.0 9.4 0.0066 16.3 9.4 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_18 PF13238.6 EMR72339.1 - 0.0049 17.4 5.0 0.095 13.2 0.0 3.6 4 1 0 4 4 3 1 AAA domain AAA_30 PF13604.6 EMR72339.1 - 0.0055 16.4 0.1 0.51 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EMR72339.1 - 0.0057 16.1 0.2 2.8 7.3 0.0 3.3 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EMR72339.1 - 0.006 16.5 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 EMR72339.1 - 0.0072 16.0 0.0 0.29 10.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TsaE PF02367.17 EMR72339.1 - 0.0075 16.3 0.0 3.7 7.6 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EMR72339.1 - 0.012 15.7 0.0 7.2 6.6 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EMR72339.1 - 0.017 14.6 0.0 0.57 9.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 EMR72339.1 - 0.022 14.3 0.2 1 8.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMR72339.1 - 0.029 14.5 0.0 15 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EMR72339.1 - 0.033 14.5 1.4 1.1 9.6 0.1 3.2 2 2 0 2 2 2 0 AAA domain DUF815 PF05673.13 EMR72339.1 - 0.034 13.3 0.3 1.9 7.6 0.2 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EMR72339.1 - 0.058 12.7 0.0 1.6 8.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 EMR72339.1 - 0.073 12.8 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EMR72339.1 - 0.082 12.8 0.0 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 NTPase DUF4407 PF14362.6 EMR72339.1 - 0.099 12.0 4.0 0.16 11.3 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIF1 PF05970.14 EMR72339.1 - 0.12 11.6 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase AAA_29 PF13555.6 EMR72339.1 - 0.12 12.2 0.1 5.6 6.8 0.0 2.6 3 0 0 3 3 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 EMR72339.1 - 0.13 12.0 0.1 0.82 9.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF1640 PF07798.11 EMR72339.1 - 0.13 12.3 7.5 0.27 11.3 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_21 PF13304.6 EMR72339.1 - 0.17 11.6 1.8 2.7 7.7 0.1 3.3 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system UvrD-helicase PF00580.21 EMR72339.1 - 0.2 11.1 2.4 0.74 9.3 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain UPF0242 PF06785.11 EMR72339.1 - 0.29 11.2 7.6 0.79 9.8 7.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS2 PF15003.6 EMR72339.1 - 0.53 10.0 8.0 0.37 10.5 2.3 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 OEP PF02321.18 EMR72339.1 - 1.4 8.7 10.4 3.3 7.5 10.4 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein DUF4795 PF16043.5 EMR72339.1 - 2.3 7.7 11.2 51 3.4 8.5 3.4 3 1 0 3 3 2 0 Domain of unknown function (DUF4795) CENP-F_leu_zip PF10473.9 EMR72339.1 - 3.2 7.8 18.3 0.97 9.4 11.5 2.6 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 EMR72339.1 - 4.7 7.5 15.0 2.1 8.6 10.5 2.8 3 0 0 3 3 1 0 Seryl-tRNA synthetase N-terminal domain DUF4061 PF13270.6 EMR72339.1 - 4.7 7.6 9.5 60 4.0 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) cNMP_binding PF00027.29 EMR72340.1 - 4.9e-17 61.8 0.0 6.3e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ribosomal_S19 PF00203.21 EMR72341.1 - 1.6e-33 114.4 0.2 2.2e-33 114.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Peptidase_M49 PF03571.15 EMR72342.1 - 9e-242 803.3 0.0 1.1e-241 803.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF2263 PF10021.9 EMR72344.1 - 1e-17 64.9 0.0 2.8e-17 63.4 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 EMR72344.1 - 0.003 17.6 0.1 0.76 9.8 0.0 2.7 2 1 0 2 2 2 1 Macro domain DUF3530 PF12048.8 EMR72344.1 - 0.021 14.2 0.4 6.9 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) DUF2076 PF09849.9 EMR72344.1 - 0.11 12.6 19.3 0.12 12.4 1.5 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) Coilin_N PF15862.5 EMR72344.1 - 2.1 8.1 6.2 0.48 10.2 1.6 2.2 2 0 0 2 2 2 0 Coilin N-terminus Sporozoite_P67 PF05642.11 EMR72344.1 - 6.6 4.7 9.7 0.06 11.4 1.0 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen MRP PF09387.10 EMR72345.1 - 0.049 13.6 0.1 0.069 13.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Cmyb_C PF09316.10 EMR72345.1 - 0.18 11.5 3.2 0.095 12.4 1.0 1.6 2 0 0 2 2 2 0 C-myb, C-terminal GCV_T PF01571.21 EMR72346.1 - 5.4e-84 281.6 0.0 6.7e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EMR72346.1 - 3.9e-24 84.4 0.3 8.3e-24 83.3 0.3 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain EMP24_GP25L PF01105.24 EMR72347.1 - 6.5e-46 156.6 0.1 7.4e-46 156.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1408 PF07193.11 EMR72347.1 - 0.089 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) BING4CT PF08149.11 EMR72348.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 BING4CT (NUC141) domain DUF3659 PF12396.8 EMR72350.1 - 0.0069 16.3 0.3 0.0069 16.3 0.3 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3659) DUF1387 PF07139.11 EMR72350.1 - 0.11 12.2 2.5 0.15 11.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Dsh_C PF12316.8 EMR72350.1 - 2.1 8.7 7.0 2.7 8.3 7.0 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RhlB PF12300.8 EMR72350.1 - 2.9 8.0 11.7 4.4 7.4 11.7 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Proteasom_Rpn13 PF04683.13 EMR72351.1 - 1.4e-26 92.8 0.0 2.2e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EMR72351.1 - 3.3e-09 36.9 0.4 3.8e-08 33.5 0.4 2.2 1 1 0 1 1 1 1 UCH-binding domain L27_2 PF09045.10 EMR72351.1 - 0.15 12.0 0.2 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 L27_2 RRM_1 PF00076.22 EMR72352.1 - 1.8e-12 46.9 0.0 2.6e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMR72352.1 - 0.023 14.8 0.1 0.069 13.3 0.0 1.7 1 1 1 2 2 2 0 RNA recognition motif CDC45 PF02724.14 EMR72352.1 - 2.4 6.4 10.5 0.38 9.0 2.7 2.6 3 0 0 3 3 3 0 CDC45-like protein DUF2967 PF11179.8 EMR72352.1 - 4.3 5.3 15.5 0.51 8.4 10.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) 3-HAO PF06052.12 EMR72353.1 - 2e-66 222.3 0.0 2.3e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EMR72353.1 - 8.3e-07 28.6 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EMR72353.1 - 7.6e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DZR PF12773.7 EMR72353.1 - 0.0013 18.8 2.2 0.0023 17.9 2.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon Cupin_1 PF00190.22 EMR72353.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Cupin C1_1 PF00130.22 EMR72353.1 - 0.008 16.0 1.2 0.34 10.8 0.2 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 EMR72353.1 - 0.018 15.1 1.3 0.031 14.4 1.3 1.3 1 0 0 1 1 1 0 FYVE zinc finger Nudix_N_2 PF14803.6 EMR72353.1 - 0.045 13.7 1.2 0.76 9.7 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal C1_2 PF03107.16 EMR72353.1 - 0.071 13.4 0.3 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 C1 domain zf-ACC PF17848.1 EMR72353.1 - 0.071 13.2 1.1 3.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain ARD PF03079.14 EMR72353.1 - 0.075 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family TF_Zn_Ribbon PF08271.12 EMR72353.1 - 0.08 12.5 0.3 12 5.5 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding ADK_lid PF05191.14 EMR72353.1 - 0.19 11.7 4.2 0.13 12.3 1.7 2.1 2 1 0 2 2 2 0 Adenylate kinase, active site lid HalOD2 PF18547.1 EMR72353.1 - 0.31 11.0 2.2 7 6.6 0.9 2.4 2 1 0 2 2 2 0 Halobacterial output domain 2 Zn-ribbon_8 PF09723.10 EMR72353.1 - 0.46 10.6 5.3 13 6.0 5.3 2.3 1 1 0 1 1 1 0 Zinc ribbon domain Arf PF00025.21 EMR72354.1 - 1.5e-79 265.5 0.2 1.7e-79 265.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMR72354.1 - 1.7e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMR72354.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EMR72354.1 - 2.7e-13 49.8 1.4 2.2e-09 36.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EMR72354.1 - 3.4e-13 49.5 0.0 3.8e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EMR72354.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMR72354.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EMR72354.1 - 0.01 15.2 1.0 0.03 13.6 1.0 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Ribosomal_L6e PF01159.19 EMR72355.1 - 4e-39 133.6 0.4 4e-39 133.6 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e Sld5 PF05916.11 EMR72356.1 - 7.3e-12 45.7 0.0 9.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 EMR72356.1 - 0.12 13.2 0.0 0.33 11.8 0.0 1.7 1 0 0 1 1 1 0 Flagellar protein FliT DUF3405 PF11885.8 EMR72357.1 - 6.3e-228 757.6 4.2 7.4e-228 757.3 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Polysacc_deac_1 PF01522.21 EMR72359.1 - 2e-28 98.8 0.0 3.4e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EMR72359.1 - 3.7e-18 65.7 42.7 2.7e-09 37.4 22.0 2.6 2 0 0 2 2 2 2 Chitin recognition protein CENP-B_dimeris PF09026.10 EMR72359.1 - 0.005 17.2 8.7 0.0091 16.4 8.7 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF2457 PF10446.9 EMR72359.1 - 6.4 5.8 7.4 9.4 5.3 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.25 EMR72360.1 - 4.1e-46 157.5 0.2 6.2e-46 156.9 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR72360.1 - 5e-26 91.5 0.0 7.3e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EMR72360.1 - 4.3e-08 33.4 0.2 1.1e-07 32.1 0.2 1.8 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EMR72360.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Yop-YscD_cpl PF16697.5 EMR72360.1 - 0.053 13.8 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain SPT2 PF08243.11 EMR72362.1 - 5.2e-10 39.8 26.3 2.3e-08 34.5 12.1 2.3 1 1 1 2 2 2 2 SPT2 chromatin protein PBP1_TM PF14812.6 EMR72362.1 - 0.018 15.4 7.1 0.018 15.4 7.1 2.8 2 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Importin_rep_6 PF18829.1 EMR72362.1 - 4.2 7.5 6.4 7.9 6.7 6.4 1.4 1 0 0 1 1 1 0 Importin repeat 6 Ribosomal_S8e PF01201.22 EMR72363.1 - 6.2e-45 152.7 0.8 1.2e-44 151.8 0.8 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e DUF4050 PF13259.6 EMR72363.1 - 0.14 12.5 2.8 0.21 11.9 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Pannexin_like PF12534.8 EMR72363.1 - 1 8.4 6.4 1.4 8.0 6.4 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Ammonium_transp PF00909.21 EMR72364.1 - 3.1e-102 342.3 20.4 3.7e-102 342.0 20.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family WH2 PF02205.20 EMR72366.1 - 5.2e-10 38.8 3.1 2.9e-09 36.5 0.7 2.5 2 0 0 2 2 2 1 WH2 motif DUF1989 PF09347.10 EMR72367.1 - 1.3e-64 216.8 0.0 1.6e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Ribosomal_L21p PF00829.21 EMR72368.1 - 4.7e-10 39.6 0.0 6.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein RNA_pol_Rbc25 PF08292.12 EMR72369.1 - 7.7e-31 107.0 3.7 1.4e-30 106.1 2.5 2.0 2 1 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EMR72369.1 - 1e-15 57.8 0.0 1.7e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EMR72369.1 - 0.00052 20.3 0.0 0.0012 19.2 0.0 1.6 1 1 0 1 1 1 1 S1 RNA binding domain DNA_ligase_A_M PF01068.21 EMR72369.1 - 0.011 15.3 0.0 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 ATP dependent DNA ligase domain S1_2 PF13509.6 EMR72369.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 S1 domain Coiled-coil_56 PF09813.9 EMR72370.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 EMC3_TMCO1 PF01956.16 EMR72372.1 - 8e-53 178.6 1.4 1.1e-52 178.2 1.4 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF3347 PF11827.8 EMR72373.1 - 0.052 13.7 1.5 0.079 13.1 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) F-box PF00646.33 EMR72374.1 - 0.00029 20.6 0.0 0.00073 19.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMR72374.1 - 0.026 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 EMR72375.1 - 3.7e-46 157.6 0.0 1.7e-34 119.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR72375.1 - 5.8e-18 65.1 0.0 2.1e-16 60.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMR72375.1 - 0.00074 19.5 0.9 0.6 10.0 0.1 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family PsaA_PsaB PF00223.19 EMR72375.1 - 0.062 11.5 0.0 0.089 11.0 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein RIO1 PF01163.22 EMR72375.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.7 EMR72376.1 - 4.7e-05 23.2 0.1 0.00015 21.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR72376.1 - 0.0021 17.9 0.0 0.0065 16.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain SPC25 PF06703.11 EMR72377.1 - 1e-50 171.7 0.0 1.2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RPN7 PF10602.9 EMR72377.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF3734 PF12536.8 EMR72378.1 - 0.035 14.5 1.2 0.035 14.5 1.2 2.5 2 1 0 2 2 2 0 Patatin phospholipase P4Ha_N PF08336.11 EMR72378.1 - 0.86 9.6 13.4 0.16 12.0 1.4 2.8 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2894 PF11445.8 EMR72378.1 - 5.7 7.4 12.9 99 3.3 12.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) DUF948 PF06103.11 EMR72378.1 - 8.1 6.8 9.0 63 3.9 0.0 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Tubulin PF00091.25 EMR72379.1 - 2.6e-62 210.5 0.0 3.5e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMR72379.1 - 5.4e-45 152.6 0.0 8.3e-45 152.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EMR72379.1 - 7.5e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MMS19_C PF12460.8 EMR72380.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.4 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal WW PF00397.26 EMR72381.1 - 7.9e-11 41.9 5.5 1.8e-10 40.7 5.5 1.7 1 0 0 1 1 1 1 WW domain LIN37 PF15306.6 EMR72381.1 - 0.32 11.2 3.9 0.66 10.2 3.9 1.5 1 0 0 1 1 1 0 LIN37 B277 PF17623.2 EMR72381.1 - 2.5 7.1 3.3 3.7 6.5 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function Sds3 PF08598.11 EMR72382.1 - 3.7e-19 69.6 5.4 3.7e-19 69.6 5.4 2.1 2 1 0 2 2 2 1 Sds3-like TMEM247 PF15444.6 EMR72382.1 - 0.29 11.2 2.3 0.63 10.0 2.3 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 THF_DHG_CYH PF00763.23 EMR72383.1 - 4.3e-26 91.5 0.1 6.4e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EMR72383.1 - 2e-12 46.7 0.0 1.7e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.22 EMR72383.1 - 0.014 14.4 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle NUFIP1 PF10453.9 EMR72384.1 - 6.4e-06 25.9 1.7 6.4e-06 25.9 1.7 2.2 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 EMR72384.1 - 0.0053 16.8 8.7 0.0091 16.0 8.7 1.4 1 0 0 1 1 1 1 Zinc finger domain 7TM_GPCR_Srx PF10328.9 EMR72384.1 - 0.036 13.7 0.8 0.061 12.9 0.8 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx zf-CCCH_2 PF14608.6 EMR72384.1 - 0.087 13.3 5.0 0.16 12.5 5.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 EMR72384.1 - 0.11 12.4 5.8 0.18 11.8 5.8 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EMR72384.1 - 0.12 12.2 8.4 0.3 10.9 8.4 1.7 1 1 0 1 1 1 0 CCCH-type zinc finger zf-C3H1 PF10650.9 EMR72384.1 - 0.28 10.9 1.2 0.48 10.2 1.2 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain UPF0182 PF03699.13 EMR72384.1 - 0.39 8.8 2.6 0.54 8.3 2.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Apc15p PF05841.11 EMR72384.1 - 0.41 11.4 5.8 1.2 10.0 4.8 2.3 1 1 0 1 1 1 0 Apc15p protein Snapin_Pallidin PF14712.6 EMR72384.1 - 1.1 9.7 4.9 2 8.9 4.9 1.4 1 0 0 1 1 1 0 Snapin/Pallidin AIM3 PF17096.5 EMR72384.1 - 4.8 8.2 10.6 0.86 10.6 6.1 2.2 2 1 0 2 2 2 0 Altered inheritance of mitochondria protein 3 RseC_MucC PF04246.12 EMR72384.1 - 8 6.4 15.2 0.12 12.3 1.9 3.5 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.16 EMR72385.1 - 5.8e-28 97.8 30.6 5.8e-28 97.8 30.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CHORD PF04968.12 EMR72386.1 - 2.7e-48 162.5 20.5 4.6e-25 88.1 5.6 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 EMR72386.1 - 2.9e-11 44.2 0.0 4.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 CS domain Ribosomal_60s PF00428.19 EMR72387.1 - 3e-26 91.8 12.5 3.4e-26 91.6 12.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 EMR72387.1 - 0.01 16.2 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain MccV PF17508.2 EMR72387.1 - 0.022 15.3 1.2 0.03 14.9 1.2 1.2 1 0 0 1 1 1 0 Microcin V bacteriocin RibD_C PF01872.17 EMR72387.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain DUF2967 PF11179.8 EMR72387.1 - 1.9 6.5 5.1 1.7 6.6 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Transp_cyt_pur PF02133.15 EMR72388.1 - 7e-121 404.1 30.1 6.4e-98 328.4 15.1 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin PARP PF00644.20 EMR72389.1 - 1.5e-58 197.6 0.0 3.8e-58 196.3 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EMR72389.1 - 2.9e-44 150.5 0.9 5.4e-44 149.6 0.9 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EMR72389.1 - 1.2e-22 79.8 0.2 2.9e-22 78.5 0.2 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 EMR72389.1 - 7.2e-10 39.1 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EMR72389.1 - 8.8e-06 25.6 0.1 2.3e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EMR72389.1 - 0.00013 22.3 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EMR72389.1 - 0.017 15.4 0.1 0.04 14.2 0.1 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EMR72389.1 - 0.034 14.2 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF5523 PF17661.1 EMR72389.1 - 0.93 9.1 7.7 0.42 10.3 2.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) HpcH_HpaI PF03328.14 EMR72390.1 - 1.6e-25 89.5 0.0 2e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Cys_Met_Meta_PP PF01053.20 EMR72391.1 - 3.6e-139 463.5 0.0 4.2e-139 463.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMR72391.1 - 3.7e-07 29.4 0.7 6.6e-07 28.6 0.3 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMR72391.1 - 1.8e-06 27.4 0.1 2.7e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMR72391.1 - 0.00011 21.7 0.3 0.00018 20.9 0.3 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EMR72391.1 - 0.00085 18.7 0.4 0.0017 17.7 0.5 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase RRM_1 PF00076.22 EMR72392.1 - 1.7e-12 46.9 0.2 4e-08 33.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 EMR72392.1 - 1.1 7.5 18.6 1.6 6.9 18.6 1.2 1 0 0 1 1 1 0 CDC45-like protein KH_1 PF00013.29 EMR72393.1 - 9.8e-41 137.4 11.2 1.1e-15 57.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EMR72393.1 - 1.3e-09 37.8 9.5 0.016 15.0 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EMR72393.1 - 1e-08 34.9 4.3 0.011 15.6 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EMR72393.1 - 8.8e-05 22.5 6.1 0.25 11.4 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 EMR72393.1 - 0.019 14.9 0.0 14 5.8 0.0 3.0 3 0 0 3 3 3 0 KH-like RNA-binding domain UAA PF08449.11 EMR72394.1 - 2.3e-39 135.4 5.5 4.1e-39 134.6 5.5 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EMR72394.1 - 8.6e-10 38.9 23.3 7.4e-06 26.2 7.3 3.4 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EMR72394.1 - 3.4e-05 23.2 0.3 0.0041 16.3 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 EMR72394.1 - 0.0024 16.9 2.9 0.89 8.4 0.0 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EMR72394.1 - 0.046 13.1 7.8 0.72 9.1 1.3 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2681 PF10883.8 EMR72394.1 - 2.5 8.5 5.0 2.7 8.5 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF5381 PF17353.2 EMR72394.1 - 3 7.6 5.0 6.5 6.5 0.0 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5381) Myb_DNA-binding PF00249.31 EMR72395.1 - 1.5e-15 57.1 2.3 1.3e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR72395.1 - 1.1e-06 28.8 3.7 0.0012 19.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain GFO_IDH_MocA PF01408.22 EMR72396.1 - 2.5e-18 67.0 0.2 4.6e-18 66.2 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EMR72396.1 - 8e-05 23.3 0.1 0.00014 22.4 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OpuAC PF04069.12 EMR72396.1 - 0.073 12.6 0.0 1.2 8.6 0.0 2.7 2 1 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system DXP_reductoisom PF02670.16 EMR72396.1 - 0.076 13.7 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Aldo_ket_red PF00248.21 EMR72397.1 - 2.9e-14 53.0 0.0 4.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family CAP_GLY PF01302.25 EMR72398.1 - 1.1e-21 76.6 2.5 1.7e-21 76.0 2.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EMR72398.1 - 1.1e-17 64.3 0.0 1.6e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain PhoD PF09423.10 EMR72398.1 - 0.15 11.0 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase Methyltransf_12 PF08242.12 EMR72399.1 - 0.00021 22.0 0.4 0.17 12.6 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EMR72399.1 - 0.00051 19.9 0.0 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMR72399.1 - 0.013 15.3 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EMR72399.1 - 0.015 16.0 0.3 0.093 13.4 0.3 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EMR72399.1 - 0.093 13.4 0.5 1.6 9.5 0.5 2.3 1 1 0 1 1 1 0 Methyltransferase domain TRI12 PF06609.13 EMR72400.1 - 3.4e-08 32.4 2.1 4.2e-08 32.1 2.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Spore_GerQ PF09671.10 EMR72401.1 - 0.099 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) CorA PF01544.18 EMR72403.1 - 5.8e-05 22.5 3.9 9.2e-05 21.9 0.0 3.0 4 0 0 4 4 4 1 CorA-like Mg2+ transporter protein DUF755 PF05501.11 EMR72403.1 - 0.036 14.3 0.8 6.3 7.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) IL32 PF15225.6 EMR72403.1 - 0.094 13.1 0.0 0.35 11.3 0.0 2.0 1 0 0 1 1 1 0 Interleukin 32 Pkinase PF00069.25 EMR72406.1 - 3.1e-68 230.0 0.0 5.9e-68 229.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR72406.1 - 9.2e-48 162.8 0.0 1.8e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EMR72406.1 - 1e-27 96.4 0.0 2e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 EMR72406.1 - 5.8e-18 64.8 0.1 1.3e-17 63.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EMR72406.1 - 1.6e-16 60.5 0.1 3e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EMR72406.1 - 8.6e-14 51.9 0.0 1.6e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 EMR72406.1 - 7.3e-07 28.8 0.0 0.00054 19.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.16 EMR72406.1 - 0.00019 21.3 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_4 PF18017.1 EMR72406.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 EMR72406.1 - 0.071 11.9 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SAM_Ste50p PF09235.10 EMR72406.1 - 0.11 12.8 0.3 0.28 11.5 0.3 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif MRP-L51 PF10244.9 EMR72406.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit IlvC PF01450.19 EMR72406.1 - 0.15 12.3 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_3 PF01494.19 EMR72407.1 - 3e-17 62.9 2.1 8.9e-16 58.1 2.1 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMR72407.1 - 1.6e-05 25.0 0.0 3.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR72407.1 - 0.0078 15.8 0.1 0.035 13.7 0.0 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR72407.1 - 0.011 15.0 0.0 0.025 13.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR72407.1 - 0.031 14.8 0.0 0.085 13.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box PF00646.33 EMR72408.1 - 1.7 8.6 5.9 5.7 6.9 0.3 3.0 3 0 0 3 3 3 0 F-box domain DNA_ligase_A_M PF01068.21 EMR72409.1 - 2.3e-52 177.6 1.2 1e-39 136.3 0.3 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EMR72409.1 - 7.4e-45 153.4 0.0 1.6e-44 152.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EMR72409.1 - 2.8e-29 101.6 0.6 1.1e-28 99.8 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EMR72409.1 - 0.0001 22.6 0.3 0.00019 21.7 0.3 1.4 1 0 0 1 1 1 1 RNA ligase Mitofilin PF09731.9 EMR72409.1 - 9 5.0 30.7 21 3.8 30.7 1.5 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ECH_1 PF00378.20 EMR72410.1 - 1.4e-74 250.6 0.1 1.7e-74 250.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMR72410.1 - 3.1e-38 132.1 0.1 2.3e-35 122.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Hydrolase PF00702.26 EMR72410.1 - 0.038 14.3 0.1 0.15 12.3 0.0 1.8 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase SH3_9 PF14604.6 EMR72411.1 - 5.9e-06 26.0 0.1 5.9e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EMR72411.1 - 8e-05 22.2 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMR72411.1 - 0.0066 16.1 0.6 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Ribosomal_L23eN PF03939.13 EMR72412.1 - 5.7e-25 87.3 7.2 5.7e-25 87.3 7.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EMR72412.1 - 2.6e-17 62.9 0.5 5.6e-17 61.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 TusA PF01206.17 EMR72412.1 - 0.1 12.4 0.1 0.69 9.8 0.1 2.1 2 0 0 2 2 2 0 Sulfurtransferase TusA ABC_tran PF00005.27 EMR72413.1 - 4.6e-33 114.6 0.0 7.1e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 EMR72413.1 - 0.002 17.4 0.1 0.004 16.5 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.6 EMR72413.1 - 0.0037 17.1 0.0 0.0075 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMR72413.1 - 0.0038 17.1 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EMR72413.1 - 0.0073 16.0 1.0 0.12 12.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EMR72413.1 - 0.0093 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ptaRNA1_toxin PF12703.7 EMR72413.1 - 0.012 15.6 0.1 0.032 14.3 0.1 1.7 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system ABC_membrane PF00664.23 EMR72413.1 - 0.019 14.6 1.0 0.019 14.6 1.0 1.6 1 1 0 1 1 1 0 ABC transporter transmembrane region AAA_29 PF13555.6 EMR72413.1 - 0.024 14.4 0.5 0.054 13.3 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 EMR72413.1 - 0.032 13.7 0.0 0.75 9.2 0.0 2.1 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EMR72413.1 - 0.039 13.5 0.1 0.3 10.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EMR72413.1 - 0.091 13.3 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EMR72413.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 EMR72413.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.7 EMR72413.1 - 0.14 11.1 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 EMR72413.1 - 0.15 12.3 0.2 0.69 10.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EMR72413.1 - 0.18 12.0 3.7 0.66 10.2 0.5 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MerE PF05052.12 EMR72413.1 - 0.19 11.7 0.4 0.46 10.4 0.4 1.7 1 0 0 1 1 1 0 MerE protein G-alpha PF00503.20 EMR72413.1 - 0.21 10.7 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit HET PF06985.11 EMR72414.1 - 2.1e-22 80.1 0.0 3.4e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.24 EMR72416.1 - 1.2e-25 90.2 28.8 8.5e-16 58.3 9.2 3.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 EMR72416.1 - 1.6e-15 57.5 11.5 1.6e-15 57.5 11.5 4.5 5 0 0 5 5 5 1 Inner membrane component domain Y_phosphatase PF00102.27 EMR72417.1 - 1.2e-61 208.3 0.0 1.9e-34 119.3 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EMR72417.1 - 0.0095 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EMR72417.1 - 0.016 15.0 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain OB_NTP_bind PF07717.16 EMR72418.1 - 1e-22 80.3 0.1 5.9e-22 77.8 0.1 2.3 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EMR72418.1 - 3e-16 59.7 0.0 7.7e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMR72418.1 - 1.7e-11 44.4 0.0 8.7e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMR72418.1 - 3.1e-08 33.6 0.1 8.5e-08 32.2 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMR72418.1 - 8e-07 29.4 0.0 2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EMR72418.1 - 9.2e-05 22.1 0.0 0.00027 20.6 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EMR72418.1 - 0.0027 18.3 0.0 0.0061 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EMR72418.1 - 0.006 16.6 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 EMR72418.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR72418.1 - 0.0096 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EMR72418.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_I1 PF03289.13 EMR72418.1 - 0.013 14.7 0.3 0.023 13.8 0.3 1.4 1 0 0 1 1 1 0 Poxvirus protein I1 ResIII PF04851.15 EMR72418.1 - 0.013 15.5 0.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Amidase PF01425.21 EMR72419.1 - 2.6e-57 194.8 0.0 2.6e-56 191.5 0.0 1.9 1 1 0 1 1 1 1 Amidase COesterase PF00135.28 EMR72420.1 - 2.1e-81 274.4 0.0 1.2e-72 245.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR72420.1 - 2.7e-11 43.7 0.0 4.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR72420.1 - 0.1 13.2 4.9 0.19 12.3 4.9 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family ANAPC10 PF03256.16 EMR72421.1 - 2.2e-48 164.4 0.0 3.1e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Ras PF00071.22 EMR72422.1 - 2.1e-21 76.2 0.0 3.5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMR72422.1 - 2.7e-05 24.4 0.0 6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NPV_P10 PF05531.12 EMR72422.1 - 0.1 13.1 3.0 9.4 6.8 0.1 3.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GATase PF00117.28 EMR72423.1 - 4.3e-08 33.2 0.0 7.7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I adh_short_C2 PF13561.6 EMR72424.1 - 2.7e-41 141.7 0.0 2.3e-25 89.5 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR72424.1 - 2.7e-35 121.6 0.0 1.8e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Ribosomal_60s PF00428.19 EMR72424.1 - 0.023 15.3 3.2 0.033 14.8 1.5 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein BSP_II PF05432.11 EMR72424.1 - 1.5 8.4 9.1 2.8 7.6 9.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DHR-2 PF06920.13 EMR72425.1 - 2e-33 115.9 2.8 1.1e-32 113.4 2.8 1.8 1 1 0 1 1 1 1 Dock homology region 2 GCIP PF13324.6 EMR72425.1 - 0.00097 18.8 1.4 0.0082 15.8 1.7 2.1 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting SPESP1 PF15754.5 EMR72425.1 - 0.0071 15.6 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 Cwf_Cwc_15 PF04889.12 EMR72425.1 - 0.011 15.5 2.3 0.017 14.9 2.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EMR72425.1 - 0.054 13.9 3.8 0.12 12.8 3.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LamB_YcsF PF03746.16 EMR72425.1 - 0.057 13.1 1.3 0.6 9.7 0.3 2.2 2 0 0 2 2 2 0 LamB/YcsF family NOA36 PF06524.12 EMR72425.1 - 1.1 8.5 4.1 1.7 7.9 4.1 1.2 1 0 0 1 1 1 0 NOA36 protein Sod_Fe_C PF02777.18 EMR72426.1 - 2.7e-35 120.6 0.3 5.4e-35 119.6 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMR72426.1 - 5.3e-30 103.7 1.6 1.1e-29 102.7 0.4 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain JmjC PF02373.22 EMR72427.1 - 2.7e-38 130.9 0.5 6.2e-38 129.7 0.5 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 EMR72427.1 - 5.3e-20 71.6 5.9 6.1e-20 71.4 4.4 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EMR72427.1 - 1.3e-19 70.2 5.6 2.5e-19 69.3 3.2 2.6 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 EMR72427.1 - 1.2e-13 50.8 2.0 2.7e-13 49.6 2.0 1.7 1 0 0 1 1 1 1 jmjN domain CDC45 PF02724.14 EMR72427.1 - 0.017 13.4 0.8 0.03 12.6 0.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 EMR72427.1 - 1.2 8.3 6.1 2 7.5 6.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PGA2 PF07543.12 EMR72427.1 - 4.7 7.2 13.9 0.23 11.5 7.1 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DNA_pol_phi PF04931.13 EMR72427.1 - 5.7 4.9 6.3 8.4 4.4 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi ORF11CD3 PF10549.9 EMR72429.1 - 0.2 11.8 2.8 23 5.2 0.6 2.9 3 0 0 3 3 3 0 ORF11CD3 domain Prominin PF05478.11 EMR72429.1 - 0.53 8.2 6.0 0.81 7.6 6.0 1.3 1 1 0 1 1 1 0 Prominin FlxA PF14282.6 EMR72429.1 - 1.4 9.0 22.5 5.3 7.1 17.0 3.0 2 1 0 2 2 2 0 FlxA-like protein Ima1_N PF09779.9 EMR72429.1 - 4 8.3 5.5 2.3 9.1 2.5 2.2 1 1 0 1 1 1 0 Ima1 N-terminal domain V_ATPase_I PF01496.19 EMR72429.1 - 4.7 5.0 7.4 6.2 4.6 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4404 PF14357.6 EMR72429.1 - 6.9 7.4 14.2 0.31 11.7 7.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMF_TATA_bd PF12325.8 EMR72429.1 - 9.7 6.5 19.4 0.043 14.0 7.4 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding GST_N_3 PF13417.6 EMR72430.1 - 2.2e-13 50.4 0.0 4.1e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMR72430.1 - 1.3e-11 44.7 0.1 2.4e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMR72430.1 - 1.5e-10 41.3 0.0 2.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR72430.1 - 4.9e-10 39.5 0.0 8.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMR72430.1 - 8.4e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR72430.1 - 5.2e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GDPD PF03009.17 EMR72431.1 - 6.8e-71 239.0 0.1 1.2e-69 234.9 0.0 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.6 EMR72431.1 - 3.5e-28 97.6 3.8 1.4e-10 41.5 0.1 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMR72431.1 - 2e-26 92.4 0.4 2.6e-13 50.4 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.19 EMR72431.1 - 1.7e-23 84.2 10.6 2e-11 44.5 0.1 4.0 3 1 1 4 4 4 3 SPX domain Ank_5 PF13857.6 EMR72431.1 - 2.9e-16 59.3 0.5 1.2e-05 25.5 0.0 5.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EMR72431.1 - 8.2e-15 54.5 3.1 0.00059 20.2 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EMR72431.1 - 3.2e-14 51.6 3.5 0.038 14.5 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat TraD PF06412.11 EMR72431.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Conjugal transfer protein TraD ER_lumen_recept PF00810.18 EMR72432.1 - 6e-52 176.4 7.0 9.6e-52 175.7 7.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor AAA PF00004.29 EMR72433.1 - 7.7e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMR72433.1 - 2.1e-14 53.0 0.0 4.3e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EMR72433.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMR72433.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 EMR72433.1 - 2.6e-06 27.3 4.0 7e-06 25.9 4.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EMR72433.1 - 4.4e-06 27.2 0.0 0.00011 22.6 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EMR72433.1 - 2.5e-05 24.6 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMR72433.1 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EMR72433.1 - 0.00063 20.3 0.1 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EMR72433.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EMR72433.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMR72433.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EMR72433.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EMR72433.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EMR72433.1 - 0.0089 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 EMR72433.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EMR72433.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EMR72433.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Prot_ATP_OB_N PF17758.1 EMR72433.1 - 0.023 14.4 0.5 0.086 12.5 0.5 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Sigma54_activat PF00158.26 EMR72433.1 - 0.023 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EMR72433.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EMR72433.1 - 0.03 13.8 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 EMR72433.1 - 0.032 14.0 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMR72433.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMR72433.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HR1 PF02185.16 EMR72433.1 - 0.053 13.7 0.9 0.13 12.4 0.9 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_25 PF13481.6 EMR72433.1 - 0.053 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EMR72433.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EMR72433.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 EMR72433.1 - 0.14 12.4 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Frag1 PF10277.9 EMR72434.1 - 3.3e-15 56.2 1.4 4e-15 55.9 1.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3042 PF11240.8 EMR72434.1 - 0.045 13.8 0.5 0.045 13.8 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) CBFD_NFYB_HMF PF00808.23 EMR72435.1 - 6.2e-05 23.2 0.5 7.5e-05 22.9 0.5 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1980 PF09323.10 EMR72435.1 - 0.026 14.5 0.0 0.028 14.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CENP-W PF15510.6 EMR72435.1 - 0.027 14.7 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein Peptidase_M41 PF01434.18 EMR72436.1 - 7.8e-58 195.5 0.6 1.7e-57 194.4 0.6 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EMR72436.1 - 4.7e-43 146.8 0.0 1.5e-42 145.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMR72436.1 - 4.8e-11 42.3 0.0 1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EMR72436.1 - 5e-06 26.6 0.0 2.4e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMR72436.1 - 2.5e-05 24.7 2.2 0.0012 19.2 2.2 3.5 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EMR72436.1 - 2.6e-05 23.6 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EMR72436.1 - 3.7e-05 24.0 0.2 0.028 14.7 0.1 3.4 2 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EMR72436.1 - 0.00043 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EMR72436.1 - 0.0054 16.5 0.1 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EMR72436.1 - 0.0061 16.7 0.1 0.019 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EMR72436.1 - 0.0074 16.4 0.0 0.024 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EMR72436.1 - 0.012 15.0 0.3 0.038 13.4 0.3 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMR72436.1 - 0.013 15.1 1.0 0.71 9.4 0.2 2.7 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 EMR72436.1 - 0.041 14.4 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMR72436.1 - 0.06 13.6 0.3 0.17 12.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EMR72436.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EMR72436.1 - 0.094 11.9 0.0 0.28 10.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EMR72436.1 - 0.12 11.9 0.0 0.55 9.7 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EMR72436.1 - 0.14 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMR72436.1 - 0.14 11.4 3.4 0.58 9.4 0.5 2.6 1 1 1 2 2 2 0 Zeta toxin AAA_17 PF13207.6 EMR72436.1 - 0.16 12.4 0.3 0.4 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain LSM PF01423.22 EMR72437.1 - 1.2e-19 69.7 0.2 1.4e-19 69.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain UDPGT PF00201.18 EMR72438.1 - 0.0067 15.3 0.0 0.018 13.9 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase LicD PF04991.13 EMR72439.1 - 2.3e-20 73.7 1.0 1.1e-12 48.6 0.6 3.6 3 1 1 4 4 4 3 LicD family WLM PF08325.10 EMR72441.1 - 5.1e-52 176.7 0.0 2.2e-51 174.7 0.0 1.8 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 EMR72441.1 - 0.00097 19.2 0.6 0.0026 17.8 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 ubiquitin PF00240.23 EMR72441.1 - 0.021 14.5 0.2 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin family SprT-like PF10263.9 EMR72441.1 - 0.025 14.4 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Reprolysin_5 PF13688.6 EMR72441.1 - 0.074 13.2 0.4 0.33 11.1 0.4 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12 CsbD PF05532.12 EMR72442.1 - 0.013 15.4 0.5 0.027 14.4 0.5 1.4 1 0 0 1 1 1 0 CsbD-like XRCC4 PF06632.12 EMR72442.1 - 2.7 6.8 9.2 3.1 6.6 9.2 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SRP-alpha_N PF04086.13 EMR72442.1 - 8.2 6.2 16.3 9.5 6.1 16.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Prefoldin_2 PF01920.20 EMR72443.1 - 1.8e-24 85.7 5.3 2.3e-24 85.4 5.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.11 EMR72443.1 - 0.012 16.1 3.1 1.6 9.3 1.0 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4854 PF16146.5 EMR72443.1 - 0.022 15.1 0.8 0.031 14.6 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) FAM167 PF11652.8 EMR72443.1 - 3.8 8.0 7.5 34 5.0 6.8 2.5 1 1 1 2 2 2 0 FAM167 DivIC PF04977.15 EMR72443.1 - 9.5 6.1 9.0 27 4.6 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator Amidase PF01425.21 EMR72444.1 - 5.4e-30 104.7 0.0 1e-29 103.9 0.0 1.3 1 0 0 1 1 1 1 Amidase PRMT5 PF05185.16 EMR72445.1 - 8.9e-67 224.3 0.0 1.2e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EMR72445.1 - 6e-57 192.4 0.0 8.3e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 EMR72445.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PIN_9 PF18477.1 EMR72446.1 - 0.0019 18.5 1.3 0.011 16.0 1.3 2.3 1 0 0 1 1 1 1 PIN like domain Sugar_tr PF00083.24 EMR72447.1 - 3.7e-77 260.1 31.5 4.4e-77 259.9 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR72447.1 - 6.7e-18 64.7 40.3 2.9e-17 62.6 37.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF866 PF05907.13 EMR72448.1 - 6.5e-44 149.6 2.6 2.2e-42 144.6 1.2 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) DUF4379 PF14311.6 EMR72448.1 - 0.035 14.5 0.6 0.075 13.4 0.6 1.6 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Mre11_DNA_bind PF04152.14 EMR72449.1 - 1.7e-48 165.1 1.0 1.7e-48 165.1 1.0 2.7 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EMR72449.1 - 3.6e-10 40.7 1.0 7e-10 39.7 0.4 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMR72449.1 - 0.059 13.6 1.2 0.34 11.1 1.2 2.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain ERAP1_C PF11838.8 EMR72450.1 - 1.1e-81 274.8 0.0 2.5e-80 270.4 0.0 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EMR72450.1 - 8.8e-80 267.3 4.8 1.4e-79 266.7 4.8 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EMR72450.1 - 1.8e-47 162.0 2.3 1.3e-46 159.1 1.2 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EMR72450.1 - 0.021 14.8 0.1 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) DUF45 PF01863.17 EMR72450.1 - 0.065 13.3 0.1 0.32 11.0 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF45 CTP_transf_like PF01467.26 EMR72451.1 - 0.025 14.8 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Cytidylyltransferase-like Tcp11 PF05794.13 EMR72452.1 - 1.3e-97 327.7 0.5 1.3e-97 327.7 0.5 2.5 3 0 0 3 3 3 1 T-complex protein 11 IQ PF00612.27 EMR72452.1 - 0.06 13.2 1.1 0.17 11.7 1.1 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif FAD_binding_4 PF01565.23 EMR72453.1 - 2.8e-22 78.9 0.2 7.9e-22 77.5 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR72453.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like HTH_46 PF15977.5 EMR72454.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding PGAP1 PF07819.13 EMR72455.1 - 0.22 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein F-box-like PF12937.7 EMR72456.1 - 1.1e-06 28.4 0.1 2e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMR72456.1 - 0.00081 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF4449 PF14613.6 EMR72457.1 - 4.8e-69 231.6 2.7 4.8e-69 231.6 2.7 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) DUF1390 PF07150.11 EMR72457.1 - 0.034 13.9 3.2 0.069 12.8 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) DUF5425 PF17472.2 EMR72457.1 - 2.2 9.1 5.3 20 6.1 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5425) YlqD PF11068.8 EMR72457.1 - 2.5 8.5 8.2 0.53 10.7 3.4 2.3 2 0 0 2 2 2 0 YlqD protein DUF1996 PF09362.10 EMR72458.1 - 8.3e-27 94.7 5.3 1.1e-26 94.4 5.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) nos_propeller_2 PF18793.1 EMR72458.1 - 0.095 13.0 0.1 2.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat 2 Aft1_OSA PF11785.8 EMR72458.1 - 2.1 8.8 5.5 11 6.5 0.8 2.3 1 1 1 2 2 2 0 Aft1 osmotic stress response (OSM) domain Viral_Beta_CD PF04530.12 EMR72459.1 - 0.024 14.9 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Viral Beta C/D like family PseudoU_synth_1 PF01416.20 EMR72460.1 - 9.6e-10 38.9 0.0 4e-08 33.7 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase FAD_binding_4 PF01565.23 EMR72461.1 - 6.3e-20 71.3 2.5 1.2e-19 70.4 2.5 1.5 1 0 0 1 1 1 1 FAD binding domain Hormone_3 PF00159.18 EMR72462.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide Asp PF00026.23 EMR72464.1 - 3.2e-24 85.9 0.0 5.2e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 EMR72464.1 - 3.8e-08 32.6 1.0 7.9e-08 31.6 1.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain AcylCoA_DH_N PF12418.8 EMR72464.1 - 0.08 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal DUF1180 PF06679.12 EMR72464.1 - 0.18 12.2 1.9 0.28 11.6 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HET PF06985.11 EMR72465.1 - 8.9e-33 113.7 0.1 1.4e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Med22 PF06179.12 EMR72466.1 - 2.8e-09 37.1 0.8 9.2e-09 35.5 0.0 2.3 2 1 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3391 PF11871.8 EMR72466.1 - 2.4 8.7 12.0 5.3 7.6 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) RR_TM4-6 PF06459.12 EMR72466.1 - 8.1 6.2 16.4 0.36 10.6 4.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 peroxidase PF00141.23 EMR72467.1 - 4.2e-29 101.9 0.3 6.6e-29 101.2 0.3 1.3 1 0 0 1 1 1 1 Peroxidase EMC1_C PF07774.13 EMR72469.1 - 1.2e-63 214.7 0.0 2.1e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EMR72469.1 - 7.6e-25 87.9 9.5 1.1e-19 71.0 3.1 3.7 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 EMR72469.1 - 1.9e-05 24.4 7.6 0.021 14.8 0.1 5.1 6 0 0 6 6 6 3 PQQ enzyme repeat WD40 PF00400.32 EMR72470.1 - 6.5e-37 124.9 28.5 6.5e-08 33.1 0.0 12.3 14 0 0 14 14 13 7 WD domain, G-beta repeat Utp12 PF04003.12 EMR72470.1 - 1.5e-24 86.3 0.0 2.4e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EMR72470.1 - 4.6e-22 78.1 0.0 0.018 15.3 0.0 9.8 3 2 8 11 11 11 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR72470.1 - 5.5e-08 32.1 0.8 1.7 7.5 0.0 6.2 4 3 3 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EMR72470.1 - 5.8e-05 23.1 4.8 0.65 9.8 0.1 4.7 5 1 1 6 6 6 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EMR72470.1 - 0.0012 17.6 4.1 1.9 7.0 0.0 3.9 3 2 1 4 4 4 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EMR72470.1 - 0.0013 17.8 0.0 0.37 9.7 0.0 3.0 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 EMR72470.1 - 0.0019 17.6 0.0 2 7.6 0.0 3.7 3 1 1 4 4 4 1 WD40-like domain Nbas_N PF15492.6 EMR72470.1 - 0.0049 16.2 0.2 12 5.1 0.0 3.9 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal RPN1_RPN2_N PF17781.1 EMR72470.1 - 0.043 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Cytochrom_D1 PF02239.16 EMR72470.1 - 0.075 11.5 0.1 4.3 5.8 0.0 2.9 1 1 1 2 2 2 0 Cytochrome D1 heme domain HMG_box PF00505.19 EMR72471.1 - 1.4e-10 41.4 0.2 2.6e-10 40.6 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MFS_1 PF07690.16 EMR72472.1 - 7.5e-31 107.3 6.5 7.5e-31 107.3 6.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMR72472.1 - 0.00011 21.2 0.6 0.00011 21.2 0.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Ferlin_C PF16165.5 EMR72472.1 - 0.14 12.1 0.3 25 4.8 0.8 2.4 2 0 0 2 2 2 0 Ferlin C-terminus USP7_ICP0_bdg PF12436.8 EMR72473.1 - 2e-86 289.3 0.3 2.8e-84 282.2 0.0 3.1 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EMR72473.1 - 9.7e-76 254.1 2.6 4.4e-71 238.9 0.2 3.5 3 0 0 3 3 3 3 Ubiquitin-specific protease C-terminal UCH PF00443.29 EMR72473.1 - 7.1e-36 124.0 2.3 7.1e-36 124.0 2.3 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMR72473.1 - 2.7e-13 50.2 0.0 4.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EMR72473.1 - 4.4e-10 39.7 0.1 1.1e-09 38.4 0.1 1.7 1 0 0 1 1 1 1 MATH domain adh_short PF00106.25 EMR72474.1 - 2.5e-06 27.1 0.0 4.4e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR72474.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 KR domain Arylsulfotran_2 PF14269.6 EMR72475.1 - 5.4e-49 167.2 1.8 7.7e-49 166.7 1.8 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMR72475.1 - 3.7e-17 62.3 0.4 1.2e-16 60.6 0.4 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Xan_ur_permease PF00860.20 EMR72476.1 - 4.1e-25 88.3 30.8 3.7e-24 85.1 30.8 2.3 1 1 0 1 1 1 1 Permease family BCS1_N PF08740.11 EMR72477.1 - 1.2e-45 155.8 1.8 2.3e-45 154.9 1.8 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EMR72477.1 - 8.5e-20 71.5 0.0 5.6e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMR72477.1 - 0.00046 20.6 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EMR72477.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EMR72477.1 - 0.0069 16.0 0.4 0.037 13.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain ATPase PF06745.13 EMR72477.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 EMR72477.1 - 0.058 13.9 0.0 0.2 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMR72477.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CASP_C PF08172.12 EMR72478.1 - 5.7e-101 337.1 15.3 3.6e-98 327.9 0.0 3.8 4 0 0 4 4 4 2 CASP C terminal bZIP_2 PF07716.15 EMR72478.1 - 0.0042 17.1 3.5 0.0042 17.1 3.5 7.8 7 1 1 8 8 8 1 Basic region leucine zipper ERM PF00769.19 EMR72478.1 - 0.0053 16.6 1.4 0.0053 16.6 1.4 4.1 4 1 0 4 4 4 1 Ezrin/radixin/moesin family DUF4407 PF14362.6 EMR72478.1 - 0.018 14.4 29.4 1.1 8.5 4.1 4.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) SOGA PF11365.8 EMR72478.1 - 0.055 14.6 0.6 0.055 14.6 0.6 6.0 2 1 3 5 5 5 0 Protein SOGA ZapB PF06005.12 EMR72478.1 - 0.057 13.9 0.4 0.057 13.9 0.4 6.5 6 0 0 6 6 6 0 Cell division protein ZapB APG6_N PF17675.1 EMR72478.1 - 0.071 13.6 57.7 0.47 11.0 0.7 5.6 2 1 2 5 5 5 0 Apg6 coiled-coil region FlaC_arch PF05377.11 EMR72478.1 - 0.09 13.2 26.1 3.7 8.0 0.2 6.4 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 EMR72478.1 - 0.17 12.5 0.0 0.17 12.5 0.0 5.8 7 0 0 7 7 5 0 SlyX TPR_MLP1_2 PF07926.12 EMR72478.1 - 0.21 11.6 60.8 0.12 12.5 6.9 7.2 4 1 2 6 6 6 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EMR72478.1 - 0.27 11.4 63.9 0.52 10.5 1.0 5.9 2 1 4 6 6 6 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 EMR72478.1 - 0.38 11.2 43.8 0.35 11.3 17.3 4.1 2 1 2 4 4 4 0 Fez1 Cep57_MT_bd PF06657.13 EMR72478.1 - 0.76 10.3 32.0 0.26 11.8 2.1 5.8 6 1 0 6 6 6 0 Centrosome microtubule-binding domain of Cep57 Shugoshin_N PF07558.11 EMR72478.1 - 0.97 9.4 10.7 1.5 8.7 0.9 4.3 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region GTP-bdg_M PF16360.5 EMR72478.1 - 1.5 9.5 0.0 1.5 9.5 0.0 6.1 3 2 2 5 5 5 0 GTP-binding GTPase Middle Region Tropomyosin_1 PF12718.7 EMR72478.1 - 1.9 8.7 53.5 0.24 11.5 7.8 5.5 3 1 2 5 5 5 0 Tropomyosin like YabA PF06156.13 EMR72478.1 - 3.1 8.5 35.1 2.6 8.7 0.0 6.0 3 2 2 5 5 5 0 Initiation control protein YabA UPF0184 PF03670.13 EMR72478.1 - 5.1 7.6 11.4 2 8.8 0.1 4.3 4 1 1 5 5 4 0 Uncharacterised protein family (UPF0184) Vps39_2 PF10367.9 EMR72479.1 - 2.5e-08 34.3 0.0 5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 p450 PF00067.22 EMR72480.1 - 5.5e-63 213.3 0.0 1.3e-62 212.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 BCDHK_Adom3 PF10436.9 EMR72481.1 - 2.2e-45 154.4 0.0 3.4e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EMR72481.1 - 6.7e-07 29.8 0.0 1.1e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C12 PF01088.21 EMR72482.1 - 4.8e-63 212.7 0.0 6.5e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EMR72482.1 - 2.3e-09 37.0 0.0 2.3e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Septin PF00735.18 EMR72483.1 - 1.3e-114 382.3 0.4 1.8e-114 381.8 0.4 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EMR72483.1 - 2.6e-07 30.7 0.0 6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMR72483.1 - 4.6e-06 26.3 3.8 5.8e-05 22.7 0.2 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMR72483.1 - 1.2e-05 25.3 1.9 5.2e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EMR72483.1 - 0.0023 18.2 0.7 0.0077 16.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EMR72483.1 - 0.0025 17.3 0.1 0.0051 16.3 0.1 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 EMR72483.1 - 0.0038 17.4 0.1 0.0086 16.3 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 EMR72483.1 - 0.01 14.9 0.6 0.017 14.2 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 EMR72483.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.6 EMR72483.1 - 0.017 14.9 0.2 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EMR72483.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 EMR72483.1 - 0.021 14.4 0.7 0.065 12.8 0.4 2.0 2 1 0 2 2 2 0 Ras family FOXP-CC PF16159.5 EMR72483.1 - 0.022 15.4 0.9 0.022 15.4 0.9 2.5 2 1 1 3 3 2 0 FOXP coiled-coil domain AAA_16 PF13191.6 EMR72483.1 - 0.037 14.4 1.6 0.082 13.3 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain Casc1_N PF15927.5 EMR72483.1 - 0.039 13.7 10.8 0.11 12.2 10.8 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus ABC_tran PF00005.27 EMR72483.1 - 0.047 14.2 0.2 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 EMR72483.1 - 0.052 13.5 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 EMR72483.1 - 0.057 12.5 0.3 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 EMR72483.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 EMR72483.1 - 0.12 11.9 0.1 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EMR72483.1 - 0.12 12.1 0.4 4.8 6.9 0.4 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EMR72483.1 - 0.14 12.6 0.0 0.44 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Dynamin_N PF00350.23 EMR72483.1 - 0.74 9.9 7.7 3.6 7.6 0.1 3.2 2 1 1 3 3 3 0 Dynamin family AAA_11 PF13086.6 EMR72483.1 - 2 8.2 6.7 22 4.7 3.5 2.2 2 0 0 2 2 2 0 AAA domain DegS PF05384.11 EMR72483.1 - 9.7 5.7 15.7 15 5.0 12.1 2.8 2 1 0 2 2 2 0 Sensor protein DegS DUF3455 PF11937.8 EMR72484.1 - 4.2e-46 157.2 0.4 6.4e-46 156.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EMR72484.1 - 0.003 17.7 0.4 0.0099 16.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2990) Glyco_hydro_61 PF03443.14 EMR72485.1 - 6.8e-08 32.7 0.0 2.6e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.22 EMR72486.1 - 4.3e-70 236.7 0.0 1e-68 232.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Sel1 PF08238.12 EMR72487.1 - 1.1e-44 149.8 24.4 4.2e-08 33.6 0.2 7.8 7 0 0 7 7 7 7 Sel1 repeat TPR_17 PF13431.6 EMR72487.1 - 0.025 14.9 0.2 7.3 7.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EMR72487.1 - 0.18 12.2 1.0 2.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMR72487.1 - 0.22 12.3 4.6 40 5.1 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MPC PF03650.13 EMR72488.1 - 3.3e-47 159.2 1.0 4.5e-47 158.8 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Abhydrolase_2 PF02230.16 EMR72489.1 - 8e-62 208.9 0.0 9.6e-62 208.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EMR72489.1 - 5.2e-10 39.0 0.1 3e-06 26.7 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EMR72489.1 - 1.5e-06 28.0 0.0 0.00014 21.6 0.0 2.2 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EMR72489.1 - 2.3e-06 27.4 0.2 0.071 12.7 0.6 2.9 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMR72489.1 - 2.5e-06 27.1 0.1 1.9e-05 24.3 0.0 2.2 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 EMR72489.1 - 1.4e-05 24.7 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EMR72489.1 - 0.00014 22.5 0.2 0.0023 18.6 0.5 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EMR72489.1 - 0.00016 21.6 0.0 0.14 12.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2920 PF11144.8 EMR72489.1 - 0.0028 16.9 0.0 0.14 11.3 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) BAAT_C PF08840.11 EMR72489.1 - 0.058 13.3 0.1 0.31 10.9 0.0 2.1 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 EMR72489.1 - 0.18 12.0 0.0 0.43 10.7 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein GFA PF04828.14 EMR72490.1 - 3.6e-22 78.5 0.3 5e-22 78.0 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme LigB PF02900.18 EMR72491.1 - 2.6e-40 138.2 0.0 3e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Glyco_hydro_32N PF00251.20 EMR72492.1 - 1.9e-49 168.9 0.1 3.2e-45 155.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EMR72492.1 - 5.2e-34 117.5 0.4 8.1e-34 116.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal ADH_N PF08240.12 EMR72494.1 - 4.6e-06 26.5 0.0 9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDPD PF03009.17 EMR72496.1 - 1e-18 68.0 0.0 2.5e-18 66.8 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EMR72496.1 - 0.062 13.8 0.1 0.17 12.4 0.1 1.8 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family UvrD_C_2 PF13538.6 EMR72497.1 - 4.8e-06 26.3 0.0 1.4e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 EMR72497.1 - 5.4e-05 22.9 0.0 0.00023 20.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain UvrD_C PF13361.6 EMR72497.1 - 6.9e-05 22.4 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 EMR72497.1 - 0.00031 20.8 0.3 0.00046 20.2 0.3 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 EMR72497.1 - 0.033 14.3 0.2 0.062 13.4 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF83 RRM_1 PF00076.22 EMR72498.1 - 3.3e-21 74.9 0.6 4.7e-10 39.2 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 EMR72498.1 - 3.7e-21 75.5 0.9 5.6e-20 71.6 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72498.1 - 1.2e-12 47.9 0.1 2.2e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72498.1 - 4.9e-08 33.1 0.3 7.8e-08 32.4 0.3 1.3 1 0 0 1 1 1 1 KR domain RRM_7 PF16367.5 EMR72498.1 - 0.00083 19.4 0.1 0.23 11.6 0.1 2.8 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EMR72498.1 - 0.025 14.6 0.0 0.46 10.5 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GDP_Man_Dehyd PF16363.5 EMR72498.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMR72498.1 - 0.076 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_2 PF00891.18 EMR72499.1 - 7.9e-19 67.8 0.0 1.2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 EMR72499.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase CENP-F_leu_zip PF10473.9 EMR72500.1 - 7.9e-06 25.9 15.8 0.00015 21.8 2.3 4.9 1 1 4 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EMR72500.1 - 0.013 16.0 63.2 0.11 13.1 10.9 4.8 1 1 4 5 5 5 0 Apg6 coiled-coil region DUF1664 PF07889.12 EMR72500.1 - 0.33 11.0 19.5 8.4 6.5 0.2 4.9 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) PspB PF06667.12 EMR72500.1 - 0.37 10.9 2.7 3.7 7.7 0.1 3.7 2 0 0 2 2 2 0 Phage shock protein B RICH PF05062.12 EMR72500.1 - 0.52 10.7 6.8 0.55 10.6 4.6 2.3 1 1 1 2 2 2 0 RICH domain ETX_MTX2 PF03318.13 EMR72501.1 - 0.16 11.7 4.8 0.23 11.2 4.8 1.1 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF1727 PF08353.10 EMR72501.1 - 0.3 11.0 1.3 0.7 9.9 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Spt20 PF12090.8 EMR72501.1 - 0.4 10.3 10.1 0.69 9.5 10.1 1.3 1 0 0 1 1 1 0 Spt20 family XAP5 PF04921.14 EMR72501.1 - 0.48 10.2 3.5 0.9 9.3 3.5 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator RPEL PF02755.15 EMR72502.1 - 1.3e-17 62.9 5.4 2.6e-09 36.5 0.6 2.6 2 0 0 2 2 2 2 RPEL repeat tRNA-synt_1 PF00133.22 EMR72503.1 - 3.1e-159 531.0 0.0 4.1e-159 530.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EMR72503.1 - 3.6e-22 78.7 0.0 1.1e-13 50.8 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EMR72503.1 - 1.8e-15 57.2 0.0 3.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EMR72503.1 - 0.00049 19.5 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 EMR72503.1 - 0.0017 18.2 2.9 0.0046 16.8 2.9 1.8 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 EMR72503.1 - 0.0047 16.5 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 FKBP_C PF00254.28 EMR72504.1 - 6.7e-18 64.8 0.4 5.8e-10 39.4 0.1 2.4 1 1 1 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Amino_oxidase PF01593.24 EMR72505.1 - 7.7e-26 91.4 0.0 8.9e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase MFS_1 PF07690.16 EMR72506.1 - 3.4e-33 115.0 31.3 4.5e-33 114.6 31.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 EMR72507.1 - 8.7e-17 61.4 0.4 1.3e-16 60.9 0.4 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMR72507.1 - 5.7e-12 45.7 0.1 9.5e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMR72507.1 - 9.8e-12 45.1 0.2 3e-11 43.6 0.4 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMR72507.1 - 0.00018 22.2 0.0 0.00025 21.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMR72507.1 - 0.00027 21.1 0.0 0.00046 20.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMR72507.1 - 0.0035 17.4 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMR72507.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF1771 PF08590.10 EMR72507.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) FAD_binding_3 PF01494.19 EMR72508.1 - 9.2e-16 58.0 0.2 5.8e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EMR72508.1 - 1.9e-05 24.1 0.1 4.5e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR72508.1 - 6.3e-05 23.1 0.3 0.00019 21.6 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMR72508.1 - 0.00037 20.2 2.8 0.00038 20.2 1.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR72508.1 - 0.00039 19.6 0.9 0.00039 19.6 0.9 2.1 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EMR72508.1 - 0.00055 19.2 0.1 0.00095 18.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 EMR72508.1 - 0.0006 19.2 0.5 1.2 8.3 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EMR72508.1 - 0.0012 18.8 1.6 0.015 15.3 1.3 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EMR72508.1 - 0.0019 17.3 1.9 0.024 13.7 0.1 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EMR72508.1 - 0.0026 17.1 1.1 0.045 13.0 0.3 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMR72508.1 - 0.025 13.3 0.6 0.037 12.7 0.6 1.5 1 1 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EMR72508.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EMR72508.1 - 0.18 10.9 0.2 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Erythro_esteras PF05139.14 EMR72509.1 - 3.2e-95 319.9 0.9 3.2e-95 319.9 0.9 1.7 1 1 1 2 2 2 1 Erythromycin esterase DUF3738 PF12543.8 EMR72509.1 - 0.009 16.2 0.0 0.2 11.8 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3738) IMS PF00817.20 EMR72510.1 - 3.1e-42 144.1 0.1 9.6e-42 142.5 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EMR72510.1 - 2.8e-13 50.6 0.2 1.3e-12 48.5 0.2 2.2 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EMR72510.1 - 0.0016 18.6 0.0 0.0045 17.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif RE_MjaI PF09568.10 EMR72510.1 - 0.12 12.2 2.3 0.33 10.8 2.3 1.7 1 0 0 1 1 1 0 MjaI restriction endonuclease Kinesin PF00225.23 EMR72511.1 - 4.8e-109 364.3 0.6 4.8e-109 364.3 0.6 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EMR72511.1 - 4.9e-23 81.7 0.0 4.9e-23 81.7 0.0 3.2 3 1 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 EMR72511.1 - 4.7e-06 27.0 0.1 4.7e-06 27.0 0.1 6.4 5 1 0 5 5 5 2 Kinesin-associated microtubule-binding YL1 PF05764.13 EMR72512.1 - 0.33 11.1 9.3 0.13 12.3 3.6 2.2 2 0 0 2 2 2 0 YL1 nuclear protein SPT6_acidic PF14632.6 EMR72512.1 - 1.2 9.8 22.6 17 6.0 0.6 3.3 2 1 1 3 3 3 0 Acidic N-terminal SPT6 MFS_1 PF07690.16 EMR72513.1 - 8.4e-35 120.3 23.0 8.4e-35 120.3 23.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily PI3Ka PF00613.20 EMR72513.1 - 0.21 11.0 0.1 0.46 9.9 0.0 1.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Fungal_trans_2 PF11951.8 EMR72514.1 - 4.2e-12 45.6 0.0 5.5e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Soc PF16855.5 EMR72514.1 - 0.2 12.2 0.0 14 6.2 0.0 2.3 2 0 0 2 2 2 0 Small outer capsid protein adh_short PF00106.25 EMR72516.1 - 4.4e-36 124.2 0.0 5.9e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72516.1 - 4.6e-30 104.9 0.0 6.2e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72516.1 - 1.2e-07 31.9 3.1 8e-07 29.1 3.1 2.0 1 1 0 1 1 1 1 KR domain BioW PF03744.13 EMR72516.1 - 0.19 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase Pkinase PF00069.25 EMR72517.1 - 4.9e-13 49.0 0.0 1.3e-06 28.0 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR72517.1 - 0.02 14.2 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase NACHT_N PF17100.5 EMR72518.1 - 6.1e-05 23.0 0.1 6.1e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 EMR72518.1 - 0.00013 21.9 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMR72518.1 - 0.00041 20.8 0.0 0.0016 18.8 0.0 2.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EMR72518.1 - 0.0054 17.0 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMR72518.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EMR72518.1 - 0.063 12.5 0.4 1.1 8.5 0.0 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) STIMATE PF12400.8 EMR72519.1 - 1.6e-40 138.5 5.4 1.6e-40 138.5 5.4 1.7 2 0 0 2 2 2 1 STIMATE family TMEM154 PF15102.6 EMR72519.1 - 0.059 13.3 0.0 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family SF3b1 PF08920.10 EMR72520.1 - 9.5e-19 68.0 0.9 9.5e-19 68.0 0.9 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EMR72520.1 - 2.8e-12 46.9 6.6 0.54 10.7 0.0 8.2 7 1 3 10 10 10 3 HEAT repeats HEAT_EZ PF13513.6 EMR72520.1 - 2.7e-11 43.7 3.8 0.011 16.2 0.0 7.4 8 2 2 10 10 8 2 HEAT-like repeat HEAT PF02985.22 EMR72520.1 - 8.5e-10 38.1 9.7 0.089 13.1 0.1 9.5 11 0 0 11 11 10 1 HEAT repeat Cnd1 PF12717.7 EMR72520.1 - 5.1e-06 26.6 2.8 0.78 9.8 0.0 6.4 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EMR72520.1 - 7.3e-05 23.3 1.2 1.9 9.1 0.0 5.3 5 1 1 6 6 5 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 EMR72520.1 - 0.00011 21.5 0.5 4.7 6.2 0.0 4.9 4 1 1 6 6 6 1 Dopey, N-terminal MMS19_C PF12460.8 EMR72520.1 - 0.00016 21.0 0.0 0.012 14.8 0.0 3.2 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal NUC173 PF08161.12 EMR72520.1 - 0.0005 19.8 0.5 1.2 8.8 0.0 4.0 5 0 0 5 5 5 2 NUC173 domain DUF3385 PF11865.8 EMR72520.1 - 0.0014 18.6 2.7 0.037 13.9 0.1 4.4 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 EMR72520.1 - 0.0032 17.1 0.1 0.93 9.0 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal UNC45-central PF11701.8 EMR72520.1 - 0.0033 17.4 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 1 1 Myosin-binding striated muscle assembly central DUF1428 PF07237.11 EMR72520.1 - 0.11 12.8 0.0 3.6 7.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) DRIM PF07539.12 EMR72520.1 - 0.13 10.6 0.1 9.6 4.4 0.0 3.3 2 1 1 3 3 3 0 Down-regulated in metastasis DUF4764 PF15961.5 EMR72520.1 - 2.6 6.6 7.5 3.4 6.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4764) RRM_1 PF00076.22 EMR72522.1 - 3.8e-13 49.1 0.2 5.7e-13 48.5 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMR72522.1 - 0.013 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 EMR72522.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated PTH2 PF01981.16 EMR72523.1 - 0.046 14.0 0.3 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 MKT1_C PF12246.8 EMR72525.1 - 2.6e-69 233.1 0.0 3.8e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EMR72525.1 - 2.1e-27 95.3 0.1 4.6e-27 94.2 0.1 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EMR72525.1 - 0.0028 18.1 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain AMP-binding PF00501.28 EMR72526.1 - 1.7e-17 63.1 0.0 3.9e-17 62.0 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme SNRNP27 PF08648.12 EMR72527.1 - 1.3e-28 98.9 0.4 2.2e-28 98.1 0.4 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF3682 PF12446.8 EMR72527.1 - 0.85 10.1 6.8 1.7 9.1 6.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) Elong_Iki1 PF10483.9 EMR72528.1 - 7.5e-97 324.4 0.0 8.7e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 AA_permease PF00324.21 EMR72529.1 - 8.8e-47 159.8 26.8 1.1e-46 159.5 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR72529.1 - 1.1e-12 47.5 29.6 1.6e-12 47.0 29.6 1.2 1 0 0 1 1 1 1 Amino acid permease 2OG-FeII_Oxy PF03171.20 EMR72530.1 - 1.4e-12 48.0 0.0 2.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EMR72531.1 - 7.8e-43 146.7 55.1 1.8e-42 145.6 51.3 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMR72531.1 - 7.4e-15 54.4 21.3 1.2e-14 53.7 21.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMR72531.1 - 2.4e-10 39.9 8.7 2.4e-10 39.9 8.7 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter DUF4129 PF13559.6 EMR72531.1 - 0.24 11.7 1.8 0.54 10.6 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) OATP PF03137.20 EMR72531.1 - 0.29 9.4 22.9 0.71 8.1 18.5 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF423 PF04241.15 EMR72531.1 - 0.82 9.9 11.8 0.11 12.7 0.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) Dicty_REP PF05086.12 EMR72534.1 - 3.1 5.7 4.4 4.5 5.1 4.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ASXH PF13919.6 EMR72535.1 - 1.5e-32 112.5 0.2 2.9e-32 111.6 0.2 1.5 1 0 0 1 1 1 1 Asx homology domain SLC12 PF03522.15 EMR72536.1 - 1e-08 34.7 0.1 1.3e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Solute carrier family 12 DUF2264 PF10022.9 EMR72538.1 - 3e-80 270.0 2.8 8.9e-65 219.1 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2264) LysM PF01476.20 EMR72538.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 LysM domain PAS_10 PF13596.6 EMR72539.1 - 0.0099 16.5 0.1 0.017 15.7 0.1 1.3 1 0 0 1 1 1 1 PAS domain DNA_pol_E_B PF04042.16 EMR72540.1 - 1.7e-39 135.4 0.2 1.2e-31 109.7 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EMR72540.1 - 2e-38 131.4 0.0 3.2e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Elong-fact-P_C PF09285.11 EMR72540.1 - 0.11 12.3 0.1 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor P, C-terminal DUF4334 PF14232.6 EMR72540.1 - 0.14 12.2 0.2 0.35 10.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) Glyco_hydro_63 PF03200.16 EMR72541.1 - 8.3e-168 559.1 0.1 1.4e-166 555.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EMR72541.1 - 2.8e-83 279.5 0.0 1.1e-82 277.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EMR72541.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Trehalase Zn_clus PF00172.18 EMR72542.1 - 1.3e-07 31.7 11.8 1.8e-07 31.2 11.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR72542.1 - 0.00018 20.6 1.4 0.00031 19.8 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MTS PF05175.14 EMR72543.1 - 1.2e-05 25.0 0.0 0.018 14.6 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain N6_Mtase PF02384.16 EMR72543.1 - 0.00046 19.6 0.0 0.81 8.9 0.0 2.1 2 0 0 2 2 2 2 N-6 DNA Methylase Methyltransf_31 PF13847.6 EMR72543.1 - 0.00084 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 EMR72543.1 - 0.005 16.3 0.0 0.008 15.7 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_32 PF13679.6 EMR72543.1 - 0.0051 16.8 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR72543.1 - 0.0086 16.8 0.0 0.022 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 EMR72543.1 - 0.015 15.8 0.3 0.7 10.5 0.1 2.5 2 0 0 2 2 2 0 PrmC N-terminal domain Methyltransf_23 PF13489.6 EMR72543.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EMR72543.1 - 0.02 14.3 0.0 0.062 12.7 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Rhomboid_SP PF12595.8 EMR72543.1 - 0.074 12.4 4.8 0.14 11.5 4.8 1.4 1 0 0 1 1 1 0 Rhomboid serine protease AMP-binding PF00501.28 EMR72544.1 - 5.2e-38 130.7 0.0 7.8e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EMR72544.1 - 1.7e-05 24.6 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PH PF00169.29 EMR72545.1 - 4e-05 24.1 0.4 0.00021 21.7 0.1 2.4 2 0 0 2 2 2 1 PH domain polyprenyl_synt PF00348.17 EMR72546.1 - 7.8e-93 310.2 0.0 9.2e-93 310.0 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Homeodomain PF00046.29 EMR72546.1 - 0.12 12.3 0.3 0.46 10.4 0.1 2.1 2 0 0 2 2 2 0 Homeodomain Sugar_tr PF00083.24 EMR72547.1 - 1.5e-81 274.6 13.5 6.3e-65 219.8 5.8 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMR72547.1 - 7.3e-14 51.5 3.2 7.3e-14 51.5 3.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily UPF0029 PF01205.19 EMR72548.1 - 4.5e-33 113.7 0.0 6.9e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EMR72548.1 - 3.3e-08 33.8 0.0 6.6e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 RWD domain AA_permease_2 PF13520.6 EMR72549.1 - 1.4e-60 205.4 37.9 1.8e-60 205.0 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMR72549.1 - 8.1e-28 97.2 24.7 8.1e-28 97.2 24.7 1.6 2 0 0 2 2 2 1 Amino acid permease CoatB PF10389.9 EMR72549.1 - 1.2 9.1 11.2 0.36 10.7 0.9 3.3 3 0 0 3 3 3 0 Bacteriophage coat protein B TRAPPC9-Trs120 PF08626.11 EMR72550.1 - 1.5e-242 807.7 0.0 2.5e-242 806.9 0.0 1.3 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ASH PF15780.5 EMR72550.1 - 0.0025 18.0 1.5 0.0076 16.4 0.0 2.5 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin NOP19 PF10863.8 EMR72550.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Nucleolar protein 19 FSA_C PF10479.9 EMR72550.1 - 2.8 6.0 4.9 4.3 5.3 4.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus tRNA-synt_1 PF00133.22 EMR72551.1 - 3.2e-34 118.2 5.2 4e-22 78.2 3.9 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EMR72551.1 - 2.1e-27 95.9 0.0 6.1e-22 77.9 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EMR72551.1 - 3e-12 46.4 0.0 6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Anticodon_1 PF08264.13 EMR72551.1 - 9.6e-12 45.1 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA p450 PF00067.22 EMR72552.1 - 9.2e-42 143.3 0.0 1.2e-40 139.6 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 Dynamin_M PF01031.20 EMR72553.1 - 4.5e-100 334.5 0.0 8.5e-100 333.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EMR72553.1 - 1.4e-57 194.4 0.0 2.4e-57 193.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EMR72553.1 - 8.7e-30 102.7 6.6 9.2e-30 102.7 3.9 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EMR72553.1 - 3.4e-06 27.1 0.3 6.8e-05 22.9 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.9 EMR72553.1 - 0.018 14.4 0.1 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) FeoB_N PF02421.18 EMR72553.1 - 0.059 12.9 0.2 18 4.8 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_15 PF13175.6 EMR72553.1 - 0.077 12.7 0.2 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain adh_short PF00106.25 EMR72554.1 - 3.5e-23 82.1 0.0 6.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72554.1 - 9.4e-20 71.2 0.0 1.6e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72554.1 - 7.5e-05 22.7 0.0 0.0002 21.3 0.0 1.6 1 1 0 1 1 1 1 KR domain Spt20 PF12090.8 EMR72554.1 - 0.00086 19.0 2.6 0.0012 18.5 2.6 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 EMR72554.1 - 0.004 17.2 2.9 0.0055 16.8 2.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 EMR72554.1 - 0.095 11.4 1.2 0.14 10.8 1.2 1.2 1 0 0 1 1 1 0 Hamartin protein DUF1776 PF08643.10 EMR72554.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) E_Pc_C PF06752.12 EMR72554.1 - 5.9 6.9 8.6 10 6.1 8.6 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus RNA_pol_L_2 PF13656.6 EMR72555.1 - 2.2e-21 75.4 0.0 2.7e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EMR72555.1 - 3.3e-05 23.2 0.0 6.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NIR_SIR PF01077.22 EMR72555.1 - 0.088 12.3 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Glyco_hydro_61 PF03443.14 EMR72556.1 - 7.8e-27 94.6 0.0 9.6e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Vps55 PF04133.14 EMR72557.1 - 4.4e-45 152.4 6.3 5e-45 152.2 6.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 CLPTM1 PF05602.12 EMR72558.1 - 4.7e-150 500.3 0.0 5.8e-150 500.1 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) 2TM PF13239.6 EMR72558.1 - 2.2 8.6 5.8 2.3 8.6 1.4 2.9 2 0 0 2 2 2 0 2TM domain Chorismate_bind PF00425.18 EMR72559.1 - 1.4e-58 198.5 0.0 4.4e-57 193.6 0.0 2.8 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EMR72559.1 - 1.3e-22 80.5 0.1 3.9e-14 52.9 0.0 3.1 3 0 0 3 3 3 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EMR72559.1 - 2.5e-13 50.4 0.0 6.4e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EMR72559.1 - 9e-06 25.6 0.0 3.6e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 Pro_dh-DNA_bdg PF14850.6 EMR72559.1 - 0.041 14.4 0.1 0.16 12.5 0.0 2.0 2 0 0 2 2 2 0 DNA-binding domain of Proline dehydrogenase WD40 PF00400.32 EMR72560.1 - 9.8e-21 73.7 11.2 1.6e-07 31.9 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 EMR72560.1 - 3.2e-16 59.6 0.3 5.4e-16 58.9 0.3 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EMR72560.1 - 0.00055 18.7 3.6 0.071 11.8 0.1 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Aa_trans PF01490.18 EMR72561.1 - 1.3e-77 261.2 25.7 1.7e-77 260.9 25.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Clr5 PF14420.6 EMR72563.1 - 3.9e-15 55.8 0.8 3.9e-15 55.8 0.8 2.3 3 0 0 3 3 3 1 Clr5 domain KNTase_C PF07827.11 EMR72563.1 - 0.12 12.1 0.1 0.84 9.5 0.0 2.2 2 0 0 2 2 2 0 KNTase C-terminal domain TetR_C_16 PF17920.1 EMR72563.1 - 0.14 12.4 1.4 0.47 10.7 1.4 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CCDC24 PF15669.5 EMR72563.1 - 0.3 10.9 3.7 4 7.3 3.7 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family NmrA PF05368.13 EMR72564.1 - 2e-81 273.0 0.0 2.5e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMR72564.1 - 2.4e-06 27.5 0.1 1.1e-05 25.4 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding DUF3798 PF12683.7 EMR72564.1 - 0.013 14.9 0.0 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3798) Spt4 PF06093.13 EMR72565.1 - 9e-32 109.0 0.6 1.2e-31 108.7 0.6 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Auto_anti-p27 PF06677.12 EMR72565.1 - 0.19 11.9 2.2 0.29 11.3 2.2 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) LSM PF01423.22 EMR72567.1 - 2.7e-22 78.2 0.1 3.1e-22 78.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMR72567.1 - 0.03 14.4 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain RmlD_sub_bind PF04321.17 EMR72568.1 - 1.1e-49 169.1 0.0 7.4e-49 166.4 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EMR72568.1 - 7.6e-20 71.4 0.0 9.3e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMR72568.1 - 6.8e-10 38.8 0.0 4.7e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMR72568.1 - 3.3e-08 33.0 0.3 4.1e-06 26.1 0.3 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EMR72568.1 - 9.3e-08 31.5 0.0 6e-05 22.3 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EMR72568.1 - 4.6e-07 29.1 0.0 1.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EMR72568.1 - 0.0092 15.6 0.2 0.15 11.6 0.1 2.5 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EMR72568.1 - 0.076 12.5 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Longin PF13774.6 EMR72569.1 - 7e-23 80.5 0.0 1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EMR72569.1 - 1.7e-16 59.7 0.1 2.8e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF5435 PF17503.2 EMR72569.1 - 0.029 14.1 0.1 0.052 13.3 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5435) DUF4404 PF14357.6 EMR72569.1 - 0.075 13.7 0.3 4.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Lysine_decarbox PF03641.14 EMR72570.1 - 1.1e-27 96.7 0.0 1.5e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EMR72570.1 - 4.6e-07 29.5 4.2 2e-06 27.5 4.2 1.9 1 1 0 1 1 1 1 SLOG cluster4 family Proteasome PF00227.26 EMR72571.1 - 2.9e-48 163.9 0.1 3.8e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMR72571.1 - 2e-11 43.3 0.2 3.8e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PPP5 PF08321.12 EMR72572.1 - 6.2e-32 109.8 2.7 9.1e-32 109.2 0.8 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 EMR72572.1 - 1.1e-31 111.0 0.0 1.6e-31 110.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EMR72572.1 - 4.3e-18 64.3 4.3 2.1e-06 27.3 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMR72572.1 - 3e-14 51.9 2.7 6e-05 22.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMR72572.1 - 1.1e-09 37.8 5.9 0.0025 17.4 0.0 3.9 3 1 1 4 4 4 3 TPR repeat TPR_17 PF13431.6 EMR72572.1 - 5.3e-09 35.8 2.7 0.0049 17.2 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMR72572.1 - 9.7e-06 26.0 0.1 0.044 14.3 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMR72572.1 - 3.9e-05 23.5 3.3 0.095 13.0 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR72572.1 - 6.1e-05 23.6 0.4 1.2 9.8 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMR72572.1 - 0.00015 21.8 0.0 0.23 11.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMR72572.1 - 0.00019 22.0 1.1 0.43 11.5 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMR72572.1 - 0.012 16.1 1.1 1.2 9.9 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMR72572.1 - 0.016 15.5 0.1 3.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PIN_5 PF08745.11 EMR72572.1 - 0.044 13.2 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 PINc domain ribonuclease 4HBT_3 PF13622.6 EMR72573.1 - 9.5e-35 121.0 5.3 2.2e-18 67.4 0.5 2.1 1 1 1 2 2 2 2 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMR72573.1 - 1.9e-05 24.5 0.0 0.00097 19.0 0.0 2.8 3 0 0 3 3 3 1 Acyl-CoA thioesterase DNA_pol_A_exo1 PF01612.20 EMR72574.1 - 2.1e-05 24.3 0.0 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease CoA_transf_3 PF02515.17 EMR72575.1 - 2.4e-68 231.0 0.0 3.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III SR-25 PF10500.9 EMR72575.1 - 9.8 5.7 8.1 15 5.1 8.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein adh_short PF00106.25 EMR72577.1 - 4.4e-18 65.4 0.1 5.2e-16 58.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72577.1 - 7.2e-12 45.4 0.0 2.6e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72577.1 - 7.4e-08 32.5 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Aminotran_5 PF00266.19 EMR72578.1 - 3.4e-34 118.4 0.0 1.1e-21 77.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V AAA_14 PF13173.6 EMR72578.1 - 0.098 12.7 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain ANAPC8 PF04049.13 EMR72579.1 - 6.7e-57 191.5 0.8 1.2e-56 190.6 0.2 1.8 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EMR72579.1 - 3.7e-19 67.7 1.9 0.00068 19.4 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMR72579.1 - 7.5e-19 66.3 7.8 7.2e-05 22.7 0.0 6.3 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EMR72579.1 - 3.8e-10 39.1 16.5 0.34 11.1 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMR72579.1 - 5.2e-10 39.3 12.0 0.006 17.3 0.1 6.7 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMR72579.1 - 8.1e-08 31.8 0.1 2.5e-06 27.1 0.1 2.9 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EMR72579.1 - 2.5e-07 31.2 14.8 7.9e-06 26.4 1.1 5.4 4 2 1 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMR72579.1 - 6.4e-06 26.3 8.0 0.053 13.7 0.4 5.5 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EMR72579.1 - 3e-05 23.8 9.0 0.53 10.4 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMR72579.1 - 0.00014 22.1 18.7 0.51 10.7 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat DUF3856 PF12968.7 EMR72579.1 - 0.00058 20.0 2.4 0.011 15.8 0.2 3.0 2 1 1 3 3 2 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 EMR72579.1 - 0.00074 20.0 10.4 6.2 7.4 0.0 6.6 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EMR72579.1 - 0.0068 16.5 11.8 0.2 11.8 0.2 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMR72579.1 - 0.028 14.3 0.4 33 4.5 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4164 PF13747.6 EMR72579.1 - 0.069 13.4 0.3 0.19 12.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ChAPs PF09295.10 EMR72579.1 - 0.087 11.8 0.0 3 6.7 0.0 2.1 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 EMR72579.1 - 0.1 13.1 0.3 9.8 6.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 EMR72579.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Sel1 PF08238.12 EMR72579.1 - 0.16 12.7 8.4 9.2 7.1 0.2 4.6 4 0 0 4 4 4 0 Sel1 repeat TPR_6 PF13174.6 EMR72579.1 - 0.53 11.0 16.5 2.1 9.1 0.0 7.2 8 1 1 9 9 6 0 Tetratricopeptide repeat Arm_3 PF16186.5 EMR72580.1 - 0.063 12.8 0.8 0.15 11.6 0.8 1.6 1 0 0 1 1 1 0 Atypical Arm repeat NMT1 PF09084.11 EMR72581.1 - 2.7e-14 53.7 0.0 4.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EMR72581.1 - 7.9e-06 25.5 0.0 1.6e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 EMR72581.1 - 8.7e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 EMR72581.1 - 0.00069 19.3 0.0 0.0009 18.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein RabGAP-TBC PF00566.18 EMR72582.1 - 1.4e-34 119.6 2.8 6.5e-34 117.5 2.8 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EMR72582.1 - 1.1e-07 31.5 0.0 0.00013 21.5 0.1 3.3 2 1 0 2 2 2 2 Rab-binding domain (RBD) MFS_2 PF13347.6 EMR72583.1 - 0.085 11.4 0.4 0.12 10.9 0.4 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein SpoIIIAH PF12685.7 EMR72583.1 - 0.27 11.0 21.1 3.4 7.5 0.0 2.7 2 1 0 2 2 2 0 SpoIIIAH-like protein AAA_11 PF13086.6 EMR72583.1 - 2.6 7.8 14.2 13 5.4 9.9 2.2 2 0 0 2 2 2 0 AAA domain DUF3450 PF11932.8 EMR72583.1 - 7.8 5.7 14.3 13 5.0 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NUDIX PF00293.28 EMR72584.1 - 1.3e-16 60.8 1.2 1.6e-16 60.5 1.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 EMR72584.1 - 0.095 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Fascin PF06268.13 EMR72585.1 - 0.0049 17.1 0.0 0.017 15.4 0.0 1.9 1 1 1 2 2 2 1 Fascin domain GFO_IDH_MocA PF01408.22 EMR72587.1 - 1.1e-17 65.0 0.0 2.1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMR72587.1 - 1.2e-17 64.0 0.4 7.9e-17 61.3 0.1 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EMR72587.1 - 0.0057 17.3 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Noggin PF05806.12 EMR72588.1 - 0.1 12.5 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Noggin WSC PF01822.19 EMR72589.1 - 5e-15 55.5 5.7 9.1e-15 54.6 5.7 1.5 1 0 0 1 1 1 1 WSC domain Abhydrolase_6 PF12697.7 EMR72589.1 - 0.0026 18.4 2.3 0.0026 18.4 2.3 2.9 1 1 2 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR72589.1 - 0.029 13.6 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EMR72589.1 - 0.039 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EMR72589.1 - 0.052 13.3 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein adh_short PF00106.25 EMR72590.1 - 1.5e-27 96.3 0.1 1.9e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72590.1 - 3.6e-22 79.1 0.1 4.3e-22 78.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EMR72590.1 - 4.5e-07 29.9 0.1 5.3e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMR72590.1 - 5.4e-06 26.4 0.1 7.2e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMR72590.1 - 0.0024 17.3 0.0 0.098 12.0 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EMR72590.1 - 0.012 15.1 0.2 0.016 14.8 0.2 1.1 1 0 0 1 1 1 0 NmrA-like family DFP PF04127.15 EMR72590.1 - 0.017 14.9 0.2 0.026 14.3 0.2 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 EMR72590.1 - 0.023 14.2 0.0 0.027 14.0 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMR72590.1 - 0.025 13.7 0.1 0.031 13.4 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Aa_trans PF01490.18 EMR72591.1 - 7e-86 288.5 9.2 7e-86 288.5 9.2 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.6 EMR72591.1 - 0.007 16.4 3.2 0.007 16.4 3.2 3.3 4 0 0 4 4 4 1 Alpha/beta-hydrolase family N-terminus WD40 PF00400.32 EMR72592.1 - 7.7e-19 67.7 5.3 0.0032 18.3 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR72592.1 - 4.5e-08 33.3 0.0 0.059 13.7 0.0 4.1 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMR72592.1 - 0.00077 18.5 0.1 0.35 9.8 0.0 3.9 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cucumopine_C PF18631.1 EMR72593.1 - 5.1e-14 52.4 0.0 7.4e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Cucumopine synthase C-terminal helical bundle domain DUF3830 PF12903.7 EMR72593.1 - 0.00057 19.6 0.0 0.00094 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) Aconitase PF00330.20 EMR72594.1 - 1.6e-148 495.6 0.0 1.9e-148 495.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMR72594.1 - 4.5e-34 117.6 0.0 7.5e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain BATS PF06968.13 EMR72595.1 - 1.4e-23 82.8 0.0 5.2e-23 81.0 0.0 2.0 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EMR72595.1 - 1.3e-13 51.6 0.1 2.3e-12 47.6 0.1 2.1 2 0 0 2 2 2 1 Radical SAM superfamily MFS_1 PF07690.16 EMR72596.1 - 8.9e-33 113.7 23.1 8.9e-33 113.7 23.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR72596.1 - 6.1e-06 25.3 1.6 1.2e-05 24.4 0.8 2.0 1 1 0 1 1 1 1 MFS_1 like family Aminotran_3 PF00202.21 EMR72597.1 - 5.4e-35 120.8 0.0 1.6e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EMR72597.1 - 4.2e-11 43.0 0.0 8.9e-05 22.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain Hydantoinase_B PF02538.14 EMR72598.1 - 1.4e-185 617.6 2.0 2.5e-185 616.8 2.0 1.4 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMR72598.1 - 1.5e-82 277.1 0.4 7.8e-82 274.8 0.0 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMR72598.1 - 3.4e-55 186.5 2.2 1.2e-53 181.4 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 EMR72598.1 - 0.099 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature SNF2_N PF00176.23 EMR72599.1 - 8.2e-26 90.5 0.1 1.8e-25 89.4 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EMR72599.1 - 3.1e-08 33.8 0.0 8.7e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMR72599.1 - 0.00062 20.1 0.1 0.0018 18.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMR72599.1 - 0.047 13.5 0.3 0.94 9.2 0.3 2.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EMR72599.1 - 0.17 12.1 0.1 14 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain NMN_transporter PF04973.12 EMR72600.1 - 0.033 14.2 1.0 0.041 13.9 1.0 1.1 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter MFS_1 PF07690.16 EMR72601.1 - 1.5e-26 93.2 80.7 1.3e-20 73.7 46.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMR72601.1 - 0.0039 16.1 2.3 0.0039 16.1 2.3 3.2 2 1 0 2 2 2 1 MFS_1 like family His_Phos_2 PF00328.22 EMR72602.1 - 1.8e-23 83.5 0.0 2.5e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GNAT_acetyltran PF12746.7 EMR72602.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase eRF1_1 PF03463.15 EMR72603.1 - 3.1e-41 140.4 0.0 5.8e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EMR72603.1 - 5.6e-21 75.2 0.0 9.4e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EMR72603.1 - 1.2e-18 67.6 0.0 2.4e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.21 EMR72604.1 - 1e-33 116.8 0.0 1.1e-23 83.9 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family WD40 PF00400.32 EMR72605.1 - 1.2e-06 29.1 0.0 0.00045 21.0 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat NAD_binding_10 PF13460.6 EMR72606.1 - 1.7e-14 54.1 0.0 8.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 NAD(P)H-binding Glyco_hydro_16 PF00722.21 EMR72607.1 - 9.6e-45 152.2 6.5 1.7e-44 151.4 6.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EMR72607.1 - 0.042 14.3 12.8 0.1 13.1 12.8 1.7 1 0 0 1 1 1 0 Chitin recognition protein Lactonase PF10282.9 EMR72608.1 - 2.6e-54 184.8 0.4 3.4e-54 184.4 0.4 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Myb_DNA-binding PF00249.31 EMR72609.1 - 0.0043 17.2 0.5 0.019 15.2 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMR72610.1 - 2.9e-16 59.4 1.4 2.1e-09 37.4 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMR72610.1 - 2e-10 40.8 0.5 0.00031 20.9 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain MMR1 PF08505.10 EMR72610.1 - 7 6.9 13.8 15 5.8 13.8 1.6 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Methyltransf_31 PF13847.6 EMR72611.1 - 0.00018 21.3 0.1 0.00024 20.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMR72611.1 - 0.0002 21.2 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EMR72611.1 - 0.00023 21.8 0.2 0.0005 20.7 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.10 EMR72611.1 - 0.00097 18.9 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MetW PF07021.12 EMR72611.1 - 0.0022 17.6 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 EMR72611.1 - 0.0039 17.1 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 EMR72611.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin Methyltransf_12 PF08242.12 EMR72611.1 - 0.057 14.2 0.1 0.14 12.9 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 EMR72611.1 - 0.063 13.4 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EMR72611.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMR72611.1 - 0.27 10.5 0.0 0.31 10.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Yos1 PF08571.10 EMR72612.1 - 4.1e-33 113.5 0.2 4.5e-33 113.3 0.2 1.0 1 0 0 1 1 1 1 Yos1-like ILVD_EDD PF00920.21 EMR72614.1 - 1.4e-205 683.8 0.7 1.7e-205 683.6 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family Flavodoxin_2 PF02525.17 EMR72615.1 - 7.4e-38 130.2 0.1 8.6e-38 130.0 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EMR72615.1 - 8.1e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Exotox-A_bind PF09101.10 EMR72615.1 - 0.19 11.0 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A binding Cyclin PF08613.11 EMR72616.1 - 9e-43 146.4 0.0 2.6e-42 144.9 0.0 1.9 1 1 0 1 1 1 1 Cyclin DUF4603 PF15376.6 EMR72616.1 - 0.12 9.7 3.2 0.16 9.3 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF1541 PF07563.11 EMR72616.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Pex14_N PF04695.13 EMR72616.1 - 0.17 12.6 3.4 0.18 12.5 2.5 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_pp85 PF04637.12 EMR72616.1 - 6.5 5.0 6.1 8.6 4.6 6.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Peptidase_M24 PF00557.24 EMR72617.1 - 8.6e-56 188.9 0.0 1.1e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EMR72617.1 - 2.6e-24 85.3 0.0 4.7e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain COesterase PF00135.28 EMR72618.1 - 1.2e-74 252.0 0.0 1.7e-74 251.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family FAD_binding_4 PF01565.23 EMR72618.1 - 3.9e-26 91.4 1.1 6.6e-26 90.7 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR72618.1 - 2e-11 43.8 0.0 5.4e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_3 PF07859.13 EMR72618.1 - 3.2e-05 23.9 0.3 8.4e-05 22.5 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thaumatin PF00314.17 EMR72618.1 - 0.15 11.7 0.2 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 Thaumatin family Peptidase_S10 PF00450.22 EMR72619.1 - 5.3e-54 184.2 0.2 6.5e-54 183.9 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase adh_short_C2 PF13561.6 EMR72620.1 - 4e-56 190.2 0.3 5.1e-56 189.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR72620.1 - 3.1e-42 144.3 0.5 4e-42 143.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EMR72620.1 - 0.091 12.6 0.2 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPP_enzyme_N PF02776.18 EMR72621.1 - 3.1e-40 137.6 0.0 2.7e-39 134.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMR72621.1 - 6.4e-22 78.0 0.0 1.5e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMR72621.1 - 1.3e-10 41.2 0.0 5.6e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TcpQ PF10671.9 EMR72621.1 - 0.077 13.1 0.2 0.91 9.7 0.2 2.4 3 0 0 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q p450 PF00067.22 EMR72622.1 - 1e-49 169.5 0.0 1.5e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EMR72623.1 - 2.6e-18 66.3 2.6 4.3e-18 65.6 2.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMR72623.1 - 4.2e-17 63.4 0.6 9.2e-17 62.3 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SIS_2 PF13580.6 EMR72623.1 - 0.06 13.4 2.9 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 SIS domain ADH_N PF08240.12 EMR72623.1 - 0.12 12.3 0.0 0.45 10.4 0.0 2.0 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Peptidase_M49 PF03571.15 EMR72624.1 - 4.6e-138 461.0 0.0 2.5e-106 356.3 0.0 2.0 2 0 0 2 2 2 2 Peptidase family M49 2C_adapt PF08793.10 EMR72624.1 - 0.059 13.6 0.5 0.14 12.4 0.5 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain ECH_1 PF00378.20 EMR72625.1 - 2.4e-21 76.2 0.1 5.6e-21 75.0 0.1 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMR72625.1 - 6.2e-09 35.8 0.0 3.2e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase zf-rbx1 PF12678.7 EMR72625.1 - 1e-06 28.9 1.2 1e-06 28.9 1.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EMR72625.1 - 1.9e-06 28.1 2.7 1.9e-06 28.1 2.7 2.9 4 1 0 4 4 2 1 Ring finger domain zf-ANAPC11 PF12861.7 EMR72625.1 - 0.00025 21.0 2.4 0.00061 19.8 2.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EMR72625.1 - 0.00083 19.2 1.4 0.00083 19.2 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMR72625.1 - 0.0012 18.6 0.5 0.0012 18.6 0.5 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMR72625.1 - 0.0026 17.6 0.2 0.0026 17.6 0.2 2.3 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EMR72625.1 - 0.0028 17.6 1.1 0.0028 17.6 1.1 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMR72625.1 - 0.016 15.2 1.7 0.016 15.2 1.7 2.5 2 1 1 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EMR72625.1 - 0.024 14.8 0.4 0.088 13.0 0.4 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EMR72625.1 - 0.025 14.4 3.5 0.034 14.0 0.1 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EMR72625.1 - 0.032 14.4 0.6 0.091 13.0 0.6 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain YdjO PF14169.6 EMR72625.1 - 0.045 13.5 0.2 0.17 11.7 0.2 2.0 1 0 0 1 1 1 0 Cold-inducible protein YdjO Pellino PF04710.14 EMR72625.1 - 0.12 11.0 2.4 0.18 10.5 2.4 1.2 1 0 0 1 1 1 0 Pellino zf-RING_11 PF17123.5 EMR72625.1 - 0.21 11.4 0.0 0.21 11.4 0.0 2.9 3 0 0 3 3 2 0 RING-like zinc finger Glyco_hydro_61 PF03443.14 EMR72626.1 - 9.1e-53 179.2 0.0 1.6e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EMR72626.1 - 2.6e-12 46.5 11.0 5.5e-12 45.4 11.0 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Mucin PF01456.17 EMR72626.1 - 0.035 14.1 41.4 0.075 13.0 41.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SRPRB PF09439.10 EMR72627.1 - 1.1e-24 86.9 0.0 1.2e-23 83.5 0.0 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EMR72627.1 - 3.9e-06 26.9 0.0 5.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EMR72627.1 - 0.00022 21.7 0.6 0.00056 20.3 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMR72627.1 - 0.00062 20.0 0.1 0.0029 17.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 EMR72627.1 - 0.0014 19.1 0.1 0.0036 17.7 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EMR72627.1 - 0.0032 17.1 0.0 0.23 11.1 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EMR72627.1 - 0.0085 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EMR72627.1 - 0.016 15.8 0.0 0.04 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 EMR72627.1 - 0.02 14.3 0.1 0.82 9.1 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMR72627.1 - 0.037 13.5 0.0 0.2 11.2 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RuvB_N PF05496.12 EMR72627.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 EMR72627.1 - 0.06 13.0 0.2 5 6.7 0.0 2.6 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 EMR72627.1 - 0.083 12.3 0.1 1 8.7 0.0 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FeoB_N PF02421.18 EMR72627.1 - 0.12 11.9 0.0 12 5.4 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_5 PF07728.14 EMR72627.1 - 0.17 11.9 0.1 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PALP PF00291.25 EMR72628.1 - 3.2e-65 220.5 0.3 4.4e-65 220.0 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EMR72628.1 - 5e-12 46.1 0.0 4.7e-09 36.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain Fungal_trans PF04082.18 EMR72629.1 - 1.1e-15 57.4 2.5 1.5e-15 57.0 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMR72631.1 - 0.055 13.6 9.3 0.14 12.3 9.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR72631.1 - 0.068 12.2 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain ABC_tran_2 PF16949.5 EMR72631.1 - 0.3 9.8 0.1 0.47 9.2 0.1 1.2 1 0 0 1 1 1 0 Putative ATP-binding cassette Spt20 PF12090.8 EMR72631.1 - 0.51 9.9 14.6 0.077 12.6 6.8 2.2 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 EMR72631.1 - 0.56 10.3 20.0 4 7.6 12.3 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2183 PF09949.9 EMR72632.1 - 1.1e-34 118.7 0.0 1.4e-33 115.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Zn_clus PF00172.18 EMR72633.1 - 4.5e-06 26.7 11.3 7.1e-06 26.1 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 EMR72633.1 - 0.16 11.6 14.7 0.25 10.9 14.7 1.3 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 EMR72633.1 - 0.28 10.1 9.1 0.38 9.7 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 EMR72633.1 - 1.1 9.2 16.1 1.3 8.9 16.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FTZ PF03867.14 EMR72633.1 - 1.9 8.0 6.5 2.5 7.6 6.5 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Tsc35 PF15079.6 EMR72633.1 - 2.8 7.5 7.8 5.2 6.6 7.8 1.4 1 0 0 1 1 1 0 Testis-specific protein 35 DUF2470 PF10615.9 EMR72635.1 - 6.4e-18 65.2 0.8 9e-18 64.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 EMR72635.1 - 7.3e-05 23.0 1.8 0.00013 22.2 1.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) Zn_clus PF00172.18 EMR72636.1 - 4.3e-10 39.5 6.6 8.2e-10 38.6 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMR72636.1 - 0.0089 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Clusterin PF01093.17 EMR72636.1 - 0.36 9.8 4.1 0.6 9.1 4.1 1.2 1 0 0 1 1 1 0 Clusterin Phosphoesterase PF04185.14 EMR72637.1 - 4.1e-13 49.2 0.0 4.3e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 Phosphoesterase family Glyco_hydro_61 PF03443.14 EMR72638.1 - 1.5e-45 155.7 0.0 1e-38 133.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 CLN3 PF02487.17 EMR72639.1 - 2.6e-161 537.1 0.0 3.1e-161 536.9 0.0 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EMR72639.1 - 5.6e-09 35.4 9.0 3.7e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PQ-loop PF04193.14 EMR72640.1 - 6.2e-16 57.9 17.8 3.5e-13 49.1 1.5 3.0 3 0 0 3 3 3 2 PQ loop repeat bZIP_1 PF00170.21 EMR72641.1 - 0.02 15.0 7.6 0.02 15.0 7.6 2.8 2 1 1 3 3 3 0 bZIP transcription factor DUF5094 PF17015.5 EMR72641.1 - 0.029 14.5 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) HALZ PF02183.18 EMR72641.1 - 0.08 13.2 4.1 1.3 9.3 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper TFIIA PF03153.13 EMR72641.1 - 0.96 9.4 8.1 1.2 9.0 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PET117 PF15786.5 EMR72644.1 - 0.46 10.8 7.4 9.6 6.6 0.0 2.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Spt20 PF12090.8 EMR72644.1 - 2.3 7.8 15.2 4.4 6.9 15.2 1.4 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 EMR72644.1 - 2.4 6.9 8.6 3.7 6.3 8.6 1.4 1 0 0 1 1 1 0 Androgen receptor ILVD_EDD PF00920.21 EMR72645.1 - 7.3e-83 278.9 2.4 9.1e-83 278.6 2.4 1.1 1 0 0 1 1 1 1 Dehydratase family R3H-assoc PF13902.6 EMR72645.1 - 6e-19 68.8 2.0 7.7e-19 68.4 1.1 1.6 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 EMR72645.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 R3H domain PWI PF01480.17 EMR72646.1 - 2.7e-05 24.4 0.0 5.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 EMR72646.1 - 0.0015 18.5 0.0 0.28 11.2 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EMR72646.1 - 0.0055 16.5 0.1 0.04 13.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 EMR72646.1 - 2.7 7.2 8.2 5.1 6.4 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PHP PF02811.19 EMR72647.1 - 4.7e-12 46.5 0.0 8.3e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 PHP domain adh_short_C2 PF13561.6 EMR72648.1 - 1.3e-50 172.2 0.6 1.7e-50 171.8 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR72648.1 - 1.9e-46 158.0 2.2 2.3e-46 157.7 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR72648.1 - 0.005 16.8 0.2 0.0086 16.0 0.2 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMR72648.1 - 0.012 15.5 0.6 0.056 13.3 0.2 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EMR72648.1 - 0.07 12.6 0.2 0.22 10.9 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EMR72648.1 - 0.089 13.5 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GIDA PF01134.22 EMR72648.1 - 0.099 11.7 1.2 0.14 11.2 1.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A CbiA PF01656.23 EMR72648.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NAD_binding_1 PF00175.21 EMR72650.1 - 4e-11 43.5 0.0 8.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EMR72650.1 - 5.7e-10 39.7 0.0 9.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 EMR72650.1 - 3.5e-05 23.8 0.0 6.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protoglobin FAD_binding_6 PF00970.24 EMR72650.1 - 0.0019 18.5 0.0 0.0037 17.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EMR72650.1 - 0.0048 17.0 0.2 0.056 13.6 0.1 2.6 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_1 PF00667.20 EMR72650.1 - 0.24 10.9 0.2 0.51 9.9 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain DUF4515 PF14988.6 EMR72651.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Ribonuclease_3 PF00636.26 EMR72652.1 - 1e-15 58.2 0.5 2.2e-15 57.2 0.0 1.8 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EMR72652.1 - 6.5e-11 42.5 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EMR72652.1 - 0.0032 18.2 0.0 0.009 16.7 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF4114 PF13448.6 EMR72652.1 - 0.098 13.5 0.2 0.41 11.5 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4114) Aldo_ket_red PF00248.21 EMR72653.1 - 8e-44 150.0 0.0 1.1e-42 146.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF5572 PF17733.1 EMR72654.1 - 1.6e-14 53.5 3.1 2.8e-14 52.7 3.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Cellulase PF00150.18 EMR72655.1 - 6.9e-13 48.7 0.5 3.6e-12 46.3 0.5 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UPF0061 PF02696.14 EMR72656.1 - 1.5e-124 416.3 0.0 1.9e-124 416.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF4419 PF14388.6 EMR72656.1 - 0.17 11.3 0.4 0.27 10.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) PUF PF00806.19 EMR72657.1 - 8e-37 122.9 5.4 7.4e-08 31.7 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat ACBP PF00887.19 EMR72658.1 - 1.1e-24 86.4 0.0 3.3e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein Peptidase_S64 PF08192.11 EMR72658.1 - 0.2 10.1 0.2 0.23 9.9 0.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ge1_WD40 PF16529.5 EMR72659.1 - 0.016 14.2 0.0 0.057 12.4 0.0 1.8 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIID_20kDa PF03847.13 EMR72659.1 - 0.25 11.9 7.6 8.3 7.0 1.9 3.5 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A JHBP PF06585.11 EMR72659.1 - 0.32 10.1 1.7 1.9 7.6 0.2 2.7 3 0 0 3 3 3 0 Haemolymph juvenile hormone binding protein (JHBP) CelTOS PF18659.1 EMR72659.1 - 3 8.3 11.7 1.8 9.0 0.4 3.4 2 1 1 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites PIN_8 PF18476.1 EMR72659.1 - 3.3 7.5 14.5 2.5 7.9 2.7 3.0 2 1 0 2 2 2 0 PIN like domain DUF4611 PF15387.6 EMR72659.1 - 8.8 6.6 9.1 1.1 9.5 0.2 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) PP2C PF00481.21 EMR72660.1 - 3.5e-43 148.1 0.0 7.8e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EMR72660.1 - 0.00022 21.0 0.1 0.00078 19.1 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 EMR72660.1 - 0.00039 20.4 0.0 0.46 10.4 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Thioredoxin_15 PF18403.1 EMR72660.1 - 0.16 11.9 0.0 0.35 10.7 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Molybdopterin PF00384.22 EMR72661.1 - 1e-69 235.6 0.0 9.3e-68 229.1 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 EMR72661.1 - 1.1e-18 67.7 0.0 2.8e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal TPP_enzyme_M PF00205.22 EMR72661.1 - 0.022 14.5 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 EMR72661.1 - 0.27 11.1 1.2 7.2 6.6 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DUF2985 PF11204.8 EMR72662.1 - 8e-22 77.2 4.0 1.5e-21 76.3 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) SR-25 PF10500.9 EMR72662.1 - 4.7e-05 23.1 23.7 4.7e-05 23.1 23.7 3.3 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Proton_antipo_C PF01010.19 EMR72662.1 - 1.2 8.7 0.0 1.2 8.7 0.0 2.1 3 0 0 3 3 3 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus DUF3915 PF13054.6 EMR72662.1 - 2 8.4 5.4 6.3 6.8 5.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Menin PF05053.13 EMR72662.1 - 6.1 5.1 8.9 9.3 4.5 8.9 1.3 1 0 0 1 1 1 0 Menin Glycos_transf_1 PF00534.20 EMR72663.1 - 1.3e-21 76.9 0.0 2.6e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMR72663.1 - 3.2e-15 56.7 0.0 7.1e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EMR72663.1 - 1.1e-05 25.8 0.0 2.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 EMR72663.1 - 0.036 12.8 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 Aldolase_II PF00596.21 EMR72664.1 - 7.7e-41 140.1 1.1 9.9e-41 139.7 0.6 1.4 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain CENP-P PF13096.6 EMR72664.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P CUE PF02845.16 EMR72665.1 - 4.4e-11 42.3 0.0 7.8e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain Homeobox_KN PF05920.11 EMR72665.1 - 0.19 11.7 1.5 0.29 11.1 0.2 2.0 2 0 0 2 2 2 0 Homeobox KN domain DIL PF01843.19 EMR72666.1 - 1.9e-30 105.2 0.8 3.3e-30 104.4 0.8 1.4 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 EMR72666.1 - 3.9e-12 46.6 0.1 6.2e-11 42.7 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMR72666.1 - 4.8e-10 39.8 0.0 6.2e-05 23.5 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR72666.1 - 3.3e-08 33.7 0.0 4.6e-06 26.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EMR72666.1 - 9.9e-08 32.1 0.1 0.023 15.1 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EMR72666.1 - 2.4e-05 24.4 0.0 0.4 11.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DUF1168 PF06658.12 EMR72667.1 - 4.1e-34 117.3 14.1 4.1e-34 117.3 14.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) Cupin_2 PF07883.11 EMR72668.1 - 1.1e-08 34.6 0.0 2.2e-08 33.7 0.0 1.5 1 1 1 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EMR72668.1 - 0.0076 15.9 0.2 0.09 12.5 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF861) DnaJ PF00226.31 EMR72669.1 - 1.4e-23 82.8 2.4 3.2e-23 81.6 1.5 2.2 2 0 0 2 2 2 1 DnaJ domain Metallophos_2 PF12850.7 EMR72670.1 - 1.2e-12 48.3 0.0 1.5e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Allantoicase PF03561.15 EMR72671.1 - 4.8e-93 308.7 0.0 1.2e-45 155.0 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.16 EMR72672.1 - 1.6e-15 57.4 7.2 1.6e-15 57.4 7.2 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Rnf-Nqr PF02508.14 EMR72672.1 - 0.026 14.5 0.7 0.026 14.5 0.7 2.2 2 1 0 2 2 2 0 Rnf-Nqr subunit, membrane protein MttA_Hcf106 PF02416.16 EMR72672.1 - 0.23 10.8 6.0 0.59 9.5 6.0 1.7 1 0 0 1 1 1 0 mttA/Hcf106 family DUF1129 PF06570.11 EMR72672.1 - 0.53 9.7 11.6 0.27 10.7 8.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF2919 PF11143.8 EMR72672.1 - 1.2 9.5 9.5 0.24 11.7 3.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2919) Sdh_cyt PF01127.22 EMR72672.1 - 3.8 7.5 17.0 0.18 11.8 3.1 2.8 1 1 2 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Glyco_hydro_79C PF16862.5 EMR72673.1 - 3.2e-20 72.9 0.2 7.1e-20 71.8 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Tetraspanin PF00335.20 EMR72675.1 - 0.0056 16.4 0.1 0.01 15.6 0.1 1.6 1 1 0 1 1 1 1 Tetraspanin family RabGAP-TBC PF00566.18 EMR72676.1 - 1.7e-32 112.9 0.0 2.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DPCD PF14913.6 EMR72676.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 DPCD protein family Cpn60_TCP1 PF00118.24 EMR72677.1 - 5.6e-169 562.9 0.3 6.4e-169 562.7 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 EMR72677.1 - 0.02 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 BRK domain Shugoshin_C PF07557.11 EMR72678.1 - 4.4e-11 42.4 3.9 2.9e-10 39.8 3.9 2.6 1 0 0 1 1 1 1 Shugoshin C terminus CRM1_C PF08767.11 EMR72679.1 - 1.1e-117 392.8 2.3 1.1e-117 392.8 2.3 3.1 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 EMR72679.1 - 5.6e-40 136.8 7.0 5.6e-40 136.8 7.0 3.5 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EMR72679.1 - 3.6e-33 113.0 4.9 1e-32 111.6 4.9 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EMR72679.1 - 1.9e-27 95.1 0.8 1.9e-27 95.1 0.8 3.1 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EMR72679.1 - 1.3e-19 69.4 3.2 3.3e-19 68.1 1.1 2.7 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EMR72679.1 - 2e-15 56.4 0.9 9.8e-15 54.2 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain BID PF06393.11 EMR72679.1 - 0.019 14.5 0.2 0.065 12.8 0.2 1.9 1 0 0 1 1 1 0 BH3 interacting domain (BID) Vac14_Fab1_bd PF12755.7 EMR72679.1 - 0.055 14.1 1.4 3.5 8.3 0.0 4.3 5 0 0 5 5 4 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EMR72679.1 - 0.19 11.6 6.5 0.29 11.0 0.1 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) MMS19_C PF12460.8 EMR72679.1 - 0.57 9.2 9.7 0.68 9.0 0.1 3.9 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal HD_assoc PF13286.6 EMR72679.1 - 0.75 10.4 3.4 48 4.6 0.0 4.1 5 0 0 5 5 4 0 Phosphohydrolase-associated domain HATPase_c PF02518.26 EMR72680.1 - 1.6e-21 76.9 0.1 3.3e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMR72680.1 - 2.7e-21 75.9 0.0 1.3e-20 73.7 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EMR72680.1 - 3.7e-20 71.7 0.1 1e-19 70.3 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EMR72680.1 - 1.2e-08 35.1 0.0 0.00087 19.5 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 EMR72680.1 - 0.011 16.0 0.0 0.89 9.8 0.0 3.0 2 0 0 2 2 2 0 PAS domain PAS PF00989.25 EMR72680.1 - 0.027 14.5 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 EMR72680.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain MlaA PF04333.13 EMR72680.1 - 0.18 11.5 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 MlaA lipoprotein DUF1445 PF07286.12 EMR72681.1 - 9.4e-63 210.4 0.0 1.3e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Aminotran_5 PF00266.19 EMR72683.1 - 5.8e-26 91.3 0.0 7.1e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMR72683.1 - 0.00019 20.7 0.0 0.00039 19.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.19 EMR72683.1 - 0.0011 19.0 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 B12 binding domain HA2 PF04408.23 EMR72686.1 - 2.6e-18 66.3 0.1 7.3e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EMR72686.1 - 4e-15 56.0 0.0 9.6e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EMR72686.1 - 3.7e-12 46.6 0.0 7.4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EMR72686.1 - 1.4e-05 25.4 0.0 3.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMR72686.1 - 0.00092 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMR72686.1 - 0.003 17.9 0.0 0.012 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EMR72686.1 - 0.019 14.5 0.2 0.53 9.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 EMR72686.1 - 0.042 13.6 0.5 0.22 11.3 0.5 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 EMR72686.1 - 0.058 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EMR72686.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EMR72686.1 - 0.17 11.1 0.2 0.69 9.2 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin DASH_Dad2 PF08654.10 EMR72687.1 - 2.3e-24 85.7 0.6 2.3e-24 85.7 0.6 2.4 3 0 0 3 3 3 1 DASH complex subunit Dad2 Piwi PF02171.17 EMR72688.1 - 2.3e-62 210.9 0.6 1.1e-49 169.4 0.0 2.2 1 1 1 2 2 2 2 Piwi domain ArgoL1 PF08699.10 EMR72688.1 - 2.7e-12 46.1 0.1 1.3e-11 44.0 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoN PF16486.5 EMR72688.1 - 1.9e-10 41.5 0.1 3.5e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EMR72688.1 - 3.7e-10 40.0 0.0 3.4e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 EMR72688.1 - 1.5e-07 31.3 0.0 9.6e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 PAZ domain ArgoMid PF16487.5 EMR72688.1 - 5.3e-05 23.4 0.1 0.00013 22.2 0.1 1.6 1 0 0 1 1 1 1 Mid domain of argonaute Stn1 PF10451.9 EMR72689.1 - 3.7e-08 32.6 2.7 1.2e-05 24.4 0.1 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EMR72689.1 - 9.9e-06 25.5 0.5 2.9e-05 24.0 0.5 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Glyco_hydro81C PF17652.1 EMR72690.1 - 6.7e-163 541.9 6.9 8.3e-163 541.6 6.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EMR72690.1 - 3.4e-80 269.6 0.3 3.6e-75 253.1 0.2 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain AveC_like PF17198.4 EMR72690.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Spirocyclase AveC-like His_Phos_1 PF00300.22 EMR72691.1 - 8.6e-28 97.4 0.0 2e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1977 PF09320.11 EMR72692.1 - 3.2e-25 88.4 0.0 4.4e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) adh_short PF00106.25 EMR72693.1 - 1.1e-18 67.5 0.5 1.2e-18 67.2 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72693.1 - 4.6e-17 62.4 3.0 5.6e-17 62.1 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72693.1 - 6.3e-13 49.0 0.3 7.9e-13 48.7 0.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMR72693.1 - 2.1e-05 23.8 0.0 2.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMR72693.1 - 0.0037 16.7 0.1 0.0055 16.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EMR72694.1 - 1.4e-18 67.0 22.6 1.9e-18 66.6 22.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1996 PF09362.10 EMR72695.1 - 1.4e-63 215.1 0.2 1.7e-63 214.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short PF00106.25 EMR72696.1 - 7.4e-22 77.8 0.0 1.2e-20 73.8 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72696.1 - 1.3e-10 41.2 0.1 9.1e-10 38.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72696.1 - 1.2e-07 31.8 0.1 2.4e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EMR72696.1 - 1.6e-05 25.2 0.1 8.7e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMR72696.1 - 0.002 18.2 0.0 0.0047 17.0 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 EMR72696.1 - 0.0082 15.3 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.21 EMR72696.1 - 0.023 14.1 0.2 2.7 7.3 0.0 2.1 1 1 1 2 2 2 0 ThiF family Cu-oxidase_2 PF07731.14 EMR72697.1 - 4.1e-11 42.8 0.1 5.4e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Multicopper oxidase AAA PF00004.29 EMR72698.1 - 7.5e-18 65.2 0.0 1.5e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMR72698.1 - 0.00017 21.6 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMR72698.1 - 0.0002 21.8 0.3 0.0014 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMR72698.1 - 0.00065 20.0 0.2 0.0042 17.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EMR72698.1 - 0.0058 17.2 0.0 0.079 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zot PF05707.12 EMR72698.1 - 0.0074 15.9 0.2 0.067 12.8 0.0 2.1 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_2 PF07724.14 EMR72698.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MeaB PF03308.16 EMR72698.1 - 0.02 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EMR72698.1 - 0.036 14.3 0.1 0.25 11.6 0.0 2.4 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EMR72698.1 - 0.04 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EMR72698.1 - 0.04 13.3 0.6 0.14 11.5 0.2 1.8 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.6 EMR72698.1 - 0.055 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMR72698.1 - 0.071 12.8 0.5 0.22 11.2 0.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMR72698.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EMR72698.1 - 0.094 11.8 0.0 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 EMR72698.1 - 0.1 12.2 0.1 0.27 10.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EMR72698.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Fungal_lectin PF07938.12 EMR72699.1 - 0.0051 16.2 0.5 0.019 14.4 0.1 2.0 1 1 1 2 2 2 1 Fungal fucose-specific lectin Tim17 PF02466.19 EMR72700.1 - 5.8e-29 100.7 3.5 6.3e-29 100.6 3.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ebp2 PF05890.12 EMR72701.1 - 7.8e-95 317.5 1.9 7.8e-95 317.5 1.9 2.9 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 PIG-P PF08510.12 EMR72702.1 - 0.0037 17.2 0.1 0.0056 16.6 0.1 1.4 1 0 0 1 1 1 1 PIG-P COX15-CtaA PF02628.15 EMR72702.1 - 0.051 12.6 0.1 0.077 12.1 0.1 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Spb1_C PF07780.12 EMR72703.1 - 1.2e-83 279.9 30.7 1.2e-83 279.9 30.7 2.2 2 1 0 2 2 2 1 Spb1 C-terminal domain RFamide_26RFa PF11109.8 EMR72703.1 - 0.085 13.4 6.1 0.63 10.6 0.6 2.6 2 1 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 Fungal_trans_2 PF11951.8 EMR72704.1 - 2.2e-07 30.0 0.3 2.9e-07 29.6 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain CLAMP PF14769.6 EMR72704.1 - 0.098 13.1 0.3 0.26 11.7 0.1 1.8 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 DUF885 PF05960.11 EMR72705.1 - 1.4e-50 173.5 0.0 1.9e-50 173.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) PSII_Pbs27 PF13326.6 EMR72705.1 - 0.01 16.2 0.7 0.22 11.8 0.2 2.8 2 1 1 3 3 3 1 Photosystem II Pbs27 TcdA_TcdB PF12919.7 EMR72705.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain HMG_box PF00505.19 EMR72706.1 - 5.4e-06 26.7 0.4 1.1e-05 25.7 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Peptidase_M20 PF01546.28 EMR72707.1 - 6.7e-25 88.0 0.0 6.1e-24 84.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMR72707.1 - 2.1e-07 30.8 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 EMR72707.1 - 4.4e-06 27.3 1.3 1.4 10.0 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EMR72707.1 - 0.02 13.9 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EMR72707.1 - 0.048 14.0 0.0 0.54 10.6 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_A4 PF01828.17 EMR72708.1 - 1.5e-41 142.2 14.9 1.8e-41 141.9 14.9 1.0 1 0 0 1 1 1 1 Peptidase A4 family Tim17 PF02466.19 EMR72709.1 - 3.5e-32 111.1 7.4 4.3e-32 110.8 7.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 EMR72709.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal Asparaginase_2 PF01112.18 EMR72710.1 - 3.6e-54 183.9 0.5 1.4e-26 93.3 0.1 5.1 5 0 0 5 5 5 5 Asparaginase DUF1996 PF09362.10 EMR72711.1 - 7.1e-83 278.2 1.1 8.5e-83 277.9 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Spt5-NGN PF03439.13 EMR72712.1 - 6.8e-24 83.6 0.0 1.3e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 EMR72712.1 - 3.4e-18 66.0 27.8 4.2e-18 65.7 17.7 4.7 1 1 2 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 EMR72712.1 - 3.5e-18 66.4 15.3 3.5e-18 66.4 15.3 3.4 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EMR72712.1 - 6.2e-06 26.0 20.0 0.0023 17.8 1.3 6.0 6 0 0 6 6 6 2 KOW motif DUF3912 PF13051.6 EMR72712.1 - 0.013 15.7 0.5 0.31 11.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) Cornifin PF02389.15 EMR72712.1 - 0.15 12.3 3.6 0.29 11.3 3.6 1.4 1 0 0 1 1 1 0 Cornifin (SPRR) family Jacalin PF01419.17 EMR72713.1 - 3.2e-05 23.9 0.0 5.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Exo_endo_phos PF03372.23 EMR72713.1 - 0.00081 19.0 0.7 0.0014 18.2 0.7 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_3 PF13606.6 EMR72714.1 - 9.4e-15 53.3 0.3 0.049 14.2 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 EMR72714.1 - 4.8e-13 49.5 0.0 0.00046 20.7 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EMR72714.1 - 2e-11 43.8 2.2 0.057 13.9 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EMR72714.1 - 4.4e-10 39.9 0.3 0.041 14.5 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMR72714.1 - 4.6e-06 26.8 3.3 5.7 7.4 0.0 6.1 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Glyco_hydro_61 PF03443.14 EMR72715.1 - 4.2e-62 209.7 0.0 5.1e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4705 PF15788.5 EMR72715.1 - 0.0045 17.2 0.3 0.01 16.1 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4705) Peptidase_M22 PF00814.25 EMR72717.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.5 1 1 0 1 1 1 0 Glycoprotease family YtxH PF12732.7 EMR72717.1 - 2.3 8.8 5.7 42 4.8 5.7 2.3 1 1 0 1 1 1 0 YtxH-like protein Pyr_redox_2 PF07992.14 EMR72718.1 - 1.3e-34 119.8 0.0 1.5e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMR72718.1 - 3e-06 27.7 0.8 5.8e-06 26.8 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR72718.1 - 0.18 12.1 3.0 8.9 6.6 0.0 3.1 2 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Ank_5 PF13857.6 EMR72721.1 - 1.8e-13 50.4 0.4 0.0022 18.3 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMR72721.1 - 2.3e-13 49.0 0.1 8.5e-05 22.7 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EMR72721.1 - 2.6e-13 50.2 0.1 0.0014 19.1 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EMR72721.1 - 8.4e-13 48.1 1.0 8.5e-05 22.8 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 EMR72721.1 - 1.5e-12 47.9 0.1 3.8e-09 37.0 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Lactamase_B_6 PF16661.5 EMR72721.1 - 0.029 13.8 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain DNA_pol_B PF00136.21 EMR72722.1 - 1.1e-150 502.4 2.7 1.4e-150 502.0 2.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EMR72722.1 - 4.2e-75 253.0 0.0 9.7e-75 251.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EMR72722.1 - 3e-18 66.0 4.2 7.4e-18 64.8 4.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EMR72722.1 - 0.0012 17.8 1.9 0.0038 16.2 0.1 2.3 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 EMR72722.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 EMR72722.1 - 0.031 14.2 5.9 1.1 9.2 0.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNase_H_2 PF13482.6 EMR72722.1 - 0.053 13.5 0.2 0.46 10.5 0.2 2.5 1 1 0 1 1 1 0 RNase_H superfamily Peptidase_M48_N PF16491.5 EMR72723.1 - 7.9e-67 224.7 7.7 1.3e-66 223.9 7.7 1.4 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EMR72723.1 - 1.4e-15 57.6 0.1 5e-14 52.5 0.1 2.9 2 1 1 3 3 3 1 Peptidase family M48 DUF4538 PF15061.6 EMR72723.1 - 2.3 8.0 4.1 0.95 9.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) ELFV_dehydrog_N PF02812.18 EMR72724.1 - 7e-52 174.7 0.0 9.3e-52 174.3 0.0 1.2 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 EMR72724.1 - 1.3e-13 51.2 0.4 2e-13 50.7 0.4 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase p450 PF00067.22 EMR72725.1 - 2.4e-50 171.7 0.0 2.9e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LIM PF00412.22 EMR72729.1 - 5.7e-20 71.3 9.9 1.4e-09 38.1 0.8 2.1 2 0 0 2 2 2 2 LIM domain WRC PF08879.10 EMR72729.1 - 0.017 14.8 0.1 0.066 12.9 0.1 2.0 2 0 0 2 2 2 0 WRC TNFR_c6 PF00020.18 EMR72729.1 - 0.62 10.5 13.3 0.43 11.0 0.6 3.2 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region Lar_restr_allev PF14354.6 EMR72729.1 - 6.7 7.2 7.5 2.6 8.5 1.1 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar NAD_binding_5 PF07994.12 EMR72730.1 - 2.7e-141 470.6 0.0 3.2e-141 470.4 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EMR72730.1 - 6.4e-45 151.9 0.1 1.1e-44 151.1 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF3405 PF11885.8 EMR72731.1 - 1.5e-176 588.1 8.4 1.2e-167 558.7 0.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) MFS_1 PF07690.16 EMR72732.1 - 9.1e-36 123.5 68.8 1.9e-31 109.3 57.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 EMR72732.1 - 0.16 12.0 4.5 1.5 8.9 1.0 3.1 2 0 0 2 2 2 0 Bacteriophage P21 holin S Abhydrolase_1 PF00561.20 EMR72733.1 - 2.8e-26 92.7 0.0 3.8e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMR72733.1 - 6.2e-20 72.8 0.0 7.6e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMR72733.1 - 2.2e-07 30.4 0.0 7.7e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMR72733.1 - 2.5e-05 23.1 0.0 0.00012 20.9 0.0 1.8 2 0 0 2 2 2 1 Ndr family Abhydrolase_5 PF12695.7 EMR72733.1 - 0.0053 16.6 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 EMR72733.1 - 0.094 12.2 0.0 4 6.9 0.0 2.8 3 1 0 3 3 3 0 Esterase PHB depolymerase FSH1 PF03959.13 EMR72733.1 - 0.2 11.3 0.0 20 4.8 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Gemini_mov PF01708.16 EMR72734.1 - 0.18 11.6 0.2 0.35 10.7 0.2 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein GST_N PF02798.20 EMR72736.1 - 6e-16 58.6 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMR72736.1 - 5e-14 52.5 0.0 9.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMR72736.1 - 9.4e-14 51.4 0.2 1.5e-13 50.7 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR72736.1 - 7.3e-13 48.6 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR72736.1 - 5e-11 42.7 0.2 8e-11 42.0 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMR72736.1 - 3.9e-10 39.6 0.1 8.1e-10 38.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3067 PF11267.8 EMR72736.1 - 0.013 16.0 0.1 0.026 15.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) GST_C_6 PF17171.4 EMR72736.1 - 0.017 14.9 0.0 0.061 13.1 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LETM1 PF07766.13 EMR72738.1 - 1.8e-10 40.6 0.0 2.9e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 LETM1-like protein Pkinase PF00069.25 EMR72739.1 - 1.1e-59 202.0 0.0 1.5e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMR72739.1 - 1.9e-25 89.7 0.0 2.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMR72739.1 - 5.1e-07 29.3 0.0 8.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMR72739.1 - 0.00011 21.2 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EMR72739.1 - 0.00088 18.7 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR72739.1 - 0.0013 18.7 1.2 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF302 PF03625.14 EMR72740.1 - 1.5e-07 31.2 0.1 1.9e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF302 DUF1308 PF07000.11 EMR72741.1 - 6.8e-07 29.4 0.0 3.8e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) Putative_PNPOx PF01243.20 EMR72742.1 - 0.00061 19.9 0.0 0.01 16.0 0.0 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF892 PF05974.12 EMR72743.1 - 0.004 17.2 0.1 0.0058 16.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF892) p450 PF00067.22 EMR72744.1 - 2.5e-34 118.8 0.3 3.1e-34 118.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EMR72745.1 - 6.8e-10 39.5 0.5 8.1e-10 39.2 0.5 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3173 PF11372.8 EMR72746.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) PAP2_3 PF14378.6 EMR72747.1 - 2.7e-22 79.4 11.7 3.6e-22 79.0 11.7 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 EMR72747.1 - 3.8e-09 36.4 8.5 7.1e-09 35.5 8.5 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 EMR72747.1 - 0.016 15.7 4.2 0.042 14.4 4.2 1.7 1 0 0 1 1 1 0 PAP2 superfamily C-terminal EthD PF07110.11 EMR72748.1 - 4.7e-07 30.9 0.9 1.7e-06 29.1 0.9 1.7 1 1 0 1 1 1 1 EthD domain Glyco_hydro_17 PF00332.18 EMR72749.1 - 3.5e-10 40.0 3.0 8.8e-06 25.5 0.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Gly-zipper_YMGG PF13441.6 EMR72749.1 - 1.8e-05 24.4 7.2 4.9e-05 23.0 7.2 1.7 1 1 0 1 1 1 1 YMGG-like Gly-zipper DUF4179 PF13786.6 EMR72749.1 - 0.11 12.9 0.1 0.31 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Gly-zipper_Omp PF13488.6 EMR72749.1 - 0.23 11.5 21.0 0.23 11.5 3.7 2.4 2 0 0 2 2 2 0 Glycine zipper DUF3169 PF11368.8 EMR72749.1 - 1.2 8.6 3.7 0.38 10.2 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Rick_17kDa_Anti PF05433.15 EMR72749.1 - 2.1 8.3 26.0 0.09 12.7 2.6 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Uds1 PF15456.6 EMR72750.1 - 0.01 16.0 0.3 0.015 15.4 0.0 1.5 2 0 0 2 2 2 0 Up-regulated During Septation Dynamitin PF04912.14 EMR72750.1 - 0.038 13.3 1.3 0.097 12.0 0.2 1.9 2 0 0 2 2 2 0 Dynamitin FlaC_arch PF05377.11 EMR72750.1 - 3.8 8.0 6.1 1.4 9.4 1.8 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Dioxygenase_C PF00775.21 EMR72752.1 - 2.3e-31 108.6 0.0 1.4e-24 86.5 0.0 2.1 1 1 1 2 2 2 2 Dioxygenase Polysacc_deac_1 PF01522.21 EMR72753.1 - 8.3e-17 61.2 0.1 6e-16 58.5 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EMR72753.1 - 1.6e-06 28.4 19.5 1.6e-06 28.4 19.5 3.1 3 1 0 3 3 3 1 Chitin recognition protein Glyco_hydro_57 PF03065.15 EMR72753.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Phos_pyr_kin PF08543.12 EMR72754.1 - 4.9e-81 271.7 0.1 6.4e-81 271.3 0.1 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EMR72754.1 - 1.2e-23 84.0 0.0 1.4e-21 77.3 0.0 3.0 1 1 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EMR72754.1 - 7.8e-08 32.0 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 EMR72754.1 - 0.013 14.9 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 EMR72754.1 - 0.27 10.7 1.6 1.4 8.4 1.6 2.1 1 1 0 1 1 1 0 Carbohydrate kinase HMA PF00403.26 EMR72755.1 - 1.9e-15 57.1 0.3 5.6e-15 55.5 0.1 1.9 2 0 0 2 2 2 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EMR72755.1 - 1.9e-07 31.4 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transthyretin PF00576.21 EMR72756.1 - 0.13 13.0 0.1 0.57 10.9 0.0 2.0 2 0 0 2 2 2 0 HIUase/Transthyretin family DUF4699 PF15770.5 EMR72756.1 - 6.8 6.4 8.5 9.3 5.9 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) RICTOR_N PF14664.6 EMR72757.1 - 1.7e-76 257.7 3.3 3.9e-59 200.5 0.6 3.1 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EMR72757.1 - 3.6e-39 132.7 0.0 1.8e-36 124.0 0.0 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EMR72757.1 - 1.6e-37 128.2 0.0 5.2e-36 123.3 0.0 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EMR72757.1 - 1.3e-28 99.0 0.5 3.5e-26 91.2 0.1 3.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EMR72757.1 - 3.3e-11 43.1 6.4 8.9e-11 41.8 6.4 1.8 1 0 0 1 1 1 1 Hr1 repeat THOC7 PF05615.13 EMR72757.1 - 0.019 15.3 4.6 0.046 14.0 4.6 1.6 1 0 0 1 1 1 0 Tho complex subunit 7 GPS2_interact PF15784.5 EMR72757.1 - 4 8.0 8.1 0.24 11.8 2.4 1.9 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain PIEZO PF15917.5 EMR72757.1 - 8.8 5.7 6.1 0.73 9.3 1.3 1.6 2 0 0 2 2 2 0 Piezo DEAD PF00270.29 EMR72758.1 - 2.4e-50 170.7 0.0 2.9e-49 167.2 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EMR72758.1 - 1.3e-05 25.2 0.0 4e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 EMR72758.1 - 0.052 13.4 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_22 PF13401.6 EMR72758.1 - 0.62 10.3 1.8 37 4.6 0.0 3.0 2 1 0 3 3 3 0 AAA domain TPR_1 PF00515.28 EMR72759.1 - 4.6e-15 54.7 5.1 1.5e-07 30.9 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMR72759.1 - 1.1e-12 47.0 7.8 2.8e-05 23.9 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMR72759.1 - 4e-10 39.1 2.2 0.00011 22.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMR72759.1 - 4.1e-09 36.6 0.1 6.9e-06 26.3 0.0 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.24 EMR72759.1 - 3.6e-08 33.2 0.1 6.3e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.6 EMR72759.1 - 7.1e-07 28.8 0.3 8.2e-05 22.4 0.0 3.3 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMR72759.1 - 8.9e-07 29.2 2.8 1.4 9.8 0.0 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMR72759.1 - 6e-06 25.8 2.5 0.00019 21.1 0.1 3.6 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 EMR72759.1 - 0.00024 21.2 0.3 0.48 10.6 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMR72759.1 - 0.0013 19.0 0.1 2.4 8.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMR72759.1 - 0.035 14.7 0.3 1.4 9.6 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMR72759.1 - 0.048 14.5 0.2 0.79 10.7 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMR72759.1 - 0.11 13.2 0.0 46 5.1 0.0 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMR72759.1 - 0.28 11.1 1.2 2.5 8.1 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L13 PF00572.18 EMR72760.1 - 5.5e-41 139.7 0.0 8.1e-41 139.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 EMR72761.1 - 6e-75 249.8 0.1 9.7e-40 135.9 0.1 2.0 2 0 0 2 2 2 2 Uricase MIase PF02426.16 EMR72763.1 - 0.044 13.9 0.0 0.58 10.4 0.0 2.6 2 0 0 2 2 2 0 Muconolactone delta-isomerase Polysacc_lyase PF14099.6 EMR72764.1 - 2.5e-45 154.9 9.4 2.9e-45 154.7 9.4 1.0 1 0 0 1 1 1 1 Polysaccharide lyase DUF5301 PF17225.3 EMR72765.1 - 0.078 13.4 4.3 0.22 12.0 2.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) DUF2052 PF09747.9 EMR72765.1 - 5.5 7.1 12.7 0.38 10.8 6.9 1.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Fungal_trans PF04082.18 EMR72766.1 - 7e-26 90.8 0.0 1.4e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Helo_like_N PF17111.5 EMR72767.1 - 1.2e-06 28.1 0.0 2.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins zf-C4H2 PF10146.9 EMR72767.1 - 0.48 10.7 4.6 0.93 9.8 4.6 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein MARVEL PF01284.23 EMR72768.1 - 0.00019 21.5 10.1 0.00041 20.4 10.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain TMEM132D_C PF15706.5 EMR72768.1 - 0.2 11.4 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Peptidase_M41 PF01434.18 EMR72769.1 - 1.5e-62 210.9 0.0 2.3e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EMR72769.1 - 1.9e-42 144.8 0.0 5.5e-42 143.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 EMR72769.1 - 9.4e-11 42.0 0.0 3e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_lid_3 PF17862.1 EMR72769.1 - 4e-09 36.1 0.3 1.2e-08 34.6 0.1 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EMR72769.1 - 0.0013 18.7 0.0 0.0048 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMR72769.1 - 0.0018 18.1 0.1 0.006 16.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMR72769.1 - 0.0063 16.8 0.4 0.57 10.4 0.1 3.0 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 EMR72769.1 - 0.0067 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EMR72769.1 - 0.0075 16.7 0.1 0.19 12.1 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EMR72769.1 - 0.017 15.2 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EMR72769.1 - 0.037 14.4 0.1 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EMR72769.1 - 0.063 12.7 0.3 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EMR72769.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EMR72769.1 - 0.21 11.7 0.7 0.42 10.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EMR72769.1 - 0.25 10.9 0.5 0.93 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain SspO PF08175.12 EMR72769.1 - 2.1 8.9 4.6 7.6 7.1 3.3 2.6 2 0 0 2 2 2 0 Small acid-soluble spore protein O family Pex14_N PF04695.13 EMR72769.1 - 5.1 7.7 9.0 0.55 10.9 0.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IGPD PF00475.18 EMR72771.1 - 1.7e-60 203.5 0.5 2.5e-60 203.0 0.5 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PGA2 PF07543.12 EMR72772.1 - 2.1e-45 154.1 3.1 2.4e-45 153.9 3.1 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 RGS-like PF09128.11 EMR72772.1 - 0.11 12.2 1.5 0.14 11.8 1.5 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Ribosomal_L37 PF08561.10 EMR72772.1 - 1.2 9.7 8.4 1.4 9.4 7.7 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF4428 PF14471.6 EMR72773.1 - 0.013 15.4 0.0 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C3HC4_5 PF17121.5 EMR72773.1 - 0.029 14.3 0.9 0.062 13.2 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HbrB PF08539.11 EMR72773.1 - 0.033 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 HbrB-like zinc_ribbon_12 PF11331.8 EMR72773.1 - 0.31 10.9 4.8 1.1 9.1 0.1 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain ZZ PF00569.17 EMR72773.1 - 0.8 9.6 3.5 3.1 7.7 0.5 2.7 3 0 0 3 3 3 0 Zinc finger, ZZ type DUF3039 PF11238.8 EMR72773.1 - 4.3 7.2 6.7 50 3.8 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3039) SAP PF02037.27 EMR72775.1 - 1.9e-13 49.8 0.1 3.6e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EMR72775.1 - 6.7e-07 29.0 7.3 7.2e-07 28.9 2.9 2.4 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain ASFV_J13L PF05568.11 EMR72775.1 - 0.28 10.9 6.2 0.45 10.2 6.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein FSIP2 PF15783.5 EMR72775.1 - 0.53 8.1 0.8 0.63 7.9 0.8 1.0 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 CDC27 PF09507.10 EMR72775.1 - 1.9 7.8 23.8 2.4 7.4 23.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Plasmodium_Vir PF05795.11 EMR72775.1 - 2.8 7.3 5.2 3.4 7.0 5.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DAO PF01266.24 EMR72776.1 - 5.4e-59 200.5 4.1 2.9e-58 198.1 4.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Sporozoite_P67 PF05642.11 EMR72776.1 - 0.00098 17.3 3.6 0.00098 17.3 3.6 1.3 2 0 0 2 2 2 1 Sporozoite P67 surface antigen NAD_binding_8 PF13450.6 EMR72776.1 - 0.011 15.9 0.5 0.044 14.0 0.5 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SUIM_assoc PF16619.5 EMR72776.1 - 0.12 12.4 9.3 1.2 9.3 2.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pyr_redox PF00070.27 EMR72776.1 - 0.13 12.9 0.0 14 6.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyridoxal_deC PF00282.19 EMR72778.1 - 5.2e-38 130.7 0.0 1.5e-26 93.0 0.0 2.2 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Hus1 PF04005.12 EMR72779.1 - 6e-78 261.9 0.0 7.4e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DAO PF01266.24 EMR72781.1 - 3.4e-39 135.4 0.0 3.9e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMR72781.1 - 3.1e-06 26.6 0.0 0.0099 15.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR72781.1 - 0.00017 21.7 0.0 0.00046 20.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMR72781.1 - 0.00018 21.6 0.2 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EMR72781.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Sacchrp_dh_NADP PF03435.18 EMR72781.1 - 0.028 14.7 0.0 0.14 12.4 0.0 2.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain K_oxygenase PF13434.6 EMR72781.1 - 0.03 13.5 0.0 0.063 12.4 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EMR72781.1 - 0.038 13.1 0.2 0.089 11.9 0.2 1.6 1 1 0 1 1 1 0 FAD binding domain FH2 PF02181.23 EMR72782.1 - 2.6e-85 286.8 4.7 2.6e-85 286.8 4.7 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EMR72782.1 - 4.9e-63 212.1 0.9 1.3e-62 210.7 0.1 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EMR72782.1 - 2.6e-51 174.1 1.7 2.6e-51 174.1 1.7 2.8 2 1 1 3 3 3 1 Diaphanous FH3 Domain Zn_clus PF00172.18 EMR72783.1 - 0.058 13.5 10.5 0.1 12.8 10.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec16_C PF12931.7 EMR72784.1 - 1.6e-84 284.2 0.4 3.5e-60 204.2 0.0 2.1 1 1 1 2 2 2 2 Sec23-binding domain of Sec16 DUF4892 PF16234.5 EMR72784.1 - 0.024 14.1 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) DUF5427 PF10310.9 EMR72784.1 - 0.14 11.1 1.7 0.24 10.3 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MFS_1 PF07690.16 EMR72785.1 - 4.6e-31 108.0 47.7 4.6e-31 108.0 47.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily RPE65 PF03055.15 EMR72786.1 - 5.3e-64 217.1 0.1 6.7e-49 167.3 0.0 2.0 2 0 0 2 2 2 2 Retinal pigment epithelial membrane protein SDA1 PF05285.12 EMR72787.1 - 0.0075 15.7 5.1 0.0086 15.5 5.1 1.1 1 0 0 1 1 1 1 SDA1 GSHPx PF00255.19 EMR72788.1 - 2.3e-39 133.3 0.1 2.9e-39 133.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.6 EMR72788.1 - 0.013 16.0 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) AhpC-TSA PF00578.21 EMR72788.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Sec16_N PF12935.7 EMR72789.1 - 4.6e-13 49.9 24.0 4.6e-13 49.9 24.0 2.9 2 2 0 2 2 2 1 Vesicle coat trafficking protein Sec16 N-terminus NuDC PF16273.5 EMR72789.1 - 0.043 14.3 0.9 0.043 14.3 0.9 2.4 2 0 0 2 2 2 0 Nuclear distribution C domain T5orf172 PF10544.9 EMR72790.1 - 1.9e-22 79.7 1.1 7.1e-22 77.9 0.0 2.4 2 1 1 3 3 3 1 T5orf172 domain MUG113 PF13455.6 EMR72790.1 - 1.2e-21 77.2 0.0 1.2e-21 77.2 0.0 2.2 3 0 0 3 3 3 1 Meiotically up-regulated gene 113 zf-RING_2 PF13639.6 EMR72792.1 - 2.2e-07 31.1 4.4 5.1e-07 29.9 4.4 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EMR72792.1 - 1.3e-05 24.9 0.1 3.2e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMR72792.1 - 0.00045 20.2 2.2 0.00045 20.2 2.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger BSP_II PF05432.11 EMR72792.1 - 0.0015 18.3 2.0 0.0019 17.9 2.0 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) FANCL_C PF11793.8 EMR72792.1 - 0.016 15.4 4.8 0.077 13.2 4.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 EMR72792.1 - 0.027 14.4 3.4 0.073 13.0 3.4 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 EMR72792.1 - 0.084 13.2 8.4 0.47 10.8 8.4 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain CENP-B_dimeris PF09026.10 EMR72792.1 - 0.14 12.6 6.3 0.31 11.5 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EMR72792.1 - 0.61 9.4 4.4 1 8.6 4.4 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3774 PF12609.8 EMR72792.1 - 0.9 10.6 3.7 3.9 8.6 3.7 2.0 1 1 0 1 1 1 0 Wound-induced protein Presenilin PF01080.17 EMR72792.1 - 1.8 7.3 2.9 2.1 7.0 2.9 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 EMR72792.1 - 3 5.8 4.6 3.6 5.6 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-C3HC4_3 PF13920.6 EMR72792.1 - 4.5 7.2 11.3 1.7e+02 2.2 11.3 2.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMR72792.1 - 4.7 7.2 9.8 24 4.9 3.0 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EMR72792.1 - 4.9 7.4 9.8 2.9 8.1 2.9 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EMR72792.1 - 7.9 6.4 11.9 16 5.5 6.3 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_76 PF03663.14 EMR72793.1 - 9.8e-54 183.3 7.4 1.2e-53 183.0 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RNase_H PF00075.24 EMR72794.1 - 1.1e-11 45.2 0.2 3.8e-06 27.1 0.1 2.2 1 1 1 2 2 2 2 RNase H CENP-B_dimeris PF09026.10 EMR72795.1 - 0.0043 17.4 0.3 0.0043 17.4 0.3 2.0 2 0 0 2 2 2 1 Centromere protein B dimerisation domain CorA PF01544.18 EMR72795.1 - 0.011 15.0 2.0 0.041 13.2 0.3 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Asp PF00026.23 EMR72796.1 - 3.6e-32 112.1 0.2 4.6e-32 111.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMR72796.1 - 6.1e-05 23.3 2.9 0.0041 17.4 2.9 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Fungal_trans PF04082.18 EMR72797.1 - 3e-09 36.3 0.0 5.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 EMR72798.1 - 4.1e-85 286.3 19.5 4.7e-85 286.1 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMR72798.1 - 2e-15 56.6 31.7 7.2e-15 54.8 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4418 PF14387.6 EMR72798.1 - 8.1 6.7 10.7 11 6.3 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4418) MFS_1 PF07690.16 EMR72799.1 - 2.5e-14 53.0 4.2 2.5e-14 53.0 4.2 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EMR72799.1 - 2.8e-06 27.0 2.5 8.3e-06 25.5 2.5 1.7 1 0 0 1 1 1 1 Nodulin-like SR-25 PF10500.9 EMR72799.1 - 0.012 15.3 5.3 0.019 14.6 5.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nucleo_P87 PF07267.11 EMR72799.1 - 0.21 10.4 1.3 0.34 9.7 1.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 EMR72799.1 - 0.25 9.6 1.0 0.34 9.1 0.1 1.6 2 0 0 2 2 2 0 CDC45-like protein MRC1 PF09444.10 EMR72799.1 - 1.8 9.1 12.8 4.7 7.7 5.2 2.3 2 0 0 2 2 2 0 MRC1-like domain Thr_synth_N PF14821.6 EMR72800.1 - 3.6e-28 97.6 0.0 1.1e-27 96.1 0.0 1.9 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EMR72800.1 - 3.8e-18 65.9 0.0 1.9e-17 63.6 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 EMR72801.1 - 5e-23 81.6 35.2 2.8e-22 79.1 35.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2304 PF10066.9 EMR72801.1 - 0.072 13.3 6.9 0.41 10.9 0.1 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) COesterase PF00135.28 EMR72802.1 - 9.8e-86 288.6 0.0 1.3e-85 288.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR72802.1 - 0.0026 17.6 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMR72803.1 - 2.2e-78 264.4 0.0 2.8e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMR72803.1 - 0.00023 21.1 0.2 0.002 18.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold FMO-like PF00743.19 EMR72805.1 - 3.2e-39 134.8 0.0 3.4e-23 81.9 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMR72805.1 - 1.8e-14 53.7 0.0 3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMR72805.1 - 6.8e-14 51.8 0.5 7.8e-10 38.5 0.0 3.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMR72805.1 - 1e-08 35.4 0.0 1.5e-07 31.5 0.0 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EMR72805.1 - 1.3e-07 31.1 0.2 4.9e-06 25.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EMR72805.1 - 6.8e-06 25.5 0.0 0.00082 18.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EMR72805.1 - 8.4e-06 25.6 0.1 0.36 10.4 0.1 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR72805.1 - 9.9e-06 25.7 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMR72805.1 - 0.0027 18.2 0.3 8 7.1 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EMR72805.1 - 0.039 12.7 0.0 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 MCRA family HI0933_like PF03486.14 EMR72805.1 - 0.058 12.1 0.3 0.38 9.4 0.1 2.2 3 0 0 3 3 3 0 HI0933-like protein TEX12 PF15219.6 EMR72805.1 - 0.077 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Testis-expressed 12 DUF2207 PF09972.9 EMR72807.1 - 0.089 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4381 PF14316.6 EMR72807.1 - 0.1 12.9 0.3 0.19 12.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TPP_enzyme_N PF02776.18 EMR72808.1 - 6.4e-26 91.0 0.1 2.2e-25 89.2 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMR72808.1 - 6.2e-18 65.0 0.0 3.9e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMR72808.1 - 3.3e-07 30.1 0.0 1.7e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain K_channel_TID PF07941.11 EMR72808.1 - 0.062 13.8 4.7 0.14 12.7 4.7 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain U3_assoc_6 PF08640.11 EMR72809.1 - 6.9e-25 86.9 0.2 2.6e-24 85.1 0.1 2.1 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 EMR72809.1 - 8.3e-05 21.9 0.3 0.00018 20.8 0.1 1.6 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EMR72809.1 - 0.00063 20.4 0.2 4.8 8.3 0.0 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat SIN1 PF05422.12 EMR72809.1 - 0.024 15.2 0.5 0.045 14.3 0.5 1.4 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Cellulase PF00150.18 EMR72810.1 - 1.3e-14 54.3 0.0 3.4e-14 53.0 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_76 PF03663.14 EMR72811.1 - 1.7e-39 136.4 7.3 1.1e-26 94.2 0.2 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMR72811.1 - 2.1e-05 23.8 0.0 0.00039 19.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EMR72811.1 - 0.0016 17.0 0.0 0.013 14.0 0.0 2.3 2 1 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 DUF515 PF04415.12 EMR72811.1 - 0.21 9.9 1.1 0.34 9.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) EVE PF01878.18 EMR72812.1 - 3.5e-47 160.0 0.1 3.5e-47 160.0 0.1 1.7 2 0 0 2 2 2 1 EVE domain Suf PF05843.14 EMR72812.1 - 0.083 12.9 4.0 0.19 11.7 3.7 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RNA_pol_Rbc25 PF08292.12 EMR72812.1 - 0.42 10.9 4.2 0.89 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 CI-B14_5a PF07347.12 EMR72812.1 - 1.4 8.8 10.1 3.2 7.7 3.0 3.4 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ndc1_Nup PF09531.10 EMR72812.1 - 2.1 6.9 5.2 2.2 6.8 5.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EMR72812.1 - 9 4.9 7.7 11 4.7 7.7 1.1 1 0 0 1 1 1 0 Presenilin Nucleoporin_FG PF13634.6 EMR72814.1 - 0.0014 19.4 25.8 0.0014 19.4 25.8 5.5 1 1 4 5 5 5 3 Nucleoporin FG repeat region MFS_1 PF07690.16 EMR72815.1 - 9.4e-50 169.5 62.5 1.2e-43 149.4 44.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMR72815.1 - 5e-19 68.2 9.4 9.1e-19 67.3 9.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMR72815.1 - 8.8e-13 47.9 26.5 4.4e-12 45.6 12.8 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter DJ-1_PfpI PF01965.24 EMR72816.1 - 7.5e-11 42.1 0.0 1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family PRIMA1 PF16101.5 EMR72817.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SIT PF15330.6 EMR72817.1 - 0.025 15.0 0.0 0.068 13.6 0.0 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Acetyltransf_1 PF00583.25 EMR72819.1 - 0.00016 21.9 0.0 0.00021 21.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMR72819.1 - 0.0081 16.6 0.1 0.011 16.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMR72819.1 - 0.026 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.22 EMR72820.1 - 8e-55 186.4 0.0 1.2e-54 185.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S10 PF00338.22 EMR72822.1 - 2.5e-25 88.6 0.2 2.9e-25 88.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Exo_endo_phos PF03372.23 EMR72823.1 - 0.0025 17.4 0.0 0.0037 16.8 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family p450 PF00067.22 EMR72824.1 - 1.7e-39 135.9 0.0 5.5e-27 94.6 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 CUE PF02845.16 EMR72825.1 - 1.1e-07 31.4 0.2 1.9e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 CUE domain SEP PF08059.13 EMR72825.1 - 0.13 12.9 0.3 25 5.5 0.1 2.6 2 0 0 2 2 2 0 SEP domain NOA36 PF06524.12 EMR72825.1 - 0.15 11.3 4.3 0.28 10.5 4.3 1.3 1 0 0 1 1 1 0 NOA36 protein AA_permease PF00324.21 EMR72826.1 - 2.5e-138 461.7 43.7 6.5e-138 460.3 43.7 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMR72826.1 - 6.3e-36 124.1 39.2 8.2e-36 123.7 39.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 EMR72826.1 - 0.0071 15.2 3.2 0.088 11.6 1.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4781) Sortilin-Vps10 PF15902.5 EMR72828.1 - 7.7e-290 961.0 16.4 5.8e-151 503.3 2.4 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EMR72828.1 - 1e-89 299.3 23.2 4.5e-47 160.5 8.2 3.1 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EMR72828.1 - 2.3e-08 32.8 47.4 0.17 12.0 0.4 12.5 12 0 0 12 12 12 5 BNR/Asp-box repeat BNR_2 PF13088.6 EMR72828.1 - 2.6e-08 33.5 7.1 2 7.6 0.2 6.5 5 1 1 6 6 6 4 BNR repeat-like domain BNR_6 PF15899.5 EMR72828.1 - 0.0012 18.7 2.5 12 6.2 0.0 6.1 6 0 0 6 6 6 1 BNR-Asp box repeat CHB_HEX_C PF03174.13 EMR72828.1 - 0.0026 17.7 2.5 1.4 8.9 0.0 4.4 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF2561 PF10812.8 EMR72828.1 - 0.039 14.0 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) PSII_BNR PF14870.6 EMR72828.1 - 0.079 12.2 6.4 0.3 10.3 0.3 4.1 5 0 0 5 5 5 0 Photosynthesis system II assembly factor YCF48 preSET_CXC PF18264.1 EMR72828.1 - 9 6.9 9.2 4.1 8.0 0.6 2.8 2 0 0 2 2 2 0 CXC domain Glyco_hydro_47 PF01532.20 EMR72829.1 - 4.6e-169 563.1 0.2 5.7e-169 562.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ints3 PF10189.9 EMR72829.1 - 0.18 11.0 0.0 10 5.3 0.0 2.2 1 1 1 2 2 2 0 Integrator complex subunit 3 ABC_membrane_2 PF06472.15 EMR72830.1 - 1.5e-62 211.5 0.9 2.3e-42 145.3 0.0 2.4 1 1 1 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EMR72830.1 - 7.4e-18 65.4 0.0 1.4e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMR72830.1 - 0.00023 21.1 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMR72830.1 - 0.036 14.6 0.1 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMR72830.1 - 0.043 14.2 0.6 0.28 11.5 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EMR72830.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 EMR72830.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 EMR72830.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EMR72830.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EMR72830.1 - 0.18 11.2 0.1 0.47 9.8 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Amidohydro_1 PF01979.20 EMR72831.1 - 2.6e-41 142.1 0.2 3.3e-41 141.8 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMR72831.1 - 2.9e-16 60.0 0.1 4.5e-12 46.2 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family U79_P34 PF03064.16 EMR72831.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TPR_10 PF13374.6 EMR72832.1 - 0.69 9.9 3.2 7.1 6.6 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 EMR72833.1 - 6.4e-30 104.6 0.4 9.5e-29 100.7 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR72833.1 - 1.4e-07 31.1 0.0 2e-05 24.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMR72833.1 - 8.1e-07 28.6 0.8 0.00016 21.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMR72833.1 - 1.9e-06 28.0 0.0 4.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMR72833.1 - 1.9e-06 27.2 0.8 0.011 14.8 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 EMR72833.1 - 9.7e-06 25.0 0.1 0.00017 20.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EMR72833.1 - 1.1e-05 25.0 0.0 2.8e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMR72833.1 - 2e-05 23.5 0.1 0.0068 15.2 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.14 EMR72833.1 - 2.5e-05 23.4 0.2 4.5e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Amino_oxidase PF01593.24 EMR72833.1 - 3.1e-05 23.4 0.1 0.15 11.3 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EMR72833.1 - 3.2e-05 24.4 0.4 0.001 19.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMR72833.1 - 3.3e-05 23.6 0.5 7.3e-05 22.5 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMR72833.1 - 0.002 17.3 1.1 0.0033 16.6 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EMR72833.1 - 0.026 13.6 0.2 0.11 11.5 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EMR72833.1 - 0.07 13.1 0.2 5.1 7.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EMR72833.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EMR72833.1 - 0.15 12.3 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain zf-CSL PF05207.13 EMR72834.1 - 1.3e-22 79.3 1.0 1.6e-22 79.0 1.0 1.1 1 0 0 1 1 1 1 CSL zinc finger ThrE PF06738.12 EMR72835.1 - 2e-66 223.8 21.0 2.8e-63 213.5 1.3 2.5 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EMR72835.1 - 3.4e-11 43.4 12.1 3.4e-11 43.4 12.1 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE adh_short PF00106.25 EMR72836.1 - 8.8e-33 113.4 0.6 1.8e-32 112.4 0.6 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72836.1 - 1.1e-22 80.8 1.1 2.6e-22 79.6 1.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72836.1 - 1.8e-10 41.0 0.2 2.3e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EMR72836.1 - 0.00014 22.2 0.4 0.00029 21.1 0.3 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EMR72836.1 - 0.00015 21.3 0.9 0.0011 18.5 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR72836.1 - 0.0023 17.8 3.3 0.012 15.5 3.3 1.9 1 1 0 1 1 1 1 NAD(P)H-binding LDcluster4 PF18306.1 EMR72836.1 - 0.059 13.0 0.5 0.11 12.1 0.5 1.5 1 0 0 1 1 1 0 SLOG cluster4 family DUF5368 PF17336.2 EMR72836.1 - 0.17 12.1 0.1 0.42 10.8 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5368) MFS_1 PF07690.16 EMR72837.1 - 2.6e-17 62.8 24.9 1.2e-07 31.0 0.5 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily PLDc_N PF13396.6 EMR72837.1 - 0.0042 17.0 1.6 0.018 15.0 0.8 2.6 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal RNase_H PF00075.24 EMR72838.1 - 1e-13 51.7 0.2 1.9e-13 50.8 0.2 1.5 1 0 0 1 1 1 1 RNase H G-gamma PF00631.22 EMR72838.1 - 0.02 14.9 0.1 0.041 13.9 0.1 1.5 1 0 0 1 1 1 0 GGL domain DUF2156 PF09924.9 EMR72838.1 - 0.026 13.5 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) DUF4443 PF14544.6 EMR72839.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) Perilipin PF03036.16 EMR72839.1 - 0.075 12.0 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Perilipin family PET10 PF17316.2 EMR72839.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Petite colonies protein 10 Med29 PF11568.8 EMR72840.1 - 0.059 13.6 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 Mediator complex subunit 29 Coprogen_oxidas PF01218.18 EMR72841.1 - 2.1e-143 476.5 0.0 2.3e-143 476.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase N2227 PF07942.12 EMR72842.1 - 8.6e-55 185.8 0.0 1.6e-54 184.9 0.0 1.5 1 1 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 EMR72842.1 - 5.6e-05 23.7 0.0 0.00065 20.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMR72842.1 - 0.0046 17.7 0.0 0.033 14.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMR72842.1 - 0.01 16.5 0.0 0.37 11.5 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EMR72842.1 - 0.02 14.7 0.1 0.14 11.9 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMR72842.1 - 0.024 14.5 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NFRKB_winged PF14465.6 EMR72842.1 - 0.068 13.4 0.6 1.1 9.5 0.0 2.9 2 1 0 3 3 3 0 NFRKB Winged Helix-like COMP PF11598.8 EMR72843.1 - 0.14 12.6 1.6 0.42 11.1 1.6 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Tho2 PF11262.8 EMR72843.1 - 2.2 7.4 8.9 5.6 6.1 8.9 1.7 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMPIT PF07851.13 EMR72843.1 - 3.6 6.8 8.9 3.5 6.8 7.4 1.7 1 1 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 EMR72843.1 - 8.8 5.1 9.8 13 4.5 9.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 EMR72843.1 - 9.2 6.5 9.2 16 5.7 6.8 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Glyoxalase_6 PF18029.1 EMR72845.1 - 0.0053 17.5 0.4 0.0066 17.2 0.4 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EMR72845.1 - 0.0071 16.5 0.1 0.029 14.6 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Kinesin PF00225.23 EMR72846.1 - 7e-67 225.7 1.2 7e-67 225.7 1.2 1.7 2 0 0 2 2 2 1 Kinesin motor domain Glyco_transf_8 PF01501.20 EMR72846.1 - 0.038 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 Microtub_bd PF16796.5 EMR72846.1 - 0.11 12.4 4.0 0.64 9.9 0.0 2.6 3 0 0 3 3 3 0 Microtubule binding DUF1840 PF08895.11 EMR72846.1 - 0.67 10.3 7.3 0.61 10.4 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF4337 PF14235.6 EMR72846.1 - 0.74 9.9 5.1 1.7 8.7 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Tho2 PF11262.8 EMR72846.1 - 8.5 5.5 10.3 15 4.7 10.3 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 p450 PF00067.22 EMR72847.1 - 1.3e-70 238.4 0.0 1.5e-70 238.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3045 PF11243.8 EMR72847.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) DUF3074 PF11274.8 EMR72848.1 - 2.3e-44 151.6 0.0 3.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) tRNA-synt_1 PF00133.22 EMR72849.1 - 1.4e-226 753.4 2.8 2.5e-225 749.3 2.8 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMR72849.1 - 1.2e-30 106.5 0.8 1.2e-30 106.5 0.8 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMR72849.1 - 2e-13 49.8 0.3 3.3e-05 22.8 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EMR72849.1 - 1.1e-10 41.3 7.1 4.6e-08 32.8 0.0 3.4 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 EMR72849.1 - 5.7e-05 23.3 2.7 5.7e-05 23.3 2.7 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 EMR72849.1 - 0.051 12.9 0.0 0.47 9.8 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain PepSY PF03413.19 EMR72849.1 - 1.2 9.7 4.8 0.54 10.8 0.1 2.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Stk19 PF10494.9 EMR72850.1 - 1.8e-73 247.2 0.0 2.1e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 MarR_2 PF12802.7 EMR72850.1 - 0.08 12.9 0.5 0.33 10.9 0.1 2.3 3 0 0 3 3 3 0 MarR family LexA_DNA_bind PF01726.16 EMR72850.1 - 0.1 12.4 0.5 0.35 10.7 0.0 2.1 3 0 0 3 3 3 0 LexA DNA binding domain NodZ PF05830.11 EMR72851.1 - 0.17 10.6 0.1 12 4.5 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) WD40 PF00400.32 EMR72852.1 - 0.0026 18.5 0.3 6.9 7.7 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMR72852.1 - 0.037 14.3 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Metallophos PF00149.28 EMR72853.1 - 1.5e-35 123.6 0.1 2.3e-35 123.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMR72853.1 - 1.3e-15 57.6 0.1 2.3e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SUR7 PF06687.12 EMR72854.1 - 5.9e-31 107.8 12.3 8.7e-31 107.2 12.3 1.3 1 0 0 1 1 1 1 SUR7/PalI family WD40 PF00400.32 EMR72855.1 - 3.5e-10 40.3 0.6 0.016 16.1 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat NPL PF17800.1 EMR72855.1 - 0.057 14.0 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin-like domain Myc_N PF01056.18 EMR72855.1 - 0.14 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NAD_binding_4 PF07993.12 EMR72857.1 - 6.4e-32 110.7 0.0 9.5e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EMR72857.1 - 1.3e-10 41.2 0.0 3.2e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMR72857.1 - 1.5e-06 28.4 0.0 5.8e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EMR72857.1 - 5.4e-06 25.6 0.0 2e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EMR72857.1 - 0.0053 17.2 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain P2X_receptor PF00864.19 EMR72857.1 - 0.011 14.9 0.0 0.081 12.0 0.0 1.9 2 0 0 2 2 2 0 ATP P2X receptor p450 PF00067.22 EMR72858.1 - 4.4e-22 78.5 0.0 4.9e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CCT_2 PF09425.10 EMR72858.1 - 0.098 12.6 2.5 0.96 9.4 0.0 2.5 2 0 0 2 2 2 0 Divergent CCT motif F-box-like PF12937.7 EMR72859.1 - 0.0015 18.4 0.0 0.0037 17.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EMR72859.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.33 EMR72859.1 - 0.11 12.4 1.4 8.6 6.4 0.3 2.9 2 0 0 2 2 2 0 F-box domain CPSase_L_D2 PF02786.17 EMR72860.1 - 8.6e-70 234.5 0.0 1.3e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EMR72860.1 - 1.6e-35 121.5 0.0 4.1e-35 120.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EMR72860.1 - 7.9e-35 119.7 0.0 1.6e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EMR72860.1 - 1.2e-16 60.3 1.8 3.7e-16 58.7 1.8 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EMR72860.1 - 3.6e-07 29.9 0.0 0.0057 16.5 0.0 3.1 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EMR72860.1 - 9.4e-06 25.3 0.0 3.1e-05 23.6 0.0 1.9 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 EMR72860.1 - 0.1 13.3 0.0 19 6.0 0.0 2.8 2 0 0 2 2 2 0 HlyD family secretion protein Putative_PNPOx PF01243.20 EMR72861.1 - 8.2e-14 51.6 0.0 1.8e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EMR72861.1 - 0.00022 21.2 0.0 0.0045 17.0 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.14 EMR72861.1 - 0.047 12.1 0.1 0.055 11.9 0.1 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Ribosomal_S16 PF00886.19 EMR72862.1 - 8.6e-26 89.8 0.1 1.4e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 p450 PF00067.22 EMR72863.1 - 1.1e-38 133.2 0.1 1.3e-38 132.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3481 PF11980.8 EMR72864.1 - 0.0031 17.2 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein Myc_target_1 PF15179.6 EMR72864.1 - 0.0067 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Myc target protein 1 TMEM154 PF15102.6 EMR72864.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family LapA_dom PF06305.11 EMR72864.1 - 0.17 11.7 0.6 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Aldo_ket_red PF00248.21 EMR72865.1 - 6.8e-67 225.7 0.0 7.8e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family B12-binding PF02310.19 EMR72865.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain UbiA PF01040.18 EMR72866.1 - 5.7e-24 84.8 7.8 8e-24 84.3 7.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Cyclin_C PF02984.19 EMR72867.1 - 0.18 11.9 0.4 20 5.3 0.0 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF1471 PF07338.13 EMR72868.1 - 0.043 13.8 0.1 0.096 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) p450 PF00067.22 EMR72869.1 - 3e-40 138.4 0.0 4.1e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EMR72870.1 - 1.4e-22 79.9 0.5 2.4e-22 79.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMR72870.1 - 0.0024 17.9 0.0 0.0074 16.4 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like DNA_pol_lambd_f PF10391.9 EMR72870.1 - 0.22 11.4 0.4 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Helo_like_N PF17111.5 EMR72871.1 - 0.011 15.1 1.7 0.81 9.0 1.5 2.9 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Ribosomal_L31 PF01197.18 EMR72871.1 - 0.059 13.6 0.2 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L31 BBE PF08031.12 EMR72872.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like DUF3810 PF12725.7 EMR72873.1 - 0.0077 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Peptidase_M10 PF00413.24 EMR72873.1 - 0.034 14.0 0.0 0.092 12.6 0.0 1.6 1 1 1 2 2 2 0 Matrixin YjeF_N PF03853.15 EMR72874.1 - 1.6e-33 116.0 0.0 1.9e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus FHA PF00498.26 EMR72875.1 - 2.5e-17 63.0 0.1 8.4e-17 61.3 0.1 2.0 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EMR72875.1 - 0.00017 21.8 0.0 0.00062 20.0 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 EMR72875.1 - 0.0033 17.0 2.5 0.063 12.8 0.0 2.2 2 0 0 2 2 2 1 YhfZ C-terminal domain Cauli_AT PF03233.13 EMR72875.1 - 0.13 12.1 1.1 0.37 10.7 1.1 1.7 1 0 0 1 1 1 0 Aphid transmission protein Spc29 PF17082.5 EMR72875.1 - 0.25 11.1 5.1 0.053 13.4 1.1 1.8 2 0 0 2 2 2 0 Spindle Pole Component 29 GAS PF13851.6 EMR72875.1 - 0.39 10.0 14.2 0.1 11.9 5.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding YlqD PF11068.8 EMR72875.1 - 0.84 10.0 16.0 0.2 12.0 2.2 2.9 3 0 0 3 3 3 0 YlqD protein Cu-oxidase_3 PF07732.15 EMR72876.1 - 1.7e-44 150.6 1.5 5.1e-41 139.4 0.1 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMR72876.1 - 3.4e-33 114.3 6.4 4.3e-29 101.0 0.2 4.3 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EMR72876.1 - 5.3e-31 107.9 0.1 1.1e-30 106.9 0.1 1.6 1 0 0 1 1 1 1 Multicopper oxidase Exo_endo_phos PF03372.23 EMR72877.1 - 1.4e-05 24.7 0.0 2.9e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRN3 PF05327.11 EMR72877.1 - 0.15 10.6 1.1 0.25 9.8 1.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribosomal_S9 PF00380.19 EMR72878.1 - 4.2e-42 143.5 0.4 6.1e-42 143.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 EMR72881.1 - 7.7e-43 144.9 0.1 1.3e-42 144.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EMR72881.1 - 3.3e-15 56.1 0.1 3.3e-15 56.1 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMR72881.1 - 1.5e-12 47.7 0.0 4.2e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMR72881.1 - 4.8e-10 39.3 1.7 2.2e-09 37.2 0.1 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMR72881.1 - 2.9e-07 30.8 0.0 6.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMR72881.1 - 5.9e-07 29.6 0.1 2e-06 27.9 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMR72881.1 - 0.0016 18.7 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Vfa1 PF08432.10 EMR72882.1 - 3.2e-57 193.8 22.8 3.6e-57 193.6 22.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 MTBP_N PF14918.6 EMR72882.1 - 0.0019 17.8 2.1 0.0026 17.3 2.1 1.2 1 0 0 1 1 1 1 MDM2-binding SpoIIIAH PF12685.7 EMR72882.1 - 0.018 14.8 8.4 0.021 14.6 8.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Atrophin-1 PF03154.15 EMR72882.1 - 0.079 11.2 16.2 0.098 10.9 16.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF913 PF06025.12 EMR72882.1 - 0.43 9.5 4.4 0.47 9.4 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 EMR72882.1 - 0.59 9.9 18.4 0.75 9.6 18.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 EMR72882.1 - 1 7.7 17.7 1.2 7.6 17.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein SAPS PF04499.15 EMR72882.1 - 1.1 7.9 7.5 1.2 7.9 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.6 EMR72882.1 - 1.2 8.4 7.4 1.5 8.1 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SID-1_RNA_chan PF13965.6 EMR72882.1 - 1.3 7.4 2.0 1.4 7.3 2.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rhabdo_ncap PF00945.18 EMR72882.1 - 1.6 7.5 5.8 1.9 7.3 5.8 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Nop53 PF07767.11 EMR72882.1 - 2.5 7.4 30.4 3.3 7.0 30.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MCM_bind PF09739.9 EMR72882.1 - 2.7 6.4 8.8 2.7 6.3 8.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor GNAT_acetyltr_2 PF13718.6 EMR72882.1 - 3.6 6.9 8.7 4.6 6.6 8.7 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CDC45 PF02724.14 EMR72882.1 - 4.8 5.3 20.4 6.1 5.0 20.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EMR72882.1 - 4.9 5.1 15.4 5.7 4.9 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 EMR72882.1 - 5.2 5.1 8.8 5.8 4.9 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lipoxygenase PF00305.19 EMR72883.1 - 1.6e-17 63.2 0.0 2.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase Rtt106 PF08512.12 EMR72884.1 - 1.2e-30 105.8 0.0 2.8e-30 104.6 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EMR72884.1 - 2.7e-05 24.2 0.1 0.00019 21.4 0.0 2.4 3 1 0 3 3 3 1 Pleckstrin homology domain TFIIA PF03153.13 EMR72884.1 - 0.0055 16.8 11.6 0.008 16.2 11.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TFB6 PF17110.5 EMR72884.1 - 8.1 6.2 12.5 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH HET PF06985.11 EMR72885.1 - 5.7e-34 117.6 0.0 1e-33 116.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) S36_mt PF10937.8 EMR72886.1 - 6.1e-37 127.7 2.7 1.4e-36 126.6 2.7 1.5 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial HrpB7 PF09486.10 EMR72887.1 - 0.0092 16.4 3.6 0.018 15.5 3.6 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) RII_binding_1 PF10522.9 EMR72887.1 - 0.093 13.0 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 RII binding domain OmpH PF03938.14 EMR72887.1 - 0.13 12.6 5.9 0.1 12.9 4.5 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5093 PF17011.5 EMR72887.1 - 0.28 11.5 3.6 0.47 10.7 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) NPV_P10 PF05531.12 EMR72887.1 - 1.9 9.0 5.9 20 5.7 2.9 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MCU PF04678.13 EMR72888.1 - 3.9e-21 75.9 0.2 7.8e-21 74.9 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Abhydrolase_6 PF12697.7 EMR72889.1 - 1.1e-08 35.9 0.9 1.6e-08 35.4 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR72889.1 - 8.8e-06 25.5 0.1 2e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR72889.1 - 1.7e-05 24.2 0.0 3.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CoA_trans PF01144.23 EMR72890.1 - 2.6e-95 317.9 1.3 2.9e-59 200.1 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EMR72890.1 - 0.0039 17.1 0.1 0.0086 16.0 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Malic_M PF03949.15 EMR72890.1 - 0.077 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain VanW PF04294.13 EMR72890.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 VanW like protein MFS_1 PF07690.16 EMR72891.1 - 6.1e-38 130.6 26.4 7.8e-38 130.3 26.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMR72891.1 - 0.00025 20.8 1.7 0.00069 19.4 1.7 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF2070 PF09843.9 EMR72891.1 - 0.051 11.9 1.2 0.091 11.0 1.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Trp_oprn_chp PF09534.10 EMR72891.1 - 0.057 13.2 0.5 0.33 10.7 0.0 2.3 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Orthoreo_P10 PF07204.11 EMR72891.1 - 0.13 12.2 0.2 0.32 11.0 0.2 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 MFS_1_like PF12832.7 EMR72891.1 - 1.2 8.0 10.6 0.53 9.1 3.2 2.4 2 1 0 2 2 2 0 MFS_1 like family CMD PF02627.20 EMR72892.1 - 0.0039 17.2 0.2 0.052 13.6 0.1 2.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Tet_JBP PF12851.7 EMR72894.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Abhydrolase_6 PF12697.7 EMR72895.1 - 2.6e-08 34.7 0.7 4.4e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family AA_permease_2 PF13520.6 EMR72895.1 - 8.1e-06 24.9 10.1 8.1e-06 24.9 10.1 2.7 1 1 2 3 3 3 2 Amino acid permease AA_permease PF00324.21 EMR72895.1 - 0.00015 20.5 21.4 0.013 14.1 5.4 3.0 1 1 2 3 3 3 3 Amino acid permease ArfGap PF01412.18 EMR72896.1 - 1.4 9.0 5.1 0.44 10.6 1.1 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DAO PF01266.24 EMR72897.1 - 3e-54 185.0 2.0 3.5e-54 184.7 2.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMR72897.1 - 0.00013 22.1 0.1 0.00044 20.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMR72897.1 - 0.002 17.4 1.2 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EMR72897.1 - 0.0025 17.1 0.5 0.04 13.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMR72897.1 - 0.0031 16.7 3.0 0.054 12.6 0.4 2.3 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 EMR72897.1 - 0.0084 15.4 0.0 0.098 11.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMR72897.1 - 0.017 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.15 EMR72897.1 - 0.028 13.0 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 EMR72897.1 - 0.03 14.3 0.1 0.08 12.9 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EMR72897.1 - 0.11 11.2 0.1 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Vinculin PF01044.19 EMR72899.1 - 0.0093 14.3 0.1 0.011 14.0 0.1 1.0 1 0 0 1 1 1 1 Vinculin family DUF3716 PF12511.8 EMR72900.1 - 0.27 11.3 4.0 0.5 10.4 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Zn_clus PF00172.18 EMR72900.1 - 0.74 10.0 7.4 5.8 7.1 7.4 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2046 PF09755.9 EMR72902.1 - 0.004 16.4 1.3 0.014 14.6 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) LtuB PF17455.2 EMR72902.1 - 0.098 13.3 0.1 0.21 12.2 0.1 1.5 1 0 0 1 1 1 0 Late transcription unit B Striatin PF08232.12 EMR72902.1 - 0.14 12.8 0.1 0.14 12.8 0.1 3.1 1 1 1 2 2 2 0 Striatin family TFIIA PF03153.13 EMR72902.1 - 0.38 10.7 15.4 0.56 10.1 15.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bap31_Bap29_C PF18035.1 EMR72902.1 - 1.2 9.2 3.7 0.45 10.5 0.7 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain CASP_C PF08172.12 EMR72902.1 - 1.5 8.1 14.3 3 7.1 0.0 3.0 3 1 0 3 3 3 0 CASP C terminal Cellulase PF00150.18 EMR72903.1 - 3.6e-11 43.0 0.0 9.8e-11 41.6 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Trp_DMAT PF11991.8 EMR72904.1 - 6.3e-56 190.4 0.0 1.6e-37 129.8 0.0 2.2 1 1 1 2 2 2 2 Tryptophan dimethylallyltransferase RRM_1 PF00076.22 EMR72906.1 - 2.4e-07 30.5 0.1 4.4e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMR72906.1 - 0.00087 19.2 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CDK2AP PF09806.9 EMR72906.1 - 0.01 15.9 1.0 0.019 15.1 1.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Aldedh PF00171.22 EMR72907.1 - 3.3e-114 382.0 0.1 4e-114 381.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 EMR72909.1 - 9.9e-09 35.1 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMR72909.1 - 1.1e-08 34.8 0.2 1.9e-08 34.0 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMR72909.1 - 4.3e-05 23.5 0.1 6.8e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 EMR72909.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMR72909.1 - 0.047 14.1 0.1 0.085 13.3 0.1 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Oxidored_nitro PF00148.19 EMR72909.1 - 0.072 11.8 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Cas9_a PF18470.1 EMR72909.1 - 0.087 12.4 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain TGBp3 PF02495.17 EMR72909.1 - 0.65 9.7 3.4 0.79 9.4 0.7 2.1 2 0 0 2 2 2 0 Triple gene block 3 NRDE-2 PF08424.10 EMR72911.1 - 2.2e-41 142.1 0.5 6.2e-39 134.0 0.2 2.2 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EMR72911.1 - 0.0039 17.9 0.3 17 6.5 0.1 4.9 6 1 0 6 6 6 1 Tetratricopeptide repeat Voltage_CLC PF00654.20 EMR72912.1 - 4.8e-83 279.3 21.2 4.8e-83 279.3 21.2 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel UCR_Fe-S_N PF10399.9 EMR72912.1 - 7.9 5.9 6.5 0.25 10.7 0.2 1.8 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal HeLo PF14479.6 EMR72913.1 - 1.2e-15 57.9 0.2 1.6e-15 57.5 0.2 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation Alpha-amylase PF00128.24 EMR72913.1 - 0.086 12.4 0.1 0.14 11.7 0.1 1.4 1 1 0 1 1 1 0 Alpha amylase, catalytic domain Zincin_1 PF06262.11 EMR72913.1 - 0.16 12.1 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Zincin-like metallopeptidase Glyco_hydro_16 PF00722.21 EMR72914.1 - 8.7e-16 57.9 0.2 1.5e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RasGEF PF00617.19 EMR72915.1 - 3.2e-59 200.1 0.0 7.5e-59 198.9 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EMR72915.1 - 1.5e-28 99.1 0.3 3.7e-28 97.8 0.3 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Fungal_trans PF04082.18 EMR72916.1 - 2e-13 50.0 3.0 2.9e-13 49.5 3.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EMR72916.1 - 0.021 15.2 1.0 0.084 13.3 1.0 2.1 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMR72916.1 - 0.18 12.8 1.4 0.74 10.8 1.4 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMR72916.1 - 0.35 11.4 1.8 0.95 10.0 1.8 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type MFS_1 PF07690.16 EMR72917.1 - 5.3e-23 81.5 29.7 1.4e-12 47.3 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1688 PF07958.11 EMR72918.1 - 1.3e-183 610.6 0.0 1.4e-183 610.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TOM13 PF08219.11 EMR72919.1 - 5.7e-37 125.6 0.0 7.6e-37 125.2 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Abhydrolase_6 PF12697.7 EMR72920.1 - 2e-15 58.0 0.1 2e-15 58.0 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMR72920.1 - 2.5e-11 43.7 0.0 1.8e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMR72920.1 - 1.8e-10 40.5 0.0 1.6e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMR72920.1 - 0.0015 18.7 0.0 0.0022 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EMR72920.1 - 0.004 16.8 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EMR72920.1 - 0.0049 16.4 0.0 0.013 15.0 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF389 PF04087.14 EMR72920.1 - 0.077 13.0 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF389) BAAT_C PF08840.11 EMR72920.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal 60KD_IMP PF02096.20 EMR72921.1 - 4.6e-15 55.9 7.0 5.9e-15 55.6 7.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein adh_short PF00106.25 EMR72922.1 - 5.4e-31 107.6 0.3 8.2e-31 107.0 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72922.1 - 1.9e-23 83.3 0.0 3.3e-23 82.5 0.0 1.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72922.1 - 7.1e-08 32.6 0.1 1.1e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMR72922.1 - 2.3e-05 23.9 0.0 0.0007 19.1 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMR72922.1 - 6.3e-05 22.5 0.0 8.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMR72922.1 - 0.032 14.1 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding dbPDZ_assoc PF16610.5 EMR72922.1 - 0.058 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 FIST_C PF10442.9 EMR72922.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 FIST C domain ComA PF02679.15 EMR72923.1 - 9.7e-88 293.7 0.0 1.1e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.8 EMR72923.1 - 0.074 13.5 0.1 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) SEP PF08059.13 EMR72924.1 - 5.6e-23 81.3 0.0 1.9e-22 79.6 0.0 2.0 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 EMR72924.1 - 7.5e-11 41.7 1.7 1.3e-10 40.9 1.7 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EMR72924.1 - 1.2e-09 38.2 0.0 2.4e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 EMR72924.1 - 0.013 15.1 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 TAP C-terminal domain JSRP PF15312.6 EMR72924.1 - 0.5 10.3 2.0 6.6 6.7 0.4 2.6 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Sld5 PF05916.11 EMR72925.1 - 6.2e-28 97.4 0.0 9.4e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein adh_short PF00106.25 EMR72927.1 - 1.9e-21 76.4 0.4 2.3e-21 76.2 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMR72927.1 - 1.2e-19 70.8 0.2 1.5e-19 70.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMR72927.1 - 3.6e-06 27.0 0.1 4.5e-06 26.7 0.1 1.0 1 0 0 1 1 1 1 KR domain Spore_IV_A PF09547.10 EMR72927.1 - 0.0076 15.2 0.0 0.0096 14.9 0.0 1.0 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) 3HCDH_N PF02737.18 EMR72927.1 - 0.012 15.5 1.0 0.016 15.1 1.0 1.3 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Egh16-like PF11327.8 EMR72927.1 - 0.023 15.1 0.2 0.027 14.9 0.2 1.1 1 0 0 1 1 1 0 Egh16-like virulence factor Aldo_ket_red PF00248.21 EMR72928.1 - 1.4e-40 139.4 0.0 1.9e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family PAP2 PF01569.21 EMR72929.1 - 2.5e-21 75.8 3.2 1.3e-20 73.6 3.2 2.0 1 1 0 1 1 1 1 PAP2 superfamily DUF4389 PF14333.6 EMR72929.1 - 0.19 11.7 0.0 0.19 11.7 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) PAP2_C PF14360.6 EMR72929.1 - 1.9 9.1 6.3 0.34 11.5 2.1 2.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CK_II_beta PF01214.18 EMR72930.1 - 1.1e-76 256.7 0.2 1.4e-76 256.4 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Yip1 PF04893.17 EMR72931.1 - 1.1e-12 48.0 15.0 1.8e-12 47.3 15.0 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EMR72931.1 - 0.43 10.3 9.1 2.1 8.1 9.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) DUF2070 PF09843.9 EMR72931.1 - 9.8 4.3 14.0 5.5 5.2 9.2 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) HAD_2 PF13419.6 EMR72932.1 - 1.1e-13 51.7 0.0 1.5e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMR72932.1 - 0.00019 21.8 0.0 0.0023 18.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMR72932.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EMR72932.1 - 0.017 15.5 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EMR72933.1 - 1.1e-23 84.0 0.0 1.4e-17 64.0 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMR72933.1 - 1.9e-10 40.5 0.0 0.0023 17.3 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 EMR72933.1 - 0.0032 16.9 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMR72933.1 - 0.009 15.9 0.3 0.023 14.6 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family ABC_tran PF00005.27 EMR72934.1 - 5.6e-43 146.8 0.0 1.7e-20 73.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMR72934.1 - 1.2e-26 94.0 13.2 7.9e-25 88.0 3.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EMR72934.1 - 8e-09 35.3 0.5 0.22 11.0 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMR72934.1 - 9.3e-08 32.4 0.1 0.012 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMR72934.1 - 2.6e-07 30.3 1.4 0.012 15.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EMR72934.1 - 7.2e-07 29.3 0.1 0.057 13.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EMR72934.1 - 1.8e-06 28.4 0.8 0.023 15.1 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMR72934.1 - 5.1e-06 26.5 0.4 0.025 14.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EMR72934.1 - 8.9e-06 25.7 7.7 0.21 11.3 0.1 4.1 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EMR72934.1 - 0.00018 21.1 0.1 0.15 11.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EMR72934.1 - 0.00019 21.9 0.0 0.19 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMR72934.1 - 0.00026 21.5 0.5 1 9.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EMR72934.1 - 0.00049 20.3 1.1 0.0075 16.4 0.1 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 EMR72934.1 - 0.00073 18.7 0.1 0.21 10.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.23 EMR72934.1 - 0.00087 19.4 0.3 0.6 10.1 0.1 2.6 3 0 0 3 3 2 1 Dynamin family AAA_15 PF13175.6 EMR72934.1 - 0.0013 18.5 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EMR72934.1 - 0.0026 18.2 0.0 0.78 10.2 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EMR72934.1 - 0.0029 17.8 0.0 0.8 9.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EMR72934.1 - 0.0053 16.4 0.1 1.8 8.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EMR72934.1 - 0.0077 15.8 0.2 4.3 6.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EMR72934.1 - 0.012 15.4 0.6 14 5.4 0.0 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_10 PF12846.7 EMR72934.1 - 0.014 14.3 0.0 0.57 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.17 EMR72934.1 - 0.016 15.0 0.1 0.36 10.6 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.15 EMR72934.1 - 0.02 13.7 0.1 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Mg_chelatase PF01078.21 EMR72934.1 - 0.023 14.1 0.4 3.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 EMR72934.1 - 0.028 13.8 0.2 1.1 8.6 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EMR72934.1 - 0.041 13.6 0.4 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EMR72934.1 - 0.042 13.4 0.1 3.5 7.1 0.0 2.7 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 EMR72934.1 - 0.043 14.2 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 EMR72934.1 - 0.048 12.9 0.1 6.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Guanylate_kin PF00625.21 EMR72934.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 1 0 Guanylate kinase DUF815 PF05673.13 EMR72934.1 - 0.066 12.4 0.0 15 4.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 EMR72934.1 - 0.068 12.9 0.6 0.7 9.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 EMR72934.1 - 0.075 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EMR72934.1 - 0.085 12.9 0.1 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EMR72934.1 - 0.097 12.7 0.8 25 4.9 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EMR72934.1 - 0.17 12.2 4.4 7 7.0 0.5 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit GN3L_Grn1 PF08701.11 EMR72935.1 - 1.1e-26 92.7 17.4 2.5e-26 91.6 17.4 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EMR72935.1 - 3.7e-18 65.7 0.0 1.3e-13 51.1 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMR72935.1 - 2.6e-08 34.0 0.0 3.4e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EMR72935.1 - 3.3e-07 30.5 4.3 0.0096 16.0 0.0 3.8 4 0 0 4 4 4 2 Dynamin family GTP_EFTU PF00009.27 EMR72935.1 - 3.8e-06 26.6 0.0 0.028 14.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EMR72935.1 - 0.00043 19.8 0.1 0.038 13.5 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 EMR72935.1 - 0.037 14.4 3.8 0.15 12.4 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain Nuc_deoxyri_tr2 PF15891.5 EMR72935.1 - 0.059 13.7 1.1 0.93 9.8 0.0 2.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like cobW PF02492.19 EMR72935.1 - 0.11 12.1 0.0 1.4 8.5 0.0 2.4 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EMR72935.1 - 0.15 11.0 0.1 0.15 11.0 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB p450 PF00067.22 EMR72936.1 - 1e-41 143.2 0.0 3.6e-36 124.9 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 HcyBio PF01837.16 EMR72936.1 - 0.17 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation p450 PF00067.22 EMR72937.1 - 5.4e-71 239.7 0.0 6.3e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Eno-Rase_NADH_b PF12242.8 EMR72938.1 - 0.095 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThrE PF06738.12 EMR72939.1 - 1.1e-59 201.7 28.9 3.2e-58 196.9 9.3 2.6 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EMR72939.1 - 1.9e-08 34.5 14.6 1.9e-08 34.5 14.6 3.0 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE DHDPS PF00701.22 EMR72940.1 - 1.5e-40 138.7 0.0 1.8e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Eutypa_lata_UCREL1-UCREL1V03/GCA_000349385.1_UCREL1V03_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Eutypa_lata_UCREL1-UCREL1V03/GCA_000349385.1_UCREL1V03_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Eutypa_lata_UCREL1-UCREL1V03/GCA_000349385.1_UCREL1V03_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Eutypa_lata_UCREL1-UCREL1V03/GCA_000349385.1_UCREL1V03_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 20:02:22 2019 # [ok]